gebhart/patrepeval huggingface dataset:
Development and testing of a novel sulfur dioxide sonde (2022)

Abstract. A novel technique has been developed to measure sulfur dioxide (SO2) using a modification of the existing electrochemical concentration cell (ECC) ozonesonde technology. The current sonde-based method to measure SO2 (i.e., the dual-sonde approach) involves launching two ozonesondes together, with one of the sondes having a filter to remove SO2 at the inlet. The SO2 profile is determined by taking the difference between the measurements from the two instruments. The dual-sonde method works well in typical tropospheric conditions when [O3]>[SO2] but saturates when [SO2]>[O3] and has large uncertainties in the upper troposphere and lower stratosphere that would limit its effectiveness in measuring SO2 from an explosive volcanic eruption. Due to these limitations, several modifications were made to create a single-sonde system that would directly measure SO2 (i.e., the SO2 sonde). These modifications included (1) a positively biased ECC current, (2) the addition of an O3 removal filter, and (3) the addition of a sample dryer. The SO2 sonde measures SO2 as a reduction in the cell current. There was a strong correlation (r2>0.94) between the SO2 sonde and a Thermo 43c analyzer during controlled laboratory tests and pre-flight tests. Varying humidity levels affected the SO2 sonde's sensitivity (avg =84.6±31.7 ppbv µA−1, 1σ RSD =37 %) during initial field tests, which was resolved by adding a sample dryer upstream of the O3 removal filter and pump inlet. This modification significantly reduced the variability and increased the sensitivity of the SO2 measurements (avg =47±5.8 ppbv µA−1, 1σ RSD =12 %). Field tests included measurements near Kīlauea volcano (before and during the 2018 eruption of the Lower East Rift Zone), Costa Rica's Turrialba volcano, and anthropogenic plumes from the Athabasca oil sands region of Alberta, Canada. This single-SO2-sonde system is an effective, inexpensive instrument for measuring both ground-based and vertical profiles of SO2 from anthropogenic and natural sources (i.e., volcanic eruptions) over a wide range of concentrations.
Novel amphiphilic hyaluronic acid derivatives as injectable hydrogels for controlled drug release (2016)

Frontiers Events is a rapidly growing calendar management system dedicated to the scheduling of academic events. This includes announcements and invitations, participant listings and search functionality, abstract handling and publication, related events and post-event exchanges. Whether an organizer or participant, make your event a Frontiers Event!
Novel Therapeutic Game Controller for Telerehabilitation of Spastic Hands: Two Case Studies (2019)

Spasticity or increase in muscle tone presents challenges during post-stroke rehabilitation. The use of off-the-shelf game controllers is problematic for individuals with hand spasticity. The novel BrightBrainer Grasp (BBG) controller was designed to overcome these barriers when used in virtual rehabilitation of individuals post-stroke. The custom controller measures power grasp, finger extension, wrist position and orientation, as well as 3D hand position. It is designed to minimize friction when used by those with no gravity bearing. Two controllers were used in bilateral training. This paper presents a detailed description of the BBG controllers and their interaction with the BrightBrainer™ gaming system. Two case reports of individuals chronic post-stroke who participated in a 4-week telerehabilitation intervention are included.
Computer Simulations of Electrokinetic Transport in Microfabricated Channel Structures (1998)

A mathematical model describing electrokinetically driven mass transport phenomena in microfabricated chip devices is presented in this paper. The model accounts for principal material transport mechanisms such as electrokinetic migration (electrophoresis and electroosmosis) and diffusion. A computer code that implements the model is capable of simulating transport of materials during electrokinetic manipulation in 2-D channel structures. The computer code allows arbitrary channel geometries with various boundary conditions for the electric field and the sample concentration. Two fundamental microfluidic chip elements, a cross and a mixing tee, are of particular interest. An electrokinetic focusing experiment using a cross structure and mixing in a tee structure are simulated. Simulations revealed an optimum focusing voltage for which the ratio of sample concentration to sample width is maximized. They also verified that the mixing tee provides very accurate dilution/mixing characteristics for both charged and neutral samples. Good agreement between simulated and experimental data verified the accuracy of the mathematical model.
Modeling Subsurface Upflow Wetlands Systems for Wastewater Effluent Treatment (2010)

