gebhart/patrepeval huggingface dataset:
Low-voltage sigma-delta modulator topologies for broadband applications (2004)

This paper proposes a class of sigma-delta modulator topologies for low-voltage, high-speed, and high-resolution applications with low oversampling ratios (OSRs). The main specifications of these architectures are the reduced analog circuit requirements, large out-of-band gain in the noise transfer function (NTF) without any stability concerns to achieve high signal to noise ratio (SNR) with a low OSR, and unity-gain signal transfer function (STF) to reduce the harmonic distortions resulted from the analog circuit imperfections.
Progression of Chronic Renal Disease in the Dog (1999)

Abstarct Progressive loss of nephron function may be caused by persistence of factors that initiated renal disease. However, newer studies suggest that nephron damage is self-perpetuating once renal mass is reduced to some critical level. Original theories on mechanisms of self-perpetuated nephron injury focused on intraglomerular hypertension and glomerular hypertrophy, but several other factors have now been incriminated, including tubulointerstitial responses, proteinuria, and oxidative stress. Studies of dogs with surgically reduced renal mass (remnant kidney model of chronic renal disease) have allowed investigation of the self-progression theory in this species. Use of this model eliminates pre-existing renal disease as a confounding factor. Data from these studies indicate that self-perpetuated renal injury is initiated when mild azotemia is induced (plasma creatinine concentration = 2 to 4 mg/dL). Thus, with naturally occurring renal disease(s), it is likely that self-perpetuated nephron damage is occurring before or at the time when most cases of chronic renal disease are diagnosed. In dogs with remnant kidneys, loss of renal function often occurs at a linear rate over time, but non-linear patterns are common as well. The reciprocal of plasma creatinine concentration, which has been used to monitor rate of progression, is only a fair marker of renal function when compared to GFR. Thus, clinical results from creatinine measurements on cases of naturally occurring disease should not be interpreted too stringently. In remnant kidney dogs, the magnitude of proteinuria (UPC ratio) was not predictive of the rate in decline of GFR, casting doubt on importance of proteinuria in causing progression of renal disease. However, progressive increases in UPC may be a marker of an accelerated rate of renal injury. Self-perpetuation of renal injury in dogs could be the sole mechanism by which naturally occurring renal diseases progress. When more information is available on the rate of progression of naturally occurring diseases, it may become apparent whether factors initially inciting renal damage have an additive effect on rate of progression.
Inexpensive but Highly Efficient Co–Mn Mixed‐Oxide Catalysts for Selective Oxidation of 5‐Hydroxymethylfurfural to 2,5‐Furandicarboxylic Acid (2018)

A highly active and inexpensive Co-Mn mixed-oxide catalyst was prepared and used for selective oxidation of 5-hydroxymethylfurfural (HMF) into 2, 5-furandicarboxylic acid (FDCA). Co-Mn mixed-oxide catalysts with different Co/Mn molar ratios were prepared through a simple solid-state grinding method-a low-cost and green catalyst preparation method. The activity of these catalysts was evaluated for selective aerobic oxidation of HMF into FDCA in water. Excellent HMF conversion (99 %) and FDCA yield (95 % ) were obtained under the best reaction conditions (i.e., 120 °C, 5 h, Co-Mn mixed-oxide catalyst with a Co/Mn molar ratio of 0.25 calcined at 300 °C (Co-Mn-0.25) and 1 MPa O<sub>2</sub> ). The catalyst could be reused five times without a significant decrease in activity. The results demonstrated that the catalytic activity and selectivity of the Co-Mn mixed-oxide catalysts prepared through solid-state grinding were superior to the same Co-Mn catalyst prepared through a conventional coprecipitation method. The high catalytic activity of the Co-Mn-0.25 catalyst was attributed to its high lattice oxygen mobility and the presence of different valence states of manganese. The high activity and low cost of the Co-Mn mixed-oxide catalysts prepared by solid-state grinding make it promising for industrial application for the manufacturing of polyethylene furanoate, a bioreplacement for polyethylene terephthalate, from sustainable bioresources.
Application-aware snoop filtering for low-power cache coherence in embedded multiprocessors (2008)

