gebhart/patrepeval huggingface dataset:
A frequency-domain high-speed bus signal integrity compliance model: Design methodology and implementation (2015)

This paper investigates channel/link frequency domain compliance in order to predict compatibility with a bus's chip I/O circuitry at its ends. Any channel can be associated with certain frequency domain parameter values which are easily calculated from the channel S-parameter matrix. A set of frequency domain parameters that can sufficiently describe a channel are defined in this paper. Using a genetic algorithm, the frequency domain parameter bounds in a multidimensional space describing PCIe-Gen3 (bus speed = 8 Gb/s) compliant channels are found. Details of the methodology used in order to arrive at the multidimensional frequency domain compliance model, model results and model simulation validation testing are presented.
Cyclization by a Specific Lactam Increases the Ability of Human Parathyroid Hormone (hPTH)-(1–31)NH2 to Stimulate Bone Growth in Ovariectomized Rats (1997)

Human parathyroid hormone (hPTH)-(1-31)NH2 (Ostabolin), which only stimulates adenylyl cyclase (AC) instead of AC and phospholipase-C as do hPTH(1-84) and hPTH(1-34), strongly stimulates femoral cortical and trabecular bone growth in ovariectomized (OVX) rats. Two side-chain lactams have been introduced in the hydrophilic face of the receptor-binding region of the fragment's Ser17-Val31 amphiphilic alpha-helix in an attempt to develop improved analogs for the treatment of osteoporosis. Replacing the polar Lys27 with an apolar Leu on the hydrophobic face of this alpha-helix and stabilizing the helix with a lactam between Glu22 and Lys26 produced a fragment, [Leu27]-cyclo(Glu22-Lys26)-hPTH(1-31)NH2, which had six times the AC-stimulating ability of hPTH(1-31)NH2 in ROS 17/2 rat osteosarcoma cells, but the other helix-stabilizing lactam derivative [Leu27]-cyclo(Lys26-Arg30)-hPTH(1-31)NH2 did not have a greater AC-stimulating ability than hPTH(1-31)NH2, to stimulate AC in ROS 17/2 rat osteosarcoma cells. As expected from AC stimulation being responsible for PTH's anabolic action, [Leu27]-cyclo(Glu22-Lys26)-hPTH(1-31)NH2 was, depending on the experimental design, a 1.4 to 2 times better stimulator of trabecular bone growth in the OVX rat model than either hPTH(1-31)NH2 or [Leu27]-cyclo(Lys26-Arg30)-hPTH(1-31)NH2. Thus, there is now a more potently anabolic derivative of hPTH(1-31)NH2, [Leu27]-cyclo(Glu22-Lys26)-hPTH(1-31)NH2, which might ultimately prove to be one of the more effective therapeutics for osteoporosis.
Frequency Domain Multi-channel Acoustic Modeling for Distant Speech Recognition (2019)

Conventional far-field automatic speech recognition (ASR) systems typically employ microphone array techniques for speech enhancement in order to improve robustness against noise or reverberation. However, such speech enhancement techniques do not always yield ASR accuracy improvement because the optimization criterion for speech enhancement is not directly relevant to the ASR objective. In this work, we develop new acoustic modeling techniques that optimize spatial filtering and long short-term memory (LSTM) layers from multi-channel (MC) input based on an ASR criterion directly. In contrast to conventional methods, we incorporate array processing knowledge into the acoustic model. Moreover, we initialize the network with beamformers’ coefficients. We investigate effects of such MC neural networks through ASR experiments on the real-world far-field data where users are interacting with an ASR system in uncontrolled acoustic environments. We show that our MC acoustic model can reduce a word error rate (WER) by 16.5% compared to a single channel ASR system with the traditional log-mel filter bank energy (LFBE) feature on average. Our result also shows that our network with the spatial filtering layer on two-channel input achieves a relative WER reduction of 9.5% compared to conventional beamforming with seven microphones.
Product counting using images with application to robot-based retail stock assessment (2015)

