gebhart/patrepeval huggingface dataset:
Nonuniformity two-point linear correction errors in infrared focal plane arrays (1998)

The error and hence the residual nonuniformity in an IR focal plane array, after two-point linear nonuniformity correction, which results from measurement errors and nonlinearity, is calculated, yielding different results than have been obtained in the past.
Shedding of G<sub>D2</sub> ganglioside by human neuroblastoma (1987)

Substantial concentrations of the cell-surface glycosphingolipid, the disialoganglioside GD2, are uniformly present in human neuroblastoma tumors. This ganglioside can also be detected in the plasma of patients with neuroblastoma by direct thin-layer chromatographic analysis. Among 32 neuroblastoma patients in all clinical stages studied prior to the initiation of treatment, 27 (84%) showed measurably elevated plasma concentrations of GD2 (greater than or equal to 50 pmol/ml). The mean level (545 +/- 108 pmol/ml) was more than 50 times the normal plasma GD2 concentration of less than or equal to 10 pmol/ml. Circulating GD2 was not detected in the plasma of patients with the related, more differentiated tumors, ganglioneuroblastoma and ganglioneuroma, indicating an association of the shedding of this ganglioside with the undifferentiated phenotype. Circulating GD2 diminished in patients in response to therapy, and reappeared in patients whose disease recurred. The results suggest that the sequential determination of circulating GD2 will be of value in monitoring individual patients with neuroblastoma.
Approximate diffraction modeling for real-time sound propagation simulation (2020)

Convincing simulation of diffraction around obstacles is critical in modeling sound propagation in virtual environments. Due to the computational complexity of large-scale wavefield simulations, ray-based models of diffraction are used in real-time interactive multimedia applications. Among popular diffraction models, the Biot-Tolstoy-Medwin (BTM) edge diffraction model is the most accurate, but it suffers from high computational complexity and hence is difficult to apply in real time. This paper introduces an alternative ray-based approach to approximating diffraction, called Volumetric Diffraction and Transmission (VDaT). VDaT is a volumetric diffraction model, meaning it performs spatial sampling of paths along which sound can traverse the scene around obstacles. VDaT uses the spatial sampling results to estimate the BTM edge-diffraction amplitude response and path length, with a much lower computational cost than computing BTM directly. On average, VDaT matches BTM results within 1-3 dB over a wide range of size scales and frequencies in basic cases, and VDaT can handle small objects and gaps better than comparable state-of-the-art real-time diffraction implementations. A GPU-parallelized implementation of VDaT is shown to be capable of simulating diffraction on thousands of direct and specular reflection path segments in small-to-medium-size scenes, within strict real-time constraints and without any precomputed scene information.
The emergence and characterization of macrophage-tropic SIV/HIV chimeric viruses (SHIVs) present in CD4+ T cell-depleted rhesus monkeys (2003)

Highly pathogenic simian immunodeficiency virus/human immunodeficiency virus type 1 chimeric viruses (SHIVs) induce an extremely rapid, systemic, and irreversible depletion of CD4+ T lymphocytes following their inoculation into rhesus macaques. Confocal fluorescence microscopy was used to demonstrate that high levels of viremia in infected animals were sustained by virus-producing tissue macrophage (mphi) following the irreversible elimination of CD4+ T lymphocytes by highly pathogenic SHIVDH12R. The envelope glycoproteins carried by plasma virus in CD4-depleted animals were found to contain specific alterations affecting the V2 region of gp120; similar V2 changes were observed during independent monkey infections. The altered V2 loops contained double amino acid deletions and the loss of a highly conserved N-linked glycosylation site. In contrast to the starting highly pathogenic SHIV, which is exclusively T cell-tropic, some mphi-phase SHIVs, bearing altered V2 regions, were able to establish spreading infections of cultured alveolar mphi.
JPEG compression history estimation for color images (2004)

