gebhart/patrepeval huggingface dataset:
Cognition in the hearing impaired and deaf as a bridge between signal and dialogue: a framework and a model (2003)

This paper focuses on the role of cognition in visual language processing in the deaf and hard of hearing. Although there are modality-specific cognitive findings in the literature on comparisons across speech communication modes and language (sign and speech), there is an impressive bulk of evidence that supports the notion of general modality-free cognitive functions in speech and sign processing. A working-memory framework is proposed for the cognitive involvement in language understanding (sign and speech). On the basis of multiple sources of behavioural and neuroscience data, four important parameters for language understanding are described in some detail: quality and precision of phonology, long-term memory access speed, degree of explicit processing, and general processing and storage capacity. Their interaction forms an important parameter space, and general predictions and applications can be derived for both spoken and signed language conditions. The model is mathematically formulated at a general level, hypothetical ease-of-language-understanding (ELU) functions are presented, and similarities and differences from current working-memory and speech perception formulations are pointed out.
Phorbol esters modulate insulin receptor phosphorylation and insulin action in cultured hepatoma cells. (1984)

The effect of the tumor-promoting agent phorbol 12-myristate 13-acetate (PMA) on insulin receptors and insulin action was studied in rat hepatoma cells in culture. PMA (0.1-1.0 micrograms/ml) did not affect insulin binding either acutely or chronically but inhibited insulin stimulation of glycogen synthase and tyrosine aminotransferase. PMA (1 microgram/ml) stimulated the phosphorylation of the beta subunit of insulin receptor purified from [32P]phosphate-labeled Fao cells by 1.3-fold in the absence of insulin. In contrast, insulin-stimulated phosphorylation in the presence of PMA was reduced. Phosphoamino acid analysis of the beta subunit after PMA stimulation revealed an increase of both phosphoserine and phosphothreonine residues, whereas insulin stimulated primarily phosphorylation of tyrosine and serine residues. Insulin stimulation of cells after PMA treatment revealed a decrease in phosphotyrosine when compared to cells stimulated by insulin alone. Tryptic peptide mapping of the beta subunit by a two-dimensional chromatographic/electrophoretic separation revealed nine phosphopeptides from the cells treated with PMA. Insulin stimulated phosphorylation at six new sites in the receptor, three of which appeared to be similar to those in PMA-treated cells. This report shows that phorbol esters stimulate insulin receptor phosphorylation, inhibit insulin-induced receptor phosphorylation and insulin action, and suggest a physiologic relation between insulin action and the calcium-activated and phospholipid-dependent protein kinase C.
Trajectory Estimations Using Smartphones (2015)

This paper investigates whether the smartphones' built-in sensors can accurately predict future trajectories for a possible implementation in a vehicle-to-vehicle (V2V) and vehicle-to-infrastructure (V2I) system. If smartphones could be used, vehicles without the V2V/V2I technology could use them to tap into the V2V/V2I infrastructure and help to populate the gap of vehicles off the V2V/V2I grid. To evaluate this, we set up a dead-reckoning system that uses Kalman filters to predict the future trajectory of a vehicle, information that could be used in a V2V/V2I system to warn drivers if the trajectories of vehicles will intersect at the same time. Then, we use a vehicle with accelerometer, GPS, and speedometer sensors mounted on it and evaluate its accuracy in predicting the future trajectory. Afterward, we place a smartphone securely on the vehicle's dashboard, and we use its internal accelerometer and GPS to feed the same dead reckoning and Kalman filter setup to predict the future trajectory of the vehicle. We end by comparing both results and evaluating if a smartphone can achieve similar accuracy in predicting the future trajectory of a vehicle. Our results show that some smartphones could be used to predict a future position, but the use of their accelerometer sensors introduces some measurements that can be incorrectly interpreted as spatial changes.
Hepatobiliary membrane transporters involving in the formation of cholesterol calculus. (2006)

The down-regulation of BSEP, MRP2, and MDR3 may be correlated with the formation of cholesterol calculus.
Metabolomic Analysis in Inflammatory Bowel Disease: A Systematic Review (2020)

