gebhart/patrepeval huggingface dataset:
Continuous Polymer Nanocoating on Silica Nanoparticles (2014)

Continuous polymer coating of nanoparticles is of interest in many industries such as pharmaceuticals, cosmetics, food, and electronics. Here we introduce a polymer coating/precipitation technique to achieve a uniform and controllable nanosize polymer coating on nanoparticles in a continuous manner. The utility of this technique is demonstrated by coating Aerosil silica nanoparticles (SNPs) of diameter 12 nm with the polymer Eudragit RL 100. Both hydrophilic and hydrophobic SNPs were successfully coated. After determining the cloud point of an acetone solution of the polymer containing a controlled amount of the nonsolvent water, the solid hollow fiber cooling crystallization (SHFCC) technique was employed to continuously coat SNPs with the polymer. A suspension of the SNPs in an acetone-water solution of the polymer containing a surfactant was pumped through the lumen of solid polypropylene hollow fibers in a SHFCC device; cold liquid was circulated on the shell side. Because of rapid cooling-induced supersaturation and heterogeneous nucleation, precipitated polymers will coat the nanoparticles. The thickness and morphology of the nanocoating and the particle size distribution of the coated SNPs were analyzed by scanning transmission electron microscopy (STEM) with electron energy loss spectroscopy (EELS), thermogravimetric analysis (TGA), and dynamic light scattering (DLS). Results indicate that uniformly polymer-coated SNPs can be obtained from the SHFCC device after suitable post-treatments. The technique is also easily scalable by increasing the number of hollow fibers in the SHFCC device.
On exploiting diversity and spatial reuse in relay-enabled wireless networks (2008)

Relay-enabled wireless networks (eg. WIMAX 802.16j) represent an emerging trend for the incorporation of multi-hop networking solutions for last-mile broadband access in next generation wireless networks. The adoption of more sophisticated access technologies such as OFDM (orthogonal frequency division multiplexing) coupled with the relay-induced two-hop nature, provides two key benefits to these networks in the form of diversity and spatial reuse gains. However, leveraging these benefits calls for more sophisticated solutions, among which, user scheduling forms a key component.
Low Dielectric Constants of Soluble Polyimides Based on Adamantane (1997)

This work synthesizes new adamantane-based polyimides by reacting 1,3-bis[4-(4-aminophenoxy)phenyl]adamantane (4) with various aromatic tetracarboxylic dianhydrides. The poly(amic acid)s have number-average molecular weights (Mn) of 39 000−139 000. The Mn's of soluble polyimides 7d and 7e are 108 000 and 89 000, respectively. These films have low dielectric constants ranging from 2.77 to 2.91 and low moisture absorptions of less than 0.46%. Two of these polyimides have good solubilities, and even nonfluorinated polyimide 7e can be soluble in chloroform. All polyimides 7 formed tough and transparent films. These films have tensile strengths of 88.2−113.5 MPa, elongations to break of 5.6−12.5%, and initial moduli of 2.0−2.2 GPa. Dynamic mechanical analysis (DMA) reveals that adamantane-based polyimides have two relaxations on the temperature scale between 0 and 350 °C. The subglass relaxations of polyimides 7 do not occur at the same temperature; instead, they range from 100 to 175 °C. Differential scanning calorimetry (DSC) and DMA reveal their glass transition temperatures (Tg's) were found to be 232−330 and 262−343 °C, respectively. These Tg's lie in a manageable temperature range for processing in melt.
<i>Ex Vivo</i> production of platelets from stem cells (2014)

Stem cell technology holds great promise for transfusion medicine, and generation of platelets from stem cells would be transformative. Platelet transfusions are life saving for millions of people and the clinical demand for platelets continues to increase: there is a real need to increase the supply of platelets. Accordingly, there is great interest in the potential of producing platelets from stem cells for clinical use. There has been initial success in ex vivo generation of platelets from stem cells using cord blood stem cells, embryonic stem cells and induced pluripotent stem cells. However, the platelet yields achieved by these strategies have not been sufficient for clinical purposes. This review provides updated information about the current strategies of ex vivo generation of platelets. Megakaryocytopoiesis and platelet generation, along with the importance of genetic determinants of these processes, are reviewed in the context of efforts to generate these products from stem cells. Current challenges and rate-limiting steps in ex vivo platelet generation are discussed, together with strategies to overcome them. While much work remains, great progress has been made, moving ex vivo generation of platelets ever closer to the clinic.
Portable Multispectral Imaging Instrument for Food Industry* (2008)

