gebhart/patrepeval huggingface dataset:
Lift-off process using bilayer ultraviolet nanoimprint lithography and methacryloxypropyl-terminated-polydimethylsiloxane-based imprint resin (2009)

A high-fidelity lift-off process using bilayer ultraviolet nanoimprint lithography (UV-NIL) to fabricate nanosized metal pattern was demonstrated. High O2 reactive ion etching (RIE) selectivity of the imprinted resist pattern to the underlayer is necessary to create the undercut pattern profile that is essential for the stable lift-off process. A methacryloxypropyl-terminated polydimethylsiloxane (M-PDMS)-based UV-curable liquid-phase imprint resin and a polyvinyl alcohol (PVA) underlayer were applied to bilayer UV-NIL for the high-fidelity lift-off process. The M-PDMS-based imprinted resist pattern showed high etch resistance to O2 plasma and the undercut pattern profile of the PVA underlayer for the lift-off process was formed by the O2 RIE process. The size and shape of the imprinted resist patterns were hardly changed during PVA underlayer etching by O2 RIE. As a result, high-fidelity and high-aspect-ratio metal patterns without rabbit-ear-shaped defects were fabricated by the lift-off process using bilayer UV-NIL with the M-PDMS-based imprint resin, which has high etch resistance to O2 RIE, and the PVA underlayer.
Analysis of Knitted Fabric Structure using 3-D Voxel Data of X-ray CT Images (2005)

In this paper, a novel method for analyzing a textile fabric structure, particularly a knitted fabric one, is proposed to obtain positional information regarding the yarns of the textile fabric using voxel data made of its X-ray computed tomography (CT) images. It is possible to reconstruct the positional relationships among the yarns from the positional information. The positional information is defined as a sequence of points on the center line of each yarn of the sample in this study, since the sequence can be regarded as the representative position of the yarn and robust against measurement errors. The sequence is estimated by tracing the yarn. The yarn is traced using a three-dimensional yarn model, which is moved along the yarn direction estimated by correlating with the yarn part of the voxel data. The trajectory of the center of the yarn model corresponds to the positional information of the yarn. The effectiveness of the proposed method is discussed by experimentally applying the method to voxel data of a knitted fabric of a net stitch.
IAIMS at Columbia-Presbyterian Medical Center: accomplishments and challenges. (1992)

The concept of "one-stop information shopping" is becoming a reality at Columbia-Presbyterian Medical Center. Our goal is to provide access from a single workstation to clinical, research, and library resources; university and hospital administrative systems; and utility functions such as word processing and mail. We have created new organizational units and installed a network of workstations that can access a variety of resources and systems on any of seventy-two different host computers/servers. In November 1991, 2,600 different individuals used the clinical information system, 700 different individuals used the library resources, and 900 different individuals used hospital administrative systems via the network. Over the past four years, our efforts have cost the equivalent of $23 million or approximately 0.5% of the total medical center budget. Even small improvements in productivity and in the quality of work of individuals who use the system could justify these expenditures. The challenges we still face include the provision of additional easy-to-use applications and development of equitable methods for financial support.
The Effect of Bacterial Environmental and Metabolic Stresses on a Laser-Induced Breakdown Spectroscopy (LIBS) Based Identification of <i>Escherichia Coli</i> and <i>Streptococcus Viridans</i> (2011)

In this paper we investigate the effect that adverse environmental and metabolic stresses have on the laser-induced breakdown spectroscopy (LIBS) identification of bacterial specimens. Single-pulse LIBS spectra were acquired from a non-pathogenic strain of Escherichia coli cultured in two different nutrient media: a trypticase soy agar and a MacConkey agar with a 0.01% concentration of deoxycholate. A chemometric discriminant function analysis showed that the LIBS spectra acquired from bacteria grown in these two media were indistinguishable and easily discriminated from spectra acquired from two other non-pathogenic E. coli strains. LIBS spectra were obtained from specimens of a nonpathogenic E. coli strain and an avirulent derivative of the pathogen Streptococcus viridans in three different metabolic situations: live bacteria reproducing in the log-phase, bacteria inactivated on an abiotic surface by exposure to bactericidal ultraviolet irradiation, and bacteria killed via autoclaving. All bacteria were correctly identified regardless of their metabolic state. This successful identification suggests the possibility of testing specimens that have been rendered safe for handling prior to LIBS identification. This would greatly enhance personnel safety and lower the cost of a LIBS-based diagnostic test. LIBS spectra were obtained from pathogenic and non-pathogenic bacteria that were deprived of nutrition for a period of time ranging from one day to nine days by deposition on an abiotic surface at room temperature. All specimens were successfully classified by species regardless of the duration of nutrient deprivation.
Design and Implementation of Low Power FMCW Radar System (2018)

