gebhart/patrepeval huggingface dataset:
IMPACT OF VIRUS INFECTION ON HOST CELL PROTEIN SYNTHESIS (1987)

There is good evidence that a variety of viruses encode functions that inhibit activation of either ribonuclease L or the Pl/eIF-2 alpha kinase. In general, this capability is evident among viruses that maintain long-term active or latent infections, and must therefore deal with interferon-induced antiviral responses of their hosts.
Generation of Patterns With External Conditions for the Game of Go (2001)

. Patterns databases are used to improve search in games. We have generated pattern databases for the game of Go. The generated patterns are associated to conditions external to the pattern. This enables the pattern to cover much more positions, but it leads to new problems for pattern generation. We explain how we have managed to solve these problems. We believe that patterns associated to external conditions can be useful in other games. 1 INTRODUCTION In this paper, we explain how to generate pattern-based knowledge associated to external conditions for the game of Go. This approach has good properties for the game of Go. Tsume-Go is an important problem of the game of Go, it consists in finding if a group is alive (the opponent cannot remove it) or dead. Patterns have also been generated for connections and removing of stones. In the second section, we relate our work to similar works in other games and especially Chess and Checkers, then explain why associating external conditi...
Phylogenomics and Analysis of Shared Genes Suggest a Single Transition to Mutualism in Wolbachia of Nematodes (2013)

Wolbachia, endosymbiotic bacteria of the order Rickettsiales, are widespread in arthropods but also present in nematodes. In arthropods, A and B supergroup Wolbachia are generally associated with distortion of host reproduction. In filarial nematodes, including some human parasites, multiple lines of experimental evidence indicate that C and D supergroup Wolbachia are essential for the survival of the host, and here the symbiotic relationship is considered mutualistic. The origin of this mutualistic endosymbiosis is of interest for both basic and applied reasons: How does a parasite become a mutualist? Could intervention in the mutualism aid in treatment of human disease? Correct rooting and high-quality resolution of Wolbachia relationships are required to resolve this question. However, because of the large genetic distance between Wolbachia and the nearest outgroups, and the limited number of genomes so far available for large-scale analyses, current phylogenies do not provide robust answers. We therefore sequenced the genome of the D supergroup Wolbachia endosymbiont of Litomosoides sigmodontis, revisited the selection of loci for phylogenomic analyses, and performed a phylogenomic analysis including available complete genomes (from isolates in supergroups A, B, C, and D). Using 90 orthologous genes with reliable phylogenetic signals, we obtained a robust phylogenetic reconstruction, including a highly supported root to the Wolbachia phylogeny between a (A + B) clade and a (C + D) clade. Although we currently lack data from several Wolbachia supergroups, notably F, our analysis supports a model wherein the putatively mutualist endosymbiotic relationship between Wolbachia and nematodes originated from a single transition event.
Drugs affecting the central nervous system (2023)

Abstract This chapter contains seven True/False Multiple-Choice Questions (MCQs) and seven Single Best Answers (SBAs) on drugs affecting the central nervous system. These high-quality pharmacology practice questions are tailored to the Fellowship of the Royal College of Anaesthetists (FRCA), the European Diploma in Intensive Care Medicine (EDIC), and Fellowship of the Faculty of Intensive Care Medicine (FFICM) examinations. Providing a mock exam experience, structured questions and answers are accompanied by detailed explanations, cross-references to Drugs in Anaesthesia and Intensive Care (5th edition), and further reading to wider resources. Written by consultants and experienced trainees, this chapter tests the reader’s knowledge of drugs that affect the central nervous system.
A framework for statistical data mining with summary tables (2003)

Presents a framework for statistical data mining using summary tables. A set of operators is proposed for common data mining tasks, such as summarization, association, classification and clustering, as well as for basic statistical analysis, such as hypothesis testing, estimation and regression, which can help explore knowledge. The operators enable users to explore a variety of knowledge effectively and yet require users to have little statistical knowledge. Summary tables, which store basic information about groups of tuples of the underlying relations, are constructed to speed up the data mining process. The summary tables are incrementally updatable and are able to support a variety of data mining and statistical analysis tasks. The operators, together with the uses of the summary tables, can make interactive data mining flexible, effective, and perhaps instantaneous.
<title>Model of foveal visual preprocessor</title> (1995)

