gebhart/patrepeval huggingface dataset:
A software classification scheme (1985)

Reusing code is one approach to software reusability. Code is the end product of the software lifecycle. It is delivered in a low level representation that is difficult to reuse unless an almost perfect match exists between available features and required specifications. There is a need to organize large inventories of software such that reusable code is easy to locate and exchange. The relative success in the reuse of code fragments reported by some software factories is due in part to their capacity to encapsulate domain specific functions and create specialized libraries of components classified by these locally standardized functions.A general software classification scheme that organizes reusability related attributes and common functions from different domains is proposed as a partial solution to the software reusability problem. For the problem of selecting from similar, potentially reusable. components, a partial solution based on evaluation of common characteristics is also proposed. A library system is presented that integrates the proposed classification scheme with an evaluation mechanism based on inherent component attributes, programming languages characteristics and reuser experience.The fundamental contribution of this dissertation is a formal treatment of a faceted scheme for software classification leading to better understanding of reusability at the code level. This approach has been prototyped in a library system for the semi-automatic classification of software components. Analysis were performed to evaluate the classification scheme. The results show the potential of the scheme in organizing collections of code fragments, in improving retrieval, and in simplifying the classification process. Tests of the evaluation mechanism showed positive correlation with evaluations conducted by potential reusers.
Flavonoids of Vitex negundo (1979)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFlavonoids of Vitex negundoPrema M. Subramanian and G. S. MisraCite this: J. Nat. Prod. 1979, 42, 5, 540–542Publication Date (Print):September 1, 1979Publication History Published online1 July 2004Published inissue 1 September 1979https://pubs.acs.org/doi/10.1021/np50005a019https://doi.org/10.1021/np50005a019research-articleACS PublicationsRequest reuse permissionsArticle Views232Altmetric-Citations17LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Real-space imaging of molecular structure and chemical bonding by single-molecule inelastic tunneling probe (2014)

The arrangement of atoms and bonds in a molecule influences its physical and chemical properties. The scanning tunneling microscope can provide electronic and vibrational signatures of single molecules. However, these signatures do not relate simply to the molecular structure and bonding. We constructed an inelastic tunneling probe based on the scanning tunneling microscope to sense the local potential energy landscape of an adsorbed molecule with a carbon monoxide (CO)-terminated tip. The skeletal structure and bonding of the molecule are revealed from imaging the spatial variations of a CO vibration as the CO-terminated tip probes the core of the interactions between adjacent atoms. An application of the inelastic tunneling probe reveals the sharing of hydrogen atoms among multiple centers in intramolecular and extramolecular bonding.
LensXPlain (2019)

In this demonstration, we will present LensXPlain, an interactive system to help users understand answers of aggregate queries by providing meaningful explanations. Given a SQL group-by query and a question from a user " why output o is high/low ", or " why output o 1 is higher/lower than o 2 ", LensXPlain helps users explore the results and find subsets of tuples captured by predicates that contributed the most toward such observations. The contributions are measured either by intervention (if the contributing tuples are removed, the values or the ratios in the user question change in the opposite direction), or by aggravation (if the query is restricted to the contributing tuples, the observations change more in the same direction). LensXPlain uses ensemble learning for recommending useful attributes in explanations, and employs a suite of optimizations to enable explanation generation and refinement at an interactive speed. In the demonstration, the audience can run aggregation queries over real world datasets, browse the answers using a graphical user interface, ask questions on unexpected/interesting query results with simple visualizations, and explore and refine explanations returned by LensXPlain.
Modeling Liver Fibrosis in Rodents (2005)

Animal models of hepatic fibrosis provide a means to study the cell and molecular mediators of fibrosis in a serial manner during both progression and recovery. Several approaches to induction of fibrosis have been described. Of these, CCl(4) intoxication in rats and mice is probably the most widely studied. In addition, the CCl(4) model is the best characterized with respect to histological, biochemical, cell, and molecular changes associated with the development of fibrosis. CCl(4) can be given intraperitoneally or by oral gavage; it induces zone III necrosis and hepatocyte apoptosis with associated hepatic stellate cell activation and tissue fibrosis. With repetitive dosing CCl(4) can be used to induce bridging hepatic fibrosis (4 wk of twice-weekly dosing), cirrhosis (8 wk of twice-weekly dosing) and advanced micronodular cirrhosis (12 wk of twice-weekly dosing). In addition, for each of these models spontaneous recovery from fibrosis can be studied after cessation of dosing. Mechanistic studies using gene knockout and transgenic animals can also be established using CCl(4). Together these models have provided unparalleled insights into the mechanisms underlying hepatic fibrosis.
20.7 A multi-band inductor-less SAW-less 2G/3G-TD-SCDMA cellular receiver in 40nm CMOS (2014)

