gebhart/patrepeval huggingface dataset:
Awarded Best Paper! -- Row-Diagonal Parity for Double Disk Failure Correction (2004)

Row-Diagonal Parity (RDP) is a new algorithm for protecting against double disk failures. It stores all data unencoded, and uses only exclusive-or operations to compute parity. RDP is provably optimal in computational complexity, both during construction and reconstruction. Like other algorithms, it is optimal in the amount of redundant information stored and accessed. RDP works within a single stripe of blocks of sizes normally used by file systems, databases and disk arrays. It can be utilized in a fixed (RAID-4) or rotated (RAID-5) parity placement style. It is possible to extend the algorithm to encompass multiple RAID-4 or RAID-5 disk arrays in a single RDP disk array. It is possible to add disks to an existing RDP array without recalculating parity or moving data. Implementation results show that RDP performance can be made nearly equal to single parity RAID-4 and RAID-5 performance.
Potential applications of an electron cyclotron resonance multicusp plasma source (1990)

An electron cyclotron resonance (ECR) multicusp plasmatron has been developed by feeding a multicusp bucket arc chamber with a compact ECR plasma source. This novel source produces large (about 25 cm diam), uniform (to within ±10%), dense (&gt;1011 cm−3) plasmas of argon, helium, hydrogen, and oxygen. It has been operated to produce an oxygen plasma for etching 12.7 cm (5 in.) positive photoresist-coated silicon wafers with uniformity within ±8%. Results and potential applications of this new ECR plasma source for plasma processing of thin films are discussed.
Molecular Mimicry by Cytomegaloviruses (1999)

Cytomegaloviruses (CMVs) are well known for their high prevalence rate within host populations as well as their ability to induce lifelong infections. To maintain a persistent and stable relationship with their host, CMVs have evolved various molecular mechanisms to both control host cell metabolism and evade immune surveillance. Among the viral gene products that are likely to be involved in these processes are homologues of cellular G protein-coupled receptors, MHC class I molecules and chemokines. The viral genes encoding these homologues have probably been pirated by the viruses during a long pathogen/host coevolution. In this report, we will discuss the possible functions of these homologues in the pathogenesis of CMV infections.
Social referral (2012)

Much work has been done to study the interplay between recommender systems and social networks. This creates a very powerful coupling in presenting highly relevant recommendations to the users. However, to our knowledge, little attention has been paid to leverage a user's social network to deliver these recommendations. We present a novel approach to aid delivery of recommendations using the recipient's friends or connections. Our contributions with this study are 1) A novel recommendation delivery paradigm called Social Referral, which utilizes a user's social network for the delivery of relevant content. 2) An implementation of the paradigm is described in a real industrial production setting of a large online professional network. 3) A study of the interaction between the trifecta of the recommender system, the trusted connections and the end consumer of the recommendation by comparing and contrasting the proposed approach's performance with the direct recommender system.
Bidirectional tracking using trajectory segment analysis (2005)

In this paper, we present a novel approach to keyframe-based tracking, called bi-directional tracking. Given two object templates in the beginning and ending keyframes, the bi-directional tracker outputs the MAP (maximum a posterior) solution of the whole state sequence of the target object in the Bayesian framework. First, a number of 3D trajectory segments of the object are extracted from the input video, using a novel trajectory segment analysis. Second, these disconnected trajectory segments due to occlusion are linked by a number of inferred occlusion segments. Last, the MAP solution is obtained by trajectory optimization in a coarse-to-fine manner. Experimental results show the robustness of our approach with respect to sudden motion, ambiguity, and short and long periods of occlusion.
Synthesis of Morpholino Monomers, Chlorophosphoramidate Monomers, and Solid‐Phase Synthesis of Short Morpholino Oligomers (2015)

