gebhart/patrepeval huggingface dataset:
Regiochemical control of the addition of aryl selenols and aryl thiols to the triple bond of arylpropiolates. Synthesis of seleno- and thioflavones and seleno- and thioaurones (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRegiochemical control of the addition of aryl selenols and aryl thiols to the triple bond of arylpropiolates. Synthesis of seleno- and thioflavones and seleno- and thioauronesDonald H. Wadsworth and Michael R. DettyCite this: J. Org. Chem. 1980, 45, 23, 4611–4615Publication Date (Print):November 1, 1980Publication History Published online1 May 2002Published inissue 1 November 1980https://pubs.acs.org/doi/10.1021/jo01311a013https://doi.org/10.1021/jo01311a013research-articleACS PublicationsRequest reuse permissionsArticle Views641Altmetric-Citations84LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Design and measurement of an integrated wideband radio frequency low-noise amplifier for terrestrial digital television applications (2010)

Abstract In this article, the design and measurement details of a wideband low-noise amplifier (LNA) are presented. The LNA was successfully designed to operate over very high and ultra high frequency (VHF and UHF) ranges according to Digital TV (DVB-T) specifications. The novelty of the design lies in the achievement of low noise figure (NF) and high reverse isolation level across a wide bandwidth despite the resistive feedback topology. The latter was required in order to integrate the front-end block with a direct-conversion receiver. A measured large-signal compression point of P1dB = −10 dBm and a small-signal gain of 16 dB with gain flatness of <1 dB ripple, have all met commercial specifications tested over corners. The NF achieved was better than that specified and was less than 2 dB across the bandwidth. This front-end block was implemented in a commercial 0.25 μm Si BiCMOS process (f T = 20 GHz). The article discusses the measurement uncertainties imposed by the wide bandwidth, particularly in NF measurements, and the techniques adopted in this work to mitigate the errors imposed. Keywords: low-noise amplifierwidebanddirect-conversionDVB-TBiCMOSmeasurement
Diffusivities of Uranium in Artificial Seawater (1981)

人工海水中におけるウランの拡散係数を, ウラン濃度10～1,000μg-U/l, 液温5～35℃の範囲で測定した.その結果, 拡散係数は次の実験式で示された.D=0.0475exp (-23,500/RT) ここで, Dは拡散係数 [cm2/s], Rはガス定数 [J/mol・K], Tは温度 [K] である.
Lipid peroxidation as a mechanism of acute nickel toxicity<sup>†</sup> (1987)

Studies in the author's laboratory have shown that (a) concentrations of thiobarbituric acid (TBA) chromogens are increased in target tissues (liver, kidney, lung) of NiCl2‐treated rats; (b) severity of hepatic toxicity, assessed by serum aspartate aminotransferase activity, is generally proportional to the elevation of hepatic TBA‐chromogens, based upon the time‐courses and dose‐effect relationships observed after administration of NiCl2 to rats; (c) concentrations of conjugated dienes are greatly elevated in lipid extracts of hepatic microsomes from NiCl2‐treated rats; (d) NiCl2‐toxicity in rats is attended by increased exhalation of ethane and ethylene, decreased erythrocyte deformability, and elevated concentrations of plasma lipoperoxides. Studies in other laboratories have shown that (e) TBA‐chromogens are increased in brain homogenates of rats after repeated daily injections of NiCl2; (f) hepatic microsomes from NiCl2‐treated rats yield increased rates of lipid peroxidation when incubated in vitro with NADPH or ascorbate; and (g) addition of NiCl2 to rat liver homogenates stimulates lipid peroxidation during in vitro incubation with NADPH or ascorbate. These experimental findings support the conclusion that lipid peroxidation constitutes a molecular mechanism of acute nickel toxicity.
Multi-bits coding by multi-directional valley pits permitting stamper mass-production and remote direction readout by polarization reflection (2008)

