gebhart/patrepeval huggingface dataset:
A New Polycondensation Process for the Preparation of Polysiloxane Copolymers (2005)

ADVERTISEMENT RETURN TO ISSUEPREVCommunication to the...Communication to the EditorNEXTA New Polycondensation Process for the Preparation of Polysiloxane CopolymersSlawomir Rubinsztajn and James A. CellaView Author Information General Electric Company, Global Research Center, 1 Research Circle, Niskayuna, New York 12309 Cite this: Macromolecules 2005, 38, 4, 1061–1063Publication Date (Web):January 25, 2005Publication History Received30 September 2004Revised10 December 2004Published online25 January 2005Published inissue 1 February 2005https://pubs.acs.org/doi/10.1021/ma047984nhttps://doi.org/10.1021/ma047984nrapid-communicationACS PublicationsCopyright © 2005 American Chemical SocietyRequest reuse permissionsArticle Views2858Altmetric-Citations141LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Addition reactions,Condensation,Copolymers,Polymers,Siloxanes Get e-Alerts
A Study of Tibial Nerve in the Popliteal Fossa Along With Its Variations in Its Branching Pattern (2020)

Background: A detailed Knowledge of these variations in motor branching patterns will help the surgeons when certain procedures are done for calf reduction and also when selective neurectomy is required. It is also required by the anesthetists to give neurolytic blocks. Subjects and Methods: 40 formalin-fixed lower limbs of adult human cadavers were selected. The origin of the tibial nerve, variations in a branching pattern, number of muscular branches given was studied by dissection. The Level of origin of these nerves was taken to the apex of the head of the fibula (AHF). Results: In 70 % of specimens the origin of the Tibial Nerve was < 12 cm and in 30 % it was between 12-24 cm above the level of AHF. In 10% of cases, the sural nerve originated from the nerve to the medial head of gastrocnemius (MHG). In 82.5% of specimens, the MHG received one branch from the tibial nerve and in 17.5% it received two branches. The lateral head of Gastrocnemius (LHG) received one branch from the tibial nerve. In 10%, there was a common branch for the LHG and the soleus muscle. 90% of specimens had one branch and 10% had two branches that supplied the soleus muscle. A single branch supplied the plantaris muscle. The popliteus muscle also received a single branch. Conclusion : The results in the study provide information that is required by the anatomists, surgeons, radiologists and anesthetists.
Antibody MT3 is reactive with a novel exon B-associated 190-kDa sialic acid-dependent epitope of the leukocyte common antigen complex (1991)

MT3 is a new antibody reactive with a restricted isoform of the leukocyte common Ag (CD45) family. The Ag is mainly expressed on T lymphocytes and thymocytes. It is differentially expressed on B cell subpopulations, with no staining of the majority of small follicular mantle zone B cells but positive staining of the majority of marginal zone B cells of spleen. Like most CD45 antibodies, reactivity can be demonstrated in fresh frozen as well as in formalin-fixed, paraffin-embedded tissues. This reactivity clearly differs from all other published anti-CD45 antibodies. In immunoprecipitation and Western blot procedures, the antibody reacts with a major band with a molecular mass of 190 kDa and weak bands with molecular masses of 205 and 220 kDa. Compared to antibody PD7 that reacts with exon B-encoded sequences, the reactivity with the 205 and 220 bands is much weaker. This is reflected in MT3 reactivity with leukocyte common Ag transfectants that include exon B-encoded sequences, such as AB and B, but not with those that also include C-encoded sequences, such as ABC or BC. It can be concluded that MT3 recognizes additional heterogeneity in the leukocyte common Ag complex, that is based on the differential expression of sialic acid-dependent determinants associated with exon B-encoded sequences.
Unusual Glycosaminoglycans from a Deep Sea Hydrothermal Bacterium Improve Fibrillar Collagen Structuring and Fibroblast Activities in Engineered Connective Tissues (2013)

