gebhart/patrepeval huggingface dataset:
A new similarity criterion for retinal image registration (2002)

Registration methods invariably demand the evaluation of similarity between image areas using criteria based on the maintenance of pixel relative intensities. Because of the severe brightness changes in retinal images, intensity dependent similarity measures are often unable to produce useful registration results. The main purpose of this paper is the presentation of a new similarity evaluation criterion, prepared to overcome the problems raised by important brightness modifications in the images to register. The new criterion is based on the detection of edge point localizations, which are used to assess the correspondence of the compared areas. Some attention was also dedicated to the measure calculation process, and, as an ultimate result, a two-stage implementation was adopted. The values generated by the similarity measure determination step are later used by two registration algorithms prepared to compensate for distinct geometric misalignments between the images.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Nonlinear Dynamics of Intracellular Methylene Blue During Light Activation of Cell Cultures (1997)

Methylene blue (MB+) is a well-known dye in medicine and has been discussed as an easily applicable drug for topical treatment in photodynamic therapy (PDT). Methylene blue can potentially be used as a redox indicator to detect the important redox reactions that are induced during PDT. The kinetics of this process was analyzed on a subcellular level with confocal laser scanning microscopy. BKEz-7 endothelial cells were incubated 4 h with 1 microM MB+. The fluorescence dynamics of MB+ during irradiation with 633 nm light was observed with subcellular resolution. Images were acquired at 0.5 s intervals (frame rate 1 image/0.5 s). Fluorescence was observed in the red channel of the laser scanning microscope. Synchronously, the phase-contrast image was visualized with the green channel. Morphological changes could therefore be correlated with the dynamics of MB+. In addition, the light-dose-dependent phototoxicity at 633 nm irradiation was determined by viable cell counting. After an induction period (phase I), fast fluorescent spikes could be observed in the whole cytoplasm, which decayed with a time constant of about 20 s (phase II), followed by a period of nearly constant fluorescence intensity (phase III) and exponential photobleaching (phase IV). Phase II exhibits highly nonlinear kinetics, which is hypothesized to correlate probably with a nonlinear quantal production of reactive oxygen species (ROS). Morphological cell changes were not observed during phase II. During phase III, a pycnotic cell nucleus developed. From the determination of viable cells we can conclude that a light dose applied within phase II was only sublethal in correlation with morphological observations. Overproduction of ROS leading finally to cell killing during phases III and IV is discussed.
Protection of MP3 Music Files Using Digital Rights Management and Symmetric Ciphering (2006)

This paper presents part the work conducted on the 1ST FP6 MediaNet Integrated Project to implement a Media Center solution integrated in a home netwok environment. This Media Center solution - which was called MediaBox $allowed the user to access from his/her home to DRM-protected music from online digital music stores. The paper describes the specific work that was conducted in the protection of the MP3 music files and on the specific mechanisms of the DRM platform. These DRM mechanisms allow both the protection of the music file as well as the conditional music rendering at the end-user side, on a client-side platform - the MediaBox
Pulsed proton-beam annealing of Ir and Ir<i>x</i>V100−<i>x</i> thin films on silicon (1985)

A pulsed proton beam was used to anneal Ir and IrxV100−x thin films deposited on Si single crystals. Compound phases were produced by local melting of the metal-Si interface. Phase identification was carried out by x-ray diffraction; while component distribution was determined by Auger electron spectroscopy and Rutherford backscattering spectrometry. The morphology of the silicide layers was examined using transmission electron microscopy; and Schottky barrier heights were determined by current-voltage measurements. At intermediate deposited energy densities (∼0.5 J/cm2) a controlled interfacial reaction was observed. In the case of Ir/Si, amorphous IrSi as well as polycrystalline IrSi and Ir2Si3 was detected in the reacted region. For the codeposited IrxV100−x film, with x=80 and 50, the interfacial layer reacting with the Si substrate maintained the Ir : V ratio of the as-deposited film. This is in contrast to the case of furnace annealing where preferred accumulation of Ir is observed.
Advanced sound capturing method with adaptive noise reduction system for broadcasting multicopters (2015)

