gebhart/patrepeval huggingface dataset:
A New Correlation of Propene-Propane Vapor-Liquid Equilibrium Data and Application of the Correlation to Determine Optimum Fractionator Operating Pressure in the Manufacture of Polymerization-Grade Propene (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA New Correlation of Propene-Propane Vapor-Liquid Equilibrium Data and Application of the Correlation to Determine Optimum Fractionator Operating Pressure in the Manufacture of Polymerization-Grade PropeneColin S. Howat III and George W. SwiftCite this: Ind. Eng. Chem. Process Des. Dev. 1980, 19, 2, 318–323Publication Date (Print):April 1, 1980Publication History Published online1 May 2002Published inissue 1 April 1980https://doi.org/10.1021/i260074a021RIGHTS & PERMISSIONSArticle Views214Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (628 KB) Get e-Alerts
One‐Pot Synthesis of Allylic Sulfones, Ketosulfones, and Triflyl Allylic Alcohols from Domino Reactions of Allylic Alcohols with Sulfinic Acid under Metal‐Free Conditions (2015)

Abstract A metal‐free tandem procedure by using a sulfonylation reaction of aryl allylic alcohols followed by an iodobenzenediacetate (PIDA)‐promoted oxidative functionalization has been established. Allylic sulfones, γ‐ketosulfones, and triflyl allylic alcohols have been constructed in a single operation. The methodology incorporates the sulfonyl (both aryl and triflyl) functionality with a simple work‐up procedure.
Weak models for insider threat detection (2004)

This paper describes the design for a content-based approach to detecting insider misuse by an analyst producing reports in an environment supported by a document control system. The approach makes use of Hidden Markov Models to represent stages in the Evidence-Based Intelligence Analysis Process Model (EBIAPM). This approach is seen as a potential application for the Process Query System / Tracking and Fusion Engine (PQS/TRAFEN). Actions taken by the insider are viewed as processes that can be detected in PQS/TRAFEN. Text categorization of the content of analyst's queries, documents accessed, and work product are used to disambiguate multiple EBIAPM processes.
A Meta-Learning Approach to the Optimal Power Flow Problem Under Topology Reconfigurations (2020)

Recently, there has been a surge of interest in adopting deep neural networks (DNNs) for solving the optimal power flow (OPF) problem in power systems. Computing optimal generation dispatch decisions using a trained DNN takes significantly less time when compared to using conventional optimization solvers. However, a major drawback of existing work is that the machine learning models are trained for a specific system topology. Hence, the DNN predictions are only useful as long as the system topology remains unchanged. Changes to the system topology (initiated by the system operator) would require retraining the DNN, which incurs significant training overhead and requires an extensive amount of training data (corresponding to the new system topology). To overcome this drawback, we propose a DNN-based OPF predictor that is trained using a meta-learning (MTL) approach. The key idea behind this approach is to find a common initialization vector that enables fast training for any system topology. The developed OPF-predictor is validated through simulations using benchmark IEEE bus systems. The results show that the MTL approach achieves significant training speeds-ups and requires only a few gradient steps with a few data samples to achieve high OPF prediction accuracy.
Architecture of the Human Ndc80-Hec1 Complex, a Critical Constituent of the Outer Kinetochore (2021)

The Ndc80 complex is a constituent of the outer plate of the kinetochore and plays a critical role in establishing the stable kinetochore-microtubule interactions required for chromosome segregation in mitosis. The Ndc80 complex is evolutionarily conserved and contains the four subunits Spc24, Spc25, Nuf2, and Ndc80 (whose human homologue is called Hec1). All four subunits are predicted to contain globular domains and extensive coiled coil regions. To gain an insight into the organization of the human Ndc80 complex, we reconstituted it using recombinant methods. The hydrodynamic properties of the recombinant Ndc80 complex are identical to those of the endogenous HeLa cell complex and are consistent with a 1:1:1:1 stoichiometry of the four subunits and a very elongated shape. Two tight Hec1-Nuf2 and Spc24-Spc25 subcomplexes, each stabilized by a parallel heterodimeric coiled coil, maintain this organization. These subcomplexes tetramerize via an interaction of the C- and N-terminal portions of the Hec1-Nuf2 and Spc24-Spc25 coiled coils, respectively. The recombinant complex displays normal kinetochore localization upon injection in HeLa cells and is therefore a faithful copy of the endogenous Ndc80 complex.
Bone marrow histologic pattern--the best single prognostic parameter in chronic lymphocytic leukemia: a multivariate survival analysis of 329 cases (1984)

