gebhart/patrepeval huggingface dataset:
Resistive switching of aluminum oxide for flexible memory (2008)

The unipolar resistive switching of the Al∕AlxOy∕Al structure is investigated for nonvolatile memory. Following the production of aluminum oxide film (AlxOy) by plasma oxidation, a high ratio of on-state and off-state currents (⩾104) is achieved, and characteristics of switching endurance are reported. Due to the good ductility of aluminum, the performance of resistive switching on a flexible substrate is not degraded by severe substrate bending. The low process temperature of the plasma oxidation process is advantageous for the fabrication of flexible electronic devices and modern interconnection processes.
FATIGUE STRENGTH ENHANCEMENT BY MEANS OF WELD DESIGN CHANGE AND THE APPLICATION OF ULTRASONIC IMPACT TREATMENT (2001)

Over the past four years extensive research has been done in the area of fatigue enhancement of fracture critical details on bridges. This includes the aspect of evaluating different weld designs and post weld treatment approaches. With the development of high strength steels and their use within the bridge industry further emphasis has been placed on this research.
Immunomodulation against microbial pathogens through dendritic cells (2013)

Dendritic cells (DCs) are the most potent antigen presenting cells (APCs), being a key player in the regulation of the adaptive immune response. These immune cells are in their immature form in circulation and peripheral tissues, being able to take up, process and activate the antigen-presenting pathway by the interaction of antigen-loaded Major Histocompatibility Complex molecules class I (MHC class I) and II with, respectively,CD4+ and CD8+ T cells, which will then stimulate Cytotoxic T Lymphocytes (CTL) and Th cells. As a result, this heterogeneous population, present in lymphoid and nonlymphoid organs, is fundamental to survey tissues for foreign antigens and thus to induce an effective immune response, but also, on the other hand, to maintain tolerance against self or harmless antigens. In this review we will explore the interplay between DCs subpopulations and microbial pathogens, highlighting their role as regulators in health and infectious diseases. In addition, we will emphasize progress in our understanding of immunomodulatory strategies, namely those based on nanodelivery systems used to promote host protection through the delivery of antigens to DCs and their presentation to T-cells, being these important factors to have in consideration when developing an effective vaccine.
Pathotropic targeting advances clinical oncology: Tumor-targeted localization of therapeutic gene delivery (2010)

The advent of pathotropic (disease-seeking) targeting has transported genetic medicine across the threshold of history with the progressive clinical validation of Rexin-G, a tumor-targeted nanosized anti-cancer agent. Achieving noteworthy single-agent efficacy and survival benefits in otherwise intractable cancers, the molecular biotechnology platform has stimulated intense interest in the underlying mechanisms-of-action. This report exhibits the effective localization of Rexin-G nanoparticles within a metastatic liver lesion, as observed upon its surgical excision.
Application of Nanopore of Solid Membrane for Recognition of fluorescent Pseudomonas (2017)

The uses of biosensors for sensitive and specific detection of various analytes are of great importance, and its success is often dictated by the nature of the detection element (the specific ligand) and the choice of target analytes. The conventional agriculture caused considerable impacts on soils and waters. It is important to change certain agricultural managements to environmental cleaner techniques. The sustainable agriculture has pointed many approaches and techniques to reduce environmental impact. One of those strategies is the utilization of the soil microbiota to induce plant growth, control of plant diseases and biodegradation of xenobiotic compounds. Studies on the relationship between roots and microbiota are essential to achieve agricultural applications. These studies indicate that one of the most abundant microorganisms in the rhizosphere (area around the roots) is fluorescent Pseudomonas spp. They have been considered as an alternative to agrochemicals for controlling plant diseases and increasing plant development. In the present study gold coated polycarbonate membrane of pore size 100 nm was used. The coated membrane carries carboxylic, thiol and hydroxyl groups. Carboxylic groups are being activated by treating the coated nanoporous membrane with the NHS-EDC linker for the binding of antibodies against the pathogen (fluorescent Pseudomonas) to be detected. After the activation of the membrane, antibodies (which are generated against the fluorescent Pseudomonas) were immobilized over the membrane in the humid chamber. After leaving it for an hour, unbound antibodies were washed by Phosphate buffer Saline. The remaining sites on membrane were then blocked by the Bovine serum albumin. The membrane was then subjected for the detection of pathogen by the electrochemical immunosensor by observing the change in the impedance value. The characterization of such membrane was done by Fourier Transform Infrared Spectroscopy (FT-IR), Scanning Electron Microscopy (SEM), Energy Dispersive Spectroscopy (EDS) and Thermo gravimetric Analyzer (TGA).
Gene Therapy for Wiskott-Aldrich Syndrome—Long-Term Efficacy and Genotoxicity (2014)

