gebhart/patrepeval huggingface dataset:
Weapon Detection using Artificial Intelligence and Deep Learning for Security Applications (2020)

Security is always a main concern in every domain, due to a rise in crime rate in a crowded event or suspicious lonely areas. Abnormal detection and monitoring have major applications of computer vision to tackle various problems. Due to growing demand in the protection of safety, security and personal properties, needs and deployment of video surveillance systems can recognize and interpret the scene and anomaly events play a vital role in intelligence monitoring. This paper implements automatic gun (or) weapon detection using a convolution neural network (CNN) based SSD and Faster RCNN algorithms. Proposed implementation uses two types of datasets. One dataset, which had pre-labelled images and the other one is a set of images, which were labelled manually. Results are tabulated, both algorithms achieve good accuracy, but their application in real situations can be based on the trade-off between speed and accuracy.
Molecular quantum wake-induced pulse shaping and extension of femtosecond air filaments (2012)

Two-pulse excitation of a molecular quantum wake in air during filamentary propagation is shown to controllably shape an intense femtosecond probe pulse and to significantly extend the filament compared to single-pulse excitation. The effect is sensitive to pump-probe delay on a \ensuremath{\sim}10-fs time scale.
Dependence of the differentiated state on the cellular environment: modulation of collagen synthesis in tendon cells. (1977)

In an adequate environment, primary avian tendon cells are capable of retaining both the full expression of differentiated function and a correct morphological orientation for 1 week in culture. At high density and in the presence of ascorbate, they are fully stabilized in that they devote 25-30% of their total protein synthesis to collagen, a level comparable to that in tendon cells in ovo. However, either at low density or in medium without ascorbate, they synthesize collagen at only a third of this level. If plated on a collagen matrix, these cells will orient themselves in a manner similar to that of tendon cells in vivo. Furthermore, they are capable of fully modulating the percentage of collagen synthesis upon addition or removal of ascorbate and serum. The variation in the percentage of collagen produced is a result of alterations in collagen synthesis rather than of changes in total protein synthesis or hydroxylation of proline in collagen. Primary avian tendon cells, therefore, provide a suitable model for understanding the stability of the differentiated state, the mechanism of action of ascorbate, and the regulation of collagen biosynthesis.
Simplified iterative detection of serially concatenated CPM signals (2005)

In this paper, we derive low-complexity MAP symbol detection algorithms for continuous phase modulations (CPMs). To obtain this result, the well-known problem of a transmission over an additive white Gaussian noise (AWGN) channel affected by known intersymbol interference (ISI) is first considered. We show that the maximum a posteriori (MAP) symbol detection strategy, usually implemented by using the Forney observation model, can be equivalently implemented based on the samples at the output of a filter matched to the received pulse, i.e., based on the Ungerboeck observation model. Although interesting from a conceptual viewpoint, the derived algorithm has a practical relevance in turbo equalization schemes for partial response signalling, where the implementation of a whitening filter can be avoided, and in the derivation of the simplified algorithms for CPM signals.
RF Compression of sub-relativistic space-charge-dominated electron bunches for single-shot femtosecond electron diffraction (2011)

We demonstrate radiofrequency compression by more than 2 orders of magnitude of 95 keV space-charge-dominated ellipsoidal electron bunches to sub-100 fs durations1*,**.These bunches have sufficient charge and are of sufficient quality to capture a diffraction pattern with a single shot, which we demonstrate by a diffraction experiment on a polycrystalline gold foil.The compression results from velocity bunching after inversion of the positive space-charge-induced velocity chirp.This inversion is induced by the oscillatory longitudinal electric field of a 3 GHz radio-frequency cavity.The arrival time jitter is measured to be 80 fs.
Continuous Infusion or Intravenous Bolus: What Is the Rationale for Doxorubicin Administration? (1987)

In order to achieve a better therapeutic index of anticancer drugs, numerous authors are using continuous infusion therapy rather than classical intravenous bolus injection. In the case of doxorubicin or daunorubicin numerous experimental data have been published, which could provide a rationale to this clinical problem. However, due to the variety of the approaches used, the results are inconsistent and no definitive conclusion can be drawn. Several clinical phase I and II trials have been performed since 1980; they show that the toxicity of doxorubicin may be reduced by the use of continuous infusion, but the preservation of the efficacy of the drug has never been proved. Comparative phase III trials are required before this schedule of administration become routine procedure for this drug.
Optimization of Wind Farm Micro Sitting Based on Genetic Algorithm (2011)

