gebhart/patrepeval huggingface dataset:
Joint Inversion of MWD and wireline measurements (1999)

PreviousNext No AccessSEG Technical Program Expanded Abstracts 1999Joint Inversion of MWD and wireline measurementsAuthors: Raghu K. ChunduruAlberto G. MezzatestaHal W. MeyerZhiyi ZhangRainer BuschTom MaherRaghu K. ChunduruBaker Hughes Incorporated, Alberto G. MezzatestaBaker Hughes Incorporated, Hal W. MeyerBaker Hughes Incorporated, Zhiyi ZhangBaker Hughes Incorporated, Rainer BuschBaker Hughes Incorporated, and Tom MaherShell Offshore Inchttps://doi.org/10.1190/1.1820756 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Permalink: https://doi.org/10.1190/1.1820756FiguresReferencesRelatedDetailsCited ByNovel Approach for Evaluation of Petrophysical Parameters from Time-Lapse Induction Logging-While-Drilling Measurements in Deviated and Horizontal Wells (Russian)16 October 2017Determination of Invaded Zone Properties from Time-Lapse Induction Logging Measurements Based on Invasion Simulation and Electromagnetic Modeling (Russian)24 October 2016 SEG Technical Program Expanded Abstracts 1999ISSN (print):1052-3812 ISSN (online):1949-4645Copyright: 1999 Pages: 2061 publication data© 1999 Copyright © 1999 Society of Exploration GeophysicistsPublisher:Society of Exploration Geophysicists HistoryPublished: 04 Jan 2005 CITATION INFORMATION Raghu K. Chunduru, Alberto G. Mezzatesta, Hal W. Meyer, Zhiyi Zhang, Rainer Busch, and Tom Maher, (1999), "Joint Inversion of MWD and wireline measurements," SEG Technical Program Expanded Abstracts : 132-135. https://doi.org/10.1190/1.1820756 Plain-Language Summary PDF DownloadLoading ...
Tesseract (2019)

We propose Tesseract, a secure real-time cryptocurrency exchange service. Existing centralized exchange designs are vulnerable to theft of funds, while decentralized exchanges cannot offer real-time cross-chain trades. All currently deployed exchanges are also vulnerable to frontrunning attacks. Tesseract overcomes these flaws and achieves a best-of-both-worlds design by using a trusted execution environment. The task of committing the recent trade data to independent cryptocurrency systems presents an all-or-nothing fairness problem, to which we present ideal theoretical solutions, as well as practical solutions. Tesseract supports not only real-time cross-chain cryptocurrency trades, but also secure tokenization of assets pegged to cryptocurrencies. For instance, Tesseract-tokenized bitcoins can circulate on the Ethereum blockchain for use in smart contracts. We provide a demo implementation of Tesseract that supports Bitcoin, Ethereum, and similar cryptocurrencies.
Robust Feature Extraction for Continuous Speech Recognition Using the MVDR Spectrum Estimation Method (2006)

This paper describes a robust feature extraction technique for continuous speech recognition. Central to the technique is the minimum variance distortionless response (MVDR) method of spectrum estimation. We consider incorporating perceptual information in two ways: 1) after the MVDR power spectrum is computed and 2) directly during the MVDR spectrum estimation. We show that incorporating perceptual information directly into the spectrum estimation improves both robustness and computational efficiency significantly. We analyze the class separability and speaker variability properties of the features using a Fisher linear discriminant measure and show that these features provide better class separability and better suppression of speaker-dependent information than the widely used mel frequency cepstral coefficient (MFCC) features. We evaluate the technique on four different tasks: an in-car speech recognition task, the Aurora-2 matched task, the Wall Street Journal (WSJ) task, and the Switchboard task. The new feature extraction technique gives lower word-error-rates than the MFCC and perceptual linear prediction (PLP) feature extraction techniques in most cases. Statistical significance tests reveal that the improvement is most significant in high noise conditions. The technique thus provides improved robustness to noise without sacrificing performance in clean conditions
Spinocerebellar ataxia type 20 is genetically distinct from spinocerebellar ataxia type 5 (2006)

The autosomal dominant spinocerebellar ataxias (SCAs) are inherited neurodegenerative diseases with heterogeneous etiology and clinical presentation. The SCAs are primarily characterized by a progressive loss of coordination that affects gait, limb, and eye movement, speech, and swallowing.1 More than 28 different forms of SCA have been genetically mapped, and the number of loci responsible for SCAs continues to grow.

