gebhart/patrepeval huggingface dataset:
Physicochemical properties of bactericidal plasma-treated water (2016)

Plasma-treated water (PTW), i.e. distilled water (DW) exposed to low-temperature atmospheric pressure helium plasma, exhibited strong bactericidal activity against Escherichia coli in suspension even within a few minutes of preparation. This effect was enhanced under acidic conditions. The bactericidal activity of PTW was attenuated according to first-order kinetics and the half-life was highly temperature dependent. The electron spin resonance (ESR) signal of an adduct of the superoxide anion radical () was detected in an aqueous solution using a spin-trapping reagent mixed with PTW, and adding superoxide dismutase to the PTW resulted in a loss of the bactericidal activity and weakening of the ESR adduct signal of in the spin-trapping. These results suggest that plays an important role in imparting bactericidal activity to PTW. Moreover, molecular nitrogen was required both in the ambient gas and in the DW used to prepare the PTW. We, therefore, suggest that the reactive molecule in PTW with bactericidal effects is not a free reactive oxygen species but nitrogen atom(s)-containing molecules that release , such as peroxynitrous acid (ONOOH) or peroxynitric acid (O2NOOH). Considering the activation energy for degradation of these species, we conclude that peroxynitric acid stored in PTW induces the bactericidal effect.
Enzyme‐Responsive Nanoparticles for Targeted Accumulation and Prolonged Retention in Heart Tissue after Myocardial Infarction (2015)

A method for targeting to and retaining intravenously injected nanoparticles at the site of acute myocardial infarction in a rat model is described. Enzyme-responsive peptide-polymer amphiphiles are assembled as spherical micellar nanoparticles, and undergo a morphological transition from spherical-shaped, discrete materials to network-like assemblies when acted upon by matrix metalloproteinases (MMP-2 and MMP-9), which are up-regulated in heart tissue post-myocardial infarction.
A Cost-Space Approach to Distributed Query Optimization in Stream Based Overlays (2005)

Distributed stream-based applications, such as continuous query systems, have network scale and time characteristics that challenge traditional distributed query optimization. The optimization sub-problems of plan generation and service placement should be integrated to meet these challenges. These tasks have typically been treated as independent sub-problems because of the complexity of their integration. We suggest cost spaces as one way to mitigate this complexity. We further consider how cost spaces can be used to allow tractable multi-query optimization.
Designing a Tourism Recommender System Based on Location, Mobile Device and User Features in Museum (2012)

Today, mobile devices are widely used by many tourists. They can use mobile for accessing information about all sightseeing around the world. On the other hand, it seems essential to personalize the content due to diversity of learners and variation of the tools they use. On the whole, the goal for personalization is to suggest a collection of comprehensive activities, taking into consideration factors such as location, user preferences and interests and so on. One of the applications of recommender systems is in tourism industry. Mobile devices can be used in sites such as museums. Demands of different people such as students, tourists and ordinary people can be met in spite of their diverse features and preferences. The purpose of this paper is to give a model which is able to recommend new locations to visitors in a museum while the visitor is given essential information about the certain features of the suggested site.
Adsorption of Pesticides on Resins (2003)

The objective of this work was to assess the capability of organic hydrophobic polymeric resins Amberlite XAD-4 and XAD-7 to remove the pesticides alachlor and amitrole from water. The pesticides adsorption on the two different adsorbents was measured by batch equilibrium technique and isotherm types and parameters were estimated. Two theoretical models were applied based on a Freundlich and a Langmuir isotherms. The effect of pesticides chemical composition and structure as well as the nature of solid surface on the efficiency of adsorption was evaluated. The influence of pH also was studied. In low pH solutions adsorption of amitrole was higher upon the nonionic aliphatic acrylic ester copolymer XAD-7 in comparison to the nonionic, crosslinked macroreticular copolymer of styrene divinylbenzene XAD-4. In neutral and intermediate pH solutions the polar acrylic ester copolymer XAD-7 was more effective to the retention of alachlor. The acrylic ester copolymer showed at pH 3 the lower effectiveness in alachlor removal from water. The data of the adsorption isotherms of pesticides upon the examined polymeric resins seemed to conform to both the Freundlich and the Langmuir isotherm models.
Simulating Energy Transfer and Upconversion in β-NaYF<sub>4</sub>: Yb<sup>3+</sup>, Tm<sup>3+</sup> (2015)