This review provides a summary of metabolomic research in IBD to date, highlighting underlying themes of perturbed gut microbial metabolism and mammalian-microbial co-metabolism associated with disease status.
Capillary zone electrophoresis-multiple reaction monitoring from 100 pg of RAW 264.7 cell lysate digest (2013)

Capillary zone electrophoresis-multiple/single reaction monitoring (CZE-MRM/SRM), which employed an electrokinetically driven sheath-flow electrospray interface, was used for the rapid and highly sensitive detection of protein analytes in complex tryptic digests. MRM channels were developed against a commercial exponential mixture of bovine proteins. Five proteins spanning four orders of magnitude concentration range were confidently detected from only 2.5 ng of the digest mixture; the mass detection limits (S/N = 3) of two detected proteins, alpha-casein and glutamate dehydrogenase were about 600 zmol and 30 amol, respectively. This technique was then applied to a RAW 264.7 cell lysate digest. Three proteins were confidently and reproducibly detected from 100 pg of this digest. The sample amount corresponds to the approximate protein content from a single cell, which suggests that CZE-MRM may be a useful analytical tool in chemical cytometry. In addition to providing highly sensitive detection of proteins in complex mixtures, this system is highly rapid; migration time of the protein digests was less than 10 min.
Description of parallel imaging in MRI using multiple coils (2000)

A general formulation for parallel imaging using multiple coils is derived from the Fourier transform of coil sensitivity functions. This formulation provides a unified account for developed parallel imaging techniques such as subencoding, simultaneous acquisition of spatial harmonics (SMASH), and sensitivity encoding (SENSE), and indicates a guideline for coil configuration and k-space sampling in parallel imaging. The views that can be acquired simultaneously in parallel imaging have to be contained in the spatial frequency band of coil sensitivity functions.
Mechanical properties of apatite formed by acid-base reactions at 37.4°C (2002)

The mechanical properties of monolithic hydroxyapatite were related to porosity, microstructure and composition. The ultimate strength has a logarithmic relationship with the porosity between 4 and 70 vol% pores. The modulus of elasticity is approximately 6-7 GPa for hydroxyapatite and 4-5 GPa for 3.66 wt% carbonate hydroxyapatite.
Growth and characterization of CdZnS thin film buffer layers by chemical bath deposition (2005)

In this paper we report the study of CdZnS thin films grown on the soda-lime glass (SLG) substrates by chemical bath deposition (CBD) process for buffer layer applications in CuGaSe/sub 2/ (CGS) solar cells. Structural, surface morphology, optical, and electrical properties of as-deposited CdZnS films were investigated by XRD, SEM, spectrophotometer, and four probes resistivity measurements as a function of Zn-composition in the solution. The CdZnS films have hexagonal structures. The grain size of CdZnS films was found to increase with increasing Zn-content in the solution. The films with 30% of Zn in the solution showed a better than 80% transmittance for wavelengths longer than 600 nm and film thickness less than 50 nm. The values of energy band gaps obtained are 2.40, 2.55, and 2.70 eV for Zn-content of 0, 30, and 50%, respectively. The resistivity of CdZnS films was found to increase as the Zn content increases.
Studies on CoSalen immobilized onto <i>N</i>‐(4‐methylimidazole)‐chitosan (2006)

Abstract A chitosan (CS) derivative, N ‐(4‐methylimidazole)‐chitosan (MIC), was synthesized, and a cobalt (II) complex of bis(salicylideneethylene diamine), (CoSalen), was immobilized on it. The structure of the polymer‐immobilized CoSalen was characterized by elemental analysis, IR, XPS, fluorescence and ESR spectroscopy. It was demonstrated that the immobilization of CoSalen was realized through the coordination of a nitrogen atom of the pendant group, imidazole in MIC, to the Co(II) in CoSalen. The immobilized polymer complex is more efficient than the corresponding monomeric complex in catalyzing the oxidation of DOPA using oxygen. The results may be attributed to a site isolation effect offered by the supporting polymer chain. A mechanism similar to that for enzymatic catalysis was proposed. © 2006 Wiley Periodicals, Inc. J Appl Polym Sci 101: 2431–2436, 2006
Sol-Gel Deposition and Luminescence Properties of Spherical Phosphors Ca<sub>2</sub>Y<sub>8</sub>(SiO<sub>4</sub>)<sub>6</sub>O<sub>2</sub>:Eu<sup>3+</sup> (2008)

