gebhart/patrepeval huggingface dataset:
Claves para narrar lo fantástico en La puerta entreabierta de Fernanda Kubbs, alter ego de Cristina Fernández Cubas (2019)

espanolEn este trabajo proc uramos indagar las claves de narrar lo fantastico en la novela La puerta entreabierta de Fernanda Kubbs, seudonimo de Cristina Fernandez Cubas. El doble, la metamorfosis, el mundo de la magia, los suenos y los cuentos intercalados son herramientas de las q ue se sirve nuestra autora para reflexionar sobre las fronteras invisibles que separan lo real de lo irreal. Seguiremos de cerca la historia de la joven periodista Isa y el proceso de su metamorfosis a una miniatura, prisionera de una bola de cristal dur ante el periodo de cinco dias. La busqueda de uno mismo, o la parte complementaria del yo, es el hilo que reune los componentes variados de la n ovela . La protagonista que recorre mundos y pasa fronteras hasta recuperar su estado normal nos hace transmitir el horror de vivir la incertidumbre de la cotidianidad. Nos apoyamos en la estrategia de doubling the termino empleado por Ana Rueda, para examinar el juego complicado del doble cuyo objetivo primordial es revelar las preocupaciones metaficcional es de la escritora. E l origen de la escritura, la importancia de la tradicion oral, la rivalidad artistica, el desequilibrio insalvable entre el discurso oral y el escrito son inquietudes artisticas que exigen pasar fronteras y sumergirse en un mundo de li bertad absoluta. EnglishEn this work we try to find out the keys to narrate the fantastic in the novel La puerta entre abierta by Fernanda Kubbs, pseudonym of Cristina Fernandez Cubas. The double, the metamorphosis, the world of magic, dreams and stories interspersed are tools that our author uses to reflect on the invisible borders that separate the real from the unreal. We will closely fol low the story of the young journalist Isa and the process of her metamorphosis into a miniature, imprisoned in a crystal ball during the period of five days . The search for oneself, or the complementary part of the self, is the thread that brings together the various components o f the novel . The protagonist who travels among worlds and passes borders until recover he r no rmal stat e transmit sus the horror of living the uncertainty of everyday life. We rely on the strategy of doubling the a term used b y Ana Rueda, to examine the complicated game of the double whose main objective is to reveal the metafictional concerns of the writer. The origin of writing, the importance of oral tradition, artistic rivalry, the unbridgeable imbalance between oral and wr itten discourse are artistic concerns that require crossing borders and immersing oneself in a world of absolute freedom
Decreased Ratio of CD8+ T Cells to Regulatory T Cells Associated with Decreased Survival in Dogs with Osteosarcoma (2010)

These data support a role for Treg in the immune control of canine OSA and suggest that determination of the CD8/Treg ratio may be useful for assessing outcomes.
Chemoproteomics-Enabled Covalent Ligand Screening Reveals a Thioredoxin-Caspase 3 Interaction Disruptor That Impairs Breast Cancer Pathogenicity (2017)

Covalent ligand discovery is a promising strategy to develop small-molecule effectors against therapeutic targets. Recent studies have shown that dichlorotriazines are promising reactive scaffolds that preferentially react with lysines. Here, we have synthesized a series of dichlorotriazine-based covalent ligands and have screened this library to reveal small molecules that impair triple-negative breast cancer cell survival. Upon identifying a lead hit from this screen KEA1-97, we used activity-based protein profiling (ABPP)-based chemoproteomic platforms to identify that this compound targets lysine 72 of thioredoxin-a site previously shown to be important in protein interactions with caspase 3 to inhibit caspase 3 activity and suppress apoptosis. We show that KEA1-97 disrupts the interaction of thioredoxin with caspase 3, activates caspases, and induces apoptosis without affecting thioredoxin activity. Moreover, KEA1-97 impairs in vivo breast tumor xenograft growth. Our study showcases how the screening of covalent ligands can be coupled with ABPP platforms to identify unique anticancer lead and target pairs.
Calcium antagonists--terminology, classification and comparison. (1985)

