gebhart/patrepeval huggingface dataset:
Nucleotide sequence of a crustacean 18S ribosomal RNA gene and secondary structure of eukaryotic small subunit ribosoraal RNAs (1984)

The primary structure of the gene for 18 S rRNA of the crustacean Artemia salina was determined. The sequence has been aligned with 13 other small ribosomal subunit RNA sequences of eukaryotic, archaebacterial, eubacterial, chloroplastic and plant mitochondrial origin. Secondary structure models for these RNAs were derived on the basis of previously proposed models and additional comparative evidence found in the alignment. Although there is a general similarity in the secondary structure models for eukaryotes and prokaryotes, the evidence seems to indicate a different topology in a central area of the structures.
The application of factorization machines in user behavior prediction (2016)

With the development of Internet, shopping on the internet is becoming more and more popular. In the meantime, the massive commodity make the experience of online shopping bad. In order to solve this problem, commodity recommendation system is applied into e-commerce platform and the experience of online shopping has been promoted. Essentially, commodity recommendation is a kind of behavior prediction. So, research on user behavior prediction can also promote experience of online shopping. In this paper, the FMs algorithm is applied into prediction of user behavior. Based on real data of user behavior data, we take advantage of four kinds of behavior to make analysis and propose a good user behavior prediction model based on FMs algorithm.
Chemokines and chemokine receptors in renal transplantation — from bench to bedside (2007)

Attraction of mononuclear cells to sites of inflammation requires a close interplay of the inflammatory signal presented via chemokines and specific receptors on effector cells. First studies on acute renal transplant rejection demonstrated the involvement of CC-chemokines, such as RANTES, MIP-1alpha, MIP-1beta and MCP-1, as well as CXC-chemokines such as IL-8 and IP-10, correlating with expression of the corresponding chemokine receptors, CCR1, CCR5 and CCR2 as well as CXCR3. Since then, the pathophysiologic relevance has been extended to chronic allograft nephropathy and transplant glomerulopathy. Chemokine expression can be triggered by different stimuli, e.g. brain death, ischemia, HLA-mismatch and infection. Furthermore, anti-inflammatory chemokines have been identified. Chemokine receptor 7, e.g. enhances homing of lymphocytes to lymphatic tissues and the Duffy antigen receptor, DARC, a non-specific receptor that binds and inactivates different chemokines. While measurement of chemokine expression in clinical transplantation may facilitate the differential diagnosis of allograft dysfunction, knowledge of the chemokine network has also widened the understanding of transplant rejection and opened novel therapeutic approaches. Observations from humans with mutations of the chemokine network as well as transplantation of animals with targeted deletions in this system suggest that manipulations of chemokine signalling may improve the success rates of transplantation. Blocking chemokines unselectively with Met-RANTES or specifically with small molecule inhibitors of various chemokine receptors has lead to improved outcome in animal models. Currently, first human trials are under way to investigate drugs that stimulate lymphocyte homing. Inhibitors of CCR1 and CCR5 are being tested for other human diseases and may eventually be available in transplantation. Nonetheless, chemokine blockade my rather serve as an adjunct in the management of transplant recipients than a new "magic bullet".
Comprehensive characterization of the site-specific N-glycosylation of wild-type and recombinant human lactoferrin expressed in the milk of transgenic cloned cattle (2010)

The glycosylation profile of a recombinant protein is important because glycan moieties can play a significant role in the biological properties of the glycoprotein. Here we determined the site-specific N-glycosylation profile of human lactoferrin (hLF) and recombinant human lactoferrin (rhLF) expressed in the milk of transgenic cloned cattle. We used combined approaches of monosaccharide composition analysis, lectin blot, glycan permethylation and sequential exoglycosidase digestion and analyzed samples using high-performance ion chromatography and mass spectrometry (MS). N-glycans from hLF are comprised entirely of highly branched, highly sialylated and highly fucosylated complex-type structures, and many contain Lewis(x) epitopes. Six of these structures are reported here for the first time. However, N-glycans from rhLF are of the high mannose-, hybrid- and complex-type structures, with less N-acetylneuraminic acid and fucose. Some contain a terminal N-acetylgalactosamine-N-acetylglucosamine (LacdiNAc) disaccharide sequence. Monosaccharide composition analysis of rhLF revealed small amounts of N-glycolylneuraminic acid, which were not detected by MS. hLF and rhLF appear to be glycosylated at the same two sites: Asn138 and Asn479. The third putative glycosylation site, at Asn624, is unglycosylated in both hLF and rhLF. The relative abundance of each N-glycan at each site was also determined. The different N-glycosylation profile of rhLF when compared with that of hLF is in consistent with the widely held view that glycosylation is species- and tissue/cell-specific. These data provide an important foundation for further studies of glycan structure/function relationships for hLF and rhLF and help to better understand the glycosylation mechanism in bovine mammary epithelial cells.
Analysis of the Interactions Between Piperacillin, Ticarcillin, or Carbenicillin and Aminoglycoside Antibiotics (1978)

