gebhart/patrepeval huggingface dataset:
Performance Characteristics of Micro-cathode Arc Thruster (2013)

This paper describes measurements of performance characteristics of micro-cathode arc thruster. In particular, influence of an applied magnetic field on the impulse bit, specific impulse, and the mass consumption is investigated. The micro-cathode arc thruster was operated in a quasi-steady-state mode to ensure that a measurable thrust stand deflection was produced. It was found that the impulse bit increases from about in the case without a magnetic field up to about in the case of a magnetic field of about 0.3 T. A magnetic field leads to an increase of the mass consumption from about at zero magnetic field up to about at a magnetic field of about 0.3 T. Average ion velocity is measured to be about (at ) and about (at ). Maximum efficiency of the thruster is estimated to be about 7%.
Device and method for transforming light energy into electrical energy (2008)

The invention relates to a device comprising a reactor, where the reactor comprises an anode compartment and a cathode compartment, and where the anode compartment comprises a) an anodophilic micro-organism capable of oxidizing an electron donor compound, and b) a living plant or part thereof. The invention also relates to a method for converting light energy into electrical energy and/or hydrogen, where a feedstock comprising an electron donor compound is introduced into the device.
Immunological and Protective Effects of Diepitopic Subunit Dental Caries Vaccines (2005)

As a prelude to development of broader-spectrum vaccines for dental caries, we explored the immune potential of constructs combining epitopes from mutans streptococcal glucosyltransferases (GTF) and glucan binding protein B (GbpB). Two diepitopic peptide constructs were synthesized in a multiple antigenic peptide (MAP) format. Both constructs contained SYI, a 20-mer GbpB peptide that included a sequence having major histocompatibility complex class II binding characteristics. One diepitopic construct (SYI-CAT) also contained a 22-mer sequence from the catalytic domain of GTF. Another diepitopic construct (SYI-GLU) contained a 22-mer sequence from the glucan binding domain of GTF. To assess the ability of each construct to induce antibody reactive with GbpB and GTF native proteins, rats were injected subcutaneously with SYI-CAT, SYI-GLU, or the constituent monoepitopic constructs. Only the SYI-CAT construct induced significant levels of serum immunoglobulin G (IgG) and IgA antibody to both pathogenesis-associated proteins. Also, immunization with SYI-CAT significantly (P < 0.001) enhanced the antibody response to the CAT peptide. Experiments then compared experimental dental caries after immunization with SYI-CAT, SYI, or CAT MAP constructs, followed by infection with Streptococcus mutans strain SJr. Dental caries were lower in each peptide-immunized group than in the sham-injected group. The level of protection after SYI-CAT immunization was similar to that after immunization with constituent MAP constructs. In another experiment, rats were infected with Streptococcus sobrinus strain 6715 under an identical protocol. Significant protection was observed on buccal surfaces in both SYI-CAT and CAT construct-immunized, but not in the SYI construct-immunized, groups. Thus, addition of the GbpB-derived SYI peptide to the GTF-derived CAT peptide construct not only enhanced the immunological response to CAT and GTF epitopes, but also extended the protective effect of the construct to include both S. mutans and S. sobrinus.
THz transceiver characterization : LDRD project 139363 final report. (2009)

LDRD Project 139363 supported experiments to quantify the performance characteristics of monolithically integrated Schottky diode + quantum cascade laser (QCL) heterodyne mixers at terahertz (THz) frequencies. These integrated mixers are the first all-semiconductor THz devices to successfully incorporate a rectifying diode directly into the optical waveguide of a QCL, obviating the conventional optical coupling between a THz local oscillator and rectifier in a heterodyne mixer system. This integrated mixer was shown to function as a true heterodyne receiver of an externally received THz signal, a breakthrough which may lead to more widespread acceptance of this new THz technology paradigm. In addition, questions about QCL mode shifting in response to temperature, bias, and external feedback, and to what extent internal frequency locking can improve stability have been answered under this project.
Updates to the Fast Reroute Procedures for Co-routed Associated Bidirectional Label Switched Paths (LSPs) (2019)