The growing demand for high-speed wireless communication has driven the evolution of cellular phone networks. New-generation cellular standards use wider channel bandwidth and more sophisticated modulation to obtain higher data-rates. Due to various cellular standards, chip providers are required to offer highly integrated solutions that support 2G, 3G, and even 4G in one chip. This paper presents a receiver supporting 2G quad bands and 3G TD-SCDMA dual bands. Figure 20.7.1 shows the 2G/3G receiver, whose front-end current-mode outputs are combined at baseband CR filter and biquad PGA, which are shared between all bands. A dynamic gain-bandwidth-product-extension circuit technique is used to remove a transimpedance amplifier to save die area and current.
Mechanisms of skeletal muscle depletion in wasting syndromes: role of ATP-ubiquitin-dependent proteolysis (2003)

As the present overview points out, several questions still remain unanswered in the issue of muscle wasting. While many different signals that have the potential to enforce the acceleration of muscle protein breakdown have been identified, it is largely unknown how they are transduced and converge into the hypercatabolic response and how the proteolytic pathways involved are activated. The concept seems to emerge that there may be a coordinated action of different proteolytic pathways in setting up muscle protein turnover towards excess catabolism.
Thermal cycle properties of plasma sprayed YSZ/Al<sub>2</sub>O<sub>3</sub> thermal barrier coatings (2008)

In the present study, yttria partially stabilised zirconia (YSZ)/Al 2 O 3 coatings, which are used for jet engines, gas turbines and diesel engines were coated with thermal barrier coatings to provide high thermal resistance, reduce the metal surface temperatures and increase component durability. The effect of alumina addition from 0 to 80 wt-% on the properties of plasma sprayed YSZ coatings was investigated. The coating comprised of YSZ–Al 2 O 3 (0, 20, 50 and 80 wt- %Al 2 O 3 ); NiCrAlY bond coat; and AISI 304L stainless steels substrates. Scanning electron microscopy was used to analyse the microstructures of the coated samples. Thermal shock tests were performed over the specimens, at 1000 and 1200°C for 5 min and then forced air quenching for 2 min. The microhardness was investigated depending on the alumina contents. Vickers hardness on cross-section of coatings was observed to increase with the increase in alumina mixing ratio. It was noticed that with increase in Al 2 O 3 content the thermal shock life of the specimens decreased.
El control de la producción y del tráfico ilícito de armas livianas: la agenda global (1997)

servir a una necesidad comn o alcanzar un objetivo en comn. No existe tal asociacin emergente para comb3tir amenazas comunes
A Phase I Clinical Trial of AZD1775 in Combination with Neoadjuvant Weekly Docetaxel and Cisplatin before Definitive Therapy in Head and Neck Squamous Cell Carcinoma (2018)

Abstract Purpose: The WEE1 tyrosine kinase regulates G2–M transition and maintains genomic stability, particularly in p53-deficient tumors which require DNA repair after genotoxic therapy. Thus, a need arises to exploit the role of WEE1 inhibition in head and neck squamous cell carcinoma (HNSCC) mostly driven by tumor-suppressor loss. This completed phase I clinical trial represents the first published clinical experience using the WEE1 inhibitor, AZD1775, with cisplatin and docetaxel. Patients and Methods: We implemented an open-label phase I clinical trial using a 3+3 dose-escalation design for patients with stage III/IVB HNSCC with borderline-resectable or -unresectable disease, but who were candidates for definitive chemoradiation. Escalating AZD1775 was administered orally twice a day over 2.5 days on the first week, then in combination with fixed cisplatin (25 mg/m2) and docetaxel (35 mg/m2) for 3 additional weeks. The primary outcome measure was adverse events to establish MTD. Secondary measures included response rates, pharmacokinetics (PK), pharmacodynamics, and genomic data. Results: The MTD for AZD1775 was established at 150 mg orally twice per day for 2.5 days. RECISTv1.1 responses were seen in 5 of 10 patients; histologic adjustment revealed three additional responders. The only drug-limiting toxicity was grade 3 diarrhea. The PK C8hr target of 240 nmol/L was achieved on day 4 at all three doses tested. Pharmacodynamic analysis revealed a reduction in pY15-Cdk, and increases in γH2AX, CC3, and RPA32/RPA2 were noted in responders versus nonresponders. Conclusions: The triplet combination of AZD1775, cisplatin, and docetaxel is safe and tolerable. Preliminary results show promising antitumor efficacy in advanced HNSCC, meriting further investigation at the recommended phase II dose. Clin Cancer Res; 24(12); 2740–8. ©2018 AACR.
Dynamic properties of 1.3 µm semi-insulating-BHlight-emission-and-detection(LEAD)-diode module forsubscriber TCM transmission systems (1995)

