gebhart/patrepeval huggingface dataset:
Coupled Interfacial Tension and Phase Behavior Model Based on Micellar Curvatures (2017)

This article introduces a consistent and robust model that predicts interfacial tensions for all microemulsion Winsor types and overall compositions. The model incorporates film bending arguments and Huh's equation and is coupled to phase behavior so that simultaneous tuning of both interfacial tension (IFT) and phase behavior is possible. The oil-water interfacial tension and characteristic length are shown to be related to each other through the hydrophilic-lipophilic deviation (HLD). The phase behavior is tied to the micelle curvatures, without the need for using the net average curvature (NAC). The interfacial tension model is related to solubilization ratios in order to introduce a coupled interfacial tension-phase behavior model for all phase environments. The approach predicts two- and three-phase interfacial tensions and phase behavior (i.e., tie lines and tie triangles) for changes in composition and HLD input parameters, such as temperature, pressure, surfactant structure, and oil equivalent alkane carbon number. Comparisons to experimental data show excellent fits and predictive capability.
Switching control for constrained wave energy converters (2017)

This paper addresses the problem of designing a control that maximizes the harvested energy of a wave energy converter, in the presence of displacement constraints. The feasible displacement range is split into two segments. In the first segment (the inner segment), an unconstrained optimal control is used. In the outer segment, a constraint control is used. For the unconstraint control in the inner segment, a singular arc control is implemented which is proved to maximize the harvested energy when there are no constraints. In the outer segment, two methods for constrained control are investigated and compared. The first method is a linear quadratic control that penalizes the displacement along with maximizing the harvested energy. The second method implements a nonlinear damping control that forces higher damping for higher displacement. Both concepts are compared to a linear quadratic control that penalizes the displacement over the whole displacement range. Numerical simulations are conducted and results demonstrate the superiority of the switching control concept when irregular waves are simulated.
Extracting Parallel Sentences from Comparable Corpora using Document Level Alignment (2010)

The quality of a statistical machine translation (SMT) system is heavily dependent upon the amount of parallel sentences used in training. In recent years, there have been several approaches developed for obtaining parallel sentences from non-parallel, or comparable data, such as news articles published within the same time period (Munteanu and Marcu, 2005), or web pages with a similar structure (Resnik and Smith, 2003). One resource not yet thoroughly explored is Wikipedia, an online encyclopedia containing linked articles in many languages. We advance the state of the art in parallel sentence extraction by modeling the document level alignment, motivated by the observation that parallel sentence pairs are often found in close proximity. We also include features which make use of the additional annotation given by Wikipedia, and features using an automatically induced lexicon model. Results for both accuracy in sentence extraction and downstream improvement in an SMT system are presented. 1
Autoantibodies to citrullinated proteins: ACPA (2005)

Anti-perinuclear factor and anti-keratin antibodies have long been known to be specifically associated with rheumatoid arthritis (RA). They were first demonstrated to target various forms of (pro)filaggrin, a protein of stratified epithelia. Then, they were found to belong to a single family of autoantibodies targeting proteins that bear peptidic epitopes centered by a citrullyl residue: the anti-citrullinated protein autoantibodies (ACPA). The main targets of ACPA in the synovial tissue were demonstrated to be citrullinated forms of the a- and beta-chains of fibrin. A chronic conflict between locally produced ACPA and deposits of citrullinated fibrin is probably responsible for self-maintaining of RA synovial inflammation. Various tests for the detection of ACPA have been developed: recent ELISAs confirm their high diagnostic specificity and improve their diagnostic sensitivity. Since ACPA appear very early in the course of the disease, their detection is of major interest to identify RA among recent arthritides. Moreover, their prognostic value may lead to start early 'aggressive' treatments to prevent irreversible joint damage.
High-speed germanium-on-insulator photodetectors (2005)

