gebhart/patrepeval huggingface dataset:
Experimental investigation of passive infrared ice detection for helicopter applications (1991)

A technique is proposed to remotely detect rotor icing on helicopters. Using passive infrared (IR) thermometry, it is possible to detect the warming caused by latent heat released as supercooled water freezes. During icing, the ice accretion region on the blade leading edge will be warmer than the uniced trailing edge, resulting in a chordwise temperature profile characteristic of icing. Preliminary tests were conducted on a static model in the NASA Icing Research Tunnel for a variety of wet (glaze) and dry (rime) ice conditions. The characteristic chordwise temperature profiles were observed with an IR thermal video system and confirmed with thermocouple measurements. A prototype detector system was built consisting of a single point IR pyrometer. Experiments were run on a small scale rotor model. Again, the characteristic chordwise temperature profiles were observed during icing, and the IR system was able to remotely detect icing. Based on the static and subscale rotor tests, the passive IR technique is promising for rotor ice detection.
<title>Refinement of printer transformations using weighted regression</title> (1996)

Printer characterization and color correction are often complex transformations, and are derived with numerous measurements or printer models. There are many sources of errors in these transforms, including inaccuracies in lookup table approximation, errors in the printer model, noise in the data, and spatial and temporal non-uniformities in the printer. A method is proposed to increase the accuracy of an existing printer transform with a relatively small number of refinement measurements. A weighted linear least-squares regression technique is used to improve the fit of the printer response to the refinement data. The hypothesis is that a locally linear transform can adequately capture the difference between the true printer transform and its approximation. In contrast to existing approaches that only refine the individual C, M, Y, K responses, the proposed method attempts to account for cross-colorant interactions by using mixed colors in the refinement set. Furthermore, the refinement data is not restricted to lying on a regular grid, and can be freely chosen based on any a priori knowledge about the printer. The approach is tested for two related transforms: the characterization transform which maps CMYK to L*a*b*; and its inverse, the color correction transform that maps L*a*b* to CMYK. Results show an improvement in transform accuracy with a relatively small number of measurements.
A study of tubular braided structure with negative Poisson’s ratio behavior (2017)

Textile structures with negative Poisson’s ratio (PR) behavior are called auxetic textile structures. They have received increasing attention in recent years and have been designed and fabricated through spinning, knitting, weaving and non-woven methods. However, auxetic textile structures fabricated using braiding method have not been reported so far. This paper reported a novel type of auxetic braided structure based on a helical structural arrangement. The geometry of the structure and its deformation mechanism were first introduced and described. Then a special manufacturing process was developed by the modification of commonly used tubular braiding technology. Various auxetic braids were fabricated with different structural parameters and yarns and tested under uniaxial extension conditions. The results showed that all manufactured braids exhibited high negative PR behavior and maintained this behavior until the fracture of the component wrap yarn. Among three structural parameters discussed, namely wrap angle, braiding angle and braiding yarn diameter, the wrap angle had more effects on the tensile properties of auxetic braided structure than the other two parameters. The success of fabricating auxetic braids with commercially available yarns in this study provides an alternative way to manufacture auxetics from positive PR materials.
Isolation and Initial Characterization of Constitutive Nitrate Reductase-Deficient Mutants NR328 and NR345 of Soybean (<i>Glycine max</i>) (1986)

Two nitrate reductase deficient mutants of soybean (Glycine max [L.] Merr. cv Bragg) were isolated from approximately 10,000 M(2) seedlings, using a direct enzymic assay in microtiter plates. Stable inheritance of NR345 and NR328 phenotypes has been demonstrated through to the M(5) generation. Both mutants were affected in constitutive nitrate reductase activity. Assayable activities of cNR in nitrate-free grown seedlings was about 3 to 4% of the control for NR345 and 14 to 16% of the control for NR328. Both mutants expressed inducible NR during early plant development and were sensitive to nitrate and urea inhibition of nodulation. These new mutants will allow an extension of the characterization of nitrate reductases and their function in soybean. Preliminary evidence indicates that NR345 is similar to the previously isolated mutant nr(1), while NR328 is different.
Poly(silicate)‐metabolizing silicatein in siliceous spicules and silicasomes of demosponges comprises dual enzymatic activities (silica polymerase and silica esterase) (2007)

