gebhart/patrepeval huggingface dataset:
Session Initiation Protocol firewall for the IP Multimedia Subsystem core (2011)

As the deployment of Session Initiation Protocol (SIP) accelerates, there is an accompanying need to secure the SIP infrastructure. One way to do so is through a SIP firewall, which is loosely defined as a device that blocks attacks mounted via SIP. Using this definition, a firewall is indistinguishable from a session border controller (SBC), also used by SIP service providers to secure their networks. SIP firewalls and SBCs are often deployed by SIP service providers at the periphery of the network to impose some manner of order on the SIP traffic before allowing it to enter the network. In this vein, a SIP firewall needs to effectively block many SIP attacks and distinguish a distributed denial of service (DDoS) attack from a classic overload traffic arrival rate. But what exactly is a firewall and what features should it provide in its role of inspecting SIP traffic bound for the service provider's network? What are the economic and technical tradeoffs necessary for ubiquitous deployment? In this paper, we define the role of a firewall in protecting the IP Multimedia Subsystem (IMS) or SIP-based core network, distinguish it from an SBC, and characterize the specific threats to SIP messages at the L2 (data link layer), L3 (network layer), L4 (transport layer), and L5 (session layer). We show how a SIP firewall can thwart these attacks and we propose an implementation based on a simplified, but fully hardware accelerated SIP proxy as a front end SIP firewall. Such a system naturally blocks most attacks and implements many defense mechanisms.
High-yield and environment-minded fabrication of nanoporous anodic aluminum oxide templates (2015)

High-yield and environment-minded fabrication of nanoporous AAO templates through simultaneous multi-surface anodization and direct detachment by applying stair-like reverse biases.
Optical and structural characterization of InAs/GaSb superlattices (1997)

InAs/GaSb superlattices sandwiched between conventional InAs layers were grown by low pressure metal organic chemical vapor deposition. Period and roughness of the superlattices were examined by field emission transmission electron microscopy. Room temperature infrared absorption spectra for InAs/GaSb superlattices were obtained by Fourier-transform infrared spectroscopy. The effects of varying the doping levels and thicknesses of the InAs sandwiching layers on the absorption spectra of InAs/GaSb superlattices were studied. It was found that by choice of suitable doping levels and cap/buffer thicknesses, the resulting fermi level equalization (as in normal homo or heterojunctions) thereby allowed the setting or “pinning” of the superlattice Fermi level to any desired value within the range made available by the original bulk material characteristics in conjunction with the doping conditions. When the thicknesses of the InAs sandwiching layers became less than 1 μm, the sandwiching effect and the intersubband transition decreased dramatically. The structure of the interfaces inside the superlattice was also studied. Energy dispersive spectroscopy was used to estimate interdiffusion conditions within the superlattice. The effects of different periods and purge gases on the absorption spectra were also studied.
Genes for the biosynthesis of spinosyns: applications for yield improvement in Saccharopolyspora spinosa (2001)

Spinosyns A and D are the active ingredients in an insect control agent produced by fermentation of Saccharopolyspora spinosa. Spinosyns are macrolides with a 21-carbon, tetracyclic lactone backbone to which the deoxysugars forosamine and tri-O-methylrhamnose are attached. The spinosyn biosynthesis genes, except for the rhamnose genes, are located in a cluster that spans 74 kb of the S. spinosa genome. DNA sequence analysis, targeted gene disruptions and bioconversion studies identified five large genes encoding type I polyketide synthase subunits, and 14 genes involved in sugar biosynthesis, sugar attachment to the polyketide or cross-bridging of the polyketide. Four rhamnose biosynthetic genes, two of which are also necessary for forosamine biosynthesis, are located outside the spinosyn gene cluster. Duplication of the spinosyn genes linked to the polyketide synthase genes stimulated the final step in the biosynthesis--the conversion of the forosamine-less pseudoaglycones to endproducts. Duplication of genes involved in the early steps of deoxysugar biosynthesis increased spinosyn yield significantly.
Metabolomic profile of diet-induced obesity mice in response to humanin and small humanin-like peptide 2 treatment (2019)

