gebhart/patrepeval huggingface dataset:
Designing Time-Hopping Ultrawide Bandwidth Receivers for Multiuser Interference Environments Modeling of interference effects indicates that several newly-proposed receiver designs may provide better performance than conventional linear receivers when interference is significant. (2009)

The multiple-user interference (MUI) in time- hopped impulse-radio ultrawide bandwidth (UWB) systems is impulse-like and poorly approximated by a Gaussian distribu- tion. Therefore, conventional matched filter receiver designs, which are optimal for Gaussian noise, are not fully efficient for UWB applications. Several alternative distributions for approx- imating the MUI process and the MUI-plus-noise process in UWB systems are motivated and compared. These distributions have in common that they are more impulsive than the Gaussian approximation, with a greater area in the tails of the probability density function (pdf) compared to a Gaussian pdf. The improved MUI and MUI-plus-noise models are utilized to derive new receiver designs for UWB applications, which are shown to be superior to the conventional matched filter receiver. Multipath propagation is abundant in UWB channels and is exploited by a Rake receiver. A Rake receiver uses multiple fingers to comb the multipath rays with a conventional matched filter implemented in each finger. Rake structures utilizing the new receiver designs that are suitable for reception of UWB signals in multipath fading channels are provided. An optimal performance benchmark, based on an accurate theoretical model for the interference that fully explains the features of the MUI pdf, is also presented. Analysis and simulation results are shown for the novel receivers, which demonstrate that the new designs have superior performance compared to the conventional linear receiver when MUI is significant. Several adaptive receivers are shown to always match or exceed the performance of the conventional linear receiver in all MUI-plus-noise environments. Parameter estimation for the new receivers also is discussed.
Intrusion detection algorithm based on OCSVM in industrial control system (2015)

In order to detect abnormal communication behaviors efficiently in today's industrial control system, a new intrusion detection algorithm based on One-Class Support Vector Machine OCSVM is proposed in this paper. In this algorithm, a normal communication behavior model is established by using OCSVM, and the Particle Swarm Optimization algorithm is designed to optimize OCSVM model parameters. Furthermore, we adopt the normal Modbus function code sequence to train OCSVM model, and then use this model to detect abnormal Modbus TCP traffic. Our simulation results show that the proposed algorithm not only is efficient and reliable but also meets the real-time requirements of anomaly detection in industrial control system. Copyright © 2015 John Wiley & Sons, Ltd.
Durability of Flexible Molded Polyurethane Foams (1998)

In recent years, we have developed highly resilient (HR) flexible molded foams with superb durability, resilience and vibration characteristics, and we have reported that these improvements were based on control of cross link degree of polymer, morphology and mobility of hard and soft segments. This paper describes factors that dominantly influence the durability and the mechanism of fatigue by investigation of cross linking by covalent and hydrogen-bonds and the morphology of hard/soft segments. In this study, we use molded foams with different durabilities. These are TDI-based high performance/conventional HR, MDI-based high-performance/conventional HR, and hot molded foams. On the whole, a small apparent viscosity coefficient, which is calculated from vibration characteristics of the foam, and a higher cross link degree of foam polymer make static and dynamic durability of flexible molded foam better. Mobility of the soft segment, estimated by solid state NMR, also dominates dynamic durability. Accordingly, hydrogen-bonds of the hard segment contribute against creep as a cross link point in static/dynamic durability test, and tight hydrogen-bonds of hot molded foam are durable against rupture or rebonding by water molecules in the wet compression set oven. The drop in cross link degree of foam polymer was not observed during vibration durability test. Accordingly, the mechanism of fatigue could be the change of state in hydrogen-bonds or tangling of polymer-chains, or relatively macro rupture.
Hasti: Haptic and Audio Synthesis for Texture Interactions (2021)

