gebhart/patrepeval huggingface dataset:
Battery emulation considering thermal behavior (2011)

Electric propulsion becomes more and more important. Despite the fact that appropriate design tools tailored for the use with electric propulsion systems have to be developed, test benches for verification and hardware-in-the-loop simulations are needed. The battery system, as it is a very important component, is in the focus of this article. Facing the costs of real hardware components a realtime emulation with programmable power supplies and electric loads seems reasonable. This article introduces an approaches in battery modeling and figures out the main influences of the model parameters. Because of a very strong impact of the thermal behavior on the parameters a dedicated thermal model is proposed. One major point is the modularized modeling and the coupling of the different physical domains. The advantage of this approach is that the granularity of the single modules can be adjusted separately to fit the dedicated needs of a given task. For battery emulation the entire model has to be implemented on a realtime platform. The article gives a detailed overview and demonstrates the feasibility of the entire system in practical experiments.
Characterization of the RNA-fork model of virion RNA in the initiation of transcription in influenza A virus (1995)

It has been shown that both 3' and 5' conserved termini of influenza A virus virion RNA are involved in the initiation of transcription. An RNA-fork model has been proposed, according to which there is a crucial double-stranded region formed by complementary bases at positions 10 to 12 of the 3' terminus and bases at positions 11' to 13' of the 5' terminus, which are extended by 2 or 3 segment-specific base pairs. The two termini at positions 1 to 9 and 1' to 10' in the 3' and 5' termini, respectively, are in a single-stranded conformation. Here we further characterize this model, focusing on the individual roles of the proposed duplex region and the proposed two single-stranded ends. Residues within the conserved 5' terminus that are involved in the initiation of transcription were determined. Single, double, and triple mutations in the proposed duplex region provided further evidence that, for the initiation of transcription in vitro, the duplex RNA is more important than the actual sequence of these residues, although some restrictions in sequence were apparent. On the other hand, there was evidence that base pairing is not required at residues 1 to 7. We propose that the 5' terminus of virion RNA should be treated as an integral part of the virion RNA promoter and discuss a possible mechanism for the recognition of the virion RNA promoter by the influenza A virus RNA polymerase complex.
Energy Efficient MAC protocols for Mobile Sensor Networks (2010)

A Mobile Sensor Network is a geographically distributed network which owes its name to the presence of mobile sink or sensor nodes within the network.In this paper we will present and discuss the energy-efficient contention-based and scheduled based medium access control (MAC) protocols for mobile sensor networks (MSNs).Most of the MAC protocols such as T-MAC , D-MAC, and the more commonly utilized SMAC proposed for wireless sensor networks assume sensors to be stationary after deployment, which usually provide very bad network performance in scenarios involving mobile sensors.Handling mobility in wireless sensor networks in an energy-efficient way is a new challenge.We present new MAC layer approaches to support mobility in WSNs such as MS-MAC extends S-MAC to include mobility-awareness by decreasing this sleep duration when mobility is detected.S-MAC with Extended Kalman filter (EKF) reduces mobility-incurred losses by predicting the optimal data frame size for each transmission.M-LMAC (Mobile LMAC) as a TDMA-based MAC protocol which can support continuous mobility in the wireless sensor networks.MMAC utilizes a dynamic mobility-adaptive frame time to enhance TRAMA, a scheduled-based protocol, with mobility prediction.Likewise, G-MAC utilizes TDMA for cluster-based WSNs by combining the advantages of contention and contention-free MACs.All of the above MAC protocols are reviewed in detail.
The effects of customised brainwave music on orofacial pain induced by orthodontic tooth movement (2016)

Brainwave music is effective in controlling orthodontic pain, possibly via restoring functional connectivity and brain regularity influenced by pain.
Ion Mobility Spectrometry of Drugs of Abuse in Customs Scenarios: Concentration and Temperature Study (1992)

