gebhart/patrepeval huggingface dataset:
A "CAT" family of repetitive DNA sequences in Saccharomyces cerevisiae. (1986)

An oligonucleotide probe was used to isolate yeast genomic clones containing DNA sequences with repetitive elements consisting primarily of a tandemly arranged trinucleotide, CAT. Hybridization analyses estimate that the yeast genome contains 40-50 CAT clusters, representing the first repetitive DNA sequence family found in yeast. Sequence analyses show short spacers between the CAT repeats consisting of closely related trinucleotides, primarily CGT. Some of the CAT clusters are located in longer repeating elements with lengths of 7 nucleotides or more. In one case a three-times-repeated 27-nucleotide sequence bears striking homology to the 21-base pair repeat region of the mammalian simian virus 40 promoter element. Hybridization studies further suggest that the "CAT" sequences may be widely dispersed in many diverse organisms including Escherichia coli, Drosophila, and man.
Light-intensity distribution in eccentric photorefraction crescents (1998)

We try to improve the accuracy of eccentric photorefraction by taking more information into account than just the size and tilt of the crescent. Based on Gaussian optics and the assumption of an isotropic scattering retina, a theoretical analysis of the light-intensity distribution in the pupils of astigmatic eyes is presented. The method is applied to different photorefractor setups (point light source, long linear light source, knife-edge aperture, and circular aperture). In the case of a knife-edge aperture the crescent structure can be formulated analytically. In the case of a circular aperture an analytic description is possible only for spherical refractive errors, but astigmatic refractive errors can be determined from crescent parameters with neural networks.
Detection of Sub-Clinical CWD Infection in Conventional Test-Negative Deer Long after Oral Exposure to Urine and Feces from CWD+ Deer (2009)

Detection of subclinical infection in deer orally exposed to urine and feces (1) suggests that a prolonged subclinical state can exist, necessitating observation periods in excess of two years to detect CWD infection, and (2) illustrates the sensitive and specific application of sPMCA in the diagnosis of low-level prion infection. Based on these results, it is possible that low doses of prions, e.g. following oral exposure to urine and saliva of CWD-infected deer, bypass significant amplification in the LRS, perhaps utilizing a neural conduit between the alimentary tract and CNS, as has been demonstrated in some other prion diseases.
A framework for the parallel processing of Datalog queries (1990)

This paper presents several complementary methods for the parallel, bottom-up evaluation of Datalog queries. We introduce the notion of a discriminating predicate, based on hash functions, that partitions the computation between the processors in order to achieve parallelism. A parallelization scheme with the property of non-redundant computation (no duplication of computation by processors) is then studied in detail. The mapping of Datalog programs onto a network of processors, such that the results is a non-redundant computation, is also studied. The methods reported in this paper clearly demonstrate the trade-offs between redundancy and interprocessor-communication for this class of problems.
A simple method for generating facial barcodes (2014)

In this paper we propose a simple method for generating standard type linear barcodes from facial images. The\nmethod uses the difference in gradients of image brightness. It involves averaging the gradients into a limited\nnumber of intervals, quantization of the results into the range of decimal numbers from 0 to 9, and table\nconversion into the final barcode. The proposed solution is computationally low-cost and does not require the\nuse of any specialized image processing software, which makes it possible to generate facial barcodes in mobile\nsystems. Results of tests conducted on the Face94 database and a database of composite faces at different ages\nshow that the proposed method is a new solution for use in real-world practice. It ensures the stability of the\ngenerated barcodes against changes of scale, pose and mirroring of facial images, as well as changes of facial\nexpressions and shadows on faces from local lighting.
Effective Vehicle-Based Kangaroo Detection for Collision Warning Systems Using Region-Based Convolutional Networks (2018)

