gebhart/patrepeval huggingface dataset:
Terminator Tape: A Cost-Effective De-Orbit Module for End-of-Life Disposal of LEO Satellites (2009)

The rapid growth of the orbital debris population poses an increasing threat to military, commercial, and civilian science spacecraft in Earth orbit. NASA, the DoD, ESA, and other organizations have begun to respond to this problem by imposing requirements for debris mitigation upon new space systems. These requirements specify that spacecraft at end-oflife be disposed of by either atmospheric re-entry within 25 years, maneuver to a higher storage orbit, or direct retrieval. For most satellites operating in low Earth orbit (LEO), atmospheric re-entry is the most viable option. To provide a cost-effective means for satellite operators to comply with the 25-year post-mission orbital lifetime restriction, Tethers Unlimited is developing a lightweight de-orbit module called the “Terminator Tape ™ ”. The Terminator Tape is a small module that bolts onto any side of a spacecraft during satellite integration. At the completion of the satellite’s mission, the satellite will activate the Terminator Tape module. The module will then deploy a several-hundred-meter length of thin conducting tape. This tape will not only significantly enhance the aerodynamic drag experienced by the system, but will also generate electrodynamic drag forces through passive interactions with the Earth’s magnetic field and conducting ionospheric plasma, de-orbiting the satellite within 25 years. Two modules are currently in development, one sized for microsatellites operating at altitudes of less than 900 km, and the other sized for CubeSats. In this paper, we will present design overviews and concept of operations for both modules, as well as analyses of deorbit of satellites using these modules.
Toward consistent and productive complex media for industrial fermentations: Studies on yeast extract for a recombinant yeast fermentation process (2003)

Yeast extract (YE) is commonly used as a key component in the complex media for industrial fermentations. However, the lot-to-lot variation of this raw material frequently requires extensive "use testing" of many lots to identify only the few that support desired fermentation performance. Through extensive fermentation studies and chemical analyses, we have identified adenine and two metabolizable carbon sources, trehalose and lactate, as the principle components in YE that affect the production of a recombinant protein antigen by a yeast strain. Adenine is required for culture growth and the relationship between biomass and measured adenine can be expressed by a Michaelis-Menten model, while the slowly metabolized trehalose serves to maintain the energy supply to the continued antigen synthesis. The rapidly utilized lactate exerts an indirect positive effect by sparing some of the accumulated ethanol from being consumed for growth to being utilized in the product formation. The effects of these YE components are mutually dependent. Based on the database generated from 40 lots at laboratory scale, a relatively high level of carbon sources in YE (trehalose plus lactate, >9.5% w/w) and an intermediate level of adenine (0.14-0.24% w/w) appear to be the minimal requirement of a good lot for this recombinant yeast fermentation. Many poor lots were improved in lab fermenters by rational supplementation of trehalose, lactate, or adenine to compensate for their insufficiencies. At the large production scale, predictions based on adenine and trehalose/lactate contents in various YE lots used correlated reasonably well with culture growth and antigen yield, illustrating the feasibility of such a simple chemical/biochemical analysis as a rapid and reliable initial screening tool. Without incurring any compositional change to an established manufacturing medium, this study demonstrates an effective approach to achieve consistency in fermentations employing complex nutrients and to improve fermentation productivities supported by suboptimal lots of raw material.
Parallelizing GF(P) elliptic curve cryptography computations for security and speed (2007)

The elliptic curve cryptography can be observed as two levels of computations, upper scalar multiplication level and lower point operations level. We combine the inherited parallelism in both levels to reduce the delay and improve security against the simple power attack. The best security and speed performance is achieved when parallelizing the computation to eight parallel multiplication operations. This strategy is worth considering since it shows very attractive performance conclusions.
A non-free-space propagation x-ray phase contrast imaging method sensitive to phase effects in two directions simultaneously (2009)

