gebhart/patrepeval huggingface dataset:
Extrinsic Fabry-Perot Optical Fiber Sensor (1992)

Phase-modulated fiber optic sensors have been shown to possess high sensitivities for the measurement of strain, temperature, vibration, pressure and other parameters.1 Fabry-Perot (FP) sensors that are based on multiple beam interference eliminate the need for a reference arm and do not require sophisticated stabilization techniques as in the case of Mach-Zehnder and Michelson interferometers.2 Several techniques to create intrinsic optical fiber Fabry-Perot interferometers have been described in the past.3-5 In a recent paper, we described an optical fiber extrinsic FP interferometer and used it as a sensor of microdisplacements and thermally- induced strain.6 The fiber interferometer was classified as extrinsic because the FP cavity was an air-gap between two fiber ends and the sensor output was immune to perturbations in the input/output fiber.
HEBS: Histogram Equalization for Backlight Scaling (2007)

ABSTRACT- In this paper, a method is proposed for finding a pixel transformation function that maximizes backlight dimming while maintaining a pre-specified image distortion level for a liquid crystal display. This is achieved by finding a pixel transformation function, which maps the original image histogram to a new histogram with lower dynamic range. Next the contrast of the transformed image is enhanced so as to compensate for brightness loss that would arise from backlight dimming. The proposed approach relies on an accurate definition of the image distortion which takes into account both the pixel value differences and a model of the human visual system and is amenable to highly efficient hardware realization. Experimental results show that the histogram equalization for backlight scaling method results in about 45 % power saving with an effective distortion rate of 5 % and 65 % power saving for a 20% distortion rate. This is significantly higher power savings compared to previously reported backlight dimming approaches. 1
Substituted 6-Phenyl-2-naphthols. Potent and Selective Nonsteroidal Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 1 (17β-HSD1): Design, Synthesis, Biological Evaluation, and Pharmacokinetics (2008)

17beta-Estradiol (E2) is implicated in the genesis and the development of estrogen-dependent diseases. Its concentration is mainly regulated by 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1), which catalyzes the reduction of the weak estrogen estrone (E1) to the highly potent E2. This enzyme is thus an important target for the treatment of hormone-dependent diseases. Thirty-seven novel substituted 6-phenyl-2-naphthols were synthesized and evaluated for 17beta-HSD1 inhibition, selectivity toward 17beta-HSD2 and the estrogen receptors (ERs) alpha and beta, and pharmacokinetic properties. SAR studies revealed that the compounds most likely bind according to binding mode B to the active site, i.e., the 6-phenyl moiety mimicking the steroidal A-ring. While substitution at the phenyl ring decreased activity, introduction of substituents at the naphthol moiety led to highly active compounds, especially in position 1. The 1-phenyl compound 32 showed a very high inhibitory activity for 17beta-HSD1 (IC50 = 20 nM) and good selectivity (17beta-HSD2 and ERs) and pharmacokinetic properties after peroral application.
Simplified Pretubulysin Derivatives and Their Biological Effects on Cancer Cells (2014)

Tubulin binding agents are a potent group of cancer chemotherapeutics. Most of these substances are naturally derived compounds. A novel substance class of destabilizing agents is the group of tubulysins. The tubulysins and their derivative pretubulysin have shown high efficacy in vitro and in vivo. Due to their complex chemical structures, one major bottleneck of the tubulysins is their accessibility. Biotechnological as well as chemical production is challenging, especially on larger scales. Thus, the synthesis of chemically simplified structures is needed with retained or improved biological activity. Herein is presented the biological evaluation of two pretubulysin derivatives [2-desmethylpretubulysin AU816 (1) and phenylpretubulysin JB337 (2)] in comparison to pretubulysin. Both 1 and 2 display a simplification in chemical synthesis. It was shown that both compounds exhibited potent biological activity against cancer cells. These simplified compounds inhibited tubulin polymerization in the nanomolar range. The cytotoxic effects of 1 and 2 were in a similar range, when compared with pretubulysin [IC50 (nM): pretubulysin: 0.6; 1: 10; 2: 100]. Furthermore, it was shown that cell cycle arrest is induced and migration is hampered in MDA-MB-231 breast cancer cells. In conclusion, 1 was shown to be about 10-fold more active than 2 and as potent as pretubulysin.
Nonlinear-Based MEMS Sensors and Active Switches for Gas Detection (2016)

