gebhart/patrepeval huggingface dataset:
Post-exposure prophylaxis vaccination rate and risk factors of human rabies in mainland China: a meta-analysis (2018)

Rabies is one of the major public health problems in China, and the mortality rate of rabies remains the highest among all notifiable infectious diseases. A meta-analysis was conducted to investigate the post-exposure prophylaxis (PEP) vaccination rate and risk factors for human rabies in mainland China. The PubMed, Web of Science, Chinese National Knowledge Infrastructure, Chinese Science and Technology Periodical and Wanfang databases were searched for articles on rabies vaccination status (published between 2007 and 2017). In total, 10 174 human rabies cases from 136 studies were included in this meta-analysis. Approximately 97.2% (95% confidence interval (CI) 95.1-98.7%) of rabies cases occurred in rural areas and 72.6% (95% CI 70.0-75.1%) occurred in farmers. Overall, the vaccination rate in the reported human rabies cases was 15.4% (95% CI 13.7-17.4%). However, among vaccinated individuals, 85.5% (95% CI 79.8%-83.4%) did not complete the vaccination regimen. In a subgroup analysis, the PEP vaccination rate in the eastern region (18.8%, 95% CI 15.9-22.1%) was higher than that in the western region (13.3%, 95% CI 11.1-15.8%) and this rate decreased after 2007. Approximately 68.9% (95% CI 63.6-73.8%) of rabies cases experienced category-III exposures, but their PEP vaccination rate was 27.0% (95% CI 14.4-44.9%) and only 6.1% (95% CI 4.4-8.4%) received rabies immunoglobulin. Together, these results suggested that the PEP vaccination rate among human rabies cases was low in mainland China. Therefore, standardised treatment and vaccination programs of dog bites need to be further strengthened, particularly in rural areas.
IPv6 Multihoming Support at Site Exit Routers (2001)

The document describes a mechanism for basic IPv6 multihoming support, and its operational requirements. Unlike currently- practiced IPv4 multihoming, the technique does not impact the worldwide routing table size, nor IGP (Interior Gateway Protocol) routing table size in upstream ISPs. The mechanism can be combined with more sophisticated (or complex) multihoming support mechanisms, and can be used as a foundation for other mechanisms. The document is largely based on RFC 2260 by Tony Bates.
Preparation of High Permittivity GdScO<sub>3</sub> Films by Liquid Injection MOCVD (2009)

We describe preparation and properties of GdScO3 thin films. The films were prepared by liquid injection metal-organic chemical vapor deposition, MOCVD at 600 ºC on (100) Si substrate. The as-deposited films were amorphous with a smooth surface and sharp GdScO3/Si interface. X-ray diffraction showed that the amorphous phase is well preserved upon rapid thermal annealing up to 1000 ºC. However, modification of the X-ray reflectivity pattern after annealing at 1000 ºC indicates increasing of the film thickness, presumably due to diffusion of silicon from the substrate into the whole volume of the film. Capacitance-voltage measurement resulted in dielectric constant of 22. It is shown, that exact stoichiometry of GdScO3 is not necessary to achieve dielectric constant above 20.
Perspectives on human clinical trials of therapies using iPS cells in Japan: Reaching the forefront of stem-cell therapies (2013)

A research project involving sheets of retinal pigment epithelium constructed from iPS cells derived from patients with age-related maculopathy is one step closer to being approved for clinical trials by the Japanese Government. Now is the time to make therapies using iPS cells clinically available.
Sociale economie in 2015 (2009)

A total of 1345 elementary schoolchildren from grades 1-3 (aged 7-9 years) were examined and treated by community health center dentists during 1975-1977. The combined effect of fissure sealing and topical fluoride therapy with 2% NaF gel resulted over the 2 years in an increase in the proportion of caries-free permanent first molars from 50% to 81% in the 1st grade. The mean DMFS scored from the same teeth decreased from 2.8 to 0.8. In the age group born in 1968 the increment of new carious surfaces was 0.28 DFS/year with sealing and 1.13 DFS/year without.
Robust Formation of Skyrmions and Topological Hall Effect Anomaly in Epitaxial Thin Films of MnSi (2013)