We present an x-ray phase contrast imaging method based on coded apertures sensitive to phase effects in two directions simultaneously. To date, this is the only non-free-space propagation approach with this capability. Whereas the use of free-space propagation methods is limited to synchrotron radiation or microfocal x-ray sources, which impose severe limits in terms of practical applicability, coded-aperture based methods have been shown to provide synchrotronlike phase contrast enhancements with conventional x-ray sources. A two-directional sensitive method working with conventional sources could create a breakthrough in medical imaging, where two-directional sensitivity is often a mandatory requirement.
Spicamycin, a New Differentiation Inducer of Mouse Myeloid Leukemia Cells (Ml) and Human Promyelocytic Leukemia Cells (HL-60) (1985)

Journal Article Spicamycin, a New Differentiation Inducer of Mouse Myeloid Leukemia Cells (Ml) and Human Promyelocytic Leukemia Cells (HL-60) Get access Yoichi Hayakawa, Yoichi Hayakawa Institute of Applied Microbiology, The University of Tokyo, Bunkyo-ku, Tokyo, 113, Japan Search for other works by this author on: Oxford Academic Google Scholar Masaya Nakagawa, Masaya Nakagawa Institute of Applied Microbiology, The University of Tokyo, Bunkyo-ku, Tokyo, 113, Japan Search for other works by this author on: Oxford Academic Google Scholar Hiroyuki Kawai, Hiroyuki Kawai Applied Bioscience Laboratory, Kirin Brewery Co., Ltd., Souja Maebashi, Gunma, 371, Japan Search for other works by this author on: Oxford Academic Google Scholar Kozo Tanabe, Kozo Tanabe Applied Bioscience Laboratory, Kirin Brewery Co., Ltd., Souja Maebashi, Gunma, 371, Japan Search for other works by this author on: Oxford Academic Google Scholar Hiroshi Nakayama, Hiroshi Nakayama Institute of Applied Microbiology, The University of Tokyo, Bunkyo-ku, Tokyo, 113, Japan Search for other works by this author on: Oxford Academic Google Scholar Akira Shimazu, Akira Shimazu Institute of Applied Microbiology, The University of Tokyo, Bunkyo-ku, Tokyo, 113, Japan Search for other works by this author on: Oxford Academic Google Scholar Haruo Seto, Haruo Seto Institute of Applied Microbiology, The University of Tokyo, Bunkyo-ku, Tokyo, 113, Japan Search for other works by this author on: Oxford Academic Google Scholar Noboru Ōtake Noboru Ōtake Institute of Applied Microbiology, The University of Tokyo, Bunkyo-ku, Tokyo, 113, Japan Search for other works by this author on: Oxford Academic Google Scholar Agricultural and Biological Chemistry, Volume 49, Issue 9, 1 September 1985, Pages 2685–2691, https://doi.org/10.1080/00021369.1985.10867129 Published: 01 September 1985 Article history Received: 15 March 1985 Published: 01 September 1985
Enhanced privacy id (2007)

Direct Anonymous Attestation (DAA) is a scheme that enables the remote authentication of a Trusted Platform Module (TPM) while preserving the user's privacy. A TPM can prove to a remote party that it is a valid TPM without revealing its identity and without linkability. In the DAA scheme, a TPM can be revoked only if the DAA private key in the hardware has been extracted and published widely so that verifiers obtain the corrupted private key. If the unlinkability requirement is relaxed, a TPM suspected of being compromised can be revoked even if the private key is not known. However, with the full unlinkability requirement intact, if a TPM has been compromised but its private key has not been distributed to verifiers, the TPM cannot be revoked. Furthermore, a TPM cannot be revoked from the issuer, if the TPM is found to be compromised after the DAA issuing has occurred. In this paper, we present a new DAA scheme called Enhanced Privacy ID (EPID) scheme that addresses the above limitations. While still providing unlinkability, our scheme provides a method to revoke a TPM even if the TPM private key is unknown. This expanded revocation property makes the scheme useful for other applications such as for driver's license. Our EPID scheme is efficient and secure in the same security model as DAA, i.e. in the random oracle model under the strong RSA assumption and the decisional Diffie-Hellman assumption.
A bispecific Tribody PET radioligand for visualization of amyloid-beta protofibrils – a new concept for neuroimaging (2017)

