gebhart/patrepeval huggingface dataset:
Finding frequent items in data streams (2008)

The frequent items problem is to process a stream of items and find all items occurring more than a given fraction of the time. It is one of the most heavily studied problems in data stream mining, dating back to the 1980s. Many applications rely directly or indirectly on finding the frequent items, and implementations are in use in large scale industrial systems. However, there has not been much comparison of the different methods under uniform experimental conditions. It is common to find papers touching on this topic in which important related work is mischaracterized, overlooked, or reinvented. In this paper, we aim to present the most important algorithms for this problem in a common framework. We have created baseline implementations of the algorithms, and used these to perform a thorough experimental study of their properties. We give empirical evidence that there is considerable variation in the performance of frequent items algorithms. The best methods can be implemented to find frequent items with high accuracy using only tens of kilobytes of memory, at rates of millions of items per second on cheap modern hardware.
IL10 and Neuropathic Pain (2008)

Proinflammatory cytokines are known to play a role in promoting neuropathic pain. Antiinflammatory cytokines, including IL10, may therefore represent a way of modulating this pain. Do repeated intr...
Atomic Force Microscopy of Humic Substances:  Effects of pH and Ionic Strength (1999)

Tapping mode atomic force microscopy was employed to determine the shape, size, and properties of the Suwannee River humic acid and a U.K. Geological Survey peat humic acid sorbed to mica. Humic acid macromolecules are shown to have a globular shape with an adsorbed height between 0.5 and 2 nm for a concentration of 10 mg L-1, pH > 5, and I < 500 mM NaCl. Aggregation of the humic macromolecules was not systematically observed at low pH and ionic strength. Instead aggregation may have been to be related to the hydrophobicity of the sample: no aggregates were observed for the relatively hydrophilic Suwannee River humic acid between pH 3 and pH 10 (I = 5−50 mM), while aggregates of peat humic acid were observed at low pH (pH < 5) and high ionic strength (I ∼ 500 mM). Calculated and measured hydrodynamic diameters determined under the same conditions were found to be systematically slightly larger than AFM heights, in good agreement with expectations given the different nature of the two measurements.
Molecular characterization of the tdc operon of Escherichia coli K-12 (1988)

The nucleotide sequence of a 2-kilobase DNA fragment of the tdc region of Escherichia coli K-12, previously cloned in this laboratory, revealed two open reading frames, tdcC and ORFX, downstream from the tdcB gene (formerly designated tdc) encoding biodegradative threonine dehydratase. A 24-base-pair sequence separated tdcC from the dehydratase coding region, and an untranslated region of 60 nucleotides, which contains a recognizable -10 consensus sequence, was found between tdcC and ORFX. The deduced amino acid sequence of tdcC showed it to be a large hydrophobic polypeptide of 431 amino acid residues, whereas ORFX coded for a small 135-residue polypeptide lacking glutamine and tryptophan. A computer-assisted sequence analysis revealed no similarity among the tdcB, tdcC, and ORFX polypeptides, and a search of the GenBank database failed to detect similarity with any other known proteins. The tdc genes and ORFX showed similar codon usage and, in analogy with other bacterial genes, showed codon usage typical for genes expressed at an intermediate level. Transcriptional analysis with S1 nuclease indicated two distinct transcription start sites upstream of the tdcB gene in regions previously identified as promoterlike elements P1 and P2. Interestingly, expression of tdcB and tdcC, but not ORFX, was contingent upon the presence of P1. These results taken together tend to suggest that the biodegradative threonine dehydratase is the second gene in a polycistronic transcription unit constituting a novel operon (tdcABC) in E. coli implicated in anaerobic threonine metabolism.
Effects of Solvent on Powder Characteristics of Zinc Oxide and Magnesia Prepared by Flame Spray Pyrolysis (2005)