A custom-built ion mobility spectrometer has been used to obtain the IMS spectra of cocaine, heroin, amphetamine sulfate and LSD at different drug concentrations and desorption temperatures. Practical detection limits for these four drugs were obtained as a function of desorber temperature and for heroin as a function of analysis time. Spectral and ionization interferences for each of the four drugs of interest were determined. Spectral interferences by innocuous materials are few; ionization interferences occur only at very high ratios of the mass of innocuous material to that of the drug of interest.
INTERNET ADDICTION AMONG UNDERGRADUATES IN UNIVERSITY OF IBADAN: IMPERATIVE FOR COUNSELLING INTERVENTION (2015)

The extent to which psychological and contextual factors (locus of control, self-concept and parenting styles) correlate with internet addiction among undergraduates in University of Ibadan was examined in this study. Survey design of correlational type was adopted to execute the study. Simple random sampling technique was utilized to draw four hundred and forty-two (Male: 247=female=195) undergraduates with age range of 16 to 26 year (=1.44; SD=.49) from University of Ibadan. The Data source was four  self-report questionnaire namely; Young (1996) internet Addition Test; Darling and Toyokawa (1997) Parenting Style Inventory; Levenson (1974) Locus of Control scale and Robinson (1989) self concept questionnaire. Pearson’s Product Moment Correlation and multiple regression were used to analyze data at 0.05 level of significance. Result show that the hypothesized variables have significant correlation with internet addition. The composite contribution of the independent variables to the prediction of internet addition was significant. It jointly contributed for about 20% of the variance in the prediction of internet addition of the respondents. Locus of control was the most potent ( =0.128; t =2.554; P<0.05) while self concept had the least contribution to the prediction of internet addition. The outcome has implications for parents, psychologists, educators and policy makers.
Acute Kawasaki disease is associated with reverse regulation of soluble receptor for advance glycation end products and its proinflammatory ligand S100A12 (2007)

Inverse regulation of both sRAGE and its proinflammatory ligand S100A12 seems to be a relevant molecular mechanism promoting systemic inflammation. Calculating the S100A12:sRAGE ratio might help to detect patients with KD who are at risk of being unresponsive to IVIG therapy.
The Benefits of Controlled Experimentation at Scale (2017)

Online controlled experiments (for example A/B tests) are increasingly being performed to guide product development and accelerate innovation in online software product companies. The benefits of controlled experiments have been shown in many cases with incremental product improvement as the objective. In this paper, we demonstrate that the value of controlled experimentation at scale extends beyond this recognized scenario. Based on an exhaustive and collaborative case study in a large software-intensive company with highly developed experimentation culture, we inductively derive the benefits of controlled experimentation. The contribution of our paper is twofold. First, we present a comprehensive list of benefits and illustrate our findings with five case examples of controlled experiments conducted at Microsoft. Second, we provide guidance on how to achieve each of the benefits. With our work, we aim to provide practitioners in the online domain with knowledge on how to use controlled experimentation to maximize the benefits on the portfolio, product and team level.
Functional expression of smooth muscle-specific ion channels in TGF-β<sub>1</sub>-treated human adipose-derived mesenchymal stem cells (2013)

Human adipose tissue-derived mesenchymal stem cells (hASCs) have the power to differentiate into various cell types including chondrocytes, osteocytes, adipocytes, neurons, cardiomyocytes, and smooth muscle cells. We characterized the functional expression of ion channels after transforming growth factor-β1 (TGF-β1)-induced differentiation of hASCs, providing insights into the differentiation of vascular smooth muscle cells. The treatment of hASCs with TGF-β1 dramatically increased the contraction of a collagen-gel lattice and the expression levels of specific genes for smooth muscle including α-smooth muscle actin, calponin, smooth mucle-myosin heavy chain, smoothelin-B, myocardin, and h-caldesmon. We observed Ca(2+), big-conductance Ca(2+)-activated K(+) (BKCa), and voltage-dependent K(+) (Kv) currents in TGF-β1-induced, differentiated hASCs and not in undifferentiated hASCs. The currents share the characteristics of vascular smooth muscle cells (SMCs). RT-PCR and Western blotting revealed that the L-type (Cav1.2) and T-type (Cav3.1, 3.2, and 3.3), known to be expressed in vascular SMCs, dramatically increased along with the Cavβ1 and Cavβ3 subtypes in TGF-β1-induced, differentiated hASCs. Although the expression-level changes of the β-subtype BKCa channels varied, the major α-subtype BKCa channel (KCa1.1) clearly increased in the TGF-β1-induced, differentiated hASCs. Most of the Kv subtypes, also known to be expressed in vascular SMCs, dramatically increased in the TGF-β1-induced, differentiated hASCs. Our results suggest that TGF-β1 induces the increased expression of vascular SMC-like ion channels and the differentiation of hASCs into contractile vascular SMCs.
<i>De Novo</i> Design of Native Proteins:  Characterization of Proteins Intended To Fold into Antiparallel, Rop-like, Four-Helix Bundles (1997)

