gebhart/patrepeval huggingface dataset:
Early Hemorrhage Growth in Patients With Intracerebral Hemorrhage (1997)

Substantial early hemorrhage growth in patients with intracerebral hemorrhage is common and is associated with neurological deterioration. Randomized treatment trials are needed to determine whether this early natural history of ongoing bleeding and frequent neurological deterioration can be improved.
Efficient α-Methylenationof Carbonyl Compounds in Ionic Liquids at Room Temperature (2008)

Americanae nace como un proyecto conjunto que surge dentro de la Red Europea de Información y Documentación sobre América Latina (REDIAL), y que ha afrontado la Biblioteca de la Agencia Española de Cooperación Internacional para el Desarrollo (AECID). Esta nueva biblioteca virtual hace más accesibles los libros digitales de tema americanista a los investigadores y usuarios interesados de cualquier parte del mundo.
On the use, and reuse, of polymers for the treatment of hydrocarbon contaminated water via a solid–liquid partitioning bioreactor (2008)

Aqueous environments contaminated with diesel components pose a threat to the native biota due to the intrinsically toxic nature of the many hydrocarbon compounds present. In the event of diesel being released into an aqueous environment it is imperative that the contaminant is recovered in a rapid manner to ensure the safety of aquatic organisms as well as to maintain desired water quality. The research presented in this study investigates the potential of polymeric sorbents to recover diesel from a contaminated aqueous source. Thermoplastic materials, such as styrene butadiene derived polymers, were shown to substantially reduce diesel levels in excess of 98% with 90% of this recoverable fraction being removed in less than 30 min. Recyclable materials, such as used automobile tires, were shown to obtain similar results with added potential benefit including lower cost and reuse of a waste material. The polymeric sorbents were also biologically regenerated and this was accomplished in a solid-liquid two-phase partitioning bioreactor, in which 65% of the initial diesel contamination was degraded within a 9 day period. The result of this work was the demonstration of a low cost, reusable remediation technology for the recovery, and destruction of diesel from aqueous environments.
Comparison of Gene Expression in Human Embryonic Stem Cells, hESC-Derived Mesenchymal Stem Cells and Human Mesenchymal Stem Cells (2011)

We present a strategy to identify developmental/differentiation and plasma membrane marker genes of the most primitive human Mesenchymal Stem Cells (hMSCs). Using sensitive and quantitative TaqMan Low Density Arrays (TLDA) methodology, we compared the expression of 381 genes in human Embryonic Stem Cells (hESCs), hESC-derived MSCs (hES-MSCs), and hMSCs. Analysis of differentiation genes indicated that hES-MSCs express the sarcomeric muscle lineage in addition to the classical mesenchymal lineages, suggesting they are more primitive than hMSCs. Transcript analysis of membrane antigens suggests that IL1R1(low), BMPR1B(low), FLT4(low), LRRC32(low), and CD34 may be good candidates for the detection and isolation of the most primitive hMSCs. The expression in hMSCs of cytokine genes, such as IL6, IL8, or FLT3LG, without expression of the corresponding receptor, suggests a role for these cytokines in the paracrine control of stem cell niches. Our database may be shared with other laboratories in order to explore the considerable clinical potential of hES-MSCs, which appear to represent an intermediate developmental stage between hESCs and hMSCs.
[Lower limb hemodynamic evaluation in patients with diabetic foot using 99mTc-methylene diphosphonate three-phase bone scintigraphy]. (2004)

(99m)Tc-MDP three-phase bone imaging can identify decreased uptake rate and R(m/t) in the diabetic foot, and the former index can be more sensitive and specific to define the hemodynamics in the diabetic foot. This technique may detect hemodynamic abnormity in early stage and greatly assist the diagnoses and treatment.
Human immunological response to mouse monoclonal antibodies in the treatment or diagnosis of malignant diseases (1988)

An overview of the literature is presented concerning the formation, detection, incidence and effect of the human immunoglobulin response on immunoscintigraphy. The following conclusions are drawn. The production of human anti-mouse antibodies (HAMAs) is associated with a diminished therapeutic response; adequate prevention of HAMA production is not yet possible; high HAMA titres give rise to rapid clearance of MoAb into the liver and marked reduction of tumour uptake which results in reduced image quality on immunoscintigraphy; alteration of antibody biodistribution is likely to be related to the in vivo formation of antibody-antibody complexes which could interfere with image quality when sequential imaging is carried out.
<title>Automated Optical Inspection Of Multilayer Printed Circuit Boards</title> (1980)