The overall goal of this paper is to develop a cost effective portable multispectral imaging instrument that inspectors or plant personnel can use for quality control. Food safety and quality in food industry, especially small plant is ongoing problem. Identification and separation of contaminated food is very important to protect the consumer from a potential source of food poisoning. The current methods of inspecting food quality and safety, however, is mostly done by human visual observation with the criteria of color, consistency, and composition used for identification. Therefore, there is a need to develop instrumental methods which can reduce inspector fatigue, variability, insure continuous inspection, and provide a safe and high quality food supply for the consumer. The development of a portable multispectral instrument for contaminant detection is able to improve food safety and quality inspection in identifying, developing, and validating imaging technologies that are economically viable, especially for small food processing plants to help them meet food safety requirements. As an example of multispectral imaging application, we designed and fabricated a portable multispectral instrument to collect and analyze spectra for real-time contaminant detection for small poultry processing plant. Specifically, the procedure to develop a portable multispectral instrument including sensor design, fabrication, calibration, data collection, analysis, algorithm development for detecting poultry fecal contaminants in real-time was demonstrated.
A miniaturized 3D printed quadrifilar helix antenna with a conical ground plane (2017)

This paper presents a miniaturized quadrifilar helix antenna. The miniaturization is based on merging two different approaches. The first one is related to the loading of the tip of the four helical arms by circular elements. The incorporation of dielectric slabs within the empty space between the antenna arms constitute the second approach. The effect of changing the antenna's planar ground plane into a conical volumetric shape is studied as well. The fabricated prototype using 3D printing technology features good analogy with the simulated design.
N-fluoro perfluoroalkylsulphonimides: efficient reagents for the fluorination of 1,3-dicarbonyl derivatives (1991)

Z. Xu, D. D. DesMarteau and Y. Gotoh, J. Chem. Soc., Chem. Commun., 1991, 179 DOI: 10.1039/C39910000179
Design of a High Performance Thin All-Solid-State Supercapacitor Mimicking the Active Interface of Its Liquid-State Counterpart (2013)

Here we report an all-solid-state supercapacitor (ASSP) which closely mimics the electrode-electrolyte interface of its liquid-state counterpart by impregnating polyaniline (PANI)-coated carbon paper with polyvinyl alcohol-H2SO4 (PVA-H2SO4) gel/plasticized polymer electrolyte. The well penetrated PVA-H2SO4 network along the porous carbon matrix essentially enhanced the electrode-electrolyte interface of the resulting device with a very low equivalent series resistance (ESR) of 1 Ω/cm(2) and established an interfacial structure very similar to a liquid electrolyte. The designed interface of the device was confirmed by cross-sectional elemental mapping and scanning electron microscopy (SEM) images. The PANI in the device displayed a specific capacitance of 647 F/g with an areal capacitance of 1 F/cm(2) at 0.5 A/g and a capacitance retention of 62% at 20 A/g. The above values are the highest among those reported for any solid-state-supercapacitor. The whole device, including the electrolyte, shows a capacitance of 12 F/g with a significantly low leakage current of 16 μA(2). Apart from this, the device showed excellent stability for 10000 cycles with a coulombic efficiency of 100%. Energy density of the PANI in the device is 14.3 Wh/kg.
Evaluation of Soybean Germplasm for Resistance to <i>Phakopsora pachyrhizi</i> (2006)

Phakopsora pachyrhizi, the causal fungus of soybean rust, was discovered in the continental U.S. in November 2004. The presence of this disease in the U.S. may have an impact on soybean (Glycine max) production, as the current commercial varieties are considered to be susceptible, and the use of one or more applications of fungicides will add additional costs to production. One objective of the USDA-ARS research on soybean rust is to identify soybean germplasm with resistance to the disease. There are over 16,000 soybean accessions in the USDA Germplasm Collection located at the University of Illinois. These accessions were evaluated in a two-tiered inoculation program using a mixture of four P. pachyrhizi isolates in Biosafety Level 3 containment greenhouses the FDWSRU. In the first round of evaluations, 16,595 accessions were rated for rust severity. Of these, 3,215 accessions, based on low visual rust severity or the presence of a red-brown reaction, were selected for a second round of evaluation. After the second round of replicated evaluations of the 3,215 accessions, 805 were selected for further evaluation, again based on low mean visual severity or the presence of a red-brown reaction. Some of these selected accessions have the potential to provide soybean rust resistance genes that may be useful for incorporation into commercial soybean cultivars. Accepted for publication 9 November 2005. Published 4 January 2006.
Efficient Java Communication Libraries over InfiniBand (2009)

This paper presents our current research efforts on efficient Java communication libraries over InfiniBand. The use of Java for network communications still delivers insufficient performance and does not exploit the performance and other special capabilities (RDMA and QoS) of high-speed networks, especially for this interconnect. In order to increase its Java communication performance, InfiniBand has been supported in our high performance sockets implementation, Java Fast Sockets (JFS), and it has been greatly improved the efficiency of Java Direct InfiniBand (Jdib), our low-level communication layer, enabling zero-copy RDMA capability in Java. According to our experimental results, Java communication performance has been improved significantly, reducing start-up latencies from 34 mus down to 12 and 7 mus for JFS and Jdib, respectively, whereas peak bandwidth has been increased from 0.78 Gbps sending serialized data up to 6.7 and 11.2 Gbps for JFS and Jdib, respectively. Finally, it has been analyzed the impact of these communication improvements on parallel Java applications, obtaining significant speedup increases of up to one order of magnitude on 128 cores.
A novel shape-based diagnostic approach for early diagnosis of lung nodules (2011)

An alternative method of diagnosing malignant lung nodules by their shape rather than conventional growth rate is proposed. The 3D surfaces of the detected lung nodules are delineated by spherical harmonic analysis that represents a 3D surface of the lung nodule supported by the unit sphere with a linear combination of special basis functions, called spherical harmonics (SHs). The proposed 3D shape analysis is carried out in five steps: (i) 3D lung nodule segmentation with a deformable 3D boundary controlled by two probabilistic visual appearance models (the learned prior and the estimated current appearance one); (ii) 3D Delaunay triangulation to construct a 3D mesh model of the segmented lung nodule surface; (iii) mapping this model to the unit sphere; (iv) computing the SHs for the surface; and (v) determining the number of the SHs to delineate the lung nodule. We describe the lung nodule shape complexity with a new shape index, the estimated number of the SHs, and use it for the K-nearest classification into malignant and benign lung nodules. Preliminary experiments on 109 lung nodules (51 malignant and 58 benign) resulted in the 94.4% correct classification (for the 95% confidence interval), showing the proposed method is a promising supplement to current technologies for the early diagnosis of lung cancer.
Induction of monocyte chemoattractant protein-1 in HIV-1 Tat-stimulated astrocytes and elevation in AIDS dementia (1998)

Activated monocytes release a number of substances, including inflammatory cytokines and eicosanoids, that are highly toxic to cells of the central nervous system. Because monocytic infiltration of the central nervous system closely correlates with HIV-1-associated dementia, it has been suggested that monocyte-derived toxins mediate nervous system damage. In the present study, we show that the HIV-1 transactivator protein Tat significantly increases astrocytic expression and release of monocyte chemoattractant protein-1 (MCP-1). Astrocytic release of beta-chemokines, which are relatively less selective for monocytes, including RANTES, macrophage inflammatory protein-1alpha, and macrophage inflammatory protein-1beta, was not observed. We also show that MCP-1 is expressed in the brains of patients with HIV-1-associated dementia and that, of the beta-chemokines tested, only MCP-1 could be detected in the cerebrospinal fluid of patients with this condition. Together, these data provide a potential link between the presence of HIV-1 in the brain and the monocytic infiltration that may substantially contribute to dementia.
Measuring Cerebrovascular Reactivity: The Dynamic Response to a Step Hypercapnic Stimulus (2015)

