gebhart/patrepeval huggingface dataset:
End-to-end equalization experiments in amplified WDM lightwave systems (1993)

It is experimentally verified that signal-to-noise ratio equalization in amplified wavelength-multiplexed lightwave systems can be achieved by adjusting input optical signal powers according to a simple algorithm. The experiment involved four channels spaced by 2 nm transmitted through 550 km of fiber with the aid of eight erbium-doped optical amplifiers.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Heteroarenobenzodiazepines. 3. 4-Piperazinyl-10H-thieno[2,3-b][1,5]benzodiazepines as potential neuroleptics (1980)

A series of 4-substituted 10H-theino[2,3-b][1,5]benzodiazepines has been synthesized. These compounds have been assessed for their ability to block a conditioned avoidance response (CAR) and to produce catalepsy in rats and have been compared with several typical and atypical neuroleptics. The compounds which inhibit CAR at doses which produce no catalepsy are believed to cause less extrapyramidal side effects in the clinic. A number of compounds (9, 12, 17, 29, and 34) show potent neuroleptic activity, yet maintain a favorable separation of activity on these two parametrs. Three 5-piperazinyl-10H-thieno[2,3-b][1,4]benzodiazepine derivatives (46-48) analogous to compounds in the [1,5] series have been prepared for comparison and were found to be inactive.
Characterization of the tunable response of highly strained compliant optical metamaterials (2011)

Metamaterial designs are typically limited to a narrow operating bandwidth that is predetermined by the fabricated dimensions. Various approaches have previously been used to introduce post-fabrication tunability and thus enable active metamaterials. In this work, we exploit the mechanical deformability of a highly compliant polymeric substrate to achieve dynamic, tunable resonant frequency shifts greater than a resonant linewidth. We investigate the effect of metamaterial shape on the plastic deformation limit of resonators. We find that, for designs in which the local strain is evenly distributed, the response is elastic under larger global tensile strains. The plastic and elastic limits of resonator deformation are explored and the results indicate that, once deformed, the resonators operate within a new envelope of elastic response. We also demonstrate the use of coupled resonator systems to add an additional degree of freedom to the frequency tunability and show that compliant substrates can be used as a tool to test coupling strength. Finally, we illustrate how compliant metamaterials could be used as infrared sensors, and show enhancement of an infrared vibration absorption feature by a factor of 225.
Low Complexity Techniques for SCMA Detection (2015)

Sparse code multiple access (SCMA) is a codebook- based non-orthogonal multiplexing technique. In SCMA, the procedure of bit to QAM symbol mapping and spreading of CDMA are combined together and incoming bits are directly mapped to multi-dimensional codewords of SCMA codebook sets. Due to the sparse nature of codewords, SCMA enjoys the low complexity reception, taking advantage of a near optimal message passing algorithm (MPA). This makes SCMA a candidate for supporting massive connectivity in future 5G networks, where the number of users can potentially be higher than the codeword length (spreading factor). To this end, more efficient reception techniques are needed on top of what MPA delivers. In this paper, some complexity reduction techniques are presented to further reduce the SCMA decoding complexity. These techniques are considered from two perspectives: i) transmitter-side technique, by designing SCMA codebooks with a specific structure providing low complexity of detections, and ii) low complexity decoding techniques taking advantage of the SCMA codebook structure. The proposed techniques are evaluated in terms of both complexity and performance. It is shown that significant amount of complexity reduction is possible using the proposed techniques with negligible performance penalty, which paves the way of supporting various applications in future 5G systems using SCMA.
Reproducible Electrodeposition Technique for Immobilizing Glucose Oxidase (1994)

Two novel technologies have been developed to address problems associated with the fabrication of a miniature electroenzymatic glucose sensor for implantation in the subcutaneous tissue of humans with diabetes. An electrodeposition technique was developed to electrically attract glucose oxidase and albumin onto the surface of the working electrode of the glucose sensor. The resulting enzyme/albumin layer was chemically crosslinked with glutaraldehyde. This technique facilitated the simultaneous deposition of enzyme onto numerous miniature sensors. A polyethylene glycol (PEG)/polyurethane copolymer was developed for use as the outer membrane on the sensor. This membrane was designed and optimized to provide differential permeability of oxygen relative to glucose in order to avoid the oxygen deficit encountered in physiologic tissues. The membrane was also found to be highly biocompatible.
Development of Process Alternatives for Separation and Purification of Isoflavones (2006)