Siliceous sponges can synthesize poly(silicate) for their spicules enzymatically using silicatein. We found that silicatein exists in silica-filled cell organelles (silicasomes) that transport the enzyme to the spicules. We show for the first time that recombinant silicatein acts as a silica polymerase and also as a silica esterase. The enzymatic polymerization/polycondensation of silicic acid follows a distinct course. In addition, we show that silicatein cleaves the ester-like bond in bis(p-aminophenoxy)-dimethylsilane. Enzymatic parameters for silica esterase activity are given. The reaction is completely blocked by sodium hexafluorosilicate and E-64. We consider that the dual function of silicatein (silica polymerase and silica esterase) will be useful for the rational synthesis of structured new silica biomaterials.
Effect of TiO2 Inclusion in the Poly(vinylidene fluoride-co-hexafluoropropylene)-Based Polymer Electrolyte of Dye-Sensitized Solar Cell (2006)

The approach of using polymer electrolytes haswer lo n i d e t l u res y ll ua us but st re e t n gh i hi h wit d e ct tra t a n e e bconversion efficiency than conventional Gratzel cell withliquid electrolyte. Among many polymer electrolytes, thepoly(vinylidene fluoride-co -hexafluoropropylene) (PVdF-Cs been haS DSn knowi n al x mi teri a r mt mar polyeas ) PHF
On the Unprecedented Scalability of the FISSION (Flexible Interconnection of Scalable Systems Integrated Using Optical Networks) Datacenter (2016)

Internet traffic is doubling almost every other year which implies that datacenter (DC) scalability will play a critical role in enabling future communications. In this paper, we propose FISSION (Flexible Interconnection of Scalable Systems Integrated using Optical Networks)-a scalable, fault-tolerant DC architecture based on a switchless optical-bus backplane and carrier-class switches, and its supporting protocol. The FISSION DC enables unprecedented scalability using affordable optics and standardized electrical switches. It is architecturally bifurcated into sectors that internally have a nonblocking carrier-class switching interconnection structure. Sectors are connected in the switchless backplane using optical buses. Each sector can receive traffic on all wavelengths (achieved through optical-bus property without any switch reconfiguration) and across all fibers, but a sector transmits on only a group of wavelengths and only in one of the fiber rings in the backplane. The switches function based on an SDN methodology that facilitate mapping of complex protocols and addresses to DC-specific addressing that is scalable and easier to use. We present an analysis to optimize the FISSION architecture. A simulation model is proposed that (1) compares the FISSION approach to other contemporary designs; (2) provides scalability analysis and protocol performance measurement; and, (3) provides optical layer modeling to validate working of the FISSION framework at high line-rates. Our architecture, which provides 100% bisection bandwidth, is validated by simulation results exhibiting negligible packet loss and low end-to-end latency.
Parametric waveform synthesis: a scalable approach to generate sub-cycle optical transients (2023)

The availability of electromagnetic pulses with controllable field waveform and extremely short duration, even below a single optical cycle, is imperative to fully harness strong-field processes and to gain insight into ultrafast light-driven mechanisms occurring in the attosecond time-domain. The recently demonstrated parametric waveform synthesis (PWS) introduces an energy-, power- and spectrum-scalable method to generate non-sinusoidal sub-cycle optical waveforms by coherently combining different phase-stable pulses attained via optical parametric amplifiers. Significant technological developments have been made to overcome the stability issues related to PWS and to obtain an effective and reliable waveform control system. Here we present the main ingredients enabling PWS technology. The design choices concerning the optical, mechanical and electronic setups are justified by analytical/numerical modeling and benchmarked by experimental observations. In its present incarnation, PWS technology enables the generation of field-controllable mJ-level few-femtosecond pulses spanning the visible to infrared range.
Carbon black reactor analysis (2005)

