gebhart/patrepeval huggingface dataset:
DEEP LEARNING BASED INTELLIGENT METHODOLOGY FOR PHOTOVOLTAIC POWER QUALITY CONTROL WITH ENERGY STORAGE (2021)

Power imbalances instigated from Photovoltaics (PV) avert the incorporation of large-scale PV power into the grid and makes it a challenging resource as the intermittencies caused result in frequency variations and voltage interruptions which eventually engenders electricity blackouts. Furthermore, it compromises the associated battery's operation as it results in irregular battery charging/discharging. The fluctuating power also leads to the requirement of larger and impractical storage systems. Therefore, the power quality from the PV needs to be controlled to allow a stable output power supply to the load and also to enhance the operation of the connected Battery Energy Storage System (BESS). This paper presents a novel neural network (NN) model predictive control (MPC) method for PV power control and firming with BESS. Instead of creating a mathematical model of the plant for the prediction optimization step in an MPC, the proposed controller generates a NN plant model. Due to its innate characteristic, a NN model better captures the dynamics of the plant, delivers highly accurate predictions, and resolves the mathematical model complexity issues that occur in highly complicated plants. The proposed controller effectively firms the varying solar power and stabilizes the battery state of charge.
Targeted Glycoproteomic Identification of Biomarkers for Human Breast Carcinoma (2008)

Glycosylation is a dynamic post-translational modification that changes during the development and progression of various malignancies. During the oncogenesis of breast carcinoma, the glycosyltransferase known as N-acetylglucosaminyltransferase Va (GnT-Va) transcript levels and activity are increased due to activated oncogenic signaling pathways. Elevated GnT-V levels leads to increased beta(1,6)-branched N-linked glycan structures on glycoproteins that can be measured using a specific carbohydrate binding protein or lectin known as L-PHA. L-PHA does not bind to nondiseased breast epithelial cells, but during the progression to invasive carcinoma, cells show a progressive increase in L-PHA binding. We have developed a procedure for intact protein L-PHA-affinity enrichment, followed by nanospray ionization mass spectrometry (NSI-MS/MS), to identify potential biomarkers for breast carcinoma. We identified L-PHA reactive glycoproteins from matched normal (nondiseased) and malignant tissue isolated from patients with invasive ductal breast carcinoma. Comparison analysis of the data identified 34 proteins that were enriched by L-PHA fractionation in tumor relative to normal tissue for at least 2 cases of ductal invasive breast carcinoma. Of these 34 L-PHA tumor enriched proteins, 12 are common to all 4 matched cases analyzed. These results indicate that lectin enrichment strategies targeting a particular glycan change associated with malignancy can be an effective method of identifying potential biomarkers for breast carcinoma.
Proposal for distributed measurement of Müller matrix in optical fibers (2016)

We present a proposal for distributed measurement of Müller matrix with single-polarized probing light in the optical fiber. The physical principle and corresponding mathematical treatment on the propagation of Rayleigh backscattering light is investigated. Through numerical analysis, it can be demonstrated that the distribution of Müller matrix in the fiber can be acquired with the proposed method. This work may have significant potential in polarization-dependent distributed fiber-optic sensing.
Three-dimensional bioprinted biomimetic nanocomposite scaffolds for osteochondral regeneration (2014)

Due to the disparity in composition and mechanical properties of the osteochondral interface as well as the need for highly interconnected constructs, tissue engineering approaches for the regeneration of the osteochondral interface encounter unique challenges that are both biochemical and mechanical in nature. For this purpose, the current work has developed a novel biomimetic biphasic nanocomposite osteochondral scaffold. The system developed here has successfully integrated two biocompatible polymers each containing tissue-specific growth factor-encapsulated core-shell nanospheres. Specifically, a poly(caprolactone) based bone layer was successfully integrated with a poly(ethylene glycol) hydrogel cartilage layer. Development of a novel nanosphere fabrication technique for efficient growth factor encapsulation and sustained delivery via wet co-axial electrospray was employed for sustained growth factor delivery. Human bone marrow mesenchymal stem cell adhesion, osteogenic and chondrogenic differentiation were evaluated in our constructs and showed significantly improved hMSC adhesion and differentiation in vitro.
Adaptive integration of hardware and software lock elision techniques (2014)

Transactional Lock Elision (TLE) and optimistic software execution can both improve scalability of lock-based programs. The former uses hardware transactional memory (HTM) without requiring code changes; the latter involves modest code changes but does not require special hardware support. Numerous factors affect the choice of technique, including: critical section code, calling context, workload characteristics, and hardware support for synchronization.
Adaptive Power Level Setting of Femtocell Base Stations for Mitigating Interference with Macrocells (2010)