Biopolymers produced by marine organisms can offer useful tools for regenerative medicine. Particularly, HE800 exopolysaccharide (HE800 EPS) secreted by a deep-sea hydrothermal bacterium displays an interesting glycosaminoglycan-like feature resembling hyaluronan. Previous studies demonstrated its effectiveness to enhance in vivo bone regeneration and to support osteoblastic cell metabolism in culture. Thus, in order to assess the usefulness of this high-molecular weight polymer in tissue engineering and tissue repair, in vitro reconstructed connective tissues containing HE800 EPS were performed. We showed that this polysaccharide promotes both collagen structuring and extracellular matrix settle by dermal fibroblasts. Furthermore, from the native HE800 EPS, a low-molecular weight sulfated derivative (HE800 DROS) displaying chemical analogy with heparan-sulfate, was designed. Thus, it was demonstrated that HE800 DROS mimics some properties of heparan-sulfate, such as promotion of fibroblast proliferation and inhibition of matrix metalloproteinase (MMP) secretion. Therefore, we suggest that the HE800EPS family can be considered as an innovative biotechnological source of glycosaminoglycan-like compounds useful to design biomaterials and drugs for tissue engineering and repair.
ChemInform Abstract: Oscillatory Interlayer Exchange and Giant Magnetoresistance in Magnetic Multilayers (1997)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A wearable artificial kidney for patients with end-stage renal disease (2016)

The Wearable Artificial Kidney Foundation and Blood Purification Technologies Inc.
Soft forwarding device cooperation strategies for 5G radio access networks (2014)

Device-to-device (D2D) connectivity is likely to represent a major enabling technology for future fifth generation (5G) radio access networks. In this paper, we introduce a new model for device cooperation in 5G radio access networks termed frequency-selective soft forwarding (FSSF). FSSF is based on soft-combining by a target user equipment (TUE) of selectively forwarded soft information data by a set of cooperating user equipments (CUEs) acting as mobile relays towards the TUE. FSSF exploits the inherent frequency selectivity and broadcast nature of the downlink radio access channel for the sake of enabling efficient device cooperation and seamless integration of D2D connectivity into cellular radio access networks. Several variants of FSSF are investigated, including centralized and distributed approaches, thus offering various tradeoffs of performance versus signaling overhead cost. Exhaustive simulation results using a state-of-the-art long-term evolution (LTE)-compliant link-level simulator show that FSSF well outperforms baseline device cooperation schemes relying on conventional decode-and-forward (DF) relaying and approaches the performance of optimal joint reception with significantly lower cost in terms of D2D resource utilization and signaling overhead.
Towards On-Chip Optical FFTs for Convolutional Neural Networks (2017)

Convolutional neural networks have become an essential element of spatial deep learning systems. In the prevailing architecture, the convolution operation is performed with Fast Fourier Transforms (FFT) electronically in GPUs. The parallelism of GPUs provides an efficiency over CPUs, however both approaches being electronic are bound by the speed and power limits of the interconnect delay inside the circuits. Here we present a silicon photonics based architecture for convolutional neural networks that harnesses the phase property of light to perform FFTs efficiently. Our all-optical FFT is based on nested Mach-Zender Interferometers, directional couplers, and phase shifters, with backend electro-optic modulators for sampling. The FFT delay depends only on the propagation delay of the optical signal through the silicon photonics structures. Designing and analyzing the performance of a convolutional neural network deployed with our on-chip optical FFT, we find dramatic improvements by up to 10^3 when compared to state-of-the-art GPUs when exploring a compounded figure-of-merit given by power per convolution over area. At a high level, this performance is enabled by mapping the desired mathematical function, an FFT, synergistically onto hardware, in this case optical delay interferometers.
Insulin infusion amplifies 17 alpha-hydroxycorticosteroid intermediates response to adrenocorticotropin in hyperandrogenic women: apparent relative impairment of 17,20-lyase activity. (1996)

