gebhart/patrepeval huggingface dataset:
Mechanisms and Products of Surface-Mediated Reductive Dehalogenation of Carbon Tetrachloride by Fe(II) on Goethite (2004)

Natural attenuation processes of chlorinated solvents in soils and groundwaters are increasingly considered as options to manage contaminated sites. Under anoxic conditions, reactions with ferrous iron sorbed at iron(hyro)xides may dominate the overall transformation of carbon tetrachloride (CCl4) and other chlorinated aliphatic hydrocarbons. We investigated mechanisms and product formation of CCl4 reduction by Fe(II) sorbed to goethite, which may lead to completely dehalogenated products or to chloroform (CHCl3), a toxic product which is fairly persistent under anoxic conditions. A simultaneous transfer of two electrons and cleavage of two C-Cl bonds of CCl4 would completely circumvent chloroform production. To distinguish between initial one- or two-bond cleavage, 13C-isotope fractionation of CCl4 was studied for reactions with Fe(II)/ goethite (isotopic enrichment factor epsilon = -26.5% percent per thousand) and with model systems for one C-Cl bond cleavage and either single-electron transfer (Fe(II) porphyrin, epsilon = -26.1 percent per thousand) or partial two-electron transfer (polysulfide, epsilon = -22.2 percent per thousand). These epsilon values differ significantlyfrom calculations for simultaneous cleavage of two C-Cl bonds (epsilon approximately equal to -50 percent per thousand), indicating that only one C-Cl bond is broken in the critical first step of the reaction. At pH 7, reduction of CCl4 by Fe(II)/ goethite produced approximately 33% CHCl3, 20% carbon monoxide (CO), and up to 40% formate (HCOO-). Addition of 2-propanol-d8 resulted in 33% CDCl3 and only 4% CO, indicating that both products were generated from trichloromethyl radicals (*CCl3), chloroform by reaction with hydrogen radical donors and CO by an alternative pathway likely to involve surface-bound intermediates. Hydrolysis of CO to HCOO-was surface-catalyzed by goethite butwastoo slow to account for the measured formate concentrations. Chloroform yields slightly increased with pH at constant Fe(II) sorption density, suggesting that pH-dependent surface processes direct product branching ratios. Surface-stabilized intermediates may thus facilitate abiotic mineralization of CCl4, whereas the presence of H radical donors, such as natural organic matter, enhances formation of toxic CHCl3.
Generation of laser-induced cavitation bubbles with a digital hologram (2008)

We demonstrate a method using a spatial light modulator (SLM) to generate arbitrary 2-D spatial configurations of laser induced cavitation bubbles. The SLM acts as a phase hologram that controls the light distribution in the focal plane of a microscope objective. We generate cavitation bubbles over an area of 380 x 380 microm(2) with a 20x microscope objective through absorption of the pulsed laser light in a liquid ink solution. We demonstrate the ability to accurately position up to 34 micrometer sized bubbles using laser energies of 56 microJ.
Regulation of macrophage activation in alcoholic liver disease (2007)

Chronic ethanol feeding sensitizes Kupffer cells to activation by lipopolysaccharide (LPS), leading to increased production of tumor necrosis factor alpha (TNFalpha). The regulation of TNFalpha synthesis is controlled by both transcriptional and post-transcriptional mechanisms via the integration of complex signal transduction pathways activated in response to LPS exposure. Recent data has shown that increased LPS-stimulated phosphorylation of extracellular signal-regulated kinase pathway 1/2 (ERK1/2) is one of the important molecular targets of chronic ethanol in Kupffer cells. This increased activation of ERK1/2 after chronic ethanol is associated with increased expression of Egr-1, a transcription factor required for enhanced LPS-stimulated TNFalpha mRNA expression after chronic ethanol exposure. egr-1 null mice are protected from the development of fatty liver injury in response to chronic ethanol feeding, identifying an essential role for Egr-1 in the development of chronic ethanol-induced liver injury. Here we review recent studies aimed at understanding the mechanisms by which chronic ethanol enhances the LPS-->ERK1/2-->Egr-1-->TNFalpha pathway in Kupffer cells. These studies identify a critical role for nicotinamide adenine dinucleotide phosphate (NADPH) oxidase-derived reactive oxygen species in the activation of ERK1/2 and subsequent production of TNFalpha in Kupffer cells after chronic ethanol feeding.
Organizacja i funkcjonowanie podziemnego wymiaru sprawiedliwości na Wileńszczyźnie w latach II wojny światowej (1940-1945) (2010)