Resource Reservation Protocol (RSVP) association signaling can be used
to bind two unidirectional Label Switched Paths (LSPs) into an
associated bidirectional LSP. When an associated bidirectional LSP is
co-routed, the reverse LSP follows the same path as its forward LSP.
This document updates the Fast Reroute (FRR) procedures defined in RFC
4090 to support both single-sided and double-sided provisioned
associated bidirectional LSPs. This document also updates the
procedure for associating two reverse LSPs defined in RFC 7551 to
support co-routed bidirectional LSPs. The FRR procedures can ensure
that for the co-routed LSPs, traffic flows on co-routed paths in the
forward and reverse directions after a failure event.
16-wavelength gain-coupled DFB laser array with fine tunability (1996)

16-wavelength semiconductor laser array with fine wavelength tunability is demonstrated, utilizing gain-coupled distributed feedback (DFB) lasers with different ridge waveguide widths. Besides the coarse tuning by the ridge widths, the fine post-fabrication tunability for individual lasers in the array is achieved with a Ti thin-film resistor integrated on the chip. Due to the gain-coupling effect, 16 single-mode lasing wavelengths around 1.55 μm in /spl sim/1 nm spacing are obtained simultaneously. An effective fine-tuning up to 1 nm is observed at a moderate heating power of 100 mW.
Method for preparing a thick film conductor. [Patent application] (1977)

A method for preparing a thick film conductor is described which comprises providing surface active glass particles, mixing the surface active glass particles with a thermally decomposable organometallic compound, for example, a silver resinate, and then decomposing the organometallic compound by heating, thereby chemically depositing metal on the glass particles. The glass particle mixture is applied to a suitable substrate either before or after the organometallic compound is thermally decomposed. The resulting system is then fired in an oxidizing atmosphere, providing a microstructure of glass particles substantially uniformly coated with metal.
Comparing human to electronic observers to monitor hand hygiene compliance in an intensive care unit (2022)

The electronic HH monitoring system had good correlation with human HH observation, but compliance was remarkably lower when human observers were not present due to the Hawthorne effect (25%-30% absolute difference). Electronic monitoring systems can replace direct observation and can markedly reduce the Hawthorne effect.
Floating Body Ring Termination for Trench Field Plate Power MOSFETs (2020)

The active regions of a trench field plate power MOSFET experience RESURF which is essentially 2-D in nature and can be easily optimized. However, for the same design parameters, the 3-D regions in the device termination can experience significantly weakened RESURF causing them to become the bottleneck for breakdown, thus undermining the 2-D optimization. To strengthen the RESURF in the termination, floating body rings between the active and the termination regions are introduced. Through the coupling of these floating rings, the body in the termination acquires a voltage bias which strengthens the RESURF and increases the breakdown voltage. The working principles of this design are discussed, and the concept is verified through 3-D TCAD simulations.
Compositions involving CR sub 2 -O sub 3 V sub 2 O sub 3 -TiO sub 2 (1991)

This patent describes a method of preparing a composition from Cr{sub 2}O{sub 3}, V{sub 2}O{sub 3} and TiO{sub 2} wherein the composition falls within the shaded area circumscribed by ABCDF as shown in the disclosed FIGURE. It comprises heating V{sub 2}O{sub 5} powder having a particle size of less than about 50 microns in an atmosphere in which the partial pressure of oxygen is in the range of 10{sup {minus}8} to 10{sup {minus}10} atmospheres while starting at a temperature of 600{degrees} C and gradually increasing the temperature over a period in the range of about 12 to 24 hours to about 1300{degrees} C for a period to ensure complete reduction of all vanadium to V{sup 3+}; separately heating TiO{sub 2} and Cr{sub 2}O{sub 3} powders each having a particle size of less than about 50 microns for a period of about 10 to 14 hrs at a temperature in the range of about 600{degrees} C to 800{degrees} C for TiO{sub 2} and about 1000{degrees} C to 1200{degrees} C for Cr{sub 2}O{sub 3}; thoroughly grinding together about 35 to 98 wt. % of V{sub 2}O{sub 3} from, with about 0 to 55 wt. % of TiO{sub 2} and about 2 tomore » 45 wt. % of Cr{sub 2}O{sub 3} to produce a mixture having a grain size of less than about 50 microns; pelletizing the mixture at a pressure of about 5,000 psi; and heating and reacting together the pellets at a temperature in the range of about 1100{degrees} C to 1800{degrees} C for a period in the range of about 1/2 to 48 hrs in an atmosphere in which the partial pressure of oxygen is in the range of 10{sup {minus}10} to 10{sup {minus}5} atmosphere. This patent also describes composition produced from Cr{sub 2}O{sub 3}, V{sub 2}O{sub 3} and TiO{sub 2}, wherein the composition is a solid solution.« less
Efficacy of Dapagliflozin in Black Versus White Patients With Heart Failure and Reduced Ejection Fraction (2021)

