gebhart/patrepeval huggingface dataset:
Design of phased arrays in terms of random subarrays (1994)

Analysis and systematic design of uniform phased arrays with subarrays of unequal sizes are absent from the literature, in spite of the appeal of such architectures to wide-bandwidth beam steering. Unequally sized subarrays are expected to outperform identical, contiguous subarrays in terms of array grating lobes, A uniform linear array that is divided into contiguous subarrays of random sizes is studied. Each array element is connected to a phase shifter, and each subarray is implemented with a common time delayer. Closed-form expressions for the average array factor and the variance of the array factor are developed. These expressions enable the formulation of a design procedure that includes the estimation of the peak-grating-lobe level in terms of the probability that the grating lobes will exceed a desired level.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Growth of murine multipotent stem cells in a simple "serum-free" culture system: role of interleukin-3, erythropoietin, and hemin. (1988)

The growth requirements of normal murine marrow-derived multipotent stem cells (CFU-GEMM) in a simple clonal cell culture system substantially devoid of exogenous serum proteins was assessed. The ability of murine interleukin-3 (Il-3), recombinant human erythropoietin (rEPO), and a crystalline preparation of the protoporphyrin hemin to support colony growth in "serum-free" cultures was examined by titration. The results suggest that both Il-3 and hemin are limiting for multipotential colony growth in "serum-free" cultures, but that EPO is not. In addition, the "sensitivity" of CFU-GEMM to each growth factor appeared to increase in the "serum-free" environment as evidenced by a "shift-to-the-left" in all the titration curves. Nearly half of the GEMM colonies grew to full maturity in the absence of exogenous EPO. Given the optimal concentration of each growth factor, high colony growth was consistently observed in the "serum-free" cultures, with a range from 65% to 119% of the serum control level. It is therefore concluded that supplementation of murine marrow cultures with Il-3 and hemin alone may provide the necessary setting for studying the factors that modulate the growth of multipotent stem cells in a serum-free environment.
Transboundary pollution: Persistent organochlorine pesticides in migrant birds of the Southwestern United States and Mexico (1997)

Abstract The hypothesis that migratory birds accumulate persistent organochlorine pesticides (POPs) during the winter in Latin America has been prevalent for many years, particularly since 1,1,1-trichloro-2,2–bis(p-chlorophenyl)ethane (DDT) was banned in the United States in 1972. It has been suggested that peregrine falcons (Falco peregrinus), black-crowned night herons (Nycticorax nycticorax), white-faced ibises (Plegadis chihi), various migratory waterfowl and shorebirds, and other avian species accumulate higher concentrations of POPs while on migration or on their wintering grounds in Latin America. Nonetheless, the data obtained thus far are limited, and there is no clear pattern to suggest that such accumulation occurs on a widespread basis. In this review wildlife contaminant studies conducted along the U.S.-Mexico border and throughout Mexico are discussed. The results for the most part seem to indicate that no major accumulation of 2,2-bis(p-chlorophenyl)-1,1-dichloroethylene) (DDE), the most persistent organochlorine compound, has occurred or been reported for most parts of Mexico. The majority of the DDE values in birds from Mexico were similar to those reported in birds from the southwestern United States during the same years. More work needs to be done, particularly in those cotton-producing areas of Mexico where DDT was applied heavily in the past (e.g., Chiapas and Michoacan). Because DDT is still used for malaria control and may still be used in agriculture in Chiapas, this state is probably the one where most migrant species would still be at a significant risk of increased accumulation of DDE and DDT.
Acid-catalyzed amino-migration of O-phenylhydroxylamines (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAcid-catalyzed amino-migration of O-phenylhydroxylaminesNaoki Haga, Yasuyuki Endo, Kenichiro Kataoka, Kentaro Yamaguchi, and Koichi ShudoCite this: J. Am. Chem. Soc. 1992, 114, 25, 9795–9806Publication Date (Print):December 1, 1992Publication History Published online1 May 2002Published inissue 1 December 1992https://doi.org/10.1021/ja00051a012Request reuse permissionsArticle Views1574Altmetric-Citations32LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (2 MB) Get e-Alertsclose Get e-Alerts
Draft Genome Sequence of Escherichia coli Strain Nissle 1917 (Serovar O6:K5:H1) (2013)

We announce the availability of the 5.023-Mbp high-quality draft assembly of the Escherichia coli strain Nissle 1917 (serovar O6:K5:H1) genome. Short genomic segments from this important probiotic strain have been available in public databases, but the full genome sequence has remained inaccessible. Thus, high-coverage, whole genome sequencing of E. coli Nissle 1917 is presented herein. Reannotation and metabolic reconstruction will enable comparative genomics analysis and model-guided predictions of genetic manipulations leading to increased production of the K5 capsular polysaccharide known as N-acetyl heparosan, a precursor to the anticoagulant pharmaceutical heparin.
Coherent forecasting for count time series using Box–Jenkins's AR(<i>p</i>) model (2015)