A new concept of high-density memories by arrays of multidirectional V-shape pits and remote polarization readout is proposed. The polarization readout principles are examined by two model experiments. The first experiment with an array of 1 mum deep V-pits fabricated by FIB on a Si wafer, carried out under polarization microscope observation, confirmed the concept by the expected contrast variation among the pits images. Accuracy of the remote readout was examined by the second experiment configuring total reflection V-pits by a rectangular prism glued underneath a glass plate. Polarization detection sensitivity of the V-pit direction was found to be +/-0.14 degrees , which should easily accommodate 1.4 degrees =180 degrees /128 separation for 7 bits recording at every single V-pit.
Specification and verification of event detectors and responses (2013)

Events and aspects that respond to them can and should be defined, specified, and verified in a modular way, as an aid in understanding and guaranteeing the correctness of each on its own. However, finding the appropriate interfaces and abstractions and expressing them precisely is not an easy task. Moreover, formally verifying large models is often unfeasible for existing model-checking tools.
Famotidine as an adjunct treatment of resistant schizophrenia. (1994)

Some patients suffering from schizophrenia fail to respond to or tolerate adequate doses of available antipsychotic medications. Thus, innovative pharmacotherapeutic approaches, such as augmentation strategies, play an important role in the management of these treatment-resistant patients. A recent case report suggested that the administration of famotidine to a patient suffering from schizophrenia with peptic ulcer disease was associated with improvement in the deficit symptoms of schizophrenia. Famotidine is a potent highly selective H2 receptor antagonist which crosses the blood-brain barrier. Impressed by this finding, famotidine was prescribed to some of our treatment-resistant patients suffering from schizophrenia who demonstrated significant deficit symptoms of schizophrenia. The subjects were 12 (eight male, four female) treatment-resistant psychotic patients whose antipsychotic medications were augmented with famotidine in an open trial. They ranged in age from 21 to 48 years with a mean age of 32.75 years. Seven of the 12 subjects made significant improvement resulting in discharge from hospital. Paranoid disturbances as well as absence of comorbid substance use were predictors of good response to famotidine augmentation of the antipsychotic medications. The results implied that H2 receptor activity in the brain might play a role in the pathogenesis of deficit syndromes in schizophrenia. Further studies of this strategy are recommended, since it may open a window of understanding of the negative (deficit) syndrome and its treatment.
Trafficking of gap junction channels at a vertebrate electrical synapse in vivo (2012)

Trafficking and turnover of transmitter receptors required to maintain and modify the strength of chemical synapses have been characterized extensively. In contrast, little is known regarding trafficking of gap junction components at electrical synapses. By combining ultrastructural and in vivo physiological analysis at identified mixed (electrical and chemical) synapses on the goldfish Mauthner cell, we show here that gap junction hemichannels are added at the edges of GJ plaques where they dock with hemichannels in the apposed membrane to form cell-cell channels and, simultaneously, that intact junctional regions are removed from centers of these plaques into either presynaptic axon or postsynaptic dendrite. Moreover, electrical coupling is readily modified by intradendritic application of peptides that interfere with endocytosis or exocytosis, suggesting that the strength of electrical synapses at these terminals is sustained, at least in part, by fast (in minutes) turnover of gap junction channels. A peptide corresponding to a region of the carboxy terminus that is conserved in Cx36 and its two teleost homologs appears to interfere with formation of new gap junction channels, presumably by reducing insertion of hemichannels on the dendritic side. Thus, our data indicate that electrical synapses are dynamic structures and that their channels are turned over actively, suggesting that regulated trafficking of connexons may contribute to the modification of gap junctional conductance.
Using Extended EM to Segment Planar Structures in 3D (2006)

The proposed algorithm segments planar structures out of data gained from 3D laser range scanners, typically used in robotics. The approach first fits planar patches to the dataset, using a new, extended expectation maximization (EM) algorithm. This algorithm solves the classical EM problems of insufficient initialization by iteratively determining the number and positions of patches in a split and merge framework. Determining the fitting quality of the gained patches, the approach then allows for segmentation of planar surfaces out of the 3D environment. The result is a set of 2D objects, which can be used as input for classical computer vision applications, in particular for object recognition. Our approach makes it possible to apply classical tools of 2D image processing to solve problems of 3D robot mapping, e.g. landmark recognition
Radiosensitization of Pancreatic Cancer Cells In Vitro and In Vivo through Poly (ADP-ribose) Polymerase Inhibition with ABT-888 (2014)

