gebhart/patrepeval huggingface dataset:
The effects of replacement fly ash with diatomite in geopolymer mortar (2012)

This article presents the effect of replacement fly ash (FA) with diatomite (DE) on the properties of geopolymer mortars. DE was used to partially replace FA at the levels of 0, 60, 80 and 100% by weight of binder. Sodium silicate (<TEX>$Na_2SiO_3$</TEX>) and sodium hydroxide (NaOH) solutions were used as the liquid portion in the mixture in order to activate the geopolymerization. The NaOH concentrations of 15M, <TEX>$Na_2SiO_3$</TEX>/NaOH ratios of 1.5 by weight, and the alkaline liquid/binder (LB) ratios by weight of 0.40, 0.50, 0.60 and 0.70 were used. The curing at temperature of <TEX>$75^{\circ}C$</TEX> for 24 h was used to accelerate the geopolymerization. The flows of all fresh geopolymer mortars were tested. The compressive strengths and the stress-strain characteristics of the mortar at the age of 7 days, and the unit weights were also tested. The results revealed that the use of DE to replace part of FA as source material in making geopolymer mortars resulted in the increased in the workability, and strain capacity of mortar specimens and in the reductions in the unit weights and compressive strengths. The strain capacity of the mortar increased from 0.0028 to 0.0150 with the increase in the DE replacement levels from 0 to 100%. The mixes with 15M NaOH, <TEX>$Na_2SiO_3$</TEX>/NaOH of 1.5, LB ratio of 0.50, and using <TEX>$75^{\circ}C$</TEX> curing temperature showed 7 days compressive strengths 22.0-81.0 MPa which are in the range of normal to high strength mortars.
Let there be color! (2016)

We present a novel technique to automatically colorize grayscale images that combines both global priors and local image features. Based on Convolutional Neural Networks, our deep network features a fusion layer that allows us to elegantly merge local information dependent on small image patches with global priors computed using the entire image. The entire framework, including the global and local priors as well as the colorization model, is trained in an end-to-end fashion. Furthermore, our architecture can process images of any resolution, unlike most existing approaches based on CNN. We leverage an existing large-scale scene classification database to train our model, exploiting the class labels of the dataset to more efficiently and discriminatively learn the global priors. We validate our approach with a user study and compare against the state of the art, where we show significant improvements. Furthermore, we demonstrate our method extensively on many different types of images, including black-and-white photography from over a hundred years ago, and show realistic colorizations.
Multi-agent simulation for balancing of assembly lines (2003)

One of the main applications of simulation is in manufacturing systems. The complexity of this kind of systems is related to the number of decisions that must be taken in shorter time. The main difficulty is to predict the effects of decisions on the overall system performance. In this context simulation becomes an important tool by means of which it is possible to predict the future performance of the system, and so compare and analyse different decisions. The actual discrete-event simulation scenario reveals a systematic demand for more sophisticated and powerful computational tools in order to fulfil the increasing problem of complexity. Computer network technology provides the computational power needed. The combination of distributed simulation with that of multi-agent systems presents a very interesting perspective to design and develop such kinds of environments. We propose an architecture based on multi-agent simulation to help solving problems in balancing and distributing the human resources in manual assembly lines, and in the future we hope to extend the model to other kinds of manufacturing systems.
Chitinase, b-1,3-Glucanase, Osmotin, and Extensin Are Expressed in Tobacco Explants during Flower Formation (1990)

Alan D. Neale, Jill A. Wahleithner, Marianne Lund, Howard T. Bonnett, Alan Kelly, D. Ry Meeks-Wagner, W. James Peacock, Elizabeth S. Dennis, Chitinase, β-1,3-Glucanase, Osmotin, and Extensin Are Expressed in Tobacco Explants during Flower Formation, The Plant Cell, Vol. 2, No. 7 (Jul., 1990), pp. 673-684
A measurement analysis of Internet traffic over frame relay (1999)

