gebhart/patrepeval huggingface dataset:
Linear Programmed Thermal Degradation Mass Spectrometry (1978)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTLinear Programmed Thermal Degradation Mass SpectrometryT. H. Risby and A. L. YergeyCite this: Anal. Chem. 1978, 50, 3, 326A–334APublication Date (Print):March 1, 1978Publication History Published online31 May 2012Published inissue 1 March 1978https://pubs.acs.org/doi/10.1021/ac50025a719https://doi.org/10.1021/ac50025a719research-articleACS PublicationsRequest reuse permissionsArticle Views247Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Synthesis of (.+-.)-2,3-cis-stegobinone, (.+-.)-cis-2,3-dihydro-2,3,5-trimethyl-6-(1-methyl-2-oxobutyl)-4H-pyran-4-one, The sex pheromone of drugstore beetle. (1983)

Stegobinone 4, the sex pheromone of the drugstore beetle (Stegobium paniceum L.), has recently been isolated and its gross structure established as 2,3-xiihydro-2,3,5-trimethyl-6-( 1 -methyl-2-oxobutyl)-4//-pyran-4-one by spectroscopic evidence1?2) and biomimetic syn-
New High-Affinity Monoclonal Antibodies against Shiga Toxin 1 Facilitate the Detection of Hybrid Stx1/Stx2 In Vivo (2014)

These new mAbs provide a mix of availability, utility, versatility, and most importantly, increased sensitivity for detection of Stx1. There are numerous potential applications for these mAbs, including low-cost detection assays and therapeutic use. Analysis of hybrid Stx1/2 could provide new insights on the structure, activity, and cellular targets of Shiga toxins.
Optical Tracker For Longwall Coal Shearer (1989)

Photographic record yields information for correction of vehicle path. Tracking system records lateral movements of longwall coal-shearing vehicle. System detects lateral and vertical deviations of path of vehicle moving along coal face, shearing coal as it goes. Rides on rails in mine tunnel, advancing on toothed track in one of rails. As vehicle moves, retroreflective mirror rides up and down on teeth, providing series of pulsed reflections to film recorder. Recorded positions of pulses, having horizontal and vertical orientations, indicate vertical and horizontal deviations, respectively, of vehicle.
Poly(phenylene) and <i>m</i>‐Terphenyl as Powerful Protecting Groups for the Preparation of Stable Organic Hydroxides (2016)

Four benzimidazolium hydroxide compounds, in which the C2-position is attached to a phenyl group possessing hydrogen, bromine, methyl groups, or phenyl groups at the ortho positions, are prepared and investigated for stability in a quantitative alkaline stability test. The differences between the stability of the various protecting groups in caustic solutions are rationalized on the basis of their crystal structures and DFT calculations. The highest stability was observed for the m-terphenyl-protected benzimidazolium, showing a half-life in 3 M NaOD/CD3OD/D2O at 80 °C of 3240 h. A high-molecular-weight polymer analogue of this model compound is prepared that exhibits excellent mechanical properties, high ionic conductivity and ion-exchange capacity, as well as remarkable hydroxide stability in alkaline solutions: only 5% degradation after 168 h in 2 M KOH at 80 °C. This is the most stable hydroxide-conducting benzimidazolium polymer to date.
Annonaceous acetogenins: An updated review (1993)

Abstract The Annonaceous acetogenins are an exciting new class of bioactive natural products whose antitumour, pesticidal and other bioactivities are due to inhibition of electron transport in mitochondria. This paper tabulates the 61 compounds in this class which have been published in the period of 1990–1992 and reviews recent progress with the chemistry and biology of these potent compounds. (Appendices will be published in the next issue.)
Interval Observer for SOC Estimation in Parallel-Connected Lithium-ion Batteries (2020)

