gebhart/patrepeval huggingface dataset:
Quality prediction for image completion (2012)

We present a data-driven method to predict the quality of an image completion method. Our method is based on the state-of-the-art non-parametric framework of Wexler et al . [2007]. It uses automatically derived search space constraints for patch source regions, which lead to improved texture synthesis and semantically more plausible results. These constraints also facilitate performance prediction by allowing us to correlate output quality against features of possible regions used for synthesis. We use our algorithm to first crop and then complete stitched panoramas. Our predictive ability is used to find an optimal crop shape before the completion is computed, potentially saving significant amounts of computation. Our optimized crop includes as much of the original panorama as possible while avoiding regions that can be less successfully filled in. Our predictor can also be applied for hole filling in the interior of images. In addition to extensive comparative results, we ran several user studies validating our predictive feature, good relative quality of our results against those of other state-of-the-art algorithms, and our automatic cropping algorithm.
Sequence homology between tetanus and botulinum toxins detected by an antipeptide antibody (1989)

The extent of immunological similarity between tetanus toxin and botulinum toxins A, B, C1, and E was studied by using 10 antibodies produced against synthetic peptides representing different sequences of tetanus toxin, mouse antitetanus serum, and human Tetanus Immune Globulin. Antibodies produced against the synthetic peptides recognized tetanus toxin in an enzyme-linked immunosorbent assay and on Western blots (immunoblots) but did not appear to recognize the native protein. One of the antitetanus peptide antibodies, which was produced against a peptide from the amino terminal, cross-reacted with three of the four botulinum toxins on immunoblots. This antibody, 1, reacted strongly with botulinum toxins B and C1 and weakly with E but did not recognize type A toxin. None of the other peptide antibodies cross-reacted with the botulinum toxins. Mouse antitetanus serum and human Tetanus Immune Globulin did not recognize any of the botulinum toxins on immunoblots. The amino-terminal region of the light chain of tetanus toxin and botulinum toxin types A, B, C1, and E are known to have sequence homology. Our data demonstrate that for tetanus toxin and botulinum toxin types B, C1, and E this region also has immunological homology. Type A, which has the least amount of homology with tetanus toxin in this region, does not share this immunological homology. These data also suggest that although the native structures of tetanus and botulinum toxins have relatively few common immunological determinants, the two toxins may contain short stretches of identical or very similar amino acid sequences.
Transient receptor potential A1 mediates acetaldehyde‐evoked pain sensation (2007)

Six transient receptor potential (TRP) ion channels expressed in the sensory afferents play an important role as body thermosensors and also as peripheral pain detectors. It is known that a number of natural compounds specifically activate those sensory neuronal TRP channels, and a well-known example is cinnamaldehyde for TRPA1. Here we show that human and mouse TRPA1 are activated by acetaldehyde, an intermediate substance of ethanol metabolism, in the HEK293T cell heterologous expression system and in cultured mouse trigeminal neurons. Acetaldehyde failed to activate other temperature-sensitive TRP channels expressed in sensory neurons. TRPA1 antagonists camphor and gadolinium, and a general TRP blocker ruthenium red inhibited TRPA1 activation by acetaldehyde. Camphor, gadolinium and ruthenium red also suppressed the acute nociceptive behaviors induced by the intradermal administration of acetaldehyde into the mouse footpads. Intradermal co-application of prostaglandin E2 and acetaldehyde greatly potentiated the acetaldehyde-induced nociceptive responses, and this effect was reversed by treatment with the TRPA1 antagonist camphor. These results suggest that acetaldehyde causes nociception via TRPA1 activation. Our data may also help elucidate the mechanisms underlying acetaldehyde-related pathological symptoms such as hangover pain.
An adaptive protection circuit for power amplifier ruggedness improvement (2005)

The paper presents a novel protection circuit for power amplifier (PA) ruggedness improvement. This protection circuit is a monolithically integrated, cost and size effective, collector current limiter, indexed to the supply voltage. Compared with conventional protection circuits, the current threshold is indexed to the supply voltage and the protection circuitry uses the same type of device as the RF power transistor to be protected, making it very easy to integrate and more robust to process variations. Moreover, the circuit efficiently protects the PA from all mismatch conditions. The experimental results show that the PA ruggedness is improved (standing wave ratio up to 10:1 for all phases with a supply voltage up to 5.5 V) while maintaining the output power and power-added efficiency under a 50 ohm load.
Ultra-high throughput detection (1 million droplets per second) of fluorescent droplets using a cell phone camera and time domain encoded optofluidics (2017)

