gebhart/patrepeval huggingface dataset:
Performance comparison of index partitioning schemes for distributed query processing (2002)

The benefit of using indexes for processing queries in a database system is well known. The use of indexes in distributed database systems is equally justified. In a distributed database environment a relation may be horizontally partitioned across the nodes of the system and indexes may be created for the fragment of the relation that resides at each node. However as an alternative, one might construct each index on the entire relation, i.e., global indexes, and then partition each index between the nodes. Two approaches are presented for processing such an index partitioning scheme in response to a range query and their performance is compared with the typical scheme. The performance of these schemes is evaluated in terms of the response time, system throughput, network utilization and disk utilization while varying the number of nodes and query.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
High-precision, programmable 1-10 MHz bandwidth, 0-20 dB gain communication channel for digital video applications (2002)

The analog signal processing portion of a digital video demodulation scheme is built in a 5 V BiCMOS process. The channel is both cutoff frequency and gain programmable from 1/spl rarr/10 MHz and 0/spl rarr/20 dB, respectively. The filter is realized as a 4/sup th/ order Gm/C Butterworth lowpass and includes in-package trim for accurate control. A programmable gain amplifier is placed in front of the filter for better S/N performance (>40 dB) and lower intermodulation distortion (>-52 dB). The PSRR of this single-ended channel is better than 40 dB. The channel dissipates 250 mW.
Pars Injuries in Athletes. (2016)

Pars injuries are common causes of low back pain in adolescent athletes. Workup traditionally has included lumbar radiographs with oblique views and single-photon emission computed tomography (SPECT). However, recent literature has demonstrated the accuracy of MRI as a diagnostic modality. Acute injuries may be amenable to bracing with the goal of a healed lesion. Most cases of spondylolysis will result in asymptomatic non-union, though pars repair is an option for symptomatic pars defects without spondylolisthesis.
SMAD4: a predictive marker of PDAC cell permissiveness for oncolytic infection with parvovirus H‐1PV (2009)

Pancreatic ductal adenocarcinoma (PDAC) represents the eighth frequent solid tumor and fourth leading cause of cancer death. Because current treatments against PDAC are still unsatisfactory, new anticancer strategies are required, including oncolytic viruses. Among these, autonomous parvoviruses (PV), like MVMp (minute virus of mice) and H-1PV are being explored as candidates for cancer gene therapy. Human PDAC cell lines were identified to display various susceptibilities to an infection with H-1PV. The correlation between the integrity of the transcription factor SMAD4, mutated in 50% of all PDAC, and H-1PV permissiveness was particularly striking. Indeed, mutation or deletion of SMAD4 dramatically reduced the activity of the P4 promoter and, consequently, the accumulation of the pivotal NS1 protein. By means of DNA affinity immunoblotting, novel binding sites for SMAD4 and c-JUN transcription factors could be identified in the P4 promoter of H-1PV. The overexpression of wild-type SMAD4 in deficient cell lines (AsPC-1, Capan-1) stimulated the activity of the P4 promoter, whereas interference of endogenous SMAD4 function with a dominant-negative mutant decreased the viral promoter activity in wild-type SMAD4-expressing cells (Panc-1, MiaPaCa-2) reducing progeny virus production. In conclusion, the importance of members of the SMAD family for H-1PV early promoter P4 activity should guide us to select SMAD4-positive PDACs, which may be possible targets for an H-1PV-based cancer therapy.
Storage of 1000 holograms with use of a dual-wavelength method (1997)

We demonstrate the storage of 1000 holograms in a memory architecture that makes use of different wavelengths for recording and readout to reduce the grating decay while retrieving data. Bragg-mismatch problems from the use of two wavelengths are minimized through recording in the image plane and using thin crystals. Peristrophic multiplexing can be combined with angle multiplexing to counter the poorer angular selectivity of thin crystals. Dark conductivity reduces the effectiveness of the dual-wavelength method for nonvolatile readout, and constraints on the usable pixel sizes limit this method to moderate storage densities.
Hyperspherical direction cosine change vector analysis (2005)

