gebhart/patrepeval huggingface dataset:
Advances in folliculosebaceous cystic hamartoma (2011)

Clinically, folliculosebaceous cystic hamartoma (FSCH)is uncommon and lacks distinct features. It often manifests as asymptomatic, skin-colored papules or nodules mostly distributed on the face. Histopathologically, it is a kind of hamartoma of skin appendages mainly characterized by the hyperplasia of folliculosebaceous units and mesenchymal tissues. The differential diagnosis mainly includes sebaceous trichofolliculoma and dermoid cyst. Its immunohistochemical manifestations are unspecific and associated with epithelial and non-epithelial component within the hamartoma. This paper presents an update on the knowledge about clinical and immunohistochemical manifestation of, diagnostic criteria and treatment for FSCH.

Key words: 
Hamartoma;  Epidermal cyst;  Hair follicle;  Sebaceous glands
On the Optimal Pole Width for Direct Drive Linear Wave Power Generators Using Ferrite Magnets (2018)

In this work, ferrite magnet linear generators for wave power applications are considered. These machines operate at unusually low speeds, around and even below 1 m/s, at which the optimal geometry differs from standard machines, since the copper loss and the force density become considerably more important. The focus is on translator design, and analytical two-dimensional (2D) expressions for the optimal 2D geometry are derived. Finite Element Analysis (FEA) is also applied to verify the analytical expressions and to determine effects from leakage fluxes and iron saturation. Demagnetization of ferrite magnets is also discussed and calculations are made to show the demagnetization situation for the magnets in different geometries. Finally, an example generator design is made to illustrate the findings. This generator is compared to three other generator concepts. It is concluded that ferrite magnet generators can have at least nearly the same shear stress as surface mounted neodymium magnet generators at low speed if the airgap is 3 mm or less, provided that a proper pole length is chosen, and that they can be economically competitive to neodymium magnet generators for wave power. It is also concluded that the demagnetization situation for the magnets can be severe, and that the choice of magnet grade and pole length is crucial in this respect.
Activation of Stat3 in renal tumors. (2009)

Signal transducer and activator of transcription 3 (Stat3) plays a vital role in signal transduction pathways that mediate transformation and inhibit apoptosis. Oncogenic Stat3 is persistently activated in several human cancers and transformed cell lines. Previous studies indicate activation of Stat3 in renal cell carcinoma (RCC). However, the detailed characterization of the Stat3 expression pattern in different histologic types of RCC is lacking. We have analyzed the immunoprofile of activated or phosphorylated Stat3 (pStat3) in a tissue microarray of renal tumors of different histologic types, including 42 cases of conventional clear cell type, 24 chromophobe, and 7 papillary, 15 oncocytoma, 7 urothelial carcinoma and 21 normal kidney tissues using an anti-pStat3 antibody (recognizes only activated STAT3). pStat3 nuclear staining was observed in 25 of 42 conventional clear cell RCC (59.5 %), 8 of 24 chromophobe RCC (33.3%), 4 of 7 papillary RCC (57.1%). In the other tumor groups, 4 of 15 oncocytomas (26.7%) and 6 of 7 urothelial carcinomas (85.7%) showed positive nuclear staining. Weak nuclear immunoreactivity for pStat3 was seen in 4 of 21 cases of non-neoplastic kidney tissue (19.0%). The extent of Stat3 activation as determined by nuclear expression of its phosphorylated form is increased in histologic types of renal tumors with greater malignant potential, specifically conventional clear cell RCC, papillary RCC and urothelial carcinoma, only slightly increased in chromophobe RCC, and not increased in oncocytoma. These results suggest a role of Stat3 activation in different types of renal neoplasia, possibly serving as a prognostic marker or therapeutic target.
Fixed-bed photocatalysts for solar decontamination of water (1994)