The objective of this paper is to demonstrate the integration of a MOF thin film on electrostatically actuated microstructures to realize a switch triggered by gas and a sensing algorithm based on amplitude tracking. The devices are based on the nonlinear response of micromachined clamped-clamped beams. The microbeams are coated with a metal-organic framework (MOF), namely HKUST-1, to achieve high sensitivity. The softening and hardening nonlinear behaviors of the microbeams are exploited to demonstrate the ideas. For gas sensing, an amplitude-based tracking algorithm is developed to quantify the captured quantity of gas. Then, a MEMS switch triggered by gas using the nonlinear response of the microbeam is demonstrated. Noise analysis is conducted, which shows that the switch has high stability against thermal noise. The proposed switch is promising for delivering binary sensing information, and also can be used directly to activate useful functionalities, such as alarming.
New approaches in obtaining nano- and microstructured metal oxide materials with improved properties and functionality (2011)

Sol-gel has emerged as an alternative to conventional methods of preparing oxide materials. Sol-gel technology has many advantages. For example there is no need to use high temperatures during syntheses process. The rise of nanotechnology stimulated new trends in sol-gel which holds considerable potential with its simplicity and possibility of giving the precursor different shapes before gelationoxide material that is generally hard to process is synthesized directly in desired shape. This work reports our recent progress in the elaboration of novel original sol-gel materials [1], [2], [3].
Synthesis and Evaluation of a Series of 1,2,4,5-Tetrazines for Bioorthogonal Conjugation (2011)

1,2,4,5-Tetrazines have been established as effective dienes for inverse electron demand [4 + 2] Diels-Alder cycloaddition reactions with strained alkenes for over 50 years. Recently, this reaction pair combination has been applied to bioorthogonal labeling and cell detection applications; however, to date, there has been no detailed examination and optimization of tetrazines for use in biological experiments. Here, we report the synthesis and characterization of 12 conjugatable tetrazines. The tetrazines were all synthesized in a similar fashion and were screened in parallel to identify candidates most ideally suited for biological studies. In depth follow-up studies revealed compounds with varying degrees of stability and reactivity that could each be useful in different bioorthogonal applications. One promising, highly stable, and water-soluble derivative was used in pretargeted cancer cell labeling studies, confirming its utility as a bioorthogonal moiety.
Expression and Functional Analysis of Recombinant Human Lactoferrin (1997)

Lactoferrin is a multifunctional iron-binding glycoprotein with potent antimicrobial properties. The protein is a prominent component of human milk, and also is found in most other exocrine secretions and in neutrophil granulocyte cells. Exploitation of the human protein as a natural antibiotic has not been feasible to date owing to the lack of a cost-effective means to produce sufficient quantities of purified lactoferrin. Previously, we reported the production of limited quantities of biologically active recombinant human lactoferrin in the filamentous fungus, Aspergillus oryzae. In the present study, we report a modification of this production system combined with a classical strain improvement program that has enabled production of levels of recombinant human lactoferrin in excess of 2 g/L. The protein was expressed in Aspergillus awamori as a glucoamylase fusion polypeptide that was secreted into the growth medium and processed to mature human lactoferrin by an endogenous KEX-2 peptidase. The recombinant protein retains full biological activity in terms of its ability to bind iron and human enterocyte receptors. Furthermore, the recombinant protein functions as a potent broad-spectrum antimicrobial protein.
Support arrangement for a flexible sound generating diaphragm (1983)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Robert L. Boyles, Samuel Polonsky; Support arrangement for a flexible sound generating diaphragm. J. Acoust. Soc. Am. 1 January 1983; 73 (1): 402. https://doi.org/10.1121/1.388717 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAcoustical Society of AmericaThe Journal of the Acoustical Society of America Search Advanced Search |Citation Search
An asymmetric subspace watermarking method for copyright protection (2005)