Magnetotransport properties have been investigated for epitaxial thin films of B20-type MnSi grown on Si(111) substrates. Lorentz transmission electron microscopy images clearly point to the robust formation of Skyrmions over a wide temperature-magnetic field region. New features distinct from those reported previously for MnSi are observed for epitaxial films: a shorter (nearly half) period of the spin helix and Skyrmions, and a topological Hall effect anomaly consisting in ∼2.2 times enhancement of the amplitude and in the opposite sign with respect to bulk samples.
A 16-kbit block addressed charge-coupled memory device (1976)

This paper describes the design and performance of a 16- kbit charge-coupled serial memory device. The memory is organized in four blocks of 4 kbits each with on-chip decoding and is mounted in a 16-pin ceramic dual-in-line hermetic package. Each 4-kbit block is organized as a serial-parallel-serial (SPS) array. Operated at a data rate of 1 MHz the mean access time is 2 ms and the on-chip power dissipation is calculated to be 1.5 µW/bit with another 0.5 µW/bit being required in off-chip clock drivers. The maximum designed output data rate is 10 MHz. Compared to the serpentine and loop organized memory charge-coupled device (CCD), the SPS organization has the advantages of lower power dissipation, greater tolerance to process parameter variations, and higher output data rate. All inputs and outputs are TTL compatible. Write/recirculate control is provided on the chip as well as two-dimensional decoding to permit memory matrix organization with X, Y chip select control. All the on-chip peripheral circuits use dynamic MOS circuitry to minimize power consumption. The charge sensing on the chip is achieved with balanced regenerative sense amplifiers. The memory array uses the three-phase three-level polysilicon electrode structure, and the chip is fabricated using an MOS n-channel polysilicon gate process with self-aligned source, drain, and channel stop.
Epidemiologic Studies of Lung Disease Due to Mycobacteria Other than Mycobacterium tuberculosis in Japan (1981)

The incidence of lung disease due to mycobacteria other than Mycobacterium tuberculosis (atypical mycobacteria) in Japan was estimated to be 0.9--1.9 per 10(5) population per year in 1971--1979. Although the incidence of lung tuberculosis is steadily decreasing, the incidence of lung disease due to atypical mycobacteria has remained at almost the same level. The number of patients newly infected per year in recent years was calculated to be approximately 2,000. The ratio of the number of patients with lung disease due to atypical mycobacteria to the number of patients with lung disease due to atypical mycobacteria to the number of patients with lung disease due to all species of mycobacteria was highest in hospitals on the southwest coast of the Pacific. The atypical mycobacteria that caused disease most frequently belonged to the Mycobacterium avium-intracellulare complex. Of the 537 cases of disease due to atypical mycobacteria, 491 (89.6%) were due to these organisms; 43 (8.0%), to Mycobacterium kansasii; and 7 (1.3%), to Mycobacterium fortuitum. The disease due to M. kansasii appeared most frequently in hospitals in the Tokyo and Kanagawa prefectures. Patients with lung tuberculosis had a high risk of lung infection due to M. avium-intracellulare. The incidence of such disease in tuberculous patients was estimated to be 18.7 per 10(5) population per year, a rate that is approximately 10 times that found in the general population.
The Dutch Implementation of the Data Retention Directive: On the Storage and Use of Telephone and Internet Traffic Data for Crime Investigation Purposes (2014)

The Dutch implementation of the Data Retention Directive was adopted on the 1st of September, 2009. The main reason for the storage of call detail records of telephone and internet traffic data is its potential in the aid of the investigation and prosecution of serious crimes.\n\nHowever the fact that this data has to be stored for a certain period of time is a recurring point of debate. There is a need both in the Netherlands and at European level (EU 18620/11) for a clearer understanding of how the police and judicial authorities use the data kept under the Telecommunications Data Retention Act (referred to below as ‘the Act’). The purpose of this study is to clarify how the Act works in practice.\n\nThe same report in Dutch was published in 2013 (See link at: More information)
Glomerular diseases associated with hepatitis C virus infection. (2012)