In this paper, we propose a novel method for obtaining product count directly from images recorded using a monocular camera mounted on a mobile robot. This has application in robot-based retail stock assessment problem where a mobile robot is used for monitoring the stock levels on the shelves of a retail store. The products are recognized by carrying out a nearest-neighbor search in the template feature space using a k-d tree. Unlike current approaches which only provide approximate stock level, we propose a method which can compute the exact number of discrete products visible in a given image. The product count is obtained by fitting bounding box around each product and removing them sequentially from the image. A second stage of grid-based search is carried out in the neighborhood of each detected product to detect new products which were missed out in the previous step. This detection is based on a confidence measure that includes various information such as histogram matching and spatial location. The efficacy of the proposed approach is demonstrated through experiments on different datasets obtained using robot camera as well as mobile phone camera. These results show that the robot-based retail stock assessment may become a viable alternative to the currently prevailing manual mode of carrying out these surveys.
Standardized fluoroscopy‐based technique to measure intraoperative cup anteversion (2017)

Direct anterior approach (DAA) with the patient lying supine has facilitated the use of intraoperative fluoroscopy and allows for standardized positioning of the patient. The current study presents a new technique to measure acetabular component anteversion using intraoperative fluoroscopy. The current paper describes a mathematical formula to calculate true acetabular component anteversion based on the acetabular component abduction angle and the c-arm tilt angle (CaT). The CaT is determined by tilting the c-arm until an external pelvic oblique radiograph with the equatorial plane of the acetabular component perpendicular to the fluoroscopy receptor is obtained. CaT is determined by direct reading on the C-arm device. The technique was validated using a radiopaque synbone model comparing the described technique to computed tomography anteversion measurement. The experiment was repeated 25 times. The difference in anteversion between the two measuring techniques was on average 0.2° (range -3.0-3.1). The linear regression coefficients evaluating the agreement between the experimental and control methods were 0.99 (95%CI 0.88-1.10, p < 0.001) and 0.33 (95%CI -1.53-2.20, p = 0.713) for the slope and intercept, respectively. The current study confirms that the described three-step c-arm acetabular cup measuring technique can reproducibly and reliably assess acetabular component anteversion in the supine position, as compared to CT-imaging. © 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 35:2307-2312, 2017.
Protective Effects of Functional Chicken Liver Hydrolysates against Liver Fibrogenesis: Antioxidation, Anti-inflammation, and Antifibrosis (2017)

Via an assay using an Amino Acid Analyzer, pepsin-digested chicken liver hydrolysates (CLHs) contain taurine (365.57 ± 39.04 mg/100 g), carnosine (14.03 ± 1.98 mg/100 g), and anserine (151.58 ± 27.82 mg/100 g). This study aimed to evaluate whether CLHs could alleviate thioacetamide (TAA)-induced fibrosis. A dose of 100 mg TAA/kg BW significantly increased serum liver damage indices and liver cytokine contents. Cell infiltration and monocytes/macrophages in livers of TAA-treated rats were illustrated by the H&E staining and immunohistochemical analysis of cluster of differentiation 68 (CD68, ED1), respectively. A significantly increased hepatic collagen accumulation was also observed and quantified under TAA treatment. A significant up-regulation of transforming growth factor-beta (TGF-β) and SMAD family member 4 (SMAD4) caused by TAA treatment further enhanced alpha smooth muscle actin (αSMA) gene and protein expressions. The liver antioxidant effects under TAA treatment were significantly amended by 200 and 600 mg CLHs/kg BW. Hence, the ameliorative effects of CLHs on liver fibrogenesis could be attributed by antioxidation and anti-inflmmation.
Catalytic oxidation of SO sub 2 to SO sub 3 in the presence of fly ash (1991)

This patent describes a combustion gas conditioning method whereby particulates are removed from the main stream of combustion gases containing sulfur dioxide in a flue by electrostatic precipitation means. It comprises: the steps of withdrawing from a location upstream of the electrostatic precipitation means a minor amount of the total volume of the combustion gases entering the flue, including the particulates associated with the minor amount of combustion gases; contacting the minor amount of combustion gases and particulates associated therewith with catalytic means to convert SO{sub 2} contained therein to SO{sub 3}; and mixing the minor amount of combustion gases and SO{sub 3} into the main stream of combustion gases and subjecting the mixture formed thereby to electrostatic precipitation; wherein the catalytic means is exposed to the combustion gases within an open gas flow passage whereby particulates freely flow therethrough without substantially interfering with the catalytic conversion of SO{sub 2} to SO{sub 3} by the catalytic means.
Priority-Based Duplicate Burst Transmission Mechanism in Optical Burst Switching Networks (2008)

