gebhart/patrepeval huggingface dataset:
An 800 MS/s Dual-Residue Pipeline ADC in 40 nm CMOS (2011)

This paper presents a 12-bit dual-residue pipeline ADC allowing the use of low gain and low bandwidth residue amplifiers to achieve 59 dB peak SNDR at 800 MSample/s. The dual-residue architecture is insensitive to the open-loop gain and the bandwidth of the residue amplifiers. However, their offset limits the accuracy of the entire ADC and therefore a background offset calibration technique was implemented. The high sampling speed was obtained through four times interleaving, requiring gain and offset calibration between the interleaved ADC lanes. The ADC was realized in a standard 40 nm CMOS technology, operates from a dual 1 V/2.5 V power supply, utilizes an input range of 1.2 V peak-to-peak differential, and consumes 105 mW.
Very strong hydrogen bonding (1980)

The first page of this article is displayed as the abstract.
Concurrent reduction and modification of polyaniline emeraldine base with pyrrolidine and other nucleophiles (1997)

Polyaniline emeraldine base 1 can be easily modified by pyrrolidine and other nucleophiles, e.g. piperidine, morpholine, alkane-1-thiols and mercaptoacetic acid, presumably via a concurrent reduction and substitution mechanism.
Cooking Up an Interactive Olfactory Game Display (2008)

It's long been possible to give users outside an actual environment that environment's visual and auditory information and thus contribute to establishing presence. However, we've yet to establish much presence when users require olfactory information - such as in environments focused on foods, flowers, perfumes, or, in some cases, more offensive smells. Recently, several VR researchers have become interested in olfaction and olfactory displays that present smells in virtual environments (VEs). In this article, we describe our interactive olfactory display. One of our development goals is to confirm the assumption that users' interactions with the system increases presence. Thus, we used our interactive olfactory display to develop a cooking game in collaboration with electronic engineers and artists.
Sequential Use of Paraformaldehyde and Methanol as Optimal Conditions for the Direct Quantification of ZEBRA and Rta Antigens by Flow Cytometry (2000)

A technique was developed with flow cytometry to quantify the two immediate-early proteins ZEBRA and Rta, which are involved in the activation of Epstein-Barr virus replication. We evaluated four monoclonal antibodies on four cell lines (B95-8, RAJI, Namalwa, and P3HR1) with varying levels of expression of these replication-phase antigens. The Namalwa lymphoma cell line was used as a negative control. Four fixation-permeabilization procedures were compared. The preparation of cells with paraformaldehyde and methanol in sequence, and antigen detection with AZ125 and AR 5A9 monoclonal antibodies, were found to be the optimal conditions in these cell lines. Our procedure allowed ZEBRA antigen to be detected in 4.85% of peripheral blood mononuclear cells from a transplant recipient with a lymphoproliferative disease.
Nanosecond-pulsed plasma actuation in quiescent air and laminar boundary layer (2014)

An experimental investigation of the working principles of a nanosecond-pulsed dielectric barrier discharge (ns-DBD) plasma actuator has been conducted. Special emphasis is given on the thermal effects accompanying the rapid deposition of energy associated with this kind of actuation. A ns-DBD plasma actuator has been operated in quiescent air conditions as well as in a flat plate laminar boundary layer, with external flow velocity of 5 and 10 m s−1. Schlieren imaging and particle image velocimetry have been used to characterize the actuation. Additionally, the back-current shunt technique has been used for current measurements, from which energy input (per pulse) is calculated. Cases of 10-, 20- and 50-pulse bursts are tested. Schlieren imaging in still air conditions shows the formation of a high-temperature region in the vicinity of the discharge volume. The spatial extent of the visible 'hot spot' depends upon the number of pulses within the burst, following a power law. Schlieren imaging of the span-wise effect of the plasma actuator reveals weak compression waves originating from the loci of discharge filaments. The thermal 'hot spots' exhibit significant three-dimensionality. Particle image velocimetry is used to measure the velocity field resulting from the ns-DBDs acting on a laminar boundary layer. The disturbance leads to formation of a Tollmien–Schlichting wave train, with spectral content in good agreement with linear stability theory. It is observed that the group length of the wave train is proportional to the number of pulses within the burst.
Inhibition of heat shock (stress) protein induction by deuterium oxide and glycerol: Additional support for the abnormal protein hypothesis of induction (1989)

