gebhart/patrepeval huggingface dataset:
EVALUATION OF GAMMA-GAMMA WELL LOGGING DATA APPLIED TO IRON ORE EXPLORATION – VALE GEOPHYSICAL WELL LOGGING TEST FACILITY (2016)

ABSTRACT. The present paper shows the results of density measurement tests determined by probing of gamma-gamma geophysical well logging, performed in two stages: one at VALE Geophysical Well Logging Test Facility (GWTF), and another in boreholes for iron ore exploration...Keywords: geophysical well logging, iron ore exploration, data evaluation. RESUMO. O presente trabalho mostra os resultados dos testes de aferição de valores de densidades determinados por sonda de perfilagem geofísica gama-gama, realizados em duas etapas, uma no Campo de Teste de Perfilagem Geofísica VALE e outra em furos de sondagem para exploração de minério de ferro.Palavras-chave: perfilagem geofísica, exploração mineral de ferrosos, aferição de dados.
<title>Thiophene-based conducting polymer molecular actuators</title> (2002)

Traditional conducting polymer actuators such as polypyrrole offer tremendous active stress at low actuation voltages but with moderate strain, strain-rate and efficiency. We report the synthesis of novel thiophene based conducting polymer molecular actuators, exhibiting electrically triggered molecular conformational transitions. In this new class of materials, actuation is the result of conformational rearrangement of the polymer backbone at the molecular level and is not simply due to ion intercalation in the bulk polymer chain upon electrochemical activation. Molecular actuation mechanisms results from (pi) $min(pi) stacking of thiophene oligomers upon oxidation, producing a reversible molecular displacement which is expected to lead to surprising material properties such as electrically controllable porosity and large strains. The hypothesis of active molecular conformational changes is supported by in situ electrochemical data. Single molecule techniques are considered for molecular actuator characterization. Mechanical properties of these new materials are currently being assessed.
At-wavelength, system-level flare characterization of extreme-ultraviolet optical systems (2000)

The extreme-ultraviolet (EUV) phase-shifting point-diffraction interferometer (PS/PDI) has recently been developed to provide high-accuracy wave-front characterization critical to the development of EUV lithography systems. Here we describe an enhanced implementation of the PS/PDI that significantly extends its measurement bandwidth. The enhanced PS/PDI is capable of simultaneously characterizing both wave front and flare. PS/PDI-based flare characterization of two recently fabricated EUV 10x-reduction lithographic optical systems is presented.
Eradication of experimental brain metastases of human non-small cell lung cancer by macitentan, a dual antagonist of the endothelin A and B receptor, combined with paclitaxel. (2012)

92 Background: Treatment of patients with lung cancer brain metastases remains a major challenge because of the limited availability of standard therapy. Thus, the development of successful treatment options for these patients is mandatory. Recently, the endothelin axis was reported to be involved in cancer progression through its pleiotropic biological effects on cell survival, proliferation, invasion, and metastasis. Methods: In this study, we evaluated both the in vitro and in vivoeffects of macitentan, an orally bioavailable, dual endothelin A receptor and endothelin B receptor antagonist, as monotherapy, and in combination with paclitaxel. Results: In human non-small cell lung cancer PC-14 cells, macitentan treatment inhibited cell proliferation, corresponding with inhibition of Akt and p42/44 mitogen-activated protein kinase phosphorylation, and increased apoptosis. The combination of macitentan and paclitaxel resulted in the potentiation of all of these effects, suggesting that macitentan could enhance sensitivity to paclitaxel. Moreover, macitentan completely abrogated astrocyte-mediated protection of tumor cells against paclitaxel. In an experimental brain metastasis model of human lung cancer, the combination of macitentan and paclitaxel significantly inhibited the growth of brain metastasis and produced a striking survival prolongation of tumor-bearing mice. Conclusions: The endothelin A and B receptor blockade by macitentan could be a promising therapeutic strategy for brain metastases of non-small cell lung cancer.
&Separation of Seed an AC Electric Field By-products by (1984)