This paper proposes a priority-based duplicate burst transmission mechanism in an optical burst switching network to enhance lhe probability of successful reception of bursts. The performance of the proposed mechanism is evaluated by NS2 simulations. Our results show that the burst loss rate is improved especially under light traffic loads.
Optimizing array reference checking in Java programs (1998)

The Java™ language specification requires that all array references be checked for validity. If a reference is invalid, an exception must be thrown. Furthermore, the environment at the time of the exception must be preserved and made available to whatever code handles the exception. Performing the checks at run time incurs a large penalty in execution time. In this paper we describe a collection of transformations that can dramatically reduce this overhead in the common case (when the access is valid) while preserving the program state at the time of an exception. The transformations allow trade-offs to be made in the efficiency and size of the resulting code, and are fully compliant with the Java language semantics. Preliminary evaluation of the effectiveness of these transformations shows that performance improvements of 10 times and more can be achieved for array-intensive Java programs.
Bio-inspired method and system for actionable intelligence (2009)

This paper describes a bio-inspired VISion based actionable INTelligence system (VISINT) that provides automated capabilities to (1) understand objects, patterns, events and behaviors in vision data; (2) translate this understanding into timely recognition of novel and anomalous entities; and (3) discover underlying hierarchies and relationships between disparate labels entered by multiple users to provide a consistent data representation. VISINT is both a system and a novel collection of novel bio-inspired algorithms/modules. These modules can be used independently for various aspects of the actionable intelligence problem or sequenced together for an end-to-end actionable intelligence system. The algorithms can be useful in many other applications such as scene understanding, behavioral analysis, automatic surveillance systems, etc. The bio-inspired algorithms are a novel combination of hierarchical spatial and temporal networks based on the Adaptive Resonance Theory (ART). The novel aspects of this work are that it is an end-to-end system for actionable intelligence that combines existing and novel implementations of various modules in innovative ways to develop a system concept for actionable intelligence. Although there are other algorithms/implementations of several of the modules in VISINT, they suffer from various limitations and often system integration is not considered. The overall VISINT system can be viewed an incremental learning system where no offline training is required and data from multiple sources and times can be seamlessly integrated. The user is in the loop, but due to the semi-supervised nature of the underlying algorithms, only significant variations of entities, not all false alarms, are shown to the user. It does not forget the past even with new learning. While VISINT is designed as a vision-based system, it could also work with other kinds of sensor data that can recognize and locate individual objects in the scene. Beyond that stage of object recognition and localization, all aspects of VISINT are applicable to other kinds of sensor data.
P‐6: Static Reliability of Bridged‐Grain Poly‐Si TFTs (2014)

Abstract The characteristics of bridged‐grain (BG) poly‐Si thin film transistors (TFTs) with different BG periods and the static reliability of BG poly‐Si TFTs was examined and discussed. The characterizations show that the length of the sub‐channels mainly affects the on‐state current and the sub‐threshold characteristics. BG TFTs exhibit better hot carrier reliability, better self‐heating reliability, better negative bias temperature instability and good immunity against water.
Photocontrol of spin-glass state in Mg1.5FeTi0.5O4 spinel ferrite films (2000)

A spin-glass state up to 210 K has been found in (Mg, Fe){Mg,Fe,Ti}2O4 spinel ferrite thin films formed on α-Al2O3(0001) substrates. The films exhibit long-time relaxation of the magnetization in zero-field-cooled operation below 210 K; also, the ac susceptibility measurements show the presence of frequency-dependent cusp temperature. Both of the above observations are characteristic features of a spin glass. The change of magnetic state in the films from a spin glass to ferrimagnet has been achieved over a wide temperature range below 160 K by means of light irradiation.
Rapid polyclonal desensitization with monoclonal antibodies (125.15) (2012)