Enhanced activity against clinical isolates of Pseudomonas aeruginosa was demonstrated with piperacillin, ticarcillin, and carbenicillin in combination with gentamicin, tobramycin, and amikacin.
Electrical transport through 60 base pairs of poly(dG)-poly(dC) DNA molecules (2002)

We report electrical transport through 60 base pairs of poly(dG)-poly(dC) DNA molecules. The DNA solution is dropped on two metal electrodes with the gap of 20 nm. The current–voltage characteristics measured between the electrodes exhibits clear staircases, which are reproducible over repeated measurements. The size of the observed staircases is consistent with the energy gap obtained from a tight binding calculation.
Effects of C/Si Ratio in Chemical Vapor Deposition of 4H-SiC(11\bar20) and (03\bar38) (2003)

Homoepitaxial growth of 4H-SiC(1120) and (0338) by hot-wall chemical vapor deposition has been investigated. Both the residual-donor concentration and deep-level concentrations can be reduced by increasing the C/Si ratio during growth. The optimum C/Si ratio for obtaining high-quality epilayers with good morphology is higher on the non-basal planes than on off-axis (0001). The correlation between deep levels and growth condition is discussed.
Study on the Physical and Mechanical Properties of Al-Powder Reinforced Bioactive Glass: Ceramic Composite Material (2022)

Glass-ceramic samples, having composition of SiO2-35, CaO-45, Na2O-10 and P2O5-10 in weight ratio were prepared through sintering route. Glass powder was reinforced by Al powder. The strength of glass-ceramic composite was found to be temperature dependent, and it varies with the addition of Al powder. Flexural strength increases with the increase of powder addition and sintering temperature, however, decreases with the increase of sintering time. There is an optimum temperature (>1100℃) above which flexural strength of all samples decreases. Bulk density changes to a higher value as the addition of Al-powder increases up to 3% by weight above which density decreases slowly. On the other hand, apparent porosity and water absorption decrease with the increase of percentage of Al powder added. Porosity and water absorption also showed a dependent characteristic on sintering time and sintering temperature.
Low density parity check codes for the relay channel (2007)

We propose Low Density Parity Check (LDPC) code designs for the half-duplex relay channel. Our designs are based on the information theoretic random coding scheme for decode-and-forward relaying. The source transmission is decoded with the help of side information in the form of additional parity bits from the relay. We derive the exact relationships that the component LDPC code profiles in the relay coding scheme must satisfy. These relationships act as constraints for the density evolution algorithm which is used to search for good relay code profiles. To speed up optimization, we outline a Gaussian approximation of density evolution for the relay channel. The asymptotic noise thresholds of the discovered relay code profiles are a fraction of a decibel away from the achievable lower bound for decode-and-forward relaying. With random component LDPC codes, the overall relay coding scheme performs within 1.2 dB of the theoretical limit.
Genomics and epidemiology of a novel SARS-CoV-2 lineage in Manaus, Brazil (2021)