Wiskott-Aldrich syndrome (WAS) is characterized by microthrombocytopenia, immunodeficiency, autoimmunity, and susceptibility to malignancies. In our hematopoietic stem cell gene therapy (GT) trial using a γ-retroviral vector, 9 of 10 patients showed sustained engraftment and correction of WAS protein (WASP) expression in lymphoid and myeloid cells and platelets. GT resulted in partial or complete resolution of immunodeficiency, autoimmunity, and bleeding diathesis. Analysis of retroviral insertion sites revealed >140,000 unambiguous integration sites and a polyclonal pattern of hematopoiesis in all patients early after GT. Seven patients developed acute leukemia [one acute myeloid leukemia (AML), four T cell acute lymphoblastic leukemia (T-ALL), and two primary T-ALL with secondary AML associated with a dominant clone with vector integration at the LMO2 (six T-ALL), MDS1 (two AML), or MN1 (one AML) locus]. Cytogenetic analysis revealed additional genetic alterations such as chromosomal translocations. This study shows that hematopoietic stem cell GT for WAS is feasible and effective, but the use of γ-retroviral vectors is associated with a substantial risk of leukemogenesis.
Highly textured and conductive undoped ZnO film using hydrogen post-treatment (1997)

We proposed a method to enhance the characteristics of undoped ZnO films by H2 post-treatment using photochemical vapor deposition. The resistivity of a H2-treated film decreased from 1×10−2 to 2×10−3 Ω cm, the haze ratio increased from 37% to 48%, and no degradation of total transmittance was observed. There are two possible explanations for these phenomena. First, hydrogen atoms assist the desorption of oxygen atoms from the film, resulting in decreased resistivity. Second, hydrogen atoms etch small grains growing among large ones on the surface of the film, resulting in a rough surface.
Identification and genetic mapping of elongated uppermost internode gene eui with microsatellite markers in rice (Oryza sativa L.) (2009)

Development of cytoplasmic male sterile (CMS) lines with elongated uppermost internode (EUI) trait is a desirable alternative to eliminate the use of GA3 in hybrid rice production. In this study, a simple and reliable PCR based, simple sequence repeats (SSR) markers was identified, for the eui gene to facilitate marker assisted selection (MAS). A total of 28 SSR markers, mapped in the vicinity of the genomic clone AC130605 (PD0010D04), were chosen for assessing the polymorphism between IR58025B and IR91-1591-3. A set of 151 F2 plants derived from the cross IR58025B/IR91-1591-3 were surveyed using 15 polymorphic SSR markers. Analysis using MAPMAKER 3.0 revealed that seven SSR markers viz., RM6054, RM3870, RM3476, RM5970, RM7801, RM7446 and RM3620 were linked with euilocus at the genetic distance ranging from 1.0 to 7.1 cM with EUI phenotype. Furthermore, these markers were validated in – F2 (IR58025A/IR91-1591-3) and backcross (IR58025B/IR91-1591-2//IR58025B) population segregating for euigene. The SSR markers reported in this study might be useful for the incorporation of eui gene into CMS lines of rice through marker-assisted backcrossing.