Femtocells are expected to increase network capacity, extend macrocell coverage, and introduce new services. Because femtocells share the same frequency band with macrocells in many cases, the femtocell base station (BS) must mitigate the interference with macrocells as well as ensure coverage in customer premises. However, conventional femtocell BS transmit power setting have not adequately accounted for the interference with neighboring macrocell mobile stations (MSs), leading to small femtocell user throughput. In this paper, we describe an adaptive femtocell BS transmit power level setting scheme to mitigate the interference with macrocell MSs. The proposed scheme estimates the path loss between the femtocell BS and the neighboring macrocell MSs on the basis of the received power levels from the neighboring macrocell MSs, thereby it mitigates the interference with macrocell MSs while maintaining good indoor coverage for femtocell MSs. According to the system level simulations of downlink LTE, femtocell user throughput of the proposed scheme at the edge of the macrocells is 36 % to 73 % greater than that of the conventional transmit power level setting scheme.
Development of the selective coagulation process. Final report (1992)

The selective hydrophobic coagulation (SHC) process is based on the recent finding that hydrophobic particles can be selectively coagulated without using traditional agglomerating agents or flocculants. The driving force for the coagulation is the attractive energy between hydrophobic surfaces, an interaction that has been overlooked in classical colloid chemistry. In most cases, selective separations can be achieved using simple pH control to disperse the mineral matter, followed by recovery of the coal coagula using techniques that take advantage of the size enlargement. In the present work, studies have been carried out to further investigate the fundamental mechanisms of the SHC process and the parameters that affect the process of separating coal from the ash-forming minerals and pyritic sulfur. Studies have included direct force measurements of the attractive interaction between model hydrophobic surfaces, in-situ measurements of the size distributions of coagula formed under a variety of operating conditions, and development of a population balance model to describe the coagulation process. An extended DLVO colloid stability model which includes a hydrophobic interaction energy term has also been developed to explain the findings obtained from the experimental studies. In addition to the fundamental studies, bench-scale process development test work has been performed to establish the best possible method of separating the coagula from dispersed mineral matter. Two types of separators, i.e., a sedimentation tank and a rotating drum screen, were examined in this study. The sedimentation tank proved to be the more efficient unit, achieving ash reductions as high as 60% in a single pass while recovering more than 90% of the combustible material. This device, which minimizes turbulence and coagula breakage, was used in subsequent test work to optimize design and operating parameters.
Nanodispersion of Polybutadiene in Polystyrene through Controlled “Grafting from” Free Radical Polymerization Using a Diphenylmethyl Type Radical (1998)

ADVERTISEMENT RETURN TO ISSUEPREVCommunication to the...Communication to the EditorNEXTNanodispersion of Polybutadiene in Polystyrene through Controlled “Grafting from” Free Radical Polymerization Using a Diphenylmethyl Type RadicalH. Maldonado-Textle, M. E. De León-Sáenz, J. L. Putaux, L. F. Ramos-De Valle, and R. Guerrero-SantosView Author Information Centro de Investigación en Química Aplicada, Blvd. Enrique Reyna 140, Saltillo Coahuila, 25100, México, and CERMAV-CNRS, BP 53, F-38041, Grenoble Cedex, France Cite this: Macromolecules 1998, 31, 8, 2697–2698Publication Date (Web):March 21, 1998Publication History Received29 October 1997Revised22 January 1998Published online21 March 1998Published inissue 1 April 1998https://doi.org/10.1021/ma971595uCopyright © 1998 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views136Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (78 KB) Get e-AlertsSUBJECTS:Aromatic compounds,Copolymers,Free radicals,Graft polymerization,Hydrocarbons Get e-Alerts
An architecture of high-performance frequency and phase synthesis (2000)

Frequency synthesis has many applications in today's commercial electronic and telecommunication system design. Some techniques exist which can be used to generate a frequency that is an integer or fractional multiple of a reference frequency. This architecture is used to generate a signal of any desired frequency in a certain range from multiple reference signals with same frequency but different phases. These reference signals may come from a voltage-controlled oscillator (VCO) which is close looped with a reference clock by a phase-lock loop (PLL). This architecture provides some unique features, superior quality, and ease of implementation. In some cases, the synthesized frequency is time-average frequency. The signal can be treated as a carrier signal frequency modulated by another signal. Various phase-shifted versions and duty cycle versions of this signal can also be generated from this architecture. This architecture also has direct application to spread spectrum clock generation.
Tyrosine phosphorylation of transcriptional coactivator WW‐domain binding protein 2 regulates estrogen receptor α function in breast cancer <i>via</i> the Wnt pathway (2011)

