gebhart/patrepeval huggingface dataset:
Extending Correlation Filter-Based Visual Tracking by Tree-Structured Ensemble and Spatial Windowing (2017)

Correlation filters have been successfully used in visual tracking due to their modeling power and computational efficiency. However, the state-of-the-art correlation filter-based (CFB) tracking algorithms tend to quickly discard the previous poses of the target, since they consider only a single filter in their models. On the contrary, our approach is to register multiple CFB trackers for previous poses and exploit the registered knowledge when an appearance change occurs. To this end, we propose a novel tracking algorithm [of complexity O(D) ] based on a large ensemble of CFB trackers. The ensemble [of size O(2<sup>D</sup>) ] is organized over a binary tree (depth D ), and learns the target appearance subspaces such that each constituent tracker becomes an expert of a certain appearance. During tracking, the proposed algorithm combines only the appearance-aware relevant experts to produce boosted tracking decisions. Additionally, we propose a versatile spatial windowing technique to enhance the individual expert trackers. For this purpose, spatial windows are learned for target objects as well as the correlation filters and then the windowed regions are processed for more robust correlations. In our extensive experiments on benchmark datasets, we achieve a substantial performance increase by using the proposed tracking algorithm together with the spatial windowing.
<i>SPG15</i> is the second most common cause of hereditary spastic paraplegia with thin corpus callosum (2009)

The mutations are truncating, private, and distributed along the entire coding sequence of ZFYVE26, which complicates the analysis of this gene in clinical practice. In our series of patients with hereditary spastic paraplegia-thin corpus callosum, the largest analyzed so far, SPG15 was the second most frequent form (11.5%) after SPG11. Both forms share similar clinical and imaging presentations with very few distinctions, which are, however, insufficient to infer the molecular diagnosis when faced with a single patient.
High performance ripple feedback for the buck unity-power-factor rectifier (1995)

The buck unity-power-factor rectifier has harmonic-free input current with complete load regulation down to zero output voltage. A new "nonlinear ripple feedback" is proposed which exactly cancels the spoiling effect of DC-side current ripple on the low-distortion AC line current waveforms, even for large amounts of ripple. This cancellation is independent of operating point and readily implemented with analog hardware, thereby permitting economies in the design of the DC filter while maintaining harmonic-free operation. Both large-signal and incremental analyses of the rectifier are given. Confirming experimental results from a 1 kW 48 V isolated battery charger operating with current-ripple levels ranging from 50% to discontinuous-conduction-mode operation are given.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
14.2 A physically unclonable function with BER &#x003C;10<sup>&#x2212;8</sup> for robust chip authentication using oscillator collapse in 40nm CMOS (2015)

Security is a key concern in today's mobile devices and a number of hardware implementations of security primitives have been proposed, including true random number generators, differential power attack avoidance, and chip-ID generators [1-4]. Recently, physically unclonable functions (PUFs) were proposed as a secure method for chip authentication in unsecure environments [5-7]. A PUF is a function that maps an input code ("challenge') to an output code (“response”) in a manner that is unique for every chip. PUFs are increasingly used for IC authentication to offer protection against identity theft, cloning, and counterfeit components [2-4].
Molecular biology of calcific aortic valve disease: towards new pharmacological therapies (2014)

Calcific aortic valve disease (CAVD) is a chronic process leading to fibrosis and mineralization of the aortic valve. Investigations in the last several years have emphasized that key underlying molecular processes are involved in the pathogenesis of CAVD. In this regard, the processing of lipids and their retention has been underlined as an important mechanism that triggers inflammation. In turn, inflammation promotes/enhances the mineralization of valve interstitial cells, the main cellular component of the aortic valve. On the other hand, transformation of valve interstitial cells into myofibroblasts and osteoblast-like cells is determined by several signaling pathways having reciprocal cross-talks. In addition, the mineralization of the aortic valve has been shown to rely on ectonucleotidase and purinergic signaling. In this review, the authors have highlighted key molecular underpinnings of CAVD that may have significant relevance for the development of novel pharmaceutical therapies.
<title>Optimal parallel error diffusion dithering</title> (1998)

