gebhart/patrepeval huggingface dataset:
If, When, and How to Perform Lane Change Maneuvers on Highways (2016)

Advanced driver assistance systems or highly automated driving systems for lane change maneuvers are expected to enhance highway traffic safety, transport efficiency, and driver comfort. To extend the capability of current advanced driver assistance systems, and eventually progress to highly automated highway driving, the task of automatically determine if, when, and how to perform a lane change maneuver, is essential. This paper thereby presents a low-complexity lane change maneuver algorithm which determines whether a lane change maneuver is desirable, and if so, selects an appropriate inter-vehicle traffic gap and time instance to perform the maneuver, and calculates the corresponding longitudinal and lateral control trajectory. The ability of the proposed lane change maneuver algorithm to make appropriate maneuver decisions and generate smooth and safe lane change trajectories in various traffic situations is demonstrated by simulation and experimental results.
Progressive simplicial complexes (1997)

Article Free Access Share on Progressive simplicial complexes Authors: Jovan Popović Carnegie Mellon University Carnegie Mellon UniversityView Profile , Hugues Hoppe Microsoft Research Microsoft ResearchView Profile Authors Info & Claims SIGGRAPH '97: Proceedings of the 24th annual conference on Computer graphics and interactive techniquesAugust 1997 Pages 217–224https://doi.org/10.1145/258734.258852Published:03 August 1997Publication History 186citation904DownloadsMetricsTotal Citations186Total Downloads904Last 12 Months67Last 6 weeks6 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Ionic Liquids-Based Bitumen Extraction: Enabling Recovery with Environmental Footprint Comparable to Conventional Oil (2019)

A nonaqueous process was developed using ionic liquids (ILs) to extract bitumen from Alberta oil sands at room temperature. Based on an IL design platform of balancing lipophilic/hydrophilic properties with possible interfacial interactions, trialkylamine/fatty acid-based ILs were studied and down-selected considering performance, cost, composition, and interaction with water. The use of protic ILs also allowed modifying the amine/acid composition to increase the bitumen extracted and decrease the solid content in extracted bitumen. Using the IL trioctylammonium oleate ([HN888][Oleate]) at a 1:3 IL/oil sand mass ratio, we were able to achieve bitumen extraction from high-grade Alberta oil sands of ca. 100% with low solids content (<1%) in a fast, low-energy process. Our results demonstrate that the proper design of the IL can lead to efficient oil extraction without conventional solvents, without generating aqueous tailings, and with minimum energy consumption, that is, a production process with environmental impacts comparable to those associated with production of other hydrocarbon resources.
High speed opto-electronic neural network (1990)

The first opto-electronic neural network, employing InGaAs/InP based, multi-quantum well, surface modulator/detector arrays and operating at speeds above l0 M bit/s is reported. The network uses a novel architecture that has a computer generated holographic weight matrix outside the modulator and detector layers.
DPC4 gene mutation in colitis associated neoplasia. (1997)

The DPC4 gene is a target of 18q LOH events in colitis associated neoplasia.
Effects of γ-Turn and β-Tail Amino Acids on Sequence-Specific Recognition of DNA by Hairpin Polyamides (1999)

Three-ring polyamides containing pyrrole (Py) and imidazole (Im) amino acids covalently coupled by a turn-specific γ-aminobutyric acid linker (γ-turn) form six-ring hairpins that recognize predetermined 5-base pair (bp) sequences in the minor groove of DNA. To determine the sequence specificity of the γ-turn and C-terminal β-alanine (β-tail) amino acids, the DNA-binding properties of the hairpin polyamide ImImPy-γ-ImPyPy-β-Dp were analyzed by footprinting and affinity cleavage on DNA-restriction fragments containing the eight possible 5‘-ATGGCNA-3‘ and 5‘-ANGGCTA-3‘ sites (N = A, T, G or C; 5-bp hairpin site is in italics). Quantitative footprint titrations demonstrate that both the γ-turn and β-tail amino acids have a >200−400-fold preference for A·T/T·A relative to G·C base pairs at these positions. Effects of the base pairs adjacent to the 5-bp hairpin-binding site were analyzed by footprinting experiments on a DNA-restriction fragment containing the eight possible 5‘-ATGGCTN-3‘ and 5‘-NTGGCTA-3‘ sites. Quantitative footprint titrations demonstrate that the turn and tail amino acids have reduced specificity (3−20-fold preference) for A·T/T·A relative to G·C base pairs at these positions. These results indicate that the turn and tail amino acids do not simply act as neutral linker residues but, in fact, are sequence-specific recognition elements with predictable DNA-binding specificity.
Hypersensitivity to diphtheria toxin by mouse cells expressing both diphtheria toxin receptor and CD9 antigen. (1993)