Sulechów
Study of LDMOS-SCR: A high voltage ESD protection device (2010)

A novel LDMOS-SCR device for electrostatic discharge protection of power device is presented. The device is able to be fabricated in SOI 40V LDMOS process without any extra mask. Due to the new structure, a proper and controllable triggering voltage and fine heat dissipation capability are achieved.
On the Origin of Optical Activity in Tris-diamine Complexes of Co(III) and Rh(III):  A Simple Model Based on Time-Dependent Density Function Theory (2004)

Time-dependent density functional theory (TD-DFT) is applied to the CD spectra of Lambda(deltadeltadelta)-(+)-[Co(S-pn)n(en)(3-n)]3+ (n = 1, 2, 3) and Lambda(deltadeltadelta)-(+)-[Co(en)3]3+ as well as the stereoisomers Delta-((delta)n(lambda)(3-n))-(-)-[Co(S-pn)n(en)(3-n)]3+ (n = 1, 2, 3) and Delta(deltadeltadelta)-(-)-[Co(en)3]3+. Theory is able to reproduce the major differences in the CD spectra of the species with a Lambda-configuration and their isomers with a Delta-configuration in both the d-d and ligand-to-metal CT region. It is further possible to rationalize the trend in terms of a larger azimuthal distortion away from the octahedral geometry in the Lambda-conformation compared to the Delta-configuration. Considerations were also given to the CD spectra of the lel3-isomer, Delta(lambdalambdalambda)-(-)-[Rh(R-pn)3]3+ and the ob-isomer, Lambda(lambdalambdalambda)-(+)-[Rh(S-pn)3]3+.
RTP Payload Format for G.719 (2009)

This document specifies the payload format for packetization of the
G.719 full-band codec encoded audio signals into the Real-time
Transport Protocol (RTP). The payload format supports transmission of
multiple channels, multiple frames per payload, and interleaving.
An Age- and State-Dependent Nonlinear Prognostic Model for Degrading Systems (2015)

Nonlinearity and stochasticity are two important factors contributing to the degradation processes of complicated systems, and thus have to be taken into account in stochastic degradation modeling based prognostics. However, current studies almost always focus on age-dependent stochastic degradation models, most of which are linear, or can be transformed into linear models. In this paper, we propose a general age- and state-dependent nonlinear degradation model for prognostics. In the presented model, a diffusion process with age- and state-dependent nonlinear drift and volatility coefficients is utilized to characterize the dynamics and nonlinearity of the degradation progression. To derive the estimated remaining useful life distribution, the considered diffusion process is first converted into a diffusion process with age- or state-dependent nonlinear drift but constant volatility through Lamperti transformation. Then, based on a well-known time-space transformation, we obtain an analytical approximated remaining useful life distribution in the concept of the first passage time. Furthermore, a maximum likelihood estimation method for unknown parameters in the concerned model is presented on the basis of closed-form approximated degradation state transition density functions by the Hermite-expansion method. An illustrative example is provided to show how the obtained results can be applied to a specific age- and state-dependent nonlinear degradation model. Finally, the presented model is fitted to bearing degradation data. Comparative results suggest the necessity of age- and state-dependent nonlinear degradation modeling in prognostics.
Insights into Closeness of Relationship as Determinant of Trust Within Marketing Channels (1999)

Abstract This article explores the role of closeness of relationship between channel members. Closeness is put forward as a genuine variable in channel relationships, as part of the processes that take place in marketing channel dyad interactions. Advances in theory of channel relationships are proposed by a deeper theoretical development of the concept “closeness of relationship” from a multidisciplinary approach by stressing its relevance and by proposing a definition of closeness of relationship. Several features and ideas about closeness are proposed, such as the link between closeness of relationship and type of marketing relationship. Content validity is assessed to distinguish closeness from related constructs before exploring and operationalizing such a concept. The relationship between closeness and trust is explored by proposing actions to increase trust and assessing it empirically. An exploratory research is performed in the Spanish computer sector, testing relationships between a set of closeness components and trust between channel members. Results show that there are two factors underlying the construct closeness: interdependence and communication. However, only communication variables are significantly related to trust. Several conclusions and research propositions relevant for marketing theory and practice are presented.
Comparable Performance Measurement System for Construction Companies (2007)

