gebhart/patrepeval huggingface dataset:
Cloning and Expression of the Anti tumor Glycoprotein Gene of<i>Streptococcus pyogenes</i>Su in<i>Escherichia coli</i> (1987)

The structural gene for the streptococcal acid glycoprotein (SAGP), an antitumor glycoprotein produced by Streptococcus pyogenes Su, was cloned in Escherichia coli, and the nucleotide sequence was determined. The deduced amino acid sequence of SAGP was composed of 410 amino acids, and was highly homologous with colicin E1, a bacterial antimicrobial protein. The SAGP gene was subcloned into an expression plasmid and was expressed in E. coli. The gene product was demonstrated to have almost the same molecular weight and an immuno-chemical property with those of the native SAGP.
Machine performance monitoring and fault classification using an exponentially weighted moving average scheme (1995)

Performance monitoring is crucial in maintaining normal machine operating conditions for the continued production of high quality parts. The objective of the following research is to develop an effective performance monitoring technique to assess the condition of rotating machinery through vibration signature analysis. An autoregressive (AR) model is utilized to characterize normal vibration signals, the modified covariance method calculates the deviation of the current condition from a normal condition, and an exponentially weighted moving average (EWMA) statistic measures the current machine condition by signalling either a normal or an out-of-control condition, The following paper discusses the statistical techniques employed in performance monitoring. Preliminary studies show that these techniques provide accurate performance monitoring of the operating condition of rotating machinery using vibration signals.
Novel, Rapid Identification, and Quantification of Adulterants in Extra Virgin Olive Oil Using Near‐Infrared Spectroscopy and Chemometrics (2015)

A new, rapid Fourier transform near infrared (FT-NIR) spectroscopic procedure is described to screen for the authenticity of extra virgin olive oils (EVOO) and to determine the kind and amount of an adulterant in EVOO. To screen EVOO, a partial least squares (PLS1) calibration model was developed to estimate a newly created FT-NIR index based mainly on the relative intensities of two unique carbonyl overtone absorptions in the FT-NIR spectra of EVOO and other mixtures attributed to volatile (5280 cm(-1)) and non-volatile (5180 cm(-1)) components. Spectra were also used to predict the fatty acid (FA) composition of EVOO or samples spiked with an adulterant using previously developed PLS1 calibration models. Some adulterated mixtures could be identified provided the FA profile was sufficiently different from those of EVOO. To identify the type and determine the quantity of an adulterant, gravimetric mixtures were prepared by spiking EVOO with different concentrations of each adulterant. Based on FT-NIR spectra, four PLS1 calibration models were developed for four specific groups of adulterants, each with a characteristic FA composition. Using these different PLS1 calibration models for prediction, plots of predicted vs. gravimetric concentrations of an adulterant in EVOO yielded linear regression functions with four unique sets of slopes, one for each group of adulterants. Four corresponding slope rules were defined that allowed for the determination of the nature and concentration of an adulterant in EVOO products by applying these four calibration models. The standard addition technique was used for confirmation.
Super-Gaussian output from a cw-CO2 laser by using a graded phase mirror resonator (1992)

We have mirror for a resonator having a specified output. 1,2 We have shown that certain optical resonators can have a fundamental mode of a stable type with a large beam waist and, at the same time, higher-order modes with large losses. The design of highly discriminating laser resonators is thus possible. We now present some experimental results for such a custom output laser device. The performances of two resonators have been compared. The graded-phase feedback mirrors are differently designed in order to provide two different super-Gaussian output beams with the following amplitude profiles: exp[−( r /2.5) 2 ] and exp[−( r /3.2) 6 ], where r is the transverse circular coordinate measured in millimeters. The first mirror is of course spherical, and the resonator is semiconfocal. The gain medium is a cw-CO 2 circular discharge section of 18 mm of diameter. The maximum monomode power output for the conventional spherical resonator is 5 W. With the graded-phase mirror, increases of monomode power output of 25% have been measured. These observations are in close agreement with theoretical calculations of the efficiency of these resonators, taking into account the saturation. Beam profiles in the near field and far field have been measured and are presented.
Tunable two-mirror interference lithography system for wafer-scale nanopatterning (2011)