A solar decontamination process for water was developed using TiO2 photocatalysts supported on silica-based material. The supported catalysts were systematically optimized with respect to catalyst type, catalyst dosage, silica-based support material, particle size, catalyst/support bonding, and calcination temperature. The optimized supported catalysts outperformed an optimized slurry catalyst under identical operational conditions and had a reaction rate four times that of the slurry catalyst. Trichloroethylene (TCE) as a model compound was also used to investigate the impact of solar irradiance, influent concentration, pH value, and hydraulic loading. Supported photocatalysts displayed high light efficiencies over a wide range of weather conditions, an apparent quantum yield of 40% was obtained in a rainy late-afternoon experiment. The complete mineralization of TCE was achieved, and in addition, background natural organic matter (BNOM) in a local surface water did not interfere with the degradation significantly. © 1994, American Chemical Society. All rights reserved.
Interleukin‐6 Receptor Blockade Enhances CD39+ Regulatory T Cell Development in Rheumatoid Arthritis and in Experimental Arthritis (2013)

In both CIA and RA, the frequency of functionally suppressive CD39+ Treg cells is increased as a result of anti-IL-6R treatment, whereas Th17 cells are unaffected. The modification of Treg cell frequency and phenotype may be one of the mechanisms involved in the therapeutic effect of IL-6 blockade in RA.
Unified Mitchell-based Approximation for Efficient Logarithmic Conversion Circuit (2014)

This paper presents a novel method named the Unified Mitchell-based Approximation (UMA) to obtain an optimized Mitchell-based logarithmic conversion circuit for any desired conversion accuracy up to 14 bits. UMA is the first method that is able to obtain a conversion circuit when a specific accuracy is required. In this work, we studied and analyzed five design parameters and their impact on accuracy and hardware merits. We formulate the hardware model of the error correction circuit in the conversion circuit for performance evaluation. Given an accuracy requirement, the proposed method explores the design space of the five design parameters. As the design space is theoretically huge, we propose constraints for the range of the parameter values and develop a systematical search algorithm for exploring the design space. UMA is able to obtain an area-delay product optimized circuit for each of the conversion accuracies achieved by the existing Mitchell-based designs. Synthesis results in 90 nm CMOS technology show that the circuits obtained are comparable or better than the existing Mitchell-based designs with the same accuracy objective. Nine of the fifteen circuits obtained achieve better area-delay product by more than 50 percent. In addition, UMA is able to obtain circuits for any accuracy from 4 to 14 bits, while the best accuracy achieved by the existing Mitchell-based methods is less than 12 bits.
プログラミングMicrosoft DirectX 9グラフィックスパイプライン (2004)

第１部 ＨＬＳＬシェーダプログラミング（ＨＬＳＬの概要；言語；ＨＬＳＬの例） 第２部 エフェクトプログラミング（エフェクトの概要；アセンブリ言語のエフェクトの例；ＨＬＳＬエフェクトの例） 付録Ａ 頂点の処理 付録Ｂ ＨＬＳＬリファレンス 付録Ｃ エフェクトリファレンス
Shemp: secure hardware enhanced myproxy (2005)

While PKI applications differ in how they use keys, all applications share one assumption: users have keypairs. In previous work, we established that desktop keystores are not safe places to store private keys, because the TCB is too large. These keystores are also immobile, difficult to use, and make it impossible for relying parties to make reasonable trust judgments. Since we would like to use desktops as PKI clients and cannot realistically expect to redesign the entire desktop, this paper presents a system that works within the confines of modern desktops to shrink the TCB needed for PKI applications. Our system (called Secure Hardware Enhanced MyProxy (SHEMP)) shrinks the TCB in space and allows the TCB&apos;s size to vary over time and over various application sensitivity levels, thus making desktops usable for PKI.
Mobility measurements by phase analysis (2001)

