gebhart/patrepeval huggingface dataset:
An Isolated Semiresonant DC/DC Converter for High Power Applications (2016)

A zero-current switching full-bridge isolated dc/dc converter based on a semiresonant L-C cell has been developed in this paper. With respect to the classical full-bridge configuration, no additional switches are required, thus by preserving its simplicity and robustness. The proposed architecture allows achieving zero-current switching at both primary and secondary sides. A 50-kW prototype has been developed and tested in different operating conditions. The experimental results are in agreement with the simulations by confirming the goodness of the proposed solution. Efficiency up to 97% at full load operating condition has been reached in the laboratory prototype.
Mixed Mode Growth Model for the Solid Electrolyte Interface (SEI) (2019)

A mixed mode solid electrolyte interphase (SEI) growth model is presented that includes both the influence of the kinetics of the solvent reduction reaction at the SEI/electrode interface and diffusion of the solvent through the SEI layer. The governing equations are solved numerically to predict the solvent concentration profile, the SEI layer thickness, and the capacity loss. Capacity loss predictions are fitted to two sets of experimental data from the literature. The high quality of the fits demonstrates that the mixed mode model provides a useful description of the capacity loss in the cell due to the growth of the SEI layer on the anode under constant voltage storage condition. Also, analytical expressions are presented for SEI growth for both the combined kinetics/diffusion mode (mixed mode model) and the limit of a fast solvent reduction reaction (diffusion limited mode model) as a function of cell characteristics.
KIT Signaling Governs Differential Sensitivity of Mature and Primitive CML Progenitors to Tyrosine Kinase Inhibitors (2013)

Imatinib and other BCR-ABL1 inhibitors are effective therapies for chronic myelogenous leukemia (CML), but these inhibitors target additional kinases including KIT, raising the question of whether off-target effects contribute to clinical efficacy. On the basis of its involvement in CML pathogenesis, we hypothesized that KIT may govern responses of CML cells to imatinib. To test this, we assessed the growth of primary CML progenitor cells under conditions of sole BCR-ABL1, sole KIT, and dual BCR-ABL1/KIT inhibition. Sole BCR-ABL1 inhibition suppressed mature CML progenitor cells, but these effects were largely abolished by stem cell factor (SCF) and maximal suppression required dual BCR-ABL1/KIT inhibition. In contrast, KIT inhibition did not add to the effects of BCR-ABL1 inhibition in primitive progenitors, represented by CD34(+)38(-) cells. Long-term culture-initiating cell assays on murine stroma revealed profound depletion of primitive CML cells by sole BCR-ABL1 inhibition despite the presence of SCF, suggesting that primitive CML cells are unable to use SCF as a survival factor upon BCR-ABL1 inhibition. In CD34(+)38(+) cells, SCF strongly induced pAKT(S473) in a phosphoinositide 3-kinase (PI3K)-dependent manner, which was further enhanced by inhibition of BCR-ABL1 and associated with increased colony survival. In contrast, pAKT(S473) levels remained low in CD34(+)38(-) cells cultured under the same conditions. Consistent with reduced response to SCF, KIT surface expression was significantly lower on CD34(+)38(-) compared with CD34(+)38(+) CML cells, suggesting a possible mechanism for the differential effects of SCF on mature and primitive CML progenitor cells.
Combining conjunctive rule extraction with diffusion maps for network intrusion detection (2013)

Network security and intrusion detection are important in the modern world where communication happens via information networks. Traditional signature-based intrusion detection methods cannot find previously unknown attacks. On the other hand, algorithms used for anomaly detection often have black box qualities that are difficult to understand for people who are not algorithm experts. Rule extraction methods create interpretable rule sets that act as classifiers. They have mostly been combined with already labeled data sets. This paper aims to combine unsupervised anomaly detection with rule extraction techniques to create an online anomaly detection framework. Unsupervised anomaly detection uses diffusion maps and clustering for labeling an unknown data set. Rule sets are created using conjunctive rule extraction algorithm. This research suggests that the combination of machine learning methods and rule extraction is a feasible way to implement network intrusion detection that is meaningful to network administrators.
Wafer plane inspection evaluated for photomask production (2008)

