gebhart/patrepeval huggingface dataset:
A Natural Pixel Decomposition for Two-Dimensional Image Reconstruction (1981)

In two-dimensional image reconstruction from line integrals using maximum likelihood, Bayesian, or minimum variance algorithms, the x-y plane on which the object estimate is defined is decomposed into nonoverlapping regions, or "pixels." This decomposition of an otherwise continuous structure results in significant errors, or model noise, which can exceed the effects of the fundamental measurement noise.
What is the optimum leaf width of a multileaf collimator? (2000)

With the help of the sampling theory and, more generally, the theory of linear systems, one can find a general answer to the question about the optimum leaf width of a multileaf collimator from a physical point of view. It is important to distinguish between the sampling distance and the leaf width. The sampling distance is more critical than the leaf width. The leaf width can be up to twice as large as the sampling width. Furthermore, the derived sampling distance can be used to select the optimum resolution of both the fluence and the dose grid in dose calculation and inverse planning algorithms.
A “Closed” Medical Intensive Care Unit (MICU) Improves Resource Utilization When Compared with an “Open” MICU (1998)

We hypothesized that a "closed" intensive care unit (ICU) was more efficient that an "open" one. ICU admissions were retrospectively analyzed before and after ICU closure at one hospital; prospective analysis in that ICU with an open ICU nearby was done. Illness severity was gauged by the Mortality Prediction Model (MPM0). Outcomes included mortality, ICU length of stay (LOS), hospital LOS, and mechanical ventilation (MV). There were no differences in age, MPM0, and use of MV. ICU and hospital LOS were lower when "closed" (ICU LOS: prospective 6.1 versus 12.6 d, p < 0.0001; retrospective 6.1 versus 9.3 d, p < 0.05; hospital LOS: prospective 19.2 versus 33.2 d, p < 0.008; retrospective 22.2 versus 31.2 d, p < 0.02). Days on MV were lower when "closed" (prospective 2.3 versus 8.5 d, p < 0.0005; retrospective 3.3 versus 6.4 d, p < 0.05). Pooled data revealed the following: MV predicted ICU LOS; ICU organization and MPM0 predicted days on MV; MV and ICU organization predicted hospital LOS; mortality predictors were open ICU (odds ratio [OR] 1.5, p < 0.04), MPM0 (OR 1.16 for MPM0 increase 0.1, p < 0.002), and MV (OR 2.43, p < 0.0001). We conclude that patient care is more efficient with a closed ICU, and that mortality is not adversely affected.
Interaction between water and poly(vinylpyrrolidone) containing polyethylene glycol (1999)

Information on the interaction between water and polymers is indispensable for manufacturing solid dispersion of a drug by hot-melt extrusion because this interaction affects various properties of the water-polymer mixtures, such as their viscoelastic properties. In this study, poly(vinylpyrrolidone) K30 (PVP) containing 0%, 10%, and 20% poly(ethylene glycol) 400 (PEG) was used as model amorphous polymers. The interaction of water with these polymers was assessed by the evaluation of the glass transition temperature (Tg), the point on the isotherm corresponding to the weight of sorbed water required to form a complete monolayer on the solid surface (apparent Wm), and the maximal amount of nonfreezing water, which were measured by differential scanning calorimetry and water sorption isotherms. In all of the systems with a water content below a certain water fraction (0.1 for PVP, 0.12 for PVP-PEG 10%, and 0.16 for PVP-PEG 20%), the Tg values were successfully predicted using theoretical equations, whereas the experimental Tg values were higher than predicted for those with a water content above these water fraction levels. In addition, these values of water fraction are similar to the apparent W(m) values determined using the Guggenheim-Anderson-DeBoer (GAB) equation (0.110, 0.117, and 0.147 weight fraction of water for PVP, PVP-PEG 10%, and PVP-PEG 20%, respectively). Nonfreezing water is detected above 0.47, 0.49, and 0.51 weight fraction of water for PVP, PVP-PEG 10%, and PVP-PEG 20%, respectively. Miscibility between water and PVP or PVP-PEG seems to change according to the water content in the system. All parameters increase with the concentration of PEG in the sample. This may be explained by the fact that PEG has a larger number of polymer repeating units, which may therefore interact with water more than PVP.
Quantitative Liver Function Analysis: Volumetric T1 Mapping with Fast Multisection B<sub>1</sub>Inhomogeneity Correction in Hepatocyte-specific Contrast-enhanced Liver MR Imaging (2016)

