gebhart/patrepeval huggingface dataset:
Electromagnetic Induction Position Sensor Applied to Anti-Misalignment Wireless Charging for UAVs (2019)

Misalignment of wireless power transfer (WPT) system's transmitting and receiving ends can cause severe efficiency degradation and electromagnetic radiation. In this paper, a novel parallel transmission (TX) coil matrix structure was proposed to improve the performance of the WPT in the misalignment condition. The receiving (RX) coil's position measurement method was innovated by investigating the magnetic field and the mutual inductance change caused by the relative position change between RX and TX coils. Both theory and experiments confirmed that the phase difference between signal coil and detector coil can be featured as the parameter to represent the magnetic field's change. Based on this principle, a 4×4 TX coil matrix was made which verified the proposal and the sensitivity of the sensor. It was found that the position measurement result was sufficient to decide which TX coil to gate to facilitate the wireless charging in misalignment conditions. The structure and the size of the TX coil matrix could be further optimized to enhance the sensor's reliability and sensitivity.
Protein unfolding during reversed‐phase chromatography: II. Role of salt type and ionic strength (2001)

While reversed-phase chromatography (RPC) may be a powerful method for purification of proteins at the analytical scale, both preparative and analytical applications have been hindered by the complex chromatographic behavior of proteins compared to small molecules. Further, preparative applications have been limited because of poor yields caused by the denaturing conditions involved. One means for modulating both the stability and chromatographic behavior of proteins is through the use of added salt. In this investigation, we show how salt type and ionic strength affect protein conformation on RPC surfaces. Exposure of amide groups of adsorbed BPTI was monitored using nuclear magnetic resonance (NMR) spectroscopy and hydrogen-deuterium isotope exchange. Sodium chloride, sodium acetate, and ammonium sulfate were studied at ionic strengths up to I = 0.375, with adsorption hold times being 5 min and 2 h. We found that increasing ionic strength decreased exposure of the exchange reporter groups in essentially all cases. However, even at the same ionic strength the level and distribution of residue protection varied with salt type and hold time. NaCl does not protect certain reporter groups at all, while those that it does protect to some degree at short hold times can exchange slightly more at longer times. The pattern and level of protection for NaAc at short times is similar to that for NaCl, but at longer times more uniform protection is seen as the reporter groups completely exposed at short times become more protected. For (NH(4))(2)SO(4) the pattern of protection at short hold time is similar to those of the other salts, although it protects all groups much more. This would be expected from the Hofmeister series. However, at longer times the level of protection with (NH(4))(2)SO(4) decreases below that of the other salts, while it uniquely protects all groups to nearly the same level. Such subtle variations in the protein structure would not have been detected without the measurements and analysis used here. Chromatographic retention times and peak shapes were obtained for the above systems. Variations of behavior were seen that could not be correlated with any of the above protection patterns and levels or even with heuristics such as the Hofmeister series. This suggests further conformational changes upon elution may be critical to the retention process. However, an excellent correlation was found between peak width at half-height and the average degree of unfolding, as indicated by the average level of isotopic exchange. Thus, while further studies are needed to definitively determine the connection between protein unfolding and retention, use of this correlation may improve designing and screening for chromatographic conditions that minimize protein unfolding.
Plastic scintillation dosimetry: optimization of light collection efficiency (2003)

Practical contemporary radiotherapy dosimetry systems used for dose measurement and verification are ionization chambers (which typically have at least a 0.1 cm3 air cavity volume), thermoluminescent dosimeters (TLDs) and silicon diodes. However, during the last decade, there has been an increased interest in scintillation dosimetry using small water-equivalent plastic scintillators, due to their favourable characteristics when compared with other more commonly used detector systems. Although plastic scintillators have been shown to have many desirable dosimetric properties, as yet there is no successful commercial detector system of this type available for routine clinical use in radiation oncology. The objectives of this study are to identify the factors preventing this new technology from realizing its full potential in commercial applications. A definition of signal to noise ratio (S/N) will be proposed for this category of detectors. In doing so the S/N ratio for an early prototype design has been calculated and/or measured. Criteria to optimize the response and sensitivity of this category of detectors are presented.
Biochemical and Genetic Studies of the Initiation of Human Rhinovirus 2 RNA Replication: Identification of a <i>cis</i> -Replicating Element in the Coding Sequence of 2A <sup>pro</sup> (2001)

