gebhart/patrepeval huggingface dataset:
Different Regulation of Growth Hormone-Releasing Factor-Sensitive Adenylate Cyclase in the Anterior Pituitary of Young and Aged Rats* (1987)

Low basal GH secretion and reduced GH responsiveness to different GH secretagogues, including GHRF, have been reported in aged animals and humans. Parallel to the in vivo findings, an impaired GH responsiveness to GHRF is evident in somatotropes from old rats of either sex. We report here that in anterior pituitaries (APs) from aged male and female rats GHRF-induced stimulation of adenylate cyclase (AC) activity was strikingly reduced (male rats, change from baseline 700% in young and 100% in old rats) or lacking (female rats, change from baseline 430% in young and 13% in old rats) when compared to that evoked by GHRF in the APs from young counterparts. Pretreatment with GHRH (5 micrograms/rat iv for 3 days) decreased the high basal AC activity of old male rats [from 33.38 +/- 3.60 to 15.99 +/- 5.75 (SEM) pmol cAMP/min.mg protein], did not alter the GHRF-stimulated rise in AC activity in old male rats, and induced a small but unequivocal rise in AC activity in old female rats (change from baseline 35% vs. 13%, respectively). Pretreatment with GHRF markedly reduced the acute effect of GHRF in the APs from young rats of both sexes (male rats, change from baseline 360% and 700%; female rats, change from baseline 230% and 430% in GHRF-pretreated and control rats, respectively). In parallel studies performed in female rats, it was shown that in vivo pretreatment with GHRF at the same schedule markedly reduced the effect of acute GHRF stimulation on GH secretion from cultured pituitary cells of young rats but left unchanged GHRF-induced stimulation of GH secretion from pituitary cells of old rats. In all, these data suggest that deficiency of endogenous GHRF synthesis and/or release may underlie defective GH secretion in old rats and that a GHRF replacement regimen that reduces the sensitivity of the young somatotrope cells does not alter the sensitivity of (male rats) or exerts a priming effect (female rats) on the old somatotrope cell.
A Human-Derived Reporter Gene for Noninvasive Imaging in Humans: Mitochondrial Thymidine Kinase Type 2 (2007)

We have tested a human-derived reporter gene that is likely to be nonimmunogenic and potentially allows for long-term monitoring of different molecular-genetic processes by nuclear imaging techniques in humans. Using (124)I-FIAU, (18)F-FIAU, or (18)F-FEAU, it should be possible to image DeltahTK2 reporter gene expression with PET in preclinical and clinical studies.
Microfluidic Mixing via Acoustically Driven Chaotic Advection (2008)

Mixing presents a notoriously difficult problem in small amounts of fluids. Herein, surface acoustic waves provide a convenient technique to generate time-dependent flow patterns. These flow patterns can be optimized in such a way that advected particles are mixed most efficiently in the fluid within a short time compared to the time pure diffusion would take. Investigations are presented for the mixing efficiency of a flat cylinder that is driven by two surface acoustic waves. The experimental results favorably agree with model calculations of the flow patterns and the advective transport.
Human motion retrieval based on deep learning and dynamic time warping (2017)

A novel motion retrieval approach based on statistical learning and Bayesian fusion is presented. The approach includes two primary stages. (1) In the learning stage, fuzzy clustering is utilized firstly to get the representative frames of motions, and the gesture features of the motions are extracted to build a motion feature database. Based on the motion feature database and statistical learning, the possibility distribution functions of different motion classes are obtained. (2) In the motion retrieval stage, the query motion feature is extracted firstly according to stage (1). Similarity measurements are then conducted employing a novel method that combines category-based motion similarity distances with similarity distances based on canonical correlation analysis. The two motion distances are fused using Bayesian estimation, and the retrieval results are ranked according to the fused values. The effectiveness of the proposed method is verified experimentally.
Reactions of Rare Earth Hydrated Nitrates and Oxides with Formamide: Relevant to Recycling Rare Earth Metals (2015)