Multi-sensory stimuli can greatly enhance immersion in interactive virtual environments. Advances in graphics algorithms and technologies like VR displays have pushed the appearance of interactive virtual worlds to unprecedented fidelity, but rendering sound and, especially, touch feedback of comparable quality remains a challenge. We describe a method for real-time synthesis of vibrotactile haptic and audio stimuli for interactions with textured surfaces in 3-D virtual environments. Standard descriptions of object geometry and material properties, including displacement and roughness texture maps typically used for physically-based visual rendering, are employed to generate realistic sound and touch feedback consistent with appearance. Our method reconstructs meso-and microscopic surface features on the fly along a contact trajectory, and runs a micro-contact dynamics simulation whose outputs drive vibrotactile haptic actuators and modal sound synthesis. An exploratory, absolute identification user study was conducted as an initial evaluation of our synthesis methods.
Synthesis of Coinage-Metal Nanoparticles from Mesityl Precursors (2003)

An anhydrous route for the synthesis of amine-capped coinage-metal nanoparticles (NP) has been developed using coinage-metal mesityl (mesityl = 2,4,6-Me3C6H2) derivatives. Under an argon atmosphere, crystalline [Cu(μ-mesityl)]5, [Ag(μ-mesityl)]4, and [Au(μ-mesityl)]5 were readily dissolved in octylamine (0.3 M solution) and subsequently injected into a heated hexadecylamine solution (300 °C), generating the corresponding metal nanoparticles. After washing with methanol and extracting with toluene, oxide-free coinage NPs were isolated and characterized by UV−vis spectroscopy and transmission electron microscopy. Under these conditions, the spherical NPs were found to be 8−9 nm in size for Cu° (no surface oxide present), 9 nm for Ag°, and 8−80 nm for Au°. Reducing the concentration of the precursor solution, the temperature of the solution, and the time of reaction led to the synthesis of Au° NPs that were 12 ± 1 nm in size.
A Naturalist Approach To Music File Name Analysis. (2001)

[TODO] Add abstract here.
Mobile Monolith Polymer Elements For Flow Control In Microfluidic Systems (2006)

A cast-in-place and lithographically shaped mobile, monolithic polymer element for fluid flow control in microfluidic devices and method of manufacture. Microfluid flow control devices, or microvalves that provide for control of fluid or ionic current flow can be made incorporating a cast-in-place, mobile monolithic polymer element, disposed within a microchannel, and driven by fluid pressure (either liquid or gas) against a retaining or sealing surface. The polymer elements are made by the application of lithographic methods to monomer mixtures formulated in such a way that the polymer will not bond to microchannel walls. The polymer elements can seal against pressures greater than 5000 psi, and have a response time on the order of milliseconds. By the use of energetic radiation it is possible to depolymerize selected regions of the polymer element to form shapes that cannot be produced by conventional lithographic patterning and would be impossible to machine.
Inhibition of Tumor Growth and Angiogenesis by SP-2, an Anti–Lectin, Galactoside-Binding Soluble 3 Binding Protein (LGALS3BP) Antibody (2014)

Accumulating evidence indicates that serum and tissue levels of lectin, galactoside-binding soluble 3 binding protein (LGALS3BP), a secreted glycoprotein, are elevated in human cancers. Recently, we have identified LGALS3BP as a factor capable of stimulating angiogenesis of microvascular endothelial cells in vitro as well as in vivo. However, the potential therapeutic implications of LGALS3BP function blockade have not been explored yet. Here, we tested the ability of an anti-LGALS3BP mouse monoclonal antibody, SP-2, to antagonize LGALS3BP-induced angiogenesis and tumor growth. The antibody was found to inhibit endothelial cell tubulogenesis induced by either conditioned medium of breast cancer and melanoma cells or human recombinant LGALS3BP. In addition, SP-2 inhibited phosphorylation of FAK and its recruitment to membrane sites as well as AKT and ERK phosphorylation promoted by LGALS3BP. When used in vivo, the antibody restrained LGALS3BP-stimulated angiogenesis and growth of tumor xenografts. Furthermore, the combination of SP-2 and low-dose bevacizumab was more effective than either agent alone. Taken together, these results lead to consideration of SP-2 as a promising candidate for LGALS3BP-targeted therapy.
Mannan-binding lectin (MBL) production from human plasma (2003)