A method for separating constituents of the by-products derived from agricultural processes offers the possibility of recovering their valuable components. Partial sorting by a unique electric field enriches the protein concentration in sunflower-seed meal and cottonseed meal by removing objectionable components such as hulls or gossypot. Enrichment is accomplished by the dynamic forces from an electric field that is created by a set of parallel electrodes encased in a plastic panel and connected to an AC power supply. When the panel is activated, particles on its surface become charged, levitated and transported. When a mixture of particles contacts the panel, a difference in the charge is imparted to the components, opposite directions of transportation occur, and, then, the particles separate. The separation, or sorting, offers an additional possibility for upgrading agricultural products. Properties measured for these products and their separated components are charge, charge-to-mass ratio, size, size distribution, shape, moisture, nitrogen and gossypol. This new and direct method of separating components seems independent of their size and shape, yet it is probably dependent on the charge-to-mass ratio. The single-stage separaffon is an analytical tool that might become an engineering process. The electric panel of the contact type contains, transports and refines materials-all without a cup, conveyor or filter touching the sample. Its promise and versatility warrant considering the panel by itself and in conjunction with other processex
High-efficiency and broadband electro-optic frequency combs using coupled lithium-niobate microresonators (2021)

We demonstrate an electro-optic frequency comb source, based on coupled lithium niobate microresonators, with a factor of 100 higher pump-to-comb conversion efficiency (30%) and 2.4 broader optical bandwidth (117 nm), as compared to the previous broadest electro-optic frequency comb.
Stronger Security of Authenticated Key Exchange. (2006)

Recent work by Krawczyk [10] and Menezes [14] has highlighted the importance of under-standing well the guarantees and limitations of formal security models when using them to prove the security of protocols. In this paper we focus on security models for authenticated key exchange (AKE) protocols. We observe that there are several classes of attacks on AKE protocols that lie outside the scope of the Canetti-Krawczyk model. Some of these additional attacks have already been considered by Krawczyk [10]. In an attempt to bring these attacks within the scope of the security model we extend the Canetti-Krawczyk model for AKE security by providing significantly greater powers to the adversary. Our contribution is a more compact, integrated, and comprehensive formulation of the security model. We then introduce a new AKE protocol called NAXOS and prove that it is secure against these stronger adversaries. 1
Applicability of thin film phase plates in biological electron microscopy (2006)

Presented is an evaluation of phase contrast techniques in transmission electron microscopy. The traditional defocus phase contrast is compared to two recently developed phase plate techniques. One is the Zernike phase contrast transmission electron microscope, the other is the Hilbert differential contrast thransmission electron microscope. The imaging characteristics of each technique are discussed. Phase plate techniques provide improved contrast for ice-embedded biological samples which are a challenge for the conventional defocus phase contrast. The flat spectral response of the Zernike and Hilbert modes extends towards the low frequencies which are severely suppressed in the conventional defocus mode. Target applications for each of the phase contrast techniques are discussed based on the specifics of image formation and spectral transfer.
Methods for the design of microelectronic devices and process flows for manufacturability (1997)

Small feature sizes and reduced tolerances of state-of-the-art microelectronic devices make them extremely sensitive to manufacturing variations. This paper describes two approaches dealing with manufacturing variations: process control and statistical design for manufacturability. Process control seeks to reduce the variability of each process module and statistical design seeks to minimize the impact of the variability. An example illustrates the use of process control to minimize variability. Then, a novel approach for statistical design and its application to statistical optimization of deep submicron CMOS is described. This approach is based on a Markov representation of a process flow that captures the sequential and stochastic nature of semiconductor manufacturing. Using this approach we have been able to predict the variability in device performance for a number of process flows. Transistor designs and process flows optimized using this approach show lower variation in key device performances on fabrication.
Understanding and predicting personal navigation (2011)

