gebhart/patrepeval huggingface dataset:
Pressure Loss and Heat Transfer Through Heat Sinks Produced by Selective Laser Melting (2009)

Heat removal from electronic packages is often assisted with the use of heat sinks whose heat transfer surfaces come in a variety of forms such as cylindrical pins, flat fins, and corrugated sheet. These conventional designs are manufactured by traditional methods such as forging, machining, casting, stamping and bending, or a combination of processes. This article introduces a novel manufacturing technique, selective laser melting (SLM), and demonstrates its ability to fabricate new designs of heat sink that have not previously been considered, primarily due to their geometric complexity. Three novel finned structures have been manufactured and their thermal and fluid flow characteristics have been determined experimentally. The three heat sinks demonstrate selective laser melting's ability to produce fine detail and consist of a staggered elliptical array, an elliptical array where the pins are angled in a direction perpendicular to the flow, and a densely packed diamond array. The novel heat sink designs were compared to a cylindrical pin array manufactured using the SLM process as well as with pin fin data from the literature. The heat sinks produced by the SLM method have been shown to have superior performance to that of the conventional heat sinks. Although the angled elliptical fins transmit similar amounts of heat to the cylindrical pin fins across the range of air flow rates considered, they incur a lower pressure loss. The densely packed diamond array not only transfers 60% more heat than the cylindrical array, but does so with a lower pressure drop across it.
Echium oil is better than rapeseed oil in enriching poultry meat with<i>n</i>-3 polyunsaturated fatty acids, including eicosapentaenoic acid and docosapentaenoic acid (2008)

alpha-Linolenic acid (ALA; 18 : 3n-3) and stearidonic acid (SDA; 18 : 4n-3) are on the biosynthetic pathway of EPA (20 : 5n-3) and DHA (22 : 6n-3). The n-3 fatty acid in rapeseed oil is ALA while Echium oil contains both ALA and SDA. To determine the comparative efficacy of ALA- and SDA-rich oils in enriching broiler meat with n-3 PUFA, we offered diets supplemented with rapeseed oil (rapeseed group) or Echium oil (Echium group) for 35 d to two groups of chicks (age 21 d). There were no differences in carcass weight (2.20 (sem 0.06) v. 2.23 (sem 0.05) kg), boned, skinless thigh muscle (494 (sem 20.5) v. 507 (sem 16.7) g), boned, skinless breast muscle (553 (sem 13.4) v. 546 (sem 11.6) g) or organ weights (heart, liver and gizzard) between the two groups. The total intramuscular fat (IMF) percentage of thigh (8.0 (sem 0.64) v. 8.1 (sem 0.62) %) and breast muscles (2.3 (sem 0.24) v. 2.0 (sem 0.19) %) were also similar between the groups. In contrast, the concentrations of most of the individual n-3 fatty acids (ALA, SDA, EPA and docosapentaenoic acid) were all higher in the Echium than the rapeseed group (P < 0.05). However, differences in DHA concentrations were significant in breast but not thigh muscle IMF. The total n-3 yields/100 g serve thigh muscle were 265 and 676 mg for the rapeseed and Echium groups, respectively (P < 0.0001). The corresponding values for equivalent breast muscles were 70 and 137 mg, respectively (P < 0.01). We conclude that Echium oil is a better lipid supplement than rapeseed oil in changing the concentration and yield of n-3 fatty acids, except DHA, in broiler meat.
Abdominal fetal EKG noise removal. (1996)

Blanking is not an optimal method for maternal noise removal because of removal of some fetal QRS complex. Averaging is a viable method except in cases where the peak fetal signals are less than 75 micro Volts. Preliminary studies using an adaptive algorithm with the maternal chest EKG as reference promises to be a better solution for maternal EKG removal.
Effects of HIV Protease Inhibitor Ritonavir on Akt-Regulated Cell Proliferation in Breast Cancer (2006)

