gebhart/patrepeval huggingface dataset:
Synthesis and Characterization of PVP/Eu<sub>4/3</sub>L(phen)•2H<sub>2</sub>O Luminescent Complex (2011)

Rare earth europium (Eu(III))-pyromellitic acid (H4L)-1,10-phenanthroline (phen) ternary luminescent complex has been synthesized in polyvinylpyrrolidone (PVP) matrix by precipitation method. The chemical constitution of the complex has been demonstrated as PVP/EuL4/3L(phen)•2H2O by a combination of elemental analysis, inductively coupled plasma-atomic emission spectroscopy (ICP-AES) and Fourier-transform infrared spectroscopy (FT-IR). X-ray diffraction analysis (XRD) has shown that the complex is a new kind of crystal whose structure is totally different from two ligands. The morphology of the complex has been investigated by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The results have shown that the complex has a rodlike crystal structure and the diameter of the rod is about 400 nm. Thermogravimetric analysis (TG) has indicated that the luminescent complex is thermally stable below 300 °C. Photoluminescence spectra (PL) have revealed that the complex can emit Eu3+ characteristic red fluorescence under ultraviolet excitation.
Performance of Two Fluorescence-Based Real-Time Bioaerosol Detectors: BioScout vs. UVAPS (2013)

A 405 nm diode laser-based on-line bioaerosol detector, BioScout, was tested and compared with the Ultraviolet Aerodynamic Particle Sizer (UVAPS). Both instruments are based on laser-induced fluorescence of particles. Only a fraction of microbial particles produce enough fluorescence light to be detected by the instruments. This fluorescent particle fraction (FPF) is aerosol and instrument specific. The FPF values for common bacterial and fungal spores and biochemical particles were experimentally determined for both instruments. The BioScout exhibited higher FPF values for all the test aerosols except coenzyme NADH. The difference was higher for smaller particles. The FPF values of fungal spores and bacteria varied between 0.34 to 0.77 and 0.13 to 0.54 for the BioScout and the UVAPS, respectively. The results indicate that the 405 nm diode laser is a useful excitation source for fluorescence-based real-time detection of microbial aerosols. The FPF results of this study can be utilized to estimate the actual concentrations of bacterial and fungal spores in fluorescence-based ambient measurements. Copyright 2014 American Association for Aerosol Research
Multistate Outbreak of Fusarium Keratitis Associated With Use of a Contact Lens Solution (2006)

The findings from this investigation indicate that this outbreak of Fusarium keratitis was associated with use of ReNu with MoistureLoc contact lens solution. Contact lens users should not use ReNu with MoistureLoc.
SSPFA: effective stack smashing protection for Android OS (2019)

In this paper, we detail why the stack smashing protector (SSP), one of the most effective techniques to mitigate stack buffer overflow attacks, fails to protect the Android operating system and thus causes a false sense of security that affects all Android devices. We detail weaknesses of existing SSP implementations, revealing that current SSP is not secure. We propose SSPFA, the first effective and practical SSP for Android devices. SSPFA provides security against stack buffer overflows without changing the underlying architecture. SSPFA has been implemented and tested on several real devices showing that it is not intrusive, and it is binary-compatible with Android applications. Extensive empirical validation has been carried out over the proposed solution.
Hybrid 2D–0D MoS<sub>2</sub>–PbS Quantum Dot Photodetectors (2014)

A hybrid phototransistor consisting of colloidal PbS quantum dots and few layers of MoS2 (≥2 layers) is demonstrated. The hybrid benefits from tailored light absorption in the quantum dots throughout the visible/near infrared region, efficient charge-carrier separation at the p-n interface, and fast carrier transport through the MoS2 channel. It shows responsivity of up to 10(6) A W(-1) and backgate-dependent sensitivity.
Tuning stiffness of cell-laden hydrogel via host–guest interactions (2016)

We report a dynamic hydrogel system with on-demand tunable matrix stiffness. The hydrogels are formed by thiol-allylether photo-click reaction using thiolated poly(vinyl alcohol) (TPVA), 4-arm poly(ethylene glycol)-allylether (PEG4AE), and mono-functional β-cyclodextrin-allylether (βCDAE). Adamantane-functionalized 4-arm PEG (PEG4AD) is used to stiffen hydrogels, whereas unmodified βCD is used to induce gel softening. The stiffening and softening processes are fully reversible and these hydrogels are ideal for investigating the effect of matrix mechanics on cell fate processes.
A Novel SimpleProbe PCR Assay for Detection of Mutations in the 23S rRNA Gene Associated with Macrolide Resistance in Mycoplasma genitalium in Clinical Samples (2016)