Phosphorodiamidate morpholino oligomers (PMOs) are a highly capable class of synthetic antisense oligonucleotides that are used to study gene functions in in vitro and in vivo models. This unit describes the synthesis of exocyclic-amine-protected 7'-hydroxy and 7'-chlorophosphoramidate-activated morpholino monomers of A, T, G, and C, together with their incorporation into short PMO oligomers by solid-phase synthesis. Starting from ribonucleosides, the exocyclic-amine-protected 7'-hydroxy monomers are prepared following a modified Summerton protocol, which consists of a periodate cleavage/Schiff base formation/reduction cycle. The exocyclic amine protections are installed at a later stage (except G) to avoid the use of costly exocyclic-amine-protected counterparts that give control over protecting group manipulation. The 7'-hydroxy monomers with N-Trit/N-MMTr are then converted to the 7'-chlorophosphoramidate morpholino monomers in one step employing a combination of lithium bromide and DBU. These chlorophosphoramidate monomers are finally assembled by solid-support synthesis to obtain the short PMO oligomers.
Multicavity Magnetron With the “Rodded” Quasi-Metamaterial Cathode (2013)

We report on the use of the “rodded” or the longitudinally oriented metal-thin-wire structure as the explosive-emission cathode in high-power multicavity magnetrons. The rodded structure is transparent to the time-varying induced electric field <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex Notation="TeX">$E_{1}$</tex></formula> oscillating orthogonally to the individual rods or wires of the structure. The rods (wires) are longitudinally oriented, i.e., along the magnetron axis and parallel to the external dc axial magnetic field <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex Notation="TeX"> $H_{0}$</tex></formula> . The mode pattern established within the magnetron resonant cavity corresponds to one of the TE-like cavity modes of the magnetron operation. This allows defining the rodded structure as the quasi-metamaterial (i.e., not-entirely-metamaterial) structure. Particle-in-cell simulations of the U.S. Air Force Research Laboratory's six-cavity (AFRL-A6) L-band magnetron demonstrate that the rodded quasi-metamaterial cathode allows the magnetron to much more faster select the desired <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex Notation="TeX">$2 \pi/3$</tex></formula> magnetron operating mode within the broader range of the input operating parameters (from 130 to 200 kV at 0.15 T), as compared with the same magnetron working with the traditional smooth cylindrical cathode (from 140 to 160 kV at 0.15 T).
Discriminative Model Selection for Density Models. (2003)

Density models are a popular tool for building classifiers. When using density models to build a classifier, one typically learns a separate density model for each class of interest.
Immunological analysis of mucin molecules expressed by normal and malignant mammary epithelial cells (1987)

Many existing MAbs raised against the human milk fat globule or against carcinoma cells recognise epitopes on high-molecular-weight glycoproteins. In a comparative ELISA assay a number of these antibodies have been shown to react with an extract of the human milk fat globule. In comparative immunoblots of cultured normal milk cells and breast cell lines, all were found to bind to large molecules which show some variation in molecular weight depending on the cell source. The HMFG-2 antibody, which is widely used in cancer diagnosis, also recognises epitopes on lower-molecular-weight components. In T47D cells these may be as small as 80,000 Mr, and with electron microscopy this cell line can be shown to accumulate HMFG-2-reactive components in the Golgi apparatus. Using an HMFG-2 affinity column we have immunopurified HMFG-2-reactive material from the 2 breast cancer cell lines MCF-7 and T47D and shown that all of the above antibodies react in a solid-phase ELISA with the purified material. In addition to high-molecular-weight components, the immunopurified material was found to contain lower-molecular-weight components including a glycoprotein of 68,000 Mr that was not, however, recognised by the HMFG-2 antibody on a Western blot. We have used this immunopurified material to generate new MAbs. All of these recognise the high-molecular-weight bands seen with the other antibodies, but 2 of them also recognise a band at 68,000 Mr in blots of MCF-7 and T47D. The second-generation antibodies show a spectrum of reactivity on tissues similar to HMFG-2 and one reacts at least as strongly as HMFG-2 with methanol-acetone-fixed sections of breast cancers.
Spermaurin, an La1-like peptide from the venom of the scorpion<i>Scorpio maurus palmatus</i>, improves sperm motility and fertilization in different mammalian species (2016)