A neural network model of the foveal visual preprocessor (FVP) based on a non-uniform representation of the vision field from the center to the periphery has been developed. The properties of foveal neural network and the results of computer simulation and analytical study of the model are considered. The dependence of a sensory tuning of FVP elements on the FVP and moving stimulus parameters is studied. A possible development of a foveal visual sensor on the base of the results obtained is discussed.
Fitting of iso-surfaces using superquadrics and free-form deformations (2002)

Recovery of 3D data with simple parametric models has been the subject of many studies over the last ten years. Many have used the notion of superquadrics introduced for graphics by Barr (1981). Different improvements were introduced to make the model a better representation of the data (Boult and Gross, 1987; Ferrie et al., 1989; Solina and Bajcsy 1990; Terzopoulos and Metaxas, 1991). The authors describe a two-steps method to fit a parametric deformable surface to 3D points. They suppose that a 3D image has been segmented to get a set of 3D points. The first step consists in their version of a superquadric fit with global tapering, similar to the method proposed by Boult and Gross (1987). The authors then make use of the technique of free-form deformations, as introduced by Sederberg and Parry (1986) in computer graphics. They present experimental results with synthetic and real 3D medical images.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Application of the Contact Pressure Display (CPD) Method to Tire Mechanics (1985)

<div class="htmlview paragraph">The CPD (Contact Pressure Display) method allows simultaneous recording of pressure distribution between a flexible body and a quasi-rigid one. The light reflected from a special sandwich plate produces an interference pattern function of the contact pressure distribution. The method, used until now for determining human foot-ground pressure patt rn, during gait, was adopted to analyze several passenger car tires. Processing the measurements through a simple technique allows the determination of realistic tire contact pressure diagrams, taking into account the influence of the tread pattern. Several results are presented. The method may yield important data to be used as boundary conditions in numerical models of tire behavior, for static and dynamic tire design. It seems that it is possible to use the CPD method in detecting tire defects, by analysing the differences in pressure distribution. Other possible utilizations are non-destructive road test stations for truck tires, non-destructive evaluation of racing car tires.</div>
Usefulness of the nude mouse model in mesothelioma based on a direct patient–xenograft comparison (1991)

A patient with malignant mesothelioma experienced tumor recurrence 3 months after pleuropneumonectomy. Samples of the tumor were transplanted into nude mice to assess chemosensitivity. There was close concordance between the results in xenografts and the clinical outcome in this patient. Both mitomycin and to a lesser extent cisplatin were effective as single agents against the nude mouse xenografts, and the combination of these two drugs produced a complete response both in the patient and in the xenografts. The patient survived 18 months from onset of chemotherapy and 24 months from diagnosis. The duration of clinical complete response to chemotherapy was 14 months, despite the fact that mitomycin, the most effective agent against the xenografts, was discontinued after only two cycles because the patient developed pulmonary toxicity. This direct patient-xenograft correlation further validates the usefulness of the nude mouse model in the search for effective therapies for malignant mesothelioma, a tumor characterized by frequent refractoriness to most available agents.
Effect of high temperature and interface treatments on photoluminescence from InGaN/GaN multiple quantum wells with green light emissions (2003)

InGaN/GaN multiple quantum wells (MQWs) with emission peaks in the green light region were grown by metalorganic chemical vapor deposition. Photoluminescence (PL) measurements on these samples showed extra peaks in the spectrum beside the green emission due to reactor temperature ramping up to 1000 °C after the MQWs growth. It was found that growth interruption at the upper interface of MQWs combining with interface treatment by H2 flow could eliminate these extra peaks. Our analysis of the PL spectra suggested that these extra emission peaks originate due to the occurrence of In segregation in the upper part of the quantum wells induced by partial strain relaxation in the processes of high temperature treatment, and the interface treatment with H2 flow can suppress this phase separation phenomenon.
Catalytic Properties of Metal Sulfates Supported on γ-Al2O3 in the Liquid-Phase Isopropylation of <i>m</i>-Cresol with Propylene (1976)