We will present recent results from our work on germanium-on-silicon photodetectors. We demonstrate that the devices display high bandwidth and efficiency at 850 nm, and could be suitable for future 40 Gb/sec optical interconnect applications.
Fourier Transform Light Scattering of Inhomogeneous and Dynamic Structures (2008)

Fourier transform light scattering (FTLS) is a novel experimental approach that combines optical microscopy, holography, and light scattering for studying inhomogeneous and dynamic media. In FTLS the optical phase and amplitude of a coherent image field are quantified and propagated numerically to the scattering plane. Because it detects all the scattered angles (spatial frequencies) simultaneously in each point of the image, FTLS can be regarded as the spatial equivalent of Fourier transform infrared spectroscopy, where all the temporal frequencies are detected at each moment in time.
Matrix-addressable electrochromic display cell (1981)

We report an electrochromic display cell with intrinsic matrix addressability. The cell, based on a sputtered iridium oxide film (SIROF) and a tantalum-oxide hysteretic counterelectrode, has electrochromic parameters (i.e., response times, operating voltages, and contrast) similar to those of other SIROF display devices, but in addition, has short-circuit memory and voltage threshold. Memory and threshold are sufficiently large to allow, in principle, multiplexing of electrochromic display panels of large-screen TV pixel size.
A Favorable Clinical Trend Is Associated With CD8 T-Cell Immune Responses to the Human Papillomavirus Type 16 E6 Antigens in Women Being Studied for Abnormal Pap Smear Results (2010)

The CD8 T-cell immune responses to the HPV-16 E6 antigens but not to E7 antigens are associated with a favorable clinical trend regardless of HPV types currently detected.
NOVEL ZEROTH-ORDER RESONANCE IN COMPOSITE RIGHT/LEFT- HANDED TRANSMISSION LINE RESONATORS (2003)

White blood cell (WBC) count is considered a prognostic risk factor in acute myeloid leukemia. As density of leukemic cells increases, the cytotoxic activity of certain anticancer drugs, such as vincristine and doxorubicin, progressively decreases. In this study, we investigated the cell density-dependent induction of apoptosis of human acute myeloid leukemia U937 and ML-1 cells by disulfiram (DSF), the dithiocarbamate drug recently proposed for treatment of human cancers. This effect is dependent on uptake of extracellular copper and its intracellular accumulation. High-density cells cannot uptake and accumulate this metal to a sufficient level that would allow induction of apoptosis due to progressive decrease of its extracellular concentration. Simple addition of copper can resume sensitivity of high-density leukemic cells to DSF and improve efficiency of anti-leukemic therapies using this drug, thus providing benefit to patients with high WBC count.
Disc Related Cytokines Inhibit Axonal Outgrowth From Dorsal Root Ganglion Cells In Vitro (2005)

It was evident that the 2 studied cytokines inhibited the outgrowth of axons from cultured DRG cells, thus suggesting a neurotoxic potential. However, the inhibition was not as pronounced as for nucleus pulposus. These data may increase our understanding for cytokine induced nerve injury, with implications for future treatment strategies for such conditions.
Harmonia: A globally coordinated garbage collector for arrays of Solid-State Drives (2011)

Solid-State Drives (SSDs) offer significant performance improvements over hard disk drives (HDD) on a number of workloads. The frequency of garbage collection (GC) activity is directly correlated with the pattern, frequency, and volume of write requests, and scheduling of GC is controlled by logic internal to the SSD. SSDs can exhibit significant performance degradations when garbage collection (GC) conflicts with an ongoing I/O request stream. When using SSDs in a RAID array, the lack of coordination of the local GC processes amplifies these performance degradations. No RAID controller or SSD available today has the technology to overcome this limitation. This paper presents Harmonia, a Global Garbage Collection (GGC) mechanism to improve response times and reduce performance variability for a RAID array of SSDs. Our proposal includes a high-level design of SSD-aware RAID controller and GGC-capable SSD devices, as well as algorithms to coordinate the global GC cycles. Our simulations show that this design improves response time and reduces performance variability for a wide variety of enterprise workloads. For bursty, write dominant workloads response time was improved by 69% while performance variability was reduced by 71%.
Data from A Group of Genome-Based Biomarkers That Add to a Kattan Nomogram for Predicting Progression in Men with High-Risk Prostate Cancer (2023)