This paper presents an algorithm that predicts with very high accuracy which Web search result a user will click for one sixth of all Web queries. Prediction is done via a straightforward form of personalization that takes advantage of the fact that people often use search engines to re-find previously viewed resources. In our approach, an individual's past navigational behavior is identified via query log analysis and used to forecast identical future navigational behavior by the same individual. We compare the potential value of personal navigation with general navigation identified using aggregate user behavior. Although consistent navigational behavior across users can be useful for identifying a subset of navigational queries, different people often use the same queries to navigate to different resources. This is true even for queries comprised of unambiguous company names or URLs and typically thought of as navigational. We build an understanding of what personal navigation looks like, and identify ways to improve its coverage and accuracy by taking advantage of people's consistency over time and across groups of individuals.
Comparison of StemPrintER, a novel biology-based genomic predictor of distant recurrence in breast cancer, with Oncotype DX in the TransATAC cohort. (2020)

1020 Background: Accurate prediction of distant metastasis (DM) in early stage ER+/HER2- breast cancer (BC) patients is vital to avoid over/under-treatment with adjuvant chemotherapy (CT). The OncotypeDX Recurrence Score (RS) is a widely used tool to assist clinical decision-making for CT. The StemPrintER Risk Score (SPRS) is an alternative genomic predictor based on the biology of cancer stem cells that predicts recurrence risk in ER+/HER2- BCs (Pece S. et al., EBioMedicine 2019). Here, we analyze the prognostic value of SPRS in the TransATAC cohort of post-menopausal ER+/HER2- BC patients, and compare the prognostic information provided by SPRS and RS for 10-year risk of DM. Methods: The likelihood χ 2 (LRχ 2 ) and Kaplan-Meier survival analyses were used to assess prognostic information provided by SPRS, RS and the clinical treatment score (CTS) in 818 TransATAC patients treated with anastrozole or tamoxifen for 5 years. Comparative analyses were made for DM risk over the 10-year follow-up, as well as in the early (0-5 years) or late (5-10 years) interval, according to nodal status. Results: Used as a continuous variable, SPRS was an independent predictor of DM in years 0-10 among all patients when adjusted for clinical parameters as expressed by the CTS [HR=1.43 (1.18-1.73), P<0.0001], as well as in node-negative [HR=1.51 (1.17-1.94), P=0.001] but not node-positive (N1-3) patients [HR=1.29 (0.95-1.75), P=0.11]. A predefined SPRS cut-off was used to stratify patients into low vs. high risk groups [LOW: N=454, 10-year DM rate=5.8%; HIGH: N=364, 10-year DM rate=21.9%; HR HIGH vs. LOW =2.96 (1.85-4.73); P<0.0001]. SPRS outperformed RS in providing prognostic information for 10-year DM risk (SPRS: HR=1.79, P<0.0001, LRχ 2 =33.4; RS: HR=1.52, P<0.0001, LRχ 2 =22.1), with even greater differences in late DM prediction in N0 patients. SPRS also provided more prognostic information than RS to CTS (ΔLRχ 2 : SPRS+CTS vs. CTS= 14.9; RS+CTS vs. CTS= 9.7). Conclusions: In ER+/HER2- TransATAC BC patients, SPRS was highly prognostic for DM and was superior to RS in providing additional prognostic information to conventional clinicopathological parameters.
Asymmetric synthesis of prostaglandin intermediates (1973)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAsymmetric synthesis of prostaglandin intermediatesJohn J. Partridge, Naresh K. Chadha, and Milan R. UskokovicCite this: J. Am. Chem. Soc. 1973, 95, 21, 7171–7172Publication Date (Print):October 1, 1973Publication History Published online1 May 2002Published inissue 1 October 1973https://pubs.acs.org/doi/10.1021/ja00802a053https://doi.org/10.1021/ja00802a053research-articleACS PublicationsRequest reuse permissionsArticle Views698Altmetric-Citations101LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
New Engineering Thermoplastic Resins Based on Polybutylene Terephthalate (1980)

