gebhart/patrepeval huggingface dataset:
Gender and Vascular Complications in the JAK2 V617F-Positive Myeloproliferative Neoplasms (2011)

We previously found that gender influenced the JAK2 V617F allele burden, but it is unknown whether this gender difference in molecular epidemiology influences complications in the myeloproliferative neoplasms (MPNs). Historically, vascular complications represented the most common cause of mortality in polycythemia vera and essential thrombocytosis and contributed to morbidity in primary myelofibrosis. To determine the influence of gender on vascular complications, we retrospectively analyzed associations between gender and vascular complications. Despite their younger age, less prevalent dyslipidemia or smoking history, lower white blood counts, and lower JAK2 V617F allele burden, women had higher rates of abdominal venous thrombosis and comparable rates of all vascular complications. Vascular risk is currently not easily stratified by MPN-disease burden or traditional risk factors. Our analysis contributes to growing literature emphasizing gender differences in the MPN and further supports the important impact of individual and host variation on MPN clinical manifestations, and especially vascular risk.
Flexible Imputation of Missing Data (2012)

Missing data form a problem in every scientific discipline, yet the techniques required to handle them are complicated and often lacking. One of the great ideas in statistical science-multiple imputation-fills gaps in the data with plausible values, the uncertainty of which is coded in the data itself. It also solves other problems, many of which a
Privacy algorithm for cylindrical holographic weapons surveillance system (2003)

A novel personnel surveillance system has been developed to detect and identify threatening objects, which are undetectable by metal detectors, concealed on the human body. This new system can detect threats, which are fabricated with plastic, liquid, metal, or ceramic. It uses millimeter-wave array technology and a cylindrical holographic imaging algorithm to provide full-body, 360-degree coverage of a person in near real-time. This system is ideally suited for mass transportation centers such as airport checkpoints that require high throughput rates and full coverage. Research and development efforts are underway to produce a privacy algorithm that removes the human features from the images while identifying the potential threats. This algorithm locates and segments the threats and places them on a wire-frame humanoid representation. The research areas for this algorithm development include artificial neural networks, image processing, edge detection, and dielectric measurements. This system is operational and results from this test and the privacy algorithm will be discussed in this paper.
Bonding wire loop antenna built into standard BGA package for 60 GHz short-range wireless communication (2011)

The unlicensed 60 GHz frequency band is suitable for high-speed wireless systems with transmission rates of 1 Gbps or more. In this paper, we propose a bonding wire antenna built into a BGA package for 60 GHz short-range wireless communication. This antenna utilizes two bonding wires and a metal plate on an interposer in a BGA package and has a loop shape. The proposed antenna is built into a standard BGA package without special modification, so that it can be fabricated at low cost by conventional BGA package fabrication process. The first and unique evaluation of the antenna fully sealed by encapsulation resin was done by measurement. We describe the operation mechanism of the proposed antenna, the design procedure and the measurement results.
Randomized Trial of Reduced-Nicotine Standards for Cigarettes (2015)

In this 6-week study, reduced-nicotine cigarettes versus standard-nicotine cigarettes reduced nicotine exposure and dependence and the number of cigarettes smoked. (Funded by the National Institute on Drug Abuse and the Food and Drug Administration Center for Tobacco Products; ClinicalTrials.gov number, NCT01681875.).
Ursolic Acid Triggers Apoptosis and Bcl-2 Downregulation in MCF-7 Breast Cancer Cells (2009)

In this report we determine the ability of ursolic acid (UA) to induce apoptosis and to modulate glucocorticoid receptor (GR) and Activator Protein-1 (AP-1) in MCF-7 cells. The UA-induced apoptosis (53 microM), the PARP cleavage, and the decrease in Bcl-2 protein (53 microM) support the notion that UA induces apoptosis through the intrinsic mitochondrial pathway. UA binds GR (relative binding affinity: 2.57) and translocates GR into nucleus, suggesting its potential as a GR modulator. UA had no effect on GRE- or TRE-driven gene expression. In summary, UA is a GR modulator and may be considered as a potential anticancer agent in breast cancer.
Definition of Ross River Virus Vectors at Maroochy Shire, Australia (2000)

