gebhart/patrepeval huggingface dataset:
Efficient Online Surface Correction for Real-time Large-Scale 3D Reconstruction (2017)

State-of-the-art methods for large-scale 3D reconstruction from RGB-D sensors usually reduce drift in camera tracking by globally optimizing the estimated camera poses in real-time without simultaneously updating the reconstructed surface on pose changes. We propose an efficient on-the-fly surface correction method for globally consistent dense 3D reconstruction of large-scale scenes. Our approach uses a dense Visual RGB-D SLAM system that estimates the camera motion in real-time on a CPU and refines it in a global pose graph optimization. Consecutive RGB-D frames are locally fused into keyframes, which are incorporated into a sparse voxel hashed Signed Distance Field (SDF) on the GPU. On pose graph updates, the SDF volume is corrected on-the-fly using a novel keyframe re-integration strategy with reduced GPU-host streaming. We demonstrate in an extensive quantitative evaluation that our method is up to 93% more runtime efficient compared to the state-of-the-art and requires significantly less memory, with only negligible loss of surface quality. Overall, our system requires only a single GPU and allows for real-time surface correction of large environments.
15세기 한(韓),중(中) 『내훈(內訓)』의 여성윤리 (2011)

『內訓』은 1475년 仁粹大妃 韓氏가 편찬한 여훈서이다. 인수대비는 여러 시기의 다양한 형태, 다양한 내용의 글 가운데서 여성윤리와 관련이 있는 것들을 모아 이 책을 편찬하였다. 이 보다 70여 년 전에 명나라의 文皇后 徐氏 역시 같은 제목의 책을 저술하였다. 따라서 이 두 책을 구분하기 위해 前者는 『大妃內訓』, 後者는 『皇后內訓』이라고 하였다. 이 두 책은 그 편찬체제나 서술 방식이 전혀 다르며, 또 인수대비는 문황후의 책에 대해 알지 못하였다. 그럼에도 불구하고 이 두 책에 담겨있는 여성윤리의 기본 내용은 정확하게 일치하였다. 이 두 『내훈』이 보급되기 이전의 대표적인 여훈서는 『女誡』였다. 『여계』에 담겨있는 여성윤리는 陰陽尊卑論과 敬順論으로 특징지을 수 있다. 敬順은 남편의 권위에 복종하는 마음가짐과 행동을 포괄적으로 표현하는 개념이다. 음양존비론은 여성이 이 경순이라는 도덕규범을 실천해야 하는 당위성을 설명하는 논리이다. 남녀를 자연의 양과 음에 배당하고, 그 양과 음의 본성을 강유, 존비로 설명함으로써 아내의 남편에 대한 복종을 정당화한다. 두 『내훈』 모두 이 음양존비론과 경순론을 그대로 받아들인다. 그러나 두 『내훈』은 모두 『여계』의 여성윤리에 만족하지는 않았다. 이미 『소학』을 통해 새로운 여성윤리, 즉 德性論이라는 윤리사상과 節義論이라는 도덕규범을 포함하는 여성윤리가 제시되었고, 인수대비와 문황후는 이 새로운 여성윤리를 보급할 여훈서를 편찬하고자 하였다. 여성윤리로서의 절의론은 아내가 남편에게 지켜야 할 의리가 守節과 內助라고 가르친다. 그리고 여성이 이러한 의리를 실천해야 하는 당위성을 여성이 갖추고 있는 도덕적 본성, 즉 德性에서 찾는다. 두 『내훈』 모두 여성의 도덕적 실천은 여성 자신에 내재하는 도덕적 본성의 실현으로 파악한다. 따라서 그 내용에서 言行을 비롯한 여성의 修身에 관한 부분이 중요한 비중을 차지한다. 또 절의를 여성들이 실천해야 하는 도덕규범으로 제시하면서, 그 절의의 내용 가운데서 수절에 관한 내용에는 관심이 없고 내조에 관한 내용에만 관심을 보인다는 점에서도 두 『내훈』은 공통적이다. 이러한 특징은 『내훈』을 편찬한 두 사람이 염두에 두었던 가장 중요한 보급대상이 왕실의 여성이었기 때문으로 보인다.
Shear‐induced platelet‐derived growth factor gene expression in human endothelial cells is mediated by protein kinase C (1992)