The construction industry has mainly relied on financially focused performance measurements, and studies on performance measurement systems (PMSs) have been carried out at the project level. However, recently, the demand for performance evaluation and management at the company level has increased. A few previous efforts have aimed to develop a conceptual framework for company performance, but there have been few follow-up studies. From this perspective, we have developed an implementation model and practical methodology to measure and compare the performance of construction companies. First, our thorough qualitative and quantitative analysis was used to develop a set of indicators for performance measurement, and an analysis of the relative weightings of the indicators was carried out. Second, we calculated the performance score of construction companies using a study of 34 Korean construction companies. Finally, we carried out a performance evaluation and system analysis using the calculated performance scores and identified practical issues for the implementation of our PMS. Using the results of our analytical processes identified in this work, further research is suggested.
Reduced Graphene Oxide Wrapped FeS Nanocomposite for Lithium-Ion Battery Anode with Improved Performance (2013)

A new nanocomposite formulation of the FeS-based anode for lithium-ion batteries is proposed, where FeS nanoparticles wrapped in reduced graphene oxide (RGO) are produced via a facile direct-precipitation approach. The resulting nanocomposite FeS@RGO structure has better lithium ion storage properties, exceeding those of FeS prepared without RGO sheets. The enhanced electrochemical performance is attributed to the robust sheet-wrapped structure with smaller FeS nanoparticles and synergetic effects between FeS and RGO sheets, such as increased conductivity, shortened lithium ion diffusion path, and the effective prevention of polysulfide dissolution.
Shelf Stability of Isocyanate‐Functionalized Vinyl Acrylic Latexes (2009)

Abstract Copolymerization of vinyl acetate (VA) with butyl acrylate (BA) and dimethyl meta‐isopropenyl benzyl isocyanate (TMI) was carried out at 40 °C in emulsions stabilized with sodium dodecyl sulfate (SDS) or sodium dodecyl benzene sulfonate (SDBS). Regardless of the type of surfactant employed, latexes were very unstable during storage. Moreover, the hydrolysis of TMI and undesirable premature crosslinking of the polymeric chains did occur at room temperature during latexes storage.
Administration of Recombinant Interleukin-12 to Mice Suppresses Hematopoiesis in the Bone Marrow but Enhances Hematopoiesis in the Spleen (1995)

Although IL-12 has been reported to synergize with c-kit ligand (KL) in promoting hematopoietic stem cell proliferation in vitro, administration of recombinant mouse IL-12 (rIL-12) to normal mice caused a dose- and time-dependent anemia, leukopenia, and thrombocytopenia in vivo. Decreased numbers of bone marrow cells were recovered from the tibiae of IL-12-treated mice, and histologic examination of the marrow revealed a loss of mature neutrophils and red blood cell precursors. However, simultaneously with the suppression of hematopoiesis in the bone marrow, the IL-12-treated mice developed splenomegaly, which was largely caused by a marked enhancement of splenic extramedullary hematopoiesis of the erythroid, myeloid, and megakaryocytic lineages. These histologic observations were confirmed by colony-forming cell assays in which administration of IL-12 was shown to cause a time-dependent decrease in bone marrow CFU-GM, CFU-E, and BFU-E hematopoietic colony-forming cells while causing an increase in splenic CFU-GM and BFU-E colony-forming cells. All these effects were reversible upon cessation of IL-12 treatment. The observation that in IL-12-treated mice hematopoiesis was suppressed in the marrow but enhanced in the spleen suggests that myelosuppression was not caused by a direct effect of IL-12 on hematopoietic progenitors. It seems likely that myelosuppression was caused instead by an IL-12-induced alteration in the local environment of the marrow.
Transferring the Rig and Animations from a Character to Different Face Models (2008)

