gebhart/patrepeval huggingface dataset:
Olfactory relationships of the telencephlaon and diencephalon in the rabbit. 1. An autoradiographic study of the efferent connections of the main and accessory olfactory bulbs (1975)

The efferent connections of the main and accessory olfactory bulbs in the female albino rabbit have been studied using the autoradiographic method for tracing axonal pathways. Following unilateral injections of 3H-proline or 3H-leucine into the main olfactory bulb, radioactively labeled material transported intraaxonally by axoplasmic flow in an anterograde direction from soma to axon terminal is present ipsilaterally in the superficial half of the plexiform layer (IA) of: the entire circumference of the olfactory peduncle, the tenia tecta, the full mediolateral extent of the olfactory tubercle, the entire length of the prepyriform cortex, a transition area between the prepyriform cortex and the horizontal limb of the nucleus of the diagonal band, the nucleus of the lateral olfactory tract, the anterior cortical and posterolateral cortical amygdaloid nuclei (periamygdaloid areas 1, rostral half of 2, 5 of Rose, '31), and the ventrolateral entorhinal cortex (entorhinal areas 1, 2, 4, 5, 7 of Rose, '31). No subcortical or contralateral projection of main bulb efferents was found. After a unilateral injection of 3H-leucine into the accessory olfactory bulb, transported material could be followed caudally along the dorsal surface of the ipsilateral lateral olfactory tract. This heavily labeled projection is distinct from the unlabeled lateral olfactory tract and has been termed the accessory olfactory tract. Beginning at the level of the caudal third of the olfactory tubercle and extending caudally to the nucleus of the lateral olfactory tract is a group of small neurons intimately associated with the accessory olfactory tract. This cell group is referred to as the bed nucleus of the accessory olfactory tract. Projection sites of the accessory bulb include the bed nucleus of the accessory olfactory tract and layer IA of the medial nucleus and the posteromedial cortical nucleus of the amygdala (periamygdaloid areas 3, 4, PAM, caudal half of 2, 6 of Rose, '31). An additional accessory bulb efferent projection was found to enter the stria terminalis at the level of the medial amygdaloid nucleus and could be traced to a posterior segment of the bed nucleus of the stria terminalis. The autoradiographic findings indicate that the accessory olfactory bulb connects with portions of the amygdala that do not receive afferent input from the main olfactory bulb and provide evidence for the existence of two distinct and separate olfactory systems.
Monolithic Integration of Surface Plasmon Detector and Metal–Oxide–Semiconductor Field-Effect Transistors (2013)

The monolithic integration of a silicon-based plasmonic detector with metal- oxide-semiconductor field-effect transistors (MOSFETs) was demonstrated. The plasmonic detector consisted of a gold film with a nanoslit grating on a silicon substrate and was operated at a free-space wavelength of 1550 nm. The structure of the nanoslit grating was optimized by using the finite-difference time-domain method. The output current from the plasmonic detector was amplified by ~14 000 times using the monolithically integrated MOSFETs. In addition, dynamic operation of the integrated circuit was demonstrated by modulation of the intensity of a beam that was incident to the plasmonic detector.
A brief taxonomy of intrusion detection strategies (2012)

This paper provide a brief taxonomy and literature review regarding intrusion detection. It highlights the two main methods of classifying intrusion detection systems: network-based v. host-based and anomaly detection v. signature/misuse detection. An extensive bibliography is provided as a starting point for research in the field of intrusion detection.
Resilient Hybrid SatCom and Terrestrial Networking for Unmanned Aerial Vehicles (2020)

Today, Unmanned Aerial Vehicles (UAVs) are widely used in many different scenarios including search, monitoring, inspection, and surveillance. To be able to transmit the sensor data from the UAVs to the destination reliably within tangible response times to the relevant content is crucial, especially for tactical use cases. In this paper, we propose network coded torrents (NECTOR) to leverage multiple network interfaces for resilient hybrid satellite communications (SatCom) and terrestrial networking for UAVs. NECTOR is significantly different from the state-of-the-art multipath protocols such as multipath TCP (MPTCP) as it does not require any additional packet scheduler, rate-adaptation or forward error correction. We present the design and implementation of NECTOR, and evaluate its performance compared to MPTCP. Our experimental results show that NECTOR provides goodput (up to 70%) higher than MPTCP with 5.49 times less signaling overhead.
Study Applicable for Multi-Linear Regression Analysis and Logistic Regression Analysis (2014)