Zinc oxide (ZnO) and magnesia (MgO) powders were made by flame spray pyrolysis of zinc acetate and magnesium acetate, respectively, dissolved in methanol-water mixture. The product powders were characterized by nitrogen adsorption, infrared adsorption (IR), X-ray diffraction (XRD) and transmission electron microscopy. The effects of solvent on powder characteristics were examined by changing methanol content (X=1-0.4) in the solvent. Polyhedral aggregates of nanoparticles were formed from the precursor solution with X=1-0.6 for both ZnO and MgO syntheses, suggesting complete evaporation of the metal species and particle formation in the gas phase. Decrease of the methanol content to X=0.4 lowered the spray flame temperatures, suppressing complete evaporation, resulting in a mixture of nanoparticles and large (e.q.>100 nm) particles for both ZnO and MgO synthesis. On the other hand, the XRD and IR spectra indicated partial hydroxide formation for MgO synthesis, differed from ZnO synthesis. The reaction with water vapor in the combustion gas can be enhanced for MgO because of the larger Gibbs energy change for hydroxylation in MgO than in ZnO.
Personalized recommendation in social tagging systems using hierarchical clustering (2008)

Collaborative tagging applications allow Internet users to annotate resources with personalized tags. The complex network created by many annotations, often called a folksonomy, permits users the freedom to explore tags, resources or even other user's profiles unbound from a rigid predefined conceptual hierarchy. However, the freedom afforded users comes at a cost: an uncontrolled vocabulary can result in tag redundancy and ambiguity hindering navigation. Data mining techniques, such as clustering, provide a means to remedy these problems by identifying trends and reducing noise. Tag clusters can also be used as the basis for effective personalized recommendation assisting users in navigation. We present a personalization algorithm for recommendation in folksonomies which relies on hierarchical tag clusters. Our basic recommendation framework is independent of the clustering method, but we use a context-dependent variant of hierarchical agglomerative clustering which takes into account the user's current navigation context in cluster selection. We present extensive experimental results on two real world dataset. While the personalization algorithm is successful in both cases, our results suggest that folksonomies encompassing only one topic domain, rather than many topics, present an easier target for recommendation, perhaps because they are more focused and often less sparse. Furthermore, context dependent cluster selection, an integral step in our personalization algorithm, demonstrates more utility for recommendation in multi-topic folksonomies than in single-topic folksonomies. This observation suggests that topic selection is an important strategy for recommendation in multi-topic folksonomies.
Epitaxial Lift-Off Technology for Large Size III–V-on-Insulator Substrate (2019)

III-V materials can be a very good channel candidate for monolithic 3D (M3D) integration due to the potential of high-performance and lower process temperature as compared with Si, since a low process temperature is crucial to avoid degradation of bottom devices. For III-V M3D integration, material transfer techniques are important, and such processes should be enabled by low process costs on a large wafer scale. In this study, we propose an InGaAs channel transfer technique by wafer bonding, epitaxial lift-off and III-V layers grown on Si substrate. Effective mobility of fabricated MOS HEMTs using transferred InGaAs layer was 1.3 times higher than that of Si MOSFETs. The proposing channel transfer technique would be useful for M3D integration because it provides wafer scalability, cost-effectiveness, back-gate biasing, and etc.
Interlinking Unstructured and Structured Knowledge in an Integrated Framework (2013)

Despite the widespread diffusion of structured data sources and the public acclaim of the Linked Open Data initiative, a preponderant amount of information remains nowadays available only in unstructured form, both on the Web and within organizations. While different in form, structured and unstructured contents speak about the very same entities of the world, their properties and relations, still, frameworks for their seamless integration are lacking. In this paper we describe the design of the Knowledge Store, a scalable, fault-tolerant, and Semantic Web grounded storage system for interlinking structured and unstructured data. We discuss its capability to adapt to new types of content and application scenarios, and to provide reasoning and semantic queries services on top of stored contents. We also comment on its envisaged use in the News Reader EU project to manage large amounts of economical-financial data.
Improving java virtual machine reliability for memory-constrained embedded systems (2005)