Spherical SiO2 particles were coated with Ca2Y8(SiO4)6O2:Eu3+ phosphor layers through a sol-gel process. The results of XRD (X-ray diffraction) analysis indicated that the phosphors crystallized completely at 1000oC. AFM study revealed that the average grain size is 500 nm. In Ca2Y8(SiO4)6O2:Eu3+ spherical phosphors , the Eu3+ showed its characteristic red emission at 612 nm(5D0-7F2) upon excitation into its charge transfer band of Eu3+-O2- at 242nm.
Fault tolerant control design for a class of multi‐sensor networked control systems (2015)

Summary In this paper, we consider a multi‐sensor networked control configuration with linear plant which is affected by a bounded additive disturbance. Shared network is used for the communication between sensors and controller. It is assumed that the sensors are prone to abrupt faults, while the controller's input may be updated with a varying time‐delay. In order to identify and isolate the sensor(s) providing faulty information, we equip the controller with a set‐based detection and isolation routine. Furthermore, in the case when the network induces time‐delays, control is performed based on the knowledge we have on the mathematical model of the plant. In the presence of model inaccuracies or disturbance, such a control action may not guarantee satisfying performance of the system. Therefore, a stabilising controller with delay compensation has been designed. The functioning of the proposed control algorithm has been illustrated through an example. Copyright © 2015 John Wiley & Sons, Ltd.
A Method for Inferring an Individual’s Genetic Ancestry and Degree of Admixture Associated with Six Major Continental Populations (2013)

The determination of the ancestry and genetic backgrounds of the subjects in genetic and general epidemiology studies is a crucial component in the analysis of relevant outcomes or associations. Although there are many methods for differentiating ancestral subgroups among individuals based on genetic markers only a few of these methods provide actual estimates of the fraction of an individual's genome that is likely to be associated with different ancestral populations. We propose a method for assigning ancestry that works in stages to refine estimates of ancestral population contributions to individual genomes. The method leverages genotype data in the public domain obtained from individuals with known ancestries. Although we showcase the method in the assessment of ancestral genome proportions leveraging largely continental populations, the strategy can be used for assessing within-continent or more subtle ancestral origins with the appropriate data.
Exploiting Structured Knowledge in Text via Graph-Guided Representation Learning (2020)

In this work, we aim at equipping pre-trained language models with structured knowledge. We present two self-supervised tasks learning over raw text with the guidance from knowledge graphs. Building upon entity-level masked language models, our first contribution is an entity masking scheme that exploits relational knowledge underlying the text. This is fulfilled by using a linked knowledge graph to select informative entities and then masking their mentions. In addition we use knowledge graphs to obtain distractors for the masked entities, and propose a novel distractor-suppressed ranking objective which is optimized jointly with masked language model. In contrast to existing paradigms, our approach uses knowledge graphs implicitly, only during pre-training, to inject language models with structured knowledge via learning from raw text. It is more efficient than retrieval-based methods that perform entity linking and integration during finetuning and inference, and generalizes more effectively than the methods that directly learn from concatenated graph triples. Experiments show that our proposed model achieves improved performance on five benchmark datasets, including question answering and knowledge base completion tasks.
A New Cepstral Analysis Procedure of Recovering Excitations for Transient Components of Vibration Signals and Applications to Rotating Machinery Condition Monitoring (2001)

A new cepstral analysis procedure with the complex cepstrum for recovering excitations causing multiple transient signal components from vibration signals, especially from rotor vibration signals, has been developed. Along with the problem of singularity, a major problem of the cepstrum is that it cannot provide a correct distribution of the excitations. To solve these problems, a signal preprocessing method, whose function is to provide a definition for the distribution of the excitations along the quefrency axis and remove singular points from the transform, has been added to the cepstrum analysis. With this procedure, a correct distribution of the excitations can be obtained. An example of application to the condition monitoring of rotor machinery is also presented.
The Stiffness and Structure of Three-Dimensional Printed Hydrogels Direct the Differentiation of Mesenchymal Stromal Cells Toward Adipogenic and Osteogenic Lineages (2014)

