gebhart/patrepeval huggingface dataset:
Machine type communications in 3GPP networks: potential, challenges, and solutions (2012)

With a wide range of potential applications, Machine Type Communication (MTC) or Machine to Machine (M2M) communication is gaining a tremendous interest among mobile network operators, equipment vendors, MTC specialist companies, and research bodies. To facilitate convergence among these different stakeholders, different standardization groups started working on MTC. This article introduces briefly some of the relevant activities, with a focus on those related to the 3rd Generation Partnership Project (3GPP). The article focuses on two important aspects of MTC devices, currently discussed in 3GPP as part of its Release 10. They are subscription control and network congestion/overload control. For the latter, a new solution based on bulk signaling handling is proposed.
Canal dehiscence (2010)

Superior semicircular canal dehiscence is now a well-established entity in the medical literature. Surgical repair is effective at relieving patients' vestibular symptoms. Lateral semicircular canal dehiscence is usually associated with chronic otitis media. Posterior semicircular canal dehiscence is a rare entity, with similar clinical presentations and treatment options as the other canal dehiscences.
A 2 GHz Fractional-N Digital PLL with 1b Noise Shaping $\Delta\Sigma$ TDC (2012)

This paper presents a low-power noise-shaping ΔΣ time-to-digital converter (TDC) and its application to a fractional-N digital PLL. With a simple structure of single-delay-stage Δ modulator followed by a charge pump based Σ modulator, a wide range of TDC input is converted to ΔΣ modulated single bit stream without loss of signal information. The ΔΣ architecture of TDC effectively improves the conversion performance of linearity and resolution while handling a large input range due to the operation of the dual-modulus divider. In addition, with a downscaling of the amount of the single delay in Δ modulator, the signal and noise transfer characteristics of TDC can be profiled to suppress the out-band noises at the input to the loop filter, resulting in easy filtering without any extra noise cancelling scheme. The DPLL is fabricated with a 0.13 μm CMOS technology. With a loop bandwidth of 1 MHz, DPLL shows an in-band phase noise of - 107 dBc/Hz at 500 kHz offset and an out-of-band phase noise of -118.5 dBc/Hz at 3 MHz offset. The TDC consumes 1 mA.
CDE: using system call interposition to automatically create portable software packages (2011)

It can be painfully hard to take software that runs on one person’s machine and get it to run on another machine. Online forums and mailing lists are filled with discussions of users ’ troubles with compiling, installing, and configuring software and their myriad of dependencies. To eliminate this dependency problem, we created a system called CDE that uses system call interposition to monitor the execution of x86-Linux programs and package up the Code, Data, and Environment required to run them on other x86-Linux machines. Creating a CDE package is completely automatic, and running programs within a package requires no installation, configuration, or root permissions. Hundreds of people in both academia and industry have used CDE to distribute software, demo prototypes, make their scientific experiments reproducible, run software natively on older Linux distributions, and deploy experiments to compute clusters. 1
High accuracy jitter measurement using cyclic pulse width modulation structure (2005)

For high-speed circuit testing, traditional ways are not enough in measuring the clock jitter. The probe's loading effect would distort the tested clock signal and change the measurement result. Even some BIST techniques can release this problem. There is still a conflict between the circuit area and the timing resolution in the existing BIST techniques. The cyclic pulse width modulation structure is used to release this problem. The hardware overhead problem is released and the demanded resolution also can be reached. Furthermore, the effect of the PVTL is also released. The simulation result is based on TSMC 0.25/spl mu/m CMOS process. The selectable resolution is from 9ps to 20ps and the area is 0.039mm/sup 2/.
Inhibitors of Human and Rat Testes Microsomal 17 β-Hydroxysteroid Dehydrogenase (17β-HSD) as Potential Agents for Prostatic Cancer (2001)