Reactions of hydrated rare earth nitrates with formamide under mild solvothermal reaction conditions give three different rare earth formate structure types Ln(HCOO)3, Ln(HCOO)3·(HCONH2)2, and [CH(NH2)2][Ln(HCOO)4]. The conditions for the formation of a specific structure type were determined as a function of the size of the rare earth cation, the reaction time, and the reaction temperature. Thirteen previously unreported rare earth formates were obtained; nine were isostructural compounds with the composition Ln(HCOO)3·(HCONH2)2 (denoted by LnFA, Ln = Y (1Y), Sm (2Sm), Eu (3Eu), Gd (4Gd), Tb (5Tb), Ho (6Ho), Tm (7Tm), Yb (8Yb), and Lu (9Lu)), and four were isostructural compounds with the composition [CH(NH2)2][Ln(HCOO)4] (denoted by LnFMD, Ln = Sm (10Sm), Ho (11Ho), Tm (12Tm), and Lu (13Lu)). All compounds contain metal ions that are eight coordinated by oxygen atoms and are connected by anti–anti bridging formato ligands to form frameworks. The coordination geometry is bisdisphenoid in LnFA and square antiprismatic in LnFMD. In contrast, the larger rare earth ions that adopt the Ln(HCOO)3 structure are nine coordinated by oxygen atoms in tricapped trigonal prismatic coordination geometry. The luminescence properties of 2Sm, 3Eu, 5Tb, and 10Sm were investigated by solid state photoluminescence spectroscopy in the range of 300–800 nm. Rare earth oxides were also found to react directly with formamide in the presence of a small amount of water to give the same compositions suggesting that the reaction chemistry can provide a basis for a process to recover rare earth metals from end-of-life products containing oxides such as the phosphors used in fluorescent light bulbs. This possibility was demonstrated by crystallizing rare earth formates starting with a commercially available trichromatic phosphor.
Transparent hybrid polymer stamp copies with sub-50-nm resolution for thermal and UV-nanoimprint lithography (2009)

The organic-inorganic hybrid polymer Ormostamp was successfully used for the fabrication of inexpensive, transparent working stamps to be used in nanoimprint lithography. The stamps were produced from different masters by casting and UV exposure of a viscous precursor. The cured hybrid stamp with the replicated surface relief was imprinted into several thermoplastic materials with up to 180 °C imprint temperature. In this article the authors show the effect of the imprint temperature on the structural fidelity. By using combined thermal and UV-nanoimprint lithography at 110 °C imprint temperature, a resolution down to 35 nm is demonstrated. They also investigated deterioration effects due to plasma treatment to simulate the effect of multiple recoating steps.
A weighted similarity measure approach to predict intensive care unit transfers (2017)

Classification models have proven useful for predicting clinical interventions and patient outcomes. One of the key issues that affect the predictive ability of supervised learning frameworks in the healthcare scenario is imbalance in data sets. In addition, non-uniform data collection processes in clinical scenarios lead to poor quality data sets. We designed a novel approach to predict Intensive Care Unit (ICU) transfers based on a weighted-similarity measure for patients outside of ICUs. The approach uses similarity between patient vital signs as input features for training the model. To address the data quality issues, we demonstrate the use of various up-sampling and down-sampling techniques to handle imbalanced data sets and train a classifier on a re-sampled data set. The data set used for testing the approach is derived from the MIMIC III database. We compare our results with the clinically accepted methodology to capture patient's health state, assisting in clinical decision making. Our model outperforms the standard methodology used in clinical decision making in standard scoring metrics such as F1-score, False Positive Rate and Mathew's Correlation Coefficient [MCC].
Analysis of Rotator Cuff Repair Trends in a Large Private Insurance Population (2013)

IV, cross-sectional study.
Nanophotonic cavity optomechanics with propagating acoustic waves at frequencies up to 12  GHz (2015)