Abstract Rapid desensitization, a procedure in which individuals allergic to an antigen are treated at short intervals with increasing doses of that antigen until they tolerate a large dose, is an effective, albeit risky way to induce temporary tolerance. We have adapted this procedure to suppress IgE- or IgG-mediated immediate hypersensitivity in mice by injecting them with activating mAbs to IgE, FcϵRIα, or FcγRII/RIII, starting with doses too small to induce detectable reactions and doubling doses every 90 minutes. Rapid desensitization with anti-IgE mAb suppressed IgE-mediated immediate hypersensitivity; however, some mice developed mild anaphylaxis during desensitization. Rapid desensitization with an anti-FcϵRIα mAb that only binds FcϵRI that is not occupied by IgE suppressed both active and passive IgE-mediated anaphylaxis and induced no detectable reactions, but took several days to become fully effective by eliminating nearly all mast cell FcϵRI. Rapid desensitization with this mAb also rapidly, but temporarily, desensitized mast cells by decreasing their responsiveness to FcϵRI crosslinking. Rapid desensitization with anti-FcγRII/RIII mAb induced no detectable adverse reactions and rapidly suppressed IgG-mediated anaphylaxis. Similar approaches with mAbs to human IgE or IgG receptors may be useful as prophylaxis for human immediate hypersensitivity disorders, including anaphylaxis, food allergy, atopic dermatitis and asthma.
Experimental Progress in Linear Optics Quantum Computing (2003)

Probabilistic quantum logic operations can be performed using linear optical elements and post-selection based on the results of measurements on ancilla photons. We review the results of a number of recent experiments in this area, including the demonstration of several quantum logic gates, the use of feed-forward control, a new source of single photons, and a quantum memory device for single photons. A high-fidelity approach in which the logic gates always produce an output will also be discussed.
Hard-of-hearing aid appliance (1983)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Yozo Marutake, Tatsuro Fukutome, Kunihiko Fukuhama; Hard‐of‐hearing aid appliance. J. Acoust. Soc. Am. 1 June 1983; 73 (6): 2247. https://doi.org/10.1121/1.389476 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAcoustical Society of AmericaThe Journal of the Acoustical Society of America Search Advanced Search |Citation Search
EphA3 As a Target For Monoclonal Antibody Therapy For Acute Leukemia (2013)

Abstract Eph receptor tyrosine kinases interact with cell-surface ephrin ligands to direct cell growth, migration and cell positioning. High expression of EphA3 in a number of cancers has been linked to progression through facilitation of invasiveness and metastatic spread. EphA3 protein, which was originally described in leukemia, has also reported to be expressed in sarcomas, lung cancer, melanoma and glioblastoma. Using a Humaneered® derivative of the IIIA4 anti-EphA3 monoclonal antibody, KB004 (KaloBios Pharmaceuticals Inc), a clinical trial has commenced which targets the EphA3 protein in leukemia. The EphA3-specific monoclonal antibody, IIIA4, binds and activates human and mouse EphA3 with similar affinities, binding is followed by internalization of receptor-antibody complexes. We have shown high expression of EphA3 in the LK63 pre-B ALL and no expression of EphA3 in the Reh, a similar pre-B ALL cell line. We have examined the effect of the IIIA4 antibody in LK63 and Reh NOD/SCID xenograft models. In the LK63 xenograft model, administration of the IIIA4 antibody led to inhibition of tumour growth and decrease spread from bone marrow to the spleen and other organs and increased the latency of the disease, however no reduction in engraftment was observed in Reh xenograft model, suggesting that the effect was directed against the leukemic cells rather than the stromal and vascular elements. To further analyse the function of EphA3 expression, LK63 EphA3 knock down and EphA3-transfected Reh cells were tested in the xengraft model. Similar to LK63, antibody-treated Reh EphA3 xenografts showed reduction in the bone marrow engraftment and increased the latency of the disease. In contrast, LK63 EphA3 knock down xenografts showed minimal difference between treated and control group but notably showed a significant reduction in the splenic engraftment compared to the normal LK63 model. These results are consistent with IIIA4-mediated effects on the growth of EphA3-positive leukemic cells in the bone marrow and a secondary effect on the subsequent spread of the leukemic cells to extra-medullary sites and provides evidence that EphA3 is a functional therapeutic target in acute leukemias. Disclosures: No relevant conflicts of interest to declare.
Nature and origin of asphaltenes in processed coals. Final report. [Especially of initial phases and products; 50 references] (1979)

