gebhart/patrepeval huggingface dataset:
Consistent nonlinear elastic image registration (2002)

This paper describes a new bidirectional image registration algorithm that estimates a consistent set of nonlinear forward and reverse transformations between two N-dimeusional images. The registration problem is formulated in a N+1-dimensional space where the additional dimension is referred to as the temporal or time dimension. A periodic-in-time, nonlinear, N+1-dimensional transformation is estimated that deforms one image into the shape of the other and back again. The registration problem is solved numerically by discretizing the temporal dimension such that there is an incremental image and transformation at each time point. Nonlinear deformations from one image to the other are accommodated by concatenating the linear, small-deformation incremental transformations. An inverse consistency constraint is placed on the incremental transformations to enforce within a specified tolerance that the forward arid reverse transformations between the two images are inverses of each other. Results are presented for 2D image registration problems. These results demonstrate the feasibility of accommodating both linear and nonlinear deformations.
Breathheld autocalibrated phase‐contrast imaging (2010)

Flow measurements of images reconstructed with autocalibration techniques have comparable agreement with conventional PC-MRI and provide robust measurements in the presence of wraparound.
A recycling process for dezincing steel scrap (1992)

In response to the several-fold increase in consumption of galvanized steel in the last decade and the problems associated with refurnacing larger quantities of galvanized steel scrap, a process is being developed to separate and recover the steel and zinc from galvanized ferrous scrap. The zinc is dissolved from the scrap in hot caustic using anodic assistance and is electrowon as dendritic powder. The process is effective for zinc, lead, aluminum, and cadmium removal on loose and baled scrap and on all types of galvanized steel. The process has been pilot tested for batch treatment of 1,000 tons of mostly baled scrap. A pilot plant to continuously treat loose scrap is under construction. Use of degalvanized steel scrap decreases raw materials and environmental compliance costs to steel- and iron-makers, may enable integrated steel producers to recycle furnace dusts to the sinter plant, and may enable EAF production of flat products without use of DRI or pig iron. Recycling the components of galvanized steel scrap saves primary energy, decreases zinc imports, and adds value to the scrap.
Mixed block placement via fractional cut recursive bisection (2005)

Recursive bisection is a popular approach for large scale circuit placement problems, combining a high degree of scalability with good results. In this paper, we present a bisection-based approach for both standard cell and mixed block placement; in contrast to prior work, our horizontal cut lines are not restricted to row boundaries. This technique, which we refer to as a fractional cut, simplifies mixed block placement and also avoids a narrow region problem encountered in standard cell placement. Our implementation of these techniques in the placement tool Feng Shui 2.6 retains the speed and simplicity for which bisection is known, while making it competitive with leading methods on standard cell designs. On mixed block placement problems, we obtain substantial improvements over recently published work. Half perimeter wire lengths are reduced by 29% on average, compared to a flow based on Capo and Parquet; compared to mPG-ms, wire lengths are reduced by 26% on average.
Retrofitting of Continuous Glucose Monitoring Traces Allows More Accurate Assessment of Glucose Control in Outpatient Studies (2015)

The improved accuracy of retrofitted CGM with respect to the original CGM traces allows a more reliable assessment of glucose control in outpatient AP studies.
Development of a Chip-breaking Tool for Tapping (1st Report) (2004)

In tapping, chips jamming in the tap's flute or twining around the tap cause tool breakage very frequently. It has been an obstacle to automation of tapping. In order to resolve this problem, a chip-breaking tool has been developed, which forms grooves axially on the inner wall of hole before tapping. In this paper described are design of the tool and its effectiveness. The tool was composed of a cylindrical body and three V-groove cutting edges. The diameter of body was equal to that of tap drills. The major diameter of V-groove cutting edges was slightly larger than that of taps. Each V-groove cutting edge had a chip pocket designed after observing the chip formation in similar V-groove cutting. To investigate the effectiveness of the tool, tapping experiments for M3 and M6 threads were performed with and without using the tool. The work material was structural steel SS400 and the taps used were the conventional spiral fluted taps made of high speed steel. By using a machining center the tapping operations were automatically repeated till when the tap was broken without any human assistance for removing the chips jamming in the tap's flute or twining around the tap. To shorten the experimental time, the cutting velocity for tapping was set at 30m/min which was much higher than conventional, and besides, the thread was long as two and a half times of diameter. It has been ascertained by experiments that by using the newly developed tool, the tool life of tap lasts much longer and the tapping torque becomes smaller and stable, and moreover, the surface roughness becomes smoother.
Modelling Tumor Treating Fields for the treatment of lung-based tumors (2015)

