gebhart/patrepeval huggingface dataset:
Topical application of marine briarane-type diterpenes effectively inhibits 12-O-tetradecanoylphorbol-13-acetate-induced inflammation and dermatitis in murine skin (2011)

Our results suggest that BrDs warrant further investigation as natural immunomodulatory agents for control of inflammatory skin diseases.
An investigation of block-adaptive decision feedback equalization for frequency selective fading channels (2003)

Block adaptation techniques are investigated by computer simulation for decision feedback equalization on a rapidly fading dispersive channel. Tradeoffs between training sequence length and block length are found. Block adaptation, supplemented by linear interpolation of coefficients, is found to be an attractive alternative to more complex continuously adapting recursive least squares adaptation algorithms.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Comparison of the micro‐ and macro‐vascular effects of glimepiride and gliclazide in metformin‐treated patients with Type 2 diabetes: a double‐blind, crossover study (2003)

There is no evidence that SUR1-specific and nonspecific SUs have differential effects on arterial distensibility, endothelial function or vasodilator mechanisms in metformin-treated patients with T2DM.
F-Doped NaTi<sub>2</sub>(PO<sub>4</sub>)<sub>3</sub>/C Nanocomposite as a High-Performance Anode for Sodium-Ion Batteries (2018)

We are presenting a sol-gel method for building novel nanostructures made of nanosized F-doped Na<sub>1-2 x</sub>Ti<sub>2</sub>(PO<sub>4</sub>)<sub>3- x</sub>F <sub>x</sub> (NTP-F <sub>x</sub>, x = 0, 0.02, 0.05, and 0.10) particles embedded in three-dimensional (3D) carbon matrices (NTP-F <sub>x</sub>/C). This technique combines advantages of both zero-dimensional materials and 3D-carbon networks. Proper fluorine doping stabilizes the NTP structure and greatly enhances ion/electron transportation, leading to superhigh-rate electrochemical performance and ultralong cycle life. The composite electrode delivers high specific capacities of 121, 115, 112.2, 110.1, 107.7, 103.1, 85.8, and 62.5 mA h g<sup>-1</sup> at 0.2, 0.5, 1, 2, 5, 10, 20, and 30 C, respectively. It retains an unbelievable ∼70% capacity after a thousand cycles at a rate as high as 10 C. Electroanalytical results reveal that fluorine doping significantly enhances Na<sup>+</sup> diffusion kinetics. Meanwhile, density functional theory calculations demonstrate F-doped NTPs' own outstanding electrochemical properties, which is due to the enhanced intrinsic ionic/electronic conductivity. The results show that anion doping is an efficient way to make high-performance NTP anodes for sodium-ion batteries.
A tetramethylbenzidine/tungstate reaction for horseradish peroxidase histochemistry. (1991)

Tracing of neuroanatomical pathways commonly involves the histochemical demonstration of horseradish peroxidase, using the chromogen tetramethylbenzidine. A new modification of this reaction using ammonium paratungstate stabilizer retains high sensitivity while permitting the reaction to be performed at pH 6.0 in isotonic solutions. The reaction product resists solvents, allowing Nissl-stained sections to retain their peroxidase labeling. With subsequent stabilization by diaminobenzidine, the tissue is suitable for electron microscopic study and is compatible with post-embedding immunocytochemistry.
Design and implementation of full-bridge driver for carbon nanotube field emission lamp (2009)

A high voltage full-bridge resonant inverter is proposed for driving carbon nanotube field emission lamp (CNTL). First, we construct an equivalent model of CNTL to exhibit its electric characteristics. Moreover, the high frequency sinusoidal driving strategy is employed to eliminate the arcing phenomenon caused by the traditional DC driving. And then the PLL feedback controller is used to stabilize the lamp luminance. Complete design considerations and mathematical model are detailed. All the experimental results agree with the theoretical predictions.
iOS based speed estimation for the video car recorder system (2013)