Macrolide-resistant strains of Mycoplasma genitalium are an increasing problem throughout the world, and the implementation of a rapid and sensitive assay for mutation detection to guide treatment is needed. Macrolide-resistant strains have been shown to contain base substitutions in positions 2058 and 2059 (Escherichia coli numbering) in region V of the 23S rRNA gene. In this study, we present a SimpleProbe PCR followed by melting curve analysis to differentiate between macrolide-resistant mutants and wild types. The assay was performed on 159 Mycoplasma genitalium-positive samples, and the results were compared with DNA sequencing. We also looked at the prevalence of macrolide-resistant strains in a Norwegian population. Of 139 samples characterized successfully by sequencing, 54 (39%) were wild types and 85 (61%) were mutants, consisting of 59 (42%) A2059G, 24 (17%) A2058G, 1 (1%) A2058T, and 1 (1%) A2059C mutation. The melting curve analysis correctly differentiated between wild-type and mutant strains in all cases, but it could not identify the different mutant types. The SimpleProbe PCR proved to be a simple, rapid, and reliable method for the detection of macrolide-resistant isolates of Mycoplasma genitalium in a clinical setting.
Diversity exploiting MIMO-OFDMA ranging (2007)

This paper addresses initial ranging (uplink synchronization and power control) for TDD MIMO OFDMA systems. Exploiting the channel knowledge from the downlink control channel together with initial power control, we develop a novel initial ranging method which provides multiuser and multi-antenna diversity gains and significant power saving for the subscriber stations. By means of ranging signal design, we develop efficient low-complexity algorithms for OFDMA ranging. The advantages of the proposed approach over existing methods in terms of ranging performance, energy saving, and complexity saving are illustrated by analytical and simulation results.
Montelukast Attenuates Neuropathic Pain Through Inhibiting p38 Mitogen-Activated Protein Kinase and Nuclear Factor-Kappa B in a Rat Model of Chronic Constriction Injury (2014)

These results suggest that montelukast could effectively attenuate neuropathic pain in CCI rats by inhibiting the activation of p38MAPK and NF-κB signaling pathways in spinal microglia.
Effect of Surface Roughness on Paper Substrate Circuit Board (2012)

The European Union (EU) implemented the waste electrical and electronic equipment (WEEE) and restriction of hazardous substances (RoHS) directives in July 2006. To fulfil the environmental ethos of these EU directives, a printed circuit board (PCB) was developed based on a currently mass-manufactured board, but using a substrate of paper card, with interconnecting tracks added using conductive ink via a printing process. Components were bonded to the tracks using electrically conductive adhesives via an industry-based manufacturing line. During this investigation, paper card substrates of varying surface roughness were examined to establish the effect of substrate surface roughness for printing an interconnecting pattern for single-sided boards. Four degradable card substrate types with surface roughness values varying from 0.25 to 2.66 μm were trialled. The impact of substrate surface roughness on track resistance was investigated and a correlation between increased substrate roughness and a reduction in track resistance was established, a reduction in track resistance of up to 56% was observed. Flammability analysis of the substrates was performed in accordance with BS61189-2, while mechanical, electrical, and functional tests were undertaken inline with international standards. The developed PCBs were deemed to have met this established criteria, thus opening the possibility of producing a WEEE/RoHS-compliant environment-friendly PCB.
Lung ultrasound score as early predictor of bronchopulmonary dysplasia in very low birth weight infants (2019)

In VLBWI without BPD, LU score increases during the first week of life and decreases thereafter, whereas among subjects with BPD, the LU score remains high until 36 weeks´ PMA. LU score can predict the diagnosis of BPD at 1 week and 2 weeks of life, and may predict moderate-severe BPD at 4 weeks of life.
JNK targets p53 ubiquitination and degradation in nonstressed cells (1998)