Cases of SARS-CoV-2 infection in Manaus, Brazil, resurged in late 2020, despite high levels of previous infection there. Through genome sequencing of viruses sampled in Manaus between November 2020 and January 2021, we identified the emergence and circulation of a novel SARS-CoV-2 variant of concern, lineage P.1, that acquired 17 mutations, including a trio in the spike protein (K417T, E484K and N501Y) associated with increased binding to the human ACE2 receptor. Molecular clock analysis shows that P.1 emergence occurred around early November 2020 and was preceded by a period of faster molecular evolution. Using a two-category dynamical model that integrates genomic and mortality data, we estimate that P.1 may be 1.4-2.2 times more transmissible and 25-61% more likely to evade protective immunity elicited by previous infection with non-P.1 lineages. Enhanced global genomic surveillance of variants of concern, which may exhibit increased transmissibility and/or immune evasion, is critical to accelerate pandemic responsiveness.
Role of components in the formation of self-microemulsifying drug delivery systems (2015)

Pharmaceutical research is focused in designing novel drug delivery systems to improve the bioavailability of poorly water soluble drugs. Self-microemulsifying drug delivery systems, one among the lipid-based dosage forms were proven to be promising in improving the oral bioavailability of such drugs by enhancing solubility, permeability and avoiding first-pass metabolism via enhanced lymphatic transport. Further, they have been successful in avoiding both inter and intra individual variations as well as the dose disproportionality. Aqueous insoluble drugs, in general, show greater solubility in lipid based excipients, and hence they are formulated as lipid based drug delivery systems. The extent of solubility of a hydrophobic drug in lipid excipients i.e. oil, surfactant and co-surfactant (components of self-microemulsifying drug delivery systems) greatly affects the drug loading and in producing stable self-microemulsifying drug delivery systems. The present review highlighted the influence of physicochemical factors and structural features of the hydrophobic drug on its solubility in lipid excipients and an attempt was made to explore the role of each component of self-microemulsifying drug delivery systems in the formation of stable microemulsion upon dilution.
<title>Vision-based semi-autonomous outdoor robot system to reduce soldier workload</title> (2001)

Sensors and computational capability have not reached the point to enable small robots to navigate autonomously in unconstrained outdoor environments at tactically useful speeds. This problem is greatly reduced, however, if a soldier can lead the robot through terrain that he knows it can traverse. An application of this concept is a small pack-mule robot that follows a foot soldier over outdoor terrain. The solder would be responsible to avoid situations beyond the robot's limitations when encountered. Having learned the route, the robot could autonomously retrace the path carrying supplies and munitions. This would greatly reduce the soldier's workload under normal conditions. This paper presents a description of a developmental robot sensor system using low-cost commercial 3D vision and inertial sensors to address this application. The robot moves at fast walking speed and requires only short-range perception to accomplish its task. 3D-feature information is recorded on a composite route map that the robot uses to negotiate its local environment and retrace the path taught by the soldier leader.
Rhenium‐Catalyzed Deoxydehydration of Diols and Polyols (2014)

The substitution of platform chemicals of fossil origin by biomass-derived analogues requires the development of chemical transformations capable of reducing the very high oxygen content of biomass. One such reaction, which has received increasing attention within the past five years, is the rhenium-catalyzed deoxydehydration (DODH) of a vicinal diol into an alkene; this is a model system for abundant polyols like glycerol and sugar alcohols. The present contribution includes a review of early investigations of stoichiometric reactions involving rhenium, diols, and alkenes followed by a discussion of the various catalytic systems that have been developed with emphasis on the nature of the reductant, the substrate scope, and mechanistic investigations.
On the performance of MIMO RFID backscattering channels (2012)

In order to increase the reliability of data transmission, using multiple antennas in radio frequency identification (RFID) systems has been investigated by researchers, mainly through measurements and simulations. The multiple-input multiple-output (MIMO) RFID backscattering channel exhibits a special type of cascaded structure rather than that of other better-studied cascaded channels such as the keyhole fading and the double scattering fading. In this article, we analytically study the bit error rate performances of the MIMO RFID channel under two transmission schemes, the identical signaling transmission scheme and the orthogonal space-time coding scheme (OSTBC). We show that the diversity order of the MIMO RFID channel is min(N, L) under the identical transmission scheme, and the diversity order is L under the OSTBC scheme, where L is the number of tag antennas and N is the number of reader receiving antennas. A performance bottleneck is also observed in the MIMO RFID channel. Our results can provide useful guidance on designing an RFID system with multiple antennas.
Bespoke control software and quality (HVAC systems) (1990)