Recently, APPs (applications for intelligent mobile devices) about car recorder systems have been proposed for various mobile OS. Due to the numbers of APPs in the iOS is more than that of others OS, our car video recorder system is built on iOS. In addition, the objective-c programming language is employed to code APPs in the Xcode. Usually, the iOS mobile devices (e.g. iPhone) are equipped with GPS and camera. Hence, we only need to design software on the integration and links so as to replace the traditional tachograph. Basically, the intelligent mobile device has three types of positioning methods: built-in GPS, telecommunication base-station triangulation positioning method and Wi-Fi base-station positioning method. Although the user's position can be quickly located, it can not provide an accurately location for user when the positioning signal are hardly received. Besides, the speed data provided by the positioning methods may easily be affected by disturbances. It should be noted that iPhone usually cannot provide an accurate car's speed. In this study, a corrected speed method for the intelligent video car recorder is proposed. In the corrected speed method, the car speed in iPhone is corrected by the linear regression method. In our experience, the proposed method can improve the accuracy of the car speed estimation in iPhone.
Inhibitory Effect of <i>Carthamus tinctorius</i> L. Seed Extracts on Bone Resorption Mediated by Tyrosine Kinase, COX-2 (cyclooxygenase) and PG (prostaglandin) E<sub>2</sub> (2002)

Anti-bone resorption properties of the Korean herbal formulation, Honghwain (HHI; Carthamus tinctorius L. seed) was biochemically investigated. On processing bone metabolism, PGE2 accelerated production of IL-1beta in fetal mouse osteoblast and stimulated physiological activation substance, IL-1beta. The novel class of Src tyrosine kinase inhibitors, Herbimycin A (HERB) and HHI reduced COX-2 mRNA levels as well as PGE2 production induced by IL-1beta, TNF-alpha and IL-6. HHI inhibited in vitro and in vivo bone resorption by inhibition of phosphorylation of peptide substrates. HHI dose-dependently reduced the hypercalcemia induced in mice by IL-1beta and partly prevented bone loss and microarchitectural changes in young ovariectomized rats, showing that the protective effect on bone was exerted via the inhibition of bone resorption. These results indicate that the synergy between IL-beta, TNF-alpha, IL-6 on PGE2 production is due to an enhanced gene expression of COX-2 and that tyrosine kinase (s) are involved in the signal transduction of COX-2 in mouse calvarial osteoblasts. Thus, HHI as a possible Src family kinase inhibitor may be useful for the treatment of diseases associated with elevated bone loss.
Comparison of surgical resection versus transarterial chemoembolization with additional radiation therapy in patients with hepatocellular carcinoma with portal vein invasion (2018)

Surgical resection might be an effective treatment in HCC patients with PVI.
Neutralization of activity of effector protein by monoclonal antibody: formulation of antibody dose-dependence of neutralization for an equilibrium system of antibody, effector, and its cellular receptor. (1985)

Binding of an antibody to an effector protein will not necessarily inactivate it totally. In order to incorporate this into mathematical expressions of neutralization reaction between a monoclonal antibody and an effector which acts on cells through receptor binding, a static equilibrium system was considered that consists of effector, receptor and antibody, allowing formation of the ternary complex. A formula was derived for the antibody dose-dependence of neutralization, which was qualitatively similar to that found experimentally for monoclonal antibodies to interferon. According to the formula, the extent of neutralization, N, will approach a saturation value N infinity at high antibody concentrations, instead of increasing indefinitely, as is the case with conventional antibodies; the value N infinity is determined by the degree of reduction, upon antibody binding, of the effector's affinity to the receptor (and/or by the ability of antibody to inhibit the effector action subsequent to receptor binding). On the other hand, experimental data in the region of small N's will allow one to estimate the effector-antibody association constant.
Molecular and functional characterization of a cDNA encoding fructan:fructan 6G-fructosyltransferase (6G-FFT)/fructan:fructan 1-fructosyltransferase (1-FFT) from perennial ryegrass (Lolium perenne L.) (2006)