Constructed wetlands have been popular in ecological engineering regime; yet, modeling the physical, chemical, and biological processes within these wetlands is a long-standing challenge in the past decades. In concert with our field-scale pilot testing of a new-generation subsurface upflow wetland (SUW) system, this article highlights an advancement of modeling the SUW system with a layer-structured compartmental simulation model. This is the first wetland model of its kind to address the complexity between plant nutrient uptake and medium sorption. Such a system dynamics model using STELLA® as a means for a graphical formulation was applied to illustrate the essential mechanism of the nitrification and denitrification processes within a sorption medium-based SUW system, which can be recognized as one of the major passive on-site wastewater treatment technologies in this decade. Model calibration and validation received fairly good R-squared values of 0.9998 and 0.9644, respectively. Such good agreement with the measured data confirms that the developed system dynamics model may provide a reliable tool for designing this particular type of constructed wetland. This work also entails the significant movement of linking green building with green infrastructure as part of the urbanization for nature.
<title>Propagation diversity enhancement to the subspace-based line detection algorithm</title> (1995)

In the context of fitting straight lines to noisy images, the subspace-based line detection algorithm (SLIDE) offers two benefits over the conventional Hough transform method: low computational complexity and high resolution of the estimates. These improvements are due to the fact that the line fitting problem is converted to an equivalent problem of fitting exponentials to a time series, which can then be solved efficiently by using subspace methods like ESPRIT. The SLIDE algorithm establishes this equivalence by transforming the two dimensional binary image to a single observation vector using a propagation scheme. The difficulty with having a single observation vector in this approach is that the total number of snapshots may not be adequately large. This limits the estimation accuracy and degrades the performance of the detection algorithm (which estimates the number of present lines in the image). In this paper we propose to utilize multiple observation vectors to circumvent the problem of inadequate number of snapshots. The challenge with the multiple observation vector approach is how to combine these vectors to form a covariance matrix that possesses the desired structure. We overcome this difficulty by considering only a specific set of observation vectors along with an interleaving technique. Simulation results show that this technique significantly improves the efficiency of the detection algorithm as well as the accuracy of the estimates of the line angles.
YKL-40 expression in naevocellular naevi, carcinomas and melanomas of the skin (2006)

18019 Background: Elevated serum levels of the protein YKL-40 are associated with a poor prognosis in several solid tumors including melanoma (H. Schmidt, JCO 2006, Cancer 2006 in press). YKL-40 is secreted by cancer cells, macrophages and neutrophils. The function of YKL-40 is only poorly understood. It may be a growth or differentiation factor, play a role in angiogenesis or protect against apoptosis. The aim was to describe the tissue expression of YKL-40 in naevocellular naevi, carcinomas and melanomas of the skin by immunohistochemistry. Methods: Paraffin-embedded tissue sections from 40 patients with different naevocellular naevi, carcinomas and melanomas of the skin were developed with EnVision+ System-HRP K4007 (DakoCytomation) using a monoclonal antibody against YKL-40. The intensity of YKL-40 staining was scored using a semi-quantitative method. Results: YKL-40 protein expression appeared as a cytoplasmic, granular staining with no staining of membranes, nuclei or extracellular matrix. In normal skin the basal epithelial layer stained weakly positive. Melanocytes and melanophages stained negative. Macrophages and leucocytes stained positive. Hair follicles, sebaceous glands and sweat glands stained positive. Three basal cell carcinomas all stained positive. In 10 squamous cell carcinomas, the epidermal components stained positive and the invasive tumor islands were negative. In 3 keratoacanthomas, the epithelial components as well as the infiltrative tumor islands stained positive. In naevi (2 junctional, 5 compound and 1 intradermal) the epithelial components stained positive, the intradermal components stained negative. In melanomas the tumor cells stained positive in 9 of 10 specimens. Both the epidermal and the invasive components of melanomas stained positive. Three melanoma metastases all stained positive. Conclusions: YKL-40 is expressed in normal skin and in benign and malignant lesions of the skin. Generally, YKL-40 expression is increased in cells of high activity, although the invasive tumor islands of squamous cell carcinomas stain negative. In melanomas, the tumor cells may be a source of the elevated YKL-40 serum levels observed in these patients. No significant financial relationships to disclose.
Synthesis and Antibacterial Activity of Pyrroloaryl‐Substituted Oxazolidinones. (2004)

Abstract For Abstract see ChemInform Abstract in Full Text.
Amperometric sensor for carbon dioxide: design, characteristics, and performance (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAmperometric sensor for carbon dioxide: design, characteristics, and performanceJohn. Evans, Derek. Pletcher, P. Richard G. Warburton, and T. Kim. GibbsCite this: Anal. Chem. 1989, 61, 6, 577–580Publication Date (Print):March 15, 1989Publication History Published online1 May 2002Published inissue 15 March 1989https://doi.org/10.1021/ac00181a016Request reuse permissionsArticle Views268Altmetric-Citations21LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (517 KB) Get e-Alertsclose Get e-Alerts
Blood flow velocity quantification using split-spectrum amplitude-decorrelation angiography with optical coherence tomography (2013)