In 2004, a family of Anglo-Celtic origin that presented a distinct form of SCA was reported.2 In addition to the classic incoordination found among patients with ataxia, most affected family members are clinically characterized by palatal tremor and dysphonia, whereas neuroradiologic studies show calcification of the dentate nuclei, which is not found in other forms of dominant ataxia. Genetic testing demonstrated the family did not carry the mutation for SCA1, 2, 3, 6 to 8, or 17, and linkage …
The rat extracellular superoxide dismutase dimer is converted to a tetramer by the exchange of a single amino acid. (1996)

Extracellular superoxide dismutase (EC-SOD) is a secreted Cu and Zn-containing glycoprotein. While EC-SOD from most mammals is tetrameric and has a high affinity for heparin and heparan sulfate, rat EC-SOD has a low affinity for heparin, does not bind to heparan sulfate in vivo, and is apparently dimeric. To examine the molecular basis of the deviant physical properties of rat EC-SOD, the cDNAs of the rat and mouse EC-SODs were isolated and the deduced amino acid sequences were compared with that of human EC-SOD. Comparison of the sequences offered no obvious explanation of the differences. Analysis of a series of chimeric and point mutated EC-SODs showed that the N-terminal region contributes to the oligomeric state of the EC-SODs, and that a single amino acid, a valine (human amino acid position 24), is essential for the tetramerization. This residue is replaced by an aspartate in the rat. Rat EC-SOD carrying an Asp --> Val mutation is tetrameric and has a high heparin affinity, while mouse EC-SOD with a Val --> Asp mutation is dimeric and has lost its high heparin affinity. Thus, the rat EC-SOD dimer is converted to a tetramer by the exchange of a single amino acid. Furthermore, the cooperative action of four heparin-binding domains is necessary for high heparin affinity. These results also suggest that tetrameric EC-SODs are not symmetrical tetrahedrons, but composed of two interacting dimers, further supporting an evolutionary relationship with the dimeric cytosolic Cu and Zn-containing SODs.
Laser monitoring of mass concentrations of monodisperse test aerosols (1980)

Aerosol sampling is a complicated problem in aerosol physics. A technique described to monitor continuously the mass concentration of monodisperse test aerosols using a He-Ne laser. Good approximations are possible from Mie theory. The method is fast, accurate, and eliminates the need for precalibration of a standard sampler to monitor aerosol mass concentration over increments of time. It can be used for sampler efficiency measurements and wherever it is desired to monitor test aerosols of spherical droplets continuously, e.g., in studies of the human respiratory system for droplets larger than a few micrometers.
Exosomes derived from human adipose tissue-derived mesenchymal stem cells alleviate atopic dermatitis (2018)

Exosomes are nano-sized vesicles (30-200 nm) constantly released by almost all cells. The ability of exosomes to travel between cells and deliver their cargo, which includes lipids, proteins, and nucleic acids, makes them an appealing cell-free therapy option to treat multiple diseases. Here, we investigated for the first time whether human adipose tissue-derived mesenchymal stem cell-derived exosomes (ASC-exosomes) can ameliorate atopic dermatitis (AD) in an in vivo mouse model. When injected either intravenously (IV) or subcutaneously (SC) into NC/Nga mice treated with house dust mite antigens, ASC-exosomes were found to reduce pathological symptoms such as clinical score, the levels of serum IgE, the number of eosinophils in blood, and the infiltration of mast cells, CD86+, and CD206+ cells in skin lesions. ASC-exosomes also significantly reduced mRNA expression of various inflammatory cytokines such as interleukin (IL)-4, IL-23, IL-31, and tumor necrosis factor-α (TNF-α) in AD skin lesions of Nc/Nga mice. Taken together, these results suggest that ASC-exosomes can be a novel promising cell-free therapeutic modality for AD treatment.
Spatial Effects (2011)

This chapter contains sections titled: Introduction Concepts of spatial hearing Basic spatial effects for stereophonic loudspeaker and headphone playback Binaural techniques in spatial audio Spatial audio effects for multichannel loudspeaker layouts Reverberation Modeling of room acoustics Other spatial effects Conclusion Acknowledgements References
Delayed Expression of Adeno-Associated Virus Vector DNA (1999)