A survey is given of the terminology and classification of calcium antagonistic drugs. Calcium entry blockers are defined as drugs of which the major effect is the selective blockade of the slow inward current across the membrane, also under physiological conditions. Calcium overload blockers are defined as compounds which prevent the overloading of the cell with calcium under pathological, ischemic conditions. Both types of drugs should be considered as examples of different principles, although compounds which possess both properties simultaneously are known to exist. Furthermore, a comparison is made between the various groups of calcium entry blockers and calcium overload blockers, with respect to their chemical, pharmacological and therapeutic properties, including their organ specificity.
Effect of evaluation frequency separation on magnetotelluric resolution (2017)

Aiming at the resolution enhancement of the subsurface objects, an evaluation (target) frequency separation criterion is proposed for ma- gnetotelluric (MT) method. The proposed idea is based on the propa- gation geometry of diffused electromagnetic (EM) wave through the earth. Starting from a homogeneous medium and extended it to laye- red earth model, the present study proposed the frequency separation criterion in terms of apparent resistivity and the lowest frequency to be used. To apply the proposed idea in real situation the frequency separa- tion criterion is reduced to a convenient form which is expressed in ter- ms of the lowest frequency only. The effectiveness of the proposed con- dition is examined by applying it to synthetic data. The result shows that the new idea can improve the resolution of the subsurface objects.
Interpenetrating Phase Composites (1992)

An assessment of the processing and properties of interpenetrating phase composites is presented. Such materials, defined as multiphase composites in which each phase is topologically interconnected throughout the micro‐structure, were the subject of a DOE Basic Energy Sciences sponsored workshop on research needs and opportunities held in July 1989 in Snowmass, Colorado. In place of a report representing the proceeding of the workshop, this paper provides a review of the field in its present, nascent state and identifies some of the critical scientific and technological issues posed by development of this class of material. The emphasis is on processing approaches and properties of interpenetrating phase composites. A list of the participants contributing to the workshop is given.
Wetting and Autophobicity of a Polymer Melt on a Network of Itself (1998)

Wetting properties of thin films of a polymer melt on top of a network formed by irradiation cross-linking of an identical melt were studied. The permeability of the network and its wettability as a function of the extent of cross-linking were characterized by nuclear reaction analysis, atomic force microscopy, contact-mechanics measurements of the adhesion energy, and light microscopy. As the degree of cross-linking increased, we observed a crossover from complete to partial wetting, followed by a second crossover back to complete wetting at higher cross-link densities. We suggest that the first crossover is a manifestation of entropy-induced autophobicity arising from the brush-like nature of the cross-linked surface, while the second originates from surface roughening induced by the cross-linking.
Source coding, channel coding and modulation techniques used in the digital spectrum-compatible HDTV system (1991)

The digital spectrum-compatible high-definition television (DSC-HDTV) system, a digital HDTV simulcast system designed for United States terrestrial broadcasting on currently unassignable channels, is described. The system uses progressively scanned source signals and is characterized by an effective, high-performance video compression system. Compression includes motion compensation with hierarchical block matching and block transform coding with adaptive quantization according to perceptual criteria. Video compression is designed to simplify the receiver decoding; only a few VLSI chips and only one full frame memory are required. The source signal, source coding, channel coding, modulation, and performance of the system are discussed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Drug Membrane Interaction and the Importance for Drug Transport, Distribution, Accumulation, Efficacy and Resistance (1994)

Some aspects of drug membrane interaction and its influence on drug transport, accumulation, efficacy and resistance have been discussed. The interactions manifest themselves macroscopically in changes in the physical and thermodynamic properties of "pure membranes" or bilayers. As various amounts of foreign molecules enter the membrane, in particular the main gel to liquid crystalline phase transition can be dramatically changed. This may change permeability, cell-fusion, cell resistance and may also lead to changes in conformation of the embedded receptor proteins. Furthermore, specific interactions with lipids may lead to drug accumulation in membranes and thus to much larger concentrations at the active site than present in the surrounding water phase. The lipid environment may also lead to changes in the preferred conformation of drug molecules. These events are directly related to drug efficacy. The determination of essential molecular criteria for the interaction could be used to design new and more selective therapeutics. This excursion in some aspects of drug membrane interaction underlines the importance of lipids and their interaction with drug molecules for our understanding of drug action, but this is not really a new thought but has been formulated in 1884 by THUDICUM: "Phospholipids are the centre, life and chemical soul of all bioplasm whatsoever, that of plants as well as of animals".
Chronic Ovine Evaluation of a Totally Implantable Electrical Left Ventricular Assist System (1989)