The design of upconversion phosphors with higher quantum yield requires a deeper understanding of the detailed energy transfer and upconversion processes between active ions inside the material. Rate equations can model those processes by describing the populations of the energy levels of the ions as a function of time. However, this model presents some drawbacks: energy migration is assumed to be infinitely fast, it does not determine the detailed interaction mechanism (multipolar or exchange), and it only provides the macroscopic averaged parameters of interaction. Hence, a rate equation model with the same parameters cannot correctly predict the time evolution of upconverted emission and power dependence under a wide range of concentrations of active ions. We present a model that combines information about the host material lattice, the concentration of active ions, and a microscopic rate equation system. The extent of energy migration is correctly taken into account because the energy transfer processes are described on the level of the individual ions. This model predicts the decay curves, concentration, and excitation power dependences of the emission. This detailed information can be used to predict the optimal concentration that results in the maximum upconverted emission.
Structure-dependent dynamic mechanical behavior of fibrous caps from human atherosclerotic plaques. (1991)

We conclude that the stiffness of fibrous caps from human atherosclerotic plaques is related to the underlying histological structure and that the stiffness increases with frequency in the range of physiological heart rates. The protective benefit of beta-adrenergic receptor blocking agents in coronary artery disease may, in part, be related to the frequency dependence of atherosclerotic plaque stiffness.
Colistin resistance of Acinetobacter baumannii: clinical reports, mechanisms and antimicrobial strategies (2012)

Colistin is the last resort for treatment of multidrug-resistant Acinetobacter baumannii. Unfortunately, resistance to colistin has been reported all over the world. The highest resistance rate was reported in Asia, followed by Europe. The heteroresistance rate of A. baumannii to colistin is generally higher than the resistance rate. The mechanism of resistance might be loss of lipopolysaccharide or/and the PmrAB two-component system. Pharmacokinetic/pharmacodynamic studies revealed that colistin monotherapy is unable to prevent resistance, and combination therapy might be the best antimicrobial strategy against colistin-resistant A. baumannii. Colistin/rifampicin and colistin/carbapenem are the most studied combinations that showed promising results in vitro, in vivo and in the clinic. New peptides showing good activity against colistin-resistant A. baumannii are also being investigated.
Sequential‐color LCD based on OCB with an LED backlight (2002)

Abstract— We have fabricated a 13.3‐in. XGA (1024 × 768) TFT sequential‐color liquid‐crystal display using optically compensated birefringency (OCB), illuminated by an LED backlight. We fabricated the sequential‐color display feasible process technology, and examined the performance and potential of a field‐sequential‐color scheme. The display was connected to a laptop computer and examined for flicker.
Produkte der Dimerisierung ungesättigter Fettsäuren VII: Kinetische Untersuchung der Mono‐ und Dimeren, die bei der Dimerisierung von Ölsäure entstehen (1992)

Abstract Aus einem Gemisch von 95%iger Ölsäure, die mit 5% Linolsäure verunreinigt war, wurden während der „Dimerisierung”︁ Proben entnommen. Diese Untersuchungen zeigen, daß Ölsäure zuerst in Elaidinsäure und Doppelbindungsstellungsisomere umgewandelt wird. Ausschließlich aus diesen Verbindungen entstehen die sogenannten „Isostearinsäuren”︁, die man in der Monomerfraktion findet. Belegt wird dieser Befund durch die Dimerisierung von reiner Elaidinsäure, aus der identische Produkte in identischen Mengen entstehen. Primäre Dimerisierungsprodukte dieses Gemisches von 95% Ölsäure und 5% Linolsäure sind solche, die aus zwei Molekülen Linolsäure bzw. einem Linolsäuremolekül mit einem Ölsäuremolekül entstehen. Diese Stoffe haben teils cyclische, teils alicyclische Struktur. Eine Isomerisierung und Hydrierung erfolgt erst im späteren Reaktionsverlauf.
Mock Object Models for Test Driven Development (2006)

