gebhart/patrepeval huggingface dataset:
Reduced rank formulation for increased computational efficiency in medical ultrasound model-based beamforming (2008)

Recently, we have developed a model-based adaptive beamforming algorithm, entitled dTONE, which significantly increases both image contrast and resolution by conducting a global optimization based on a model of a sparse set of hypothetical source locations. Due to the global nature of this optimization, a single bright source from an un-modeled location can cause significant degradation of the resulting image. As a result, the entire space from which signal may be received must be finely sampled, requiring a model of very large scale and computational complexity. We have developed a method that uses a reduced rank formulation of a subset of the hypothetical source locations to reduce the computational complexity of dTONE by several orders of magnitude with minimal degradation in image quality. Computation times were reduced by anywhere from 3.7 to 18.3 times while maintaining an image contrast and resolution far superior to that of conventional beamforming.
Purification of the Recombinant Adenovirus by Cesium Chloride Gradient Centrifugation (2019)

Cesium chloride gradient centrifugation is the most widely used method for purification of recombinant adenovirus. This protocol describes the entire process, from the preparation and clarification of crude viral lysate to the formulation and storage of purified virus.
Contemporary Surgical Treatment of Advanced-Stage Melanoma (2004)

Our results demonstrate the benefit of surgical resection for advanced-stage melanoma. Patients with limited sites and numbers of metastases should be considered for curative resection regardless of the location of the disease.
Interactive Slave Operations: Muslim-Christian Jewish Contracts in Thirteenth-Century Barcelona (1999)

Abstract Medieval Mediterranean Spain saw routine interaction between all three ethnoreligious populations, most of it random and undocumented. Slave purchases constituted one such tri-ethnic situation, as exemplified in the four charters transcribed and contextualized here, from the cathedral archives of Barcelona in 1252, 1275, 1286, and 1290. Each operation moved a slave from one public and private cultural ambience to another; each involved women; each was a local, short-term transaction; and each illustrates the generalities available in our slave data base. Family, social class, economic framework, and legal context can be clarified for each transaction in turn. As corsairs scoured the seas, especially for women slaves to service the century's new patrician life-style, a Muslim slave community populated perhaps 21 percent of Barcelona households, part of a mass population interchange between Islam and Christendom, facilitated by Jewish entrepreneurs whose Hebrew signatures are on each of these early and therefore rare slave parchments.
First nationwide study regarding ceftriaxone resistance and molecular epidemiology of<i>Neisseria gonorrhoeae</i>in China (2015)

In China, ceftriaxone and spectinomycin can continue to be recommended for gonorrhoea treatment, with the possible exception of Hainan and Sichuan provinces where ceftriaxone resistance exceeded 5% and AMR surveillance needs to be strengthened. Molecular approaches including genotyping and AMR determinant analysis can be valuable to supplement and enhance conventional surveillance of gonococcal AMR in China.
Electrospray ionization mass spectroscopic analysis of human erythrocyte plasma membrane phospholipids. (1994)

Electrospray ionization mass spectrometry (ESI-MS) was utilized for the structural determination and quantitative analysis of individual phospholipid molecular species from subpicomole amounts of human erythrocyte plasma membrane phospholipids. The sensitivity of ESI-MS was 2-3 orders of magnitude greater than that achievable with fast-atom bombardment mass spectrometry (FAB-MS). Phospholipid structure determination and quantitative analysis with ESI-MS can be performed directly from chloroform extracts of biologic samples, obviating the need for prior chromatographic separation of phospholipid classes which has been necessary in FAB-MS phospholipid analyses. Furthermore, ESI-MS is uncomplicated by differential fragmentation of molecular ions and idiosyncratic surface desorption, allowing the quantitation of phospholipids with coefficients of determination (r2) > 0.99 and accuracies > 95%. More than 50 human erythrocyte plasma membrane phospholipid constituents were identified by direct ESI-MS analysis of chloroform extracts of plasma membranes derived from the equivalent of < 1 microliter of whole blood. The major ethanolamine glycerophospholipid subclass in erythrocyte plasma membranes was plasmenylethanolamine that was highly enriched in polyunsaturated fatty acids at the sn-2 position. Collectively, these results demonstrate that ESI-MS of phospholipids is an enabling strategy for the direct structural determination and quantitative analysis of subpicomole amounts of phospholipids from biologic samples.
A Systematic Review on the Effects of Botanicals on Skeletal Muscle Health in Order to Prevent Sarcopenia (2016)

