gebhart/patrepeval huggingface dataset:
A non-interfering selective disassembly sequence for components with geometric constraints (2002)

Abstract This paper analyzes the problem of global disassembly of a selected component from a geometrically constrained assembly. The geometric constraints are: (i) spatial constraints due to the three-dimensional geometric interactions between the components in an assembly; and (ii) user-defined constraints, such as grouping of components as subassemblies and directional constraints on component geometry. A new algorithm has been proposed to determine a non-interfering disassembly sequence for a selected component, minimizing the number of simultaneous component removals. The algorithm analyzes both the spatial constraints of the assembly geometry and the user-defined constraints in evaluating the accessibility of components, which is followed by determining the topological disassembly ordering of the components to evaluate an optimal sequence. Preliminary implementation results of the algorithm for a geometrically constrained assembly are presented.
Design and performance of a SWaP short-range fully fibered monostatic laser rangefinder (2017)

The development of a multisensor optronic device requires Size, Weight and Power (SWaP), cost-effective and modular rangefinders while keeping a good range performance. We report on a fully fibered monostatic laser rangerfinder based on a one lens collimator used as the aperture of both the emission and reception channels. This has been possible thanks to the use of a diplexer. This design makes the system compacter and achieves a 200g system weight. In addition to its low volume, the fully fibered architecture allows designing a building block rangefinder with the collimator sub-system on one side and the laser and electronics cards module on the other side. Both are linked up by only an optical fiber. This kit format enables the rangefinder to better fit in any available space in higher level systems such as gimbals and multi-function imagers. Besides, no alignment is needed, and no parallax error is possible: the alignment between channels is guaranteed by design over the whole range. The emission/reception channels of the first prototype has a 28mm diameter 80mm focal length lens, and a 1.55μm 100μJ pulsed laser firing in a burst mode. The rangefinder is set in a class 1 configuration, and measures at 1Hz. The achieved Extinction Ratio is 30dB, which is equivalent to a range on NATO targets of 7km. The achieved ER being class 1M at 5Hz is even 32dB, which is equivalent to a range of 8.5km on NATO targets. More configurations are reported in this article with their associated performance.
High-Performance Airfoil Using Coflow Jet Flow Control (2007)

T O ACHIEVE revolutionary aircraft performance, advanced technologies should be pursued to drastically reduce the weight of aircraft and fuel consumption and significantly increase aircraft mission payload and maneuverability. Both the military and commercial aircraft will benefit from the same technology. Flow control is a promising technology to break through the limits of the conventional aerodynamic concepts. Recently, a novel active airfoil flow control concept with zero-net mass flux, the coflow jet (CFJ) airfoil, has been developed by Zha et al. [1–5]. The CFJ airfoil achieves three effects simultaneously in a dramatic fashion: lift augmentation, stall margin increase, and drag reduction. The energy expenditure of the CFJ airfoil is low [1], and the CFJ airfoil concept is straightforward to implement. The CFJ airfoil may create a new concept of an “engineless” airplane, which uses the CFJ to generate both lift and thrust without conventional propulsion systems of propellers or jet engines [6]. A CFJ airfoil [1–5] uses an injection slot near the leading edge (LE) and a suction slot near the trailing edge (TE) on the airfoil suction surface. Similar to tangential blowing, the LE jet is in the same direction of the main flow, but the same amount of mass flow that is injected is removed via suction near the TE, resulting in zeronet mass-flux flow control. A proposed fundamental mechanism [2] is that the severe adverse pressure gradient on the suction surface strongly augments turbulent mixing between the main flow and the jet [7]. The mixing then creates the lateral transport of energy from the jet to the main flow and enables the main flow to overcome the large adverse pressure gradient and remain attached at high angle of attack (AOA). The stall margin is hence significantly increased. At the same time, the high-momentum jet drastically increases the circulation, which significantly augments lift, reduces drag, or even generates thrust (negative drag). The objective of this paper is to demonstrate the high performance of the CFJ airfoil with the windtunnel test results.
Integrated control of battery energy storage management system considering PV capacity firming and energy time shift applications (2014)

