gebhart/patrepeval huggingface dataset:
CULTURA ALEMÃ E TEUTO-BRASILEIRA EM TERRAS MINEIRAS: A HISTÓRIA DO TURNERSCHAFT-CLUB GYMNASTICO (1909-1979) (2015)

O objetivo deste trabalho e analisar historicamente um dos primeiros clubes de ginastica de Minas Gerais, fundado em 1909 na cidade de Juiz de Fora. Este recebeu inicialmente, o nome de Turnerschaft-Club Gymnastico por ser uma instituicao baseada, quando de sua fundacao, nos preceitos difundidos pela cultura alema, materializada nas atividades ginasticas preconizadas principalmente pelo alemao Friederich Ludwig Jahn. Foi um Clube Ginastico de grande representatividade na cidade chegando a ter em media 1000 associados na decada de 1940. Percebemos que esta instituicao foi uma grande incentivadora do esporte na cidade, divulgando principalmente atividades como a ginastica, basquetebol, atletismo e voleibol em um periodo em que estes esportes ainda nao eram tao praticados e conhecidos na cidade. Fechado em 1979, por diferentes motivos, deixou para tras uma importante historia de vitorias e conquistas alem de uma importante influencia para a historia esportiva de Juiz de Fora e assim na formacao de um cenario esportivo caracteristico da cidade de hoje. Palavras-Chave : Turnerschaft; Ginastica; Esporte. Abstract : The objective of this study is to analyze historically one of the first fitness centers of Minas Gerais, established in 1909 in the city of Juiz de Fora. This initially received, the name of Turnerschaft-Club Gymnastico to be a based institution when it was founded, the precepts broadcast by German culture, embodied in gymnastics activities mainly advocated by the German Friedrich Ludwig Jahn. It was a gymnastic club great representation in the city coming to have on average in 1000 associated in the 1940s realized that this institution was a great incentive the sport in the city, mainly disseminating activities such as gymnastics, basketball, volleyball and athletics at a time that these sports were not as practiced and known in the city. Closed in 1979, for different reasons, left behind an important history of victories and achievements as well as an important influence on the sporting history of Juiz de Fora and thus the formation of a characteristic sports scene of today's city. Keywords : Turnerschaft; Gym; Sport.
Matrix Metalloproteinase Processing of CXCL11/I-TAC Results in Loss of Chemoattractant Activity and Altered Glycosaminoglycan Binding (2008)

The CXCR3 chemokine receptor regulates the migration of Th1 lymphocytes and responds to three ligands: CXCL9/MIG, CXCL10/IP-10, and CXCL11/I-TAC. We screened for potential regulation of T cell responses by matrix metalloproteinase (MMP) processing of these important chemokines. The most potent of the CXCR3 ligands, CXCL11, was identified by matrix-assisted laser desorption ionization time-of-flight mass spectrometry as a substrate of the PMN-specific MMP-8, macrophage-specific MMP-12, and the general leukocyte MMP-9. The 73-amino acid residue CXCL11 is processed at both the amino and carboxyl termini to generate CXCL11-(5-73), -(5-63), and -(5-58) forms. NH2-terminal truncation results in loss of agonistic properties, as shown in calcium mobilization and chemotaxis experiments using CXCR3 transfectants and human T lymphocytes. Moreover, CXCL11-(5-73) is a CXCR3 antagonist and interestingly shows enhanced affinity to heparin. However, upon COOH-terminal truncation to position 58 there is loss of antagonist activity and heparin binding. Together this highlights an unexpected site for receptor interaction and that the carboxyl terminus is critical for glycosaminoglycan binding, an essential function for the formation of chemokine gradients in vivo. Hence, MMP activity might regulate CXCL11 tissue gradients in two ways. First, the potential of CXCL11-(5-73) to compete active CXCL11 from glycosaminoglycans might lead to the formation of an antagonistic haptotactic chemokine gradient. Second, upon further truncation, MMPs disperse the CXCL11 gradients in a novel way by proteolytic loss of a COOH-terminal GAG binding site. Hence, these results reveal potential new roles in down-regulating Th1 lymphocyte chemoattraction through MMP processing of CXCL11.
Magnesium Borohydride Complexed by Tetramethylethylenediamine (2007)

