gebhart/patrepeval huggingface dataset:
Fast Equi-Join Algorithms on GPUs (2017)

Processing relational joins on modern GPUs has attracted much attention in the past few years. With the rapid development on the hardware and software environment in the GPU world, the existing GPU join algorithms designed for earlier architecture cannot make the most out of latest GPU products. In this paper, we report new design and implementation of join algorithms with high performance under today's GPGPU environment. This is a key component of our scientific database engine named G-SDMS. In particular, we overhaul the popular radix hash join and redesign sort-merge join algorithms on GPUs by applying a series of novel techniques to utilize the hardware capacity of latest Nvidia GPU architecture and new features of the CUDA programming framework. Our algorithms take advantage of revised hardware arrangement, larger register file and shared memory, native atomic operation, dynamic parallelism, and CUDA Streams. Experiments show that our new hash join algorithm is 2.0 to 14.6 times as efficient as existing GPU implementation, while the new sort-merge join achieves a speedup of 4.0X to 4.9X. Compared to the best CPU sort-merge join and hash join known to date, our optimized code achieves up to 10.5X and 5.5X speedup. Moreover, we extend our design to scenarios where large data tables cannot fit in the GPU memory.
High-birefringence hollow-core anti-resonant fiber (2020)

We report the first high-birefringence hollow-core anti-resonant fiber with a pseudoCv symmetry. The resulted fiber shows a phase birefringence, polarization etfinction ratio, and loss of 0.9 X10 -4 , 25 dB, and 250 dB/km, respectively, at 1550 nm.
Three mouse monoclonal antibodies to human differentiation antigens: reactivity with two mucin-like antigens and with connective tissue fibers. (1985)

Three human differentiation antigens (MU78, MT334, and MQ49) have been defined by mouse monoclonal antibodies developed from mice immunized with ovarian carcinoma cell lines. Their distribution was determined on 148 cultured cell lines of various histologic types and on frozen sections of 16 normal tissues. MU78 was found in fibrillar structures in soft connective tissue with a distribution resembling that of elastin fibers; however, elastin fibers in elastic cartilage and in the aorta were nonreactive. MU78 was detected in cultured carcinoma cells of various histologic types, where it had a nonfibrillar, cytoplasmic distribution, but was not detected in normal epithelial cells in frozen sections. Cultured fibroblasts, astrocytomas, melanomas, and lymphomas did not contain MU78. In cell lines, MU78 appears to be a protein of 2000-5000 daltons. The other two antigens, MT334 and MQ49, are both mucin-like molecules, and the determinants are probably carbohydrate in nature. Of the normal tissues examined, MT334 was detected only in goblet cells of the colon, though it was present in a variety of carcinomas in culture. It was detected as both a cytoplasmic and secreted component. MQ49 was detected in various secretory epithelial cells, in Hassall's corpuscles in the thymus, and in cultured carcinomas of various histologic types. It was found on the cell surface as well as in the cytoplasm and is present on a glycolipid as well as on a sulfated mucin. These results, and results of other recent studies, demonstrate the importance of mucin-like molecules as antigens in epithelial cells and secretions.
Rapid and enhanced activation of microporous coordination polymers by flowing supercritical CO2 (2013)

Flowing supercritical CO(2) was used to activate a cross section of microporous coordination polymers (MCPs) directly from DMF, thus avoiding exchange with a volatile solvent. Most MCPs displayed exceptional surface areas directly after treatment although those with coordinatively unsaturated metals benefit from heating. The method presents an advance in efficiency of activation and quality of material obtained.
Radiotherapeutic Bandage Based on Electrospun Polyacrylonitrile Containing Holmium-166 Iron Garnet Nanoparticles for the Treatment of Skin Cancer (2014)