This paper present a complete battery energy storage management scheme to maximize potential value that can be brought forth to medium voltage feeders. In general, the potential performance benefits produced by possible energy storage applications include improved system reliability, dynamic stability, enhanced power quality, transmission capacity enhancement and area protection. Here we propose a unique control algorithm that enhances coordination of Renewables Capacity Firming and Energy Time Shift (ETS) applications. Optimization of control parameters and set points are considered for management between the mentioned applications with the help of the proposed architecture. The design is tested on an EMTP <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">®</sup> simulation platform and the results indicates that the proposed architecture provides capability to include multiple functionality of the energy storage device maximizing the value of the energy storage in power grid.
Bioanalytical Applications and Quantum Cascade Lasers (2020)

Mid-infrared Quantum cascade lasers (QCLs) promises very high sensitivity and opens up the way for many applications in fundamental science, emission measurement and environmental monitoring. The emergence of broadband wavelength swept QCL will provide new benefits not found in FTIR and will replace it as IR-light source for the next generation of infrared analyzers.
An iPod treatment of amblyopia: an updated binocular approach. (2012)

We describe the successful translation of computerized and space-consuming laboratory equipment for the treatment of suppression to a small handheld iPod device (Apple iPod; Apple Inc., Cupertino, California). A portable and easily obtainable Apple iPod display, using current video technology offers an ideal solution for the clinical treatment of suppression. The following is a description of the iPod device and illustrates how a video game has been adapted to provide the appropriate stimulation to implement our recent antisuppression treatment protocol. One to 2 hours per day of video game playing under controlled conditions for 1 to 3 weeks can improve acuity and restore binocular function, including stereopsis in adults, well beyond the age at which traditional patching is used. This handheld platform provides a convenient and effective platform for implementing the newly proposed binocular treatment of amblyopia in the clinic, home, or elsewhere.
A novel pin-pull tester and its application on PCB pad cratering assessment (2015)

The pin-pull test is appealing because it can obtain a very high percentage of laminate cracking failures. In this paper, a pin-pull tester using a promoted soldering method is designed and manufactured. The improved pin soldering process is provided based on a method proposed in previous study. First, the requirement to form solder ball on the printed circuit board (PCB) pad is canceled, and in addition the activation flux is utilized in the material preparation step instead of applying in soldering process. Second, A solder ball on the pin is required enough weight such that the liquid solder ball can drop down from a short distance during soldering step; herein, the enough weight is defined as that the gravity of liquid solder is bigger than the upward wetting force produced by the liquid solder to the heating pin. The software for the testing procedure has been developed for the tester too. Finally, the developed pin-pull tester is utilized to assess the strength susceptibility among three types of PCB pads. Following the promoted process, the pin can be soldered on the pad easily and effectively while the flux coating is activated. The manufactured pin-pull tester, assisting with the promoted testing procedure, can perform the testing successfully. The capability to perform the pin-pull testing automatically is the unique advantage of this developed tester. The test results indicate that large number of traces attached to the pad may significantly increase the pad's strength such that resistance to the pad cratering is improved. The pin-pull tester is expected to be improved continuously, and used in many phases, such as pad designing, PCB material out quality control (OQC) & Incoming quality control (IQC) and quality control in product line.
Fabricating scaffolds by microfluidics (2009)

In this paper, we demonstrate for the first time the technique to using microfluidics to fabricate tissue engineering scaffolds with uniform pore sizes. We investigate both the bubble generation of the microfluidic device and the application of foam as a tissue engineering scaffold. Our microfluidic device consists of two concentric tapered channels, which are made by micropipettes. Nitrogen gas and aqueous alginate solution with Pluronic((R)) F127 surfactant are pumped through the inner and the outer channels, respectively. We observe rich dynamic patterns of bubbles encapsulated in the liquid droplets. The size of the bubble depends linearly on the gas pressure and inversely on the liquid flow rate. In addition, monodisperse bubbles self-assemble into crystalline structures. The liquid crystalline foams are further processed into open-cell solid foams. The novel foam gel was used as a scaffold to culture chondrocytes.
Stereospecific Ring-Opening Metathesis Polymerization (ROMP) of <i>endo</i>-Dicyclopentadiene by Molybdenum and Tungsten Catalysts (2015)

