gebhart/patrepeval huggingface dataset:
High-Performance Aminated Poly(phenylene sulfide)/ZnO Nanocomposites for Medical Applications (2014)

An aminated poly(phenylene sulfide) derivative (PPS-NH2) has been melt-blended with different contents of ZnO nanoparticles, and the morphology, thermal, mechanical, tribological, antibacterial, and dielectric properties of the resulting nanocomposites have been investigated. The nanoparticles were dispersed within the matrix without the need for surfactants or coupling agents. A gradual rise in the crystallization temperature and the degree of crystallinity was found with increasing ZnO loading, confirming that the nanoparticles act as nucleating agents for PPS-NH2 crystallization. The nanoparticles reduced the water absorption and strongly increased the thermal stability of the matrix, leading to an extraordinary increase in the initial degradation temperature of 80 °C at 8.0 wt % nanoparticle content. The results showed that the stiffness, strength, toughness, glass transition, and heat distortion temperature were remarkably enhanced, whereas the coefficient of thermal expansion decreased upon addition of ZnO, ascribed to strong hydrogen bonding interactions between the amino groups of the matrix and the hydroxyl moieties of the nanoparticles. Moreover, the nanocomposites retained the tensile properties after being exposed to several cycles of steam sterilization. More importantly, an unprecedented drop in wear rate of nearly 100-fold was attained in the nanocomposite with the highest loading, demonstrating the suitability of these nanoparticles for providing wear resistance to the matrix. All the nanocomposites displayed low dielectric constant and dielectric loss, hence can be employed as insulating materials in electrosurgical applications. They also exhibited active inhibition against both Gram-positive and Gram-negative bacteria, which was gradually enhanced with increasing ZnO content. These nanocomposites are suitable as lightweight high-performance materials in the field of medicine and dentistry.
EVALUATION OF ASCORBYL MONOESTERS FOR THE INHIBITION OF NITROSOPYRROLIDINE FORMATION IN A MODEL SYSTEM (1976)

ABSTRACT The effect of a number of ascorbic acid derivatives on the nitrosation of pyrrolidine was determined in a model system developed to simulate the lipid‐aqueous‐protein composition of bacon. Sodium ascorbate reduced nitrosopyrrolidine formation 43% in the aqueous phase, but had little effect in the lipid layer. The combination of several ascorbyl esters with sodium ascorbate increased the inhibitory effect to a high of 70% in the aqueous phase. In the lipid phase up to 49% reduction in nitrosation was observed.
Gain stabilisation of all-optical gain-clamped amplifierby usingFaraday rotator mirrors (1998)

The authors propose a novel configuration of all-optical gain-clamped amplifiers for suppressing the gain drift caused by polarisation fading of the feedback channel. It is shown experimentally that the gain drift of the clamped gain can be stabilised to within ±0.03 dB.
A model and regularization scheme for ultrasonic beamforming clutter reduction (2015)

Acoustic clutter produced by off-axis and multipath scattering is known to cause image degradation, and in some cases these sources may be the prime determinants of in vivo image quality. We have previously shown some success addressing these sources of image degradation by modeling the aperture domain signal from different sources of clutter, and then decomposing aperture domain data using the modeled sources. Our previous model had some shortcomings including model mismatch and failure to recover B-Mode speckle statistics. These shortcomings are addressed here by developing a better model and by using a general regularization approach appropriate for the model and data. We present results with L1 (lasso), L2 (ridge), and L1/L2 combined (elastic-net) regularization methods. We call our new method aperture domain model image reconstruction (ADMIRE). Our results demonstrate that ADMIRE with L1 regularization, or weighted toward L1 in the case of elastic-net regularization, have improved image quality. L1 by itself works well, but additional improvements are seen with elastic-net regularization over the pure L1 constraint. On in vivo example cases, L1 regularization showed mean contrast improvements of 4.6 and 6.8 dB on fundamental and harmonic images, respectively. Elastic net regularization (α = 0.9) showed mean contrast improvements of 17.8 dB on fundamental images and 11.8 dB on harmonic images. We also demonstrate that in uncluttered Field II simulations the decluttering algorithm produces the same contrast, contrast-tonoise ratio, and speckle SNR as normal B-mode imaging, demonstrating that ADMIRE preserves typical image features.
Mars Surface Ionizing Radiation Environment: Need for Validation (1999)