Abstract γ-Al2O3 was impregnated with various metal sulfates, calcined, and used as catalysts in the liquid-phase isopropylation of m-cresol at 250–300 °C, with the propylene pressure in the range from 15 to 79 kg/cm2. The catalytic activities of the sulfates were in the order: Al2(SO4)3&gt;ZnSO4≈NiSO4&gt;FeSO4&gt;CuSO4&gt;Li2SO4≈ none≈CaSO4&gt;Na2SO4. The order of the selectivity Φ for ortho-isopropylation over para-isopropylation was opposite to that of the catalytic activity. FeSO4/Al2O3 catalysts resulted in the best Φ value and fairly high activity, which were independent of the calcination temperature over the range of 300–500 °C. The formation of Brønsted acidic sites with 1≤H0≤3 as catalytically-active sites was estimated for the FeSO4/Al2O3 and ZnSO4/Al2O3 catalysts.
Fluorescent Inhibitors for IspF, an Enzyme in the Non‐Mevalonate Pathway for Isoprenoid Biosynthesis and a Potential Target for Antimalarial Therapy (2006)

Designed inhibitors (like 1) of IspF, a key enzyme in the non-mevalonate pathway for terpene biosynthesis and a potential antimalarial target, were synthesized and evaluated. Since fluorescent probes were introduced in these ligands, their affinity towards IspF from E. coli could be determined by fluorescence titrations. The binding modes of two ligands in ternary complexes with IspF and a ZnII ion were clarified by X-ray analysis.
TESSO: An analytical tool for characterizing aggregate interference and enabling spatial spectrum sharing (2017)

Radio propagation models play a crucial role in realizing effective spectrum sharing. Unlike propagation models that do not use the exact details of terrain, terrain-based propagation models are effective in identifying spatial spectrum sharing opportunities for the secondary users (SUs) around an incumbent user (IU). Unfortunately, terrain-based propagation models, such as the Irregular Terrain Model (ITM) in point-to-point (PTP) mode, are computationally expensive, and they require precise geo-locations of the SUs. Such requirements render them challenging, if not impractical, to implement in real-time applications, such as geolocation database (GDB)-driven spectrum sharing. To address this problem, we propose a pragmatic approach called Tool for Enabling Spatial Spectrum Sharing Opportunities (TESSO). TESSO characterizes the aggregate interference caused by the SUs and identifies spatial spectrum sharing opportunities effectively. It is computationally efficient, and does not require precise geo-locations of the SUs. Our results show that TESSO provides the same level of interference protection guarantee to the IU as that offered by the terrain-based models. TESSO can be implemented in GDB-driven spectrum sharing ecosystems for effectively exploiting spatial spectrum sharing opportunities.
Identification and control of a non-minimum phase flexible dynamical system using neural networks (2002)

In this paper, a two-degree-of freedom control system for motion control of a flexible system is presented. The two-degree-of-freedom control system consists of a feedback controller and feedforward controller. The feedback controller is designed based on Lyapunov's direct method while the feedforward controller is designed based on the inverse dynamics. Several computational approaches are compared for making an inverse dynamics model of a control object. Three different approaches are shown to acquire the inverse dynamics model: a mathematical model based on the Laplace transformation method; a system identification model based on ARX model; and a neural network identification model. Experimental and numerical results for the tracking control of a self-sensing piezo-polymer actuator are presented and verify that the proposed control system is effective for controlling flexible dynamical systems.
Coexistence measurements and analysis of IEEE 802.15.4 with Wi-Fi and bluetooth for vehicle networks (2012)

This paper gives an overview of the channel access methods of three wireless technologies that are likely to be used in the environment of vehicle networks: IEEE 802.15.4, IEEE 802.11 and Bluetooth. Researching the coexistence of IEEE 802.15.4 with IEEE 802.11 and Bluetooth, results of experiments conducted in a radio frequency anechoic chamber are presented. The power densities of the technologies on a single IEEE 802.15.4 channel are compared. It is shown that the pure existence of an IEEE 802.11 access point leads to collisions due to different timing scales. Furthermore, the packet drop rate caused by Bluetooth is analyzed and an estimation formula for it is given.
Organic Synthesis Utilizing Thiazolidine and the Related Heterocycles (1984)

