gebhart/patrepeval huggingface dataset:
THE CHEMICAL COMPOSITION AND ANTIMICROBIAL ACTIVITY OF ESSENTIAL OILS OF VACCINIUM ARCTOSTAPHYLOS L. (2014)

Objective: The growing resistance of different bacteria to antibiotic chemical drugs have become the global issue. This investigation is the first study of the antimicrobial activity of the essential oil of flowering aerial parts of Vaccinium arctostaphylos. The current research was conducted to evaluate the antibacterial effects of essential oils and hydroalcoholic extract  extracted from aerial parts of Vaccinium arctostaphylos, native species. Methods: The chemical composition of the essential oils extracted by hydrodistillation from the flowering aerial parts of Vaccinium arctostaphylos L. was assessed by the GC and GC/MS analysis. Twentynine different compounds, constituting 86.61% of the oil, were recorded, among which the major compounds were α-Pinene (15.5%), Linalool (11.7%), Sandaracopimaradiene (5.9%) and Safranal (8.8%). The invitro antibacterial activity of the extracted essential oil was evaluated against some Gram positive and negative bacteria.  Results: According to the obtained results from the current research, the essential oil of Vaccinium arctostaphylos showed the antibacterial activities against most of the bacteria tested, including Escherichia coli, Klebsiella pneumoniae, Enterococcus faecalis and Streptococcus pneumonia, contrasted to Staphylococcus aureus. In contrast to the essential oil, the hydroalcoholic extract of Vaccinium arctostaphylos did not display the antibacterial effects against the mentioned microorganisms.
α‐Linolenic acid does not contribute appreciably to docosahexaenoic acid within brain phospholipids of adult rats fed a diet enriched in docosahexaenoic acid (2005)

Adult male unanesthetized rats, reared on a diet enriched in both alpha-linolenic acid (alpha-LNA) and docosahexaenoic acid (DHA), were infused intravenously for 5 min with [1-(14)C]alpha-LNA. Timed arterial samples were collected until the animals were killed at 5 min and the brain was removed after microwaving. Plasma and brain lipid concentrations and radioactivities were measured. Within plasma lipids, > 99% of radioactivity was in the form of unchanged [1-(14)C]alpha-LNA. Eighty-six per cent of brain radioactivity at 5 min was present as beta-oxidation products, whereas the remainder was mainly in 'stable' phospholipid or triglyceride as alpha-LNA or DHA. Equations derived from kinetic modeling demonstrated that unesterified unlabeled alpha-LNA rapidly enters brain from plasma, but that its incorporation into brain phospholipid and triglyceride, as in the form of synthesized DHA, is < or = 0.2% of the amount that enters the brain. Thus, in rats fed a diet containing large amounts of both alpha-LNA and DHA, the alpha-LNA that enters brain from plasma largely undergoes beta-oxidation, and is not an appreciable source of DHA within brain phospholipids.
PENYULUHAN PEMANFAATAN REKAM MEDIK ELEKTRONIK DI INSTALASI RAWAT JALAN RUMAH SAKIT UMUM CUT MEUTIA KABUPATEN ACEH UTARA (2022)

Perkembangan zaman telah menjadikan kebutuhan semakin kompleks. Kebutuhan akan kemudahan dalam mengakses teknologi mengharuskan suatu perusahaan untuk meningkatkan kinerjanya demi memenuhi faktor kepuasan pelanggan Pentingnya penggunaan teknologi informasi mulai disadari oleh organisasi modern, terutama dalam era globalisasi dimana perusahaan/instansi dituntut untuk semakin kompetitif dan berdaya saing. Oleh karena itu menjadi penting untuk memacu tingkat pemanfaatan dan penggunaan teknologi informasi di organisasi. Manfaat penggunaan Rekam Medis Elektronik (RME) telah diakui secara luas. Salah satu manfaatnya adalah pemeriksaan data yang berkelanjutan berkualitas, terutama ketika pembuatan dan pengumpulan data dilakukan secara otomatis. Misalnya data dari perangkat laboratorium, atau dari radiologi. Manfaat lain kemampuan penyimpanan data dalam jumlah besar dalam waktu komputasi singkat, menghasilkan hasil yang handal. Tujuan dari pemanfaatan RME sebagai solusi berbasis Informasi Teknologi (IT) yang dapat meningkatkan pertukaran informasi dan komunikasi antar tenaga kesehatan yang lebih efektif karena data saling terintegrasi. Metode penyuluhan dilakukan menggunakan peresentasi dan interaksi kepada pegawai di Rumah Sakit Umum Cut Meutia Kabupaten Aceh Utara. Kesimpulan akhir dari kegiatan pengabdian masyarakat ini adalah dari kegiatan penyuluhan pegawai dapat mempermudahkan pekerjaanya dengan pemanfaatan rekam medis elektronik di instalasi rawat jalan rumah sakit
Combinatorial control of <i>Drosophila</i> circular RNA expression by intronic repeats, hnRNPs, and SR proteins (2015)