A new instrument, based on the principle of phase analysis light scattering (PALS) for the measurement of electrophoretic mobilities, has been produced. Such measurements are particularly useful in the study of dispersions in nonpolar and highly conducting media. The current PALS configuration can be used to measure mobilities up to 3 orders of magnitude lower than with the conventional Doppler mode. The device has a number of new features; in particular, all the signal processing is digital and the optical system features a reference beam configuration. Data are presented to show that on suitable samples both the PALS technique and conventional laser Doppler electrophoresis can be performed on the same instrument and the techniques are in good agreement.
Catalysis of the reduction of molecular oxygen to water at Prussian blue modified electrodes (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCatalysis of the reduction of molecular oxygen to water at Prussian blue modified electrodesKingo Itaya, Nobuyoshi Shoji, and Isamu UchidaCite this: J. Am. Chem. Soc. 1984, 106, 12, 3423–3429Publication Date (Print):June 1, 1984Publication History Published online1 May 2002Published inissue 1 June 1984https://pubs.acs.org/doi/10.1021/ja00324a007https://doi.org/10.1021/ja00324a007research-articleACS PublicationsRequest reuse permissionsArticle Views2300Altmetric-Citations353LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Peak Airway Pressure Increase Is a Late Warning Sign of Partial Endotracheal Tube Obstruction Whereas Change in Expiratory Flow Is an Early Warning Sign (2005)

If peak inspiratory airway pressure (Ppeak) is used to monitor airway patency, progressive obstruction of the endotracheal tube (ETT) resulting from secretions can go undetected for a prolonged period. The reason is that any increase in Ppeak depends not only on the degree of narrowing but also on the inspiratory flow () rate. Although the impact of narrowing on low inspiratory is small, its decelerating effect on the high expiratory is pronounced and, hence, easily detectable. Dividing the volume-flow curve of a passive expiration into five consecutive segments (slices) and calculating the time constants (tau(Epsilon)) of these slices allows for analyzing whether and how expiratory is impeded by a partial obstruction. In nine piglets, during volume-controlled ventilation, three grades of ETT obstruction were created with an external clamp. In all animals the tau(E) increased with ETT obstruction (mean for the first slice: 550 ms with unobstructed ETT; grade 1: 661; grade 2: 877; and grade 3: 1563 ms, respectively) and this increase was significant with grade 2 and 3 obstruction. Ppeak, by contrast, did not increase significantly (base: 13, grade 1: 14, grade 2: 15 cm H(2)O) until the most severe (grade 3: 20 cm H(2)O) obstruction was created. We conclude that partial obstruction of the ETT can be reliably monitored with the expiratory V signal and has the potential of monitoring ETT narrowing in ventilator-dependent patients independent of the inspiratory pattern applied.
Immune Response Following Photodynamic Therapy For Bladder Cancer (1989)

This study was undertaken to determine if photodynamic therapy (PDT) produces an immunologic response in patients treated for bladder cancer. Gamma interferon, interleukin 1-beta, interleukin 2 and tumor necrosis factor-alpha were assayed in the urine of four patients treated with photodynamic therapy for bladder cancer, in seven patients undergoing transurethral procedures, and in five healthy control subjects. Quantifiable concentrations of all cytokines, except gamma interferon, were measured in urine samples from the PDT patients treated with the highest light energies, while no urinary cytokines were found in the PDT patient who received the lowest light energy or in the control subjects. These findings suggest that a local immunologic response may occur following PDT for bladder cancer. Such an immunologic response activated by PDT may be an additional mechanism involved in bladder tumor destruction.
The effect of oral clindamycin and rifampicin combination therapy in patients with hidradenitis suppurativa in Singapore (2018)

Hidradenitis suppurativa (HS) is a chronic inflammatory disease of follicular occlusion characterized by abscesses, draining sinuses, and scarring. The efficacy and tolerability of combination treatment with oral clindamycin and rifampicin have previously been assessed in 4 studies including groups of Caucasian patients. Overall results are promising with reported improvement rates between 71.4% and 85.7%. In this study, we propose that combination therapy is safe and efficacious in the treatment of HS, not only among Caucasians, but also in a group of Asian patients in Singapore.
Antioxidative and oxidative status in muscles of pigs fed rapeseed oil, vitamin E, and copper. (1999)