During the last three decades, integer‐valued autoregressive process of order p [or INAR( p )] based on different operators have been proposed as a natural, intuitive and maybe efficient model for integer‐valued time‐series data. However, this literature is surprisingly mute on the usefulness of the standard AR( p ) process, which is otherwise meant for continuous‐valued time‐series data. In this paper, we attempt to explore the usefulness of the standard AR( p ) model for obtaining coherent forecasting from integer‐valued time series. First, some advantages of this standard Box–Jenkins's type AR( p ) process are discussed. We then carry out our some simulation experiments, which show the adequacy of the proposed method over the available alternatives. Our simulation results indicate that even when samples are generated from INAR( p ) process, Box–Jenkins's model performs as good as the INAR( p ) processes especially with respect to mean forecast. Two real data sets have been employed to study the expediency of the standard AR( p ) model for integer‐valued time‐series data.
Stable scheduling policies for fading wireless channels (2005)

We study the problem of stable scheduling for a class of wireless networks. The goal is to stabilize the queues holding information to be transmitted over a fading channel. Few assumptions are made on the arrival process statistics other than the assumption that their mean values lie within the capacity region and that they satisfy a version of the law of large numbers. We prove that, for any mean arrival rate that lies in the capacity region, the queues will be stable under our policy. Moreover, we show that it is easy to incorporate imperfect queue length information and other approximations that can simplify the implementation of our policy.
EDA for IC Implementation, Circuit Design, and Process Technology (2011)

Design Flows. Logic Synthesis. Power Analysis and Optimization from Circuit to Register Transfer Levels. Equivalence checking. Digital Layout - Placement. Static Timing Analysis. Structured Digital Design. Routing. Exploring Challenges of Libraries for Electronic Design. Design Closure. Tools for Chip-Package Codesign. Design Databases. FPGA Synthesis and Physical Design. Simulation of Analog and Radio Frequency Circuits and Systems. Simulation and Modeling for Analog and Mixed-Signal Integrated Circuits. Layout Tools for Analog ICs and Mixed-Signal SoCs. Design Rule Checking. Resolution Enhancement Technology and Mask Data Preparation. Design for Manufacturability in the Nanometer Era. Power Supply Network Design and Analysis. Noise Considerations in Digital ICs. Layout Extraction. Mixed-Signal Noise Coupling in System-on-Chip Design: Modeling, Analysis and Validation. Process Simulation. Device Modeling: From Physics to Electrical Parameter Extraction. High-Accuracy Parasitic Extraction.
A scalable metal-organic framework as a durable physisorbent for carbon dioxide capture (2021)

Metal-organic frameworks (MOFs) as solid sorbents for carbon dioxide (CO<sub>2</sub>) capture face the challenge of merging efficient capture with economical regeneration in a durable, scalable material. Zinc-based Calgary Framework 20 (CALF-20) physisorbs CO<sub>2</sub> with high capacity but is also selective over water. Competitive separations on structured CALF-20 show not just preferential CO<sub>2</sub> physisorption below 40% relative humidity but also suppression of water sorption by CO<sub>2</sub>, which was corroborated by computational modeling. CALF-20 has a low enthalpic regeneration penalty and shows durability to steam (>450,000 cycles) and wet acid gases. It can be prepared in one step, formed as composite materials, and its synthesis can be scaled to multikilogram batches.
Characterization of Escherichia coli ATP synthase .beta.-subunit mutations using a chromosomal delection strain (1991)

(1) We constructed Escherichia coli strain JP17 with a deletion in the ATP synthase beta-subunit gene. JP17 is completely deficient in ATP synthase activity and expresses no beta-subunit. Expression of normal beta-subunit from a plasmid restores haploid levels of ATP synthase in membranes. JP17 was shown to be efficacious for studies of beta-subunit mutations. Site-directed mutants were studied directly in JP17. Randomly generated chromosomal mutants were identified by PCR and DNA sequencing, cloned, and expressed in JP17. (2) Eight novel mutations occurring within the putative catalytic nucleotide-binding domain were characterized with respect to their effects on catalysis and structure. The mutations beta C137S, beta G152D, beta G152R, beta E161Q, beta E161R, and beta G251D each impaired catalysis without affecting enzyme assembly or oligomeric structure and are of interest for future studies of catalytic mechanism. The mutations beta D301V and beta D302V, involving strongly conserved carboxyl residues, caused oligomeric instability of F1. However, growth characteristics of these mutants suggested that neither carboxyl side chain is critical for catalysis. (3) The mutations beta R398C and beta R398W rendered ATP synthase resistant to aurovertin, giving strong support to the view that beta R398 is a key residue in the aurovertin-binding site. Neither beta R398C or beta R398W impaired catalysis significantly.
Strategy for selecting and characterizing linker peptides for CBM9‐tagged fusion proteins expressed in <i>Escherichia coli</i> (2007)