We present an asymmetric watermarking method for copyright protection that uses different matrix operations to embed and extract a watermark. It allows for the public release of all information, except the secret key. We investigate the conditions for a high detection probability, a low false positive probability, and the possibility of unauthorized users successfully hacking into our system. The robustness of our method is demonstrated by the simulation of various attacks.
Multiple Pregnancy-Associated Glycoproteins are Secreted by Day 100 Ovine Placental Tissue1 (1997)

Pregnancy-associated glycoprotein (PAG)-1 (PAG1) and pregnancy-specific protein B are either identical or closely related antigens released by trophoblast binucleate cells of placentas of cattle. Sheep and other ruminants produce similar products. There is evidence, however, that these antigens, which are related structurally to the pepsinogens and other aspartic proteinases, are not single gene products but members of an extensive family. Here, the sequential use of ammonium sulfate precipitation and Sepharose blue, anion-exchange, and cation-exchange chromatographies, as well as isoelectric elution from a Mono P column, has allowed several PAG1-related molecules to be purified from the medium after culture of explants from Day 100 sheep placentas. Each of these PAGs cross-reacted to a varying extent with a panel of three different anti-PAG1 antisera. Four of them, all of which were major secretory products of the placenta, were subjected to amino-terminal microsequencing. Although each was related to ovine (ov) PAG1, none was identical. Reverse transcription-polymerase chain reaction was then used to amplify PAG1-related cDNA from Day 100 placental RNA. Seven novel full-length cDNA, all distinct from ovPAG1, were identified from 25 cDNA selected for sequencing. Only two of these (ovPAG3 and ovPAG7) encoded polypeptides identical in sequence at their inferred amino termini to one of the PAGs (ovPAG65) purified from explant cultures. Even so, they were only 84% identical in overall sequence. The remaining five cDNA were unique. In situ hybridization analysis revealed that expression of ovPAG3 and ovPAG7, like that of ovPAG1, is confined to trophoblast binucleate cells. The data confirm that at Day 100 of pregnancy the ovine placenta produces many different PAGs, which differ considerably in sequence and immunological cross-reactivity.
Analysis of Multi-Criteria Fire Detection Data and Early Warning Fire Detection Prototype Selection (2000)

This report describes the analysis of Fire/Nuisance Source data and the selection of sensors for an early warning, multi-criteria, fire detection system for the Office of Naval Research (ONR) program on Damage Control: Automation for Reduced Manning (DC-ARM). In this work, the analysis of transient fire signatures is studied using a probabilistic neural network (PNN). Experiments are described to study the effects of various PNN training parameters and to determine the optimal sensor suite combination, which enables both early fire detection and high nuisance source rejection. Comparisons are made between the candidate sensor arrays, commercial fire detection systems, and sensor arrays proposed in previous reports Recommendations and directions for future research are also given.
Efficient analyte oxidation in an electrospray ion source using a porous flow-through electrode emitter (2004)

This article describes the components, operation, and use of a porous flow-through electrode emitter in an electrospray ion source. This emitter electrode geometry provided enhanced mass transport to the electrode surface to exploit the inherent electrochemistry of the electrospray process for efficient analyte oxidation at flow rates up to 800 microL/min. An upstream current loop in the electrospray source circuit, formed by a grounded contact to solution upstream of the emitter electrode, was utilized to increase the magnitude of the total current at the emitter electrode to overcome current limits to efficient oxidation. The resistance in this upstream current loop was altered to control the current and "dial-in" the extent of analyte oxidation, and thus, the abundance and nature of the oxidized analyte ions observed in the mass spectrum. The oxidation of reserpine to form a variety of products by multiple electron transfer reactions and oxidation of the ferroceneboronate derivative of pinacol to form the ES active radical cation were used to study and to illustrate the performance of this new emitter electrode design. Flow injection, continuous infusion, and on-line HPLC experiments were performed.
Improved single-user decoder metrics for two-stage detectors in DS-CDMA (2002)