Strong coherent interactions between colocalized optical and mechanical eigenmodes of various cavity optomechanical systems have been explored intensively toward quantum information processing using both photons and phonons. In contrast to localized modes, propagating mechanical waves are another form of phonons that can be guided and manipulated like photons in engineered phononic structures. Here, we demonstrate sideband-resolved coupling between multiple photonic nanocavities and propagating surface acoustic waves up to 12 GHz. Coherent and strong photon–phonon interaction is manifested with electro-optomechanically induced transparency, absorption, and amplification, and phase-coherent interaction in multiple cavities. Inside an echo chamber, it is shown that a phonon pulse can interact with an embedded nanocavity for multiple times. Our device provides a scalable platform to optomechanically couple phonons and photons for microwave photonics and quantum photonics.
Secure Lossy Transmission over Wiretap Channels with Side Information and State Information (2021)

This paper investigates the problem of secure lossy transmission over wiretap channels with side information and state information. Aiming at the reliability and security of compressed pictures, videos and other files when they are transmitted, a wiretap channel model with side information and state information and a secure lossy source transmission scheme based on double binning technique under this model are proposed. By using Fano inequality and Csiszar sum identity, the inner bounds of transmission rate, distortion rate and information leakage rate are proved. Considering noisy situations in reality, the Gaussian noise channel under this model is analyzed concretely as an example. Based on error estimation and differential entropy theorem, the inner bounds of transmission rate and distortion rate are obtained. Moreover, the equivocation rate is introduced to transform the information leakage rate into the minimum mean square error of the estimated source and its outer bound is also obtained. The simulation results show that under the optimal conditions of the proposed system model, the transmission rate can reach 0.7315 bits/source bit, the distortion rate can reach 0.0052 bits/source bit and the information leakage rate can reach 0.1286 bits/source bit.
A modal perspective of lung response (1978)

The qualitative modal structure of lung response is investigated. Asymmetry of the branching airway network of the lung leads to clumping of system eigenvalues into distinct and well-separated clusters at low frequency. The breadth of the eigenvalue clusters increases with the degree of asymmetry and frequency. At high frequency the breadth of the clusters exceeds the cluster spacing so that distinct eigenvalue clusters are no longer observed. Symmetric airway networks lead to degenerate mode clusters with large eigenvalue redundancy. The average density of eigenvalues of the undamped system is estimated to be higher than 0.5 per Hz. All modes appear to be in modal overlap.
A Monolithic Digital Ripple-Based Adaptive-Off-Time DC-DC Converter With a Digital Inductor Current Sensor (2014)

A ripple-based digital controller requires inductor current ripple as feedback signals and analog RC inductor current sensors can be used for sensing the ripple. However, the passive RC components are bulky to integrate on-chip and the digital controller cannot use the analog ripple for the control purpose unless extra ADCs are available to quantize the signal. Therefore, a digital inductor current sensor is presented in this paper for obtaining the ripple in the digital domain. As compared to the existing designs, the digital inductor current sensor does not require extra ADCs or knowledge of the inductor DCR. A ripple-based digital controller is designed to demonstrate how the digital sensor can be utilized. A digital frequency-lock-loop is also incorporated into the digital controller to alleviate the problem of variable switching-frequency that is commonly found in the ripple-based control scheme. Both the digital sensor and controller are fabricated in UMC 0.13 μm digital CMOS process with a small chip area of 220 μm×220 μm. Measurements results show that a 2 MHz (max. ±6.5% in variation) buck converter achieves load-transient responses of about 5 μs by using the digital controller. The peak efficiency is 91% at a nominal load current of 100 mA.
Options for Energy from Algae at Wastewater Treatment Facilities (2011)