Purpose To determine whether B<sub>1</sub> inhomogeneity-corrected volumetric T1 maps of gadoxetic acid-enhanced liver magnetic resonance (MR) imaging are able to demonstrate global liver function and functional heterogeneity in patients with cirrhosis and to investigate their relationship with the development of hepatic insufficiency and decompensation. Materials and Methods This institutional review board-approved retrospective study with waiver of informed consent included 234 consecutive patients who underwent gadoxetic acid-enhanced liver MR imaging, including B<sub>1</sub> inhomogeneity-corrected volumetric T1 mapping. For all patients, T1 relaxation times of the liver and liver volumes were measured on T1 maps. Liver T1 and functional liver volume-to-weight ratio (liver volume divided by liver T1 and the patient's weight) were compared between Child-Pugh class A and class B cirrhosis. Associations between serum markers, MR parameters, hepatic insufficiency, and decompensation were investigated by using Cox proportional hazards analysis. Results Patients with Child-Pugh class B disease showed significantly longer liver T1 (548.2 msec ± 257.7 vs 372.2 msec ± 77.5, P < .0001) and lower kurtosis of liver T1 (29.1 ± 39.6 vs 43.9 ± 64.9, P = .016) than patients with Child-Pugh class A disease. Prolonged liver T1 (≥462 msec) (hazard ratio [HR], 5.9; 95% confidence interval [CI]: 1.1, 62.8) and an albumin level of less than 3.5 g/dL (HR, 20.7; 95% CI: 3.9, 221.9) were independently associated with the development of hepatic insufficiency. Functional liver volume-to-weight ratio was associated with the development of hepatic decompensation in patients with Child-Pugh class A disease (HR, 0.03; 95% CI: 0.004, 0.23). Conclusion B<sub>1</sub> inhomogeneity-corrected volumetric T1 mapping provided information on global liver function and demonstrated functional heterogeneity. In addition, prolonged liver T1 (≥462 msec) was associated with the development of hepatic insufficiency, and functional liver volume-to-weight ratio was negatively related with the development of decompensation in compensated cirrhosis. <sup>©</sup> RSNA, 2016 Online supplemental material is available for this article.
<title>Gain characteristics of a ytterbium-doped fiber amplifier at 1064nm</title> (2006)

Because an ytterbium-doped fiber amplifier has broad-gain bandwidth, high output power, and excellent power conversion efficiency, it has attracted much attention. Based on two-level model, the gain and propagation characteristics of Yb-doped fiber amplifier at 1064nm by dual-wavelength pumping (910nm and 975nm) were analyzed after introducing the overlapping factors and ignoring the effect of ASE and the fiber loss. In order to compare, other two pumping schemes were discussed, namely, 910nm pumping and 975nm pumping respectively. The differences between the Yb- and Nd-doped fibers for amplifying the light of 1064nm were also discussed.
Phosphorylation of tyrosine 256 facilitates nuclear import of atypical protein kinase C (2002)

Herein, we employed a combined approach of molecular modeling and site-directed mutagenesis to address the role of tyrosine phosphorylation in transport of atypical protein kinase C (aPKC) into the nucleus. Computer modeling of the three-dimensional structure of the aPKC catalytic core, reveals that tyrosine 256 (Tyr256) is located at the lip of the activation loop and is conserved among members of the aPKC family, ι/λ and ζ. Based on these findings, we examined whether tyrosine phosphorylation of aPKC on the activation lip may facilitate nuclear import. An antiserum was generated that selectively recognizes the phosphorylated Tyr256 residue in aPKC. By isolating nuclei of PC12 cells and immunoprecipitating aPKC with Ab-PY256, we observed that Tyr256 is rapidly phosphorylated upon NGF treatment prior to entry of aPKC into the nucleus. aPKC was observed to exclusively bind to importin-β. The interaction between importin-β and aPKC was enhanced upon tyrosine phosphorylation of aPKC and binding was abrogated when Tyr256 was mutated to phenylalanine. We propose that phosphorylation of aPKC at Tyr256 induces a conformation, whereby, the arginine-rich NLS is exposed, which then binds importin-β leading to import of aPKC into the nucleus. Altogether, these findings document a novel role for the tyrosine phosphorylation in regulating import of atypical PKC into the nucleus. J. Cell. Biochem. 85: 42–53, 2002. © 2002 Wiley-Liss, Inc.
Ultrastrong, Foldable, and Highly Conductive Carbon Nanotube Film (2012)