Protection against the hazards from exposure to ionizing radiation ramains an unresolved issue in the Human Exploration and Development of Space (HEDS) enterprise. major uncertainty is the lack of data on biological response to galactic cosmic ray (GCR) exposures but even a full understanding of the physical interaction of GCR with shielding and body tissues is not yet available and has a potentially large impact on mission costs. The general opinion is that the initial flights should be short-stay missions performed as fast as possible (so-called ''Sprint'' missions) to minimize crew exposure to the zero-g and space radiation environment, to ease requirements on system reliability, and to enhance the probability of mission success. short-stay missions tend to have long transit times and may not be the best option due to the relatively long exposure to zero-g and ionizing radiation. On the otherhand the short-transit missions tend to have long stays on the surface requiring an adequate knowledge of the surface radiation environment to estimate risks and to design shield configurations. Our knowledge of the surface environment is theoretically based on suffers from an incomplete understanding of the physical interactions of GCR with the Martian atmosphere, Martian surface, and intervening shield materials. An important component of Mars surface robotic exploration is the opportunity to test our understanding of the Mars surface environment.
Phosphorylation of the ATP-binding loop directs oncogenicity of drug-resistant BCR-ABL mutants (2006)

The success of targeting kinases in cancer with small molecule inhibitors has been tempered by the emergence of drug-resistant kinase domain mutations. In patients with chronic myeloid leukemia treated with ABL inhibitors, BCR-ABL kinase domain mutations are the principal mechanism of relapse. Certain mutations are occasionally detected before treatment, suggesting increased fitness relative to wild-type p210 BCR-ABL. We evaluated the oncogenicity of eight kinase inhibitor-resistant BCR-ABL mutants and found a spectrum of potencies greater or less than p210. Although most fitness alterations correlate with changes in kinase activity, this is not the case with the T315I BCR-ABL mutation that confers clinical resistance to all currently approved ABL kinase inhibitors. Through global phosphoproteome analysis, we identified a unique phosphosubstrate signature associated with each drug-resistant allele, including a shift in phosphorylation of two tyrosines (Tyr253 and Tyr257) in the ATP binding loop (P-loop) of BCR-ABL when Thr315 is Ile or Ala. Mutational analysis of these tyrosines in the context of Thr315 mutations demonstrates that the identity of the gatekeeper residue impacts oncogenicity by altered P-loop phosphorylation. Therefore, mutations that confer clinical resistance to kinase inhibitors can substantially alter kinase function and confer novel biological properties that may impact disease progression.
Health Policy: An Introduction to the Health Care System - A Required First-Year Course (2002)

No abstract available.
Nitric Oxide and Symptom Reduction in Schizophrenia (2013)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Psychiatry HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Psychiatry journal
Logged virtual memory (1995)

article Logged virtual memory Share on Authors: D. R. Cheriton Computer Science Department, Stanford University, Stanford, CA Computer Science Department, Stanford University, Stanford, CAView Profile , K. J. Duda Computer Science Department, Stanford University, Stanford, CA Computer Science Department, Stanford University, Stanford, CAView Profile Authors Info & Claims ACM SIGOPS Operating Systems ReviewVolume 29Issue 5Dec. 3, 1995 pp 26–38https://doi.org/10.1145/224057.224060Online:03 December 1995Publication History 7citation727DownloadsMetricsTotal Citations7Total Downloads727Last 12 Months2Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Twin-jet screech suppression (1990)