Renal diseases associated with hepatitis C virus (HCV) infection are a significant problem for clinicians and diagnostic pathologists. A wide variety of disorders, including a spectrum of immune-complex glomerulonephritides, has been reported in association with hepatitis and cirrhosis caused by HCV. For some of these diseases, including membranoproliferative glomerulonephritis type I and cryoglobulinemic glomerulonephritis, plausible links between HCV and the glomerular pathology have been proposed. In other cases, the role of the virus in the pathogenesis of the renal disease is less certain. This communication catalogues the renal manifestations of HCV infection, providing clinical and pathological descriptions of the most prevalent disorders. Where available, evidence implicating HCV in the causation of the disorders is also discussed.
Adenovirus-Antibody Complexes Contributed to Lethal Systemic Inflammation in a Gene Therapy Trial (2020)

Intra-arterial administration of an adenovirus serotype 5 (Ad5) vector in a gene therapy trial caused lethal, systemic inflammation in subject 019 with ornithine transcarbamylase deficiency. This unanticipated inflammatory response was absent in another subject receiving the same vector dose and in 16 subjects receiving lower vector doses. We hypothesized that an immune memory to a previous natural adenovirus infection enhanced the immune response to high-dose systemic Ad5 vector, causing the exaggerated immune response in subject 019. To investigate this, we found that rabbit polyclonal sera to Ad5 and pooled human immunoglobulin (Ig) inhibited Ad5 vector transduction of non-immune cells in vitro, but enhanced transduction and activation of human dendritic cells (DCs). Sera from approximately 7% of normal human subjects and 50% of patients treated topically with Ad5 vectors enhanced Ad5 transduction and activation of DCs, apparently from formation of Ig-Ad5 immune complexes and binding to DCs through FcγR. Subject 019's blood substantially increased Ad5-vector activation of human DC primary cultures at levels exceeding those from normal subjects. Although this study is based on one event in a single subject, the results implicate a pre-existing humoral immune response to Ad5 in the lethal systemic inflammatory response that occurred in subject 019.
The thermal expansion shear separation (TESS) technique for producing thin self-supporting silicon films for low-cost solar cells (1980)

A new technique-Thermal Expansion Shear Separation (TESS)- is described for producing thin self-supporting polycrystalline silicon ribbons using temporary molybdenum substrates. The TESS substrates and separated silicon ribbons were characterized to determine the shear separation mechanism, limits to substrate recyclability, and the quality of the silicon ribbon for efficient solar-cell fabrication. Solar cells fabricated on the silicon ribbons separated from molybdenum substrates have exhibited AM1 conversion efficiencies of up to 11.8 percent after ribbon-to-ribbon (RTR) grain enhancement. By recycling the Mo substrate its cost contribution can be as low as $0.0074/peak watt of electricity produced.
Dysregulation of IL-15-mediated T-cell homeostasis in TGF-β dominant-negative receptor transgenic mice (2006)

T-cell subpopulations, defined by their expression of CD4, CD8, naive, and memory cell-surface markers, occupy distinct homeostatic compartments that are regulated primarily by cytokines. CD8+ memory T cells, as defined by CD44(hi) surface expression, are dependent on IL-15 as a positive regulator of their homeostatic maintenance. Manipulation of IL-15 signaling through gene aberration, overexpression, or receptor alterations has been shown to dramatically affect T-cell homeostasis, with overexpression leading to fatal leukemia. Here we show that TGF-beta is the critical negative regulator of murine CD8+ memory T-cell homeostasis with direct opposition to the positive effects of IL-15. This negative regulation is mediated, at least in part, by the ability of TGF-beta to modulate expression of the beta-chain of the IL-15 receptor, thus establishing a central axis between these 2 cytokines for homeostatic control of CD8+ memory T-cell populations. These data establish TGF-beta as a critical and dominant tumor-suppressor pathway opposing IL-15-mediated CD8+ T-cell expansion and potential malignant transformation.
Adsorption of C<sub>1</sub>−C<sub>7</sub> Normal Alkanes on BAX-Activated Carbon. 2. Statistically Optimized Approach for Deriving Thermodynamic Properties from the Adsorption Isotherm (2000)