Error diffusion dithering is a technique that is used to represent a grayscale image on a printer, a computer monitor or other bi-level displays. For a number of year it was believed that error diffusion algorithms can not be parallelized. On this paper we present a simple error- diffusion parallel algorithm that can be easily implemented on parallel computers that contain linear arrays of processing elements. It can also be implemented easily on specialized hardware. One of the advantages of our algorithm is its low implementation cost, its scalability, and its ability to benefit from standard fault-tolerance techniques.
Stretchable fiber-Bragg-grating-based sensor (2018)

A fiber-Bragg-grating-(FBG)-based sensor is a very popular fiber optic sensor due to its simplicity, mature fabrication technology, and sensitivity to a number of physical stimuli. However, due to the stiff nature of optical fiber, it is impossible to heavily stretch a FBG sensor. A stretchable sensor is highly desired in soft robotics, human motion detection, and biomedical applications, which could involve motions like tension, bending, and twisting. In this Letter, we demonstrate a stretchable FBG-based fiber optic sensor by embedding a FBG-written optic fiber sinusoidally in a soft silicone film at an off-center position. This unique structure enables 30% of elongation in length that facilitates tension, bending, and twisting measurement.
Fungal Indole Alkaloid Biogenesis Through Evolution of a Bifunctional Reductase/Diels-Alderase (2018)

Prenylated indole alkaloids isolated from various fungi possess great structural diversity and pharmaceutical utility. Among them are the calmodulin inhibitory malbrancheamides and paraherquamides, used as anthelmintics in animal health. Herein, we report complete elucidation of the malbrancheamide biosynthetic pathway accomplished through complementary approaches. These include a biomimetic total synthesis to access the natural alkaloid and biosynthetic intermediates in racemic form, and in vitro enzymatic reconstitution that provides access to the natural antipode (+)-malbrancheamide. Reductive cleavage of a L-Pro-L-Trp dipeptide from the MalG nonribosomal peptide synthetase (NRPS) followed by reverse prenylation and a cascade of post-NRPS reactions culminates in an intramolecular [4+2] hetero-Diels-Alder (IMDA) cyclization to furnish the bicyclo[2.2.2]diazaoctane scaffold. Enzymatic assembly of optically pure (+)-premalbrancheamide involves an unexpected zwitterionic intermediate where MalC catalyzes enantioselective cycloaddition as a bifunctional NADPH-dependent reductase/Diels-Alderase. Crystal structures of substrate and product complexes together with site-directed mutagenesis and molecular dynamics simulations demonstrated how MalC and PhqE, its homolog from the paraherquamide pathway, catalyze diastereo- and enantioselective cyclization in the construction of this important class of secondary metabolites.
BTS: A new ferroelectric for multifunctional sensors (1990)

Abstract A new series of multifunctional sensitive ferroelectric ceramics, BaTiO3-BaSnO3 have been studied. They can rapidly detect temperature, humidity and gas presence by means of a single sensor. This is the first time that such multifunctional sensors have been reported. The crystalline phase, porous structure, pore system, semiconduction and temperature-humidity-gas sensing characteristics of BTS porous ferroelectric ceramics were investigated.
Empirically Detecting False Test Alarms Using Association Rules (2015)

Applying code changes to software systems and testing these code changes can be a complex task that involves many different types of software testing strategies, e.g. system and integration tests. However, not all test failures reported during code integration are hinting towards code defects. Testing large systems such as the Microsoft Windows operating system requires complex test infrastructures, which may lead to test failures caused by faulty tests and test infrastructure issues. Such false test alarms are particular annoying as they raise engineer attention and require manual inspection without providing any benefit. The goal of this work is to use empirical data to minimize the number of false test alarms reported during system and integration testing. To achieve this goal, we use association rule learning to identify patterns among failing test steps that are typically for false test alarms and can be used to automatically classify them. A successful classification of false test alarms is particularly valuable for product teams as manual test failure inspection is an expensive and time-consuming process that not only costs engineering time and money but also slows down product development. We evaluating our approach on system and integration tests executed during Windows 8.1 and Microsoft Dynamics AX development. Performing more than 10,000 classifications for each product, our model shows a mean precision between 0.85 and 0.90 predicting between 34% and 48% of all false test alarms.
Effect of Pyrrole Implants Synthesized by Different Methods on Spinal Cord Injuries of Rats (2015)