The Inspectron is an instrument which will perform an automatic optical inspection of the etched circuitry on the individual layers of a multilayer printed circuit board. The concept of this instrument is unique in that it does not compare the PCB under test with a master or with computer-stored data. Instead, as the board is optically scanned, a small area is re-imaged onto a detector array. The detector signals, after digitization, are fed into high-speed logic circuitry which is programmed to distinguish between the appearance of a good board and an error. An 8 x 10 inch board can be inspected for line width, line spacing, line breaks, excess copper, and voids in about a minute. The Inspectron can also inspect pads for completeness and ground planes for shorts.
Globally accessible names in named data networking (2013)

Information Centric Networking (ICN) paradigms aim at optimizing computer networks for information distribution. Named Data Networking (NDN) and its implementation CCNx propose a promising globally implementable ICN. Routing on names, however, may result in extremely large global routing tables. In this paper, we propose to confine the global routing table size by decoupling context-related names, such as domain names, from names routable within the network. By aggregating routable names to their topological location, the size of global routing tables decreases to the number of Autonomous Systems. Furthermore, mapping context-related names back to location-aggregated names using a directory service eases the process of sharing information on the ICN. The robustness of the network is further increased by employing dynamic multihoming without changing application names.
Estimating the Lyapunov-exponent spectrum from short time series of low precision (1991)

We propose a new method to compute Lyapunov exponents from limited experimental data. The method is tested on a variety of known model systems, and it is found that the algorithm can be used to obtain a reasonable Lyapunov-exponent spectrum from only 5000 data points with a precision of ${10}^{\mathrm{\ensuremath{-}}1}$ or ${10}^{\mathrm{\ensuremath{-}}2}$ in three- or four-dimensional phase space, or 10 000 data points in five-dimensional phase space. We also apply our algorithm to the daily-averaged data of surface temperature observed at two locations in the United States to quantitatively evaluate atmospheric predictability.
ARVISCOPE: Georeferenced Visualization of Dynamic Construction Processes in Three-Dimensional Outdoor Augmented Reality. (2008)

Construction processes can be conceived as systems of discrete, interdependent activities. Discrete Event Simulation (DES) has thus evolved as an effective tool to model operations that compete over available resources (personnel, material, and equipment). A DES model has to be verified and validated to ensure that it reflects a modeler’s intentions, and faithfully represents a real operation. 3D visualization is an effective means of achieving this, and facilitating the process of communicating and accrediting simulation results. Visualization of simulated operations has traditionally been achieved in Virtual Reality (VR). In order to create convincing VR animations, detailed information about an operation and the environment has to be obtained. The data must describe the simulated processes, and provide 3D CAD models of project resources, the facility under construction, and the surrounding terrain (Model Engineering). As the size and complexity of an operation increase, such data collection becomes an arduous, impractical, and often impossible task. This directly translates into loss of financial and human resources that could otherwise be productively used. In an effort to remedy this situation, this dissertation proposes an alternate approach of visualizing simulated operations using Augmented Reality (AR) to create mixed views of real existing jobsite facilities and virtual CAD models of construction resources. The application of AR in animating simulated operations has significant potential in reducing the aforementioned Model Engineering and data collection tasks, and at the same time can help in creating visually convincing output that can be effectively communicated. This dissertation presents the design, methodology, and development of ARVISCOPE, a general purpose AR animation authoring language, and ROVER, a mobile computing hardware framework. When used together, ARVISCOPE and ROVER can create three-dimensional AR animations of any length and complexity from the results of running DES models of engineering operations. ARVISCOPE takes advantage of advanced Global Positioning System (GPS) and orientation tracking technologies to accurately track a user’s spatial context, and georeferences superimposed 3D graphics in an augmented environment. In achieving the research objectives, major technical challenges such as accurate registration, automated occlusion handling, and dynamic scene construction and manipulation have been successfully identified and addressed.
Biomimetic Protein Nanoparticles Facilitate Enhanced Dendritic Cell Activation and Cross-Presentation (2013)