A new stepwise (SW) statistically optimized model and also a virial-type (VT) model were correlated successfully with adsorption equilibria for the n-alkane series C1−C7 on Westvaco BAX-1100 activated carbon over a wide range of temperatures and pressures. Both models predicted reasonable temperature-dependent isosteric heats of adsorption, and from these slight dependencies, sensible deviations between the adsorbed- and gas-phase heat capacities were indicated. However, the SW model was more reliable under extreme conditions. The SW model also showed that the observed linear dependence of ln(P) on 1/T at constant loading, according to the Clausius−Clapeyron equation, only occasionally contributed to the overall description; statistically, more complicated temperature dependencies of ln(P) were revealed, indicating that the temperature dependence of the isosteric heat of adsorption can be easily overlooked. The ideal-gas assumption, inherent in the Clausius−Clapeyron equation, was also relaxed. The resulting real-gas isosteric heats of adsorption were reduced compared to the ideal-gas values, especially at high loadings and high temperatures. Finally, the temperature-independent isosteric heats of adsorption predicted from the potential theory correlation developed in Part 1 of this series fell almost in the exact middle of the range predicted by the temperature-dependent SW and VT models for the lightly to moderately adsorbed alkanes, but severely underpredicted those for the heavily adsorbed alkanes (i.e., heavier than n-propane).
Managing Purple Nutsedge (<i>Cyperus rotundus</i>) Populations Utilizing Herbicide Strategies and Crop Rotation Sequences (1999)

Field experiments were conducted in North Carolina from 1994 through 1998 to evaluate the effects of five weed management strategies and four corn ( Zea mays)–peanut ( Arachis hypogaea ) rotation sequences on purple nutsedge ( Cyperus rotundus ) population development. Effects of these weed management programs on cotton ( Gossypium hirsutum ) and peanut production in following years were also investigated. Herbicide programs included a nontreated control, a carbamothioate preplant incorporated (PPI) combination treatment utilizing vernolate in peanut and butylate in corn, an early postemergence (EPOST) acetolactate synthase (ALS) inhibitor combination treatment utilizing imazapic in peanut and halosulfuron in corn, and EPOST treatments of imazapic and imazethapyr in both peanut and imidazolinone-resistant corn. Crop rotation sequences for the 3 yr included continuous corn (CCC), corn–peanut–corn (CPC), peanut–corn–peanut (PCP), and continuous peanut (PPP). The imazapic and ALS inhibitor combination treatments both provided excellent shoot and tuber control. After 3 yr, imazapic and the ALS inhibitor combination treatment reduced shoot and tuber population densities to less than 10% of the nontreated control. Imazethapyr provided variable but better control than the carbamothioate treatment with tuber densities (measured from 0 to 15 cm soil depth) and shoot densities increasing from 733 to 2,901 tubers/m 3 of soil and 16 to 43 shoots/m 2 , respectively, after 3 yr. Tuber densities increased in the nontreated control from 626 to 9,145 tubers/m 3 of soil and from 962 to 5,466 tubers/m 3 of soil in the carbamothioate treatment during this same period. Also, shoot densities increased in the nontreated control from 22 to 159 shoots/m 2 and from 8 to 92 shoots/m 2 in the carbamothioate treatment. There was a 31% peanut yield reduction from 1994 to 1996 when peanut was continuously planted or rotated to corn for only 1 yr. Herbicide carryover effects were not observed in cotton during 1997.
All Wired Up and Ready to Go (2002)

The School of Law's new facility is one of the most technologically advanced legal education buildings in the country. Read what the buzz is all about.
Concurrency annotations (1992)

article Free Access Share on Concurrency annotations Author: Klaus-Peter Löhr View Profile Authors Info & Claims ACM SIGPLAN NoticesVolume 27Issue 10Oct. 1992 pp 327–340https://doi.org/10.1145/141937.141964Published:31 October 1992Publication History 10citation345DownloadsMetricsTotal Citations10Total Downloads345Last 12 Months4Last 6 weeks1 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my Alerts New Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
In Vivo Reduction of Bacterial Populations in the Urinary Tract of Catheterized Sheep by Iontophoresis (1995)

Since iontophoresis safely reduced bacterial populations in catheterized sheep, this technology may reduce or eliminate nosocomial, catheter-induced urinary tract infections in humans.
Improving harmonics of a current controlled parallel resonant dual converter (1994)