This article demonstrates the application of an integrative process development approach that combines conceptual design and bench-scale experiments to develop realistic process alternatives for the separation and purification of isoflavones from soybeans. The procedure begins with a generic process structure and the chemistry of the compounds involved. Basic data such as solid−liquid equilibrium phase behavior and chromatograms are then generated. The conceptual design calls for the recovery of the isoflavones as a mixture first using either chromatography or antisolvent crystallization. This step is followed by fractionation of this mixture into pure products, namely, daizein and genistein, using either chromatography or fractional crystallization.
The SCA12 Mutation as a Rare Cause of Spinocerebellar Ataxia (2001)

These results, coupled with findings in other populations, indicate that the SCA12 mutation is a rare cause of spinocerebellar degeneration. Diagnostic testing for SCA12 should be considered in patients with cerebellum disorders and an atypical clinical phenotype, especially when tremor is initially present.
FROM SEMANTICOBJECTS TO STRUCTURED NATURAL LANGUAGE (2007)

This paper presents a structured natural language (SNL) based on an object-relational algebra that allows users pose database queries whose scope is much wider than that of the relational algebra. We also discuss how queries expressed in natural language (NL) may be translated into SNL using meta-information.
Principles of an Electronic Neutron Dosemeter Using a PIPS Detector (1992)

Principles of an Electronic Neutron Dosemeter Using a PIPS Detector Get access B. Barelaud, B. Barelaud Search for other works by this author on: Oxford Academic PubMed Google Scholar D. Paul, D. Paul Search for other works by this author on: Oxford Academic PubMed Google Scholar B. Dubarry, B. Dubarry Search for other works by this author on: Oxford Academic PubMed Google Scholar L. Makovicka, L. Makovicka Search for other works by this author on: Oxford Academic PubMed Google Scholar J.L. Decossas, J.L. Decossas Search for other works by this author on: Oxford Academic PubMed Google Scholar J.C. Vareille J.C. Vareille Search for other works by this author on: Oxford Academic PubMed Google Scholar Radiation Protection Dosimetry, Volume 44, Issue 1-4, 1 November 1992, Pages 363–366, https://doi.org/10.1093/rpd/44.1-4.363 Published: 01 November 1992
Biochemical modification of streptavidin and avidin: in vitro and in vivo analysis. (1996)

Biochemical modification of SA and avidin resulted in altered pharmacokinetics compared to the native proteins. Modified SA or avidin, when cross-linked with a lesion-specific targeting agent, may be applicable for rapid two-step in vivo imaging techniques.
<title>Using rate staggering to store scalable video data in a disk-array-based video server</title> (1995)

This paper provides a data placement method based on rate staggering to store scalable video data in a disk-array-based video server. A scalable, or layered, video stream is one which is encoded in a manner that permits the extraction of lower resolution subsets from the full- resolution video bit stream. It is desirable to support layered video streams from a video server since these can be used to serve a variety of clients with different decoding capabilities. When a layered video stream is stored on a disk array, the video data corresponding to different rates of the video clip are not required to reside in the same disk. In view of this, we propose and explore the approach of rate staggering, i.e., staggering video data in the disk array based on data rates. It is shown that the advantages of the proposed rate staggering method include: (1) minimizing the intermediate buffer space required at the server, (2) achieving better load balancing due to finer scheduling granularity, and (3) alleviating the disk bandwidth fragmentation. These advantages enable a video server using the rate staggering method to provide feasible solutions to some video stream requests which cannot be met otherwise. The system throughput can thus be increased.
Electronic Transport and Quantum Hall Effect in Bipolar Graphene<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mi>p</mml:mi><mml:mtext mathvariant="normal">−</mml:mtext><mml:mi>n</mml:mi><mml:mtext mathvariant="normal">−</mml:mtext><mml:mi>p</mml:mi></mml:math>Junctions (2007)