Traffic collisions between kangaroos and motorists are on the rise on Australian roads. According to a recent report, it was estimated that there were more than 20,000 kangaroo vehicle collisions that occurred only during the year 2015 in Australia. In this work, we are proposing a vehicle-based framework for kangaroo detection in urban and highway traffic environment that could be used for collision warning systems. Our proposed framework is based on region-based convolutional neural networks (RCNN). Given the scarcity of labeled data of kangaroos in traffic environments, we utilized our state-of-the-art data generation pipeline to generate 17,000 synthetic depth images of traffic scenes with kangaroo instances annotated in them. We trained our proposed RCNN-based framework on a subset of the generated synthetic depth images dataset. The proposed framework achieved a higher average precision (AP) score of 92% over all the testing synthetic depth image datasets. We compared our proposed framework against other baseline approaches and we outperformed it with more than 37% in AP score over all the testing datasets. Additionally, we evaluated the generalization performance of the proposed framework on real live data and we achieved a resilient detection accuracy without any further fine-tuning of our proposed RCNN-based framework.
Ticagrelor-Induced Prolongation of the QTc Interval (2019)

We present a case of ticagrelor-induced QTc prolongation. To our knowledge, this is the first case to be reported on the same. The Naranjo algorithm for causality assessment gave a total score of 6 indicating that the adverse drug reaction falls under the <i>probable</i> category.
A New Technique for Obtaining Bone Graft in Cases of Distal Femur Nonunion: Passing a Reamer/Irrigator/Aspirator Retrograde Through the Nonunion Site. (2017)

Bone grafting is one of the most common orthopedic procedures. We conducted a study to assess the possibility of passing a Reamer/Irrigator/Aspirator (RIA; DePuy Synthes) retrograde through the nonunion site in distal femur cases. This technique would avoid the complications and discomfort associated with a separate entry site for RIA. All patients with a distal femur nonunion treated with RIA bone grafting between 2009 and 2013 were included in the study. Nonunions were mobilized with excision of fibrous tissues. The distal part was angulated into varus, and then the guide wire was passed from the nonunion site laterally. Five patients had a RIA passed retrograde through the nonunion site. Mean age of these patients was 40.4 years (range, 22-66 years). Mean reamer size was 13.4 mm (mode, 14 mm), producing an average bone graft volume of 33 mL. There were no intraoperative or postoperative fractures. In 1 case, the reamer shaft broke. Passing a RIA retrograde through the nonunion site in distal femur cases is reproducible, and the technique avoids the discomfort and pain associated with a separate entry point as well as the complication of eccentric reaming of the proximal and distal part of the femoral canal.
Ideas (1980)

The IDEAS this month provide practice for addition, subtraction, multiplication and division of rational numbers.
Randomized controlled trial to test the effect of on- arrival vaccination and deworming on Stocker cattle health and growth performance (2018)

Our objective was to determine the effect of vaccination and deworming at arrival (d 0) on bovine respiratory disease (BRD) incidence, mortality, and growth of stocker calves. Calves (n=80) were stratified by d -3 weight and fecal egg count (FEC) into 20 pens of 4 calves. Pens were randomly assigned to treatments in a 2×2 factorial design, testing d 0 vaccination (modified-live respiratory virus and clostridial vaccine, or not) and deworming (oral fenbendazole and levamisole, or not). Body weights were measured on days 0, 14, 28, 42, 56, 70, and 85, and FEC were measured on days -3, 28, 56, and 85. Incidence of BRD was greater for d 0 vaccination (RR=3.2), high fever (≥104°F, ≥40°C) at d 0 (RR=6), and higher d -3 FEC (RR=1.2 per 100 epg). Mortality was greater for d 0 vaccination (OR=8.3) and high fever (OR=41.6). Growth was 10.3 lb (4.7 kg) lower for d 0 vaccination, 24 lb (11 kg) and 16 lb (7.3 kg) lower for moderate (103°F to 103.9°F; 39.4°C to 39.9°C) and high fever, respectively, and 17.6 lb (8 kg) lower for each additional BRD treatment a calf received. Deworming was neither beneficial nor detrimental to any health or performance factors. Health and growth performance of stocker calves may be adversely affected by vaccination at arrival, higher arrival FEC, and fever at arrival.
Complete suppression of filamentation and superior beam quality in quantum-dot lasers (2003)