Preparation of strong, flexible, and multifunctional carbon-based films has attracted considerable interest not only in fundamental research areas but also for industrial applications. We report a binder-free, ultrastrong, and foldable carbon nanotube (CNT) film using aligned few-walled nanotube sheets drawn from spinnable nanotube arrays. The film exhibits tensile strengths up to ∼2 GPa and a Young's modulus up to ∼90 GPa, which is markedly superior to other types of carbon-based films reported, including commercial graphite foils, buckypapers, and graphene-related papers. The film can bear severe bending (even being folded) and shows good structure integrity and negligible change in electric conductivity. The unique structure of the CNT film (good nanotube alignment, high packing density) provides the film with direct and efficient transport paths for electricity. As a flexible charge collector, it favors a magnesium oxide coating to exhibit high charge/discharge rate stability and an excellent electrochemical capacitance close to its theoretical value.
Application of Support Vector Machine to the classification of volcanic tremor at Etna, Italy (2006)

We applied an automatic pattern recognition technique, known as Support Vector Machine (SVM), to classify volcanic tremor data recorded during different states of activity at Etna volcano, Italy. The seismic signal was recorded at a station deployed 6 km southeast of the summit craters from 1 July to 15 August, 2001, a time span encompassing episodes of lava fountains and a 23 day‐long effusive activity. Trained by a supervised learning algorithm, the classifier learned to recognize patterns belonging to four classes, i.e., pre‐eruptive, lava fountains, eruptive, and post‐eruptive. Training and test of the classifier were carried out using 425 spectrogram‐based feature vectors. Following cross‐validation with a random subsampling strategy, SVM correctly classified 94.7 ± 2.4% of the data. The performance was confirmed by a leave‐one‐out strategy, with 401 matches out of 425 patterns. Misclassifications highlighted intrinsic fuzziness of class memberships of the signals, particularly during transitional phases.
Isomerization-crystallization method in optical resolution. (1986)

In recent years, synthetic method by the combination of isomerization and crystallization is studied intensively, especially in the practical optical resolution. In this paper, this isomerization-crystallization method is introduced from a point of view of practical organic synthesis. A number of examples of this isomerization-crystallization method in optical resolution, many of which were often reported as the example of second-order asymmetric transformation phenomena, are classified into following two groups, and reviewed.(1) Epimerization-crystallization method.(2) Racemization-preferential crystallization method.The potentialities and difficulities of each method are also discussed. The compounds resolved by this methods are α-amino acid derivatives, cyanohydrin derivatives, α-aromatic carboxylic acid esters, and so on.
Strategies for peace education integration in ECOWAS member states' tertiary school curricula (2008)

Much has been invested by the Economic Community of West African States (ECOWAS), African Union (AU), United Nations (UN) and other members of the international community in making, keeping and building peace in the West African subregion since the early 1990s. The outcomes of all these interventions are encouraging. Whilst they may not have been able to stand the test of time, institutions of higher learning in West Africa have started to offer degrees in peace and security studies in an attempt to increase the number of professional peace workers in the subregion. Up until now, more than 90% of the indigenous peace workers were trained in workshops organised by the international agencies doing peace work in the region. The knowledge provided to the trainees was limited in scope, having been dictated by the fixed mandate of the organisations that provided the training.
Improved Bioavailability of Dietary Phenolic Acids in Whole Grain Barley and Oat Groat following Fermentation with Probiotic Lactobacillus acidophilus, Lactobacillus johnsonii, and Lactobacillus reuteri (2012)