Droplet-based assays-in which ultra-sensitive molecular measurements are made by performing millions of parallel experiments in picoliter droplets-have generated enormous enthusiasm due to their single molecule resolution and robustness to reaction conditions. These assays have great untapped potential for point of care diagnostics but are currently confined to laboratory settings due to the instrumentation necessary to serially generate, control, and measure tens of millions of droplets. To address this challenge, we have developed the microdroplet megascale detector (μMD) that can generate and detect the fluorescence of millions of droplets per second (1000× faster than conventional approaches) using only a conventional cell phone camera. The key innovation of our approach is borrowed from the telecommunications industry, wherein we modulate the excitation light with a pseudorandom sequence that enables individual droplets to be resolved that would otherwise overlap due to the limited frame rate of digital cameras. Using this approach, the μMD measures droplets at a rate of 10<sup>6</sup> droplets per sec (ϕ = 166 mL h<sup>-1</sup>) in 120 parallel microfluidic channels and achieves a limit of detection LOD = 1 μM Rhodamine dye, sufficient for typical droplet based assays. We incorporate this new droplet detection technology with our previously reported parallelized droplet production strategy, incorporating 200 parallel droplet makers and only one set of continuous and droplet phase inputs and one output line. By miniaturizing and integrating droplet based diagnostics into a handheld format, the μMD platform can translate ultra-sensitive droplet based assays into a self-contained platform for practical use in clinical and industrial settings.
High temperature fiber optic laser-induced breakdown spectroscopy sensor for analysis of molten alloy constituents (2002)

A fiber optic (FO) laser-induced breakdown spectroscopy (LIBS) sensor that measures the on-line, in situ elemental composition of a molten alloy inside the melt in a furnace is described. This sensor has applications as a process monitor and control tool for glass, aluminum, and steel melters. The sensor is based on the transmission of laser energy through a multimode optical fiber. The laser radiation from the fiber is collimated and finally focused inside the aluminum melt in the furnace by a specially designed stainless steel holder that holds the collimating and focusing lens. Atomic emission from sparks from the laser plasma is collected by the same stainless steel lens holder and transmitted back through the optical fiber and finally fed into the entrance slit of the spectrograph. The present design of the stainless steel holder is useful for obtaining a collimated LIBS signal over a long distance (the distance between the focusing and collimated lenses is more than 200 cm). Parametric studies such as sample-to-lens distance and the effect of the angle of incidence of the laser beam on the sample surface were performed. Calibration curves for minor elements were obtained for solid Al alloys as well as for a molten Al alloy in the laboratory furnace by inserting the FO LIBS probe inside the molten material. The performance of the probe was also tested by inserting the stainless steel holder into the melt at a 45° angle, which is necessary for collecting LIBS data in an industrial furnace. LIBS spectra in different spectral regions were recorded in the pilot furnace during different tests where known amounts of minor elements were added to the melt. The results obtained from this sensor for different Al alloys demonstrate the usefulness of this sensor to monitor the concentration of different constituents of the molten Al alloy in an industrial furnace.
Method For The Production Of ?-linolenic Acid And/or Stearidonic Acid In Transgenic Brassicaceae And Linaceae (Patent WO 2007/051577 A2) (2007)

The invention relates to the production of ?-linolenic acid (18:3 <SUP>?6,9,12</SUP>) or stearidonic acid (18:4 <SUP>?6,9,12,15</SUP>) or ?-linolenic acid (18:3<SUP>?6,9,12</SUP>) and stearidonic acid (18:4 <SUP>?6,9,12,15</SUP>) in transgenic plants of the brassicaceae family, said transgenic plants containing at least 10 percent by weight of oleic acid relative to the total fatty acid concentration and being provided with an increased ?-6-C<SUB>18</SUB> fatty acid concentration as a result of the activity of the ?-6 desaturases used in the method. The invention also relates to novel nucleic acid sequences coding for the ?-6 desaturases used in the method, gene constructs containing said nucleic acid sequences, a vector and transgenic plants containing at least one nucleic acid sequence or a gene construct.
A Pictorial Tracking of Basal Plane Dislocations in SiC Epitaxy (2010)

