gebhart/patrepeval huggingface dataset:
The state of understanding of the lithium-ion-battery graphite solid electrolyte interphase (SEI) and its relationship to formation cycling (2016)

An in-depth historical and current review is presented on the science of lithium-ion battery (LIB) solid electrolyte interphase (SEI) formation on the graphite anode, including structure, morphology, composition, electrochemistry, and formation mechanism. During initial LIB operation, the SEI layer forms on the graphite surfaces, the most common anode material. The SEI is essential to the long-term performance of LIBs, and it also has an impact on its initial capacity loss, self-discharge characteristics, rate capability, and safety. While the presence of the anode SEI is vital, it is difficult to control its formation and growth, as they depend on several factors. These factors include the type of graphite, electrolyte composition, electrochemical conditions, and temperature. Thus, SEI formation and electrochemical stability over long-term operation should be a primary topic of future investigation in the LIB development. This article covers the progression of knowledge regarding the SEI, from its discovery in 1979 to the current state of understanding, and covers differences in the chemical and structural makeup when cell materials and components are varied. It also discusses the relationship of the SEI layer to the LIB formation step, involving both electrolyte wetting and subsequent slow charge–discharge cycles to grow the SEI.
Transcriptomic analysis of 3D Cardiac Differentiation of Human Induced Pluripotent Stem Cells Reveals Faster Cardiomyocyte Maturation Compared to 2D Culture (2019)

Human induced pluripotent stem cells (hiPSCs) represent an almost limitless source of cells for disease modelling and drug screening applications. Here we established an efficient and robust 3D platform for cardiomyocyte (CMs) production from hiPSCs, solely through small-molecule-based temporal modulation of the Wnt signalling, which generates more than 90% cTNT<sup>+</sup> cells. The impact of performing the differentiation process in 3D conditions as compared to a 2D culture system, was characterized by transcriptomic analysis by using data collected from sequential stages of 2D and 3D culture. We highlight that performing an initial period of hiPSC aggregation before cardiac differentiation primed hiPSCs towards an earlier mesendoderm lineage differentiation, via TGF-β/Nodal signaling stabilization. Importantly, it was also found that CMs in the 3D microenvironment mature earlier and show an improved communication system, which we suggested to be responsible for a higher structural and functional maturation of 3D cardiac aggregates.
Physical-Aware Memory BIST Datapath Synthesis: Architecture and Case-Studies on Complex SoCs (2011)

With increasing scaling, it is common to find large SoCs with more than 40M bits of embedded SRAMs constituting more than 75% of total die area [1]. Physical design for such complex SoCs with high speed memories pose numerous challenges for both functional and memory BIST logic. In this paper, we focus on generating physical aware correct-by-constuct memory BIST data path for first pass physical design closure.
A non-occluded, systemic baculovirus that occurs in cells of ectodermal and mesodermal origin and causes high mortality in the black tiger prawn Penaeus monodon (1995)

In the course of experimental infection of Penaeus monodon wlth yellow-head virus [YHV) for virus isolation and purification, 1 batch of prawns yielded hemolymph fractions dominated by a previously undescribed non-occluded baculovirus rather than YHV. Injection of test shrimp with a semipurified preparation of this virus gave rapid mortality, and examination with the transmission electron microscope revealed a dual infection where cells containing the new virus dominated, but some cells containing YHV could also be seen. The tissues infected by the 2 viruses were similar. However, in contrast to YHV, the new virus was assembled completely in the nucleus and in the absence of occluding protein (polyhedrin). By normal histology, the most characteristic feature of infection was eosinophilic Cowdry A-type inclusions in hypertrophied nuclei with marginated chromatin, especially in epithelial cells of the stomach. These intranuclear inclusions became lightly basophilic in late stages of infection. In the epithelial cells of the gills, ultrastructural pathology included nuclear hypertrophy and cytoplasmic disintegration leading to large voids at lysed cell sites. By negative staining, completely assembled, enveloped virions were ellipsoid to obovate with a distinctive multifibrillar appendage and they measured 276 x 121 nm (excluding the appendage). Enveloped and unenveloped nucleocapsids were significantly different In size, indicating posslble shortening and thickening of the viral core and nucleocapsid during viral assembly. Isolation and punficat~on of the nucleic acid from the new virus yielded double-stranded DNA of approximately 168 lulo base pairs. This DNA did not cross-hybridize with DNA fragments isolated from YHV-infected shrimp or from monodon baculovirus (MBV). The features placed t h ~s virus in the family Baculoviridae, subfamily Nudibaculovirinae as PmNOBII, but for convenience we have named it informally as Systemic Ectodermal and Mesodermal Baculovirus (SEMBV).
Thymidylate synthase gene expression in primary tumors predicts activity of s-1-based chemotherapy for advanced gastric cancer. (2007)