Two previous reports indicated that recombinant adeno-associated virus (rAAV) vectors were dependent on helper adenovirus (Ad) for efficient conversion of single-stranded (ss) rAAV DNA to the double-stranded (ds) form. This finding is somewhat paradoxical, however, since during a latent infection wild-type (wt)-AAV is rapidly converted to a ds form in the absence of Ad. Our hypothesis was that the effect observed in the previous studies was due to kinetic factors, i.e. to a relative delay in conversion to ds-DNA rather than to an absolute requirement for Ad. To test this, Hela cells were infected with a rAAV-CMV-green fluorescent protein (GFP) vector either in the presence or absence of Ad. Within the first 2 days, Ad infection resulted in a 4-fold increase in AAV vector expression and an augmentation of conversion to a ds-AAV DNA. By 6 days, however, the total number of GFP-expressing cells in the Ad-free culture had exceeded the original number in the Ad co-infected cells, and the conversion to ds-DNA episomes was substantial and ongoing.
I Can Parse You: Grammars for Dialogs (2017)

Humans and computers increasingly converse via natural language. Those conversations are moving from today's simple question answering and command-and-control to more complex dialogs. Developers must specify those dialogs. This paper explores how to assist developers in this specification. We map out the staggering variety of applications for human-computer dialogs and distill it into a catalog of flow patterns. Based on that, we articulate the requirements for dialog programming models and offer our vision for satisfying these requirements using grammars. If our approach catches on, computers will soon parse you to better assist you in your daily life.
Pulsed Heat Transfer for Thermal Maximum Power Point Tracking (2013)

This paper presents a new method for enhancing thermal energy harvesting via pulsed heat transfer. By acting as a variable thermal resistance that theoretically generates no entropy, a pulsed thermal connection allows calibration of the effective thermal resistance of an energy harvesting system. By adjusting the frequency and duty cycle of the pulsed heat transfer, the method allows an energy harvester to be continuously optimized for a variable incident heat flux. In this paper, the analysis of a generalized model shows how the pulse strategy theoretically allows any heat engine-heat sink pair to work at the same power and efficiency as a 1:1 thermal resistance-matched engine-heat sink pair of equal or greater total thermal resistance. Experiments with a mechanical thermal switch validate this model, and show how the pulse strategy can improve the efficiency of a system with equal engine and heat sink thermal resistances by over 80% with no increase in the hot-side maximum temperature, although at reduced total power. At a 1:2 engine-sink resistance ratio, the improvement can simultaneously exceed 60% in power and 15% in efficiency. The thermal pulse strategy could be implemented to improve of a variety of systems that convert thermal energy, from waste heat harvesters to the radioisotope power systems on many spacecraft.
Inter-Numerology Interference Management With Adaptive Guards: A Cross-Layer Approach (2020)

The next-generation communication technologies are evolving towards increased flexibility in various aspects. Although orthogonal frequency division multiplexing (OFDM) remains as the waveform of the upcoming fifth-generation (5G) standard, the new radio provides flexibility in waveform parametrization (a.k.a. numerology) to address diverse requirements. However, managing the peaceful coexistence of mixed numerologies is challenging due to inter-numerology interference (INI). This paper proposes the utilization of adaptive guards in both time and frequency domains as a solution along with a multi-window operation in the physical (PHY) layer. The adaptive windowing operation needs a guard duration to reduce the unwanted emissions, and a guard band is required to handle the INI level on the adjacent band. The guards in both domains are jointly optimized with respect to the subcarrier spacing, use case (i.e., service requirement), and power offset between the numerologies. Also, the multi-window approach provides managing each side of the spectrum independently in case of an asymmetric interference scenario. Since the allowed interference level depends on the numerologies operating in the adjacent bands, the potential of adaptive guards is further increased and exploited with a medium access control (MAC) layer scheduling technique. The proposed INI-based scheduling algorithm decreases the need for guards by allocating the numerologies to the available bands, considering their subcarrier spacing, power level, and SIR requirements. Therefore, INI management is performed with a cross-layer (PHY and MAC) approach in this study. The results show that the precise design that accommodates such flexibility reduces the guards significantly and improves the spectral efficiency of mixed numerology systems.
A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products (2019)

