gebhart/patrepeval huggingface dataset:
A programmable motion estimation processor for full search block matching (2002)

Describes a programmable motion estimation processor applying a block matching technique on large search windows. Developed in the context of an MPEG-2 video encoder, its use can be extended to any application where fast motion estimation is required. Its high performance (17 Gops peak) and its ability to work in parallel make it ideal for real time applications like video compression. The block matching processor (BMP) consists of a CPU associated with several specific units including a fast motion estimator, a DRAM interface, IO ports and some on-chip memory. This approach allies the flexibility of a CPU to the efficiency of dedicated hardware. A DRAM controller minimizes the impact of data transfer on the computing power.
A review of current developments in non-aqueous redox flow batteries: characterization of their membranes for design perspective (2013)

The non-aqueous redox flow battery (RFB) is one of the emerging large-scale energy storage systems that may overcome the low energy density limited by breakdown of water at a high voltage in aqueous RFBs. Yet development of the non-aqueous RFB is at an early stage, so its components are not thoroughly understood. As a key component of non-aqueous RFBs, the role of the membrane is to suppress cross-contamination between the anolyte and catholyte confined in two separate compartments, and to transport the charge carrier ions selectively for the completion of the circuit during cell operation. In this review, recent studies on non-aqueous redox flow systems are summarized including redox couples, electrolytes, and systems including membranes. A focus is placed on comparison of battery performance in terms of the current and power density through membranes. In addition, we introduce syntheses and characterization of membranes used for non-aqueous RFBs.
T 1 Measurements in the Human Myocardium: The Effects of Magnetization Transfer on the SASHA and (2013)

Purpose: Quantitative mapping of the native T1 of the heart using the modified look-locker inversion recovery (MOLLI) technique provides high quality diagnostic information without requiring contrast agents. Previous work has considered the effects of T2 relaxation on MOLLI T1 measurements, finding that the T1 measured by MOLLI is biased, and that Saturationrecovery single-Shot Acquisition generates a more precise T1. However, despite detailed experiments and simulation the exact relaxation times observed in vivo remain unexplained, but might be due to magnetization transfer (MT). Methods: We used an MT simulation based on the BlochMcConnell equations to evaluate the most common MOLLI and saturation-recovery single-shot acquisition sequence variants. Results: For myocardial tissue we find that the T1 measured by saturation-recovery single-shot acquisition is insensitive to MT and T2, whereas MT reduces the T1 measured by MOLLI (>10%) in addition to the effects due to T2 relaxation. Conclusions: The consequences of this T1 underestimation by MOLLI are relevant. Increases in the actual T1 and T2 and decreases in MT will all result in an increase in T1 measured by MOLLI. Myocardial infarction demonstrates increased native T1 and T2 and decreased MT, indicating that these biases enhance the sensitivity of MOLLI to detect this and possibly other cardiovascular disease states. Magn Reson Med 000:000–000, 2013. V C 2013 Wiley Periodicals, Inc.
Preliminary Analysis of Patients With Progressive Renal Cell Carcinoma Vaccinated With CA9-peptide–Pulsed Mature Dendritic Cells (2006)

Carbonic anhydrase-IXG250/MN (CA9) is a renal cell carcinoma (RCC)-associated antigen ubiquitously expressed in the clear-cell subtype of RCC. Two CA9-derived peptides have been identified defining a cytotoxic T-lymphocyte epitope and human leukocyte antigen (HLA)-DR epitope, able to induce T-cell responses in vitro. A phase I clinical trial was performed with CA9-peptide-loaded dendritic cells (DCs) in patients with progressive, cytokine-refractory metastatic RCC to assess the safety, toxicity, and induction of CA9-specific immunity. Patients with objective progressive metastatic RCC received 5 vaccinations of mature DCs pulsed with the CA9-derived peptides and keyhole limpet hemocyanine (KLH). Peripheral blood was collected at regular intervals, delayed-type hypersensitivity (DTH) was tested at baseline and after the last vaccination, and skin biopsies of positive DTH sites were collected for immunomonitoring purposes. Patients were also monitored for clinical responses. No significant toxicity was observed. All patients developed humoral responses against KLH, and demonstrated DTH conversion. Evaluation of biopsy material suggested an increased influx of T-helper cells. In none of the immunomonitoring assays was evidence for the induction of CA9-peptide-specific immunity observed. No clinical responses were observed. The vaccination of DCs pulsed with KLH and 2 CA9-derived peptides was well tolerated. The lack of induction of CA9-peptide-specific immune responses indicates that this particular vaccine regimen is poor in inducing CA9-peptide-specific immune responses.
FILTER COALESCER DEVICE FOR OIL-WATER SEPARATION (1974)

