gebhart/patrepeval huggingface dataset:
Diffraction analysis of bulk diffusers for projection-screen applications (1985)

A method of analyzing bulk diffusers based on diffraction theory is developed. Bulk diffusers are often used to diffuse the incident light in projection screens. They are modeled as glass spheres randomlyh suspended throughout a plastic substrate. The theory accounts for a distribution of sphere diameters. The method of analysis and results are presented. With this method of analysis, bulk diffusers can be designed with optimal optical performance.
Purification and characterization of rat kidney UDP-N-acetylglucosamine: alpha-6-D-mannoside beta-1,6-N-acetylglucosaminyltransferase. (1992)

In order to investigate the molecular mechanism of the specific increase of UDP-N-acetylglucosamine:alpha-6-D-mannoside beta-1,6-N-acetylglucosaminyltransferase (GlcNAcT-V, EC 2.4.1.155) activity after viral or oncogenic transformation, we have purified the enzyme from a Triton X-100 extract of rat kidney acetone powder. GlcNAcT-V was purified by sequential affinity chromatography using first UDP-hexanolamine-agarose and then a synthetic oligosaccharide inhibitor-agarose column. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis of the purified enzyme revealed two major bands at apparent molecular masses of 69 and 75 kDa. The enzyme was recovered in a 26% final yield with a 450,000-fold increase in specific activity to a Vmax of 18.8 mumols/(mg.min). Enzyme activity was stabilized and enhanced by the addition of 20% glycerol, 0.5 mg/ml IgG, and 0.2 M NaCl. The optimal ranges of pH and Triton X-100 concentrations for enzyme activity were 6.5-7.0 and 1.0-1.5%, respectively. The divalent cations, Mn2+, Ca2+, and Mg2+, were each found to have a negligible (less than 10%) effect on activity; moreover, the enzyme was fully active in the presence of 20 mM EDTA. The Km value of the purified enzyme toward a synthetic trisaccharide acceptor was 90 microM, and the Ki value toward a synthetic active site inhibitor was 140 microM.
Aptamer-Based Therapeutic Approaches to Target Cancer Stem Cells (2017)

Cancer stem cells (CSCs) are believed to be a principal cellular source for tumour progression and therapeutic drug resistance as they are capable of self-renewal and can differentiate into cancer cells. Importantly, CSCs acquire the ability to evade the killing effects of cytotoxic agents through changes at the genetic, epigenetic and micro-environment levels. Therefore, therapeutic strategies targeting CSCs hold great potential as an avenue for cancer treatment. Aptamers or "chemical antibodies" are a group of single-stranded nucleic acid (DNA or RNA) oligonucleotides with distinctive properties such as smaller size, lower toxicity and less immunogenicity compared to conventional antibodies. They have been frequently used to deliver therapeutic payloads to cancer cells and have achieved encouraging anti-tumour effects. This review discusses progress in CSC evolution theory and the role of aptamers to target CSCs for cancer treatment. Challenges of aptamer-mediated CSC targeting approaches are also discussed.
3-D micromachined hemispherical shell resonators with integrated capacitive transducers (2012)

We present a self-aligned fabrication method developed for three-dimensional (3-D) microscale hemispherical shell resonators with integrated capacitive transducers and a center post for electrical access to the shell. The self-aligned process preserves the axisymmetry for robust, balanced resonators that can potentially reach very high-Q due to suppressed anchor loss. High-Q operation of a thin polycrystalline silicon shell resonator is verified by exciting devices capacitively into a breathing resonance mode, with measured Q of 8,000 at 412 kHz in vacuum. This process can be further optimized to batch-fabricate micro-hemispherical resonator gyroscopes for portable inertial navigation.
Ultrasensitive Humidity Detection Using Metal–Organic Framework-Coated Microsensors (2012)

