gebhart/patrepeval huggingface dataset:
Microplate-Based Colorimetric Detection of Free Hydrogen Sulfide (2013)

Hydrogen sulfide (H2S) has recently been recognized as an important physiologically relevant gasotransmitter. Produced by the enzymes involved in the transsulfuration pathway, cystathionine β-synthase (CBS) and cystathionine γ-lyase (CSE), H2S has been implicated to control biological activity in virtually every organ system. In recent years it is being recognized that many commonly used H2S assays do not measure free H2S specifically and may be prone to artifacts. This has led to large variations in the reported H2S biological concentrations. In order to accurately study H2S's functions in biological systems accurate assays which measure free H2S specifically are required. In this work we present a simple microplate-based colorimetric assay for H2S gas. The underside of a 96-well microplate cover was coated with Nafion polymer doped with Ag(+) ions. H2S is a highly volatile gas, and as it is volatilized in the microplate well it reacts with Ag(+) to produce Ag2S nanoparticles, which have a strong absorbance in the low-UV range. By monitoring the absorbance change from formation of Ag2S nanoparticles, H2S production can be monitored in real time. The assay has a limit of detection (LOD) of 2.61 nmol (8.70 μM) and a liner range up to 30 nmol (100 μM). Using the assay, the KM and Vmax of recombinant CSE enzyme were determined to be 11.13 ± 0.57 mM and 0.45 ± 0.01 nmol min(-1), respectively. H2S production from mouse liver homogenate under aerobic conditions in the presence of cysteine was measured and determined to be 4.89 ± 0.19 nmol min(-1) mL(-1) homogenate. The assay is simple, low cost, and specific to free H2S gas.
La correspondencia privada entre letrados como medio de prueba: un tema muy polémico (1) (2016)

Este articulo plantea la problematica relativa a la aportacion procesal de correspondencia privada entre letrados, poniendo de manifiesto la mayoritaria doctrina judicial que se muestra favorable a su admisibilidad como prueba, si bien el autor del estudio destaca la reprochable actuacion del abogado que aporta dicha correspondencia vulnerando la prohibicion contenida en las diversas normativas deontologicas reguladoras de la Abogacia.
A Mode-Matched Silicon-Yaw Tuning-Fork Gyroscope With Subdegree-Per-Hour Allan Deviation Bias Instability (2008)

In this paper, we report on the design, fabrication, and characterization of an in-plane mode-matched tuning-fork gyroscope (M <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> -TFG). The M <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> -TFG uses two high-quality-factor (Q) resonant flexural modes of a single crystalline silicon mi- crostructure to detect angular rate about the normal axis. Operating the device under mode-matched condition, i.e., zero-hertz frequency split between drive and sense modes, enables a Q -factor mechanical amplification in the rate sensitivity and also improves the overall noise floor and bias stability of the device. The M <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> -TFG is fabricated on a silicon-on-insulator substrate using a combination of device and handle-layer silicon etching that precludes the need for any release openings on the proof-mass, thereby maximizing the mass per unit area. Experimental data indicate subdegree-per-hour Brownian noise floor with a measured Allan deviation bias instability of 0.15deg /hr for a 60-mum-thick 1.5 mm X 1.7 mm footprint M <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> -TFG prototype. The gyroscope exhibits an open-loop rate sensitivity of approximately 83 mV/deg/s in vacuum. [2007-0100].
Critical Quenching Speed Determining Phase of Ge<sub>2</sub>Sb<sub>2</sub>Te<sub>5</sub> in Phase--Change Memory (2006)

During the phase-change process of Ge <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> Sb <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> Te <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">5</sub> in PRAM (Phase--hange Random Access Memory), phase-change dynamics are strongly dependent on the quenching speed, i.e. the cooling speed of melted phase--change material. Here we report the relation between quenching speed of programming pulse and phases of Ge <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> Sb <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> Te <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">5</sub> in phase--change memory in detail. The existence of critical quenching speed is identified, which determines amorphous and crystalline phases in melting followed by quenching operation.
Rigel (2016)