A complex of magnesium borohydride, Mg(BH4)2.Me2NC2H4NMe2, has been synthesized and structurally characterized. This monomer complex has a pseudotetrahedral geometry around the Mg atom with tridentate BH4 groups and short Mg...B distances.
Phase-extraction analysis of laser-diode phase-shifting interferometry that is insensitive to changes in laser power (1996)

We investigate phase-shifting interferometry with a laser diode that is insensitive to changes in laser power associated with variations in current. A phase-extraction algorithm is newly developed in which the tested phase from six interferograms is measured. A formulation of the algorithm is presented by a least-squares fitting of the interference fringes to the function of the interferogram that includes intensity variations produced by changes in laser power. The performance of the algorithm is compared with the technique of Fourier analysis. A phase error caused by the power change of the laser diode is analyzed theoretically by use of the conventional phase-measurement algorithm and the Fourier-analysis technique. The systematic error is numerically investigated in comparison with the experimental result. A good agreement between them is shown.
ROCK Inhibitor Enhances Adhesion and Wound Healing of Human Corneal Endothelial Cells (2013)

Maintenance of corneal transparency is crucial for vision and depends mainly on the endothelium, a non-proliferative monolayer of cells covering the inner part of the cornea. When endothelial cell density falls below a critical threshold, the barrier and "pump" functions of the endothelium are compromised which results in corneal oedema and loss of visual acuity. The conventional treatment for such severe disorder is corneal graft. Unfortunately, there is a worldwide shortage of donor corneas, necessitating amelioration of tissue survival and storage after harvesting. Recently it was reported that the ROCK inhibitor Y-27632 promotes adhesion, inhibits apoptosis, increases the number of proliferating monkey corneal endothelial cells in vitro and enhance corneal endothelial wound healing both in vitro and in vivo in animal models. Using organ culture human cornea (N = 34), the effect of ROCK inhibitor was evaluated in vitro and ex vivo. Toxicity, corneal endothelial cell density, cell proliferation, apoptosis, cell morphometry, adhesion and wound healing process were evaluated by live/dead assay standard cell counting method, EdU labelling, Ki67, Caspase3, Zo-1 and Actin immunostaining. We demonstrated for the first time in human corneal endothelial cells ex vivo and in vitro, that ROCK inhibitor did not induce any toxicity effect and did not alter cell viability. ROCK inhibitor treatment did not induce human corneal endothelial cells proliferation. However, ROCK inhibitor significantly enhanced adhesion and wound healing. The present study shows that the selective ROCK inhibitor Y-27632 has no effect on human corneal endothelial cells proliferative capacities, but alters cellular behaviours. It induces changes in cell shape, increases cell adhesion and enhances wound healing ex vivo and in vitro. Its absence of toxicity, as demonstrated herein, is relevant for its use in human therapy.
Direct Comparison of the BD ProbeTec ET System with In-House LightCycler PCR Assays for Detection of <i>Chlamydia trachomatis</i> and <i>Neisseria gonorrhoeae</i> from Clinical Specimens (2004)

The commercial BD ProbeTec ET (BDPT) system for the detection of Neisseria gonorrhoeae and Chlamydia trachomatis from clinical specimens was compared with our in-house LightCycler real-time PCR (LC-PCR) assays. Specimens initially positive by the BDPT system were retested by our LC-PCR assays. Our results for C. trachomatis testing indicate a 91.2% agreement when the results of 114 clinical specimens, initially positive by BDPT over a wide range of method-other-than-acceleration (MOTA) scores, were retested by our LC-PCR assay. The agreement between the two systems improved to 96% when only MOTA scores of >30,000 were retested by the LC-PCR assay. The overall agreement between the two systems for Neisseria gonorrhoeae detection from 155 clinical specimens was only 77.4%, with agreement particularly low (24.1%) for MOTA scores ranging from 2,000 to 19,999. Repeat testing of specimens with the BDPT only closely correlated with that seen by others demonstrating that reproducibility of the BDPT system for specimens initially within the MOTA score range from 2,000 to 9,999 is problematic, especially for Neisseria gonorrhoeae testing. With our study, we proposed an algorithm for C. trachomatis and N. gonorrhoeae testing which involves screening with the BDPT system followed by selective use of our in-house LC-PCR assays.
The Influence of Video Quality on Perceived Audio Quality and Vice Versa (1999)