Polypyrrole (PPy) and polypyrrole/polyethylene glycol (PPy/PEG) implants synthesized by chemical, electro-chemical, and plasma polymerization methods were implanted into the injured spinal cord of rats to determine their effect on motor function recovery. Before implantation, the materials were characterized by infrared (IR) spectroscopy. An experimental model of traumatic spinal cord injury (TSCI) by complete transection at thoracic level 9, in rats was used. The polymer implants were inserted immediately after transection. Motor function recovery was evaluated once a week during 5 weeks using the Basso, Beattie and Bresnahan (BBB) motor scale. Histological evaluation was done at the end of the recovery evaluation period using hematoxylin/eosin stain. Results showed that animals implanted with polymers synthesized by plasma had a better integration into the nerve tissue, less inflammatory response and a better functional recovery than animals implanted with polymers synthesized by chemical or electrochemical methods.
Long-term presence of white spot syndrome virus (WSSV) in a cultivated shrimp population without disease outbreaks (1999)

PCR and in situ hybridization analysis were used for detection of white spot syndrome virus (WSSV) in an infected, cultured shrimp population over a long period in the absence of disease outbreaks. The shrimp were derived from a single WSSV-carrier brooder and cultured first in a tank and then in outdoor ponds. Prior to harvest at 13 mo, no l-step PCR-positive specimens were found, even though most tested specimens were found to be 2-step PCR-positive. At 7 mo, 2-step PCR-positive tissues were found in 5 sampled shrimp. Heart, gill, integument, muscle and stomach tissues best supported viral replication At 13 mo several shrimp died, and l-step PCR-positive individuals were found for the first time Although superficially healthy, 10% of the surviving adults had tiny white spots on their carapace, and In sjtu hybridization analysis revealed WSSV-positive cells in 40% of the specimens examined. As before, most were found in the stomach, integument and gills, and only very few in the lymphoid organ and other organs. These observations contrasted to those for experimentally infected shrimp with gross signs of terminal WSSV infection, where strong positive signals were also observed in the lymphoid organ and in other organs of ectodermal or mesodermal origin. Our results showed clearly that whatever the source, WSSV was carried in the shrimp population at a low intensity (i.e. nested PCR was required for detection) for a very long time in the absence of massive mortality. We hypothesize that disease outbreaks do not occur if shrimp defense mechanisms manage to contain lowintensity viral infections under low-stress culture conditions. Conversely, outbreaks may occur under stressful conditions.
Magnetic shielding of a laboratory Hall thruster. II. Experiments (2014)

The physics of magnetic shielding in Hall thrusters were validated through laboratory experiments demonstrating essentially erosionless, high-performance operation. The magnetic field near the walls of a laboratory Hall thruster was modified to effectively eliminate wall erosion while maintaining the magnetic field topology away from the walls necessary to retain efficient operation. Plasma measurements at the walls validate our understanding of magnetic shielding as derived from the theory. The plasma potential was maintained very near the anode potential, the electron temperature was reduced by a factor of two to three, and the ion current density was reduced by at least a factor of two. Measurements of the carbon backsputter rate, wall geometry, and direct measurement of plasma properties at the wall indicate that the wall erosion rate was reduced by a factor of 1000 relative to the unshielded thruster. These changes effectively eliminate wall erosion as a life limitation in Hall thrusters, enabling a new class of deep-space missions that could not previously be attempted.
A bifunctional peptide, “peptope”, for pre-targeting antibody 7D8 to systemic amyloid deposits (2017)

"A bifunctional peptide, "peptope", for pre-targeting antibody 7D8 to systemic amyloid deposits." Amyloid, 24(sup1), pp. 22–23
RAPIDLY TUNABLE ACOUSTIC GRADIENT INDEX LENSES FOR PULSED IMAGING AND LASER PROCESSING (2009)

