gebhart/patrepeval huggingface dataset:
Molecular cloning of cDNAs encoding the protein backbones of arabinogalactan‐proteins from the filtrate of suspension‐cultured cells of <i>Pyrus communis</i> and <i>Nicotiana alata</i> (1995)

This paper reports the isolation of cDNAs encoding the protein backbone of two arabinogalactan-proteins (AGPs), one from pear cell suspension cultures (AGPPc2) and the other from suspension cultures of Nicotiana alata (AGPNa2). The proteins encoded by these cDNAs are quite different from the 'classical' AGP backbones described previously for AGPs isolated from pear suspension cultures and extracts of N. alata styles. The cDNA for AGPPc2 encodes a 294 amino acid protein, of which a relatively short stretch (35 amino acids) is Hyp/Pro rich; this stretch is flanked by sequences which are dominated by Asn residues. Asn residues are not a feature of the 'classical' AGP backbones in which Hyp/Pro, Ser, Ala and Thr account for most of the amino acids. The cDNA for AGPNa2 encodes a 437 amino acid protein, which contains two distinct domains: one rich in Hyp/Pro, Ser, Ala, Thr and the other rich in Asn, Tyr and Ser. The composition and sequence of the Pro-rich domain resembles that of the 'classical' AGP backbone. The Asn-rich domains of the two cDNAs described have no sequence similarity; in both cases they are predicted to be processed to give a mature backbone with a composition similar to that of the 'classical' AGPs. The study shows that different AGPs can differ in the amino acid sequence in the protein backbone, as well as the composition and sequence of the arabinogalactan side-chains. It also shows that differential expression of genes encoding AGP protein backbones, as well as differential glycosylation, can contribute to the tissue specificity of AGPs.
Li corrosion resistant glasses for headers in ambient temperature Li batteries (1985)

Glass compositions containing 10 to 50 mol% CaO, 10 to 50 mol% Al/sub 2/O/sub 3/, 30 to 60 mol% B/sub 2/O/sub 3/, and 0 to 30 mol% MgO are provided. These compositions are capable of forming a stable glass-to-metal seal possessing electrical insulating properties for use in a lithium battery. Also provided are lithium cells containing a stainless steel body and molybdenum center pin electrically insulated by means of a seal produced according to the invention.
Design, Processing, Microstructure, Properties, and Applications of Advanced Intermetallic TiAl Alloys (2012)

Abstract After almost three decades of intensive fundamental research and development activities, intermetallic titanium aluminides based on the ordered γ‐TiAl phase have found applications in automotive and aircraft engine industry. The advantages of this class of innovative high‐temperature materials are their low density and their good strength and creep properties up to 750 °C as well as their good oxidation and burn resistance. Advanced TiAl alloys are complex multi‐phase alloys which can be processed by ingot or powder metallurgy as well as precision casting methods. Each process leads to specific microstructures which can be altered and optimized by thermo‐mechanical processing and/or subsequent heat treatments. The background of these heat treatments is at least twofold, i.e., concurrent increase of ductility at room temperature and creep strength at elevated temperature. This review gives a general survey of engineering γ‐TiAl based alloys, but concentrates on β‐solidifying γ‐TiAl based alloys which show excellent hot‐workability and balanced mechanical properties when subjected to adapted heat treatments. The content of this paper comprises alloy design strategies, progress in processing, evolution of microstructure, mechanical properties as well as application‐oriented aspects, but also shows how sophisticated ex situ and in situ methods can be employed to establish phase diagrams and to investigate the evolution of the micro‐ and nanostructure during hot‐working and subsequent heat treatments.
Site‐specific analysis of <i>N</i>‐glycans on haptoglobin in sera of patients with pancreatic cancer: A novel approach for the development of tumor markers (2008)