DTS-II is a highly diphtheria toxin (DT)-sensitive cell line previously isolated by transfection of wild-type DT-resistant mouse L-M(TK-) cells with the cDNA encoding a monkey Vero cell DT receptor. DTS-II cells are as toxin-sensitive as Vero cells, have approximately 3-fold more receptors than Vero cells, and have approximately 10-fold lower affinity for DT than Vero cells. We now cotransfected DTS-II cells with a plasmid containing the Vero cell cDNA coding for CD9 antigen (pCD9) and with a plasmid containing the gene for hygromycin resistance (pHyg). The stably transfected hygromycin-resistant colonies were screened for DT hypersensitivity employing a replica plate system. A DT-hypersensitive colony was isolated and purified. The purified DT-hypersensitive cells, DTS-III, (i) are approximately 10-fold more toxin-sensitive than DTS-II and Vero cells and (ii) bear approximately 10(6) DT receptors per cell (i.e., approximately 20-fold and approximately 60-fold more receptors than DTS-II and Vero cells, respectively), but their receptor affinity is still approximately 10-fold lower than that of Vero cells. Cross-linking experiments employing 125I-labeled DT demonstrated that DTS-II and DTS-III cells have essentially the same profile of DT-binding cell-surface protein(s), suggesting that CD9 antigen, although expressed on the cell surface of DTS-III cells, may not be in close proximity to the DT-binding domain of the receptor. CD9 may affect DT receptor expression by increasing receptor density at the cell surface. By employing DTS-III cells it should be possible to purify and characterize the DT cell-surface receptor protein(s).
Specific immunoassay of alpha-amylase isoenzymes in human serum. (1985)

Abstract A monoclonal antibody (66C7) was prepared that specifically binds human salivary amylase (EC 3.2.1.1); it cross reacts with human pancreatic amylase by less than 1%. Two procedures are described for determination of isoamylases in human serum with this antibody: an enzyme immunoassay for determining amylase of salivary origin, and a routine method in which this amylase is immunoprecipitated and the remaining (pancreatic) amylase activity is assayed. Results by the two methods correlate well.
Effects of prostaglandin D2 and its analogues on intraocular pressure in rabbits. (1988)

Studies were carried out of the effects of topically applied prostaglandin (PG) D2 and its metabolites and analogues on the intraocular pressure (IOP) in rabbits, and the results were compared with those of studies using PGE2 and F2 alpha. The application of PGD2 (0.4-250 micrograms) reduced the IOP, in a dose-dependent manner without causing a hypertensive phase. The hypotensive effect was observed within 30 minutes after the application and lasted for over 7 hours. Higher doses of PGE2 (10, 50 micrograms) or PGF2 alpha (50 micrograms) caused initial IOP elevation followed by a prolonged hypotensive phase. Lower doses of PGF2 alpha (2, 10 micrograms) caused a prolonged (over 7 hours) reduction in the IOP following a latency of over 2 hours. The IOP reduction by 2 micrograms of PGE2 lasted for 5 hours. No miotic response followed the use of these PG's. Conjunctival and iridal hyperemia, aqueous flare, irritation (defined by lid-closing), and aqueous protein content were examined at equi-hypotensive doses of the three PG's (50 micrograms for PGD2, 2 micrograms for PGE2, and 10 micrograms for PGF2 alpha). PGE2 was the strongest in causing these side effects, followed by PGF2 alpha. PGD2 did not cause any of these responses except for some development of conjunctival hyperemia. All of the 4 PGD2 metabolites were ineffective in reducing IOP. Among 6 PGD2 analogues, BW245C, PGD3, and PGD2 methyl ester more effectively reduced IOP than did PGD2. PGD1 and 16,16-dimethyl PGD2 were not effective.
Secret Key Generation Based on AoA Estimation for Low SNR Conditions (2015)

