gebhart/patrepeval huggingface dataset:
Newcomer Information Seeking: Individual and Contextual Influences (1997)

This study examined situational and individual influences on the proactive information seeking of newcomers. Task interdependence was expected to be positively related to information seeking, given that it links newcomers to organizational insiders. Newcomers' work related self‐efficacy and the physical accessibility of organizational insiders were both predicted to moderate the relationship between task interdependence and information seeking. Usable surveys were completed by 421 co‐op students (295 males and 126 females) who had been participating in career‐relevant internships for approximately 4.5 weeks. All students were enrolled in an educational programme that rotates students between twelve weeks in class and twelve weeks on internship over a period of five years. Controlling for the number of previous internships and size of work group, results supported the joint moderating effect, with newcomers low on self‐efficacy exhibiting greater information seeking when task interdependence and accessibility were high. Applied implications of the results and directions for future research on proactive information seeking and socialization are discussed.
Engineered Lactic Acid Bacterium <i>Lactococcus lactis</i> Capable of Binding Antibodies and Tumor Necrosis Factor Alpha (2010)

We have optimized the display of the B domain of staphylococcal protein A on the surface of Lactococcus lactis. The maximum binding capacity was estimated at 0.146 μg of antibody per 10⁸ cells and was sustained at 86% after treatment with simulated gastric juice. A tumor necrosis factor alpha (TNF-α)-binding affibody was also displayed and bound TNF-α, which could be useful in the treatment of inflammatory bowel disease.
An Unprecedented Approach to 4,5-Disubstituted Pyrimidine Derivatives by a ZnCl<sub>2</sub>-Catalyzed Three-Component Coupling Reaction (2009)

We have developed a ZnCl(2)-catalyzed three-component coupling reaction involving a variety of functionalized enamines, triethyl orthoformate, and ammonium acetate, which leads to the production of 4,5-disubstituted pyrimidine derivatives in a single step. The procedure can be successfully applied to the efficient synthesis of mono- and disubstituted pyrimidine derivatives, using methyl ketone derivatives instead of enamines.
Mesomorphic 4-Alkylphenyl 4-Benzoyloxybenzoate Bearing a Terminal Vinyl Group (1979)

Abstract 4-Alkylphenyl 4-(4-vinyl-, methacryloyloxy-, and methacrylamido-benzoyloxy)benzoates have been synthesized by the reactions of 4-alkylphenyl 4-hydroxybenzoates with the corresponding substituted benzoyl chloride in pyridine. The mesomorphic ranges of these novel monomers are highly dependent upon the type of substituent at both ends of the molecules.
A saturated red color converter for visible light communication using a blend of star-shaped organic semiconductors (2017)

We report a study of blends of semiconducting polymers as saturated red color converters to replace commercial phosphors in hybrid Light emitting diodes (LEDs) for visible light communication (VLC). By blending two star-shaped organic semiconductor molecules, we found a near complete energy transfer (&gt;90% efficiency) from the green-emitting truxene-cored compound T4BT-B to the red-emitting boron dipyrromethene (BODIPY) cored materials. Furthermore, we have demonstrated the capability of these materials as fast color converters for VLC by measuring their intrinsic optical modulation bandwidth and data rate. The measured 3 dB modulation bandwidth of blends (∼55 MHz) is more than 10 times higher than commercially available LED phosphors and also higher than the red-emitting BODIPY color converter alone in solution. The data rate achieved with this blend is 20 times higher than measured with a commercially available phosphor based color converter.
Using disulfide oil as coke inhibitor to reduce environmental hazards in olefin heaters (2018)