Wafer Plane Inspection (WPI) is a novel approach to inspection, developed to enable high inspectability on fragmented mask features at the optimal defect sensitivity. It builds on well-established high resolution inspection capabilities to complement existing manufacturing methods. The production of defect-free photomasks is practical today only because of informed decisions on the impact of defects identified. The defect size, location and its measured printing impact can dictate that a mask is perfectly good for lithographic purposes. This inspection - verification - repair loop is timeconsuming and is predicated on the fact that detectable photomask defects do not always resolve or matter on wafer. This paper will introduce and evaluate an alternative approach that moves the mask inspection to the wafer plane. WPI uses a high NA inspection of the mask to construct a physical mask model. This mask model is used to create the mask image in the wafer plane. Finally, a threshold model is applied to enhance sensitivity to printing defects. WPI essentially eliminates the non-printing inspection stops and relaxes some of the pattern restrictions currently placed on incoming photomask designs. This paper outlines the WPI technology and explores its application to patterns and substrates representative of 32nm designs. The implications of deploying Wafer Plane Inspection will be discussed.
Differential regulation of viral and cellular genes in F9 mouse embyronal carcinoma cells (1987)

Expression of genes driven by the SV40 promoter/enhancer appears to be under net negative regulatory control in undifferentiated F9 cells, but not in their differentiated derivatives. In cells containing integrated copies of an SV40 promoter-driven marker gene, induction of differentiation by retinoic acid treatment produced a modest increase in transcription from the viral promoter. A much greater increase was observed when differentiated or undifferentiated cells were treated with the protein synthesis inhibitor, cycloheximide. If cycloheximide acts through removal of negative-regulatory molecule(s), then it is apparent that these molecules are present in both differentiated and undifferentiated cells, and that retinoic acid treatment removes only a portion of the total transcriptional repression. RNA levels from a variety of cellular genes activated during F9 cell differentiation were either unaffected or only slightly increased by cycloheximide treatment. This suggests important qualitative or quantitative differences in the regulation mechanism for viral and cellular genes in differentiating F9 cells.
An experiment in table driven code generation (1982)

We have constructed a local code generator for the VAX-11 2 using a parser-like instruction pattern matcher. The code generator replaces the second pass of the UNIX 3 Portable “Crdquo; compiler. This paper describes the design of the code generator and the special considerations imposed by the pattern matching process. We summarize the structure of the machine description grammar and its associated semantic actions, as well as the tools we developed to manipulate the large VAX description. In our experience, this approach makes the instruction selection phase of the compiler easier and faster to implement, and more likely to be correct than traditional techniques.
Fluid dynamics of smoke from enclosure fires (2020)

Esta tesis revisa los modelos actualmente disponibles para representar el humo producido por incendios en recintos cerrados, desde las correlaciones más básicas de entrada de aire en el penacho hasta los modelos más avanzados de Mecánica de Fluido Computacional (CFD). Con el fin de revisar estos modelos, se realizaron varios experimentos a escala real, con diferentes tamaños de incendio, combustibles, dimensiones y condiciones ambientales, en dos instalaciones diferentes: el Murcia Fire Atrium en Murcia, España, y la ITB Chamber en Varsovia, Polonia. Los datos obtenidos por estos experimentos se utilizaron para comprender y profundizar diferentes aspectos de los métodos actuales de modelización numérica del humo. Esta tesis ha puesto de relieve la importancia de definir correctamente las propiedades al modelar numéricamente el incendio, ya que pequeñas diferencias en los datos de entrada pueden generar un impacto importante en los resultados.
Sensing Thumb-to-Finger Taps for Symbolic Input in VR/AR Environments (2015)