A MHz-rate device employing acoustic waves within a fluid is used to reshape and focus an incident laser beam. Rapidly changeable focal lengths and patterns can be formed for pulsed imaging and processing applications.
LDPC Codes from Latin Squares Free of Small Trapping Sets (2010)

This paper is concerned with the construction of low-density parity-check (LDPC) codes with low error floors. Two main contributions are made. First, a new class of structured LDPC codes is introduced. The parity check matrices of these codes are arrays of permutation matrices which are obtained from Latin squares and form a finite field under some matrix operations. Second, a method to construct LDPC codes with low error floors on the binary symmetric channel (BSC) is presented. Codes are constructed so that their Tanner graphs are free of certain small trapping sets. These trapping sets are selected from the Trapping Set Ontology for the Gallager A/B decoder. They are selected based on their relative harmfulness for a given decoding algorithm. We evaluate the relative harmfulness of different trapping sets for the sum product algorithm (SPA) by using the topological relations among them and by analyzing the decoding failures on one trapping set in the presence or absence of other trapping sets.
Precise Determination of the Optimal Coil for Wireless Power Transfer Systems Through Postprocessing in the Smooth Boundary Representation (2017)

Recently, the layout optimization of the secondary coils for wireless power transfer systems has been developed using the fixed grid (FG) representation. Although this method can effectively and efficiently determine the optimized coil design under the given conditions, a distinct discrepancy exists between the evaluated coil mass (i.e., simulation data) and the physical coil mass (i.e., experiment data). In this paper, the FG-based coil layout optimization is revisited based on the smooth boundary (SB) representation in order to resolve the inherent drawbacks of the FG representation. Induced voltage, electromagnetic field strength, and coil mass, which have been previously derived in the FG representation, are reformulated in terms of design variables (i.e., a reference turn and relative turns in this paper) in the SB representation. Through the layout optimization, the optimized layouts of the secondary coil are determined in order to minimize the coil mass while satisfying the constraints for induced voltage and magnetic field strength; then, they are postprocessed in order to obtain a smooth, elaborate boundary. The experimental validation demonstrates that the proposed SB-based approach outperforms the previous FG-based method in terms of coil mass and boundary representation.
Low-voltage differentially-signaled modulators (2011)

For exascale computing applications, viable optical solutions will need to operate using low voltage signaling and with low power consumption. In this work, the first differentially signaled silicon resonator is demonstrated which can provide a 5dB extinction ratio using 3fJ/bit and 500mV signal amplitude at 10Gbps. Modulation with asymmetric voltage amplitudes as low as 150mV with 3dB extinction are demonstrated at 10Gbps as well. Differentially signaled resonators simplify and expand the design space for modulator implementation and require no special drivers.
Induction of Macrophage Tumoricidal Activity by Granulocyte-Macrophage Colony-Stimulating Factor (1986)

Monocytes are a subpopulation of peripheral blood leukocytes, which when appropriately activated by the regulatory hormones of the immune system, are capable of becoming macrophages--potent effector cells for immune response to tumors and parasites. A complementary DNA for the T lymphocyte-derived lymphokine, granulocyte-macrophage colony-stimulating factor (GM-CSF), has been cloned, and recombinant GM-CSF protein has been expressed in yeast and purified to homogeneity. This purified human recombinant GM-CSF stimulated peripheral blood monocytes in vitro to become cytotoxic for the malignant melanoma cell line A375. Another T cell-derived lymphokine, gamma-interferon (IFN-gamma), also stimulated peripheral blood monocytes to become tumoricidal against this malignant cell line. When IFN-gamma activates monocytes to become tumoricidal, additional stimulation by exogenously added lipopolysaccharide is required. No such exogenous signals were required for the activation of monocytes by GM-CSF.
ChemInform Abstract: SYNTHESIS AND BIOLOGICAL ACTIVITY OF A NEW CLASS OF CYTOTOXIC AGENTS: N‐(3‐OXOPROP‐1‐ENYL)‐SUBSTITUTED PYRIMIDINES AND PURINES (1985)