In a screening programme for inhibitors of human testis 17beta-hydroxysteroid dehydrogenase (17beta-HSD type 3), as potential agents for the treatment of hormone-dependent prostatic cancer, we have used crude human testis microsomal 17beta-hydroxysteroid dehydrogenase as a convenient source of the enzyme. Crude human enzyme was shown to have a similar substrate profile to recombinant Type 3 17beta-HSD from the same source as determined by the low Km/Vmax ratio for the reduction of androstenedione compared to the oxidation of testosterone, and a low level of activity in reduction of oestrone. Screening of a wide range of compounds of different structural types as potential inhibitors of the microsomal enzyme in the reduction step revealed that certain p-benzoquinones and flavones/isoflavones were potent inhibitors of the enzyme, diphenyl-p-benzoquinone (2.7 microM), phenyl-p-benzoquinone (5.7 microM), 7-hydroxyflavone (9.0 microM), baicalein (9.3 microM) and biochanin A (10.8 microM). Some structure-activity relationships within the flavone/isoflavone series are discussed. Studies with rat testis microsomal 17beta-HSD showed that it differed from the human enzyme mainly in its greater ability to accept oestrone as substrate and the pH-optimum for oxidation of testosterone. It was found to be much less sensitive to inhibition by the compounds studied so negating it use as a more readily available tissue for the screening of potential inhibitors.
Skin Lesion Analysis By Multi-Target Deep Neural Networks (2018)

Automatic skin lesion analysis involves two critical steps: lesion segmentation and lesion classification. In this work, we propose a novel multi-target deep convolutional neural network (DCNN) to simultaneously tackle the problem of segmentation and classification. Based on U-Net and GoogleNet, a single model is constructed with three different targets of both lesion segmentation and two independent binary lesion classifications (i.e., melanoma detection and seborrheic keratosis identification), aiming to explore the differences and commonalities over different target models. We conduct experiments on dermoscopic images from the International Skin Imaging Collaboration (ISIC) 2017 Challenge. Results of our multi-target DCNN model demonstrates superiority over single model with one target only (such as U-net or GoogleNet), indicating its learning efficiency and potential for application in automatic skin lesion diagnosis. To the best of our knowledge, this work is the first demonstration for a single end-to-end deep neural network model that simultaneously handle both segmentation and classification in the field of skin lesion analysis.
Performance and comparability of laboratory methods for measuring ferritin concentrations in human serum or plasma: A systematic review and meta-analysis (2018)

The laboratory methods most used to determine ferritin concentrations have comparable accuracy and performance. Registered in PROSPERO CRD42016036222.
Current development in genetic engineering strategies of Bacillus species (2014)

The complete sequencing and annotation of the genomes of industrially-important Bacillus species has enhanced our understanding of their properties, and allowed advances in genetic manipulations in other Bacillus species. Post-genomic studies require simple and highly efficient tools to enable genetic manipulation. Here, we summarize the recent progress in genetic engineering strategies for Bacillus species. We review the available genetic tools that have been developed in Bacillus species, as well as methods developed in other species that may also be applicable in Bacillus. Furthermore, we address the limitations and challenges of the existing methods, and discuss the future research prospects in developing novel and useful tools for genetic modification of Bacillus species.
Left ventricular lead stabilization to retain cardiac resynchronization therapy at long term: when is it advisable? (2013)

Coronary vein anatomy may assist decision making about the need for LV lead stabilization, and the choice of tools during the implanting procedure to ensure effective CRT delivery at long term.
Statistical Evaluation of Minimum Zone Method in Coordinate Metrology. (1998)

本論文では, 座標計測における最小領域法の統計的評価の方法を提案した.まず, 測定値の範囲の統計的推定方法として, 順位が1の測定点の分布を統計的に求めた.この分布を利用することで測定点の範囲と測定点の数の関係を定式化することができた.この範囲は, 平面度, 真円度などにも同様の考え方で適応できると考えている.さらに, 測定点の範囲は測定点の確率密度関数の上限, 下限もしくはすそ野の形によって決定されることを示した.これによれば, 最小領域法による形状精度の決定にはかなり多くの測定点が必要になることを明らかにした.つぎに直線形体の傾きパラメータの性質について検討を行った.このパラメータの分布は, 順位1と2の測定点の分布によって推定できることを示した.しかし, パラメータの分布を推定することはかなり難しく, 測定値との分布などとの関係は今後の課題となった.これは, 平面の傾き, 円の直径や中心位置などの検討に対しても同様の問題となる.以上のような検討により, 従来あまり行われていなかった最小領域法に対する統計的評価の基本的な方法を定式化し, 以下の結論が得られた.(1) 測定値の範囲は, 測定点を大きさの順序で並べた測定点の順位および順位1の測定点の分布によってその性質を示すことができた.(2) 最小領域法で求めた, 直線形体の傾きのパラメータの統計的性質を推定し, 順位1の測定点の標準偏差によって, 傾きパラメータの範囲を表した.
Real-Time Stereo Mosaicing Using Feature Tracking (2011)