Three questions are being studied. Question one: To what extent is the perceived audio quality of an audiovisual stream influenced by the video quality? Question two is the reverse: To what extent is the perceived video quality of an audiovisual stream influenced by the audio quality? Finally: How do audio and video quality contribute to the overall perceived audiovisual quality? The quality ranges from broadcast audio and video quality to standard videophone (telephone) quality. The main conclusion is that when subjects are asked to judge the audio quality of an audiovisual stimulus, the video quality will contribute significantly to the subjectively perceived audio quality. The effect is about 1.2 points on a nine-point quality scale. The reversed effect is much smaller, about 0.2 point. Furthermore a simple mapping from the audio and video quality to the overall audiovisual quality is given, and it is shown that the video quality dominates the overall perceived audiovisual quality in nonconversational experiments.
Specific Identification of Glycoproteins Bearing the Tn Antigen in Human Cells (2017)

Glycoproteins contain a wealth of valuable information regarding the development and disease status of cells. In cancer cells, some glycans (such as the Tn antigen) are highly up-regulated, but this remains largely unknown for glycoproteins with a particular glycan. Herein, an innovative method combining enzymatic and chemical reactions was first designed to enrich glycoproteins with the Tn antigen. Using synthetic glycopeptides with O-GalNAc (the Tn antigen) or O-GlcNAc, we demonstrated that the method is selective for glycopeptides with O-GalNAc and can distinguish between these two modifications. The diagnostic ions from the tagged O-GalNAc further confirmed the effectiveness of the method and confidence in the identification of glycopeptides with the Tn antigen by mass spectrometry. Using this method, we identified 96 glycoproteins with the Tn antigen in Jurkat cells. The method can be extensively applied in biological and biomedical research.
Schedule for IP Address Space Management Guidelines (1992)

This memo suggests a schedule for the implementation of the IP network
number allocation plan described in RFC 1366. This memo provides
information for the Internet community. It does not specify an
Internet standard.
ApolloCar3D: A Large 3D Car Instance Understanding Benchmark for Autonomous Driving (2018)

Autonomous driving has attracted remarkable attention from both industry and academia. An important task is to estimate 3D properties(e.g.translation, rotation and shape) of a moving or parked vehicle on the road. This task, while critical, is still under-researched in the computer vision community - partially owing to the lack of large scale and fully-annotated 3D car database suitable for autonomous driving research. In this paper, we contribute the first large-scale database suitable for 3D car instance understanding - ApolloCar3D. The dataset contains 5,277 driving images and over 60K car instances, where each car is fitted with an industry-grade 3D CAD model with absolute model size and semantically labelled keypoints. This dataset is above 20 times larger than PASCAL3D+ and KITTI, the current state-of-the-art. To enable efficient labelling in 3D, we build a pipeline by considering 2D-3D keypoint correspondences for a single instance and 3D relationship among multiple instances. Equipped with such dataset, we build various baseline algorithms with the state-of-the-art deep convolutional neural networks. Specifically, we first segment each car with a pre-trained Mask R-CNN, and then regress towards its 3D pose and shape based on a deformable 3D car model with or without using semantic keypoints. We show that using keypoints significantly improves fitting performance. Finally, we develop a new 3D metric jointly considering 3D pose and 3D shape, allowing for comprehensive evaluation and ablation study. By comparing with human performance we suggest several future directions for further improvements.
Bordetella Adenylate Cyclase Toxin Mobilizes Its β2 Integrin Receptor into Lipid Rafts to Accomplish Translocation across Target Cell Membrane in Two Steps (2010)

Bordetella adenylate cyclase toxin (CyaA) binds the alpha(M)beta(2) integrin (CD11b/CD18, Mac-1, or CR3) of myeloid phagocytes and delivers into their cytosol an adenylate cyclase (AC) enzyme that converts ATP into the key signaling molecule cAMP. We show that penetration of the AC domain across cell membrane proceeds in two steps. It starts by membrane insertion of a toxin 'translocation intermediate', which can be 'locked' in the membrane by the 3D1 antibody blocking AC domain translocation. Insertion of the 'intermediate' permeabilizes cells for influx of extracellular calcium ions and thus activates calpain-mediated cleavage of the talin tether. Recruitment of the integrin-CyaA complex into lipid rafts follows and the cholesterol-rich lipid environment promotes translocation of the AC domain across cell membrane. AC translocation into cells was inhibited upon raft disruption by cholesterol depletion, or when CyaA mobilization into rafts was blocked by inhibition of talin processing. Furthermore, CyaA mutants unable to mobilize calcium into cells failed to relocate into lipid rafts, and failed to translocate the AC domain across cell membrane, unless rescued by Ca(2+) influx promoted in trans by ionomycin or another CyaA protein. Hence, by mobilizing calcium ions into phagocytes, the 'translocation intermediate' promotes toxin piggybacking on integrin into lipid rafts and enables AC enzyme delivery into host cytosol.
Sensitization and tolerance (2001)