In view of the short range of FMCW radar, a S band FMCW coherent radar system is designed with Mini-Circults Series RF devices as the core. The production mode and signal processing mode of FM signal are improved. Compared with the traditional radar system, this design has the advantages of low cost, good maintenance, and large room for improvemengood maintenance, and large room for improvement.t.
Sweet Candies, Amiable Spring Festival (2013)

In the memory of every Chinese,the Spring Festival deposits abundant beauties:a lively scene with lanterns and streamers,an endless parade of delicious food,or a little toy of childhood memories.When I was a child,I visited a Sugar Painting Exhibition at Beihai Park in Beijing.I was amazed by the exquisitely made flowers and birds,and charmingly nave animals;and every kid was totally captured by a huge solid dragon settling in the central exhibition hall.Truly,that winter deeply impressed me with the vivid sugar dragon and the fragrance
Growth of InGaAsSb layers in the miscibility gap: Use of very-low-energy ion irradiation to reduce alloy decomposition (1995)

Thin (∼0.2–0.5 μm), quaternary InxGa1−xAsySb1−y alloy films with compositions across the solid-phase miscibility gap were grown using ion-assisted deposition (IAD) on Si(001) and InP(001) substrates. The IAD chamber was designed to provide very-low-energy (≤30 eV), high flux (∼0.4 mA/cm2) Ar ion irradiation of the film surface during growth. Under conditions where ion irradiation effects were negligible, broadened x-ray diffraction peaks and increased surface roughness as a function of the proximity of the alloy composition to the center of the miscibility gap was observed. High-resolution cross-sectional transmission electron microscopy analysis of films, deposited nearly lattice matched on InP substrates, showed decomposition into columns elongated in the growth direction when the alloy composition was within the miscibility gap. A composition modulation wavelength of ∼7 nm was measured parallel to the film surface. The role of ion irradiation in suppressing decomposition in InGaAsSb alloy thin films deposited within the miscibility gap was investigated. Ar+ ion irradiation with a flux of ∼3×1015 cm2 s−1, and energy of 19–21 eV was found to improve both the homogeneity and electron mobility of the alloy films. This was attributed to the suppression of composition modulations by collisional mixing of the film surface during growth. Ar+ ion energies above 21 eV resulted in excessive structural damage to the films.
Distributed Server Delivery of Immersive VoIP Service: Balancing Between Voice Latency and Access Upload Cost (2007)

As a future communication tool to the distributed virtual environment, the Immersive VoIP service delivers to each user a real-time mix of nearby user voices which are all rendered according to their respective virtual world positions. In this work, we conjecture that the voice latency constraints between Immersive VoIP users would vary according to their virtual world distance of separation. As verified in our subjective listening tests, this conjecture is more realistic than fixed latency constraint, in terms of user perceptual experience and network feasibility. Empowered by the Bandwidth Reduced server assignment algorithm, the proposed two-hop distributed server architecture achieves a better balance between access bandwidth cost and voice latency when compared against the central server and the peer-to-peer architectures. The two-hop architecture targets the challenging scenario where there lacks clear correlations between the virtual world and the underlying physical network. In addition, we have also investigated the necessary frequency to execute the server assignment solutions to mitigate sensitivity to virtual world mobility.
Processing-in-memory: A workload-driven perspective (2019)

Many modern and emerging applications must process increasingly large volumes of data. Unfortunately, prevalent computing paradigms are not designed to efficiently handle such large-scale data: The energy and performance costs to move this data between the memory subsystem and the CPU now dominate the total costs of computation. This forces system architects and designers to fundamentally rethink how to design computers. Processing-in-memory (PIM) is a computing paradigm that avoids most data movement costs by bringing computation to the data. New opportunities in modern memory systems are enabling architectures that can perform varying degrees of processing inside the memory subsystem. However, many practical system-level issues must be tackled to construct PIM architectures, including enabling workloads and programmers to easily take advantage of PIM. This article examines three key domains of work toward the practical construction and widespread adoption of PIM architectures. First, we describe our work on systematically identifying opportunities for PIM in real applications and quantify potential gains for popular emerging applications (e.g., machine learning, data analytics, genome analysis). Second, we aim to solve several key issues in programming these applications for PIM architectures. Third, we describe challenges that remain for the widespread adoption of PIM.
Structure-activity relationships of analogs of pentamidine against Plasmodium falciparum and Leishmania mexicana amazonensis. (2020)