We routinely encounter digital color images that were previously JPEG-compressed. We aim to retrieve the various settings - termed JPEG compression history (CH) - employed during previous JPEG operations. This information is often discarded en-route to the image's current representation. The discrete cosine transform coefficient histograms of previously JPEG-compressed images exhibit near-periodic behavior due to quantization. We propose a statistical approach to exploit this structure and thereby estimate the image's CH. Using simulations, we first demonstrate the accuracy of our estimation. Further, we show that JPEG recompression performed by exploiting the estimated CH strikes an excellent file-size versus distortion tradeoff.
Combined Angiogenic and Osteogenic Factor Delivery Enhances Bone Marrow Stromal Cell-Driven Bone Regeneration (2005)

Concerted delivery of BMP-4, VEGF, and hBMSCs promoted greater bone formation relative to any single factor or combination of two factors. Materials systems that allows multifactorial presentation more closely mimic natural developmental processes, and these results may have important implications for bone regeneration therapeutics.
Lateral wedge insoles for medial knee osteoarthritis: 12 month randomised controlled trial (2011)

Lateral wedge insoles worn for 12 months provided no symptomatic or structural benefits compared with flat control insoles. Trial registration Australian New Zealand Clinical Trials Registry ACTR12605000503628 and ClinicalTrials.gov NCT00415259.
An Adaptive IR-HARQ Scheme for Polar Codes by Polarizing Matrix Extension (2018)

In this letter, we construct rate compatible polar codes via polarizing matrix extension, to support efficient adaptive incremental redundancy hybrid automatic repeat request (IR-HARQ) protocol. We show that an arbitrary number of incremental coded bits can be generated by extending the polarizing matrix, such that multiple retransmissions are aggregated to produce a longer polar code with extra coding gain. This coding gain is maximized by selecting the most reliable bit channels in the extended codes, rather than the shorter codes, as information bits. Naturally, some information bits are transferred from the shorter part to the extended part for higher bit channel reliability. One-to-one parity-checking between the two parts lends itself well to the above purpose during the construction of the longer code. Simulation results demonstrate consistent coding gain over the chase combining HARQ scheme.
Minimally Invasive Treatments of Osteoporotic Vertebral Compression Fractures (2003)

Vertebroplasty and kyphoplasty are currently used to treat osteoporotic VCFs with successful short-term results. Prospective, randomized studies comparing these procedures to one another and comparing their long-term outcomes to conventional medical management are required to define precise roles of these exciting treatments in the spine physician's armamentarium.
Thermally controlled alignment for wafer-scale lithography (2013)

A primary limitation in nanoimprint lithography is lack of alignment consistency between multiple fields. Simultaneous imprinting of several fields is highly desirable for enhanced throughput, yet placement errors in template fabrication and other factors limit field-to-field accuracy. Here, we describe a method to improve overlay simultaneously across many fields via continuous, in situ control of localized temperature distributions. In this method, interferometric moiré alignment signals from an array of microscopes are analyzed to form a map of distortion and control the distribution of heat in real time. Thermal cross-talk between fields is minimized using a microchannel wafer chuck. We demonstrate simultaneous operation of feedback loops that stabilize alignment over a 100-mm span to 0.5 nm (3σ ).
PCR mediated analysis of RNA sequences (1993)

Journal Article PCR mediated analysis of RNA sequences Get access Martin Hetzer, Martin Hetzer Vienna Biocenter, Institute for Microbiology and GeneticsA-1030 Vienna, Austria Search for other works by this author on: Oxford Academic PubMed Google Scholar Manfred W. Mueller Manfred W. Mueller * Vienna Biocenter, Institute for Microbiology and GeneticsA-1030 Vienna, Austria *To whom correspondence should be addressed Search for other works by this author on: Oxford Academic PubMed Google Scholar Nucleic Acids Research, Volume 21, Issue 23, 25 November 1993, Pages 5526–5527, https://doi.org/10.1093/nar/21.23.5526 Published: 25 November 1993 Article history Received: 08 September 1993 Revision received: 21 October 1993 Accepted: 21 October 1993 Published: 25 November 1993
Practical Performance Degradation Mitigation Solution Using Anomaly Detection for Carrier-Grade Software Networks (2018)