We have developed a device fabrication process to pattern graphene into nanostructures of arbitrary shape and control their electronic properties using local electrostatic gates. Electronic transport measurements have been used to characterize locally gated bipolar graphene $p\mathrm{\text{\ensuremath{-}}}n\mathrm{\text{\ensuremath{-}}}p$ junctions. We observe a series of fractional quantum Hall conductance plateaus at high magnetic fields as the local charge density is varied in the $p$ and $n$ regions. These fractional plateaus, originating from chiral edge states equilibration at the $p\mathrm{\text{\ensuremath{-}}}n$ interfaces, exhibit sensitivity to interedge backscattering which is found to be strong for some of the plateaus and much weaker for other plateaus. We use this effect to explore the role of backscattering and estimate disorder strength in our graphene devices.
ChemInform Abstract: SULFAMYLUREA HYPOGLYCEMIC AGENTS. 6. HIGH‐POTENCY DERIVATIVES (1976)

Abstract Ca. 150 Sulfamylharnstoffe der allgemeinen Formeln (I)‐(IV) werden nach bekannten oder nach beschriebenen Verfahren hergestellt.
cDNA Cloning and Expression of Intracellular Platelet-activating Factor (PAF) Acetylhydrolase II (1996)

Platelet-activating factor (PAF) acetylhydrolase, which inactivates PAF by removing the acetyl group at the sn-2 position, is widely distributed in plasma and tissues. We previously demonstrated that tissue cytosol contains at least two types of PAF acetylhydrolase, isoforms Ib and II, and that isoform Ib is a heterotrimer comprising 45-, 30-, and 29-kDa subunits, whereas isoform II is a 40-kDa monomer. In this study, we isolated cDNA clones of bovine and human PAF acetylhydrolase isoform II. From the longest open reading frame of the cloned cDNAs, both bovine and human PAF acetylhydrolases II are predicted to contain 392 amino acid residues and to exhibit 88% identity with each other at the amino acid level. Both enzymes contain a Gly-X-Ser-X-Gly motif that is characteristic of lipases and serine esterases. Expression of isoform II cDNA in COS7 cells resulted in a marked increase in PAF acetylhydrolase activity. An immunoblot study using an established monoclonal antibody against the bovine enzyme revealed that the recombinant protein exists in the membranous fraction as well as the soluble fraction. Isoform II is expressed most abundantly in the liver and kidney in cattle, but low levels were also observed in other tissues. The amino acid sequence deduced from the cDNA of isoform II had no homology with any subunit of isoform Ib. Interestingly, however, the amino acid sequence of isoform II showed 41% identity with that of plasma PAF acetylhydrolase. Combined with previous data demonstrating that isoform II shows similar substrate specificity to plasma PAF acetylhydrolase, these results indicate that tissue type isoform II and the plasma enzyme may share a common physiologic function.
Tunable thermal links (2007)

We demonstrate that the thermal conductance K of individual multiwall carbon nanotubes can be controllably and reversibly adjusted by sliding the outer shells of the tube with respect to the inner core in a telescopinglike manner. K shows an exponential dependence on the telescoping distance. Tunable nanoscale thermal links have immediate implications for nano- to macroscale thermal management, biosystems, and phononic information processing.
Fused taper type fan-in/fan-out device for 12 core multi-core fiber (2014)

Fan-in/fan-out device for splicing to 12 core multi-core fiber is fabricated. Maximum loss of 4.7 dB at C-band and the worst crosstalk of -45 dB are confirmed in fan-in and fan-out with 20 m-long MCF.
Active property checking (2008)

Runtime property checking (as implemented in tools like Purify or Valgrind) checks whether a program execution satisfies a property. Active property checking extends runtime checking by checking whether the property is satisfied by all program executions that follow the same program path. This check is performed on a symbolic execution of the given program path using a constraint solver. If the check fails, the constraint solver generates an alternative program input triggering a new program execution that follows the same program path but exhibits a property violation. Combined with systematic dynamic test generation, which attempts to exercise all feasible paths in a program, active property checking defines a new form of dynamic software model checking (program verification). In this paper, we formalize and study active property checking. We show how static and dynamic type checking can be extended with active type checking. Then, we discuss how to implement active property checking efficiently. Finally, we discuss results of experiments with media playing applications on Windows, where active property checking was able to detect several new security-related bugs.
Automatic synthesis of multifork-like structures for multiple labeling of oligonucleotides: application to diagnosis of Lyme disease. (1995)