The antiprotozoal compound 1,5-di(4-amidinophenoxy)pentane (pentamidine) and 36 of its analogs were screened for in vitro activity against Leishmania mexicana amazonensis clone 669 C4S (MHOM/BR/73/M2269) and Plasmodium falciparum clones W2 (Indochina III/CDC) and D6 (Sierra Leone I/CDC). Pentamidine and each of the analogs tested exhibited activity in vitro against L. m. amazonensis and P. falciparum. The pentamidine analogs were more effective against the P. falciparum clones than against L. m. amazonensis. P. falciparum was extremely susceptible to these compounds, with 50% inhibitory concentrations as low as 0.03 microM. While none of the analogs exhibited marked improvement in antileishmanial activity compared with pentamidine, 12 of the pentamidine analogs showed activity approximately equal to or greater than that of the parent compound. From the promising activity exhibited by the pentamidine analogs in this in vitro study and their potential for reduced toxicity relative to the parent drug, pentamidine-related compounds hold promise as new agents for the treatment of protozoal infections.
Distal Charge Transport in Peptides (2007)

Biological systems often transport charges and reactive processes over substantial distances. Traditional models of chemical kinetics generally do not describe such extreme distal processes. In this Review, an atomistic model for a distal transport of information, which was specifically developed for peptides, is considered. Chemical reactivity is taken as the result of distal effects based on two-step bifunctional kinetics involving unique, very rapid motional properties of peptides in the subpicosecond regime. The bifunctional model suggests highly efficient transport of charge and reactivity in an isolated peptide over a substantial distance; conversely, a very low efficiency in a water environment was found. The model suggests ultrafast transport of charge and reactivity over substantial molecular distances in a peptide environment. Many such domains can be active in a protein.
Seismic Isolation Systems for Developing Countries (2002)

This paper describes an experimental and theoretical study of the feasibility of using fiber reinforcement to produce lightweight low‐cost elastomeric isolators for application to housing, schools and other public buildings in highly seismic areas of the developing world. The theoretical analysis covers the mechanical characteristics of multi‐layer elastomeric isolation bearings where the reinforcing elements, normally steel plates, are replaced by a fiber reinforcement. The fiber in the fiber‐reinforced isolator, in contrast to the steel in the conventional isolator (which is assumed to be rigid both in extension and flexure), is assumed to be flexible in extension, but completely without flexure rigidity. This leads to an extension of the theoretical analysis on which the design of steel‐reinforced isolators is which accommodates the stretching of the fiber‐reinforcement. Several examples of isolators in the form of long strips were tested at the Earthquake Engineering Research Center Laboratory. The tested isolators had significantly large shape factors, large enough that for conventional isolators the effects of material compressibility would need to be included. The theoretical analysis is extended to include compressibility and the competing influences of reinforcement flexibility and compressibility are studied. The theoretical analysis suggests and the test results confirm that it is possible to produce a fiber‐reinforced strip isolator that matches the behavior of a steel‐reinforced isolator. The fiber‐reinforced isolator is significantly lighter and can be made by a much less labor‐intensive manufacturing process. The advantage of the strip isolator is that it can be easily used in buildings with masonry walls. The intention of this research is to provide a low‐cost lightweight isolation system for housing and public buildings in developing countries.
A gene-targeted approach to investigate the intestinal butyrate-producing bacterialcommunity (2013)

The presented approach provides quantitative and genotypic insights into butyrate-producing communities and facilitates a more specific functional characterization of the intestinal microbiome. Furthermore, our analysis refines but and buk reference annotations found in central databases.
Anti-inflammatory Effects of the Extract of Rubus scuaivissimus Cultivated in Guangxi (2010)

OBJECTIVE: To investigate the anti-inflammatory effects of the extract of Rubus scuaivissimus cultivated in Guangxi. METHODS: The inhibition effects of the extract of R. scuaivissimus on vasopermeability and acute mice ear swelling induced by croton oil, and mice paw swelling induced by carrageenan were observed. The content of nitric oxide (NO) and the mRNA expression of iNOS in mice peritoneal macrophages were detected using Griess and RT-PCR assay. RESULTS: The extract of R. scuaivissimus cultivated in Guangxi can conspicuously inhibit the increase of vasopermeability and acute ear swelling induced by croton oil in mice,and mice paw swelling induced by carrageenan. Furthermore, R. scuaivissimus extract also showed depressant effect on the release of NO and genes expression of iNOS mRNA in mouse peritoneal macrophages. CONCLUSION: The extract of R. scuaivissimus cultivated in Guangxi has conspicuous anti-inflammatory effects. The mechanism of action may be associated with its inhibition effects on the release of NO and mRNA expression of iNOS.
Different Models of Wind Speed Prediction; A Comprehensive Review (2014)