This paper is concerned with space vector control strategies to determine adequate switching states that lead to a reduction of the error vector of both the input power converter and output inverter of a parallel resonant DC link dual power converter. The control of the input power converter is based on the input current error vector. Three different switching strategies are studied. The error vector of the output inverter is defined in two ways. The first method is based on the total stationary flux error vector and the other on the filtered output voltage error proposed in this paper. The goal of the proposed method is to reduce the low-order harmonic content of the output current. The basis of the comparison of the three switching strategies is the harmonic content obtained by computer simulation. >
Improving efficiency through analysis of data obtained from an RFID tag system for surgical instruments (2015)

The number of surgical instruments that must be managed can be up to 100 for a single operation. Careful counting before and after an operation and proper identification of each instrument being stored in a container after sterilization are indispensable to patient safety. In the past this has required a great amount of hand labor. To improve efficiency, Shimane University Hospital introduced a system called SIMSAFE that uses RFID tags. The data obtained promotes effective and efficient instrument management. This paper introduces the management of surgical instruments when using SIMSAFE and shows the results of a preliminary data analysis.
Making mobile code both safe and efficient (2004)

Mobile programs can potentially be malicious. To protect itself, a host that receives such mobile programs from an untrusted party or via an untrusted network connection will want some kind of guarantee that the mobile code is not about to cause any damage. The traditional solution to this problem has been verification, by which the receiving host examines the mobile program to discover all its actions even before starting execution. Unfortunately, aside from consuming computing resources in itself, verification inhibits traditional compiler optimizations, making such verifiable mobile code much less efficient than native code. We have found an alternative solution by identifying a class of mobile-code representations in which malicious programs can simply not be encoded to begin with. In such an encoding, verification turns into an integral part of the decoding routine. Moreover, support for high-quality justin-time code generation can be provided. We present two such encodings, one based on highly effective compression of abstract syntax trees, and another based on a referencesafe and type-safe variant of Static Single Assignment form. Parts of this material were previously published under the title “Project transPROse: Reconciling Mobile-Code Security With Execution Efficiency” in The Second DARPA Information Survivability Conference and Exhibition (DISCEX II), Anaheim, California, June 2001, IEEE Computer Society Press, ISBN 0-7695-1212-7, pp. II.196–II.210. This research effort was sponsored by the Defense Advanced Research Projects Agency (DARPA) and Air Force Research Laboratory (AFRL), Air Force Materiel Command, USAF, under agreement number F30602-99-1-0536. The U.S. Government is authorized to reproduce and distribute reprints for Governmental purposes notwithstanding any copyright annotation thereon. The views and conclusions contained herein are those of the authors and should not be interpreted as necessarily representing the official policies or endorsements, either expressed or implied, of DARPA, AFRL, or the U.S. Government.
Development of Anhydrous Ethanol Purification: Reduction of Acetal Content and Vapor–Liquid Equilibrium Study of the Ethanol–Acetal Binary System (2021)

Acetaldehyde diethyl acetal (herein called acetal) is an important pollutant of anhydrous ethanol. Isobaric vapor-liquid equilibrium (VLE) of an ethanol-acetal binary system was measured using a vapor condensate and liquid circulation VLE still. The experimental data were correlated with Wilson, nonrandom two-liquid (NRTL), and universal quasichemical (UNIQUAC) activity coefficient models, which were found suitable for representing the VLE data. Proper agreements between experimental and calculated VLE data were obtained, which were then confirmed with consistency tests. The applicability of the novel VLE data was demonstrated during an investigation of an anhydrous ethanol purification column. Reduction of the concentration of acetal and other pollutants was examined and optimized in a flowsheet environment. The modeling results were verified in a laboratory with an experimental distillation column, confirming a correct agreement between the results. It must be highlighted that the developed method is suitable for the production of pharmacopeial quality anhydrous alcohol, based on reliable, verified VLE data. The results show the importance of accurate VLE data in critical compositions (low pollutant content); moreover, aiming at high product purity, experimental validation has paramount importance. The consistency between the three platforms (VLE and distillation experiments and flowsheet simulation) confirms the accuracy of the developed method.
Genome-Wide Linkage and Follow-Up Association Study of Postpartum Mood Symptoms (2009)

This is the first study to examine the genetic etiology of postpartum mood symptoms using genome-wide data. The results suggest that genetic variations on chromosomes 1q21.3-q32.1 and 9p24.3-p22.3 may increase susceptibility to postpartum mood symptoms.