The de novo design and characterization of a series of 51-residue helix-turn-helix peptides intended to dimerize into antiparallel four-stranded coiled coils is described. The sequence is based on a coiled coil heptad repeat Ncap-(Aa Zb Zc Ld Ze Zf Zg)3-turn- (Xa Zb Zc Ld Ze Zf Zg)3-Ccap-CONH2, where X is either Val or Ala. The overall topology was intended to be similar to that found in the Escherichia coli protein ROP. The design strategy included consideration of geometric complementarity of the packing of side chains within the hydrophobic core as well as the use of specific interfacial interactions, both of which were intended to favor the desired ROP-like topology. Additionally, the sequence was designed to destabilize potential alternative structures that might compete with the desired topology. The peptides (RLP-1, RLP-2, and RLP-3) assemble into stable alpha-helical dimers and exhibit the hallmarks of a native protein as judged by its spectroscopic properties, and the lack of binding to hydrophobic dyes. Also, the enthalpy and heat capacity changes upon denaturation were determined by measuring the temperature dependence of the CD spectra and confirmed by differential scanning calorimetry (DSC). The values determined by the two methods are in excellent agreement and are in the range of those of naturally occurring proteins of this size. These results suggest that it is now possible to design native-like helical proteins that should serve as templates for the further design of functional proteins.
Neuroprotective effect of L‐serine against temporary cerebral ischemia in rats (2010)

To investigate the neuroprotective effect of L-serine and its underlying mechanisms, focal cerebral ischemia was induced in rats by occlusion of middle cerebral artery (MCAO) with a suture, and reperfusion was given by filament withdrawal 2 hr later. Meanwhile, rat hippocampal neurons were primarily cultured, and incubated in serum-free medium in an incubator containing 1% O(2) for hypoxic exposure of 5 hr, or incubated in serum-free medium containing 1 mM glutamate for glutamate exposure of 2 hr. Brain tissue injury and cell damage were then measured. L-serine dose-dependently decreased the neurology deficit score and infarct volume, elevated the cell viability and inhibited the leakage of lactate dehydrogenase. These effects were blocked by strychnine in both MCAO rats and cultured hippocampal neurons. Furthermore, L-serine (168 mg.kg(-1)) reduced the brain water content, permeability of blood-brain barrier, neuronal loss and the expression of activated caspase-3 in the cortex. In addition, L-serine effectively protected the brain from damage when it was administered within 6 hr after the end of MCAO. It is suggested that L-serine could exert a neuroprotective effect on the ischemic-reperfused brain and on the hypoxia- or glutamate-exposed hippocampal neurons, which may be mediated by activating glycine receptors.
Platinum group metal-free NiMo hydrogen oxidation catalysts: high performance and durability in alkaline exchange membrane fuel cells (2017)

A highly active NiMo electrocatalyst for HOR in alkaline media with power density at 0.5 V higher than 100 mW cm<sup>−2</sup> (peak value of 120 mW cm<sup>−2</sup>), which is similar to palladium was synthesized and comprehensively studied.
High speed silicon microring modulator employing dynamic intracavity energy balance (2012)