The aim of this study was to improve the bioavailability of the dietary phenolic acids in flours from whole grain barley and oat groat following fermentation with lactic acid bacteria (LAB) exhibiting high feruloyl esterase activity (FAE). The highest increase of free phenolic acids was observed after fermentation with three probiotic strains, Lactobacillus johnsonii LA1, Lactobacillus reuteri SD2112, and Lactobacillus acidophilus LA-5, with maximum increases from 2.55 to 69.91 μg g(-1) DM and from 4.13 to 109.42 μg g(-1) DM in whole grain barley and oat groat, respectively. Interestingly, higher amounts of bound phenolic acids were detected after both water treatment and LAB fermentation in whole grain barley, indicating higher bioaccessibility, whereas some decrease was detected in oat groat. To conclude, cereal fermentation with specific probiotic strains can lead to significant increase of free phenolic acids, thereby improving their bioavailability.
Rapid Differentiation of “ <i>Mycobacterium canettii</i> ” from Other <i>Mycobacterium tuberculosis</i> Complex Organisms by PCR-Restriction Analysis of the <i>hsp65</i> Gene (2001)

A total of 102 isolates of the Mycobacterium tuberculosis complex, including available "M. canettii" isolates, were studied by PCR-restriction analysis of a 441-bp fragment of the hsp65 gene. PRA upon HhaI enzyme digestion (GCGC) allowed easy differentiation of "M. canettii" from other members of the M. tuberculosis complex (three bands of 260, 105, and 60 bp for "M. canetti," compared to four bands of 185, 105, 75, and 60 bp for other members of the M. tuberculosis complex). Sequencing of the 441-bp hsp65 fragment of "M. canettii" isolates showed the disappearance of an HhaI site at position 235 due to a C-to-T transition that corresponded to position 631 of the homologous hsp65 gene of M. tuberculosis H37Rv. Considering that "M. canettii" may also exist as a stable rough morphotype, we suggest that the true number of "M. canettii" isolates may be underestimated in clinical microbiology laboratories.
The effect of simvastatin on the proteome of detergent‐resistant membrane domains: Decreases of specific proteins previously related to cytoskeleton regulation, calcium homeostasis and cell fate (2010)

Cell death induced by over-activation of glutamate receptors occurs in different neuropathologies. Cholesterol depletors protect from neurotoxic over-activation of glutamate receptors, and we have recently reported that this neuroprotection is associated with a reduction of the N-methyl-D-aspartate subtype of glutamate receptors in detergent-resistant membrane domains (DRM). In the present study we used comparative proteomics to further identify which proteins, besides the N-methyl-D-aspartate receptor, change its percentage of association to DRM after treatment of neurons with simvastatin. We detected 338 spots in neuronal DRM subjected to 2-DE; eleven of these spots changed its intensity after treatment with simvastatin. All 11 differential spots showed reduced intensity in simvastatin-treated samples and were identified as adipocyte plasma membrane associated protein, enolase, calretinin, coronin 1a, f-actin capping protein alpha1, f-actin capping protein alpha2, heat shock cognate protein 71, malate dehydrogenase, n-myc downregulated gene 1, prohibitin 2, Rab GDP dissociation inhibitor, translationally controlled tumor protein and voltage dependent anion selective channel protein 1. The proteins tested colocalized with the lipid raft marker caveolin-1. Interestingly, the proteins we have identified in the present study had been previously reported to play a role in cell fate and, thus, they might represent novel targets for neuroprotection.
On the Origin of Excess Loss in Highly GeO&lt;tex&gt;$_2$&lt;/tex&gt;-Doped Single-Mode MCVD Fibers (2004)

Index profile grading and elimination of the central dip have yielded the lowest loss ever reported for modified chemical vapor deposition-made highly GeO/sub 2/-doped single-mode fibers (1.33 dB/km at 1550 nm for /spl Delta/=2.9%). Investigation of the angular distribution of scattering has shown that much of the optical loss in such fibers is due to anomalous scattering. This scattering arises in the region of the central dip in the refractive index profile and at the core-cladding interface.
Video error concealment using decoder motion vector estimation (2002)