Evidence of Ross River (RR) virus infection in field-collected mosquitoes and data from laboratory vector competence experiments incriminated a range of mosquito species as important vectors of RR virus in Maroochy Shire, Queensland, Australia. Nine RR and 2 Barmah Forest virus isolates were recovered from 27,529 mosquitoes collected in light traps from Maroochy Shire during 1996. Nine of the 10 most abundant mosquito species collected in light traps were fed on blood containing the B94/20 strain RR isolated from Queensland in 1994. All species except for Culex sitiens Wiedemann were susceptible to experimental infection. Evidence of RR virus transmission to mice was found with Aedes vigilax (Skuse), Aedes funereus (Theobald), Aedes procax (Skuse), Culex annulirostris Skuse, Mansonia uniformis (Theobald) and Culex australicus Dobrotworsky & Drummond. Aedes notoscriptus (Skuse) and Aedes multiplex (Theobald) were susceptible to RR virus infection, although there was no evidence of virus transmission. Based on adult abundance and vector competence results, freshwater species such as Cx. annulirostris, Ae. procax, and Ae. funereus, and saltmarsh Ae. vigilax, appear to be important vectors of RR virus in Maroochy Shire and control programs should be revised to include these species.
Topoisomerase I levels in the NCI-60 cancer cell line panel determined by validated ELISA and microarray analysis and correlation with indenoisoquinoline sensitivity (2009)

Topoisomerase I (Top1) is a proven target for cancer therapeutics, and the level of Top1 in tumors has been used as a biomarker for chemotherapeutic efficacy. In this study, we report the development and validation of a two-site enzyme chemiluminescent immunoassay for Top1, which we used to measure Top1 levels in the NCI-60 cancer cell line panel. Top1 levels ranged from 0.9 to 9.8 ng/mL/microg protein extract in these cell lines. Levels varied both within and between cancer types but were generally highest in colon cancer and leukemia cell lines and lowest in central nervous system and renal cancer cell lines. Top1 mRNA levels in the NCI-60 cell lines were also measured by microarray; mRNA values generally showed a good correlation with protein levels (Pearson correlation = 0.8). When these expression levels were compared with the activity of the indenoisoquinoline class of Top1 inhibitors across the NCI-60 cell panel, low levels of Top1 were associated with increased resistance to these drugs. The results of our studies indicate that our Top1 assay can be used to quantify Top1 levels in untreated cells as well as cells treated with Top1 inhibitors and that the assay has the potential to be adapted for use in predicting clinical response to Top1-active antineoplastic agents.
Varietal Differences in the Total and Enantiomeric Composition of Theanine in Tea (1997)

Theanine is the main amino acid component in tea. It usually constitutes between 1 and 2% of the dry weight of the tea leaves. It is as prevalent in tea as all other free amino acids combined. Both enantiomers of theanine were found to have a similar sweet taste, with little or no aftertaste. It was found that black and half-green teas (except for Formosa Oolong) contained as much, or more, theanine as green teas. No correlation was found between the absolute concentration of theanine in tea and its enantiomeric composition. An inverse correlation was found between certain grades of tea (e.g., pekoe, Flowery Orange Pekoe, etc.) and the percent of d-theanine present. This could provide the basis for a reproducible, scientific method to grade and/or evaluate teas. Theanine slowly racemizes in aqueous solution. It also undergoes hydrolysis, particularly at basic pH values. By monitoring these processes, information may be gleaned on the production, storage, handling, and shipping of tea and tea products. Keywords: Racemization; beverage; d-amino acid; tea grades; cyclodextrin column; column switching
A proposal for multi-slot MAC layer operation for packet data channel in GSM (2002)