Test driven development uses unit tests for driving the design of the code. Mock object is an object that imitates the behavior of an object with which class under test has an association to assist the unit testing. Although many tools for mock object are used in practice, there has been few research on defining the mock object model. For the comparisons of the testing capability of the tools, it is important to define the models. In this paper we represent the models of the existing mock object tools and indicate the limitations of them. In addition we propose a new model to overcome the limitations of the existing tools. With this model, more general behavior of the class under test related to the mock object can be expressed and tested.
III-V multi-junction solar cell using metal wrap through contacts (2016)

The Solar cell front side is a key design point for improved cell efficiency as a trade is made between optical losses (shadowing effect) and electrical losses (resistance). One solution consists in frontside contacts report to the cell’s backside using through device conductive vias. By this way metal shadowing could be drastically reduced without increasing resistive losses. Such architecture is called Metal Wrap Through (MWT) and has been developed on silicon solar cells. Its application to III-V Multi-Junctions Solar Cells (MJSC) could be of great interest and has been simulated and studied for several years. We present here first functional MWT III-V dual-junction solar cells. Prototype developments have been based on inverted tandem solar cell (GaInP/GaAs) epitaxial structures grown on GaAs substrates. Front side contacts have been reported on the device’s backside using specifically adapted Trough Semiconductor Via (TSV) technologies. Finally, the III-V active film was transferred on a conductive receiver by copper to copper (Cu//Cu) direct metal bonding. Morphological and chemical characterizations showed metallized and isolated contacts going through the tandem solar cell’s structure. Electrical characterizations displayed many functional cells across 100mm wafers reaching efficiencies up to 26.3% @1 sun AM1.5d spectrum with a fill factor (FF) of 87.1%. Under concentration the efficiency raised up to 28.3% @167 suns. Beside these demonstrators, developed processes open ways to various possibilities such as large area III-V MJSC receivers.
Coaxial cable cutter (2023)

A cutting device is provided which is useful in trimming the jackets from semi-rigid coaxial cables and wire having a cutting bit and support attached to movable jaws. A thumbpiece is provided to actuate the opening of the jaws for receiving the cable to be trimmed, and a spring member is provided to actuate the closing of the jaws when thumbpiece is released. The cutting device utilizes one moving part during the cutting operation by using a rolling cut action. The nature of the jaws allows the cutting device to work in space having clearances less than 0.160 inches.
Nucleotides of 18S rRNA surrounding mRNA codons at the human ribosomal A, P, and E sites: A crosslinking study with mRNA analogs carrying an aryl azide group at either the uracil or the guanine residue (2000)

The 18S rRNA environment of the mRNA at the decoding site of human 80S ribosomes has been studied by cross-linking with derivatives of hexaribonucleotide UUUGUU (comprising Phe and Val codons) that carried a perfluorophenylazide group either at the N7 atom of the guanine or at the C5 atom of the 5'-terminal uracil residue. The location of the codons on the ribosome at A, P, or E sites has been adjusted by the cognate tRNAs. Three types of complexes have been obtained for each type derivative, namely, (1) codon UUU and Phe-tRNAPhe at the P site (codon GUU at the A site), (2) codon UUU and tRNAPhe at the P site and PheVal-tRNAVal at the A site, and (3) codon GUU and Val-tRNAVal at the P site (codon UUU at the E site). This allowed the placement of modified nucleotides of the mRNA analog at positions -3, +1, or +4 on the ribosome. Mild UV irradiation resulted in tRNA-dependent crosslinking of the mRNA analogs to the 18S rRNA. Nucleotide G961 crosslinked to mRNA position -3, nucleotide G1207 to position +1, and A1823 together with A1824 to position +4. All of these nucleotides are located in the most strongly conserved regions of the small subunit RNA structure, and correspond to nucleotides G693, G926, G1491, and A1492 of bacterial 16S rRNA. Three of them (with the exception of G1491) had been found earlier at the 70S ribosomal decoding site. The similarities and differences between the 16S and 18S rRNA decoding sites are discussed.
Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation (2008)