This work is part of the project 'LAB COM-14 LAB7 0004 01-LIPAV', funded by the program LabCom 2014 from the French Research Agency (ANR). Dr Arnoult reports grants from IMV Technologies during the conduct of the study. In addition, Drs Arnoult, Martinez, Ray and Schmitt have a patent EP16305642.7 pending containing some of the information presented in this manuscript.
DC link stabilized field oriented control of electric propulsion systems (1998)

Induction motor based electric propulsion systems can be used in a wide variety of applications including locomotives, hybrid electric vehicles, and ships. Field oriented control of these drives is attractive since it allows the torque to be tightly and nearly instantaneously controlled. However, such systems can be prone to negative impedance instability of the DC link. This paper examines this type of instability and sets forth a readily implemented albeit nonlinear control strategy to mitigate this potential problem.
ATRP of Amphiphilic Graft Copolymers Based on PVDF and Their Use as Membrane Additives (2002)

The direct preparation of amphiphilic graft copolymers from commercial poly(vinylidene fluoride) (PVDF) using atom transfer radical polymerization (ATRP) is demonstrated. Here, direct initiation of the secondary fluorinated site of PVDF facilitates grafting of the hydrophilic comonomer. Amphiphilic comb copolymer derivatives of PVDF having poly(methacrylic acid) side chains (PVDF-g-PMAA) and poly(oxyethylene methacrylate) side chains (PVDF-g-POEM) are prepared using this method. Surface segregation of PVDF-g-POEM additives in PVDF is examined as a route to wettable, foul-resistant surfaces on PVDF filtration membranes. Because of surface segregation during the standard immersion precipitation process for membrane fabrication, a PVDF/5 wt % PVDF-g-POEM membrane, having a bulk POEM concentration of 3.4 wt %, exhibits a near-surface POEM concentration of 42 wt % as measured by X-ray photoelectron spectroscopy (XPS). This membrane displays substantial resistance to BSA fouling compared with pure PVDF and wets spontaneously when placed in contact with water.
Non-naturally Occurring Regio Isomer of Lysophosphatidylserine Exhibits Potent Agonistic Activity toward G Protein-Coupled Receptors (2020)

Lysophosphatidylserine (LysoPS), an endogenous ligand of G protein-coupled receptors, consists of l-serine, glycerol, and fatty acid moieties connected by phosphodiester and ester linkages, respectively. An ester linkage of phosphatidylserine can be hydrolyzed at the 1-position or at the 2-position to give 2-acyl lysophospholipid or 1-acyl lysophospholipid, respectively. 2-Acyl lysophospholipid is in nonenzymatic equilibrium with 1-acyl lysophospholipid <i>in vivo</i>. On the other hand, 3-acyl lysophospholipid is not found, at least in mammals, raising the question of whether the reason for this might be that the 3-acyl isomer lacks the biological activities of the other isomers. Here, to test this idea, we designed and synthesized a series of new 3-acyl lysophospholipids. Structure-activity relationship studies of more than 100 "glycol surrogate" derivatives led to the identification of potent and selective agonists for LysoPS receptors GPR34 and P2Y10. Thus, the non-natural 3-acyl compounds are indeed active and appear to be biologically orthogonal with respect to the physiologically relevant 1- and 2-acyl lysophospholipids.
New Procedures For Preprocessing 0–1 Models With Knapsack-Like Constraints And Conjunctive And/Or Disjunctive Variable Upper Bounds (1991)

We present some preprocessing techniques for 0–1 models by taking advantage of the special structure provided by conjunctive and disjunctive variahle upper bounds, which are often used to express logical constraints. These new procedures include variable fixing, generation of clique and coverinduced inequalities, and coefficient reduction and related constraint generation procedures. By considering the information provided by the variable upper bound constraints, the procedures can be applied when the conditions required by the standard methods are not satisfied. Although some of our procedures require the solution of 0–1 problems arising from the original model, the subproblems (mainly, subset sum and set covering models) are usually small. In any case, our methodology can also be applied by using easily computed upper bounds on the optimal values of the subproblems.
Cross‐borehole electrical resistivity tomography (1990)