It was found in our previous studies that the concentration of fucosylated haptoglobin had increased in the sera of patients with pancreatic cancer (PC) compared to those of other types of cancer and normal controls. Haptoglobin, an acute phase protein, has four potential N-glycosylation sites, although it remains unknown which site is responsible for the change in fucosylated N-glycans. In the present study, site-specific N-glycan structures of haptoglobin in sera obtained from patients with PC or chronic pancreatitis (CP) were analyzed using liquid chromatography-electrospray ionization mass spectrometry. Mass spectrometry analyses demonstrated that concentrations of total fucosylated di-, tri- and tetra-branched glycans of haptoglobin increased in the sera of PC patients. Tri-antennary N-glycans containing a Lewis X-type fucose markedly increased at the Asn211 site of haptoglobin N-glycans. While fucosylated N-glycans derived from serum haptoglobin of patients with CP slightly increased, di-fucosylated tetra-antennary N-glycans were observed only at this site in PC patients, and were absent in the haptoglobin of normal controls and individuals with CP. Thus, the present study provides evidence that site-specific analyses of N-glycans may be useful as novel tumor markers for PC.
End-to-End Learning of Compressible Features (2020)

Pre-trained convolutional neural networks (CNNs) are powerful off-the-shelf feature generators and have been shown to perform very well on a variety of tasks. Unfortunately, the generated features are high dimensional and expensive to store: potentially hundreds of thousands of floats per example when processing videos. Traditional entropy based lossless compression methods are of little help as they do not yield desired level of compression, while general purpose lossy compression methods based on energy compaction (e.g. PCA followed by quantization and entropy coding) are sub-optimal, as they are not tuned to task specific objective. We propose a learned method that jointly optimizes for compressibility along with the task objective for learning the features. The plug-in nature of our method makes it straight-forward to integrate with any target objective and trade-off against compressibility. We present results on multiple benchmarks and demonstrate that our method produces features that are an order of magnitude more compressible, while having a regularization effect that leads to a consistent improvement in accuracy.
Effect of Cecal Cultures Lyophilized in Skim Milk or Reagent 20 on Salmonella Colonization in Broiler Chicks (1994)

Mixed cultures of cecal bacteria that were grown under continuous flow anaerobic conditions were prepared as lyophilized powder in skim milk or Reagent 20 (R-20; a mixture containing sucrose and bovine serum albumin fraction V) and compared with broth cultures for reduction of Salmonella typhimurium enteric colonization. Day old broiler chicks were provided a standard corn-soybean diet with: 1) no culture, (control); 2) broth culture administered by crop gavage; 3) broth culture added to the drinking water; 4) culture lyophilized in skim milk and added to drinking water; 5) culture lyophilized in skim milk in gelatin capsules and force-fed; 6) culture lyophilized in R-20 and added to drinking water; and 7) culture lyophilized in R-20 in gelatin capsules and force-fed. All groups were challenged on Day 3 with 10(4) cfu of S. typhimurium per chick. Culture by crop gavage, culture in the drinking water, skim milk powder in capsules, and R-20 powder in the water and in capsules significantly (P < .05) reduced mean Salmonella colony-forming units in cecal contents by 3.21 to 5.26 log10 units at 10 d of age. Likewise, the number of cecal-culture-positive chicks in the same groups was significantly less than controls with reductions of 27 to 67%. The numbers of Salmonella per gram of cecal contents and the percentage of cecal-culture-positive chicks in the skim milk powder in the drinking water group were not different from control chicks in one of two experiments.(ABSTRACT TRUNCATED AT 250 WORDS)
Novel Fundamental Model for the Prediction of Multiply Scattered Generic Waves in Particulates (2004)

Fundamental models for accuratetly predicting multiple scattering of electromagnetic and acoustic waves through particulates have been in need for a long time. The lack of these models forces optical size analyzers to only accept highly diluted samples and impairs the performance of acoustic analyzers. After 20 years of R & D this vacuum has been filled with METAMODEL™. This new multiplescattering model is as fundamental as Mie and ECAH single-scattering models. Its generic validity resides in having modeled the interaction between the fields scattered by every particle, leading to generic stochastic field equations where the overlapping of all fields is contemplated regardless of their physical nature (viscous-inertial, thermal diffusion, electromagnetic, elastic, etc.). Its fundamentals are described, and validating data in concentrated dispersions are presented.
Yield and device characteristics of DFB lasers: statistics and novel coating design in theory and experiment (1989)