Dapagliflozin reduced the risk of worsening HF and cardiovascular death, and it improved symptoms, similarly in Black and White patients without an increase in adverse events. (Study to Evaluate the Effect of Dapagliflozin on the Incidence of Worsening Heart Failure or Cardiovascular Death in Patients With Chronic Heart Failure [DAPA-HF]; NCT03036124).
Synchrophasors for island detection (2012)

Detection and prevention of unintentional islands powered by distributed generators like photovoltaics remains a key concern of utility protection engineers, especially in high-penetration and grid-support environments. These evolving circumstances dictate that new island detection tools are needed. Synchrophasors are highly promising in this regard, but some in the community remain skeptical about them due to costs. This paper discusses synchrophasors, how they may be used to detect islands, their cost-reducing value-added features, and synchrophasor-based island detection methods.
New GMP manufacturing processes to obtain thermostable HIV-1 gp41 virosomes under solid forms for various mucosal vaccination routes (2020)

The main objective of the MACIVIVA European consortium was to develop new Good Manufacturing Practice pilot lines for manufacturing thermostable vaccines with stabilized antigens on influenza virosomes as enveloped virus-like particles. The HIV-1 gp41-derived antigens anchored in the virosome membrane, along with the adjuvant 3M-052 (TLR7/8 agonist) on the same particle, served as a candidate vaccine for the proof of concept for establishing manufacturing processes, which can be directly applied or adapted to other virosomal vaccines or lipid-based particles. Heat spray-dried powders suitable for nasal or oral delivery, and freeze-dried sublingual tablets were successfully developed as solid dosage forms for mucosal vaccination. The antigenic properties of vaccinal antigens with key gp41 epitopes were maintained, preserving the original immunogenicity of the starting liquid form, and also when solid forms were exposed to high temperature (40 °C) for up to 3 months, with minimal antigen and adjuvant content variation. Virosomes reconstituted from the powder forms remained as free particles with similar size, virosome uptake by antigen-presenting cells in vitro was comparable to virosomes from the liquid form, and the presence of excipients specific to each solid form did not prevent virosome transport to the draining lymph nodes of immunized mice. Virosome integrity was also preserved during exposure to <-15 °C, mimicking accidental freezing conditions. These "ready to use and all-in-one" thermostable needle-free virosomal HIV-1 mucosal vaccines offer the advantage of simplified logistics with a lower dependence on the cold chain during shipments and distribution.
ChemInform Abstract: CATION‐RADICAL CATALYZED DIELS‐ALDER REACTION (1981)

Abstract In Gegenwart des Am iniumsalzes steigt die Ausb. an Dimer (I) des Diens (II) bei einem endo‐exo‐Verhältnis von 30% (20 h, 200°C) auf 70% (15 min, 0°C) an.
The Broad-Spectrum Tospovirus Resistance Gene <i>Sw-5</i> of Tomato Is a Homolog of the Root-Knot Nematode Resistance Gene <i>Mi</i> (2000)

We used a positional cloning approach to isolate the Sw-5 disease resistance locus of tomato. Complementation experiments with overlapping cosmid clones enabled us to demonstrate that Sw-5 is a single gene locus capable of recognizing several tospovirus isolates and species. Analysis of the predicted Sw-5 protein suggests that it is a cytoplasmic protein, with a potential nucleotide binding site (NBS) domain and a C-terminal end consisting of leucine-rich repeats (LRRs). Based on its structural features, Sw-5 belongs to the class of NBS-LRR resistance genes that includes the tomato Mi, 12, and Prf genes; the Arabidopsis RPM1 gene; and the plant potato virus X resistance gene Rx. The overall similarity between the Sw-5 and Mi proteins of tomato suggests that a shared or comparable signal transduction pathway leads to both virus and nematode resistance in tomato. The similarity also supports the hypothesis that Sw-5 provides resistance via a hypersensitive response. Sw-5 is a member of a loosely clustered gene family in the telomeric region of chromosome 9. Members of this family map to other regions of chromosome 9 and also to chromosome 12, where several fungal, virus, and nematode genes have been mapped, suggesting that paralogs of Sw-5 may have evolved to provide different resistance specificities.
No-carrier-added [1.sup.11 c]putrescine (1989)