The internal states of Lithium-ion batteries, notably state of charge (SOC), need to be carefully monitored during battery operation to manage energy and safety. In this paper, we propose an interval observer for SOC estimation in an electrically and thermally coupled parallel connection of cells. This is a particularly challenging problem because mathematically cells in parallel yield a system of differential-algebraic equations (DAE), which are more difficult to handle than ordinary differential equations (e.g. a series string of cells). For a large battery pack with thousands of cells, applying an estimation algorithm on each and every cell would be mathematically and computationally intractable. These issues are tackled using an interval observer based on a coupled equivalent circuit-thermal model. The key novelty lies in considering cell heterogeneity as well as state-dependent parameters as unknown, but with bounded uncertainty. The resulting interval observer maps bounded uncertainties to a feasible set of state estimation, and is independent of the number of cells in parallel. Stability and inclusion of the interval observer are proven and validated through numerical studies.
MOCZ for Blind Short-Packet Communication: Practical Aspects (2020)

We investigate practical aspects of a recently introduced blind (noncoherent) communication scheme, called modulation on conjugate-reciprocal zeros (MOCZ). MOCZ is suitable for a reliable transmission of sporadic and short-packets at ultra-low latency and high spectral efficiency via unknown multipath channels, which are assumed to be static over the receive duration of one packet. The information is modulated on the zeros of the transmitted discrete-time baseband signal's z- transform. Because of ubiquitous impairments between the transmitter and receiver clocks, a carrier frequency offset occurs after down-conversion to the baseband. This results in a common rotation of the zeros. To identify fractional rotations of the base angle in the zero-pattern, we propose an oversampled direct zero-testing decoder to identify the most likely one. Integer rotations correspond to cyclic shifts of the binary message, which we determine by cyclically permutable codes (CPC). Additionally, the embedding of CPCs into cyclic codes, enables additive error-correction which reduces the bit-error-rate tremendously. Furthermore, we exploit the trident structure in the signal's autocorrelation for an energy based detector to estimate timing offsets and the effective channel delay spread. We finally demonstrate how this joint data and channel estimation can be largely improved by receive antenna diversity at low SNR.
Four-Antigen Mixture Containing V-Cyclin for Serological Screening of Human Herpesvirus 8 Infection (2009)

Improved diagnostic reagents and testing are currently needed for the serological detection of human herpesvirus 8 (HHV-8) infections. We evaluated the luciferase immunoprecipitation systems (LIPS) for profiling antibody responses to a panel of HHV-8 proteins for diagnosis of Kaposi sarcoma (KS)-infected individuals. Using a pilot serum set, LIPS detected robust antibody responses to several known antigens, and a screen of 14 additional HHV-8 proteins identified v-cyclin as a potentially new diagnostic antigen. In evaluating a training-serum set, a four-antigen panel (K8.1, v-cyclin, ORF65, and a LANA fragment) was found to provide sufficient information for diagnosis. Analysis of a validation serum set using the combined results from these four separate antigen tests showed 100% sensitivity and 100% specificity. Furthermore, a LIPS format using a mixture of the four antigens, which simplifies data collection and analysis, closely matched the diagnostic performance of the combined separate tests (R = 0.95). This four-antigen mixture format analyzed with the validation serum set also showed 100% sensitivity and 100% specificity but was not statistically different from two separate enzyme-linked immunosorbent assays (94% sensitivity and 100% specificity) using baculovirus-produced LANA and bacterially produced K8.1. Heat map analysis of KS patient antibody titers revealed marked heterogeneity in humoral responses to this four-antigen panel. Overall, the LIPS assay showed 97% sensitivity, and positive anti-v-cyclin antibodies were detected in approximately 75% of the KS sera. These results suggest that LIPS screening using an antigen mixture is a sensitive and high-throughput method for serological screening of HHV-8 infection in individuals with KS.
On the Performance of Hybrid Foil-Magnetic Bearings (1998)