We have designed and analyzed a novel (to the best of our knowledge) two-beam interference lithography system for large-area (wafer-level) nanopatterning with enhanced tunability of pattern periodicities. The tunable feature has been achieved by placing two rotational mirrors in the expanded beam paths at regulated angles for a desired period. Theoretical analyses show that the effective pattern coverage area greater than a 4 in. (10 cm) wafer scale is attainable with a 325 nm (30 cm coherence length) HeCd laser and 4 in. (10 cm) mirrors, while the pattern coverage area is restrained by the overruling effects between the optical coherence and mirror size. The experimental results also demonstrate uniform nanopatterns at varying periods (250-750 nm) on 4 in. (10 cm) substrates, validating the theoretical analyses. The tunable two-mirror interferometer will offer a convenient and robust way to prepare large-area nanostructures on a wafer scale with superior tunability in their pattern periodicities.
The effect of rat acute-liver-failure plasma on HepaRG cells (2012)

HepaRG cells are negatively affected by rat plasma, even of healthy origin. However, their ammonia eliminating capacity is relatively resistant, underlining their suitability for BAL application. DMSO pre-treatment may increase their viability in plasma.
Filter Banks For Hearing Aids Applying Subband Amplification: A Comparison Of Different Specification And Design Approaches (2009)

Publication in the conference proceedings of EUSIPCO, Glasgow, Scotland, 2009
The Kramers–Kronig Receiver (2018)

This presentation reviews the operation principles and various implementations of the Kramers-Kronig (KK) receiver. We show that the KK scheme offers new ways of considering the process of data transmission and reception, with respect to the use of the spectral and polarization degrees of freedom. Some of the recently published experimental demonstrations are reviewed.
Numerical Modeling of Active Flow Control in a Boundary Layer Ingesting Offset Inlet (2004)

This investigation evaluates the numerical prediction of flow distortion and pressure recovery for a boundary layer ingesting offset inlet with active flow control devices. The numerical simulations are computed using a Reynolds averaged Navier-Stokes code developed at NASA. The numerical results are validated by comparison to experimental wind tunnel tests conducted at NASA Langley Research Center at both low and high Mach numbers. Baseline comparisons showed good agreement between numerical and experimental results. Numerical simulations for the inlet with passive and active flow control also showed good agreement at low Mach numbers where experimental data has already been acquired. Numerical simulations of the inlet at high Mach numbers with flow control jets showed an improvement of the flow distortion. Studies on the location of the jet actuators, for the high Mach number case, were conducted to provide guidance for the design of a future experimental wind tunnel test.
Semantically-Guided Representation Learning for Self-Supervised Monocular Depth (2020)

Self-supervised learning is showing great promise for monocular depth estimation, using geometry as the only source of supervision. Depth networks are indeed capable of learning representations that relate visual appearance to 3D properties by implicitly leveraging category-level patterns. In this work we investigate how to leverage more directly this semantic structure to guide geometric representation learning, while remaining in the self-supervised regime. Instead of using semantic labels and proxy losses in a multi-task approach, we propose a new architecture leveraging fixed pretrained semantic segmentation networks to guide self-supervised representation learning via pixel-adaptive convolutions. Furthermore, we propose a two-stage training process to overcome a common semantic bias on dynamic objects via resampling. Our method improves upon the state of the art for self-supervised monocular depth prediction over all pixels, fine-grained details, and per semantic categories.
Demonstration of Haptic Revolver (2018)