Among the advantages of subtractive interference cancellation (IC), or multistage detectors for CDMA (code-division multiple-access) systems is that they facilitate feedback between the multiuser detection and decoding stages in a CDMA receiver. We propose modified branch metrics for the single-user Viterbi decoders used in conjunction with two-stage detectors for CDMA systems with long (random) spreading sequences. The modifications are based on modeling the residual multiple-access interference (RMAI) as conditionally Gaussian with time-dependent variance where the conditioning is on the time-varying user cross-correlations. A novel estimate of the variance of the total RMAI is presented, and put to use in the modified branch metrics. Significant performance gains are demonstrated over the Euclidean branch metric of the standard Viterbi decoder, and further improvements are discussed.
Cascaded light propagation volumes for real-time indirect illumination (2010)

This paper introduces a new scalable technique for approximating indirect illumination in fully dynamic scenes for real-time applications, such as video games. We use lattices and spherical harmonics to represent the spatial and angular distribution of light in the scene. Our technique does not require any precomputation and handles large scenes with nested lattices. It is primarily targeted at rendering single-bounce indirect illumination with occlusion, but can be extended to handle multiple bounces and participating media. We demonstrate that our method produces plausible results even when running on current game console hardware with a budget of only a few milliseconds for performing all computation steps for indirect lighting. We evaluate our technique and show it in combination with a variety of popular real-time rendering techniques.
A novel handover scheme to support small-cell users in a HetNet environment (2015)

Deployment of small cells is one of the most efficient solutions to improve the energy efficiency in mobile communication networks. However, small cell topology has a disadvantage such as frequent handovers of mobile user equipments (UEs). To solve this handover problem for small-cell users in a HetNet environment, we propose a novel handover scheme utilizing a cooperation-based cell clustering scheme for reducing handover overhead in core network (CN) and also signaling overhead among small cells. When a UE in active mode moves randomly, we can significantly reduce the handover ratio through the proposed scheme, compared with that of the conventional schemes. In particular, if the UE speed is 3 km/h, this ratio is approximately 0.07.
High Scale-Factor Stability Frequency-Modulated MEMS Gyroscope: 3-Axis Sensor and Integrated Electronics Design (2017)

This paper reports the developments toward an integrated, tri-axial, frequency-modulated, consumergrade, and microelectromechanical system (MEMS) gyroscope. A custom low-power (160 μA), low-phase-noise integrated circuit is designed specifically for frequencymodulated operation. Both yawand pitch-rate sensing systems are demonstrated by coupling the circuit with two novel micromachined structures fabricated with a 24-μmthick industrial process. In operation, both gyroscopes show a repeatable and stable scale factor, with less than 0.55% of part-to-part variability, obtained with no any calibration, and 35 ppm/°C of variability over a 25-70 °C temperature range.
Low-Dimensional Hyperthin FeS<sub>2</sub> Nanostructures for Efficient and Stable Hydrogen Evolution Electrocatalysis (2015)

We report a scalable, solution-processing method for synthesizing low-dimensional hyperthin FeS<sub>2</sub> nanostructures, and we show that 2D FeS<sub>2</sub> disc nanostructures are an efficient and stable hydrogen evolution electrocatalyst. By changing the Fe:S ratio in the precursor solution, we were able to preferentially synthesize either 1D wire or 2D disc nanostructures. The 2D FeS<sub>2</sub> disc structure has the highest electrocatalytic activity for the hydrogen evolution reaction, comparable to platinum in neutral pH conditions. Moreover, the ability of the FeS<sub>2</sub> nanostructures to generate hydrogen was confirmed by scanning electrochemical microscopy, and the 2D disc nanostructures were able to generate hydrogen for over 125 h.
A novel error observer-based adaptive output feedback approach for control of uncertain systems (2002)

We develop an adaptive output feedback control methodology for nonaffine in control of uncertain systems having full relative degree. Given a smooth reference trajectory, the objective is to design a controller that forces the system measurement to track it with bounded errors. A neural network with linear parameters is introduced as an adaptive signal. A simple linear observer is proposed to generate an error signal for the adaptive laws. Ultimate boundedness is shown through Lyapunov's direct method. Simulations of a nonlinear second-order system illustrate the theoretical results.
Communication—Sol-Gel Synthesized Magnesium Vanadium Oxide, Mg<sub>x</sub>V<sub>2</sub>O<sub>5</sub>· nH<sub>2</sub>O: The Role of Structural Mg<sup>2+</sup>on Battery Performance (2016)