Comparative near-field and beam-quality (M2) measurements on narrow stripe quantum-dot (QD) and quantum-well (QW) lasers of identical structure, both emitting at 1100 nm, are presented. Intrinsic suppression of filamentation in the QD lasers is observed. QD lasers emitting at 1300 nm again show no filamentation. For a 6-μm-stripe, QW laser, M2 increases from 2.6 to 6.1 with output power increasing from 5 to 60 mW and with increasing stripe width (20 mW, 3→10 μm, M2=2.6→4.7). In the QD lasers, filamentation is suppressed up to 8 μm (1100 nm) and 9 μm (1300 nm) stripe width and no dependence on output power is observed.
Mass Media Usage by Rural Youth in Agriculture in Udham Singh Nagar District of Uttarakhand (2017)

Harnessing demographic dividend has become the greatest challenge before India which has aroused the demand for skilled youth especially in agriculture sector. Information technology has revolutionized Indian agriculture by opening door of enormous opportunities by playing a crucial role in scientific farming. Communication can help in motivating youthto take agriculture as a vocation by giving them right and customized information timely and location specific. The present study investigated communication behaviour of rural youth in Udham Singh Nagar District of Uttarakhand state, India. Data was collected through stratified random sampling with proportionate allocation for selecting 120 respondents for the study area. The study revealed that majority of respondents had medium level mass media exposure. Television was used mostly for entertainment, political and agricultural purpose in their own homes at night time. Majority of them were found satisfied with the information shown in the television via different agricultural programs and therefore inclined towards accepting that information. Mass media usage had a significant and positive relationship with education, innovativeness, achievement motivation, leadership ability and cosmopoliteness.The analysis of qualitative data indicated youth keenness to use information through mass media. The present study recommended that mass media infrastructure should be encouraged and utilized by rural youth in the rural areas to facilitate customized information delivery in a right time.
Inductively Coupled Plasma Mass Spectrometry as a Simple, Rapid, and Inexpensive Method for Determination of Uranium in Urine and Fresh Water (1996)

A simple method, based on inductively coupled plasma mass spectrometry, for determination of uranium in urine at levels that indicate occupational exposure, is presented. Sample preparation involves a fifty-fold dilution of the urine by nitric acid (2% HNO3) and no other chemical treatment or separation. The analysis itself is completed in under 3 min. The analytical procedure is fully automated so that a technician may perform over 100 analyses per day. With proper control of the blank contribution, a lower limit of detection of 3 ng L(-1) in the original urine sample was achieved. Uranium concentrations in the range 6-30 ng L(-1) were found in urine samples of people that are not occupationally exposed. The validity of the results was demonstrated through measurement of standards, controlled uranium addition experiments and, at higher concentrations, by comparison with results obtained by an independent method based on laser induced fluorescence. The laser induced fluorescence technique was found to be sufficient for detection of occupational exposure at an action level of 1.5 microg L(-1). Use of internal standards, indium, and thallium, improved quantification by about 10%, but was not deemed necessary for routine analysis. The inductively coupled plasma mass spectrometry is also ideally suited for monitoring uranium in fresh water and drinking water, as no sample dilution is required and the lower limit of detection is below 0.15 ng L(-1).
Multiple tissue kallikrein mRNA and protein expression in normal skin and skin diseases (2005)