<div>Abstract<p><b>Purpose:</b> The three main treatment options for primary prostate cancer are surgery, radiation, and active surveillance. Surgical and radiation intervention for prostate cancer can be associated with significant morbidity. Therefore, accurate stratification predictive of outcome for prostate cancer patients is essential for appropriate treatment decisions. Nomograms that use clinical and pathologic variables are often used for risk prediction. Favorable outcomes exist even among men classified by nomograms as being at high risk of recurrence.</p><p><b>Experimental Design:</b> Previously, we identified a set of DNA-based biomarkers termed Genomic Evaluators of Metastatic Prostate Cancer (GEMCaP) and have shown that they can predict risk of recurrence with 80% accuracy. Here, we examined the risk prediction ability of GEMCaP in a high-risk cohort and compared it to a Kattan nomogram.</p><p><b>Results:</b> We determined that the GEMCaP genotype alone is comparable with the nomogram, and that for a subset of cases with negative lymph nodes improves upon it.</p><p><b>Conclusion:</b> Thus, GEMCaP shows promise for predicting unfavorable outcomes for negative lymph node high-risk cases, where the nomogram falls short, and suggests that addition of GEMCaP to nomograms may be warranted. Clin Cancer Res; 16(1); 195–202</p></div>
Integrated Services Provisioning Across Cryptographic Boundaries (2006)

IntServ resource reservation protocol (RSVP) is based on end-to-end signaling and the current HAIPE specification does not allow for RSVP signaling to be bypassed across cryptographic boundaries. Since end-to-end RVSP signaling traffic is not bypassed across HAIPE boundaries, it does not seamlessly allow for IntServ based QoS provisioning within the core Black network. This leads us to the challenge of defining a mechanism by which IntServ/RSVP can be supported within the core Black network. We built upon our prior work on a dynamic diffserv network QoS management framework developing an IntServ implementation that operates across HAIPE boundary. The objective of our effort was to allow for individual IntServ/RSVP sessions in the red security enclave to be aggregated into a finite set of dynamically instantiated IntServ/RSVP sessions between ingress and egress nodes within the black security enclave. We used simple policy based management whereby the RSVP daemon on the ingress black node monitors the DSCP values on its outbound ports to initiate the creation or deletion of aggregated IntServ/RSVP sessions to the appropriate egress black node. These egress black node sessions are dynamically resized based on traffic demand and network state. This approach allowed for end-to-end IntServ across HAIPE boundaries
The sequence of the Mycoplasma arthritidis superantigen, MAM: identification of functional domains and comparison with microbial superantigens and plant lectin mitogens. (1996)

Mycoplasma arthritidis, an agent of chronic proliferative arthritis of rodents, secretes a potent soluble superantigen, MAM, that is active for both murine and human T and B lymphocytes. We now report the complete nucleotide and amino acid sequence of MAM and show it to be distinct from other proteins and not closely related phylogenetically to other superantigens. Two functional domains on MAM are identified based on the ability of peptides encompassing these regions to inhibit lymphocyte proliferation by the intact MAM molecule. One of these domains shares short sequences or epitopes with other microbial superantigens. The second domain contains the consensus legume lectin motif-beta, which is important for T cell activation by concanavalin (Con) A. MAM and Con A peptides containing this motif are functionally cross reactive, suggesting a novel secondary pathway for T cell activation by MAM.
Special Issue on Nonlinear-Optic Waveguide Materials and Devices. Mach-Zehnder Type All-Optical Switch with a GaAs Waveguide. (1993)

All-optical switches are attractive for future optical communication and data processing.
Zebroid (2009)