Dual-execution/checkpointing based transient error tolerance techniques have been widely used in the high-end mission critical systems. These techniques, however, are not very attractive for cost-sensitive embedded systems because they require extra resources (e.g., large memory, special hardware, etc), and thus increase overall cost of the system. In this paper, we propose a transient error tolerant Java Virtual Machine (JVM) implementation for embedded systems. Our JVM uses dual-execution and checkpointing to detect and recover from transient errors. However, our technique does not require any special hardware support (except for the memory page protection mechanism, which is commonly available in modern embedded processors), and the memory space overhead it incurs is not excessive. Therefore, it is suitable for memory-constrained embedded systems. We implemented our approach and performed experiments with seven embedded Java applications.
Evaluation and extension of the two-site, two-step model for binding and activation of the chemokine receptor CCR1 (2018)

Interactions between secreted immune proteins called chemokines and their cognate G protein-coupled receptors regulate the trafficking of leukocytes in inflammatory responses. The two-site, two-step model describes these interactions. It involves initial binding of the chemokine N-loop/β3 region to the receptor's N-terminal region and subsequent insertion of the chemokine N-terminal region into the transmembrane helical bundle of the receptor concurrent with receptor activation. Here, we test aspects of this model with C-C motif chemokine receptor 1 (CCR1) and several chemokine ligands. First, we compared the chemokine-binding affinities of CCR1 with those of peptides corresponding to the CCR1 N-terminal region. Relatively low affinities of the peptides and poor correlations between CCR1 and peptide affinities indicated that other regions of the receptor may contribute to binding affinity. Second, we evaluated the contributions of the two CCR1-interacting regions of the cognate chemokine ligand CCL7 (formerly monocyte chemoattractant protein-3 (MCP-3)) using chimeras between CCL7 and the non-cognate ligand CCL2 (formerly MCP-1). The results revealed that the chemokine N-terminal region contributes significantly to binding affinity but that differences in binding affinity do not completely account for differences in receptor activation. On the basis of these observations, we propose an elaboration of the two-site, two-step model-the "three-step" model-in which initial interactions of the first site result in low-affinity, nonspecific binding; rate-limiting engagement of the second site enables high-affinity, specific binding; and subsequent conformational rearrangement gives rise to receptor activation.
Neurohormonal Activation and the Chronic Heart Failure Syndrome in Adults With Congenital Heart Disease (2002)

Neurohormonal activation in adult congenital heart disease bears the hallmarks of chronic heart failure, relating to symptom severity and ventricular dysfunction and not necessarily to anatomic substrate. Neurohormonal antagonism across this large and anatomically diverse population should be considered.
A New Green Composite Based on Plasticized Polylactic Acid Mixed with Date Palm Waste for Single-Use Plastics Applications (2022)

Petroleum-based plastic is widely used in almost all fields. However, it causes serious threats to the environment owing to its non-biodegradable properties, which necessitates finding biodegradable alternatives. Here, date palm rachis (DPR) waste was used as a filler (30, 40, and 50 wt%) to form a biodegradable composite with polylactic acid (PLA) and achieve cost-performance balance. DPR-PLA composites were prepared using a melt-mixing extruder at 180 °C by varying mixing time, DPR composition, and plasticizer type and composition. The biodegradable testing specimens were prepared by compression molding and analyzed using physical, thermal, and mechanical characterizations. Scanning electron microscopy images indicated a uniform dispersion of DPR (90 μm) in the PLA matrix. The esterification reaction resulting from this interaction between DPR and PLA was confirmed by Fourier transform infrared spectroscopy. The 30 wt% DPR-PLA composite was considered the optimal composite with the lowest melt flow index (16 g/10 min). This work confirmed the superior effect of addition of 10 wt% of triethyl citrate (TEC) compared with polybutylene adipate terephthalate (PBAT) by the improvement in the elongation at break of the optimal composite from 2.10% to 4.20%. Moreover, the addition of 10 wt% of PBAT to the optimal composite resulted in a lower tensile strength (21.80 MPa) than that of the composite with 10 wt% of TEC (33.20 MPa). These results show the potential of using the proposed composite as an alternative material for single-use plastics such as cutlery.
Mycothiol, 1‐<i>O</i>‐(2′‐[<i>N</i>‐acetyl‐<scp>L</scp>‐cysteinyl]amido‐2′‐deoxy‐α‐<scp>D</scp>‐glucopyranosyl)‐<scp>D</scp>‐<i>myo</i>‐inositol, is the factor of NAD/factor‐dependent formaldehyde dehydrogenase (1997)