Radiation therapy is used as a primary treatment for inoperable tumors and in patients that cannot or will not undergo surgery. Radioactive holmium-166 ((166)Ho) is a viable candidate for use against skin cancer. Nonradioactive holmium-165 ((165)Ho) iron garnet nanoparticles have been incorporated into a bandage, which, after neutron-activation to (166)Ho, can be applied to a tumor lesion. The (165)Ho iron garnet nanoparticles ((165)HoIG) were synthesized and introduced into polyacrylonitrile (PAN) polymer solutions. The polymer solutions were then electrospun to produce flexible nonwoven bandages, which are stable to neutron-activation. The fiber mats were characterized using scanning electron microscopy, transmission electron microscopy, powder X-ray diffraction, Fourier transform infrared spectroscopy, thermogravimetric analysis and inductively coupled plasma mass spectrometry. The bandages are stable after neutron-activation at a thermal neutron-flux of approximately 3.5 × 10(12) neutrons/cm(2)·s for at least 4 h and 100 °C. Different amounts of radioactivity can be produced by changing the amount of the (165)HoIG nanoparticles inside the bandage and the duration of neutron-activation, which is important for different stages of skin cancer. Furthermore, the radioactive bandage can be easily manipulated to irradiate only the tumor site by cutting the bandage into specific shapes and sizes that cover the tumor prior to neutron-activation. Thus, exposure of healthy cells to high energy β-particles can be avoided. Moreover, there is no leakage of radioactive material after neutron activation, which is critical for safe handling by healthcare professionals treating skin cancer patients.
Betidamino acids: versatile and constrained scaffolds for drug discovery. (1996)

Betidamino acids (a contraction of "beta" position and "amide") are N'-monoacylated (optionally, N'-monoacylated and N-mono- or N,N'-dialkylated) aminoglycine derivatives in which each N'acyl/alkyl group may mimic naturally occurring amino acid side chains or introduce novel functionalities. Betidamino acids are most conveniently generated on solid supports used for the synthesis of peptides by selective acylation of one of the two amino functions of orthogonally protected aminoglycine(s) to generate the side chain either prior to or after the elongation of the main chain. We have used unresolved Nalpha-tert-butyloxycarbonyl-N'alpha-fluorenylmethoxycarbonyl++ + aminoglycine, and Nalpha-(Nalpha-methyl)-tert-butyloxycarbonyl-N'alpha-fluo renylmethoxycarbonyl aminoglycine as the templates for the introduction of betidamino acids in Acyline [Ac-D2Nal-D4Cpa-D3Pal-Ser-4Aph(Ac)-D4Aph(A c)-Leu-Ilys-Pro-DAla-NH2, where 2Nal is 2-naphthylalanine, 4Cpa is 4-chlorophenylalanine, 3Pal is 3-pyridylalanine, Aph is 4-aminophenylalanine, and Ilys is Nepsilon-isopropyllysine], a potent gonadotropin-releasing hormone antagonist, in order to test biocompatibility of these derivatives. Diasteremneric peptides could be separated in most cases by reverse-phase HPLC. Biological results indicated small differences in relative potencies (<5-fold) between the D and L nonalkylated betidamino acid-containing Acyline derivatives. Importantly, most betide diastereomers were equipotent with Acyline. In an attempt to correlate structure and observed potency, Ramachandran-type plots were calculated for a series of betidamino acids and their methylated homologs. According to these calculations, betidamino acids have access to a more limited and distinct number of conformational states (including those associated with alpha-helices, beta-sheets, or turn structures), with deeper minima than those observed for natural amino acids.
Low Complexity, Quasi-Optimal MIMO Detectors for Iterative Receivers (2010)

We propose a novel family of Soft-Input Soft-Output detectors for iterative, point-to-point, MIMO receivers. Compared to the optimal Maximum A Posteriori receiver, low complexity is achieved restricting the detector search to small subsets of the entire QAM hyper-symbol constellation, through simple criteria. These criteria are applied to an improved version of the non-iterative Layered ORthogonal lattice Detector. We show that, notwithstanding the suboptimal low-complexity implementation, this detector approaches the EXtrinsic Information Transfer of the MAP detector. Therefore, when included in an iterative receiver it delivers the same performance. Furthermore, the deterministic complexity and highly parallelizable structure of the proposed detector are well suited for HDL and ASIC implementation. To focus on a specific setting, we consider the indoor MIMO wireless LAN 802.11n standard, taking into account errors in Channel Estimation and a frequency selective, spatially correlated channel model.
Activation of the TLR2-MyD88 pathway is required for <i>in-vivo</i> efficacy of Lipid Nanoparticle based vaccine formulation (2017)