The invention relates to a new radiolabeled imaging agent, no-carrier-added [1-.sup.11 C]putrescine, and to the use of this very pure material as a radiotracer with positron emission tomography for imaging brain tumors. The invention further relates to the synthesis of no-carrier-added [1-.sup.11 C]putrescine based on the Michael addition of potassium .sup.11 C-labeled cyanide to acrylonitrile followed by reduction of the .sup.11 C-labeled dinitrile. The new method is rapid and efficient and provides radiotracer with a specific activity greater than 1.4 curies per millimol and in a purity greater than 95%.
Ultrasensitive solution-processed broad-band photodetectors using CH<sub>3</sub>NH<sub>3</sub>PbI<sub>3</sub>perovskite hybrids and PbS quantum dots as light harvesters (2015)

Sensing from ultraviolet-visible to infrared is critical for both scientific and industrial applications. In this work, we demonstrate solution-processed ultrasensitive broad-band photodetectors (PDs) utilizing organolead halide perovskite materials (CH3NH3PbI3) and PbS quantum dots (QDs) as light harvesters. Through passivating the structural defects on the surface of PbS QDs with diminutive molecular-scaled CH3NH3PbI3, both trap states in the bandgap of PbS QDs for charge carrier recombination and the leakage currents occurring at the defect sites are significantly reduced. In addition, CH3NH3PbI3 itself is an excellent light harvester in photovoltaics, which contributes a great photoresponse in the ultraviolet-visible region. Consequently, operated at room temperature, the resultant PDs show a spectral response from 375 nm to 1100 nm, with high responsivities over 300 mA W(-1) and 130 mA W(-1), high detectivities exceeding 10(13) Jones (1 Jones = 1 cm Hz(1/2) W(-1)) and 5 × 10(12) Jones in the visible and near infrared regions, respectively. These device performance parameters are comparable to those from pristine inorganic counterparts. Thus, our results offer a facile and promising route for advancing the performance of broad-band PDs.
ChemInform Abstract: TITANIUM(III) AS A SELECTIVE REDUCING AGENT FOR NITROARGINYL PEPTIDES‐ SYNTHESIS OF ARGININE VASOTOCIN (1979)

Abstract Nitro‐arginyl‐Reste in Peptiden werden durch Ti(III) glatt zu den Arginylresten reduziert.
Inhibition by dietary organoselenium, p-methoxybenzene-selenol, of hepatocarcinogenesis induced by azoxymethane in rats. (1985)

The effect of dietary p-methoxybenzeneselenol, a new organoselenium compound, on azoxymethane (AOM)-induced hepatocarcinogenesis was examined in female F344 rats. Semipurified diets containing 0 and 5 ppm p-methoxybenzeneselenol were fed to the rats, starting at 5 weeks of age until one week after the carcinogen treatment. At 7 weeks of age, all animals except the vehicle-treated controls were given weekly sc injections of AOM (15 mg/kg body weight, 3 times). At 34 weeks after the last AOM treatment, the liver neoplasm incidence and liver tumor multiplicity as well as the incidence of altered liver cell foci were significantly lower in AOM-treated rats fed the diet containing 50 ppm p-methoxybenzeneselenol (tumor incidence 19%, tumor multiplicity 0.45/rat, foci incidence 3.47/cm2) than in AOM-treated animals fed the diet without p-methoxybenzeneselenol (tumor incidence 66%, tumor multiplicity 2.24/rat, foci incidence 12.08/cm2). These results indicate that dietary p-methoxybenzeneselenol at a dose of 50 ppm inhibits AOM-induced hepatic tumorigenesis.
A Novel Class of Succinimide-Derived Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 1 Provides Insight into a Disconnect in Activity between the Rat and Human Receptors (2014)

Recent progress in the discovery of mGlu₁ allosteric modulators has suggested the modulation of mGlu₁ could offer possible treatment for a number of central nervous system disorders; however, the available chemotypes are inadequate to fully investigate the therapeutic potential of mGlu₁ modulation. To address this issue, we used a fluorescence-based high-throughput screening assay to screen an allosteric modulator-biased library of compounds to generate structurally diverse mGlu₁ negative allosteric modulator hits for chemical optimization. Herein, we describe the discovery and characterization of a novel mGlu₁ chemotype. This series of succinimide negative allosteric modulators, exemplified by VU0410425, exhibited potent inhibitory activity at rat mGlu₁ but was, surprisingly, inactive at human mGlu₁. VU0410425 and a set of chemically diverse mGlu₁ negative allosteric modulators previously reported in the literature were utilized to examine this species disconnect between rat and human mGlu₁ activity. Mutation of the key transmembrane domain residue 757 and functional screening of VU0410425 and the literature compounds suggests that amino acid 757 plays a role in the activity of these compounds, but the contribution of the residue is scaffold specific, ranging from critical to minor. The operational model of allosterism was used to estimate the binding affinities of each compound to compare to functional data. This novel series of mGlu₁ negative allosteric modulators provides valuable insight into the pharmacology underlying the disconnect between rat and human mGlu₁ activity, an issue that must be understood to progress the therapeutic potential of allosteric modulators of mGlu₁.
Lithotripsy system having an ultrasonic calculi locator (1990)

First Page
Accumulation of classical monocytes defines a subgroup of MDS that frequently evolves into CMML (2017)

International audience
Tuning the iridescence of chiral nematic cellulose nanocrystals and mesoporous silica films by substrate variation (2013)

We have discovered that the self-assembly of cellulose nanocrystals (CNCs) into chiral nematic phases varies significantly with the substrate and evaporation rate. These variables allow the reflectance peak of iridescent chiral nematic films of CNCs and mesoporous silica templated from CNCs to be tuned over a wide range of wavelengths.
A method to measure impedance of chip/package/board power supply system using pseudo-impulse current (2006)

A method to measure the impedance Z(f) of a chip/package/board power supply system using pseudo-impulse current is described. This method can be easily applied to the digital systems with synchronous clocking systems. A PowerPC based microprocessor power supply system is used as an example to show the effectiveness of the method.
Incremental Frequent Subgraph Mining on Large Evolving Graphs (2018)

Frequent subgraph mining is a core graph operation used in many domains. Most existing techniques target static graphs. However, modern applications utilize large evolving graphs. Mining these graphs using existing techniques is infeasible because of the high computational cost. We propose IncGM+, a fast incremental approach for frequent subgraph mining on large evolving graphs. We adapt the notion of "fringe" to the graph context, that is, the set of subgraphs on the border between frequent and infrequent subgraphs. IncGM+ maintains fringe subgraphs and exploits them to prune the search space. To boost efficiency, IncGM+ stores a number of selected embeddings to avoid redundant expensive subgraph isomorphism operations. Moreover, the proposed system supports batch updates. Our results confirm that IncGM+ outperforms existing methods, scales to larger graphs and consumes less memory.
Complementary dose and geometrical solutions for electron beam direct write lithography proximity effects correction: application for sub-<inline-formula><math altimg="none" display="inline" overflow="scroll"><mrow><mn>45</mn><mtext>-</mtext><mi>nm</mi></mrow></math></inline-formula> node product manufacturing (2007)

After the successful results obtained in the last few years, electron beam direct write (EBDW) lithography for use in integrated circuit manufacturing has now been demonstrated. However, throughput and resolution capabilities need to be improved to push its interest for fast cycle production and advanced research and development applications. In this way, the process development needs good patterns dimensional accuracy, i.e., a better control of the proximity effects caused by backscattering electrons and others phenomenon. In this work, the limitations of the dose modulation method are investigated through the change of dose number steps and the use of a more accurate point spread function. To continue reducing feature sizes, a method to provide a complementary correction to the dose modulation solution is proposed. This rule-based electron beam proximity correction, or REBPC, provides good results down to 40 nm.