This study suggests that, via down-regulation of TS by irinotecan treatment, combination chemotherapy with S-1 and irinotecan could be effective in gastric cancer patients with high TS levels.
Update on the Hybrid Wireless Mesh Protocol of IEEE 802.11s (2007)

HWMP, the default routing protocol of IEEE 802.11s has been revised during the comment resolution of the first letter ballot. The paper gives an update on three areas where major changes have been introduced to HWMP: support for interworking with other networks; revised concept for proactive routing trees to root MPs; and a better aligned extensible path selection framework.
Paper-based triboelectric nanogenerators and their application in self-powered anticorrosion and antifouling (2016)

A paper-based triboelectric nanogenerator is fabricated by reusing gum wrappers as friction layers for self-powered anticorrosion and antifouling.
Efficient gradual segmentation of fingerprint images (2006)

Abstract:- A new algorithm for fingerprint image segmentation is presented. Gradual segmentation algorithm and multi segmentation features are used to segment fingerprint image in two steps. First we get the whole fingerprint region from image, and then the well-defined region and recoverable corrupted region are segmented from first step result. Region-growing method is introduced in first step to make the algorithm more robust. This algorithm can take more accurate segmentation for various types of images based on large numbers of the experiments. Key-words:- fingerprint segmentation; seed block; region-growing; gradual segmentation 1
ORIGINAL ARTICLE: Serial Estimation of Th1:Th2 Cytokines Profile in Women Undergoing <i>In‐Vitro</i> Fertilization‐Embryo Transfer (2008)

Women with a history of unexplained recurrent failed IVF treatment have a Th1 bias and this polarization is more enhanced following hormonal manipulations during IVF treatment. Comparing pre-treatment ratios of IFN-gamma:IL-4 and TNF-alpha:IL-4 to ratios obtained at oocyte retrieval may be clinically useful. Women with recurrent failed IVF have increasing ratios.
Homogeneously catalyzed synthesis of .beta.-amino alcohols and vicinal diamines from ethylene glycol and 1,2-propanediol (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHomogeneously catalyzed synthesis of .beta.-amino alcohols and vicinal diamines from ethylene glycol and 1,2-propanediolJohn A. MarsellaCite this: J. Org. Chem. 1987, 52, 3, 467–468Publication Date (Print):February 1, 1987Publication History Published online1 May 2002Published inissue 1 February 1987https://pubs.acs.org/doi/10.1021/jo00379a035https://doi.org/10.1021/jo00379a035research-articleACS PublicationsRequest reuse permissionsArticle Views996Altmetric-Citations45LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A Model Driven Framework to Compose Heterogeneous Services (2011)

In order to better comply to new requirements or quick adjustment with changing requirements, service composition is used in the way of exploiting the capability of available services. Service composition is one of the most benefits of SOA. Since emerging of RESTful web services, the needs for heterogeneous composition have been raised and brought up new challenges. On the other hand, service composition is a complex process. Therefore, to cope with all mentioned problems, a novel framework has been proposed in this paper. The aim of this framework is composing heterogeneous services semi automatically in a model driven fashion.
Antibody-Dependent Cell Cytotoxicity Synapses Form in Mice during Tumor-Specific Antibody Immunotherapy (2011)