High speed coupling-modulation of a microring-based light drop structure is proposed, which removes severe signal distortion due to intracavity energy depletion and separates the modulation speed from the resonator linewidth restriction. Extinction ratio improvement from <1 dB to >20 dB with 40 Gb/s non-return-to-zero (NRZ) signals is obtained with 25 times smaller drive voltage. The tolerance to active ring propagation loss is increased from 5 dB/cm to over 25 dB/cm with less than 5% modulation bandwidth reduction. The possibility of obtaining 160 Gb/s NRZ signal with no more than 4 V drive voltage and less than 5 dB insertion loss is highlighted.
Requirements for High Flux Cooling of Future Avionics Systems (1991)

<div class="htmlview paragraph">An industry survey was performed to determine future needs for high flux heat removal in advanced electronics systems. The focus of the survey was to determine technology development requirements for military avionics systems. Commercial electronics suppliers were included because many high-power devices are being developed in that part of the industry. This paper presents a summary of all of the interviews and literature reviewed. The summary is sorted by broad application categories, which are: 1) commercial digital systems, 2) military data processors, 3) power processors, and 4) radar and optical systems. For applications expected to be fielded in five to ten years, the outlook is for steady state flux levels of 100 watts per chip for digital processors and several hundred watts per device for power control applications using advanced MOSFETs or MOS-controlled thyristor technology.</div>
A Generative 3D Facial Model by Adversarial Training. (2019)

Data-driven generative 3D face models are used to compactly encode facial shape data into meaningful parametric representations. A desirable property of these models is their ability to effectively decouple natural sources of variation, in particular identity and expression. While factorized representations have been proposed for that purpose, they are still limited in the variability they can capture and may present modeling artifacts when applied to tasks such as expression transfer. In this work, we explore a new direction with Generative Adversarial Networks and show that they contribute to better face modeling performances, especially in decoupling natural factors, while also achieving more diverse samples. To train the model we introduce a novel architecture that combines a 3D generator with a 2D discriminator that leverages conventional CNNs, where the two components are bridged by a geometry mapping layer. We further present a training scheme, based on auxiliary classifiers, to explicitly disentangle identity and expression attributes. Through quantitative and qualitative results on standard face datasets, we illustrate the benefits of our model and demonstrate that it outperforms competing state of the art methods in terms of decoupling and diversity.
Profilaxia do tromboembolismo venoso no doente cirúrgico (2014)

O papel da anestesiologia numa responsabilidade multidisciplinar A eficácia da profilaxia do tromboembolismo venoso no doente cirúrgico está demonstrada e tem um grande impacto epidemiológico e económico. Os recursos e indicações em termos de terapêutica profilática devem ter em conta os fatores de risco específicos do doente, aqueles inerentes ao procedimento cirúrgico e os relacionados com a própria anestesia. Apesar do evidente contributo para a melhoria do prognóstico, as recomendações de profilaxia do tromboembolismo venoso no doente cirúrgico continuam a não estar completamente implementadas nos hospitais. Este facto prende-se com várias barreiras, desde o desconhecimento das recomendações, à dificuldade em avaliar diferentes graus de risco e populações de risco adicional, ao receio de complicações associadas, até à ainda não integrada responsabilidade multidisciplinar. Acresce a necessidade de reforçar a importância do registo de execução e do controle de processo. Os reguladores já puseram em prática programas no sentido de vencer estas barreiras, mas estamos longe de um nível de excelência transversal a todo o doente cirúrgico. O objectivo deste artigo é apresentar as mais recentes recomendações de prevenção do tromboembolismo venoso no doente cirúrgico, nomeadamente as do nono consenso do American College of Chest Physicians e as suas implicações na conduta anestésica, procurando estratégias para vencer algumas das barreiras existentes à sua implementação.
Justice et médias : faut-il une caméra dans la salle d'audience ? (2006)

International audience
Polymeric phosphonium salts as a novel class of cationic biocides. X. Antibacterial activity of filters incorporating phosphonium biocides (1994)