The use of metal-organic framework (MOF) thin films to detect water vapor across a wide concentration range is demonstrated using MOF-functionalized quartz surface acoustic wave (SAW) sensors. A range of 3-14,800 ppmv was obtained with thin films of the MOF Cu(3)(benzenetricarboxylate)(2) (Cu-BTC) deposited by an automated layer-by-layer method. Devices coated by a manual technique demonstrated sensitivity from 0.28 to 14,800 ppmv, the limit of our test system. This exceeds the sensitivity of many commercially available sensors. Cu-BTC layers were covalently bonded directly to the silicon oxide surface, allowing devices to be heated beyond 100 °C to desorb water adsorbed in the pores without decomposition, thereby regenerating the sensors. Sensor response as a function of coating thickness was evaluated, showing that the SAW sensor response is bounded by maximum and minimum layer thicknesses. Computer simulation of H(2)O uptake shows a multistep adsorption isotherm defined by initial adsorption at open Cu-sites, followed by pore-filling and finally full saturation. Modeling and experimental results are consistent. Calculated uptake values suggest an efficient adsorption of H(2)O by Cu-BTC. These results provide the first convincing evidence that MOF functionalization of compact sensing technologies such as SAW devices and microcantilevers can compete with state-of-the art devices.
MicroRNAs in cerebrospinal fluid identify glioblastoma and metastatic brain cancers and reflect disease activity (2012)

An accurate, nonsurgical diagnostic test for brain tumors is currently unavailable, and the methods of monitoring disease progression are not fully reliable. MicroRNA profiling of biological fluids has recently emerged as a diagnostic tool for several pathologic conditions. Here we tested whether microRNA profiling of cerebrospinal fluid (CSF) enables detection of glioblastoma, discrimination between glioblastoma and metastatic brain tumors, and reflects disease activity. We determined CSF levels of several cancer-associated microRNAs for 118 patients diagnosed with different types of brain cancers and nonneoplastic neuropathologies by quantitative reverse transcription PCR analysis. The levels of miR-10b and miR-21 are found significantly increased in the CSF of patients with glioblastoma and brain metastasis of breast and lung cancer, compared with tumors in remission and a variety of nonneoplastic conditions. Members of the miR-200 family are highly elevated in the CSF of patients with brain metastases but not with any other pathologic conditions, allowing discrimination between glioblastoma and metastatic brain tumors. Quantification of as few as 7 microRNAs in CSF enables differential recognition of glioblastoma and metastatic brain cancer using computational machine learning tools (Support Vector Machine) with high accuracy (91%-99%) on a test set of samples. Furthermore, we show that disease activity and treatment response can be monitored by longitudinal microRNA profiles in the CSF of glioblastoma and non-small cell lung carcinoma patients. This study demonstrates that microRNA-based detection of brain malignancies can be reliably performed and that microRNAs in CSF can serve as biomarkers of treatment response in brain cancers.
A frequency diversity pulse-pair algorithm for extending Doppler radar velocity Nyquist range (2016)

Millimeter wave radars have been widely used for atmospheric remote sensing and tracking hard-targets from airborne platforms. For these radars, the product of the unambiguous range and Doppler velocity is limited by the radar wavelength. This work focuses on a novel method to extend the Nyquist rate of millemeter radars, which uses frequency diversity pulse-pairs for Doppler phase estimation. Two short pulses with center-frequencies of f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sub> followed by f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> are transmitted during the first pulse repetition interval (PRI). During the next PRI, the pulses transmitted are in the order f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> followed by f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sub> respectively. There are two mechanisms for error reduction. First, the "beat" phases of the f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sub> /f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> and f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> /f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sub> pairs cancel out in the expected value sense. Second, since the f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sub> /f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> and f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> /f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sub> phase estimates are highly anti-correlated, the sum of the two phase estimates has a much smaller variance than the individual phase estimates. Based on Monte-Carlo simulations, the feasibility of this method is demonstrated herein. Ongoing data analysis is discussed.
Homogeneous DNA Hybridization Assay by Using Europium Luminescence Energy Transfer (2000)