Human tissue kallikreins are a gene family (KLK1-KLK15) encoding for 15 secretory serine proteases (hK1-hK15). Two tissue kallikrein proteins, hK5 and hK7, were previously found in the stratum corneum (SC), stratum granulosum (SG) and appendages. hK8 was also shown to be secreted via lamellar granules and numerous KLK mRNAs were previously identified. KLKs are believed to be responsible for desquamation of corneocytes and sebum, sweat and hair maturation.To demonstrate immunohistochemically the expression of hK6, hK8 and hK13 in normal skin tissue and to show an increased cell number expressing kallikrein mRNAs and proteins in psoriasis vulgaris (PV) and atopic dermatitis (AD).Samples of normal, PV and AD skin were obtained. hK6-, hK8- and hK13-specific antibodies were produced and used for immunohistochemical analysis. Multiple KLK mRNAs were synthesized and used for in situ hybridization study.Three other hKs, namely hK6, hK8 and hK13, were immunohistochemically identified as new skin serine proteases in the whole SC, SG, sebaceous glands, eccrine sweat glands, hair follicles and nerves. We also demonstrated an increased number of cells expressing KLK mRNAs and hKs in PV and AD. In PV, KLK mRNAs/hKs were predominantly expressed in the upper epidermis. In AD, hK distribution was rather diffuse and expanded into the lower epidermis.The colocalization of various hKs seems to be essential for the regulation of serine protease activity in skin and for steady desquamation and skin barrier function. Moreover, the increased number of cells expressing multiple KLK mRNA and hK in PV and AD could be a clue to elucidate their pathogenesis.
Market Orientation: The Implementation of the Marketing Concept (2001)

The marketing literature has provided little guidance in relation to creating market driven organisations. It has traditionally provided pieces of the puzzle i.e. the product life cycle, segmentation etc, but it has fallen short of demonstrating how to put the pieces together to complete the picture i.e. creating a market oriented organisation. As a result marketing has largely been confined to ‘overseeing and co-ordinating activities directly involved with the outside - such as sales, promotion and delivery’ (Witcher B J, 1990). This has led to a situation where many organisations have reservations about the success achieved with the implementation of the marketing concept.
Estimating software size with UML models (2008)

Function points have been used for more than 25 years for estimating software size and building productivity models. Today, three methods to do it are accepted as ISO standards. The theory behind this type of measurement is more explicit but none of these methods have yet been fully automated. All of them still require the involvement of an expert in order to be used correctly. Why is it so difficult to implement those methods? In our opinion, the main reason lies in the fact that each method has its own vocabulary and its own way of modeling software. The research work presented here has been realised mainly through two doctoral theses, one trying to automate the measure from a UML perspective and the other to add an objective measure of complexity to a standard measure in COSMIC-FFP in order to reach a higher level of confidence with those measures. So far, it can be concluded that, from UML use-cases and Actor-Object sequence diagrams of a system application, the number of messages exchanged correspond to the number of function points according to the COSMIC-FFP method. Going farther and adding the number of conditions or decisions to be applied according to UML version 2.0 would add more precision taking into account the complexity of the processes.
A new tool for accurate S-parameters measurements and permittivity reconstruction (2005)

In this paper, we present a tool for permittivity reconstruction. The tool consists of a coaxial transmission line and a novel analytical reconstruction technique. The line is designed for accurate permittivity measurements of soil samples. It allows for single or double phase flow. The full S-parameter matrix is modeled with transmission line theory. We show that for accurate measurements each component of the tool needs careful calibration. We give a method to compute the sensitivity of these measurements to different materials, and we show the accuracy in the determination of the sample permittivity from the measurements based on deviations of the forward model compared to measured results as a function of the error in the sample permittivity. We demonstrate that a maximum error of less than 1% is obtained for the possible permittivity reconstruction from these measurements for wavelengths less than five times the sample holder length. The novel reconstruction technique is based in the propagation matrices method. It consists in rewriting the transmission line model in matrix notation and relating the S-parameters to the total reflection and transmission of the line seen as a two-port network. Thanks to this novel approach, the reconstruction of both permittivity and permeability can be done directly from the measured S-parameters of the line. Due to experimental instabilities the errors are considerable, and we must restrict ourselves to the reconstruction of permittivity. Results on an air sample are within the predicted error of 1%. Computing relative errors for an ethanol sample is not possible due to temperature and purity difference between our experiment and published results; nevertheless, the reconstructed permittivity of ethanol follows the Debye model.
Rapid evolution and the cost of resistance to<i>Bacillus thuringiensis</i>in greenhouse populations of cabbage loopers,<i>Trichoplusia ni</i> (2003)