We performed a systematic review to evaluate the evidence-based medicine regarding the main botanical extracts and their nutraceutical compounds correlated to skeletal muscle health in order to identify novel strategies that effectively attenuate skeletal muscle loss and enhance muscle function and to improve the quality of life of older subjects. This review contains all eligible studies from 2010 to 2015 and included 57 publications. We focused our attention on effects of botanical extracts on growth and health of muscle and divided these effects into five categories: anti-inflammation, muscle damage prevention, antifatigue, muscle atrophy prevention, and muscle regeneration and differentiation.
From the editor: engineering our way (2003)

Presents the editorial for this issue of the publication.
Nonlinear Quantum Mechanics Implies Polynomial-Time Solution for<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mi mathvariant="italic">NP</mml:mi></mml:math>-Complete and #<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mi mathvariant="italic">P</mml:mi></mml:math>Problems (1998)

If quantum states exhibit small nonlinearities during time evolution, then quantum computers can be used to solve $\mathrm{NP}$-complete and # $P$ problems in polynomial time. We provide algorithms that solve $\mathrm{NP}$-complete and # $P$ oracle problems by exploiting nonlinear quantum logic gates. Using the Weinberg model as a simple example, the explicit construction of these gates is derived from the underlying physics. Nonlinear quantum algorithms are also presented using Polchinski type nonlinearities which do not allow for superluminal communication.
Recursive temporal namespaces (2008)

Recursive temporal (RT) namespaces extend spatial namespaces such as IP with the notion of a nested time interval. RT namespace is an architectural approach to dealing with the uncertainty associated with changes to distribution, syntax or semantics of large-scale namespaces that are associated with high cost and probability of failure. We discuss the abstract design issues associated with RT namespaces and two existing approaches that are special cases of the general design. We also propose a variant of IP based on RT namespaces that supports open-ended evolution.
Synapses and Memory Storage (2012)

The synapse is the functional unit of the brain. During the last several decades we have acquired a great deal of information on its structure, molecular components, and physiological function. It is clear that synapses are morphologically and molecularly diverse and that this diversity is recruited to different functions. One of the most intriguing findings is that the size of the synaptic response in not invariant, but can be altered by a variety of homo- and heterosynaptic factors such as past patterns of use or modulatory neurotransmitters. Perhaps the most difficult challenge in neuroscience is to design experiments that reveal how these basic building blocks of the brain are put together and how they are regulated to mediate the information flow through neural circuits that is necessary to produce complex behaviors and store memories. In this review we will focus on studies that attempt to uncover the role of synaptic plasticity in the regulation of whole-animal behavior by learning and memory.
Neutron radiography technique and its application on research of concrete materials (2009)

The principles and basic equipments of neutron radiography have been introduced;this technique has been utilized to detect and study concrete materials.The results indicate that,neutron radiography could be used to directly detect the crack inside the reinforced concrete;it could also make the process of water penetration into concrete visually.Based on the neutron radiographies,traditional model of water penetration has been modified.At the beginning of water penetration the coefficient of penetration was a constant;while the contact time with water went up to four hours,the coefficient decreased according to an exponential function.
Beef Quality Assurance “Down Under” (2015)

Australia exports approximately 60 percent of its beef production and New Zealand exports 85 percent. Because they depend on a diverse set of export customers, these countries are developing quality assurance programs that differentiate their beef in domestic and global markets and assure that the product is safe and meets individual customers’ needs. Whereas most U.S. producers think of quality in terms of USDA grades (Prime, Choice, Select), Australian and New Zealand supply chains strive to meet the mark of quality as defined by their customers. To break out of the commodity market, supply chains in the two countries typically provide additional information about their products and strive to differentiate them from those of their competitors.
Bleached pigment activates transduction in salamander cones. (1995)