Image processing algorithms implemented using custom hardware or FPGAs of can be orders-of-magnitude more energy efficient and performant than software. Unfortunately, converting an algorithm by hand to a hardware description language suitable for compilation on these platforms is frequently too time consuming to be practical. Recent work on hardware synthesis of high-level image processing languages demonstrated that a single-rate pipeline of stencil kernels can be synthesized into hardware with provably minimal buffering. Unfortunately, few advanced image processing or vision algorithms fit into this highly-restricted programming model. In this paper, we present Rigel, which takes pipelines specified in our new multi-rate architecture and lowers them to FPGA implementations. Our flexible multi-rate architecture supports pyramid image processing, sparse computations, and space-time implementation tradeoffs. We demonstrate depth from stereo, Lucas-Kanade, the SIFT descriptor, and a Gaussian pyramid running on two FPGA boards. Our system can synthesize hardware for FPGAs with up to 436 Megapixels/second throughput, and up to 297x faster runtime than a tablet-class ARM CPU.
Characterizing the Dynamic Behavior of Workload Execution in SVM systems (2004)

The overhead associated with software management of shared virtual memory (SVM) systems can seriously impact overall system performance. One way to remedy this situation is to design more efficient SVM consistency protocols. In this paper we study a number of parallel workload characteristics that can negatively impact the performance of SVM systems. We attempt to quantify the sources of performance loss in some parallel workloads. Our goal is to better understand these characteristics, enabling us to develop SVM protocols that can adjust to dynamics in workload behavior. This paper has three main contributions: i) we measure the contention for synchronization resources, showing how applications exhibit distinct phases during their execution, ii) we quantify the relationship between page size and fragmentation/false sharing while varying the sharing unit size, and iii) we study the synergies between the contention for synchronization resources and fragmentation/false sharing, providing hints for developing improved protocols.
Polymer-Supported Chiral Co(Salen) Complexes:  Synthetic Applications and Mechanistic Investigations in the Hydrolytic Kinetic Resolution of Terminal Epoxides (1999)

This paper describes the synthesis of polystyrene- and silica-bound chiral Co(salen) complexes and their application in asymmetric catalysis. A general method for the covalent attachment of salen complexes to both types of support has been devised, and the corresponding immobilized cobalt derivatives are shown to be efficient and highly enantioselective catalysts for the hydrolytic kinetic resolution (HKR) of terminal epoxides. These systems provide practical solutions to certain technical difficulties associated with the isolation of reaction products from the HKR. Removal of the supported catalyst by filtration and repeated recycling is demonstrated with no loss of reactivity or enantioselectivity. The enantioselective addition of phenols to terminal epoxides mediated by this catalyst system provides a facile, high-yielding synthesis of the corresponding enantioenriched aryl ethers. The immobilized catalysts have been adapted to a continuous flow process for the generation of reaction products in high yield and ee, requiring only very simple techniques for product purification. The mechanism by which these catalysts perform highly efficient and enantioselective epoxide ring opening has been addressed using a silica-bound Co(salen) complex. A dramatic corrrelation between the degree of catalyst site-isolation and reaction rate has been observed, consistent with a cooperative bimetallic mechanism in these reactions.
Ordered Whiskerlike Polyaniline Grown on the Surface of Mesoporous Carbon and Its Electrochemical Capacitance Performance (2006)

Supercapacitor electrode materials must exhibit high specific capacitance and high-rate charge–discharge ability. The ordered whiskerlike polyaniline (PANI) reported here, which was synthesized in situ on the surface of mesoporous carbon by a novel process, is demonstrated to have these properties thanks to its ordered nanometer-sized “thorns” (see figure) and the V-shaped nanopores between them. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2089/2006/c0445_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Standard and Increased-Dose BEACOPP Chemotherapy Compared with COPP-ABVD for Advanced Hodgkin's Disease (2003)

Increased-dose BEACOPP resulted in better tumor control and overall survival than did COPP-ABVD.
Efficient algorithms for robust feature matching (1997)