A highly selective asymmetric induction into symmetrical molecules having prochirality has been developed by utilizing 4 ( R ) - methoxycarbonyl-1,3-thiazolidine-2-thione.In the model experiments of total synthesis of viginiamycin MZ, the derivatives of 1.3-oxoazolidine-2-thione and 1,3-thiazolidine-2-thione were utilized effectively.
Regulation of Metabolism: A Cross Talk Between Gut Microbiota and Its Human Host (2012)

The recent epidemic of obesity and diabetes and the diversity at the individual level could be explained by the intestinal microbiota-to-host relationship. More than four million gene products from the microbiome could interact with the immune system to induce a tissue metabolic infection, which is the molecular origin of the low-grade inflammation that characterizes the onset of obesity and diabetes.
Conserved Neuron Promoting Activity in and Vertebrate Laminin α1 (1996)

Drosophila S2 cells were transfected with constructs that code for two portions of the Drosophila laminin alpha chain. Construct recalphaL coded for domains III, I/II, and G of laminin alpha. Construct recalphaS coded for only the COOH-most 12% of the I/II domain and the G domain. The corresponding polypeptides were isolated and characterized from the culture media. The recalphaL chain partly formed disulfide-linked heterotrimers with the endogenously produced beta and gamma laminin chains. Like normal Drosophila laminin, a substrate coating of either recalphaL or recalphaS supported neuron differentiation and neurite extension of primary Drosophila embryo cell cultures. However, at the same low concentrations, only Drosophila laminin-1, but neither recalphaL nor recalphaS supported myogenesis in these cultures. Previously, an overlapping set of dodecapeptides that covered a region of the murine laminin alpha1 chain similar to recalphaS had been synthesized and tested for cell culture support properties (Nomizu, M., Kim, W. H., Yamamura, K., Utani, A., Otaka, A., Roller, P. P., Kleinman, H. K., and Yamada, Y. (1995) J. Biol. Chem. 270, 20583-20590). The Drosophila laminin alpha homologues of the six most active vertebrate dodecapeptides were now synthesized and tested as substrates for differentiation of primary Drosophila embryo cells. Peptides that contained either the Drosophila sequence SIKVGV or the murine homologue, SIKVAV, provided support for neurite extension.
An Observational Study of Bevacizumab-Induced Hypertension as a Clinical Biomarker of Antitumor Activity (2011)

Our preliminary results indicate that home-based measurement and grading according to the ESH criteria represents a reliable method to detect bevacizumab-induced hypertension. Whether hypertension is a biomarker of bevacizumab activity remains to be determined in a prospective study.
The Research of LED Arrays for Uniform Illumination (2012)

Nowadays, light emitting diodes (LEDs) are becoming a natural source choice for display illumination due to their small size, lower power consumption as well as lower heat generation. To be useful in practical display applications and to further improve the performance of LED-based illumination system, a secondary optical design for LED illumination is required to rearrange the direct output of LEDs so as to achieve a desired illumination. In this paper, a numerical modeling based on the direct datasheet fit is used to optimize and analyze the uniform illumination system designs, and close attention is paid to the LED source model. The uniformity of typical square and circular array distributions are analyzed for a commercial non-perfect Lambertian LED model.
Modeling Truth Existence in Truth Discovery (2015)