ABT-888 with radiation significantly enhanced tumor response in vitro and in vivo. ABT-888 inhibited PAR protein polymerization resulting in dose-dependent feedback up-regulation of PARP and p-ATM suggesting increased DNA damage. This translated into enhancement in TGI and survival with radiation in vivo. In vitro PAR levels correlated with levels of tumor apoptosis suggesting potential as a predictive biomarker. These data are being used to support a Phase I study in locally advanced pancreatic cancer.
Perspective Correct Hand-held Augmented Reality for Improved Graphics and Interaction (2018)

I would like to thank all the people that helped me during my research, making my Ph.D. studies enjoyable and memorable.
Surface Soil Moisture Simulation for a Typical Torrential Event with a Modified Noah LSM Coupling to the NWP Model (2011)

表面土壤潮湿在两个中央上有大影响 -- 并且 microscale 大气的过程，特别在严重本地传送对流过程上并且在短命的奔流的雨的动力学上。为了在表面支持陆地表面模型( LSM )的表演，玷污潮湿模拟，在 Xin'anjiang 模型和地形学的必要建模理论之上基于的一个混合 hydrologic 流量 parameterization 计划基于水文学模型( TOPMODEL )在诺亚·尔斯姆在偏爱被开发到简单的水平衡模型( SWB )。用为联合并且集成的策略，这修改了诺亚·尔斯姆到全球 / 地区性的吸收和预言系统(葡萄) 类似于与标准诺亚·尔斯姆，一起使用了那为一个奔流的事件的空气陆地表面相互作用的模拟在山东在 2007 期间被尝试。结果建议表面，葡萄用修改 hydrologic 途径模仿的 10 厘米的深度土壤潮湿与观察同意很好。从模仿的结果的改进被发现，特别在东方山东上。与扫描观察系统(AMSR-E ) 土壤潮湿数据集的辐射计地球的先进微波的产品相比，模仿的结果中国在所有上显示了一个一致空间模式。表面土壤潮湿的时间的变化在一个观察车站与数据被验证，也证明有修改诺亚·尔斯姆展览的葡萄对降水事件的更合理的回答，尽管偏爱和系统的趋势可以仍然存在。
Serum and tissue trace elements in colorectal cancer (1993)

Serum copper, zinc, and Cu/Zn ratio were measured using atomic absorption spectrophotometry in 30 patients with colorectal cancer and compared with 30 healthy control subjects. In the patients with colorectal cancer, the tissue copper and zinc levels were also measured in paired histologically normal and malignant colorectal tissue samples obtained at surgery. The mean serum copper levels were higher in patients with colorectal cancer (165.99 vs. 98.84 micrograms/dl) (P < 0.001). The mean serum zinc levels were lowered only in advanced (Dukes stages C and D) colorectal cancer compared to controls (89.94 vs. 115.08 mu/dl) (P < 0.001). However, the Cu/Zn ratio progressively increased with the advancing stage of malignancy (1.86 vs. 0.86) (P < 0.001). The cancerous colorectal tissue showed a higher concentration of both copper (2.78 vs. 1.79 micrograms/g) (P < 0.001) and zinc (27.16 vs. 18.98 micrograms/g) (P < 0.01) compared to non-cancerous colorectal tissue. The exact mechanism responsible for the alterations in trace element levels in patients with colorectal cancer is largely unclear and requires further evaluation. However, the serum copper level and the Cu/Zn ratio are of value in estimating the extent of the carcinoma as well as in determining the prognosis of these patients.
Carbon Nanotubes with Covalently Linked Porphyrin Antennae:  Photoinduced Electron Transfer (2005)

Single- and multiwalled carbon nanotubes have been covalently functionalized with free-base porphyrin. The quantity of porphyrin linked to the surface was determined from thermogravimetric and UV-vis analysis. A reversible protonation equilibrium between the attached porphyrin and the residual acid groups of the carbon nanotubes has been identified. Steady-state fluorescence emission spectrum of the solutions of porphyrin-linked carbon nanotubes shows that the porphyrins act as energy absorbing and electron transferring antennae, and the carbon nanotubes act as efficient electron acceptors. The porphyrin-linked carbon nanotubes show 95-100% emission quenching, indicating a fast photoinduced electron transfer.
Structural Color Patterns by Electrohydrodynamic Jet Printed Photonic Crystals (2017)