<span class="CharAttribute40"><span>This paper describes the feasibility of replacing a sulfur-based additive with the waste by-product disulfide oil (DSO) in steam cracking for the production of olefin. The objective of adding this substance is to reduce coke formation, and consequently, prevent its formation on the inner walls of the reactor and heat exchanger. It is reported that dimethyl sulfide (DMDS) is a source of hydrogen sulfide, and it is hydrogen sulfide that minimizes coke formation, even though the mechanism is not clear. Disulfide oil is a waste material in gas refineries and a source for hydrogen sulfide production; therefore, it makes sense to evaluate its efficacy in minimizing CO production and coke formation during olefin production. Therefore, pilot plant runs were performed to evaluate its feasibility. By using disulfide oil, the total sulfur content of the pyrolysis gasoline will change and be equal to 26.89 mg/L for the unit with a capacity production of 18000 kg/hr. This action not only provides a low-price resource that inhibits coke deposition in olefin plants but also curtails the emission of hydrogen sulfide into the environment.</span></span>
Elevated serum ferritin level effectively discriminates severity illness and predicts prognosis of COVID-19 patients (2020)

<title>Abstract</title> During coronavirus disease 2019 (COVID-19) pandemic, medical resources in every country is in shortage. Efficacious indicators of discriminating severe illness and predicting outcome is in urgent need. We collected data and clinical records from 79 COVID-19 patients admitted between January 12, 2020 and February 21, 2020 at Wuhan Union hospital, China. Spearman’s correlation analysis, receiver operating characteristic (ROC) curve, logistic regression model, and Kaplan-Meier survival curves were employed in the analysis. Of 79 patients enrolled, 2 died in hospital, 8 were transferred to other hospitals, and 69 were discharged. Patients with elevated ferritin levels (> 200 ng/mL) had a higher incidence of severity illness when compared with those with normal ferritin levels (≤ 200 ng/mL) (50.0% vs 2.9%). In addition, severity illness manifested significantly higher level of ferritin as compared with non-severe ones (median 921.3 vs 130.7 ng/mL, p < 0.001). Furthermore, ferritin could effectively discriminate severity and non-severity, with an area under the ROC curve (AUC) reaching 0.873 (sensitivity 96%, specificity 70%), larger than that of age (0.697), C-reactive protein (0.730) and lymphocytes% (0.717). Combined model incorporating multivariate revealed a similar manner with ferritin alone (p = 0.981). Furthermore, elevated ferritin group showed longer viral clearance time (median 16 vs 6 days, p < 0.001) and in-hospital length (median 18 vs 10 days, p < 0.001). Our results suggest that ferritin could act as a simple and efficacious complementary tool to identify severe COVID-19 patients at early stage and predict their outcome. This indicator would provide guidance for subsequent clinical practice, alleviate the medical stress and reduce the mortality.
Crohn's disease and growth deficiency in children and adolescents (2014)

Nutritional concerns, linear growth deficiency, and delayed puberty are currently detected in up to 85% of patients with Crohn's disease (CD) diagnosed at childhood. To provide advice on how to assess and manage nutritional concerns in these patients, a Medline search was conducted using "pediatric inflammatory bowel disease", "pediatric Crohn's disease", "linear growth", "pubertal growth", "bone health", and "vitamin D" as key words. Clinical trials, systematic reviews, and meta-analyses published between 2008 and 2013 were selected to produce this narrative review. Studies referring to earlier periods were also considered if the data was relevant to our review. Although current treatment strategies for CD that include anti-tumor necrosis factor-α therapy have been shown to improve patients' growth rate, linear growth deficiencies are still common. In pediatric CD patients, prolonged diagnostic delay, high initial activity index, and stricturing/penetrating type of behavior may cause growth deficiencies (in weight and height) and delayed puberty, with several studies reporting that these patients may not reach an optimal bone mass. Glucocorticoids and inflammation inhibit bone formation, though their impact on skeletal modeling remains unclear. Long-term control of active inflammation and an adequate intake of nutrients are both fundamental in promoting normal puberty. Recent evidence suggests that recombinant growth factor therapy is effective in improving short-term linear growth in selected patients, but is of limited benefit for ameliorating mucosal disease and reducing clinical disease activity. The authors conclude that an intense initial treatment (taking a "top-down" approach, with the early introduction of immunomodulatory treatment) may be justified to induce and maintain remission so that the growth of children with CD can catch up, ideally before puberty. Exclusive enteral nutrition has a key role in inducing remission and improving patients' nutritional status.
Interferon-?1b treatment modulates cytokines in patients with primary progressive multiple sclerosis (2006)

