gebhart/patrepeval huggingface dataset:
Mapping Urban Areas Using a Combination of Remote Sensing and Geolocation Data (2019)

Urban areas are essential to daily human life; however, the urbanization process also brings about problems, especially in China. Urban mapping at large scales relies heavily on remote sensing (RS) data, which cannot capture socioeconomic features well. Geolocation datasets contain patterns of human movement, which are closely related to the extent of urbanization. However, the integration of RS and geolocation data for urban mapping is performed mostly at the city level or finer scales due to the limitations of geolocation datasets. Tencent provides a large-scale location request density (LRD) dataset with a finer temporal resolution, and makes large-scale urban mapping possible. The objective of this study is to combine multi-source features from RS and geolocation datasets to extract information on urban areas at large scales, including night-time lights, vegetation cover, land surface temperature, population density, LRD, accessibility, and road networks. The random forest (RF) classifier is introduced to deal with these high-dimension features on a 0.01 degree grid. High spatial resolution land cover (LC) products and the normalized difference built-up index from Landsat are used to label all of the samples. The RF prediction results are evaluated using validation samples and compared with LC products for four typical cities. The results show that night-time lights and LRD features contributed the most to the urban prediction results. A total of 176,266 km2 of urban areas in China were extracted using the RF classifier, with an overall accuracy of 90.79% and a kappa coefficient of 0.790. Compared with existing LC products, our results are more consistent with the manually interpreted urban boundaries in the four selected cities. Our results reveal the potential of Tencent LRD data for the extraction of large-scale urban areas, and the reliability of the RF classifier based on a combination of RS and geolocation data.
<title>Self-correcting 100-font classifier</title> (1994)

We have developed a practical scheme to take advantage of local typeface homogeneity to improve the accuracy of a character classifier. Given a polyfont classifier which is capable of recognizing any of 100 typefaces moderately well, our method allows it to specialize itself automatically to the single -- but otherwise unknown -- typeface it is reading. Essentially, the classifier retrains itself after examining some of the images, guided at first by the preset classification boundaries of the given classifier, and later by the behavior of the retrained classifier. Experimental trials on 6.4 M pseudo-randomly distorted images show that the method improves on 95 of the 100 typefaces. It reduces the error rate by a factor of 2.5, averaged over 100 typefaces, when applied to an alphabet of 80 ASCII characters printed at ten point and digitized at 300 pixels/inch. This self-correcting method complements, and does not hinder, other methods for improving OCR accuracy, such as linguistic contextual analysis.
Fibrin induces release of von Willebrand factor from endothelial cells. (1987)

Addition of fibrinogen to human umbilical vein endothelial cells in culture resulted in release of von Willebrand factor (vWf) from Weibel-Palade bodies that was temporally related to formation of fibrin in the medium. Whereas no release occurred before gelation, the formation of fibrin was associated with disappearance of Weibel-Palade bodies and development of extracellular patches of immunofluorescence typical of vWf release. Release also occurred within 10 min of exposure to preformed fibrin but did not occur after exposure to washed red cells, clot liquor, or structurally different fibrin prepared with reptilase. Metabolically labeled vWf was immunopurified from the medium after release by fibrin and shown to consist of highly processed protein lacking pro-vWf subunits. The contribution of residual thrombin to release stimulated by fibrin was minimized by preparing fibrin clots with nonstimulatory concentrations of thrombin and by inhibiting residual thrombin with hirudin or heating. We conclude that fibrin formed at sites of vessel injury may function as a physiologic secretagogue for endothelial cells causing rapid release of stored vWf.
Elementary Aspects for Circuit Implementation of Reconfigurable Nanowire Transistors (2014)

A feasibility and performance study of electrically reconfigurable nanowire transistors with selectable pFET and nFET operations is presented. The challenges toward circuit implementation are evaluated based on transient simulations of logic circuits. A novel physical structure capable of computing a NAND as well as NOR function is introduced. The new approach provides a flexible platform to develop and test fine-grain reconfigurable circuits and systems.
GPS radio occultation with CHAMP and GRACE: A first look at a new and promising satellite configuration for global atmospheric sounding (2005)