A facility test was performed on twin-jet configurations to determine the effectiveness of several concepts in suppressing the supersonic screech tones. Supersonic jet Mach numbers up to 1.75 were tested. The screech suppression concepts were tabs, lateral spacing, axial spacing, and secondary air jets. Acoustic and optical data were obtained. It was found that the twin-jet configuration can result in screech tone amplitudes as much as 20 dB higher than a single jet. Screech tone amplitudes up to 162 dB were measured. Small tabs located at the exit plane were shown to be very effective suppressors if they were large enough or if multiple tabs were installed. Lateral spacing can result in significant tone suppression, however, at certain spacings little suppression was achieved. Axial spacing resulted in essentially no suppression. The secondary air jet was shown to be a very effective suppressor of screech tones from a single jet but was not tested on the twin jet configuration.
Execution Patterns in Automatic Malware and Human-Centric Attacks (2008)

With the massive surges of new malware, the intuitive detection techniques currently used in most security tools deem ineffective. Consequently, we urgently need better solutions that are established on solid theoretical basis. It becomes, thus, necessary to search for more efficient techniques and algorithms as well as taxonomies and models for attacks and malware. We present, in this paper, the analysis we made on both automatic malware and human-centric attacks, which allowed us to construct a model for attack process. The main objective of this work is to construct a model that can aide in the generation of real attack scenarios and use it in the evaluation of Intrusion Detection Systems. However, the model described here could have many other potential uses. For example, it can be used for writing "execution- based" signatures, event correlation, penetration testing, security simulations as well as security educations.
Decoupled Plasma Source Technology: Process Region Choices For Silicide Etching (1997)

We have developed a decoupled plasma source (DPS) etcher for polysilicon and polycide etching. A series of experiments has been carried out to study polycide gate etching in the DPS etcher. By combining conventional techniques of process evaluation with in situ monitoring of ions and radical chemistry and with real-time ion flux density distribution measurements, we quantitatively determined trends in polycide processing and etching with simple Cl 2 and He/O 2 chemistry. Performance parameters, such as etch rate, etch rate microloading, etch rate uniformity, profile, profile microloading and profile uniformity on WSi x , oxide, polysilicon and photoresist, were measured at 24 points on the surface matrix. These results were correlated with the physical and chemical parameters of the decoupled plasma, such as ion flux distribution, DC-bias potential across the wafer, plasma ion composition and concentration of neutrals. A vertical profile can be obtained with highly selective polycide etch in a single step main etch with Cl 2 and He/O 2 using a decoupled plasma silicon etch reactor.
Twitter as a Sentinel in Emergency Situations: Lessons from the Boston Marathon Explosions (2013)

Immediately following the Boston Marathon attacks, individuals near the scene posted a deluge of data to social media sites. Previous work has shown that these data can be leveraged to provide rapid insight during natural disasters, disease outbreaks and ongoing conflicts that can assist in the public health and medical response. Here, we examine and discuss the social media messages posted immediately after and around the Boston Marathon bombings, and find that specific keywords appear frequently prior to official public safety and news media reports. Individuals immediately adjacent to the explosions posted messages within minutes via Twitter which identify the location and specifics of events, demonstrating a role for social media in the early recognition and characterization of emergency events. *Christopher Cassa and Rumi Chunara contributed equally to this work.
A new motion-adaptive video processing system for TV receivers and VCRs (1992)

A cost-effective motion-adaptive video processing system was developed for luma/chroma separation and frame recursive noise reduction, using only a 2-Mbit frame memory. The problem of aliasing due to subsampling and the problem of waveform deterioration due to band restriction were solved, and a method of chroma motion detection using interframe difference signals was developed. Therefore, the required frame memory capacity can be reduced without a performance compromise. The video processing part of this system was produced as a single-chip digital LSI and was installed in a home-use S-VHS format VCR. The result was improved picture quality for VCR recording and playback.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Integrated circuit mask generation using a raster scanned laser trimming system (1982)

Due to the character of the original source materials and the nature of batch digitization, quality control issues may be present in this document. Please report any quality issues you encounter to digital@library.tamu.edu, referencing the URI of the item.
Controlled release of curcumin from curcumin-loaded nanomicelles to prevent peritendinous adhesion during Achilles tendon healing in rats (2016)

