gebhart/patrepeval huggingface dataset:
A Spectral Shaper Based Two-Tap RF Self-Interference Canceller for Full-Duplex Radios (2019)

A simple and effective two-tap RF Self-Interference Cancellation (SIC) circuit is proposed for in-band Full-Duplex radio. Conventional techniques deal with phase-based RF cancellation which inherently results in non-flat spectrum (especially for wideband signals). Any conventional second cancellation stage cannot significantly improve SIC in the RF domain due to this non-flat Residual RF spectrum. This work proposes a novel "Spectral shaper" that improves SIC by 16dB on a 20MHz bandwidth RF signal, validated through experimental measurements on a discrete prototype. This model, in conjunction with a circulator, offers a total of 62dB RF SIC, and is implemented here using readily available off-the-shelf components.
Utility-Based Hybrid Memory Management (2017)

While the memory footprints of cloud and HPC applications continue to increase, fundamental issues with DRAM scaling are likely to prevent traditional main memory systems, composed of monolithic DRAM, from greatly growing in capacity. Hybrid memory systems can mitigate the scaling limitations of monolithic DRAM by pairing together multiple memory technologies (e.g., different types of DRAM, or DRAM and non-volatile memory) at the same level of the memory hierarchy. The goal of a hybrid main memory is to combine the different advantages of the multiple memory types in a cost-effective manner while avoiding the disadvantages of each technology. Memory pages are placed in and migrated between the different memories within a hybrid memory system, based on the properties of each page. It is important to make intelligent page management (i.e., placement and migration) decisions, as they can significantly affect system performance.In this paper, we propose utility-based hybrid memory management (UH-MEM), a new page management mechanism for various hybrid memories, that systematically estimates the utility (i.e., the system performance benefit) of migrating a page between different memory types, and uses this information to guide data placement. UH-MEM operates in two steps. First, it estimates how much a single application would benefit from migrating one of its pages to a different type of memory, by comprehensively considering access frequency, row buffer locality, and memory-level parallelism. Second, it translates the estimated benefit of a single application to an estimate of the overall system performance benefit from such a migration.We evaluate the effectiveness of UH-MEM with various types of hybrid memories, and show that it significantly improves system performance on each of these hybrid memories. For a memory system with DRAM and non-volatile memory, UH-MEM improves performance by 14% on average (and up to 26%) compared to the best of three evaluated state-of-the-art mechanisms across a large number of data-intensive workloads.
Monosodium [1-hydroxy-2-(1<i>H</i>-imidazol-3-ium-4-yl)ethane-1,1-diyl]bis(phosphonate) tetrahydrate (monosodium isozoledronate) (2002)

The title compound, Na(+).C(5)H(9)N(2)O(7)P(2)(-).4H(2)O, is an isomer of zoledronate, a potent bone antiresorptive bisphosphonate drug having significant activity against several parasitic protozoa. The crystal structure of isozoledronate consists of bisphosphonate dimers coordinated by two Na(+) ions. The dimers are held together through an extensive hydrogen-bonding network. The crystals exhibit non-merohedral twinning that roughly superimposes the a and b axes, and inverts the c axis.
Safety and efficacy of clonidine and clonidine extended-release in the treatment of children and adolescents with attention deficit and hyperactivity disorders (2011)

