gebhart/patrepeval huggingface dataset:
Anisotropy Field Change by Annealing in He<sup>+</sup>/Ne<sup>+</sup>Ion-Implanted Bubble Garnet Films (1985)

Bubble garnet films, (YSmLuGd) <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> (FeGa) <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">5</sub> O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">12</sub> , were implanted with He, N, and Ne ions at 100-200 keV and annealed at 350 to 600°C, and changes in the maximum lattice strain, (Δa/a) <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">max</sub> , and in the effective anisotropy field, Δ(H <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">k</sub> -4πM <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">s</sub> ), were measured by double-crystal X-ray diffraction and ferromagnetic resonance. Lattice strain in layers implanted with He, N, and Ne ions decreased monotonically with annealing. The change in anisotropy field initially increases with heat treatment for samples implanted with heavy ion doses, then decreases. This increase was attributed to changes in the saturation magnetization M <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">s</sub> and magnetostriction coefficient λ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">111</sub> .
Synthesis of wideband speech from narrow-band speech based on piecewise linear mapping (1996)

On the analog telephone and the mobile telephone system, the bandwidth of the speech is limited from 300 Hz to 3.4 kHz. This paper proposes a new recovery method of wideband speech (50 Hz–7.4 kHz) from narrow-band speech based on piecewise linear mapping. In this method, first, the narrow-band spectrum envelope of input speech is transformed to a wideband spectrum envelope using linearly transformed matrices which are associated with several spectral spaces. These matrices were estimated by speech training data, so as to minimize the mean-square error between the transformed and the original spectra. Second, the residual wave with a wideband spectrum is generated from the residual wave of input speech by the nonlinear computation. Finally, the reconstructed wideband speech is synthesized from the transformed spectrum envelope and the generated residual wave. This algorithm is compared to the following other methods: (1) the codebook mapping [Y. Yoshida and M. Abe, Proc. of ICSLP94, 1591–1594 (1994)]; and (2) the neural network. Through the evaluation by the spectral distance measure, it was found that the proposed method achieved a 0.67-dB maximum lower spectral distortion than the other methods. Perceptual experiments indicate a good performance for the reconstructed wideband speech.
Drilling Performance Is a Function of Power at the Bit and Drilling Efficiency (2012)

This article is a condensed version of paper IADC/SPE 151389, presented at the 2012 International Association of Drilling Contractors (IADC)/SPE Drilling Conference and Exhibition, held in San Diego, California, USA, 6-8 March 2012. Understanding of basic drilling mechanics has been greatly enhanced by the use of today’s sophisticated data acquisition systems for both surface and downhole drilling data. These systems have also helped in identifying major dysfunctions—particularly, harmful downhole vibrations. Various methods are used to optimize drilling practices, including monitoring efficiency indicators, such as mechanical specific energy (MSE), as well as preventing harmful vibrations by adjusting drilling parameters real time. However, focusing on the efficiency of components and the prevention of dysfunctions is only a partial solution. It is also necessary to focus on the magnitude of mechanical power delivered to the bit, as that defines the capacity of the system and directly affects efficiencies, operating practices, and performance. The paper shows how the power at the bit and drilling efficiency vary as a function of drillstring and bottomhole assembly (BHA) configuration, bit selection, and drilling parameter. Field examples illustrate the magnitude of parasitic losses caused by well geometry and the downhole environment. In many cases it is striking to learn how little power is left for the drill bit, which in the end dictates the potential rate of penetration (ROP) and thus the cost per foot and economics of the drilling process. Particular emphasis has been put on new and intuitive ways to visually display the power at the surface and downhole. These make it possible to quantify system limits and identify key dysfunctions in one simple graph that can be used in real time as well as in both pre- or post-well analysis. Better understanding of the entire drilling system and the functional relationship of its parts can be a strong driver for both short- and long-term improvements in system design, drilling practices, and bit selection, ultimately resulting in higher productivity and lower well construction cost. Introduction The oil and gas industry, unlike others, seldom focuses on power requirements for the rotating drilling system and their effect on performance and efficiency. This might be explained in part by the fact that for about 100 years roller cone bits have been the industry’s preferred drilling tool. Roller cone bits require relatively little torque due to their low aggressiveness, and, due to the limited load capacity of the bearings, they act as perfect torque limiters. The rotating power system therefore utilized only a small fraction of the total installed power of a rotary drill rig; lack of power was not considered a limiting factor.
Novel <i>N</i>-transfer reagent for converting α-amino acid derivatives to α-diazo compounds (2021)

A novel universal N-transfer reagent for direct and effective transformation of α-amino ketones, acetamides, and esters to the corresponding α-diazo products under mild basic conditions has been developed. This one-step synthetic approach not only allows for generation of α-substituted-α-diazo carbonyl compounds from α-amino acid derivatives but also permits preparation of α-diazo dipeptides from N-terminal dipeptides (32 examples, up to 91%).
Prevention of air pollution by sulfur plants (1971)

Proteomics has played an important role in elucidating the fundamental processes occuring in living cells. Translating these methods to metallodrug research ('metalloproteomics') has provided a means for molecular target identification of metal-based anticancer agents which should signifcantly advance the research field. In combination with biological assays, these techniques have enabled the mechanisms of action of metallodrugs to be linked to their interactions with molecular targets and aid understanding of their biological properties. Such investigations have profoundly increased our knowledge of the complex and dynamic nature of metallodrug-biomolecule interactions and have provided, at least for some compound types, a more detailed picture on their specific protein-binding patterns. This perspective highlights the progression of metallodrug proteomics research for the identification of non-DNA targets from standard analytical techniques to powerful metallodrug pull-down methods.
Irrational Halftoning for Electronic Registration (2001)

As xerography moves to intercept offset printing, image quality becomes a key ingredient of success. Classic halftoning methods, which generally deliver good, low noise halftone dots, have fixed positions in the scan field that hinder several possible improvements to these printing systems.First, exact halftone frequencies and angles would result if dot positions could be adjusted with arbitrary precision. This would improve the design of screen-sets that limit or reduce multiseparation moiré, or allow screen-sets that exhibit the classic rosette structure associated with offset printing.Second, electronic registration systems could emerge if the halftone dot positions could be adjusted in response to actuation commands from the printer. Such systems would automatically compensate for mechanical distortions caused by bent mirrors, elliptical rollers, and tandem color print stations, for instance, and thus save manufacturing costs for the mechanical system.Normally, the dot positions are fixed to small integer offsets (the angle corresponds to a “rational tangent”) in the scan field, thus preventing the occurrence of single separation moiré. When fractional dot positions are allowed (irrational tangent), moiré can result. Thus, if the moiré problem can be eliminated for irrational halftoning, the frequency and angle restrictions associated with rational tangent halftoning disappear.I will present one solution to this problem that subsamples a halftone cluster function stored in a look-up table to produce reduced moiré separations while printing. Halftone dot locations are computed by hardware, and dot cluster shapes typically do not repeat. I will show a simulation of a three-separation image printed on a 600 spi digital printer that uses irrational offsets (m30°, c75°, and k45°) designed to produce a classic rosette structure. I will also show a simulation of these same dots being electronically registered, or warped.
Molecular cloning and sequence analysis of Newcastle disease virus (1986)

Conference Article| February 01 1986 Molecular cloning and sequence analysis of Newcastle disease virus PHILIP CHAMBERS; PHILIP CHAMBERS *Department of Biochemistry, University of Newcastle upon Tyne, Newcastle upon Tyne, NE1 7RU, U.K. Search for other works by this author on: This Site PubMed Google Scholar NEIL S. MILLAR; NEIL S. MILLAR *Department of Biochemistry, University of Newcastle upon Tyne, Newcastle upon Tyne, NE1 7RU, U.K. Search for other works by this author on: This Site PubMed Google Scholar PETER T. EMMERSON; PETER T. EMMERSON † *Department of Biochemistry, University of Newcastle upon Tyne, Newcastle upon Tyne, NE1 7RU, U.K. †To whom correspondence should be addressed Search for other works by this author on: This Site PubMed Google Scholar RICHARD W. BINGHAM RICHARD W. BINGHAM ‡Department of Biochemistry, University of Newcastle upon Tyne Royal (Dick) Veterinary School, University of Edinburgh, Edinburgh, EH9 1QH, U.K. Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1986) 14 (1): 100–101. https://doi.org/10.1042/bst0140100 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Citation PHILIP CHAMBERS, NEIL S. MILLAR, PETER T. EMMERSON, RICHARD W. BINGHAM; Molecular cloning and sequence analysis of Newcastle disease virus. Biochem Soc Trans 1 February 1986; 14 (1): 100–101. doi: https://doi.org/10.1042/bst0140100 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search Keywords: NDV, Newcastle disease virus, HN, haemagglutinin-neuraminidase, F, fusion protein This content is only available as a PDF. © 1986 Biochemical Society1986 Article PDF first page preview Close Modal You do not currently have access to this content.
Asynchronous assertions (2011)

Assertions are a familiar and widely used bug detection technique. Traditional assertion checking, however, is performed synchronously, imposing its full cost on the runtime of the program. As a result, many useful kinds of checks, such as data structure invariants and heap analyses, are impractical because they lead to extreme slowdowns. We present a solution that decouples assertion evaluation from program execution: assertions are checked asynchronously by separate checking threads while the program continues to execute. Our technique guarantees that asynchronous evaluation always produces the same result as synchronous evaluation, even if the program concurrently modifies the program state. The checking threads evaluate each assertion on a consistent snapshot of the program state as it existed at the moment the assertion started. We implemented our technique in a system called Strobe, which supports asynchronous assertion checking in both single-and multi-threaded Java applications. Strobe runs inside the Java virtual machine and uses copy-on-write to construct snapshots incrementally, on-the-fly. Our system includes all necessary synchronization to support multiple concurrent checking threads, and to prevent data races with the main program threads. We find that asynchronous checking significantly outperforms synchronous checking, incurring tolerable overheads -- in the range of 10% to 50% over no checking at all -- even for heavy-weight assertions that would otherwise result in crushing slowdowns.
Memory-constrained aggregate computation over data streams (2011)

In this paper, we study the problem of efficiently computing multiple aggregation queries over a data stream. In order to share computation, prior proposals have suggested instantiating certain intermediate aggregates which are then used to generate the final answers for input queries. In this work, we make a number of important contributions aimed at improving the execution and generation of query plans containing intermediate aggregates. These include: (1) a different hashing model, which has low eviction rates, and also allows us to accurately estimate the number of evictions, (2) a comprehensive query execution cost model based on these estimates, (3) an efficient greedy heuristic for constructing good low-cost query plans, (4) provably near-optimal and optimal algorithms for allocating the available memory to aggregates in the query plan when the input data distribution is Zipf-like and Uniform, respectively, and (5) a detailed performance study with real-life IP flow data sets, which show that our multiple aggregates computation techniques consistently outperform the best-known approach.
A Novel Fiber Optic System for Measuring the Dynamic Structural Behavior of Parachutes (2000)

A novel approach has been developed for real-time characterization of a parachute during inflation. Two techniques were applied to measure static and dynamic stresses in a parachute canopy fabric material and suspension lines: the modal power distribution (MPD) technique and the fiber Bragg grating (FBG) technique. Several tests were conducted under various loading conditions, using a bi-axial tensile tester. The MPD technique was used to measure the transverse stresses in the parachute canopy fabric material and was applied using two experimental set-ups: one using a CCD camera and the other using a photo-detector. The FBG technique was used to measure the axial stresses in the parachute canopy fabric material. The tests were performed using the spectrum analyzer set-up with the bi-axial machine. Finally, a drop test was performed on the parachute canopy fabric material using the MPD technique with the photo-detector set-up.
NEU1 Sialidase Regulates Membrane-tethered Mucin (MUC1) Ectodomain Adhesiveness for Pseudomonas aeruginosa and Decoy Receptor Release (2015)

Airway epithelia express sialylated receptors that recognize exogenous danger signals. Regulation of receptor responsiveness to these signals remains incompletely defined. Here, we explore the mechanisms through which the human sialidase, neuraminidase-1 (NEU1), promotes the interaction between the sialoprotein, mucin 1 (MUC1), and the opportunistic pathogen, Pseudomonas aeruginosa. P. aeruginosa flagellin engaged the MUC1 ectodomain (ED), increasing NEU1 association with MUC1. The flagellin stimulus increased the association of MUC1-ED with both NEU1 and its chaperone/transport protein, protective protein/cathepsin A. Scatchard analysis demonstrated NEU1-dependent increased binding affinity of flagellin to MUC1-expressing epithelia. NEU1-driven MUC1-ED desialylation rapidly increased P. aeruginosa adhesion to and invasion of the airway epithelium. MUC1-ED desialylation also increased its shedding, and the shed MUC1-ED competitively blocked P. aeruginosa adhesion to cell-associated MUC1-ED. Levels of desialylated MUC1-ED were elevated in the bronchoalveolar lavage fluid of mechanically ventilated patients with P. aeruginosa airway colonization. Preincubation of P. aeruginosa with these same ex vivo fluids competitively inhibited bacterial adhesion to airway epithelia, and MUC1-ED immunodepletion completely abrogated their inhibitory activity. These data indicate that a prokaryote, P. aeruginosa, in a ligand-specific manner, mobilizes eukaryotic NEU1 to enhance bacterial pathogenicity, but the host retaliates by releasing MUC1-ED into the airway lumen as a hyperadhesive decoy receptor.
Modulation of insulin-like growth factor-1 receptor and its signaling network for the treatment of cancer: current status and future perspectives (2013)

Based on over three decades of pre-clinical data, insulin-like growth factor-1 receptor (IGF-1R) signaling has gained recognition as a promoter of tumorogenesis, driving cell survival and proliferation in multiple human cancers. As a result, IGF-1R has been pursued as a target for cancer treatment. Early pioneering efforts targeting IGF-1R focused on highly selective monoclonal antibodies, with multiple agents advancing to clinical trials. However, despite some initial promising results, recent clinical disclosures have been less encouraging. Moreover, recent studies have revealed that IGF-1R participates in a dynamic and complex signaling network, interacting with additional targets and pathways thereof through various crosstalk and compensatory signaling mechanisms. Such mechanisms of bypass signaling help to shed some light on the decreased effectiveness of selective IGF-1R targeted therapies (e.g. monoclonal antibodies) and suggest that targeting multiple nodes within this signaling network might be necessary to produce a more effective therapeutic response. Additionally, such findings have led to the development of small molecule IGF-1R inhibitors which also co-inhibit additional targets such as insulin receptor and epidermal growth factor receptor. Such findings have helped to guide the design rationale of numerous drug combinations that are currently being evaluated in clinical trials.
Heterogeneity of motilin immunoreactivity in mammalian tissue (1988)

Motilin is a 22 amino acid peptide first isolated and sequenced from porcine gut. The use of antisera directed to the synthetic porcine gut motilin sequence has produced conflicting results as to regional distribution and histological localization of motilin in mammalian brain and gut. Motilin immunoreactivity has been detected (by RIA) in brain regions where no immunostaining is discernible. Variations in the patterns of staining are also observed with different antisera. These discrepancies have been explained by postulating species-, tissue-, and region-specific variations in peptide immunoreactivity, and variable cross reactivities of the independent antisera with these forms. The use of cloned porcine cDNA encoding gut prepromotilin in Northern blot analysis of brain regions expressing motilin-like immunoreactivity has also failed to reveal a homologous message, questioning the true nature of the immunoreactive material in the brain. Physiological studies, however, have suggested central roles for motilin in a variety of CNS (feeding behavior, bladder control, cerebral and brain stem modulation, pituitary growth hormone release) and gastrointestinal (gastric emptying, intestinal motility) functions. The motilin immunoreactive material detected in brain may be encoded by a distinct non-homologous gene, and still share amino acid homologies with the motilin sequence. Molecular biological characterization of the cell systems which contain motilin and motilin-like immunoreactivity should allow a better definition of their roles in these tissues.
Generative Urban Design: Integrating Financial and Energy Goals for Automated Neighborhood Layout (2018)

This paper demonstrates an application of Generative Design to an urban scale through the design of a real-world residential neighborhood development project in Alkmaar, Netherlands. Problems in urban design can benefit greatly from the Generative Design framework due to their complexity and the presence of many stakeholders with various and potentially conflicting demands. We demonstrate this potential complexity by optimizing for two important goals: the profitability of the project for the developer and the potential for energy generation of solar panels placed on the roofs of the buildings. This paper points to further research into the application of the Generative Design framework to solve design problems at an urban scale.
THz-wave parametric oscillator with a surface-emitted configuration (2006)

We propose a surface-emitted cavity configuration for a terahertz-wave parametric oscillator that allows THz wave emission perpendicular to the crystal surface without any output coupler. The oscillating idler and pump waves are reflected at the surface of a nonlinear crystal in a single resonance cavity, satisfying the noncollinear phasematching condition. The radiated THz wave has a Gaussian profile. The measured beam quality factors (M(2)) were 1.15 and 1.25 in the horizontal and vertical directions, respectively. The measured tunable range was 0.8-2.74 THz. A test of transmission imaging using a test pattern was demonstrated.
Design and simulation of a novel klynac device for generation of bremsstrahlung radiation (2015)

Bremsstrahlung radiation is highly sought after for endless applications from medical and biological to military uses. Bremsstrahlung radiation is typically produced by nuclear reactors and linear accelerators, these sources are rarely practical due to their large sizes. A novel device is being designed and tested at LANL to meet the need for a compact bremsstrahlung radiation source. The klynac, a combined klystron - linac device, is designed to be a compact source that accelerates an electron beam from a klystron source to 1 MeV. The novel device consists of 8 cavities, the first four are coupled klystron cavities and the second four serve as accelerating cavities. This device operates at 2.856 GHz. The klystron section uses a resonant cavity circuit where the first three cavities are locked together. The fourth klystron cavity is locked to the following accelerator cavities to ensure frequency stability of the device. The electron beam from the klystron cavities is reduced in current by an iris that allows 10% of the beam to pass to the accelerating cavities. Design and optimization has been performed though PIC simulations. Direct experimental verification of the klynac concept is underway.