Abstract We introduce a facial deformation system that allows artists to define and customize a facial rig and later apply the same rig to different face models. The method uses a set of landmarks that define specific facial features and deforms the rig anthropometrically. We find the correspondence of the main attributes of a source rig, transfer them to different three‐demensional (3D) face models and automatically generate a sophisticated facial rig. The method is general and can be used with any type of rig configuration. We show how the landmarks, combined with other deformation methods, can adapt different influence objects (NURBS surfaces, polygon surfaces, lattice) and skeletons from a source rig to individual face models, allowing high quality geometric or physically‐based animations. We describe how it is possible to deform the source facial rig, apply the same deformation parameters to different face models and obtain unique expressions. We enable reusing of existing animation scripts and show how shapes nicely mix one with the other in different face models. We describe how our method can easily be integrated in an animation pipeline. We end with the results of tests done with major film and game companies to show the strength of our proposal.
The TCP Bandwidth-Delay Product revisited: network buffering, cross traffic, and socket buffer auto-sizing (2003)

TCP is often blamed that it cannot use efficiently network paths with high Bandwidth-Delay Product (BDP). The BDP is of fundamental importance because it determines the required socket buffer size for maximum throughput. In this paper, we re-examine the BDP concept, considering the effects of network buffering and cross traffic on the `bandwidth&apos; and `delay&apos; characteristics of a path. We show that, with careful socket buffer sizing, a bulk TCP transfer can saturate a network path independent of the BDP or the available network buffers. In a non-congested path, there is a certain socket buffer size (which depends on the cross traffic type) that maximizes the throughput of a bulk TCP transfer. In a congested path, the TCP throughput is maximized when the connection is limited by the congestion window, rather than by the socket buffers. Finally, we present an application-layer mechanism (SOBAS) that automatically adjusts the socket buffer size close to its optimal value, based on direct measurements of the maximum received throughput and of the round-trip time, without requiring prior knowledge of the path characteristics.
Use of antisense oligonucleotides for selective inhibition of gene expression in cardiomyocytes (1996)

peer reviewed
A 106-kDa Aminopeptidase Is a Putative Receptor for <i>Bacillus thuringiensis</i> Cry11Ba Toxin in the Mosquito <i>Anopheles gambiae</i> (2008)

Bacillus thuringiensis (Bt) insecticidal toxins bind to receptors on midgut epithelial cells of susceptible insects, and binding triggers biochemical events that lead to insect mortality. Recently, a 100-kDa aminopeptidase N (APN) was isolated from brush border membrane vesicles (BBMV) of Anopheles quadrimaculatus and shown to bind Cry11Ba toxin with surface plasmon resonance (SPR) detection [Abdullah et al. (2006) BMC Biochem. 7, 16]. In our study, a 106-kDa APN, called AgAPN2, released by phosphatidylinositol-specific phospholipase C (PI-PLC) from Anopheles gambiae BBMV was extracted by Cry11Ba bound to beads. The AgAPN2 cDNA was cloned, and analysis of the predicted AgAPN2 protein revealed a zinc-binding motif (HEIAH), three potential N-glycosylation sites, and a predicted glycosylphosphatidylinositol (GPI) anchor site. Immunohistochemistry localized AgAPN2 to the microvilli of the posterior midgut. A 70-kDa fragment of the 106-kDa APN was expressed in Escherichia coli. When purified, it competitively displaced 125I-Cry11Ba binding to An. gambiae BBMV and bound Cry11Ba on dot blot and microtiter plate binding assays with a calculated K d of 6.4 nM. Notably, this truncated peptide inhibited Cry11Ba toxicity to An. gambiae larvae. These results are evidence that the 106-kDa GPI-anchored APN is a specific binding protein, and a putative midgut receptor, for Bt Cry11Ba toxin.
Using support vector machines for long-term discharge prediction (2006)