One of the basic building blocks in any point-based registration scheme involves matching feature points that are extracted from a sensed image to their counterparts in a reference image. This leads to the fundamental problem of point matching: Given two sets of points, find the (affine) transformation that transforms one point set so that its distance from the other point set is minimized. Because of measurement errors and the presence of outlying data points, it is important that the distance measure between the two point sets be robust to these effects. We measure distances using the partial Hausdorff distance. Point matching can be a computationally intensive task, and a number of of theoretical and applied approaches have been proposed for solving this problem. In this paper we present two algorithmic approaches to the point matching problem, in an attempt to reduce its computational complexity, while still providing a guarantee of the quality of the final match. Our first method ...
Los puertos, la actividad turistica y las pesqueras en el litoral del occidente de Mexico: Una visión de conjunto (1994)

espanolEn este trabajo se intenta presentar la situacion de los puertos, las pesquerias y el turismo en el litoral del Pacifico mexicano, para luego identificar los principales problemas que se presentan en el intento de lograr el desarrollo integral de las tres actividades mencionadas. EnglishThe aim of this paper is to describe the current situation of the harbors, the fisheries and the tourism activities on the Mexican Pacific coast in order to identify the main problems involved in the search for an integral development of the three activities.
O paradoxo de uma civilizaçao do trabalho sem emprego (1998)

La falta de trabajo en una sociedad que se basa precisamente en el trabajo productivo, da pie al autor para reflexionar sobre el propio concepto de trabajo a lo largo de la historia hasta llegar a Adam Smith, quien eleva el trabajo al estatuto teorico-social que aun hoy le es reconocido. La paradoja a la que se refiere el titulo se produce en el momento en que la reduccion del trabajo concebido, segun A. Smith, como «tiempo de trabajo», no redunda en menos horas de trabajo sino, pura y simplemente, en menos trabajadores, es decir, en desempleo y en el fin del sueno de la civilizacion del ocio.
Lymphocyte subsets differentially induce class II human leukocyte antigens on allogeneic microvascular endothelial cells. (1987)

Increased expression of major histocompatibility complex class II (Ia) antigens on vascular endothelium is a common observation in allografts undergoing acute rejection. This phenomenon is generally ascribed to the host immune response directed against graft alloantigens, but its cellular and molecular basis are incompletely understood. In the present study we show that constitutively Ia-negative human microvascular endothelial cells (EC) can be induced to express surface class II human leukocyte antigens shortly after exposure to allogeneic lymphocytes in vitro. CD16+ (natural killer) and CD8+ (cytotoxic/suppressor) lymphocytes were efficient in triggering Ia antigen expression by EC, whereas CD4+ (helper/inducer) lymphocytes induced EC Ia expression only if cultured in the presence of autologous monocytes. Binding of lymphocytes to EC was shown to be essential for the subsequent induction of EC Ia, and anti-CD18 (LFA-1) antibody, which blocks lymphocyte-EC adhesion, was the only antibody of a panel of antilymphocyte antibodies that completely blocked the induction of EC Ia. Antibodies to interferon-gamma, which is a potent inducer of EC Ia, and to the CD3 T cell-surface antigen partly inhibited the induction of EC Ia by T cells, but neither antibody had any effect on Ia induction mediated by CD16+ cells, suggesting that T cells and natural killer cells utilize different mechanisms to induce Ia on EC. When combined with data from other laboratories indicating that Ia+ but not Ia- EC stimulate allogeneic T cell proliferation and cytotoxicity, our results suggest that the binding of EC by lymphocyte subpopulations followed by the induction of Ia antigen may represent the initial stage of incompatible allograft rejection.
A pulse processing station (2002)

This is the first of two papers concerning the architecture, circuitry design and performance of a pulse processing system based on a digital signal processor. This multifunction system, implemented as a single PC module, incorporates a high performance 16-bit Pulse Height Analyser (PHA) a Multichannel Scaler (MCS), a Digital Oscilloscope (DSO) and also a Digital Pulse Processor (DPP). This paper presents the PHA architecture with emphasis on the baseline restorer and peak stretcher circuits. Differential nonlinearities (DNL) are corrected by a new implementation of the sliding scale technique and performance ranges from better than 2% (at 16-bit resolution) up to less than 0.2% for 12-bit operation. The DNL correction technique is assessed for different sliding-scale ranges.
Three-Fold Fewer Concussions in Youngest Hockey Players When Body Checking is Barred (2010)