The mechanisms responsible for sensitization, in particular within the gastrointestinal tract, are IgE-mediated as well as of a non-IgE-mediated, immunological origin. The phenomenon that is the opposite of sensitization is the maintenance of tolerance and is exemplified by the phenomenon 'oral tolerance'. The cytokines transforming growth factor beta and interferon gamma have been shown to be key immunoregulatory cytokines in oral tolerance. A new experimental model of eosinophilic allergic gastroenteritis has been developed with the use of encapsulated dietary antigen. The model was used in mice with genetic deletions of the eosinophil chemokine eotaxin or of the cytokine IL-5, demonstrating the importance of eotaxin. In clinical allergy research, a major question has been to explain the global increase in asthma and allergy. The 'hygiene hypothesis' states that a lack of maturation of the infant immune system from a T helper 2 to a T helper 1 type of immune response may be caused by less microbial stimulation in Western societies. Several lines of data support this hypothesis. However, apart from the genetic constitution of the individual, breastfeeding in infancy may be the most important single determinant for the development of clinical tolerance.
NEW MULTIDENTATE LIGANDS. XXV. THE COORDINATION CHEMISTRY OF DIVALENT METAL IONS WITH DIGLYCOLIC ACID, CARBOXYMETHYLTARTRONIC ACID AND DITARTRONIC ACID (1984)

Abstract Potentiometric determinations of protonation constants and metal binding constants of the ether polycarboxylate ligands diglycolic, carboxymethyltartronic, and ditartronic acid are reported. The magnitudes of the equilibrium constants are discussed in terms of the functional groups present. Competition between ditartronic acid and nitrilotriacetic acid (NTA) for calcium(II) demonstrates that the ether polycarboxylates are particularly effective as sequestering agents in weakly to moderately acid solutions.
Stop clickbait: detecting and preventing clickbaits in online news media (2016)

Most of the online news media outlets rely heavily on the revenues generated from the clicks made by their readers, and due to the presence of numerous such outlets, they need to compete with each other for reader attention. To attract the readers to click on an article and subsequently visit the media site, the outlets often come up with catchy headlines accompanying the article links, which lure the readers to click on the link. Such headlines are known as Clickbaits. While these baits may trick the readers into clicking, in the long-run, clickbaits usually don't live up to the expectation of the readers, and leave them disappointed. In this work, we attempt to automatically detect clickbaits and then build a browser extension which warns the readers of different media sites about the possibility of being baited by such headlines. The extension also offers each reader an option to block clickbaits she doesn't want to see. Then, using such reader choices, the extension automatically blocks similar clickbaits during her future visits. We run extensive offline and online experiments across multiple media sites and find that the proposed clickbait detection and the personalized blocking approaches perform very well achieving 93% accuracy in detecting and 89% accuracy in blocking clickbaits.
Neutrophil function is preserved in a pooled granulocyte component prepared from whole blood donations (2008)

Whole blood-derived granulocytes (buffy coats) are issued as an alternative to apheresis donations, but are heavily contaminated with red cells and platelets and there is minimal in vitro data describing their functionality. We developed a purer pooled granulocyte component (PGC) from whole blood donations by pooling 10 ABO-matched buffy coats with 400 ml of platelet additive solution (SSP+) and re-centrifuging. The PGC was irradiated (25-50 Gy) and neutrophil viability, chemotaxis, phagocytosis and respiratory burst activity were determined by flow cytometry. Results from 13 PGC at 16-20 h following donation were compared with those obtained from 20 standard individual buffy coats and with fresh whole blood. The PGC contained similar numbers of neutrophils (approximately 0.9 x 10(10)) with a reduced volume and haemoglobin content when compared with 10 individual buffy coats. Neutrophils in the PGC maintained >90% viability, oxidative burst and phagocytic activity and their ability to migrate towards a chemoattractant 16-20 h following donation, which is similar to results obtained with either fresh whole blood or standard buffy coats. Therefore, neutrophil function in the PGC was preserved 16-20 h following donation, but this product had significantly lower red cell contamination compared with 10 buffy coats, which are currently transfused.
ANTIVIRAL ACTION AND SELECTIVITY OF 6‐AZAURIDINE (1977)