Fructans are the main storage compound in Lolium perenne. To account for the prevailing neokestose-based fructan synthesis in this species, a cDNA library of L. perenne was screened by using the onion (Allium cepa) fructan:fructan 6G-fructosyltransferase (6G-FFT) as a probe. A full length Lp6G-FFT clone was isolated with significant homologies to vacuolar type fructosyltransferases and invertases. The functionality of the cDNA was tested by heterologous expression in Pichia pastoris. The recombinant protein demonstrated both 6G-FFT and fructan:fructan 1-fructosyltransferase activities (1-FFT) with a maximum 6G-FFT/1-FFT ratio of two. The activity of 6G-FFT was investigated with respect to developmental stage, tissue distribution, and alterations in carbohydrate status expression and compared to sucrose:sucrose 1-fructosyltransferase (1-SST). Lp6G-FFT and Lp1-SST were predominantly expressed in the basal part of elongating leaves and leaf sheaths. Expression of both genes declined along the leaf axis, in parallel with the spatial occurrence of fructan and fructosyltransferase activities. Surprisingly, Lp6G-FFT was highly expressed in photosynthetically active tissues where very low extractable fructosyltransferase activity and fructan amounts were detected, suggesting a post-transcriptional regulation of expression. Lp6G-FFT gene expression increased only in elongating leaves following similar increases of sucrose content in blades, sheaths, and elongating leaf bases. Regulation of Lp6G-FFT gene expression depends on the tissue according to its sink-source status.
A power-saving technique for bit-serial DSP ASICs (2002)

The bit-serial processing technique arises to be a competitor of the traditional bit-parallel processing technique to implement DSP ASICs, because the bit-serial implementation of DSP ASICs usually results in small communication cost and compact processing elements. However, shift registers are usually used to realize delays required by the DSP algorithms. Long shift registers consume a lot of power for they are clocked at very high frequency. More troublesome is that the power associated with driving a lot of clocked transistors has to be supplied by the clock lines (not power supply lines), which may cause clock distribution problem. In this paper, we propose a power-saving technique without speed penalty by getting rid of unnecessary data shifting and long shift registers. All the delay elements in the traditional long shift registers are realized by DRAM-alike memory cells and data is not shifted but accessed by using shared cyclical address decoders. The measurement of a test chip indicates a power saving by 4 times when we need to use 15 16-bit shift registers. More power saving is expected when we need more shift registers for large DSP ASICs.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Reduction of speed ripple and vibration for switched reluctance motor drive via intelligent current profiling (2010)

This study presents the speed ripple and vibration reductions for a switch-mode rectifier (SMR) fed switched reluctance motor (SRM) drive via intelligent current profiling approach. Firstly, the SRM drive with a boost-type SMR front-end is established, which possesses well-regulated DC-link voltage and good AC line drawn power quality. Secondly, the speed ripple generating process of a SRM is explored. Accordingly, a robust and intelligent speed ripple reduction approach is proposed, wherein the leading edge of winding current command is modified by adding a compensating component, which is automatically generated from the DC-link negative stroke spikes caused by non-ideal commutation. Thirdly, a robust current error cancellation control scheme is designed to yield closer current waveform tracking response, and thus the smoother motor developed torque. In outer loop, a robust speed ripple cancellation control scheme is employed to directly reduce the speed ripple. Finally, the commutation shift is applied to further improve the torque sharing characteristics between phases during commutation period and thus reduce the speed ripple and vibration. In addition, the commutation shift also leads to the improved torque per ampere capability of a SRM. Validity of all the proposed control approaches is demonstrated experimentally.
The Saccharomyces cerevisiae RPB4 gene is tightly linked to the TIF2 gene (1991)

A S. cerevisiae genomic expression library, constructed in Xgtl 1 (1), was screened using polyclonal antibodies raised against poly(A) polymerase isolated from rat hepatoma cells (2). The 3.8 kb insert from clone XAS109 obtained by this procedure was sequenced in its entirety. One long open reading frame (ORF) and portions of two other ORFs were identified. The partial ORFs were found to correspond to the genes encoding translation initiation factor eIF-4A (TIF2) (3) and the fourth largest subunit of RNA polymerase II (RPB4) (4). The other ORF, designated YUR1, did not resemble any other sequences in the swiss-protein, EMBL, or genbank databases. Figure The nucleotide sequence of the region between TIF2 and RPB4 has been assigned accession number X58099.
Iodine/Iodide-Free Dye-Sensitized Solar Cells (2009)