WW-binding protein 2 (WBP2) has been demonstrated in different studies to be a tyrosine kinase substrate, to activate estrogen receptor α (ERα)/progesterone receptor (PR) transcription, and to play a role in breast cancer. However, the role of WBP2 tyrosine phosphorylation in regulating ERα function and breast cancer biology is unknown. Here, we established WBP2 as a tyrosine phosphorylation target of estrogen signaling via EGFR crosstalk. Using dominant-negative, constitutively active mutants, RNAi, and pharmacological studies, we demonstrated that phosphorylation of WBP2 at Tyr192 and Tyr231 could be regulated by c-Src and c-Yes kinases. We further showed that abrogating WBP2 phosphorylation impaired >60% of ERα reporter activity, putatively by blocking nuclear entry of WBP2 and its interaction with ERα. Compared to vector control, overexpression of WBP2 and its phospho-mimic mutant in MCF7 cells resulted in larger tumors in mice, induced loss of cell-cell adhesion, and enhanced cell proliferation, anchorage-independent growth, migration, and invasion in both estrogen-dependent and -independent manners, events of which could be substantially abolished by overexpression of the phosphorylation-defective mutant. Hormone independence of cells expressing WBP2 phospho-mimic mutant was associated with heightened ERα and Wnt reporter activities. Wnt/β-catenin inhibitor FH535 blocked phospho-WBP2-mediated cancer cell growth more pronouncedly than tamoxifen and fulvestrant, in part by reducing the expression of ERα. Wnt pathway is likely to be a critical component in WBP2-mediated breast cancer biology.
Development of potent small-molecule inhibitors to drug the undruggable steroid receptor coactivator-3 (2016)

Protein-protein interactions (PPIs) play a central role in most biological processes, and therefore represent an important class of targets for therapeutic development. However, disrupting PPIs using small-molecule inhibitors (SMIs) is challenging and often deemed as "undruggable." We developed a cell-based functional assay for high-throughput screening to identify SMIs for steroid receptor coactivator-3 (SRC-3 or AIB1), a large and mostly unstructured nuclear protein. Without any SRC-3 structural information, we identified SI-2 as a highly promising SMI for SRC-3. SI-2 meets all of the criteria of Lipinski's rule [Lipinski et al. (2001) Adv Drug Deliv Rev 46(1-3):3-26] for a drug-like molecule and has a half-life of 1 h in a pharmacokinetics study and a reasonable oral availability in mice. As a SRC-3 SMI, SI-2 can selectively reduce the transcriptional activities and the protein concentrations of SRC-3 in cells through direct physical interactions with SRC-3, and selectively induce breast cancer cell death with IC50 values in the low nanomolar range (3-20 nM), but not affect normal cell viability. Furthermore, SI-2 can significantly inhibit primary tumor growth and reduce SRC-3 protein levels in a breast cancer mouse model. In a toxicology study, SI-2 caused minimal acute cardiotoxicity based on a hERG channel blocking assay and an unappreciable chronic toxicity to major organs based on histological analyses. We believe that this work could significantly improve breast cancer treatment through the development of "first-in-class" drugs that target oncogenic coactivators.
Intraoperative electrocorticography for physiological research in movement disorders: principles and experience in 200 cases (2016)

OBJECTIVE Contemporary theories of the pathophysiology of movement disorders emphasize abnormal oscillatory activity in basal ganglia-thalamocortical loops, but these have been studied in humans mainly using depth recordings. Recording from the surface of the cortex using electrocorticography (ECoG) provides a much higher amplitude signal than depth recordings, is less susceptible to deep brain stimulation (DBS) artifacts, and yields a surrogate measure of population spiking via "broadband gamma" (50-200 Hz) activity. Therefore, a technical approach to movement disorders surgery was developed that employs intraoperative ECoG as a research tool. METHODS One hundred eighty-eight patients undergoing DBS for the treatment of movement disorders were studied under an institutional review board-approved protocol. Through the standard bur hole exposure that is clinically indicated for DBS lead insertion, a strip electrode (6 or 28 contacts) was inserted to cover the primary motor or prefrontal cortical areas. Localization was confirmed by the reversal of the somatosensory evoked potential and intraoperative CT or 2D fluoroscopy. The ECoG potentials were recorded at rest and during a variety of tasks and analyzed offline in the frequency domain, focusing on activity between 3 and 200 Hz. Strips were removed prior to closure. Postoperative MRI was inspected for edema, signal change, or hematoma that could be related to the placement of the ECoG strip. RESULTS One hundred ninety-eight (99%) strips were successfully placed. Two ECoG placements were aborted due to resistance during the attempted passage of the electrode. Perioperative surgical complications occurred in 8 patients, including 5 hardware infections, 1 delayed chronic subdural hematoma requiring evacuation, 1 intraparenchymal hematoma, and 1 venous infarction distant from the site of the recording. None of these appeared to be directly related to the use of ECoG. CONCLUSIONS Intraoperative ECoG has long been used in neurosurgery for functional mapping and localization of seizure foci. As applied during DBS surgery, it has become an important research tool for understanding the brain networks in movement disorders and the mechanisms of therapeutic stimulation. In experienced hands, the technique appears to add minimal risk to surgery.
Sandwich Enzyme-Linked Immunosorbent Assay for the Detection of Bovine Blood in Animal Feed (2007)