Thousands of eukaryotic protein-coding genes are noncanonically spliced to produce circular RNAs. Bioinformatics has indicated that long introns generally flank exons that circularize in Drosophila, but the underlying mechanisms by which these circular RNAs are generated are largely unknown. Here, using extensive mutagenesis of expression plasmids and RNAi screening, we reveal that circularization of the Drosophila laccase2 gene is regulated by both intronic repeats and trans-acting splicing factors. Analogous to what has been observed in humans and mice, base-pairing between highly complementary transposable elements facilitates backsplicing. Long flanking repeats (∼ 400 nucleotides [nt]) promote circularization cotranscriptionally, whereas pre-mRNAs containing minimal repeats (<40 nt) generate circular RNAs predominately after 3' end processing. Unlike the previously characterized Muscleblind (Mbl) circular RNA, which requires the Mbl protein for its biogenesis, we found that Laccase2 circular RNA levels are not controlled by Mbl or the Laccase2 gene product but rather by multiple hnRNP (heterogeneous nuclear ribonucleoprotein) and SR (serine-arginine) proteins acting in a combinatorial manner. hnRNP and SR proteins also regulate the expression of other Drosophila circular RNAs, including Plexin A (PlexA), suggesting a common strategy for regulating backsplicing. Furthermore, the laccase2 flanking introns support efficient circularization of diverse exons in Drosophila and human cells, providing a new tool for exploring the functional consequences of circular RNA expression across eukaryotes.
Near-Infrared Fluorescence Labeled Anti-TAG-72 Monoclonal Antibodies for Tumor Imaging in Colorectal Cancer Xenograft Mice (2009)

Anti-TAG-72 monoclonal antibodies target the tumor-associated glycoprotein (TAG)-72 in various solid tumors. This study evaluated the use of anti-TAG-72 monoclonal antibodies, both murine CC49 and humanized CC49 (HuCC49deltaCH2), for near-infrared fluorescent (NIR) tumor imaging in colorectal cancer xenograft models. The murine CC49 and HuCC49deltaCH2 were conjugated with Cy7 monofunctional N-hydroxysuccinimide ester (Cy7-NHS). Both in vitro and in vivo anti-TAG-72 antibody binding studies were performed. The in vitro study utilized the human colon adenocarcinoma cell line LS174T that was incubated with Cy7, antibody-Cy7 conjugates, or excessive murine CC49 followed by the antibody-Cy7 conjugates and was imaged by fluorescence microscopy. The in vivo study utilized xenograft mice, bearing LS174T subcutaneous tumor implants, that received tail vein injections of Cy7, murine CC49-Cy7, HuCC49deltaCH2-Cy7, or nonspecific IgG-Cy7 and were imaged by the Xenogen IVIS 100 system from 15 min to 288 h. The biodistribution of the fluorescence labeled antibodies was determined by imaging the dissected tissues. The in vitro study revealed that the antibody-Cy7 conjugates bound to LS174T cells and were blocked by excessive murine CC49. The in vivo study demonstrated that murine CC49 achieved a tumor/blood ratio of 15 at 96 h postinjection. In comparison, HuCC49deltaCH2-Cy7 cleared much faster than murine CC49-Cy7 from the xenograft mice, and HuCC49deltaCH2-Cy7 achieved a tumor/blood ratio of 12 at 18 h postinjection. In contrast, Cy7 and Cy7 labeled nonspecific IgG resulted in no demonstrable tumor accumulation. When mice were injected with excessive unlabeled murine CC49 at 6 h before the injection of murine CC49-Cy7 or HuCC49deltaCH2-Cy7, both the intensity and retention time of the fluorescence from the tumor were reduced. In summary, the Cy7 labeled murine CC49 and HuCC49deltaCH2 demonstrate tumor-targeting capabilities in living colorectal cancer xenograft mice and provide an alternative modality for tumor imaging.
Antitumor Activity of Peptide Amphiphile Nanofiber-Encapsulated Camptothecin (2011)