Antibodies are highly specific for their target molecules, but their poor brain penetrance has restricted their use as PET ligands for imaging of targets within the CNS. The aim of this study was to develop an antibody-based radioligand, using the Tribody<sup>TM</sup> format, for PET imaging of soluble amyloid-beta (Aβ) protofibrils, which are suggested to cause neurodegeneration in Alzheimer's disease. Antibodies, even when expressed in smaller engineered formats, are large molecules that do not enter the brain in sufficient amounts for imaging purposes. Hence, their transport across the blood-brain barrier (BBB) needs to be facilitated, for example through interaction with the transferrin receptor (TfR). Thus, a Fab fragment of the TfR antibody 8D3 was fused with two single chain variable fragments (scFv) of the Aβ protofibril selective antibody mAb158. Five Tribody<sup>TM</sup> proteins (A1-A5) were generated with different linkers between the Fab-8D3 and scFv-158. All proteins bound to TfR and Aβ protofibrils in vitro. Three of the proteins (A1-A3) were radiolabeled with iodine-125 and studied ex vivo in wild-type (wt) and transgenic mice overexpressing human Aβ. The systemic pharmacokinetics were similar with half-lives in blood of around 9h for all three ligands. Brain concentrations at 2h were around 1% of the injected dose per gram brain tissue, which is similar to what is observed for small molecular radioligands and at least 10-fold higher than antibodies in general. At 72h, transgenic mice showed higher concentrations of radioactivity in the brain than wt mice (12, 15- and 16-fold for A1, A2 and A3 respectively), except in the cerebellum, an area largely devoid of Aβ pathology. A3 was then labelled with iodine-124 for in vivo positron emission tomography (PET) imaging. Brain concentrations were quantified in six different regions showing a clear distinction both quantitatively and visually between wt and transgenic mice and a good correlation with Aβ pathology. We have thus produced a recombinant, bispecific protein, actively transported into the brain, for PET imaging within the CNS. In a longer perspective, this technique may enable imaging of other proteins involved in neurodegenerative diseases for which imaging agents are completely lacking today.
3D Framework DNA Origami with Layered Crossovers (2016)

Abstract Designer DNA architectures with nanoscale geometric controls provide a programmable molecular toolbox for engineering complex nanodevices. Scaffolded DNA origami has dramatically improved our ability to design and construct DNA nanostructures with finite size and spatial addressability. Here we report a novel design strategy to engineer multilayered wireframe DNA structures by introducing crossover pairs that connect neighboring layers of DNA double helices. These layered crossovers (LX) allow the scaffold or helper strands to travel through different layers and can control the relative orientation of DNA helices in neighboring layers. Using this design strategy, we successfully constructed four versions of two‐layer parallelogram structures with well‐defined interlayer angles, a three‐layer structure with triangular cavities, and a 9‐ and 15‐layer square lattices. This strategy provides a general route to engineer 3D framework DNA nanostructures with controlled cavities and opportunities to design host–guest networks analogs to those produced with metal organic frameworks.
Maximizing the storage capacity of nonvolatile memories (2011)

We propose variable-level cell, a new data representation scheme, for nonvolatile memories (including flash memories, phase-change memories, etc.). We derive its storage capacity, and analyze its performance on rewriting data.
kW all-semiconductor mode-locked extreme chirped pulse amplification (XCPA) system (2005)

We report the demonstration of > kW peak power from an all-semiconductor mode-locked laser extreme chirped pulse amplification(XCPA) system implemented with a chirped fiber Bragg grating as an extreme pulse stretcher/compressor. Also, we investigate the nonlinear behavior in the XCPA system implemented with a single mode fiber pre-stretcher.
Continuous synthesis of artemisinin-derived medicines (2014)

Described is a continuous, divergent synthesis system which is coupled to continuous purification and is capable of producing four anti-malarial APIs. The system is comprised of three linked reaction modules for photooxidation/cyclization, reduction, and derivatization. A fourth module couples the crude reaction stream with continuous purification to yield pure API.
Thirty Two-Stage CMOS TDI Image Sensor With On-Chip Analog Accumulator (2013)