Multifork-like structures have been designed for multiple labelling of oligonucleotides. They rely on the synthesis of new non nucleosidic phosphoramidites which can be used in automatic DNA synthesis. The new compounds allowed tagging of any oligonucleotide and provided reactive primary amino groups for non isotopic labelling. Polybiotinylated oligonucleotides have been tested in hybridization assays using a corresponding complementary sequence covalently linked to polystyrene tubes. Detection limits ranged from 3.10(5) to 3.10(6) molecules, depending on the number of biotins. Multilabelled oligonucleotides have been included into a capture format to detect DNA of Borrelia burgdorferi, the causal agent of Lyme disease. In short, 5'-phosphate oligonucleotides were chemically condensed onto aminated microwells and served to capture PCR-amplified target DNA which, in turn, hybridized with polybiotinylated complementary oligonucleotides. Detection of the hybrids was achieved through streptavidin-conjugated peroxidase and a colorimetric substrate. The solid phase sandwich DNA hybridization assay proved highly specific, very sensitive, rapid and user friendly for the identification of spirochetal DNA in human biological specimens.
Optimization of Conductive Fins to Minimize UO2 Fuel Temperature and Radial Temperature Gradient (2023)

To further the development of low-enriched uranium fuels, precedence has been placed on delivering the same amount of power while lowering the fuel temperature and radial temperature gradient. To address this, modeling efforts have resulted in a novel design featuring conductive fins of varying thermal conductivities and geometries inserted into the fuel matrix. These conductive inserts were not allowed to exceed 6% of the original fuel volume. This constraint was imposed due to other designs displacing 10% of fuel volume. A parametric study was performed that consisted of 2.56 million BISON simulations involving varying fin characteristics (i.e., fin thermal conductivity, number, and geometry) to determine the optimal geometric configuration for a desired amount of fuel volume displaced. The results from this study show that the thickness and length of each fin affect the fuel temperature and temperature gradient more than varying the number and thermal conductivity of the fins. The parametric study resulted in the development of an optimized combination to produce the lowest peak fuel temperature, lowest radial temperature gradient, and highest temperature reduction for the amount of original fuel volume displaced. The simulations presented in this work will eventually be compared with irradiation experiments of similar fuel designs at Idaho National Laboratory’s Advanced Test Reactor.
Strategies for viral inactivation (1995)

The risk of transmission of viruses and other pathogenic organisms by blood can be reduced but not eliminated through donor selection and screening methodologies. The safety of blood derivatives prepared from plasma pools from thousands of donors requires virus inactivation, without which transmission rates approach certainty and with which safety can exceed that of single-donor products. Current inactivation methods have reduced and possibly eliminated the transmission of enveloped viruses, eg, hepatitis B and C viruses and HIV; newer methods, when coupled with existing methods, have the likelihood of providing products whose safety matches that of any pharmaceutical product. Success with the virus inactivation of pooled blood products has fostered research into inactivation methods that are compatible with erythrocyte concentrates and platelet concentrates. The most advanced of these employ light-activatable compounds. If successful, virtually all blood products can be free from transmitting viruses and other pathogenic organisms.
Development of a Prototype Design Process Recorder Based on Hypergraphs (1994)

Abstract We describe a design process recording method and a prototype implementation. They are being developed from data on several design projects, including an in-depth study of a 6-month long design effort, itself part of a multi-year aerospace research and design project. The work is also influenced by the larger context of other design research projects at Stanford. The recording method focuses on information generated in early stages of design that is at the same time easiest to capture and most useful to designers and engineers downstream. It does this by being based primarily on a design process model intended to reflect a designer’s point of view, and by taking advantage of practices that designers currently find useful. The method builds on the concept of an electronic notebook that has been described previously (Lakin et al., 1989). The record consists of connected pieces of information about the various concepts, notes, and documents that are central to an evolving design. We call the framework for the record a hypergraph: ‘graph’ because of its node-arc structure, and ‘hyper’ because it spans several types of information that are created during design work. To effectively convey the record’s contents to a downstream user, we propose a design story-teller style: the system’s response to a query takes the form of a storyboard of notes about related design episodes.
73 APPLICATION OF THE HOLLOW FIBER VITRIFICATION METHOD TO THE CRYOPRESERVATION OF HIGHLY CRYOSENSITIVE EMBRYOS (2014)