Thumb-to-finger tap interaction can be employed to perform eyes-free, discrete, symbolic input in virtual and augmented reality environments. The DigiTap device is worn on the wrist to keep the hand free from any instrumentation so as not to impair tactile sense and dexterity. DigiTap senses the jerk that is caused by a tap and takes an image sequence to detect the tap location. The device can recognize taps at 12 different locations on the fingers, and at some positions, it can even distinguish between different tap strengths. The authors conducted an extended user study to evaluate users' abilities to interact with the device and perform symbolic input.
Fluorescent Sensors for Zn<sup>2+</sup>Based on a Fluorescein Platform:  Synthesis, Properties and Intracellular Distribution (2001)

Two new fluorescent sensors for Zn(2+) that utilize fluorescein as a reporting group, Zinpyr-1 and Zinpyr-2, have been synthesized and characterized. Zinpyr-1 is prepared in one step via a Mannich reaction, and Zinpyr-2 is obtained in a multistep synthesis that utilizes 4',5'-fluorescein dicarboxaldehyde as a key intermediate. Both Zinpyr sensors have excitation and emission wavelengths in the visible range ( approximately 500 nm), dissociation constants (K(d1)) for Zn(2+) of <1 nM, quantum yields approaching unity (Phi = approximately 0.9), and cell permeability, making them well-suited for intracellular applications. A 3- to 5-fold fluorescent enhancement is observed under simulated physiological conditions corresponding to the binding of the Zn(2+) cation to the sensor, which inhibits a photoinduced electron transfer (PET) quenching pathway. The X-ray crystal structure of a 2:1 Zn(2+):Zinpyr-1 complex has also been solved, and is the first structurally characterized example of a complex of fluorescein substituted with metal binding ligands.
Home Studio: A Mixed Reality Staging Tool for Interior Design (2021)

Home design services employ virtual real estate staging to visually convey proposals to prospective customers, instilling confidence in property owners on how spaces will look once they are furnished. However, creating room-scale visualizations requires days of expert labor to composite products on images provided by the customer. Advances in 3D capture now let users scan their spaces with a smartphone in a matter of minutes, enabling scale-accurate mixed reality experiences that can be leveraged to lower the skill bar and time required to produce visualizations of furniture in the user’s context. We present Home Studio, a web-based tool that lets designers stage any Matterport scan and generate photorealistic renders of products in the user’s context. Our tool enables a drag and drop experience that reconstructs the perspective view of the Matterport scene in a remote service, employing a rendering engine to produce a photorealistic composite.
Molecular Classification Identifies a Subset of Human Papillomavirus–Associated Oropharyngeal Cancers With Favorable Prognosis (2006)

Using this system for classification, we define the molecular profile of HPV+ OSCC with favorable prognosis, namely HPV+/p16 high (class III). This study defines a novel classification scheme that may have value for patient stratification for clinical trials testing HPV-targeted therapies.
Polarization change in ferroelectric thin film capacitors under external stress (2009)

The changes in polarization and coercive voltage of lead zirconate titanate (PZT) thin film of 130 nm in thickness were measured under hydrostatic pressure up to 1.5 GPa. By converting the isotropic loading to an equivalent out-of-plane uniaxial compressive loading, it was found that these results were consistent with our previous results of uniform in-plane tensile stress, showing that the polarization changes under these two different loading conditions are of the same nature. The combined results demonstrate that the intrinsic polarization decreased linearly with the level of stress at a rate of −0.013 μC cm−2 MPa−1 with a critical stress of 1.6 GPa to paraelectric phase. Further comparison of our result with that of a thick PZT film and bulk PZT materials suggests that ferroelastic switching (90° switching) is dominant in the bulk material, and the polarization reduction in our thin film is due to material intrinsic lattice distortion under pressure, while the thick film response is intermediate. The effect of substrate clamping on ferroelastic domains is also shown.
Monitoring for the Process Conditions of Chitosan Using Response Surface Methodology (1999)

