gebhart/patrepeval huggingface dataset:
Development and Evaluation of a Model Predicting the Survival of <i>Escherichia coli</i> O157:H7 NCTC 12900 in Homemade Eggplant Salad at Various Temperatures, pHs, and Oregano Essential Oil Concentrations (2000)

ABSTRACT Homemade eggplant salad, a traditional Greek appetizer, was inoculated with Escherichia coli O157:H7 NCTC 12900 supplemented with different concentrations of oregano essential oil (0.0, 0.7, 1.4, and 2.1% [vol/wt]) and stored at different temperatures (0, 5, 10, and 15°C). The product's pH was adjusted to 4.0, 4.5, or 5.0 with lemon juice. For each combination of the environmental factors, the bacterial counts were modeled, using the Baranyi model, as a function of time to estimate the kinetic parameters of the pathogen. A reduction of more than 1 log unit in E. coli O157:H7 counts was observed in all cases, and the death rate depended on the pH, the storage temperature, and the essential oil concentration. Separate quadratic models were developed with natural logarithms of the shoulder period and death rate as estimated by the growth model, as a function of temperature, pH, and oregano essential oil concentrations. These were further used to predict the population of E. coli O157:H7 NCTC 12900 from other inoculated eggplant salads at random conditions of temperature, pH, and oregano oil concentration. The predicted values were compared with viable-count measurements for validation.
Sequential traitor tracing (2003)

We consider a new type of traitor tracing scheme, called sequential traitor tracing, that protects against rebroadcasting of decrypted content. Sequential traceability (TA) schemes trace all up to c traitors and remove the shortcomings of dynamic tracing schemes. We give two general constructions and show the relationship between c-TA codes and sequential tracing schemes.
PARSEME.1st : SGML for software developers (1998)

PARSEME.1ST is the first developer's guide to both SGML's practicalities and its worldview. It will tell you everything you need to build world-class SGML systems and products. Start by walking through all the basics of SGML - from the perspective of an experienced developer. Understand the structure of SGML documents and systems - and how SGML can solve a remarkable number of real-world problems. Then, get the detailed information and worked examples you need to implement practical solutions.
Design and characterization of a compact rotary Series Elastic Actuator for knee assistance during overground walking (2012)

In wearable robotics applications, actuators are required to satisfy strict constraints in terms of safety and controllability. The introduction of intrinsic compliance can help to meet both these requirements. However, the high torque and power necessary for robotic systems for gait assistance requires the use of custom elements, able to guarantee high performances with a compact and lightweight design. This paper presents a rotary Series Elastic Actuator (SEA), suitable to be used in an active orthosis for knee assistance during overground walking. The system includes a commercial flat brushless DC motor, a Harmonic Drive gear and a custom-designed torsion spring. Spring design has been optimized by means of an iterative FEM simulations-based process and can be directly connected to the output shaft, thus guaranteeing high torque fidelity. With a total weight of 1.8 kg, it is possible to directly include the actuator in the frame of a wearable orthosis for knee flexion/extension assistance. The presented design allows to obtain a large-force bandwidth of 5 Hz and to regulate output impedance in a range compatible to locomotion assistance of elderly subjects with an age-related decay of motor performances.
Synthesis and Characterization of Polymerizable Tourmaline Methacrylate (2015)

The surface modification of tourmaline powder with methacrylic anhydride was studied in this work, and the reaction process conditions were optimized according to the experimental parameters of contact angle and turbidity in liquid paraffin. The structure of the modified tourmaline was characterized by means of IR, XRD and SEM. The structural analysis indicated that methacrylic group was attached onto the surface of tourmaline by the reaction of tourmaline with methacrylic anhydride to get a polymerizable tourmaline methacrylate. The experimental results indicated that modified tourmaline presented enhanced hydrophobicity than the unmodified tourmaline. [DOI: 10.1380/ejssnt.2015.422]
A fast and practical approach to genotype phasing and imputation on a pedigree with erroneous and incomplete information (2012)