Abstract Phosphonium salts with different alkyl chains as substituents were incorporated covalently on the surfaces of cellulose filters with silane coupling agents containing phosphonium ions, and their surface antibacterial activities against Staphylococcus aureus and Escherichia coli were explored by the viable cell‐counting method in sterile distilled water. The filters incorporating phosphonium biocides showed higher antibacterial activity, and its activity strongly depended on the structure of substituents. The surface‐treated filters may be used to sterilize air and water, including microorganisms. © 1994 John Wiley & Sons, Inc.
New vacuum pumping system for 4000-ton di-methyl phosphite (2002)

In di methyl phosphite vacuum pumping system the gas circulation cooled roots vacuum pump system can replace multi reciprocating vacuum pump combination in parallel which is commonly used in the past. Applications of the gas circulation cooled roots vacuum pump system can lower power consumption, raise pumping efficiency and reduce maintenance expenses greatly.
Potential Antitumor Agents, VIII<sup>1)</sup> Allyl, Propargyl and Cyanomethyl Esters of Imidazo[2,1‐<i>b</i>]thiazole‐5‐carboxylic Acids (1983)

Abstract The imidazo[2,1‐ b ]thiazole‐5‐carboxylic acids 1 and 2 were used as starting materials for the synthesis of allyl 3a—c, 6a—c , propargyl 4a—c, 7a—c and cyanomethyl esters 5a—c, 8a—c. Under the conditions employed these compounds did not show significant antitumor activity.
SPICE Modeling for Small Geometry MOSFET Circuits (1982)

VLSI circuit simulation requires computationally efficient MOSFET models. In this paper, VLSI circuit simulator models for the active device and some important passive devices are described. A quasi-physical short channel MOSFET current model is derived. This current model contains both above-threshold and subthreshold components. The values of the model parameter are extracted automatically from measured I-V data. The reduction in process information in this representation is shown to be tolerable using a proper quantization of the geometry and device type space. Narrow width effect is also included. A charge conserving MOSFET capacitor model is also given. The importance of the parasitic devices on VLSI circuit is shown and a model for the fringing capacitance due to finite gate thickness is introduced. A "process box" based on the statistical variation of parameters is extracted from a completely automated device characterization system. Experimental results indicate that the width and length are independent random variables. This statistical information allows the circuit response to be simulated across the process window.
Penetrance of von Recklinghausen neurofibromatosis: a distinction between predecessors and descendants. (1988)

This paper reviews the concepts of penetrance and expressivity and examines their application to the specific disorder von Recklinghausen neurofibromatosis. The data suggest that assessments of penetrance among predecessors to probands yield results different from those of assessments of penetrance among descendants to probands. For descendants at risk, penetrance is very close to 100%. For predecessors at risk, extremely variable expressivity may confound estimates of penetrance; as a specific example, a family is described in which two brothers have bona fide von Recklinghausen neurofibromatosis and their mother manifests the neurofibromatosis mutation only as iris Lisch nodules.
Stabilization ofD-amino acid oxidase and catalase in permeabilizedRhodotorula graciliscells and its application for the preparation of α-ketoacids* (2000)

The cellular D-amino acid oxidase (DAAO) and catalase activities of Rhodotorula gracilis were greatly increased upon the treatment of the cells with cetyltrimethylammonium bromide (CTAB). However, these enzymes, slowly leaks out from the permeabilized cells. The released DAAO was rapidly inactivated in the absence of ethylenediaminotetraacetic acid (EDTA), beta-mercaptoethanol, and glycerol. DAAO within the permeabilized cells did not require these stabilizing agents. Treating the CTAB-permeabilized cells with 0.2% glutaraldehyde (GA) at 4 degrees C for 10 min prevented the leakage of both DAAO and catalase. Alternately, stabilized whole cell DAAO and catalase was prepared by treating the whole yeast cells with 1% GA at 4 degrees C for 60 min, followed by permeabilization with CTAB, a method which was equally efficient but easy to scale up. CTAB-permeabilized cells converted D-phenylalanine to 97% phenylpyruvate and 3% phenylacetate, and these cells were reused up to 3 cycles in a batchwise reaction. On the other hand, GA-treated CTAB-permeabilized cells produced more than 99% phenylpyruvate and the cells could be reused up to 20 cycles.