Tumor Treating Fields (TTFields), low-intensity electric fields in the frequency range of 100-500 kHz, exhibit antimitotic activity in cancer cells. TTFields were approved by the U. S. Food and Drug Administration for the treatment of recurrent glioblastoma in 2011. Preclinical evidence and pilot studies suggest that TTFields could be effective for treating certain types of lung cancer, and that treatment efficacy depends on the electric field intensity. To optimize TTFields delivery to the lungs, it is important to understand how TTFields distribute within the chest. Here we present simulations showing how TTFields are distributed in the thorax and torso, and demonstrate how the electric field distribution within the body can be controlled by personalizing the layout of the arrays used to deliver the field.
Synthesis and in vitro Inhibitory Effect of L-Glycosyl-Branched Curdlan Sulfates on AIDS Virus Infection (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis and in vitro Inhibitory Effect of L-Glycosyl-Branched Curdlan Sulfates on AIDS Virus InfectionTakashi Yoshida, Yuichi Yasuda, Toshiyuki Uryu, Hideki Nakashima, Naoki Yamamoto, Toru Mimura, and Yutaro KanekoCite this: Macromolecules 1994, 27, 22, 6272–6276Publication Date (Print):October 1, 1994Publication History Published online1 May 2002Published inissue 1 October 1994https://pubs.acs.org/doi/10.1021/ma00100a007https://doi.org/10.1021/ma00100a007research-articleACS PublicationsRequest reuse permissionsArticle Views219Altmetric-Citations20LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
FlashQueryFile: flash-optimized layout and algorithms for interactive ad hoc SQL on big data (2014)

High performance storage layer is vital for allowing interactive ad hoc SQL analytics (OLAP style) over Big Data. The paper makes a case for leveraging flash in the Big Data stack to speed up queries. State-of-the-art Big Data layouts and algorithms are optimized for hard disks (i.e., sequential access is emphasized over random access) and result in suboptimal performance on flash given its drastically different performance characteristics. While existing columnar and row-columnar layouts are able to reduce disk IO compared to row-based layouts, they still end up reading significant columnar data irrelevant to the query as they only employ coarse-grained, intra-columnar data skipping which doesn't work across all queries. FlashQueryFile's specialized columnar data layouts, selection, and projection algorithms fully exploit fast random accesses and high internal I/O parallelism of flash to allow fast and I/O-efficient query processing and fine-grained, intra-columnar data skipping to minimize data read per query. FlashQueryFile results in 11X-100X TPC-H query speedup and 38%-99.08% reduction in data read compared to flash-based HDD-optimized row-columnar data layout and its associated algorithms.
High-performance, reliable, 730 nm-emitting Al-free active region diode lasers (2002)

Compressively-strained InGaAsP QW active (/spl lambda/=732 nm) diode lasers achieve 2.4 W CW front-facet power from 100 /spl mu/m-wide apertures, with reliable operation at 0.5 W CW. Record-high characteristic temperatures for the threshold current and the differential quantum efficiency, T/sub 0/=115 K and T/sub 1/=285 K are obtained by growing on misoriented substrates.
Reflectarrays for satellite telecommunication antennas (2007)

The objective of this paper is to highlight some of the issues related to the development of Reflectarrays for satellite telecommunication antennas. (6 pages)
Lock Detector Integrated in a High Order Frequency Multiplier Operating at 60-GHz-Band in 45nm CMOS SOI Technology (2020)