In the context of physical layer security, a physical layer characteristic is used as a common source of randomness to generate the secret key. Therefore an accurate estimation of this characteristic is the core for reliable secret key generation. Estimation of almost all the existing physical layer characteristic suffer dramatically at low signal to noise (SNR) levels. In this paper, we propose a novel secret key generation algorithm that is based on the estimated angle of arrival (AoA) between the two legitimate nodes. Our algorithm has an outstanding performance at very low SNR levels. Our algorithm can exploit either the Azimuth AoA to generate the secret key or both the Azimuth and Elevation angles to generate the secret key. Exploiting a second common source of randomness adds an extra degree of freedom to the performance of our algorithm. We compare the performance of our algorithm to the algorithm that uses the most commonly used characteristics of the physical layer which are channel amplitude and phase. We show that our algorithm has a very low bit mismatch rate (BMR) at very low SNR when both channel amplitude and phase based algorithm fail to achieve an acceptable BMR.
Federated Learning: Strategies for Improving Communication Efficiency (2016)

Federated Learning is a machine learning setting where the goal is to train a high-quality centralized model while training data remains distributed over a large number of clients each with unreliable and relatively slow network connections. We consider learning algorithms for this setting where on each round, each client independently computes an update to the current model based on its local data, and communicates this update to a central server, where the client-side updates are aggregated to compute a new global model. The typical clients in this setting are mobile phones, and communication efficiency is of the utmost importance. In this paper, we propose two ways to reduce the uplink communication costs: structured updates, where we directly learn an update from a restricted space parametrized using a smaller number of variables, e.g. either low-rank or a random mask; and sketched updates, where we learn a full model update and then compress it using a combination of quantization, random rotations, and subsampling before sending it to the server. Experiments on both convolutional and recurrent networks show that the proposed methods can reduce the communication cost by two orders of magnitude.
Yoghurt production by Lactobacillus fermentation of soybean milk. (1976)

The flavour of a soyabean milk yoghurt was improved by soaking the beans for 16 h in water at 20 deg C, boiling in 0.2% NaHCO3 solution for 5 min, washing, blending with water to give 8:1 water/dry bean ratio, ultrasonic treatment (20 kHz/10 min) and centrifuging (3000 rev/min for 5 min). Effects on the titratable acidity and texture of experimental soyabean yoghurts of addition of cheese whey solids (0-4%), heat treatment (90, 100, 121 deg C for 10 or 20 min) and protein content (2.8-4.5%) are recorded. Best results were obtained by heating together 500 ml soyabean milk, 10 g whey solids and 25 g sucrose at 100 deg C for 20 min, rapid cooling with addition of 1% gelatin (to prevent whey separation) and desired flavouring (e.g. lemon), 5% inoculation with a 1:1 mixture of B-1910 and B-2092 Lactobacillus acidophilus, and incubation at 37 deg C for 24 h. Taste panel evaluation of the yoghurt was favourable, with a score of 6.0 (of 10) vs. 4.5 for yoghurt from traditional soya milk.
Carbonate Fuel Cell Anode: A Review (2014)

Porous nickel alloyed anodes (Ni-Al and / or Ni-Cr) have demonstrated excellent mechanical, chemical and electrochemical stability during MCFC stack endurance tests. These electrodes showed no discernible change in the morphologies, pore structure and particles size. Combination of polarization studies and different diagnostic techniques showed that the anode reaction is primarily under mass-transfer control. Improved anode structure with balanced pores for gas diffusion and electrolyte retention was developed. The current focus of technology development is on improving wettability, reducing anode material cost and improving the manufacturing process
Multi-pulse speech coder (1992)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Nikolaos Gouvianakis, Costas Xydeas; Multi‐pulse speech coder. J. Acoust. Soc. Am. 1 November 1992; 92 (5): 3028. https://doi.org/10.1121/1.404305 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAcoustical Society of AmericaThe Journal of the Acoustical Society of America Search Advanced Search |Citation Search
Biomarkers of IgE- and IgG-dependent anaphylaxis (86.20) (2010)