Recent technological advancements make hybridization of the magnetic and foil bearings both possible and extremely attractive. Operation of the foil/magnetic bearing takes advantage of the strengths of each individual bearing while minimizing each others weaknesses. In this paper one possible hybrid foil and magnetic bearing arrangement is investigated and sample design and operating parameters are presented. One of the weaknesses of the foil bearings, like any hydrodynamic bearing, is that contact between the foil bearing and the shaft occurs at rest or at very low speeds and it has low load carrying capacity at low speeds. For high speed applications, AMBs are, however, vulnerable to rotor-bending or structural resonances that can easily saturate power amplifiers and make the control system unstable. Since the foil bearing is advantageous for high speed operation with a higher load carrying capacity, and the magnetic bearing is so in low speed range, it is a natural evolution to combine them into a hybrid bearing system thus utilizing the advantages of both. To take full advantage of the foil and magnetic elements comprising a hybrid bearing, it is imperative that the static and dynamic characteristics of each bearing be understood. This paper describes the development of a new analysis technique that was used to evaluate the performance of a class of gas-lubricated journal bearings. Unlike conventional approaches, the solution of the governing hydrodynamic equations dealing with compressible fluid is coupled with the structural resiliency of the bearing surfaces. The distribution of the fluid film thickness and pressures, as well as the shear stresses in a finite-width journal bearing, are computed. Using the Finite Element (FE) method, the membrane effect of an elastic top foil was evaluated and included in the overall analytical procedure. Influence coefficients were generated to address the elasticity effects of combined top foil and elastic foundation on the hydrodynamics of journal bearings, and were used to expedite the numerical solution. The overall program logic proved to be an efficient technique to deal with the complex structural compliance of various foil bearings. Parametric analysis was conducted to establish tabulated data for use in a hybrid foil/magnetic bearing design analysis. A load sharing control algorithm between the foil and magnetic elements is also discussed.
Optimized Fused Floating-Point Many-Term Dot-Product Hardware for Machine Learning Accelerators (2019)

This paper describes optimizations for the critical maximum exponent and alignment operations, with scalability for many-term fused floating-point dot-product units. The impact of these optimizations is quantified for up to 32-term BFloat16 weight/activation inputs with single-precision dot-product output, targeted for machine learning accelerators. Area and energy efficiency results are compared across performance targets, design parameters, and data statistics.
Dimeric Macrocyclic Antagonists of Inhibitor of Apoptosis Proteins for the Treatment of Cancer (2015)

A series of dimeric macrocyclic compounds were prepared and evaluated as antagonists for inhibitor of apoptosis proteins. The most potent analogue 11, which binds to XIAP and c-IAP proteins with high affinity and induces caspase-3 activation and ultimately cell apoptosis, inhibits growth of human melanoma and colorectal cell lines at low nanomolar concentrations. Furthermore, compound 11 demonstrated significant antitumor activity in the A875 human melanoma xenograft model at doses as low as 2 mg/kg on a q3d schedule.
Increased accuracy of planning tools for optimization of dynamic multileaf collimator delivery of radiotherapy through reformulated objective functions (2018)

The purpose of this study is to examine in a clinical setting a novel formulation of objective functions for intensity-modulated radiotherapy treatment plan multicriteria optimization (MCO) that we suggested in a recent study. The proposed objective functions are extended with dynamic multileaf collimator (DMLC) delivery constraints from the literature, and a tailored interior point method is described to efficiently solve the resulting optimization formulation. In a numerical planning study involving three patient cases, DMLC plans Pareto optimal to the MCO formulation with the proposed objective functions are generated. Evaluated based on pre-defined plan quality indices, these DMLC plans are compared to conventionally generated DMLC plans. Comparable or superior plan quality is observed. Supported by these results, the proposed objective functions are argued to have a potential to streamline the planning process, since they are designed to overcome the methodological shortcomings associated with the conventional penalty-based objective functions assumed to cause the current need for time-consuming trial-and-error parameter tuning. In particular, the increased accuracy of the planning tools imposed by the proposed objective functions has the potential to make the planning process less complicated. These conclusions position the proposed formulation as an alternative to existing methods for automated planning.
<title>Tube leak detection and isolation in industrial boiler systems</title> (1999)