Clonidine has been used off-label in children and adolescents with attention deficit and hyperactivity disorders (ADHD) with or without comorbidities. Clonidine extended-release was recently approved by the US Food and Drug Administration for ADHD in children. This review evaluates the efficacy and safety of clonidine extended-release and clonidine in children and adolescents with ADHD. A search of the Medline database and clinical trials register from 1996-2011 yielded ten clinical trials for critical evaluation of efficacy and safety. Eight of the ten trials reviewed were double-blinded and placebo-controlled. Nine of the ten trials utilized multiple outcome measures. Both clonidine extended-release and clonidine, as monotherapy or adjunctive therapy, were reported to be efficacious in treating ADHD symptoms in children and adolescents with or without comorbid disorders in nine of the ten clinical trials. One study showed clonidine to be ineffective in improving performance of a single task, at a specific point in time, in a small number of subjects. All of the studies that evaluated safety reported clonidine and clonidine extended-release to be well tolerated. The side effects of clonidine included somnolence, fatigue, headache, bradycardia, hypotension, and clinically insignificant electrocardiographic changes. However, there are historical anecdotal reports of serious cardiac side effects, including death in cases with other risk factors. None of the studies compared clonidine extended-release with clonidine in subjects with ADHD. Therefore, it is not clear whether clonidine extended-release is advantageous over clonidine, with regard to either efficacy or safety. It is equally unclear whether clonidine or clonidine extended-release is more efficacious in treating ADHD in subjects with comorbid disorders than in those without comorbidities. All the studies reviewed had limitations in their designs and methods. Clonidine and clonidine extended-release could be efficacious and safe for the treatment of ADHD both as monotherapy and as adjunctive therapy with stimulant medications in selected patients. There is a need for clinical trials to determine the long-term efficacy and safety of treatment with clonidine and clonidine extended-release in patients with ADHD.
Selection and Breeding of King Oyster Mushroom (2001)

Three strains of the king oyster mushroom, Pleurotus eryngil (DC.: Fr.) Quel., were grown with bottle cultivation system for the evaluation of commercial production. They were the strains ATCC 36047, ATCC 90212 and Holland 150. One of them, i.e. the strain ATCC 36047, showed a high potentiality for commercial production. This strain produced medium to large fruiting bodies with an excellent feature, a firm and fine texture and a long shelf life, while the strain Holland 150 fructified fast and mostly produced large fruiting bodies with a good feature, a soft and fine texture as well as a short shelf life. The latter has a higher biological efficiency than the strain ATCC 36047 did, but it produced many warts on cap surfaces during high RH. In order to obtain a highly productive strain which can produce high quality fruit bodies, monokaryons from the strain ATCC 36047 and Holland 150 were isolated and their mating factors were also determined. Crossing between the monokaryons derived from the two strains and screening of the hybrids thus obtained were conducted. Four highly productive hybrids, i.e. B112, B012, B030 and B011, were obtained, The hybrid B112 produced large fruit bodies with a small cap, an equal to fusiform stipe, a medium soft and fine texture, The hybrid B012 produced stout fruit bodies with a prominent eccentric or lateral stipe and a fan-shaped cap of which surface produced warts during a high humid condition. Its stipe was equal and solid, and consisted of a white and very fine texture. The hybrid B030 produced slender fruit bodies with a medium size, and with a round cap, an equal and solid stipe. This hybrid was inclined to produce many small fruit bodies when the humidity of the cropping room was not properly controlled during cultivation. The hybrid B011 was inclined to produce stout fruit bodies with a large cap and a white and solid stipe. These productive hybrids of the fungus took 54.4 to 60 days from inoculation to the end of crop and they reacted differently to the composition of substrate in the aspect of productivity.
4-[<sup>18</sup>F]Fluoroglutamic Acid (BAY 85-8050), a New Amino Acid Radiotracer for PET Imaging of Tumors: Synthesis and in Vitro Characterization (2010)

There is a high demand for tumor specific PET tracers in oncology imaging. Besides glucose, certain amino acids also serve as energy sources and anabolic precursors for tumors. Therefore, (18)F-labeled amino acids are interesting probes for tumor specific PET imaging. As glutamine and glutamate play a key role in the adapted intermediary metabolism of tumors, the radiosynthesis of 4-[(18)F]fluoro l-glutamic acid (BAY 85-8050) as a new specific PET tracer was established. Cell-uptake studies revealed specific tumor cell accumulation.
A single chip Li-Ion battery protection IC with low standby mode auto release (2014)