Maintaining local caches coherently in shared-memory multiprocessors results in significant power consumption. The customization methodology we propose exploits the fact that in embedded systems, important knowledge is available to the system designers regarding memory sharing between tasks. We demonstrate how the snoop-induced cache probings can be significantly reduced by identifying and exploiting in a deterministic way the shared memory regions between the processors. Snoop activity is enabled only for the accesses referring to known shared regions. The hardware support is not only cost efficient, but also software programmable, which allows for reprogrammability and customization across different tasks and applications.
Real Estate Tax is the Call of the Times (2009)

The article considers the real estate tax. The bills submitted to the Verkhovna Rada for consideration and adoption have been analysed. The today's condition of real estate market (the segment of housing real estate), good timing of introduction of real estate tax which can considerably influence the development of real estate market of Ukraine have been analyzed.
Energy-aware portable video communication system design for wildlife activity monitoring (2008)

In this paper, we introduce our recent research and development effort on energy-efficient portable video communication system design for wildlife activity monitoring. The capability of seeing what an animal sees in the field is very important for wildlife activity monitoring and research. We design an integrated video and sensor system, called DeerCam and mount it on animals so as to collect important video and sensor data about their activities in the field. From the video and sensor data collected by DeerCam, wildlife researchers will be able to extract a wealth of scientific data for studying the behavior patterns of wildlife species and understanding the dynamic of wildlife systems. We present the system architecture of DeerCam, explain our system design goals, and discuss major design issues. One of the central challenges in DeerCam system design is energy minimization. We present a new approach for energy minimization of portable video devices: power-rate-distortion (P-R-D) analysis and optimization. We discuss various approaches to minimizing the energy consumption of DeerCam, which can be also applied to other portable video devices. Results demonstrate that, by incorporating the third dimension of power consumption into conventional rate-distortion (R-D) analysis, P-R-D analysis gives us one extra dimension of flexibility in resource allocation and energy minimization and allows us to significantly reduce energy consumption.
A Modular Lentiviral and Retroviral Construction System to Rapidly Generate Vectors for Gene Expression and Gene Knockdown In Vitro and In Vivo (2013)

The ability to express exogenous cDNAs while suppressing endogenous genes via RNAi represents an extremely powerful research tool with the most efficient non-transient approach being accomplished through stable viral vector integration. Unfortunately, since traditional restriction enzyme based methods for constructing such vectors are sequence dependent, their construction is often difficult and not amenable to mass production. Here we describe a non-sequence dependent Gateway recombination cloning system for the rapid production of novel lentiviral (pLEG) and retroviral (pREG) vectors. Using this system to recombine 3 or 4 modular plasmid components it is possible to generate viral vectors expressing cDNAs with or without inhibitory RNAs (shRNAmirs). In addition, we demonstrate a method to rapidly produce and triage novel shRNAmirs for use with this system. Once strong candidate shRNAmirs have been identified they may be linked together in tandem to knockdown expression of multiple targets simultaneously or to improve the knockdown of a single target. Here we demonstrate that these recombinant vectors are able to express cDNA and effectively knockdown protein expression using both cell culture and animal model systems.
Tribological Dependence of the High-Performance Ferrous-Based Coating on Different Coating Counterparts in Engine Oil (2015)

A ferrous-based coating with significant chromium was fabricated on aluminum alloy substrate using a plasma spray technique. The tribological performance of the as-fabricated ferrous-based coating sliding against different coatings including Cr, CrN, TiN, and diamond-like carbon (DLC) in an engine oil environment were comparatively studied. Results showed that the high hardness of the sprayed ferrous-based coating was achieved due to the dispersion strengthening effect of Cr7C3 phase embedded in the austenite matrix. The ferrous-based coating exhibited low friction coefficients when coupled with these four coating counterparts, which could be attributed to the boundary lubricating effect of engine oil. However, both friction and wear of the ferrous-based coating were different when sliding against these different coating counterparts, which might be closely related to the surface roughness, self-lubricating effect, and mechanical properties of the coupled coatings. Ferrous-based coating sliding against CrN and DLC coatings exhibited good tribological performance in engine oil. The best coating counterpart for the ferrous-based coating in an engine was DLC coating.
Wadsley–Roth Crystallographic Shear Structure Niobium‐Based Oxides: Promising Anode Materials for High‐Safety Lithium‐Ion Batteries (2021)