We present Haptic Revolver, a handheld virtual reality controller that renders fingertip haptics when interacting with virtual surfaces. Haptic Revolver's core haptic element is an actuated wheel that raises and lowers underneath the finger to render contact with a virtual surface. As the user's finger moves along the surface of an object, the controller spins the wheel to render shear forces and motion under the fingertip. The wheel is interchangeable and can contain physical textures, shapes, edges, or active elements to provide different sensations to the user. Because the controller is spatially tracked, these physical features can be spatially registered with the geometry of the virtual environment and rendered on-demand.
Reversal ion source: A new source of negative ion beams (1985)

We demonstrate a new type of ion source for producing either pulsed or continuous negative ion beams. The source, dubbed the ‘‘reversal ion source,’’ utilizes an electrostatic ‘‘mirror’’ which reverses trajectories in an electron beam, producing electrons at their turning point having a distribution of velocities centered at zero velocity. A gas which attaches zero-velocity electrons is introduced at this turning point. Negative ions are produced by the attachment or dissociative attachment process. The cross section for this process is extremely large, varying as (electron energy)−1/2, or just the s-wave threshold law. The operation of the source is demonstrated for continuous and pulsed production of Cl− beams by dissociative attachment to CFCl3. Estimates of the current density of this source are given, and applications to the production of ions through higher energy resonances are discussed.
4-Quinolone Derivatives:  High-Affinity Ligands at the Benzodiazepine Site of Brain GABA<sub>A</sub>Receptors. Synthesis, Pharmacology, and Pharmacophore Modeling (2006)

The 3-ethoxycarbonyl-4-quinolone compound 1 has previously been identified via a database search as an interesting lead compound for ligand binding at the benzodiazepine site of GABA(A) receptors (Kahnberg et al. J. Mol. Graphics Modelling 2004, 23, 253-261). Pharmacophore-guided optimization of this lead compound yielded a number of high-affinity ligands for the benzodiazepine site including compounds 20 and 23-25 displaying sub-nanomolar affinities. A few of the compounds have been tested on the alpha(1)beta(2)gamma(2S) and alpha(3)beta(2)gamma(2S) GABA(A) receptor subtypes, and two of the compounds (5 and 19) display selectivity for alpha(1)- versus alpha(3)-containing receptors by a factor of 22 and 27, respectively. This selectivity for alpha(1)beta(2)gamma(2S) is in the same range as that for the well-known alpha(1) subunit selective compound zolpidem.
A Multidimensional Approach to Context-Awareness (2003)

This paper presents multidimensional context-aware principles for Enterprise Applications. The usage of information about the environment of an application, device or its user can enhance the functionality of applications. Information about the user as a subset of contextual information enables applications to cultivate a relationship with their human users, which allows individual support of individual users. This paper introduces a view to different dimensions of context. As contextual dimensions we define different aspects of the environment, which are independent of each other. Examples for contextual dimensions are the personality of the user, her location and the devices she carries. Another contextual dimension, which this paper presents in detail, is the way in which contextual information is determined. Hard context-awareness is the measuring of contextual information using hardware sensors, while soft context-awareness is the inference of knowledge based on a context-aware reuse of the information base. We present ways to combine data of different applications and infer contextual information out of this data. We view context-awareness from the perspective of Enterprise Applications and their special requirements. We present special characteristics of Enterprise Applications and how they influence the use of contextual information in enterprises.
PseudoMorphic Glass to enable high efficiency space photovoltaic devices (2011)

Solar cell manufacturers have indicated that new, high efficiency solar cells will require coverglass with higher UV transmittance than currently existing materials. To date, fused silica is the only known solution but has several significant technical and cost challenges. In addition, new solar cells demonstrating record efficiency and extreme flexibility have been developed. Integrating these advanced devices with traditional coverglasses limits the ability to take advantage of novel packaging options, such as rolled blankets. A new coverglass replacement technology has been developed, termed PseudoMorphic Glass (PMG), which has the potential to meet these needs. PMG has the potential to provide the high UV spectral transmissivity required for next generation solar cells in a robust, flexible and fully encapsulating format.
Portable device for presbyopia correction with optoelectronic lenses driven by pupil response (2020)