Self-assembling peptide amphiphile (PA) nanofibers were used to encapsulate camptothecin (CPT), a naturally occurring hydrophobic chemotherapy agent, using a solvent evaporation technique. Encapsulation by PA nanofibers was found to improve the aqueous solubility of the CPT molecule by more than 50-fold. PAs self-assembled into nanofibers in the presence of CPT as demonstrated by transmission electron microscopy. Small-angle X-ray scattering results suggest a slight increase in diameter of the nanofiber to accommodate the hydrophobic cargo. In vitro studies using human breast cancer cells show an enhancement in antitumor activity of the CPT when encapsulated by the PA nanofibers. In addition, using a mouse orthotopic model of human breast cancer, treatment with PA nanofiber-encapsulated CPT inhibited tumor growth. These results highlight the potential of this model PA system to be adapted for delivery of hydrophobic therapies to treat a variety of diseases including cancer.
A Study on Removal of Radial Interference Echo with Weather Radar (2010)

Electromagnetic disturbance (EMI) is an unpredictable event which often cause abnormal radar echo. EMI enables invariant radial interference echo (features such as sun-strobes) existing in certain directions in radar echo charts at many radar stations, the interference echo and the precipitation echo overlap in many regions. The paper key research has analyzed removal of interference echo which laps over precipitation echo, and an algorithm has been proposed. The radial interference echo could be distinguished from precipitation echo by analyzing their differences. According to the wave principle of superposition and the weather radar signal processing principle, the effective precipitation echo power was obtained by processing the echo power, thus disturbance was eliminated. The analyses results show that most of interference echo were detected and removed by the algorithm, especially in the overlap regions. It can eliminate radial interference echo and retain precipitation echo well at the same time.
Variation in the Incidence of Teratomas after the Transplantation of Nonhuman Primate ES Cells into Immunodeficient Mice (2008)

Embryonic stem (ES) cells have the ability to generate teratomas when transplanted into immunodeficient mice, but conditions affecting the generation remain to be elucidated. Nonhuman primate cynomolgus ES cells were transplanted into immunodeficient mice under different conditions; the number of transplanted cells, physical state (clumps or single dissociated cells), transplant site, differentiation state, and immunological state of recipient mice were all varied. The tumorigenicity was then evaluated. When cynomolgus ES cells were transplanted as clumps into the lower limb muscle in either nonobese diabetic/severe combined immunodeficiency (NOD/SCID) or NOD/SCID/?cnull (NOG) mice, teratomas developed in all the animals transplanted with 1 × 105 or more cells, but were not observed in any mouse transplanted with 1 × 103 cells. However, when the cells were transplanted as dissociated cells, the number of cells necessary for teratomas to form in all mice increased to 5 × 105. When the clump cells were injected subcutaneously (instead of intramuscularly), the number also increased to 5 × 105. When cynomolgus ES cell-derived progenitor cells (1 × 106), which included residual pluripotent cells, were transplanted into the lower limb muscle of NOG or NOD/SCID mice, the incidence of teratomas differed between the strains; teratomas developed in five of five NOG mice but in only two of five NOD/SCID mice. The incidence of teratomas varied substantially depending on the transplanted cells and recipient mice. Thus, considerable care must be taken as to tumorigenicity.
Human Transcription-Repair Coupling Factor CSB/ERCC6 Is a DNA-stimulated ATPase but Is Not a Helicase and Does Not Disrupt the Ternary Transcription Complex of Stalled RNA Polymerase II (2021)

Transcription is coupled to repair in Escherichia coli and in humans. Proteins encoded by the mfd gene in E. coli and by the ERCC6/CSB gene in humans, both of which possess the so-called helicase motifs, are required for the coupling reaction. It has been shown that the Mfd protein is an ATPase but not a helicase and accomplishes coupling, in part, by disrupting the ternary complex of E. coli RNA polymerase stalled at the site of DNA damage. In this study we overproduced the human CSB protein using the baculovirus vector and purified and characterized the recombinant protein. CSB has an ATPase activity that is stimulated strongly by DNA; however, it neither acts as a helicase nor does it dissociate stalled RNA polymerase II, suggesting a coupling mechanism in humans different from that in prokaryotes. CSB is a DNA-binding protein, and it also binds to XPA, TFIIH, and the p34 subunit of TFIIE. These interactions are likely to play a role in recruiting repair proteins to ternary complexes formed at damage sites.
Insertable biplanar gradient coils for magnetic resonance microscopy: theoretical minimization of power dissipation for different fabrication methods (2018)