Diterpenoids form a diverse class of small molecule natural products that are widely distributed across the kingdoms of life and have critical biological functions in developmental processes, interorganismal interactions, and environmental adaptation. Due to these various bioactivities, many diterpenoids are also of economic importance as pharmaceuticals, food additives, biofuels, and other bioproducts. Advanced genomics and biochemical approaches have enabled a rapid increase in the knowledge of diterpenoid-metabolic genes, enzymes, and pathways. However, the structural complexity of diterpenoids and the narrow taxonomic distribution of individual compounds in often only a single species remain constraining factors for their efficient production. Availability of a broader range of metabolic enzymes now provide resources for producing diterpenoids in sufficient titers and purity to facilitate a deeper investigation of this important metabolite group. Drawing on established tools for microbial and plant-based enzyme co-expression, we present an easily operated and customizable protocol for the enzymatic production of diterpenoids in either Escherichia coli or Nicotiana benthamiana, and the purification of desired products via silica chromatography and semi-preparative HPLC. Using the group of maize (Zea mays) dolabralexin diterpenoids as an example, we highlight how modular combinations of diterpene synthase (diTPS) and cytochrome P450 monooxygenase (P450) enzymes can be used to generate different diterpenoid scaffolds. Purified compounds can be used in various downstream applications, such as metabolite structural analyses, enzyme structure-function studies, and in vitro and in planta bioactivity experiments.
The design of an asynchronous microprocessor (1989)

article Free Access Share on The design of an asynchronous microprocessor Authors: Alain J. Martin California Institute of Technology, Pasadena, CA 91125 California Institute of Technology, Pasadena, CA 91125View Profile , Steven M. Burns 1186643 1186643View Profile , T. K. Lee 1186643 1186643View Profile , Drazen Borkovic California Institute of Technology, Pasadena, CA 91125 California Institute of Technology, Pasadena, CA 91125View Profile , Pieter J. Hazewindus California Institute of Technology, Pasadena, CA 91125 California Institute of Technology, Pasadena, CA 91125View Profile Authors Info & Claims ACM SIGARCH Computer Architecture NewsVolume 17Issue 4June 1989 pp 99–110https://doi.org/10.1145/71317.1186643Published:02 June 1989Publication History 0citation201DownloadsMetricsTotal Citations0Total Downloads201Last 12 Months14Last 6 weeks5 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Highly efficient, spatially coherent distributed feedback lasers from dense colloidal quantum dot films (2013)

Colloidal quantum dots (CQD) are now making their entry to full-color displays, endowed by their brightness and single-material base. By contrast, many obstacles have been encountered in their use towards lasers. We demonstrate here optically pumped distributed feedback (DFB) lasers, based on close-packed, solid films self-assembled from type-I CQDs. Notably, the single mode CQD-DFB lasers could reach such a low threshold as to be pumpable with a compact pulsed source in a quasi-continuous wave regime. Our results show the spatially and temporally coherent laser beam outputs with power of 400 μW and a quantum efficiency of 32%.
Efficient Solution‐Processed Bulk Heterojunction Perovskite Hybrid Solar Cells (2015)

Efficient conventional bulk heterojunction (BHJ) perovskite hybrid solar cells (pero‐HSCs) solution‐processed from a composite of CH 3 NH 3 PbI 3 mixed with PC 61 BM ([6,6]‐phenyl‐C61‐butyric acid methyl ester), where CH 3 NH 3 PbI 3 acts as the electron donor and PC 61 BM acts as the electron acceptor, are reported for the first time. The efficiency of 12.78% is twofold enhancement in comparison with the conventional planar heterojunction pero‐HSCs (6.90%) fabricated by pristine CH 3 NH 3 PbI 3 . The BHJ pero‐HSCs are further optimized by using PC 61 BM/TiO 2 bi‐electron‐extraction‐layer (EEL), which are both solution‐processed and then followed with low‐temperature thermal annealing. Due to higher electrical conductivity of PC 61 BM over that of TiO 2 , an efficiency of 14.98%, the highest reported efficiency for the pero‐HSCs without incorporating high‐temperature‐processed mesoporous TiO 2 and Al 2 O 3 as the EEL and insulating scaffold, is observed from PC 61 BM modified BHJ pero‐HSCs. Thus, the findings provide a simple way to approach high efficiency low‐cost pero‐HSCs.
Frugal channel tracking for transmit beamforming (2014)