Various approaches have been proposed and implemented to relieve the congestion in the Public Switched Telephone Networks (PSTNs) induced by recent meteoric growth of Internet services. The Internet/Intranet Transport Service (IITS) offered by the Southwestern Bell Telephone (SWBT) Company provides an example of one such implementation which off-loads the long-holding time data traffic from PSTNs to a packet technology (in this case Frame Relay).This paper describes analysis of 1997 IITS traffic jointly performed by SWBT and Bellcore with the goal of gaining insights into the nature of the Internet traffic over the Frame Relay technology, and deriving practical traffic engineering guidelines for efficiently managing the network elements to provide Quality-of-Service (QoS) to customers. The analysis was carried out at the frame level as well as the call level. The results demonstrate that traffic (both frame and byte count processes) at the frame level is self-similar with long-range dependent characteristics, while call arrivals are inhomogeneous Poisson processes and call holding times have heavy tails. Frame size statistics are explored, revealing a packet fragmentation issue that can unnecessarily decrease resource efficiency. The impacts of load balancing schemes (implemented by the equipment suppliers) on the traffic characteristics is also observed.
Doubly Robust Policy Evaluation and Learning (2011)

We study decision making in environments where the reward is only partially observed, but can be modeled as a function of an action and an observed context. This setting, known as contextual bandits, encompasses a wide variety of applications including health-care policy and Internet advertising. A central task is evaluation of a new policy given historic data consisting of contexts, actions and received rewards. The key challenge is that the past data typically does not faithfully represent proportions of actions taken by a new policy. Previous approaches rely either on models of rewards or models of the past policy. The former are plagued by a large bias whereas the latter have a large variance. In this work, we leverage the strength and overcome the weaknesses of the two approaches by applying the doubly robust technique to the problems of policy evaluation and optimization. We prove that this approach yields accurate value estimates when we have either a good (but not necessarily consistent) model of rewards or a good (but not necessarily consistent) model of past policy. Extensive empirical comparison demonstrates that the doubly robust approach uniformly improves over existing techniques, achieving both lower variance in value estimation and better policies. As such, we expect the doubly robust approach to become common practice.
On the trail of intrusions into information systems (2000)

The importance of information system security, particularly as it applies to the Internet, is obvious. Each day the news media report yet another security breach-sometimes a localized single crime or prank at others, a denial-of-service attack affecting millions of people. As electronic commerce becomes increasingly pervasive, the subject can only become more critical. One of the more interesting techniques for enhancing information system security is detecting that an intrusion has taken place. Although intrusion-detection systems have been a part of the information security landscape for over 25 years, their proper role in the overall security picture is often misunderstood. They are not preventative security measures. Most often, they are used as active security mechanisms in conjunction with other (passive) information assurance processes like firewalls, smart cards, and virtual private networks. In practice, an intrusion-detection system (IDS) attempts to detect attacks or attack preparations by monitoring either the traffic on a computer network or the application or operating system activities within a computer. Once such behavior is detected, the IDS may alert a security administrator or it may invoke an automated response (such as closing down external communication paths or initiating a mechanism to trace the source of an attack). If an IDS detects attack behavior soon enough, it might be able to invoke a response to thwart the attack.
Alendronate and Estrogen–Progestin in the Long-Term Prevention of Bone Loss: Four-Year Results from the Early Postmenopausal Intervention Cohort Study: A Randomized, Controlled Trial (1999)

Four years of treatment with alendronate or estrogen-progestin prevented postmenopausal bone loss. A residual effect was seen 2 years after alendronate therapy was stopped; however, continuous alendronate treatment was more effective in preventing postmenopausal bone loss than 2 years of alendronate followed by 2 years of placebo.
Characterization of the hematopoietic defect in paroxysmal nocturnal hemoglobinuria. (1986)