Abstract Emerging evidence suggests that bioengineered nanoparticles can be used as immunomodulatory agents. Using murine and non-human primate vaccination models, we have identified novel cationic lipid nanoparticles (LNPs) that significantly enhance antigen-specific B-cell, CD4+T cell, and most notably, CD8+ T-cell responses. Importantly, we found that LNP-containing vaccine formulations resulted in protective efficacy in a virus challenge model, as well as, in syngeneic murine tumor models. In-vivo imaging and immunophenotyping studies showed that LNPs prolong antigen retention at the injection site and enhance antigen migration to the lymph nodes. Unbiased screening of LNPs ability to activate innate immune sensors showed that LNPs selectively activate Toll-Like Receptor-2 (TLR2). Using genetic ablation, and antibody mediated blockade, we uncovered that TLR2-MyD88 pathway is required for LNPs ability to boost immune responses in-vivo. Ex-vivo and in-vitro studies using dendritic cells (DC) showed that neutralization of TLR2 does not impact the LNP mediated increase in antigen uptake. However, LNP dependent enhancement of DC maturation, antigen processing & presentation, and chemokine production, were significantly reduced when TLR2 was neutralized. Pharmacological inhibition TIRAP, and CD14-MD2, further confirmed the need for the activation of TLR2-MyD88 pathway in LNP’s functionality. Future studies are aimed at utilizing chosen Merck chemical inhibitors of innate immune kinases to further interrogate the TLR2-MyD88 pathway’s involvement in LNP functionality. Such detailed knowledge of LNP’s mode of action will significantly influence the future design of LNPs for vaccines and immune oncology applications.
Experimental Realization of Magnetic-Free Topological Insulator Laser (2018)

We demonstrate a nonmagnetic topological insulator laser exhibiting topologically-protected transport. The topological properties of the system give rise to single mode lasing, robustness against fabrication defects, and higher slope efficiencies compared to its trivial counterpart.
The Development and Retrospective Testing of an Electroencephalographic Seizure Quality–Based Stimulus Dosing Paradigm With ECT (2000)

The optimization of electroconvulsive therapy (ECT) stimulus dosing remains uncertain. Previous work suggests the potential utility of ictal EEG models of seizure adequacy, but such models have never been tested for their ability to improve the clinical dosing of ECT treatments. Using data from 149 depressed patients, the authors developed an ictal electroencephalographic (EEG) model that can discriminate seizures produced by more therapeutically effective and less efficacious types of stimuli. They retrospectively determined how stimulus dosing according to this seizure adequacy-based model would have differed from that actually used in an additional 61 patients who received ECT according to a standard clinical dose-titration and EEG seizure duration-based dosing strategy. Although the model indicated an increase in stimulus intensity at some point during the ECT treatment course in 23 of 61 patients, only 5 of these 23 actually received a clinical increase in stimulus intensity. The patients who did not receive this increase had a significantly diminished therapeutic response compared with the other patients. Conversely, the model also indicated that an increase in stimulus intensity that occurred clinically might have been unnecessary to achieve therapeutic efficacy in 11% of the patients. This study provides preliminary evidence that ictal EEG models have the potential to make clinically relevant seizure adequacy distinctions among ECT treatments. Further prospective work is indicated to determine the clinical utility of such models.
Fast reconstruction for multichannel compressed sensing using a hierarchically semiseparable solver (2014)

The proposed HSS-Inverse method is highly efficient and should enable real-time CS reconstruction on standard MRI vendors' computational hardware.
Manganese-zinc ferrite processing, properties and recording performance (1978)

This paper discusses a multistage sintering process for the fabrication of low porosity MnZn ferrite. For the composition (in mole percent) Fe <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> O <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</inf> , 52; MnO, 25; ZnO, 23 porosities <1% were obtainable with magnetic properties at 3.2 MHz of 1076 (u'), 1520 (u") and induction of 3588 G (B <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">10</inf> ). Additionally, for 3330 type recording heads, 55% signal improvement was observed at 3.2 MHz compared to NiZn ferrite.
Hydrolytic Susceptibility of Dithioester Chain Transfer Agents and Implications in Aqueous RAFT Polymerizations (2004)