High-resolution magnetic resonance microscopy (MRM) demands strong gradient magnetic fields to be driven rapidly by a set of three gradient coils. However, due to their small size, gradient coils for MRM are typically limited by resistive heating, especially since standard coil design methods for minimizing power dissipation do not account for certain fabrication constraints, which leads to suboptimal coils and low duty cycles. In this paper, a method is presented for designing insertable biplanar gradient coils that exhibit genuine minimum power dissipation, in which important geometrical parameters that define the intended fabrication method are included in the optimization. A survey of different coil types is presented and it is shown that for wire-wound coils, considerable reductions in dissipated power (21 ± 9%) and increases in efficiency (23 ± 16%) are possible compared to the corresponding standard minimum power designs.
Mechanical and Thermal Properties of Poly(<scp>L</scp>‐lactide) Incorporating Various Inorganic Fillers with Particle and Whisker Shapes (2003)

Abstract Poly( L ‐lactide) (PLLA) composites incorporating various inorganic fillers (ifR‐PLA) were prepared by the melt blending technique, and their mechanical and thermal properties were evaluated. The filler types influenced the mechanical properties of ifR‐PLA; for those incorporating particle‐ and whisker‐type fillers the tensile moduli were 3.1–3.7 and 3.7–4.5 GPa, respectively, and the flexural moduli were 4.1–4.8 and 4.8–6.1 GPa. It was found that the tensile strength and modulus, as well as the flexural modulus, of ifR‐PLA incorporating whisker‐type fillers increased in proportion to the volume percent of the fillers ( V f ). The flexural strength of ifR‐PLA incorporating 9Al 2 O 3 · 2B 2 O 3 whiskers showed a similar increase, while that of ifR‐PLA incorporating CaCO 3 whiskers showed a decrease with increasing V f . This difference may be because the 9Al 2 O 3 · 2B 2 O 3 with its large aspect ratio kept its original fibrous shape, while the CaCO 3 lost its fibrous shape during the blending process. However, the reinforcing effect of these fillers was relatively low compared with that known for the corresponding composites of the conventional polymeric materials, probably because of the poor surface adhesion of PLLA to the fillers. Comparison of effect on storage moduli of different fillers. magnified image Comparison of effect on storage moduli of different fillers.
The Palestinian Authority: the dangerous transition from failing entity to failing state<sup>*</sup> (2017)

Despite the vast resources poured by the international community into the construction of Palestinian institutions, the PA has failed to build and maintain the infrastructures required for the establishment of a vital, democratic and functioning state. By most common parameters, the PA is a failed entity. Taking into account this experience and the consequences of the last six years of Arab upheavals, characterized by the increasing phenomenon of failed states, there is a need for a paradigm shift that will increase the likelihood of a functioning Palestinian state after a peace agreement with Israel is signed and reduce the risk of its being a failed state that would pose a complex, dangerous challenge for Israel and the neighbouring Arab states.
A Study of Robotic Cooperation in Cloud Robotics: Architecture and Challenges (2018)

Networked robotics involves a collection of robots working together to perform complex tasks, such as search and rescue task in disaster management. Because such tasks are beyond the capacity of a single powerful robot, networked robotics has been widely researched. However, the modes of cooperation in traditional networked robotics have been restricted by the inherent physical constraint that all computations are performed in the robotic network, with knowledge sharing being limited to the collective storage in the network. Cloud robotics, which allows robots to benefit from the rich storage, computation, and communication resources of modern data centers, is widely accepted as a promising approach to efficient robot cooperation in applications, such as disaster management. In this paper, we study robotic cooperation in cloud robotics. We first give a conceptual view of the nature of this cooperation. We then propose three novel robotic cooperation frameworks for cloud robotics: robotic knowledge sharing cooperation, robotic physical-task cooperation, and robotic computation task cooperation. Finally, we identify several critical challenges, and illustrate the potential benefits of robotic cooperation in cloud robotics.
Zonisamide improves wearing off in Parkinson's disease without exacerbating dyskinesia: Post hoc analysis of phase 2 and phase 3 clinical trials (2021)