In order to increase wind energy utilization efficiency by the optimization of the wind farm micro sitting, a method which could calculate the wind farm velocity is proposed by consideration of multi turbines wake loss and superposition. Based on the given velocity data of a wind farm, the maximal annual energy production is set as the optimal objective and the ordinates of wind turbines would be the optimal variables, micro sittings of the wind farm turbines are optimized by genetic algorithm. Layout calculation result of the optimal method is quite similar to that of other successful search method, but higher efficiency is reached, and the micro sitting layout is agreement with the regular plum-type layout. Annual energy productions are also calculated under the condition of different wind turbine number. Results show annual energy production increases with the wind turbine number increased, but the increasing trend is lower and lower. The research could provide a reference to wind farm micro-sitting.
Impact of the addition of different plant residues on nitrogen mineralization–immobilization turnover and carbon content of a soil incubated under laboratory conditions (2015)

Abstract. Application of plant residues as soil amendment may represent a valuable recycling strategy that affects carbon (C) and nitrogen (N) cycling in soil–plant systems. The amount and rate of nutrient release from plant residues depend on their quality characteristics and biochemical composition. A laboratory incubation experiment was conducted for 120 days under controlled conditions (25 °C and 58% water-filled pore space) to quantify initial biochemical composition and N mineralization of leguminous and non-leguminous plant residues, i.e., the roots, shoots and leaves of Glycine max, Trifolium repens, Zea mays, Populus euramericana, Robinia pseudoacacia and Elaeagnus umbellata, incorporated into the soil at the rate of 200 mg residue N kg−1 soil. The diverse plant residues showed a wide variation in total N, C, lignin, polyphenols and C / N ratio with higher polyphenol content in the leaves and higher lignin content in the roots. The shoot of Glycine max and the shoot and root of Trifolium repens displayed continuous mineralization by releasing a maximum of 109.8, 74.8 and 72.5 mg N kg−1 and representing a 55, 37 and 36% recovery of N that had been released from these added resources. The roots of Glycine max and Zea mays and the shoot of Zea mays showed continuous negative values throughout the incubation. After an initial immobilization, leaves of Populus euramericana, Robinia pseudoacacia and Elaeagnus umbellata exhibited net mineralization by releasing a maximum of 31.8, 63.1 and 65.1 mg N kg−1, respectively, and representing a 16, 32 and 33% N recovery, respectively. Nitrogen mineralization from all the treatments was positively correlated with the initial residue N contents (r = 0.89; p &amp;leq; 0.01) and negatively correlated with lignin content (r = −0.84; p ≤ 0.01), C / N ratio (r = −0.69; p ≤ 0.05), lignin / N ratio (r = −0.68; p ≤ 0.05), polyphenol / N ratio (r = −0.73; p ≤ 0.05) and (lignin + polyphenol) : N ratio (r = −0.70; p ≤ 0.05) indicating a significant role of residue chemical composition and quality in regulating N transformations and cycling in soil. The present study indicates that incorporation of plant residues strongly modifies the mineralization–immobilization turnover (MIT) of soil that can be taken into account to develop synchronization between net N mineralization and crop demand in order to maximize N delivery and minimize N losses.
Resolvents (1993)

The concept of the resolvent which is central for the theory of linear Volterra equations is introduced and discussed. It is applied to the inhomogeneous equation to derive various variation of parameters formulas. The main tools for proving existence theorems for the resolvent are described in detail; these methods are the operational calculus in Hilbert spaces, perturbation arguments, and the Laplace-transform method. The generation theorem, the analog of the Hille-Yosida theorem of semigroup theory for Volterra equations, proved in Section 1.5, is of fundamental importance in later chapters. The theory is completed with several counterexamples, and with a discussion of the integral resolvent.
MicroRNA Expression Profile on Solid Subtype of Invasive Lung Adenocarcinoma Reveals a Panel of Four miRNAs to Be Associated with Poor Prognosis in Chinese Patients (2016)