In this study we elucidated the role of nonactive JNK in regulating p53 stability. The amount of p53-JNK complex was inversely correlated with p53 level. A peptide corresponding to the JNK binding site on p53 efficiently blocked ubiquitination of p53. Similarly, p53 lacking the JNK binding site exhibits a longer half-life than p53(wt). Outcompeting JNK association with p53 increased the level of p53, whereas overexpression of a phosphorylation mutant form of JNK inhibited p53 accumulation. JNK-p53 and Mdm2-p53 complexes were preferentially found in G0/G1 and S/G2M phases of the cell cycle, respectively. Altogether, these data indicate that JNK is an Mdm2-independent regulator of p53 stability in nonstressed cells.
Parallel Connection of 1200 V/100 A SiC MOSFET Half-bridge Modules (2015)

Silicon (Si) insulated-gate bipolar transistors (IGBTs) are widely used in power converters. Silicon carbide (SiC) technology will push the limits of switching devices in three directions: higher blocking voltage, higher operating temperature, and higher switching speed. The first SiC-metal-oxide-semiconductor field-effect transistor (MOSFET) half-bridge modules (SiC HBM) are now commercially available and look promising. Although they are still limited in breakdown voltage, these components should, for instance, improve traction-chain efficiencies. In particular, a significant reduction in switching losses is to be expected which should lead to improvements in power-to-weight ratios-of particular interest for rolling-stock. Nevertheless, because of the high switching speed and the high current levels required by traction applications, the implementation of these modules is critical. In this paper, the authors investigate the parallel connection of SiC HBM with a focus on traction equipment. The key points are underlined and an original approach is proposed to design the bus-bar and the gate-drive circuit. Experimental results performed on an opposition method test bench, valid the correct operation of three SiC modules in parallel.
Neutrophil Activation in Acute Renal Failure and Sepsis (1990)

Neutrophils are activated during sepsis. To find out whether granulocytes are further activated during hemodialysis with cellulosic and noncellulosic membranes, we compared the plasma levels of the main granulocyte components in patients with chronic uremia who were undergoing regular hemodialysis treatment and patients with acute renal failure with and without sepsis. During hemodialysis with cuprophane dialyzers, plasma-granulocyte elastase, in complex with alpha-proteinase inhibitor, and lactoferrin levels increased in patients who were undergoing regular hemodialysis treatment, but these levels increased further in patients with acute renal failure who did not have sepsis. Maximal neutrophil degranulation was observed in patients with acute renal failure and sepsis. There was only mild degranulation in all three groups during dialysis with dialyzers made of polysulfone. Our data demonstrate that neutrophil activation is increased in patients with acute renal failure, and it is increased further by superimposed sepsis. Cellulose-containing dialysis membranes introduce a further activation of neutrophils.
Gastric emptying and gastric myoelectrical activity in patients with diabetic gastroparesis: effect of long-term domperidone treatment. (1989)

We measured gastric emptying and gastric myoelectrical activity with solid-phase gastric-emptying tests and cutaneously recorded electrogastrograms (EGGs), respectively, in six insulin-dependent diabetic patients with nausea and vomiting who did not respond to standard treatments. Baseline solid phase gastric emptying was markedly delayed (78 +/- 8% retained at 120 min) and EGG recordings revealed gastric dysrhythmias; tachygastria (4-9 cpm signals) in one patient, 1- to 2-cpm waves in two patients, and flatline patterns in three patients. No patient had a normal 3-cpm EGG pattern. After 6 months of domperidone treatment, mean upper gastrointestinal symptoms scores decreased from 17.8 to 3.7 (p less than 0.01), and normal 3-cpm EGG frequencies were recorded from each of the six patients. The mean percentage of meal retained at 120 min decreased but did not improve significantly. Thus, establishment of normal 3-cpm gastric myoelectric activity and resolution of dysrhythmias, not normalization of emptying rates, was associated with improvement in upper gastrointestinal symptoms in these diabetic patients.
XVSAP1 from <i>Xerophyta viscosa</i> improves osmotic‐, salinity‐ and high‐temperature‐stress tolerance in Arabidopsis (2006)

XVSAP1, a gene isolated from a dehydrated Xerophyta viscosa cDNA library, was transformed into Arabidopsis thaliana by Ti plasmid-mediated transformation under the control of a cauliflower mosaic virus 35S promoter, a nos terminator and bar gene selection. Expression of XVSAP1 in Arabidopsis led to constitutive accumulation of the corresponding protein in the leaves. Transgenic Arabidopsis grown in tissue culture maintained higher growth rates during osmotic, high-salinity and high temperature stress, respectively. Non-transgenic plants had shorter roots, leaf expansion was inhibited and leaves were more chlorotic than those of the transgenic plants. This study demonstrates that XVSAP1 has a significant impact on dehydration, salinity and high-temperature stress tolerance in Arabidopsis.
Status of the National Ignition Facility: An optics perspective (2004)