Audio-visual and other multimedia services are seen as important sources of traffic for future wireless networks. An important characteristic of such networks is that they introduce a significant number of errors into the transmitted digital bitstream. For services' such as video, these errors can have the effect of degrading the quality of the received service to the point where it is unusable. We introduce a technique that allows the concealment of the impact of these errors. Our work is based on MPEG 2 encoded video (although our scheme would work equally well with other standards) to be transmitted over a wireless network whose data structures are similar to those of asynchronous transfer mode (ATM). Our simulations include the impact of the MPEG 2 Systems Layer and cover cell loss rates up to 5%.
Inverted Organic Photovoltaic Cells with Solution-Processed Zinc Oxide as Electron Collecting Layer (2011)

In this work, inverted polymer:fullerene organic photovoltaic (OPV) cells with solution-processed zinc oxide (ZnO) as the electron collecting layer are investigated. ZnO films are prepared simply by the spin-casting of a zinc acetate dehydrate precursor solution, followed by sintering under ambient conditions. The performance of the fabricated inverted OPV cells shows a clear dependence on precursor concentration and sintering conditions. With the ZnO film derived from a sol–gel concentration of 0.1 M and sintered at 350 °C for 10 min, the inverted OPV cell shows optimum performance.
Hazard ranking system evaluation of CERCLA inactive waste sites at Hanford: Volume 3: Unplanned-release sites (HISS data base) (1988)

The purpose of this report is to formally document the assessment activities at the US Department of Energy (DOE) Hanford Site. These activities were carried out pursuant to the DOE orders that address the Comprehensive Environmental Response, and Liability Act (CERCLA) Program for the cleanup of inactive waste sites. The DOE orders incorporate the US Environmental Protection Agency methodology, which is based on the Superfund Amendments and Reauthorization Act of 1986. This methodology includes:PA/SI, remedial investigation/feasibility study, record of decision, design and implementation or remedial action, operation and monitoring, and verification monitoring. Volume 1 of this report discusses the CERCLA inactive waste-site evaluation process, assumptions, and results of the Hazard Ranking System methodology employed. Volume 2 presents the data on the individual CERCLA engineered-facility sites at Hanford, as contained in the Hanford Inactive Site Surveillance (HISS) Data Base. Volume 3 presents the data on the individual CERCLA unplanned-release sites at Hanford, as contained in the HISS Data Base. 13 figs.
Pulmonary endocrine cells in pulmonary arterial disease. (1989)

Pulmonary endocrine cells containing bombesin or calcitonin have been identified in human lungs by the peroxidase-antiperoxidase method. The numbers of such cells were greatly increased in patients with plexogenic pulmonary arteriopathy whether that condition was associated with primary pulmonary hypertension or with pulmonary hypertension from intracardiac shunts. The numbers of endocrine cells tended to be increased, but to a lesser extent in patients with pulmonary hypertension and medial hypertrophy of the muscular pulmonary arteries in the absence of plexogenic arteriopathy. Increased numbers of endocrine cells comprised both greater numbers of solitary cells and a pronounced clustering, often of a disorganized nature.
Characterization and photoluminescence properties of diglycidyl methacrylic resin doped with the Eu<sup>3+</sup>–β‐diketonate complex (2006)

Abstract Triaquatris(acetyl acetonate)europium(III) [Eu(acac) 3 ] at 1, 5, 10, and 15% was doped in diglycidyl methacrylic (DGMA) resin, and their luminescent properties in the solid state are reported. These systems were characterized with elemental analysis, thermogravimetric analysis (TGA), differential scanning calorimetry (DSC), and Fourier transform infrared spectroscopy. On the basis of TGA data, the thermal stability of the DGMA/Eu(acac) 3 x % system was similar to that of the polymer, except at the highest concentration (15%). The DSC results indicated that the new systems were chemically stable and underwent the cure process before decomposition. The emission spectra of the Eu 3+ /acetyl acetonate complex doped in DGMA, recorded at 298 and 77 K, exhibited the characteristic bands arising from the 5 D 0 → 7 F J transitions ( J = 0–4). The luminescence intensity decreased with an increasing precursor concentration in the doped polymer. The system doped at a low concentration (1% Eu 3+ complex) presented more luminescence efficiency than those doped at 5, 10, and 15%. © 2006 Wiley Periodicals, Inc. J Appl Polym Sci 100: 406–412, 2006