Homogeneous DNA hybridization assay based on luminescence resonance energy transfer (LRET) from a tetradentate beta-diketonate europium chelate, 4,4'-bis(1' ',1' ',1' ',2' ',2' ',3' ',3' '-heptafluoro-4' ',6' '-hexanedion-6' '-yl)-chlorosulfo-o-terphenyl (BHHCT)-Eu(3+) (lambda(ex) = 340 nm and lambda(em) = 615 nm), to an organic dye, Cy5 (lambda(ex) = 643 nm and lambda(em) = 669 nm) has been developed, in which two DNA probes whose sequences comprises the whole complementary strand to the target DNA, are used; one probe having a biotin label on the 3'-terminus and the other a Cy5 label on the 5'-terminus. After hybridization, streptavidin labeled with BHHCT-Eu(3+) was added to the hybridization solution, and in the presence of the target DNA, the sensitized emission of Cy5 was observed when the hybridized complex was irradiated at 340 nm. In the absence of the target DNA, no emission was observed from Cy5.
Silicon Nitride/Silicon Carbide Nanocomposites from Polymer Precursor (2008)

Nanocomposites of silicon nitride and silicon carbide were processed by different routes based on polymer precursor pyrolysis. Electric field assisted sintering (EFAS) can lead to either micro-nano or nano-nano composites, depending on the amount of oxide additive. In-situ pyrolysis/consolidation produced nano-nanocomposites with bi-crystal boundaries free of glassy grain boundary phases, while small amount of residual amorphous Si–C–N phase is retained at triple junctions. High pressure sintering results in a diversity of microstructures, from amorphous to nanocrystalline. The details of the microstructures were studied by high-resolution transmission electron microscopy (HRTEM).
Adaptive Grouped Physical Layer Multicast and Beamforming for Massive MIMO (2020)

In this paper, we consider an adaptive grouped physical layer multicasting for large-scale multi-antenna wireless systems in which a set of users are divided into several groups and each user group are assigned with a unique beamforming vector for multicast transmissions on the orthogonal resources. Based on the adaptive grouped multicast framework, we consider the joint design of user grouping and multicast beamforming adapted to the user channels. Two design objectives are studied, i.e., the average-rate maximization and the max-min fairness. We propose an iterative user grouping and beamforming design method for both optimization objectives. For iterative user grouping, we present a method for selecting better initial grouping centers. Moreover, to overcome the issue of converging to a local optimum for the iterative approach, we propose a novel enhancement scheme via user grouping perturbation, which performs very close to the exhaustive grouping search. Simulation results demonstrate the efficacy of the proposed designs.
Liquid Crystal Tunable Filter Raman Chemical Imaging (1996)

A Lyot-type liquid crystal tunable filter (LCTF) suitable for high-definition Raman chemical imaging has been developed. The LCTF has been incorporated into an efficient Raman imaging system that provides significant performance advantages relative to any previous approach to Raman microscopy. The LCTF and associated optical path is physically compact, which accommodates integration of the LCTF within an infinity-corrected optical microscope. The LCTF simultaneously provides diffraction-limited spatial resolution and 7.6-cm-1 spectral bandpass across the full free spectral range of the imaging spectrometer. The LCTF Raman microscope successfully integrates, in a facile manner, the utility of optical microscopy and the analytical capabilities of Raman spectroscopy. In this paper the LCTF Raman imaging system is described in detail, as well as results of initial studies of polymer and corrosion product model systems.
Frequency stabilized coherent Brillouin random fiber laser: theory and experiments (2013)

A coherent random fiber laser based on stimulated Brillouin scattering as gain and Rayleigh scattering as distributed feedback mirror was constructed. Its frequency is stabilized by a high finesse narrow-band Fabry-Perot interferometer (FPI) to select lasing frequency within the gain bandwidth. The light confinement within single-mode fiber enhances largely the random lasing directionality, which enables a high-quality coherent random lasing in the weak scattering region by using a milliwatt continuous-wave pump source. The FPI in the laser configuration acts as a frequency selection on the Rayleigh feedback light, and thus the random lasing frequency was locked at one of its transmission peaks giving a relative frequency fluctuation of ~2.5 × 10(-11) at 100 s. The measured frequency jitter is within ~~ ± 20 kHz over 3 hours, 3 dB linewidth is ~50 Hz and frequency noise is ~20 mHz/Hz(1/2) at 10 kHz.
Real-time performance modeling for adaptive software systems with multi-class workload (2009)