The influence of linker design on fusion protein production and performance was evaluated when a family 9 carbohydrate-binding module (CBM9) serves as the affinity tag for recombinant proteins expressed in Escherichia coli. Two bioinformatic strategies for linker design were applied: the first identifies naturally occurring linkers within the proteome of the host organism, the second involves screening peptidases and their known specificities using the bioinformatics software MEROPS to design an artificial linker resistant to proteolysis within the host. Linkers designed using these strategies were compared against traditional poly-glycine linkers. Although widely used, glycine-rich linkers were found by tandem MS data to be susceptible to hydrolysis by E. coli peptidases. The natural (PT)(x)P and MEROPS-designed S(3)N(10) linkers were significantly more stable, indicating both strategies provide a useful approach to linker design. Factor X(a) processing of the fusion proteins depended strongly on linker chemistry, with poly(G) and S(3)N(10) linkers showing the fastest cleavage rates. Luminescence resonance energy transfer studies, used to measure average distance of separation between GFP and Tb(III) bound to a strong calcium-binding site of CBM9, revealed that, for a given linker chemistry, the separation distance increases with increasing linker length. This increase was particularly large for poly(G) linkers, suggesting that this linker chemistry adopts a hydrated, extended configuration that makes it particularly susceptible to proteolysis. Differential scanning calorimetry studies on the PT linker series showed that fusion of CBM9 to GFP did not alter the T(m) of GFP but did result in a destabilization, as seen by both a decrease in T(m) and DeltaH(cal), of CBM9. The degree of destabilization increased with decreasing length of the (PT)(x)P linker such that DeltaT(m) = -8.4 degrees C for the single P linker.
Acyclic nucleoside analogs: synthesis of open-ring riboside or deoxyriboside analogs lacking C(3') or the C(3')-C(4') bond (1979)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAcyclic nucleoside analogs: synthesis of open-ring riboside or deoxyriboside analogs lacking C(3') or the C(3')-C(4') bondJerry D. Bryant, Gene E. Keyser, and Jorge R. BarrioCite this: J. Org. Chem. 1979, 44, 21, 3733–3734Publication Date (Print):October 1, 1979Publication History Published online1 May 2002Published inissue 1 October 1979https://pubs.acs.org/doi/10.1021/jo01335a033https://doi.org/10.1021/jo01335a033research-articleACS PublicationsRequest reuse permissionsArticle Views152Altmetric-Citations32LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Recombinant Human Type II Collagens with Low and High Levels of Hydroxylysine and Its Glycosylated Forms Show Marked Differences in Fibrillogenesis in Vitro (1999)

Type II collagen is the main structural component of hyaline cartilages where it forms networks of thin fibrils that differ in morphology from the much thicker fibrils of type I collagen. We studied here in vitro the formation of fibrils of pepsin-treated recombinant human type II collagen produced in insect cells. Two kinds of type II collagen preparation were used: low hydroxylysine collagen having 2.0 hydroxylysine residues/1,000 amino acids, including 1.3 glycosylated hydroxylysines; and high hydroxylysine collagen having 19 hydroxylysines/1,000 amino acids, including 8.9 glycosylated hydroxylysines. A marked difference in fibril formation was found between these two kinds of collagen preparation, in that the maximal turbidity of the former was reached within 5 min under the standard assay conditions, whereas the absorbance of the latter increased until about 600 min. The critical concentration with the latter was about 10-fold, and the absorbance/microgram collagen incorporated into the fibrils was about one-sixth. The morphology of the fibrils was also different, in that the high hydroxylysine collagen formed thin fibrils with essentially no interfibril interaction or aggregation, whereas the low hydroxylysine collagen formed thick fibrils on a background of thin ones. The data thus indicate that regulation of the extents of lysine hydroxylation and hydroxylysine glycosylation may play a major role in the regulation of collagen fibril formation and the morphology of the fibrils.
Catalytic Steam and Partial Oxidation Reforming of Liquid Fuels for Application in Improving the Efficiency of Internal Combustion Engines (2018)