Current study focus on using method of multi-linear regression analysis and logistic regression analysis, and discuss about the condition and scope of multi-linear regression analysis and logistic regression analysis. A modeling method has been introduced keeping in the basic principles of multi-linear regression analysis and logistic regression analysis. The modeling method and two forms of analytic methods have been analyzed, based on two clinic test data of diabetes and Model-2 diabetes as objects of study in combination with the analytic methods of multi-linear regression and logistic regression. Analysis result indicate that glycosylated hemoglobin, glycerin trilaurate, total cholesterol of serum and blood sugar concentration present obvious positive relation (P < 0.05), whereas insulin and blood sugar present negative relation(P < 0.05); body mass index (BMI) and relative factors are dangerous; physical excise and relative factors are protective. In conclusion, multi-linear regression analysis and logistic regression analysis respectively have their own emphasis; for example, multi-linear regression analysis emphasizes on analyzing linear dependent relation with an dependent variable and multiple independent variables, whereas logistic regression analysis emphasizes on analyzing the relation between probability of occurring an incident and independent variables.
L’espace public de la criminalité féminine (2010)

Dans le projet de ce colloque, il est souligné : « Il s’agit de comprendre comment la criminalité féminine a été culturellement forgée depuis l’Antiquité jusqu’à nos jours. » Il s’agirait donc, ajoute la note d’intention, d’une représentation de la femme coupable chargée d’une sorte d’intemporalité. De plus, il serait aussi question d’un imaginaire tenace. Il est bien évident qu’il s’agit ici de femmes criminelles, et non pas de femmes en désordres, en émeutes ou débauchées, ni même violentes...
Total Oxidation of Hydrocarbons on Perovskite Oxides (1992)

Abstract Perovskite-type oxides containing transition metals are attracting great attention as catalysts for complete oxidation of hydrocarbons as well as electrochemical reduction of oxygen (1). A s far as I know, the use of perovskite-type oxides as catalysts was first reported by Meadowcroft in 1970 (2) for the electrochemical reduction of oxygen. Soon after that, Voorhoeve et al. (3) reported the high catalytic activity of perovskite oxides for heterogeneous oxidation. These studies triggered many studies thereafter which are related to exhaust control catalysts and electrode catalysts.
Supramolecular Nanorods of (N-Methylpyridyl) Porphyrin With Captisol: Effective Photosensitizer for Anti-bacterial and Anti-tumor Activities (2019)

Porphyrins, especially the 5,10,15,20-tetrakis(4-<i>N</i>-methylpyridyl) porphyrin (TMPyP), are well-accepted as photosensitizers due to strong absorption from visible to near-infrared region, good singlet oxygen quantum yields as well as chemical versatility, all of which can be further modulated through planned supramolecular strategies. In this study, we report the construction of supramolecular nanorods of TMPyP dye/drug with captisol [sulfobutylether-β-cyclodextrin (SBE<sub>7</sub>βCD)] macrocycle through host-guest interaction. The availability of four cationic N-methylpyridyl groups favors multiple binding interaction with the captisol host, building an extended supramolecular assembly of captisol and TMPyP. In addition to the spectroscopic characterizations for the assembly formation, the same has been pictured in SEM and FM images as nanorods of ~10 μm in length or more. Complexation of TMPyP has brought out beneficial features over the uncomplexed TMPyP dye; enhanced singlet oxygen yield, improved photostability, and better photosensitizing effect, all supportive of efficient photodynamic therapy activity. The Captisol:TMPyP complex displayed enhanced antibacterial activity toward <i>E. coli</i> under white light irradiation as compared to TMPyP alone. Cell viability studies performed in lung carcinoma A549 cells with light irradiation documented increased cytotoxicity of the complex toward the cancer cells whereas reduced dark toxicity is observed toward normal CHO cells. All these synergistic effects of supramolecular nanorods of Captisol-TMPyP complex make the system an effective photosensitizer and a superior antibacterial and antitumor agent.
Fretting Wear (1990)