The recently developed technique of UVPL imaging has been used to track the path of basal plane dislocations (BPDs) in SiC epitaxial layers. The glide of BPDs during epitaxial growth has been observed and the role of this glide in forming half-loop arrays has been examined. The ability to track the path of BPDs through the epitaxy has made it possible to develop a BPD reduction process for epitaxy grown on 8° offcut wafers, which uses an in situ growth interrupt and has achieved a BPD reduction of > 98%. The images also provide insight into the strong BPD reduction that typically occurs in epitaxy grown on 4° offcut wafers.
Crystallization and preliminary X-ray crystallographic studies of type A influenza virus matrix protein M1 (1997)

The matrix protein, M1, of influenza virus strain A/PR/8/34 has been purified from virions and crystallized. The crystals consist of a stable fragment (18 kDa) of the M1 protein. X-ray diffraction studies indicated that the crystals are in space group P3(1)21 or P3(2)21, with a = 66.17, c = 135.30 A. V(m) calculations showed that there are two monomers in the asymmetric unit.
Larvicidal and Biting Deterrent Activity of Essential Oils of<i>Curcuma longa</i>,<i>Ar</i>-turmerone, and Curcuminoids Against<i>Aedes aegypti</i>and<i>Anopheles quadrimaculatus</i>(Culicidae: Diptera) (2015)

Journal Article Larvicidal and Biting Deterrent Activity of Essential Oils of Curcuma longa, Ar-turmerone, and Curcuminoids Against Aedes aegypti and Anopheles quadrimaculatus (Culicidae: Diptera) Get access Abbas Ali, Abbas Ali 2 1National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, MS 38677. 2Corresponding author, e-mail: aali@olemiss.edu. Search for other works by this author on: Oxford Academic PubMed Google Scholar Yan-Hong Wang, Yan-Hong Wang 1National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, MS 38677. Search for other works by this author on: Oxford Academic PubMed Google Scholar Ikhlas A. Khan Ikhlas A. Khan 1National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, MS 38677.3Department of BioMolecular Sciences, School of Pharmacy, The University of Mississippi, University, MS 386774Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh 11451 Saudi Arabia Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Medical Entomology, Volume 52, Issue 5, September 2015, Pages 979–986, https://doi.org/10.1093/jme/tjv072 Published: 23 June 2015 Article history Received: 03 March 2015 Accepted: 26 May 2015 Published: 23 June 2015
Power fingerprinting in SDR &#x00026; CR integrity assessment (2009)

Integrity assessment plays a critical role in the security and regulatory certification of software-defined radio (SDR) and cognitive radio (CR). We propose a novel approach to assess the execution status of SDR and CR by monitoring their dynamic power consumption. The approach relies on extracting distinctive power consumption signatures, or fingerprints, and then using pattern recognition techniques to determine if they match expected behavior. This approach provides an external, independent monitor for assessing the integrity of SDR and CR. Feasibility experiments are encouraging and show the correct identification of basic software routines using discriminatory features extracted from the time domain.
Enhance of Tumor Targeting by Receptor-Mediated Endocytosis Using Low Molecular Water-Soluble Chitosan Nanoparticles Loaded with Anticancer Agent (2007)

In this study, we prepared using low molecular weight water-soluble chitosan nanoparticle loaded paclitaxel (LMWSC-NPT) and investigated the potential as a drug carrier which is able to accumulate in the tumor site. In the experiment of receptor-mediated endocytosis, LMWSC-NPT was treated with sodium azid (NaN3) as an inhibitor of endocytosis process. As results, the antitumor activity of LMWSC-NPT treated with sodium azid didn’t show but LMWSC-NPT was shown the high antitumor activity. Therefore, LMWSC-NPs modified with hydrophobic group will be useful anticancer agent carrier via receptor-mediated endocytosis.
Dynamics of fiber optical parametric chirped pulse amplifiers (2011)