Individuals with low levels of mannan-binding lectin (MBL) appear to be susceptible to infectious diseases. This suggests that substitution therapy with MBL might be a beneficial treatment of patients with MBL deficiency. A production process for an MBL product has been developed from a fraction II+III precipitate obtained by ethanol fractionation of plasma. The MBL process includes three chromatographic steps, where the first and key step is affinity chromatography on a cross-linked agarose matrix selecting for oligomeric, carbohydrate-binding MBL. The yield from the production process is about 25% of the plasma MBL content, and the purity is about 65%. The MBL product shows mannan-binding activity and complement-activating ability. A safety study has shown this plasma-derived MBL to be safe and well tolerated in adult MBL-deficient volunteers.
Dead-zone digital controllers for improved dynamic response of low harmonic rectifiers (2006)

This paper introduces a simple digital control method that enables fast regulation of the output voltage in low harmonic rectifiers with power factor correction (PFC). The method is based on the use of an insensitive region, i.e., "dead-zone," in analog-to-digital conversion, for elimination of the output capacitor voltage ripple in the feedback loop. The dead-zone can either be fixed and larger than the maximum ripple magnitude, or it can be dynamically adjusted in accordance with the output load. Simple implementations of these two dead-zone controllers are shown on an experimental completely digitally controlled 250-W boost PFC operating at 200-kHz switching frequency. The experimental results show that this control method results in low current harmonics and improved load transient responses, which are significantly faster than in low-harmonic rectifiers with conventional low-bandwidth voltage-loop controllers.
Pervasive Diagnosis (2010)

In model-based production, a planner uses a system description to create plans that achieve production goals. The same description can be used by model-based diagnosis to infer the condition of components from sensor data. When production is realized by a sequence of plans, prior work has demonstrated that diagnosis can be used to adapt the plans to compensate for component degradation. However, the sources of diagnostic information are severely limited. Diagnosis must either make inferences from observations during production over which it has no control (passive diagnosis), or production must be halted to introduce diagnostic-specific plans (explicit diagnosis). We observe that the declarative nature of the model-based approach allows the planner to achieve production goals in multiple ways. This flexibility is exploited by a novel paradigm, i.e., <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">pervasive (active) diagnosis</i> , which constructs <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">informative production plans</i> that simultaneously achieve production goals while uncovering additional diagnostic information about the condition of components. We present an efficient heuristic search for these informative production plans and show through experiments on a model of an industrial digital printing press that the theoretical increase in long-run productivity can be realized on practical real-time systems. We obtain higher long-run productivity than a decoupled combination of planning and diagnosis.
Properties of our developing next-generation photomask substrate (1999)

We have developed a synthetic silica glass substrate for the next generation, which the resolves three demands of the photo-lithography for substrates: (1) material quality, (2) surface quality, (3) dimensional quality. (1) Synthetic silica substrate is required to be ArF-resistant, corresponding to 0.1 micrometer-order-rule-lithography. We have found a way of controlling the impurities in the synthesis of silica and developed a high-transmission substrate for 193 nm-excimer laser as well as for the 248 nm model. Also when the repeat fluence of the beam has a stronger intensity than in the case of lithography, it dose not affect the transmission property and the other optical properties. (2) The surface of the substrates must have no basic defects and must be extremely smooth because of the need for precise lithography. We are working on a method of developing a surface that has no defects larger than 0.3 micrometer in size. It is also remarkably resistant to such etchants as hydrogen fluoride and alkali solutions. (3) Global flatness of substrates is highly important in dimensional quality. We have already made substrates with 0.5 micrometer-flatness 6 inch and have prospects of developing substrates with submicron-flatness of 230 mm.
Quality of Service Issues in Micro Mobility Enabled Wireless Access Networks (2010)