Recent data suggest that insulin is a modulator of ovarian and adrenal steroidogenesis and that, in the ovary of hyperandrogenic women, hyperinsulinemia might cause dysregulation of cytochrome P450c17 alpha activity. To further assess in vivo the effects of insulin on adrenal steroidogenesis, ACTH stimulation was carried out in 21 hyperandrogenic women during a 3-h hyperinsulinemic (80 mU/m2-min) euglycemic clamp. In all of these women the procedure was repeated during saline infusion as n control. In nonamenorrheic patients, the tests were performed in the early follicular phase of two different menstrual cycles. Serum cortisol, progesterone, 17-hydroxypregnenolone (17-OHJPREG). 17-hydroxyprogesterone (17-OHP), dehydroepiandrosterone (DHEA), and androstenedione (A) were measured after 2 h of insulin or saline infusion (zero time) and, subsequently, 30 and 60 min after an iv bolus of 0.25 mg ACTH-(1-24). At zero time, no difference was found in the serum steroid concentrations between the two protocols. ACTH-stimulated serum 17-OHPREG and, to a lesser extent, 17-OHP were significantly higher during insulin than during saline infusion (peaks, 60.6 +/- 9.0 vs. 40.7 +/- 7.9 and 7.7 +/- 7.7 vs. 6.6 +/- 0.6 nmol/L; P < 0.005 and P < 0.01, respectively). Serum DHEA was also slightly higher during hyperinsulinemia, although only after 30 min (54.5 +/- 3.0 vs. 48.2 +/- 4.2 nmol/L; P < 0.05). No statistically significant difference in the cortisol, progesterone, or androstenedione response to ACTH was found between the two protocols. ACTH-stimulated 17-OHPREG/DHEA and 17-OHP/A molar ratios, indexes of apparent 17,20-lyase activity, were significantly higher during the clamp studies than during saline infusion (by ANOVA, F = 12.8; P < 0.001 and F = 6.7; P < 0.005, respectively), suggesting an impaired enzyme activity. These in vivo data support the hypothesis that insulin potentiates ACTH-stimulated steroidogenesis. This effect of insulin seems to be associated with a relative impairment of 17,20-lyase activity.
Customized Nonlinear Bandits for Online Response Selection in Neural Conversation Models (2018)

Dialog response selection is an important step towards natural response generation in conversational agents. Existing work on neural conversational models mainly focuses on offline supervised learning using a large set of context-response pairs. In this paper, we focus on online learning of response selection in retrieval-based dialog systems. We propose a contextual multi-armed bandit model with a nonlinear reward function that uses distributed representation of text for online response selection. A bidirectional LSTM is used to produce the distributed representations of dialog context and responses, which serve as the input to a contextual bandit. In learning the bandit, we propose a customized Thompson sampling method that is applied to a polynomial feature space in approximating the reward. Experimental results on the Ubuntu Dialogue Corpus demonstrate significant performance gains of the proposed method over conventional linear contextual bandits. Moreover, we report encouraging response selection performance of the proposed neural bandit model using the Recall@k metric for a small set of online training samples.
Clinical Use of the Q‐Switched Ruby and the Q‐Switched Nd:YAG (1064 nm and 532 nm) Lasers for Treatment of Tattoos (1993)

Q-switched lasers can remove tattoos without residual scarring. Efficacy of ink removal is dependent on the wavelength used for the targeted pigment.
Necessary and sufficient conditions for optimal flow control in multirate multicast networks (2003)

The authors consider the optimal flow control problem in multirate multicast networks where all receivers of the same multicast group can receive service at different rates with different QoS. The objective is to achieve the fairness transmission rates that maximise the total receiver utility under the capacity constraint of links. They first propose necessary and sufficient conditions for the optimal solution to the problem, and then derive a new optimal flow control strategy using the Lagrangian multiplier method. Like the unicast case, the basic algorithm consists of a link algorithm to update the link price, and a receiver algorithm to adapt the transmission rate according to the link prices along its path. In particular if some groups contain only one receiver and become unicast, the algorithm will degrade to their previously proposed unicast algorithm.
The Initial Appearance of Lung Adenocarcinoma on Computed Tomography. (2002)