Abstract Change vector analysis (CVA) partitions spectral change into magnitude and direction components. Although recognized as an effective change detection method, CVA has two limitations. First, it is usually applied to only two bands, and secondly, the selection of a threshold for the magnitude of change can be difficult. These limitations have been addressed through recent research. Hyperspherical direction cosine (HSDC) CVA is an extension of conventional two‐band CVA to many dimensions. Training areas can be used to guide the selection of the change magnitude threshold for discriminating Change and No Change classes. This paper provides a discussion on previous uses of HSDC approaches, and develops a simple procedure for selecting the change magnitude threshold automatically. The application of HSDC CVA and conventional CVA to a Landsat multiSpectral scanner (MSS) Las Vegas, Nevada, dataset is used to demonstrate the application of the approach, and quantify the accuracy gained by incorporating multiple bands in the change analysis. Conventional CVA resulted in an overall accuracy of 69% (Kappa = 0.60), compared to 74% for HSDC CVA (Kappa = 0.68).
Technology trends and the future of broadband multimedia (2010)

Presents a collection of slides covering the topics: mobile TV; HDTV; UHDTV; next generation broadcast systems; un-managed IP networks; broadcast frequency spectrum; and next-generation mobile telecommunications networks.
Understanding Retinopathy of Prematurity: Update on Pathogenesis (2011)

Retinopathy of prematurity (ROP), an ocular disease characterized by the onset of vascular abnormalities in the developing retina, is the major cause of visual impairment and blindness in premature neonates. ROP is a complex condition in which various factors participate at different stages of the disease leading to microvascular degeneration followed by neovascularization, which in turn predisposes to retinal detachment. Current ablative therapies (cryotherapy and laser photocoagulation) used in the clinic for the treatment of ROP have limitations and patients can still have long-term effects even after successful treatment. New treatment modalities are still emerging. The most promising are the therapies directed against VEGF; more recently the use of preventive dietary supplementation with ω-3 polyunsaturated fatty acid may also be promising. Other than pharmacologic and nutritional approaches, cell-based strategies for vascular repair are likely to arise from advances in regenerative medicine using stem cells. In addition to all of these, a greater understanding of other factors involved in regulating pathologic retinal angiogenesis continues to emerge, suggesting potential targets for therapeutic approaches. This review summarizes an update on the current state of knowledge on ROP from our and other laboratories, with particular focus on the role of nitro-oxidative stress and notably trans-arachidonic acids in microvascular degeneration, semaphorin 3 operating as vasorepulsive molecules in the avascular hypoxic retina and in turn impairing revascularization, succinate and its receptor GPR91 in neuron-mediated retinal neovascularization, and ω-3 lipids as modulators of preretinal neovascularization.
Progress toward Price Stability: A 1998 Inflation Report (1999)

Many economists believe that price stability is the primary goal of monetary policy because it is thought to foster maximum sustainable economic growth. Price stability is often said to exist when changes in the general price level cease to be a factor in the decision processes of businesses and individuals. By this definition, price stability was not literally achieved in 1998, as many measures of the price level continued to rise, and inflation expectations were well above zero. Yet in 1998, consumer prices rose at the lowest rate in over a decade, and any upward pressures on inflation were surprisingly subdued. Although many economists still worry about
New, centrally acting dopaminergic agents with an improved oral bioavailability: synthesis and pharmacological evaluation (2000)

This chapter describes the synthesis and in vitro pharmacology of a novel series of dopamine receptor ligands, in which the classical phenylethylamine pharmacophore is replaced by a thienylethylamine moiety. In general, the novel compounds showed moderate affinity for the dopamine D2 and D3 receptors. The results showed that a thienylethylamine moiety can act as a dopamine pharmacophore on these receptors. When the thienylethylamine moiety is fixed in a rigid system the affinity for the dopamine receptor is increased, however, in the tricyclic hexahydrothianaphthoxazine structure, the affinity for the dopamine receptors is diminished. * This chapter is based on: Rodenhuis, N.; Vermeulen, E.S.; Wikstrom, H.V.; Pugsley, T.A.; Wise, L.D.; Dijkstra, D. (2000) Further characterization of structural requirements for ligands at the dopamine D2 and D3 receptor: studies with thienylethylamines as a possible pharmacophore. J. Med. Chem. submitted.
MAN1 and emerin have overlapping function(s) essential for chromosome segregation and cell division in <i>Caenorhabditis elegans</i> (2003)