Isothermal gas simulation was performed for three patterns of carbon black (CB) reactors using standard k-ε model to treat turbulent flow. In addition, Lagrangean simulation was made to predict flow time corresponding to the time span of CB traveling in the hot gasses. Numerical results thus obtained are compared with geometrical properties of CB aggregate sampled from the CB reactors whose geometric shapes are the same as the numerical models. Numerical data suggested that flow time is key to control indicators of CB aggregate size.
CT-SRCNN: Cascade Trained and Trimmed Deep Convolutional Neural Networks for Image Super Resolution (2018)

We propose methodologies to train highly accurate and efficient deep convolutional neural networks (CNNs) for image super resolution (SR). A cascade training approach to deep learning is proposed to improve the accuracy of the neural networks while gradually increasing the number of network layers. Next, we explore how to improve the SR efficiency by making the network slimmer. Two methodologies, the one-shot trimming and the cascade trimming, are proposed. With the cascade trimming, the network's size is gradually reduced layer by layer, without significant loss on its discriminative ability. Experiments on benchmark image datasets show that our proposed SR network achieves the state-of-the-art super resolution accuracy, while being more than 4 times faster compared to existing deep super resolution networks.
A 5.5-GHz Background-Calibrated Subsampling Polar Transmitter With −41.3-dB EVM at 1024 QAM in 28-nm CMOS (2019)

We present a subsampling polar transmitter (SSPTX) in 28-nm CMOS that consists of a low-noise phase modulating (PM) digital subsampling phase-locked loop (PLL) and a harmonic rejection mixed (HRM) inverse-class-D (D <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-1</sup> ) digital power amplifier (DPA) for amplitude modulation (AM). The DPA is, unlike in a typical polar transmitter (TX), placed within the PLL and the phase-error detection happens directly at the DPA output. The subsampling polar TX thus becomes sensitive not only to phase errors but also to modulation amplitude. That feature enables AM-AM and PM-PM distortion to be detected and cancelled digitally in the background, while the transmitter operates normally. Moreover, the AM-PM cross distortion is filtered by the loop itself. The chip operates from a 0.9-V supply at 5.5 GHz with 2.5 MHz BW (1024 QAM) with average 1.1-dBm output power and total power consumption of 50 mW.
Reconstruction of pressure wavefields in the crossline direction using multicomponent streamer recordings (2008)

Three‐component measurements of particle motion would bring significant benefits to towed‐marine seismic data when processed in conjunction with the pressure data. We show that particle velocity measurements can increase the effective Nyquist wavenumber by a factor of two or three, depending on how they are used. A true, multicomponent streamer, therefore, would enable accurate data reconstruction in the crossline direction with cable separations for which pressure‐only data would be irrecoverably aliased. We also show that conventional workflows aimed at reducing these aliasing effects, such as moveout correction applied before interpolation, are compatible with multicomponent measurements. Some of the benefits of velocity measurements for deghosting data are well known. We outline how the new measurements may be used to address some long‐standing deghosting challenges of particular interest. Specifically, we propose methods for recovering deghosted data between streamers, and for the 3D deghosting of seismic data at the streamer locations.
Summarization of Business-Related Tweets: A Concept-Based Approach (2012)

We present a method for summarizing the collection of tweets related to a business. Our procedure aggregates tweets into subtopic clusters which are then ranked and summarized by a few representative tweets from each cluster. Central to our approach is the ability to group diverse tweets into clusters. The broad clustering is induced by first learning a small set of business-related concepts automatically from free text and then subdividing the tweets into these concepts. Cluster ranking is performed using an importance score which combines topic coherence and sentiment value of the tweets. We also discuss alternative methods to summarize these tweets and evaluate the approaches using a small user study. Results show that the concept-based summaries are ranked favourably by the users.
Fourier analysis computer-aided design of CCD signal processing analog multiplier arrays (1976)

The design of MOS multipliers with CAD was studied. In particular the Fourier analysis capability of the CAD program was used to analyze the harmonic distortion rejection, DR, of the multiplier.
Phosphorylation of E‐box binding USF‐1 by PI3K/AKT enhances its transcriptional activation of the WBP2 oncogene in breast cancer cells (2018)