The totally implantable Novacor left ventricular assist system (LVAS) comprises a pump/drive unit (VAD), electronic control and power subsystem (ECP), variable volume compensator (VVC), and belt skin transformer (BST). The system is now undergoing chronic in vivo evaluation. Cumulative animal testing of VAD, VVC, and BST subsystems are 12.1, 4.9, and 43 years, respectively. The longest implants were 279 days for the VAD, 767 days for the VVC, and 1,148 days for the BST. A chronic implant of the total system was electively terminated at 260 days. The LVAS was powered via the BST. Continuously monitored hemodynamic and pump parameters have demonstrated normal hemodynamics and LVAS operation. Periodic VVC determinations suggest a 0.8 ml/day diffusive gas loss. Tether-free operation has been demonstrated with an Ag-Zn battery backpack. The animal was healthy and free of infection as indicated by routine hematologic, biochemical and serum enzyme determinations. Hemolysis is minimal (plasma free hemoglobin <5 mg%). Pump output ranged from 7 to 8 L/min. Severe valve calcification was the reason for elective termination at 260 days. This preclinical in vivo experience, and in vitro reliability studies, demonstrate efficacy of the total system.
Epigenetic modifier-induced biosynthesis of novel fusaric acid derivatives in endophytic fungi from Datura stramonium L. (2013)

The treatment of fungi with DNA methyltransferase (DNMT) and/or histone deacetylase (HDAC) inhibitors is a promising way to activate secondary metabolite biosynthetic pathways that are dormant under normal conditions. In this study, we included an HDAC inhibitor, suberoylanilide hydroxamic acid (SBHA), in the culture medium of endophytic fungi isolated from the medicinal plant Datura stramonium L. The production of two compounds was induced in the culture supplemented with SBHA, and their structures were determined to be the fusaric acid derivatives 5-butyl-6-oxo-1,6-dihydropyridine-2-carboxylic acid and 5-(but-9-enyl)-6-oxo-1,6-dihydropyridine-2-carboxylic acid. The result confirmed that the use of chemical epigenetic modifiers is an effective technique for promoting the expression of silent biosynthetic pathways to produce unique secondary metabolites.
Novel Strategy for Synthesis of Substituted Benzimidazo[1,2-<i>a</i>]quinolines (2013)

An efficient method for the synthesis of benzimidazo[1,2-a]quinolines under transition-metal-free conditions has been developed through a cascade reaction involving sequential aromatic nucleophilic substitution and intramolecular Knoevenagel condensation reactions. This method is applicable for the synthesis of a wide range of benzimidazo[1,2-a]quinoline derivatives from readily available 2-fluoroarylaldehyde and benzimidazole substrates.
Annealing and Recrystallization of Single Crystals of Polyethylene on Graphite: An Atomic Force Microscopy Study (2006)

In situ and ex‐situ atomic force microscopy (AFM) studies of annealing of solution‐grown single crystals of polyethylene (PE) on graphite were performed at temperatures up to 170°C. Structural changes of the crystals began at ∼90°C at the interface between the lamellar crystal and the substrate where solvent traces are likely trapped after crystal collapse. Initially, material at the edges and in a few central locations of the lozenge‐shaped crystals was converted into 20 nm wide and 3 nm thick strands. As annealing temperature increases, this transformation spreads over the whole crystal, and at 110°C the arrays of the strands, which were oriented differently in the different crystal sectors, completely filled the lozenge frame. The final morphology, which reflects the recrystallization and most likely the reorientation of the PE chains from the vertical to the horizontal direction with respect to the substrate, does not depend on the sample drying prior to the annealing experiments. Annealing of the recrystallized PE samples led to flattening and widening of the strands, which transformed into stacks of molecular ribbons. Some of the ribbons extended from the lozenge shape to the substrate and their orientation results from epitaxy on the graphite. After melting of the polymer structures above 140°C, ordered molecular ribbons of partially extended polymer chains were detected at the melt‐substrate interface at temperatures up to 170°C.
A low power CMOS temperature sensor frontend for RFID tags (2018)