The mechanical and physicochemical effects of three-dimensional (3D) printable hydrogels on cell behavior are paramount features to consider before manufacturing functional tissues. We hypothesize that besides good printability and cytocompatibility of a supporting hydrogel for the manufacture of individual tissues, it is equally essential to consider beforehand the desired tissue (bone, cartilage, fat). In light of its application, the structure and stiffness of printable hydrogel matrices influence cell geometry, which in turn impacts the differentiation fate. Embedded human mesenchymal stromal cells in printable type I collagen- and chitosan-agarose blends were induced to differentiate toward osteoblasts and adipocytes. Hydrogels' printability in air versus submerged printing in perfluorocarbon was evaluated according to the height, diameter, uniformity, and stability of 3D printed vertical cylinders. Bipotent differentiation within hydrogels was assessed histologically (morphology, cellularity), by immunohistochemistry (vimentin, smooth muscle actin), two-photon microscopy (spatial distribution), and real-time polymerase chain reaction (ALP, BGLAP, OPN, RUNX2, COL 1, aP2, PPARγ-2). Agarose and agarose blends revealed the most valid printability properties by generating uniform cylinders with an average height of 4 mm. Osteogenic differentiation was preferably achieved in anisotropic soft collagen-rich substrates, whereas adipogenic differentiation mostly occurred in isotropic stiff agarose-rich matrices. The conjugation of type I collagen to agarose with varying ratios is possibly a suitable bioink for a broad range of 3D printed mesenchymal tissues.
Coupled double-distribution-function lattice Boltzmann method for the compressible Navier-Stokes equations (2007)

A coupled double-distribution-function lattice Boltzmann method is developed for the compressible Navier-Stokes equations. Different from existing thermal lattice Boltzmann methods, this method can recover the compressible Navier-Stokes equations with a flexible specific-heat ratio and Prandtl number. In the method, a density distribution function based on a multispeed lattice is used to recover the compressible continuity and momentum equations, while the compressible energy equation is recovered by an energy distribution function. The energy distribution function is then coupled to the density distribution function via the thermal equation of state. In order to obtain an adjustable specific-heat ratio, a constant related to the specific-heat ratio is introduced into the equilibrium energy distribution function. Two different coupled double-distribution-function lattice Boltzmann models are also proposed in the paper. Numerical simulations are performed for the Riemann problem, the double-Mach-reflection problem, and the Couette flow with a range of specific-heat ratios and Prandtl numbers. The numerical results are found to be in excellent agreement with analytical and/or other solutions.
Recent progress in the SPHINX Speech Recognition system (1989)

This paper describes recent improvements in the SPHINX Speech Recognition System. These enhancements include function-phrase modeling, between-word coarticulation modeling, and corrective training. On the DARPA resource management task. SPHINX attained a speaker-independent word accuracy of 96% with a grammar (perplexity 60), and 82% without grammar (perplexity 997).
Coding gaze tracking data with chromatic gradients for VR Exposure Therapy (2007)

This article presents a simple and intuitive way to represent the eye-tracking data gathered during immersive virtual reality exposure therapy sessions. Eye-tracking technology is used to observe gaze movements during virtual reality sessions and the gaze-map chromatic gradient coding allows to collect and use these important information on the subject's gaze avoidance behavior. We presents the technological solution and its relevance for therapeutic needs, as well as the experiments performed to demonstrate its usability in a medical context. Results show that the gaze-map technique is fully compatible with different VR exposure systems and provides clinically meaningful data.
Reliability of the Timeline Followback for cocaine, cannabis, and cigarette use. (2012)