	 

	Key words: Rice, cytoplasmic male sterility, elongated uppermost internode, microsatellites, marker assisted selection, panicle exsertion.
Approximating elementary functions with symmetric bipartite tables (1999)

This paper presents a high-speed method for function approximation that employs symmetric bipartite tables. This method performs two parallel table lookups to obtain a carry-save (borrow-save) function approximation, which is either converted to a two's complement number or is Booth encoded. Compared to previous methods for bipartite table approximations, this method uses less memory by taking advantage of symmetry and leading zeros in one of the two tables. It also has a closed-form solution for the table entries, provides tight bounds on the maximum absolute error, and can be applied to a wide range of functions. A variation of this method provides accurate initial approximations that are useful in multiplicative divide and square root algorithms.
Fast and effective algorithms for graph partitioning and sparse-matrix ordering (1997)

Graph partitioning is a fundamental problem in several scientific and engineering applications. In this paper, we describe heuristics that improve the state-of-the-art practical algorithms used in graph-partitioning software in terms of both partitioning speed and quality. An important use of graph partitioning is in ordering sparse matrices for obtaining direct solutions to sparse systems of linear equations arising in engineering and optimization applications. The experiments reported in this paper show that the use of these heuristics results in a considerable improvement in the quality of sparse-matrix orderings over conventional ordering methods, especially for sparse matrices arising in linear programming problems. In addition, our graph-partitioning-based ordering algorithm is more parallelizable than minimum-degree-based ordering algorithms, and it renders the ordered matrix more amenable to parallel factorization.
Vision of the Future: Capecitabine (2001)

Capecitabine is a thymidine phosphorylase (TP)-activated oral fluoropyrimidine, rationally designed to generate 5-fluorouracil (5-FU) preferentially within tumors. This tumor selectivity is achieved through exploitation of the significantly higher activity of TP in tumor compared with healthy tissue. The high single-agent activity of capecitabine in breast and colorectal cancer suggests that capecitabine may have a role in the treatment of other tumor types that are sensitive to 5-FU, such as pancreatic cancer. Tumor types known to have a high level of TP activity, such as renal cancer, are especially attractive targets for capecitabine therapy. Capecitabine has potential as monotherapy in these tumor types, or as a combination partner for other cytotoxic agents with different mechanisms of action and little overlap of key toxicities. In particular, some cytotoxic drugs, such as the taxanes and cyclophosphamide, are known to upregulate TP activity in tumor tissue, offering the potential for synergistic action. The combination of capecitabine and docetaxel has demonstrated significant activity in women with anthracycline-pretreated breast cancer, and is the only cytotoxic combination to significantly increase survival compared with standard therapy in this setting. In addition, capecitabine as monotherapy or in combination with other cytotoxic agents has shown encouraging activity in pancreatic, ovarian, and renal cell cancers. This article discusses recent data from clinical trials investigating capecitabine in a range of tumor types, highlighting the potential future role of capecitabine as an alternative to traditional i.v. chemotherapy.
An Analytic Model-Based Approach for Power System Alarm Processing Employing Temporal Constraint Network (2009)

The alarm-processing problem is to interpret a large number of alarms under stress conditions, such as faults or disturbances, by providing summarized and synthesized information instead of a flood of raw alarm data. Alarm timestamps represent the temporal relationship among event occurrences and consist of rich and useful information for alarm processing. However, the temporal information has not been well utilized in existing alarm-processing methods. The temporal constraint network (TCN) is a type of directed acyclic graph suitable for representing temporal logics. Based on TCN, a new analytic model is developed for alarm processing with temporal information taken into account. Three major modules are included in the developed approach or alarm processor (i.e., alarm selection, event analysis, and result evaluation). In the alarm selection module, reported alarms are divided into related groups. The function of the event analysis module is to find out what events cause the reported alarms and to estimate when these events happen. The result evaluation module is used to identify abnormal or missing alarms. Finally, two alarm-processing scenarios of an actual power system are served for demonstrating the feasibility and efficiency of the developed approach.
Role-based Privacy Control for Health Information Systems (2003)