WW domain binding protein 2 (WBP2), a transcriptional coactivator, plays a vital role in breast tumorigenesis. It positively regulates estrogen receptor, Hippo, and Wnt pathways, which subsequently enhance the transcription of downstream target genes contributing to cancer. Understanding the regulation of the expression and activity of WBP2 oncoprotein has implication in cancer therapy. We have previously reported that WBP2 is regulated at the post-translational and post-transcriptional levels. However, its regulation at the transcriptional level is not known. In this study, the minimal promoter region of WBP2 that is critical for its transcription was identified. The E-box motif in the WBP2 promoter was demonstrated to be essential for its transcription. The E-box binding protein upstream stimulatory factor 1 (USF-1) was discovered to be a key transcription factor for WBP2 by yeast one-hybrid analysis and was validated through reporter and chromatin immunoprecipitation assays and tandem mass spectrometry, which also suggested that USF-1 acts by regulating a network of genes, in addition to WBP2, associated with cell movement, proliferation, cell-cycle, and survival cellular processes. USF-1 is overexpressed in majority of the breast cancer cell lines and tissues tested, and has profound effects on cancer cell proliferation. USF-1-mediated transcription of WBP2 was demonstrated to be inducible by insulin, which led to AKT-mediated phosphorylation of USF-1 that modulated its ability to bind to the WBP2 promoter and activate its transcription. This study sheds new light onto the regulation of the WBP2 oncogene at the transcriptional level by a novel oncogenic transcription factor, USF-1. USF-1 is a potential drug target for treatment of WBP2-positive breast cancer.-Ramos, A., Miow, Q. H., Liang, X., Lin, Q. S., Putti, T. C., Lim, Y. P. Phosphorylation of E-box binding USF-1 by PI3K/AKT enhances its transcriptional activation of the WBP2 oncogene in breast cancer cells.
An Accurate Algorithm for Airborne SAR Processing with Variable Doppler Centroid. (1994)

This paper proposes a new approach for high resolution airborne SAR data processing, which uses a modified chirp scaling algorithm to accommodate the correction of motion errors, as well as the variations of the Doppler centroid in range and azimuth.
Extracellular ATP and CD39 Regulates Mitochondrial Function and Cytarabine Resistance through Intrinsic PKA-ATF-PGC1a Pathway in Acute Myeloid Leukemia (2018)

Abstract Relapses in acute myeloid leukemia (AML) are caused by chemoresistant leukemic populations and new therapeutic approaches that specifically target these cells are urgently needed. Based on transcriptomic analyses of relevant PDX preclinical model of the resistance to cytarabine (AraC) and of the residual disease in patients, we identified ecto-nucleoside triphosphate diphosphohydrolase-1 CD39 (ENTPD1) overexpressed in the residual leukemic cells in vivo after chemotherapy. By flow cytometry, we confirmed that AraC increased cell surface CD39 expression in AML cell lines in vitro and in vivo as well as in 24 diverse patient-derived xenograft models. We further observed this increase in 100 patients at 35-days post-intensive chemotherapy compared to their respective diagnosis. Interestingly, high CD39 expression on AML patients was associated with a worse response to AraC in vivo. Furthermore, we showed that FACS-sorted CD39high AML cells had increased mitochondrial mass and activity, and were resistant to AraC in vitro and in vivo. We demonstrated that CD39 downstream signaling pathway was dependent on cAMP-PKA-PGC1a-TFAM axis and its inhibition by H89 sensitized AML cells to AraC through the inhibition of mitochondrial OxPHOS biogenesis and function. Finally, pharmacological inhibition of CD39 ATP hydrolase activity or genetic invalidation of CD39 protein using two inhibitors or shRNA markedly enhanced AraC cytotoxicity in AML cell lines and primary patient samples in vitro and in vivo. Together, these results indicate CD39 as a new player of the intrinsic chemoresistance pathway and a new therapeutic target to specifically overcome AraC resistance and eradicate these leukemic cells responsible for relapses in AML. Disclosures No relevant conflicts of interest to declare.
Optimistic parallelism requires abstractions (2007)