The present study indicates that humanin and SHLP2 can lower several markers associated with age-related metabolic disorders. With the previous understanding of the effects of humanin and SHLP2 on cardiovascular function, insulin sensitization, and anti-inflammation, this metabolomic discovery provides a more comprehensive molecular explanation of the mechanism of action for humanin and SHLP2 treatment.
Identification of steroid C27 monooxygenase isoenzymes involved in sterol catabolism and stepwise pathway engineering of <i>Mycobacterium neoaurum</i> for improved androst-1,4-diene-3,17-dione production (2019)

Cholesterol oxidase, steroid C27 monooxygenase and 3-ketosteroid-Δ<sup>1</sup>-dehydrogenase are key enzymes involved in microbial catabolism of sterols. Here, three isoenzymes of steroid C27 monooxygenase were firstly characterized from Mycobacterium neoaurum as the key enzyme in sterol C27-hydroxylation. Among these three isoenzymes, steroid C27 monooxygenase 2 exhibits the strongest function in sterol catabolism. To improve androst-1,4-diene-3,17-dione production, cholesterol oxidase, steroid C27 monooxygenase 2 and 3-ketosteroid-Δ<sup>1</sup>-dehydrogenase were coexpressed to strengthen the metabolic flux to androst-1,4-diene-3,17-dione, and 3-ketosteroid 9α-hydroxylase, which catalyzes the androst-1,4-diene-3,17-dione catabolism, was disrupted to block the androst-1,4-diene-3,17-dione degradation pathway in M. neoaurum JC-12. Finally, the recombinant strain JC-12<sub>S2-choM-ksdd/ΔkshA</sub> produced 20.1 g/L androst-1,4-diene-3,17-dione, which is the highest reported production with sterols as substrate. Therefore, this work is hopes to pave the way for efficient androst-1,4-diene-3,17-dione production through metabolic engineering.
Gain and loss as a function of current density and temperature in interband cascade lasers (2015)

We characterize the internal efficiency, internal loss, and optical gain versus current density in 7-stage interband cascade lasers operating at λ=3.1 and 3.45 μm using a cavity-length study of the external differential quantum efficiency (EDQE) and threshold current density at temperatures between 300 and 345 K. We find that the pronounced efficiency droop of the EDQE at high current densities is primarily due to an increase in the internal loss rather than a reduction in the internal efficiency. On the other hand, if the current density J is fixed, the temperature variation of the EDQE at that J is due primarily to a decrease of the internal efficiency. The gain versus current density is fit well by a logarithmic relationship, although the magnitude of the experimental gain is >20% below the theoretical estimate.
An ion-implanted silicon single-electron transistor (2005)

We report on the fabrication and electrical characterization at millikelvin temperatures of a novel silicon single-electron transistor (Si-SET). The island and source-drain leads of the Si-SET are formed by the implantation of phosphorus ions to a density above the metal-insulator-transition, with the tunnel junctions created by undoped regions. Surface gates above each of the tunnel junctions independently control the tunnel coupling between the Si-SET island and leads. The device shows periodic Coulomb blockade with a charging energy e$^2$/2C$_Σ$ $\sim$ 250 $μ$eV, and demonstrates a reproducible and controllable pathway to a silicon-based SET using CMOS processing techniques.
Actinic detection of EUVL mask blank defects (1998)

We report the design and initial experimental results of an actinic inspection system for extreme ultraviolet lithography mask blank defect detection. Initial bright-field and dark- field results demonstrate sensitivity to submicron size phase defects.
Asymmetric Scanner Design for Interventional Scenarios in Magnetic Particle Imaging (2015)

Magnetic particle imaging is an imaging modality that acquires quantitative information about the spatial distribution of magnetic nanoparticles. In combination with an excellent spatial and temporal resolution and due to the fact that no harmful radiation is used, the imaging technique offers possibilities with respect to medical application. As such, interventional scenarios, where it is mandatory to visualize the used instruments, are a perfectly suitable area of application. This paper describes the results of a feasibility study where a novel single-sided coil arrangement based on approximated elliptical coils is designed to be integrated into a patient table. Using such coils perfectly matches the requirements of good patient access, large field of view (FOV), and available space in the table. A small change in the aspect ratio leads to an enlarged FOV with sufficient gradient strength in all directions.
Metamaterial based devices for terahertz imaging (2010)