A novel portable device has been developed and built to dynamically, and automatically, correct presbyopia by means of a couple of opto-electronics lenses driven by pupil tracking. The system is completely portable providing with a high range of defocus correction up to 10 D. The glasses are controlled and powered by a smartphone. To achieve a truly real-time response, image processing algorithms have been implemented in OpenCL and ran on the GPU of the smartphone. To validate the system, different visual experiments were carried out in presbyopic subjects. Visual acuity was maintained nearly constant for a range of distances from 5 m to 20 cm.
Optimizing throughput in optical networks: The joint routing and power control problem (2015)

It is well established that physical layer impairments significantly affect the performance of optical networks. The management of these impairments is critical for successful transmission, and may significantly affect network layer routing decisions. Hence the traditional divide-and-conquer layered approach is sub-optimal, which has led to work on cross-layer techniques for routing in optical networks. Apart from fiber loss, one critical physical layer impairment that limits the capacity of optical networks is fiber nonlinearity. Handling nonlinearity introduces significant complexity to the traditional cross-layer approaches. We formulate and solve a joint routing and power control problem to optimize the system throughput that takes into consideration both fiber loss and nonlinearity. The joint power control and routing problem considered is a nonlinear integer programming problem. By characterizing the feasible solution space of the power control problem we find a set of universal power settings that transforms the complex power control and routing problem into a constrained path routing problem. We then propose an efficient Fully Polynomial Time Approximation Scheme (FPTAS) to solve the constrained path routing problem. Simulation results show that our proposed algorithm significantly improves network throughput and greatly outperforms greedy heuristics by providing a guaranteed performance bound.
Magnetic properties and microstructure of FePt–Si3N4 nanocomposite thin films (2000)

( Fe 50 Pt 50 ) 100−x –( Si 3 N 4 ) x (x=0–50 vol. %) nanocomposite thin films are prepared by dc and rf magnetron cosputtering of FePt and Si3N4 targets on silicon wafer substrates, then annealed in vacuum at various temperatures. The effects of Si3N4 volume fraction, film thickness, and annealing temperatures on the magnetic properties are investigated. Transmission electron microscopy analysis indicated that structurally the film is an amorphous Si3N4 matrix with spherical FePt particles dispersed in it. The particle size of FePt increases with the annealing temperature but decreases with increasing Si3N4 content. Magnetization measurements indicated that maximum in-plane squareness and coercivity occurs at 30 vol. % of Si3N4 after annealing the film at 750 °C for 30 min. The average particle size of FePt in this film is about 40 nm. Saturation magnetization of the FePt–Si3N4 film is independent of film thickness but inversely proportional to the Si3N4 volume fraction. Variation of the films’ coercivity with film thickness is small. In contrast, the magnetic hardening mechanism and coercivity of the FePt–Si3N4 composite film are dependent on the Si3N4 volume fraction.
Planar flexible fiber-optic acoustic sensors (1990)

The acoustic sensitivity of optical fibers is considered analytically. High sensitivity is obtained with low bulk modulus, very thick polymeric coatings. The fiber coatings play an important role in determining the fiber acoustic sensitivity. The very thick coating limit is realized by embedding optical fibers in an appropriate elastomer (polyurethane). A planar flexible fiber-optic interferometric acoustic sensor is developed by wrapping optimized single-mode fibers in a planar spiral form, and then embedding the fiber in a thin polyurethane layer. The acoustic sensitivity of the sensor is found to be high, and frequency (0.2-2.5 kHz) and static pressure independent. The sensor is found to be compatible with water, and is compared favorably to that of a planar polyvinylidene fluoride sensor of similar geometry.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A novel mutation in TTC8 is associated with progressive retinal atrophy in the golden retriever (2014)