The controlled radical polymerization (CRP) technique reversible addition−fragmentation chain transfer (RAFT) has potential for preparing functional (co)polymers directly in an aqueous environment. Hydrolysis and aminolysis can eliminate the active end groups necessary for maintaining “livingness” in water. These reactions have not previously been evaluated with respect to their effect on aqueous RAFT polymerizations. Herein we determine rate constants of hydrolysis and aminolysis for representative water-soluble chain transfer agents (CTAs) cyanopentanoic acid dithiobenzoate (CTP) and the macro-chain-transfer agents (macro-CTAs) of poly(sodium 2-acrylamido-2-methylpropanesulfonate) (AMPSX) and poly(acrylamide) (AMX) at selected pH values. Rates of hydrolysis and aminolysis both increase with increasing pH and decrease with increasing molecular weight of the dithioester. On the basis of these rate constants, mathematical relationships have been developed to predict the number of living chain ends and the molecular weight with competitive hydrolysis. Utilizing this approach, predictions of molecular weight at specific conversions are in agreement with experimental values determined by SEC/MALLS.
Tyrosine Increases Blood Pressure in Hypotensive Rats (1981)

Administration of tyrosine, the amino acid precursor of catecholamines, increased blood pressure 38 to 49 percent in rats made acutely hypotensive by hemorrhage; other large neutral amino acids were ineffective. Tyrosine's effect was abolished by adrenalectomy, suggesting that, in hypotensive animals, it acts by accelerating the peripheral synthesis and release of catecholamines.
Interpolymer from starch xanthate and polyamide–polyamine–epichlorohydrin resin: Structure and papermaking application (1973)

Abstract The efficacy of oxidatively crosslinked starch xanthate for improving wet‐ and dry‐strength properties of paper prompted the present study of an alternative, interpolymeric crosslinking procedure. Sodium starch xanthate of degrees of substitution 0.05–0.25 was reacted with a commercial paper additive (a polyamide–polyamine–epichlorohydrin wet‐strength resin) which was found to contain 3‐hydroxyazetidinium chloride, epoxy‐propyl, and chlorohydrin groups (3:1:1) to give an interpolymer crosslinked by both ionic and covalent bonds. Model systems, in conjunction with nuclear magnetic resonance, infrared, and ultraviolet spectral data, served to elucidate reaction mechanisms and structures of the interpolymer and the commercial resin. Reaction conditions that favored formation of either ionic (polysalt) or covalent (xanthate ester) crosslinks were investigated. In preliminary evaluations, incorporation of the interpolymer into paper handsheets resulted in excellent wet‐ and dry‐strength improvements.
Effects of mutations on enzyme activity and immunoreactivity of the S1 subunit of pertussis toxin (1989)

By introducing a series of six different substitutions at and around position 9, we investigated the structural requirements of the amino-terminal region of the S1 subunit of pertussis toxin for both enzyme activity and immunoreactivity. All mutant S1 analogs with a substitution at this location exhibited severely decreased ADP-ribosyltransferase activity (range, 400- to 2,500-fold). In contrast, alteration of arginine 58 had considerably less effect. The reactivity of the mutant molecules with monoclonal antibody 1B7 varied with the nature of the substitution. These findings indicate an absolute requirement for the presence of an arginine residue at position 9 for the maintenance of efficient ADP-ribosyltransferase activity and illustrate the specific participation of vicinal residues in the formation of the protective epitope.
Horse erythrocyte glycoprotein-latex reagent that reacts with infectious mononucleosis heterophile antibody (1982)