Zonisamide improves wearing off without exacerbating dyskinesia in Japanese patients with PD. Moreover, zonisamide 50 mg may improve dyskinesia. Further studies are needed to prospectively determine the benefits and clinical relevance of zonisamide on dyskinesia.
Semiconductor Physics: Ballistic electron transport (1986)

Electrons have been observed traversing a solid with a vacuum-like motion, without any scattering events being encountered. Since the average distance between the atoms in a solid is about 3 A, such 'ballistic' transport appears to be highly unlikely.
Experimental investigations of CPW-slotline transitions for uniplanar microwave integrated circuits (2002)

Eight novel coplanar waveguide (CPW) to slotline transitions using uniform and nonuniform CPWs or slotlines are discussed. These transitions are uniplanar and simple to fabricate. No via-holes are needed for ground connections, and integration with solid-state devices is easy. A pair of broadband transitions using CPW shorts and slotline radial stubs is demonstrated with a 1-dB bandwidth of more than 5.2:1.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Advanced laser processing of metals (1996)

Summary form only given. The application of lasers span the entire commercial and industrial scene starting from the CD player at home to welding in automobile and aircraft plants. Processes such as welding and cutting of components in order of meters, drilling dimensions of mm to /spl mu/ms are widely accepted in manufacturing. Future applications in manufacturing include: nanometer size powder generation by laser ablation; Angstrom to micron size deposition by laser CVD; mm scale coating by laser cladding; surface modification and meter scale components by direct metal deposition. The laser is a tool which can provide energy density varying from 10/sup -3/ watts/cm/sup 2/ to 10/sup 12/ watts/cm/sup 2/. They have a wavelength range varying from UV (/sup a_/193 nm) to far infrared (10.6 /spl mu/m). Recently, high brightness lasers have created new opportunities for laser processing applications. This inertialess tool of optical energy has the potential to start a new era. The preferred approach for successful process development is to apply "atomic level understanding to applications". This paper discusses the science base for many of the important laser processing techniques. Emission, absorption and laser induced fluorescence spectroscopy have been applied for studying interaction physics whereas transport models are used for quantitative understanding of the effects of process parameters on the materials. Electron optical techniques are applied to characterize the processed materials and whenever possible an effort has been made to establish structure-property-process-parameters relationship.
Assembly of Nanoscale Organic Single‐Crystal Cross‐Wire Circuits (2009)

Organic single-crystal transistors and circuits can be assembled by nanomechanical manipulation of nanowires of CuPc, F16CuPc, and SnO2:Sb. The crossed bar devices have low operational voltage, high mobility and are stable in air. They can be combined into circuits, providing varied functions including inverters and NOR and NAND logic gates, opening new opportunities for organic nanoelectronics and highly sophisticated integrated logic devices.
Carboxymethyl Cellulose/Silver Nanoparticles Composite: Synthesis, Characterization and Application as a Benign Corrosion Inhibitor for St37 Steel in 15% H<sub>2</sub>SO<sub>4</sub>Medium (2017)

This study has been designed to boost the inhibition efficiency and stability of carboxymethyl cellulose (CMC) and this objective has been achieved by incorporating silver nanoparticles (AgNPs) generated in situ by reduction of AgNO<sub>3</sub> using natural honey into CMC matrix. Characterization of CMC/AgNPs composite was done using transmission electron microscope (TEM), Fourier transform infrared (FTIR) spectroscopy, ultraviolet-visible spectroscopy (UV-vis), scanning electron microscope (SEM), and energy dispersive X-ray spectroscopy (EDS). Weight loss, electrochemical (dynamic electrochemical impedance spectroscopy, electrochemical impedance spectroscopy, and potentiodynamic polarization) supported by surface assessment (SEM, atomic force microscope, and FTIR) techniques are deployed for the anticorrosion studies of CMC/AgNPs on St37 specimen in 15% H<sub>2</sub>SO<sub>4</sub> medium. CMC/AgNPs performs better than CMC. At 25 °C, optimum inhibition efficiency of 93.94% is afforded by 1000 ppm of CMC/AgNPs from DEIS method. Inhibition efficiency of 96.37% has been achieved from weight loss method at 60 °C. CMC/AgNPs is found to retard both the anodic and cathodic reactions and the adsorption is explained using Langmuir adsorption isotherm. AFM and SEM graphics reveal smoother surface for St37 sample in the acid solution containing inhibitor than inthe solution without the inhibiting agent. FTIR and EDS results show that CMC/AgNPs molecules were adsorbed on the metal surface.