This paper presents a lock detector integrated in a 60GHz band frequency multiplier with high multiplication factor. The proposed circuit detects the locking state of an injection locked oscillator. It relies on power integration besides the ILO targeted frequency. The proposed lock detector and the associated frequency multiplier presents a consumption of 61 mW and 5.2 mW respectively. The area occupied by the lock detector is less than 3% of the overall chip area. The locking detector is the cornerstone of injected oscillator calibration, and enables high-N frequency multiplication-based frequency synthesis.
Pilot-based crosstalk channel estimation for vector-enabled VDSL systems (2010)

Recently, the International Telecommunication Union has consented the ITU-T G.993.5 recommendation on vectoring in VDSL2 technology, which specifies the required functionality for interoperability between chipsets of different vendors to achieve vectoring. This paper will briefly review the principles of vectoring and the underlying precoding and channel estimation techniques. This framework is then used to introduce mechanisms for crosstalk channel estimation that exploit channel smoothness with the aid of frequency-dependent pilot sequences, as well as mechanisms that allow fast and simultaneous initialization by targeted assignment of pilot sequences. A pilot-based technique is described that exploits the robustness of the synchronization symbols to estimate crosstalk emanating from ¿legacy¿ VDSL2 lines within a vectoring group. This allows cancellation of crosstalk from legacy lines without replacement of the installed VDSL2 customer premises equipment. Some of these techniques are compatible with the current version of ITU-T G.993.5 recommendation, while others require changes that are under consideration for possible inclusion in future amendments.
K-edge subtraction angiography with synchrotron x-rays: Final technical report, (February 1, 1984 to January 31, 1987) (1987)

The aim was the development of an angiographic method and appropriate equipment for imaging with x-rays the coronary arteries in a non-invasive manner. Successive steps involved studies with phantoms, live animals and finally with human subjects. Clinical evaluation of human coronary arteries remains a goal of this and a continuing project, and steps along the way to such an achievement are in process. Transvenous injection of a dye using the method of iodine dichromography near 33.2 keV, the K-edge of iodine, forms the basis of the method. 11 refs.
Post-exposure Treatment of Cats with Mouse-Cat Chimeric Antibodies against Feline Herpesvirus Type 1 and Feline Calicivirus. (2002)

In order to confirm the in vivo effectiveness of anti- feline herpesvirus type 1 (FHV-1) mouse-cat chimeric antibody (FJH2), and anti-feline calicivirus (FCV) mouse-cat chimeric antibody (F1D7), cats that had been experimentally infected with FHV-1 or FCV were administered intravenously with the chimeric antibodies, and observed for clinical manifestations. The symptoms due to FHV-1 or FCV infection in the cats administered FJH2 or F1D7 were obviously decreased when compared with those of the non-administered control cats. From these results, it was confirmed that both FJH2 and F1D7 were effective at reducing the appearance of symptoms due to FHV-1 and FCV infection, respectively.
Inverse Fourier transform technique to determine second-order optical nonlinearity spatial profiles (2003)

A technique is described to measure the second-order nonlinearity spatial profile of nonlinear films. It consists of placing two identical samples back-to-back to create a symmetric nonlinearity profile and measuring the Maker fringes of this sample. Because the profile is symmetric, both its shape and location inside the film can be determined uniquely from the Maker fringe data. Applied to a sample of thermally poled silica, this method reveals a nonlinearity profile that is both deeper (∼25 μm) and stronger (peak d33=0.8 pm/V) than previously believed, with spatial features that could not be resolved with previous techniques. This powerful principle is applicable to many other physical problems in which the amplitude, but not the phase, of the Fourier transform can be measured.
Designing ice recrystallization inhibitors: from antifreeze (glyco)proteins to small molecules (2014)

Ice recrystallization occurs during cryopreservation and is correlated with reduced cell viability after thawing.
CEDARS: Combined exploratory data analysis recommender system (2015)