Our results show that PRA is genetically heterogeneous in one of the world's numerically largest breeds, the Golden Retriever, and is caused by multiple, distinct mutations. Here we discuss the mutation that causes a form of PRA, that we have termed PRA2, that accounts for approximately 30% of PRA cases in the breed. The genetic explanation for approximately 9% of cases remains to be identified. PRA2 is a naturally occurring animal model for Retinitis Pigmentosa, and potentially Bardet-Biedl Syndrome.
A novel matrix‐assisted laser desorption/ionisation mass spectrometry imaging based methodology for the identification of sexual assault suspects (2011)

An increase in the use of condoms by sexual offenders has been observed. This is likely to be due both to the risk of sexually transmitted diseases and to prevent the transfer of DNA evidence. In this scenario the detection of condom lubricants at a crime scene could aid in proving corpus delicti. Here we show a novel application of Matrix-Assisted Laser Desorption/Ionisation Mass Spectrometry Imaging (MALDI MSI) for mapping the fingermark ridge pattern simultaneously to the detection of the condom lubricant within the fingermark itself. Two condom brands have been investigated to prove the concept. Condoms were handled producing lubricant-contaminated fingermarks. Images of the ridge pattern were obtained simultaneously to the detection of two lubricants, even several weeks after the fingermark deposition. The results therefore show the potential of MALDI MSI to link the suspect (identification through fingermark ridge pattern) to the crime (detection of condom lubricant) in one analysis. This would enable forensic scientists to provide evidence with stronger support in alleged cases of sexual assault.
A laser interferometer for measuring skin friction in three-dimensional flows (1983)

A new, nonintrusive method is described for measuring skin friction in three-dimensional flows with unknown direction. The method uses a laser interferometer to measure the changing slope of a thin oil film applied to a surface experiencing shear stress. The details of the method are described, and skin friction measurements taken in a swirling three-dimensional boundary-layer flow are presented. Comparisons between analytical results and experimental values from the laser interferometer method and from a bidirectional surface-fence gauge are made.
Nonchamber, Root-Side, Inert-Gas Purging During Welding (1995)

Improved apparatus distributes inert gas to protect against oxidation on root side of weld during welding and after welding while joint remains hot. Simple and lightweight; readily moved along weld path in synchronism with torch. Because it concentrates inert gas where needed, consumes gas at relatively low rate, and not necessary to monitor oxygen content of protective atmosphere. Apparatus does not obscure view of root side of weld. Used for full-penetration plasma-arc welding of such reactive metals as aluminum/lithium alloys and titanium.
A low power configurable bio-impedance spectroscopy (BIS) ASIC with simultaneous ECG and respiration recording functionality (2015)

This paper presents a power-efficient ASIC for bio-impedance spectroscopy, as well as ECG and respiration recording. The ASIC includes a wideband stimulation current source with a pseudo-random binary sequence, a low-noise instrumentation amplifier, and a low power 12b SAR ADC. This ASIC is able to measure bio-impedances from 1Ω to 10kΩ with 0.1Ω resolution, and covers a frequency range up to 125kHz. Furthermore, the ASIC can simultaneously record ECG and respiration while consuming only 31μW from a 1.8V supply.
Terahertz Quantum Cascade Laser Source Based on Intra-Cavity Difference-Frequency Generation (2007)

This paper aims to integrate AlInAs/InGaAs quantum well structures with high second-order nonlinear susceptibility into a dual-wavelength quantum cascade laser (QCL) for difference frequency generation (DFG) of THz radiation. The QCL active region contains two sections: a section with 30 cascades of bound-to-continuum design with integrated optical nonlinearity emitting at 8.7 mum and a section with 20 cascades of two-phonon design emitting at 7.6 mum. The nonlinear susceptibility for the DFG process is found to have a value of chi <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">(2)</sup> ~4times10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">5</sup> pm/V.