This study investigated the potential for catalytically reforming liquid fuels in a simulated exhaust gas recirculation (EGR) mixture loop for the purpose of generating reformate that could be used to increase stoichiometric combustion engine efficiency. The experiments were performed on a simulated exhaust flow reactor using a Rh/Al2O3 reformer catalyst, and the fuels evaluated included iso-octane, ethanol, and gasoline. Both steam reforming and partial oxidation reforming were examined as routes for the production of reformate. Steam reforming was determined to be an ineffective option for reforming in an EGR loop, because of the high exhaust temperatures (in excess of 700 °C) required to produce adequate concentrations of reformate, regardless of fuel. However, partial oxidation reforming is capable of producing hydrogen concentrations as high as 10%–16%, depending on fuel and operating conditions in the simulated EGR gas mixture. Meanwhile, measurements of total fuel enthalpy retention were shown to have favorable energetics under a range of conditions, although a tradeoff between fuel enthalpy retention and reformate production was observed. Of the three fuels evaluated, iso-octane exhibited the best overall performance, followed by ethanol and then gasoline. Overall, it was found that partial oxidation reforming of liquid fuels in a simulated EGR mixture over the Rh/Al2O3 catalyst demonstrated sufficiently high reformate yields and favorable energetics to warrant further evaluation in the EGR system of a stoichiometric combustion engine.
ItemRank: a random-walk based scoring algorithm for recommender engines (2007)

Recommender systems are an emerging technology that helps consumers to find interesting products. A recommender system makes personalized product suggestions by extracting knowledge from the previous users interactions. In this paper, we present ItemRank, a random-walk based scoring algorithm, which can be used to rank products according to expected user preferences, in order to recommend top-rank items to potentially interested users. We tested our algorithm on a standard database, the MovieLens data set, which contains data collected from a popular recommender system on movies, that has been widely exploited as a benchmark for evaluating recently proposed approaches to recommender system (e.g. [Fouss et al., 2005; Sarwar et al., 2002]). We compared ItemRank with other state-of-the-art ranking techniques (in particular the algorithms described in [Fouss et al., 2005]). Our experiments show that ItemRank performs better than the other algorithms we compared to and, at the same time, it is less complex than other proposed algorithms with respect to memory usage and computational cost too.
Audiology telemedicine (2007)

Various real-time telemedicine applications have been investigated in audiology, including pure tone audiometry, otoacoustic emission testing, auditory brainstem response recordings, hearing aid fitting and video-otoscopy. Store-and-forward applications have usually been used to transmit basic patient data including case history information and hearing screening results, although both video-nystagmography and video-otoscopy have been piloted. Remote access to computerized equipment is relevant to audiology telemedicine, although there have been few reports of the use of application sharing using computerized audiology equipment. In a pilot trial of real-time telemedicine, both pure tone and speech audiometry measures were provided remotely through application sharing. Audiology telemedicine appears promising, but it is at an early stage of development and many areas such as its cost effectiveness, patient acceptance and test efficacy require systematic investigation.
Online retail : service quality derivation, market segmentation and organisational analysis. (2006)

The recent rise of the internet as a commercial trading channel has left retail marketers facing several challenges. As in any marketplace, customer intelligence is the lifeblood of organisational success online, yet no thoroughly tested and validated model exists to reliably capture customer service requirements. Traditional service quality models are an insufficient and inflexible means to capture the unique nature of the internet medium while those emergent models of online behaviour developed thus far have typically been of limited scope, sample size, sample breadth and not validated in continued practice. Beyond the problem of identifying customer demands, there remains a problem of how to group together customers for segmentation purposes. In the contemporary marketplace as a whole there is growing fragmentation and individuality with demographics no longer precise enough to be useful beyond describing broad definitions of product class users. E-businesses also face a pressing challenge in addressing customer alignment in the 'value creating' marketing and operations departments. There is a need to move beyond the limiting scope of only considering marketing in relation to customer focus and to incorporate a wider consideration of organisational focus with true measures of customer requirements. Within this thesis each of these issues is addressed. With the support and collaboration of four internet companies, one of the largest surveys of online customers undertaken to date has been completed (n-3403). This has allowed for the construction of a new model of online customer service demands, validated with confirmatory factor analysis, generating a nine factor solution that comprehensively describes customers service demands. Secondly, a wide range of situational factors have been analysed for their suitability as a means of segmenting the marketplace. Structural equation modelling has provided a strong finding that finreripral measures account for far greater variance in customer demands than demographics, confirming the limited usefulness of demographics online and providing a superior replacement. An analysis of marketing and operations personnel in the four supporting companies also provided evidence that marketers were better at understanding customer requirements than their operations colleagues and that in all companies a generally good understanding of customers had resulted in high levels of customer satisfaction. Overall, this body of work stands apart in terms of holism of analysis (customer service quality, segmentation and organisational understanding), depth of analysis (extensive literature review and generation}, depth of research (sample size of n-3403) and rigour of analysis (iterative statistical process) making contributions to the academic body of knowledge and nature of managerial practice in the areas of online retail customer service, market segmentation and organisational analysis.