We introduced curcumin-loaded nanomicelles into a tendon-healing model to evaluate their effects on tendon healing and adhesion. Three groups consisting of 36 rats underwent rupture and repair of the Achilles tendon. The treatment group received an injection of curcumin-loaded nanomicelles (gold nanorods [GNRs]-1/curcumin in polymeric nanomicelles [curc@PMs] at a dosage of 0.44 mg curcumin/kg in 0.1 mL saline) into the surgical site and exposed to laser postoperatively at weeks 1, 2, and 3, for three times 10 seconds each, on the surgical site in the rats that underwent tendon rupture and repair, while the other two groups received 0.44 mg curcumin/kg in 0.1 mL saline and 0.1 mL of saline, respectively. The specimens were harvested at 4 weeks and subjected to biomechanical and histological evaluation. The scoring results of tendon adhesion indicated that GNRs-1/curc@PMs group was in the lowest grade of peritendinous adhesions compared to the other groups. Histological assessment further confirmed the preventive effect of GNRs-1/curc@PMs on tendon adhesion. These findings indicated greater tendon strength with less adhesion in the group treated with GNRs-1/curc@PMs combined with laser exposure, and that nanoparticle-based therapy may be applied to prevent adhesion in clinical patients.
Robust Neural Machine Translation with Doubly Adversarial Inputs (2019)

Neural machine translation (NMT) often suffers from the vulnerability to noisy perturbations in the input. We propose an approach to improving the robustness of NMT models, which consists of two parts: (1) attack the translation model with adversarial source examples; (2) defend the translation model with adversarial target inputs to improve its robustness against the adversarial source inputs.For the generation of adversarial inputs, we propose a gradient-based method to craft adversarial examples informed by the translation loss over the clean inputs.Experimental results on Chinese-English and English-German translation tasks demonstrate that our approach achieves significant improvements ($2.8$ and $1.6$ BLEU points) over Transformer on standard clean benchmarks as well as exhibiting higher robustness on noisy data.
Interleukin 18 polymorphisms and its serum level in patients with multiple sclerosis (2019)

In this study, we showed the significant higher IL-18 serum level and significant different frequencies of two polymorphisms of IL-18 in MS patients. These results show the important roles of IL-18 in MS pathogenesis. However, more studies are needed to verify our results in larger sample size.
SHOC2 and CRAF Mediate ERK1/2 Reactivation in Mutant NRAS-mediated Resistance to RAF Inhibitor (2012)

ERK1/2 signaling is frequently dysregulated in tumors through BRAF mutation. Targeting mutant BRAF with vemurafenib frequently elicits therapeutic responses; however, durable effects are often limited by ERK1/2 pathway reactivation via poorly defined mechanisms. We generated mutant BRAF(V600E) melanoma cells that exhibit resistance to PLX4720, the tool compound for vemurafenib, that co-expressed mutant (Q61K) NRAS. In these BRAF(V600E)/NRAS(Q61K) co-expressing cells, re-activation of the ERK1/2 pathway during PLX4720 treatment was dependent on NRAS. Expression of mutant NRAS in parental BRAF(V600) cells was sufficient to by-pass PLX4720 effects on ERK1/2 signaling, entry into S phase and susceptibility to apoptosis in a manner dependent on the RAF binding site in NRAS. ERK1/2 activation in BRAF(V600E)/NRAS(Q61K) cells required CRAF only in the presence of PLX4720, indicating a switch in RAF isoform requirement. Both ERK1/2 activation and resistance to apoptosis of BRAF(V600E)/NRAS(Q61K) cells in the presence of PLX4720 was modulated by SHOC-2/Sur-8 expression, a RAS-RAF scaffold protein. These data show that NRAS mutations confer resistance to RAF inhibitors in mutant BRAF cells and alter RAF isoform and scaffold molecule requirements to re-activate the ERK1/2 pathway.
Stanene: Atomically Thick Free-standing Layer of 2D Hexagonal Tin (2016)