One of the critical technologies required for the large scale acceptance of network functions virtualization within carrier-grade communication systems is the maintenance of a predictable performance level for the software network functions. However, due to the specific resource allocation and to the implementation of the software itself, the performance of the network functions tends to degrade in time, thus, reducing the capacity of the system to serve the specific service requirements. This article introduces a practical solution for performance degradation detection and mitigation for telecom oriented software networks. Also. It includes the mechanisms to interact with the software network and a mechanism for abnormal behaviour detection, as basis for the performance degradation automatic decisions. Furthermore, the solution is exemplified as an addition to the current 5G core network architecture and evaluated on a testbed based on the Fraunhofer FOKUS Open5GCore toolkit and IBM DeepAD. The measured results show that such a solution is feasible and should be further investigated to be integrated in the next generation carrier-grade software networks management for enabling an autonomous long duration functioning of the network.
Portunes+: Privacy-Preserving Fast Authentication for Dynamic Electric Vehicle Charging (2016)

Dynamic contactless charging is an emerging technology for charging electric vehicles (EVs) on the move. For efficient charging and for proper billing, dynamic charging requires secure communication between the charging infrastructure and the EVs that supports very frequent real-time message exchange for EV authentication. In this paper, we propose Portunes+, an authentication protocol for charging pads to authenticate an EVs identity. Portunes+ uses pseudonyms to provide location privacy, allows EVs to roam between different charging sections and receive a single bill, and achieves fast authentication by relying on symmetric keys and on the spatiotemporal location of the EV. We have implemented Portunes+ on RaspberryPi 2 Model B with 900 MHz CPU and 1 GB RAM. Portunes+ allows the EV to generate authentication information within 0.15 ms and allows charging pads to verify the information within 0.11 ms. In comparison, Elliptic Curve Digital Signature Algorithm signature generation and verification take over 9 ms and over 14 ms, respectively.
3′-Phosphodiesterase and 3′→5′ Exonuclease Activities of Yeast Apn2 Protein and Requirement of These Activities for Repair of Oxidative DNA Damage (2001)

In Saccharomyces cerevisiae, the AP endonucleases encoded by the APN1 and APN2 genes provide alternate pathways for the removal of abasic sites. Oxidative DNA-damaging agents, such as H(2)O(2), produce DNA strand breaks which contain 3'-phosphate or 3'-phosphoglycolate termini. Such 3' termini are inhibitory to synthesis by DNA polymerases. Here, we show that purified yeast Apn2 protein contains 3'-phosphodiesterase and 3'-->5' exonuclease activities, and mutation of the active-site residue Glu59 to Ala in Apn2 inactivates both these activities. Consistent with these biochemical observations, genetic studies indicate the involvement of APN2 in the repair of H(2)O(2)-induced DNA damage in a pathway alternate to APN1, and the Ala59 mutation inactivates this function of Apn2. From these results, we conclude that the ability of Apn2 to remove 3'-end groups from DNA is paramount for the repair of strand breaks arising from the reaction of DNA with reactive oxygen species.
Zonisamide improves wearing‐off in Parkinson's disease: A randomized, double‐blind study (2015)

The study provides evidence that confirms the efficacy of zonisamide 50 mg/d for reduction in "off" time in PD patients with wearing-off phenomena.
Few Mutations Divide Some Drug-Resistant TB Strains (2007)

TUBERCULOSISThe first genome analysis of an extensively drug-resistant tuberculosis strain has found that only a small number of mutations distinguish it from a less drug-resistant strain and a drug-sensitive one.
The Design and Implementation of Scenario Demonstration Software System for Intelligent Satellite Artificial System (2018)

This paper applies the theory of parallel systems to construct the scenario demonstration software framework of intelligent satellite(iSat) artificial system, and designs a scenario demonstration software system of intelligent satellite artificial system by using Eclipse platform with its integration functions. First of all, the system is designed and integrated with the control and display functions of each module of the artificial system. After that, the Satellite Tool Kit (STK) is redeveloped and embedded into the Eclipse platform, which enables the STK scenario simulation and analysis functions to be invoked. On this basis, the exchange of the internal information of the software is designed, and the interaction from the configuration file to the hardware platform and the STK scenario presentation module is realized. Finally, combined with the demonstration of a single multifunctional satellite scenario and multiple satellite networking scenarios, this paper verifies the simulation function of the intelligent satellite artificial scenario demonstration software.
Leptin as a Uremic Toxin Interferes with Neutrophil Chemotaxis (2004)