According to the reclassification of lung adenocarcinoma (LAC) proposed in 2011, solid predominant lung adenocarcinoma (SPA) has been associated with poor outcomes for LAC patients. However, the prognostic value of the presence of solid subtype remains unclear. Besides, there is little data about the roles of microRNA (miRNA) in solid subtype of LAC. In this study, 243 LAC patients were classified into solid subtype positive and negative groups (S+ LAC, n=134 and S- LAC, n=109) according to whether the solid subtype was more than 5% of the tumor component or not. We analyzed the relationship between solid subtype and patients' outcome by univariate and multivariate analyses. Solid subtype was proved to be significantly associated with the 5-year overall survival and played as an independent prognostic factor for stage I-III invasive LAC patients. Then miRNA microarray was used to identify differentially expressed miRNAs in solid subtype, resulting in 31 differential miRNAs. Quantitative reverse transcription-PCR (QRT-PCR) was used to validate 4 key miRNAs (miR-133b, miR-155-5p, miR-124-3p, miR-145-5p). Further, CCK-8 and transwell assays were performed to validate the impact of one dysregulated miRNA (miR-133b) on LAC cell function. Interestingly, while miR-133b could significantly inhibit the proliferation of A549 and SPC-A1, it showed no effect on the migration or invasion of LAC cell lines. These results suggest that solid subtype can exert independent prognostic impact on LAC patients, and 4 important dysregulated miRNAs in solid subtype of LAC may be involved in the malignancy of S+LAC, thus may further have clinical perspective for S+ LAC in the future.
Inhibition of Th2 Differentiation and GATA-3 Expression by BCL-6 (2003)

The B cell lymphoma (BCL)-6 transcriptional repressor protein is an important regulator of Th2 responses. Mice deficient in BCL-6 develop severe Th2-type inflammation that can develop even in the absence of IL-4 signaling. We have investigated the mechanism for how BCL-6 regulates Th2 cell differentiation and have found that IL-6 signaling can promote dramatically increased levels of Th2 differentiation in BCL-6(-/-) CD4 T cells compared with wild-type CD4 T cells. IL-6 can induce a low level of Th2 cytokine expression in BCL-6(-/-)STAT6(-/-) cells but not in STAT6(-/-) cells. Since the promoters for Th2 cytokines such as IL-4, IL-5, IL-10, and IL-13 do not contain consensus BCL-6 DNA binding sites, we investigated whether BCL-6 might regulate the GATA-3 transcription factor that activates the expression of multiple Th2 cytokines. Consistent with the idea that BCL-6 represses GATA-3 expression, we found that GATA-3 levels are up-regulated in BCL-6(-/-)STAT6(-/-) CD4 T cells compared with STAT6(-/-) CD4 T cells. Retrovirus-mediated expression of BCL-6 in BCL-6(-/-)STAT6(-/-) T cells as well as developing wild-type Th2 cells leads to a potent repression of IL-4 and IL-10 secretion. Retrovirus-mediated expression of BCL-6 in both BCL-6(-/-)STAT6(-/-) and wild-type T cells also leads to a significant decrease in GATA-3 protein levels. Surprisingly, BCL-6 does not appear to regulate GATA-3 mRNA levels and thus BCL-6 appears to regulate GATA-3 expression at a posttranscriptional level. Regulation of GATA-3 protein levels is likely a key mechanism for how BCL-6 regulates Th2 cytokine expression and Th2 differentiation independently of STAT6. These data also point to a novel regulatory mechanism for BCL-6 separate from transcriptional repression.
Carrier concentration dependence of band gap shift in n-type ZnO:Al films (2007)

Al-doped ZnO (AZO) thin films have been prepared by mist chemical vapor deposition and magnetron sputtering. The band gap shift as a function of carrier concentration in n-type zinc oxide (ZnO) was systematically studied considering the available theoretical models. The shift in energy gap, evaluated from optical absorption spectra, did not depend on sample preparations; it was mainly related to the carrier concentrations and so intrinsic to AZO. The optical gap increased with the electron concentration approximately as ne2∕3 for ne≤4.2×1019 cm−3, which could be fully interpreted by a modified Burstein–Moss (BM) shift with the nonparabolicity of the conduction band. A sudden decrease in energy gap occurred at 5.4−8.4×1019 cm−3, consistent with the Mott criterion for a semiconductor-metal transition. Above the critical values, the band gap increased again at a different rate, which was presumably due to the competing BM band-filling and band gap renormalization effects, the former inducing a band gap widening and the latter an offsetting narrowing. The band gap narrowing (ΔEBGN) derived from the band gap renormalization effect did not show a good ne1∕3 dependence predicated by a weakly interacting electron-gas model, but it was in excellent agreement with a perturbation theory considering different many-body effects. Based on this theory a simple expression, ΔEBGN=Ane1∕3+Bne1∕4+Cne1∕2, was deduced for n-type ZnO, as well as p-type ZnO, with detailed values of A, B, and C coefficients. An empirical relation once proposed for heavily doped Si could also be used to describe well this gap narrowing in AZO.
Platelet deactivation by 5HT2receptor blockade parallels the antihypertensive response to ketanserin (1989)