Modern, adaptive software systems must often adjust or reconfigure their architecture in order to respond to continuous changes in their execution environment. Efficient autonomic control in such systems is highly dependent on the accuracy of their representative performance model. In this paper, we are concerned with real-time estimation of a performance model for adaptive software systems that process multiple classes of transactional workload. Based on an open queueing network model and an Extended Kalman Filter (EKF), experiments in this work show that: (1) the model parameter estimates converge to the actual value very slowly when the variation in incoming workload is very low, (2) the estimates fail to converge quickly to the new value when there is a step-change caused by adaptive reconfiguration of the actual software parameters. We therefore propose a modified EKF design in which the measurement model is augmented with a set of constraints based on past measurement values. Experiments demonstrate the effectiveness of our approach that leads to significant improvement in convergence in the two cases.
A Carrier-Based PWM Scheme for Neutral-Point Voltage Balancing in Three-Level Inverters (2005)

A significant problem with neutral-point-clamped three-level inverters is the fluctuation in the neutral-point voltage. In this paper, a capacitor voltage balancing technique for carrier-based three-level pulsewidth modulation (PWM) is developed, with improved voltage control capability at high modulation index. The method incorporates a novel scheme that requires measurements of only the motor currents and capacitor voltages to implement voltage balancing control, and does not need to determine the direction of power flow between the inverter and the motor.
Recent progress in manufacturing technology for aromatic aldehydes. (1991)

Current research and development trends in manufacturing technology for aromatic aldehydes are reviewed including oxidation, halogenation, formylation and reduction methods. In addition to the subject, a new technology of direct hydrogenation reaction of carboxylic acids with molecular hydrogen, which is commercialized recently using authors' catalyst, is briefly summarized.
Clustering potential phishing websites using DeepMD5 (2012)

NCT03340259.
Secondary radix recodings for higher radix multipliers (2005)

For progressively higher radices, the reduction in partial products obtained by the well-known modified Booth multiplier recoding is offset by the need to precompute a rapidly increasing store of odd multiples of the multiplicand as inputs to each partial product generator (PPG). We propose secondary radix multiplier recoding schemes reducing the number of odd multiples required in the store for very high radix recodings (e.g., radix 2/sup r/ for 5 /spl les/ r /spl les/ 16). The proposed recoding schemes allow reduction of the number of partial products in the implementation by factors between and beyond the reduction factors of 2, 3, and 4 that can be achieved by traditional Booth recodings to radices 4, 8, and 16, respectively. We develop the theory of these recodings and provide methodology for secondary radix selection. Finally, we summarize latency and cost evaluations of selected implementations indicating potential cost and performance/cost advantages for practical operand sizes.
Thin film resonator having stacked acoustic reflecting impedance matching layers and method (1995)

First Page
Specialty high bandwidth multimode fiber for optical interconnection (2009)

In this paper, we review special high bandwidth multimode fiber and their role in upgrade path of optical interconnection to 40Gbps and 100Gbps in green data centers and high performance computing.
Device for adjusting a movable electroacoustic sound transducer (1985)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Manfred Tasto, Michael Kuhn, Herbert Piotrowski, Horst Tomaschewski, Rudolf Geppert, Hermann Ney; Device for adjusting a movable electroacoustic sound transducer. J. Acoust. Soc. Am. 1 February 1985; 77 (2): 784. https://doi.org/10.1121/1.392208 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAcoustical Society of AmericaThe Journal of the Acoustical Society of America Search Advanced Search |Citation Search
Regenerative process for desulfurization of high temperature combustion and fuel gases. Progress report No. 15, January 1-March 31, 1980 (1980)