<div class="htmlview paragraph">Fretting wear is the wear phenomenon occurring between two surfaces having oscillatory relative motion of small amplitude. Besides being a form of wear, fretting can have a deleterious effect on the fatigue life of parts which are subjected to it. The treatise includes a brief discussion concerning the nature of surfaces in contact, followed by an explanation of the fretting process. Various methods of fretting prevention and alleviation are discussed. Three fretting failure case histories are included, 51 references are utilized.</div>
A nanoparticle-incorporated STING activator enhances antitumor immunity in PD-L1–insensitive models of triple-negative breast cancer (2018)

Triple-negative breast cancer (TNBC) has few therapeutic options, and alternative approaches are urgently needed. Stimulator of IFN genes (STING) is becoming an exciting target for therapeutic adjuvants. However, STING resides inside the cell, and the intracellular delivery of CDNs, such as cGAMP, is required for the optimal activation of STING. We show that liposomal nanoparticle-delivered cGAMP (cGAMP-NP) activates STING more effectively than soluble cGAMP. These particles induce innate and adaptive host immune responses to preexisting tumors in both orthotopic and genetically engineered models of basal-like TNBC. cGAMP-NPs also reduce melanoma tumor load, with limited responsivity to anti-PD-L1. Within the tumor microenvironment, cGAMP-NPs direct both mouse and human macrophages (M), reprograming from protumorigenic M2-like phenotype toward M1-like phenotype; enhance MHC and costimulatory molecule expression; reduce M2 biomarkers; increase IFN-γ-producing T cells; augment tumor apoptosis; and increase CD4+ and CD8+ T cell infiltration. Activated T cells are required for tumor suppression, as their depletion reduces antitumor activity. Importantly, cGAMP-NPs prevent the formation of secondary tumors, and a single dose is sufficient to inhibit TNBC. These data suggest that a minimal system comprised of cGAMP-NP alone is sufficient to modulate the tumor microenvironment to effectively control PD-L1-insensitive TNBC.
A Design and Validation System for Asynchronous Circuits (1995)

Article A design and validation system for asynchronous circuits Share on Authors: Peter Vanbekbergen Synopsys, Inc., Mountain View, CA Synopsys, Inc., Mountain View, CAView Profile , Albert Wang Synopsys, Inc., Mountain View, CA Synopsys, Inc., Mountain View, CAView Profile , Kurt Keutzer Synopsys, Inc., Mountain View, CA Synopsys, Inc., Mountain View, CAView Profile Authors Info & Claims DAC '95: Proceedings of the 32nd annual ACM/IEEE Design Automation ConferenceJanuary 1995 Pages 725–730https://doi.org/10.1145/217474.217618Online:01 January 1995Publication History 7citation265DownloadsMetricsTotal Citations7Total Downloads265Last 12 Months1Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Adaptive over current protection for distribution feeders with distributed generators (2005)

The connection of distributed generators (DG) to distribution networks influences the performance of the networks. This paper focuses on the impact of DG on the feeder protection, specifically the impact on the overcurrent (OC) relay performance. The paper presents simulation results to show the extent of deterioration a DG can cause on the OC relay performance. The paper then presents an approach to solve this problem and restore the overcurrent relay performance.
A Novel View of the Adult Stem Cell Compartment From the Perspective of a Quiescent Population of Very Small Embryonic-Like Stem Cells (2017)

Evidence has accumulated that adult hematopoietic tissues and other organs contain a population of dormant stem cells (SCs) that are more primitive than other, already restricted, monopotent tissue-committed SCs (TCSCs). These observations raise several questions, such as the developmental origin of these cells, their true pluripotent or multipotent nature, which surface markers they express, how they can be efficiently isolated from adult tissues, and what role they play in the adult organism. The phenotype of these cells and expression of some genes characteristic of embryonic SCs, epiblast SCs, and primordial germ cells suggests their early-embryonic deposition in developing tissues as precursors of adult SCs. In this review, we will critically discuss all these questions and the concept that small dormant SCs related to migratory primordial germ cells, described as very small embryonic-like SCs, are deposited during embryogenesis in bone marrow and other organs as a backup population for adult tissue-committed SCs and are involved in several processes related to tissue or organ rejuvenation, aging, and cancerogenesis. The most recent results on successful ex vivo expansion of human very small embryonic-like SC in chemically defined media free from feeder-layer cells open up new and exciting possibilities for their application in regenerative medicine.
Infrared emitters and photodetectors with InAsSb bulk active region (2013)