We recently demonstrated that the hollow fibre vitrification (HFV) method (Matsunari et al. 2012) could effectively be applied to the cryopreservation of embryos from diverse species. In this study, we applied the HFV method to the cryopreservation of highly cryosensitive specimens, such as in vitro matured (IVM)/IVF-derived porcine zona-free morulae and blastomeres isolated from those morulae, as well as IVM/IVF-derived cattle embryos at early cleavage stages. Porcine parthenogenetic morulae (d-4) derived from IVM oocytes were treated with 0.25% pronase to remove zona pellucidae. The resulting blastomeres were isolated from the zona-free morulae by a decompaction treatment followed by gentle pipetting. Bovine IVM-IVF embryos at the 2 to 4 cell (d-1), 8 to 16 cell (d-3), and morula stages (d-5) were then subjected to vitrification. The HFV procedure was performed as described previously using 15% dimethyl sulfoxide, 15% ethylene glycol, and 0.5 M trehalose as cryoprotectants. Four to twenty embryos, or all of the blastomeres isolated from a single morula, were individually loaded into a cellulose acetate hollow fibre (25 mm long, 185 µm f, 15 µm membrane thickness) and vitrified. Survival of the vitrified embryos was assessed by in vitro development to blastocysts. Blastomeres recovered after vitrification were aggregated in micro-wells to examine their ability to form blastocysts. The HFV method was demonstrated to be effective for cryopreserving zona-free in vitro-produced porcine morulae and the blastomeres isolated from them (Table 1), as well as bovine IVM-IVF embryos at early cleavage stages. These data demonstrate that the HFV method is effective for highly cryosensitive specimens, such as IVM/IVF-derived porcine zona-free morulae and blastomeres isolated from those morulae, and IVM/IVF-derived cattle embryos at early cleavage stages. These achievements may expand the technological options in the production of cloned and genetically modified pigs that are useful for biomedical research. Table 1. Survival of zona-free porcine morulae and isolated blastomeres after vitrification (top) and blastocyst formation rates in bovine early-stage in vitro matured-IVF embryos after vitrification (bottom) This study was supported by JST, ERATO, the Nakauchi Stem Cell and Organ Regeneration Project, and MUIIBR.
19‐4: <i>Invited Paper</i> : Emissive Displays with Transfer‐Printed Microscale Inorganic LEDs (2017)

Major advances in flat panel displays can come from the pixel‐level integration of high performance microscale components fabricated on semiconductor wafers and transferred by advanced assembly methods onto large‐area substrates. Displays that use direct light emission from tiny inorganic light emitting diodes (µILEDs) have the potential to be very bright and power efficient. Transfer‐printing with elastomer stamps is a candidate assembly technology for making µILED displays, serving as the metaphorical bridge between the LED wafer and the display panel. This paper presents simple demonstrations of displays made from red, green, and blue µILEDs fabricated on gallium arsenide, silicon, and sapphire wafers, transferred to glass and plastic display substrates by transfer‐printing. The demonstrator displays exhibit interesting characteristics, including transparency, flexibility, repair‐ability, wide color gamut, and pulse‐width modulated active matrix driving schemes facilitated by transfer‐printed micro‐scale driver circuits.
Methodology to characterize the performance of IEEE 802.11 nodes to be deployed in multi-hop environments (2007)

This paper proposes an experimental methodology to characterize the performance of an IEEE 802.11 WLAN node that is going to be used in a wireless multi-hop network. The methodology parameterizes the (in)accuracy of the node to conduct carrier sensing measurements and its capacity to handle incoming and outgoing traffic concurrently. These two parameters characterize sources of unexpected information losses, instability, and unfairness. In this way, they help to design and analyze multi-hop deployments. Finally, the methodology is used in an experimental setup to characterize an actual wireless node.