Ritonavir inhibits breast cancer growth in part by inhibiting Hsp90 substrates, including Akt. Ritonavir may be of interest for breast cancer therapeutics and its efficacy may be increased by sustained exposure or Hsp90 RNA interference.
Investigation of ESD Performance in Silicon Integrated Passive Devices (2008)

ESD failure limits have been measured in a variety of silicon integrated passive devices using the Human Body Discharge Model. The failure mechanism for these circuits is typically the destructive breakdown of the thin insulator layer in metal-insulator-metal capacitors. The capacitors in this particular technology have a static breakdown of 70 to 100V. Failure from ESD events for a single capacitor typically occurs for voltages of 200 to 300V. Tests of more complex circuits show that the ESD performance is extended by using series arrangements of capacitors. In some circuit types it is possible to use inductive shunt protection. This has been found to increase the failure voltage to above 3KV, which was the limit of the test equipment.
Subcutaneous adipocyte apoptosis in HIV-1 protease inhibitor-associated lipodystrophy (1999)

Subcutaneous adipocyte apoptosis occurs in lipoatrophic areas of patients with HIV-1 protease inhibitor-associated lipodystrophy.
An Indium Gallium Arsenide Visible/SWIR Focal Plane Array for Low Light Level Imaging (1999)

PIN photodiodes fabricated from indium gallium arsenide lattice-matched to indium phosphide substrates (In(.53)Ga(.47)As/InP) exhibit low reverse saturation current densities (JD < 10(exp -8) A/sq cm), and high shunt resistance-area products (RoA > 10(exp 6) omega-sq cm) at T=290K. Backside-illuminated, hybrid-integrated InGaAs FPAs are sensitive from 0.9 micrometers to 1.7 micrometers. 290K detectivities, D(*), greater than 10(exp 14) cm-(square root of Hz/W) are demonstrated. This represents the highest room temperature detectivity of any infrared material. The long wavelength cutoff (1.7 micrometers) makes In(.53)Ga(.47)As an idea match to the available airglow that has major peaks at 1.3 micrometers and 1.6 micrometers. The short wavelength 'cut-on' at 0.9 micrometers is due to absorption in the InP substrate. We will report on new InGaAs FPA epitaxial structures and processing techniques. These have resulted in improved performance in the form of a 10 x increase in detectivity and visible response via removal of the InP substrate. The resulting device features visible and SWIR response with greater than 15% quantum efficiency at 0.5 micrometers while maintaining the long wavelength cutoff. Imaging has been demonstrated under overcast starlight/urban glow conditions with cooling provided by a single stage thermoelectric cooler. Details on the material structure and device fabrication, quantitative characterization of spectral response and detectivity, as well as examples of night vision imagery are presented.
Big Data Analytics Embedded Smart City Architecture for Performance Enhancement through Real-Time Data Processing and Decision-Making (2017)

The concept of the smart city is widely favored, as it enhances the quality of life of urban citizens, involving multiple disciplines, that is, smart community, smart transportation, smart healthcare, smart parking, and many more. Continuous growth of the complex urban networks is significantly challenged by real-time data processing and intelligent decision-making capabilities. Therefore, in this paper, we propose a smart city framework based on Big Data analytics. The proposed framework operates on three levels: <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mo stretchy="false">(</mml:mo><mml:mn fontstyle="italic">1</mml:mn><mml:mo stretchy="false">)</mml:mo></mml:math> data generation and acquisition level collecting heterogeneous data related to city operations, <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M2"><mml:mo stretchy="false">(</mml:mo><mml:mn fontstyle="italic">2</mml:mn><mml:mo stretchy="false">)</mml:mo></mml:math> data management and processing level filtering, analyzing, and storing data to make decisions and events autonomously, and <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M3"><mml:mo stretchy="false">(</mml:mo><mml:mn fontstyle="italic">3</mml:mn><mml:mo stretchy="false">)</mml:mo></mml:math> application level initiating execution of the events corresponding to the received decisions. In order to validate the proposed architecture, we analyze a few major types of dataset based on the proposed three-level architecture. Further, we tested authentic datasets on Hadoop ecosystem to determine the threshold and the analysis shows that the proposed architecture offers useful insights into the community development authorities to improve the existing smart city architecture.
Preclinical Studies To Understand Nanoparticle Interaction with the Immune System and Its Potential Effects on Nanoparticle Biodistribution (2008)