The patterns of radioactively labeled proteins from cultured chicken embryo cells stressed in the presence of either D2O or glycerol were analyzed by using one-dimensional polyacrylamide gel electrophoresis. These hyperthermic protectors blocked the induction of stress proteins during a 1-hour heat shock at 44 degrees C. The inhibitory effect of glycerol but not D2O on the induction of heat shock proteins could be overcome by increased temperature. By using transcriptional run-on assays of isolated nuclei and cDNA probes to detect hsp70- and hsp88-specific RNA transcripts, it was shown that the D2O and glycerol blocks occurred at or before transcriptional activation of the hsp70 and hsp88 genes. After heat-stressed cells were returned to 37 degrees C and the protectors were removed, heat shock proteins were inducible by a second heating. This result and the fact that the chemical stressor sodium arsenite induced stress proteins in glycerol medium indicated that the treatments did not irreversibly inhibit the induction pathways and that the stress response could be triggered even in the presence of glycerol by a stressor other than heat. In principle then, cells incurring thermal damage during a 1-hour heat shock at 44 degrees C in D2O or glycerol medium should be competent to respond by inducing heat shock proteins during a subsequent recovery period at 37 degrees C in normal medium. We found that heat shock proteins were not induced in recovering cells, suggesting that glycerol and D2O protected heat-sensitive targets from thermal damage. Evidence that the heat-sensitive target(s) is likely to be a protein(s) is summarized. During heat shocks of up to 3 hours duration, neither D2O nor glycerol significantly altered hsp23 gene activity, a constitutively expressed chicken heat shock gene whose RNA transcripts and protein products are induced by stabilization (increased half-life). During a 2-hour heat shock, glycerol treatment blocked the heat-induced stabilization of hsp23 RNA and proteins; however, D2O treatment only blocked RNA transcript stabilization, effectively uncoupling the hsp23 protein stabilization pathway from hsp23 RNA stabilization and transcriptional activation of hsp70 and hsp88 genes.
Analysis of dielectric constant of a self-forming barrier layer with Cu–Mn alloy on TEOS-SiO2 (2009)

A Cu–Mn alloy film was deposited on SiO2 to self-form a diffusion barrier layer of MnOx at their interface. Transmission electron microscopy revealed that the barrier layer was formed not on the Cu alloy side but on the SiO2 side. Capacitance-voltage measurement revealed the decrease in the dielectric constant of the barrier layer from 11.4 to 5.1 with increasing annealing temperature. The obtained results indicated that the self-forming barrier layer with Cu–Mn is an excellent barrier layer without posing any negative influences on the interconnect line resistance and on the insulator capacitance.
Survey of Plant Density Tolerance in U.S. Maize Germplasm (2013)

ABSTRACT A broad range of U.S. maize ( Zea mays L.) germplasm was evaluated for plant density tolerance (PDT) to identify potential sources of favorable alleles and to obtain a better understanding the underlying genetics involved. Thirty‐two hybrids created using a set of inbreds representing parentage of key heterotic subgroups were evaluated at plant densities ranging from 47,000 (19,000 plants per acre [ppA]) to 133,000 plants ha −1 (54,000 ppA). Forty‐eight phenotypic traits from five categories (photosynthetic capability, plant architecture, growth responses, source–sink relationship, and general stress tolerance) as well as grain yield were evaluated in three environments that differed for levels of soil moisture availability. The relationship between plant density and grain yield was assessed for each hybrid, with a wide range of responses observed. Five hybrids showed substantial tolerance to plant densities ≥116,000 plants ha −1 based on grain yield performance. Phenotypic trait correlations revealed a subset of traits associated with grain yield across plant densities, with all five categories of traits implicated directly; the subset included leaf angle, upper stem diameter, leaf area required to produce a gram of grain, kernel rows per ear, days to canopy closure, barrenness, kernels per plant, kernel length, leaf number, upper leaf area, staygreen, zipper effect, kernels per row, and anthesis–silking interval. Analysis of gene action for grain yield across plant densities emphasized the prominence of additivity, the increasing importance of nonadditivity as plant density and environmental stress levels increased, and genotype by environment interaction. This work paves the way for further characterization of PDT through quantitative trait locus mapping and candidate gene approaches.
Mutations of OCTN2, an Organic Cation/Carnitine Transporter, Lead to Deficient Cellular Carnitine Uptake in Primary Carnitine Deficiency (1999)