Bovine; blood; monoclonal antibody; sandwich ELISA.
SPIRE1.03. Spatial Paradigm for Information Retrieval and Exploration (1995)

The SPIRE system consists of software for visual analysis of primarily text based information sources. This technology enables the content analysis of text documents without reading all the documents. It employs several algorithms for text and word proximity analysis. It identifies the key themes within the text documents. From this analysis, it projects the results onto a visual spatial proximity display (Galaxies or Themescape) where items (documents and/or themes) visually close to each other are known to have content which is close to each other. Innovative interaction techniques then allow for dynamic visual analysis of large text based information spaces.
Ferroelectric Oxide Memory FET (FEMFET) Development (1994)

This Final Technical Report covers the integration of oxide ferroelectric thin films (e.g. bismuth titanate = Bi4Ti3Ol2 = BTO or lead zirconate titanate = PZT) into the gate dielectric of a metal-insulator-silicon field effect transistor (MISFET), capable of functioning in a non-volatile, non- destructive readout (NDRO) ferroelectric random access memory (FERRAM). Also provided is a detailed description of the test vehicles implemented for the study of fabrication process integration and optimization and the resultant properties of ferroelectric/(semiconductor) memory FET (FEMFET) and related structures. The Interim Report covering the first phase of this contract described an investigation of UHV-deposited ferroelectric fluoride (BaMgF4 = BMF) films as gate insulators; however, BMF transistor structures exhibited rather poor reproducibility, and electrical instability manifested as poor retention capability. Results of the second phase of this program are presented in this report, which focuses on exploration of oxide ferroelectric films for the FEMFET gate dielectric. There is growing evidence that layers of ferroelectric oxides, when suitably processed may possess switching and stability properties that are far superior to those attainable with BMF layers.
17.1: <i>Invited Paper:</i> Improvement of Lifetime in Organic Electroluminescence (2004)

Abstract Excellent organic electroluminescent materials are needed to realize EL devices with high performance. We have succeeded in realizing bright and efficient devices with long lifetime in blue color region by the use of a new host material. The lifetime was estimated to be 21000 hr (@1000 cd/m 2 ) for the light blue devices. Furthermore, we achieved the long lifetime of 40000 hr (@1000 cd/m 2 ) in green region.
Spatial analysis of discrete plenoptic sampling (2011)

Plenoptic cameras are intended to fully capture the light rays in a scene. Using this information, optical elements can be applied to a scene computationally rather than physically-allowing an infinite variety of pictures to be rendered after the fact from the same plenoptic data. Practical plenoptic cameras necessarily capture discrete samples of the plenoptic function, which together with the overall camera design, can constrain the variety and quality of rendered images. In this paper we specifically analyze the nature of the discrete data that plenoptic cameras capture, in a manner that unifies the traditional and focused plenoptic camera designs. We use the optical properties of plenoptic cameras to derive the geometry of discrete plenoptic function capture. Based on this geometry, we derive expressions for expected resolution from a captured plenoptic function. Our analysis allows us to define the "focused plenoptic condition," a necessary condition in the optical design that distinguishes the traditional plenoptic camera from the focused plenoptic camera.
Oxygent™; A Novel Probe of Tissue Oxygen Tension (1992)

We have examined the 19F NMR spectrum and relaxation behavior of Oxygent (an emulsion of perfluorooctylbromide). Each of the resonances exhibits a linear relationship between spin-lattice relaxation rate and oxygen tension at constant temperature. Oxygent provides enhanced sensitivity to changes in oxygen tension compared with other emulsions used previously. We have used Oxygent to determine the oxygen tension in the liver of a mouse.
Automated phase-measuring profilometry: a phase mapping approach (1985)

When a sinusoidal grating is projected on either a reference plane or a diffuse object to be measured, every point along a line normal to the grating lines, on the reference plane as well as the object, can be characterized by a unique phase value. By measuring this phase accurately using phase modulation methods and by determining points on the reference plane and the object having identical phases, it is shown that the object height can be computed. A working system requires a projector, a translatable sinusoidal grating, and a detector array interfaced to a microcomputer. Results of measurements on diffuse test objects are described and errors are analyzed.