This research focuses on establishing a comprehensive and solid privacy control mechanism for health information systems.
Fast Cell Group Selection Scheme for Improving Downlink Cell Edge Performance (2006)

This paper proposes an effective solution for improving downlink cell edge performance-fast cell group selection (FCGS) scheme. The definition and features of FCGS are illustrated and intra-node B FCGS and inter-node B FCGS schemes are explained respectively. The advantages of FCGS vs. hard handover, soft handover and fast cell selection are analyzed. Finally, the capacity analyses and simulation results of downlink cell edge user performance of sectoring and non-sectoring cellular system using above solutions are given
Striking Regression of Temporal Lobe Necrosis Following Radiotherapy for Nasopharyngeal Carcinoma in a Clinical trial of Anti-Mycobacterium Therapy (2014)

The mechanism of radiation-induced delayed brain injuries remains poorly understood, and few treatment options are available. The aim of this study was to investigate whether temporal lobe necrosis can be reversed by anti-mycobacterium therapy (AMT). We conducted this prospective, controlled study in southern China. Ten patients with symptomatic delayed radiation injury were monitored during AMT and compared with a control group of 11 patients who received current standard therapies. Activities of daily living were assessed by the Barthel Index (BI) at study entry and after 2 years of therapy. Magnetic resonance imaging (MRI) was performed before treatment, and changes were monitored during the study. Kaplan–Meier analysis was employed to delineate time-related mortality. A significant treatment effect was observed in the AMT group. The patients’ headaches, seizures, dizziness, and cognitive deterioration rapidly improved. BI improved in the AMT treatment group compared with the control group after 2 years (Mann–Whitney U test; P=0•001). Abnormalities of the temporal lobes, observed by MRI, markedly decreased over time in eight patients, whereas in the control group significant BI deterioration was observed (Wilcoxon signed-rank test; P=0•003) and the patients did not show favorable MRI changes. By 24 months, there was a significant difference between the AMT and control groups with respect to survival time (log-rank test; P=0•011). The results of the present study suggest that radiation necrosis of the brain can be successfully managed by AMT. These findings must be confirmed in large, double-blind, randomized clinical trials.
Towards a dynamic-update-enabled JVM (2009)

This paper advocates that de facto dynamic updates of Java applications will eventually require a dynamic-update-enabled Java virtual machine. We argue that our approach for dynamic updates of component-based Java applications complements the new module system planned for upcoming Java releases. We conclude that simple extensions to an existing JVM can bring full flexibility and transparency to dynamic updates in Java.
Dark Current Measurements on a State of the Art Near-IR HgCdTe 1024x1024 Array (2001)

The NASA/GSFC Detector Characterization Laboratory (DCL) has acquired, for the HST Wide Field Camera 3 project, a preliminary engineering HgCdTe, 1024x1024, 18.5 m m pitch array manufactured by Rockwell Science Center. The device is designed for the near infrared with a cut-off at approximately 1.73 m m and a dark current at 150K of 0.2 e - /sec/pixel. We have made measurements at the DCL to confirm that this preliminary device meets the design specifications. In order to achieve the most reliable results for the dark current, three techniques were used that mitigated non-linear drift problems. We discuss the viability of these methods for determining dark current and the results of the measurements on the device.
NPE: Neural Personalized Embedding for Collaborative Filtering (2018)

Matrix factorization is one of the most efficient approaches in recommender systems. However, such algorithms, which rely on the interactions between users and items, perform poorly for "cold-users" (users with little history of such interactions) and at capturing the relationships between closely related items. To address these problems, we propose a neural personalized embedding (NPE) model, which improves the recommendation performance for cold-users and can learn effective representations of items. It models a user's click to an item in two terms: the personal preference of the user for the item, and the relationships between this item and other items clicked by the user. We show that NPE outperforms competing methods for top-N recommendations, specially for cold-user recommendations. We also performed a qualitative analysis that shows the effectiveness of the representations learned by the model.
Automatically adapting web sites for mobile access through logical descriptions and dynamic analysis of interaction resources (2008)