Antibody-dependent cell cytotoxicity (ADCC) plays a critical role in monoclonal antibody (mAb)-mediated cancer therapy. ADCC, however, has not been directly shown in vivo but inferred from the requirement for IgG Fc receptors (FcγR) in tumor rejection in mice. Here, we investigated the mechanism of action of a Tn antigen-specific chimeric mAb (Chi-Tn), which binds selectively to a wide variety of carcinomas, but not to normal tissues, in both humans and mice. Chi-Tn mAb showed no direct toxicity against carcinomas cell lines in vitro but induced the rejection of a murine breast tumor in 80% to 100% of immunocompetent mice, when associated with cyclophosphamide. Tumor rejection was abolished in Fc receptors-associated γ chain (FcR-γ)-deficient mice, suggesting a role for ADCC. Indeed, tumor cells formed stable conjugates in vivo with FcR-γ chain-expressing macrophages and neutrophils in Chi-Tn mAb-treated but not in control mAb-treated mice. The contact zone between tumor cells and ADCC effectors accumulated actin, FcγR and phospho-tyrosines. The in vivo formed ADCC synapses were organized in multifocal supra-molecular activation clusters. These results show that in vivo ADCC mediated by macrophages and neutrophils during tumor rejection by Chi-Tn mAb involves a novel type of multifocal immune synapse between effectors of innate immunity and tumor cells.
Vanilloid receptors take a TRP beyond the sensory afferent☆ (2003)

Departments of Biological Chemistry and Neuroscience, Johns Hopkins School of Medicine, Baltimore, MD, USA *Tel.: +410-502-5457 E-mail address:[email protected] Submitted and accepted June 9, 2003. ☆Supported by The American Cancer Society (RSG-01-063-01-CSM).
Uptake of fluorescence-labeled dextrans by 10T 1/2 fibroblasts following permeation by rectangular and exponential-decay electric field pulses. (1988)

The uptake of fluorescence-labeled dextrans by adherent 10T 1/2 murine fibroblasts following electric field pulse application was used as a criterion for the efficiency of electropermeation. The cells in monolayers were permeated by immersing a coaxial electrode in culture dishes. The percentage of cells which exhibited fluorescence uptake following electric field pulse application was measured at independently varying pulse field strength and pulse length. Dextrans with molecular weights equal to or higher than 41,000 dalton require higher field strength or longer pulse time to penetrate the cells. There is no detectable advantage of using a rectangular pulse against using an exponential decay pulse of similar power. The uptake was proportional to the product of the pulse amplitude and duration over the experimental range of 40-950 microseconds and 0.1-14.5 kV/cm. Cell survival decreases at the upper end of this range. The result provides a direct comparison of electric parameters which so far have not been standardized with regard to cell electropermeation.
SLUG Microwave Amplifier: Theory (2011)

We describe a novel scheme for low-noise phase-insensitive linear amplification at microwave frequencies based on the Superconducting Low-inductance Undulatory Galvanometer (SLUG). Direct integration of the junction equations of motion provides access to the full scattering matrix of the SLUG. We discuss the optimization of SLUG amplifiers and calculate amplifier gain and noise temperature in both the thermal and quantum regimes. Loading of the SLUG element by the finite input admittance is taken into account, and strategies for decoupling the SLUG from the higher-order modes of the input circuit are discussed. The microwave SLUG amplifier is expected to achieve noise performance approaching the standard quantum limit in the frequency range from 5-10 GHz, with gain around 15 dB for a single-stage device and instantaneous bandwidths of order 1 GHz.
Does activation of the FcγRIIa play a role in the pathogenesis of the acute lung injury/acute respiratory distress syndrome? (2010)