A new regenerative sorbent process for desulfurizing fluidized-bed combustion gases is presented. The sorbent was developed by Brookhaven National Laboratory and is prepared from commercial silicate bearing portland cement. The chemical reactions and mechanical procedures involved in preparing the sorbent, in desulfurizing the flue gas, in regenerating the spent sorbent, and in producing elemental sulfur from the regenerator product gas are discussed. The performance of natural limestone sorbents is compared with that of portland cement pellets in each of the above operations. Conceptual engineering designs and cost data for atmospheric fluidized-bed (AFB) power generation plants using limestone and portland cement sorbents are also presented. Cost and limestone process data were obtained from US Government publication PRS-23 EPA-600/7-77-126 which was prepared by General Electric, Bechtel and Foster Wheeler Energy Corporations and the Tennessee Valley Authority. The results of our analyses indicate that the cost of generating electricity by a regenerative portland cement sorbent plant would be about 12% lower than for once-through limestone AFB plants, about 17% lower than conventional power plants using wet limestone scrubbers and about 12% lower than regenerative magnesium oxide (MgO) scrubber plants.
Organometal halide perovskite thin films and solar cells by vapor deposition (2015)

Vapor based methods provide a promising alternative way to fabricate organometal halide perovskite solar cells.
Parallel CABAC for low power video coding (2008)

With the growing presence of high definition video content on battery-operated handheld devices such as camera phones, digital still cameras, digital camcorders, and personal media players, it is becoming ever more important that video compression be power efficient. A popular form of entropy coding called Context-Based Adaptive Binary Arithmetic Coding (CABAC) provides high coding efficiency but has limited throughput. This can lead to high operating frequencies resulting in high power dissipation. This paper presents a novel parallel CABAC scheme which enables a throughput increase of N-fold (depending on the degree parallelism), reducing the frequency requirement and expected power consumption of the coding engine. Experiments show that this new scheme (with N=2) can deliver ∼2x throughput improvement at a cost of 0.76% average increase in bit-rate or equivalently a decrease in average PSNR of 0.025dB on five 720p resolution video clips when compared with H.264/AVC.
A 24GHz phased-array transmitter in 0.18μm CMOS (2005)

A fully integrated 4-element phased-array transmitter at 24 GHz with on-chip PAs is implemented in a 0.18 /spl mu/m CMOS process. It has a beam-forming resolution of 10/spl deg/, a peak-to-null ratio of 23 dB, and isolation between paths of 28 dB. Each CMOS PA can deliver up to +14 dBm into a 50 /spl Omega/ load. The transmitter supports a 500 Mb/s QPSK signal and has a bandwidth in excess of 400 MHz. The die size is 6.8/spl times/2.1 mm/sup 2/ and the complete 4-element transmitter, including the 4 on-chip PAs, draws 788 mA from a 2.5 V supply.
N6-Substituted adenosine receptor agonists: potential antihypertensive agents (1991)

Adenosine is known to exert a wide range of pharmacological effects including hypotension. This effect of adenosine suggested that modified analogues of adenosine might provide useful antihypertensive agents. Thus, we prepared a series of novel N6-benzocycloalkyladenosines and studied their receptor binding and antihypertensive activity. The structure-activity relationship study shows that the adenosine analogues having the hydrophobic phenyl moiety one carbon away from the C6-nitrogen have modest affinity and selectivity for the A1 receptor, whereas those with the phenyl moiety two carbons away from the C6-nitrogen have excellent affinity and selectivity for the A1 receptor. Many of these analogues showed excellent antihypertensive activity with a wide range of effects on heart rate. There is no direct correlation between the receptor binding affinities and antihypertensive activity; however, it is more closely associated with A1 than A2 affinity. The bradycardic effect of these agonists seems to be due to the A1 affinity. From this set, compound 3 was further evaluated in secondary antihypertensive screens. It lowered the blood pressure dose dependently with effects lasting for over 20 h following administration of a 30 mg/kg dose. Compound 3 was also effective in lowering blood pressure in a renal hypertensive rat model. Thus, appropriately modified N6-substituted adenosines represent a novel class of antihypertensive agents.