In previous studies, the prognostic value of bone marrow (BM) histologic patterns in chronic lymphocytic leukemia (CLL) has been demonstrated. In order to investigate whether such a value is independent of other prognostic parameters, a multivariate survival analysis (Cox's regression model) was undertaken in a series of 329 CLL patients in whom a BM had been performed. The following binary variables were included in the analysis: age (more than 60 years), lymphadenopathy (more than two areas involved), splenomegaly, hepatomegaly, absolute lymphocyte count (more than 30,000 microL), anemia (hemoglobin less than 10 g/dL), thrombocytopenia (less than 100,000 microL), and BM pattern (diffuse v nondiffuse). Three variables entered the regression at significant level: BM pattern (P less than .001), anemia (P less than .001), and hepatomegaly (P = .03). The model was also tested by expressing the variables in a continuous way when possible. Again, BM pattern entered first in the regression (P less than .001), followed by the hepatomegaly (P = .002), hemoglobin level (P = .02), and lymphadenopathy (P = .04). When both the binary and the continuous models were tested separately in 227 patients with BM as initial staging procedure and in 102 patients in whom this was performed later during the course of the disease, in all instances, BM pattern entered first in the regression at a highly significant level. BM histologic pattern appears to be a better single prognostic parameter than any one of the variables employed in current clinical staging systems. A combined clinicopathologic system incorporating the BM pattern, together with the usual clinical variables, is presented.
Flexible transbronchial optical frequency domain imaging smart needle for biopsy guidance (2012)

Transbronchial needle aspiration (TBNA) is a procedure routinely performed to diagnose peripheral pulmonary lesions. However, TBNA is associated with a low diagnostic yield due to inappropriate needle placement. We have developed a flexible transbronchial optical frequency domain imaging (TB-OFDI) catheter that functions as a "smart needle" to confirm the needle placement within the target lesion prior to biopsy. The TB-OFDI smart needle consists of a flexible and removable OFDI catheter (430 µm dia.) that operates within a standard 21-gauge TBNA needle. The OFDI imaging core is based on an angle polished ball lens design with a working distance of 160 µm from the catheter sheath and a spot size of 25 µm. To demonstrate the potential of the TB-OFDI smart needle for transbronchial imaging, an inflated excised swine lung was imaged through a standard bronchoscope. Cross-sectional and longitudinal OFDI results reveal the detailed network of alveoli in the lung parenchyma suggesting that the TB-OFDI smart needle may be a useful tool for guiding biopsy acquisition to increase the diagnostic yield.
Regulation of toxin synthesis in <i>Clostridium difficile</i> by an alternative RNA polymerase sigma factor (2001)

Clostridium difficile, a causative agent of antibiotic-associated diarrhea and its potentially lethal form, pseudomembranous colitis, produces two large protein toxins that are responsible for the cellular damage associated with the disease. The level of toxin production appears to be critical for determining the severity of the disease, but the mechanism by which toxin synthesis is regulated is unknown. The product of a gene, txeR, that lies just upstream of the tox gene cluster was shown to be needed for tox gene expression in vivo and to activate promoter-specific transcription of the tox genes in vitro in conjunction with RNA polymerases from C. difficile, Bacillus subtilis, or Escherichia coli. TxeR was shown to function as an alternative sigma factor for RNA polymerase. Because homologs of TxeR regulate synthesis of toxins and a bacteriocin in other Clostridium species, TxeR appears to be a prototype for a novel mode of regulation of toxin genes.
Josephson Parametric Reflection Amplifier with Integrated Directionality (2018)