The MINIMUM-RECOMBINANT HAPLOTYPE CONFIGURATION problem (MRHC) has been highly successful in providing a sound combinatorial formulation for the important problem of genotype phasing on pedigrees. Despite several algorithmic advances that have improved the efficiency, its applicability to real data sets has been limited since it does not take into account some important phenomena such as mutations, genotyping errors, and missing data. In this work, we propose the MINIMUM-RECOMBINANT HAPLOTYPE CONFIGURATION WITH BOUNDED ERRORS problem (MRHCE), which extends the original MRHC formulation by incorporating the two most common characteristics of real data: errors and missing genotypes (including untyped individuals). We describe a practical algorithm for MRHCE that is based on a reduction to the well-known Satisfiability problem (SAT) and exploits recent advances in the constraint programming literature. An experimental analysis demonstrates the biological soundness of the phasing model and the effectiveness (on both accuracy and performance) of the algorithm under several scenarios. The analysis on real data and the comparison with state-of-the-art programs reveals that our approach couples better scalability to large and complex pedigrees with the explicit inclusion of genotyping errors into the model.
Formation of Silicon Nanowires by CVD Using Gold Catalysts at Low Temperatures (2007)

Silicon nanowires (SiNWs) on a {100} silicon wafer coated with a gold film were formed by thermal cracking of disilane at 473–573 K. The SiNWs were single-crystalline with 10–100 nm in diameter and a 〈111〉 crystal orientation. The optimum conditions for obtaining long SiNWs that are several hundred μm long include a disilane flow rate of 0.017 cm3/s, an argon gas flow rate of 0.33 cm3/s, and a total pressure of 0.67 kPa. The low-temperature formation of SiNWs was explained by lowering the melting point of Au–Si eutectic particles. Self-wiring of SiNWs between gold square dots placed 15 μm from each other was successfully conducted.
Emission polarization of roughened glass and aluminum surfaces (1996)

Ellipsometer measurements of the effective complex refractive index at a wavelength of 10.6 μm are made on a series of glass and aluminum surfaces of increasing surface roughness. The measured values are then used to calculate the degree of emission polarization and are shown to be in agreement with the experimentally determined values when depolarization is small. Comparisons are also made with calculations based on the Kirchhoff scattering theory. Both the theory and the experimental results indicate that it is the local surface slope and not the roughness magnitude that is the prime factor in determining the degree of emission polarization from the samples studied.
Current Driven Domain Wall Velocities Exceeding the Spin Angular Momentum Transfer Rate in Permalloy Nanowires (2007)

The velocity of domain walls driven by current in zero magnetic field is measured in permalloy nanowires using real-time resistance measurements. The domain wall velocity increases with increasing current density, reaching a maximum velocity of approximately 110 m/s when the current density in the nanowire reaches approximately 1.5 x 10(8) A/cm(2). Such high current driven domain wall velocities exceed the estimated rate at which spin angular momentum is transferred to the domain wall from the flow of spin polarized conduction electrons, suggesting that other driving mechanisms, such as linear momentum transfer, need to be taken into account.
GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism (2020)

Glucagon-like peptide-1 (GLP-1) is an endogenous insulinotropic peptide secreted from the gastrointestinal tract in response to food intake. It enhances pancreatic islet β-cell proliferation and glucose-dependent insulin secretion, and lowers blood glucose and food intake in patients with type 2 diabetes mellitus (T2DM). A long-acting GLP-1 receptor (GLP-1R) agonist, exendin-4 (Ex-4), is the first of this new class of antihyperglycemia drugs approved to treat T2DM. GLP-1Rs are coupled to the cAMP second messenger pathway and, along with pancreatic cells, are expressed within the nervous system of rodents and humans, where receptor activation elicits neurotrophic actions. We detected GLP-1R mRNA expression in both cultured embryonic primary cerebral cortical and ventral mesencephalic (dopaminergic) neurons. These cells are vulnerable to hypoxia- and 6-hydroxydopamine–induced cell death, respectively. We found that GLP-1 and Ex-4 conferred protection in these cells, but not in cells from Glp1r knockout (-/-) mice. Administration of Ex-4 reduced brain damage and improved functional outcome in a transient middle cerebral artery occlusion stroke model. Ex-4 treatment also protected dopaminergic neurons against degeneration, preserved dopamine levels, and improved motor function in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease (PD). Our findings demonstrate that Ex-4 can protect neurons against metabolic and oxidative insults, and they provide preclinical support for the therapeutic potential for Ex-4 in the treatment of stroke and PD.
Preparation and Application of1,3,4-Triphenyl-4,5-dihydro-1<i>H</i>-1,2,4-triazol-5-ylidene,A Stable Carbene (2003)