A CMOS temperature sensor fronted with a dual slope analog to digital converter (DSADC) for thermal monitoring is implemented in GlobalFoundries' 45 nm CMOS SOI technology. The sensor has 8 transistors to minimize chip area and its supply voltage can be scaled down to 0.6V to reduce the power consumption by 70%. The ADC is also optimized for small area with a measured resolution of 8 bits and a sampling rate of 30 kS/s. The whole fronted including the amplifier and analog multiplexer consumes on 34 μW under a 1V supply with measured temperature range from 20°C to 100°C and +0.7/-1°C error.
Android malware classification method (2013)

The number of Android malware is increasing with the growth of Android, so there needs to have a method to classify malware families. There are many classification methods proposed so far, but most of them are based on permission information such as the number of requested permissions and critical permissions. Since permission information cannot represent actual application behaviors and permissions are easily separated into several communicating applications, the permission based classification methods can result in false alarms. Opposed to these permission based methods, our classification method is based on applications' Bytecode that contains actual application behaviors. Each malicious application family may have some similar Bytecode and can be classified using this information. In this paper, we propose a method to classify malware families from known malware, as a pre-step of malware detection.
Control of the <i>SOST</i> Bone Enhancer by PTH Using MEF2 Transcription Factors (2007)

These data strongly suggest that SOST expression in osteocytes of adult bone and its inhibition by PTH is mediated by MEF2A, C, and D transcription factors controlling the SOST bone enhancer. Hence, MEF2s are implicated in the regulation of adult bone mass.
The Wrist: Diagnosis and Operative Treatment (1998)

VOLUME ONE--Background. Carpal Comprehension: A Short Look at a History of Understanding the Wrist Joint. Anthropology and Comparative Anatomy. Anatomy. General Anatomy. Bones and Joints. Ligament Anatomy. Vascular and Neurologic Anatomy. Surgical Approaches. Arthrotomy. Arthroscopic Anatomy of the Wrist. Pathomechanics of Wrist Injuries. Force Transmission Through Radiocarpal Joint. Kinematics of the Radiocarpal Joint. Mechanics of the Distal Radioulnar Joint. Examination of the Wrist. Physical Examination of the Wrist. Imaging of the Wrist. Wrist Arthroscopy. Fractures of the Wrist. Fractures of the Distal Radius. Malunion of the Distal Radius. Scaphoid Fractures and Nonunion. Lunate Fractures: Kienbock's Disease. Isolated Carpal Fractures. Carpal Instability. Classification of Carpal Instability. Scapholunate Instability. Lunotriquetral Sprains. Carpal Instability Nondissociative. Radiocarpal Instability and Radiocarpal Dislocations. Post-Traumatic Arthritis of the Wrist. Dislocations and Fractures. Perilunate Dislocations. Perilunate Fracture Dislocations. Axial Dislocations and Fracture Dislocations. Isolated Carpal Dislocations. VOLUME TWO--Injuries of Distal Radioulnar Joint. Tears of the Triangular Fibrocartilage of the Wrist. Fractures of the Distal Radioulnar Joint. Dorsal and Palmar Dislocations of the Distal Radioulnar Joint. Ulnocarpal Abutment. Arthritis Deformity: Resection Arthroplasty and Fusion. Disorders of the Distal Radioulnar Joint. Rheumatoid Arthritis. Clinical Evaluation of the Arthritic Wrist. Soft-Tissue Reconstruction. Wrist Fusion: Partial and Complete. Total Wrist Arthroplasty. Variant Forms of Arthritis: Juvenile Rheumatoid Arthritis, Systemic Lupus Erythematosus, And Psoriatic Arthritis. Developmental Disorders. Madelung's Deformity. Growth-Plate Injuries. Deformities and Problems of the Wrist in Children with Multiple Hereditary Osteochondromata. The Child's Wrist: Diagnostic and Treatment Problems. Athletic Injuries of the Wrist. Complications of Wrist Injuries and Treatment. Complications of Injuries of the Wrist (And Chronic Pain Management). Compartment Syndromes and Ischemic Contracture: Hand, Wrist, And Forearm. Synovitis of the Wrist. Soft-Tissue Problems and Neoplasms. Ganglions of the Wrist. Tendinitis of the Wrist. Carpal Tunnel Syndrome. Tumors of the Wrist. Rehabilitation of the Wrist. Physical Therapy Modalities. Wrist Rehabilitation and Splinting: Occupational Therapy. Work Rehabilitation. Overuse Syndrome. The Future. Anticipations and Needs.
ELECTROMAGNETIC OPTIMAL DESIGN AND PREPARATION OF BROADBAND CERAMIC RADOME MATERIAL WITH GRADED POROUS STRUCTURE (2010)