Detecting faint light from deep space requires an excellent signal-to-noise ratio, as does quantum information processing. For microwave and terahertz frequencies, a simple directional amplifier offering minimal added loss and easy on-chip integration would be a major step forward. This study envisions such an amplifier as two Josephson-junction oscillators plus an on-chip passive circuit, promising 20 dB of gain while adding only ~1 photon s${}^{\ensuremath{-}1}$ Hz${}^{\ensuremath{-}1}$ of noise. This work addresses scale-up in circuit QED and detector research by integrating directional signal routing and amplification, allowing more qubits or pixels per unit area.
Compiling parallel applications to Coarse-Grained Reconfigurable Architectures (2008)

In this paper a novel approach for compiling parallel applications to a target coarse-grained reconfigurable architecture (CGRA) is presented. We have given a formal definition of the compilation problem for the CGRA. The application will be written in HARPO/L, a parallel object oriented language suitable for hardware. HARPO/L is first compiled to a data flow graph (DFG) representation. The remaining compilation steps are a combination of three tasks: scheduling, placement and routing. For compiling cyclic portions of the application, we have adapted a modulo scheduling algorithm: modulo scheduling with integrated register spilling. For scheduling, the nodes of the DFG are ordered using the hypernode reduction modulo scheduling (HRMS) method. The placement and routing is done using the neighborhood relations of the PEs.
PES of higher temperature vapors: Lithium halide monomers and dimers (1979)

The He (I) photoelectron spectra of ’’pure’’ monomers and dimers of the lithium halides have been obtained by using a double-oven technique to vary the dimer:monomer ratio. The lithium halide monomer spectra conform nicely to a model based on spin–orbit and ligand field interactions previously introduced. The first ionization potentials of the dimers are in each case higher than in the corresponding monomers. These conclusions are also deduced in this paper by ionic model calculations and molecular calculations of the X-α type, using the discrete variational method. The X-α calculations enable us to assign tentatively the dimer valence bands. These calculations have been extended to trimer and tetramer structures and indicate an oscillation in the first ionization potential in the series encompassing monomer through tetramer. Some experimental verification exists up to trimer. The oscillatory behavior is also obtained in a crude ionic model calculation. An experimental method using photoionization mass spectrometry is suggested for the study of larger clusters and is tested for Na2I2.
Methionine Sulfoxide and Proteolytic Cleavage Contribute to the Inactivation of Cathepsin G by Hypochlorous Acid (2005)

Using myeloperoxidase and hydrogen peroxide, activated neutrophils produce high local concentrations of hypochlorous acid (HOCl). They also secrete cathepsin G, a serine protease implicated in cytokine release, receptor activation, and degradation of tissue proteins. Isolated cathepsin G was inactivated by HOCl but not by hydrogen peroxide in vitro. We found that activated neutrophils lost cathepsin G activity by a pathway requiring myeloperoxidase, suggesting that oxidants generated by myeloperoxidase might regulate cathepsin G activity in vivo. Tandem mass spectrometric analysis of oxidized cathepsin G revealed that loss of a peptide containing Asp108, which lies in the active site, associated quantitatively with loss of enzymatic activity. Catalytic domain peptides containing Asp108 were lost from the oxidized protein in concert with the conversion of Met110 to the sulfoxide. Release of this peptide was blocked by pretreating cathepsin G with phenylmethylsulfonyl fluoride, strongly implying that oxidation introduced proteolytic cleavage sites into cathepsin G. Model system studies demonstrated that methionine oxidation can direct the regiospecific proteolysis of peptides by cathepsin G. Thus, oxidation of Met110 may contribute to cathepsin G inactivation by at least two distinct mechanisms. One involves direct oxidation of the thioether residue adjacent to the aspartic acid in the catalytic domain. The other involves the generation of new sites that are susceptible to proteolysis by cathepsin G. These observations raise the possibility that oxidants derived from neutrophils restrain pericellular proteolysis by inactivating cathepsin G. They also suggest that methionine oxidation could render cathepsin G susceptible to autolytic cleavage. Myeloperoxidase may thus play a previously unsuspected role in regulating tissue injury by serine proteases during inflammation.
SYNTHESIS OF NANOCRYSTALLINE YIG USING MICROWAVE-HYDROTHERMAL METHOD (2009)