We report an examination of the ring-opening metathesis polymerization (ROMP) of endo-dicyclopentadiene (DCPD) by 10 well-defined molybdenum-based and 16 tungsten-based alkylidene initiators. Five tungsten-based MAP (monoaryloxide pyrrolide) initiators with the general formula W(X)(CHCMe2Ph)(Me2Pyr)(OAr) (X = arylimido, alkylimido, or oxo; Me2Pyr =2,5-dimethylpyrrolide; OAr = an aryloxide) were found to yield >98% cis, >98% syndiotactic poly(DCPD); they are W(N-t-Bu)(CHCMe3)(pyr)(OHMT) (2, OHMT = O-2,6-(2,4,6-Me3C6H2)2C6H3, pyr = pyrrolide), W(N-2,6-i-Pr2C6H3)(CHCMe2Ph)(pyr)(OHMT) (3), W(O)(CHCMe2Ph)(Me2Pyr)(OHMT)(PPh2Me) (7, Me2Pyr =2,5-dimethylpyrrolide), W(O)(CHCMe2Ph)(Me2Pyr)(ODFT)(PPh2Me) (9, ODFT = O-2,6-(C6F5)2C6H3), and W(O)(CHCMe2Ph)(Me2Pyr)(OTPP)(PMePh2) (10, OTPP = O-2,3,5,6-Ph4C6H). Two biphenolate alkylidene complexes, Mo(N-2,6-Me2C6H3)(CHCMe2Ph)(rac-biphen) (17) and W(N-2,6-Me2C6H3)(CHCMe2Ph)(rac-biphen) (22, biphen =3,3′-(t-Bu)2-5,5′-6,6′-(CH3)4-1,1′-biphenyl-2,2′-diolate), were found to yield >98% cis, >98% isotactic poly(DCPD). Cis, syndiotactic or cis, isotactic poly(DCPD)s (made with 50–1000 equiv of DCPD) are accessible within seconds to minutes in dichloromethane at room temperature. No isomerization or cross-linking reactions are observed, and addition of a chain transfer reagent (1-hexene) or the use of THF as a solvent does not decrease the stereospecificity of the polymerizations. Cis, syndiotactic and cis, isotactic poly(DCPD)s can be distinguished readily from each other by 13C NMR spectroscopy. Hydrogenation of each stereoregular poly(DCPD) produces H-poly(DCPD)s that have melting points near 270 °C (syndiotactic) or 290 °C (isotactic) and high crystallinities (wc = 0.83 for syndiotactic and wc = 0.74 for isotactic).
Real-time Image-based 6-DOF Localization in Large-Scale Environments (2012)

We present a real-time approach for image-based localization within large scenes that have been reconstructed offline using structure from motion (Sfm). From monocular video, our method continuously computes a precise 6-DOF camera pose, by efficiently tracking natural features and matching them to 3D points in the Sfm point cloud. Our main contribution lies in efficiently interleaving a fast keypoint tracker that uses inexpensive binary feature descriptors with a new approach for direct 2D-to-3D matching. The 2D-to-3D matching avoids the need for online extraction of scale-invariant features. Instead, offline we construct an indexed database containing multiple DAISY descriptors per 3D point extracted at multiple scales. The key to the efficiency of our method lies in invoking DAISY descriptor extraction and matching sparingly during localization, and in distributing this computation over a window of successive frames. This enables the algorithm to run in real-time, without fluctuations in the latency over long durations. We evaluate the method in large indoor and outdoor scenes. Our algorithm runs at over 30 Hz on a laptop and at 12 Hz on a low-power, mobile computer suitable for onboard computation on a quadrotor micro aerial vehicle.
Identification of citrus greening disease using a visible band image analysis (2013)