Systemic primary carnitine deficiency (CDSP, OMIM 212140) is an autosomal recessive disease characterized by low serum and intracellular concentrations of carnitine. CDSP may present with acute metabolic derangement simulating Reye's syndrome within the first 2 years of life. After 3 years of age, patients with CDSP may present with cardiomyopathy and muscle weakness. A linkage with D5S436 in 5q was reported in a family. A recently cloned homologue of the organic cation transporter, OCTN2, which has sodium-dependent carnitine uptake properties, was also mapped to the same locus. We screened for mutation in OCTN2 in a confirmed CDSP family. One truncating mutation (Trp132Stop) and one missense mutation (Pro478Leu) of OCTN2 were identified together with two silent polymorphisms. Expression of the mutant cDNAs revealed virtually no uptake activity for both mutations. Our data indicate that mutations in OCTN2 are responsible for CDSP. Identification of the underlying gene in this disease will allow rapid detection of carriers and postnatal diagnosis of affected patients.
Direct Synthesis of van der Waals Solids (2014)

The stacking of two-dimensional layered materials, such as semiconducting transition metal dichalcogenides (TMDs), insulating hexagonal boron nitride (hBN), and semimetallic graphene, has been theorized to produce tunable electronic and optoelectronic properties. Here we demonstrate the direct growth of MoS2, WSe2, and hBN on epitaxial graphene to form large-area van der Waals heterostructures. We reveal that the properties of the underlying graphene dictate properties of the heterostructures, where strain, wrinkling, and defects on the surface of graphene act as nucleation centers for lateral growth of the overlayer. Additionally, we show that the direct synthesis of TMDs on epitaxial graphene exhibits atomically sharp interfaces. Finally, we demonstrate that direct growth of MoS2 on epitaxial graphene can lead to a 10(3) improvement in photoresponse compared to MoS2 alone.
Introduction to Microwave Circuits (2001)

"Do you want to design a wireless transmitter or receiver for hand-held telephones? Have you wondered why the printed circuit wires on high-frequency circuits don't always run in a straight line? This valuable text will answer all of your questions regarding component parasitics and circuit characterization for rf/microwave amplifier, oscillator, and filter circuit design and analysis. You will understand why capacitors act as inductors and vice versa and why amplifiers work like oscillators, while oscillators for local area networks work more like local area heaters. Application of the information in Introduction to Microwave Circuits will reduce design-cycle time and costs, markedly increasing the probability of first-time success in printed circuit or monolithic microwave integrated circuit (MMIC) design. Several approaches are taken into consideration, such as the effects of currents on the ground plane, bypass and coupling capacitors, and nonlinear effects in linear circuits.
Novel Three-Dimensional Positioner and Scanner for the STM Using Shear Deformation of Piezoceramic Plates (1988)

A new type of coarse and fine positioner of an STM tip has been developed. The x y -walker has three pairs of composite legs which are made of thickness expansion and thickness shear piezoelectric plates. While one of each pair of legs shrinks, the other leg expands and shear deforms giving rise to one-step displacement. The same type of z -walker is placed on the x y -walker. The position of the tip is finely controlled by shear deformation of the expanded legs. Two pieces of thickness shear piezo plates and a thickness expansion one are stacked for a rigid scanner. Atomic resolution of the STM unit has been confirmed on an air-cleaved MoS 2 surface.
Menaquinone (vitamin K2) therapy for bronchial asthma. II. Clinical effect of menaquinone on bronchial asthma. (1975)