Abstract Accurate time- and site-specific forecasts of streamflow and reservoir inflow are important in effective hydropower reservoir management and scheduling. Traditionally, autoregressive moving-average (ARMA) models have been used in modelling water resource time series as a standard representation of stochastic time series. Recently, artificial neural network (ANN) approaches have been proven to be efficient when applied to hydrological prediction. In this paper, the support vector machine (SVM) is presented as a promising method for hydrological prediction. Over-fitting and local optimal solution are unlikely to occur with SVM, which implements the structural risk minimization principle rather than the empirical risk minimization principle. In order to identify appropriate parameters of the SVM prediction model, a shuffled complex evolution algorithm is performed through exponential transformation. The SVM prediction model is tested using the long-term observations of discharges of monthly river flow discharges in the Manwan Hydropower Scheme. Through the comparison of its performance with those of the ARMA and ANN models, it is demonstrated that SVM is a very potential candidate for the prediction of long-term discharges.
Improved Grid Security Posture through Multi-factor Authentication (2011)

While methods of securing communication over the Internet have changed from clear text to secure encrypted channels over the last decade, the basic username-password combination for authentication has remained the mainstay in academic research computing and grid environments. Security incidents affecting grids, such as the TeraGrid stakkato incident of 2004 and 2005, has demonstrated that the use of reusable passwords for authentication can be readily exploited and can lead to a widespread security incident across the grid [1, 2]. The University of Tennessee's National Institute for Computational Sciences (NICS) founded in 2008 has provided resources to the TeraGrid, including Kraken, a 1.17 petaflops Cray XT5, and has implemented and promoted the use of multi-factor authentication mechanisms since its founding. The benefits of use of this stronger authentication method has been higher productivity and resource availability for users due to no known user account compromises caused by stolen NICS user credentials that led to disabling accounts or system resources. NICS has been developing and experimenting with expanding our use of multi-factor authentication to the grid. NICS has integrated multi-factor authentication with our certificate authority so that users can now run my proxy and receive a multi-factor authenticated certificate. NICS is also exploring the federation of multi-factor authentication systems, with the goal of "one user, one token". This is especially important, as new grid resources, such as Blue Waters, will only allow multi-factor authentication, and we want the users to only carry one token, not many tokens. XSEDE, the TeraGrid successor, will also be deploying multi-factor authentication in addition to the other existing authentication methodologies. XSEDE will also work closely with science gateways and workflows to develop and maintain secure frameworks for the highest level of security possible.
A waveform independent gate model for accurate timing analysis (2006)

In nanoscale regime, it is becoming increasingly difficult to model signal shapes using simple ramp-like waveforms due to various noise coupling effects. We present an accurate waveform independent gate (WiM) model without any assumption of signal waveforms. Our model can be applied to arbitrary gate inputs while maintaining excellent near-SPICE accuracy. The application of the proposed gate modeling technique is demonstrated under the context of the gate-level timing simulation.
Identifying and Locating Surface Defects in Wood: Part of an Automated Lumber Processing System (1983)

Continued increases in the cost of materials and labor make it imperative for furniture manufacturers to control costs by improved yield and increased productivity. This paper describes an Automated Lumber Processing System (ALPS) that employs computer tomography, optical scanning technology, the calculation of an optimum cutting strategy, and a computer-driven laser cutting device. While certain major hardware components of ALPS are already commercially available, a major missing element is the automatic inspection system needed to locate and identify surface defects on boards. This paper reports research aimed at developing such an inspection system. The basic strategy is to divide the digital image of a board into a number of disjoint rectangular regions and classify each independently. This simple procedure has the advantage of allowing an obvious parallel processing implementation. The study shows that measures of tonal and pattern related qualities are needed. The tonal measures are the mean, variance, skewness, and kurtosis of the gray levels. The pattern related measures are those based on cooccurrence matrices. In this initial feasibility study, these combined measures yielded an overall 88.3 percent correct classification on the eight defects most commonly found in lumber. To minimize the number of calculations needed to make the required classifications a sequential classifier is proposed.
Discrete multi-tone modulation for low-cost and robust 10-Gb/s transmission over polymer optical fibre (2007)

Utilizing a transmission bandwidth of 2 GHz, we demonstrate 10.6-Gb/s transmission (11.9-Gb/s including overhead) over 100 m of 120-pm core-diameter graded-index polymer optical fibre with discrete multi-tone modulation, achieving a spectral efficiency of 5.3 bit/s/Hz. (2 pages)