Magnesium intercalated vanadium oxide xerogels, Mg<sub>0.1</sub>V<sub>2</sub>O<sub>5</sub> · 2.35H<sub>2</sub>O and Mg<sub>0.2</sub>V<sub>2</sub>O<sub>5</sub> · 2.46H<sub>2</sub>O were synthesized using an ion removal sol gel strategy. X-ray diffraction indicated lamellar ordering with turbostratic character. X-ray absorption spectroscopy indicated greater distortion of the vanadium-oxygen coordination environment in Mg<sub>0.2</sub>V<sub>2</sub>O<sub>5</sub> · 2.46H<sub>2</sub>O. Elemental analysis after cycling in Li<sup>+</sup> or Mg<sup>2+</sup> based electrolytes revealed that the magnesium content was unchanged, indicating structural Mg<sup>2+</sup> are retained. Furthermore, the Mg<sub>0.1</sub>V<sub>2</sub>O<sub>5</sub> · 2.35H<sub>2</sub>O material displayed high voltage, energy density, and discharge/charge efficiency, indicating promise as a cathode material for future magnesium based batteries.
Energy optimal management for prioritized distribution in smart grid (2016)

This paper designs an energy optimal management in smart grid infrastructure. As a way of assigning the prioritized optimal energy of the adjacent energy provider from the energy-requesting user, if there is a surplus of energy from the energy provider, the smart grid as being the closest to the user preferentially allocates the optimal energy to the requesting user in order to maximize the user satisfaction.
A real-time BIO-PCR assay for detection of<i>Ralstonia solanacearum</i>race 3, biovar 2, in asymptomatic potato tubers (2003)

Ralstonia solanacearum, the causal agent of brown rot of potato, can often be carried latently in seed potato tubers. We designed real-time PCR (polymerase chain reaction) primers and probe and a highly sensitive BIO-PCR assay for specific detection of the strains of race 3, biovar (bv.) 2 of R. solanacearum in asymptomatic potato tubers. The biovar-specific primers and probe reacted with all 17 strains of bv. 2 of R. solanacearum tested, including 12 from potato and 5 from geranium. None of the other 35 strains of R. solanacearum reacted, including 4 strains of bv. 1 from potato or the closely related blood disease bacterium from banana. None of 13 other bacteria reacted, including 5 Erwinia and 2 Clavibacter species from potato. Using undiluted potato tuber extract, inoculated with R. solanacearum bv. 2, as few as 30 cells/mL of extract could be detected. Two of 14 naturally infected potato tubers with no disease symptoms were positive by the newly described real-time BIO-PCR assay, whereas none were positive with a standard real-time PCR assay. This is the first report of the detection of R. solanacearum bv. 2 in asymptomatic, latently infected potato tubers by PCR. The real-time assay is very simple and much less time consuming than classical PCR.
Electrical Detection of Bio-molecular Recognition Using Insulated Gate Field Effect Transistors (2006)

A new concept of genetic field effect transistors (FET) is proposed for detection of specific binding of bio-molecules, which is in principle based on charge density change at the gate insulator. The electrical signals of the genetic FET were found to change after allele specific oligonucleotide hybridization, intercalation and primer extension. We demonstrated experimentally that the SNP genotyping could be achieved by the use of the genetic FETs in combination with allele specific extension reaction. Single base extension on the gate could be detected by the use of FET, which indicated possibility toward DNA sequencing. The genetic FET platform based on the direct transduction of oligonucleotide extension into electrical signal is suitable for a simple, accurate and inexpensive system for SNP typing in clinical diagnostics.
Emulating Metamaterial Anisotropy by Tapered Waveguides (2009)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text I. I. Smolyaninov, V. N. Smolyaninova, A. V. Kildishev, and V. M. Shalaev, "Emulating Metamaterial Anisotropy by Tapered Waveguides," in Conference on Lasers and Electro-Optics/International Quantum Electronics Conference, OSA Technical Digest (CD) (Optica Publishing Group, 2009), paper JThC2. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article