Emerin and MAN1 are LEM domain-containing integral membrane proteins of the vertebrate nuclear envelope. The function of MAN1 is unknown, whereas emerin is known to interact with nuclear lamins, barrier-to-autointegration factor (BAF), nesprin-1 alpha, and a transcription repressor. Mutations in emerin cause X-linked recessive Emery-Dreifuss muscular dystrophy. Emerin and MAN1 homologs are both conserved in Caenorhabditis elegans, but loss of Ce-emerin has no detectable phenotype. We therefore used C. elegans to test the hypothesis that Ce-MAN1 overlaps functionally with Ce-emerin. Supporting this model, Ce-MAN1 interacted directly with Ce-lamin and Ce-BAF in vitro and required Ce-lamin for its nuclear envelope localization. Interestingly, RNA interference-mediated removal of approximately 90% of Ce-MAN1 was lethal to approximately 15% of embryos. However, in the absence of Ce-emerin, approximately 90% reduction of Ce-MAN1 was lethal to all embryos by the 100-cell stage, with a phenotype involving repeated cycles of anaphase chromosome bridging and cytokinesis ["cell untimely torn" (cut) phenotype]. Immunostaining showed that the anaphase-bridged chromatin specifically retained a mitosis-specific phosphohistone H3 epitope and failed to recruit detectable Ce-lamin or Ce-BAF. These findings show that LEM domain proteins are essential for cell division and that Ce-emerin and Ce-MAN1 share at least one and possibly multiple overlapping functions, which may be relevant to Emery-Dreifuss muscular dystrophy.
Impact of HIV infection on mycobacterial disease. (1992)

The current epidemic of human immunodeficiency virus (HIV) infection and acquired immunodeficiency syndrome has resulted in a worldwide resurgence of tuberculosis. In the United States, the number of new cases of tuberculosis has increased in the past five years, leading to a cumulative excess of about 15,000 cases. The clinical and epidemiologic picture of tuberculosis in AIDS patients differs drastically from the standard presentation of tuberculosis cases in HIV-negative patients. The diagnosis and management of tuberculosis, particularly atypical mycobacterial infections, present a challenge in HIV-infected patients. Prevention of the transmission of disease is a major concern. Since atypical mycobacterial infection and disease pose a greater management challenge, this article summarizes diagnosis and treatment of atypical mycobacterial infection in HIV-positive patients.
FreeGlass for developers, “haccessibility”, and Digital Eye Glass + Lifeglogging research in a (sur/sous)veillance society (2013)

This paper presents “FreeGlass”, a hands-free user-buildable wearable computer system based on Mann's “Digital Eye Glass” (also known as EyeTap) concept developed 35 years ago. Like Mann's “Eye Glass”, FreeGlass is based on free and Open Source principles consistent with a free and open i-Society. FreeGlass is suitable for researchers and creators of AR (Augmediated Reality) Glass, LifeGlogging, etc. in the information society. Two example applications of FreeGlass are also presented: Reality User Interface; and “ALIBEye”, a digital alibi through sousveillance (inverse surveillance). We note the potential for FreeGlass to bring about a transition from a surveillance society (cameras affixed to land and buildings), to a sousveillance-society (cameras held, carried, or worn by individuals). Important elements of a balanced sur/sous-veillance society are also presented with a view toward a middle-ground between a surveillance-only society where large entities record interactions but forbid individuals from keeping their own record of their sensory information, and the coming sousveillance society in which individuals are also equipped with veillance capacity, and the capacity to capture AND authenticate their own recordings as digital alibis.
The Chikungunya Virus Capsid Protein Contains Linear B Cell Epitopes in the N- and C-Terminal Regions that are Dependent on an Intact C-Terminus for Antibody Recognition (2015)