Abstract Anaphylaxis is classically induced by IgE-dependent FceRI crosslinking that triggers mast cell and basophil mediator, enzyme and cytokine secretion. Anaphylaxis can also be induced in mice, however, by IgG- mediated crosslinking of macrophage and basophil FcgRIII. This alternative pathway may be responsible for some cases of human anaphylaxis, particularly those associated with protein-based drugs, including humanized mAbs. We used mouse passive anaphylaxis models to attempt to identify markers that could distinguish between IgE- and IgG-mediated anaphylaxis. Mice sensitized by i.v. injection of TNP-specific IgE or IgG mAbs were challenged i.v. 24h later with TNP-OVA; changes in cells and serum were then evaluated. Changes 2h post-challenge in both IgE- and IgG-mediated anaphylaxis included: 1) up to 90% decreases in percentages of basophils and monocytes in blood; 2) doubling of the percentage of neutrophils in blood; and 3) ~25% increases in the ability of neutrophils to generate reactive oxygen intermediates and mobilize Ca++. IgE-, but not IgG-mediated anaphylaxis induced greatly increased serum levels of IL-4 and MMCP1 and an ~30% increase in T cell membrane IL-4Ralpha 4 h post-challenge, while IgG-, but not IgE-dependent anaphylaxis decreased neutrophil membrane FcgRIIb/RIII expression by ~30% 2-12 h post-challenge. Studies will be performed to determine if these cellular markers can distinguish between IgE-dependent and putative IgG-dependent anaphylaxis in humans.
Activity of Abundant Antimicrobials of the Human Airway (1999)

Human airways produce several antimicrobial factors; the most abundant are lysozyme and lactoferrin. Despite their likely importance in preventing infection, and their possible key role in the pathogenesis of cystic fibrosis (CF), we know little about their antibacterial activity in the context of the CF airway. We found that abundant airway antimicrobial factors kill common CF pathogens, although Burkholderia was relatively resistant. To study the antibacterial activity, we developed a rapid, sensitive, and quantitative in vitro luminescence assay. Because NaCl concentrations may be elevated in CF airway surface liquid, we tested the effect of salt on antibacterial activity. Activity of individual factors and of airway lavage fluid was inhibited by high ionic strength, and it was particularly sensitive to divalent cations. However, it was not inhibited by nonionic osmolytes and thus did not require hypotonic liquid. The inhibition by ionic strength could be partially compensated by increased concentrations of antibacterial factors, thus there was no one unique salt concentration for inhibition. CF airway secretions also contain abundant mucin and elastase; however, these had no effect on antibacterial activity of lysozyme, lactoferrin, or airway lavage fluids. When studied at low NaCl concentrations, CF and non-CF airway lavage fluids contained similar levels of antibacterial activity. These results suggest approaches toward developing treatments aimed at preventing or reducing airway infections in individuals with CF.
Development of tunable terahertz wire lasers (2010)

We report a novel tuning mechanism based on a “wire-laser” with subwavelength transverse dimensions(w≪λ). By manipulating the waveguided mode propagating outside the cavity, frequency tuning of ~137GHz (3.6%) is demonstrated from a single-laser device at ~3.8THz.
Digital lithographic processing for large‐area electronics (2007)

Abstract— A non‐contact jet‐printed mask‐patterning process is described. By combining digital imaging with jet printing, digital lithography was used to pattern a‐Si:H‐based electronics on glass and plastic substrates in place of conventional photolithography. This digital lithographic process is capable of layer‐to‐layer registration of ±5 μm using electronic mask files that are directly jet printed onto a surface. Aminimum feature size of 50 μm was used to create 180 × 180 element backplanes having 75‐dpi resolution for display and image‐sensor applications. By using a secondary mask process, the minimum feature size can be reduced down to ∼15 μm for fabrication of short‐channel thin‐film transistors. The same process was also used to pattern black‐matrix wells in fabricating color‐filter top plates in LCD panels.
Metabolic evolution and <sup>13</sup>C flux analysis of a succinate dehydrogenase deficient strain of <i>Yarrowia lipolytica</i> (2016)