Many current cancer vaccine strategies suffer from the inability to mount a CD8 T cell response that is strong enough to overcome the low immunogenicity of tumors. Viruses naturally possess the sizes, geometries, and physical properties for which the immune system has evolved to recognize, and mimicking those properties with nanoparticles can produce robust platforms for vaccine design. Using the nonviral E2 core of pyruvate dehydrogenase, we have engineered a viral-mimicking vaccine platform capable of encapsulating dendritic cell (DC)-activating CpG molecules in an acid-releasable manner and displaying MHC I-restricted SIINFEKL peptide epitopes. Encapsulated CpG activated bone marrow-derived DCs at a 25-fold lower concentration in vitro when delivered with the E2 nanoparticle than with unbound CpG alone. Combining CpG and SIINFEKL within a single multifunctional particle induced ∼3-fold greater SIINFEKL display on MHC I by DCs over unbound peptide. Importantly, combining CpG and SIINFEKL to the E2 nanoparticle for simultaneous temporal and spatial delivery to DCs showed increased and prolonged CD8 T cell activation, relative to free peptide or peptide-bound E2. By codelivering peptide epitopes and CpG activator in a particle of optimal DC-uptake size, we demonstrate the ability of a noninfectious protein nanoparticle to mimic viral properties and facilitate enhanced DC activation and cross-presentation.
HOXA13 directly regulates <i>EphA6</i> and <i>EphA7</i> expression in the genital tubercle vascular endothelia (2007)

Hypospadias, a common defect affecting the growth and closure of the external genitalia, is often accompanied by gross enlargements of the genital tubercle (GT) vasculature. Because Hoxa13 homozygous mutant mice also exhibit hypospadias and GT vessel expansion, we examined whether genes playing a role in angiogenesis exhibit reduced expression in the GT. From this analysis, reductions in EphA6 and EphA7 were detected. Characterization of EphA6 and EphA7 expression in the GT confirmed colocalization with HOXA13 in the GT vascular endothelia. Analysis of the EphA6 and EphA7 promoter regions revealed a series of highly conserved cis-regulatory elements bound by HOXA13 with high affinity. GT chromatin immunoprecipitation confirmed that HOXA13 binds these gene-regulatory elements in vivo. In vitro, HOXA13 activates gene expression through the EphA6 and EphA7 gene-regulatory elements. Together these findings indicate that HOXA13 directly regulates EphA6 and EphA7 in the developing GT and identifies the GT vascular endothelia as a novel site for HOXA13-dependent expression of EphA6 and EphA7.
Stimuli‐Responsive Polymersomes as Nanocarriers for Drug and Gene Delivery (2008)

Polymeric formulations (micelles, vesicles etc.) have emerged as versatile drug carriers due to their increased stability, site specificity, blood circulation resistance and thus overall potential therapeutic effects compared to liposomes. Furthermore, stimuli-responsive systems have been developed whose properties change after applying certain external triggers. Polymersomes are mainly composed of amphiphilic block copolymers that are held together in water due to strong physical interactions between the insoluble hydrophobic blocks, thus forming a bilayer morphology or, in the case of triblock copolymers, a bilayer-like morphology. Formation and destabilization of these assemblies is a consequence of external stimuli (temperature, pH, oxidation/reduction conditions etc.). This review focuses on recent developments concerning stimuli- responsive polymersomes made of amphiphilic block copolymers and their potential applications within the biomedical field.
A monolithic optical front-end for soft-decision LDPC decoders (2012)

In this paper, we propose a monolithic optical front-end for soft-decision low-density parity-check (LDPC) decoders based on 112 Gb/s polarization division multiplexed quadrature shift keying (PM-QPSK) coherent detection. The novel front-end is a low complexity and low cost solution with a performance improvement of 6.4 dB over system without the use of coding. The front-end also outperforms the conventional RS(255,239) based codes by 1.3 dB at the BER of 10<sup>-8</sup>.
Arterial properties of early hypertension. (1991)