Real-time creation of video mosaics needs fast and accurate motion computation. While most mosaicing methods can use 2D image motion, the creation of multi view stereo mosaics needs more accurate 3D motion computation. Fast and accurate computation of 3D motion is challenging in the case of unstabilized cameras moving in 3D scenes, which is always the case when stereo mosaics are used. Efficient blending of the mosaic strip is also essential. Most cases of stereo mosaicing satisfy the assumption of limited camera motion, with no forward motion and no change in internal parameters. Under these assumptions uniform sideways motion creates straight epipolar lines. When the 3D motion is computed correctly, images can be aligned in space-time volume to give straight epipolar lines, a method which is depth invariant. We propose to align the video sequence in a space-time volume based on efficient feature tracking, and in this paper we used Kernel Tracking. Computation is fast as the motion in computed only for a few regions of the image, yet giving accurate 3D motion. This computation is faster and more accurate than the previously used direct approach. We also present "Barcode Blending", a new approach for using pyramid blending in video mosaics, which is very efficient. Barcode Blending overcomes the complexity of building pyramids for multiple narrow strips, combining all strips in a single blending step. The entire stereo mosaicing process is highly efficient in computation and in memory, and can be performed on mobile devices.
Breast Cancer Risk Associated With Reproductive Factors and Breast Parenchymal Patterns (1984)

In a population-based study of 23,511 women 50-67 years of age at the time of first screening, a striking relationship was found between parity and age at first childbirth, on the one hand, and two radiologic aspects of breast parenchymal pattern (dysplasia and prominent duct pattern), on the other. These relationships appeared to be causal.
Binding of epidermal growth factor and insulin‐like growth‐factor I in renal carcinoma and adjacent normal kidney tissue (1989)

The binding of epidermal growth factor (EGF) and insulin-like growth factor I (IGF-I) to cell membranes was determined in 14 renal cancers and in 13 normal kidney tissues adjacent to the tumors. The soluble 34K IGF binding protein (34K IGF-BP) content and the phosphotyrosyl-protein phosphatase activity in renal cancer tissue and adjacent normal tissue were also determined. The specific EGF receptor binding in renal cancers was 12.7 +/- 2.5% (mean +/- SEM) as compared to 2.6 +/- 0.2% (mean +/- SEM) in normal tissues (p less than 0.01). Phosphotyrosyl-protein phosphatase activity in renal cancer tissue was less than half of that observed in normal renal tissue (p less than 0.01). The highest IGF-I binding was observed in 5 renal cancers although no consistent differences between IGF-I binding to tumor and normal tissues were observed. Both EGF and IGF binding to kidney tissue were higher than binding to gastro-intestinal tissue irrespective of whether normal or malignant tissues were compared. All normal kidney tissues and 7 of 8 kidney tumors contained measurable amounts of 34K IGF-BP as determined by RIA and the cross-linking technique. In 2 tumor tissue samples the 34K IGF-BP content was increased 8- and 15-fold over that seen in adjacent normal kidney tissue, whereas in the 6 other renal cancers the 34K IGF-BP was similar to that observed in normal kidney tissue.
Ideation Variety in Mechanical Design: Examining the Effects of Cognitive Style and Design Heuristics (2015)