The development work of a new type, in-depth oil filter- coalescer for the treatment of oily ballast waters is described. Reticulated polyurethane foams emerged as the best filter-coalescer media affording bed fluxes in excess of 10 gpm/ft2 and simple regeneration via squeezing. Extensive separation tests in a 40 gpm unit with a variety of simulated oily ballast have demonstrated that an effluent of less than 30 ppm oil can be produced from an influent containing on the average of up to several thousand ppm oil including oil slugs. Substantial retention of suspended solids was also noted without causing either irreversible clogging of the foam or reduction in the oil separation efficiency.
Respective contributions of Arabidopsis <scp>DCL</scp>2 and <scp>DCL</scp>4 to <scp>RNA</scp> silencing (2014)

Dicer proteins are central to the different mechanisms involving RNA interference. Plants have evolved multiple DICER-LIKE (DCL) copies, thus enabling functional diversification. In Arabidopsis, DCL2 and DCL4 process double-stranded RNA into 22 and 21 nucleotide small interfering (si)RNAs, respectively, and have overlapping functions with regards to virus and transgene silencing. Nonetheless, some studies have reported that dcl2 or dcl4 single mutations are sometimes sufficient to hinder silencing. To better dissect the role of DCL2 and DCL4, we analyzed silencing kinetics and efficiencies using different transgenic systems in single and double mutant backgrounds. The results indicate that DCL2 stimulates transitivity and secondary siRNA production through DCL4 while being sufficient for silencing on its own. Notably, silencing of 35S-driven transgenes functions more efficiently in dcl4 mutants, indicating that DCL4 mostly obscures DCL2 in wild-type plants. Nonetheless, in a dcl4 mutant compromised in phloem-originating silencing, ectopically expressed DCL2 allows restoration of silencing, suggesting that DCL2 is not, or poorly, expressed in phloem. Remarkably, this ectopic DCL2 contribution to phloem-originating silencing is dependent on the activity of RNA-DEPENDENT RNA POLYMERASE6. These results indicate that, despite differences in the silencing activity of their small RNA products, DCL2 and DCL4 mostly act redundantly yet hierarchically when present simultaneously.
The secreted hemolysins of Proteus mirabilis, Proteus vulgaris, and Morganella morganii are genetically related to each other and to the alpha-hemolysin of Escherichia coli (1987)

Secreted hemolysins were extremely common among clinical isolates of Proteus mirabilis, Proteus vulgaris, and Morganella morganii, and hemolytic activity was either cell associated or cell free. Southern hybridization of total DNA from hemolytic isolates to cloned regions of the Escherichia coli alpha-hemolysin (hly) determinant showed clear but incomplete homology between genes encoding production of hemolysins in the four species. One of the two E. coli secretion genes, hlyD, hybridized only with DNA from P. vulgaris and M. morganii, which produced cell-free hemolysis, but not with that from P. mirabilis, which showed only cell-associated activity. Molecular cloning of the genetic determinants of cell-free hemolytic activity from P. vulgaris and M. morganii chromosomal DNA allowed their functional analysis via inactivation with the transposons Tn1000 and Tn5. Both hemolysin determinants were about 7.5 kilobase pairs and comprised contiguous regions directing regulation, synthesis, and specific secretion out of the cell. Transposon mutations which eliminated secretion of the Proteus and Morganella hemolysins could be complemented specifically by the E. coli hemolysin secretion genes hlyB or hlyD. Alignment of the physically and functionally defined hly determinants from P. vulgaris and M. morganii with that of the E. coli alpha-hemolysin confirmed a close genetic relationship but also indicated extensive evolutionary divergence.
Diffractive grating based out-of-plane coupling between silicon nanowire and optical fiber (2009)