Human mitochondrial DNA is widely used as tool in many fields including evolutionary anthropology and population history, medical genetics, genetic genealogy, and forensic science. Many applications require detailed knowledge about the phylogenetic relationship of mtDNA variants. Although the phylogenetic resolution of global human mtDNA diversity has greatly improved as a result of increasing sequencing efforts of complete mtDNA genomes, an updated overall mtDNA tree is currently not available. In order to facilitate a better use of known mtDNA variation, we have constructed an updated comprehensive phylogeny of global human mtDNA variation, based on both coding- and control region mutations. This complete mtDNA tree includes previously published as well as newly identified haplogroups, is easily navigable, will be continuously and regularly updated in the future, and is online available at http://www.phylotree.org.
MAIN DISEASES AND INJURIES RELATED TO OCCUPATIONAL ACTIVITIES, PREVENTION AND TREATMENT (2023)

RSI/DORT is an acronym for Repetitive Strain Injuries and Work-Related Musculoskeletal Disorders, a set of clinical conditions that affect muscles, tendons, nerves and joints in workers from different professional areas (BRASIL, 2017).Injuries occur when there is an imbalance between the physical load required by work and the worker's ability to support it.
PITX2 and β-Catenin Interactions Regulate Lef-1 Isoform Expression (2007)

Lef-1 and PITX2 function in the Wnt signaling pathway by recruiting and interacting with beta-catenin to activate target genes. Chromatin immunoprecipitation (ChIP) assays identified the Lef-1 promoter as a PITX2 downstream target. Transgenic mice expressing LacZ driven by the 2.5-kb LEF-1 promoter demonstrated expression in the tooth epithelium correlated with endogenous Lef-1 FL epithelial expression. PITX2 isoforms regulate the LEF-1 promoter, and beta-catenin synergistically enhanced activation of the LEF-1 promoter in combination with PITX2 and Lef-1 isoforms. PITX2 enhances endogenous expression of the full-length beta-catenin-dependent Lef-1 isoform (Lef-1 FL) while decreasing expression of the N-terminally truncated beta-catenin-independent isoform. Our research revealed a novel interaction between PITX2, Lef-1, and beta-catenin in which the Lef-1 beta-catenin binding domain is dispensable for its interaction with PITX2. PITX2 interacts with two sites within the Lef-1 protein. Furthermore, beta-catenin interacts with the PITX2 homeodomain and Lef-1 interacts with the PITX2 C-terminal tail. Lef-1 and beta-catenin interact simultaneously and independently with PITX2 through two different sites to regulate PITX2 transcriptional activity. These data support a role for PITX2 in cell proliferation, migration, and cell division through differential Lef-1 isoform expression and interactions with Lef-1 and beta-catenin.
Newer Stents: Materials and Designs. (1997)

We aim to present here the experience with newer stents for coronary and peripheral interventions. Specifically, the design and technical considerations of the self-expanding nitinol coil stents for coronary and vascular indications, as well as the design and clinical experience with the tubular stainless steel balloon-expandable serpentine stents for coronary and peripheral interventions are discussed. The animal and clinical experience with both types of stent have shown that the mechanisms of deployment and expansion are different for these inherently different stents. The self-expanding coil stent, providing adequate scaffolding in various types of coronary lesions is deployed by self expansion, aided to a significant extent by balloon expansion. Long-term outside pressure on the wall may lead to further stent expansion as has been shown with this stent, which may be an important parameter in the restenosis process. The tubular balloon-expandable serpentine stent does not have the feature of long-term expansion, however, is characterized by superior scaffolding properties and unique features that allow its safe use in the most complex coronary diseases. Long-term clinical results are pending for these two families of stents.
Lamotrigine Treatment for Affective Instability in Adolescents With Borderline Personality Disorder (2012)