Interleukin-10 serum levels rose in IFN-beta1b-treated patients as has been observed in RRMS. The changes in cytokine patterns secreted by T-lymphocytes of PPMS patients, however, differ from effects observed in RRMS supporting the hypothesis that PPMS differs in some immunological aspects from RRMS.
Reaction of 4‐hydrazinoquinolines with β‐diketones. Synthesis and spectroscopy (<sup>1</sup>h, <sup>13</sup>c nmr, ms) of some pyrazolylquinolines (1989)

Abstract A series of 4‐pyrazolylquinolines have been prepared from 4‐hydrazinoquinolines and β‐dicarbonyl compounds and the previously proposed diazepine structure for the reaction products has been ruled out. A 13 C nmr study established the 3‐position of the methyl group when two isomers were possible. Finally, a careful 1 H nmr study of 2‐ and 4‐pyrazolylquinolines led to the conclusion that intramolecular hydrogen bonds between aromatic (or heteroaromatic) C‐H and pyridine like nitrogens is the factor that determines the conformation of these compounds.
Gallium maltolate is a promising chemotherapeutic agent for the treatment of hepatocellular carcinoma. (2006)

These data support clinical testing of gallium maltolate, an orally active compound, in the treatment of HCC.
Development of a buccal mucoadhesive film for fast dissolution: mathematical rationale, production and physicochemical characterization (2013)

The validity of a mathematical rationale for preparation of a fast-dissolving buccal mucoadhesive was tested. A buccal mucoadhesive biopolymeric formulation has been developed having pullulan as the main component. The formulation was duly evaluated physicochemically, via assays for intrinsic viscosity (resulting in 71.61 cm3 g(-1)), differential scanning calorimetry analysis (resulting in a Tg = 63 °C), thermogravimetric analysis (244-341 °C), moisture content determinations (14%, w/w), dissolution timeframe (41.6 s), mucoadhesion force (40 kg/cm2), scanning electron microscopy analyses (critical ray under 1.0 μm), mechanic strength (tensile strength = 58 N/mm2, deformation = 4.4%). The mucoadhesive formulation exhibited important characteristics for a drug carrier, that is, a 6 cm2 area, a fast dissolution timeframe, an adequate mucoadhesivity, resistance to both oxygen and water vapor penetration, increased viscosity in solution (ranging from 33.2 cm3/g to 71.61 cm3/g), easy molding, suitable water solubility and transparency.
Elucidating Multiscale Periosteal Mechanobiology: A Key to Unlocking the Smart Properties and Regenerative Capacity of the Periosteum? (2012)

The periosteum, a thin, fibrous tissue layer covering most bones, resides in a dynamic, mechanically loaded environment. The periosteum also provides a niche for mesenchymal stem cells. The mechanics of periosteum vary greatly between species and anatomical locations, indicating the specialized role of periosteum as bone's bounding membrane. Furthermore, periosteum exhibits stress-state-dependent mechanical and material properties, hallmarks of a smart material. This review discusses what is known about the multiscale mechanical and material properties of the periosteum as well as their potential effect on the mechanosensitive progenitor cells within the tissue. Furthermore, this review addresses open questions and barriers to understanding periosteum's multiscale structure-function relationships. Knowledge of the smart material properties of the periosteum will maximize the translation of periosteum and substitute periosteum to regenerative medicine, facilitate the development of biomimetic tissue-engineered periosteum for use in instances where the native periosteum is lacking or damaged, and provide inspiration for a new class of smart, advanced materials.
MATHEMATICAL MODELING and EXPERIMENTAL STUDIES ON OHMIC HEATING of LIQUID‐PARTICLE MIXTURES IN A STATIC HEATER<sup>1</sup> (1992)