Serotonin (5HT) has been implicated in thromboembolic complications and blood pressure elevation and both may be reduced with the 5HT2-receptor blocker ketanserin. In 17 patients with essential hypertension (WHO I and II, diastolic pressure V greater than or equal to 100 mmHg) blood pressure, platelet 5HT uptake, content and release as well as 5HT-induced shape change and aggregation were measured before and immediately after 8 weeks oral ketanserin at 20-40 mg twice daily. During ketanserin therapy, platelet 5HT release, shape change reaction and aggregation to 5HT were significantly reduced by more than 50%. These platelet effects were more pronounced in patients responsive to ketanserin (greater than or equal to 10% decrease of diastolic pretreatment pressure) and the fall in diastolic pressure correlated with the inhibition of 5HT-induced aggregation as well as the change in 5-hydroxy-indoleacetic acid (5HIAA) in platelet-rich plasma (PRP; P less than 0.05). Serotonin-receptor-independent platelet events were not affected by ketanserin. Ketanserin corrects 5HT2-receptor-mediated platelet function along with the reduction of blood pressure.
Polyamines Differentially Inhibit Cyclic AMP‐Dependent Protein Kinase‐Mediated Phosphorylation in the Brain of the Tobacco Hornworm, <i>Manduca sexta</i> (1988)

The effects of the naturally occurring polyamines spermine and spermidine on phosphorylation promoted by cyclic AMP (cAMP)-dependent protein kinase (PK) (cAMP-PK; EC 2.7.1.37) were studied using the brain of the tobacco hornworm, Manduca sexta. Four particulate-associated peptides (280, 34, 21, and 19 kilodaltons) in day 1 pupal brains are endogenous substrates for a particulate type II cAMP-PK. These phosphoproteins are present in brain synaptosomal, as well as microsomal, particulate fractions but are not present in the cytosol. They are distributed throughout the CNS and PNS and are present in several nonneuronal tissues as well. Phosphorylation of these proteins via cAMP-PK was inhibited markedly by micromolar concentrations of spermine and spermidine. Other particulate-associated peptides phosphorylated via a Ca2+/calmodulin-PK or Ca2+ and cAMP-independent PKs were unaffected by polyamines, whereas the phosphorylation of a 260-kilodalton peptide was markedly enhanced. Spermine did not exert its inhibitory effect indirectly by enhancement of cAMP or ATP hydrolysis or via proteolysis, but its action appears to involve a substrate-directed inhibition of cAMP-PK-promoted phosphorylation as well as enhanced dephosphorylation. Although addition of spermine resulted in marked ribosome aggregation in synaptosomal and microsomal particulate fractions, this phenomenon was not involved in the inhibition of cAMP-PK-promoted phosphorylation.
Two-Step Matrix Application Technique To Improve Ionization Efficiency for Matrix-Assisted Laser Desorption/Ionization in Imaging Mass Spectrometry (2006)

A novel matrix application protocol for direct tissue mass spectrometry is presented. Matrix-assisted laser desorption/ionization is a popular ionization procedure for direct tissue analysis and imaging mass spectrometry. Usually, matrixes are applied by dispensing droplets through either pipettes or automated dispensing machines, or by airbrushing. These techniques are very simple, but it was difficult to obtain uniform matrix crystals on the tissue surface, and nonuniform crystals degrade the spectrum qualities. Here we report a new matrix application protocol, which is a combination of spraying and dispensing droplets, and we have succeeded in overcoming these problems in conventional matrix applications on tissue surfaces. We call our new technique the "spray-droplet method". In this technique, tiny matrix crystals formed by spraying act as seeds for crystal growth. Our technique leads to matrix spots that are filled homogeneously with minute crystals. Such matrix crystals dramatically improve peak intensity and signal-to-noise ratio. In an example on a rat brain section, the number of detectable peaks was increased and signal intensity of m/z 5440 in our method was approximately 30.6 times higher than that in conventional methods. We used this spray-droplet method with a chemical ink-jet technology for matrix deposition to succeed in MALDI imaging of signals, which were undetectable from the conventional matrix applications.
Plan Explanations as Model Reconciliation: Moving Beyond Explanation as Soliloquy (2017)