PreviousNext No AccessSEG Technical Program Expanded Abstracts 1990Cross‐borehole electrical resistivity tomographyAuthors: William D. DailyEarle OwenDouglas J. LaBrecqueWilliam D. DailyLawrence Livermore National Lab, Earle OwenLawrence Livermore National Lab, and Douglas J. LaBrecqueUniversity of Missouri, Rollahttps://doi.org/10.1190/1.1890267 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Permalink: https://doi.org/10.1190/1.1890267FiguresReferencesRelatedDetailsCited byHydro-frac monitoring using ground time-domain electromagnetics1 October 2015 | Geophysical Prospecting, Vol. 63, No. 6 SEG Technical Program Expanded Abstracts 1990ISSN (print):1052-3812 ISSN (online):1949-4645Copyright: 1990 Pages: 1779 publication data© 1990 Copyright © 1990 Society of Exploration GeophysicistsPublisher:Society of Exploration Geophysicists HistoryPublished Online: 10 Feb 2005 CITATION INFORMATION William D. Daily, Earle Owen, and Douglas J. LaBrecque, (1990), "Cross‐borehole electrical resistivity tomography," SEG Technical Program Expanded Abstracts : 573-574. https://doi.org/10.1190/1.1890267 Plain-Language Summary PDF DownloadLoading ...
Accurate BCJR-based synchronization algorithm for single carrier channels with extremely high order modulations (2016)

Microwave transmission is a predominant technology in telecommunication networks. As capacity requirement for mobile networks rises every day, microwave backhauls links are forced to constantly improve their spectral efficiency over limited allocated bandwidths. Moving toward higher order modulation is a cost-efficient solution to increase capacity in bandwidth-limited channels. Complex higher order modulations may be practical if a well-defined, high performance, carrier synchronization algorithm is provided to detect and remove the phase noise from the desired signal. The importance of such a precise carrier recovery algorithm is stressed with the transition from legacy, GaAs VCO frequency sources, to integrated, low-cost CMOS based VCOs that suffer from a significantly elevated phase noise level. Contribution of this paper is proposing a novel carrier synchronization algorithm that handles phase noise challenges effectively and allows complicated extremely high QAMs at an acceptable complexity level. Our proposed algorithm is pilot-aided and employs a BCJR-based sequence estimator to detect fast-varying phase noise symbol-by-symbol. We verify and validate performance of our proposed algorithm on VC707 XILINX board and emulation results confirm zero BER performance for complex modulation orders as high as 4K-QAM.
Self-Assembled LipidPolymer Hybrid Nanoparticles: A Robust Drug Delivery (2008)

We report the engineering of a novel lipidpolymer hybrid nanoparticle (NP) as a robust drug deliveryplatform,withhighdrugencapsulationyield,tunableandsustaineddrugreleaseprofile,excellentserum stability, and potential for differential targeting of cells or tissues. The NP comprises three distinct functional components: (i) a hydrophobic polymeric core where poorly water-soluble drugs can be encapsulated; (ii) a hydrophilicpolymericshellwithantibiofoulingpropertiestoenhanceNPstabilityandsystemiccirculationhalf-life; and (iii) a lipid monolayer at the interface of the core and the shell that acts as a molecular fence to promote drugretentioninsidethepolymericcore,therebyenhancingdrugencapsulationefficiency,increasingdrugloading yield, and controlling drug release. The NP is prepared by self-assembly through a single-step nanoprecipitation method in a reproducible and predictable manner, making it potentially suitable for scale-up.
New algorithms for parallelizing relational database joins in the presence of data skew (1994)