We present a framework for recommender systems (RS) to support exploratory data analysis (EDA) in analytical decision making. EDA helps the domain expert, often not a statistical expert, discover interesting relationships between variables and thus be motivated to explain the data. By capturing the behavior of expert analysts in EDA, RS could advise domain experts of “standard” analytical operations and suggest operations novel to the domain but consistent in analytical goals with requested operations. We enhance our framework with rules that encapsulate standard analytical practice and by incorporating user preferences. We present a scalable framework architecture, which we implemented in a prototype system, and discuss two use cases where the prototype was exercised, analyzing data from image analysis and analyzing eye tracking data.
Automated Alignment and Nomenclature for Consistent Treatment of Polymorphisms in the Human Mitochondrial DNA Control Region (2010)

Naming mtDNA sequences by listing only those sites that differ from a reference sequence is the standard practice for describing the observed variations. Consistency in nomenclature is desirable so that all sequences in a database that are concordant with an evidentiary sequence will be found for estimating the rarity of that profile. The operational alignment and nomenclature rules, i.e., "Wilson Rules," suggested for this purpose do not always guarantee a single consistent sequence description for all observed polymorphisms. In this work, the operational alignment/nomenclature rules were reconfigured to better reflect traditional user preferences. The rules for selecting alignments are described. In addition, to avoid human error and to more efficiently name mtDNA sequence variants, a computer-facilitated method of aligning mtDNA sample sequences with a reference sequence was developed. There were 33 differences between these hierarchical rules and the data in SWGDAM, which translates into a 99.92% consistency between the new rules and the manual historical nomenclature approach. The data support the reliability of the current SWGDAM database. As the few discrepancies were changed in favor of the new hierarchical rules, the quality of the SWGDAM database is further improved.
Compact direct space-to-time pulse shaping with a phase-only spatial light modulator (2011)

A very compact and innovative pulse shaper is proposed and demonstrated. The standard architecture for pulse shaping that is composed of diffraction gratings associated with an amplitude-phase spatial light modulator (SLM) is replaced by a single phase-only SLM. It acts as a pulse stretcher and as an amplitude and phase modulator at the same time. Preliminary experiments demonstrate the accurate control of amplitude and phase of shaped pulses.
Mid-infrared lasing characteristics of praseodymium doped lanthanum trichloride (1994)

In order to extend the range of solid state laser sources further into the mid-IR, we have explored the stimulated emission properties of praseodymium in low phonon energy host crystals. As a result, we have obtained efficient pulsed operation at the longest wavelength reported to date for any rare earth laser, 5.25 μm.1 In addition, a new high gain, three level Pr+3 laser line at 1.64 μm has also been characterized. See Fig. 1.
Resonantly enhanced vacuum ultraviolet generation and multiphoton ionization in carbon monoxide gas (1982)

Competition between three-photon resonantly enhanced vacuum ultraviolet third-harmonic generation and six-photon multiphoton ionization using the A state in gaseous carbon monoxide is observed. Excitation spectra of the third-harmonic emission exhibit increasing blue shifts and broadening with increasing pressure due to the phase matching requirements. Estimates for the efficiency and tunability show that third-harmonic generation in carbon monoxide molecules is a promising source for coherent vacuum ultraviolet light.
IL-12 as an adjuvant for cell-mediated immunity (1997)

Recent studies have shown that IL-12 initiates the development of cell-mediated immunity following infection with certain infectious agents. This attribute of IL-12 makes it a potentially effective adjuvant for vaccines. This review summarizes our findings in the Leishmania system, outlining the role of endogenous IL-12 in resistance to L. major and the use of exogenous IL-12 in a vaccine against L. major, and also describes other examples in which IL-12 has been shown to be effective as an adjuvant at inducing protective immunity. The potential use of IL-12 as an adjuvant in therapeutic vaccines is also discussed.
Digital holographic microscopy for remote life detection (2018)