The aim of present research is to study the influence of sintering temperature on the preparation of nanocrystalline Yttrium Iron garnet (YIG) with improved magnetic properties. The nanocrystalline YIG powders were synthesized using Microwave-Hydrothermal (M-H) method. The synthesized powders were characterized using X-ray diffraction (XRD) and Transmission Electron Microscope (TEM). The powders were sintered at various temperatures using microwave sintering method. The sintered samples were characterized using XRD. The complex permeability, dielectric constant and loss tangent of sintered YIG ceramic were also measured and discussed in this paper
The <i><scp>B</scp>rassica napus</i> blackleg resistance gene <scp><i>LepR3</i></scp> encodes a receptor‐like protein triggered by the <i><scp>L</scp>eptosphaeria maculans</i> effector <scp>AVRLM</scp>1 (2012)

LepR3, found in the Brassica napus cv 'Surpass 400', provides race-specific resistance to the fungal pathogen Leptosphaeria maculans, which was overcome after great devastation in Australia in 2004. We investigated the LepR3 locus to identify the genetic basis of this resistance interaction. We employed a map-based cloning strategy, exploiting collinearity with the Arabidopsis thaliana and Brassica rapa genomes to enrich the map and locate a candidate gene. We also investigated the interaction of LepR3 with the L. maculans avirulence gene AvrLm1 using transgenics. LepR3 was found to encode a receptor-like protein (RLP). We also demonstrated that avirulence towards LepR3 is conferred by AvrLm1, which is responsible for both the Rlm1 and LepR3-dependent resistance responses in B. napus. LepR3 is the first functional B. napus disease resistance gene to be cloned. AvrLm1's interaction with two independent resistance loci, Rlm1 and LepR3, highlights the need to consider redundant phenotypes in 'gene-for-gene' interactions and offers an explanation as to why LepR3 was overcome so rapidly in parts of Australia.
Iterative joint channel estimation and detection combined with pilot-tone symbols in convolutionally coded ofdm systems (2004)

This paper presents a maximum a posteriori (MAP) joint channel estimator and detector for convolutionally coded OFDM systems over mobile radio communication channels, which is suitable for turbo principles. To the purpose of the synchronization, the several papers where a known pilot-tone symbol [T.P. Holden and K. Feher, 1990], [P. Hoeher and F. Tufvesson, 1999] is transmitted simultaneously, were proposed. This pilot-tone symbol technique is applied to the channel estimation for OFDM systems, so that it gives the use of decision-directed algorithm based on the symbol-by-symbol MAP algorithm, which is optimal detection algorithm [L.R. Bahl et al., 1974] in terms of bit error rate (BER). However, in the presence of unknown quantities, since the symbol MAP algorithm is not optimal, the MAP algorithm, which is jointly linked with per-survivor processing (PSP) algorithm [R. Raheli, et al., 1995], is required. Instead of one 2-dimensional channel estimation scheme [P. Hoeher et al., 1997], two 1-dimensional channel estimation techniques with convolutional codes are presented in an iterative receiver structure. Hence, the proposed iterative joint estimation and detection algorithm gives the reliability values to the component decoder for convolutional codes, which is combined with pilot-tone technique, to obtain the better performance in the iterative way. Simulations demonstrate the performance of the proposed iterative joint channel estimator and detector.
C-myc protooncogene modulates cardiac hypertrophic growth in transgenic mice (1992)

Protooncogenes such as c-myc have been implicated in the transduction of growth signals in the cardiac myocyte. We examined whether increases in c-myc expression occur in murine heart in vivo as a generalized response to the pharmacological stimulation of myocyte growth. Both triiodothyronine (T3) and the beta-adrenergic agonist isoproterenol were demonstrated to induce a rapid and transient increase in cardiac c-myc mRNA abundance, which preceded an increase in cardiac mass. We then examined whether myocyte growth could be modulated by selectively altering cardiac c-myc expression. The model system used was a strain of transgenic mice exhibiting a 20-fold increase in cardiac c-myc expression. Although in nontransgenic mice the administration of T3 and isoproterenol resulted in similar increases in cardiac mass, in transgenic mice the degree of myocardial growth induced with T3 was significantly greater than that induced with isoproterenol (P less than 0.001). This study demonstrates that increasing the basal expression of c-myc in cardiac myocytes alters the growth response of the heart in vivo to certain hypertrophic stimuli and implicates the c-myc protooncogene in the transduction of selective hypertrophic growth signals in differentiated cardiac myocytes.
Expression of G protein alpha-subunits in bovine parathyroid (1995)