Parallel processing is an attractive option for relational database systems. As in any parallel environment however, load balancing is a critical issue which affects overall performance. Load balancing for one common database operation in particular, the join of two relations, can be severely hampered for conventional parallel algorithms, due to a natural phenomenon known as data skew. In a pair of recent papers (J. Wolf et al., 1993; 1993), we described two new join algorithms designed to address the data skew problem. We propose significant improvements to both algorithms, increasing their effectiveness while simultaneously decreasing their execution times. The paper then focuses on the comparative performance of the improved algorithms and their more conventional counterparts. The new algorithms outperform their more conventional counterparts in the presence of just about any skew at all, dramatically so in cases of high skew.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Poster (2019)

Distributed Reflected Denial of Service (DRDoS) attacks remain one of the most popular techniques to drain victim's network bandwidth. Despite the goal of disrupting network services of a particular victim, indirectly these attacks affect a large number of benign Internet citizens. In particular, the owners of services vulnerable to amplification have to waste their resources to process incoming requests. Moreover, the voluminous attack traffic generated as a result of the amplification lavishes Internet Service Provider (ISP) resources, bandwidth and money, causing Quality of Service (QoS) degradation and subscription fee increase for the customers. In this work we demonstrate a Software Defined Networking (SDN) based system to filter out garbage traffic from an ISP network. We employ a special type of a honeypot developed to collect information about ongoing DRDoS attacks. The firewall rules derived from this data are used to block incoming amplification requests from reaching amplifiers located within the provider network rescuing vulnerable services from being abused. In its turn, this prevents garbage traffic generation saving ISP's money and improving QoS.
SU‐C‐301‐03: A Spatially Distributed X‐Ray Source Array for High Resolution Digital Breast Tomosynthesis (2011)

Purpose: The current digital breast tomosynthesis (DBT) scanners are based on regular full‐field digital mammography systems and require partial isocentric motion of an x‐ray tube over certain angular range to record the projection views needed for reconstruction. This prolongs scanning time and degrades imaging quality due to motion blur. The purpose of this study is to evaluate the feasibility of improving spatial resolution and scanning speed of the current DBT device by replacing mammography tube with a stationary carbon nanotube (CNT) based x‐ray source array. Methods: A spatially distributed multi‐beam field emission x‐ray (MBFEX) source array was designed for DBT. Electrostatic simulations were carried out to design the electron focusing optics to achieve the desired x‐ray focal spot size. Finite element analysis was performed to determine the x‐ray source anode heat load. A control electronic system was developed to scan and to regulate the imaging dose from each beam by compensating the driving voltages and by modulating the exposure time from each beam. The x‐ray flux, lifetime, focal spot size, variation between different beams, etc were characterized. Results: A MBFEX source array with 31 individually controllable beams covering 30 degrees viewing angle was fabricated. It is operated up to 50KVp anode voltage and 30mA tube current per beam at an effective focal size comparable to that of the traditional mammography tube. Consistency in the beam‐to‐beam performance was achieved by optimizing the CNT cathodes and by electronic compensation. Tomosynthesis images of a breast phantom were obtained using the new source array. Conclusions: These preliminary results demonstrate the feasibility of CNT x‐ray source array for stationary DBT to eliminate image blurring from tube motion. With a fast detector the device can provide a higher spatial resolution at a reduced imaging time compared to the current rotating gantry DBT systems. This research is currently supported by the following grants&#65306;NCI Grant No. U54CA119343, NIH R01 Grant No. CA134598‐01 and the University Cancer Research Fund at the University of North Carolina. Dr. Xin Qian, was supported by a fellowship from DoD Grant No. BC087505.
Identification of a Specific Epitope of Haemophilus influenzae on a 16,600-Dalton Outer Membrane Protein (1985)

A mouse monoclonal antibody that recognizes an epitope on a 16,600-dalton outer membrane protein was developed to nontypable Haemophilus influenzae. This epitope was present on all 115 isolates of H. influenzae tested, including typable and nontypable strains. Screening of 89 strains of other bacteria demonstrated that this epitope is a highly specific marker for H. influenzae because the epitope was absent in virtually all other bacterial species tested. Western blot assays were performed with two normal human serum samples and convalescent-phase serum from an adult with bacteremia due to nontypable H. influenzae. Antibody to the 16,600-dalton outer membrane protein was present in all three human serum samples.