ABSTRACT Understanding of the ohmic heating of liquid‐particle mixtures requires preliminary study and model development within a static heater. A mathematical (3D finite element) model was developed for prediction of temperatures of mixtures of liquids and multiple particles within a static heater. Experiments were conducted using cubic potato particles within sodium phosphate solutions, for various particle sizes, orientations, concentrations, and liquid conductivities. the mathematical model was found to yield satisfactory prediction of experimental trends. Critical parameters affecting the relative heating rates of particles and liquid were the conductivities of the two phases, and the volume fraction of each phase. Ohmic heating appears most promising with high‐solids concentration mixtures.
Understanding the value proposition as a co-created claim (2015)

In this paper, we examine five cases of technology commercialization in terms of how entrepreneurs advance a specific kind of claim: the value proposition. The value proposition can describe the characteristics of the innovation itself (Goods-Dominant Logic) or propose how the innovation will co-create value with stakeholders (Service-Dominant Logic); in the examined cases, the value proposition transitions between these two “logics,” addressing different needs in the ongoing argument. We conclude by discussing the needs that each “logic” serves and the implications for better understanding entrepreneurship communication.
Ring oscillators for functional and delay test of latches and flip-flops (2011)

This work proposes a novel design strategy to use ring oscillators for functional validation and delay test of storage elements (latches and flip-flops). Besides the logic verification, power consumption and aging effect analysis can also be efficiently performed for the circuits under test. The proposed test solutions are also quite suitable for self-timed and self-checking full verification of latches and flip-flops, as well as for comparing different implementations of such sequential cells. This test approach has been validated at the gate level by using HDL descriptions as well as at the transistor level through electrical simulations.
A comparison of count rate parameters in gamma cameras. (1981)

Pulse pile-up is a fundamental problem that limits the ability of a gamma camera to produce high quality images at high count rates. Pulse pile-up results in loss of events and spatial distortions in the image. The question asked in this study is how well do some of the test procedures for measuring count rate performance in gamma cameras compare. In four gamma cameras we compared measurements of spectral fraction, count-rate curve, pulse-pair resolution, deadtime, maximum count rate, full width at half maximum of the line spread function, and misplaced event count rate. The results indicated that no one technique provides a complete description of the count-rate effects in gamma cameras. The misplaced-event measurements provided the most information.
Altered estrogen receptor alpha and beta messenger RNA expression during human breast tumorigenesis. (1998)

Using a multiplex reverse transcription-PCR assay, we compared the relative expression of estrogen receptor (ER) alpha and ER-beta mRNA between adjacent samples of normal breast tissue and matched primary breast tumors obtained from 18 different patients. Within this cohort, 7 tumors were ER negative, and 11 tumors were ER positive, as determined by the ligand binding assay. No differences in the ratio of ER-alpha:ER-beta expression were observed in the ER-negative cohort. However, in the ER-positive cohort, a significantly (P < 0.02) higher ER-alpha:ER-beta ratio was observed in the tumor compared with that of the normal tissue component. Our data revealed that the increase in the ER-alpha:ER-beta ratio was due primarily to a significant (P < 0.05) increase in ER-alpha mRNA expression in conjunction with a lower ER-beta mRNA expression in the tumor compared with that of the normal compartment in some, but not all, ER-positive cases. These results suggest that the role of ER-alpha- and ER-beta-driven pathways and/or their interaction change during breast tumorigenesis.
A Dynamic Service Migration Mechanism in Edge Cognitive Computing (2019)

Driven by the vision of edge computing and the success of rich cognitive services based on artificial intelligence, a new computing paradigm, edge cognitive computing (ECC), is a promising approach that applies cognitive computing at the edge of the network. ECC has the potential to provide the cognition of users and network environmental information, and further to provide elastic cognitive computing services to achieve a higher energy efficiency and a higher Quality of Experience (QoE) compared to edge computing. This article first introduces our architecture of the ECC and then describes its design issues in detail. Moreover, we propose an ECC-based dynamic service migration mechanism to provide insight into how cognitive computing is combined with edge computing. In order to evaluate the proposed mechanism, a practical platform for dynamic service migration is built up, where the services are migrated based on the behavioral cognition of a mobile user. The experimental results show that the proposed ECC architecture has ultra-low latency and a high user experience, while providing better service to the user, saving computing resources, and achieving a high energy efficiency.
The Simulation Analysis of Electromagnetic Repulsion Mechanism for High-voltage Current-Limiting Fuse (2017)