The susceptibility of a given muscle tissue to lipid oxidation may not only depend on the presence of unsaturated fatty acids and the balance between antioxidants and prooxidants, but also on the composition of the skeletal muscle. In the present study, the effects of dietary supplementation of vitamin E (dl-alpha-tocopheryl acetate) and copper in combination with a high level of monounsaturated fatty acids were examined with regard to the antioxidant concentration and the susceptibility to lipid oxidation of two muscles, longissimus (LD) and psoas major (PM), representing different oxidative capacity. In addition, fatty acid profiles of the backfat and the intramuscular lipids, as well as fresh meat quality traits, were studied. Pigs were allotted to a 3x3 factorial experiment with three levels of dl-alpha-tocopheryl acetate (0, 100, and 200 mg/kg of feed) and three levels of copper (0, 35, and 175 mg/kg of feed) added to a diet containing 6% rapeseed oil. A basal diet (without rapeseed oil) was added to the experimental design, giving a total of 10 dietary treatments. Muscle alpha-tocopherol concentrations increased (P<.001) with increasing dl-alpha-tocopheryl acetate in the feed. The antioxidative status was higher in PM than in LD, when considering the concentration of alpha-tocopherol (P<.001) and the activity of antioxidant enzymes (superoxide dismutase, P<.001; glutathione peroxidase, P = .06). Supplemental copper did not give rise to any deposition of copper in muscle tissue or backfat, but the antioxidant status of PM increased. The susceptibility to lipid oxidation was reduced in LD with increasing dietary dl-alpha-tocopheryl acetate and in PM with increasing dietary copper. Supplemental dl-alpha-tocopherol acetate improved the water-holding capacity of LD (P = .005) and PM (P = .003). The fatty acid composition of the backfat and the triglyceride fraction of the intramuscular fat became more unsaturated with the addition of rapeseed oil to the feed. Higher intakes of monounsaturated fatty acids due to the rapeseed oil were also reflected in the phospholipid fraction of the intramuscular fat, but no influence on the proportion of saturated fatty acids was seen. The susceptibility to lipid oxidation of PM was lower for pigs on the rapeseed oil-based diet than for those on the basal diet. The energy metabolic status of the muscles and the accumulation of calcium by the sarcoplasmic reticulum were not influenced by the dietary treatments, but there were differences between muscle types. The addition of rapeseed oil to the diet reduced the muscular content of glycogen (LD, P = .02; PM, P = .06) and elevated the plasma concentration of free fatty acids (P = .05). Overall, dietary fat, dl-alpha-tocopherol acetate, and copper affected the oxidative status of pig muscles, and the results differed depending on muscle type.
Advances in channel‐adaptive video streaming (2002)

Abstract Despite the well‐known challenges of variations in throughput, delay, and packet loss over the Internet, video streaming has experienced phenomenal growth, owing to the extensive research in video coding and transmission. In this paper, we review several recent advances for channel‐adaptive video streaming that, we believe, will benefit the design of video streaming systems in the future. Employed in different components of the system, these techniques have the common objective of providing efficient, robust, scalable, and low‐latency streaming video. Firstly, by allowing the client to control the rate at which it consumes data, adaptive media playout can be used to reduce receiver buffering and therefore average latency, and provide limited rate scalability. Secondly, rate‐distortion optimized packet scheduling, a transport technique, provides a flexible framework to determine the best packet to send, given the channel behaviors, the packets' deadlines, their transmission histories, the distortion reduction associated with sending each packet, and the interpacket dependencies. Thirdly, at the source encoder, channel‐adaptive packet‐dependency control can greatly improve the error resilience of streaming video and reduce latency. Finally, we address the specific additional challenges for wireless video streaming. We consider three architectures for wireless video and discuss the utility of the reviewed techniques for each architecture. Copyright © 2002 John Wiley & Sons, Ltd.
A combined artificial neural network-fuzzy dynamic programming approach to reactive power/voltage control in a distribution substation (1998)

Reactive power/voltage control in a distribution substation is investigated in this work. The purpose is to determine proper capacitor on/off status and suitable load tap changer (LTC) positions for the 24 hours in the next day. To reach this goal, an artificial neural network (ANN) is designed to reach a preliminary dispatch schedule for the capacitor and LTC. The inputs to the ANN are main transformer real power and reactive power and primary and secondary bus voltages and the outputs are the desired capacitor on/off status and LTC tap positions. The preliminary dispatch schedule is further refined by fuzzy dynamic programming in order to reach the final schedule. To demonstrate the effectiveness of the proposed method, reactive power/voltage control is performed on a distribution substation in Taipei, Taiwan. Results from the example show that a proper dispatch schedule for capacitor and LTC can be reached by the proposed method in a very short period.
A New Type of Turnstile Antenna (2010)

This paper presents a new type of turnstile antenna, realized with two crossed dipoles connected in parallel. Feeding of the dipoles in phase quadrature to obtain an omnidirectional radiation pattern is achieved by optimizing their impedances to be complex conjugates. The dipoles are realized with aluminum strips. A balun - the transition from the antenna to a coaxial cable - is accomplished with lumped parameters: two capacitors and two inductors. The concept of the turnstile antenna presented can be used in the VHF and UHF frequency ranges. The measured results show very good agreement with those obtained by simulation. The antenna is also characterized by simple manufacturing and low cost.
Trace-metal adsorption characteristics of estuarine particulate matter: evaluation of contributions of iron/manganese oxide and organic surface coatings (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTrace-metal adsorption characteristics of estuarine particulate matter: evaluation of contributions of iron/manganese oxide and organic surface coatingsLeonard W. Lion, R. Scott. Altmann, and James O. LeckieCite this: Environ. Sci. Technol. 1982, 16, 10, 660–666Publication Date (Print):October 1, 1982Publication History Published online1 May 2002Published inissue 1 October 1982https://pubs.acs.org/doi/10.1021/es00104a007https://doi.org/10.1021/es00104a007research-articleACS PublicationsRequest reuse permissionsArticle Views985Altmetric-Citations258LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Tools and best practices for data processing in allelic expression analysis (2015)

Allelic expression analysis has become important for integrating genome and transcriptome data to characterize various biological phenomena such as cis-regulatory variation and nonsense-mediated decay. We analyze the properties of allelic expression read count data and technical sources of error, such as low-quality or double-counted RNA-seq reads, genotyping errors, allelic mapping bias, and technical covariates due to sample preparation and sequencing, and variation in total read depth. We provide guidelines for correcting such errors, show that our quality control measures improve the detection of relevant allelic expression, and introduce tools for the high-throughput production of allelic expression data from RNA-sequencing data.
Transfer to Rank for Top-N Recommendation (2019)

In this paper, we study top-N recommendation by exploiting users' explicit feedback such as 5-star numerical ratings, which has been overlooked to some extent in the past decade. As a response, we design a novel and generic transfer learning based recommendation framework coarse-to-fine transfer to rank (CoFiToR), which is a significant extension of a very recent work called transfer to rank (ToR). The key idea of our solution is modeling users' behaviors by simulating users' shopping processes. Therefore, we convert the studied ranking problem to three subtasks corresponding to three specific questions, including (i) whether an item will be examined by a user, (ii) how an item will be scored by a user, and (iii) whether an item will finally be purchased by a user. Based on this new conversion, we then develop a three-staged solution that progressively models users' preferences from a coarse granularity to a fine granularity. In each stage, we adopt an appropriate recommendation algorithm with pointwise or pairwise preference assumption to answer each question in order to seek an effective and efficient overall solution. Empirical studies on two large and public datasets showcase the merits of our solution in comparison with the state-of-the-art methods.