Provision of Quality of Service (QoS) and Micro Mobility management is imperative to delivering content seamlessly and efficiently to the next generation of IP based mobile networks. Micro mobility management ensures that during handover the disruption caused to the live sessions are kept to a minimum. On the other hand, QoS mechanisms ensure that during a session the required level of service is maintained. Though many micro mobility and QoS mechanisms have been proposed to solve their respective aspects of network operation, they often have interaction with each other and can lead towards network performance degradation. This chapter focuses specifically on the issues of interaction between micro mobility and QoS mechanisms. Special focus is given to the relatively unexplored area of the impact Mobility Agents can have on the wireless access network. Mobility Agents play a central role in providing micro mobility support. However, their presence (location and number) can affect the routing as well as the handover delay. Through an example network this issue is highlighted. Following which an optimization framework is proposed to deploy Mobility Agents optimally within a micro mobility enabled wireless access network to minimise both the routing overhead as well as the handover delay. Results show considerable improvements in comparison to deploying the Mobility Agents arbitrarily.
Efficient Perovskite Hybrid Photovoltaics via Alcohol‐Vapor Annealing Treatment (2015)

In this work, alcohol‐vapor solvent annealing treatment on CH 3 NH 3 PbI 3 thin films is reported, aiming to improve the crystal growth and increase the grain size of the CH 3 NH 3 PbI 3 crystal, thus boosting the performance of perovskite photovoltaics. By selectively controlling the CH 3 NH 3 I precursor, larger‐grain size, higher crystallinity, and pinhole‐free CH 3 NH 3 PbI 3 thin films are realized, which result in enhanced charge carrier diffusion length, decreased charge carrier recombination, and suppressed dark currents. As a result, over 43% enhanced efficiency along with high reproducibility and eliminated photocurrent hysteresis behavior are observed from perovskite hybrid solar cells (pero‐HSCs) where the CH 3 NH 3 PbI 3 thin films are treated by methanol vapor as compared with that of pristine pero‐HSCs where the CH 3 NH 3 PbI 3 thin films are without any alcohol vapor treatment. In addition, the dramatically restrained dark currents and raised photocurrents give rise to over ten times enhanced detectivities for perovskite hybrid photodetectors, reaching over 10 13 cm Hz 1/2 W −1 (Jones) from 375 to 800 nm. These results demonstrate that the method provides a simple and facile way to boost the device performance of perovskite photovoltaics.
Computer-Aided Identification of Recognized Drugs as <i>Pseudomonas aeruginosa</i> Quorum-Sensing Inhibitors (2009)

Attenuation of Pseudomonas aeruginosa virulence by the use of small-molecule quorum-sensing inhibitors (referred to as the antipathogenic drug principle) is likely to play a role in future treatment strategies for chronic infections. In this study, structure-based virtual screening was used in a search for putative quorum-sensing inhibitors from a database comprising approved drugs and natural compounds. The database was built from compounds which showed structural similarities to previously reported quorum-sensing inhibitors, the ligand of the P. aeruginosa quorum-sensing receptor LasR, and a quorum-sensing receptor agonist. Six top-ranking compounds, all recognized drugs, were identified and tested for quorum-sensing-inhibitory activity. Three compounds, salicylic acid, nifuroxazide, and chlorzoxazone, showed significant inhibition of quorum-sensing-regulated gene expression and related phenotypes in a dose-dependent manner. These results suggest that the identified compounds have the potential to be used as antipathogenic drugs. Furthermore, the results indicate that structure-based virtual screening is an efficient tool in the search for novel compounds to combat bacterial infections.
Highly Active Methanol Dissociation Catalysts Derived from Supported Molten Salts (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHighly Active Methanol Dissociation Catalysts Derived from Supported Molten SaltsAndrew D. Schmitz, Darrell P. Eyman, and Katherine B. GloerCite this: Energy Fuels 1994, 8, 3, 729–740Publication Date (Print):May 1, 1994Publication History Published online1 May 2002Published inissue 1 May 1994https://pubs.acs.org/doi/10.1021/ef00045a030https://doi.org/10.1021/ef00045a030research-articleACS PublicationsRequest reuse permissionsArticle Views214Altmetric-Citations15LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Hyaluronic Acid and Its Derivatives in Coating and Delivery Systems: Applications in Tissue Engineering, Regenerative Medicine and Immunomodulation (2016)