A multicopter is now becoming a crucial part in the broadcasting industry for capturing videos. When they are not able to reach places, men can control multicopters and take desired videos. However, there still exist many problems in capturing sound because the multicopter is often placed far from the sound source and the sound of the propellers interferes with the recording target sound. Capturing high quality sound is indispensable to fulfill consumers' needs to have high quality videos. Nonetheless, there are not many studies of capturing target sound while reducing propellers' sound. Therefore, it is inevitable to suggest applicable methods to reduce noise to get better sound to be transmitted. This paper proposes experimental methods of capturing sound through adaptive signal processing for decreasing propellers' sound.
Fe<sub>3</sub>C-based oxygen reduction catalysts: synthesis, hollow spherical structures and applications in fuel cells (2014)

A new type of Fe<sub>3</sub>C-based ORR catalyst is reported including synthesis, tailored nanostructures, activities and active sites as well as fuel cell demonstration.
Synthesis, Characterization, and Fluorescence Behavior of Twisted and Planar B<sub>2</sub>N<sub>2</sub>-Quaterphenyl Analogues (2007)

A series of planar and twisted heteroaromatic quaterphenyl analogues containing BN ring linkages has been synthesized using primarily difunctional Lewis acidic diborabiphenyl moieties as molecular cores. Crystal structure analyses indicated the presence of large twist angles between adjacent aromatic rings in 1 and 3, which were also observed to possess nonfluorescent behavior due to a lack of molecular rigidity and insufficient B=N character in the excited state. In contrast, the incorporation of one or two bridging ethylene groups between the adjacent rings (installed via an ethynyl cycloisomerization) was found to afford planar phenanthrene or pyrene moieties, which resulted in weak fluorescence behavior (Phi F = 0.02-0.16) for the n-Bu and Ph derivatives 5-12. Emission colors ranged from green (lambda em = 521 nm) to red (lambda em = 630 nm) and depended primarily on the conformation (2,2'- vs 4,4'-), the extent of chromophore conjugation (phenanthrene vs pyrene), and the type of exocyclic substituent present (n-Bu vs Ph). Communication between the two phenanthrene or pyrene moieties was observed in some cases, which was characterized by bathochromically shifted emission bands relative to that of monomeric phenanthrene or pyrene species. Unique excited-state dimer (excimer) fluorescence was observed for the 2,2'-isomer 8, which was characterized by broad, low-energy emission bands bathochromically shifted from that of the corresponding monomer.
Protein identifications of O'Farrell two-dimensional gels: locations of 81 Escherichia coli proteins (1980)

The two-dimensional gel electrophoresis method of P. H. O'Farrell readily resolves approximately 1,000 proteins from whole-cell homogenates. We have found that the location of most individual proteins is sufficiently reproducible and precise to permit different laboratories to exchange information about them. We present the location of 81 Escherichia coli structural proteins, binding proteins, enzymes, and factors, identified with the aid of purified proteins supplied to us by many investigators.
低头看看指尖,这些按键你会用吗?——善用键盘的快捷键和组合键 (2008)

作为我们最重要输出工具——键盘,你真的能用得很好吗?路人甲:什么?区区一个键盘我们还不会用吗?不就是盲打、五笔之类吗?小case!错!不仅仅是这些,虽然十几年来键盘没有太大的结构变化,最大的用途还是用来进行文字的输入,但是,它不再是唯一的用途,合理的使用快捷键和组合键能更好的提高电脑的易用性和使用效率。
Human Digital Twin for Fitness Management (2020)

Our research work describes a team of human Digital Twins (DTs), each tracking fitness-related measurements describing an athlete's behavior in consecutive days (e.g. food income, activity, sleep). After collecting enough measurements, the DT firstly predicts the physical twin performance during training and, in case of non-optimal result, it suggests modifications in the athlete's behavior. The athlete's team is integrated into SmartFit, a software framework for supporting trainers and coaches in monitoring and manage athletes' fitness activity and results. Through IoT sensors embedded in wearable devices and applications for manual logging (e.g. mood, food income), SmartFit continuously captures measurements, initially treated as the dynamic data describing the current physical twins' status. Dynamic data allows adapting each DT's status and triggering the DT's predictions and suggestions. The analyzed measurements are stored as the historical data, further processed by the DT to update (increase) its knowledge and ability to provide reliable predictions. Results show that, thanks to the team of DTs, SmartFit computes trustable predictions of the physical twins' conditions and produces understandable suggestions which can be used by trainers to trigger optimization actions in the athletes' behavior. Though applied in the sport context, SmartFit can be easily adapted to other monitoring tasks.
Grouped Spatial-Temporal Aggregation for Efficient Action Recognition (2019)