Options for Energy from Algae at Wastewater Treatment FacilitiesThe development of algae biofuels is a priority for the U.S. Department of Energy, Department of Defense, and many other organizations. Large-scale algae production facilities are already in the planning stage. Algal biomass harvested from wastewater treatment ponds can also potentially be used as a feedstock for renewable fuels such as biogas, biodiesel, bio-oil or synthesis gas. Despite the...Author(s)Matt HuttonRuth SpierlingDan HeimelIan WoertzTryg LundquistSourceProceedings of the Water Environment FederationSubjectSession 113: Algae for Treatment and BiofuelsDocument typeConference PaperPublisherWater Environment FederationPrint publication date Jan, 2011ISSN1938-6478SICI1938-6478(20110101)2011:7L.7283;1-DOI10.2175/193864711802793669Volume / Issue2011 / 7Content sourceWEFTECFirst / last page(s)7283 - 7293Copyright2011Word count259Subject keywordsAlgaebiofuelanaerobic digestionbiodieselwastewater treatment
A modified Smith predictor for controlling a process with an integrator and long dead-time (1996)

A modification of the Smith predictor for controlling higher-order processes with integral action and long dead-time is proposed. The controller has a quite simple structure which is obtained based on the model consisting of an ideal integrator and dead-time and which includes only three tuning parameters: the dead-time, velocity gain of the model, and the desired time constant of the first-order closed-loop setpoint response. By adjusting these three parameters, high performance can be obtained both for the setpoint response and for the load disturbance rejection.
Entrepreneurship and Networking in the Trafficking of Sex Workers from East to West Europe. Cases from Belgium (2002-2008) (2011)

Which profiles of entrepreneurship and networking can we distinguish in Belgium (and probably by extension its neighbouring countries as well) among sex workers, who have entered from Eastern Europe into Western Europe, and who are the victims of trafficking, and among others who are the active agents? Our central contention is that earning big money is the central catalyst in criminal entrepreneurship. This entrepreneurship however, takes place within a framework where agreements cannot be judicially enforced nor a constant supply of money can be guaranteed. While lacking juridical tools, one needs agreements that guarantee a sufficient degree of mutual trust. Entrepreneurs do not like to run too high a risk unnecessarily. Ideally, there could be positive social capital (Woolcock, 2001) between the actors on the field, as there is between colleagues in a workplace. This concerns the modalities along which the sex workers are recruited and thereafter exploited as well as their financial ʽmodus operandiʼ. This trust should continue to exist even when the market conditions suddenly change. In this context of entrepreneurship we see a network as a set of junctions of persons and/or organisations, complemented by variously qualified relations between these junctions (Williams, 1998; Von Lampe, 2002; McIllwain, 1999). The actors are working in flexible connections (Fijnaut, 1996) based on reciprocal dependency. Some people inside the networks e.g. financiers or organisers play a central role. These individuals are the important ʽjunctionsʼ in and between criminal networks (Kleemans, 2002). This paper tries to elucidate what we have learned about entrepreneurship and networking among sex workers in Belgium (particularly in and around the area of Brussels North station prostitution district around the ʽRue dʼAerschotʼ). We studied 25 juridical files, analysing them from an entrepreneurship and networking point of view and will offer our findings.
DISCOVERING AND EXPERIENCING THE FUNDAMENTAL THEOREM OF CALCULUS (1992)

ABSTRACT This paper is intended to offer calculus students and teachers the opportunity to motivate and discover the (first) Fundamental Theorem of Calculus in an experimental, experiential, inductive, intuitive, vernacular-based manner. Starting from the observation that a distance travelled at a constant speed corresponds to the area inside a rectangle, a precursor of the FTC is quickly and painlessly motivated and discovered. Its validity is then investigated both experimentally and theoretically. Once its plausibility is established, pictures and words are wedded to generalize this discovery to a standard statement of the fundamental theorem.
A system for remote meter reading and load management (1999)