Uncoated 1.55- mu m InGaAsP distributed-feedback (DFB) lasers show superior properties e.g. smaller linewidth and lower feedback sensitivity, in comparison to devices with low reflective facet(s). However, the phases of both front and rear mirror reflectivities, with respect to the grating, must be within sharp tolerances to get a stable dynamic single longitudinal mode device. These sharp tolerances lead to rather poor yield figures. A type of coating that allows the change of effective mirror phase by an arbitrary angle while preserving the superior high facet reflectivity is presented. To know what coating is optimum when applied to the batchwise process, a thorough statistical investigation in lasing behavior as a function of random facet phases, kL product, and front facet reflectivity is needed. Theoretical predictions of these quantities are presented, and also more general validity. The predictions on optimum phase rotation and the influence of absolute reflectivity values are verified experimentally and are found to very accurate.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A Systematic Comparison of Phrase Table Pruning Techniques (2012)

When trained on very large parallel corpora, the phrase table component of a machine translation system grows to consume vast computational resources. In this paper, we introduce a novel pruning criterion that places phrase table pruning on a sound theoretical foundation. Systematic experiments on four language pairs under various data conditions show that our principled approach is superior to existing ad hoc pruning methods. 1
Castanea sativa (European Chestnut) Leaf Extracts Rich in Ursene and Oleanene Derivatives Block Staphylococcus aureus Virulence and Pathogenesis without Detectable Resistance (2015)

The Mediterranean is home to a rich history of medical traditions that have developed under the influence of diverse cultures over millennia. Today, many such traditions are still alive in the folk medical practices of local people. Investigation of botanical folk medicines used in the treatment of skin and soft tissue infections led us to study Castanea sativa (European Chestnut) for its potential antibacterial activity. Here, we report the quorum sensing inhibitory activity of refined and chemically characterized European Chestnut leaf extracts, rich in oleanene and ursene derivatives (pentacyclic triterpenes), against all Staphylococcus aureus accessory gene regulator (agr) alleles. We present layers of evidence of agr blocking activity (IC50 1.56-25 μg mL-1), as measured in toxin outputs, reporter assays hemolytic activity, cytotoxicity studies, and an in vivo abscess model. We demonstrate the extract's lack of cytotoxicity to human keratinocytes and murine skin, as well as lack of growth inhibitory activity against S. aureus and a panel of skin commensals. Lastly, we demonstrate that serial passaging of the extract does not result in acquisition of resistance to the quorum quenching composition. In conclusion, through disruption of quorum sensing in the absence of growth inhibition, this study provides insight into the role that non-biocide inhibitors of virulence may play in future antibiotic therapies.
Pulsed mid-IR Cr<sup>2+</sup>:ZnS and Cr<sup>2+</sup>:ZnSe lasers pumped by Raman-shifted<i>Q</i>-switched neodymium lasers (2004)

The spectral and lasing properties of Cr2+:ZnS and Cr2+: ZnSe crystals pumped by Raman-shifted nanosecond neodymium lasers are studied. Tunable pulsed lasing is obtained in the mid-IR range between 2.05 and 2.40 μm. The minimum lasing threshold was 170 μJ at the maximum slope efficiency of 20 %.
Process for the combined deasphalting of coal liquids (1984)

A process for the purification of liquefied coal is disclosed, employing a polarity gradient for fractionation. Maltenic and asphaltenic fractions are isolated. Integration of the fractionation process with additional processes such as distillation, partial oxidation, and catalytic hydrotreating is also disclosed.
Uncertainty Quantification of Forecasted Oil Recovery using Dynamic Model Ranking with Application to a ME Carbonate Reservoir (2014)