A diffractive grating in silicon was demonstrated for near vertical off-chip coupling between Silicon-on-insulator (SOI) photonic nanowire and optical fiber. By simulation, the coupling efficiency of 46% from nanowire to fiber was predicted. Finally, the grating coupler with the efficiency of 25% and 3-dB bandwidth of 45 nm was obtained.
Regulation of asparagine synthetase gene expression by amino acid starvation. (1991)

We have studied the regulation of expression of the asparagine synthetase (AS) gene in ts11 cells, a mutant of BHK hamster cells which encodes a temperature-sensitive AS and therefore does not produce endogenous asparagine at 39.5 degrees C. Incubation of ts11 cells at the nonpermissive temperature drastically increases the level of AS mRNA, and the stimulation of AS mRNA expression is effectively suppressed by the addition of asparagine to the medium. We show here that regulation of AS gene expression involves cis-acting elements which are contained in the mRNA as well as in the 5' genomic region. When a plasmid containing the human AS cDNA under the control of the human AS promoter region was stably transfected into ts11 cells, the expression of human AS RNAs was regulated as that of the endogenous hamster transcripts, indicating that this construct contained all cis elements necessary for regulation. Expression of the AS cDNA in ts11 cells under the control of a constitutive foreign promoter was also regulated by the concentration of asparagine, and this regulation required translation. When we introduced by mutagenesis a number of stop codons in the AS cDNA, the mutant mRNAs with short open reading frames were expressed at low levels that were not increased by asparagine deprivation. Inhibition of protein and RNA synthesis also prevented down-regulation of AS mRNA levels by high concentrations of asparagine. In a parallel series of experiments, we showed that an AS DNA fragment including the promoter and first exon can also regulate RNA expression in response to asparagine concentration. Furthermore, similar increases in the levels of AS RNAs are produced not only by asparagine deprivation in ts11 cells but also by deprivation of human and wild-type BHK cells of leucine, isoleucine, or glutamine. Thus, regulation of AS gene expression is a response to amino acid starvation through mechanisms which appear to involve both changes in RNA stability and change in the rates of transcription initiation or elongation.
Dynamic hierarchical mobility management strategy for mobile IP networks (2004)

One of the major challenges for the wireless network design is the efficient mobility management, which can be addressed globally (macromobility) and locally (micromobility). Mobile Internet protocol (IP) is a commonly accepted standard to address global mobility of mobile hosts (MHs). It requires the MHs to register with the home agents (HAs) whenever their care-of addresses change. However, such registrations may cause excessive signaling traffic and long service delay. To solve this problem, the hierarchical mobile IP (HMIP) protocol was proposed to employ the hierarchy of foreign agents (FAs) and the gateway FAs (GFAs) to localize registration operations. However, the system performance is critically affected by the selection of GFAs and their reliability. In this paper, we introduce a novel dynamic hierarchical mobility management strategy for mobile IP networks, in which different hierarchies are dynamically set up for different users and the signaling burden is evenly distributed among the network. To justify the effectiveness of our proposed scheme, we develop an analytical model to evaluate the signaling cost. Our performance analysis shows that the proposed dynamic hierarchical mobility management strategy can significantly reduce the system signaling cost under various scenarios and the system robustness is greatly enhanced. Our analysis also shows that the new scheme can outperform the Internet Engineering Task Force mobile IP hierarchical registration scheme in terms of the overall signaling cost. The more important contribution is the novel analytical approach in evaluating the performance of mobile IP networks.
Human Dermal Stem/Progenitor Cell-Derived Conditioned Medium Ameliorates Ultraviolet A-Induced Damage of Normal Human Dermal Fibroblasts (2013)