Bulk unrelaxed InAsSb alloys with Sb compositions up to 44 % and layer thicknesses up to 3 µm were grown by molecular beam epitaxy. The alloys showed photoluminescence (PL) energies as low as 0.12 eV at T = 13 K. The electroluminescence and quantum efficiency data demonstrated with unoptimized barrier heterostructures at T= 80 and 150 K suggested large absorption and carrier lifetimes sufficient for the development of long wave infrared detectors and emitters with high quantum efficiency. The minority hole transport was found to be adequate for development of the detectors and emitters with large active layer thickness.
The V3 Loop-Mimicking Pseudopeptide 5[K psi(CH2N)PR]- TASP Inhibits HIV Infection in Primary Macrophage Cultures (1999)

The V3 loop-mimicking pseudopeptide 5[Kpsi(CH2N)PR]-TASP [psi(CH2N) representing a reduced peptide bond], which presents pentavalently the tripeptide Kpsi(CH2N)PR, is a potent inhibitor of HIV entry. By its capacity to bind specifically protein components on the cell surface, 5[Kpsi(CH2N)PR]-TASP blocks the attachment of virus particles to permissive CD4+ cells. Here, the inhibitory effect of 5[Kpsi(CH2N)PR]-TASP was investigated in monocyte-derived macrophages (MDMs) infected by the monocytotropic HIV-1(Ba-L) isolate. We show that 5[Kpsi(CH2N)PR]-TASP inhibits HIV-1(Ba-L) infection in a dose-dependent manner, with more than 90% inhibition at 2 microM concentration. On the other hand, the control 5[QPQ]-TASP construct and the monovalent Kpsi(CH2N)PR tripeptide have no effect even at high concentrations. Under such experimental conditions, the biotin-labeled 5[Kpsi(CH2N)PR]-TASP, but not the Kpsi(CH2N)PR construct, binds specifically to the surface of MDMs and forms a stable complex with the cell surface-expressed nucleolin, as has been demonstrated to be the case in peripheral blood mononuclear cells. Infection of MDMs by HIV-1(Ba-L) could also be inhibited by beta-chemokines RANTES and MIP-1beta. Interestingly, association of low concentrations of 5[Kpsi(CH2N)PR]-TASP and beta-chemokines results in a synergistic inhibitory effect on HIV infection compared with the effect observed with each reagent alone. The inhibitory effect of 5[Kpsi(CH2N)PR]-TASP in primary macrophage cultures point out its potential as an anti-HIV drug in cells, which are the natural viral targets.
Green chemistry: today (and tomorrow) (2005)

It is more than 7 years since I wrote my opening article for the first issue of Green Chemistry—“Green chemistry: challenges and opportunities”. In this update article I will present a personal view of how the area has changed—mostly for the better—and what we need to do now. I will consider how the key drivers for major changes in the way that we practise chemistry have strengthened, how the range of relevant research has broadened, how the case studies from industry have increased and, perhaps most importantly, how our appreciation of what green chemistry should mean has matured. I will also be looking ahead at the immediate and longer-term challenges and opportunities as I now see them—in research and in industrial application and also in education and promotion.
Prediction, Detection, and Correction of Faraday Rotation in Full-Polarimetric L-Band SAR Data (2008)