A sialoglycoprotein from horse erythrocytes was isolated in essentially homogeneous form and found to contain the neuraminidase-sensitive determinant of the horse erythrocyte for Paul-Bunnell heterophile antibodies of infectious mononucleosis. This reactivity was retained after covalent coupling of the antigen to latex particles. The latex reagent has greater stability (greater than 3 years) than either fresh or preserved horse erythrocytes. It can be used in a direct slide test; no absorption of the serum is necessary. The new test compared favorably with some standard tests for infectious mononucleosis antibody which use horse erythrocytes. Agreement of the latex test with the absorbed fresh horse cell test was 100%, and agreement with a stabilized horse erythrocyte spot test was 94%. The latex test also agreed 100% with a radioimmunoassay for the detection of heterophile antibody with 125I-labeled horse erythrocyte glycoprotein. The new latex test was compared with a bovine erythrocyte glycoprotein-latex test, and a correlation of 94% was observed. In addition, it was compared with the Wöllner test (enzyme-treated sheep cell-absorbed sheep cell agglutination test) with which it agreed in 92% of samples tested.
Measurement of the density of a two-phase fluid (1992)

This patent describes an apparatus for measuring the average density of an essentially transparent, dispersed two-phase fluid having a dispersed phase made up of essentially transparent bubbles, droplets, or particles that have smooth, rounded surfaces. It comprises: a source which produces a collimated beam that has a diameter no larger than 1% of the diameter of the bubbles, droplets, or particles of the dispersed phase; a diffraction grating, to which the collimated beam is directed; means for isolating a single-order component of the diffracted beam and directing it through the dispersed two-phase fluid; containing means for the dispersed two-phase fluid that allows the single-order component of the diffracted beam to pass through, and measuring means for determining the refraction of the beam by the dispersed two-phase fluid.
Constrained Kalman filter for improving Kinect based measurements (2017)

Microsoft Kinect has the huge potential to be used in home-based rehabilitation and clinical assessments for patients suffering from stroke or other neurological disorder, due to its affordability and unobtrusiveness in analysing joint kinematics. However, skeleton data obtained from Kinect Xbox 360 (Kinect 1) or Kinect Xbox One (Kinect 2) are usually noisy which affects accuracy of estimation of three dimensional joint locations. The noise profile varies for both stationary and dynamic postures and it affects anthropometric measurements of the body segments connecting any two joints. We propose a novel approach to constrain a standard Kalman filter, based on the dynamics of individual joints, in order to keep the distance between any two physically connected joints (namely bone length) constant over time. Our constrained Kalman filter method not only tracks the joints accurately but also reduces the variation in bone lengths by 92% and 94% for Kinect 2 and 1 respectively.
PaDY: Human-friendly/cooperative working support robot for production site (2010)

In this paper, we propose a novel human-friendly/cooperative working support robot named PaDY (intime Parts/tools Delivery to You robot). This system reduces the worker's load and improves work efficiency by recognizing the worker's behavior at a production site, and supporting the worker. We propose a method estimating the pace of work of a worker so as to adjust the motion of the robot to the pace of work, and confirm its effectiveness by performing experiments. We describe the concept of PaDY, the measurement of a worker's motion for motion planning of the robot arm, and the method of estimating the pace of work based on statistical data.
Rate-Compatible Protograph-based LDPC Codes for Inter-Symbol Interference Channels (2013)

This letter produces a family of rate-compatible protograph-based LDPC codes approaching the independent and uniformly distributed (i.u.d.) capacity of inter-symbol interference (ISI) channels. This problem is highly nontrivial due to the joint design of structured (protograph-based) LDPC codes and the state structure of ISI channels. We describe a method to design nested high-rate protograph codes by adding variable nodes to the protograph of a lower rate code. We then design a family of rate-compatible protograph codes using the extension method. The resulting protograph codes have iterative decoding thresholds close to the i.u.d. capacity. Our results are supported by numerical simulations.
Adding OWL-S Support to the Existing UDDI Infrastructure (2006)

Although universal description, discovery and integration (UDDI) is the de jure Web service registry standard, it is not suitable for handling semantic markups due to its flat data model and limited search capabilities. In this paper, we introduce an approach to support semantic service descriptions and queries using registries that conform to the UDDI version 3 specification. Specifically, we present a scheme that allows users to store OWL-S service descriptions in the UDDI data model and use that information to perform semantic query processing. Our approach does not require any modification to the existing UDDI registries. The add-on modules only reside on the client-side machines that wish to take advantage of the semantic capabilities. This approach is completely backward compatible and can integrate seamlessly into the existing service-oriented architecture (SOA) infrastructure