Chikungunya virus (CHIKV) is an arthropod-borne agent that causes severe arthritic disease in humans and is considered a serious health threat in areas where competent mosquito vectors are prevalent. CHIKV has recently been responsible for several millions of cases of disease, involving over 40 countries. The recent re-emergence of CHIKV and its potential threat to human health has stimulated interest in better understanding of the biology and pathogenesis of the virus, and requirement for improved treatment, prevention and control measures. In this study, we mapped the binding sites of a panel of eleven monoclonal antibodies (mAbs) previously generated towards the capsid protein (CP) of CHIKV. Using N- and C-terminally truncated recombinant forms of the CHIKV CP, two putative binding regions, between residues 1-35 and 140-210, were identified. Competitive binding also revealed that five of the CP-specific mAbs recognized a series of overlapping epitopes in the latter domain. We also identified a smaller, N-terminally truncated product of native CP that may represent an alternative translation product of the CHIKV 26S RNA and have potential functional significance during CHIKV replication. Our data also provides evidence that the C-terminus of CP is required for authentic antigenic structure of CP. This study shows that these anti-CP mAbs will be valuable research tools for further investigating the structure and function of the CHIKV CP.
Radiometric calibration with illumination change for outdoor scene analysis (2008)

The images of an outdoor scene collected over time are valuable in studying the scene appearance variation which can lead to novel applications and help enhance existing methods that were constrained to controlled environments. However, the images do not reflect the true appearance of the scene in many cases due to the radiometric properties of the camera : the radiometric response function and the changing exposure. We introduce a new algorithm to compute the radiometric response function and the exposure of images given a sequence of images of a static outdoor scene where the illumination is changing. We use groups of pixels with constant behaviors towards the illumination change for the response estimation and introduce a sinusoidal lighting variation model representing the daily motion of the sun to compute the exposures.
Mechanical Behaviour at Low Strains of LDPE Foams with Cell Sizes in the Microcellular Range: Advantages of Using These Materials in Structural Elements (2008)

This paper presents the production method and the compressive mechanical response at low strains for a collection of polyethylene foams with high densities and cell sizes in the microcellular range. The materials were produced using an improved compression moulding technique that allows and independent control of density and cell size. The materials had a relative density between 0.27 and 0.92, an homogeneous and multi-structured cellular structure with dense skin and foamed core and cell sizes in the range 30 to 100 microns. The Young's modulus decreased with density. For relative densities higher than 0.7, the reduced Young's modulus of the foams was higher than that of the solid. In addition, it has been proved that variations in the cell size at constant density did not influence the Young's modulus. The advantages of using these materials for the production of plastic pipes have been analysed. In comparison with a solid pipe a reduction of the weight of foamed pipes loaded in compression of up to 40% can be reached.
Transport Characteristics of Si Nanowires in Bulk Silicon and SOI Wafers (2006)

Silicon nanowires (SiNW) were fabricated on bulk Silicon and SOI wafers by means of conventional Si process technology. The nanowires were formed by stress-limited oxidation of Si beams pre-patterned on the wafer. Single or double vertically self-aligned wires were obtained depending on the bulk or SOI wafer used and also on the depth of silicon beam etched. The resulting nanowires exhibit triangular cross-section that can be converted to circular shape by annealing at high temperatures, exploiting the visco-elastic properties of SiO <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> and Si. Electrical measurements on single nanowire show that the resistance scales with length demonstrating consistent cross-sectional dimension in wires of different length. The nanowires formed on SOI wafers were also characterized as channels in FET configuration, using substrate as gate electrode. This technique can be exploited for realizing several nano-electronics, NEMS and biosensor applications in bulk silicon or SOI wafers, all in a CMOS compatible manner.
Implementation of a DSP based real-time estimator of induction motors rotor time constant (2002)

Implementation of ac drives insensitive to parameter variations is an important need in the field of high performance drives. For drives controlled by the indirect rotor flux oriented control method (IRFOC), the rotor time constant (/spl tau//sub r/ = L/sub r//R/sub r/) exerts a dominant role in the loss of dynamic performance and its variation results in an undesirable coupling between flux and torque of the machine. This paper presents a new scheme for on-line estimation of rotor time constant using dq representation of the model in the stationary reference frame and measurements of accessible motor variables only (voltages, currents and speed). The estimator is tested by simulation in the MATLAB/SIMULINK environment and validated experimentally on a 1/4 hp squirrel cage motor and a 1/4 hp wound rotor motor with implementation on a TMS320C31 digital signal processor.
Arsenic Removal from Water Using Industrial By‐Products (2013)