This paper examines ideation variety as a measure of the extent to which a design solution space has been explored. We investigated one cognitive factor (cognitive style) and one cognitive intervention (Design Heuristics cards) and their relationships with students’ ideation variety, both actual and perceived. Cognitive style was measured using the Kirton Adaption-Innovation inventory (KAI), while variety scores were computed using the metrics of Nelson et al. [18] and Shah et al. [20]; an adapted form of these metrics was also explored. A group of 132 sophomore mechanical engineering students generated ideas for two design problems (one with and one without Design Heuristics cards). They sketched and described their conceptual solutions in words and assessed the variety of their solutions after ideation. Linear statistical techniques were applied to explore the relationships among the variety scores, students’ self-assessments of variety, cognitive style, quantity of ideas, and the presence of the Design Heuristics intervention. Our results show statistically significant correlations between students’ perceived variety and their variety performance, and between cognitive style and both variety performance and student perceptions.
Demonstration of speed enhancements on an industrial circuit through application of non-zero clock skew scheduling (2002)

A demonstration of the application of non-zero clock skew scheduling to enhance the speed characteristics of several functional unit blocks in a high performance processor is presented. It is shown that non-zero clock skew scheduling can improve circuit performance while relaxing the strict timing constraints of the critical data paths within a high speed system. A software tool implementing a non-zero clock skew scheduling algorithm is described together with a methodology that generates the required clock signal delays by replacing clock buffers from predesigned cell libraries. Timing margin improvements of up to 18% are achieved through the application of non-zero clock skew scheduling in certain functional blocks of an industrial high performance microprocessor.
Isolation of twenty low stutter di‐ and tetranucleotide microsatellites for population analyses of walleye pollock and other gadoids (2000)

Fourteen tetra‐ and six dinucleotide microsatellites, which exhibit minimal stuttering following amplification via PCR were developed from walleye pollock Theragra chalcogramma . Most of these loci were isolated from a library enriched for tetranucleotide microsatellites by hybridization of genomic DNA to (gata) 7 oligonucleotides bound to streptavidin‐coated paramagnetic beads. The average heterozygosity of these loci is ∼80%, and ranges from 53–95%. Mendelian inheritance was confirmed in five families, each consisting of a minimum of 10 or more offspring. Primer sets for all 20 loci were also evaluated in Arctic cod Boreogadus saida , Pacific cod Gadus macrocephalus , Pacific tomcod Microgadus proximus , sa.ron cod Eleginus gracilis , Pacific hake Merluccius productus , Atlantic cod Gadus morhua , haddock Melanogrammus aeglefinus , blue whiting Micromesistius poutassou , and European hake Merluccius merluccius . In each of these species, 3–19 primer sets amplified variable microsatellite loci. These loci, which exhibit little stutter and moderate to high variability, should be useful population markers in pollock and other gadoid fishes.
Software Documents: Concepts and Tools. (1994)

In this paper, we review software development as a document-based process, with the capture of a full but ideal development history as the assumed purpose of the documents concerned. We identify generic requirements for perusal, editing and verification of such documents, and illustrate how these requirements could be met in a software development environment based on current interaction technology. Finally, we propose a generic environment architecture for implementation of the facilities concerned, and outline how our own research work has addressed some of the requirements of this architecture.
Comparison of approaches for augmenting the serologic response to the individually specific methylcholanthrene-induced sarcoma-Meth A: pretreatment with cyclophosphamide is most effective. (1983)

We have previously reported the production of antisera against a highly restricted antigen expressed on the BALB/c sarcoma Meth A. Because induction of the antibody required many vaccinations with irradiated and unirradiated Meth A cells over a prolonged period, we have investigated methods of improving the efficiency of producing Meth A antibody in BALB/c mice. Three general approaches were used: immunizing with irradiated Meth A cells mixed with adjuvants, immunizing with irradiated Meth A cells modified by treatment with chemicals, or administration of tumor cell vaccines in conjunction with low dose cyclophosphamide. These vaccine preparations were injected subcutaneously into groups of BALB/c mice five to six times at 2-wk intervals. Sera from all mice were screened for reactivity to Meth A by complement-dependent cytotoxicity, protein A, and mixed hemadsorption assays. Twenty-three vaccine preparations containing adjuvants or modified cells were tested in individual groups of mice. Mice in some groups receiving adjuvants and in all groups receiving modified cells produced antibody, but only after four to six vaccinations. In contrast, nine of the 14 mice immunized with irradiated Meth A cells (unmodified and without adjuvant) in conjunction with 10 or 100 mg/kg body weight of cyclophosphamide, and all nine of the mice receiving 25 mg/kg cyclophosphamide made Meth A antibodies after only one or two vaccinations. The titer of antibodies produced after one treatment with cyclophosphamide and irradiated Meth A cells was at least as high as that achieved after five or six vaccinations in our other trials. The specificity of these antibodies for the Meth A antigen was established by absorption analysis. We conclude that treatment with cyclophosphamide before vaccination is highly effective in augmenting the humoral immune response to the Meth A antigen.
Interpreting the Latent Space of GANs for Semantic Face Editing (2019)