We have previously shown that the RNA polymerase 3D(pol) of human rhinovirus 2 (HRV2) catalyzes the covalent linkage of UMP to the terminal protein (VPg) using poly(A) as a template (K. Gerber, E. Wimmer, and A. V. Paul, J. Virol. 75:10969-10978, 2001). The products of this in vitro reaction are VPgpU, VPgpUpU, and VPg-poly(U), the 5' end of minus-strand RNA. In the present study we used an assay system developed for poliovirus 3D(pol) (A. V. Paul, E. Rieder, D. W. Kim, J. H. van Boom, and E. Wimmer, J. Virol. 74: 10359-10370, 2000) to search for a viral sequence or structure in HRV2 RNA that would provide specificity to this reaction. We now show that a small hairpin in HRV2 RNA [cre(2A)], located in the coding sequence of 2A(pro), serves as the primary template for HRV2 3D(pol) in the uridylylation of HRV2 VPg, yielding VPgpU and VPgpUpU. The in vitro reaction is strongly stimulated by the addition of purified HRV2 3CD(pro). Our analyses suggest that HRV2 3D(pol) uses a "slide-back" mechanism during synthesis of the VPg-linked precursors. The corresponding cis- replicating RNA elements in the 2C(ATPase) coding region of poliovirus type 1 Mahoney (I. Goodfellow, Y. Chaudhry, A. Richardson, J. Meredith, J. W. Almond, W. Barclay, and D. J. Evans, J. Virol. 74:4590-4600, 2000) and VP1 of HRV14 (K. L. McKnight and S. M. Lemon, RNA 4:1569-1584, 1998) can be functionally exchanged in the assay with cre(2A) of HRV2. Mutations of either the first or the second A in the conserved A(1)A(2)A(3)CA sequence in the loop of HRV2 cre(2A) abolished both viral growth and the RNA's ability to serve as a template in the in vitro VPg uridylylation reaction.
Survey of glycoantigens in cells from α1-3galactosyltransferase knockout pig using a lectin microarray (2010)

It is possible that the T-antigen and Tn-antigen related to GalNAc are non-Gal antigens, but, fortunately, not only alpha-Gal but also GalNAc were found to be decreased in the KO-pig.
SimParallel: A high performance parallel SystemC simulator using hierarchical multi-threading (2014)

As the system complexity increases, the simulation performance becomes one of the most important issues in virtual prototyping. Parallel simulation is a fascinating technique for high-speed simulation utilizing state of the art multi-core processors on a host workstation, but the efficiency of the parallel simulation is low because of the synchronization and communication overhead and unbalanced workloads among cores in the host. This paper proposes a novel technique, hierarchical multi-threading for the efficient parallel simulation of SystemC models where the host cores are able to be maximally utilized with the same number of thread groups. We also present an efficient synchronization and dynamic load balancing scheme for the proposed parallel simulation. Experimental results show that the proposed method achieves speed-up of from 2.9 to 3.3 in quad-core host workstation.
Cytotoxicity of platelet activating factor and related alkyl- phospholipid analogs in human leukemia cells, polymorphonuclear neutrophils, and skin fibroblasts (1984)