Abstract. CHAMP (CHAllenging Minisatellite Payload) and GRACE (Gravity Recovery And Climate Experiment) formed a satellite configuration for precise atmospheric sounding during the first activation of the GPS (Global Positioning System) radio occultation experiment aboard GRACE on 28 and 29 July 2004. 338 occultations were recorded aboard both satellites, providing globally distributed vertical profiles of refractivity, temperature and specific humidity. The combined set of CHAMP and GRACE profiles shows excellent agreement with meteorological analysis. Almost no refractivity bias is observed between 5 and 30km, the standard deviation is between 1 and 2% within this altitude interval. The GRACE satellite clock stability is significantly improved in comparison with CHAMP. This allows for the application of a zero difference technique for precise analysis of the GRACE occultation data.
Microwave regenerative frequency dividers with low phase noise (1999)

We demonstrate regenerative divide-by-two (halver) circuits with very low phase modulation (PM) noise at input frequencies of 18.4 GHz and 39.8 GHz. The PM noise of the 18.4 to 9.2 GHz divider pair was L(10 Hz)=-134 dB below the carrier in a 1 Hz bandwidth (dBc/Hz) and L(10 MHz)=-166 dBc/Hz, and the PM noise of the 39.8 GHz to 19.9 GHz divider pair was L(10 Hz)=-122 dBc/Hz and L(10 MHz)=-167 dBc/Hz.
Vulgarisin A, a New Diterpenoid with a Rare 5/6/4/5 Ring Skeleton from the Chinese Medicinal Plant <i>Prunella vulgaris</i> (2014)

Vulgarisin A (1), a new diterpenoid with an unprecedented 5/6/4/5 fused tetracyclic ring skeleton, has been isolated from the medicinal plant Prunella vulgaris Linn. Its structure was characterized by extensive spectroscopic methods, and the absolute configuration was secured by single crystal X-ray diffraction analysis. Compound 1 showed weak cytotoxicity against human lung carcinoma A549 cells with an IC50 value of 57.0 μM.
Five-way Smoking Status Classification Using Text Hot-Spot Identification and Error-correcting Output Codes (2007)

We participated in the i2b2 smoking status classification challenge task. The purpose of this task was to evaluate the ability of systems to automatically identify patient smoking status from discharge summaries. Our submission included several techniques that we compared and studied, including hot-spot identification, zero-vector filtering, inverse class frequency weighting, error-correcting output codes, and post-processing rules. We evaluated our approaches using the same methods as the i2b2 task organizers, using micro- and macro-averaged F1 as the primary performance metric. Our best performing system achieved a micro-F1 of 0.9000 on the test collection, equivalent to the best performing system submitted to the i2b2 challenge. Hot-spot identification, zero-vector filtering, classifier weighting, and error correcting output coding contributed additively to increased performance, with hot-spot identification having by far the largest positive effect. High performance on automatic identification of patient smoking status from discharge summaries is achievable with the efficient and straightforward machine learning techniques studied here.
AN INTER-DISCIPLINARY LANGUAGE FOR INTER-DISCIPLINARY COMMUNICATION: ACADEMIC GLOBALIZATION, ETHOS, PATHOS, AND LOGOS (2014)

Inspired by the intersection of character, emotions, and logic, much like a Hungarian Rhapsody which is beautifully sad; this paper explores ethos, pathos, and logos in the context of Academic Globalization. As students of the world, an inter-disciplinary language is pivotal for inter-disciplinary communication. Given that the current state of the world stems primarily from miscommunications, it is imperative to launch a cognitive language tool which underscores global commonalities and mitigates cultural differences. Such a platform would foster interdisciplinary research, education, and communication. New paradigms would evolve, grounded in ethos, pathos, and logos. Like yin and yang, these states are interrelated, interacting, and interchanging learning spheres. Just as day and night blend at some point; just as the Parthenon epitomized Greek thought, celebrated the birthplace of democracy, and for the first time, depicted everyday citizens in friezes- underscoring their impactful role- ethos, pathos, and logos represent cross-disciplinary communication devices which synergistically transform and ignite academic globalization. The Literature Review links the concepts of ethos, pathos, and logos with the seminal work Lewis and his LMR framework, which has given birth to Cultureactive and subsequently to ICE [InterCultural Edge].
Partial light field tomographic reconstruction from a fixed-camera focal stack (2015)