The terahertz (THz) region has been shown to have considerable application potential for spectroscopic imaging, nondestructive imaging through nonpolar, nonmetallic materials and imaging of biological materials. These applications have all been possible due to the recent progress in THz sources, detectors and measurement techniques. However, only moderate progress has been made in developing passive and active devices to control and manipulate THz radiation, which can enhance current imaging capabilities. One promising approach for implementing passive and active devices at THz frequencies are metamaterials - composite materials designed to have specific electromagnetic properties not found in naturally occurring materials. The most common implementation utilizes a metallic resonant particle periodically distributed in an insulator matrix where the periodicity is significantly smaller than the wavelength of operation. We have designed and implemented three metamaterial based devices with potential applications to THz imaging. We present an electrically-driven active metamaterial which operates as an external modulator for a ~2.8 THz CW quantum cascade laser. We obtained a modulation depth of ~60%. We also demonstrate a polarization sensitive metamaterial which can be used as a continuously variable attenuator or as a wave plate. The latter may be useful for the development of THz phase contrast imaging.
Ultrasonic Inspection to Quantify Failure Pathologies of Crimped Electrical Connections (2014)

Previous work has shown that ultrasonic inspection provides a means of assessing electrical crimp quality that ensures the electrical and mechanical integrity of an initial crimp before the installation process is completed. The amplitude change of a compressional ultrasonic wave propagating at right angles to the wire axis and through the junction of a crimp termination was shown to correlate with the results of destructive pull tests, which is a standard for assessing crimp wire junction quality. Of additional concern are crimps made at high speed assembly lines for wiring harnesses, which are used for critical applications, such as in aircraft. During high-speed assembly it is possible that many faulty crimps go undetected until long after assembly, and fail in service. The position and speed of the crimping jaw become factors as the high-speed crimp is formed. The work presented in this paper is designed to cover the more difficult and more subtle area of high-speed crimps by taking into account the rate change of the measurements. Building on the previous work, we present an analysis methodology, based on transmitted ultrasonic energy and timing of the first received pulse that is shown to correlate to the gauge of the crimp/ferrule combination and the position of the crimping jaw. Results demonstrating the detectability of a number of the crimp failure pathologies, such as missing strands, partially inserted wires and incomplete crimp compression, are presented. The ability of this technique to estimate crimp height, a mechanical measure of crimp quality, is discussed.
Low-Frequency Electromagnetic Imaging Using Sensitivity Functions and Beamforming (2020)

Related DatabasesWeb of Science You must be logged in with an active subscription to view this.Article DataHistorySubmitted: 7 August 2019Accepted: 13 February 2020Published online: 05 May 2020Keywordsimaging, Maxwell's equations, low frequency, VLF/ELF, computational imagingAMS Subject Headings78-04, 65R32, 35H99, 65T50Publication DataISSN (online): 1936-4954Publisher: Society for Industrial and Applied MathematicsCODEN: sjisbi
Li.sub.2 O-Al.sub.2 O.sub.3 -SiO.sub.2 glass ceramic-aluminum containing austenitic stainless steel composite body and a method of producing the same (1990)

The present invention relates to a hermetically sealed Li.sub.2 O-Al.sub.2 O.sub.3 -SiO.sub.2 glass ceramic-aluminum containing stainless steel composite body and a method of producing the body. The composite body includes an oxide interfacial region between the glass ceramic and metal, wherein the interfacial region consists essentially of an Al.sub.2 O.sub.3 layer. The interfacial Al.sub.2 O.sub.3 region includes constituents of both the metal and glass ceramic.
Antagonistic Anti-urokinase Plasminogen Activator Receptor (uPAR) Antibodies Significantly Inhibit uPAR-mediated (2010)

Interactionsbetweenurokinaseplasminogenactivatorreceptor(uPAR) and its various ligands regulate tumor growth, invasion,and metastasis. Antibodies that bind specific uPAR epitopesmay disrupt these interactions, thereby inhibiting these pro-cesses. Using a highly diverse and naive human fragment of theantigen binding (Fab) phage display library, we identified 12unique human Fabs that bind uPAR. Two of these antibodiescompete against urokinase plasminogen activator (uPA) foruPAR binding, whereas a third competes with 1 integrins foruPAR binding. These competitive antibodies inhibit uPAR-de-pendent cell signaling and invasion in the non-small cell lungcancer cell line, H1299. Additionally, the integrin-blockingantibody abrogates uPAR/ 1 integrin-mediated H1299 celladhesion to fibronectin and vitronectin. This antibody and oneof the uPAR/uPA antagonist antibodies shows a significantcombined effect in inhibiting cell invasion through Matrigel/CollagenIorCollagenImatrices.Ourresultsindicatethattheseantagonistic antibodies have potential for the detection andtreatment of uPAR-expressing tumors.
Synchronous DC link voltage control for microinverters with minimum DC link capacitance (2017)

This paper investigates DC link capacitor optimization for three-phase photovoltaic (PV) based microinverters. This concept minimizes the storage capacitance by allowing greater voltage ripple on the DC link. Therefore, the microinverter reliability can be significantly increased by replacing electrolytic capacitors with film capacitors. However, this intentionally increased voltage ripple can introduce harmonic distortion on the output current of the inverter stage if it is not mitigated by the DC link voltage controller. For this purpose, a robust and accurate DC link voltage control is proposed to filter this ripple while regulating the DC link voltage without using any additional circuit components. The experimental results on a 400-W three-phase half-bridge microinverter prototype validate the theoretical analysis of the DC link capacitor optimization and show that a significant reduction of the DC link capacitor requirement can be achieved. The proposed high accuracy DC link voltage controller is also implemented on this prototype to demonstrate very low harmonic distortion of the inverter output current while tightly regulating the DC link voltage even during transients.
An automated airway segmentation algorithm for CT images using topological leakage detection and volume freezing (2018)

Numerous multi-center studies related to chronic obstructive pulmonary disease use computed tomography (CT) based characterization of the lung parenchyma and bronchial tree to understand the disease's status and progression. To our knowledge, there are no fully automated methods for airway tree segmentation that don't require post-segmentation manual revision and intervention. In this paper, we present a novel CT-based airway tree segmentation algorithm using topological leakage detection and volume freezing. The method is fully automated requiring no manual inputs or post-segmentation editing. It uses intensity-based connectivity and novel approaches of leakage detection and volume freezing to iteratively grow an airway tree starting from an initial seed inside the trachea. It begins with a conservative threshold and then, iteratively shifts toward generous threshold values. The method was applied on chest CT scans of ten non-smoking healthy subjects at total lung capacity, and the results were highly promising with no visual segmentation leakages.
Spermicidal Activity of Metallocene Complexes Containing Vanadium(IV) in Humans1 (1998)

We have used computer-assisted sperm analysis (CASA) to evaluate the spermicidal activity of 8 metallocene dihalides (vanadocene dichloride [VDC], titanocene dichloride [TDC], zirconocene dichloride [ZDC], molybdocene dichloride [MDC], hafnocene dichloride [HDC], vanadocene dibromide [VDB], bis[methylcyclopentadienyl] vanadium dichloride [VMDC], and vanadocene diiodide [VDI]); 5 vanadocene di-pseudohalides (vanadocene diazide [VDA], vanadocene dicyanide [VDCN], vanadocene dioxycyanate [VDOCN], vanadocene dithiocyanate [VDSCN], and vanadocene diselenocyanate [VDSeCN]); and 3 disubstituted derivatives (vanadocene ditriflate [VDT], vanadocene monochloro oxycyanate [VDCO], and vanadocene monochloro acetonitrilo tetrachloro ferrate [VDFe]). Whereas the metallocene complexes containing titanium, zirconium, molybdenum, and hafnodium were inactive, all 12 vanadocene complexes elicited potent spermicidal activity at nano-micromolar concentrations with an order of efficacy VDSeCN > VDSCN > VDB > VMDC > VDCN > VDA > VDC > VDOCN > VDI > VDT > VDFe > VDCO without disrupting the acrosomal membrane, as determined by high-resolution low-voltage scanning electron microscopy. The sperm-immobilizing activity of the vanadocene complexes was rapid and irreversible, since the treated sperm underwent apoptosis as determined by the flow cytometric annexin V binding assay, DNA nick end-labeling, and confocal laser scanning microscopy. These results provide unprecedented evidence that metallocene complexes containing vanadium(IV), especially VDSeCN, may be useful as contraceptive agents.
Projection-based Bolus Detection for Computed Tomographic Angiography (2006)

Computed tomographic (CT) angiography is important for imaging studies on cardiovascular structures, peripheral vessels, and solid organs. In practice, a CT angiography scan is triggered by the bolus arrival at a prespecified anatomical location, which is determined using CT fluoroscopy. In this article, we propose a projection-based method adapted from the Grangeat formula to detect the bolus arrival. Then, we evaluate our new method in numerical and animal studies. Our results indicate that this method allows significantly better temporal resolution and is computationally more efficient, as compared with the image-based methods.
Advancing Prevention of STIs by Developing Specific Serodiagnostic Targets: Trichomonas vginalis as a Model (2020)

Point-of-Care (POC) serum antibody screening of large cohorts of women and men at risk for the sexually transmitted infection (STI) caused by <i>Trichomonas vaginalis</i> requires the availability of targets with high specificity. Such targets should comprise epitopes unique to <i>T. vaginalis</i> immunogenic proteins detected by sera of women and men patients with trichomonosis but not uninfected controls. Three enzymes to which patients make serum IgG antibody were identified as fructose-1,6-bisphosphate aldolase (A), α-enolase (E), and glyceraldehyde-3-phosphate dehydrogenase (G). Epitopes within these proteins were identified that had no sequence identity to enzymes of humans and other pathogens. Therefore, I constructed a chimeric recombinant String-Of-Epitopes (SOE) protein consisting of 15-mer peptides, within which are the epitopes of A, E, and G. This novel protein of ~36-kD is comprised of two epitopes of A, ten epitopes of E, and seven epitopes of G (AEG::SOE2). The AEG::SOE2 protein was detected both by immunoblot and by enzyme-linked immunosorbent assay (ELISA) using highly reactive sera of women and men but not negative serum unreactive to <i>T. vaginalis</i> proteins. Finally, AEG::SOE2 was found to be immunogenic, as evidenced by serum IgG from immunized mice. I discuss how this approach is important in relation to infectious disease diagnostic targets for detection of serum IgG antibody in exposed and/or infected individuals and how such novel targets may have potential as subunit vaccine candidates against microbial pathogens.
Exploiting multi-cycle false paths in the performance optimization of sequential circuits (1992)

A methodology for the redesign of sequential VLSI circuits to increase the circuit speed involves cascading the circuit over a plurality of time frames without the memory elements, identifying any long false paths in the cascaded circuit, reconfiguring the original circuit to eliminate the false paths while providing fanout to preserve functionality, and retiming the reconfigured circuit to reduce circuit delay.
Integration Options and Economic Analysis of an Integrated Chemical Looping Air Separation Process for Oxy-fuel Combustion (2015)

This paper is concerned about a detailed techno-economic assessment of a hypothetical 500 MWe coal-fired power plant in New South Wales, Australia, for oxy-fuel conversion using integrated chemical looping air separation (ICLAS) technology and cryogenic air separation unit (CASU). The key objectives of this study are to (i) investigate and compare the detailed integration options for oxy-fuel conversion using ICLAS and CASU and (ii) determine the technical merits of the above integration options and the conditions at which the technologies become economically feasible. The study produced scientific evidence that confirms the viability of the CLAS process from both technical and economic points of view under certain conditions. The detailed technical analysis revealed that ICLAS with natural gas integration is energy-efficient compared to CASU running on parasitic load. This is primarily due to the fact that ICLAS needs less auxiliary power compared to CASU. Despite the fact that ICLAS natural gas integration has resulted in higher efficiencies than CASU running on parasitic load, from a series of detailed economic analyses, it was observed that both ICLAS and CASU may not be viable under the present operating and economic conditions. Nevertheless, from sensitivity analysis, it was concluded that ICLAS can become feasible if economic conditions are improved, e.g., a low natural gas market price (<$3.5/GJ), a high electricity wholesale price (>$59/MWh), and/or a high carbon tax (>$33/tonne).