History matching, being an ill-posed optimization problem, attempts to render multiple realizations of reservoir models that satisfy a given objective function with applicable constraints. A variety of assisted history-matching (AHM) techniques is currently being developed and used with the main objective to generate statistically diverse ensembles of history-matched models to capture the uncertainty in the distribution of reservoir parameters. This paper targets the outstanding questions of how to a) rigorously quantify the uncertainty in the distribution of the most prominent reservoir parameters that govern the reservoir connectivity and b) rank the history-matched models and identify the model candidates for production forecasting without compromising the notion of uncertainty. A workflow has been developed that integrates the modules for AHM and dynamic model ranking (DMR) based on forecasted oil recovery factors (ORFs). A pattern recognition methodology based on a kernel k-means clustering algorithm is used to identify key reservoir models. The reduced set of models is used to minimize the computational load for forecast-based analysis, while retaining the knowledge of the uncertainty in the recovery factor. The comprehensive probabilistic AHM and DMR workflow was implemented at the operator’s North Kuwait Integrated Digital Oilfield (KwIDF) collaboration center. It delivers an optimized reservoir model for waterflood management and automatically updates the model quarterly with geological, production, and completion information.
Epithelial Cell Chirality Revealed by Three-Dimensional Spontaneous Rotation (2018)

Our understanding of the left-right (LR) asymmetry of embryonic development, in particular the contribution of intrinsic handedness of the cell or cell chirality, is limited due to the confounding systematic and environmental factors during morphogenesis and a ack of physiologically relevant in vitro 3D platforms. Here we report an efficient two-layered biomaterial platform for determining the chirality of individual cells, cell aggregates, and self-organized hollow epithelial spheroids. This bioengineered niche provides a uniform defined axis allowing for cells to rotate spontaneously with a directional bias toward either clockwise or counterclockwise directions. Mechanistic studies reveal an actin-dependent, cell-intrinsic property of 3D chirality that can be mediated by actin cross-linking via α-actinin-1. Our findings suggest that the gradient of extracellular matrix is an important biophysicochemical cue influencing cell polarity and chirality. Engineered biomaterial systems can serve as an effective platform for studying developmental asymmetry and screening for environmental factors causing birth defects.
In vivo high speed multispectral fluorescence lifetime imaging (FLIm) of swine coronary arteries (2015)

We report an intravascular catheter system able to acquire multispectral time-resolved fluorescence images of coronary arteries in vivo in swine heart. Current results demonstrate the ability of this system to acquire robust fluorescence lifetime images in pulsatile blood flow.
Effect of Modality on Spelling Words Varying in Linguistic Demands (2006)

The purpose of this study was to determine the extent to which spelling accuracy is influenced by response modality. A spelling list consisting of 40 words that varied in linguistic complexity was administered to students in Grades 2 through 6. Each student completed three tasks: (a) a words-per-minute measure to determine keyboarding proficiency, (b) spelling a word list via handwriting, and (c) spelling a word list on a computer. Independent variables included response modality, linguistic complexity, and grade level. Dependent measures included the percent words spelled correctly. Keyboarding proficiency was included as a covariate. Modality rarely affected spelling accuracy, regardless of the linguistic complexity of the target words. These findings suggest that spelling knowledge draws on modality-free, lexical representations stored in long-term memory. Further, they suggest that computer-based instruments are a viable option for spelling assessment.
Isolation and Characterization of <i>Campylobacter</i> Strains from Diarrheal Patients in Central and Suburban Bangkok, Thailand (2015)

Campylobacter-induced diarrhea is increasingly recognized worldwide. However, little information is available regarding the Campylobacter strains associated with diarrheal patients in Thailand. In this study, we attempted to isolate Campylobacter strains from diarrheal patients in Thailand and to characterize the species using a cytolethal distending toxin (cdt) gene-based C. jejuni, C. coli, and C. fetus-specific multiplex PCR assay. Campylobacter species were also confirmed using 16S rRNA gene sequencing and hipO gene detection. From 2,500 diarrheal stool specimens, 76 Campylobacter-like organisms were isolated and identified via conventional culture methods. Among these 76 organisms, 73 were identified as Campylobacter species (43 C. jejuni, 29 C. coli, and 1 C. fetus) via multiplex PCR, whereas 3 remained unidentified. Two Campylobacter-like organisms yielded 2 amplicons corresponding to cdt genes from C. jejuni and C. coli. Subsequently, C. jejuni and C. coli were reisolated from each sample. The third isolate was identified as C. hyointestinalis via 16S rRNA gene sequencing. To our knowledge, this is the first report on the isolation of C. hyointestinalis from a diarrheal patient in Thailand. These data indicate that C. jejuni (58%) and C. coli (40%) are prevalent among diarrheal patients in Thailand.
Specific Amplification of NADH Using NADH Kinase in a Reaction Mixture Containing Excess NAD (1994)