This paper describes a novel approach to partially reconstruct high-resolution 4D light fields from a stack of differently focused photographs taken with a fixed camera. First, a focus map is calculated from this stack using a simple approach combining gradient detection and region expansion with graph-cut. Then, this focus map is converted into a depth map thanks to the calibration of the camera. We proceed after this with the tomographic reconstruction of the epipolar images by back-projecting the focused regions of the scene only. We call it masked back-projection. The angles of back-projection are calculated from the depth map. Thanks to the high angular resolution we achieve by suitably exploiting the image content captured over a large interval of focus distances, we are able to render puzzling perspective shifts although the original photographs were taken from a single fixed camera at a fixed position.
Can Results Obtained with Commercially Available MicroScan Microdilution Panels Serve as an Indicator of β-Lactamase Production among <i>Escherichia coli</i> and <i>Klebsiella</i> Isolates with Hidden Resistance to ExpandedSpectrum Cephalosporins and Aztreonam? (1998)

Among clinical isolates of Escherichia coli, Klebsiella pneumoniae, and Klebsiella oxytoca, there is an ever-increasing prevalence of beta-lactamases that may confer resistance to newer beta-lactam antibiotics that is not detectable by conventional procedures. Therefore, 75 isolates of these species producing well-characterized beta-lactamases were studied using two MicroScan conventional microdilution panels, Gram Negative Urine MIC 7 (NU7) and Gram Negative MIC Plus 2 (N+2), to determine if results could be utilized to provide an accurate indication of beta-lactamase production in the absence of frank resistance to expanded-spectrum cephalosporins and aztreonam. The enzymes studied included Bush groups 1 (AmpC), 2b (TEM-1, TEM-2, and SHV-1), 2be (extended spectrum beta-lactamases [ESBLs] and K1), and 2br, alone and in various combinations. In tests with E. coli and K. pneumoniae and the NU7 panel, cefpodoxime MICs of >/=2 microg/ml were obtained only for isolates producing ESBLs or AmpC beta-lactamases. Cefoxitin MICs of >16 microg/ml were obtained for all strains producing AmpC beta-lactamase and only 1 of 33 strains producing ESBLs. For the N+2 panel, ceftazidime MICs of >/=4 microg/ml correctly identified 90% of ESBL producers and 100% of AmpC producers among isolates of E. coli and K. pneumoniae. Cefotetan MICs of >/= 8 microg/ml were obtained for seven of eight producers of AmpC beta-lactamase and no ESBL producers. For tests performed with either panel and isolates of K. oxytoca, MICs of ceftazidime, cefotaxime, and ceftizoxime were elevated for strains producing ESBLs, while ceftriaxone and aztreonam MICs separated low-level K1 from high-level K1 producers within this species. These results suggest that microdilution panels can be used by clinical laboratories as an indicator of certain beta-lactamases that may produce hidden but clinically significant resistance among isolates of E. coli, K. pneumoniae, and K. oxytoca. Although it may not always be possible to differentiate between strains that produce ESBLs and those that produce AmpC, this differentiation is not critical since therapeutic options for patients infected with such organisms are similarly limited.
Fluid Flow and Heat Transfer in a Double-pipe Heat Exchanger with Al Foam Filled in the Inner Pipe (2010)

Fluid flow and heat transfer in a double-pipe heat exchanger with Al foams filled in the inner pipe was studied by experiments and numerical simulations.Pressure,velocity and temperature fields of hot air flowing through the inner pipe were investigated and compared with those in a conventional double-pipe heat exchanger.Results show that numerical simulations are consistent with the experiments.Both pressure drop and heat transfer rate increase with increasing the flow rate or the pore density.The filled Al foam enhances the heat transfer greatly but also raises the pressure drop.Comprehensively considering pressure drop and the performance of heat transfer,the heat exchanger filled with the Al foam is much better than that without any foam.
Human Brain Malformations and Their Lessons for Neuronal Migration (2001)

The developmental steps required to build a brain have been recognized as a distinctive sequence since the turn of the twentieth century. As marking tools for experimental embryology emerged, the cellular events of cortical histogenesis have been intensively scrutinized. On this rich backdrop, molecular genetics provides the opportunity to play out the molecular programs that orchestrate these cellular events. Genetic studies of human brain malformation have proven a surprising source for finding the molecules that regulate CNS neuronal migration. These studies also serve to relate the significance of genes first identified in murine species to the more complex human brain. The known genetic repertoire that is special to neuronal migration in brain has rapidly expanded over the past five years, making this an appropriate time to take stock of the emerging picture. We do this from the perspective of human brain malformation syndromes, noting both what is now known of their genetic bases and what remains to be discovered.
Encapsulated MEMS resonators &#x2014; A technology path for MEMS into Frequency Control applications (2010)