Neurology Today reports on breaking news, issues, and trends in the practice and science of neurology, reaching more than 36,000 professionals. It delivers credible, up-to-the-minute, balanced, cutting-edge reporting and commentary for today's busy neurology professionals. Published in print twice a month with the latest developments and online-only coverage on NeurologyToday.com, Neurology Today also gives readers the inside track to key clinical and basic science advances from the AAN and its official journal, Neurology, as well as other peer-reviewed neurology and medical journals.
Lensless method of measuring Gaussian laser beam divergence (1978)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text Jon E. Sollid, Claude R. Phipps, Scott J. Thomas, and Edward J. McLellan, "Lensless method of measuring Gaussian laser beam divergence," Appl. Opt. 17, 3527-3529 (1978) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Coordinated antiinflammatory effects of interleukin 4: interleukin 4 suppresses interleukin 1 production but up-regulates gene expression and synthesis of interleukin 1 receptor antagonist. (1992)

Interleukin 1 receptor antagonist (IL-1ra), a naturally occurring polypeptide with amino acid sequence homology to interleukin 1 alpha (IL-1 alpha) and interleukin 1 beta (IL-1 beta), prevents Escherichia coli-induced shock and death. Both IL-1 and IL-1ra are produced by monocytes stimulated with lipopolysaccharide (LPS). Because interleukin 4 (IL-4) suppresses IL-1 production, we investigated whether IL-4 modulated IL-1ra synthesis in LPS-stimulated human peripheral blood mononuclear cells. IL-1 beta and IL-1ra were measured by specific RIAs. IL-4 alone (0.01-100 ng/ml) did not stimulate IL-1 beta synthesis but rather induced IL-1ra (4.82 +/- 0.94 ng/ml). LPS induced synthesis of both IL-1 beta (6.67 +/- 1.06 ng/ml) and IL-1ra (10.77 +/- 2.79 ng/ml). IL-4 suppressed LPS-induced IL-1 beta mRNA accumulation and synthesis. However, IL-4 acted synergistically with LPS in inducing IL-1ra. IL-4 enhanced LPS-induced IL-1ra mRNA accumulation 4-fold and IL-1ra protein synthesis nearly 2-fold. Moreover, IL-1ra mRNA levels were maximal after 6 hr of exposure to LPS but peaked within the first 3 hr in the presence of IL-4. IL-4 added as late as 12 hr after LPS stimulation still enhanced IL-1ra synthesis. In human peripheral blood mononuclear cells stimulated with IL-1 alpha, IL-4 markedly suppressed IL-1 beta production but enhanced IL-1ra synthesis greater than 2-fold. Because IL-4 favors synthesis of the natural antagonist IL-1ra over synthesis of the agonist IL-1, IL-4 may exert potent antiinflammatory effects on host responses to Gram-negative infections.
Learning Query and Document Relevance from a Web-scale Click Graph (2016)

Click-through logs over query-document pairs provide rich and valuable information for multiple tasks in information retrieval. This paper proposes a vector propagation algorithm on the click graph to learn vector representations for both queries and documents in the same semantic space. The proposed approach incorporates both click and content information, and the produced vector representations can directly improve ranking performance for queries and documents that have been observed in the click log. For new queries and documents that are not in the click log, we propose a two-step framework to generate the vector representation, which significantly improves the coverage of our vectors while maintaining the high quality. Experiments on Web-scale search logs from a major commercial search engine demonstrate the effectiveness and scalability of the proposed method. Evaluation results show that NDCG scores are significantly improved against multiple baselines by using the proposed method both as a ranking model and as a feature in a learning-to-rank framework.
Controlled Polymerization in Polar Solvents to Ultrahigh Molecular Weight Polyethylene (2018)

