gebhart/patrepeval huggingface dataset:
PC<sup>2</sup>A: Predicting Collective Contextual Anomalies via LSTM With Deep Generative Model (2019)

Proactive anomaly detection and diagnosis play an essential role in ensuring the security and stability of a large-scale information technology (IT) system with thousands or even millions of components that are interacting with each other. Collective contextual anomalies (CCAs) carry the characteristics of both collective and contextual anomalies. This type of anomalies is common in IT system monitoring, often manifested as security risks to be ameliorated, service outages to be eliminated, or stragglers to be mitigated. However, most existing studies emphasize primarily on the detection of point anomalies while the prediction or early detection of CCA has been an underexplored topic. In this paper, we propose a framework for discovering and studying CCAs in multiple time series based on a combination of semi-supervised deep learning, time series modeling, and graph analysis. A primary advantage of the proposed framework is that it can effectively predict CCAs with no human intervention. In addition, the performance of the proposed method can be further enhanced via learning from a small amount of anomalous training data, if it is available. Finally, the proposed framework is of low computational complexity and is thus particularly suitable for large-scale data streams. Simulation studies are carried out to reveal the superior performance of the proposed method and underscore the significant benefits of combining deep neural networks with time series analysis and graph models for the prediction and analysis of CCAs.
Influence of Aspirin to the incidence of cardiovascular and cerebrovascular events after healing of diabetic foot ulcer (2010)

Objective To explore the influence of Aspirin to the incidence of cardiovascular and cerebrovas-cular events after healing of diabetic foot ulcer. Methods 54 patients with diabetic foot ulcer were followed up after cure. Depending on whether continued use of Aspirin,54 cases were divided into two groups and observed 1 year,3 years,5 years later. Then the incidence of cardiovascular and cerebrovascular events were compared between two groups. Results The incidence of cardiovascular and cerebrovascular events were significantly different between two groups(P<0. 05) ,and it increased significantly in the group which were not continued with Aspirin after 1-year. Conclusion Aspirin playedan important role in preventing incidence of cardiovascular and cerebrovascula events after healing of diabetic foot ulcer.

Key words: 
Aspirin;  Diabetic foot;  Cardio-cerebrovascular events
Treatment With Cholinesterase Inhibitors and Memantine of Patients in the Alzheimer's Disease Neuroimaging Initiative (2011)

clinicalTrials.gov Identifier: NCT00106899.
Tunnel magnetoresistance of disordered, low-moment Co2MnSi Heusler alloy thin films (2005)

Thin films of Co(1−x−y)MnxSiy (x=0.18–0.26 and y=0.23–0.29) were deposited from elemental targets onto thermal-oxidized Si substrates at room temperature using dc magnetron cosputtering. The as-deposited films appear to be amorphous showing no distinguishable peaks in x-ray diffraction, and the magnetic moment at room temperature is nearly zero. Despite of its low magnetic moment (less than 0.001μB per formula), the disordered Heusler magnetic tunnel junctions show tunnel magnetoresistance ratios as large as 10% at room temperature. The dependence of the tunnel magnetoresistance ratio on compositions x and y is also reported.
Differential effects of NGF and NT-3 on embryonic trigeminal axon growth patterns (2000)

We examined the effects of neurotrophins nerve growth factor (NGF) and neurotrophin-3 (NT-3) on trigeminal axon growth patterns. Embryonic (E13-15) wholemount explants of the rat trigeminal pathway including the whisker pads, trigeminal ganglia, and brainstem were cultured in serum-free medium (SFM) or SFM supplemented with NGF or NT-3 for 3 days. Trigeminal axon growth patterns were analyzed with the use of lipophilic tracer DiI. In wholemount cultures grown in SFM, trigeminal axon projections, growth patterns, and differentiation of peripheral and central targets are similar to in vivo conditions. We show that in the presence of NGF, central trigeminal axons leave the tract and grow into the surrounding brainstem regions in the elongation phase without any branching. On the other hand, NT-3 promotes precocious development of short axon collaterals endowed with focal arbors along the sides of the central trigeminal tract. These neurotrophins also affect trigeminal axon growth within the whisker pad. Additionally, we cultured dissociated trigeminal ganglion cells in the presence of NGF, NT-3, or NGF+NT-3. The number of trigeminal ganglion cells, their size distribution under each condition were charted, and axon growth was analyzed following immunohistochemical labeling with TrkA and parvalbumin antibodies. In these cultures too, NGF led to axon elongation and NT-3 to axon arborization. Our in vitro analyses suggest that aside from their survival promoting effects, NGF and NT-3 can differentially influence axon growth patterns of embryonic trigeminal neurons.
Variable aperture stop based on the design of a single chamber silicone membrane lens with integrated actuation (2011)

In this Letter we report on the fabrication and testing of an extremely thin variable aperture stop based on the design of a single chamber adaptive membrane lens with integrated actuation. The aperture consists of a ring-shaped piezoelectric bending actuator with an elastic silicone membrane in the center. The formed cavity is filled with a nontransparent fluid and sealed with a glass platelet. In a voltage range up to 80 V, an opening of the aperture of 4.55 mm in diameter is obtained. The transmission in comparison to a standard mechanical aperture stop is maximum 6% lower.
Ground Water Issue Behavior of Metals in Soils (1992)

The Regional Superfund Ground-Water Forum is a group of scientists, representing EPA's Regional Superfund Offices, organized to exchange up-to-date information related to ground-water remediation at Superfund sites. One of the major issues of concern to the Forum is the mobility of metals in soils as related to subsurface remediation. For the purposes of this Issue Paper, those metals most commonly found at Superfund sites will be discussed in terms of the processes affecting their behavior in soils as well as laboratory methods available to evaluate this behavior. The retention capacity of soil will also be discussed in terms of the movement of metals between the other environmental compartments including ground water, surface water, or the atmosphere. Long-term changes in soil environmental conditions, due to the effects of remediation systems or to natural weathering processes, are also discussed with respect to the enhanced mobility of metals in soils. For further information contact Bert Bledsoe (405) 332-8800 or FTS 700-743-2324 at RSKERL-Ada.
Algorithm 540: PDECOL, General Collocation Software for Partial Differential Equations [D3] (1979)

The basic purpose of this paper is to describe and discuss PDECOL, which is a new computer software package for numerically solving coupled systems of nonlinear partial differential equations (PDE's) in one space and one time dimension. The package implements finite element collocation methods based on piecewise polynomials for the spatial discretization techniques. The time integration process is then accomplished by widely acceptable procedures
Cavity resonances of metal-dielectric-metal nanoantennas (2009)

We propose a new design of optical nanoantennas and numerically study their optical properties. The nanoantennas are composed of two cylindrical metal nanorods stacked vertically with a circular dielectric disk spacer. Simulation results show that when the dielectric disk is less than 5nm in thickness, such nanoantennas exhibit two types of resonances: one corresponding to antenna resonance, the other corresponding to cavity resonances. The antenna resonance generates a peak in scattering spectra, while the cavity resonances lead to multiple dips in the scattering spectra. The cavity resonant frequency can be tuned by varying the size of the dielectric disk. The local field enhancement inside the cavity is maximized when the diameter of the dielectric disk is roughly half that of the rod and when the cavity and antenna resonant frequencies coincide with each other. This new nanoantenna promises applications in single molecule surface enhanced Raman spectroscopy (SERS) owing to its high local field enhancements and large scale manufacturability.
Leptin Modulates the Glucocorticoid-Induced Ovarian Steroidogenesis<sup>1</sup> (1999)

Leptin regulates food intake and other activities through its hypothalamic receptor. Leptin receptors are also found in other organs, including the ovary. Direct effects of leptin in ovarian steroid production were studied in primary rat granulosa cells and in rat and human granulosa cell lines. Leptin (0.6-18 nM) suppressed ovarian steroid synthesis costimulated by FSH and dexamethasone. Production of pregnenolone, progesterone, and 20alpha-hydroxy-4-pregnen-3-one was inhibited by leptin. This inhibition was due at least in part to reduced expression of adrenodoxin, a component of the P450scc system enzyme. Costimulation of progesterone production by forskolin and dexamethasone was also inhibited by leptin, whereas the forskolin-induced cAMP production was not affected. We find that leptin induces c-Jun expression and attenuates the transcriptional activity of the glucocorticoid receptor (GR) in granulosa cells. Elevation of c-Jun expression by other means, e.g. 12-O tetradecanoyl-phorbol-13-acetate or transfecting with a c-Jun expression vector, abolished the transcriptional activity of the GR. A leptin-induced elevation of c-Jun modulates the transcriptional activity of the GR, possibly leading to the observed attenuation of steroidogenesis. It was recently shown that glucocorticoids stimulate leptin expression in vivo, which in turn, inhibits cortisol synthesis. A direct action of leptin on the ovary is an additional element of a regulatory network that maintains the homeostasis of steroid production.
Genetic and Biochemical Evidence for a Novel Avermectin-sensitive Chloride Channel in Caenorhabditis elegans (1997)

Avermectins are a class of macrocyclic lactones that is widely used in crop protection and to treat helminth infections in man and animals. Two complementary DNAs (GluClalpha and GluClbeta) encoding chloride channels that are gated by avermectin and glutamate, respectively, were isolated from Caenorhabditis elegans. To study the role of these subunits in conferring avermectin sensitivity we isolated a mutant C. elegans strain with a Tc1 transposable element insertion that functionally inactivated the GluClalpha gene (GluClalpha::Tc1). GluClalpha::Tc1 animals exhibit a normal phenotype including typical avermectin sensitivity. Xenopus oocytes expressing GluClalpha::Tc1 strain mRNA elicited reduced amplitude avermectin and glutamate-dependent chloride currents. Avermectin binding assays in GluClalpha::Tc1 strain membranes showed the presence of high affinity binding sites, with a reduced Bmax. These experiments suggest that GluClalpha is a target for avermectin and that additional glutamate-gated and avermectin-sensitive chloride channel subunits exist in C. elegans. We isolated a cDNA (GluClalpha2) encoding a chloride channel that shares 75% amino acid identity with GluClalpha. This subunit forms homomeric channels that are gated irreversibly by avermectin and reversibly by glutamate. GluClalpha2 coassembles with GluClbeta to form heteromeric channels that are gated by both ligands. The presence of subunits related to GluClalpha may explain the low level and rarity of target site involvement in resistance to the avermectin class of compounds.
Recovery of heart rate following intense dynamic exercise (2009)

The Olympic biathlon is a very demanding physical event that requires high oxygen delivery, good cross-country skiing skills and skilful use of a rifle. Like all high-performance endurance athletes, high cardiac vagal tone is a characteristic and extends the range over which cardiac output can increase. In the biathlete, however, the enhanced vagal control of the heart also allows a strategy for better control of stability needed for accurately firing a rifle at the end of each lap of the race. The role of endurance training, central command, reflexes from muscle, and of the carotid-cardiac baroreceptor reflex in changing vagal tone during intense exercise and recovery is discussed.
Characterization and Activity of an Immobilized Antimicrobial Peptide Containing Bactericidal PEG-Hydrogel (2014)

A single step immobilization-polymerization strategy of a highly active antimicrobial peptide into a soft hydrogel network on a poly(ethylene terephthalate) surface using thiol-ene chemistry is described. The bactericidal hydrogel was molecularly characterized via Coomassie and Lowry assay protein staining agents as well as by X-ray photoelectron spectroscopy. The bactericidal activity was established against Staphylococcus aureus and Staphylococcus epidermidis, two bacterial strains commonly associated with biomaterial infections. To gain further insight into the biological stability, the hydrogels were incubated with human serum prior to activity testing without loss of activity. These studies revealed a promising bactericidal hydrogel with good stability under physiological conditions.
Percutaneous transperineal placement of gold 198 seeds for treatment of carcinoma of the prostate (1987)

Thirty-one patients have been treated for carcinoma of the prostate with 198Au seeds placed transperineally using transrectal ultrasonic guidance. Twenty patients have been followed postoperatively for periods ranging from 3 to 31 months, with an average follow-up time of 12 months. Cumulative dose of radiation to the prostate calculated by dosimetry was either 9,000 rads or 15,000 rads. Serial transrectal ultrasound examinations performed on these patients showed a decrease in prostate size in all patients within 6 months of treatment, with a statistically significant decrease observed between the third and sixth months. No significant difference in amount or rate of tumor regression was noted when tumor stage and grade were correlated to volume decrease after treatment. Patients who received the larger doses of radiation (15,000 rads) showed a significantly greater rate of decline in prostatic volume than those who received 9,000 rads. Seven patients underwent prostate biopsy between 12 and 18 months after treatment; six biopsies showed residual tumor. Complications after treatment included urinary retention because of prostatic edema (three), radiation urethritis (three), and rectal ulceration (one). Transperineal placement of 198Au is well tolerated and offers an alternative to external beam radiation for treatment of carcinoma of the prostate.
Formation of reconfigurable optical channel waveguides and beam splitters on top of proton-implanted lithium niobate crystals using spatial dark soliton-like structures (2008)

We report on the formation of reconfigurable optical channel waveguides (including straight stripes and Y-branches) on top of iron-doped lithium niobate crystals. The sample surface is first implanted by 500 keV protons to form a planar waveguide showing a propagation loss of ∼1.6 dB cm−1 after modest post-implantation annealing. Afterwards, the sample surface is illuminated with well-defined stripe patterns (straight channels, beam splitters) of green light using lithographic masks. Due to the photovoltaic effect in lithium niobate resulting in negative index changes in illuminated regions, waveguide layers are formed in the non-illuminated regions perpendicular to the planar waveguide in the same way as it occurs in the dark spatial soliton regime. In this way two-dimensional waveguides are formed in the overlap region on top of the crystal that may be used for reconfigurable optical interconnections and splitters.
Experimental evaluation of active filter control incorporating on-line impedance measurement (2004)

This paper describes the use of on-line impedance estimation for power quality improvement. The impedance measurement technique can be embedded into the normal operation of an active shunt filter, to provide regular updates to the estimate of the supply impedance to source. In this work, the supply impedance estimates are then use in conjunction with the measurement of supply voltage, to generate the reference currents for the active shunt filter. Experimental results show both the accuracy of the impedance measurement, and the effective operation of the active filter in reducing the voltage distortion at the point of connection.
A Meeting Scheduler for Office Automation (1989)

Scheduling of meetings is one of the basic functions demanded in office automation, since office workers spend much time on meetings. This paper discusses a schedufkng problem of meetings and presents a meeting scheduler for office automation which provides an automatic mechanism for updating a schedule of meetings.
Singular value decomposition of optically-mapped cardiac rotors and fibrillatory activity (2015)

Our progress of understanding how cellular and structural factors contribute to the arrhythmia is hampered in part because of controversies whether a fibrillating heart is driven by a single, several, or multiple number of sources, and whether they are focal or reentrant, and how to localize them. Here we demonstrate how a novel usage of the neutral singular value decomposition (SVD) method enables the extraction of the governing spatial and temporal modes of excitation from a rotor and fibrillatory waves. Those modes highlight patterns and regions of organization in the midst of the otherwise seemingly-randomly propagating excitation waves. We apply the method to experimental models of cardiac fibrillation in rabbit hearts. We show that the SVD analysis is able to enhance the classification of the heart electrical patterns into regions harboring drivers in the form of fast reentrant activity and other regions of by-standing activity. This enhancement is accomplished without any prior assumptions regarding the spatial, temporal or spectral properties of those drivers. The analysis corroborates that the dominant mode has the highest activation rate and further reveals a new feature: A transfer of modes from the driving to the passive regions resulting in a partial reaction of the passive region to the driving region.
Scatchard analysis of fluorescent concanavalin a binding to lymphocytes (1995)

Standard Scatchard analysis of ligand binding to cell receptors requires the use of isotopes and is imprecise at low ligand concentrations. To evaluate the feasibility of Scatchard analysis via fluorescence flow cytometry, the binding of fluorescein isothiocyanate-derivatized concanavalin A (FITC-ConA) to murine lymphocytes at 4 degrees C was compared to 125I-ConA binding. A FACS IV flow cytometer (Becton-Dickinson, Mountain View, CA) was used for analysis of cells after fluorescent ligand binding. A simple spectrophotometric technique was used to calibrate the relation between cytometer-determined fluorescence and ligand binding per cell. As FITC-ConA binding showed a quasi-Gaussian distribution, the mean number of molecules bound per cell was easily calculated. Scatchard analysis of FITC-ConA binding yielded results (1.9 x 10(6) receptors/cell, K = 3.6 x 10(-15)) similar to those obtained with 125I-ConA (1.4 x 10(6) receptors/cell, K = 5.2 x 10(-15)). Cytometric Scatchard plots showed less scatter and seemed more precise, suggesting superiority to radioactive ligand measurements, particularly at low ligand concentrations.
ChemInform Abstract: PREPARATION OF PYRONOCONDENSED 2‐PYRIDONE, COUMARINS, AND 2‐QUINOLONES BY USING THE KAPPE‐MAYER MODIFICATION OF THE VON PECHMANN REACTION (1982)

Abstract Die Pyridone (I) kondensieren mit den Acetessigesterderivaten (II) in Gegenwart von Ammoniumacetat zu den Pyronopyridonen (III).
Size Evolution of Gold Nanoparticles in a Millifluidic Reactor (2011)

The size evolution of gold nanoparticles in a millifluidic reactor is investigated using spatially resolved transmission electron microscopy (TEM). The experimental data is supported by numerical simulations, carried out to study the residence-time distribution (RTD) of tracers that have the same properties as Au ions. Size and size distribution of the particles within the channels are influenced by the mixing zones as well as the RTD. However, the Au nanoparticles obtained show a broader size distribution even at the shortest investigated residence time of 3.53 s, indicating that in addition to surface growth reaction kinetics also plays an important role. The comparison of time resolved particle growth within the millifluidic channel with flask-based reactions reveals that the particle size can be controlled better within millifluidic channels. Overall, the results indicate potential opportunities to utilize easy to fabricate millifluidic reactors for the synthesis of nanoparticles, as well as as for carrying out time resolved kinetic studies.
1-Phenylcarbamoyl-2-pyrazolines: a new class of insecticides. 2. Synthesis and insecticidal properties of 3,5-diphenyl-1-phenylcarbamoyl-2-pyrazolines (1978)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT1-Phenylcarbamoyl-2-pyrazolines: a new class of insecticides. 2. Synthesis and insecticidal properties of 3,5-diphenyl-1-phenylcarbamoyl-2-pyrazolinesRolf Van Hes, Kobus Wellinga, and Arnold C. GrosscurtCite this: J. Agric. Food Chem. 1978, 26, 4, 915–918Publication Date (Print):July 1, 1978Publication History Published online1 May 2002Published inissue 1 July 1978https://pubs.acs.org/doi/10.1021/jf60218a015https://doi.org/10.1021/jf60218a015research-articleACS PublicationsRequest reuse permissionsArticle Views177Altmetric-Citations37LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts