gebhart/patrepeval huggingface dataset:
DAO Object Model: The Definitive Reference (2000)

Preface 1. Introduction Early and Late Binding The Object Models for Working with Access The Visual Basic Dialects 2. DBEngine Object DBEngine Properties DBEngine Methods 3. Errors Collection and Error Object Errors Collection Properties Errors Collection Methods Error Object Properties 4. Workspaces Collection and Workspace Object Workspaces Collection Properties Workspaces Collection Methods Workspace Object Properties Workspace Object Methods 5. Databases Collection and Database Object Databases Collection Properties Databases Collection Methods Database Object Properties Database Object Methods 6. Containers Collection and Container Object Containers Collection Properties Containers Collection Methods Container Object Properties 7. QueryDefs Collection and QueryDef Object QueryDefs Collection Properties QueryDefs Collection Methods QueryDef Object Properties QueryDef Object Methods 8. Recordsets Collection and Recordset Object Recordsets Collection Properties Recordsets Collection Methods Recordset Object Properties Recordset Object Methods 9. Relations Collection and Relation Object Relations Collection Properties Relations Collection Methods Relation Object Properties Relation Object Methods 10. TableDefs Collection and TableDef Object TableDefs Collection Properties TableDefs Collection Methods TableDef Object Properties TableDef Object Methods 11. Groups Collection and Group Object Groups Collection Properties Groups Collection Methods Group Object Properties Group Object Methods 12. Users Collection and User Object Users Collection Properties Users Collection Methods User Object Properties User Object Methods 13. Fields Collection and Field Object Fields Collection Properties Fields Collection Methods Field Object Properties Field Object Methods 14. Parameters Collection and Parameter Object Parameters Collection Properties Parameters Collection Methods Parameter Object Properties 15. Indexes Collection and Index Object Indexes Collection Properties Indexes Collection Methods Index Object Properties Index Object Methods 16. Properties Collection and Property Object Properties Collection Properties Properties Collection Methods Property Object Properties A. Object Model Browser B. Object Model Browser Reference Index
Convolutional Neural Pyramid for Image Processing (2017)

We propose a principled convolutional neural pyramid (CNP) framework for general low-level vision and image processing tasks. It is based on the essential finding that many applications require large receptive fields for structure understanding. But corresponding neural networks for regression either stack many layers or apply large kernels to achieve it, which is computationally very costly. Our pyramid structure can greatly enlarge the field while not sacrificing computation efficiency. Extra benefit includes adaptive network depth and progressive upsampling for quasi-realtime testing on VGA-size input. Our method profits a broad set of applications, such as depth/RGB image restoration, completion, noise/artifact removal, edge refinement, image filtering, image enhancement and colorization.
New solid-state chemistry technologies to bring better drugs to market: knowledge-based decision making (2007)

Modern drug development demands constant deployment of more effective technologies to mitigate the high cost of bringing new drugs to market. In addition to cost savings, new technologies can improve all aspects of pharmaceutical development. New technologies developed at SSCI, Inc. include solid form development of an active pharmaceutical ingredients. (APIs) are PatternMatch software and capillary-based crystallisation techniques that not only allow for fast and effective solid form screening, but also extract maximum property information from the routine screening data that is generally available. These new technologies offer knowledge-based decision making during solid form development of APIs and result in more developable API solid forms.
Feasibility of Using Optical Sensing to Measure Bore Depth in Surgical Bone Drilling (2018)

The depth gauge is used in many osteosynthesis surgeries to measure drilled bore depth for screw selection, and has significant limitations. Its use has been shown to contribute to placement of incorrectly sized screws, which can lead to adverse outcomes in patients. We have developed an automatic depth gauge prototype which mounts on an existing surgical drill and makes use of an optical sensor. This builds off previous work in our lab which showed that drilled bore depth could be computed from continuous measurement of drill displacement relative to the bone. We tested our device in animal models and compared it with digital calipers as a gold standard. In a simple porcine model the prototype showed potentially superior performance (mean error 2.05mm, SD 0.67mm) compared with the conventional depth gauge (mean error 0.83 mm, SD 1.55 mm). However, this could not be reproduced in a more realistic porcine model.An automated depth gauge mounted on a conventional surgical drill shows potential as a replacement for the existing depth gauge, but the design needs to be refined for use in an operating room setting.
Surface-supported metal cluster carbonyls. Chemisorption decomposition and reactivity of hexadecacarbonylhexarhodium supported on alumina, silica-alumina, and magnesia (1979)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSurface-supported metal cluster carbonyls. Chemisorption decomposition and reactivity of hexadecacarbonylhexarhodium supported on alumina, silica-alumina, and magnesiaA. K. Smith, F. Hugues, A. Theolier, J. M. Basset, R. Ugo, G. M. Zanderighi, J. L. Bilhou, and W. F. GraydonCite this: Inorg. Chem. 1979, 18, 11, 3104–3112Publication Date (Print):November 1, 1979Publication History Published online1 May 2002Published inissue 1 November 1979https://pubs.acs.org/doi/10.1021/ic50201a030https://doi.org/10.1021/ic50201a030research-articleACS PublicationsRequest reuse permissionsArticle Views260Altmetric-Citations149LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Rapid PCR-Based Detection of <b> <i>Streptococcus pneumoniae</i> DNA in Cerebrospinal Fluid </b> (1999)

The reports by Cherin et al. (2) and Garcia et al. (3) document the potential advantages of PCR-based assays for the detection of Streptococcus pneumoniae DNA in cerebrospinal fluid (CSF) and lung tissue, particularly when culture is compromised by antibiotic therapy. In both instances the (different) PCR-enzyme immunoassays (PCR-EIAs) showed excellent sensitivity, detecting approximately 3 CFU and 2 to 27 CFU, respectively.
Implementation of templated DSA for via layer patterning at the 7nm node (2015)

In recent years major advancements have been made in the directed self-assembly (DSA) of block copolymers (BCP). Insertion of DSA for IC fabrication is seriously considered for the 7nm node. At this node the DSA technology could alleviate costs for double patterning and limit the number of masks that would be required per layer. At imec multiple approaches for inserting DSA into the 7nm node are considered. One of the most straightforward approaches for implementation would be for via patterning through templated DSA (grapho-epitaxy), since hole patterns are readily accessible through templated hole patterning of cylindrical phase BCP materials. Here, the pre-pattern template is first patterned into a spin-on hardmask stack. After optimizing the surface properties of the template the desired hole patterns can be obtained by the BCP DSA process. For implementation of this approach to be implemented for 7nm node via patterning, not only the appropriate process flow needs to be available, but also appropriate metrology (including for pattern placement accuracy) and DSA-aware mask decomposition are required. In this paper the imec approach for 7nm node via patterning will be discussed.
Yet another mesh array smart sensor? (2003)

Describes the architecture of a mesh array smart sensor, in close relation with the algorithms to be carried out by it. On the one hand, a monolithic implementation of the mesh array is a logical consequence of its design requirements within the framework of full custom integration. On the other hand, today's implementations are limited to Boolean picture processing and binary picture memorization if sensible size pictures are to be handled. Nevertheless, the validity of these choices is confirmed by a 50-mm/sup 2/ area (60*60PE) chip which has been laid out in a 2- mu m two-metal CMOS technology.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A vimentin binding small molecule leads to mitotic disruption in mesenchymal cancers (2017)

Expression of the transcription factor FOXC2 is induced and necessary for successful epithelial-mesenchymal transition, a developmental program that when activated in cancer endows cells with metastatic potential and the properties of stem cells. As such, identifying agents that inhibit the growth of FOXC2-transformed cells represents an attractive approach to inhibit chemotherapy resistance and metastatic dissemination. From a high throughput synthetic lethal screen, we identified a small molecule, FiVe1, which selectively and irreversibly inhibits the growth of mesenchymally transformed breast cancer cells and soft tissue sarcomas of diverse histological subtypes. FiVe1 targets the intermediate filament and mesenchymal marker vimentin (VIM) in a mode which promotes VIM disorganization and phosphorylation during metaphase, ultimately leading to mitotic catastrophe, multinucleation, and the loss of stemness. These findings illustrate a previously undescribed mechanism for interrupting faithful mitotic progression and may ultimately inform the design of therapies for a broad range of mesenchymal cancers.
Characteristics of Potassium Permanganate Encapsulated in Polymer (2005)

Potassium permanganate was encapsulated in various polymers to create microcapsules with slow-release properties. Batch tests were conducted to evaluate the rates at which the microcapsules release permanganate. The release histories of 18 different polymer formulations varied strongly, but average initial release rate was 2.70gKMnO4 released g KMnO4initial−1d−1, and the release rate typically decreased with time. The total duration of release ranged from 3to80days, with an average of 27days. In other batch tests trichloroethene (TCE) was degraded to below detectable amounts by the microcapsules. The degradation rate for TCE was three to four times faster during the initial reaction period than predicted based on permanganate release rates. There appear to be several promising environmental applications for this method of creating a slow-release oxidant.
Printing Technology for Aramid Fabrics (1991)

Fabrics of Du Pont NOMEX aramid fiber can be printed by a conventional rotary screen printing process if the aramid fiber structure is open to allow dyes to migrate in and there is a structural feature to facilitate binding of the dye molecules to the fiber substrate. With Nomex this is achieved by imbibing surfactants into the water swollen fiber structure prior to initial drying. The surfactant provides a much more open structure as well as providing an ionic binding site for the dyes. The special problems of printing military camouflage fabrics where the colors, dye fastness properties, and infrared reflectance properties are critical are discussed.
Conventional and microwave‐assisted SPPS approach: a comparative synthesis of PTHrP(1–34)NH<sub>2</sub> (2011)

Attracted by the possibility to optimize time and yield of the synthesis of difficult peptide sequences by MW irradiation, we compared Fmoc/tBu MW-assisted SPPS of 1-34 N-terminal fragment of parathyroid hormone-related peptide (PTHrP) with its conventional SPPS carried out at RT. MWs were applied in both coupling and deprotection steps of SPPS protocol. During the stepwise elongation of the resin-bound peptide, monitoring was conducted by performing MW-assisted mini-cleavages and analyzing them by UPLC-ESI-MS. Identification of some deletion sequences was helpful to recognize critical couplings and as such helped to guide the introduction of MW irradiations to these stages.
Rapid kinetics of second messenger production in bitter taste (1996)

The tasting of bitter compounds may have evolved as a protective mechanism against ingestion of potentially harmful substances. We have identified second messengers involved in bitter taste and show here for the first time that they are rapid and transient. Using a quench-flow system, we have studied bitter taste signal transduction in a pair of mouse strains that differ in their ability to taste the bitter stimulus sucrose octaacetate (SOA); however, both strains taste the bitter agent denatonium. In both strains of mice, denatonium (10 mM) induced a transient and rapid increase in levels of the second messenger inositol 1,4,5-trisphosphate (IP3) with a maximal production near 75-100 ms after stimulation. In contrast, SOA (100 microM) brought about a similar increase in IP3 only in SOA-taster mice. The response to SOA was potentiated in the presence of GTP (1 microM). The GTP-enhanced SOA-response supports a G protein-mediated response for this bitter compound. The rapid kinetics, transient nature, and specificity of the bitter taste stimulus-induced IP3 formation are consistent with the role of IP3 as a second messenger in the chemoelectrical transduction of bitter taste.
The Sympathetic Nervous System Alterations in Human Hypertension (2015)

Several articles have dealt with the importance and mechanisms of the sympathetic nervous system alterations in experimental animal models of hypertension. This review addresses the role of the sympathetic nervous system in the pathophysiology and therapy of human hypertension. We first discuss the strengths and limitations of various techniques for assessing the sympathetic nervous system in humans, with a focus on heart rate, plasma norepinephrine, microneurographic recording of sympathetic nerve traffic, and measurements of radiolabeled norepinephrine spillover. We then examine the evidence supporting the importance of neuroadrenergic factors as promoters and amplifiers of human hypertension. We expand on the role of the sympathetic nervous system in 2 increasingly common forms of secondary hypertension, namely hypertension associated with obesity and with renal disease. With this background, we examine interventions of sympathetic deactivation as a mode of antihypertensive treatment. Particular emphasis is given to the background and results of recent therapeutic approaches based on carotid baroreceptor stimulation and radiofrequency ablation of the renal nerves.
First trimester screening of circulating C19MC microRNAs and the evaluation of their potential to predict the onset of preeclampsia and IUGR (2017)

Up-regulation of miR-517-5p, miR-518b and miR-520h was associated with a risk of later development of preeclampsia. First trimester screening of extracellular miR-517-5p identified a proportion of women with subsequent preeclampsia. No circulating C19MC microRNA biomarkers were identified that could predict later occurrence of IUGR.
Current status and advances of therapy for anal canal cancer (2010)

Objective To summarize the current status and development of therapy for canal cancer. Methods Application of Medline database and CHKD database, with anal canal cancer, chemotherapy, radiotherapy, abdominoperineal resection as key words search literature about canal cancer published from January 1996 to June 2009. Retrieval criteria: the epidemiology of canal cancer; the etiology of canal cancer; the clinical manifestation and classification of canal cancer; strategies and development of therapy for canal cancer. Sixty-seven of them met the retrieval criteria, while finally 22 related papers were analyzed. Results Over the last 30 years, treatment of canal cancer has undergone a profound evolution. Combined-modality treatment combined with chemoradiotherapy (CRT), including three-dimensional conformal radiation therapy (3D-CRT), intensity modulated radiation therapy (IMRT), novel anti-tumor agent and salvage surgery, had resulted in a 5-year survival rate of approximately 80 %. Conclusion Anal canal cancer is a rare tumor. CRT has replaced surgery as the first choice of canal cancer. The development of molecular biology will likely lead to further proposals for trials of canal cancer. 

Key words: 
Anal canal cancer;  Radiotherapy;  Chemotherapy;  Abdominoperineal resection;  Literature review
Intravesical Instillations of Interferon Gamma in the Prophylaxis of High Risk Superficial Bladder Cancer (2002)

Intravesically administered IFN gamma has a demonstrable protective role as first line adjuvant treatment in superficial bladder cancer. This role is mainly focused on prevention of recurrences in the short term. Further prospective studies with longer follow up are required, in order to define the exact place of the drug in the urologist's armamentarium.
Nonpeptide Orexin-2 Receptor Agonist Attenuates Morphine-induced Sedative Effects in Rats (2018)

Orexin-A and/or YNT-185 attenuated morphine-induced sedative effects assessed by EEG changes and behavioral measures in rats. The authors' results suggest that orexin-2 receptor activation alleviates morphine-induced sedative effects.
Identification of Inhibitors of the <i>Leishmania</i> cdc2‐Related Protein Kinase CRK3 (2011)

New drugs are urgently needed for the treatment of tropical parasitic diseases such as leishmaniasis and human African trypanosomiasis (HAT). This work involved a high-throughput screen of a focussed kinase set of ~3400 compounds to identify potent and parasite-selective inhibitors of an enzymatic Leishmania CRK3-cyclin 6 complex. The aim of this study is to provide chemical validation that Leishmania CRK3-CYC6 is a drug target. Eight hit series were identified, of which four were followed up. The optimisation of these series using classical SAR studies afforded low-nanomolar CRK3 inhibitors with significant selectivity over the closely related human cyclin dependent kinase CDK2.
Improving the Quality of Synthetic FLAIR Images with Deep Learning Using a Conditional Generative Adversarial Network for Pixel-by-Pixel Image Translation (2019)

Using deep learning, we improved the synthetic FLAIR image quality by generating FLAIR images that have contrast closer to that of conventional FLAIR images and fewer granular and swelling artifacts, while preserving the lesion contrast.
Modulation of Anaerobic Energy Metabolism of <i>Bacillus subtilis</i> by <i>arfM</i> ( <i>ywiD</i> ) (2001)

Bacillus subtilis grows under anaerobic conditions utilizing nitrate ammonification and various fermentative processes. The two-component regulatory system ResDE and the redox regulator Fnr are the currently known parts of the regulatory system for anaerobic adaptation. Mutation of the open reading frame ywiD located upstream of the respiratory nitrate reductase operon narGHJI resulted in elimination of the contribution of nitrite dissimilation to anaerobic nitrate respiratory growth. Significantly reduced nitrite reductase (NasDE) activity was detected, while respiratory nitrate reductase activity was unchanged. Anaerobic induction of nasDE expression was found to be significantly dependent on intact ywiD, while anaerobic narGHJI expression was ywiD independent. Anaerobic transcription of hmp, encoding a flavohemoglobin-like protein, and of the fermentative operons lctEP and alsSD, responsible for lactate and acetoin formation, was partially dependent on ywiD. Expression of pta, encoding phosphotransacetylase involved in fermentative acetate formation, was not influenced by ywiD. Transcription of the ywiD gene was anaerobically induced by the redox regulator Fnr via the conserved Fnr-box (TGTGA-6N-TCACT) centered 40.5 bp upstream of the transcriptional start site. Anaerobic induction of ywiD by resDE was found to be indirect via resDE-dependent activation of fnr. The ywiD gene is subject to autorepression and nitrite repression. These results suggest a ResDE --> Fnr --> YwiD regulatory cascade for the modulation of genes involved in the anaerobic metabolism of B. subtilis. Therefore, ywiD was renamed arfM for anaerobic respiration and fermentation modulator.
Transmission of one-dimensional images through a single optical fiber by time-integrated holography (2003)

In a previous paper [Opt. Express 10, 663 (2002)], the current author presented a principle and a technique allowing the transformation of a random relationship between the complex amplitudes at two wave fronts into a selective one. As the current paper shows, the same principle can be readily implemented to transmit one-dimensional images through a single multimode optical fiber.
Study of the Rectangular-Like Output Waveforms of a 720 kV Coaxial Marx Generator (1981)

The mechanism of generation of unique output voltages of a low-inductance coaxial Marx generator, developed for producing relativistic electron beams or ion beams, is investigated using an equivalent circuit in which two kinds of stray capacitance are taken into account. One of these is that which exists between each Marx module and the Marx outer conductor, and the other is that which exists between the two electrodes of the spark gap. The former capacitance is found to be useful for generating rectangular-like output voltages, which the latter capacitance is found to be harmful.
CovX‐Bodies (2013)

This chapter contains sections titled: The CovX-Body Concept Technological Aspects Applications of the CovX-Body Technology References