When integrating information from multiple sources, it is common to encounter conflicting answers to the same question. <i>Truth discovery</i> is to infer the most accurate and complete integrated answers from conflicting sources. In some cases, there exist questions for which the true answers are excluded from the candidate answers provided by all sources. Without any prior knowledge, these questions, named <i>no-truth questions</i>, are difficult to be distinguished from the questions that have true answers, named <i>has-truth questions</i>. In particular, these no-truth questions degrade the precision of the answer integration system. We address such a challenge by introducing <i>source quality</i>, which is made up of three fine-grained measures: silent rate, false spoken rate and true spoken rate. By incorporating these three measures, we propose a probabilistic graphical model, which simultaneously infers truth as well as source quality without any a priori training involving ground truth answers. Moreover, since inferring this graphical model requires parameter tuning of the prior of truth, we propose an initialization scheme based upon a quantity named <i>truth existence score</i>, which synthesizes two indicators, namely, <i>participation rate</i> and <i>consistency rate</i>. Compared with existing methods, our method can effectively filter out no-truth questions, which results in more accurate source quality estimation. Consequently, our method provides more accurate and complete answers to both has-truth and no-truth questions. Experiments on three real-world datasets illustrate the notable advantage of our method over existing state-of-the-art truth discovery methods.
Study of Energy-Saving Pulse Power for WEDM Based on Pulse Width Modulation (2009)

The energy efficiency of traditional pulse power for wire electrical discharge (WEDM) is less than 25% because of the use of current-limiting resistance. The new type of energy-saving resistor-less pulse power proposed in this paper employs the structure of a dual-arm power amplifier, the strategy of single-arm pulse width modulation (PWM) and the control mode of cutting off long-time short circuit. Heat generated by current-limiting resistance and useless power consumption caused by long-time short circuit is avoided, and therefore the energy efficiency is increased.
Consumption of<i>Buglossoides arvensis</i>seed oil is safe and increases tissue long-chain<i>n</i>-3 fatty acid content more than flax seed oil – results of a phase I randomised clinical trial (2016)

Enrichment of tissues with ≥20-carbon n-3 PUFA like EPA is associated with positive cardiovascular outcomes. Stearidonic acid (SDA; 18 : 4n-3) and α-linolenic acid (ALA; 18 : 3n-3) are plant-derived dietary n-3 PUFA; however, direct comparisons of their impact on tissue n-3 PUFA content are lacking. Ahiflower(®) oil extracted from Buglossoides arvensis seeds is the richest known non-genetically modified source of dietary SDA. To investigate the safety and efficacy of dietary Ahiflower oil, a parallel-group, randomised, double-blind, comparator-controlled phase I clinical trial was performed. Diets of healthy subjects (n 40) were supplemented for 28 d with 9·1 g/d of Ahiflower (46 % ALA, 20 % SDA) or flax seed oil (59 % ALA). Blood and urine chemistries, blood lipid profiles, hepatic and renal function tests and haematology were measured as safety parameters. The fatty acid composition of fasting plasma, erythrocytes, polymorphonuclear cells and mononuclear cells were measured at baseline and after 14 and 28 d of supplementation. No clinically significant changes in safety parameters were measured in either group. Tissue ALA and EPA content increased in both groups compared with baseline, but EPA accrual in plasma and in all cell types was greater in the Ahiflower group (time × treatment interactions, P ≤ 0·01). Plasma and mononuclear cell eicosatetraenoic acid (20 : 4n-3) and docosapentaenoic acid (22 : 5n-3) content also increased significantly in the Ahiflower group compared with the flax group. In conclusion, the consumption of Ahiflower oil is safe and is more effective for the enrichment of tissues with 20- and 22-carbon n-3 PUFA than flax seed oil.
Catching the boat with Strudel: experiences with a Web Site management system. (1998)

Managing Web sites is a tedious data-management task, because today&apos;s Web sites often are derived from multiple data sources and have complex structures. To simplify these tasks, Web-site builders need tools for managing Web sites&apos; content and structure. The Strudel system applies concepts from database management systems to the process of building Web sites. The key idea is separating the management of the site&apos;s data, the creation and management of the site&apos;s structure, and the graphical presentation of the site&apos;s pages. First, the site builder creates a uniform model of all the data available at the site. Second, the site builder uses this model to declaratively define the Web site&apos;s structure by applying a &quot;site-definition query&quot; to the underlying data. The result of evaluating this query is a &quot;site graph&quot;, which represents both the site&apos;s content and structure. Third, the site builder specifies the graphical presentation of pages in Strudel&apos;s HTML-template language. The data model...