The dynamic properties of a 1.3 µm light-emission-and-detection (LEAD)-diode module that has a high mesa semi-insulating buried heterostructure (SI-BH) to reduce the capacitance of the chip (0.6–0.8 pF) are described. A modulation bandwidth of 12 GHz in laser diode (LD) operation, and detection bandwidth of ~1.9 GHz in photodetector (PD) operation are achieved using a chip and a module, respectively. In bit error rate (BER) performance at 30 Mbit/s, a receiver sensitivity (BER = 10-8) of –37.4 dBm is confirmed, and a switching time of under 1 µs from LD to PD operation is estimated using a circuit simulator.
Autophagy and cell death (2012)

Autophagy exerts dual functions in cancer, acting as both a tumor suppressor, for example, by preventing the accumulation of damaged proteins and organelles, and as a tumor promoter that supports tumor growth. Many anticancer therapies engage autophagy as part of a cellular response. However, the question of whether or not autophagic activity in cells undergoing cell death is the cause of death or whether it is actually an attempt to support survival in response to cellular stress conditions has been discussed with great controversy.
Laboratory Measurement of Hydraulic Fracture Conductivities in the Barnett Shale (2013)

Abstract Horizontal wells intersecting multistage transverse fractures created by low viscosity fracturing fluid with low proppant loadings are the key to revitalizing production from the Mississippian Barnett shale of the Fort Worth Basin in Texas. However, direct laboratory measurements of both natural and induced fracture conductivities under realistic experimental design conditions are needed for reliable well performance analysis and fracture design optimization. In this work, a series of experiments were conducted to measure the conductivity of unpropped natural fractures, propped natural fractures, unpropped induced fractures and propped induced fractures using a modified API conductivity cell at room temperature. Fractures were induced along the natural bedding planes preserving fracture surface asperities. Natural fracture infill was kept for initial conductivity measurements and then removed for subsequent propped fracture conductivity tests. Proppants of various sizes were manually placed between rough fracture surfaces at realistic concentrations. The two sides of the rough fractures were either aligned or displaced with a 0.1 inch offset. After pressure testing on the system integrity, nitrogen was flown through the proppant pack or unpropped fracture to measure the conductivity. Results from the 88 experiments show that the conductivity of hydraulic fractures in shale can be accurately measured in a laboratory with appropriate experimental procedures and good control on experimental errors. It is proved that unpropped induced fractures can provide a conductive path after removal of free particles and debris due to the brittleness and lamination of shale. Moreover, poorly cemented natural fractures and unpropped displaced fractures can create conductivities up to 0.5 md-ft at formation closure stress, which is one order of magnitude higher than the conductivity provided by cemented natural fractures and unpropped aligned fractures. This study shows that propped fracture conductivity increases with larger proppant size and higher proppant concentration. Longer term fracture conductivity measurements also show that within 20 hours the fracture conductivity could be reduced by as much as 20%.
A Cyclophilin Function in Hsp90-Dependent Signal Transduction (1996)

Cpr6 and Cpr7, the Saccharomyces cerevisiae homologs of cyclophilin-40 (CyP-40), were shown to form complexes with Hsp90, a protein chaperone that functions in several signal transduction pathways. Deletion of CPR7 caused severe growth defects when combined with mutations that decrease the amount of Hsp90 or Sti1, another component of the Hsp90 chaperone machinery. The activities of two heterologous Hsp90-dependent signal transducers expressed in yeast, glucocorticoid receptor and pp60(v-src) kinase, were adversely affected by cpr7 null mutations. These results suggest that CyP-40 cyclophilins play a general role in Hsp90-dependent signal transduction pathways under normal growth conditions.
Cardiomyocyte Proliferation: A Platform for Mammalian Cardiac Repair (2005)