The presence of oceans on the outer solar system moons Europa and Enceladus poses the question of whether microbial life might be present on those bodies. One approach to answering that question could be a very compact, lightweight and robust microscope that is capable of rapidly imaging the contents of a 3-dimensional sample volume. To this end, we have been developing deployable digital holographic microscopes, which can also be used in the short term for terrestrial field work. A very stable “common-mode” microscope, in which two adjacent beams share several optics, has shown very good imaging performance, and has been deployed successfully to several field sites, including Greenland and Alaska. A more compact approach is our version of the lensless digital holographic microscope, which uses gradient index rod lenses to produce a pair of high numerical-aperture input beams. Sub-micron resolution has been obtained with both systems, and further performance improvements are possible.
Power loss design platform for high output power density converters (2007)

A novel circuit parameter design concept called "Power Loss Design Platform" has been proposed to realize high output power density (OPD) converters. The platform concept enables the exact power loss design, taking the effect of correlations among converter parameters into consideration under real circuit condition. An experimental apparatus has been fabricated based on the platform concept. Details of the power loss design methods for semiconductor power devices and passive filters are presented. The validity of proposed methods is confirmed in the chopper circuit and the inverter circuit. The platform concept for the circuit parameter design enables the optimal circuit parameter extraction under real circuit conditions.
PS2 - 153 Dianhydrogalactitol (VAL-083) Treatment Causes Irreparable DNA Double-Strand Breaks, S/G2 Phase Cell-Cycle Arrest and Cell Death in Cancer Cells (2016)

Dianhydrogalactitol (VAL-083) is a unique bi-functional alkylating agent causing N7-guanine-methylation and inter-strand DNA crosslinks. VAL-083 readily crosses the blood-brain barrier, accumulates in brain tumor tissue and has shown activity in prior NCI-sponsored clinical trials against various cancers, including glioblastoma (GBM) and medulloblastoma. VAL-083 is also active against GBM cancer stem cells and acts as a radiosensitizer independent of O6-methylguanine-DNA methyltransferase activity (in contrast to e.g. temozolomide and BCNU). Here we report new insights into VAL-083 mechanism of action by showing that VAL-083 induces irreversible cell-cycle arrest and cell death caused by replication-dependent DNA damage. In lung (H2122, H1792, H23, A549) and prostate (PC3, LNCaP) cancer cell lines VAL-083 treatment caused irreversible S/G2 cell-cycle arrest and cell death (IC50 range 3.06-25.7 µM). VAL-083 pulse-treatment led to persistent phosphorylation of DNA double-strand breaks (DSB) sensors ATM, single-strand DNA-binding Replication Protein A (RPA32), and histone variant H2A.X, suggesting persistent DNA lesions. After 10 months in culture with increasing VAL-083 concentrations, H1792 and LNCaP cells survive at concentrations up to 9.4 µM and 7.4 µM, respectively, suggesting that efficient resistance mechanisms are not easily acquired by the cancer cells. Taken together with previous results showing that VAL-083 circumvents cisplatin-resistance and is less dependent on p53 activity than cisplatin, these results suggest a molecular mechanism for VAL-083 that differs from both TMZ, BCNU and cisplatin. They further suggest that irreparable DNA damage induced by VAL-083 is impervious to common strategies employed by cancer cells to escape effects of alkylating drugs used in GBM treatment.
Interior Lining or Covering Element for Motor Vehicles (2011)

The invention relates to a lining element, in particular an interior lining and/or covering element, for motor vehicles, having a decorative layer and a support layer structure with at least one support layer, in which the air permeability and/or density and/or the mass per unit area of the support layer structure are preset for controlling the acoustic properties, and to a method for producing a lining element, in particular an interior lining element or covering element for motor vehicles, having a decorative layer and a support layer structure of at least one support layer with controlled acoustic properties. In particular, the acoustic properties of the lining element are controlled by matching the thickness, and/or the mass per unit area, and/or the air permeability of the lining element in zones, or over the entire surface, to sound emissions which are to be absorbed.