The availability of low cost microprocessor-based controllers for energy management has enabled strategies for control of HVAC plant to become more and more complex. However, the plant to be controlled and therefore the strategy required, varies significantly from installation to installation. Some means of effectively adapting the control system to the specific application is therefore required. There are currently two industry-standard solutions to the problem. One uses a high level programming language, specially developed for writing control programs, whereas the other uses a graphical representation of the control strategy to show how data will flow from one pre-defined software module to another. This paper examines how computer-aided design techniques (the latter sort of software development) can be used to facilitate the programming of a controlling outstation. It also shows how quality control is aided by such an approach.
Nearly-off-axis transmissivity of Solc birefringent filters (2003)

The characteristics of light propagating near the axis of a birefringent filter are studied. A generalized formulation to describe the nearly-off-axis transmissivity of a Solc birefringent filter is derived. On this basis, the polarization conoscopic figures of Solc filters with different numbers of birefringent plates are simulated. Furthermore the variation of spectral transmission with angle of incidence is analyzed, and the field-of-view transmissivity and the spectral transmissivity averaged with respect to the spread of incident light are given. Primary experiments for verification are also demonstrated.
Infectious Diseases in Disaster (1991)

The danger posed by communicable diseases in post disaster situation is much less compared to the popular belief, which can be attributed to effective counter measures. The responsible management of disaster relief should include consideration of the establishment of a surveillance system and the institution of appropriate sanitary and medical measures to counter the elements, which can contribute to the transmission of disease.
The relative dietary importance of haem and non-haem iron. (1983)

A study was undertaken to find out the relative amounts of haem and non-haem iron absorbed from meals in which varying amounts of these substances were present. Four meals, each containing 6 mg of iron but with varying ratios of haem and non-haem iron, were fed to two groups of subjects, each group receiving two meals. The geometric mean percentage absorption of non-haem iron decreased from 18.0% (SD range 14.6-22.3%) to 6.4% (SD range 3.4-11.8%) as the non-haem iron content of the meal increased from 1.52 mg to 5.72 mg--there was therefore little variation in the actual amounts of non-haem iron absorbed from the different meals. In contrast, the geometric mean absorption of haem iron was approximately 20% from all four meals, although the haem iron content varied between 0.28 mg and 4.48 mg. The amount of haem iron absorbed was thus a linear function of the amount of haem iron in the meal. Two points emerged from the study. Firstly, the relative importance of haem iron in overall iron nutrition was confirmed. Secondly, the fact that the pattern of absorption in relation to dosage was so different for haem iron and non-haem iron suggested that a controlling mechanism for non-haem iron absorption may be located at the mucosal surface. This conclusion is based on the fact that haem iron, the percentage absorption of which was found to be independent of the size of the dose, is absorbed into the mucosal cell when still contained within the porphyrin ring and the iron thus bypasses some controlling mechanism at the mucosal border.
Prognostic Significance of BACH2 Expression in Diffuse Large B-Cell Lymphoma: A Study of the Osaka Lymphoma Study Group (2005)

Purpose BACH2, a B-cell–specific transcription repressor, is abundantly expressed in lymphocytes of B-cell lineage as well as B-cell lymphoma cell lines. BACH2 possesses an inhibitory effect on proliferation of Raji cell lines derived from Burkitt's lymphoma. In this study, the prognostic significance of BACH2 expression was examined in diffuse large B-cell lymphoma (DLBCL). Patients and Methods BACH2 expression was immunohistochemically examined on the paraffin-embedded sections obtained by biopsy from 108 patients (62 males and 46 females; age range, 23 to 85 years) with DLBCL. Staining intensity in the cytoplasm of the tumor cells was categorized as equal to or stronger (level 1) or weaker (level 2) than that in the endothelial cells in the same specimens. Results Level 1 and 2 expression of BACH2 was found in 32.4% and 67.6% of patients, respectively. Patients with level 1 expression showed significantly better disease-free and overall survival rate than those with level 2 expression (both P < .05). Multivariate analysis revealed BACH2 expression level together with performance status, elevated serum level of lactate dehydrogenase, and treatment response to be independent factors for prognosis of the patients. Conclusion BACH2 expression level is a useful marker to predict disease-free and overall survival of patients with DLBCL.
Falls and Fractures (2009)