Dye-sensitized solar cells (DSSCs) are built from nanocrystalline anatase TiO(2) with a 101 crystal face (nc-TiO(2)) onto which a dye is absorbed, ruthenium complex sensitizers, fluid I(-)/I(3)(-) redox couples with electrolytes, and a Pt-coated counter electrode. DSSCs have now reached efficiencies as high as 11%, and G24 Innovation (Cardiff, U.K.) is currently manufacturing them for commercial use. These devices offer several distinct advantages. On the basis of the electron lifetime and diffusion coefficient in the nc-TiO(2) layer, DSSCs maintain a diffusion length on the order of several micrometers when the dyed-nc-TiO(2) porous layer is covered by redox electrolytes of lithium and/or imidazolium iodide and their polyiodide salts. The fluid iodide/iodine (I(-)/I(3)(-)) redox electrolytes can infiltrate deep inside the intertwined nc-TiO(2) layers, promoting the mobility of the nc-TiO(2) layers and serving as a hole-transport material of DSSCs. As a result, these materials eventually give a respectable photovoltaic performance. On the other hand, fluid I(-)/I(3)(-) redox shuttles have certain disadvantages: reduced performance control and long-term stability and incompatibility with some metallic component materials. The I(-)/I(3)(-) redox shuttle shows a significant loss in short circuit current density and a slight loss in open circuit voltage, particularly in highly viscous electrolyte-based DSSC systems. Iodine can also act as an oxidizing agent, corroding metals, such as the grid metal Ag and the Pt mediator on the cathode, especially in the presence of water and oxygen. In addition, the electrolytes (I(-)/I(3)(-)) can absorb visible light (lambda = approximately 430 nm), leading to photocurrent loss in the DSSC. Therefore, the introduction of iodide/iodine-free electrolytes or hole-transport materials (HTMs) could lead to cost-effective alternatives to TiO(2) DSSCs. In this Account, we discuss the iodide/iodine-free redox couple as a substitute for the fluid I(-)/I(3)(-) redox shuttle. We also review the adaptation of solid-state HTMs to the iodide/iodine-free solid-state DSSCs with an emphasis on their pore filling and charge mobility in devices and the relationship of those values to the performance of the resulting iodide/iodine-free DSSCs. We demonstrate how the structures of the sensitizing dye molecules and additives of lithium or imidazolium salts influence device performance. In addition, the self-organizing molecular interaction for electronic contact of HTMs to dye molecules plays an important role in unidirectional charge diffusion at interfaces. The poly(3,4-ethylenedioxythiophene) (PEDOT)-based DSSCs, which we obtain through photoelectrochemical polymerization (PEP) using 3-alkylthiophen-bearing ruthenium dye, HRS-1, and bis-EDOT, demonstrates the importance of nonbonding interface contact (e.g., pi-pi-stacking) for the successful inclusion of HTMs.
Weakly secure data exchange with Generalized Reed Solomon codes (2014)

We focus on secure data exchange among a group of wireless clients. The clients exchange data by broadcasting linear combinations of packets over a lossless channel. The data exchange is performed in the presence of an eavesdropper who has access to the channel and can obtain all transmitted data. Our goal is to develop a weakly secure coding scheme that prevents the eavesdropper from being able to decode any of the original packets held by the clients. We present a randomized algorithm based on Generalized Reed-Solomon (GRS) codes. The algorithm has two key advantages over the previous solutions: it operates over a small (polynomial-size) finite field and provides a way to verify that constructed code is feasible. In contrast, the previous approaches require exponential field size and do not provide an efficient (polynomial-time) algorithm to verify the secrecy properties of the constructed code. We formulate an algebraic-geometric conjecture that implies the correctness of our algorithm and prove its validity for special cases. Our simulation results indicate that the algorithm is efficient in practical settings.
Two Novel Genes in the Center of the 11p15 Imprinted Domain Escape Genomic Imprinting (1999)

We previously reported the isolation of a 2.5 Mb tumor-suppressing subchromosomal transferable fragment (STF) from human chromosome 11p15 and the identification of nine known genes and four novel genes within this STF. We now report the isolation of two novel cDNAs, designated here as TSSC4 and TSSC6 (tumor-suppressing STF cDNA 4 and 6), located within the STF. TSSC4 and TSSC6 encode predicted proteins of 329 and 290 amino acids, respectively, with no close similarity to previously reported proteins. TSSC4 and TSSC6 are both located in the center of a 1 Mb imprinted domain, which contains the imprinted genes TSSC3, TSSC5, p57(KIP2), KVLQT1, ASCL2, IGF2 and H19. However, we found that neither TSSC4 nor TSSC6 was significantly imprinted in any of the fetal or extra-embryonic tissues examined. Based on this result, the imprinted gene domain of 11p15 appears to contain at least two imprinted subdomains, between which TSSC4 and TSSC6 substantially escape imprinting, due either to lack of initial silencing or to an early developmental relaxation of imprinting.
TRANSDISCIPLINARIEDAD SIN FRONTERAS EN LA PRÁCTICA Y LA DOCENCIA DE LA ESCENOGRAFÍA. CREACIÓN DE ESPACIOS ESCENOGRÁFICOS (2022)