Despite the recent advance of Generative Adversarial Networks (GANs) in high-fidelity image synthesis, there lacks enough understanding of how GANs are able to map a latent code sampled from a random distribution to a photo-realistic image. Previous work assumes the latent space learned by GANs follows a distributed representation but observes the vector arithmetic phenomenon. In this work, we propose a novel framework, called InterFaceGAN, for semantic face editing by interpreting the latent semantics learned by GANs. In this framework, we conduct a detailed study on how different semantics are encoded in the latent space of GANs for face synthesis. We find that the latent code of well-trained generative models actually learns a disentangled representation after linear transformations. We explore the disentanglement between various semantics and manage to decouple some entangled semantics with subspace projection, leading to more precise control of facial attributes. Besides manipulating gender, age, expression, and the presence of eyeglasses, we can even vary the face pose as well as fix the artifacts accidentally generated by GAN models. The proposed method is further applied to achieve real image manipulation when combined with GAN inversion methods or some encoder-involved models. Extensive results suggest that learning to synthesize faces spontaneously brings a disentangled and controllable facial attribute representation.
Rapid subpicomole electrochemical enzyme immunoassay for immunoglobulin G (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRapid subpicomole electrochemical enzyme immunoassay for immunoglobulin GW. Uditha de Alwis and George S. WilsonCite this: Anal. Chem. 1985, 57, 14, 2754–2756Publication Date (Print):December 1, 1985Publication History Published online1 May 2002Published inissue 1 December 1985https://pubs.acs.org/doi/10.1021/ac00291a004https://doi.org/10.1021/ac00291a004research-articleACS PublicationsRequest reuse permissionsArticle Views120Altmetric-Citations82LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The Conformation of Informational Macromolecules (2002)

This chapter contains sections titled: Proteins Nucleic Acids Conclusion
High-content single-cell combinatorial indexing (2021)

Abstract Single-cell genomics assays have emerged as a dominant platform for interrogating complex biological systems. Methods to capture various properties at the single-cell level typically suffer a tradeoff between cell count and information content, which is defined by the number of unique and usable reads acquired per cell. We and others have described workflows that utilize single-cell combinatorial indexing (sci) 1 , leveraging transposase-based library construction 2 to assess a variety of genomic properties in high throughput; however, these techniques often produce sparse coverage for the property of interest. Here, we describe a novel adaptor-switching strategy, ‘s3’, capable of producing one-to-two order-of-magnitude improvements in usable reads obtained per cell for chromatin accessibility (s3-ATAC), whole genome sequencing (s3-WGS), and whole genome plus chromatin conformation (s3-GCC), while retaining the same high-throughput capabilities of predecessor ‘sci’ technologies. We apply s3 to produce high-coverage single-cell ATAC-seq profiles of mouse brain and human cortex tissue; and whole genome and chromatin contact maps for two low-passage patient-derived cell lines from a primary pancreatic tumor.
Survey of WLAN Fingerprinting Positioning System (2013)

The increasing demand for indoor location based services has motivated the development of various indoor positioning methods. Among them, fingerprinting based positioning system in wireless local area network (WLAN) has been paid more attentions due to its cost effectiveness and relatively high accuracy. This paper investigates various optimization techniques for WLAN fingerprinting positioning comprehensively. The fingerprinting positioning comprises five major steps: Radio Map construction, location clustering, feature extraction, location estimation and tracking. The optimization techniques in these five steps are discussed and finally the future trends are presented.