A fully integrated cost-effective and low-power single chip Lithium-Ion (Li-Ion) battery protection IC (BPIC) is proposed for portable devices. The control unit of the battery protection system and the MOSFET switches are integrated in a single package to prevent overcharge, overdischarge, and overcurrent of the Li-Ion battery. The BPIC supports low power standby mode and a new auto release function (ARF) is adopted for being released from the standby mode. The proposed BPIC is implemented in a 0.18-μm CMOS process and the chip size is 750×610 μm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . It dissipates 3.0uA, while it consumes only 400nA at standby mode.
A New Lignan and Four New Lignan Glycosides from <i>Mananthes patentiflora</i> (2006)

Abstract A new lignan, 5‐hydroxyjusticidin A (= 9‐(1,3‐benzodioxol‐5‐yl)‐5‐hydroxy‐4,6,7‐trimethoxynaphtho[2,3‐ c ]furan‐1(3 H )‐one; 1 ), and four new diphyllin‐type lignan glycosides, mananthosides C–F ( 2 – 5 ), containing glucosyl (Glc), arabinosyl (Ara), galactosyl (Gal), and/or apiosyl residues, have been isolated from Mananthes patentiflora , together with five known compounds. Their structures and configurations were elucidated by in‐depth 1D‐ and 2D‐NMR experiments, as well as MS analysis.
A Dynamic Retargettable Multi-Protocol RFID Reader/Writer (2007)

In this paper, we propose a novel RFID reader/writer architecture that dynamically retargets various protocols of RFID by changing configuration software. The proposed architecture is not software defined radio, but parameterized hardware that is specialized in RFID protocols. This architecture consumes lower power than that of software defined radio, because the proposed architecture does not require high performance CPUs. In experiments, we have designed a prototype that can read RFID tags: ISO 15693, ISO 18092 (NFCIP-1), and ISO 18000-4. From experimental results, we showed the prototype read tag IDs which include several kinds of RFIDs. Power consumption of this was also reduced by one-third or less, compared with that of others.
De novo initiation of specific cell-mediated immune responsiveness in chickens by transfer factor (specific immunity inducer) obtained from bovine colostrum and milk. (1988)

Transfer factors (TF) were prepared from colostrum and milk of bovines previously immunized with antigens obtained from Coccidioides immitis, infectious bovine rhinotracheitis virus, or from the viral agents responsible for avian Newcastle disease, laryngotracheitis disease or infectious bursal disease. The ability of bovine TF to transfer specific cell-mediated immune responsiveness to a markedly xenogenic species was studied using specific pathogen free (SPF) and standard commercial (SC) chickens as model recipients. Cell-mediated immune responsiveness was documented using one or more of the following for each antigen (organism) studied: (a) an in vitro chicken leukocyte (heterophil) migration inhibition assay; (b) delayed-wattle reactivity; or (c) protection from clinical disease. Chicken TFs obtained from spleens of immune donors were evaluated in parallel to bovine TF's in selected comparative studies. Bovine TF also referred to as specific immunity inducer (SII), and chicken TF were found to initiate antigen-specific cell-mediated immunity de novo in previously non-immune SPF chickens as well as in SC chickens despite the presence of maternally acquired humoral antibody which may serve as a "barrier" to immunization of SC chickens when commercially available vaccines are administered by parenteral routes. Bovine TF's specific for laryngotracheitis virus or infectious bursal disease virus afforded protection equal to that found for commercially available vaccines. Bovine TF's action was rapid (less than a day) and of relatively long duration at least 35 days.
Prostate-specific antigen (PSA) in women. (1999)

Prostate-specific antigen (PSA) is a valuable tumor marker for prostate cancer. It was believed that PSA was produced exclusively by the epithelial cells of the prostate gland, but a large body of evidence demonstrates that PSA is not a prostate-specific molecule. PSA has been shown to be expressed in many forms of female tissues. The breast is a major female organ able to produce PSA. PSA is detected in both normal and abnormal breast tissues, as well as in various breast fluids including milk, nipple aspirate, and cyst fluid. Androgens and progesterones, via their receptors, regulate the production of PSA in breast tissue. Clinical studies demonstrate that PSA in breast cancer is associated with the expression of estrogen receptor and progesterone receptor. Women with PSA-positive breast cancer have better disease-free survival as well as overall survival than those with PSA-negative breast cancer. PSA levels in nipple aspirate fluid may be indicative of breast cancer risk. High concentrations of PSA are found in amniotic fluid and the levels change with gestational age. Pregnant women have elevated serum PSA. PSA levels in serum also vary during menstrual cycles and increase in women with excess androgen. Clinical implications of PSA in amniotic fluid and female serum have been suggested. More studies are needed to further explore their utilities.
Effects of ocular enucleation on the oxidative metabolism of CNS structures and ovarium in female rats. (1980)