In addition to high blood pressure, hypertension is characterised by metabolic and cardiovascular abnormalities, including decreased arterial compliance. To evaluate arterial involvement in early hypertension, we have employed a technique that analyses the arterial pulse wave contour to separately quantify proximal compliance (aorta and large arteries) and distal compliance (small arteries and arterioles). Proximal compliance was 24% lower in patients with borderline (diastolic BP 90-99 mmHg, n = 22) and 33% lower in patients with established (n = 19) hypertension than in normals (n = 15); distal compliance was 58% and 61% lower. These differences were not age-dependent, for in 27 age-matched pairs, proximal and distal compliances were 22% (P less than 0.01) and 55% (P less than 0.01) lower in hypertensives (diastolic BP greater than or equal to 95 mmHg) than in normotensives. Moreover, independent of BP or age, both proximal (P less than 0.05) and distal (P less than 0.01) compliance values were significantly lower in subjects with a family history of hypertension than in those without. Proximal compliance correlated inversely with indices of BP variability and heart work measured by automated whole-day blood pressure monitoring. Thus, changes in the elastic properties of the distal arterial circulation, reflected by decreased compliance, occur at the initiation of hypertension and may be an early diagnostic marker. Low proximal compliance appears to be associated with established hypertension, and might be a determinant of cardiovascular prognosis.
Composition and phase dependence of the intrinsic and extrinsic piezoelectric activity of domain engineered (1−x)Pb(Mg1/3Nb2/3)O3−xPbTiO3 crystals (2010)

The piezoelectric response of [001] poled domain engineered (1-x)Pb(Mg(13)Nb(23))O(3)-xPbTiO(3) (PMN-PT) crystals was investigated as a function of composition and phase using Rayleigh analysis. The results revealed that the intrinsic (reversible) contribution plays a dominant role in the high piezoelectric activity for PMN-PT crystals. The intrinsic piezoelectric response of the monoclinic (M(C)) PMN-xPT crystals, 0.31</=x</=0.35, exhibited peak values for compositions close to R-M(C) and M(C)-T phase boundaries, however, being less than 2000 pCN. In the rhombohedral phase region, x</=0.30, the intrinsic piezoelectric response was found to increase as the composition approached the rhombohedral-monoclinic (R-M(C)) phase boundary. The maximum piezoelectric response was observed in rhombohedral PMN-0.30PT crystals, being on the order of 2500 pCN. This ultrahigh piezoelectric response was determined to be related to the high shear piezoelectric activity of single domain state, corresponding to an ease in polarization rotation, for compositions close to a morphotropic phase boundary (MPB). The role of monoclinic phase is only to form a MPB with R phase, but not directly contribute to the ultrahigh piezoelectric activity in rhombohedral PMN-0.30PT crystals. The extrinsic contribution to piezoelectric activity was found to be less than 5% for the compositions away from R-M(C) and M(C)-T phase boundaries, due to a stable domain engineered structure. As the composition approached MPBs, the extrinsic contribution increased slightly (<10%), due to the enhanced motion of phase boundaries.
Limitations of the tunability of dual-crystal optical parametric oscillators (2007)

We demonstrate what is believed to be the first continuous-wave dual-crystal optical parametric oscillator (D-OPO) for generation of waves with a frequency difference of some terahertz. It is based on two magnesium-doped periodically poled lithium niobate crystals pumped with near-infrared light at 1030 nm. By changing the temperature difference of the crystals we achieve a difference-frequency tuning. This ranges from an initially unexpected lower threshold of 1.3 THz up to higher frequencies. The linewidth of the considered signal waves is smaller than 5 GHz. Smaller difference frequencies were not achievable. Our model, describing the dual-crystal parametric gain, explains the observed lower tuning limit by showing that the assumption of independent oscillation conditions in a D-OPO is not necessarily valid.
Preparation of Cyanoalkynes: 3‐Phenyl‐2‐Propynenitrile (2003)

Abstract Preparation of cyanoalkynes: 3‐phenyl‐2‐propynenitrile product: 3‐phenyl‐2‐propynenitrile product: n‐C 5 CCCN product: n‐C 6 CCCN
Optical excitation and detection of vapor bubbles around plasmonic nanoparticles (2009)