Nanoparticles have unique physicochemical properties which make them promising platforms for drug delivery. However, immune cells in the bloodstream (such as monocytes, platelets, leukocytes, and dendritic cells) and in tissues (such as resident phagocytes) have a propensity to engulf and eliminate certain nanoparticles. A nanoparticle's interaction with plasma proteins (opsonins) and blood components (via hemolysis, thrombogenicity and complement activation) may influence uptake and clearance and hence potentially affect distribution and delivery to the intended target sites. Nanoparticle uptake by the immune cells is influenced by many factors. Different nanoparticles have been shown to act on different pathways, while various characteristics/properties also affect which pathway is employed for particle internalization. Nanoparticle protein binding occurs almost instantaneously once the particle enters biological medium, and the physical properties of such a particle-protein complex are often different than those of the formulated particle. These new properties can contribute to different biological responses and change nanoparticle biodistribution. Therefore, in the situation when specific delivery to immune cells is not desired, the ideal nanoparticle platform is the one whose integrity is not disturbed in the complex biological environment, which provides extended circulation in the blood to maximize delivery to the target site, is not toxic to blood cellular components, and is "invisible" to the immune cells which can remove it from circulation. This review discusses the most recent data on nanoparticle interactions with blood components and how particle size and surface charge define their hematocompatibility. This includes properties which determine particle interaction with plasma proteins and uptake by macrophages. We will also provide an overview of in vitro methods useful in identifying interactions with components of the immune system and the potential effects of such interaction on particle distribution to tissues.
A human-inspired controller for fluid human-robot handovers (2016)

Handovers are seamless events that occur frequently and naturally between people. Although previous works have focused on the design of robot handover controllers synthesizing one of the phases of a handover (approaching, passing, or retracting) in an isolated manner, we take a different approach and treat the handover as a single continuous entity. In this paper we present a novel bi-directional and human-inspired handover controller using insights we learned from human-human experiments. We model the dynamics of the handover in a continuous and time-independent way yielding robust and fluid behavior. We implemented our approach on a robot platform consisting of a 7-DoF robotic arm with a 16-DoF humanoid hand. Our results show that resulting humanrobot handovers are smooth and reduce internal forces with the human compared to traditional switching approaches.
Sterility in Breast Implant Placement (2011)

Plastic and Reconstructive Surgery: October 2011 - Volume 128 - Issue Supplement 4S - p 9 doi: 10.1097/01.prs.0000406217.24062.7b
Global food insecurity. Treatment of major food crops with elevated carbon dioxide or ozone under large-scale fully open-air conditions suggests recent models may have overestimated future yields (2005)

Predictions of yield for the globe's major grain and legume arable crops suggest that, with a moderate temperature increase, production may increase in the temperate zone, but decline in the tropics. In total, global food supply may show little change. This security comes from inclusion of the direct effect of rising carbon dioxide (CO2) concentration, [CO2], which significantly stimulates yield by decreasing photorespiration in C3 crops and transpiration in all crops. Evidence for a large response to [CO2] is largely based on studies made within chambers at small scales, which would be considered unacceptable for standard agronomic trials of new cultivars or agrochemicals. Yet, predictions of the globe's future food security are based on such inadequate information. Free-Air Concentration Enrichment (FACE) technology now allows investigation of the effects of rising [CO2] and ozone on field crops under fully open-air conditions at an agronomic scale. Experiments with rice, wheat, maize and soybean show smaller increases in yield than anticipated from studies in chambers. Experiments with increased ozone show large yield losses (20%), which are not accounted for in projections of global food security. These findings suggest that current projections of global food security are overoptimistic. The fertilization effect of CO2 is less than that used in many models, while rising ozone will cause large yield losses in the Northern Hemisphere. Unfortunately, FACE studies have been limited in geographical extent and interactive effects of CO2, ozone and temperature have yet to be studied. Without more extensive study of the effects of these changes at an agronomic scale in the open air, our ever-more sophisticated models will continue to have feet of clay.
Local and global feature selection for on-line signature verification (2005)