ALI (acute lung injury) and its more severe form ARDS (acute respiratory distress syndrome) are inflammatory diseases of the lung characterized by hypoxaemia and diffuse bilateral infiltrates. Disruption of epithelial integrity and injury to endothelium are contributing factors of the development of ALI/ARDS, and alveolar damage is the most pronounced feature of ALI/ARDS. The resulting increase in lung microvascular permeability promotes influx of inflammatory cells to the alveolar spaces. Oedema fluid contains pro-nflammatory mediators and plasma proteins, including Igs (immunoglobulins). Moreover, several reports describe the presence of autoantibodies and immune complexes [anti-IL-8 (interleukin-8) autoantibody/IL-8 complexes] in lung fluids (oedema and bronchoalveolar lavage fluids) from patients with ALI/ARDS. These immune complexes associate with FcgammaRIIa (Fcgamma IIa receptor) in lungs of patients with ARDS. Furthermore, the expression of FcgammaRIIa is substantially elevated in lungs of these patients. FcgammaRIIa appears on virtually all myeloid cells, platelets and endothelial cells. It is a low-affinity receptor for IgG that preferentially binds aggregated immunoglobulins and immune complexes. FcgammaRs regulate phagocytosis and cell-mediated cytotoxicity, and initiate the release of inflammatory mediators. It should be noted that immune complexes formed between either anti-neutrophil autoantibodies and their specific antigens or anti-HLA (human leucocyte antigen) antibodies and target antigens are implicated in the pathogenesis of TRALI (transfusion-related acute lung injury), and importantly, animal studies indicate that FcgammaRs are essential for these complexes to cause damage to the lungs. Therefore, we hypothesize that FcgammaRs such as FcgammaRIIa could contribute to the pathogenesis of ALI/ARDS.
Fabrication and characterization of HfC coated Si field emitter arrays (2003)

We fabricated hafnium carbide (HfC) coated Si field emitter arrays (HfC FEAs) with an extraction-gate electrode to improve the emission characteristics of Si FEAs. Hafnium carbide thin film was deposited by inductively coupled plasma-assisted magnetron sputtering. The HfC film was characterized by x-ray photoelectron spectroscopy and x-ray diffraction measurement, and was found to be (111)-oriented polycrystalline film. The HfC FEAs exhibited superior performance. An emission of more than 10 mA could be obtained from the 16 000 tip array, which is 20 times higher than that for Si FEAs. The operational voltage for emission of 1 μA decreased from 61 to 45 V due to the HfC coating. The long-term emission characteristics were also measured. Si FEAs degraded rapidly even in an ultrahigh vacuum chamber. However, the emission degradation in the HfC FEAs was much slower. The number of active tips was counted using an electrostatic-lens projector, and the results revealed that the HfC FEAs had six times as many tips as the Si FEAs had.
Experimental bovine respiratory syncytial virus infection in conventional calves: Light microscopic lesions, microbiology, and studies on lavaged lung cells (1985)

Conventionally raised male Holstein calves, 1 month of age, were infected by intranasal and intratracheal inoculation with bovine respiratory syncytial virus. Viral antigen was identified by fluorescence microscopy most commonly in the cytoplasm of tracheal and bronchial epithelial cells 3 to 5 days after inoculation. Cytoplasmic viral antigen was identified also in nasal, nasopharyngeal, bronchiolar, and alveolar epithelial cells and in alveolar macrophages. Bronchitis and tracheitis, characterized in part by epithelial necrosis, formation of syncytial epithelial cells and epithelial hyperplasia, were the most common lesions observed histologically. Rhinitis, bronchiolitis, and interstitial pneumonia were observed less frequently. Alterations were not detected in the numbers of cells recovered by bronchoalveolar lavage after inoculation. An increase in the phagocytic rate of latex beads occurred in macrophages 5 days after inoculation. Viral-induced lesions were resolved by 30 days after inoculation. The results indicated that bovine respiratory syncytial virus inoculation of calves results in reversible alterations in airway epithelial structure and in the phagocytic function of alveolar macrophages.
Adaptive Top-k Algorithm in SLCA-Based XML Keyword Search (2010)

Computing top-k results matching XML queries is gaining importance due to the increasing of large XML repositories. In this paper, we propose a novel two-layer-based index construction and associated algorithms for efficiently computing top-k results for SLCA-based XML keyword search. We have conducted expensive experiments and the results show great advantage on efficiency compared with existing approaches.
Digital bas-relief from 3D scenes (2007)