This paper deals with tube leak detection in industrial boilers. A decentralized information processing approach is used to detect and isolate the location of boilers tube leaks. Tube leak sensitive variables (TLSV) are used as the information source for detection and isolation. Such variables are already collected by the system for the purpose of control and monitoring. Given the TLSV, artificial neural networks are used to detect the presence of a leak and its location in the boiler. The proposed approach was successfully applied to tube leak detection and isolation in five subsystems of a utility boiler.
Vesicle capture on patterned surfaces coated with amphiphilic biopolymers (2010)

We describe a simple way to create patterns of “soft” biomolecular nanostructures such as vesicles on “hard” surfaces such as gold. The key to our approach is the use of an amphiphilic biopolymer as an “interconnect” or tether. The polymer is hydrophobically modified chitosan (hm-chitosan), which is obtained by covalently attaching alkyl tails to the backbone of chitosan. We electrodeposit films of hm-chitosan onto microscale gold cathodes formed by lithography on a silicon wafer. Subsequently, the hm-chitosan films are used to spontaneously capture vesicles from solution; this is demonstrated both for surfactant as well as lipid vesicles (liposomes). Vesicles remain strongly bound to the hm-chitosan to a much greater extent than to native chitosan. This suggests that the mechanism for vesicle capture involves non-covalent binding of hydrophobes from hm-chitosan chains to the hydrophobic portions of vesicle bilayers. Importantly, the vesicles captured by hm-chitosan films are intact—this is shown both by direct visualization of captured vesicles (via optical and cryo-transmission electron microscopy) as well as through the capture and subsequent disruption of dye-filled vesicles. Various microscale patterns of immobilized vesicles are created and the vesicles are demonstrated to be capable of sensing a reporter molecule from the external solution.
Preparation of Fine, Spherical Yttria‐Stabilized Zirconia by the Spray‐Pyrolysis Method (1989)

Fine yttria‐stabilized zirconia powders were prepared by the spray pyrolysis of aqueous solutions of ZrOCl 2 ·8H 2 O and Y(NO 3 ) 3 ·5H 2 O (3 mol%). An appropriate thermal treatment resulted in slightly porous spherical particles with a narrow size distribution. The sintering ability of these powders was evaluated.
Soldering to a single atomic layer (2007)

The standard technique to make electrical contact to nanostructures is electron beam lithography. This method has several drawbacks including complexity, cost, and sample contamination. We present a simple technique to cleanly solder submicron sized, Ohmic contacts to nanostructures. To demonstrate, we contact graphene, a single atomic layer of carbon, and investigate low- and high-bias electronic transport. We set lower bounds on the current carrying capacity of graphene. A simple model allows us to obtain device characteristics such as mobility, minimum conductance, and contact resistance.
Coded Bidirectional Relaying (2005)

In this summary, we consider bi-directional communication between a transmitter and receiver communicating via a relay station. We present a novel communication method based on joint data packet encoding in conjunction with exploitation of a priori known information that enables reduced number of transmissions, whereby enhancing aggregate throughput.
Demonstration of a 12 x 155 Mb/s WDM PON under outside plant temperature conditions (1997)

A 12-channel wavelength division multiplexed (WDM) passive optical network (PON) at 155 Mb/s with 63 km of standard single-mode fiber (SMF) was demonstrated under simulated outside plant temperature conditions. A multifrequency laser (MFL) was used as the transmitter and a waveguide grating router (WGR) as the demultiplexer. A 20/spl deg/C/h temperature change of the WGR could be tracked by changing the MFL temperature and resulted in a power penalty in the detected bit-error rate (BER) of less than 0.75 dB. A scheme to increase the tracking sensitivity by multiple WGR passes is demonstrated.
No regression algorithm for the enumeration of projections in SQL queries with joins and outer joins (1995)