Bio-based succinic acid production can redirect industrial chemistry processes from using limited hydrocarbons to renewable carbohydrates. A fermentation process that does not require pH-titrating agents will be advantageous to the industry. Previously, a Yarrowia lipolytica strain that was defective for succinate dehydrogenase was constructed and was found to accumulate up to 17.5 g L(-1) of succinic acid when grown on glycerol without buffering. Here, a derivative mutant was isolated that produced 40.5 g L(-1) of succinic acid in 36 h with a yield of 0.32 g g(-1) glycerol. A combination approach of induced mutagenesis and metabolic evolution allowed isolation of another derivative that could utilize glucose efficiently and accumulated 50.2 g L(-1) succinic acid in 54 h with a yield of 0.43 g g(-1) . The parent strain of these isolated mutants was used for [1,6-(13) C2 ]glucose assimilation analysis. At least 35% glucose was estimated to be utilized through the pentose phosphate pathway, while ≥84% succinic acid was formed through the oxidative branch of the tricarboxylic acid cycle. Biotechnol. Bioeng. 2016;113: 2425-2432. © 2016 Wiley Periodicals, Inc.
Relationship of the human immunodeficiency virus type 1 gp120 third variable loop to a component of the CD4 binding site in the fourth conserved region (1992)

Neutralizing antibodies that recognize the human immunodeficiency virus gp120 exterior envelope glycoprotein and are directed against either the third variable (V3) loop or conserved, discontinuous epitopes overlapping the CD4 binding region have been described. Here we report several observations that suggest a structural relationship between the V3 loop and amino acids in the fourth conserved (C4) gp120 region that constitute part of the CD4 binding site and the conserved neutralization epitopes. Treatment of the gp120 glycoprotein with ionic detergents resulted in a V3 loop-dependent masking of both linear C4 epitopes and discontinuous neutralization epitopes overlapping the CD4 binding site. Increased recognition of the native gp120 glycoprotein by an anti-V3 loop monoclonal antibody, 9284, resulted from from single amino acid changes either in the base of the V3 loop or in the gp120 C4 region. These amino acid changes also resulted in increased exposure of conserved epitopes overlapping the CD4 binding region. The replication-competent subset of these mutants exhibited increased sensitivity to neutralization by antibody 9284 and anti-CD4 binding site antibodies. The implied relationship of the V3 loop, which mediates post-receptor binding steps in virus entry, and components of the CD4 binding region may be important for the interaction of these functional gp120 domains and for the observed cooperativity of neutralizing antibodies directed against these regions.
Sub-80-nm contact hole patterning using Step and Flash Imprint Lithography (2004)

Recently, the International Roadmap for Semiconductors (ITRS) has included imprint lithography on its roadmap, to be ready for production use in 2013 at the 32 nm node. Step and Flash Imprint Lithography (S-FIL<sup>TM</sup>) is one of the promising new methods of imprint lithography being actively developed. Since S-FIL is a 1X printing technique, fabrication of templates is especially critical. S-FIL has previously demonstrated the ability to reliably print high resolution line/space and contact hole features into a silicon-rich etch barrier material. Beyond printing with S-FIL however, there is the requirement to develop low or zero bias, high selectivity dry etch processes needed to transfer printed images into the substrate. In this study, the feasibility and methodology of imprinting sub-80 nm contacts, and pattern transferring this image into an underlying oxide layer is demonstrated. Critical parameters such as e-beam dose and etch biases associated with template pillar fabrication, and biases associated with pattern transfer processes for sub-80 nm 1:1 and 1:2 pitch contacts are discussed. Wafer imprinting was done on 200 mm wafers using Molecular Imprints Inc., Imprio 100<sup>TM</sup> system.
Ventralis Intermedius plus Ventralis Oralis Anterior and Posterior Deep Brain Stimulation for Posttraumatic Holmes Tremor: Two Leads May Be Better than One: Technical Note (2005)

The patient experienced tremor rebound with VIM-VOP monotherapy. However, when the second lead (VOA/VOP) was activated, he experienced sustained improvement in tremor and tremor disability at a 12-month follow-up examination. This case elucidates a potential new approach for the treatment of patients with posttraumatic Holmes tremor. Additional study and longer follow-up periods will be needed to further evaluate this promising therapy.