El presente artículo analiza ciertas prácticas artísticas transdisciplinares en la producción de escenografías, teniendo en cuenta la relevancia de lo procesual dentro del ámbito de la creación artística. Para ello se toma como estudio de caso la docencia de la asignatura “Escenografía” en la Facultad de Bellas Artes de la Universidad de Málaga. Esta asignatura enmarcada en el área de Escultura intenta cuestionar el proceso de creación artística de un espacio escenográfico facilitando una formación activa y manteniendo unas propuestas que desarrollen el espíritu investigador y experimental tanto a nivel formal como conceptual del alumnado, partiendo de la obra literaria “Historias de cronopios y famas” de Julio Cortázar. El planteamiento de esta asignatura busca generar un espacio formativo que motive la investigación y creatividad del alumnado y promueva la búsqueda de nuevas alternativas expresivas y simbólicas en el diseño y creación de espacios escenográficos
Dual-Layer Dielectric Stack for Thermally Isolated Low-Energy Phase-Change Memory (2017)

High reset energy is an ongoing issue for phase-change memory (PCM) devices. Prior work demonstrates that smaller PCM switching volume and thermal isolation can reduce the reset energy. In this paper, we fabricate and measure a planar confined PCM device with a multilayer dual-layer stack (D'S) of SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> /Al <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> insulator. Devices with contact area of 500 × 20 nm and lengths of 2 μm show exceptionally low reset energies of 18.25 ± 15.8 pJ and low reset current densities of 0.94 ± 0.51 MA/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . Implementing the D'S enables a 60% reduction in reset energy compared with SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> -isolated devices.
Bacteria-Phage Antagonistic Coevolution in Soil (2011)

Bacteria and their viruses (phages) undergo rapid coevolution in test tubes, but the relevance to natural environments is unclear. By using a "mark-recapture" approach, we showed rapid coevolution of bacteria and phages in a soil community. Unlike coevolution in vitro, which is characterized by increases in infectivity and resistance through time (arms race dynamics), coevolution in soil resulted in hosts more resistant to their contemporary than past and future parasites (fluctuating selection dynamics). Fluctuating selection dynamics, which can potentially continue indefinitely, can be explained by fitness costs constraining the evolution of high levels of resistance in soil. These results suggest that rapid coevolution between bacteria and phage is likely to play a key role in structuring natural microbial communities.
Characterization of Chemical Constituents of &lt;i&gt;Luffa operculata&lt;/i&gt;(Cucurbitaceae) (2011)

A mixture of new ceramides (1, 2, 3, 4 and 5) together with a binary mixture of ceramides with long chain alkyl (6 and 7), triterpenoid (10) and steroids (11 and 12) have been isolated from bark of the fruits and of the stems of Luffa operculata (Cucurbitaceae). The structures were elucidated by comprehensive spectro- scopic analysis including 1H and 13C NMR, DEPT (distortionless enhancement by polarization transfer), COSY (correlated spectroscopy), HMQC (heteronuclear multiple quantum coherence), HMBC (heteronu- clear multiple bond connectivity), IR (infrared), HR-ESI-MS (electrospray ionization-high resolution mass spectra) and LR-MS (low resolution electron ionization mass spectra) experiments. All the ceramides are reported for the first time in Cucurbitaceae and this is the first report of the rare triterpene 10 isolated from Luffa operculata. The ceramides 6 and 7 showed a high acetylcholine esterase inhibitory effect.
Optical CoMP Transmission in Millimeter-Wave Small Cells for Mobile Fronthaul (2014)

We propose and experimentally demonstrate a prototype of local centralized optical coordinated multipoint (CoMP) that targets beamforming applications in future-proof millimeter-wave small cells based on radio-over-fiber fronthauls.