A series of 11 alkyl-phospholipid analogs, structurally related to platelet activating factor (L-PAF), were analyzed for cytotoxic activity in human leukemic (HL-60) cells, human polymorphonuclear neutrophils, and Detroit 551 human skin fibroblasts. The order of selectiveness of the analogs in their cytotoxic response toward HL-60 cells in comparison to neutrophils is 1-alkyl-2-acetamide-GPC greater than 1-alkyl-2-methoxy-GPC greater than D-PAF greater than 1-acyl-2-lyso-GPC greater than 1-alkyl-2-lyso-GPC greater than L-PAF. A time-sequenced progression of events caused by the most potent cytotoxic alkyl-phospholipid analogs was characterized by (a) a rapid decrease in the cellular uptake and incorporation of 3H-thymidine into DNA that was detectable 4 hr after exposure to the analog, (b) a release of lactate dehydrogenase activity into the media at 8 hr after exposure, and (c) a decrease in cell number due to cell death that begins at 12 hr after exposure. Treatment of HL-60 cells with 1-alkyl-2-methoxy-GPC for 1 hr destroyed 40% of the cells after a subsequent 24-hr incubation period. The varied biologic activities of L-PAF, including how it affects serotonin release from platelets, blood pressure in rats, and cytotoxic responses in normal and leukemic cells, are discussed in relation to its D-enantiomer, 3-alkyl-2-acetyl-GPC, and the 2-acetamide analog. This report characterizes the kinetic events of the cellular responses in both normal and HL-60 cells in relation to the antineoplastic activities of unnatural ether-linked phospholipid analogs that are structurally related to L-PAF.
Editorial: ICT for Education and Training (2006)

Welcome to Volume 2, Issue 4 of the International Journal of and Development using Information and Communication Technology (IJEDICT). This issue contains articles concerned with using information and communication technologies (ICT) in educational settings so as to empower local communities. It brings articles from and/or about Australia, Barbados, Canada, Eritrea, India, Nigeria, South Africa and the Sultanate of Oman. A major focus of this journal is on the utilisation of responsive and localised ICT for the socioeconomic empowerment of rural communities. This is also the focus Ganga Prasad GL, Amitav Nath and Rakesh Mishra in their article Community content sharing: Towards telecentre's Lab to Land approach. They explain the methodology of lab to land adopted by the ICT RT and the second stage evaluated the diagnostic value of data that CAA produces. While results confirmed earlier findings about the advantages of CAA, the diagnostic and remediation potential of CAA data depended upon teachers' capacity to set diagnostic test items particularly in a multiple-choice format, teachers' ability to interpret data produced by CAA, teachers' skills in remedying their classroom as well as learners' problems, the quality of the test items, and the learning as well as the teaching strategies. Ravinder Rena, in Education and human resource development in post-independent Eritrea: An explanatory note describes how the Government of Eritrea is offering both formal and informal training programmes at different levels in order to develop human resources in the country. The author analyses the educational and human resource development after independence, and also provides a detailed account of technical and vocation education with special reference to skill development programme. In Impact of WebCT on learning: An Oman experience, Syed Naqvi describes a study that investigated the impact of WebCT on students learning taking a course Introduction to Computers in Business offered at the College of Commerce and Economics, Sultan Qaboos University in the Sultanate of Oman. …
L’archiviste et la négation du temps (2012)

Les archives ont déjà fait couler beaucoup d’encre grâce aux archivistes euxmêmes, avec leur propre littérature technique et théorique, et grâce au monde académique. À commencer par les historiens, utilisateurs singuliers qui ont tantôt porté un regard esthétique sur la relation au document, tantôt critique\nsur les conditions d’accès à leur communication quand ils n’interrogent pas l’histoire et la variation du lieu d’archive. (Premières lignes)
Ocean heave cancellation for a maritime infrasound sensor (2016)