Response surface methodology was used for monitoring physicochemical properties of chitosan with preparation of chitosan. Deacetylation degree of chitosan was in proportion to NaOH concentration for deacetylation of chitosan. The solubility of chitosan was maximized in 52% (concentration of NaOH), (deacetylation temperature) and 123 min (deacetylation time). Viscosity of chitosan was mainly influenced by concentration of NaOH, and was greatly decreased with the increase of concentration of NaOH. The optimum condition ranges for preparation of chitosan was NaOH, in deacetylation temperature and in deacetylation time.
Algebraic MACs and Keyed-Verification Anonymous Credentials (2014)

We consider the problem of constructing anonymous credentials for use in a setting where the issuer of credentials is also the verifier, or more generally where the issuer and verifier have a shared key. In this setting we can use message authentication codes (MACs) instead of public key signatures as the basis for the credential system.
Synthesis and study of new .alpha.-haloacid ferroelectric liquid crystal derivatives. MM2 approach to the molecular structure-ferroelectric activity relationship (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis and study of new .alpha.-haloacid ferroelectric liquid crystal derivatives. MM2 approach to the molecular structure-ferroelectric activity relationshipT. Sierra, J. L. Serrano, M. B. Ros, A. Ezcurra, and J. ZubiaCite this: J. Am. Chem. Soc. 1992, 114, 20, 7645–7651Publication Date (Print):September 1, 1992Publication History Published online1 May 2002Published inissue 1 September 1992https://pubs.acs.org/doi/10.1021/ja00046a007https://doi.org/10.1021/ja00046a007research-articleACS PublicationsRequest reuse permissionsArticle Views340Altmetric-Citations41LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A high coherence supercontinuum source at 1550 nm (2003)

We present a low noise supercontinuum source based on a femtosecond fiber laser. Varying the dispersion along the fiber length generates a flat, symmetrically broadened continuum. No degradation in coherence is observed.
Human Performance on the Traveling Salesman and Related Problems: A Review (2011)

The article provides a review of recent research on human performance on the traveling salesman problem (TSP) and related combinatorial optimization problems. We discuss what combinatorial optimization problems are, why they are important, and why they may be of interest to cognitive scientists. We next describe the main characteristics of human performance on the TSP and related problems, and discuss the main theoretical explanations that have been offered. We then review some related developments in animal studies, spatial cognition, and neuropsychology. The article closes with a brief look at possible future directions.
SiC: A Photocathode for Water Splitting and Hydrogen Storage (2009)

Ein p-Halbleiter bestehend aus 4H-SiC ist bei Lichteinstrahlung zur Wasserspaltung befähigt, wenn er als Photokathode mit einer Pt-Anode kurzgeschlossen wird. Der erzeugte Wasserstoff wird zu einem beträchtlichen Teil im Festkörper gespeichert.
Micromachined Transmission Lines for Millimeter-Wave Applications (2006)

Several different fabrication techniques and materials have been proposed for making low loss high performance micromachined transmission lines. In this paper a review of several micromachined transmission lines that have been proposed over the last years are classified into four types according to their physical structure and their power losses addressed.
Sickle Erythrocytes Target Cytotoxics to Hypoxic Tumor Microvessels and Potentiate a Tumoricidal Response (2013)