Laser-induced generation of the vapor bubbles in water around plasmonic nanoparticles was experimentally studied with optical scattering methods. Nanoparticle-generated bubbles temporally and spatially localize laser-induced thermal field and also amplify optical scattering relatively to that of gold nanoparticles. Bubble lifetimes and threshold fluencies were determined as functions of the laser (pulse duration, fluence, inter-pulse interval), nanoparticle (size, shape, aggregation state) and sample chamber parameters so to optimize bubble generation around plasmonic nanoparticles. Nanoparticle-generated bubbles are suggested as nano-scaled optical sensors and sources of localized thermal and mechanical impact.
ChemInform Abstract: SYNTHESIS AND BIOLOGICAL ACTIVITY OF SOME 3‐(PYRAZOL‐1′‐YL)INDAZOLE DERIVATIVES (1985)

The synthesis of some 3-(pyrazol-1'-yl)indazole derivatives is reported. The synthesized compounds were subjected to in vitro antimicrobial screenings. Only two of the tested compounds showed a mild activity at high concentrations.
All in one Intelligent Safety System for Women Security (2015)

According to the reports of WHO, NCRB-social-government organization 35%Women all over the world are facing a lot of unethical physical harassment in public places such as railway-bus stands, foot paths etc. In this paper the authors have reviewed of various existing systems on women security. The authors have felt a need of advanced women security system to provides the safety measure in public places as well as travelling alone through public transports (school buses, company vehicle etc). This paper proposed a new model for the women security in public places which aims to provide the 100% safe environment.
Development of contrast enhancing agents in magnetic resonance imaging. (1989)

Magnetic Resonance Imaging (MRI) is a powerful new diagnostic tool in medicine. In MRI there is a great need to improve the specific identification of different tissues i.e. to enhance the contrast between them. This review tries to cover most of the approaches known for solving this problem.
Perspective—Commercializing Lithium Sulfur Batteries: Are We Doing the Right Research? (2017)

A picture of the challenges faced by the lithium-sulfur technology and the activities pursued by the research community to solve them is synthesized based on 1992 scientific articles. It is shown that, against its own advice of adopting a balanced approach to development, the community has instead focused work on the cathode. To help direct future work, key areas of neglected research are highlighted, including cell operation studies, modelling, anode, electrolyte and production methods, as well as development goals for real world target applications such as high altitude unmanned aerial vehicles.
Methyl 3-cyclopropyl-3-oxopropanoate in the synthesis of heterocycles having a cyclopropyl substituent (2010)

Reactions of methyl 3-cyclopropyl-3-oxopropanoate with chloroacetone and ammonia, benzaldehyde and ammonia, and benzoquinone gave, respectively, methyl 2-cyclopropyl-5-methyl-1H-pyrrole-3-carboxylate, dimethyl 2,6-dicyclopropyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate, and methyl 2-cyclopropyl-5-hydroxy-1-benzofuran-3-carboxylate. Cyclization of methyl 3-cyclopropyl-3-oxopropanoate with ethyl chloro(arylhydrazono)ethanoates and other halohydrazones led to the formation of 3-substituted 1-aryl-5-cyclopropyl-1H-pyrazole-4-carboxylic acids, and 5-cyclopropyl-1-(quinolin-5-yl)-1H-1,2,3-triazole-4-carboxylic acid was obtained by reaction of the title compound with 5-azidoquinolines.
Ocelot/HyPE (2014)

The past years saw the emergence of highly heterogeneous server architectures that feature multiple accelerators in addition to the main processor. Efficiently exploiting these systems for data processing is a challenging research problem that comprises many facets, including how to find an optimal operator placement strategy, how to estimate runtime costs across different hardware architectures, and how to manage the code and maintenance blowup caused by having to support multiple architectures. In prior work, we already discussed solutions to some of these problems: First, we showed that specifying operators in a hardware-oblivious way can prevent code blowup while still maintaining competitive performance when supporting multiple architectures. Second, we presented learning cost functions and several heuristics to efficiently place operators across all available devices. In this demonstration, we provide further insights into this line of work by presenting our combined system Ocelot/HyPE. Our system integrates a hardware-oblivious data processing engine with a learning query optimizer for placement decisions, resulting in a highly adaptive DBMS that is specifically tailored towards heterogeneous hardware environments.