Adult skin stem cells are considered an attractive cell resource for therapeutic potential in aged skin. We previously reported that multipotent human dermal stem/progenitor cells (hDSPCs) can be enriched from (normal human dermal fibroblasts (NHDFs) using collagen type IV. However, the beneficial effects of hDSPCs on aged skin remain to be elucidated. In the present study, we analyzed the growth factors secreted from hDSPCs in conditioned medium (CM) derived from hDSPCs (hDSPC-CM) and found that hDSPCs secreted higher levels of bFGF, IGFBP-1, IGFBP-2, HGF, VEGF and IGF-1 compared with non-hDSPCs. We then investigated whether hDSPC-CM has an effect on ultraviolet A (UVA)-irradiated NHDFs. Real-time RT-PCR analysis revealed that the treatment of UVA-irradiated NHDFs with hDSPC-CM significantly antagonized the UVA-induced up-regulation of the MMP1 and the UVA-induced down-regulation of the collagen types I, IV and V and TIMP1 mRNA expressions. Furthermore, a scratch wound healing assay showed that hDSPC-CM enhanced the migratory properties of UVA-irradiated NHDFs. hDSPC-CM also significantly reduced the number of the early and late apoptotic cell population in UVA-irradiated NHDFs. Taken together, these data suggest that hDSPC-CM can exert some beneficial effects on aged skin and may be used as a therapeutic agent to improve skin regeneration and wound healing.
IPV6 security enhancements still not everything you need (1998)

With all the hype about IPV6 starting to finally come to some levels of fruition, there comes the hype about IPV6 security. Yes, it is true that there are some optional security facilities in IPV6. It is also true that they greatly improve security of a connection, overall, if used. But, before you get too excited or complacent (depending upon your mindset) about the facilities, it's a good idea to know what, exactly, the facilities are and the fact that they will not solve all the security problems that are encountered on IPV6 networks.
POD: Performance Oriented I/O Deduplication for Primary Storage Systems in the Cloud (2014)

Recent studies have shown that moderate to high data redundancy clearly exists in primary storage systems in the Cloud. Our experimental studies reveal that data redundancy exhibits a much higher level of intensity on the I/O path than that on disks due to the relatively high temporal access locality associated with small I/O requests to redundant data. On the other hand, we also observe that directly applying data deduplication to primary storage systems in the Cloud will likely cause space contention in memory and data fragmentation on disks. Based on these observations, we propose a Performance-Oriented I/O Deduplication approach, called POD, rather than a capacity-oriented I/O deduplication approach, represented by iDedup, to improve the I/O performance of primary storage systems in the Cloud without sacrificing capacity savings of the latter. The salient feature of POD is its focus on not only the capacity-sensitive large writes and files, as in iDedup, but also the performance-sensitive while capacity-insensitive small writes and files. The experiments conducted on our lightweight prototype implementation of POD show that POD significantly outperforms iDedup in the I/O performance measure by up to 87.9% with an average of 58.8%. Moreover, our evaluation results also show that POD achieves comparable or better capacity savings than iDedup.
Development of Novel Acidizing Inhibitors for Carbon Steel Corrosion in 15% Boiling Hydrochloric Acid (2008)

The inhibitive action of 1-cinnamylidine-3-thiocarbohydrazide (CTCH) and 1,1ʹ-dicinnamylidine-3-thiocarbohydrazide (DCTCH) against the corrosion of carbon steel in 15% hydrochloric acid (HCl) was investigated using nonelectrochemical and electrochemical techniques. Potentiodynamic polarization studies revealed that the compounds were mixed-type inhibitors and exhibited more than 97% inhibition efficiency at 1,500 ppm of inhibitor concentration. The effect of temperature on the corrosion behavior of carbon steel in 15% HCl with 1,500 ppm of inhibitors was studied in the temperature range from 30°C to 110°C. The surface coverage (θ) increased linearly with the logarithm of the inhibitor concentration fitting a Temkin adsorption isotherm. Thermodynamic parameters including the free energy of adsorption, activation energy, enthalpy, entropy, and heat of adsorption were also calculated. The inhibitors reduced the hydrogen permeation current effectively through the steel surface. The protective film formed on the metal surface by the adsorption of organic compounds was confirmed using Fourier transform infrared (FTIR), ultraviolet (UV)-visible reflectance, and scanning electron microscopy (SEM) studies.
Microhardness and Elastic Moduli of Si‐Y‐A1‐O‐N Glasses (1982)