This brief presents a 32-stage CMOS time delay integration image sensor with on-chip column parallel analog accumulator. Temporal oversampling technique is applied in the sensor to realize synchronous signal capturing. A column parallel analog accumulator with layout size of 0.09 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> is integrated at both sides of pixel array. Through adopting input-offset storing technique, a column fixed pattern noise because of the amplifier's offset variations is reduced by the accumulator. The accumulator also acts as a pixel noise canceller. The fabricated chip in 0.18- μm one-poly four-metal 1.8/3.3-V CMOS technology achieves the maximum line rate of 3875 lines/s. The measured signal-to-noise ratio of the fabricated sensor is improved on average by 11.9 dB at 16 stages and 14.2 dB at 32 stages. The presented sensor is suitable for application in low illumination, high scanning speed, and remote sensing systems.
Development of the selective hydrophobic coagulation process (1992)

A novel technique for selectively coagulating and separating coal from dispersed mineral matter has been developed at Virginia Tech. The process, Selective Hydrophobic Coagulation (SHC), has been studied since 1986 under the sponsorship of the US Department of Energy. The SHC process differs from oil agglomeration, shear or polymer flocculation, and electrolytic coagulation processes in that it does not require reagents or additives to induce the formation of coagula. In most cases, simple pH control is all that is required to (i) induce the coagulation of coal particles and (ii) effectively disperse particles of mineral matter. If the coal is oxidized, a small dosage of reagents can be used to enhance the process. The technical work program was initiated on July 1, 1992. Force-distance curves were generated for DDOA Br-coated mica surfaces in water and used to calculate hydrophobicity constants and decay lengths for this system; and a new device for the measurement of water contact angles, similar to the Wilhelmy plate balance, has been built 225 kg samples of Pittsburgh No. 8 and Elkhom No. 3 seam coals were obtained; a static mixer test facility for the study of coagula growth was set up and was undergoing shakedown tests at the end of the quarter; a bench-scale lamella thickener was being constructed; and preliminary coagula/ mineral separation tests were being conducted in a bench-scale continuous drum filter.
Surface modification of cellulose fibers. II. The effect of cellulose fiber treatment on the performance of cellulose–polyester composites (1985)

Abstract Cellulose fibers treated with different coupling agents based on trichloro‐ s ‐triazine have been evaluated in terms of their reinforcement effect on unsaturated polyesters. The treatment with coupling agents containing double bonds resulted in what we believe to be the formation of covalent bonds between fiber and matrix. This has been compared with a treatment, which can only lead to formation of close interfacial molecular contact by wetting. The tensile properties of composites prepared from treated and untreated fibers were studied before and after exposure to water. It was found that all types of fiber treatment decreased water absorption and the reduction of mechanical properties in wet conditions, but that the degradation at the fiber/matrix interface which occurs from immersion in water and drying could only be avoided through the development of covalent bonds between fiber and matrix. Scanning electron microscopy was used to study the adhesion between fiber and matrix. An explanation of the reduction of mechanical properties of cellulose‐fiber reinforced polymers in wet conditions is proposed.
Optical Crossbar Interconnected Digital Signal Processor With Basic Algorithms (1986)

A proposed high performance gigaflop signal processor is described in which 512 processors are interconnected with a 768 by 768 crossbar switch utilizing a spatial light modulator of the type presently under development at Texas Instruments. Optical fibers are used to provide high speed communication between the processors and the switch. The system, processor nodes, programming, and functional operation are described. The advantages are discussed for reconfigurability, optical crossbar switches, and programmed data flow. Efficient implementations are presented for a systolic filter, a fast Fourier transform, a correlator, and a matrix-vector multiplier. Preliminary performance estimates suggest that over one gigaflop performance is achievable for these algorithms on this processor.
Estimation of in-cylinder pressure using spark plug discharge current measurements (2013)

In-cylinder pressure of spark ignition engines is correlated with several variables of the compression, injection, and ignition processes. Therefore, by monitoring the pressure of each cylinder we can improve the electronic engine supervision and control in terms of fast response and accuracy, thus enabling online diagnosis and overall efficiency improvement. However, the pressure measurement methods proposed until now have not been generally accepted at the production level due to their cost and/or complexity. In this paper we describe a novel approach that derives the pressure information from the measurement of the ordinary spark plug discharge current. In this manner, the mechanical part of the engine does not require substantial modification. To demonstrate the viability of the proposed technique, a prototype measurement system was set up and tested. Preliminary experimental data show that pressure in stationary conditions can be estimated with an error lower than 5% for pressure above 3 atmospheres.
Arabie sign language recognition using the Microsoft Kinect (2016)

Several studies have been carried on sign language recognition systems, however, practically deployable system for real-time use is still a challenge. Traditionally, sign language recognition systems have either used sensor gloves or digital cameras to acquire and process hand gestures. Both approaches exhibit some disadvantages for real time deployment that hindered it large scale adoption. With the growth witnessed in gaming systems, two new instruments have been introduced namely, the Microsoft Kinect (MK) and the leap motion controller. The MK system has been developed to interact with video games by tracking full body movements and gestures. To overcome some of the disadvantages of the classical methods, we propose here to develop an Arabic sign language recognition system based on MK system. The developed system was tested with 20 signs from the Arabic sign language dictionary. Therefore, in this paper, we present our experiment carried out using the MK setup on 20 Arabic sign language words. Video samples of both true color images and depth images were collected from native deaf signer. Linear Discriminant analysis was used for feature dimension reduction and sign classification. Furthermore, fusion from RGB and depth sensor was carried at feature and decision level giving an overall best accuracy of 99.8%.
<i>Pseudomonas</i> exotoxin: recombinant conjugates as therapeutic agents (1992)

Conference Article| November 01 1992 Pseudomonas exotoxin: recombinant conjugates as therapeutic agents David J. FitzGerald; David J. FitzGerald 1Laboratory of Molecular Biology, Department of Health and Human Services, National Cancer Institute, Bethesda, Maryland 20892, U.S.A. Search for other works by this author on: This Site PubMed Google Scholar Ira Pastan Ira Pastan 1Laboratory of Molecular Biology, Department of Health and Human Services, National Cancer Institute, Bethesda, Maryland 20892, U.S.A. Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1992) 20 (4): 731–734. https://doi.org/10.1042/bst0200731 Article history Received: July 23 1992 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Citation David J. FitzGerald, Ira Pastan; Pseudomonas exotoxin: recombinant conjugates as therapeutic agents. Biochem Soc Trans 1 November 1992; 20 (4): 731–734. doi: https://doi.org/10.1042/bst0200731 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search Keywords: PE, Pseudomonas exotoxin, EF-2, elongation factor-2, Ab, antibody This content is only available as a PDF. © 1992 Biochemical Society1992 Article PDF first page preview Close Modal You do not currently have access to this content.
Ferroelectrically switchable columnar liquid crystal (1992)

Abstract The synthesis of a new disc-like mesogenic compound permitted, for the first time, ferroelectric electrooptical switching in a tilted columnar liquid crystal. The spontaneous molecular dipole moment is induced by the bend between the dibenzopyrene core and part of the eight O-hexyllactic acid chains attached to it. Two similar new compounds displayed a weak electrooptical effect in the columnar phase.
Exploiting error-control coding and cyclic-prefix in channel estimation for coded OFDM systems (2004)

OFDM systems typically use coding and interleaving across subchannels to exploit frequency diversity on frequency-selective channels. This paper presents a low-complexity iterative algorithm for combined blind and semi-blind channel estimation and soft decoding in coded OFDM systems. Channel estimation is performed in the time domain using the expectation maximization (EM) algorithm to take advantage of the channel-length constraint and the extra observation offered by the cyclic-prefix. The proposed technique converges within a single OFDM symbol and, therefore, has a minimum latency and is suitable for fast time-varying channels.