Two different NAD/coenzyme-dependent formaldehyde dehydrogenases exist, the well-known NAD/GSH-dependent (EC 1.2.1.1) and the more recently discovered NAD/Factor-dependent enzyme. The GSH-dependent one has been found in eukaryotes and Gram-negative bacteria, the Factor-dependent one in two different Gram-positive bacteria. Previous work also showed that Factor and GSH are not interchangeable in the enzymatic reactions. Here it is revealed that the Factor is identical to mycothiol (MySH), 1-O-(2'-[N-acetyl-L-cysteinyl]-amido-2'-deoxy-alpha-D-glucopyranosyl)-D- myo-inositol, a thiol compound which has recently been detected in Actinomycetes. Thus, MySH is GSH's companion as it is the coenzyme for the enzyme which henceforth can be indicated as NAD/MySH-dependent formaldehyde dehydrogenase.
Reduction of stress‐induced analgesia but not of exogenous opioid effects in mice lacking CB<sub>1</sub> receptors (2000)

CB1 cannabinoid receptors are widely distributed in the central nervous system where they mediate most of the cannabinoid-induced responses. Here we have evaluated the interactions between the CB1 cannabinoid receptors and the endogenous opioid system by assaying a number of well-characterized opioid responses, e.g. antinociception and stress-mediated effects, on mutant mice in which the CB1 receptor gene was invalidated. The spontaneous responses to various nociceptive stimuli (thermal, mechanical and visceral pain) were not changed in mutant CB1 mice. Furthermore, the absence of the CB1 cannabinoid receptor did not modify the antinociceptive effects induced by different opioid agonists: morphine (preferential mu opioid agonist), D-Pen2-D-Pen5-enkephalin (DPDPE) and deltorphin II (selective delta opioid agonists), and U-50,488H (selective kappa opioid agonist) in the hot-plate and tail-immersion tests. In contrast, the stress-induced opioid mediated responses were modified in CB1 mutants. Indeed, these mutants did not exhibit antinociception following a forced swim in water at 34 degrees C and presented a decrease in the immobility induced by the previous exposure to electric footshock. However, the antinociception induced by a forced swim in water at 10 degrees C was preserved in CB1 mutants. These results indicate that CB1 receptors are not involved in the antinociceptive responses to exogenous opioids, but that a physiological interaction between the opioid and cannabinoid systems is necessary to allow the development of opioid-mediated responses to stress.
Divergence caching in client-server architectures (2002)

Proposes a new mechanism, divergence caching, for reducing access and communication charges in accessing online database servers. The objective is achieved by allowing tolerant read requests, namely requests that can be satisfied by out-of-date data. We propose two algorithms based on divergence caching-static and dynamic. The first is appropriate when the access pattern to an object in the database is fixed and known, and the latter is appropriate in other cases. We analyze these algorithms in the worst case and the expected case.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
How Task Types and User Experiences Affect Information-Seeking Behavior on the Web: Using Eye-tracking and Client-side Search Logs (2009)

We investigated what influence task type and user experience had on information-seeking behaviors on the Web by using screen-capture logs and eye-movement data. Five graduate students in library and information science and eleven undergraduate students with other majors performed two dierent Web searches, a report-writing and a tripplanning task, and their think-aloud protocols, behaviors, and eye movements were recorded. Analyses of the screencapture logs and eye-movement data revealed that the task type and user experience aected the participants’ informationseeking behaviors.
The microenvironment of injured and regenerating peripheral nerves (2000)