Glasses containing up to 15 at.% N were prepared and tested. The glasses were translucent to transparent, very hard, and had elastic moduli as high as 186 GPa.
<title>Physical properties and concepts for applications of attenuation-based fiber optic dosimeters for medical instrumentation</title> (1992)

The dependence of the losses induced by ionizing radiation on the ambient conditions is studied for lead glass fibers in the parameter range of relevance for medical technology. On the basis of these results, a concept is developed for a fiber-optic dosimeter system and initial measuring results are communicated using an experimental arrangement of this type of dosimeter system under application-oriented conditions. Some applications of this system in radiotherapy are shown which are not feasible with conventional dosimeters at all, or only in exceptional cases, and which can contribute to safe handling and more effective use in radiotherapy.
Two-Phase Survivable Thermal Management - Heat Acquisition and Transport Components (1992)

<div class="htmlview paragraph">This paper describes advanced heat acquisition and transport components developed and tested as part of the Two-Phase Survivable Thermal Management (TSTM) Program. The components are: a pumped heat pipe coldplate capable of removing very high-flux waste heat loads with a minimum temperature drop; and a thermal transport system designed to transport large quantities of waste heat over large distances with a long life and low power consumption. These components are intended for use in an advanced thermal control system which removes waste heat from high-power spacecraft.</div> <div class="htmlview paragraph">For the heat acquisition component, a successful design development phase was completed, resulting in a producible design which met program goals. This design was subjected to extensive tests to demonstrate performance under a wide variety of conditions. The component was found to perform in a predictable manner. Measured overall component thermal conductance was 4.0 W/cm<sup>2</sup>/°C for fluxes up to 60 W/cm<sup>2</sup>. The device was operated at steady-state heat fluxes up to 100 W/cm<sup>2</sup>, and was subjected to brief pulse loads up to 200 W/cm<sup>2</sup>.</div> <div class="htmlview paragraph">For the heat transport component, existing pump and valve designs were substantially modified and a life test using ammonia working fluid was initiated. Design modifications were based on reliability requirements and prior ammonia loop experience. An ammonia life test flow loop was designed and constructed for the life tests. The ongoing tests have uncovered two design deficiencies in the centrifugal pump, which resulted in bearing degradation and failure. Design modifications were implemented, tests were resumed and the modified pump has been continuously operated for over 7500 hours without problems. The regulating valve has been continuously exposed to ammonia for over eighteen months and operated for over 7500 hours without any failures.</div>
A new current measuring principle for power electronic applications (2003)

A new isolated current measurement principle named HOKA is presented. A current probe based on this principle has been realized. It was designed for a current rating of 200 A. The probe incorporates two different sensors: a Hall sensor and an air coil. DC currents of 200 A as well as transients with a di/dt of 2.5 kA//spl mu/s have been measured with a relative error of 5%.
Pressure transducer with Au-Ni thin-film strain gauges (1993)

The behavior of a pressure transducer with Au-Ni (89:11) film as strain gauges has been studied. The effects of postdeposition heat treatment on the resistance of the thin-film strain gauges and hence the output performance of the pressure transducer are discussed. The effect of a repeated number of pressure cycles carried out over a period of eight months has also been reported. The maximum nonlinearity and the hysteresis is improved from 0.92% FSO to 0.06% FSO after 1000 pressure cycles. The output behavior of the pressure transducer with temperature has also been studied.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
In-plane reversal mechanisms in circular Co dots (2002)

The reversal process of polycristalline circular Co dots is investigated for dot sizes for which the vortex state corresponds to the ground state configuration. Using magneto-optic Kerr magnetometry and magnetic force microscopy imaging, it is found that during the reversal of the magnetization, the system does not necessarily pass through its ground state configuration. For large dot diameters and thickness, the reversal occurs via nucleation, propagation, and expulsion of a single vortex, whereas for a dot thickness below 20 nm the reversal process may occur by a coherent rotation of the quasi-single-domain configuration. Furthermore, a double-vortex state formation has been evidenced for 1000-nm-large dots.