Temporal reasoning is an important aspect of video analysis. 3D CNN shows good performance by exploring spatial-temporal features jointly in an unconstrained way, but it also increases the computational cost a lot. Previous works try to reduce the complexity by decoupling the spatial and temporal filters. In this paper, we propose a novel decomposition method that decomposes the feature channels into spatial and temporal groups in parallel. This decomposition can make two groups focus on static and dynamic cues separately. We call this grouped spatial-temporal aggregation (GST). This decomposition is more parameter-efficient and enables us to quantitatively analyze the contributions of spatial and temporal features in different layers. We verify our model on several action recognition tasks that require temporal reasoning and show its effectiveness.
Technical Training Programs (1986)

There is a definite reorientation of the work force in this country. The move to a more technical society has been widely forecast, and despite the valleys and peaks driven by fluctuation in economy, the movement is sure and pervasive. Both professional and technician levels of the engineering community must work smarter. For most it means never quite catching up with the level of knowledge available in a given field of work, from routine construction to complicated communication techniques. 'In-house' training or continuing education must be recognized as an essential element of doing business. Many companies have already recognized this requirement, but are continually searching for more streamlined technology transfer methods. Companies must be aware of current practice for developing and implementing employee training and its effectiveness.
Genome‐Wide DNA Methylation Study Identifies Significant Epigenomic Changes in Osteoarthritic Cartilage (2014)

Objective To perform a genome‐wide DNA methylation study to identify DNA methylation changes in osteoarthritic (OA) cartilage tissue. Methods The contribution of differentially methylated genes to OA pathogenesis was assessed by bioinformatic analysis, gene expression analysis, and histopathologic severity correlation. Genome‐wide DNA methylation profiling of >485,000 methylation sites was performed on eroded and intact cartilage from within the same joint of 24 patients undergoing hip arthroplasty for OA. Genes with differentially methylated CpG sites were analyzed to identify overrepresented gene ontologies, pathways, and upstream regulators. The messenger RNA expression of a subset of differentially methylated genes was analyzed by reverse transcription–polymerase chain reaction. Histopathology was graded by modified Mankin score and correlated with DNA methylation. Results We identified 550 differentially methylated sites in OA. Most (69%) were hypomethylated and enriched among gene enhancers. We found differential methylation in genes with prior links to OA, including RUNX1 , RUNX2 , DLX5 , FURIN , HTRA1 , FGFR2 , NFATC1 , SNCAIP , and COL11A2 . Among these, RUNX1 , HTRA1 , FGFR2 , and COL11A2 were also differentially expressed. Furthermore, we found differential methylation in approximately one‐third of known OA susceptibility genes. Among differentially methylated genes, upstream regulator analysis showed enrichment of TGFB1 ( P = 4.40 × 10 −5 ) and several microRNAs including miR‐128 ( P = 4.48 × 10 −13 ), miR‐27a ( P = 4.15 × 10 −12 ), and miR‐9 ( P = 9.20 × 10 −10 ). Finally, we identified strong correlations between 20 CpG sites and the histologic Mankin score in OA. Conclusion Our data implicate epigenetic dysregulation of a host of genes and pathways in OA, including a number of OA susceptibility genes. Furthermore, we identified correlations between CpG methylation and histologic severity in OA.
2007 headset preference survey (2007)

Subtitle: Electronic ANR: 1 Bose, 2 Lightspeed, 3 Telex, 4 David Clark, 5 Sennheiser. Nonelectronic PNR: 1 David Clark, 2 Telex. In ANR division Telex takes 3rd with improved scores across the board, swapping places with David Clark, now 4th. ANR popularity continues to rise. 1296 evaluations, 12% return.
Effect of L-Ergothioneine on the metabolic plasma profile of the RUPP rat model of pre-eclampsia (2020)