In this paper we have studied oxygen uptake of the amygdala, hypothalamus, septal area, anterior cortex (latero-frontal), posterior cortex (latero-occipital) and ovarium in female rats in the oestrous and dioestrous phases with occular enculeation. Our results point to a statistically significant difference in the oestrous phase of the posterior cortex and ovarium levels, comparing control rats with the enucleated ones. In the dioestrous phase, the modifications that we have encountered are at the amygdala and ovarium. We point out the possible participation of the pineal gland in the control of the sexual cycle in in enucleated rats.
Hyperferroelectrics: Proper Ferroelectrics with Persistent Polarization (2014)

All known proper ferroelectrics are unable to polarize normal to a surface or interface if the resulting depolarization field is unscreened, but there is no fundamental principle that enforces this behavior. In this work, we introduce hyperferroelectrics, a new class of proper ferroelectrics which polarize even when the depolarization field is unscreened, this condition being equivalent to instability of a longitudinal optic mode in addition to the transverse-optic-mode instability characteristic of proper ferroelectrics. We use first-principles calculations to show that several recently discovered hexagonal ferroelectric semiconductors have this property, and we examine its consequences both in the bulk and in a superlattice geometry.
A Splice Site Mutant of Maize Activates Cryptic Splice Sites, Elicits Intron Inclusion and Exon Exclusion, and Permits Branch Point Elucidation (1999)

Abstract DNA sequence analysis of thebt2-7503 mutant allele of the maizebrittle-2 gene revealed a point mutation in the 5′ terminal sequence of intron 3 changing GT to AT. This lesion completely abolishes use of this splice site, activates two cryptic splice sites, and alters the splicing pattern from extant splice sites. One activated donor site, located nine nt 5′ to the normal splice donor site, begins with the dinucleotide GC. While non-consensus, this sequence still permits both trans-esterification reactions of pre-mRNA splicing. A second cryptic site located 23 nt 5′ to the normal splice site and beginning with GA, undergoes the first trans-esterification reaction leading to lariat formation, but lacks the ability to participate in the second reaction. Accumulation of this splicing intermediate and use of an innovative reverse transcriptase-polymerase chain reaction technique (J. Vogel, R.H. Wolfgang, T. Borner [1997] Nucleic Acids Res 25: 2030–2031) led to the identification of 3′ intron sequences needed for lariat formation. In most splicing reactions, neither cryptic site is recognized. Most mature transcripts include intron 3, while the second most frequent class lacks exon 3. Traditionally, the former class of transcripts is taken as evidence for the intron definition of splicing, while the latter class has given credence to the exon definition of splicing.
A visual parking guidance for surround view monitoring system (2015)

360 degree surround view system monitoring (SVM) is a very convenient system to help drivers drive through narrow spaces blind-spot-free by looking at surround of a vehicle from top view. Nevertheless, it cannot solve the problem of parking. Even with help of 360 degree SVM system, unexperienced drivers still cannot do parking easily. In this paper, we present a parking guidance for SVM system which guides drivers to do parking step by step easily. One of key technologies of parking guidance or intelligent parking system is the path planning. This paper mainly describes two-arc parking path planning scheme. How the HMI of parking guidance applied on SVM system is also described.
A double‐blind, placebo‐controlled pilot study of ondansetron for patients with obsessive‐compulsive disorder (2010)