In this work, we demonstrate the fabrication of photonic crystal patterns with controllable morphologies and structural colors utilizing electrohydrodynamic jet (E-jet) printing with colloidal crystal inks. The final shape of photonic crystal units is controlled by the applied voltage signal and wettability of the substrate. Optical properties of the structural color patterns are tuned by the self-assembly of the silica nanoparticle building blocks. Using this direct printing technique, it is feasible to print customized functional patterns composed of photonic crystal dots or photonic crystal lines according to relevant printing mode and predesigned tracks. This is the first report for E-jet printing with colloidal crystal inks. Our results exhibit promising applications in displays, biosensors, and other functional devices.
Effect of Hot Air Oven and Microwave Oven Drying on Production of Quality Dry Flowers of Dutch Roses (2013)

The present investigation was conducted to evaluate different oven drying methods for obtaining better quality dried flowers of four Dutch rose cultivars viz., Skyline, Lambada, Ravel’ and First Red. Flowers dried at 40°C in hot air oven with silica gel were more acceptable for colour (3.48), appearance (3.50) and texture (3.23). Flowers dried by non-embedding method took least time (52.32 hours) for drying compared to embedded method. Flowers of ‘Lambada’ dried without embedding took least time for drying (52.07 hours) in hot air oven compared to other cultivars. Quality parameters such as colour (3.48), appearance (3.51) and texture (3.29) were superior in flowers dried for 2.5 minutes in microwave oven by embedding in silica gel. Flowers of ‘Lambada’ dried for 2.5 minutes by embedding in silica gel were best for overall acceptability, while unacceptable quality was obtained in case of flowers dried without any embedding medium. With respect to mode of desiccation, embedded drying was best for quality parameters viz., colour (2.92), appearance (2.81) and texture (2.55); however, non-embedding methods were least acceptable for quality parameters. Flowers of cv. ‘Lambada’ dried by embedding in silica gel yielded best quality dried flowers as it scored maximum point for all the quality parameters studied.
INFECT: INconspicuous FEC-based Trojan: A hardware attack on an 802.11a/g wireless network (2017)

We discuss the threat that hardware Trojans (HTs) impose on wireless networks, along with possible remedies for mitigating the risk. We first present an HT attack on an 802.11a/g transmitter (TX), which exploits Forward Error Correction (FEC) encoding. While FEC seeks to protect the transmitted signal against channel noise, it often offers more protection than needed by the actual channel. This margin is precisely where our HT finds room to stage an attack. We, then, introduce a Trojan-agnostic method which can be applied at the receiver (RX) to detect such attacks. This method monitors the noise distribution, to identify systematic inconsistencies which may be caused by an HT. Lastly, we describe a Wireless open-Access Research Platform (WARP) based experimental setup to investigate the feasibility and effectiveness of the proposed attack and defense. More specifically, we evaluate (i) the ability of a rogue RX to extract the leaked information, while an unsuspecting, legitimate RX accurately recovers the original message and remains oblivious to the attack, and (ii) the ability of channel noise profiling to detect the presence of the HT.
ArchFP: Rapid prototyping of pre-RTL floorplans (2012)

There has been a fundamental shift from ever more complex single cores to single chip multi-core (CMP) designs. Along with this opportunity come major challenges; notably the sheer size of the CMP design space. An integrated suite of tools is needed that provides life-cycle support from early prototyping to final design. Here we present ArchFP, a floorplanning tool targeted towards prototyping of pre-RTL CMP design concepts. As such, it is complementary to traditional floorplanners that are more appropriate later in the design cycle.
CB<sub>2</sub>receptors in the brain: role in central immune function (2007)