Infrasound is very low frequency airborne acoustic energy in the frequency band of 3.3 mHz to 20 Hz, that is inaudible to human beings. Natural sources of infrasound include earthquakes, meteors, volcanoes, tsunamis, auroras, and ocean swells. Among anthropogenic sources are atmospheric and underground nuclear explosions. Because of their low frequency, infrasound waves experience little attenuation, and can therefore propagate to, and be detectable from, very long distances. Land-based infrasound microbarometer sensors and networks have the capability of detecting these signals. In this paper, we investigate the fielding of microbarometer sensors in the maritime environment, on boats, buoys, or unmanned surface vehicles (USV). A particular problem to be overcome is the effect of ocean heave on sensor performance. Ocean heave induces interfering pressure fluctuations on the sensor which may obscure the infrasound signal of interest. In this paper, an ocean-heave cancellation method is developed and applied to infrasound data collected with a sensor deployed onboard a ship at sea. The results show the performance of this approach in cancelling ocean heave-induced interference on infrasound sensors fielded in the maritime environment.
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Testing deviations from the $\mathrm{\ensuremath{\Lambda}}\mathrm{CDM}$ model using the cosmic microwave background power spectra requires a pristine understanding of instrumental systematics. In this work, we discuss the properties of the observable ${\mathcal{R}}_{\ensuremath{\ell}}^{TE}$, the correlation coefficient of temperature and E modes. We find that this observable is mostly unaffected by systematics introducing multiplicative biases such as errors in calibration, polarization efficiency, beam and transfer function measurements. We discuss the dependency of this observable on the cosmological model and derive its statistical properties. We then compute the $TE$ correlation coefficients of Planck legacy data and compare them with expectations from the Planck best fit $\mathrm{\ensuremath{\Lambda}}\mathrm{CDM}$ and foreground model.
Thidiazuron‐induced somatic embryogenesis in intact seedlings of peanut (<i>Arachis hypogaea</i>): Endogenous growth regulator levels and significance of cotyledons (1995)

The regulatory role of thidiazuron (TDZ) and explant factors in imparting somatic embryogenic potential was assessed in relation to endogenous growth regulator levels in peanut ( Arachis hypogaea L. cv. Tango). TDZ induced somatic embryogenesis over a range of concentrations (0.5 to 10 μ M ). Culture of seedlings for just 2 days on TDZ‐supplemented medium was sufficient to induce somatic embryogenesis. Seedling age and retention or removal of cotyledons during culture influenced morphogenic potential significantly. The younger the seedlings, the better was the embryogenic response to TDZ treatment. The embryogenic potential of seedlings was limited for explants with no cotyledons and they did not respond to increasing levels of TDZ. In contrast, retention of at least one or both the cotyledons resulted in increased response to TDZ. Endogenous levels of cytokinins, auxins and abscisic acid were influenced by TDZ treatment, while TDZ itself was detected only in the cotyledons. The cytokinin N 6 ‐(2‐iso‐pentenyl)adenine (2iP) fluctuated on a 10‐day cycle in the cotyledons; TDZ treatment suppressed this change and caused an overall decrease in the pool of available 2iP in the tissue. It appeared that TDZ induced somatic embryogenesis in peanut by influencing endogenous levels of both auxin and cytokinins.
Nanogels for Pharmaceutical and Biomedical Applications and Their Fabrication Using 3D Printing Technologies (2018)

Nanogels are hydrogels formed by connecting nanoscopic micelles dispersed in an aqueous medium, which give an opportunity for incorporating hydrophilic payloads to the exterior of the micellar networks and hydrophobic payloads in the core of the micelles. Biomedical and pharmaceutical applications of nanogels have been explored for tissue regeneration, wound healing, surgical device, implantation, and peroral, rectal, vaginal, ocular, and transdermal drug delivery. Although it is still in the early stages of development, due to the increasing demands of precise nanogel production to be utilized for personalized medicine, biomedical applications, and specialized drug delivery, 3D printing has been explored in the past few years and is believed to be one of the most precise, efficient, inexpensive, customizable, and convenient manufacturing techniques for nanogel production.
1997年度談話会・特別講演アブストラクト集 Colloquium Lectures 北海道大学理学部数学教室 (1998)