A series of 191 patients with bronchial asthma were treated with menaquinone for not less than one year to investigate the clinical effects of the drug. The clinical effect may be summarized as follows: 1) The therapy with menaquinone only gave an effective rate oo 90.9% (a markedly effective rate of 42.4%) in mild patients, an effective rate of 86.7% (a markedly effective rate of 30.0%) in moderate patients, and effective rate of 72.7% (a markedly effective rate of 27.3%) in severe patients; namely, considerably a high effective rate was attained by the therapy in the respective patients. 2) The therapy with menaquinone, in conjunction with hyposensitization therapy, gave an effective rate of 100% (a markedly effective rate of 33.3%). 3) The double blind study of the clinical effects of menaquinone revealed that placebo used in the study was effective on only 16.7% of the patients treated with it, and that the incidence of recurrence due to withdrawal of meaquinone therapy tended to be low in the patients treated with the drug for a long period of time.
Expression in a baculovirus system of a cDNA encoding human CYP2A6 (1994)

Conference Article| May 01 1994 Expression in a baculovirus system of a cDNA encoding human CYP2A6 MANOJ NANJI; MANOJ NANJI 1Department of Biochemistry and Molecular Biology, University College London, Gower Street, London WC1E 6BT Search for other works by this author on: This Site PubMed Google Scholar PHILIPPE CLAIR; PHILIPPE CLAIR *Department of Biochemistry, Queen Mary and Westfield College, University of London, Mile End Road, London E1 4NS Search for other works by this author on: This Site PubMed Google Scholar ELIZABETH. A. SHEPHARD; ELIZABETH. A. SHEPHARD 1Department of Biochemistry and Molecular Biology, University College London, Gower Street, London WC1E 6BT Search for other works by this author on: This Site PubMed Google Scholar IAN. R. PHILLIPS IAN. R. PHILLIPS *Department of Biochemistry, Queen Mary and Westfield College, University of London, Mile End Road, London E1 4NS Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1994) 22 (2): 122S. https://doi.org/10.1042/bst022122s Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Cite Icon Cite Get Permissions Citation MANOJ NANJI, PHILIPPE CLAIR, ELIZABETH. A. SHEPHARD, IAN. R. PHILLIPS; Expression in a baculovirus system of a cDNA encoding human CYP2A6. Biochem Soc Trans 1 May 1994; 22 (2): 122S. doi: https://doi.org/10.1042/bst022122s Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search This content is only available as a PDF. © 1994 Biochemical Society1994 Article PDF first page preview Close Modal You do not currently have access to this content.
Automatic Picker Developments and Optimization: FilterPicker--a Robust, Broadband Picker for Real-Time Seismic Monitoring and Earthquake Early Warning (2012)

International audience
Phosphate Availability Regulates Root System Architecture in Arabidopsis (2001)

Plant root systems are highly plastic in their development and can adapt their architecture in response to the prevailing environmental conditions. One important parameter is the availability of phosphate, which is highly immobile in soil such that the arrangement of roots within the soil will profoundly affect the ability of the plant to acquire this essential nutrient. Consistent with this, the availability of phosphate was found to have a marked effect on the root system architecture of Arabidopsis. Low phosphate availability favored lateral root growth over primary root growth, through increased lateral root density and length, and reduced primary root growth mediated by reduced cell elongation. The ability of the root system to respond to phosphate availability was found to be independent of sucrose supply and auxin signaling. In contrast, shoot phosphate status was found to influence the root system architecture response to phosphate availability.
Higher order neural networks for financial time series prediction (2017)