The research content of this topic is based on Electromagnetic Repulsion Mechanism for High-voltage Current-limiting Fuse, according to the given parameters, and basing on the reasonable simplified, the topic establishes 2D finite element simulation model by using Ansoft Maxwell, and simulates the dynamic characteristics. The influence law of electromagnetic repulsion mechanism will be found out by simulating these influencing factors, such as repulsion mechanism, electromagnetic repulsion, and movement speed. Finally the topic concludes a general design guiding principle which strives to increase the speed of electric repulsion between contacts rapidly and improve the current-limiting ability of current-limiting fuse by producing short circuit current.
Magnetic-field-sensitive polymer composite materials (1994)

Polymer composite material, containing conducting filler particles (e.g. graphite) at concentrations above the percolation threshold should, as a conductor, exhibit certain magnetic-field-sensitive properties, such as the Hall effect or magnetoresistance. These effects not only allow them to be classified as smart materials, but also help in establishing the mechanism of conduction in such complex disordered systems. This paper reports the results of investigations on magnetoresistance in composite materials, prepared by direct polymerization of propylene on graphite particles. The method ensures grafting of polymer to the filler surface, imparting the properties to the composite. For composites with graphite, the magnetoresistance is positive for a filler volume fraction above the percolation threshold. Below the threshold the samples show weak negative magnetoresistance, characteristic of conduction through localized states in disordered systems. This result correlates with our model of double percolation over filler particles, surrounded by thin layers of injected charge. New magnetic effects have been found, such as oscillations of dark conductivity in magnetic field and resonance magnetic-spin effects.
Automatic realtime offset calibration of gyroscopes (2013)

This paper reports on realtime offset calibration of a three-axis gyroscope, especially, offset calibration of a gyroscope exclusively based on the redundant information of one three-axis accelerometer. The self calibration is based on the knowledge that the output of any gyroscope equals zero if the inertial measurement unit is in a static position. For this purpose, a sophisticated movement recognition has been developed using unaligned acceleration signals containing sensitivity and offset errors. The proposed movement recognition identifies not exclusively human caused activities, which is state of the art, but rather extends the sensibility to small, constant yaw rates which are close to the ground noise floor of the static gyroscope. These very small, constant yaw rates are in the range of possible offsets and not identified through previously presented movement recognitions. The effectiveness of the proposed movement recognition overcomes this drawback and enables the complete rejection of the environmental dependent offset of any gyroscope. The performance of the auto calibration algorithm has been evaluated by means of simulations, human movement patterns and movement patterns generated through a turn table.
Immunologic Responses Associated with 12 Weeks of Combination Antiretroviral Therapy Consisting of Zidovudine, Lamivudine, and Ritonavir: Results of AIDS Clinical Trials Group Protocol 315 (1998)

Human immunodeficiency virus (HIV)-1 infection is associated with progressive cell-mediated immune deficiency and abnormal immune activation. Although highly active antiretroviral therapy regimens can increase circulating CD4 T lymphocyte counts and decrease the risk of opportunistic complications, the effects of these treatments on immune reconstitution are not well understood. In 44 persons with moderately advanced HIV-1 infection, after 12 weeks of treatment with zidovudine, lamivudine, and ritonavir, plasma HIV-1 RNA fell a median of 2.3 logs (P < .0001). Circulating numbers of naive and memory CD4 T lymphocytes (P < .001), naive CD8 T lymphocytes (P < .004), and B lymphocytes (P < .001) increased. Improved lymphocyte proliferation to certain antigens and a tendency to improvement in delayed-type hypersensitivity also were seen. Dysregulated immune activation was partially corrected by this regimen; however, the perturbed expression of T cell receptor V regions in the CD4 and CD8 T lymphocyte populations was not significantly affected. Ongoing studies will ascertain if longer durations of virus suppression will permit more complete immune restoration.