As an Extracellular Matrix (ECM) component, Hyaluronic acid (HA) plays a multi-faceted role in cell migration, proliferation and differentiation at micro level and system level events such as tissue water homeostasis. Among its biological functions, it is known to interact with cytokines and contribute to their retention in ECM microenvironment. In addition to its biological functions, it has advantageous physical properties which result in the industrial endeavors in the synthesis and extraction of HA for variety of applications ranging from medical to cosmetic. Recently, HA and its derivatives have been the focus of active research for applications in biomedical device coatings, drug delivery systems and in the form of scaffolds or cell-laden hydrogels for tissue engineering. A specific reason for the increase in use of HA based structures is their immunomodulatory and regeneration inducing capacities. In this context, this article reviews recent literature on modulation of the implantable biomaterial microenvironment by systems based on HA and its derivatives, particularly hydrogels and microscale coatings that are able to deliver cytokines in order to reduce the adverse immune reactions and promote tissue healing.
Low pour hydrocarbon oil compositions. [alkylated polybenzyl polymer or copolymer] (1979)

Low pour point hydrocarbon oil compositions are prepared by incorporating in a hydrocarbon oil such as crude oil, gas oil, residual fuel oil, etc. about 0.01 to about 0.5 percent by weight of an oil-soluble alkylated polybenzyl polymer or copolymer with, for example styrene, the said polymer or copolymer having a molecular weight of about 500 to about 50,000 or more. The polymer or copolymer may be added, for example, as a hydrocarbon solution to the base hydrocarbon oil after which the final oil composition is formed by heating the components to 100/sup 0/ to 350/sup 0/F. for one hour or more with mixing. 10 claims.
Multiplex Tandem Mass Spectrometry Enzymatic Activity Assay for Newborn Screening of the Mucopolysaccharidoses and Type 2 Neuronal Ceroid Lipofuscinosis (2017)

The new multiplex assay provides a robust comprehensive newborn screening assay for the mucopolysaccharidoses. The method has been expanded to include additional lysosomal storage diseases.
Quantitation of Dimethylnitrosamine in the Whole Mouse After Biosynthesis in Vivo from Trace Levels of Precursors (1977)

A simple and highly sensitive procedure is described for the recovery and quantitative identification of nanogram quantities of preformed N-nitroso compounds in the whole mouse. This procedure has also been applied to the quantitation of N-nitroso compounds after they have been biosynthesized from trace amounts of precursors. The whole animal is frozen in liquid nitrogen and homogenized to a frozen powder; the powder is then extracted and analyzed by a thermal energy analyzer interfaced to a gas-liquid and a high-pressure liquid chromatograph.
A new paradigm for tumor immune escape: β-catenin-driven immune exclusion (2015)

Increasing evidence is emerging that immunotherapeutic interventions, including checkpoint blockade, are predominantly effective in patients with a pre-existing T cell-inflamed tumor microenvironment. Understanding the mechanisms leading to a non-T cell-inflamed microenvironment are crucial for the development of novel treatment modalities to expand the fraction of patients benefiting from immunotherapy. Based on the hypothesis that one source of inter-patient heterogeneity would lie at differential activation of specific oncogene pathways within the tumor cells themselves, our group recently observed that tumor-cell intrinsic activation of the WNT/β-catenin pathway correlates with absence of T cells from the microenvironment in metastatic melanoma. Genetically-engineered mouse models confirmed a causal relationship, via a mechanism of failed Batf3-lineage dendritic cell recruitment. Hence, tumor cell-intrinsic activation of β-catenin is the first oncogenic pathway demonstrated to exclude the anti-tumor immune response, revealing a potential therapeutic target for improving immunotherapy responsiveness.