The microbial insecticide Bacillus thuringiensis (Bt) has become the mainstay of non-chemical control of Lepidopteran pests, either as sprays or through the incorporation of Bt toxins into transgenic crops. Given the wide use of Bt, it is striking that currently only one pest species, Plutella xylostella, has been reported to have developed significant resistance to Bt outside the laboratory. By contrast, we report here the frequent and rapid development of resistance to B. thuringiensis kurstaki (Dipel, Abbott) in populations of cabbage loopers, Trichoplusia ni, in commercial greenhouses. Resistance to Bt appears to be costly and there is a rapid decline of resistance in populations collected from greenhouses and maintained in the laboratory without selection. Management of pests resistant to Bt in vegetable greenhouses will require sporadic use of Bt-based sprays or alternatively use of sprays containing other Bt toxins.
Optical coupling efficiency of bidirectional transceiver sub-module with refractive index control (2003)

Conventionally, optical communication modules for subscriber have been composed of transmitter and receiver as separated or combined requiring two lines of optical fibers to constitute a network. To realize the fiber-to-the-home (FTTH), it is necessary to make the cheaper and more compact module as well as to reduce the fiber installation cost. In this study, an accurate silicon optical bench (SiOB) has been designed for passive integration of bidirectional transceiver sub-module. Optical coupling between the transceiver chip and a single mode fiber is accomplished by aligning an acute angle-faceted fiber on the V-groove of SiOB to the front facet of the flip-chip bonded chip. Transmitted light from the laser diode of the transceiver chip is coupled into fiber core as in usual buff coupling, while receiving light from the fiber is refracted downward by Snell's law and absorbed into pin-PD's photosensitive area after being reflected at the metal coated V-groove side-wall.
Melody Extraction By Contour Classification. (2015)

[TODO] Add abstract here.
Adaptable infrastructure for future scalable flexible and resilient optical networks (2012)

A new flexible networking infrastructure able to provide on-demand services and functionalities is proposed. The benefits of the proposed approach in terms of scalability, resiliency and the flexibility to provide various levels of bandwidth virtualisation and arbitrary topology implementation are discussed in the paper. © 2012 SEE.
Integration of multi-layer perceptron and Markov models for automatic speech recognition (1990)

The paper presents the implementation of a new speech recognition system based on the integration of three semi-independent blocks: the acoustic processor (AP), which converts the speech signal into a set of robust acoustic features: the multi-layer perceptron (MLP) that maps the acoustic feature sequences to phonemes, discriminating the spectral variation from the real phonetic information; and the hidden Markov model (HMM), which produces a final identification of the entire utterance as consequence of the computations of the probabilistic phonetic observations output by the MLP. >
A Versatile Approach Towards Nucleobase‐Modified Aptamers (2015)

A novel and versatile method has been developed for modular expansion of the chemical space of nucleic acid libraries, thus enabling the generation of nucleobase-modified aptamers with unprecedented recognition properties. Reintroduction of the modification after enzymatic replication gives broad access to many chemical modifications. This wide applicability, which is not limited to a single modification, will rapidly advance the application of in vitro selection approaches beyond what is currently feasible and enable the generation of aptamers to many targets that have so far not been addressable.
Single-Photon Interference in Sidebands of Phase-Modulated Light for Quantum Cryptography (1999)

We report single-photon interference in the sidebands of modulated light. The relative phase of interacting quantum states is reliably controlled by the phase of a low-frequency modulating signal. We show how this type of interference can be used to build a robust system for quantum cryptography. An experiment was implemented at 1540 nm, over a 20-km-long standard single-mode fiber, using a germanium singlephoton avalanche photodiode.