Novel complexes based on 2,4,8-triarylnaphthylamine [[(2,4-{3,5-(CF<sub>3</sub>)<sub>2</sub>C<sub>6</sub>H<sub>3</sub>}<sub>2</sub>-8-(3,5-R<sub>2</sub>C<sub>6</sub>H<sub>3</sub>)-C<sub>10</sub>H<sub>4</sub>)-N═C(H)-{3-(9-anthryl)-2-O-C<sub>6</sub>H<sub>3</sub>}-κ<sup>2</sup>-N,O]Ni(CH<sub>3</sub>)(pyridine)] (4-Py, R = Me; 5-Py, R = CF<sub>3</sub>) were synthesized from 8-arylnaphthylamines which can be generated via selective lithiation, borylation, and coupling in a one-pot procedure. Due to their living characteristics in ethylene polymerization and the particularly low propensity of 5-Py for β-H elimination as reflected by a high linearity even at elevated polymerization temperatures of 60 °C, ultrahigh molecular weight polyethylene (UHMWPE) is formed in polar organic solvents (THF, diethyl ether) as a reaction medium in a controlled polymerization ( M<sub>w</sub>/ M<sub>n</sub> = 1.2 at M<sub>n</sub> = 1.1 × 10<sup>6</sup> g mol<sup>-1</sup>).
The Effect of Sleep Fragmentation on Daytime Function (2002)

It is clear from this literature that fragmented sleep is less restorative than consolidated sleep, and leads to sleepiness-related daytime impairment. The optimal approach to the quantification of sleep fragmentation continues to be debated. Modest and erratic correlations between measures of sleepiness and traditional measures of EEG arousals have pushed investigators to try and find more sensitive measures of sleep fragmentation. Simply correlating various measures of sleep fragmentation with a measure of sleepiness has significant limitations. Since sleep fragmentation is not the only factor affecting daytime sleepiness, these correlations can be misleading. For example, a subject with severely fragmented sleep will show elevated sleepiness during the day. However, the overall correlation may be reduced because lack of fragmented sleep does not guarantee that the level of sleepiness will be low. Multivariate statistical modeling is needed to account for sources of variance simultaneously in the prediction of daytime sleepiness. In this way it may be possible to identify the optimal definition of sleep fragmentation. More studies are needed that evaluate "sub-cortical" arousals, EEG arousals, and daytime function simultaneously. Ideally, clarification of these measurement issues will lead to an improved understanding of sleep structure and the mechanism through which sleep fragmentation impacts daytime function.
A wire-sheath system for MR-guided biopsy and drainage: laboratory studies and experience in 10 patients (1988)

On the basis of laboratory experiments, we devised a wire-sheath system for MR-guided biopsy and drainage and then evaluated that system in 10 patients. The localizing system consisted of a 20-gauge plastic sheath into which a stainless-steel alloy wire had been inserted. In laboratory studies, we compared this wire-sheath assembly with other materials to determine its optimal visualization on MR images. We then used the same wire-sheath system to perform 16 procedures (in 10 patients), including six biopsies, five diagnostic fluid aspirations, and five catheter drainages of infected and noninfected fluid collections. The laboratory results showed that the wire-sheath assembly cast a 7-mm artifact, was visualized well on all pulse sequences, and was safe within the magnet (minimal attraction). The assembly was visualized well in each patient and provided adequate localization. MR-guided biopsy and drainage can be performed with high-resolution detail by using this wire-sheath system. Potential uses of this system include (1) treatment of lesions that can be seen on MR images only (or that can be seen to significantly better advantage on MR images than on sonograms or CT scans), and (2) treatment of patients in whom avoidance of the radiation delivered by CT is imperative.
The Intersection of Sociology of Scientific Knowledge (SSK) and Law: Some Themes and Policy Reflections (2002)

The following article provides a brief sketch of some important themes that can be drawn from studies which have investigated law/science interactions from a Sociology of Scientific Knowledge (SSK) perspective and notes some of the policy ramifications of such studies. SSK studies can be characterised by their analytical concern with linking the content of scientific knowledge and the practices of scientists to the social contexts in which scientific knowledge claims are produced and evaluated and their rejection of the idea that science is something that can be defined by its unique method and social norms (Mulkay 1979, Collins &amp; Pinch 1993, Lynch &amp; Bogen 1997). Many SSK/law studies have focused on controversial areas of science and law such as toxic torts, forensic science and risk and environmental regulation. The brief overview provided below will identify some important, recurrent conceptual themes rather than provide an exhaustive bibliographic survey.