<abstract> <bold>Abstract.</bold> Huanglongbing (HLB) or citrus greening is an extremely severe disease in citrus trees which is incurable and causing a huge loss in the citrus industry in Florida. However, early detection and removal of the infected canopies may decrease spreading of the disease and avoid an enormous loss. The disease symptoms are not clear in the early stages of infection. Subjective disease detection methods such as ground scouting and other objective means are also either inaccurate or costly and time consuming. This paper introduced an easy, inexpensive, fast, and accurate method of HLB detection which is more applicable and affordable for citrus growers. A customized image acquisition system was developed to acquire images of citrus leaves (Valencia) at a waveband of 591 nm. Polarized filters were used in both illumination and imaging system to highlight the HLB disease symptoms. Several types of textural features were extracted from the leaf images and the best sets of features which could describe the infection characteristics were ranked using five different feature selection methods. The performances of seven classifiers were evaluated in a step by step classification approach. Since HLB symptoms are similar to some nutrient deficiencies, magnesium and zinc deficient samples were also included in the classification process. Healthy and HLB symptomatic samples were identified with an accuracy of 100%; however, some of the nutrient deficient samples were misclassified into other classes using this method. The overall accuracies of 86.5% and 89.6% were achieved in five-class identification and two-class (healthy or HLB) detection, respectively.
Proteasome inhibitors as therapeutics (2005)

The ubiquitin-proteasome pathway is a principle intracellular mechanism for controlled protein degradation and has recently emerged as an attractive target for anticancer therapies, because of the pleiotropic cell-cycle regulators and modulators of apoptosis that are controlled by proteasome function. In this chapter, we review the current state of the field of proteasome inhibitors and their prototypic member, bortezomib, which was recently approved by the U.S. Food and Drug Administration for the treatment of advanced multiple myeloma. Particular emphasis is placed on the pre-clinical research data that became the basis for eventual clinical applications of proteasome inhibitors, an overview of the clinical development of this exciting drug class in multiple myeloma, and a appraisal of possible uses in other haematological malignancies, such non-Hodgkin's lymphomas.
Identification and authentication of integrated circuits: Research Articles (2004)

This paper describes a technique to reliably and securely identify individual integrated circuits (ICs) based on the precise measurement of circuit delays and a simple challenge–response protocol. This technique could be used to produce key-cards that are more difficult to clone than ones involving digital keys on the IC. We consider potential venues of attack against our system, and present candidate implementations. Experiments on Field Programmable Gate Arrays show that the technique is viable, but that our current implementations could require some strengthening before it can be considered as secure. Copyright © 2004 John Wiley & Sons, Ltd.
<title>Image-intensifier-based volume tomographic angiography imaging system: work in progress</title> (1993)

The construction of the imaging system includes: (1) replacing the linear detector of the CT scanner with an image intensifier coupled to a TV camera, (2) modifying the gantry to mount the image intensifier, (3) replacing the system computer by a PC, (4) designing and constructing the interfacing and data acquisition system and (5) developing software for system control and data acquisition. The system consists of a x-ray tube and an image intensifier that are separately mounted on a gantry. The tube-detector set can be rotated over 360 degree(s) in the gantry. Two sets of images acquired with this imaging system indicate that two types of distortion occur in image intensifiers, S distortion and pincushion distortion. In the future, these two types of distortions need to be corrected prior to three-dimensional (3-D) reconstruction.
Longevity of optically activated, high gain GaAs photoconductive semiconductor switches (1998)

The longevity of high gain GaAs photoconductive semiconductor switches (PCSSs) has been extended to well over ten million pulses by reducing the density of carriers at the semiconductor to metal interface. This was achieved by reducing the density in the vertical and lateral directions. The latter was achieved by varying the spatial distribution of the trigger light thereby widening the current filaments that are characteristic of the high gain switches. We reduced the carrier density in the vertical direction by using ion implantation. These results were obtained for currents of about 10 A, current duration of 3.5 ns, and switched voltage of /spl sim/2 kV. At currents of /spl sim/70 A, the switches last for 0.6 million pulses. In order to improve the performance at high currents, new processes such as deep diffusion and epitaxial growth of contacts are being pursued. To guide this effort we recorded open shutter, infra-red images, and time-resolved Schlieren images of the current filaments, which form during high gain switching. We measured, under varying conditions, a carrier (electrons or holes) density that ranges from 3/spl times/10/sup 17/ cm/sup -3/ to 6/spl times/10/sup 18/ cm/sup -3/.
Ocean Acoustic Waveguide Remote Sensing (OAWRS) of marine ecosystems (2009)