Permanent loss of heart muscle cells, cardiomyocytes, is a major mechanism resulting in ventricular dysfunction and heart failure. Potential solutions to this problem could be either to stimulate the heart to generate new cells by inducing existing cardiomyocytes to divide or to activate or deliver stem cells/ progenitor cells to multiply and subsequently differentiate into cardiomyocytes. Utilizing in vitro and in vivo approaches, p38 MAP kinase has recently been identified as a key negative regulator of cardiomyocyte proliferation. This work provides strong evidence that adult mammalian cardiomyocytes can divide. This review discusses the potential of the induction of mammalian cardiomyocyte proliferation as a therapeutic strategy for myocardial repair.
Sensorless Control of a Grid-Connected PV Converter (2006)

The base of our new developed grid-connected PV converter is a low cost general purpose frequency converter. In spite of the lack of voltage sensors a very reliable anti-island protection is reached. In the first section a control structures of the grid-connected converter with UVOC (Utility Voltage Oriented Control) is given while in the second section a method for the sensorless identification of the grid voltage is suggested. The third section describes an ultimate method for anti-island protection with a negligible none-detection zone. Finally the experimental results of the developed low cost general purpose frequency converter are presented.
The Transport Properties of Carbon Dioxide (1990)

The paper contains new, representative equations for the viscosity and thermal conductivity of carbon dioxide. The equations are based in part upon a body of experimental data that have been critically assessed for internal consistency and for agreement with theory whenever possible. In the case of the low-density thermal conductivity at high temperatures, all available data are shown to be inconsistent with theoretical expectation and have therefore been abandoned in favor of a theoretical prediction. Similarly, the liquid-phase thermal conductivity has been predicted owing to the small extent and poor quality of the experimental information. In the same phase the inconsistencies between the various literature reports of viscosity measurements cannot be resolved and new measurements are necessary. In the critical region the experimentally observed enhancements of both transport properties are well represented by theoretically based equations containing just one adjustable parameter. The complete correlations cover the temperature range 200 K≤T&lt;1500 K for viscosity and 200 K≤T≤1000 K for thermal conductivity, and pressures up to 100 MPa. The uncertainties associated with the correlation vary according to the thermodynamic state from ±0.3% for the viscosity of the dilute gas near room temperature to ±5% for the thermal conductivity in the liquid phase. Tables of the viscosity and thermal conductivity generated by the representative equations are provided to assist with the confirmation of computer implementations of the calculation procedure.
Effects of shaping of binaural room impulse responses on localization (2013)

This contribution describes effects on perceived direction, distance, and externalization of auditory events by changing or shaping two energy based parameters of recorded binaural room impulse responses using a binaural headphone synthesis. A controlled modification of the distance perception in non-individualized binaural headphone reproduction is presented and evaluated. The algorithms change systematically time and energy based distance-dependent properties of impulse responses. The new binaural room impulse responses (BRIRs) are shaped by an energy adaption based on the initial time delay gap. Listening tests show that measured BRIRs and the newly synthesized BRIRs cause similar distance perception. In a second experiment the direct-to-reverberant-ratio (DRR) is changed until the test person perceived congruence between the synthesized and the listening room. All of the presented tests also investigate perceptual effects of congruence and divergence between the synthesized room and the listening room.
A New Technique for the Digitization and Restoration of Deteriorated Photographic Negatives (2009)

This work describes the development and analysis of a new image-based photonegative restoration system. Deteriorated acetate-based safety negatives are complex objects due to the separation and channeling of their multiple layers that has often occurred over 70 years time. Using single-scatter diffuse transmission model, the intrinsic intensity information and shape distortion of film can be modeled. A combination of structured-light and high-dynamic range imaging is used to acquire the data which allows for automatic photometric and geometric correction of the negatives. This is done with a simple-to-deploy and cost-effective camera and LCD system that are already available to most libraries and museums. An initial analysis is provided to show the accuracy of this method and promising results of restoration of actual negatives from a special archive collection are then produced.
Aluminum-27 nuclear magnetic resonance study of the room-temperature melt aluminum trichloride butylpyridinium chloride (1981)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAluminum-27 nuclear magnetic resonance study of the room-temperature melt aluminum trichloride butylpyridinium chlorideJoel L. Gray and Gary E. MacielCite this: J. Am. Chem. Soc. 1981, 103, 24, 7147–7151Publication Date (Print):December 1, 1981Publication History Published online1 May 2002Published inissue 1 December 1981https://pubs.acs.org/doi/10.1021/ja00414a018https://doi.org/10.1021/ja00414a018research-articleACS PublicationsRequest reuse permissionsArticle Views507Altmetric-Citations73LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts