gebhart/patrepeval huggingface dataset:
Chromosome structure predicted by a polymer model (1998)

Human chromosomes were simulated by a polymer model in the presence of an excluded-volume interaction. The polymer chain of each chromosome was arranged into loops and several consecutive loops formed subcompartments. We observed the formation of distinct chromosome territories with separated chromosome arms and subcompartments in agreement with recent experiments. Mean spatial distances between markers agree with measurements under different preparation conditions. Different scaling properties were found depending on the genomic distance regarded. The radial density, the position of genes, and the overlap of chromosome arms and subcompartments agree with experimental results. The parallelization of the Monte Carlo and Brownian dynamics algorithms and a method for the computation of confocal images is described, which allows a direct comparison with results from confocal light microscopy.
A Meta-Analysis of Age of Onset and Disease Course in Autosomal Dominant Alzheimer's Disease Mutations (PD5.002) (2013)

OBJECTIVE: To develop evidence-based criteria for early prediction of disease onset in autosomal dominant Alzheimer's disease (ADAD).
[From cytogenetics to cytogenomics of bladder cancers]. (2002)

Bladder cancers are classified as: transitional cell carcinoma (TCC), the most frequent in Europe/USA, squamous cell carcinoma (SCC), more frequent in the Middle East and in Africa, adenocarcinoma and small cell carcinoma, rare. TCC exhibit pseudo diploid karyotypes with only a few anomalies in early stages, evolving towards pseudo-tetraploides complexes karyotypes. Partial or complete monosomy 9 (-9) is an early event, found in half cases. Deletion (11p) or -11 is found in 20-50% of cases, more often in high grade and invasive tumours. Del(13q) is found in 25% of cases and correlated with high grade/stage; tumours with Rb alterations are invasives. Del(17p) is a late event, found in 40% of cases; P53 alterations are correlated with grade and stage, tumour progression, and a worse prognosis. Del(1p), i(5q), +7, and many other rearrangements - more often deletions than duplications - are frequently found. These losses of heterozygocity point to a multistep complex process involving tumor suppressor genes. In SCC, monosomy 9 is also an early event, even more frequent than in TCC; homozygous deletion of P16 is frequent. Trisomy 7 seems to be more frequent than in TCC. Chromosome 17 is often implicated, especially in high grades/stages; the profile of mutations of P53 is different from what is found in TCC. Allelic losses of 3p, 8p, 9p, 9q, 17p are frequent. The karyotype is more complex in advanced grades/stages, as in TCC.
Learning as Displacement and Transformation (2013)

The interdependence of materiality and sensation carried out by corporal means creates the modes of a corporal self-perception. We call them modes of a self and world constituting corporality. In this paper a study is presented how different modes of a self and world constituting corporality can be empirically explored and theoretically unfolded. Our corporality is constitutive for our reference to the world(cp. Merleau-Ponty 1968, Waldenfels 2000, Meyer-Drawe 2008). We do not only perceive the objects that are given to us in our perceptions, we also relate ourselves to our environment by means of our body. It is been empirically demonstrated that children in their first year of life use their corporal faculty of expression in a communicative way to reach a certain aim (cf. Dornes 1993 and others). Up to late childhood, and after, human beings still appropriate (learn) objects primarily in a corporal way. Each of us interprets the world according to his/her individual way(s) of cultivation and mode of learning. The manifold activities of our bodies and corporality as a primary medium of learning can be considered only by understanding corporality not as a mere device but also as an agile and living body. Unlike the currently widespread differentiation between “having a body” and “being a body”, introduced by Helmuth Plessner (1982), the conception of corporality introduced by Maurice Merleau-Ponty (1968) provides shelter for the body as a substance on one hand and as a sensitive and vivid organism on the other hand. Transformation, displacement and the diverse ways of showing are esthetical processes in which the corporal aspects of learning become visible.
Network biology methods integrating biological data for translational science (2012)

The explosion of biomedical data, both on the genomic and proteomic side as well as clinical data, will require complex integration and analysis to provide new molecular variables to better understand the molecular basis of phenotype. Currently, much data exist in silos and is not analyzed in frameworks where all data are brought to bear in the development of biomarkers and novel functional targets. This is beginning to change. Network biology approaches, which emphasize the interactions between genes, proteins and metabolites provide a framework for data integration such that genome, proteome, metabolome and other -omics data can be jointly analyzed to understand and predict disease phenotypes. In this review, recent advances in network biology approaches and results are identified. A common theme is the potential for network analysis to provide multiplexed and functionally connected biomarkers for analyzing the molecular basis of disease, thus changing our approaches to analyzing and modeling genome- and proteome-wide data.
Management of the Rice Tungro Virus Vector Nephotettix virescens (Homoptera: Cicadellidae) with Controlled-Release Formulations of Carbofuran (1984)

Field trials were conducted in lowland flooded rice in the Philippines to evaluate a number of carbofuran controlled-release formulations in comparison with commercial formulations. The test formulations were based on a biodegradable matrix of pine kraft lignin and were used as granules of different sizes and also in the form of small strips. The release rates were assessed under field conditions by bioassaying rice plants in the field, using adult rice green leafhopper, Nephotettix virescens Distant. The lignin formulations with a high level of active ingredient (15–45% by weight) gave as good or better control than the commercial 3% granules in tests based on three application techniques: broadcast into the floodwater, soil incorporation, and root zone injection. The improvements in control levels of green leafhoppers were most marked with soil incorporation and root zone application. The best lignin-based formulation reduced levels of tungro virus infection from 23% for a conventional flowable carbofuran formulation to 1.0% at an application rate of 0.5 kg (AI)/ha. At the same rate, the grain yield was increased from 3.56 t/ha to 5.5 t/ha, using the controlled-released formulation.
Multiplication Acceleration Through Twin Precision (2009)

We present the twin-precision technique for integer multipliers. The twin-precision technique can reduce the power dissipation by adapting a multiplier to the bitwidth of the operands being computed. The technique also enables an increased computational throughput, by allowing several narrow-width operations to be computed in parallel. We describe how to apply the twin-precision technique also to signed multiplier schemes, such as Baugh-Wooley and modified-Booth multipliers. It is shown that the twin-precision delay penalty is small (5%-10%) and that a significant reduction in power dissipation (40%-70%) can be achieved, when operating on narrow-width operands. In an application case study, we show that by extending the multiplier of a general-purpose processor with the twin-precision scheme, the execution time of a Fast Fourier Transform is reduced with 15% at a 14% reduction in datapath energy dissipation. All our evaluations are based on layout-extracted data from multipliers implemented in 130-nm and 65-nm commercial process technologies.
Performance Study of a PET Detector Module Based on a Continuous Scintillator (2006)

Several methods are tested to extract positional information from light distributions generated in a monolithic block of scintillator read out by an APD array. The spatial resolution of photons impinging at 0deg and 20deg angle was studied in various regions of the block. The influence of the block thickness on the spatial resolution was also investigated as well as the effect of a black crystal coating. Finally the performances of detectors based on these continuous scintillator blocks are compared with a detector module based on an array of small scintillation crystals coupled individually to the pixels of the APD array
The Emission Gated Device Experiment (2002)

The Emission Gated Device Experiment has been constructed to observe a prebunched electron beam in a traveling wave circuit. The objective of this study is to define the efficiency, bandwidth, and high-frequency performance of emission gated devices for potential applications in radar, electronic warfare, and neutral particle beam accelerators. With tight bunches injected into an undriven helix one wavelength long, an efficiency of 6% and a gain of 10 dB have been observed. Experimental results and simulations are compared with a view to understanding the dynamics of the bunched beam in the circuit fields. Tight bunching and high average current are shown to be the strongest contributors to high efficiency; therefore, a practical device requires a very high gain input circuit.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Predictability of population displacement after the 2010 Haiti earthquake (2012)

Most severe disasters cause large population movements. These movements make it difficult for relief organizations to efficiently reach people in need. Understanding and predicting the locations of affected people during disasters is key to effective humanitarian relief operations and to long-term societal reconstruction. We collaborated with the largest mobile phone operator in Haiti (Digicel) and analyzed the movements of 1.9 million mobile phone users during the period from 42 d before, to 341 d after the devastating Haiti earthquake of January 12, 2010. Nineteen days after the earthquake, population movements had caused the population of the capital Port-au-Prince to decrease by an estimated 23%. Both the travel distances and size of people's movement trajectories grew after the earthquake. These findings, in combination with the disorder that was present after the disaster, suggest that people's movements would have become less predictable. Instead, the predictability of people's trajectories remained high and even increased slightly during the three-month period after the earthquake. Moreover, the destinations of people who left the capital during the first three weeks after the earthquake was highly correlated with their mobility patterns during normal times, and specifically with the locations in which people had significant social bonds. For the people who left Port-au-Prince, the duration of their stay outside the city, as well as the time for their return, all followed a skewed, fat-tailed distribution. The findings suggest that population movements during disasters may be significantly more predictable than previously thought.
Reconstruction of the Peroneus Brevis Tendon Tears with Semitendinosus Tendon Autograft (2019)

Peroneal tendon disorders are common causes of lateral and retromalleolar ankle pain. For irreparable tears of the tendon, a salvage procedure is indicated with segmental resection followed by reconstruction with tenodesis, tendon transfer, or bridging the defect using allograft or autograft. Although there is insufficient evidence to guide which of these treatment options provides the best outcomes, reconstruction with tendon allograft has provided satisfactory clinical results and is effective for pain relief and restoration of tendon function. However, there are concerns about the use of tendon allografts which include its cost and availability, disease transmission, delayed incorporation, and stretching of the graft. The aim of this study is to present the surgical technique for the reconstruction of the peroneus brevis tendon tears using semitendinosus tendon autograft as an alternative to the allograft and report the short-term results of three cases.
The Hinoki Treebank. Working Toward Text Understanding (2004)

In this paper we describe the construction of a new Japanese lexical resource: the Hinoki treebank. The treebank is built from dictionary definition sentences, and uses an HPSG based Japanese grammar to encode the syntactic and semantic information. We show how this treebank can be used to extract thesaurus information from definition sentences in a language-neutral way using minimal recursion semantics. 1
Location-based decision support for user groups (2009)

The ongoing progression of mobile communication devices, in particular with respect to positioning capabilities, has enabled the development of a new generation of location-based services (LBS). One of the most important aspects of current research on LBS is personalisation but it has been treated primarily for individual users. This article presents a first step towards personalised LBS that support user groups in their everyday decision-making, such as deciding where and when to meet for a common activity. The principles behind location-based group decision processes are outlined and a formal model for supporting such processes using methods of multi-criteria decision-making, time geography and similarity measurement is defined. This model is then implemented in the LBS prototype mediatrix. The prototype is used for simulating a location-based decision process aimed at finding an optimal restaurant for a user group in a city.
Lipid Accumulation Product and Hypertension Related to Stroke: a 9.2-Year Prospective Study Among Mongolians in China (2016)

The present study showed that high LAP was associated with an increased risk of future stroke, and hypertensives with high LAP had the highest risk of stroke among Inner Mongolians. These findings indicate that LAP and hypertension may be valuable to predict and prevent stroke incidence.
The effectiveness of music therapy for patients with cancer: A systematic review and meta‐analysis (2020)

Music therapy can improve the overall quality of life of patients with cancer, with an observed optimal intervention duration of 1-2 months. Meanwhile, anxiety, depression and pain are improved as well. Nevertheless, high-quality trials are still needed to further determine the effects of music intervention in supportive cancer care.
Propranolol during the evolution and subsequent ten days of myocardial infarction in man: Hemodynamic, initial cardiac energetic, and neurohumoral responses (1979)

Abstract During the evolution of transmural myocardial infarction an intensive sympathetic hyperactivity was observed. Plasma l ‐norepinephrine and epinephrine contents were strikingly increased, the mean values to 2.047±1.10 (SD) and 0.947±0.48 μg/l, respectively. Propranolol (0.1 mg/kg) was administered intravenously within an average of 8.8 h of transmural myocardial infarction to 55 patients who did not show significant left ventricular failure. The drug was continued orally with an average dose of 567±20 (SD) mg q6h for 10 d. Mean plasma propranolol levels during the first 5 d ranged between 89 and 162 ng/ml. Cardiac index, left ventricular ejection fraction, and, to a lesser degree, blood pressure significantly decreased. Mean pulmonary capillary wedge pressure remained unchanged. Decreases in coronary blood flow and myocardial oxygen consumption were associated with improvement of myocardial lactate metabolism, suggesting reduced myocardial oxygen requirements. Plasma free fatty acid contents significantly decreased. Myocardial glucose extraction and respiratory quotient increased, indicating enhanced carbohydrate utilization. Prior to propranolol administration, plasma glucose and glucagon contents were increased and plasma insulin levels were inappropriately low. Initial glucagon and initial l ‐norepinephrine and epinephrine contents were correlated (r = 0.54 and 0.50, p <0.01). Beta‐adrenergic blockade decreased plasma insulin contents in spite of hyperglycemia and abolished the correlation between glucagon and catecholamines. Propranolol was tolerated well by all patients; none of them developed acute left ventricular failure. The study demonstrates that propranolol can be safely administered during the evolution and early phase of transmural myocardial infarction, if selection criteria for patients are carefully considered. Propranolol, dampening the response to acute ischemic stress, diminishes energy requirements and thus appears to be a promising drug for preservation of ischemic myocardium.
Ceramic Fibers Based on SiC and SiCN Systems: Current Research, Development, and Commercial Status (2014)

Non‐oxide ceramic fibers are of considerable interest due to the ability to combine the high performance, especially high temperature thermal and creep resistance, with the structural advantages of fibers including their use as reinforcements for metal (MMCs) and ceramic matrix composites (CMCs). In this paper the development of CVD SiC fibers and three generations of polymer derived SiC fibers over the past 50 years are discussed, illustrating the effect of fiber precursor and processing on the microstructure and physical properties of the non‐oxide ceramic fibers. Additionally recent advances in research and development related to fibers from SiC and SiCN systems are presented with discussion of the current focus on reducing the costs of the fiber processing, while increasing their thermostructural stability.
The Fabrication of ZnO Microrods on Monolayer Graphene and Their Photocatalytic Application (2015)

Zinc oxide (ZnO) microrods were fabricated on graphene/SiO(2)/Si substrate by a simple hydrothermal route. The obtained products were characterized using X-ray powder diffraction, scanning electron microscopy, energy dispersive X-ray spectrometry, photoluminescence and UV-visible spectrometry. Microrods exhibits hexagonal wurzite structure. Some ZnO clusters and twinned ZnO structures were found spread on the microrod array layer. The formation mechanism of ZnO microrods is discussed, emphasizing the formation mechanism of isolated clusters and twinned ZnO structures. Furthermore, microrods demonstrated a good photocatalytic performance towards rhodamine B degradation as ascribed to oxygen vacancies and interstitials considered as the photocatalytical active sites.
Diurea Cross-Linked Poly(oxyethylene)/Siloxane Ormolytes for Lithium Batteries (2005)

Poly(oxyethylene) (POE)/siloxane hybrids (di-ureasils) doped with a wide concentration range of lithium triflate (LiCF3SO3) were investigated. The host matrix of these materials [d-U(2000)] is a sol-gel-derived siliceous framework to which POE chains with about 40.3 repeat units are bonded through urea linkages. Xerogels with ∞ ≥ n ≥ 5 (n is the molar ratio OCH2CH2/Li+) were obtained as amorphous monoliths thermally stable up to at least 340°C. A crystalline POE/LiCF3SO3 complex was detected spectroscopically in samples with n ≤ 10. Below 90°C the ormolyte with n = 20 exhibits the highest conductivity (5.8 × 10-6 n-l cm-1 at 26°C). The redox stability domain of this material spans 4.1 V. Although Fourier transform infrared spectroscopy data suggest that the Li+ ions are complexed by the POE ether oxygen atoms at n ≤10, this threshold composition is probably located at slightly lower salt content "Free" triflate ions and weakly coordinated anions, present in all the samples examined, must be the main charge carriers of the d-U(2000) 20LiCF3SO3 xerogel. Ion pairs (Li +CF3SO3-) or negatively charged triplets ([Li(CF3SO3)2]-) are formed at n ≤ 40. At n ≤ 5 positively charged triplets [Li2(CF 3SO3)]+ also appear. Divalent positively charged multiplets [Li3(CF3SO3)]2+ occur at n = 1.
Diffraction imaging – a tool to reduce exploration and development risk (2016)

When evaluating exploration prospects, discoveries or a field under development it is essential to build an accurate structural framework at an appropriate scale. Detailed understanding of the fault network enables reservoir compartmentalisation risk to be better quantified at the exploration prospect stage and informs well placement optimisation in the exploration, appraisal and development phase. This paper presents a method for maximising fault information from depth migrated narrow azimuth seismic data. The faults are imaged in the depth domain by separating the diffracted component from the total migrated wavefield. We show that diffraction imaging gives higher resolution fault definition than either a conventional seismic reflectivity volume or conventional post-stack fault enhancement attributes. We also show that diffraction volumes can be further processed to generate attribute volumes with fault definition sharp enough to pick with automatic fault detection algorithms, producing a highly-detailed fault network that can augment manual fault interpretation products and be incorporated into the structural framework. Diffraction imaging is a technique for imaging small scale subsurface geological objects and discontinuities, such as faults, unconformities and karsts using the diffracted component of the total recorded wavefield.
Correlation of Modified Allen Test with Doppler Ultrasonography (2006)

The feasibility of using modified Allen tests to evaluate arterial circulation in the forearm for possible radial artery grafting, and the correlation of these tests with Doppler ultrasonography, were examined. The hand circulation of 50 patients scheduled for coronary artery bypass grafting was assessed by plethysmography, pulse oximetry, and pencil Doppler, as well as Doppler ultrasonography. Flow, velocity, and diameter of the radial, ulnar, and snuffbox arteries were recorded, and radiological screening indices were evaluated to establish a standard set of criteria. The results of modified Allen tests by plethysmography and pulse oximetry demonstrated the dominance of the ulnar artery. The indices of flow x diameter and velocity x diameter, obtained from Doppler ultrasound measurements, confirmed the dominance of the ulnar artery. When compression was applied to the arteries sequentially, significant alterations were found. The arterial circulation in the forearm can be safely evaluated by the modified Allen tests with plethysmography, pulse oximetry, and pencil Doppler, as these results correlated with Doppler ultrasound.
Order Selection Of 2-D Ar Model Using A Lattice Representation And Information Criteria For Texture Analysis (2015)

Publication in the conference proceedings of EUSIPCO, Tampere, Finland, 2000
Venöse Sauerstoffsättigung (2009)

Die venöse Sauerstoffsättigung ist ein globaler Parameter zur Abschätzung der Balance zwischen Sauerstoffangebot und Sauerstoffbedarf. Aussagen zu regionalen Störungen der Sauerstoffbilanz sind mit der venösen Sauerstoffsättigung aber nicht zu treffen.