Wadsley-Roth crystallographic shear structure niobium-based oxides are of great interest in fast Li<sup>+</sup> storage due to their unique 3D open tunnel structures that offer facile Li<sup>+</sup> diffusion paths. Their moderate lithiation potential and reversible redox couples hold the great promise in the development of next-generation lithium-ion batteries (LIBs) that are characterized by high power density, long lifespan, and high safety. Despite these outstanding merits, there is still extensive advancement space for further enhancing their electrochemical kinetics. And the industrial feasibility of Wadsley-Roth crystallographic shear structure niobium-based oxides as anode materials for LIBs requires more systematic research. In this review, recent progress in this field is summarized with the aim of realizing the practical applications of Wadsley-Roth phase anode materials in commercial LIBs. The review focuses on research toward the crystalline structure analyses, electrochemical reaction mechanisms, modification strategies, and full cell performance. In addition to highlighting the current research advances, the outlook and perspective on Wadsley-Roth anode materials is also concisely provided.
Breast Cancer Diagnosis in Digital Breast Tomosynthesis: Effects of Training Sample Size on Multi-Stage Transfer Learning Using Deep Neural Nets (2018)

In this paper, we developed a deep convolutional neural network (CNN) for the classification of malignant and benign masses in digital breast tomosynthesis (DBT) using a multi-stage transfer learning approach that utilized data from similar auxiliary domains for intermediate-stage fine-tuning. Breast imaging data from DBT, digitized screen-film mammography, and digital mammography totaling 4039 unique regions of interest (1797 malignant and 2242 benign) were collected. Using cross validation, we selected the best transfer network from six transfer networks by varying the level up to which the convolutional layers were frozen. In a single-stage transfer learning approach, knowledge from CNN trained on the ImageNet data was fine-tuned directly with the DBT data. In a multi-stage transfer learning approach, knowledge learned from ImageNet was first fine-tuned with the mammography data and then fine-tuned with the DBT data. Two transfer networks were compared for the second-stage transfer learning by freezing most of the CNN structures versus freezing only the first convolutional layer. We studied the dependence of the classification performance on training sample size for various transfer learning and fine-tuning schemes by varying the training data from 1% to 100% of the available sets. The area under the receiver operating characteristic curve (AUC) was used as a performance measure. The view-based AUC on the test set for single-stage transfer learning was 0.85 ± 0.05 and improved significantly (p <; 0.05$ ) to 0.91 ± 0.03 for multi-stage learning. This paper demonstrated that, when the training sample size from the target domain is limited, an additional stage of transfer learning using data from a similar auxiliary domain is advantageous.
CGI Programming with Perl (2000)

Preface 1. Getting Started History Introduction to CGI Alternative Technologies Web Server Configuration 2. The Hypertext Transport Protocol URLs HTTP Browser Requests Server Responses Proxies Content Negotiation Summary 3. The Common Gateway Interface The CGI Environment Environment Variables CGI Output Examples 4. Forms and CGI Sending Data to the Server Form Tags Decoding Form Input 5. CGI.pm Overview Handling Input with CGI.pm Generating Output with CGI.pm Alternatives for Generating Output Handling Errors 6. HTML Templates Reasons for Using Templates Server Side Includes HTML::Template Embperl Mason 7. JavaScript Background Forms Data Exchange Bookmarklets 8. Security The Importance of Web Security Handling User Input Encryption Perl's Taint Mode Data Storage Summary 9. Sending Email Security Email Addresses Structure of Internet Email sendmail mailx and mail Perl Mailers procmail 10. Data Persistence Text Files DBM Files Introduction to SQL DBI 11. Maintaining State Query Strings and Extra Path Information Hidden Fields Client-Side Cookies 12. Searching the Web Server Searching One by One Searching One by One, Take Two Inverted Index Search 13. Creating Graphics on the Fly File Formats Outputting Image Data Generating PNGs with GD Additional GD Modules PerlMagick 14. Middleware and XML Communicating with Other Servers An Introduction to XML Document Type Definition Writing an XML Parser CGI Gateway to XML Middleware 15. Debugging CGI Applications Common Errors Perl Coding Techniques Debugging Tools 16. Guidelines for Better CGI Applications Architectural Guidelines Coding Guidelines 17. Efficiency and Optimization Basic Perl Tips, Top Ten FastCGI mod_perl A. Works Cited and Further Reading B. Perl Modules Index
Femur Fractures Associated with Canine Total Hip Replacement (2004)