We have used suction electrode recording together with rapid steps into 0.5 mM IBMX solution to investigate changes in guanylyl cyclase velocity produced by pigment bleaching in isolated cones of the salamander Ambystoma tigrinum. Both backgrounds and bleaches accelerate the time course of current increase during steps into IBMX. We interpret this as evidence that the velocity of the guanylyl cyclase is increased in background light or after bleaching. Our results indicate that cyclase velocity increases nearly linearly with increasing percent pigment bleached but nonlinearly (and may saturate) with increasing back-ground intensity. In cones (as previously demonstrated for rods), light-activated pigment and bleached pigment appear to have somewhat different effects on the transduction cascade. The effect of bleaching on cyclase rate is maintained for at least 15-20 min after the light is removed, much longer than is required after a bleach for circulating current and sensitivity to stabilize in an isolated cone. The effect on the cyclase rate can be completely reversed by treatment with liposomes containing 11-cis retinal. The effects of bleaching can also be partially reversed by beta-ionone, an analogue of the chromophore 11-cis-retinal which does not form a covalent attachment to opsin. Perfusion of a bleached cone with beta-ionone produces a rapid increase in circulating current and sensitivity, which rapidly reverses when the beta-ionone is removed. Perfusion with beta-ionone also causes a partial reversal of the bleach-induced acceleration of cyclase velocity. We conclude that bleaching produces an "equivalent background" excitation of the transduction cascade in cones, perhaps by a mechanism similar to that in rods.
Sputtered indium-tin oxide/cadmium telluride junctions and cadmium telluride surfaces (1980)

The properties of indium-tin oxide (ITO)/CdTe junction solar cells prepared by rf sputtering of ITO on P-doped CdTe single-crystal substrates have been investigated through measurements of the electrical and photovoltaic properties of ITO/CdTe and In/CdTe junctions, and of electron beam induced currents (EBIC) in ITO/CdTe junctions. In addition, surface properties of CdTe related to the sputtering process were investigated as a function of sputter etching and thermal oxidation using the techniques of surface photovoltage and photoluminescence. ITO/CdTe cells prepared by this sputtering method consist of an n+-ITO/n-CdTe/p-CdTe buried homojunction with about a 1-μm-thick n-type CdTe layer formed by heating of the surface of the CdTe during sputtering. Solar efficiencies up to 8% have been observed with V0c=0.82 V and Jsc=14.5 mA/cm2. The chief degradation mechanism involves a decrease in V0c with a transformation of the buried homojunction structure to an actual ITO/CdTe heterojunction.
Comparison between atomic-layer-deposited HfO2 films using O3 or H2O oxidant and Hf[N(CH3)2]4 precursor (2004)

The dielectric properties of HfO2 thin films, which were deposited on Si wafers by an atomic layer deposition (ALD) technique at a wafer temperature of 300 °C using a N-containing, tetrakis dimethylamido hafnium precursor (Hf[N(CH3)2]4), were highly improved by adopting O3 as the oxidant during the ALD instead of H2O. The films contained a much smaller carbon impurity concentration and were of more amorphous nature compared to the films grown using H2O as oxidant. Temperature-dependent leakage current analysis showed that the films grown using O3 as oxidant had a higher interfacial potential barrier for tunneling and the leakage current densities of the as-deposited film were three orders of magnitude smaller than that of the films grown using H2O. The dielectric constant of the HfO2 film was 24.4 and the leakage current density was 1.6×10−7A∕cm2 when the capacitance equivalent thickness was 1.49 nm.
Good Vibrations: Cross-frequency Coupling in the Human Nucleus Accumbens during Reward Processing (2008)

The nucleus accumbens is critical for reward-guided learning and decision-making. It is thought to "gate" the flow of a diverse range of information (e.g., rewarding, aversive, and novel events) from limbic afferents to basal ganglia outputs. Gating and information encoding may be achieved via cross-frequency coupling, in which bursts of high-frequency activity occur preferentially during specific phases of slower oscillations. We examined whether the human nucleus accumbens engages such a mechanism by recording electrophysiological activity directly from the accumbens of human patients undergoing deep brain stimulation surgery. Oscillatory activity in the gamma (40-80 Hz) frequency range was synchronized with the phase of simultaneous alpha (8-12 Hz) waves. Further, losing and winning small amounts of money elicited relatively increased gamma oscillation power prior to and following alpha troughs, respectively. Gamma-alpha synchronization may reflect an electrophysiological gating mechanism in the human nucleus accumbens, and the phase differences in gamma-alpha coupling may reflect a reward information coding scheme similar to phase coding.
A Monoclonal Antibody TrkB Receptor Agonist as a Potential Therapeutic for Huntington’s Disease (2014)

Huntington's disease (HD) is a devastating, genetic neurodegenerative disease caused by a tri-nucleotide expansion in exon 1 of the huntingtin gene. HD is clinically characterized by chorea, emotional and psychiatric disturbances and cognitive deficits with later symptoms including rigidity and dementia. Pathologically, the cortico-striatal pathway is severely dysfunctional as reflected by striatal and cortical atrophy in late-stage disease. Brain-derived neurotrophic factor (BDNF) is a neuroprotective, secreted protein that binds with high affinity to the extracellular domain of the tropomyosin-receptor kinase B (TrkB) receptor promoting neuronal cell survival by activating the receptor and down-stream signaling proteins. Reduced cortical BDNF production and transport to the striatum have been implicated in HD pathogenesis; the ability to enhance TrkB signaling using a BDNF mimetic might be beneficial in disease progression, so we explored this as a therapeutic strategy for HD. Using recombinant and native assay formats, we report here the evaluation of TrkB antibodies and a panel of reported small molecule TrkB agonists, and identify the best candidate, from those tested, for in vivo proof of concept studies in transgenic HD models.
Multimeßsystem für die elektrochemische Analyse strömender Flüssigkeiten und Gase - Multiple Measurement System for the Electrochemical Analysis of Flowing Liquids and Gases (1977)

Article Multimeßsystem für die elektrochemische Analyse strömender Flüssigkeiten und Gase - Multiple Measurement System for the Electrochemical Analysis of Flowing Liquids and Gases was published on January 1, 1977 in the journal Biomedical Engineering / Biomedizinische Technik (volume 22, issue 10).
Synthesis of a New Ladder-Type Benzodi(cyclopentadithiophene) Arene with Forced Planarization Leading to an Enhanced Efficiency of Organic Photovoltaics (2012)

We have developed a new heptacyclic benzodi(cyclopentadithiophene) (BDCPDT) unit, where 3,7-positions of the central benzo[1,2-b:4,5-b′]dithiophenes (BDT) subunit are covalently rigidified with 3-positons of the two external thiophenes by two carbon bridges, forming two external CPDT rings that share two thiophene rings with the central BDT core. The distannyl-BDCPDT building block was copolymerized with 1,3-dibromo-thieno[3,4-c]pyrrole-4,6-dione (TPD) by Stille polymerization to afford a new alternating donor–acceptor copolymer PBDCPDT-TPD. The implementation of forced planarization greatly suppresses the interannular twisting to extend the effective conjugated length and preserve the interactions between the donor and acceptor segments. The device using the PBDCPDT-TPD/PC71BM (1:3 in wt%) blend processed with dimethyl sulfoxide as an additive delivered a marked PCE of 6.6% which represents a significant enhancement compared to the device using the corresponding nonfused polymer analogue with a PCE of 0.2%.
Characterization of a <i>cis</i> -Acting Sequence in the <i>pol</i> Region Required To Transfer Human Foamy Virus Vectors (1998)

To identify cis-acting elements in the foamy virus (FV) RNA pregenome, we developed a transient-vector-production system based on cotransfection of indicator gene-bearing vector and gag-pol and env expression plasmids. Two elements which were critical for vector transfer were found and mapped approximately. The first element was located in the RU5 leader and the 5' gag region (approximately up to position 650 of the viral RNA). The second element was located in an approximately 2-kb sequence in the 3' pol region. Although small 5' and 3' deletions, as well as internal deletions of the latter element, were tolerated, both elements were found to be absolutely required for vector transfer. The functional characterization of the pol region-located cis-acting element revealed that it is essential for efficient incorporation or the stability of particle-associated virion RNA. Furthermore, virions derived from a vector lacking this sequence were found to be deficient in the cleavage of the Gag protein by the Pol precursor protease. Our results suggest that during the formation of infectious virions, complex interactions between FV Gag and Pol and the viral RNA take place.
Analysing the Robustness of Surfing Circuits (2006)

Surfing is a technique for implementing high-speed digital pipelines that exploits the analog dynamics of the underlying circuits. Thus, verification must consider the analog behaviour of the design. We have presented a method for analysing the robustness of surfing circuits. We formulate noise margin analysis as a non-linear optimization problem where we find the smallest disturbance waveform that results in a qualitative change in the behavior of the circuit. We present a practical method for solving these optimization problems based on deriving a sensitivity matrix for the small-signal response of the circuit.
Chapitre 7. Quelques repères nécessaires à la construction des actions (1993)

Il est banal de dire que la mise en œuvre des actions dʹinsertion par le sport sʹest déclenchée selon une logique de coup et de prestation de services qui a parfois pu susciter une impression dʹéclatement et donner à penser que tout pouvait être fait (et son contraire) sans que les différences sensibles soient explicitement justifiées par un axe unitaire1. En ce qui concerne les OPE, le laboratoire de sociologie de
Chemotherapy‐driven dysbiosis in the intestinal microbiome (2015)

Our study identifies a severe compositional and functional imbalance in the gut microbial community associated with chemotherapy-induced GI mucositis. The functional pathways implicated in our analysis suggest potential directions for the development of intestinal microbiome-targeted interventions in cancer patients.
Base station multicoupler design for UK cellular radio systems (1987)

Intermodulation interference in a TACS cellular radio scheme can be reduced if the base station multicoupler operates at 900 MHz, with transmitter frequency spacings of 200 kHz. Such a combiner, using a high-Q cavity and a circu-lator in each branch, is described. This gives a total transmitter-transmitter isolation of 75 dB for an insertion loss of 2.5 dB.
OOPSLA distributed object management (1990)

article Free Access Share on OOPSLA distributed object management Authors: John R. Rymer Seybold Office Computing Group, Moderator Seybold Office Computing Group, ModeratorView Profile , Richard Mark Soley Vice President, Object Management Group Vice President, Object Management GroupView Profile , William Stephen Andreas Staff Software Engineer, Distributed Applications Architecture, Data General Staff Software Engineer, Distributed Applications Architecture, Data GeneralView Profile , Ian Fuller Project Manager, Distributed New Wave Application Architecture, Hewlett-Packard Project Manager, Distributed New Wave Application Architecture, Hewlett-PackardView Profile , Neal Jacobson Principal Engineer, Distributed Information Systems, Digital Equipment Corp. Principal Engineer, Distributed Information Systems, Digital Equipment Corp.View Profile , Richard A. Demers Distributed Data Management Architecture, IBM Distributed Data Management Architecture, IBMView Profile Authors Info & Claims ACM SIGPLAN NoticesVolume 25Issue 10Oct. 1990 pp 331–333https://doi.org/10.1145/97946.97985Published:01 September 1990Publication History 0citation229DownloadsMetricsTotal Citations0Total Downloads229Last 12 Months10Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Structure and magnetic properties of Bi-Zn-Fe-O amorphous films (1986)

Strong ferromagnet-like glasses have been prepared by rapidly quenching the molten mixture of antiferromagnetic BiFeO <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</inf> and ZnFe <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> O <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4</inf> and by depositing simultaneously the ionized clusters of Bi, Zn and Fe atoms in a low pressure oxygen gas atmosphere. The Curie temperature of the glasses appears at 460-510 K and the magnetization reaches about 15-20 emu/g at 10 kOe at room temperature. Based on the Mössbauer effect and EXAFS measurements, the glass is concluded to be a speromagnet consisting of magnetic spins localized on each Fe atom tetrahedrally surrounded by four 0 atoms.