<div class="htmlview paragraph">Gafite <sup>®</sup> LW molding compounds are impact modified, mica/glass reinforced PBT's (polybutylene terephthalate). They will meet a variety of design and molding criteria for such components as side and rear panels, louvres, deck lids and fender extensions, and are also of interest in other industries where low warpage characteristics are desired.</div> <div class="htmlview paragraph">The Gafite <sup>®</sup> LW polyester compounds essentially eliminate out of mold warpage while offering greater mechanical strength, resistance to environmental aging, resistance to high humidity, resistance to automotive fluids and lower sensitivity to regrind at comparable warpage than the conventional mineral filled nylon systems currently used for exterior automotive parts.</div> <div class="htmlview paragraph">Key advantages of Gafite <sup>®</sup> LW compounds over conventional PBT and mineral filled nylons will be discussed in depth.</div>
“Atypical p-ANCA” in IBD and hepatobiliary disorders react with a 50-kilodalton nuclear envelope protein of neutrophils and myeloid cell lines (2000)

Atypical p-ANCA in UC, PSC, or AIH recognize a 50-kilodalton myeloid-specific nuclear envelope protein.
Helmholtz equation least squares method for transient nearfield acoustic holography (2003)

The generalized Helmholtz equation least squares (HELS) formulations for reconstructing transient acoustic radiation from an arbitrary object subject to an arbitrary time-dependent excitation are derived. To facilitate the derivations, the Laplace transform is employed and the vibro-acoustic quantities on the source surface are solved explicitly in terms of the acoustic pressures measured on a conformal surface around the source at close range multiplied by transfer functions in the Laplace domain first. The vibro-acoustic responses in the time domain can then be expressed as convolution integrals of the measured acoustic pressure signals over temporal kernels. Replacing the spherical Hankel functions in the transfer functions with polynomial expressions, we can recast the infinite integrals in the inverse Laplace transform as contour integrals and evaluate the temporal kernels by using residue theorem. Once the temporal kernels are determined, the vibro-acoustic quantities anywhere in the field, including those on the source surface can be reconstructed directly. Numerical examples of reconstruction of transient acoustic radiation from a baffled disk subject to impulsive and arbitrarily time-dependent excitations are demonstrated. [Work supported by NSF.]
Neutral contrast MRI for the detection of peripheral arterial wall calcifications (2014)

Background Peripheral arterial disease (PAD) is a potentially debilitating condition affecting more than 200 million people worldwide. CT angiography (CTA) has become the preferred modality of vascular surgeons for the imaging evaluation of PAD, because of its simplicity and widespread availability. However, vessel wall calcifications, frequently present in diabetic and elderly patients, diminish its clinical utility (1). MR angiography (MRA) is also an accurate test for PAD (2). Unlike CTA, vessel wall calcifications are invisible with MRA and do not impair diagnostic accuracy. However, the invisibility of calcifications is also a substantial deficiency given that the distribution and severity of vessel wall calcifications have clinical implications for interventional treatment strategy (3), and the presence of vessel wall calcifications contributes additional risk for morbidity and mortality. In order to overcome this significant limitation, we have implemented a novel “neutral contrast 3D
Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive FOXP3 <sup>high</sup> regulatory T cells in humans (2015)

CD4(+) regulatory T (Treg) cells expressing CD25 and the transcription factor forkhead box P3 (FOXP3) are indispensable for immunological self-tolerance and homeostasis. FOXP3(+)CD25(+)CD4(+) T cells in humans, however, are heterogeneous in function and differentiation status, including suppressive or nonsuppressive cells as well as resting or activated Treg cells. We have searched for cell surface markers specific for suppression-competent Treg cells by using a panel of currently available monoclonal antibodies reactive with human T cells. We found that CD15s (sialyl Lewis x) was highly specific for activated, terminally differentiated, and most suppressive FOXP3(high) effector Treg (eTreg) cells and able to differentiate them in various clinical settings from nonsuppressive FOXP3(+) T cells secreting inflammatory cytokines. For example, CD15s(+)FOXP3(+) eTreg cells were increased in sarcoidosis, whereas it was nonsuppressive CD15s(-)FOXP3(+) T cells that were expanded in lupus flares. FOXP3(+) cells induced from conventional CD4(+) T cells by T-cell receptor stimulation hardly expressed CD15s. CD15s(+)CD4(+) T-cell depletion was sufficient to evoke and enhance in vitro immune responses against tumor or viral antigens. Collectively, we have identified CD15s as a biomarker instrumental in both phenotypic and functional analysis of FOXP3(+)CD4(+) T-cell subpopulations in health and disease. It allows specific targeting of eTreg cells, rather than whole FOXP3(+)CD4(+) T cells, in controlling immune responses.
Subcategory-Aware Convolutional Neural Networks for Object Proposals and Detection (2017)