P2P file transfers and streaming have already seen a tremendous growth in Internet applications. With the rapid growth of IPTV, the need to efficiently disseminate large volumes of Video-on-Demand (VoD) content has prompted IPTV service providers to consider peer-assisted VoD content delivery. This paper describes Zebroid, a VoD solution that uses IPTV operational data on an on-going basis to determine how to pre-position popular contents in customer set-top boxes during idle hours to allow these peers to assist the VoD server in content delivery during peak hours. Latest VoD request distribution, set-top box availability, and capacity data on network components are all taken into consideration in determining the parameters used in the striping algorithm of Zebroid. We show both by simulation and emulation on a realistic IPTV testbed that the VoD server load can be significantly reduced by more than 50-80% during peak hours by using Zebroid.
Molecular self-assembly approaches to multilayer organic light-emitting-diode structures (1998)

An attractive and challenging approach to the construction of robust, structurally precise thin film materials with large second-order optical nonlinearities or electroluminescent characteristics is the covalent self-assembly of arrays of tailored molecular building blocks. In this contribution, we discuss the implementation of self-limiting siloxane self- assembly processes to achieve the fabrication of structurally regular organic LED (OLED) devices. Areas surveyed include: (1) the use of layer-by-layer self-assembly for ITO electrode modification/passivation/hole-electron carrier balancing in vapor deposited devices, (2) the synthesis of chlorosilane- functionalized precursor molecules for hole transport (HTL), emissive layer (EML), and electron transport layer (ETL) self- assembly, (3) the physicochemical and microstructural characterization of the HTL self-assembly process employing a triarylamine precursor, (4) the fabrication and characterization of a hybrid self-assembled + vapor deposited two-layer OLED, (5) the fabrication and characterization of a fully self-assembled two-layer OLED.
A New Life for an Old Reagent: Fluoroalkyl Amino Reagents as Efficient Tools for the Synthesis of Diversely Fluorinated Pyrazoles (2013)

Abstract Herein we describe the first practical method for the regioselective preparation of 3,5‐bis(fluoroalkyl)pyrazoles. Starting from commercially available fluoroacetoacetates and by using (tetrafluoroethyl)dimethylamine as a convenient CF 2 H transfer reagent, this straightforward one‐pot sequence affords highly substituted pyrazoles in good yields and excellent regioselectivity. Furthermore, these carboxylate intermediates were converted into the corresponding pyrazolic acids, which are valuable building blocks for the design of novel bioactive ingredients.
The Use of near Infrared Reflectance Spectroscopy to Predict the Insoluble Dietary Fibre Fraction of Cereal Products (1998)

The insoluble and soluble fractions of dietary fibre have different human physiological effects and their presence in foods is of interest to consumers, the medical community and the cereal product industry. The development of a model, using near infrared (NIR) reflectance spectroscopy, to predict insoluble dietary fibre in a wide range of dry-milled cereal products and grains is described. The products included breakfast cereals, crackers, brans, pastas and flours. Insoluble dietary fibre was measured by the AOAC enzymatic–gravimetric procedure (AOAC 991.43). The range in insoluble dietary fibre was 0–48%. Near infrared reflectance spectra were obtained with a scanning monochromator and data analysed with a commercial analysis program. A calibration ( n = 90) was developed for prediction of insoluble dietary fibre using preprocessed spectra and modified partial least squares regression. The standard error of cross validation and R 2 were 1.34% and 0.99, respectively. The model was tested with independent validation samples ( n = 32) and the resulting standard error of performance and r 2 were 1.13% insoluble dietary fibre and 0.99, respectively. The results show that NIR spectroscopy can be used to predict the insoluble dietary fibre content in a wide variety of processed and unprocessed cereal products.
High‐Throughput Proteomics Enabled by a Photocleavable Surfactant (2020)