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Efficient fine-grained shared buffer management for multiple OpenCL devices (2013)

OpenCL programming provides full code portability between different hardware platforms, and can serve as a good programming candidate for heterogeneous systems, which typically consist of a host processor and several accelerators. However, to make full use of the computing capacity of such a system, programmers are requested to manage diverse OpenCL-enabled devices explicitly, including distributing the workload between different devices and managing data transfer between multiple devices. All these tedious jobs pose a huge challenge for programmers. In this paper, a distributed shared OpenCL memory (DSOM) is presented, which relieves users of having to manage data transfer explicitly, by supporting shared buffers across devices. DSOM allocates shared buffers in the system memory and treats the on-device memory as a software managed virtual cache buffer. To support fine-grained shared buffer management, we designed a kernel parser in DSOM for buffer access range analysis. A basic modified, shared, invalid cache coherency is implemented for DSOM to maintain coherency for cache buffers. In addition, we propose a novel strategy to minimize communication cost between devices by launching each necessary data transfer as early as possible. This strategy enables overlap of data transfer with kernel execution. Our experimental results show that the applicability of our method for buffer access range analysis is good, and the efficiency of DSOM is high.
Analysis of correlation between mitotic index, MIB1 score and S-phase fraction as proliferation markers in invasive breast carcinoma. Methodological aspects and prognostic value in a series of 257 cases. (2004)

A good level of correlation was observed between the values of the three markers of tumour cell proliferation analysed. In this series of invasive breast cancers, MIB1 immunostaining was found to be a prognostic marker of both OS and DFS. The median (32.4%) was a valuable cut-off value for prognostic assessment. Semi-quantitative and quantitative evaluations provided very similar values. MIB1 can thus be considered as a reliable prognostic maker, usable in small size tissue specimens which are inappropriate for MI or SPF analysis. The impact of MIB1 compared to that of the other proliferative markers will be further assessed in a subgroup of T1N0M0 for which the prognostic assessment is of major interest.
Nuclear Import of IκBα Is Accomplished by a Ran-Independent Transport Pathway (2000)

The inhibitor of kappa B alpha (IkappaBalpha) protein is able to shuttle between the cytoplasm and the nucleus. We have utilized a combination of in vivo and in vitro approaches to provide mechanistic insight into nucleocytoplasmic shuttling by IkappaBalpha. IkappaBalpha contains multiple functional domains that contribute to shuttling of IkappaBalpha between the cytoplasm and the nucleus. Nuclear import of IkappaBalpha is mediated by the central ankyrin repeat domain. Similar to previously described nuclear import pathways, nuclear import of IkappaBalpha is temperature and ATP dependent and is blocked by a dominant-negative mutant of importin beta. However, in contrast to classical nuclear import pathways, nuclear import of IkappaBalpha is independent of soluble cytosolic factors and is not blocked by the dominant-negative RanQ69L protein. Nuclear export of IkappaBalpha is mediated by an N-terminal nuclear export sequence. Nuclear export of IkappaBalpha requires the CRM1 nuclear export receptor and is blocked by the dominant-negative RanQ69L protein. Our results are consistent with a model in which nuclear import of IkappaBalpha is mediated through direct interactions with components of the nuclear pore complex, while nuclear export of IkappaBalpha is mediated via a CRM1-dependent pathway.
Influence Of Particles/Impurity Metals In RCA Cleaning Solutions On Surface Contamination. (2005)

We investigated how the particles and the metals in RCA cleaning solutions contaminate wafer surfaces in 64M DRAM development process. The most dominant factor to keep the cleanliness of wafer in present process is the overall cleanliness of the system, rather than the purity of chemicals itself. The residual contamination on wafers can be kept below detection limits by optimizing the cleaning process and its operation parameters. Therefore the requirements of quality levels for the fed chemicals are supposed not so high for the present 64M DRAM development process.