Ocean Acoustic Waveguide Remote Sensing (OAWRS) has recently been shown to be capable of instantaneously imaging and continuously monitoring fish populations over continental shelf-scale areas, covering thousands of km 2 . We show how OAWRS can be used in a variety of oceanic ecosystems to remotely assess populations and study the behavior of fish and other marine organisms, such as Antarctic krill, to help the study of marine ecology and the ecosystem-based approach to fisheries management.
Antagonist Anti-CD40 Antibody, CHIR-12.12, Induces ADCC, Inhibits Tumor Growth, and Prolongs Survival in a Human Multiple Myeloma Xenograft Model. (2005)

Abstract CD40 is expressed on all B-cell malignancies, including multiple myeloma, and represents an attractive target for antibody therapy. CHIR-12.12 is a fully human, highly potent, IgG1 antagonistic anti-CD40 monoclonal antibody generated using XenoMouse® mice (Abgenix, Inc). CHIR-12.12 can mediate antitumor activity by at least two mechanisms: blocking CD40-ligand-mediated survival signals and killing tumor cells by antibody-dependent cellular cytotoxicity (ADCC). We have previously reported that CHIR-12.12 mediates stronger in vitro killing of CD40+- and CD20+-expressing human non-Hodgkin’s lymphoma and lymphoblastoid B cells by ADCC than rituximab and significantly inhibits the growth of rituximab-responsive (Daudi) and rituximab-resistant (Namalwa) human lymphoma and lymphoblastoid B-cell (IM-9) xenografts in vivo. In this study, we examined the in vitro and in vivo efficacy of CHIR-12.12 against the human multiple myeloma cell line KMS-12-BM. CHIR-12.12 induced lysis of KMS-12-BM cells by ADCC in a dose-dependent manner, reaching maximum cell lysis at 0.1μg/ml with an EC50 of 17.5 pM. CHIR-12.12 efficacy in vivo was evaluated in orthotopic and subcutaneous KMS-12-BM xenograft models. In the staged orthotopic model, tumor cells were delivered intravenously and treatment was initiated 7 days post cell implantation. CHIR-12.12 significantly prolonged the median survival of tumor-bearing mice in a dose-dependent manner, with a median survival of 78 and 98 days in the groups treated with 1 mg/kg and 10 mg/kg CHIR-12.12 weekly, respectively, compared to a median survival time of 68 days in the control IgG1 group (P<0.0001). Bortezomib administered i.v. twice weekly at 0.5 or 1 mg/kg showed no survival benefit. In the staged subcutaneous model, CHIR-12.12 was administered weekly at 1 and 10 mg/kg after the mean tumor volume reached 100mm3. CHIR-12.12 significantly inhibited tumor growth, with a tumor volume reduction of 42% (P<0.05) and 63% (P<0.01), respectively. Bortezomib and melphalan/prednisone did not inhibit KMS-12-BM tumor growth at the doses and schedules reported for other human multiple myeloma xenograft models. Western blot analysis and immunohistochemical staining showed significantly increased levels of cleaved PARP in KMS-12-BM s.c. tumors 7 days after the initiation of CHIR-12.12 treatment, suggesting the induction of cell death by CHIR-12.12. Taken together, these data demonstrate that the anti-CD40 mAb CHIR-12.12 has potent activity against human multiple myeloma cells in vitro and in xenograft models in vivo. Currently CHIR-12.12 is in Phase I clinical trials for the treatment of B-cell malignancies.
The relationship between perceptual disturbances in dysarthric speech and automatic speech recognition performance (2016)

State-of-the-art automatic speech recognition (ASR) engines perform well on healthy speech; however recent studies show that their performance on dysarthric speech is highly variable. This is because of the acoustic variability associated with the different dysarthria subtypes. This paper aims to develop a better understanding of how perceptual disturbances in dysarthric speech relate to ASR performance. Accurate ratings of a representative set of 32 dysarthric speakers along different perceptual dimensions are obtained and the performance of a representative ASR algorithm on the same set of speakers is analyzed. This work explores the relationship between these ratings and ASR performance and reveals that ASR performance can be predicted from perceptual disturbances in dysarthric speech with articulatory precision contributing the most to the prediction followed by prosody.