MEMS resonators have been discussed as replacements for quartz crystals in electronics timing applications for more than 40 years. The emergence of high-quality, low-cost packaging for MEMS resonators has enabled the first demonstrations of long-term stability and opened the door for commercial applications.
A NUTRITIOUS COCKTAIL FOR THE TREATMENT OF MELANOMA : A CASE REPORT (1998)

The patient is a fifty-one-year-old white male, engineer who has suffered from melanoma in his cervical area for three years. He underwent surgery and it returned; was operated on once more, and his lymphatic net was taken out. He then began taking synthetic interferon in order to avoid new metastases. However, a new nodule appeared in his left lung six months later. He was given a tomography with dirigible nodule puncture, and the tissue sample confirmed melanoma nodule metastasis after histological analysis. His oncologist told him to stop taking synthetic interferon, to go back home and wait for any resolution, saying to him that there was nothing to be done. He was very ill, very thin, desperate and frustrated when he told his son to make an appointment with our office. He started attending our institute in August, 1997. We began his treatment and he quickly improved in regard to his physical performance, sleeping appetite and weight. He took all nutrients methodically (at a rate of 50 capsules daily) and took care of his eating habits, staying away from fried food, fat, sugar, meat, industrialized food and increasing his consumption of natural seeds, vegetables, fruit juices, extra virgin olive oil and a lot of fish and occasionally, chicken. He attended the institute daily to have his intravenous nutrients for five weeks. He
BAI, a novel Cdk inhibitor, enhances farnesyltransferase inhibitor LB42708-mediated apoptosis in renal carcinoma cells through the downregulation of Bcl-2 and c-FLIP (L) (2014)

Previously, we reported the potential of a novel Cdk inhibitor, 2-[1,1'-biphenyl]-4-yl-N-[5-(1,1-dioxo-1λ6-isothiazolidin-2-yl)-1H-indazol-3-yl]acetamide (BAI) as a cancer chemotherapeutic agent. In this study, we investigated mechanisms by which BAI modulates FTI-mediated apoptosis in human renal carcinoma Caki cells. BAI synergizes with FTI to activate DEVDase, cleavage of poly ADP-ribose polymerase (PARP), and degradation of various anti-apoptotic proteins in Caki cells. BAI plus LB42708-induced apoptosis was inhibited by pretreatment with pan-caspase inhibitor, z-VAD-fmk, but not by overexpression of CrmA. The ROS scavenger, N-acetylcysteine (NAC) did not reduce BAI plus LB4270-induced apoptosis. Co-treatment of BAI and LB42708 reduced the mitochondrial membrane potential (MMP, ∆Ψm) in a time-dependent manner, and induced release of AIF and cytochrome c from mitochondria in Caki cells. Furthermore, BAL plus LB42708 induced downregulation of anti-apoptotic proteins [c-FLIP (L), c-FLIP (s), Bcl-2, XIAP, and Mcl-1 (L)]. Especially, we found that BAI plus LB42708-induced apoptosis was significantly attenuated by overexpression of Bcl-2 and partially blocked by overexpression of c-FLIP (L). Taken together, our results show that the activity of BAI plus LB42708 modulate multiple components in apoptotic response of human renal Caki cells, and indicate a potential as combinational therapeutic agents for preventing cancer such as renal carcinoma.
Non-Volatile Neuromorphic Computing based on Logic-Compatible Embedded Flash Memory Technology (2020)

University of Minnesota Ph.D. dissertation. 2020. Major: Electrical Engineering. Advisor: Chris Kim. 1 computer file (PDF); xxi, 130 pages.
Comparative in vitro activity of sulfametrole/trimethoprim and sulfamethoxazole/trimethoprim and other agents against multiresistant Gram-negative bacteria (2013)