We numerically and experimentally investigate the complete dynamics of the amplification process occurring in fiber optical parametric chirped pulse amplifiers. We show that, in the linear amplification regime, more than 30% of the pump can be converted into the signal with a very good temporal contrast higher than 65 dB. Under strong saturation, this efficiency is kept constant but the temporal contrast of the signal significantly degrades.
Gene transfer to brain using herpes simplex virus vectors (1994)

Herpes simplex virus type 1 represents an ideal candidate for development as a vehicle for gene transfer to postmitotic neurons of the central nervous system. The natural biology of this virus makes it well suited for this purpose as it is capable of infecting a variety of neuronal cell types in the brain where the viral genome can persist indefinitely in a latent state. In latency, the viral lytic genes are transcriptionally silent and a unique set of latency-associated transcripts are expressed. Two impediments to using herpes simplex virus vectors must be overcome: (1) A noncytotoxic mutant virus backbone must be engineered, and (2) a suitable promoter-regulator that stably expresses foreign genes from the vector genome during latency must be constructed. Deletion of specific immediate early genes from the vector can render the virus nontoxic to neurons in culture and in vivo following stereotactic inoculation into specific regions of the brain. Because these viruses cannot replicate, they enter latency on infection of central nervous system neurons. A number of viral and cellular promoters have been tested for their ability to express genes during latency. Strong viral promoters and neurospecific promoters display transient activity. Although the promoter regions for the latency-associated transcripts are highly active in the peripheral nervous system, they show low-level but persistent activity in the brain. Experiments are in progress to exploit RNA polymerase III gene promoters or novel recombinant promoters capable of auto-inducing their own expression in order to increase gene expression during latency in brain neurons.
Effect of 1‐Methylcyclopropene on the Quality of Fresh‐cut Apple Slices (2003)

ABSTRACT: The objective of this project was to treat fresh‐cut apple slices with the ethylene inhibitor 1‐methylcyclopropene (1‐MCP) to retard ethylene‐induced deterioration and senescence and to prolong the shelf life of such products. Intact Braeburn and Pacific Rose apples were treated at different times with 1‐MCP, cut, and stored at 0 °C. Samples were analyzed initially and then weekly for ethylene, respiration, flesh firmness, tissue color, titratable acidity, and soluble solids content during 5 wk of storage. 1‐MCP treatment was effective in reducing ethylene production, respiration, and loss of firmness and color of slices when applied to whole apples directly after harvest. Total sugar and acidity levels were not affected significantly.
Scanning superconducting quantum interference device susceptometry (2001)

We report a scanning superconducting quantum interference device (SQUID) microsusceptometer with a spatial resolution of 8 μm, tested by measuring the susceptibility of individual 3 μm diam tin disks. Images of the disks agree well with numerical modeling based on the known geometry of the SQUID microsusceptometers. The low-field spin sensitivity between 1.5 and 6 K is 1×105 μB/Hz while scanning.
Galectin-3 Interacts with the CHI3L1 Axis and Contributes to Hermansky–Pudlak Syndrome Lung Disease (2018)

Hermansky-Pudlak syndrome (HPS) comprises a group of inherited disorders caused by mutations that alter the function of lysosome-related organelles. Pulmonary fibrosis is the major cause of morbidity and mortality in HPS-1 and HPS-4 patients. However, the mechanisms that underlie the exaggerated injury and fibroproliferative repair responses in HPS have not been adequately defined. In particular, although Galectin-3 (Gal-3) is dysregulated in HPS, its roles in the pathogenesis of HPS have not been adequately defined. In addition, although chitinase 3-like 1 (CHI3L1) and its receptors play major roles in the injury and repair responses in HPS, the ability of Gal-3 to interact with or alter the function of these moieties has not been evaluated. In this article, we demonstrate that Gal-3 accumulates in exaggerated quantities in bronchoalveolar lavage fluids, and traffics abnormally and accumulates intracellularly in lung fibroblasts and macrophages from bleomycin-treated pale ear, HPS-1-deficient mice. We also demonstrate that Gal-3 drives epithelial apoptosis when in the extracellular space, and stimulates cell proliferation and myofibroblast differentiation when accumulated in fibroblasts and M2-like differentiation when accumulated in macrophages. Biophysical and signaling evaluations also demonstrated that Gal-3 physically interacts with IL-13Rα2 and CHI3L1, and competes with TMEM219 for IL-13Rα2 binding. By doing so, Gal-3 diminishes the antiapoptotic effects of and the antiapoptotic signaling induced by CHI3L1 in epithelial cells while augmenting macrophage Wnt/β-catenin signaling. Thus, Gal-3 contributes to the exaggerated injury and fibroproliferative repair responses in HPS by altering the antiapoptotic and fibroproliferative effects of CHI3L1 and its receptor complex in a tissue compartment-specific manner.
<title>Direct optical phase shifter for phased-array systems</title> (1991)