Patients with BPD are characterized by a pervasive pattern of instability in affect regulation, impulse control, interpersonal relationships, and self-image. The efficacy of fluvoxamine and lamotrigine for affective instability in patients with BPD has been shown in controlled studies. However, no study has evaluated the effectiveness and safety of lamotrigine for treating irritability in adolescent patients with BPD in Japan. Here, we report the case of a patient with BPD whose condition improved after lamotrigine administration. Lamotrigine could be effective and safe for treating BPD-associated affective instability. However, large-scale controlled studies are needed to confirm our findings.
Pyruvic Acid Peels for the Treatment of Photoaging (2004)

BACKGROUND Pyruvic acid (CH3-CO-COOH), an α-keto-acid, has been recently used as a medium chemical peeling agent in subjects with inflammatory acne, moderate acne scars, greasy skin, actinic keratosis, and warts. OBJECTIVE The aim of our study was to evaluate the efficacy and tolerability of 50% pyruvic acid on moderately photodamaged facial skin. METHODS We treated 20 patients with four peeling sessions at 4-week intervals. We evaluated the patients clinically, and in order to obtain an objective assessment of the effect of pyruvic acid on pigmentary components of the skin, erythema and hyperpigmentation response were measured in all the patients before and after treatment using a Minolta Tri-Stimulus Colorimeter II. RESULTS The clinical evaluation of the patients after the peeling sessions demonstrated a smoother texture, less evident fine wrinkles, and evident lightening of hyperpigmentations (freckles and lentigines). In fact, chemical peels cause a thinning of the epidermis and a thickening of the dermis. The patients treated reported very limited or no discomfort in the postpeel period. CONCLUSION Thus, 50% pyruvic acid peeling can be proposed as a safe and efficient treatment for moderate facial skin aging.
A highly evolutionarily conserved mitochondrial protein is structurally related to the protein encoded by the Escherichia coli groEL gene. (1988)

We recently reported that a Tetrahymena thermophila 58-kilodalton (kDa) mitochondrial protein (hsp58) was selectively synthesized during heat shock. In this study, we show that hsp58 displayed antigenic similarity with mitochondrially associated proteins from Saccharomyces cerevisiae (64 kDa), Xenopus laevis (60 kDa), Zea mays (62 kDa), and human cells (59 kDa). Furthermore, a 58-kDa protein from Escherichia coli also exhibited antigenic cross-reactivity to an antiserum directed against the T. thermophila mitochondrial protein. The proteins from S. cerevisiae and E. coli antigenically related to hsp58 were studied in detail and found to share several other characteristics with hsp58, including heat inducibility and the property of associating into distinct oligomeric complexes. The T. thermophila, S. cerevisiae, and E. coli macromolecular complexes containing these related proteins had similar sedimentation characteristics and virtually identical morphologies as seen with the electron microscope. The distinctive properties of the E. coli homolog to T. thermophila hsp58 indicate that it is most likely the product of the groEL gene.
System power distribution network theory and performance with various noise current stimuli including impacts on chip level timing (2009)

Power Quality has become a determining factor in product performance and reliability. The reactive portions of the power distribution network (PDN) have a greater effect on power quality than DC IR drop. Resonance in the parallel inductance and capacitance network creates an impedance peak in the frequency domain and undesirable voltage noise in the time domain. The on-chip voltage noise is usually much higher than PCB PDN noise. A method of determining and simulating circuit parameters and comparing results to a target impedance is presented. A test vehicle has been built and measured to provide laboratory measured results for PDN voltage noise. Switching current patterns are defined which generate typical and pathological voltage waveforms. PRBS patterns are used as a characterization technique to provide reasonable worst case resonance stimulation. The voltage noise is responsible for measured timing and jitter degradation in logic circuits.
Polymeric hollow fibers for capillary electrophoresis (1993)

Abstract In this paper, polymeric hollow fibers prepared from polypropylene and polybutylene terephthalate were used as CE columns. Surface modifications with polyacrylamide greatly improved the performance of the capillaries. Separations of substituted pyridines, model proteins and standard ribonucleotides were demonstrated. The column efficiency for model proteins was over 200,000 theoretical plates. Comparisons of electroosmotic flow, UV absorption properties, heat dissipation, and diameter variation between fused silica capillaries and polymeric hollow fibers were made. The practical potential of small diameter polymeric hollow fibers as CE columns was evaluated.