Local events in the milieu of injured peripheral nerve trunks may have an important influence on the likelihood of regenerative success or the development of neuropathic pain. Injury-related changes in the microcirculation of this milieu have provided some evidence that axonal endbulbs, structures that form at the proximal end of transected axons, dump peptides and other molecules into the injury milieu where they may exert local actions, including those on microvessels. During a later phase of nerve repair, macrophage influx and pancellular proliferative events appear to develop in a coordinated fashion. Nitric oxide is probably an important and prominent player in the injured nerve trunk, both at early and later stages of the repair process. A better understanding of the injured peripheral nerve microenvironment may allow therapeutic approaches that can enhance regeneration and diminish pain.
An Efficient NIZK Scheme for Privacy-Preserving Transactions Over Account-Model Blockchain (2020)

We introduce the abstract framework of decentralized smart contracts system with balance and transaction amount hiding property over account-model blockchain. To build a concrete system with such properties, we utilize a homomorphic public-key encryption scheme and construct a highly efficient non-interactive zero knowledge (NIZK) argument based upon the encryption scheme to ensure the validity of the transactions. Our NIZK scheme is perfect zero knowledge in the common reference string model, while its soundness holds in the random oracle model. Compared to previous similar constructions, our proposed NIZK argument dramatically improves the time efficiency in generating a proof, at the cost of relatively longer proof size.
Independent evaluation of an in‐house brachytherapy treatment planning system using simulation, measurement and calculation methods (2012)

Accuracy of treatment planning systems may significantly influence the efficacy of brachytherapy. The purpose of this work is a detailed, varied and independent evaluation of an in-house brachytherapy treatment planning software called STPS. Operational accuracy of STPS was investigated. Geometric tests were performed to validate entry and reconstruction of positional information from scanned orthogonal films. MCNP4C Monte Carlo code and TLDs were used for simulation and experimental measurement, respectively. STPS data were also compared with those from a commercial planning system (Nucletron PLATO). Discrepancy values between MCNP and STPS data and also those of PLATO and STPS at Manchester system dose prescription points (AL and AR) of tandem and ovoid configurations were 2.5% ± 0.5% and 5.4% ± 0.4%, respectively. Similar results were achieved for other investigated configurations. Observed discrepancies between MCNP and STPS at the dose prescription point and at 1 cm from the tip of the vaginal applicator were 4.5% and 25.6% respectively, while the discrepancy between the STPS and PLATO data at those points was 2.3%. The software showed submillimeter accuracy in its geometrical reconstructions. In terms of calculation accuracy, similar to PLATO, as attenuation of the sources and applicator body is not considered, dose was overestimated at the tip of the applicator, but based on the available criteria, dose accuracy at most points were acceptable. Our results confirm STPS's geometrical and operational reliability, and show that its dose computation accuracy is comparable to an established commercial TPS using the same algorithm.
A Novel Steering System for a Space-Saving 4WS4WD Electric Vehicle: Design, Modeling, and Road Tests (2016)

In this paper, we present a steering system for a space-saving four-wheel steering and four-wheel drive (4WS4WD) electric vehicle (EV) with higher maneuverability and flexibility. The proposed system consists of three main parts, namely, an improved two-front-wheel steering (2FWS) mechanism, an omnidirectional independent steering (OIS) mechanism integrated with steer-by-wire, and a control strategy for the space-saving steering system of an EV. First, the 2FWS mechanism of the proposed 4WS4WD EV is designed to control the front wheels via the redesigned steering system when the vehicle is traveling at high speeds. Second, a retrofitted OIS mechanism is proposed to achieve an angle range of -35° ~ +90°, which is a solid basis for zero radius turning (ZRT) and lateral parking (LP) motion. The driver can control the OIS to turn the four wheels independently, which is assisted by steer-by-wire technologies. Finally, the control strategy for the space-saving steering system of the EV is redefined for the integrated 2FWS and OIS, which can easily handle the EV for high-speed driving or high-maneuverability turning, such as ZRT and LP motion. This system was field tested on a homemade 4WS4WD EV, and the final system simulation and performance evaluation demonstrated the validity of the proposed steering system for the space-saving 4WS4WD EV.
Inverter Electro-Thermal Modelling. (2015)

Abstract not provided.