The results of this study show that ondansetron has positive effects on obsession and compulsion which start two weeks after the beginning of the treatment.
Clonogenic Assay: Adherent Cells (2011)

The clonogenic (or colony forming) assay has been established for more than 50 years; the original paper describing the technique was published in 1956. Apart from documenting the method, the initial landmark study generated the first radiation-dose response curve for X-ray irradiated mammalian (HeLa) cells in culture. Basically, the clonogenic assay enables an assessment of the differences in reproductive viability (capacity of cells to produce progeny; i.e. a single cell to form a colony of 50 or more cells) between control untreated cells and cells that have undergone various treatments such as exposure to ionising radiation, various chemical compounds (e.g. cytotoxic agents) or in other cases genetic manipulation. The assay has become the most widely accepted technique in radiation biology and has been widely used for evaluating the radiation sensitivity of different cell lines. Further, the clonogenic assay is commonly used for monitoring the efficacy of radiation modifying compounds and for determining the effects of cytotoxic agents and other anti-cancer therapeutics on colony forming ability, in different cell lines. A typical clonogenic survival experiment using adherent cells lines involves three distinct components, 1) treatment of the cell monolayer in tissue culture flasks, 2) preparation of single cell suspensions and plating an appropriate number of cells in petri dishes and 3) fixing and staining colonies following a relevant incubation period, which could range from 1-3 weeks, depending on the cell line. Here we demonstrate the general procedure for performing the clonogenic assay with adherent cell lines with the use of an immortalized human keratinocyte cell line (FEP-1811). Also, our aims are to describe common features of clonogenic assays including calculation of the plating efficiency and survival fractions after exposure of cells to radiation, and to exemplify modification of radiation-response with the use of a natural antioxidant formulation.
Towards quantitative and scalable transformation of furfural to cyclopentanone with supported gold catalysts (2015)

Coupling of small gold nanoparticles with anatase TiO<sub>2</sub> affords by far the most selective and efficient catalytic hydrogenation system to date capable of quantitatively converting bio-derived furfural into renewable cyclopentanone in water.
Parallel<i>in Vivo</i>and<i>in Vitro</i>Detection of Functional Somatostatin Receptors in Human Endocrine Pancreatic Tumors: Consequences with Regard to Diagnosis, Localization, and Therapy (1990)

The effects of octreotide in vivo and in vitro on hormone release, in vivo [123I]Tyr3-octreotide scanning, and in vitro [125I]Tyr3-octreotide autoradiography were compared in five patients with endocrine pancreatic tumors. [123I]Tyr3-octreotide scanning localized the primary tumor and/or previously unknown metastases in four of the five patients. The patient with a negative scan had an insulinoma that did not respond to octreotide in vivo. No Tyr3-octreotide-binding sites were subsequently found at autoradiography of the tumor, whereas somatostatin-14 receptors were present at a high density. In parallel, culture studies with the cells prepared from this adenoma showed that insulin release was not affected by octreotide, while both somatostatin-14 and -28 significantly suppressed hormone release. Culture studies of the tumor cells from two gastrinomas showed a dose-dependent inhibition of gastrin release by octreotide. Octreotide exerted direct antiproliferative effects in one of these gastrinomas, which had been shown to be rapidly growing in vivo. Both gastrinomas had specific somatostatin receptors, as measured by in vitro receptor autoradiography. Somatostatin release by the cultured somatostatinoma cells from one of these patients was suppressed by octreotide. In conclusion, 1) the [123I]Tyr3-octreotide scanning procedure is valuable in the localization of primary endocrine pancreatic tumors as well their often clinically not yet recognized metastases; 2) the in vitro detection of somatostatin receptors in those tumors that were also visualized in vivo after injection of [123I] Tyr3-octreotide indicates that the ligand binding to the tumor in vivo indeed represents binding to specific somatostatin receptors; and 3) the parallel between the presence of somatostatin receptors on tumors and in in vivo and in vitro effects of octreotide on hormonal release from these tumors indicate that a positive scan predicts a good suppressive effect of octreotide on hormonal hypersecretion by these tumors.