A G protein-coupled Ca(2+)-sensing receptor was recently cloned from bovine parathyroid and shown to mediate divalent cation regulation of PTH secretion. To define which G proteins might be coupled to the Ca(2+)-sensing receptor in parathyroid cells, we determined which G protein alpha-subunit messenger RNAs (mRNAs) are expressed in the parathyroid. We also considered the possibility that a novel parathyroid-specific G alpha might be present. We, therefore, used the reverse transcription-polymerase chain reaction to study the expression of G alpha subunits in a bovine parathyroid mRNA preparation. Degenerate primers, corresponding to two regions conserved in every G alpha subunit, the G3 and G4 sequences, were used to amplify G alpha complementary DNA fragments that were subcloned and sequenced. We found that mRNAs corresponding to G alpha s, G alpha i2, G alpha 11, G alpha 12, and G alpha z are the predominant G alpha mRNAs expressed in the bovine parathyroid. No novel G alpha mRNA was identified. Northern blots confirmed the expression of the cloned G alpha subunits and showed lower expression of G alpha o and G alpha i1 mRNAs. Immunoblots confirmed abundant expression of G alpha s, G alpha i2, and G alpha 11 and provided evidence for expression of G alpha i1 and G alpha i3, but not G alpha o. G alpha q mRNA was not identified by the degenerate primer reverse transcription-polymerase chain reaction strategy, but the immunoblot detected G alpha q protein, albeit at considerably lower levels than G alpha 11. The abundance of G alpha 11 relative to G alpha q in bovine parathyroid is consistent with but does not prove a role for G alpha 11 in coupling the Ca(2+)-sensing receptor to phospholipase C.
Viscosification of Oilfield Brines: Guidelines for the Prevention of Unexpected Formation Damage (2000)

Abstract Polymer viscosified oilfield brines have been accepted by the industry and routinely used to transport sand in gravel pack applications, to control fluid loss to the formation, and in other oilfield applications. However, recent observations of precipitate formation from heat aged viscosified brines indicated that the thermal stability of viscosified oilfield brines can vary dramatically. Variations were observed not only for the same polymer in different oilfield brines, but also for the same polymer from a different source in the same brine, and even for the same polymer in different concentrations of the same brine. This paper details the systematic study conducted to identify and map the safe operating environments for selected oilfield polymers used to viscosify standard oilfield brines. Polymer viscosified brines were prepared by standard procedures, and statically heat aged at prescribed temperatures. The clarity of aged samples, including precipitation and separation tendencies, retained viscosities, and return permeability measurements were used to determine thermal stability. Systematic polymer-brine composition-temperature relationships were observed, and certain combinations were found to be a significant source of unexpected polymer precipitation and formation damage. Results from this study provide the basic guidelines for the selection and field application of polymer viscosifiers for oilfield brines presented in this paper. Details concerning the viscosification process, its impact on TCT (True Crystallization Temperature), and the viscosification of zinc based brines are outlined. A two step viscosification process for brines containing low zinc concentrations is presented.
Evaluation of performance of Beijing expressway based on integrated GPS/GIS data (2006)

For years, Beijing government has put large sums of capital into transport infrastructure constructions, building expressways and implementing advanced transport management systems to alleviate urban traffic congestions. However, what bothers the government decision makers is that they often have deficient information on whether the new expressway and applications of the system they proved do perform the expected function in urban traffic system. For this, a method for expressway function evaluation based on integrated GPS/GIS data (EFIG) was developed which proved to be a useful tool for government decision and policy makers. A case in Beijing will be presented to illustrate the details