Irregular applications, which manipulate large, pointer-based data structures like graphs, are difficult to parallelize manually. Automatic tools and techniques such as restructuring compilers and run-time speculative execution have failed to uncover much parallelism in these applications, in spite of a lot of effort by the research community. These difficulties have even led some researchers to wonder if there is any coarse-grain parallelism worth exploiting in irregular applications. In this paper, we describe two real-world irregular applications: a Delaunay mesh refinement application and a graphics application thatperforms agglomerative clustering. By studying the algorithms and data structures used in theseapplications, we show that there is substantial coarse-grain, data parallelism in these applications, but that this parallelism is very dependent on the input data and therefore cannot be uncoveredby compiler analysis. In principle, optimistic techniques such asthread-level speculation can be used to uncover this parallelism, but we argue that current implementations cannot accomplish thisbecause they do not use the proper abstractions for the data structuresin these programs. These insights have informed our design of the Galois system , an object-based optimistic parallelization system for irregular applications. There are three main aspects to Galois: (1) a small number of syntactic constructs for packaging optimistic parallelism as iteration over ordered and unordered sets, (2)assertions about methods in class libraries, and (3) a runtime scheme for detecting and recovering from potentially unsafe accesses to shared memory made by an optimistic computation. We show that Delaunay mesh generation and agglomerative clustering can be parallelized in a straight-forward way using the Galois approach, and we present experimental measurements to show that this approach is practical. These results suggest that Galois is a practical approach to exploiting data parallelismin irregular programs.
N-substituted derivatives of 23-amino-4',23-dideoxymycaminosyl tylonolide. Synthesis and antibacterial activity. (1985)

23-Amino-4',23-dideoxymycaminosyl tylonolide diethyl acetal (5) has been prepared from 4',23-dideoxy-23-iodomycaminosyl tylonolide diethyl acetal (3) by treatment with sodium azide followed by selective reduction of the resulting azide (4). 23-Acylamino-23-deoxy (6 approximately 8) and 23-deoxy-23-urethane-type compounds (12 approximately 15) were further prepared. Treatment of the 23-alkylamino-4',23-dideoxymycaminosyl tylonolides (9, 10) with chloroformates gave 23-N-alkyl-23-deoxy-23-urethane-type compounds (16 approximately 21, 29, 30). 23-N-Alkyl-23-deoxy-23-(2-hydroxyethalamino and 2-methoxyethylamino)-4',23-dideoxymycaminosyl tylonolides (22 approximately 25, 27, 28) were prepared from 3 and the corresponding amines. Antibacterial activities and toxicities (for 23 and 27) of these compounds are described. toxicities (for 23 and 27) of these compounds are described.
Exploiting integrated GPUs for network packet processing workloads (2016)

Software-based network packet processing on standard high volume servers promises better flexibility, manageability and scalability, thus gaining tremendous momentum in recent years. Numerous research efforts have focused on boosting packet processing performance by offloading to discrete Graphics Processing Units (GPUs). While integrated GPUs, residing on the same die with the CPU, offer many advanced features such as on-chip interconnect CPU-GPU communication, and shared physical/virtual memory, their applicability for packet processing workloads has not been fully understood and exploited. In this paper, we conduct in-depth profiling and analysis to understand the integrated GPU's capabilities and performance potential for packet processing workloads. Based on that understanding, we introduce a GPU accelerated network packet processing framework that fully utilizes integrated GPU's massive parallel processing capability without the need for large numbers of packet batching, which might cause a significant processing delay. We implemented the proposed framework and evaluated the performance with several common, light-weight packet processing workloads on the Intel <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">®</sup> Xeon <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">®</sup> Processor E3-1200 v4 product family (codename Broadwell) with an integrated GT3e GPU. The results show that our GPU accelerated packet processing framework improved the throughput performance by 2-2.5x, compared to optimized packet processing on CPU only.