Mass spectrometry (MS)-based proteomics provides unprecedented opportunities for understanding the structure and function of proteins in complex biological systems; however, protein solubility and sample preparation before MS remain a bottleneck preventing high-throughput proteomics. Herein, we report a high-throughput bottom-up proteomic method enabled by a newly developed MS-compatible photocleavable surfactant, 4-hexylphenylazosulfonate (Azo) that facilitates robust protein extraction, rapid enzymatic digestion (30 min compared to overnight), and subsequent MS-analysis following UV degradation. Moreover, we developed an Azo-aided bottom-up method for analysis of integral membrane proteins, which are key drug targets and are generally underrepresented in global proteomic studies. Furthermore, we demonstrated the ability of Azo to serve as an "all-in-one" MS-compatible surfactant for both top-down and bottom-up proteomics, with streamlined workflows for high-throughput proteomics amenable to clinical applications.
Double cohesion in structural DNA nanotechnology (2006)

Double cohesion has proved to be a useful tool to assemble robust 2D arrays of large tiles. Here we present a variety of examples showing the utility of this approach. We apply this principle to the 3 types of 2D lattice sections of arrays whose individual tiles are inherently 3 dimensional, because they contain three vectors that span 3-space. This application includes motifs which are based on the tensegrity triangle, the six-helix bundle motif and on three skewed triple crossover molecules. All of these designs have the potential to form 3 dimensional structures if all three directions of propagation are allowed. If one direction is blunted, 2D arrays form, and all 3 combinations are presented here. In addition, a large parallelogram array that was not attainable previously using single duplex cohesion was also constructed using double cohesion. For comparison, arrays which use another type of double cohesion, double paranemic (PX) cohesion are also presented. Double cohesion of sticky ends proved to be the more effective tool to assemble large motifs into arrays.
95 GHz helical TWT design (2009)

The helical slow-wave circuit is an attractive choice for traveling wave tube amplifiers (TWTAs) because of its inherently large bandwidth and relatively high RF efficiency. Unfortunately, as the operational frequency increases beyond Q-or V-band, its use has been limited by conventional fabrication techniques, and by the difficulty of passing enough current through the center of such a small structure. This paper describes the design and fabrication status of a 95 GHz TWT using microfabrication technology to create and assemble the helix. The electron beam propagates as two kidney shaped beamlets between the helix outer diameter and barrel.
Design and <i>in situ</i> synthesis of hierarchical SAPO-34@kaolin composites as catalysts for methanol to olefins (2019)

An <italic>in situ</italic> synthesis strategy to fabricate SAPO-34@kaolin composites from kaolin microspheres as catalysts for methanol to olefins is developed.
Photochemical generation of superoxide radicals in aqueous solutions (1978)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPhotochemical generation of superoxide radicals in aqueous solutionsRichard A. Holroyd and Benon H. J. BielskiCite this: J. Am. Chem. Soc. 1978, 100, 18, 5796–5800Publication Date (Print):August 1, 1978Publication History Published online1 May 2002Published inissue 1 August 1978https://pubs.acs.org/doi/10.1021/ja00486a034https://doi.org/10.1021/ja00486a034research-articleACS PublicationsRequest reuse permissionsArticle Views404Altmetric-Citations47LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A speckle target adaptive imaging technique in the presence of distributed aberrations (1997)

Acoustic velocity inhomogeneities in tissue result in aberration of ultrasound images. These aberrations can be modeled as a near field thin phase screen or as a distributed aberrator. The effect of a near field thin phase screen is to time shift the received echo at each element, while distributed aberrators result in both pulse distortions and time shifts from element to element. Most current techniques for the correction of distributed aberrators are limited to application on point targets. A new technique is proposed which uses multiple transmits from spatially shifted transmit apertures (the translating transmit aperture algorithm), in conjunction with phase conjugate filters, to correct for distributed aberrations in the presence of speckle targets. The performance of the translating transmit aperture algorithm in improving the correlation between signals received by elements of different spatial separations is measured, and factors affecting the performance of this technique are investigated in simulation and experiment.