The execution time of an SQL query can be reduced significantly by considering different schedules for the operations specified in the query. The benefits of considering different schedules, a hallmark of strength in query optimization, are not usually exploited if a query contains projections along with binary operations. This paper presents a set of no regression algorithms that are capable of generating different schedules for the queries containing projections and binary operations.
A DNAzyme‐Based Colorimetric Paper Sensor for <i>Helicobacter pylori</i> (2019)

The reliable detection of pathogenic bacteria in complex biological samples using simple assays or devices remains a major challenge. Herein, we report a simple colorimetric paper device capable of providing specific and sensitive detection of Helicobacter pylori (H. pylori), a pathogen strongly linked to gastric carcinoma, gastric ulcers, and duodenal ulcers, in stool samples. The sensor molecule, an RNA-cleaving DNAzyme obtained through in vitro selection, is activated by a protein biomarker from H. pylori. The colorimetric paper sensor, designed on the basis of the RNA-cleaving property of the DNAzyme, is capable of sensitive detection of H. pylori in human stool samples with minimal sample processing and provides results in minutes. It remains fully functional under storage at ambient temperature for at least 130 days. This work lays a foundation for developing DNAzyme-enabled paper-based point-of-care diagnostic devices for monitoring pathogens in complex samples.
Airway Gene Expression in Chronic Obstructive Pulmonary Disease (2009)

Although cigarette smoking is the major cause of chronic obstructive pulmonary disease (COPD), only a subset of smokers develops this disease. There is significant clinical, radiographic, and pathologic heterogeneity within smokers who develop COPD that likely reflects multiple molecular mechanisms of disease. It is possible that variations in the individual response to cigarette smoking form the basis for the distinct clinical and molecular phenotypes and variable natural history associated with COPD. Using the biologic premise of a molecular field of airway injury created by cigarette smoking, this response to tobacco exposure can be measured by molecular profiling of the airway epithelium. Noninvasive study of this field effect by profiling airway gene expression in patients with COPD holds important implications for our understanding of disease heterogeneity, early disease detection, and identification of novel disease-modifying therapies.
Computer modeling as a tool to predict deposition rate and film composition in the reactive sputtering process (1998)

Reactive sputtering is a widely used technique to deposit oxides, nitrides, etc. A serious drawback of this technique, however, is the drastic decrease in deposition rate that almost always occurs when depositing compound films as compared to depositing pure metal film. In many cases it is possible to overcome this problem by operating the process in the narrow critical processing region between metallic and compound mode sputtering. In this processing region, however, the composition of the deposited compound thin film is extremely sensitive to the processing conditions. It is, therefore, very interesting to investigate the sensitivity of different processing parameters on the overall processing behavior. Computer modeling can be used as a tool to increase the understanding of this complex process. We will show that such results can be used to illustrate the individual effects of the major involved processing parameters. It also serves to assist in the work of process optimization. The relationship between target poisoning, argon current density, deposition rate, reactive gas supply, partial pressure, total pressure, and film composition have been carefully examined. In particular, we will point out a serious limitation that may arise during high rate multielement reactive sputter deposition. The effect of different reactivity of the involved elements may cause that one of the elements during deposition will not be fully oxidized.
WiDeo: fine-grained device-free motion tracing using RF backscatter (2015)

Could we build a motion tracing camera using wireless communication signals as the light source? This paper shows we can, we present the design and implementation of WiDeo, a novel system that enables accurate, high resolution, device free human motion tracing in indoor environments using WiFi signals and compact WiFi radios. The insight behind WiDeo is to mine the backscatter reflections from the environment that WiFi transmissions naturally produce to trace where reflecting objects are located and how they are moving. We invent novel backscatter measurement techniques that work in spite of the low bandwidth and dynamic range of WiFi radios, new algorithms that separate out the moving backscatter from the clutter that static reflectors produce and then trace the original motion that produced the backscatter in spite of the fact that it could have undergone multiple reflections. We prototype WiDeo using off-the-shelf software radios and show that it accurately traces motion even when there are multiple independent human motions occurring concurrently (up to 5) with a median error in the traced path of less than 7cm.