The systems for remote meter reading and load management which have been, for evaluation purposes, installed in New Belgrade and Pancevo are described in this paper. Two way communication link between the center and all the meters is established via power distribution lines by means of a modulated high frequency signal subjected to an additional direct sequence spread spectrum processing. In this way an improved signal to noise ratio is achieved which stretches the propagation distance at a low level injected signal amplitude required by CENELEC standards. The whole city area is supposed to be divided into numerous zones consisting of several MV/LV substation areas capacitively bridged in adjacent points for HF signal transmission. All zones are connected via leased telephone lines to the dispatching center from which messages can be transmitted to and data received from a zonal concentration center. A peripheral unit is designed which not only collects data from up to 48 meters and affects transmission upon request, but also performs basic data processing such as current power engagement, aggregate power recording, tariffs management, etc. By regular data gathering from modems an intelligent tariff management with daily as well as seasonal adjustment can be implemented. On the bases of the energy and power flow monitoring, possible losses can be investigated, and better insight into the loading, as a planning parameter, can be obtained.
Starling-Like Flow Control of a Left Ventricular Assist Device: In Vitro Validation (2013)

Abstract The application of rotary left ventricular (LV) assist devices (LVADs) is expanding from bridge to transplant, to destination and bridge to recovery therapy. Conventional constant speed LVAD controllers do not regulate flow according to preload, and can cause over/underpumping, leading to harmful ventricular suction or pulmonary edema, respectively. We implemented a novel adaptive controller which maintains a linear relationship between mean flow and flow pulsatility to imitate native Starling-like flow regulation which requires only the measurement of VAD flow. In vitro controller evaluation was conducted and the flow sensitivity was compared during simulations of postural change, pulmonary hypertension, and the transition from sleep to wake. The Starling-like controller's flow sensitivity to preload was measured as 0.39 L/min/mm Hg, 10 times greater than constant speed control (0.04 L/min/mm Hg). Constant speed control induced LV suction after sudden simulated pulmonary hypertension, whereas Starling-like control reduced mean flow from 4.14 to 3.58 L/min, maintaining safe support. From simulated sleep to wake, Starling-like control increased flow 2.93 to 4.11 L/min as a response to the increased residual LV pulsatility. The proposed controller has the potential to better match device outflow to patient demand in comparison with conventional constant speed control.
Biosynthesis of amino acids. Investigation of the mechanism of .beta.-tyrosine formation (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBiosynthesis of amino acids. Investigation of the mechanism of .beta.-tyrosine formationRonald J. Parry and Z. Kurylo-BorowskaCite this: J. Am. Chem. Soc. 1980, 102, 2, 836–837Publication Date (Print):January 1, 1980Publication History Published online1 May 2002Published inissue 1 January 1980https://pubs.acs.org/doi/10.1021/ja00522a065https://doi.org/10.1021/ja00522a065research-articleACS PublicationsRequest reuse permissionsArticle Views194Altmetric-Citations33LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Synthesis of a Molecularly Imprinted Polymer on Silica-Gel Surfaces for the Selective Adsorption of Indole from Fuel Oil (2013)

We report a successful synthesis of a molecularly imprinted polymer (MIP) by surface imprinting technique. The polymer was then used for selective adsorption of indole from fuel oil. Nitrogen adsorption, Fourier transform-infrared spectrometry and scanning electron microscopy were used to characterize the morphology of indole–MIP. The study results show that indole–MIP has a large specific surface area and enhanced porosity. Static adsorption data indicate that the adsorption capacity of indole–MIP is 54.6639 mg g −1 , with the adsorption equilibrium achieved in 40 minutes. The indole–MIP molecule has a high adsorption and elution rate due to the presence of hydrogen bond between the functional monomer (4-vinylpyridine) and the template molecule (indole). According to the results of thermodynamic analysis, the adsorption process is spontaneous. In addition, based on the results of kinetics and isotherm analysis, adsorption performances obey pseudo-second-order model and Langmuir equation. The selectivity of indole–MIP is favourable and can be reused even after 10 cycles.