The title compound 1,3,4-triphenyl-4,5-dihydro-1H-1,2,4-triazol-5-ylidene has been prepared in quantitative yield from the corresponding 5-methoxytriazoline precursor by simple thermal decomposition in vacuo via α-elimination of methanol. The carbene is a stable solid in the absence of oxygen and moisture, and shows the typical reactivity of nucleophilic Wanzlick-type carbenes.
Concordance of creatine kinase-MB activity and mass. (1989)

The recent availability of monoclonal antibodies that are highly specific for creatine kinase (CK; EC 2.7.3.2) MB isoenzyme should allow for the development of rapid, sensitive, and specific assays of CK-MB mass and activity. However, the relationship between the mass concentration of CK-MB and its activity in plasma has previously been thought by some to be variable. To determine the extent to which discrepancies of potential clinical significance might arise between measurements of activity and mass in plasma, we compared CK-MB activity and concentration in 1298 samples obtained from 226 patients admitted to the cardiac-care unit. CK-MB activity concentration was determined with an immunoadsorption assay, and mass concentration was measured by an automated "sandwich" assay (Magic Lite; Ciba Corning Diagnostics). Both of these assays are based on specific monoclonal antibodies for CK-MB. Values obtained with these assays correlated well (r = 0.94). Normal and abnormal values with the two assays were concordant in 96% of the samples. In all but three instances, differences occurred late after myocardial infarction and were characterized by minimal increases as determined by one method vs values at the upper limit of normal as determined with the other. Thus, measurements of CK-MB mass and activity concentrations in plasma with assays based on these specific monoclonal antibodies are comparable for the detection or exclusion of acute myocardial infarction.
Pitfalls in horizon autopicking (2014)

Abstract Interpreters use horizon autopicking in many seismic interpretations in the modern workstation environment. When properly used and with data quality permitting this technique enables efficient and accurate tracking of horizons but is not without its pitfalls. Four common pitfalls are improper selection of the input control or seed grid, not accounting for the “directional” behavior of tracking algorithms, attempting autopicking in areas with poor reflection continuity and/or low signal-to-noise ratio, and failing to recognize elements of geology that are not suitable for autopicking.
Effects of ACE inhibition and beta-blockade on skeletal muscle fiber types in dogs with moderate heart failure (1996)

The proportion of slow-twitch, fatigue-resistant type 1 skeletal muscle (SM) fibers is often reduced in heart failure (HF), while the proportion of fatigue-sensitive type-II fibers increases. This maladaptation may be partially responsible for the exercise intolerance that characterize HF. In this study, we examined the effects of early monotherapy with the angiotensin-converting enzyme inhibor, enalapril, and the beta-blocker, metoprolol, on SM fiber type composition in 18 dogs with moderate HF produced by intracoronary microembolizations. HF dogs were randomized to 3 mo therapy with enalapril (10 mg twice daily), metoprolol (25 mg twice daily), or no treatment. Triceps muscle biopsies were obtained at baseline, before randomization, and at the end of 30 mo of therapy. Type I and type II SM fibers were differentiated by myofibrillar adenosinetriphosphatase (pH 9.4). In untreated dogs, the proportion of type I fibers was 27 +/- 1% before randomization and decreased to 23 +/- 1% (P < 0.05) at the end of 3 mo of follow up. In dogs treated with enalapril or metoprolol, the proportion of type I fibers was 30 +/- 4 and 28 +/- 2% before randomization and 33 +/- 4 and 33 +/- 1%, respectively, after 3 mo of therapy. In conclusion, in dogs with moderate HF, early therapy with enalapril or metoprolol prevents the progressive decline in the proportion of type I SM fibers.
Independent component analysis for assessing therapeutic response in vitiligo skin disorder (2009)