Our previous studies have shown that steady shear stress causes a transient increase of platelet-derived growth factor (PDGF) A and B chain mRNA levels in human umbilical vein endothelial cells (HUVEC). In the present study, we elucidated the signaling pathway of shear stress in HUVEC by examining the roles of protein kineses, intracellular calcium, cyclooxygenase, and guanine nucleotide-binding proteins (G proteins) in the PDGF gene induction by shear. The protein kinase C inhibitors, H7 and staurosporine, strongly inhibited the shear-induced PDGF gene expression in HUVEC. In contrast, HA1004, a cAMP- and cGMP-dependent protein kinases inhibitor, was only slightly inhibitory. BAPTA/AM, an intracellular calcium chelator, partially (50%) inhibited the shear-induced PDGF gene expression. The cyclooxygenase inhibitors, ibuprofen and indomethacin, were slightly inhibitory. A 35-50% inhibition of shear-induced PDGF gene expression was found with GDP-beta-S, an inhibitor of G proteins. These results suggest that shear-induced PDGF gene expression in HUVEC is mainly mediated by protein kinase C activation and requires intracellular calcium. Furthermore, G proteins seem to be involved in this process, whereas prostaglandin synthesis via cyclooxygenase pathway is not. We propose a mechanism of shear-induced PDGF gene expression in HUVEC: Shear stress, either directly or indirectly (G protein-mediated), enhances the membrane phosphoinositide turnover via phospholipase C, producing diacylglycerol, an activator of protein kinase C. The activated protein kinase C then triggers the subsequent PDGF gene expression.
Unique Drought Resistance Functions of the<i>Highly ABA-Induced</i>Clade A Protein Phosphatase 2Cs     (2012)

Six Arabidopsis (Arabidopsis thaliana) clade A protein phosphatase 2Cs (PP2Cs) have established abscisic acid (ABA) signaling roles; however, phenotypic roles of the remaining three "HAI" PP2Cs, Highly ABA-Induced1 (HAI1), AKT1-Interacting PP2C1/HAI2, and HAI3, have remained unclear. HAI PP2C mutants had enhanced proline and osmoregulatory solute accumulation at low water potential, while mutants of other clade A PP2Cs had no or lesser effect on these drought resistance traits. hai1-2 also had increased expression of abiotic stress-associated genes, including dehydrins and late embryogenesis abundant proteins, but decreased expression of several defense-related genes. Conversely, the HAI PP2Cs had relatively less impact on several ABA sensitivity phenotypes. HAI PP2C single mutants were unaffected in ABA sensitivity, while double and triple mutants were moderately hypersensitive in postgermination ABA response but ABA insensitive in germination. The HAI PP2Cs interacted most strongly with PYL5 and PYL7 to -10 of the PYL/RCAR ABA receptor family, with PYL7 to -10 interactions being relatively little affected by ABA in yeast two-hybrid assays. HAI1 had especially limited PYL interaction. Reduced expression of the main HAI1-interacting PYLs at low water potential when HAI1 expression was strongly induced also suggests limited PYL regulation and a role of HAI1 activity in negatively regulating specific drought resistance phenotypes. Overall, the HAI PP2Cs had greatest effect on ABA-independent low water potential phenotypes and lesser effect on classical ABA sensitivity phenotypes. Both this and their distinct PYL interaction demonstrate a new level of functional differentiation among the clade A PP2Cs and a point of cross talk between ABA-dependent and ABA-independent drought-associated signaling.
Chemical Synthesis of <i>Escherichia Coli</i> ST<sub>h</sub> Analogues by Regioselective Disulfide Bond Formation:  Biological Evaluation of an <sup>111</sup>In-DOTA−Phe<sup>19</sup>-ST<sub>h</sub> Analogue for Specific Targeting of Human Colon Cancers (2002)