Within the ETSI SMG, a General Packet Radio Service (GPRS) is being specified as part of GSM Phase 2+. The GPRS will be based on a new type of logical radio channel optimized for packet data. The requirement for higher data rate, flexibility and efficient utilization of the scarce bandwidth across the air interface triggered the development of a multi-slot packet data channel concept, which is presented. Such a concept can be implemented on any TDMA system and even extended to a multi-carrier solution. The article describes the principles for dynamic bandwidth allocation based on multi-slot operation at the MAC layer in a master-slave channel concept. Further, an evaluation, through simulations, is done in order to compare the performance of multi-slot and earlier assumed single-slot MAC layer operation.
Fuel Cells: Principles, Types, Fuels, and Applications (2000)

During the last decade, fuel cells have received enormous attention from research institutions and companies as novel electrical energy conversion systems. In the near future, they will see application in automotive propulsion, distributed power generation, and in low power portable devices (battery replacement). This review gives an introduction into the fundamentals and applications of fuel cells: Firstly, the environmental and social factors promoting fuel cell development are discussed, with an emphasis on the advantages of fuel cells compared to the conventional techniques. Then, the main reactions, which are responsible for the conversion of chemical into electrical energy in fuel cells, are given and the thermodynamic and kinetic fundamentals are stated. The theoretical and real efficiencies of fuel cells are also compared to that of internal combustion engines. Next, the different types of fuel cells and their main components are explained and the related material issues are presented. A section is devoted to fuel generation and storage, which is of paramount importance for the practical aspects of fuel cell use. Finally, attention is given to the integration of the fuel cells into complete systems.
Leveraging Knowledge-based Inference for Material Classification (2015)

Material classification is one of the fundamental problems for multimedia content analysis, computer vision and graphics. Existing efforts mostly focus on extracting representative visual features and training a classifier to recognize unknown materials. Compared with human visual recognition, automatic recognition cannot leverage common sense knowledge regarding material categories and contextual information such as object and scene. In this paper, we propose to first extract such knowledge on material, object and scene from heterogeneous sources, i.e. a public data set of 100 million Flickr images [13] and Bing search results. To improve the material classification task, the knowledge information is further exploited in a probabilistic inference framework. Our method is evaluated on OpenSurfaces [10], the largest public material data set which contains both visual features of physical properties as well as image context information. The quantitative evaluation demonstrates the superior performance of our proposed method.
Rapid identification of nerve agents Sarin (GB) and Soman (GD) with the use of a field‐portable GC/SAW vapor detector and liquid desorption front‐end device (1999)

The nerve agents Sarin (GB) and Soman (GD) were detected at the picogram level with the use of a field-portable gas chromatograph with a surface-acoustic-wave detector (SAW). The instrument, although primarily a vapor detector, can be modified with a simple front-end thermostat attachment, which allows for small-volume liquid injections for the detection of analytes in the vapor-pressure range of 0.1–5.0 torr. A field analytical method was developed with the use of the analyte surrogates dimethyl methyl phosphonate (DMMP) and triethyl phosphate (TEP). These compounds were used as internal standards by which agents GB and GD can be detected, with the use of this liquid injection method coupled to the vapor detector. Actual tests on GB and GD were performed under the same conditions, but in a more closely monitored but less field-representative laboratory environment. GB was quantitated from a calibration plot that relates signal to mass via a conversion factor in less than 10 s. The turnaround time for the instrument between data sets was 2 min, depending on the exact parameters of the method. ©1999 John Wiley & Sons, Inc. Field Analyt Chem Technol 3:45–53, 1999
Determination of the chemical structure of the capsular polysaccharide of strain B33, a fast-growing soya bean-nodulating bacterium isolated from an arid region of China (2001)