Leptin is a pleiotropic molecule involved in energy homeostasis, hematopoiesis, inflammation, and immunity. Hypoleptinemia characterizing starvation has been strictly related to increased susceptibility to infection secondary to malnutrition. Nevertheless, ESRD is characterized by high susceptibility to bacterial infection despite hyperleptinemia. Defects in neutrophils play a crucial role in the infectious morbidity, and several uremic toxins that are capable of depressing neutrophil functions have been identified. Only a few and contrasting reports about leptin and neutrophils are available. This study provides evidence that leptin inhibits neutrophil migration in response to classical chemoattractants. Moreover, serum from patients with ESRD inhibits migration of normal neutrophils in response to N-formyl-methionyl-leucyl-phenylalanine with a strict correlation between serum leptin levels and serum ability to suppress neutrophil locomotion. Finally, the serum inhibitory activity can be effectively prevented by immune depletion of leptin. The results also show, however, that leptin by itself is endowed with chemotactic activity toward neutrophils. The two activities-inhibition of the cell response to chemokines and stimulation of neutrophil migration-could be detected at similar concentrations. On the contrary, neutrophils exposed to leptin did not display detectable [Ca(2+)](i) mobilization, oxidant production, or beta(2)-integrin upregulation. The results demonstrate that leptin is a pure chemoattractant devoid of secretagogue properties that are capable of inhibiting neutrophil chemotaxis to classical neutrophilic chemoattractants. Taking into account the crucial role of neutrophils in host defense, the leptin-mediated ability of ERSD serum to inhibit neutrophil chemotaxis appears as a potential mechanism that contributes to the establishment of infections in ERSD.
Reviews (1982)

Reviews Get access The Subordination of Teaching to Learning A seminar conducted by Caleb GattegnoBristol 6th–8th November 1981 Roger Scott, Roger Scott Euorcentre, Bournemouth Search for other works by this author on: Oxford Academic Google Scholar Mary Page Mary Page Euorcentre, Bournemouth Search for other works by this author on: Oxford Academic Google Scholar ELT Journal, Volume 36, Issue 4, July 1982, Page 273, https://doi.org/10.1093/elt/36.4.273 Published: 01 July 1982 Article history Received: 01 December 1981 Published: 01 July 1982
Giant saltation on Mars (2008)

Saltation, the motion of sand grains in a sequence of ballistic trajectories close to the ground, is a major factor for surface erosion, dune formation, and triggering of dust storms on Mars. Although this mode of sand transport has been matter of research for decades through both simulations and wind tunnel experiments under Earth and Mars conditions, it has not been possible to provide accurate measurements of particle trajectories in fully developed turbulent flow. Here we calculate the motion of saltating grains by directly solving the turbulent wind field and its interaction with the particles. Our calculations show that the minimal wind velocity required to sustain saltation on Mars may be surprisingly lower than the aerodynamic minimal threshold measurable in wind tunnels. Indeed, Mars grains saltate in 100 times higher and longer trajectories and reach 5-10 times higher velocities than Earth grains do. On the basis of our results, we arrive at general expressions that can be applied to calculate the length and height of saltation trajectories and the flux of grains in saltation under various physical conditions, when the wind velocity is close to the minimal threshold for saltation.
Marine CSEM signal propagation in TIV media (2007)

In marine CSEM and SBL the seabed subsurface is explored by emitting low‐frequency signals from an electric dipole source which is towed close to the seabed. The main goal is to detect and characterize possible thin resistive layers within the conductive surroundings beneath the seabed. Investigations of how the response from a resistive reservoir varies with characteristic parameters such as layer thickness and conductivity can be made using standard numerical modeling tools. However, the response from a thin resistive layer can be described by explicit spatial expressions that are derived by analyzing the CSEM field integrals with asymptotic methods. To gain understanding and physical insight into how CSEM signals propagate, it is informative to obtain and analyze such spatial expressions. I here present spatial expressions for the electromagnetic field responses from a thin resistive layer in transversely isotropic media, and furthermore discuss how the analytic expressions can be used in interpretation of marine CSEM field data.
Modeling magnetic core loss for sinusoidal waveforms (2008)