When AI systems interact with humans in the loop, they are often called on to provide explanations for their plans and behavior. Past work on plan explanations primarily involved the AI system explaining the correctness of its plan and the rationale for its decision in terms of its own model. Such soliloquy is wholly inadequate in most realistic scenarios where the humans have domain and task models that differ significantly from that used by the AI system. We posit that the explanations are best studied in light of these differing models. In particular, we show how explanation can be seen as a "model reconciliation problem" (MRP), where the AI system in effect suggests changes to the human's model, so as to make its plan be optimal with respect to that changed human model. We will study the properties of such explanations, present algorithms for automatically computing them, and evaluate the performance of the algorithms.
Interactions of Type IV Collagen and Its Domains with Human Mesangial Cells (1998)

Type IV collagen (COL-IV) interacts with a variety of cell types. We present evidence that human mesangial cells (HMC) bind directly to COL-IV, its major triple helical domain, and the main non-collagenous, NC1 domain. A synthetic peptide, HEP-III, and its triple helical counterpart (THP-III), previously reported to be a heparin-binding domain, also promoted approximately 15% adhesion of HMC. HMC bound to solid-phase-immobilized, intact COL-IV (approximately 75%), isolated NC1 domain (approximately 15%), and a pepsin-derived triple helical fragment,which lacks Hep-III (approximately 65%). We further examined inhibition of HMC adhesion to COL-IV and its domains by using anti-integrin antibodies. Blocking monoclonal antibodies against the alpha2 integrin resulted in 70% inhibition of adhesion to COL-IV and 80% inhibition to HEP-III. Moderate inhibition was observed on the NC1 and triple helical fragments. Anti-alpha1 antibodies inhibited the binding of HMC to COL-IV, the NC1, and triple helical domains, but not to peptide HEP-III. Anti-beta1 antibodies inhibited almost completely (>95%) the adhesion to COL-IV, the NC1, and triple helical fragments; inhibition on HEP-III was approximately 30%. Affinity chromatography studies with solid-phase HEP-III and mesangial cell lysate also demonstrated the presence of integrin alpha2 beta1 along with alpha3 beta1. We conclude that alpha2 beta1 and alpha1 beta1 integrins mediate HMC adhesion to COL-IV. Peptide HEP-III is a major, specific site for alpha2 integrin-mediated binding of mesangial cells to COL-IV. Both the alpha1 beta1 and alpha2 beta1 integrins interact with the NC1 and triple helical fragments of COL-IV. Therefore, we demonstrate that several sites for integrin-mediated interactions exist on several collagenous and non-collagenous domains of COL-IV.
Flow over a circular cylinder with a flexible splitter plate (2023)

In the present work, we study the flow field around, and forces acting on, a circular cylinder with an attached flexible splitter plate/flap. Two cases of flap length ( $L/D$ ), namely, $L/D = 5$ and $L/D = 2$ have been investigated focusing on the effect of variations in flap flexural rigidity, $EI$ . We find that for a range of $EI$ and Reynolds numbers $Re = UD/\nu$ , a non-dimensional bending stiffness $K^{\ast }=EI/((1/2)\rho U^2 L^3)$ collapses flap motion and forces on the system well, as long as $Re>5000$ . In the $L/D = 5$ flap case, two periodic flap deformation regimes in the form of travelling waves are identified (modes I and II), with mode I occurring at $K^{\ast } \approx 1.5\times 10^{-3}$ and mode II at lower $K^{\ast }$ values ( $K^{\ast }<3\times 10^{-5}$ ). In the $L/D = 2$ flap case, we find a richer set of flapping modes (modes A, B, C and D) that are differentiated by their flapping characteristics (symmetric/asymmetric and amplitude). Force measurements show that the largest drag reduction occurs in mode I ( $L/D = 5$ ) and mode C ( $L/D = 2$ ), which also correspond to the lowest lift and wake fluctuations, with the mode C wake fluctuations being lower than even the rigid splitter plate case. In contrast, the highest fluctuating lift, in both $L/D$ cases, occurs at higher $K^{\ast }$ , when the wake frequency is close to the first structural bending mode frequency of the flap. The observed rich range of flap/splitter plate dynamics could be useful for applications such as drag reduction, vibration suppression, reduction of wake fluctuations and energy harvesting.