Channel state feedback is a serious burden for transmit beamforming systems with many antennas in FDD mode. Instead of estimating the channel at the receiver and feeding back quantized beamformer information, a different approach that exploits the spatio-temporal correlation of the channel is proposed. The transmitter periodically sends a beamformed pilot signal, while the receiver feeds back the quantized innovation derived from either a Kalman filtering or a MAP tracking loop. Simulations show that close to optimum performance can be attained with only 2 bits per channel dwell, clearing a hurdle for transmit beamforming with many antennas in FDD mode.
A Practical Synthesis of the Kappa Opioid Receptor Selective Agonist (+)-5<b><i>R</i></b>,7<b><i>S</i></b>,8<b><i>S</i></b>-<b><i>N</i></b>-Methyl-<b><i>N</i></b>-[7-(1-pyrrolidinyl)-1-oxospiro[4,5]dec-8-yl]benzeneacetamide (U69,593) (2008)

A novel approach to the synthesis of the kappa opioid receptor agonist U69,593 has been developed. This approach improves upon current literature methods by substituting stable and isolable cyclic sulfates for the unstable epoxides. The new approach provides access to gram quantities of the target compound and displays excellent control of the relative stereochemistry. The absolute stereochemistry as well as biological activity of the U69,593 produced by this new method was verified using X-ray crystal structure analysis and binding assays for the kappa opioid receptor.
Analysis of Variation in cis-9, trans-11 Conjugated Linoleic Acid (CLA) in Milk Fat of Dairy Cows (2002)

Conjugated linoleic acid (CLA) is a fatty acid with numerous putative health benefits and is a natural component of ruminant-derived food products. An intermediate in rumen biohydrogenation is cis-9, trans-11 CLA, the major CLA isomer in milk fat. However, the major source of cis-9, trans-11 CLA in milk is endogenous synthesis by delta 9-desaturase conversion of trans-11 C18:1, another rumen biohydrogenation intermediate. The desaturase indices serve as a proxy for delta 9-desaturase activity and are calculated from the ratios of fatty acid pairs that represent product/substrate for this enzyme. This study analyzed individual animal variation in milk fat content of cis-9, trans-11 CLA and in desaturase indices in milk fat. Thirty lactating Holstein cows were allocated to one of three treatment groups: one received a standard total mixed ration, one received a diet that produced an elevated milk fat content of CLA, and a third treatment group was alternated between these diets at 3-wk intervals over the 12-wk study. There was a two- to threefold variation among individuals on the same diet for both milk fat content of CLA and desaturase indices in milk fat. This hierarchy was maintained to a large extent over the 12-wk study even in the variable treatment group that alternated between the two diets. Within the variable diet treatment, some animals consistently had a substantial response in milk fat content of CLA to dietary shifts, whereas other cows had little or no response. We conclude that while diet is a major determinant of the CLA content in milk fat, individual animal differences also have a substantial effect. The variation among individuals includes differences related to both rumen biohydrogenation and delta 9-desaturase activity in the mammary gland.
Modeling memory bandwidth patterns on NUMA machines with performance\n counters (2021)

Computers used for data analytics are often NUMA systems with multiple\nsockets per machine, multiple cores per socket, and multiple thread contexts\nper core. To get the peak performance out of these machines requires the\ncorrect number of threads to be placed in the correct positions on the machine.\nOne particularly interesting element of the placement of memory and threads is\nthe way it effects the movement of data around the machine, and the increased\nlatency this can introduce to reads and writes. In this paper we describe work\non modeling the bandwidth requirements of an application on a NUMA compute node\nbased on the placement of threads. The model is parameterized by sampling\nperformance counters during 2 application runs with carefully chosen thread\nplacements. Evaluating the model with thousands of measurements shows a median\ndifference from predictions of 2.34% of the bandwidth. The results of this\nmodeling can be used in a number of ways varying from: Performance debugging\nduring development where the programmer can be alerted to potentially\nproblematic memory access patterns; To systems such as Pandia which take an\napplication and predict the performance and system load of a proposed thread\ncount and placement; To libraries of data structures such as Parallel\nCollections and Smart Arrays that can abstract from the user memory placement\nand thread placement issues when parallelizing code.\n