Abstract — The energy crisis witnessed in the early seventies is a serious problem that had happened in the universe. Hence, induction of renewable energy into electrical power generation mix can serve as an alternative source to cater for the limited reserve of fossil fuels. Wind energy is promising and has emerged as one of the safest, cleanest and fastest growing renewable energy in the recent years. The bottleneck of this type of emission free energy is the variability, stochastic, unpredictable and complex nature of the wind speed. To harness the energy content in a wind efficiently, it’s of utmost importance to accurately predict wind speed and energy with minimum accepted errors for security and economics of wind power utilization. For this reason, it becomes necessary to appraise different types of models used in the wind energy forecast. This paper present review of available wind speeds and power prediction models and discuss their applications and current developments. Moreover, the survey also highlights an overview strength and weakness of these models.
Field efficacy of imidacloprid and <i>Steinernema carpocapsae</i> in a chitosan formulation against the red palm weevil <i>Rhynchophorus ferrugineus</i> (Coleoptera: Curculionidae) in <i>Phoenix canariensis</i> (2009)

Both imidacloprid and S. carpocapsae in a chitosan formulation proved highly effective against R. ferrugineus in the field, and their efficacies did not significantly change when used in combination.
A Sensitive, Specific Immunobioassay for Quantitation of Human Interleukin 6 (1993)

Picogram quantities of human interleukin 6 (h-IL-6) were detected by a two-step method. A microtiter plate coated with anti-h IL-6 monoclonal antibody was used to capture the IL-6 present in biological samples. An IL-6- dependent B cell line (7TD1) that proliferates in response to IL-6 was added to the captured IL-6. The lower limit of detection for this immunobioassay with serum or cell culture supernatants was 5 pg/ml. The specificity of the assay was achieved by the antibody used in the first step. The sensitivity was provided by the IL-6-dependent cell line. The method also allows for the removal of inhibitors, metabolites, antagonists or activating agents used to induce IL-6. This immunobioassay has the advantage over other current methods in that it measures immunoactive as well as biologically active IL-6.
Close-packed cell arrays for dish concentrators (2002)

The two main components of the system under development are: (1) PV modules with close-packed cells for "stacking" into fully active receivers of any scale; and (2) parabolic dish concentrator system with supports and interface. The advantages of such a system are outlined for GaAs and Si receivers. The system requirements and performance are discussed.
Synthesis of sulfur-containing macrocycles using cesium thiolates (1981)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of sulfur-containing macrocycles using cesium thiolatesJ. Buter and Richard M. KelloggCite this: J. Org. Chem. 1981, 46, 22, 4481–4485Publication Date (Print):October 1, 1981Publication History Published online1 May 2002Published inissue 1 October 1981https://pubs.acs.org/doi/10.1021/jo00335a032https://doi.org/10.1021/jo00335a032research-articleACS PublicationsRequest reuse permissionsArticle Views785Altmetric-Citations142LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Luteolin sensitizes the anticancer effect of cisplatin via c-Jun NH2-terminal kinase–mediated p53 phosphorylation and stabilization (2007)

Luteolin is an important flavonoid with a potential anticancer effect. In this study, we examined the molecular mechanisms involved in the sensitization effect of luteolin on cancer cell killing induced by cisplatin, an important cancer chemotherapeutic agent. First, we provided evidence that the sensitization effect of luteolin on cisplatin-induced apoptosis is p53 dependent, as such effect is only found in p53 wild-type cancer cells but not in p53 mutant cancer cells. Moreover, knockdown of p53 by small interfering RNA made p53 wild-type cancer cells resistant to luteolin and cisplatin. Second, we observed a significant increase of p53 protein level in luteolin-treated cancer cells without increase of p53 mRNA level, indicating the possible effect of luteolin on p53 posttranscriptional regulation. Third, we identified the critical role of c-Jun NH(2)-terminal kinase (JNK) in regulation of p53 protein stability: luteolin activates JNK, and JNK then stabilizes p53 via phosphorylation, leading to reduced ubiquitination and proteasomal degradation. Finally, by using an in vivo nude mice xenograft model, we confirmed that luteolin enhanced the cancer therapeutic activity of cisplatin via p53 stabilization and accumulation. In summary, data from this study reveal a novel molecular mechanism involved in the anticancer effect of luteolin and support its potential clinical application as a chemosensitizer in cancer therapy.