New human Escherichia coli heat-stable peptide (ST(h)) analogues containing a DOTA chelating group were synthesized by sequential and selective formation of disulfides bonds in the peptide. This synthetic approach utilizes three orthogonal thiol-protecting groups, Trt, Acm, and t-Bu, to form three disulfide bonds by successive reactions using 2-PDS, iodine, and silyl chloride-sulfoxide systems. The DOTA-ST(h) conjugates exhibiting high guanylin/guanylate cyclase-C (GC-C) receptor binding affinities were obtained with >98% purity. In vitro competitive binding assays, employing T-84 human colon cancer cells, demonstrated the IC(50) values of <2 nM for GC-C receptor binding suggesting that the new synthetic ST(h) analogues are biologically active. In vitro stability studies of the (111)In-DOTA-Phe(19)-ST(h) conjugate incubated in human serum at 37 degrees C under 5% CO(2) atmosphere revealed that this conjugate is extremely stable with no observable decomposition at 24 h postincubation. HPLC analysis of mouse urine at 1 h pi of the (111)In-DOTA-Phe(19)-ST(h) conjugate showed only about 15% decomposition suggesting that the (111)In-DOTA-Phe(19)-ST(h) conjugate is highly stable, even under in vivo conditions. In vivo pharmacokinetic studies of the (111)In-DOTA-Phe(19)-ST(h) conjugate in T-84 human colon cancer derived xenografts in SCID mice conducted at 1 h pi showed an initial tumor uptake of 2.04 +/- 0.30% ID/g at 1 h pi with efficient clearance from the blood pool (0.23 +/- 0.14% ID/g, 1 h pi) by excretion mainly through the renal/urinary pathway (95.8 +/- 0.2% ID, 1 h pi). High tumor/blood, tumor/muscle, and tumor/liver ratios of approximately 9:1, 68:1, and 26:1, respectively, were achieved at 1 h pi The specific in vitro and in vivo uptake of the radioactivity by human colonic cancer cells highlights the potential of radiometalated-DOTA-ST(h) conjugates as diagnostic/therapeutic radiopharmaceuticals.
Selective deep brain stimulation in the substantia nigra reduces myoclonus in progressive myoclonic epilepsy: a novel observation and short review of the literature (2019)

We report the case of a patient suffering from pharmacotherapy-resistant bilateral progressive myoclonic epilepsy (PME) showing a beneficial response upon selective deep brain stimulation (DBS) of the substantia nigra pars reticulata. As an individual experimental therapeutic approach, we implanted DBS electrodes in the transitional zone between the subthalamic nucleus (STN) and the substantia nigra pars reticulata (SNr). Electrode placement allowed for a selective stimulation of either the STN, SNr, or both targets. Postoperatively, we observed a moderate subjective and objective improvement in positive and negative myoclonus by high-frequency DBS of the STN/SNr transitional zone. However, a systematic exploration of different stimulation settings revealed that monopolar stimulation of the substantia nigra alone was more effective than high-frequency monopolar DBS of either the motor STN (monopolar) or stimulation of both targets (STN/SNr). This observation confirms earlier findings showing that patients with PME benefit from high-frequency DBS. However, in contrast to previous reports stimulating the STN/SNr transitional zone, our patient showed the most significant effect upon selective stimulation of the SNr. We propose that in patients undergoing DBS for myoclonus, at least one electrode contact should be placed in the SNr allowing for selective monopolar stimulation of this target.
OAuth Token Introspection (2014)

This specification defines a method for a client or protected resource
to query an OAuth authorization server to determine meta- information
about an OAuth token.
Chemical Vapor Deposition of Ga<sub>2</sub>O<sub>3</sub>Thin Films on Si Substrates (2002)

Amorphous <TEX>$Ga_2O_3$</TEX> films have been grown on Si(100) substrates by metal organic chemical vapor deposition (MOCVD) using gallium isopropoxide, <TEX>$Ga(O^iPr)_3$</TEX>, as single precursor. Deposition was carried out in the substrate temperature range 400-800 <TEX>$^{\circ}C$</TEX>. X-ray photoelectron spectroscopy (XPS) analysis revealed deposition of stoichiometric <TEX>$Ga_2O_3$</TEX> thin films at 500-600 <TEX>$^{\circ}C$</TEX>. XPS depth profiling by <TEX>$Ar^+$</TEX> ion sputtering indicated that carbon contamination exists mostly in the surface region with less than 3.5% content in the film. Microscopic images of the films by scanning electron microscopy (SEM) and atomic force microscopy (AFM) showed formation of grains of approximately 20-40 nm in size on the film surfaces. The root-mean-square surface roughness from an AFM image was <TEX>${\sim}10{\AA}$</TEX>. The interfacial layer of the <TEX>$Ga_2O_3$</TEX>/Si was measured to be <TEX>${\sim}35{\AA}$</TEX> thick by cross-sectional transmission electron microscopy (TEM). From the analysis of gaseous products of the CVD reaction by gas chromatography-mass spectrometry (GC-MS), an effort was made to explain the CVD mechanism.
Relation of body mass index to vitamin D, PTH, and bone turnover markers levels among women in Shanghai area (2013)

Objective To examine the relationship of body mass index (BMI) with levels of vitamin D,parathyroid hormone (PTH),and bone turnover markers among women in Shanghai area.Methods Altogether 810 Chinese women aged 45 year and older were enrolled to study the associations by multiple linear regression analyses.Bone mineral density was measured by a dual energy X-ray absorptiometry (Lunar,Prodigy,GE),Serum 25-hydroxyvitamin D [25 (OH) D],PTH,C-telopeptide of type Ⅰ collagen (CTX),osteocalcin (BGP),and bonespecific alkaline phosphatase (BSALP) were measured.Results (1) 25 (OH) D,BGP,BSALP,and CTX levels were significantly lower in obesity group than in control group ; PTH level was significantly higher in obesity group than in control group.(2) In multiple linear regression analyses,BMI was significantly associated with lower 25 (OH) D (β =-0.017,P =0.006),BGP (β =-0.077,P =0.019),and higher PTH (β =0.025,P =0.000).Conclusions (1) There were siginificant associations between higher BMI and lower 25 (OH) D among women in Shanghai.(2) Serum osteocalcin was associated not only with bone metabolism but also with energy metabolism.

Key words: 
25-hydroxyvitamin D;  Parathyroid hormone;  Body mass index;  Osteocalcin
Cloud Platform Based Automated Security Testing System for Mobile Internet (2015)

With respect to security, the use of various terminals in the mobile Internet environment is problematic.Traditional terminal testing methods cannot simulate actual testing environments; thus, the test results do not accurately reflect the security of terminals. To address this problem, we designed and developed a cloud platform based automated testing system for the mobile Internet. In this system, virtualization and automation technology are utilized to integrate mobile terminals into the cloud platform as a resource, to achieve a novel cloud service called Testing as a Service(Taa S). The system consists of three functional modules: web front-end module, testing environment module, and automated testing module. We adopted the permeable automated testing tool Metasploit to perform security testing. In our test experiments, we selected 100 apps with diverse vulnerability levels, ranging from secure to vulnerable, to perform a series of functional tests. The experimental results show that this system can correctly test both the number of vulnerable apps and their corresponding vulnerability levels. As such, the designed system can flexibly configure various testing environments for different testing cases or projects, and thereby perform security testing automatically.
Summary of User Agent Accessibility Guidelines (2001)

This informative appendix summarizes the principal goals and structure of User Agent Accessibility Guidelines 1.0 [UAAG10] .
Physiologic Functions of Cyclophilin D and the Mitochondrial Permeability Transition Pore (2013)

This review focuses on the role of cyclophilin D (CypD) as a prominent mediator of the mitochondrial permeability transition pore (MPTP) and subsequent effects on cardiovascular physiology and pathology. Although a great number of reviews have been written on the MPTP and its effects on cell death, we focus on the biology surrounding CypD itself and the non-cell death physiologic functions of the MPTP. A greater understanding of the physiologic functions of the MPTP and its regulation by CypD will likely suggest novel therapeutic approaches for cardiovascular disease, both dependent and independent of programmed necrotic cell death mechanisms.
Design of solids with free-form surfaces (1983)

We propose a unified method of generating a wide range of three dimensional objects from polyhedra to solids with free-form surfaces. Modeling systems for polyhedra and systems for free-form surfaces have been developed independently in the past because of the difference in their underlying theory and practices. However, this is not desirable for a designer. So in this paper, we have shown a method in which a wide range of shapes are generated in one system by using local modifications. Local modifications are procedures used to change the shape of solids locally. The construction and the modification of three dimensional shapes by these procedures are natural and easy for a designer in many cases. The implementation of these procedures in a computer is easy and their execution does not require much time.
A varactor configuration minimizing the amplitude-to-phase noise conversion in VCOs (2006)

Amplitude-to-phase-noise conversion due to varactors can severely limit the close-in phase noise performance in LC-tuned oscillators. This work proposes a rigorous analysis of this phenomenon, which highlights the fundamental limitations of single-ended tuned and differentially tuned diode varactor configurations. The back-to-back varactor topology is identified as a suitable solution to linearize the tank capacitance. The amplitude to phase noise conversion is greatly attenuated and the 1/f <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> phase noise is drastically reduced, without impairing the achievable tuning range. These results are validated through circuit simulations in an existing 0.35-mum CMOS technology
Transcutaneous Pulsed Radiofrequency Treatment for Patients with Shoulder Pain Booked for Surgery: A Double‐Blind, Randomized Controlled Trial (2013)

Shoulder pain is the third most common musculoskeletal problem and accounts for 5% of general practitioner consultations. Although many treatments are described, there is no consensus on optimal treatment and up to 40% of patients still have pain 12 months after initially seeking help for pain. Previously, the effect of transcutaneous pulsed radiofrequency treatment (TCPRFT) was evaluated in a retrospective audit that showed good pain relief for a mean 395 days and justified this randomized sham controlled trial. In this study, 51 patients entered into a randomized double-blinded, placebo controlled study of TCPRFT. Patients were assessed at 4 and 12 weeks by a blinded observer and compared with baseline. We observed sustained reductions in pain at night, pain with activity, and functional improvement at 4 and 12 weeks with active but not sham TCPRFT. The 25 subjects who received active treatment showed statistically significant reductions of 24/100 in pain at night and 20/100 of pain with activity at 4 weeks and 18/100 and 19/100, respectively, at 12 weeks from baseline. Statistically significant lower Brief Pain Inventory pain and function scores (4 and 12 weeks), improved pain self-efficacy (4 weeks), Oxford Shoulder scores (12 weeks), and internal rotation (12 weeks) were seen. Pain at both rest and shoulder elevation were not improved by active treatment. No complications were seen. This study of a simple, low risk, outpatient treatment confirms the findings of our earlier study of TCPRFT for knee pain and shoulder pain audit that transcutaneous pulsed radiofrequency treatment may help some people with painful shoulders.
MMP Inhibition in Abdominal Aortic Aneurysms: Rationale for a Prospective Randomized Clinical Trial (1999)

Abdominal aortic aneurysms (AAAs) represent a chronic degenerative condition associated with a life-threatening risk of rupture. The evolution of AAAs is thought to involve the progressive degradation of aortic wall elastin and collagen, and increased local production of several matrix metallo-proteinases (MMPs) has been implicated in this process. We have previously shown that tetracycline derivatives and other MMP inhibitors suppress aneurysm development in experimental animal models of AAA. Doxycycline also reduces the expression of MMP-2 and MMP-9 by human vascular wall cell types and by AAA tissue explants in vitro. To determine whether this strategy might have a role in the clinical management of small AAA, we examined the effect of doxycycline on aortic wall MMP expression in vivo. Patients were treated with doxycycline (100 mg p.o. bid) for 7 days prior to elective AAA repair, and aneurysm tissues were obtained at the time of surgery (n = 5). Tissues obtained from an equal number of untreated patients with AAA were used for comparison. By reverse transcription-polymerase chain reaction and Southern blot analysis, MMP-2 and MMP-9 were both found to be abundantly expressed in the aneurysm wall. Preoperative treatment with doxycycline was associated with a 3-fold reduction in aortic wall expression of MMP-2 and a 4-fold reduction in MMP-9 (p < 0.05 compared to untreated AAA). These preliminary results suggest that even short-term treatment with doxycycline can suppress MMP expression within human AAA tissues. Given its pleiotropic effects as an MMP inhibitor, doxycycline may be particularly effective in suppressing aortic wall connective tissue degradation. While it remains to be determined whether MMP inhibition will have a clinically significant impact on aneurysm expansion, it is expected that this question can be resolved by a properly designed prospective randomized clinical trial.
Service provisioning and pricing methods in a multi-tenant cloud enabled RAN (2016)

The Cloud Enabled Small Cell (CESC) concept proposed in EU funded project SESAME has emerged as a promising solution to form a multi-tenant, multi-service architecture at the network edge according to 5G needs. It allows several operators/service providers to engage in a sharing model of both radio access capacity and Mobile Edge Computing (MEC) capabilities. From a business perspective, the shared ecosystem guarantees benefits such as easy system upgrades and CAPEX/OPEX reduction. However, depending on the adapted model which is reflected at Service Level Agreement (SLA) between involved stakeholders, cost and benefit of each party are subject to change. This paper is an effort to identify and analyse different radio and cloud models and pricing schemes for the joint provisioning of radio access capacity and MEC services in a multi-tenant Radio Access Network (RAN).
The theoretical status of latent variables. (2003)

This article examines the theoretical status of latent variables as used in modern test theory models. First, it is argued that a consistent interpretation of such models requires a realist ontology for latent variables. Second, the relation between latent variables and their indicators is discussed. It is maintained that this relation can be interpreted as a causal one but that in measurement models for interindividual differences the relation does not apply to the level of the individual person. To substantiate intraindividual causal conclusions, one must explicitly represent individual level processes in the measurement model. Several research strategies that may be useful in this respect are discussed, and a typology of constructs is proposed on the basis of this analysis. The need to link individual processes to latent variable models for interindividual differences is emphasized.
Characterization of the reproduction of influenza A epidemic viruses in cell cultures. (1986)

Two influenza A epidemic viruses with different indices of virulence for humans have been compared with respect to their reproduction in human embryo kidney (HEK), human embryo lung (HEL), and chick embryo kidney (CEK) cell cultures. It has been shown that the highly virulent for humans A/Victoria/35/72 (H3N2) strain reproduced intensively in HEK and HEL cells irrespective of the inoculated dose (multiplicity of infection = 1 EID50 per cell and of 0.001 EID50 per cell, respectively). Efficient infection of a moderately virulent virus A/Bangkok/1/79 (H3N2) was registered in these cell cultures only after addition of trypsin to the maintenance medium. The viruses tested exhibited essentially no difference as to the intensity of their reproduction in CEK cell culture whose sensitivity remained unchanged after addition of trypsin to the maintenance medium.