Femur fractures that occur after THR should be repaired using plate and screw fixation augmented with cerclage wire when needed. Forces on fissures should be neutralized to prevent propagation and fracture. Owners of high-risk patients (old dogs with osteopathies or previous hip surgery) should be counseled before THR. The prognosis is excellent when fractures are treated correctly.
Vestibular migraine: the most frequent entity of episodic vertigo (2016)

Vestibular migraine (VM) is the most common cause of episodic vertigo in adults as well as in children. The diagnostic criteria of the consensus document of the International Bárány Society for Neuro-Otology and the International Headache Society (2012) combine the typical signs and symptoms of migraine with the vestibular symptoms lasting 5 min to 72 h and exclusion criteria. Although VM accounts for 7% of patients seen in dizziness clinics and 9% of patients seen in headache clinics it is still underdiagnosed. This review provides an actual overview on the pathophysiology, the clinical characteristics to establish the diagnosis, the differential diagnosis, and the treatment of VM.
RELATIONSHIP BETWEEN RAINFALL AND DEBRIS FLOW OCCURRENCE IN THE CROCKER RANGE OF SABAH, MALAYSIA (2018)

Debris flow occurences are quite common in mountainous areas such as those in the Crocker Range of Sabah, Malaysia especially during prolonged heavy rainfall. Despite the recurrence of debris flows in the area, not much information is known about the effect of rainfall on their occurrences. Based on the rainfall intensity-duration of two selected case studies at Jalan Penampang-Tambunan KM38.80 and Jalan Tamparuli-Ranau KM83.90, the debris flow threshold for the Crocker Range cases are approximate to that proposed by This implies that low-intensity rainfall is sufficient to trigger debris flows due to high availability of loose material and weak geological condition.
Enhancement by Microencapsulation of Rotavirus-Specific Intestinal Immune Responses in Mice Assessed by Enzyme-Linked Immunospot Assay and Intestinal Fragment Culture (1995)

The capacity of microencapsulation to enhance the humoral immune response to rotavirus in the gut-associated lymphoid tissue (GALT) of mice was determined by using a system of microencapsulation based on the ionic linkage of aqueous anionic polymers and an aqueous amine. Inoculation of mice with microencapsulated rotavirus enhanced the frequencies of virus-specific IgA-secreting cells in the lamina propria as well as the quantities of virus-specific IgA produced in GALT. In addition, an enhanced virus-specific immune response was associated with enhanced production of presumably polyclonal, non-rotavirus-specific antibodies in GALT. The mechanism by which microencapsulation enhances the humoral immune response remains to be determined.
A wideband coplanar waveguide-fed circularly polarised antenna (2008)

A wideband coplanar waveguide (CPW)-fed circularly polarised antenna is presented. It contains two loops arranged in an unusual way. One unique feature is that the positive signal line of the CPW is split into one vertical and one horizontal arm after a simple match. Another large surrounding open ring is used to suppress the surface wave. The antenna has more than 20% 10 dB return loss and 3 dB axial ratio bandwidth.
The Combination of Carboxylesterase-Expressing Oncolytic Vaccinia Virus and Irinotecan (2013)