In this paper we propose a methodology for selecting the most discriminative features in a set for online signature verification. We expose the difference in the definition of class between signature verification and other pattern recognition tasks, and extend the classical Fisher ratio to make it more robust to the small sample sizes typically found when dealing with global features and client enrollment time constraints for signature verification systems. We apply our methodology to global and local features extracted from a 50-users database, and find that our criterion agrees better with classifier error rates for local features than for global features. We discuss the possibility of performing feature selection without having forgery data available.
Online controlled experiments at large scale (2013)

Web-facing companies, including Amazon, eBay, Etsy, Facebook, Google, Groupon, Intuit, LinkedIn, Microsoft, Netflix, Shop Direct, StumbleUpon, Yahoo, and Zynga use online controlled experiments to guide product development and accelerate innovation. At Microsoft's Bing, the use of controlled experiments has grown exponentially over time, with over 200 concurrent experiments now running on any given day. Running experiments at large scale requires addressing multiple challenges in three areas: cultural/organizational, engineering, and trustworthiness. On the cultural and organizational front, the larger organization needs to learn the reasons for running controlled experiments and the tradeoffs between controlled experiments and other methods of evaluating ideas. We discuss why negative experiments, which degrade the user experience short term, should be run, given the learning value and long-term benefits. On the engineering side, we architected a highly scalable system, able to handle data at massive scale: hundreds of concurrent experiments, each containing millions of users. Classical testing and debugging techniques no longer apply when there are billions of live variants of the site, so alerts are used to identify issues rather than relying on heavy up-front testing. On the trustworthiness front, we have a high occurrence of false positives that we address, and we alert experimenters to statistical interactions between experiments. The Bing Experimentation System is credited with having accelerated innovation and increased annual revenues by hundreds of millions of dollars, by allowing us to find and focus on key ideas evaluated through thousands of controlled experiments. A 1% improvement to revenue equals more than $10M annually in the US, yet many ideas impact key metrics by 1% and are not well estimated a-priori. The system has also identified many negative features that we avoided deploying, despite key stakeholders' early excitement, saving us similar large amounts.
EZH2 couples pancreatic regeneration to neoplastic progression (2012)

Although the polycomb group protein Enhancer of Zeste Homolog 2 (EZH2) is well recognized for its role as a key regulator of cell differentiation, its involvement in tissue regeneration is largely unknown. Here we show that EZH2 is up-regulated following cerulein-induced pancreatic injury and is required for tissue repair by promoting the regenerative proliferation of progenitor cells. Loss of EZH2 results in impaired pancreatic regeneration and accelerates KRas(G12D)-driven neoplasia. Our findings implicate EZH2 in constraining neoplastic progression through homeostatic mechanisms that control pancreatic regeneration and provide insights into the documented link between chronic pancreatic injury and an increased risk for pancreatic cancer.
Quantification in time-domain diffuse optical tomography using Mellin-Laplace transforms (2016)

Simulations and phantom measurements are used to evaluate the ability of time-domain diffuse optical tomography using Mellin-Laplace transforms to quantify the absorption perturbation of centimetric objects immersed at depth 1-2 cm in turbid media. We find that the estimated absorption coefficient varies almost linearly with the absorption change in the range of 0-0.15 cm<sup>-1</sup> but is underestimated by a factor that depends on the inclusion depth (~2, 3 and 6 for depths of 1.0, 1.5 and 2.0 cm respectively). For larger absorption changes, the variation is sublinear with ~20% decrease for δμ<sub>a</sub> = 0.37 cm<sup>-1</sup>. By contrast, constraining the absorption change to the actual volume of the inclusion may considerably improve the accuracy and linearity of the reconstructed absorption.
Vitiligo: Where Do We Stand? (1993)