The Timeline Followback (TLFB), a retrospective calendar-based measure of daily substance use, was initially developed to obtain self-reports of alcohol use. Since its inception it has undergone extensive evaluation across diverse populations and is considered the most psychometrically sound self-report measure of drinking. Although the TLFB has been extended to other behaviors, its psychometric evaluation with other addictive behaviors has not been as extensive as for alcohol use. The present study evaluated the test-retest reliability of the TLFB for cocaine, cannabis, and cigarette use for participants recruited from outpatient alcohol and drug treatment programs and the general community across intervals ranging from 30 to 360 days prior to the interview. The dependent measure for cigarette smokers and cannabis users was daily use of cigarettes and joints, respectively, and for cocaine users it was a "Yes" or "No" regarding cocaine use for each day. The TLFB was administered in different formats for different drug types. Different interviewers conducted the two interviews. The TLFB collected highly reliable information about participants' daily use of cocaine, cannabis, and cigarettes from 30, 90, to 360 days prior to the interview. Findings from this study not only suggest that shorter time intervals (e.g., 90 days) can be used with little loss of accuracy, but also add to the growing literature that the TLFB can be used with confidence to collect psychometrically sound information about substance use (i.e., cocaine, cannabis, cigarettes) other than alcohol in treatment- and nontreatment-seeking populations for intervals from ranging up to 12 months prior to the interview.
Conserved Glycines in the C Terminus of MinC Proteins Are Implicated in Their Functionality as Cell Division Inhibitors (2004)

Alignment of 36 MinC sequences revealed four completely conserved C-terminal glycines. As MinC inhibits cytokinesis in Neisseria gonorrhoeae and Escherichia coli, the functional importance of these glycines in N. gonorrhoeae MinC (MinC(Ng)) and E. coli MinC (MinC(Ec)) was investigated through amino acid substitution by using site-directed mutagenesis. Each mutant was evaluated for its ability to arrest cell division and to interact with itself and MinD. In contrast to overexpression of wild-type MinC, overexpression of mutant proteins in E. coli did not induce filamentation, indicating that they lost functionality. Yeast two-hybrid studies showed that MinC(Ec) interacts with itself and MinD(Ec); however, no interactions involving MinC(Ng) were detected. Therefore, a recombinant MinC protein, with the N terminus of MinC(Ec) and the C terminus of MinC(Ng), was designed to test for a MinC(Ng)-MinD(Ng) interaction. Each MinC mutant interacted with either MinC or MinD but not both, indicating the specificity of glycine residues for particular protein-protein interactions. Each glycine was mapped on the C-terminal surfaces (A, B, and C) of the solved Thermotoga maritima MinC structure. We found that MinC(Ec) G161, residing in close proximity to the A surface, is involved in homodimerization, which is essential for MinC function. Glycines corresponding to MinC(Ec) G135, G154, and G171, located within or adjacent to the B-C surface junction, are critical for MinC-MinD interactions. Circular dichroism revealed no gross structural perturbations of the mutant proteins, although the contribution of glycines to protein flexibility and stability cannot be discounted. Using molecular modeling, we propose that exposed conserved MinC glycines interact with exposed residues of the alpha-7 helix of MinD.
DRAM-page based prediction and prefetching (2002)

This paper describes and evaluates DRAM-page based cache-line prediction and prefetching architecture. The scheme takes DRAM access timing into consideration in order to reduce prefetching overhead, amortizing the high cost of DRAM access by fetching two cache lines that reside on the same DRAM-page in a single access. On each DRAM access, one or two cache blocks may be prefetched. We combine three prediction mechanisms: history mechanism, stride, and one block lookahead, make them DRAM page sensitive and deploy them in an effective adaptive prefetching strategy. Our simulation shows that the prefetch mechanism can greatly improve system performance. Using a 32-KB prediction table cache, the prefetching scheme improves performance by 26%-55% on average over a baseline configuration, depending on the memory model. Moreover, the simulation shows that prefetching is more cost-effective than simply increasing L2-cache size or using a one block lookahead prefetching scheme. Simulation results also show that DRAM-page based prefetching yields higher relative performance as processors get faster, making the prefetching scheme more attractive for next generation processors.
Magnetic Properties of Amorphous Magnetic Film on Self-Assembled Convex Pattern (2008)

In this paper, we evaluated magnetic properties of amorphous Tb-Fe-Co magnetic film on self-assembled convex pattern fabricated using conventional sputtering and reactive ion etching equipments. Fabricated pattern had 2-D periodicity of around 28 nm. Tb-Fe-Co film on the pattern indicated that the domain-wall (DW) energy was reduced at the steep region of the pattern, and magnetic reversal behavior became more like Stoner-Wohlfarth mode than DW motion mode. Magnetic force microscope observation showed the magnetic domain whose sizes are as small as 50 nm.