We studied the relationship between paroxysmal nocturnal hemoglobinuria (PNH) and bone marrow failure using in vitro hematopoietic colony culture assays. Most of 17 patients with PNH showed decreased colony formation, by erythroid burst-forming cells (BFU-E) and granulocyte-macrophage colony-forming cells (CFU-C) in methylcellulose, disproportionate to their degree of bone marrow biopsy cellularity. Only a minority of the hematopoietic progenitors were sensitive to complement-mediated lysis in vitro. In contrast, normoblasts from maturing erythroid bursts removed from culture and exposed to acidified serum were sensitive to complement-mediated lysis. The size of bursts and the sensitivity of their progeny correlated strongly, suggesting that the PNH defect was acquired in culture as a function of the generational age of erythroid precursor cells. In addition, BFU-E of PNH patients were very sensitive to 3H-thymidine suicide, in comparison with normal individuals and patients with other hemolytic anemias, indicating that a large proportion of primitive erythroid progenitors in PNH bone marrow were in cell cycle. All of these results imply that acquisition of the PNH defect during erythropoiesis may lead to intramedullary destruction of developing erythroid cells. The increased demand that results on the progenitor pool may lead to stem cell depletion and bone marrow failure.
Preparation and characterization of flame retardant epoxy resins based on phosphorus-containing biphenyl-type phenolic resin (2010)

Abstract A phosphorus-containing biphenyl-type phenolic resin (PBP) was prepared by dehydration polycondensation of the DOPO-disubstituted 4,4’- biphenyldimethanol compound (BDCA-2DOPO) with phenol in the presence of strong Lewis acid , in which BDCA-2DOPO was prepared by the reaction of DOPO with 4,4'-biphenyldicarboxaldehyde. The PBP resin has been evaluated as the curing agent of o-cresol epoxy resins. Experimental results indicated that the PBPcured epoxy resins exhibited good thermal stability, high char yields at 700 oC and outstanding flame retardant properties. UL 94 V-0 classifications could be obtained when the phosphorus loading in the epoxy resin is higher than 1.8 wt%.
Fast Assembly of Ordered Block Copolymer Nanostructures through Microwave Annealing (2010)

Block copolymer self-assembly is an innovative technology capable of patterning technologically relevant substrates with nanoscale precision for a range of applications from integrated circuit fabrication to tissue interfacing, for example. In this article, we demonstrate a microwave-based method of rapidly inducing order in block copolymer structures. The technique involves the usage of a commercial microwave reactor to anneal block copolymer films in the presence of appropriate solvents, and we explore the effect of various parameters over the polymer assembly speed and defect density. The approach is applied to the commonly used poly(styrene)-b-poly(methyl methacrylate) (PS-b-PMMA) and poly(styrene)-b-poly(2-vinylpyridine) (PS-b-P2VP) families of block copolymers, and it is found that the substrate resistivity, solvent environment, and anneal temperature all critically influence the self-assembly process. For selected systems, highly ordered patterns were achieved in less than 3 min. In addition, we establish the compatibility of the technique with directed assembly by graphoepitaxy.
Benefits and risks of interferon therapy for hepatitis B # (2009)

Peginterferon alfa has a place as first-line therapy of hepatitis B in patients who are carefully selected on the basis of pretreatment serum HBV DNA and aminotransferase levels, safety considerations, and viral genotype.
Immunological Aspects of Mammary Involution (1989)

Frequency of new intramammary infection is greatest during early involution, decreases during middle stages, and then increases prepartum. Penetrability of the teat canal, antibacterial properties of keratin, bacterial adherence, and epithelial sensitivity to toxins play a role in resistance. Leukocytes phagocytose bacteria and regulate expression of immune mechanisms, although their function is compromised during certain stages of involution. These cells increase to millions per milliliter as involution progresses and then decrease prepartum. Macrophages predominate in lacteal secretions, followed by lymphocytes and neutrophils. Lactoferrin, a major whey protein and iron chelator, is also associated with resistance to infection during the nonlactating period and may have immunomodulatory properties. Lacteal immunoglobulins increase throughout involution peaking prepartum and function by opsonizing bacteria, neutralizing toxins, and preventing bacterial adherence. Immunoglobulins are derived from blood or are produced locally by plasma cells present in the subepithelial mammary stroma. Plasma cells, lymphoid cells, and other protective leukocytes present in teat end tissues accumulate during infection and concentrations increase in response to local antigenic stimulation. Various aspects of the mammary immune system are compromised during periods of functional transition. Thus, vaccination, immunostimulation, accelerated involution, and intramammary devices are some methods now being tested to amplify local immunity and protect the gland from bacterial infection.
Mechanisms of Cellular Invasiveness: A Comparison of Amnion Invasion In Vitro and Metastatic Behavior In Vivo (1989)

We employed a sensitive in vitro amnion invasion assay to examine the relationship of the invasive ability of numerous mouse and human tumor cell lines and their variants to their ability to spontaneously or artificially metastasize; we also studied possible enzymatic activities involved in the in vitro invasion process. In vitro invasive ability of tumor cells was strongly correlated with spontaneous metastatic ability from the subcutaneous site, regardless of the ability of tumor cells to form artificial metastases when introduced intravenously. However, normal nontumorigenic human trophoblast cells were also highly invasive. Various collagenase inhibitors totally abrogated amnion penetration by all invasive cells; various inhibitors of plasmin, plasminogen, and plasminogen activators prevented invasion in most, but not all, cases. Thus, amnion penetration provides a rigorous test for tumor cell invasiveness required for spontaneous metastasis in vivo, and invasiveness is strongly dependent on metalloproteinase activity, which usually follows plasmin activation.
The use of the L-plastin promoter for adenoviral-mediated, tumor-specific gene expression in ovarian and bladder cancer cell lines. (2001)

A 2.4-kb truncated L-plastin promoter was inserted either 5' to the LacZ gene (Ad-Lp-LacZ) or 5' to the cytosine deaminase (CD) gene (Ad-Lp-CD) in a replication-incompetent adenoviral vector backbone. Infectivity and cytotoxicity experiments with the LacZ and CD vectors suggested that the L-plastin promoter-driven transcriptional units were expressed at much higher levels in explants of ovarian cancer cells from patients and in established ovarian or bladder cancer cell lines than they were in normal peritoneal mesothelial cells from surgical specimens, in organ cultures of normal ovarian cells, or in the established CCD minimal deviation fibroblast cell line. Control experiments showed that this difference was not attributable to the lack of infectivity of the normal peritoneal cells, the normal ovarian cells, or the minimal deviation CCD fibroblast cell line, because these cells showed expression of the LacZ reporter gene when exposed to the replication-incompetent adenoviral vector carrying the cytomegalovirus (CMV)-driven LacZ gene (Ad-CMV-LacZ). The Ovcar-5 and Skov-3 ovarian cancer cell lines exposed to the Ad-Lp-CD adenoviral vector were much more sensitive to the prodrug 5-fluorocytosine (5FC), which is converted from the 5FC prodrug into the toxic chemical 5-fluorouracil, than was the CCD minimal deviation fibroblast cell line after exposure to the same vector. A mouse xenograft model was used to show that the Ad-Lp-CD vector/5FC system could prevent engraftment of ovarian cancer cells in nude mice. Finally, injection of the Ad-Lp-CD vector into s.c. tumor nodules generated a greater reduction of the size of the tumor nodules than did injection of the Ad-CMV-LacZ vectors into tumor nodules. The Ad-Lp-CD vectors were as suppressive to tumor growth as the Ad-CMV-CD vectors. These results suggest that an adenoviral vector carrying the CD gene controlled by the L-plastin promoter (Ad-Lp-CD) may be of potential value for the i.p. therapy of ovarian cancer.
Design space exploration using arithmetic-level hardware--software cosimulation for configurable multiprocessor platforms (2006)

Configurable multiprocessor platforms consist of multiple soft processors configured on FPGA devices. They have become an attractive choice for implementing many computing applications. In addition to the various ways of distributing software execution among the multiple soft processors, the application designer can customize soft processors and the connections between them in order to improve the performance of the applications running on the multiprocessor platform. State-of-the-art design tools rely on low-level simulation to explore the various design trade-offs offered by configurable multiprocessor platforms. These low-level simulation based exploration techniques are too time-consuming and can be a major bottleneck to efficient design space exploration on these platforms. We propose a design space exploration technique for configurable multiprocessor platforms using arithmetic-level cycle-accurate hardware--software cosimulation. Arithmetic-level abstractions of the hardware and software execution platforms are created within the proposed cosimulation environment. The configurable multiprocessor platforms are described using these arithmetic-level abstractions. Hardware and software simulators are tightly integrated to concurrently simulate the arithmetic behavior of the multiprocessor platform. The simulation within the integrated simulators are synchronized to provide cycle-accurate simulation results for the complete multiprocessor platform. By doing so, we significantly speed up the cosimulation process for configurable multiprocessor platforms. Exploration of the various hardware-software design trade-offs provided by configurable multiprocessor platforms can be performed within the proposed cycle-accurate cosimulation environment. After the final designs are identified, the corresponding low-level implementations with the desired cycle-accurate arithmetic behavior are generated automatically. For illustrative purposes, we provide an implementation of our approach based on MATLAB/Simulink. We show the cosimulation of two numerical computation applications and one image-processing application on a popular configurable multiprocessor platform within the MATLAB/Simulink-based cosimulation environment. For these three applications, our arithmetic-level cosimulation approach leads to speed-ups in simulation time of up to more than 800x compared with the low-level simulation approaches. The designs of these applications identified using our arithmetic-level cosimulation approach achieve execution time speed-ups up to 5.6x, compared with other designs considered in our experiments.
Mango Supplementation Improves Blood Glucose in Obese Individuals (2014)

This pilot study examined the effects of freeze-dried mango (Mangifera indica L.) supplementation on anthropometrics, body composition, and biochemical parameters in obese individuals. Twenty obese adults (11 males and 9 females) ages 20- to 50-years old, received 10 g/day of ground freeze-dried mango pulp for 12 weeks. Anthropometrics, biochemical parameters, and body composition were assessed at baseline and final visits of the study. After 12 weeks, mango supplementation significantly reduced blood glucose in both male (-4.45 mg/dL, P = 0.018) and female (-3.56 mg/dL, P = 0.003) participants. In addition, hip circumference was reduced in male (-3.3 cm, P = 0.048) but not in female participants. However, there were no significant changes in body weight or composition in either gender. Our findings indicate that regular consumption of freeze-dried mango by obese individuals does not negatively impact body weight but provides a positive effect on fasting blood glucose.
Recombinant derivatives of the human high‐mobility group protein HMGB2 mediate efficient nonviral gene delivery (2005)

Certain natural peptides and proteins of mammalian origin are able to bind and condense plasmid DNA, a prerequisite for the formation of transfection-competent complexes that facilitate nonviral gene delivery. Here we have generated recombinant derivatives of the human high-mobility group (HMG) protein HMGB2 and investigated their potential as novel protein-based transfection reagents. A truncated form of HMGB2 encompassing amino acids 1-186 of the molecule was expressed in Escherichia coli at high yield. This HMGB2186 protein purified from bacterial lysates was able to condense plasmid DNA in a concentration-dependent manner, and mediated gene delivery into different established tumor cell lines more efficiently than poly(l-lysine). By attaching, via gene fusion, additional functional domains such as the HIV-1 TAT protein transduction domain (TAT(PTD)-HMGB2186), the nuclear localization sequence of the simian virus 40 (SV40) large T-antigen (SV40(NLS)-HMGB2186), or the importin-beta-binding domain (IBB) of human importin-alpha (IBB-HMGB2186), chimeric fusion proteins were produced which displayed markedly improved transfection efficiency. Addition of chloroquine strongly enhanced gene transfer by all four HMGB2186 derivatives studied, indicating cellular uptake of protein-DNA complexes via endocytosis. The IBB-HMGB2186 molecule in the presence of the endosomolytic reagent was the most effective. Our results show that recombinant derivatives of human HMGB2 facilitate efficient nonviral gene delivery and may become useful reagents for applications in gene therapy.
Automatic synthesis of behavior protocols for composable web-services (2009)

Web-services are broadly considered as an effective means to achieve interoperability between heterogeneous parties of a business process and offer an open platform for developing new composite web-services out of existing ones. In the literature many approaches have been proposed with the aim to automatically compose web-services. All of them assume that, along with the web-service signature, some information is provided about how clients interacting with the web-service should behave when invoking it.
Asynchronous Sampling And Reconstruction Of Sparse Signals (2012)

Publication in the conference proceedings of EUSIPCO, Bucharest, Romania, 2012