L-Ergothioneine may help preserve mitochondrial function by increasing antioxidant levels, and reducing inflammatory responses associated with pre-eclampsia. This study shows the potential of L-Ergothioneine as a treatment for pre-eclampsia.
Elastase activity on sputum neutrophils correlates with severity of lung disease in cystic fibrosis (2018)

Neutrophil elastase (NE) is a key risk factor for severity of cystic fibrosis (CF) lung disease. Recent studies identified increased NE activity on the surface of airway neutrophils from CF-like mice and patients with CF. However, the role of surface-bound NE in CF lung disease remains unknown. We determined the relationship between surface-bound NE activity and severity of lung disease in CF.Surface-bound NE activity was measured on sputum neutrophils from 35 CF patients and eight healthy controls using novel lipidated Förster resonance energy transfer reporters and correlated with free NE activity, neutrophil counts, interleukin-8, myeloperoxidase and antiproteases in sputum supernatant, and with lung function parameters.Surface-bound NE activity was increased in CF compared to healthy controls (p<0.01) and correlated with free NE activity (p<0.05) and other inflammation markers (p<0.001). Surface-bound and free NE activity correlated with forced expiratory volume in 1 s % predicted (p<0.01 and p<0.05), but only surface-bound NE activity correlated with plethysmographic functional residual capacity % pred (p<0.01) in patients with CF.We demonstrate that surface-bound NE activity on airway neutrophils correlates with severity of lung disease in patients with CF. Our results suggest that surface-bound NE activity may play an important role in the pathogenesis and serve as novel biomarker in CF lung disease.
SEPARATION OF FISCHER-TROPSCH WAX PRODUCTS FROM ULTRAFINE IRON CATALYST PARTICLES (2004)

In this reporting period, a fundamental filtration study was continued to investigate the separation of Fischer-Tropsch Synthesis (FTS) liquids from iron-based catalyst particles. The overall focus of the program is with slurry-phase FTS in slurry bubble column reactor systems. Hydrocarbon products must be separated from catalyst particles before being removed from the reactor system. An efficient wax product/catalyst separation system is a key factor for optimizing operating costs for iron-based slurry-phase FTS. Previous work has focused on catalyst particle attrition and the formation of ultra-fine iron carbide and/or carbon particles. With the current study, we are investigating how the filtration properties are affected by these chemical and physical changes of the catalyst slurry during activation/synthesis. The shakedown phase of the pilot-scale filtration platform was completed at the end of the last reporting period. A study of various molecular weight waxes was initiated to determine the effect of wax physical properties on the permeation rate without catalyst present. As expected, the permeation flux was inversely proportional to the nominal average molecular weight of the polyethylene wax. Even without catalyst particles present in the filtrate, the filtration membranes experience fouling during an induction period on the order of days on-line. Another long-term filtration test was initiated using a batch of iron catalyst that was previously activated with CO to form iron carbide in a separate continuous stirred tank reactor (CSTR) system. The permeation flux stabilized more rapidly than that experienced with unactivated catalyst tests.
Risk Assessments: A Weighted Score Approach to Improving Risk Management Decisions (2020)

Increases in security breaches have resulted in the need for organizations to identify, mitigate, and eliminate potential risks more than ever before. One of the most effective ways to heighten security awareness and reduce its risks is to conduct a thorough risk assessment and consistently audit identified risks. The subjective nature of risk assessments and the lack of a standardized rating scale, however, can produce various outcomes and calculations, leading to an inconsistent analysis of the identified risks. The unstructured risk assessment models and frameworks may lead some organizations to contribute more resources to risks that are of lesser importance than others. This paper will propose a new method to improve the standard risk assessment models. An original risk assessment calculation method will be introduced and analyzed using DeLone and Mclean's IS Success Model.
Learning Object Grasping for Soft Robot Hands (2018)