Resistance of hypoxic solid tumor niches to chemotherapy and radiotherapy remains a major scientific challenge that calls for conceptually new approaches. Here we exploit a hitherto unrecognized ability of sickled erythrocytes (SSRBCs) but not normal RBCs (NLRBCs) to selectively target hypoxic tumor vascular microenviroment and induce diffuse vaso-occlusion. Within minutes after injection SSRBCs, but not NLRBCs, home and adhere to hypoxic 4T1 tumor vasculature with hemoglobin saturation levels at or below 10% that are distributed over 70% of the tumor space. The bound SSRBCs thereupon form microaggregates that obstruct/occlude up to 88% of tumor microvessels. Importantly, SSRBCs, but not normal RBCs, combined with exogenous prooxidant zinc protoporphyrin (ZnPP) induce a potent tumoricidal response via a mutual potentiating mechanism. In a clonogenic tumor cell survival assay, SSRBC surrogate hemin, along with H(2)O(2) and ZnPP demonstrate a similar mutual potentiation and tumoricidal effect. In contrast to existing treatments directed only to the hypoxic tumor cell, the present approach targets the hypoxic tumor vascular environment and induces injury to both tumor microvessels and tumor cells using intrinsic SSRBC-derived oxidants and locally generated ROS. Thus, the SSRBC appears to be a potent new tool for treatment of hypoxic solid tumors, which are notable for their resistance to existing cancer treatments.
Safety and tolerability of iobitridol in cerebral angiography: a prospective, multicenter study (2019)

Background To date, only a few data have demonstrated the safety of iodinated contrast media for cerebral angiography. Purpose To assess contrast-related adverse events after cerebral angiography using iobitridol. Material and Methods A total of 790 patients who underwent cerebral angiography at three tertiary hospitals in the Republic of Korea between November 2017 and October 2018 were prospectively enrolled in this study. We interviewed all patients and recorded their symptoms before they left the interventional clinic after the angiography procedure and during the seven-day follow-up visit. The primary endpoints were acute (within 1 h) and delayed (1 h–7 days) adverse events associated with iobitridol injection. We also visually graded the radiographic density and image quality as secondary endpoints. Results Acute adverse events were more common than delayed adverse events. Most adverse events were either mild (96.5%) or moderate (3.45%). Among the contrast-related adverse events, feeling of warmth (59.1%) and altered taste (17.5%) were the most common acute events, whereas headache (41.9%) and allergic skin reactions (20.0%) were the most common delayed events. All cerebral angiography showed optimal density and good/excellent image quality. Conclusion The findings of this study suggest that iobitridol is a safe and effective iodinated contrast medium for use in cerebral angiography.
Generating the sparse point cloud of a civil infrastructure scene using a single video camera under practical constraints (2011)

Automating the model generation process of infrastructure can substantially reduce the modeling time and cost. This paper presents a method to generate a sparse point cloud of an infrastructure scene using a single video camera under practical constraints. It is the first step towards establishing an automatic framework for object-oriented as-built modeling. Motion blur and key frame selection criteria are considered. Structure from motion and bundle adjustment are explored. The method is demonstrated in a case study where the scene of a reinforced concrete bridge is videotaped, reconstructed, and metrically validated. The result indicates the applicability, efficiency, and accuracy of the proposed method.
Compressor Stall Control Through Endwall Recirculation (2004)

Experiments that demonstrate the use of endwall recirculation to control the stall of transonic compressor stages are described. Endwall recirculation of a compressor stage is implemented by bleeding air from the casing downstream of a stator blade row and injecting the air as a wall jet upstream of a preceding rotor blade row. The bleed ports, injection ports, and recirculation channels are circumferentially discrete, and occupy only 20–30% of the circumference. The development of compact wall-jet injectors is described first. Next, the results of proof-of-concept steady recirculation tests on a single-stage transonic compressor are presented. Finally, the potential for using endwall recirculation to increase the stability of transonic highly-loaded multistage compressors is demonstrated through results from a rig test of simulated recirculation driving both a steady injected flow and an unsteady injected flow commanded by closed-loop active control during compressor operation at 78–100% of design speed. In this test air from an external source was injected upstream of several rotor blade rows while compressor bleed was increased by an amount equivalent to the injected massflow. During closed loop control, wall static pressure fluctuations were monitored and the injected flow rate was controlled to reduce the stalling mass flow. The use of wall jet injection to study the dynamics of transonic compressor stages is also discussed.