The NIF is now operating the first four of its 192 independent laser beamlines. The design of the laser system is discussed from an optics perspective and the status of the optics manufacturing effort reviewed
Structure, chromosomal locus, and promoter analysis of the gene encoding the mouse helix-loop-helix factor HES-1. Negative autoregulation through the multiple N box elements. (1994)

HES-1 is a mammalian helix-loop-helix factor structurally related to the Drosophila hairy and Enhancer of split proteins. It binds more preferentially to the N box (CACNAG) than to the E box (CANNTG) and acts as a negative regulator. In this study, we have isolated and characterized the mouse HES-1 gene. This gene consists of four exons, and the positions of introns are well conserved when compared with those of the Drosophila hairy gene, except for the third intron. Southern blot and interspecies backcross analyses suggest that the mouse HES-1 gene is a single-copy gene and is located around position 26 on chromosome 16. The transcription initiation site, determined by the S1 nuclease and primer extension experiments, is located 31 nucleotides downstream of a TATA box. In the 5'-regulatory region, there are four N box sequences, and the DNase I foot-printing and gel mobility shift analyses show that HES-1 binds to these sequences. Transient transfection assays using C3H10T1/2 cells suggest that there are several positive regulatory regions in the HES-1 gene. However, cotransfection of the HES-1 expression vector leads to approximately 40-fold repression in promoter activity. Furthermore, when the N box sequences are disrupted, this negative regulation is severely impaired. These results raise the possibility that HES-1 gene expression may be negatively autoregulated through the N box sequences.
A voltage-controlled tunable thin-film distributed RC notch filter (2001)

Notch filters are widely used in communication and instrumentation systems not only for eliminating undesired frequencies and for measuring transient harmonic distortions, but also as central components of selective filters and oscillators in feedback arrangements. This paper describes the characteristics of a thin-film distributed RC (DRC) notch filter made from Au/TaN/Y-doped BaTiO/sub 3/ (Y-BT)/Pt. The dielectric (Y-BT) and resistive (TaN) films were grown by pulsed laser deposition (PLD). A notch frequency of 2.8 MHz and notch depth of -76.7 dB were measured from zero with a notch resistance (R/sub N/) of 34 /spl Omega/. The experimental optimum notch parameters of /spl alpha/=R/R/sub N/=19.7 and x/sub n/=/spl omega///spl omega//sub 0/=33.0 were obtained. Tunability of the notch frequency was observed with an applied DC bias voltage.
Effect of the revised AJCC staging (7th edition) on prognostic stratification in patients with surgically resected esophageal squamous cell carcinoma. (2013)

15 Background: Historically, the AJCC esophageal staging system separated patients into prognostic groups based on tumor, node, and metastasis (TNM) classifications. In 2010, the 7th edition (AJCC 7) significantly modified esophageal squamous cell cancer (ESCC) staging by separating ESCC from adenocarcinoma, incorporating tumor grade and location for node negative cancers, and stratifying by the number of involved regional nodes for node positive cancers. Our study aim was to determine whether AJCC 7 stage groupings provide improved survival prognostication compared to 6th edition (AJCC 6). Methods: We abstracted pathology and survival for 150 consecutive ESCC patients who underwent esophagectomy (1994-2012); 44 patients received induction therapy. AJCC 6 and AJCC 7 stages were assigned and overall survival analyzed from esophagectomy to death or most recent alive contact and censored at 60 months. Discriminatory ability and homogeneity within subgroups was assessed with Kaplan-Meier curves and monotonicity comparisons were evaluated with linear trend chi-squared tests. Overall survival was compared using Cox regression and Akaike Information Criterion (AIC) used to assess model fit. Results: Compared to AJCC 6, AJCC 7 upstaged 32 patients from IIa to IIb and 1 patient from IIb to IIIa and downstaged 3 patients from stage IIa to Ib. AJCC 7 subclassified 42 AJCC 6 stage III patients (17 IIIa, 10 IIIb and 15 IIIC). Median overall survival was 19 months. Kaplan-Meier log-rank statistic indicated stronger differentiation in AJCC 7 (19.8 vs 29.7). Cox regression likelihood (19.5 vs 26.1), AIC (618.1 vs 611.6), and linear trend chi-squared at 24- (17.5 vs 24.3) and 60-months (13.3 vs 17.3), were all superior for AJCC 7 stage groupings (AJCC 6 vs AJCC 7, respectively). Conclusions: AJCC 7 stage groupings demonstrate superior homogeneity, discriminatory ability and monotonicity compared to AJCC 6. Incorporating the extent of nodal disease, tumor location and tumor grade into the revised AJCC 7 stage classification improves prognostic stratification of surgically resected ESCC patients, including patients who received induction therapy.
Using Microwave Measurements to Detect Moisture in Asphaltic Concrete (1992)