This project combines oncolytic Vaccinia virus (VV) with irinotecan (CPT-11) for the treatment of cancer. VV can infect, replicate in and destroy cancer cells, yet leave healthy cells relatively unaffected. CPT-11 is a chemotherapeutic of which ~5% is converted to the more active chemotherapeutic SN-38 by endogenous carboxylesterase (CE) enzymes. SN-38 is a topoisomerase I inhibitor that induces DNA double strand breaks, leading to growth arrest and apoptosis. Consequently, VV has been engineered to express a more effective isoform of the CE enzyme. The virus’ tumour tropism should restrict enhanced conversion of CPT-11 to the tumour. Neither CPT-11 nor SN-38 interfered with VV replication or spread. Engineered recombinants expressed CE enzyme which, when combined with CPT-11, produced DNA double strand breaks and cancer cell death. In vitro, the combination of CE-virus and CPT-11 killed more K-562 cancer cells than its non-CE counterpart and CPT-11.
Scalable and Media Aware Adaptive Video Streaming over Wireless Networks (2008)

This paper proposes an advanced video streaming system based on scalable video coding in order to optimize resource utilization in wireless networks with retransmission mechanisms at radio protocol level. The key component of this system is a packet scheduling algorithm which operates on the different substreams of a main scalable video stream and which is implemented in a so-called media aware network element. The concerned type of transport channel is a dedicated channel subject to parameters (bitrate, loss rate) variations on the long run. Moreover, we propose a combined scalability approach in which common temporal and SNR scalability features can be used jointly with a partitioning of the image into regions of interest. Simulation results show that our approach provides substantial quality gain compared to classical packet transmission methods and they demonstrate how ROI coding combined with SNR scalability allows to improve again the visual quality.
Field-Evolved Insect Resistance to <I>Bt</I> Crops: Definition, Theory, and Data (2009)

Transgenic crops producing Bacillus thuringiensis (Bt) toxins for insect pest control have been successful, but their efficacy is reduced when pests evolve resistance. Here we review the definition of field-evolved resistance, the relationship between resistance and field control problems, the theory underlying strategies for delaying resistance, and resistance monitoring methods. We also analyze resistance monitoring data from five continents reported in 41 studies that evaluate responses of field populations of 11 lepidopteran pests to four Bt toxins produced by Bt corn and cotton. After more than a decade since initial commercialization of Bt crops, most target pest populations remain susceptible, whereas field-evolved resistance has been documented in some populations of three noctuid moth species: Spodoptera frugiperda (J. E. Smith) to Cry1F in Bt corn in Puerto Rico, Busseola fusca (Fuller) to CrylAb in Bt corn in South Africa, and Helicoverpa zea (Boddie) to CrylAc and Cry2Ab in Bt cotton in the southeastern United States. Field outcomes are consistent with predictions from theory, suggesting that factors delaying resistance include recessive inheritance of resistance, abundant refuges of non-Bt host plants, and two-toxin Bt crops deployed separately from one-toxin Bt crops. The insights gained from systematic analyses of resistance monitoring data may help to enhance the durability of transgenic insecticidal crops. We recommend continued use of the longstanding definition of resistance cited here and encourage discussions about which regulatory actions, if any, should be triggered by specific data on the magnitude, distribution, and impact of field-evolved resistance.
Cyclotide Structure–Activity Relationships: Qualitative and Quantitative Approaches Linking Cytotoxic and Anthelmintic Activity to the Clustering of Physicochemical Forces (2014)

Cyclotides are a family of plant-derived proteins that are characterized by a cyclic backbone and a knotted disulfide topology. Their cyclic cystine knot (CCK) motif makes them exceptionally resistant to thermal, chemical, and enzymatic degradation. Cyclotides exert much of their biological activity via interactions with cell membranes. In this work, we qualitatively and quantitatively analyze the cytotoxic and anthelmintic membrane activities of cyclotides. The qualitative and quantitative models describe the potency of cyclotides using four simple physicochemical terms relevant to membrane contact. Specifically, surface areas of the cyclotides representing lipophilic and hydrogen bond donating properties were quantified and their distribution across the molecular surface was determined. The resulting quantitative structure-activity relation (QSAR) models suggest that the activity of the cyclotides is proportional to their lipophilic and positively charged surface areas, provided that the distribution of these surfaces is asymmetric. In addition, we qualitatively analyzed the physicochemical differences between the various cyclotide subfamilies and their effects on the cyclotides' orientation on the membrane and membrane activity.