In this study, removal of arsenic ions using two industrial by‐products as adsorbents is represented. Removal of As(III) and As(V) from water was carried out with industrial by‐products: residual from the groundwater treatment process, iron‐manganese oxide coated sand (IMOCS), and blast furnace slag from steel production (BFS), both inexpensive and locally available. In addition, the BFS was modified in order to minimise its deteriorating impact on the initial water quality. Kinetic and equilibrium studies were carried out using batch and fixed‐bed column adsorption techniques under the conditions that are likely to occur in real water treatment systems. To evaluate the application for real groundwater treatment, the capacities of the selected materials were further compared to those exhibited by commercial sorbents, which were examined under the same experimental conditions. IMOCS was found to be a good and inexpensive sorbent for arsenic, while BFS and modified slag showed the highest affinity towards arsenic. All examined waste materials exhibited better sorption performances for As(V). The maximum sorption capacity in the batch reactor was obtained for blast furnace slag, 4040 μ gAs(V)/g.
Tampa Electric Neural Network Sootblowing (2002)

of the Big Bend units helped identify intelligent sootblowing as a suitable application to achieve the desired objectives. The existing sootblower control philosophy uses sequential schemes, whose frequency is either dictated by the control room operator or is timed based. The intent of this project is to implement a neural network based intelligent sootblowing system, in conjunction with state-of-the-art controls and instrumentation, to optimize the operation of a utility boiler and systematically control boiler fouling. Utilizing unique, on-line, adaptive technology, operation of the sootblowers can be dynamically controlled based on real-time events and conditions within the boiler. This could be an extremely cost-effective technology, which has the ability to be readily and easily adapted to virtually any pulverized coal fired boiler. Through unique on-line adaptive technology, Neural Network-based systems optimize the boiler operation by accommodating equipment performance changes due to wear and maintenance activities, adjusting to fluctuations in fuel quality, and improving operating flexibility. The system dynamically adjusts combustion setpoints and bias settings in closed-loop supervisory control to simultaneously reduce NO{sub x} emissions and improve heat rate around the clock.
An 8 Channel Transmit Coil for Transmit Sense at 3T (2006)

V. Alagappan, G. C. Wiggins, A. Potthast, K. Setsompop, E. Adalsteinsson, L. L. Wald MGH Department of Radiology, A. A. Martinos Center for Biomedical Imaging, Charlestown, MA, United States, Siemens Medical Solutions, Charlestown, MA, United States, Department of Electrical and Computer Engg, MIT, Cambridge, MA, United States, Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA, United States
Longitudinal plasma amyloid beta in Alzheimer's disease clinical trials (2014)

We found no support for the utility of plasma Aβ as a prognostic factor or correlate of cognitive change. Analysis of stored specimens requires careful standardization and experimental design, but plasma Aβ may prove useful in pharmacodynamic studies of antiamyloid drugs.
Formic Acid Oxidation on Ultrathin Pd Films on Au(<i>hkl</i>) and Pt(<i>hkl</i>) Electrodes (1996)

The oxidation of formic acid on thin, epitaxially-grown Pd overlayers on Au and Pt single crystal electrodes was studied as a function of overlayer thickness ranging from submonolayer coverages up to the equivalent of 10 monolayers. The results were compared with those for massive Pd single crystal surfaces. The electrocatalytic properties of the Pd overlayers were found to depend markedly on their thickness and on their crystallographic orientation. Pd(100) showed the highest catalytic activity of all three low-index faces, and Pd films on Pt(hkl), even when two or three layers thick, generally exhibited a much higher activity than Pd films on Au(hkl) or massive Pd(hkl). In all cases a high resistivity of the Pd surfaces against poisoning by CO was observed, which makes Pd an interesting alternative to the often quickly deactivated Pt as catalyst for organic fuel cell reactions.