Stanene is one of most important of 2D materials due to its potential to demonstrate room temperature topological effects due to opening of spin-orbit gap. In this pursuit we report synthesis and investigation of optical properties of stanene up to few layers, a two-dimensional hexagonal structural analogue of graphene. Atomic scale morphological and elemental characterization using HRTEM equipped with SAED and EDAX detectors confirm the presence of hexagonal lattice of Sn atoms. The position of Raman peak along with the inter-planar 'd' spacing obtained from SAED for prepared samples are in good agreement with that obtained from first principles calculations and confirm that the sheets are not (111) α-Sn sheets. Further, the optical signature calculated using density functional theory at ~191 nm and ~233 nm for low buckled stanene are in qualitative agreement with the measured UV-Vis absorption spectrum. AFM measurements suggest interlayer spacing of ~0.33 nm in good agreement with that reported for epitaxial stanene sheets. No traces of oxygen were observed in the EDAX spectrum suggesting the absence of any oxidized phases. This is also confirmed by Raman measurements by comparing with oxidized stanene sheets.
Disperse fine equiaxed alpha alumina nanoparticles with narrow size distribution synthesised by selective corrosion and coagulation separation (2015)

Disperse fine equiaxed α-Al2O3 nanoparticles with narrow size distribution are important materials in nanotechnology and nanomaterials, but syntheses of disperse fine equiaxed α-Al2O3 nanoparticles usually result in fine γ-Al2O3 nanoparticles or large α-Al2O3 nanoparticles larger than 15 nm. α-Al2O3 has a higher surface energy than γ-Al2O3 and becomes thermodynamically not stable with respect to γ-Al2O3 at specific surface areas larger than 100 m(2)/g (at sizes smaller than 15 nm for spherical particles) at room temperature. So disperse fine equiaxed α-Al2O3 nanoparticles smaller than 15 nm with narrow size distribution are extremely difficult to synthesise. Here we show the successful synthesis of disperse fine equiaxed α-Al2O3 nanoparticles with average sizes below 10 nm and narrow size distribution by selective corrosion and refined fractionated coagulation separation. An almost fully dense nanocrystalline α-Al2O3 ceramic with a relative density of 99.5% and an average grain size of 60 nm can be sintered from disperse fine equiaxed α-Al2O3 nanoparticles with narrow size distribution.
Nucleotide Sequence of the 3'-terminal Half of Beet Yellows Closterovirus RNA genome: Unique Arrangement of Eight Virus Genes (1991)

The sequence of 6746 nucleotides representing the 3'-proximal half of the beet yellows closterovirus (BYV) genome was determined. In the direction 5' to 3', the sequence was composed of eight open reading frames (ORFs) potentially encoding proteins of 6.4K (ORF2), 65K (ORF3), 64K (ORF4), 24K (ORF5), 22K (ORF6), 20K (ORF7) and 21K (ORF8). An incomplete ORF, ORF1, encoded the C-terminal part of a putative RNA-dependent RNA polymerase, most closely related to polymerases of tricornaviruses; the putative product of ORF3, 65K, was found to be a homologue of the hsp70 family of cell heat-shock proteins. ORF2 potentially encoded a small hydrophobic 6.4K protein, apparently homologous to small hydrophobic proteins of potex- and carlaviruses. ORF6 encoded the viral coat protein, as indicated by its deduced Mr and amino acid composition. The products of ORFs 4, 5, 7 and 8 showed no significant similarities with protein sequences in the database and there are therefore no justifiable speculations concerning their possible functions. BYV RNA contains a 3'-terminal non-coding region of 181 nucleotides, with two stem-loop structures potentially folded within the 86 nucleotide sequence at the extreme 3' end. Analysis of the primary and secondary structure of this region together with the absence of aminoacylation and adenylylation in vitro showed that the BYV genome is devoid of a tRNA-like structure at its 3' end.
The epidemiology of psoriatic arthritis in Olmsted County, Minnesota, USA, 1982-1991. (2000)

Unlike results from previous referral based studies, our findings indicate that PsA is a mild, uncommon inflammatory arthritis, not associated with a significant increase in mortality.