Neural networks have been shown to be a promising tool for forecasting financial times series. Numerous research and applications of neural networks in business have proven their advantage in relation to classical methods that do not include artificial intelligence. What makes this particular use of neural networks so attractive to financial analysts and traders is the fact that governments and companies benefit from it to make decisions on investment and trading. However, when the number of inputs to the model and the number of training examples becomes extremely large, the training procedure for ordinary neural network architectures becomes tremendously slow and unduly tedious. To overcome such time-consuming operations, this research work focuses on using various Higher Order Neural Networks (HONNs) which have a single layer of learnable weights, therefore reducing the networks' complexity. In order to predict the upcoming trends of univariate financial time series signals, three HONNs models; the Pi-Sigma Neural Network, the Functional Link Neural Network, and the Ridge Polynomial Neural Network were used, as well as the Multilayer Perceptron. Furthermore, a novel neural network architecture which comprises of a feedback connection in addition to the feedforward Ridge Polynomial Neural Network was constructed. The proposed network combines the properties of both higher order and recurrent neural networks, and is called Dynamic Ridge Polynomial Neural Network (DRPNN). Extensive simulations covering ten financial time series were performed. The forecasting performance of various feedforward HONNs models, the Multilayer Perceptron and the novel DRPNN was compared. Simulation results indicate that HONNs, particularly the DRPNN in most cases demonstrated advantages in capturing chaotic movement in the financial signals with an improvement in the profit return over other network models. The relative superiority of DRPNN to other networks is not just its ability to attain high profit return, but rather to model the training set with fast learning and convergence. The network offers fast training and shows considerable promise as a forecasting tool. It is concluded that DRPNN do have the capability to forecast the financial markets, and individual investor could benefit from the use of this forecasting.
Synthesis and Structural Characterization of Natural Benzofuranoids (2015)

The synthesis of ustusoranes A, B, and E, pergillin, dihydropergillin, (±)-penicisochroman A, and (-)-brassicadiol, starting from optically active (R)-benzolactone, is described. The synthesis of ustusoranes A and E established the absolute configurations of these natural products. The synthesis of pergillin and (±)-penicisochroman A led to the structural revision of aspergiones E and F. This study clearly indicates that (R)-benzolactone is a potential intermediate in the synthesis of natural benzofuranoids.
Crystal Structure of the Minor Pilin CofB, the Initiator of CFA/III Pilus Assembly in Enterotoxigenic Escherichia coli (2015)

Type IV pili are extracellular polymers of the major pilin subunit. These subunits are held together in the pilus filament by hydrophobic interactions among their N-terminal α-helices, which also anchor the pilin subunits in the inner membrane prior to pilus assembly. Type IV pilus assembly involves a conserved group of proteins that span the envelope of Gram-negative bacteria. Among these is a set of minor pilins, so named because they share their hydrophobic N-terminal polymerization/membrane anchor segment with the major pilins but are much less abundant. Minor pilins influence pilus assembly and retraction, but their precise functions are not well defined. The Type IV pilus systems of enterotoxigenic Escherichia coli and Vibrio cholerae are among the simplest of Type IV pilus systems and possess only a single minor pilin. Here we show that the enterotoxigenic E. coli minor pilins CofB and LngB are required for assembly of their respective Type IV pili, CFA/III and Longus. Low levels of the minor pilins are optimal for pilus assembly, and CofB can be detected in the pilus fraction. We solved the 2.0 Å crystal structure of N-terminally truncated CofB, revealing a pilin-like protein with an extended C-terminal region composed of two discrete domains connected by flexible linkers. The C-terminal region is required for CofB to initiate pilus assembly. We propose a model for CofB-initiated pilus assembly with implications for understanding filament growth in more complex Type IV pilus systems as well as the related Type II secretion system.
Energy Consumption Estimation in Embedded Systems (2008)

This paper presents an energy consumption modeling technique for embedded systems based on a microcontroller. The software tasks that run on the embedded system are profiled, and their characteristics are analyzed. The type of executed assembly instructions, as well as the number of accesses to the memory and the analog-to-digital converter, is the required information for the derivation of the proposed model. An appropriate instrumentation setup has been developed for measuring and modeling the energy consumption in the corresponding digital circuits.