We define cerebral vascular reactivity (CVR) as the ratio of the change in blood oxygen level-dependent (BOLD) magnetic resonance imaging (MRI) signal (S) to an increase in blood partial pressure of CO2 (PCO2): % Δ S/Δ PCO2 mm Hg. Our aim was to further characterize CVR into dynamic and static components and then study 46 healthy subjects collated into a reference atlas and 20 patients with unilateral carotid artery stenosis. We applied an abrupt boxcar change in PCO2 and monitored S. We convolved the PCO2 with a set of first-order exponential functions whose time constant τ was increased in 2-second intervals between 2 and 100 seconds. The τ corresponding to the best fit between S and the convolved PCO2 was used to score the speed of response. Additionally, the slope of the regression between S and the convolved PCO2 represents the steady-state CVR (ssCVR). We found that both prolongations of τ and reductions in ssCVR (compared with the reference atlas) were associated with the reductions in CVR on the side of the lesion. τ and ssCVR are respectively the dynamic and static components of measured CVR.
Designing Liquid Metal Interfaces to Enable Next Generation Flexible and Reconfigurable Electronics (2017)

Gallium liquid metal alloys are room temperature fluidic conductors that are used to create a variety of paradigm shifting concepts in stretchable and reconfigurable electronics. A viscoelastic solid oxide skin encases the bulk liquid metal alloy which allows remarkably unprecedented 3D fluidic structures to be constructed. This oxide also has detrimental effects to fluidic behavior in microchannels because it adheres to the channel walls. The work mitigates these detrimental effects in flow behavior through surface modification of the gallium oxide with phosphonic acids to control interfacial chemistry. This results in no adhesion between the gallium surface oxide and the underlying substrates and no alloying with metal electrodes, two pervasive problems in the field. In addition to control over the flow properties of the metal alloy with the oxide intact, phosphonic acid modification allows tunability of the work function and surface oxide thickness.
Coordinated management of power usage and runtime performance (2008)

With the continued growth of computing power and reduction in physical size of enterprise servers, the need for actively managing electrical power usage in large datacenters is becoming ever more pressing. By far the greatest savings in electrical power can be effected by dynamically consolidating workload onto the minimum number of servers needed at a given time and powering off the remainder. However, simple schemes for achieving this goal fail to cope with the complexities of realistic usage scenarios. In this paper we present a combined power-and performance-management system that builds on a state-of-the-art performance manager to achieve significant power savings without unacceptable loss of performance. In our system, the degree to which performance may be traded off against power is itself adjustable using a small number of easily-understood parameters, permitting administrators in different facilities to select the optimal tradeoff for their needs. We characterize the power saved, the effects of the tradeoff between power and performance, and the changes in behavior as the tradeoff parameters are adjusted, both in simulation and in a sample deployment of the real system.
Photocurrent-Generating Properties of Organometallic Fullerene Molecules on an Electrode (2008)

Compact, rigid, five-legged fullerene derivatives C60R5Me and M(C60R5)Cp (M = Fe and Ru; R = C6H4COOH, C6H4C6H4COOH, and CH2COOH) were synthesized and arrayed on an indium-tin oxide (ITO) surface. These devices exhibit a respectable quantum yield with photocurrent generation up to 18%, and, more importantly, the direction of the photocurrent can be changed not only by the molecular structure itself but also by changing the geometric configuration of the photoactive acceptor (fullerene) and donor (metal atom) on the ITO surface.
Functional Cloning, Heterologous Expression, and Purification of Two Different N-Deoxyribosyltransferases fromLactobacillus helveticus (2002)

Lactobacillus helveticus contains two types of N-deoxyribosyltransferases: DRTase I catalyzes the transfer of 2'-deoxyribose between purine bases exclusively whereas DRTase II is able to transfer the 2'-deoxyribose between two pyrimidine or between pyrimidine and purine bases. An Escherichia coli strain, auxotrophic for guanine and unable to use deoxyguanosine as source of guanine, was constructed to clone the corresponding genes. By screening a genomic bank for the production of guanine, the L. helveticus ptd and ntd genes coding for DRTase I and II, respectively, were isolated. Although the two genes have no sequence similarity, the two deduced polypeptides display 25.6% identity, with most of the residues involved in substrate binding and the active site nucleophile Glu-98 being conserved. Overexpression and purification of the two proteins shows that DRTase I is specific for purines with a preference for deoxyinosine (dI) > deoxyadenosine > deoxyguanosine as donor substrates whereas DRTase II has a strong preference for pyrimidines as donor substrates and purines as base acceptors. Purine analogues were substrates as acceptor bases for both enzymes. Comparison of DRTase I and DRTase II activities with dI as donor or hypoxanthine as acceptor and colocalization of the ptd and add genes suggest a specific role for DRTase I in the metabolism of dI.
Islet cell cytoplasmic autoantibody reactivity to glutamate decarboxylase in insulin-dependent diabetes. (1993)

Individuals with or at risk for insulin-dependent diabetes (IDD) frequently have autoantibodies against an islet cell cytoplasmic (ICA) antigen thought to be a sialoglycolipid. However, we now report that preabsorption of ICA-positive sera with recombinant glutamate decarboxylase (human GAD 65 and/or GAD 67) reduced or blocked the ICA reactivity of 5/18 (27%) new-onset IDD patients and 7/18 (39%) prediabetics. Interestingly, nondiabetic subjects with ICA of > or = 5 yr in duration had GAD-reactive ICA significantly more often (16/24, 67%, P < 0.04) than the diabetic groups. ICA reactivity to GAD was not related to serum ICA titer nor the age of the individual, and in all cases tested was blocked by GAD 65 or GAD 67 with equivalent efficiency. The ICA observed in 21/25 (84%) IDD patients with ICA long after clinical onset of disease (9-42 yr) was reactive to GAD. A natural history analysis of three individuals showed conversions from ICA which was reactive to GAD to a non-GAD-reactive ICA nearer to their clinical onsets of IDD. This study further defines the autoantigens reactive to ICA, and suggests that, whereas ICA that are not reactive to GAD may identify an advanced and more prognostic lesion, GAD-reactive ICA may typify the early or inductive lesion that may or may not progress to clinically significant beta cell injury.
Design Considerations for Switched Reluctance Machines With a Higher Number of Rotor Poles (2011)

Switched-reluctance-machine (SRM) technology is a potential candidate for the propulsion systems of hybrid and plug-in hybrid electric vehicles. They are robust in harsh operational conditions and have a wide constant power speed range. Conventional SRM configurations have a higher number of stator poles than rotor poles. This paper presents the advantages of a novel SRM configuration with the number of rotor poles greater than the number of stator poles. It also investigates different design challenges toward the traction applications. The proposed SRM configuration is based on a pole-design formula. Geometrical design equations and related challenges are introduced, and their applicability has been verified on a three-phase 6/10 SRM using finite-element-analysis simulations.
The Actinobacillus pleuropneumoniae hemolysin determinant: unlinked appCA and appBD loci flanked by pseudogenes (1991)

The appBD genes encoding the secretion functions for the 110-kDa RTX hemolysin of Actinobacillus pleuropneumoniae have been cloned and sequenced. Unlike analogous genes from other RTX determinants, the appBD genes do not lie immediately downstream from the hemolysin structural gene, appA. Although isolated from a diverse group of gram-negative organisms, the appBD genes and the characterized RTX BD genes from other organisms all exhibit a high degree of homology at both the DNA and predicted amino acid sequence levels. Analysis of the DNA sequences 3' to appA and 5' to appB suggests that these regions harbor remnant RTX B and A pseudogenes, respectively. Although the appA gene is most similar to the lktA gene from Pasteurella haemolytica (Y. F. Chang, R. Young, and D. K. Struck, DNA 8:635-647, 1989), the RTX A pseudogene upstream from appB most closely resembles the hlyB gene from Escherichia coli, suggesting that the appCA and appBD operons were derived from different ancestral RTX determinants.