We have determined the structure of a polysaccharide from strain B33, a fast-growing bacterium that forms nitrogen-fixing nodules with Asiatic and American soya bean cultivars. On the basis of monosaccharide analysis, methylation analysis, one-dimensional 1H- and 13C-NMR and two-dimensional NMR experiments, the structure was shown to consist of a polymer having the repeating unit → 6)-4-O-methyl-α-d-Glcp-(1 → 4)-3-O-methyl-β-d-GlcpA-(1 → (where GlcpA is glucopyranuronic acid and Glcp is glucopyranose). Strain B33 produces a K-antigen polysaccharide repeating unit that does not have the structural motif sugar-Kdx [where Kdx is 3-deoxy-d-manno-2-octulosonic acid (Kdo) or a Kdo-related acid] proposed for different Sinorhizobium fredii strains, all of them being effective with Asiatic soya bean cultivars but unable to form nitrogen-fixing nodules with American soya bean cultivars. Instead, it resembles the K-antigen of S. fredii strain HH303 (rhamnose, galacturonic acid)n, which is also effective with both groups of soya bean cultivars. Only the capsular polysaccharide from strains B33 and HH303have monosaccharide components that are also present in the surface polysaccharide of Bradyrhizobium elkanii strains, which consists of a 4-O-methyl-d-glucurono-l-rhamnan.
Fertilizer Salts Reduce Hydration of Polyacrylamide Gels and Affect Physical Properties of Gel-amended Container Media (1990)

Hydration of three commercial hydrophilic polyacrylamide gels in deionized water ranged from 340 to 420 g per gram of gel. Hydration was progressively inhibited by fertilizer salt concentrations from 0 to 20 meq·liter -1 . Hydration of the gels in the presence of divalent cations (Ca 2+ and Mg 2+ ) and monovalent cations (K+ and NH 4 + ) at 20 meq·liter -1 was reduced to ≈10% and 20% of maximum, respectively. The valence of the accompanying anion did not affect hydration. Gel hydration was unaffected by urea over the range of 2 to 20 m m . Sequential rinses of the hydrated gels with deionized water completely reversed the inhibition due to the monovalent, but not the divalent, cations. The electroconductivity (EC) of the external solution increased during gel hydration. In the presence of fertilizer salts, the physical properties of a 2 redwood sawdust : 1 sand (v/v) container mix were unaffected by hydrophilic gel additions of 1.2 and 2.4 kg·m -3 (1 × and 2 × the recommended rate, respectively).
The Crystal Structure of<i>Escherichia coli</i>Group 4 Capsule Protein GfcC Reveals a Domain Organization Resembling That of Wza (2011)

We report the 1.9 Å resolution crystal structure of enteropathogenic Escherichia coli GfcC, a periplasmic protein encoded by the gfc operon, which is essential for assembly of group 4 polysaccharide capsule (O-antigen capsule). Presumed gene orthologs of gfcC are present in capsule-encoding regions of at least 29 genera of Gram-negative bacteria. GfcC, a member of the DUF1017 family, is comprised of tandem β-grasp (ubiquitin-like) domains (D2 and D3) and a carboxyl-terminal amphipathic helix, a domain arrangement reminiscent of that of Wza that forms an exit pore for group 1 capsule export. Unlike the membrane-spanning C-terminal helix from Wza, the GfcC C-terminal helix packs against D3. Previously unobserved in a β-grasp domain structure is a 48-residue helical hairpin insert in D2 that binds to D3, constraining its position and sequestering the carboxyl-terminal amphipathic helix. A centrally located and invariant Arg115 not only is essential for proper localization but also forms one of two mostly conserved pockets. Finally, we draw analogies between a GfcC protein fused to an outer membrane β-barrel pore in some species and fusion proteins necessary for secreting biofilm-forming exopolysaccharides.
<scp>ISPAD</scp> Clinical Practice Consensus Guidelines 2022: Stages of type 1 diabetes in children and adolescents (2022)

The authors have declared no conflicts of interest. The peer review history for this article is available at https://publons.com/publon/10.1111/pedi.13410. Data sharing not applicable to this article as no datasets were generated or analysed during the current study.
Resource Usage Prediction Models for Optimal Multimedia Content Provision (2016)