We present a three-dimensional deep convolutional neural network (3D CNN) approach for grasping unknown objects with soft hands. Soft hands are compliant and capable of handling uncertainty in sensing and actuation, but come at the cost of unpredictable deformation of the soft fingers. Traditional model-driven grasping approaches, which assume known models for objects, robot hands, and stable grasps with expected contacts, are inapplicable to such soft hands, since predicting contact points between objects and soft hands is not straightforward. Our solution adopts a deep CNN approach to find good caging grasps for previously unseen objects by learning effective features and a classifier from point cloud data. Unlike recent CNN models applied to robotic grasping which have been trained on 2D or 2.5D images and limited to a fixed top grasping direction, we exploit the power of a 3D CNN model to estimate suitable grasp poses from multiple grasping directions (top and side directions) and wrist orientations, which has great potential for geometry-related robotic tasks. Our soft hands guided by the 3D CNN algorithm show 87% successful grasping on previously unseen objects. A set of comparative evaluations shows the robustness of our approach with respect to noise and occlusions.
Reishi,<i>Ganoderma lucidum</i>and<i>Ganoderma tsugae</i>: Bioactive substances and medicinal effects (1995)

(1995). Reishi, Ganoderma lucidum and Ganoderma tsugae: Bioactive substances and medicinal effects. Food Reviews International: Vol. 11, Mushrooms: The Versatile Fungus-Food and Medicinal Properties, pp. 151-166.
Changes in the Localization of the Rat Canalicular Conjugate Export Pump Mrp2 in Phalloidin–Induced Cholestasis (1999)

Administration of phalloidin, one of the toxic peptides of the mushroom Amanita phalloides, leads to rapid and sustained cholestasis in rats. Although attributed to the interaction of phalloidin with microfilaments, the events leading to cholestasis are incompletely understood. The adenosine triphosphate (ATP)-dependent, apical conjugate export pump, termed multidrug resistance protein 2 (Mrp2) or canalicular multispecific organic anion transporter, is the major driving force for bile salt-independent bile flow. We investigated the role of Mrp2 in phalloidin-induced cholestasis. Bile flow decreased to 53% and 31% of control at 15 and 30 minutes after phalloidin (0.5 mg/kg), respectively. Mrp2-mediated [3H]leukotriene excretion into bile during the initial 45 minutes was reduced to 44% of control when [3H]LTC4 was injected 15 minutes after phalloidin treatment. Mrp2 was progressively lost from the hepatocyte canalicular membrane and detected predominantly on intracellular membrane structures together with other canalicular proteins including P-glycoproteins, ecto-ATPase, and dipeptidyl-peptidase IV. By contrast, structures involved in intercellular adhesion (zonula occludens, zonula adhaerens, and desmosomes) as well as intermediate filaments of the cytokeratin type appeared largely unaffected within 30 minutes after phalloidin. In line with the immunofluorescence analysis, immunoblots indicated a loss of Mrp2 and P-glycoproteins from the canalicular membrane and a 3- and 4.6-fold increase of these transport proteins in the microsomal fraction, respectively. Our results indicate that phalloidin induces marked alterations of the hepatocyte canalicular architecture and a loss of Mrp2 together with other proteins from the canalicular membrane. The resulting cholestasis can therefore be explained in part by the loss of export pumps, including Mrp2, from the canalicular membrane.
Understanding the Formation of Salt-Inclusion Phases: An Enhanced Flux Growth Method for the Targeted Synthesis of Salt-Inclusion Cesium Halide Uranyl Silicates (2016)

Salt-inclusion compounds (SICs) are known for their structural diversity and their potential applications, including luminescence and radioactive waste storage forms. Currently, the majority of salt-inclusion phases are grown serendipitously and the targeted growth of SICs has met with only moderate success. We report an enhanced flux growth method for the targeted growth of SICs. Specifically, the use of (1) metal halide reagents and (2) reactions with small surface area to volume ratios are found to favor the growth of salt-inclusion compounds over pure oxides and thus enable a more targeted synthetic route for their preparation. The Cs-X-U-Si-O (X = F, Cl) pentanary phase space is used as a model system to demonstrate the generality of this enhanced flux method approach. Single crystals of four new salt-inclusion uranyl silicates, [Cs3F][(UO2)(Si4O10)], [Cs2Cs5F][(UO2)2(Si6O17)], [Cs9Cs6Cl][(UO2)7(Si6O17)2(Si4O12)], and [Cs2Cs5F][(UO2)3(Si2O7)2], were grown using this enhanced flux growth method. A detailed discussion of the factors that favor salt-inclusion phases during synthesis and why specifically uranyl silicates make excellent frameworks for salt-inclusion phases is given.