The development of improved liquefaction technology requires a thorough understanding of the chemistry and mechanisms involved in converting coals to liquid fuels. The primary objectives of EPRI Project 410-1 were to develop such fundamental understanding of the thermal solvent refining of coal. This report constitutes the final report of a four year study. It consists of three volumes. The first volume contains a critical review of the chemistry and basic limitations of today's developing liquefaction processes, an overall summary of the significance of the results of the four-year project to present-day processes, and a detailed review of the last 1 1/2 years of the project. The second volume contains the bulk of the experimental work in the last 1 1/2 years of the project as well as a literature review of specific topics. Volume III contains the pertinent Appendices. Throughout this report, emphasis is placed on the initial phases of coal liquefaction with special attention to the chemical functionality, structure and properties of the initial products of coal. This chemistry is related to the basic constraints imposed on commercial processes such as achievable reaction times, temperatures, pressures, and production and chemical constitution of recycle solvents which are required for coal conversion. In the critical review of limitations of present-day technology, we attempt to integrate the understanding of the chemistry developed and suggest possible means to improve these processes.
Positive Selection of Novel Peroxisome Biogenesis-Defective Mutants of the Yeast Pichia pastoris (1999)

We have developed two novel schemes for the direct selection of peroxisome-biogenesis-defective (pex) mutants of the methylotrophic yeast Pichia pastoris. Both schemes take advantage of our observation that methanol-induced pex mutants contain little or no alcohol oxidase (AOX) activity. AOX is a peroxisomal matrix enzyme that catalyzes the first step in the methanol-utilization pathway. One scheme utilizes allyl alcohol, a compound that is not toxic to cells but is oxidized by AOX to acrolein, a compound that is toxic. Exposure of mutagenized populations of AOX-induced cells to allyl alcohol selectively kills AOX-containing cells. However, pex mutants without AOX are able to grow. The second scheme utilizes a P. pastoris strain that is defective in formaldehyde dehydrogenase (FLD), a methanol pathway enzyme required to metabolize formaldehyde, the product of AOX. AOX-induced cells of fld1 strains are sensitive to methanol because of the accumulation of formaldehyde. However, fld1 pex mutants, with little active AOX, do not efficiently oxidize methanol to formaldehyde and therefore are not sensitive to methanol. Using these selections, new pex mutant alleles in previously identified PEX genes have been isolated along with mutants in three previously unidentified PEX groups.
Production of Methanol: From Fossil Fuels and Bio‐Sources to Chemical Carbon Dioxide Recycling (2009)

This chapter contains sections titled: Methanol from Fossil Fuels Methanol through Methyl Formate Methanol from Methane without Producing Syn-Gas Methanol from Biomass, Including Cellulosic Sources Chemical Recycling of Carbon Dioxide to Methanol
Single-Pixel, Single-Layer Polymer Device as a Tricolor Sensor with Signals Mimicking Natural Photoreceptors (2011)

Color sensing procedures typically involve multiple active detectors or a photodetector coupled to a filter array. We demonstrate the possibility of using a single polymer layer based device structure for multicolor sensing. The device structure does not require any color filters or any subpixelation, and it distinguishes colors without any external bias. The color sensing relies on an appropriate thickness of the active polymer layer that results in a characteristic polarity and temporal profile of the photocurrent signal in response to various incident colors. The device characteristics reveal interesting similarities to the features observed in natural photosensitive systems including retinal cone cells.
1.5 μm pulse shaping by degenerate type II DFG with QPM gratings (2003)

Summary form only given. Manipulation of the temporal shape of ultrashort optical pulses is important for many applications. Here we demonstrate that degenerate type II difference frequency generation (DFG) with Fourier synthetic quasi-phase-matched (QPM) gratings can produce pulse-shaped signal at the same wavelength as the femtosecond input.