Recently, it has been recognized that the cannabinoid receptor CB2 may play a functionally relevant role in the central nervous system (CNS). This role is mediated primarily through microglia, a resident population of cells in the CNS that is morphologically, phenotypically, and functionally related to macrophages. These cells also express the cannabinoid receptor CB1. The CB1 receptor (CB1R) is constitutively expressed at low levels while the CB2 receptor (CB2R) is expressed at higher levels and is modulated in relation to cell activation state. The relatively high levels of the CB2R correspond with microglia being in 'responsive' and 'primed' states, suggesting the existence of a 'window' of functional relevance during which activation of the CB2R modulates microglial activities. Signature activities of 'responsive' and 'primed' microglia are chemotaxis and antigen processing, respectively. The endocannabinoid 2-arachidonylglycerol has been reported to stimulate a chemotactic response from these cells through the CB2R. In contrast, we have shown in vivo and in vitro that the exogenous cannabinoids delta-9-tetrahydrocannabinol and CP55940 inhibit the chemotactic response of microglia to Acanthamoeba culbertsoni, an opportunistic pathogen that is the causative agent of Granulomatous Amoebic Encephalitis, through activation of the CB2R. It is postulated that these exogenous cannabinoids superimpose an inhibitory effect on pro-chemotactic endocannabinoids that are elicited in response to Acanthamoeba. Furthermore, the collective results suggest that the CB2R plays a critical immune functional role in the CNS.
Identification of a genetic determinant responsible for host specificity in <i>Streptococcus thermophilus</i> bacteriophages (2001)

Phage-host interactions remain poorly understood in lactic acid bacteria and essentially in all Gram-positive bacteria. The aim of this study was to identify the phage genetic determinant (anti-receptor) involved in the recognition of Streptococcus thermophilus hosts. The complete genomic sequence of the lytic S. thermophilus phage DT1 was determined previously, and bioinformatic analysis indicated that orf18 might be the anti-receptor gene. The orf18 of six additional S. thermophilus phages was determined (DT2, DT4, MD1, MD2, MD4 and Q5) and compared with the orf18 of DT1. The deduced ORF18 was divided into three domains. The first domain, which contains the N-terminal part of the protein, was conserved in all seven phages. The second domain was detected in only two phages and flanked by a motif called collagen-like repeats. The second domain also contained a variable region (VR1). All seven phages had a third domain that consisted of the C-terminal section of the protein as well as another variable region (VR2). Chimeric DT1 phages were constructed by recombination; a portion of its orf18 was replaced by the corresponding section in orf18 of the phage MD4. All DT1 chimeric phages acquired the host range of phage MD4. Analysis of the orf18 in the chimeric phages revealed that host specificity in phages DT1 and MD4 resulted from VR2. This is the first report on the identification and characterization of a phage gene involved in the host recognition process of Gram-positive bacteria.
An investigative analysis of the security weaknesses in the evolution of RFID enabled passport (2012)

Since the introduction of radio frequency identification (RFID) enabled passports, the system has been plagued with various vulnerability issues that prove to compromise the e-passport security. To date, three generations of e-passports have been introduced by the International Civil Aviation Organization (ICAO) and the European Union (EU). The first two generations of e-passports are being issued worldwide. This paper presents the evolution of these passports over the years to develop taxonomy of the weaknesses and to serve as a reference point detailing security vulnerabilities linked to the RFID e-passport features in the three generations. The findings can also assist in profiling possible attack vectors on the existing RFID enabled passports and in developing comprehensive RFID e-passport risk mitigation strategies. To illustrate the importance of a comprehensive risk strategy when using RFID e-passport, the attack process modelling method is used to highlight the possible attacks and weaknesses which could result from not using one or more security features.
Recent developments in bootstrapping time series (2000)

Bootstrap, ARLIA, Frequency Domain, Blocks,
Reshaping the eyebrow by follicular unit transplantation from excised eyebrow in extended infrabrow excision blepharoplasty (2012)

Our study demonstrated excellent results with hair transplantation from eyebrow to eyebrow, a finding which, to our knowledge, has not been previously reported. Our method can be used for selected patients, especially men, with moderate to severe dermatochalasis, who find a reduction or change in the shape of the eyebrow unacceptable.