An all optical circuit in GaAs/AlGaAs for control of phased-array systems using a single photonic integrated circuit chip has the potential for high performance control of phased-array system from a small, lightweight, package. Such a circuit based exclusively on combinations of reverse-biased optical phase modulators, waveguide interconnects, corner reflectors, and power splitter combiners with optical-fiber output to the antenna elements has been designed at Sandia National Laboratories. This paper presents some basic features of optical phase modulators for photonic circuit applications and provide relevant performance data as achieved to date. Current structures have been shown to operate with a 76.5 degree/V-mm figure of merit at 1.06 micron and losses as low as 2/cm. A digital phase shifter to allow direct digital control of phased arrays is also proposed and demonstrated.
5PM: Secure pattern matching (2013)

In this paper we consider the problem of secure pattern matching that allows single-character wildcards and substring matching in the malicious (stand-alone) setting. Our protocol, called 5PM, is executed between two parties: Server, holding a text of length n, and Client, holding a pattern of leng th m to be matched against the text, where our notion of matching is more general than traditionally considered and includes non-binary alphabets, non-binary Hamming distance and non-binary substring matching. 5PM is the first secure expressive pattern matching protocol designed to optimize round complexity by carefully specifying the entire protocol round by round. 5PM requires only eight rounds in the malicious (static corruptions) model. In the malicious model, 5PM requires O((m+n)k2) communication complexity and O(m+n) encryptions, where m is the pattern length and n is the text length. Further, 5PM can hide pattern size with no asymptotic additional costs in either computation or bandwidth.
Organic Electroluminescent Devices Using a Mixed Single Layer (1994)

Electroluminescent devices with mixed single-layer organic materials that consist of hole transport meterial, electron transport material and dopant material are studied. High luminance could be obtained by optimizing the weight ratios of hole and electron transport materials.
<i>In Vitro</i>Studies on Reuterin Synthesis by<i>Lactobacillus reuteri</i> (1989)

Lactobacillus reuteri resides in the gastrointestinal ecosystem of humans and other animals. In an earlier report we showed that this enteric species converts glycerol into reuterin-a substance with broad-spectrum antibacterial activity. In this report we show that reuterin also has antimycotic and antiprotozoal activity. A minimum inhibitory concentration (MIC) assay was developed and used to study the conditions under which reuterin is synthesised. The results show reuterin to be synthesised in vitro under pH, temperature and relative anaerobic conditions similar to those believed to exist in the regions of the gastrointestinal ecosystem inhabited by L. reuteri . It was also demonstrated that L. reuteri cells are stimulated to produce reuterin when permitted to interact directly with a variety of other microorganisms. A symbiotic relationship between L. reuteri and its host is postulated and discussed. Keywords: Lactobacillus reuteri ; Reuterin; Antimicrobial substance; Symbiont.
Histological validation of a type 1 diabetes clinical diagnostic model for classification of diabetes (2020)

Our study provides robust histological evidence that a clinical diagnostic model, combining clinical features and biomarkers, could improve diabetes classification. Our study also provides reassurance that a C-peptide-based definition of type 1 diabetes is an appropriate surrogate outcome that can be used in large clinical studies where histological definition is impossible. Parts of this study were presented in abstract form at the Network for Pancreatic Organ Donors Conference, Florida, USA, 19-22 February 2019 and Diabetes UK Professional Conference, Liverpool, UK, 6-8 March 2019.