We present a system for semi-automatic creation of bas-relief sculpture. As an artistic medium, relief spans the continuum between 2D drawing or painting and full 3D sculpture. Bas-relief (or low relief) presents the unique challenge of squeezing shapes into a nearly-flat surface while maintaining as much as possible the perception of the full 3D scene. Our solution to this problem adapts methods from the tone-mapping literature, which addresses the similar problem of squeezing a high dynamic range image into the (low) dynamic range available on typical display devices. However, the bas-relief medium imposes its own unique set of requirements, such as maintaining small, fixed-size depth discontinuities. Given a 3D model, camera, and a few parameters describing the relative attenuation of different frequencies in the shape, our system creates a relief that gives the illusion of the 3D shape from a given vantage point while conforming to a greatly compressed height.
cDNA Cloning and Characterization of a Cek7 Receptor Protein-tyrosine Kinase Ligand That Is Identical to the Ligand (ELF-1) for the Mek-4 and Sek Receptor Protein-tyrosine Kinases (1995)

We have isolated a murine cDNA encoding a ligand for the Cek7 receptor protein-tyrosine kinase (RPTK), a member of the Eph/Eck RPTK subfamily. Sequence analysis predicts an open reading frame of 209 amino acids with a predicted molecular mass of 24 kDa. The Cek7 ligand shows a 48% sequence identity at the protein level to B61, a ligand for the related Eck RPTK, 30% to the Cek5 ligand, 59% to the recently cloned Ehk1-L, and identity to ELF-1, a recently described ligand for the Mek4 and Sek RPTKs. The expressed Cek7 ligand is functionally active as it induces autophosphorylation of the Cek7 RPTK.
Quantitative comparison of OSEM and penalized likelihood image reconstruction using relative difference penalties for clinical PET (2015)

Ordered subset expectation maximization (OSEM) is the most widely used algorithm for clinical PET image reconstruction. OSEM is usually stopped early and post-filtered to control image noise and does not necessarily achieve optimal quantitation accuracy. As an alternative to OSEM, we have recently implemented a penalized likelihood (PL) image reconstruction algorithm for clinical PET using the relative difference penalty with the aim of improving quantitation accuracy without compromising visual image quality. Preliminary clinical studies have demonstrated visual image quality including lesion conspicuity in images reconstructed by the PL algorithm is better than or at least as good as that in OSEM images. In this paper we evaluate lesion quantitation accuracy of the PL algorithm with the relative difference penalty compared to OSEM by using various data sets including phantom data acquired with an anthropomorphic torso phantom, an extended oval phantom and the NEMA image quality phantom; clinical data; and hybrid clinical data generated by adding simulated lesion data to clinical data. We focus on mean standardized uptake values and compare them for PL and OSEM using both time-of-flight (TOF) and non-TOF data. The results demonstrate improvements of PL in lesion quantitation accuracy compared to OSEM with a particular improvement in cold background regions such as lungs.
What we don’t (but should) know about hydrocephalus (2006)

In an effort to identify critical gaps in the prevailing knowledge of hydrocephalus, the authors formulated 10 key questions. 1) How do we define hydrocephalus? 2) How is cerebrosinal fluid (CSF) absorbed normally and what are the causes of CSF malabsorption in hydrocephalus? 3) Why do the ventricles dilate in communicating hydrocephalus? 4) What happens to the structure and function of the brain when it is compressed and stretched by the expanding ventricles? 5) What is the role of cerebrovenous pressure in hydrocephalus? 6) What causes normal-pressure hydrocephalus? 7) What causes low-pressure hydrocephalus? 8) What is the pathophysiology of slit ventricle syndrome? 9) What is the pathophysiological basis for neurological impairment in hydrocephalus, and to what extent is it reversible? 10) How is the brain of a child with hydrocephalus different from that of a young or elderly adult? Rigorous answers to these questions should lead to more effective and reliable treatments for this disorder.