Among the challenging unsolved technical problems that have plagued the minds of scientist and engineers throughout the 20th and 21st century is the development of a quantifiable model to accurately estimate or explain Core Power Losses (CPL). Theoretical advances in magnets led to many model proposals, but as these models were experimentally examined, they quickly lost their validation. Many of the current models use manufacturer's material estimates to form limited curve fitted equations. These equations are only valid for a specific waveform over a specified range. Unless the designers use the same conditions used to determine the manufacturer's fitted equations, the models quickly lose their precision. The scope of this thesis is to explain and compare several of the current models and evaluate them using experimental data. The validity of some of the term components used in many of these models will also be investigated.
iRHOM2 takes control of rheumatoid arthritis (2013)

The cytokine TNF-α is a major drug target for rheumatoid arthritis, an inflammatory joint disorder. An alternative approach is to target the protease TNF-α convertase (TACE), which releases TNF-α from cells. However, because TACE cleaves other proteins involved in development and cancer, a tissue-specific inhibition of TACE in immune cells appears mandatory. In this issue of the JCI, Issuree et al. report that iRHOM2 is a TACE activator in immune cells. Loss of iRHOM2 largely protects mice from inflammatory arthritis, making iRHOM2 a potential drug target for this condition.
Test generation systems in Japan (1975)

With the advent of large scale and medium scale integrated circuit, test and diagnosis of digital logic circuits become more and more difficult to get an efficient and economical goal.In this paper, Test Generation Systems for testing digital logic circuits (IC Cards) in Japan are introduced. One implemented in Nippon Electric Co. is described in detail. Future problems of Test Generation Systems are also briefly discussed.
Mechanisms of tissue injury with reference to rheumatoid arthritis (1975)

Mechanisms of tissue injury with reference to rheumatoid arthritis , Mechanisms of tissue injury with reference to rheumatoid arthritis , مرکز فناوری اطلاعات و اطلاع رسانی کشاورزی
Power supply transient signal integration circuit (2002)

We discuss a circuit which measures and analyses power supply transients as defined in the test technique, Transient Signal Analysis (TSA). This circuit can replace the benchtop instrumentation and offline signal processing software used in previous work. The circuit accepts voltage transients as analog inputs from the Device-Under-Test (DUT), performs integration and outputs an analog value to the tester. The tester compares the output value to a predetermined threshold as a means of determining the pass/fail status of the DUT. This circuit is designed to simplify the hardware requirements of TSA.
PanDrugs: a novel method to prioritize anticancer drug treatments according to individual genomic data (2018)

PanDrugs is a feasible method to identify potentially druggable molecular alterations and prioritize drugs to facilitate the interpretation of genomic landscape and clinical decision-making in cancer patients. Our approach expands the search of druggable genomic alterations from the concept of cancer driver genes to the druggable pathway context extending anticancer therapeutic options beyond already known cancer genes. The methodology is public and easily integratable with custom pipelines through its programmatic API or its docker image. The PanDrugs webtool is freely accessible at http://www.pandrugs.org .
Neural correlates of frustration (2005)

Psychological considerations suggest that the omission of rewards in humans comprises two effects: first, an allocentric effect triggering learning and behavioural changes potentially processed by dopaminergic neurons according to the prediction error theory; second, an egocentric effect representing the individual's emotional reaction, commonly called frustration. We investigated this second effect in the context of omission of monetary reward with functional magnetic resonance imaging. As expected, the contrast omission relative to receipt of reward led to a decrease in ventral striatal activation consistent with prediction error theory. Increased activation for this contrast was found in areas previously related to emotional pain: the right anterior insula and the right ventral prefrontal cortex. We interpreted this as a neural correlate of the egocentric effect.