6-Azauridine (AzUrd) is a broad-spectrum antimetabolite that inhibits both DNA and RNA virus multiplication. Prior work indicated that several AzUrd-sensitive viruses induced an increase in the level of uridine kinase, and this might explain the selective activity of AzUrd on such viruses. Present studies compared AzUrd sensitive and resistant viruses with respect to their orotic acid pathways by labeling cells with [14C]-orotic acid during the latent period of viral infection. No differences were detected by this method with either vaccinia, Newcastle disease, or vesicular stomatitis viruses. AzUrd inhibits transport of orotic acid into the cell by 30%, while incorporation of orotic acid into cellular RNA is inhibited by 50% (taking into consideration the 30% already noted) when the highest concentration of antimetabolite is used. This suggests that, in addition to blocking orotidylic acid decarboxylase, AzUrd may act on some other site (sites) of action in the inhibition of virus multiplication.
65nm SOI CMOS SoC Technology for Low-Power mmWave and RF Platform (2008)

An RF and mm-wave platform developed in 65 nm SOI CMOS technology is presented. The SOI FET performance in a wired cell is measured up to f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</sub> =300 GHz and 200 GHz for NFET and PFET. Ring oscillator records 3.6 psec minimum inverter stage delay. Back-end-of-line vertical native capacitor (VNCAP) and on-chip inductor performances are reported. The performance scaling trends of mmWave PLL front-end components are presented.
Capacity Analysis Considering Channel Resource Overhead for Mobile Internet Access(WiBro) (2005)

Wireless mobile Internet access is becoming an important segment for the wireless industry. In this paper the new system, WiBro, being standardized in Korea is introduced. We address some of the physical layer aspects and the corresponding impacts on system performance. To provide the solution for optimized network operation, we evaluate the capacity of WiBro in various network conditions with the developed system level simulator. Simulation results provide insight on how performance varies within the coverage area according to the values of system parameters. Also, we derive the adequate values to maximize capacity considering channel resource overhead.
Modeling and analysis of a multi-output cuk converter (1980)

A small signal network model for an experimental high frequency triple-output Ćuk do-to-dc converter system is developed in analytical detail including provisions for its unique ramp slope control regulatory circuitry, magnetic coupling between selected port inductances, and scaling transformer inductive effects. Results of empirical and computer simulations of a representative 200 KHz, 55W design are discussed along with recommendations for dynamic operational improvements.
A new division algorithm based on lookahead of partial-remainder (LAPR) for high-speed/low-power coding applications (1999)

A new polynomial division algorithm in finite field GF(2/sup m/) based on the lookahead of partial-remainder (LAPR) is proposed. Since our algorithm is based on partial division on group basis and lookahead technique exploiting the linearity in finite field arithmetic, it is possible to completely eliminate polynomial multiplications leading to highly increased throughput per unit time. The inherent regularity and feedforward nature of our algorithm make it possible to be fully pipelined. When pipelined, its throughput is one quotient and one remainder per clock cycle, regardless of the degree of dividend polynomial, which is orders of magnitude faster than the conventional architecture using linear feedback shift register. An area-efficient sequential architecture based on LAPR is also presented, Although the throughput rate of sequential architecture is lower than that of the pipelined one, it is still higher than that of any division architecture ever reported. They are shown to be efficient, regular, and easily expandable, and hence, naturally suitable for very large scale integration implementation. In systems requiring modest speed, the high-speed nature of our proposed architecture can be traded for low power consumption by reducing clock rate. We verified the general validity of the division algorithm based on LAPR by mathematical manipulation and simulation. The superiority of our proposed architecture compared with other reported ones is demonstrated with regard to its throughput, latency delays, and power.