The split-spectrum amplitude-decorrelation angiography (SSADA) algorithm was recently developed as a method for imaging blood flow in the human retina without the use of phase information. In order to enable absolute blood velocity quantification, in vitro phantom experiments are performed to correlate the SSADA signal at multiple time scales with various preset velocities. A linear model relating SSADA measurements to absolute flow velocities is derived using the phantom data. The operating range for the linear model is discussed along with its implication for velocity quantification with SSADA in a clinical setting.
An Object-oriented Tool for Clinical Queries (2000)

Clinical data repositories are viewed as digital goldmines for both clinical researchers and managed care utilization reviewers. Querying the data is, nevertheless, challenging due to the heterogeneity of the sources and the lack of intuitive interfaces for question makers. We present a prototype of a query tool that uses the object metaphor to make sense to users and database administrators alike.
Interfacial adhesion of lignocellulosic materials in polymer composites: an overview (1993)

Abstract Cellulosic materials have long been used as cost-cutting fillers in the plastic industry. Among the various factors which determine the final performance of the composite materials depend, to a large extent, on the adhesion between the polymer matrix and the reinforcements, and, therefore, on the quality of the interface. In fact, the majority of cellulosic raw materials are lignocellulosics of different polarity to plastics, and due to this divergent behavior, the adhesion between cellulosic materials and polymer matrices is very poor. However, a sufficient degree of interaction or adhesion between the surface of the cellulosic materials and matrix resin is usually desired to achieve an optimum performance of the end-product. In many cases surface modification of the cellulosics or the matrix resins, using various additives, vinyl monomers, or coupling agents, are considered to be essential to achieve this goal. The present paper surveys research work published in this field with special emphasis on the cellulosic materials' surface chemistry, morphology, as well as interfacial properties of the composites in order to elucidate the role of surface treatments. In order to elucidate the mechanism of interaction on molecular level, it is necessary to employ various techniques, such as spectroscopy that can measure surface events. In fact, the complexity of the interphase region requires a variety of characterization methods for the thorough understanding of the physical and chemical nature of this region. Moreover, a proper combination of different techniques is necessary to provide a true picture of the interphase. Keywords: Composite interfacereinforcementsurface modificationsurface characterizationreview
Processes for non-destructive transfer of graphene: widening the bottleneck for industrial scale production (2015)

The exceptional charge-transport, mechanical, and barrier properties of graphene are well known. High-quality films of single-layer graphene produced over large areas, however, are extremely expensive. The high cost of graphene precludes its use in industries-such as transparent electrodes and flexible packaging-that might take full advantage of its properties. This minireview presents several strategies for the transfer of graphene from the substrates used for growth to substrates used for the final application. Each strategy shares the characteristic of being non-destructive: that is, the growth substrate remains reusable for further synthesis of new graphene. These processes have the potential to lower significantly the costs of manufacturing graphene, to increase production yields, and to minimize environmental impact. This article is divided into sections on (i) the synthesis of high-quality single-layer graphene and (ii) its non-destructive transfer to a host substrate. Section (ii) is further divided according to the substrate from which graphene is transferred: single-crystalline wafers or flexible copper foils. We also comment, wherever possible, on defects produced as a result of the transfer, and potential strategies to mitigate these defects. We conclude that several methods for the green synthesis and transfer of graphene have several of the right characteristics to be useful in industrial scale production.
Texas Hold 'Em algorithms for distributed compressive sensing (2010)

This paper develops a new class of algorithms for signal recovery in the distributed compressive sensing (DCS) framework. DCS exploits both intra-signal and inter-signal correlations through the concept of joint sparsity to further reduce the number of measurements required for recovery. DCS is well-suited for sensor network applications due to its universality, computational asymmetry, tolerance to quantization and noise, and robustness to measurement loss. In this paper we propose recovery algorithms for the sparse common and innovation joint sparsity model. Our approach leads to a class of efficient algorithms, the Texas Hold 'Em algorithms, which are scalable both in terms of communication bandwidth and computational complexity.
Optimizing a Biocatalyst for Improved NAD(P)H Regeneration: Directed Evolution of Phosphite Dehydrogenase (2006)