Vitiligo is a puzzling disorder characterized by a disappearance of epidermal and/or follicular melanocytes by unknown mechanisms. This very common disorder involving 1-4% of the world population is thus of great importance for the practicing dermatologist. The cellular and molecular mechanisms leading to the destruction of melanocytes in this disorder have not yet been elucidated, making it of major interest for the cell biologist involved in melanocyte research. Recent advances in this field, due largely to the availability of techniques for culturing normal human melanocytes, opened new perspectives in the understanding of vitiligo. Although vitiligo has long been considered a disorder confined to the skin, there is now good evidence that it also involves the extracutaneous compartment of the "melanocyte organ." It is also clear that vitiligo is not only a melanocyte disorder, but that it also involves cells, such as keratinocytes and Langerhans cells, found in the epidermis and follicular epithelium. The three prevailing theories of the pathogenesis of vitiligo are the immune hypothesis, the neural hypothesis, and the self-destruct hypothesis. New hypotheses suggest that vitiligo may be due to (1) a deficiency in an unidentified melanocyte growth factor, (2) an intrinsic defect of the structure and function of the rough endoplasmic reticulum in vitiligo melanocytes, (3) abnormalities in a putative melatonin receptor on melanocytes and (4) a breakdown in free radical defense in the epidermis. None of these hypotheses has been demonstrated, and according to the available data, it is likely that the loss of epidermal and follicular melanocytes in vitiligo may be the result of several different pathogenetic mechanisms.
A method to quantify crystallinity in amorphous metal alloys: A differential scanning calorimetry study (2020)

We developed and describe a differential scanning calorimetry method for calculating the initial crystallinity, change of crystallinity and crystallinity percentage of amorphous metal alloys as a function of temperature. Using thermodynamic enthalpies of amorphous, crystalline and partially devitrified specimens, our methodology is capable of determining crystallinity percentages as low as a few percent. Moreover, the linear relationship between the set (pre-determined) and calculated crystallinities of experimental samples indicates that there is no need to prepare calibration samples before measuring the crystallinity percentage of target samples. This technique also eliminates the need for expensive in situ accessories, such as those required in electron microscopy. Thus, the technique is highly relevant as a primary technique for characterization of devitrification behavior in amorphous materials.
Detecting multiple aliases in social media (2013)

Monitoring and analysis of web forums is becoming important for intelligence analysts around the globe since terrorists and extremists are using forums for spreading propaganda and communicating with each other. Various tools for analyzing the content of forum postings and identifying aliases that need further inspection by analysts have been proposed throughout literature, but a problem related to this is that individuals can make use of several aliases. In this paper we propose a number of matching techniques for detecting forum users who make use of multiple aliases. By combining different techniques such as time profiling and stylometric analysis of messages the accuracy of recognizing users with multiple aliases increases, as shown in experiments conducted on the ICWSM dataset boards.ie.
Disability following combat-sustained nerve injury of the upper limb (2014)

Injuries to the limb are the most frequent cause of permanent disability following combat wounds. We reviewed the medical records of 450 soldiers to determine the type of upper limb nerve injuries sustained, the rate of remaining motor and sensory deficits at final follow-up, and the type of Army disability ratings granted. Of 189 soldiers with an injury of the upper limb, 70 had nerve-related trauma. There were 62 men and eight women with a mean age of 25 years (18 to 49). Disabilities due to nerve injuries were associated with loss of function, neuropathic pain or both. The mean nerve-related disability was 26% (0% to 70%), accounting for over one-half of this cohort's cumulative disability. Patients injured in an explosion had higher disability ratings than those injured by gunshot. The ulnar nerve was most commonly injured, but most disability was associated with radial nerve trauma. In terms of the final outcome, at military discharge 59 subjects (84%) experienced persistent weakness, 48 (69%) had a persistent sensory deficit and 17 (24%) experienced chronic pain from scar-related or neuropathic pain. Nerve injury was the cause of frequent and substantial disability in our cohort of wounded soldiers.