Why did I fall? Older people’s perceptions of the cause of their fall predict outcomes at 6 month
Correction: Lim, S., et al. Millimeter-Wave Chemical Sensor Using Substrate-Integrated-Waveguide Cavity. Sensors 2016, 16, 1829 (2016)

n/a.
Thromboxane A2 biosynthesis in human disease. (1987)

Thromboxane A2 (TxA2), the predominant cyclooxygenase product of human platelets, is a potent vasoconstrictor and platelet agonist. Although its biological properties are readily appreciable in vitro, it has been difficult to define its biological importance in vivo. To a large extent this reflected the problems associated with efforts to monitor biosynthesis of this eicosanoid and the lack of selective pharmacological probes that prevented the synthesis of TxA2 or antagonized its biological action in vivo. Recently the analysis of urinary metabolites of TxB2 has become simplified so that the methodology is readily applicable to clinical studies. This provides a noninvasive, time-integrated index of Tx biosynthesis. Although one cannot definitively establish a tissue of origin for metabolites measured in urine, indirect evidence suggests that urinary TxB2 derives primarily from the kidney whereas its dinor metabolite predominantly reflects platelet biosynthesis under physiological conditions. Although plasma concentrations of TxB2 are readily confounded by platelet activation ex vivo, the enzymatic metabolites formed from TxB2 have recently been identified and appear to bypass this problem. Combined analysis of long-lived (e.g., 11-dehydro-TxB2) and short-lived (e.g., 2,3-dinor-TxB2) metabolites in plasma promise to more accurately localize phasic increases in the biosynthesis of TxA2 and have been paralleled by the development of antagonists of the TxA2/prostaglandin endoperoxide receptor and their study of humans. The use of such specific probes in conditions characterized by abnormal biosynthesis of TxA2 promises to define the biological role of this mediator for humans.
A near unity power factor input stage with minimum control requirements for AC drive applications (2002)

Conventional AC induction motor drives use PWM voltage source inverter (VSI) fed from a diode rectifier. In retrofit applications, due to voltage drops and the inverter voltage gain, six-step operation of the inverter is required at rated speed, resulting in large low order harmonic current and torque components. To allow the inverter to operate in the PWM mode of rated speed, a synchronous rectifier is used in this paper to boost the DC bus voltage slightly. The resulting converter system presents all the advantages associated with active front-end rectifiers. However, since the DC bus control requirements are not stringent, a simple control structure is used to ensure unity power factor operation. Furthermore, optimized PWM patterns and pattern synchronization are used to reduce the switching frequency of the rectifier. The paper presents an analysis and design guidelines for the complete drive system. Simulation and experimental results on a 5 kVA induction motor drive confirm the feasibility and advantages of the proposed structure.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
四角い家の秘密 : casa cube (2009)

１ 四角い家ｃａｓａ ｃｕｂｅ誕生 ２ ｃａｓａ ｃｕｂｅはなぜ高品質で低価格なのか ３ ｃａｓａ ｃｕｂｅはなぜ選ばれるのか ４ ｃａｓａ ｃｕｂｅが住みやすい理由—仕様 ５ ｃａｓａ ｃｕｂｅの間取り集 ６ 私がｃａｓａ ｃｕｂｅを選んだ理由 ７ ｃａｓａ ｃｕｂｅのことをもっと知りたい人のためのＱ＆Ａ
Constant Space Complexity Environment Representation for Vision-based Navigation (2017)

This paper presents a preliminary conceptual investigation into an environment representation that has constant space complexity with respect to the camera image space. This type of representation allows the planning algorithms of a mobile agent to bypass what are often complex and noisy transformations between camera image space and Euclidean space. The approach is to compute per-pixel potential values directly from processed camera data, which results in a discrete potential field that has constant space complexity with respect to the image plane. This can enable planning and control algorithms, whose complexity often depends on the size of the environment representation, to be defined with constant run-time. This type of approach can be particularly useful for platforms with strict resource constraints, such as embedded and real-time systems.