This paper describes an image analysis technique that objectively measures skin repigmentation for the assessment of therapeutic response in vitiligo treatments. Skin pigment disorders due to the abnormality of melanin production, such as vitiligo, cause irregular pale patches of skin. The therapeutic response to treatment is repigmentation of the skin. However the repigmentation process is very slow and is only observable after a few months of treatment. Currently, there is no objective method to assess the therapeutic response of skin pigment disorder treatment, particularly for vitiligo treatment. In this work, we apply principal component analysis followed by independent component analysis to represent digital skin images in terms of melanin and haemoglobin composition respectively. Vitiligo skin areas are identified as skin areas that lack melanin (non-melanin areas). Results obtained using the technique have been verified by dermatologists. Based on 20 patients, the proposed technique effectively monitored the progression of repigmentation over a shorter time period of six weeks and can thus be used to evaluate treatment efficacy objectively and more effectively.
Activity‐Based Pacing: Comparison of a Device Using an Accelerometer Versus a Piezoelectric Crystal (1992)

The EXCEL VR, an accelerometer-based pacemaker (AC), and the Legend, a pacemaker utilizing a piezoelectric crystal (PZ), were compared under ergometric conditions and during stair climbing to assess the appropriateness of their rate responses. The pacemakers, programmed to the manufacturers' nominal settings in order to compare different technologically based sensors under identical conditions, were strapped over subjects' left mid-pectoral region. Placement of the devices was randomized to control for positional effects. Ten healthy subjects (55-72 years) completed a graded exercise treadmill test to 80% of maximum predicted heart rate (HR). An additional group of ten subjects (50-66 years) completed exercise protocols involving bicycle ergometry and stair climbing. Throughout all tests, pacemaker pulse rates and subjects' intrinsic HR were monitored continuously. For the treadmill exercise, the average correlations between the AC and PZ pacemakers' pulse rate and HR for the group as a whole were r = 0.92 and r = 0.82, respectively. Individual subject comparisons were also made between each pacemaker rate and intrinsic HR. The mean difference from intrinsic rate was 11 ppm for the AC pacemaker and 24 ppm for the PZ pacemaker. In addition, the PZ pacemaker's maximal pulse rate was significantly lower (105 +/- 9.6 ppm) than the other two rates (AC 137 +/- 6 ppm; intrinsic HR 129 +/- 2 beats/min). Throughout the bicycle ergometry testing, the intrinsic HR was higher than the AC and PZ pacing rates. However, the AC's rate was significantly higher than the PZ's rate. When subjects ascended stairs, the intrinsic HR and AC rate were closely correlated, but the PZ rate was significantly lower.(ABSTRACT TRUNCATED AT 250 WORDS)
Electronically Driven Structural Distortions in Lithium Intercalates of the<i>n</i>= 2 Ruddlesden−Popper-Type Host Y<sub>2</sub>Ti<sub>2</sub>O<sub>5</sub>S<sub>2</sub>:  Synthesis, Structure, and Properties of Li<i><sub>x</sub></i>Y<sub>2</sub>Ti<sub>2</sub>O<sub>5</sub>S<sub>2</sub>(0 <<i>x</i>< 2) (2004)