This paper proposes a network architecture that utilizes novel resource prediction models for optimal selection of multimedia content provision methods. The proposed research approach is based on a prototype system, which exploits a resource prediction engine (RPE), utilizing time series and epidemic spread models, for optimal and balanced distribution of the streaming data among content delivery networks, cloud-based providers and home media gateways. The proposed epidemic diseases models adopt the characteristics of the multimedia content delivery over the network architecture. In this context, this paper aims to present the advantages of using such models, by presenting and analyzing an epidemic spread scheme for video-on-demand (VoD) delivery, to predict future epidemic spread behavior. In addition, this paper presents two algorithms, adopted in the prototype network architecture, for optimal selection of multimedia content delivery methods, as well as balanced delivery load, by exploiting the RPE. Both algorithms and models are evaluated to establish their efficiency, toward effectively predicting future network traffic demands. The simulation results verify the validity of the proposed approach, identifying fields for future research and experimentation.
A Wavelet-Based Encoding Algorithm for High Dynamic Range Images~!2010-02-25~!2010-04-23~!2010-06-10~! (2010)

High Dynamic Range (HDR) images use a wider range of intensity values than the common Limited Dynamic Range (LDR) images. Because of this, handling HDR images requires a great deal of information to be stored and transferred. To represent and display HDR images efficiently, a trade-off needs to be balanced between size and accuracy. We present a new wavelet-based algorithm for encoding HDR images, so that their data are feasible in the internet-based society for image communication. Experiments are conducted using the library provided by the Munsell Color Science Laboratory of Rochester Institute of Technology and HDR Images provided by Industrial Light and Magic (ILM, a motion picture visual effects company). Experimental results show that the encoded format is able to achieve a good balance between visual quality and image size for internet users.
Trichloroisocyanuric Acid:  A Safe and Efficient Oxidant (2002)

ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTTrichloroisocyanuric Acid: A Safe and Efficient OxidantUlf Tilstam and Hilmar WeinmannView Author Information Process Research, Schering AG-Berlin, D-13342 Berlin, Germany Cite this: Org. Proc. Res. Dev. 2002, 6, 4, 384–393Publication Date (Web):June 22, 2002Publication History Received12 November 2001Published online22 June 2002Published inissue 1 July 2002https://pubs.acs.org/doi/10.1021/op010103hhttps://doi.org/10.1021/op010103hreview-articleACS PublicationsCopyright © 2002 American Chemical SocietyRequest reuse permissionsArticle Views11426Altmetric-Citations181LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Alcohols,Ethers,Halogenation,Oxidation,Reagents Get e-Alerts
A framework for modeling appearance change in image sequences (2002)

Image "appearance" may change over time due to a variety of causes such as: 1) object or camera motion; 2) generic photometric events including variations in illumination (e.g. shadows) and specular reflections; and 3) "iconic changes" which are specific to the objects being viewed and include complex occlusion events and changes in the material properties of the objects. We propose a general framework for representing and recovering these "appearance changes" in an image sequence as a "mixture" of different causes. The approach generalizes previous work on optical flow to provide a richer description of image events and more reliable estimates of image motion.
Stencil Nano Lithography Based on a Nanoscale Polymer Shadow Mask: Towards Organic Nanoelectronics (2015)

A stencil lithography technique has been developed to fabricate organic-material-based electronic devices with sub-micron resolution. Suspended polymethylmethacrylate (PMMA) membranes were used as shadow masks for defining organic channels and top electrodes. Arrays of pentacene field effect transistors (FETs) with various channel lengths from 50 μm down to 500 nm were successfully produced from the same batch using this technique. Electrical transport measurements showed that the electrical contacts of all devices were stable and the normalized contact resistances were much lower than previously studied organic FETs. Scaling effects, originating from the bulk space charge current, were investigated by analyzing the channel-length-dependent mobility and hysteresis behaviors. This novel lithography method provides a reliable means for studying the fundamental transport properties of organic materials at the nanoscale as well as enabling potential applications requiring the fabrication of integrated organic nanoelectronic devices.