Antifolate combinations remain the most active antimicrobials against less common non-fermenters, importantly including S. maltophilia and Burkholderia spp., but resistance is prevalent among ESBL- and carbapenemase-producing Enterobacteriaceae. Sulfametrole/trimethoprim had similar activity to sulfamethoxazole/trimethoprim against non-fermenters.
An ultra-low-power, radiation-tolerant Reed Solomon encoder for space applications (2004)

Power is a limiting constraint in spacecraft design. This paper describes a Reed Solomon encoder designed for NASA using a triple metal, 0.35 /spl mu/m, ultra-low-power (500mV) CMOS process. Comparisons with a 3.3 V version show a 29.6 to 1 reduction in power to 14.3 mW at 60 MHz. Hardness against space radiation effects was achieved through circuit and layout techniques.
Bcl-x<sub>L</sub>can inhibit apoptosis in cells that have undergone Fas-induced protease activation (1997)

Programmed cell death or apoptosis provides an irreversible mechanism for the elimination of excess or damaged cells. Several recent studies have implicated the activation of the interleukin 1beta-converting enzyme/Ced-3 (ICE/Ced-3) family of proteases as the "point of no return" in apoptotic cell death, while others have suggested that loss of mitochondrial membrane potential (delta psi(m)) is the ultimate determinant of cell death. The temporal relationship of these two events during apoptosis and the role of Bcl-2 proteins in inhibiting these steps has not been defined. To examine these issues, control and Bcl-x(L)-transfected Jurkat T cells were treated with Fas antibodies in the presence and absence of the ICE protease inhibitor zVAD-FMK. ICE/Ced-3 protease activity was monitored by following the cleavage of poly(ADP-ribose) polymerase (PARP) and delta psi(m) was followed by rhodamine 123 fluorescence. Although Bcl-x(L) expression did not block Fas-induced protease activation, it substantially inhibited the subsequent loss of delta psi(m) and cell death in Fas-treated cells. In contrast, zVAD-FMK blocked PARP cleavage as well as loss of delta psi(m) and cell death. Together these data demonstrate that Bcl-x(L) can maintain cell viability by preventing the loss of mitochondrial membrane potential that occurs as a consequence of ICE/Ced-3 protease activation.
Analysis of resource sharing in information providing services (2002)

The key to an economical service is in the sharing of physical resources among the customers. This applies to the information storage and sourcing devices, as well as to the transmission bandwidth. One of the possible solutions to the resource sharing problem is the grouping of customers with similar service requests, and broadcasting the information rather than granting the service individually. The customers' behavior (in particular, the customers' patience) is modeled, and the service performance for different service scenarios is analyzed. It is shown that in case of the threshold-activated service scenario, it is possible to optimize the service performance by using the statistics of the service requests and customer patience.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Calibration-free quantification of absolute oxygen saturation based on the dynamics of photoacoustic signals (2013)

Photoacoustic tomography (PAT) is a hybrid imaging technique that has broad preclinical and clinical applications. Based on the photoacoustic effect, PAT directly measures specific optical absorption, which is the product of the tissue-intrinsic optical absorption coefficient and the local optical fluence. Therefore, quantitative PAT, such as absolute oxygen saturation (sO₂) quantification, requires knowledge of the local optical fluence, which can only be estimated through invasive measurements or sophisticated modeling of light transportation. In this Letter, we circumvent this requirement by taking advantage of the dynamics in sO₂. The new method works when the sO₂ transition can be simultaneously monitored with multiple wavelengths. For each wavelength, the ratio of photoacoustic amplitudes measured at different sO₂ states is utilized. Using the ratio cancels the contribution from optical fluence and allows calibration-free quantification of absolute sO₂. The new method was validated through both phantom and in vivo experiments.
Fiber link loss monitoring scheme in bidirectional WDM transmission using ASE-injected FP-LD (2006)

We propose and demonstrate a novel fiber link loss monitoring method for a wavelength-division-multiplexed (WDM) passive optical network. This method is based on the optical signal comparison between a reference amplified spontaneous emission signal and its reflection from an optical reflector. Therefore, we can calculate the link loss exactly and also measure the characteristics of upstream optical signals without suspending the in-service channels. Since this scheme does not use narrow-band wavelength-dependent components such as fiber Bragg gratings, it is cost-effective in implementation and maintenance within a real optical network. We experimentally demonstrate that the link quality of upstream signals as well as fiber link faults on all WDM channels can be monitored in real time.