With the synthetic aperture radar (SAR) sensor PALSAR onboard the Advanced Land Observing Satellite, a new full-polarimetric spaceborne L-band SAR instrument has been launched into orbit. At L-band, Faraday rotation (FR) can reach significant values, degrading the quality of the received SAR data. One-way rotations exceeding 25 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">deg</sup> are likely to happen during the lifetime of PALSAR, which will significantly reduce the accuracy of geophysical parameter recovery if uncorrected. Therefore, the estimation and correction of FR effects is a prerequisite for data quality and continuity. In this paper, methods for estimating FR are presented and analyzed. The first unambiguous detection of FR in SAR data is presented. A set of real data examples indicates the quality and sensitivity of FR estimation from PALSAR data, allowing the measurement of FR with high precision in areas where such measurements were previously inaccessible. In examples, we present the detection of kilometer-scale ionospheric disturbances, a spatial scale that is not detectable by ground-based GPS measurements. An FR prediction method is presented and validated. Approaches to correct for the estimated FR effects are applied, and their effectiveness is tested on real data.
Inverted selective plane illumination microscopy ( <i>i</i> SPIM) enables coupled cell identity lineaging and neurodevelopmental imaging in <i>Caenorhabditis elegans</i> (2011)

The Caenorhabditis elegans embryo is a powerful model for studying neural development, but conventional imaging methods are either too slow or phototoxic to take full advantage of this system. To solve these problems, we developed an inverted selective plane illumination microscopy (iSPIM) module for noninvasive high-speed volumetric imaging of living samples. iSPIM is designed as a straightforward add-on to an inverted microscope, permitting conventional mounting of specimens and facilitating SPIM use by development and neurobiology laboratories. iSPIM offers a volumetric imaging rate 30× faster than currently used technologies, such as spinning-disk confocal microscopy, at comparable signal-to-noise ratio. This increased imaging speed allows us to continuously monitor the development of C, elegans embryos, scanning volumes every 2 s for the 14-h period of embryogenesis with no detectable phototoxicity. Collecting ∼25,000 volumes over the entirety of embryogenesis enabled in toto visualization of positions and identities of cell nuclei. By merging two-color iSPIM with automated lineaging techniques we realized two goals: (i) identification of neurons expressing the transcription factor CEH-10/Chx10 and (ii) visualization of their neurodevelopmental dynamics. We found that canal-associated neurons use somal translocation and amoeboid movement as they migrate to their final position in the embryo. We also visualized axon guidance and growth cone dynamics as neurons circumnavigate the nerve ring and reach their targets in the embryo. The high-speed volumetric imaging rate of iSPIM effectively eliminates motion blur from embryo movement inside the egg case, allowing characterization of dynamic neurodevelopmental events that were previously inaccessible.
Evasion of Cellular Ocular Defenses by Contact Lens Isolates of Serratia marcescens (2003)

The ability of S. marcescens to resist phagocytosis and grow to high levels in the presence of PMNs, particularly when grown as a biofilm on contact lenses, may be a mechanism by which this bacterium can survive the ocular host defense system, grow, and cause keratitis or other adverse responses.
Dengue virus neutralization by human immune sera: Role of envelope protein domain III-reactive antibody (2021)

Dengue viruses (DENV) are the etiological agents of dengue fever (DF) and dengue hemorrhagic fever (DHF). The DENV complex consists of four closely related viruses designated DENV serotypes 1 through-4. Although infection with one serotype induces cross reactive antibody to all 4 serotypes, the long term protective antibody response is restricted to the serotype responsible for infection. Cross-reactive antibodies appear to enhance infection during a second infection with a different serotype. The goal of the present study was to characterize the binding specificity and functional properties of human DENV immune sera. The study focused on domain III of the viral envelope protein (EDIII), as this region has a well characterized epitope that is recognized by strongly neutralizing serotype-specific mouse monoclonal antibodies (Mabs). Our results demonstrate that EDIII-reactive antibodies are present in primary and secondary DENV immune human sera. Human antibodies bound to a serotype specific epitope on EDIII after primary infection and a serotype cross reactive epitope on EDIII after secondary infection. However, EDIII-binding antibodies constituted only a small fraction of the total antibody in immune sera binding to DENV. Studies with complete and EDIII antibody depleted human immune sera demonstrated that EDIII binding antibodies play a minor role in DENV neutralization. We propose that human antibodies directed to other epitopes on the virus are primarily responsible for DENV neutralization. Our results have implications for understanding protective immunity following natural DENV infection and for evaluating DENV vaccines.