Abstract Dargestellt werden die Verbindungen (III), (IV) und (VI) sowie PyrimidyInucleosid‐Derivate, die auf cxtotoxische Wirkung geprüft werden.
Reduction of surface recombination current with an oxygen-doped Al0.5Ga0.5As surface layer on <i>n</i>-type GaAs (1979)

The surface recombination current of GaAs p–n junctions has been reduced by the use of a high resistivity O-doped Al0.5Ga0.5As layer on the n-type layer. A top layer of insulating silicon nitride provides protection from the environment so that this combination meets the requirements of a GaAs surface passivation. Reduction of the surface recombination current results in domination of the kT bulk diffusion current for current densities in excess of 5×10−3 A/cm2. Analysis of the forward I–V characteristics permits assignment of several parameters for these planar p–n junctions. The intrinsic surface recombination velocity–surface diffusion length product soLs was reduced from 3.7 to 0.3 cm2/s by the O–Al0.5Ga0.5As layer. The hole diffusion length Lp was found to be 3.2 μm and the internal quantum efficiency ηq=28%. The product of the space–charge region recombination center concentration NB, the capture-cross section ?, and the thermal velocity ? was NB??=4×107s−1.
Erosive Rheumatoid Arthritis Is Associated with Antibodies That Activate PAD4 by Increasing Calcium Sensitivity (2013)

Peptidylarginine deiminases (PADs) play a critical role in generating autoantigens in rheumatoid arthritis (RA), but the mechanisms underlying their dysregulation in this disease remain unknown. Although PADs require supraphysiologic concentrations of calcium for activity in vitro, the enzymes are active in vivo (for example, in RA synovial fluid) where calcium concentrations are much lower. We have discovered a subset of anti-PAD4 autoantibodies (identified by their cross-reactivity with PAD3) that markedly increase the catalytic efficiency of PAD4 by decreasing the enzyme's requirement for calcium into the physiologic range. Patients with these PAD3/PAD4 cross-reactive autoantibodies had higher baseline radiographic damage scores and a higher likelihood of radiographic progression compared to individuals negative for these antibodies. The ability of autoantibodies to activate an enzyme that itself generates citrullinated autoantigens identifies an important feed-forward loop, which may drive the erosive outcome observed in RA patients with these autoantibodies. PAD3 autoantibodies may therefore identify RA patients who would benefit from early aggressive treatment or addition of PAD inhibitor therapy.
A New Dual Current-Mode Controller Improves Power Regulation in Electrosurgical Generators (2011)

A new dual current-mode controller produces a fast, accurate constant-power high-frequency ac output, with maximum current and voltage limits for an electrosurgical generator. The regulation of ac output power is achieved with near-deadbeat control, without measurement or feedback of the output voltage or current. Compared to existing technology, the prototype generator reduces unintended tissue damage by significantly improving regulation of output power, while reducing complexity and parts count.
Efficient conversion of lignin into a water-soluble polymer by a chelator-mediated Fenton reaction: optimization of H<sub>2</sub>O<sub>2</sub>use and performance as a dispersant (2018)

Transforming lignin into a water-soluble polymer.
TIE breaking (2005)

The separation of intradomain and interdomain routing has been a key feature of the Internet's routing architecture from the early days of the ARPAnet. However, the appropriate "division of labor" between the two protocols becomes unclear when an Autonomous System (AS) has interdomain routes to a destination prefix through multiple border routers---a situation that is extremely common today because neighboring domains often connect in several locations. We believe that the current mechanism of early-exit or hot-potato routing---where each router in an AS directs traffic to the "closest" border router based on the intradomain path costs---is convoluted, restrictive, and sometimes quite disruptive. In this paper, we propose a flexible mechanism for routers to select the egress point for each destination prefix, allowing network administrators to satisfy diverse goals, such as traffic engineering and robustness to equipment failures. We present one example optimization problem that uses integer-programming techniques to tune our mechanism to improve network robustness. Experiments with topology and routing data from two backbone networks demonstrate that our solution is both simple (for the routers) and expressive (for the network administrators).