While several solutions for desktop user interface adaptation for mobile access have been proposed, there is still a lack of solutions able to automatically generate mobile versions taking semantic aspects into account. In this paper, we propose a general solution able to dynamically build logical descriptions of existing desktop Web site implementations, adapt the design to the target mobile device, and generate an implementation that preserves the original communications goals while taking into account the actual resources available in the target device. We describe the novel transformations supported by our new solution, show example applications and report on first user tests.
Bacteria-Mediated Lithography of Polymer Surfaces (1996)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTBacteria-Mediated Lithography of Polymer SurfacesA. Aherne, C. Alexander, M. J. Payne, N. Perez, and E. N. VulfsonView Author Information Macromolecular Sciences Department Institute of Food Research Reading Laboratory, Earley Gate Whiteknights, Reading RG6 6BZ, U.K. Cite this: J. Am. Chem. Soc. 1996, 118, 36, 8771–8772Publication Date (Web):September 11, 1996Publication History Received16 January 1996Published online11 September 1996Published inissue 1 January 1996https://pubs.acs.org/doi/10.1021/ja960123chttps://doi.org/10.1021/ja960123crapid-communicationACS PublicationsCopyright © 1996 American Chemical SocietyRequest reuse permissionsArticle Views1194Altmetric-Citations114LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Bacteria,Fluorescence,Genetics,Pharmaceuticals,Polymers Get e-Alerts
MiniRISC CW4001-a small, low-power MIPS CPU core (2002)

The MiniRISC CW4001 is a small, low-power RISC CPU core that implements the MTPS-2 ISA. The CW4001 CPU Core is 3.5 mm/sup 2/ in area (two-layer metal) and is implemented in LSI Logic's LCB500K 0.5-micron drawn cell-based ASIC technology. Operating frequency when used in an ASIC is up to 60 MHz under worst case conditions (slow process, 3.15 V, 70 C). Power is estimated to be 2 mW/MHz. Peak performance when running out of on-chip cache is 48 MIPS (assuming 25% loads/stores). Target applications are cost and/or power-constrained applications, such as portable telecommunications, handheld computing, and consumer multimedia. In addition to the CW4001 CPU core, several key bolt-ons are designed, including an MMU, a Basic Bus Interface/Cache Controller (BBCC), a Fast Multiply/Divide Unit (MDU), and Timers. The CW4001 CPU Core and selected bolt-ons have been implemented in silicon in the MR4001 Lead Vehicle.
Automatic Speechreading with Applications to Human-Computer Interfaces (2002)

There has been growing interest in introducing speech as a new modality into the human-computer interface (HCI). Motivated by the multimodal nature of speech, the visual component is considered to yield information that is not always present in the acoustic signal and enables improved system performance over acoustic-only methods, especially in noisy environments. In this paper, we investigate the usefulness of visual speech information in HCI related applications. We first introduce a new algorithm for automatically locating the mouth region by using color and motion information and segmenting the lip region by making use of both color and edge information based on Markov random fields. We then derive a relevant set of visual speech parameters and incorporate them into a recognition engine. We present various visual feature performance comparisons to explore their impact on the recognition accuracy, including the lip inner contour and the visibility of the tongue and teeth. By using a common visual feature set, we demonstrate two applications that exploit speechreading in a joint audio-visual speech signal processing task: speech recognition and speaker verification. The experimental results based on two databases demonstrate that the visual information is highly effective for improving recognition performance over a variety of acoustic noise levels.
Incomplete information in object-oriented databases (1990)

We present a way to handle incomplete information both at schema and object instance level in an object-oriented database. Incremental schema design becomes possible with the introduction of generic classes. Incomplete data in an object instance is handled with the introduction of explicit null values in a similar way as in the relational and nested relations data models.