目的・方法. 外科的に切除された肺腺癌で, 過去約2年以上の経過がCT画像で追跡可能であった17症例について, 肺癌と認識しうる初回のCT画像所見 (初回CT像) および画像の経時的変化に関する検討を行った. 結果. 初回CT像は,(1) 淡い濃度上昇が主体のすりガラス (ground-glass opacity, 以下GGO) 様陰影,(2) 内部に複数の細気管支透亮像を有する浸潤影 (bubble-like appearance, 以下BLA) 様陰影,(3) 孤立性小結節 (以下nodule) 様陰影,(4) 瘢痕 (以下scar) 様陰影, の4所見に分類された. 病変陰影への血管の関与, 内部の気管支透亮像, 胸膜陥入の所見はいずれも, 初回CT像に比較して術前CT画像で認められる頻度が増加していた. 血管の関与は, 初回CT像で, 他の所見に比較し最も高頻度に認められた. GGO様陰影では, 経過中に内部に濃度上昇域が出現し, その後陰影が増大する症例を認めた. 病変陰影の最大径の増大様式は,(1) 緩徐な増大,(2) 急速な増大,(3) 初期は緩徐で後に増大速度が増加, の3様式に分類可能であった. 増大様式やdoubiing timeの検討により, GGO・BLA様陰影は6～12ケ月, nodule様陰影は2～3ケ月の経過観察期間が適切であると推察された. 結論. 肺腺癌は初回CT像により, 病変径の増大様式やdoubling timeに特徴を認めることが示された.
Automatic Pain Recognition from Video and Biomedical Signals (2014)

How much does it hurt? Accurate assessment of pain is very important for selecting the right treatment, however current methods are not sufficiently valid and reliable in many cases. Automatic pain monitoring may help by providing an objective and continuous assessment. In this paper we propose an automatic pain recognition system combining information from video and biomedical signals, namely facial expression, head movement, galvanic skin response, electromyography and electrocardiogram. Using the BioVid Heat Pain Database, the system is evaluated in the task of pain detection showing significant improvement over the current state of the art. Further, we discuss the relevance of the modalities and compare person-specific and generic classification models.
Water-Stable Lithium Anode with the Three-Layer Construction for Aqueous Lithium–Air Secondary Batteries (2009)

A water-stable multilayer Li-metal electrode consisting of a lithium metal, a PEO(18)LiN(SO(2)CF(3))(2)-BaTiO(3) composite polymer, and a lithium-conducting glass ceramic Li(1.35)Ti(1.75)Al(0.25)P(0.9)Si(0.1)O(12) (LTAP) was proposed as the lithium anode for aqueous lithium-air secondary batteries. The addition of finely dispersed nanosize BaTiO(3) in the polymer electrolyte greatly reduced the interfacial resistance between the Li anode and the polymer electrolyte. A Li/PEO(18)LiN(SO(2)CF(3))(2)-10 wt % BaTiO(3)/LTAP electrode showed a total resistance of 175 Omega cm(2) in a 1 M aqueous LiCl solution at 60 degrees C, with no change in the electrode resistance over a month. The Li/PEO(18)LiN(SO(2)CF(3))(2)-10 wt % BaTiO(3)/LTAP/aqueous 1 M LiCl/Pt air cell had a stable open-circuit voltage of 3.80 V, which was equivalent to that calculated from the cell reaction of 2Li+1/2O(2)+H(2)O=2LiOH. The cell exhibited a stable and reversible discharge/charge performance of 0.5 mA cm(-2) at 60 degrees C, suggesting excellent reversibility of the lithium oxidation reduction reaction for the Li/PEO(18)LiN(SO(2)CF(3))(2)-10 wt % BaTiO(3)/LTAP electrode.
EP300 single nucleotide polymorphism rs20551 correlates with prolonged overall survival in diffuse large B cell lymphoma patients treated with R-CHOP (2017)

This study suggests that EP300 SNP rs20551 might be a useful biomarker to predict the long-term outcome of R-CHOP in DLBCL patients.
Porphyromonas gingivalis Mediated Periodontal Disease and Atherosclerosis:Disparate Diseases with Commonalities in Pathogenesis Through TLRs (2007)