Lithium intercalation into the oxide slabs of the cation-deficient n = 2 Ruddlesden-Popper oxysulfide Y(2)Ti(2)O(5)S(2) to produce Li(x)Y(2)Ti(2)O(5)S(2) (0 < x < 2) is described. Neutron powder diffraction measurements reveal that at low levels of lithium intercalation into Y(2)Ti(2)O(5)S(2), the tetragonal symmetry of the host is retained: Li(0.30(5))Y(2)Ti(2)O(5)S(2), I4/mmm, a = 3.80002(2) A, c = 22.6396(2) A, Z = 2. The lithium ion occupies a site coordinated by four oxide ions in an approximately square planar geometry in the perovskite-like oxide slabs of the structure. At higher levels of lithium intercalation, the symmetry of the cell is lowered to orthorhombic: Li(0.99(5))Y(2)Ti(2)O(5)S(2), Immm, a = 3.82697(3) A, b = 3.91378(3) A, c = 22.2718(2) A, Z = 2, with ordering of Li(+) ions over two inequivalent sites. At still higher levels of lithium intercalation, tetragonal symmetry is regained: Li(1.52(5))Y(2)Ti(2)O(5)S(2), I4/mmm, a = 3.91443(4) A, c = 22.0669(3) A, Z = 2. A phase gap exists close to the transition from the tetragonal to orthorhombic structures (0.6 < x < 0.8). The changes in symmetry of the system with electron count may be considered analogous to a cooperative electronically driven Jahn-Teller type distortion. Magnetic susceptibility and resistivity measurements are consistent with metallic properties for x > 1, and the two-phase region is identified as coincident with an insulator to metal transition.
RECOMMENDER SYSTEM FOR AUDIO RECORDINGS (2010)

Nowadays the largest E-commerce or E-service websites offer millions of products for sale. A Recommender system is defined as software used by such websites for recommending commercial or noncommercial product items to users according to the users’ tastes. In this project, we develop a recommender system for a private multimedia web service company. In particular, we devise three recommendation engines using different data filtering methods – named weighted-average, K-nearest neighbors, and item-based – which are based on collaborative filtering techniques, which work by recording user preferences on items and by anticipating the future likes and dislikes of users by comparing the records, for prediction of user preference. To acquire proper input data for the three engines, we retrieve data from database using three data collection techniques: active filtering, passive filtering, and item-based filtering. For experimental purpose we compare prediction accuracy of those three recommendation engines with the results from each engine and additionally we evaluate the performance of weighted-average method using an empirical analysis approach – a methodology which was devised for verification of predictive accuracy.
Disrupting Hedgehog May Reverse Advanced Cancer, If Only Temporarily (2009)

A drug has dramatically shrunk cancerous tumors by disrupting a key genetic pathway, although one deadly brain cancer quickly developed resistance. A study published online this week in Science describes the mechanism by which this resistance developed.
Effect of the Application of Human Amniotic Membrane on Rabbit Corneal Wound Healing After Excimer Laser Photorefractive Keratectomy (1998)

The application of amniotic membrane after PRK reduces keratocyte proliferation and corneal haze during corneal wound healing, possibly by reducing the infiltration of inflammatory cells and loss of keratocytes in the ablation area during the early postoperative period.
Polydnavirus DNA is integrated in the DNA of its parasitoid wasp host. (1991)

The polydnavirus Campoletis sonorensis virus (CsV) is present in the oviducts of all adult C. sonorensis female wasps and appears to be required for these wasps to parasitize hosts successfully. Physical mapping, Southern blot analysis, and nucleotide sequence analysis demonstrate that the viral DNA B-specific sequences in cloned wasp DNA are colinear with viral genomic segment DNA B from nucleocapsids and are covalently linked to nonviral wasp sequences. Integrated DNA B terminates in 59-nucleotide imperfect direct repeats, but a single repeat exists in the extrachromosomal superhelical viral DNA B. Sequences near each junction form imperfect inverted repeats with sequences near the ends of an internal viral 540-base-pair repeat element gene. CsV appears to be the first documented integrated, nonretroviral DNA virus of insects and probably is vertically transmitted as a provirus.
A Study on the Selection of Housing Type and Characteristics of Dwelling for Foreign Students in Korea (2006)

The purpose of this study is to find out the selection of housing type and the characteristics of dwelling of foreign students' residence in order to provide some information for better housing plans for foreign students in Korea. To analyze characteristics of dwelling, a questionnaire survey was conducted with 171 students who study in the university located in seoul, Korea. The results are summarized as follows: Overseas students in Korea can get from their house to school within 30 minutes and they spend more than 9 hours a day at home on average. Housing is one of the most important factors for oversea students. For the dormitory group, they chose their houses based on fee, distance from the school, stability, etc. The lodging group, chose their houses based on fee, distance from school, and Korean culture experience. The Go-Si-Won group chose their houses based on fee, distance from the school, privacy and so on.