In Convolutional Neural Network (CNN)-based object detection methods, region proposal becomes a bottleneck when objects exhibit significant scale variation, occlusion or truncation. In addition, these methods mainly focus on 2D object detection and cannot estimate detailed properties of objects. In this paper, we propose subcategory-aware CNNs for object detection. We introduce a novel region proposal network that uses subcategory information to guide the proposal generating process, and a new detection network for joint detection and subcategory classification. By using subcategories related to object pose, we achieve state of-the-art performance on both detection and pose estimation on commonly used benchmarks.
An RSV Live-Attenuated Vaccine Candidate Lacking G Protein Mucin Domains Is Attenuated, Immunogenic, and Effective in Preventing RSV in BALB/c Mice (2022)

Removal of the G-protein mucin domains produced RSV LAV candidates that were highly attenuated with retained immunogenicity.
Synthetic cephalosporins. VI. Synthesis and antibacterial activity of 7-((Z)-2-(2-aminothiazol-4-yl)-2-(1-carboxy-1-methyl)ethoxyiminoacetamido)-3-(3-hydroxy-4-pyridon-1-yl)methyl-3-cephem-4-carboxylic acid and related compounds. (1990)

Synthesis and antibacterial activity of 7-[(Z)-2-(2-aminothiazol-4-yl)-2-(1-carboxy-1-methyl)ethoxyimin oacetamido]- 3-(3-hydroxy-4-pyridon-1-yl)-3-cephem-4-carboxylic acid (12) and its related compounds are described. Compound 12 exhibited excellent antibacterial activity against gram-negative bacteria, and its anti-pseudomonal activity was ten to fifteen times greater than that of ceftazidime.
Asian Citrus Psyllid Feeding Behavior in Citrus Treated with Specific and Non-Specific dsRNA (2021)

The potential of RNA interference (RNAi) technology to control the Asian Citrus psyllid (ACP), vector of Huanglongbing (HLB), has been demonstrated in different publications. RNAi is a natural biological process that specifically down regulates the expression of a specific gene, being more environmentally friendly approach to control insects. We´re interested to understand if the treatment of a plant with dsRNA could induce an ACP response. To evaluate if ACP sense the presence of a dsRNA (ACP-specific and non-specific) in plants, we set up free of choice experiments to examined psyllid response to dsRNA treated plants versus non-treated plants, to dsRNA-specific versus dsRNA non-specific and plants treated with two dsRNA-specific. Four groups of 4 plant flush each (2 of each treatment) were placed in each corner of a cage, and 50 ACP were release at the center. They were observed for 15 d, and the number of ACP on each flush recorded daily. Each experiment was repeated at least four times. No significant differences, using F-test analyses, was observed in ACP feeding preferences regarding the presence of dsRNA (p< 0,05). These preliminary results suggest that psyllids appear not to be sensitive to dsRNA ingestion, as they may be for traditional chemical insecticides, thus were not repelled.
The effect of polymer host on volume phase holographic recording properties (1977)

Abstract We have studied the effect of unsaturated‐polyester and epoxy hosts on the volume phase holographic recording properties of media using camphorquinone and 2, 3‐pentanedione as guests. The sensitivity, determined by holographic diffraction efficiency on exposure to an Ar + laser, was used as a probe for the chemical behavior of the medium. Intramolecular, photochemical reactions involving 2, 3‐pentanedione in the epoxy hosts are less effective than in the polyesters. For inter‐molecular reactions initiated by photoexcited camphorquinone, media having polyester hosts are again more sensitive. The availability in unsaturated‐polyester hosts of residual monomer for free‐radical addition reactions is a determining factor in the recording mechanism.