Journal Article Specific Amplification of NADH Using NADH Kinase in a Reaction Mixture Containing Excess NAD Get access Tsuyoshi Ohno, Tsuyoshi Ohno Noda Institute for Scientific Research, Noda, Chiba 278, Japan To whom correspondence should be addressed. Search for other works by this author on: Oxford Academic Google Scholar Masaru Suzuki, Masaru Suzuki Noda Institute for Scientific Research, Noda, Chiba 278, Japan Present address: Research and Development Division of Kikkoman Corporation, Noda, Chiba 278, Japan. Search for other works by this author on: Oxford Academic Google Scholar Tatsuo Horiuchi Tatsuo Horiuchi Noda Institute for Scientific Research, Noda, Chiba 278, Japan Present address: Research and Development Division of Kikkoman Corporation, Noda, Chiba 278, Japan. Search for other works by this author on: Oxford Academic Google Scholar Bioscience, Biotechnology, and Biochemistry, Volume 58, Issue 5, 1 January 1994, Pages 976–977, https://doi.org/10.1271/bbb.58.976 Published: 01 January 1994 Article history Received: 24 November 1993 Published: 01 January 1994
Optimal sampling and reconstruction of MRI signals resulting from sinusoidal gradients (1991)

The optimum continuous time filter and its various discrete time implementations for free induction delay signals resulting from sinusoidal gradients of magnetic resonance imaging (MRI) are formulated. It is found that the estimation error associated with implementation based on linear temporal sampling, or, equivalently, nonlinear spatial frequency sampling, is smaller than that of nonlinear temporal sampling. It is shown that the optimal maximum likelihood estimator for sinusoidal gradients has higher error variance than that of constant gradients. Experimental results verifying the theoretical predictions are presented.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
P17 INTRAVASCULAR NEUTROPHIL EXTRACELLULAR TRAP (NET) RELEASE PROMOTE VASCULAR INJURY AND TUBULAR NECROSIS UPON ISCHEMIA/REPERFUSION INJURY (IRI) OF KIDNEY (2016)

Acute tubular necrosis (ATN) is common in severe acute kidney injury (AKI). Infiltrating neutrophils contribute to the crescendo of renal inflammation and kidney injury (necroinflammation), but how neutrophils contribute to ATN is not clear. We hypothesized that infiltrating neutrophils release neutrophil extracellular traps (NETs), which implies the release of cytotoxic DAMPs like histones that accelerate ATN and AKI.
NbN/MgO/NbN edge-geometry tunnel junctions (1989)

We report the fabrication and low-frequency testing of the first edge-geometry NbN/MgO/NbN superconducting tunnel junctions. The use of an edge geometry allows very small junction areas to be obtained, while the all-NbN electrodes permit operation at 8–10 K with a potential maximum operating frequency above 1 THz. Edge definition in the base NbN film was accomplished utilizing Ar ion milling with an Al2O3 milling mask, followed by a lower energy ion cleaning step. This process has produced all-refractory-material tunnel junctions with areas as small as 0.1 μm2, resistance-area products less than 21 Ω μm2, and subgap to normal state resistance ratios larger than 18.
Discardable data adaptation in scalable video coding (2007)

This paper proposes two encoding methods for discardable slices in scalable video coding. Discardable slices are not used for inter-layer prediction and can therefore be removed from a coded bitstream from layers below the decoded scalable layer. Consequently, discardable slices need not be transmitted when the layer that the receiver decodes is known by the sender. The potential bit rate saving compared with conventional scalable coding makes the use of discardable slices an attractive encoding strategy, e.g. for unicast streaming applications. Among the two proposed encoding algorithms, one is a two-pass encoding method and the other models the coding problem as a Knapsack Problem (KP). Performed simulations indicate improved rate-distortion performance.