Toll-like receptors (TLRs) are a group of pathogen-associated molecular pattern receptors, which play an important role in innate immune signaling in response to microbial infection. It has been demonstrated that TLRs are differentially up regulated in response to microbial infection and chronic inflammatory diseases such as atherosclerosis. Furthermore hyperlipidemic mice deficient in TLR2, TLR4, and MyD88 signaling exhibit diminished inflammatory responses and decreased atherosclerosis. Accumulating evidence has implicated specific infectious agents including the periodontal disease pathogen Porphyromonas gingivalis in the progression of atherosclerosis. Evidence in humans suggesting that periodontal infection predisposes to atherosclerosis is derived from studies demonstrating that the periodontal pathogen P. gingivalis resides in the wall of atherosclerotic vessels and seroepidemiological studies demonstrating an association between pathogen-specific IgG antibodies and atherosclerosis. We have established that the inflammatory signaling pathways that P. gingivalis utilizes is dependent on the cell type and this specificity clearly influences innate immune signaling in the context of local and distant chronic inflammation induced by this pathogen. We have demonstrated that P. gingivalis requires TLR2 to induce oral inflammatory bone lose in mice. Furthermore, we have demonstrated that P. gingivalis infection accelerates atherosclerosis in hyperlipidemic mice with an associated increase in expression of TLR2 and TLR4 in atherosclerotic lesions. Our recent work with P. gingivalis has demonstrated the effectiveness of specific intervention strategies (immunization) in the prevention of pathogen-accelerated atherosclerosis. Improved understanding of the mechanisms driving infection, and chronic inflammation during atherosclerosis may ultimately provide new targets for therapy.
Synthesis of 1-Substituted 3-(Chloromethyl)-6-aminoindoline (6-Amino-<i>seco</i>-CI) DNA Minor Groove Alkylating Agents and Structure−Activity Relationships for Their Cytotoxicity (1999)

A series of racemic 6-amino-seco-cyclopropylindole (seco-CI) compounds was prepared by coupling 1-(tert-butyloxycarbonyl)-3-(chloromethyl)-6-nitroindoline with appropriate acids, followed by nitro group reduction, and evaluated for cytotoxicity in AA8, UV4, EMT6, and SKOV3 cell lines. These compounds are of interest due to their close structural relationship to known AT-specific alkylating agents and cytotoxins and also for the possible construction of stable amine-based prodrugs designed for tumor-specific release. Variations included indole or furan side chains with different substituents, sulfonamide or carboxamide linkers, extension of the minor groove binding side chain to two subunits, and the use of a pyrroylacryloyl unit previously reported to give extremely potent analogues. The parent compound, with a trimethoxyindole side chain, was a moderately potent cytotoxin (IC50 = 0.34 microM in AA8 cells, 4 h exposure). A single 5-methoxy group on the indole minor groove binding unit was sufficient to maintain potency, and a series of dimethylaminoethoxy-substituted analogues retained the cytotoxicity of the parent compound, while providing increased aqueous solubility.
Carbon quantum dots and their applications (2014)

Fluorescent carbon nanoparticles or carbon quantum dots (CQDs) are a new class of carbon nanomaterials that have emerged recently and have garnered much interest as potential competitors to conventional semiconductor quantum dots. In addition to their comparable optical properties, CQDs have the desired advantages of low toxicity, environmental friendliness low cost and simple synthetic routes. Moreover, surface passivation and functionalization of CQDs allow for the control of their physicochemical properties. Since their discovery, CQDs have found many applications in the fields of chemical sensing, biosensing, bioimaging, nanomedicine, photocatalysis and electrocatalysis. This article reviews the progress in the research and development of CQDs with an emphasis on their synthesis, functionalization and technical applications along with some discussion on challenges and perspectives in this exciting and promising field.
Strategic Analysis Using Actual and Potential Competiveness (1992)

The traditional approach to strategic planning at the level of the firm, involving targets for profitability, quantitative forecasts, gap‐closing strategic‐moves (cost reduction, strategic investments etc.) and finally implementation or resource‐ deployment, has often been criticised on both practical and philosophical grounds. Perhaps one of the best known critiques of this conventional approach is the article by Hayes (1985). He suggests that competent strategic management of the firm in today's competitive environment in fact involves a complete reversal of the underlying “goals‐ways‐means” sequence of traditional planning, so that the principle task of strategic managers now becomes first the creation of a competent organisation (i.e. means) in which the fullest possible potential of all resources is realised. Only then, it is argued, can a coherent strategy (ways) and strategic vision (ends) really emerge in practice.
New security mechanisms for network time synchronization protocols (2017)

As evolving security concerns have prevailed, the network time synchronization protocol community has been actively engaged in the development of improved security mechanisms for both the IEEE 1588 Precision Time Protocol (PTP) and the IETF Network Time Protocol (NTP). These activities have matured to the point where this year should see the finalization of the first new security mechanisms for time protocols in ten years. This paper provides an overview of the two solutions being developed, compares and contrasts those solutions, and discusses relevant use cases and deployment scenarios.