Abstract An experimental technique based upon dielectric properties was developed to measure the volumetric moisture content in hot-mix asphalt concrete. The dielectric properties were calculated from the measured reflection coefficients and phase angles. The measurements were obtained over a band of frequencies in the microwave range of 12.4 to 18.0 GHz. The test program included different aggregate types, aggregate gradations, asphalt types, asphalt contents, air void contents, specimen thickness, and surface smoothness. Microwave reflection measurements were obtained for the hot-mix asphalt concrete specimens and their components in a sweep mode over the above frequency band. These measurements were analyzed, and the magnitude of the dielectric constant and the loss factor were calculated. The dielectric properties for these mixes were obtained at the dry state and at two levels of moisture content. The dielectric properties were correlated to the mix characteristics. Regression models were developed to predict the volumetric moisture content of hotmix asphalt concrete. A model developed from a theoretical approach was found to give the best correlation.
Herstellung wasserstoffdurchlässiger V-, Nb-und Ta-Folien mit Hilfe der UHV-Bedampfungstechnik / Preparation of Hydrogen Permeable Foils of V, Nb and Ta by Means of Ultra High Vacuum Techniques (1976)

Abstract A new sample preparation method for eliminating the hydrogen impermeable oxide surface layers of base metals like V, Nb and Ta is described. Applying UHV-techniques the metal foils are heated inductively and subsequently coated with a thin metallic Pd-film. By this method the metals are cleaned, at the same time annealed, and protected successfully against the formation of new passive layers, as is shown by x-rays, SIMS, and AES investigations.
Jointly Optimizing Diversity and Relevance in Neural Response Generation (2019)

Xiang Gao, Sungjin Lee, Yizhe Zhang, Chris Brockett, Michel Galley, Jianfeng Gao, Bill Dolan. Proceedings of the 2019 Conference of the North American Chapter of the Association for Computational Linguistics: Human Language Technologies, Volume 1 (Long and Short Papers). 2019.
Patterned neuronal attachment and outgrowth on surface modified, electrically charged fluoropolymer substrates (1994)

Fluorinated ethylenepropylene copolymer (FEP) and polyvinylidene fluoride (PVDF) can generate static and transient electrical charges, respectively, after bulk molecular rearrangements induced by electrical charging techniques. Neurons cultured on electrically active FEP and PVDF show increased levels of nerve fiber outgrowth compared to electrically neutral material. The purpose of the present study was to determine if the addition of charged surface groups to the surfaces of FEP and PVDF would modify the influence of bulk electrical charges on cultured neurons. Mouse neuroblastoma (Nb2a) cells were cultured on electrically charged and uncharged FEP and PVDF substrates with covalently modified surfaces containing hydroxyl (OH) and amine (NH2) groups. Surface chemical modification was performed on the entire surface or in discrete striped regions. Nb2a cells cultured on electrically active FEP and PVDF showed greater levels of differentiation than cells on electrically neutral substrates. The presence of NH2 groups attenuated these responses in serum-containing media. Cells attached to NH2 rich surfaces generally displayed a flatter morphology and tended to remain attached for longer time periods. Cells cultured on stripe-modified substrates in serum-containing media showed a strong preferential attachment to modified regions, especially on NH2 stripes. In summary, bulk electrical charges are more important than surface charges in stimulating Nb2a cell differentiation. Surface groups serve to modulate neuronal morphology and confer specific attachment promoting properties in serum-containing media. The development of an optimal neuronal regeneration template may require the incorporation of specific bulk and surface properties.