Cofactor regeneration is an important solution to the problem of implementing complex cofactor requiring enzymatic reactions at the industrial scale. NAD(P)H-dependent oxidoreductases are highly valuable biocatalysts, but the high cost of the nicotinamide cofactors necessitates in situ cofactor regeneration for preparative applications. Here we report the use of directed evolution to enhance the industrially important properties of phosphite dehydrogenase for NAD(P)H regeneration. A two-tiered sorting method of selection and screening was used in conjunction with random and rational mutagenesis. Following six rounds of directed evolution, soluble expression in E. coli was increased more than 3-fold, while the turnover rate was increased about 2-fold, effectively lowering the cost of the enzyme by >6-fold. Large-scale production of the final mutant enzyme by fermentation resulted in approximately 6-times higher yield (Units/Liter) than the WT enzyme. The enhancements of PTDH were independent of expression vector and E. coli strain utilized. The advantage of the final mutant over the WT enzyme was demonstrated using the industrially relevant bioconversion of trimethylpyruvate to L-tert-leucine. The mutations discovered are discussed in the context of a three dimensional structural model and the resulting changes in kinetics and soluble expression. The engineered phosphite dehydrogenase has great potential for NAD(P)H regeneration in industrial biocatalysis.
A simple two-step purification of protease nexin (1986)

This paper describes a simple purification procedure for protease nexin, a serine proteinase inhibitor secreted by cultured human fibroblasts that regulates proteinase activity at and near the cell surface. The first step in the procedure takes advantage of the high-affinity binding of protease nexin to dextran sulphate-Sepharose. This step eliminates the need for prior concentration of the serum-free fibroblast-conditioned medium, since protease nexin binds to the resin in the presence of physiological saline. The use of dextran sulphate also provides an affinity resin with considerably less variability than the heparin-based resins previously used. Final purification to homogeneity involves a combination of DEAE-Sepharose in-line with dextran sulphate-Sepharose to simultaneously purify and concentrate the protein. Purified protease nexin is shown by Ouchterlony analysis and peptide mapping to be immunologically and structurally distinct from antithrombin III and heparin cofactor II, two plasma proteinase inhibitors with similar properties.
Thermocatalytic CO{sub 2}-Free Production of Hydrogen from Hydrocarbon Fuels - Final Report for the Period August 1999 - September 2000 (2000)

The overall objective of this work is to develop a novel process for CO{sub 2}-free production of hydrogen via thermocatalytic decomposition (pyrolysis) of hydrocarbon fuels as a viable alternative to the conventional processes of methane steam reforming or partial oxidation. The objective of Phase I work was to demonstrate the technical feasibility of CO{sub 2}-free production of hydrogen and carbon from different hydrocarbons, including methane, propane and gasoline.
A [beta]-Glucosidase from Lodgepole Pine Xylem Specific for the Lignin Precursor Coniferin (1995)

Coniferin, the glucoside of the monolignol coniferyl alcohol, accumulates to high levels in gymnosperms during spring-cambial reactivation. A cinnamyl alcohol glucoside/beta-glucosidase system is thought to play a key role in lignification by releasing the monolignol aglycones. Investigation of such an enzyme system in the xylem of Pinus contorta var latifolia Engelm. revealed two major beta-glucosidases. One efficiently hydrolyzed the native substrate, coniferin, and the other was more active against synthetic glucosides. The coniferin beta-glucosidase was purified to apparent homogeneity using anion exchange, hydrophobic interaction, and size-exclusion chromatography. The apparent native molecular weight was estimated to be 60,000. A dominant 28-kD protein and a minor 24-kD protein were detected in the purified preparation following sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Immunological evidence from polyclonal antibodies directed against the synthetic N-terminal peptide of the 24-kD protein suggested that the native protein is a dimer of 28-kD subunit size. The N-terminal sequence showed that coniferin beta-glucosidase has high homology to known plant beta-glucosidases. Coniferin, syringin, and a synthetic coniferin analog were preferred substrates for the coniferin beta-glucosidase. In situ localization using the chromogenic coniferin analog showed the exclusive presence of beta-glucosidase activity in the differentiating xylem, similar to peroxidase activity.
Recursive all-lag reference-code correlators (2000)

An all-lag reference code correlator generates an all-lag even-or odd-correlation vector at a rate equal to the rate of incoming data samples. Direct implementation of an all-lag reference-code correlator requires N parallel correlators, and the resultant degree of complexity is of the order N/sup 2/, where N is the length of the reference code. This paper derives two recursive forms for all-lag reference-code correlators. One generates all lag even correlation and the other one generates all-lag odd correlation. It Is shown that the proposed recursive all-lag reference-code correlator can be implemented with a complexity approximately equal to that of a single parallel correlator. That is, the degree of complexity of the proposed recursive all-lag reference-rode correlator is of the order N. Thus, substantial reduction in the implementation complexity is achieved.