Silicon nitride (Si 3 N 4 ) ceramic is a promising ultra-high speed (> 5 mach) broadband (1-18 GHz) radome material because of its excellent high-temperature resistance, good mechanical and dielectric properties. Si 3 N 4 ceramics with A-sandwich wall structure are successfully applied to passive self-direction high transmission efficiency broadband radome (1-18 GHz). In the present study, a novel graded porous wall structure for broadband radome is promoted. The feasibility of using this structure is carried out by a computer aided design for the wall structure based on the microwave equivalent network method. By optimizing the layer number (n), structural coefficient (p), thickness (d) and dielectric constant () of each layer, the power transmission efficiency at 1-18 GHz of graded porous Si 3 N 4 ceramic radome is calculated. Si 3 N 4 ceramics with graded porous structure are then prepared according to the design. The prepared sample exhibits a good graded porous structure with the porosity range from 2% to 63 %. The tested power transmission efficiency at 1-18 GHz for the obtained sample matches well with the calculation results, indicating that the graded porous structure is feasible for the broadband radome application.
Principles of albumin and IgG analyses in neurological disorders. III. Evaluation of IgG synthesis within the central nervous system in multiple sclerosis (1977)

Fifty-nine multiple sclerosis patients were investigated with regard to blood-brain barrier function by determining the CSF-protein and the CSF/S albumin ratio. Abnormal values were found in 19% and 32% respectively. The occurrence of CSF-IgG elevation due to synthesis within the CNS was analysed by determining the CSF IgG/protein and CSF IgG/albumin ratios and the IgG-index = (CSF/S IgG ratio)/(CSF/S albumin ratio). Increased values were found in 75%, 80% and 86%, respectively. Oligoclonal IgG was found in CSF by agarose gel electrophoresis in 88% of the patients. The IgG-index is the parameter recommended for the demonstration of an IgG elevation in CSF due to synthesis within the CNS.
On-line visualization of underground structures using context features (2010)

We introduce an on-line framework for the visualizing of underground structures that improves X-Ray vision and Focus and Context Rendering for Augmented Reality. Our approach does not require an accurate reconstruction of the 3D environment and runs on-line on modern hardwares. For these purposes, we extract characteristic features from video frames and create visual cues to reveal occlusion relationships. To enhance the perception of occluding order, the extracted features are either directly rendered, or used to create hybrid blending masks: we thus ensures that the resulting cues are clearly noticeable.
Comparative Assessment of Various Machine Learning‐Based Bias Correction Methods for Numerical Weather Prediction Model Forecasts of Extreme Air Temperatures in Urban Areas (2020)

Abstract Forecasts of maximum and minimum air temperatures are essential to mitigate the damage of extreme weather events such as heat waves and tropical nights. The Numerical Weather Prediction (NWP) model has been widely used for forecasting air temperature, but generally it has a systematic bias due to its coarse grid resolution and lack of parametrizations. This study used random forest (RF), support vector regression (SVR), artificial neural network (ANN) and a multi‐model ensemble (MME) to correct the Local Data Assimilation and Prediction System (LDAPS; a local NWP model over Korea) model outputs of next‐day maximum and minimum air temperatures ( and ) in Seoul, South Korea. A total of 14 LDAPS model forecast data, the daily maximum and minimum air temperatures of in‐situ observations, and five auxiliary data were used as input variables. The results showed that the LDAPS model had an R 2 of 0.69, a bias of −0.85 °C and an RMSE of 2.08 °C for forecast, whereas the proposed models resulted in the improvement with R 2 from 0.75 to 0.78, bias from −0.16 to −0.07 °C and RMSE from 1.55 to 1.66 °C by hindcast validation. For forecasting , the LDAPS model had an R 2 of 0.77, a bias of 0.51 °C and an RMSE of 1.43 °C by hindcast, while the bias correction models showed R 2 values ranging from 0.86 to 0.87, biases from −0.03 to 0.03 °C, and RMSEs from 0.98 to 1.02 °C. The MME model had better generalization performance than the three single machine learning models by hindcast validation and leave‐one‐station‐out cross‐validation.