gebhart/patrepeval huggingface dataset:
Large-Scale Phased Array Calibration (2019)

One challenge in fielding large-scale phased array antennas is calibration of the antenna system, so that RF radiated beams can be accurately formed and steered. Here, we describe two new methods for calibrating large phased arrays, namely, the mobile Fourier gauge (MFG) and satellite-based calibration (SatCal) that permit rapid calibration of large phased arrays on site and that remove the need for expensive nearfield facility testing that limits the size of the array sections that can be RF aligned. The MFG utilizes a known short RF line source that can be sequentially moved across the array using an existing crane; RF coupling measurements between this RF line source and the array elements made at different RF line source positions are vector summed, so as to form a known virtual RF line source that stretches the length of the array. A second independent method, SatCal, is presented that uses reflections from orbiting satellites to calibrate the array, either at the subarray or radiating element level. These calibration methods have been demonstrated on a large S-band phased array and have resulted in array calibrations equivalent to within 5°, 0.7 dB rms (element level), or 4°, 0.6 dB rms (subarray level).
Multi-gene biomarker panel for reference free prostate cancer diagnosis: determination and independent validation (2010)

Identification of biomarkers that can accurately and reliably diagnose prostate cancer is clinically highly desirable. A novel classification method, K-closest resemblance was applied to several high-quality transcriptomic datasets of prostate cancer leading to the discovery of a panel of eight gene biomarkers that can detect prostate cancer with over 96% specificity and sensitivity in leave-one-out cross-validation. Independent validation on clinical samples confirmed the discriminatory power of this gene panel, yielding over 95% accuracy of diagnosis based on receiver-operating characteristic curve analyses. Different levels of validation of the proposed biomarker panel have shown that it allows extremely accurate diagnosis of prostate cancer. Application of this panel can possibly add a fast and objective tool to the pathologist's arsenal following further clinical testing.
DNA AMPLIFICATION USING TABLETED PCR REAGENTS FOR IDENTIFICATION OF <i>ESCHERICHIA COLI</i> O157:H7 ISOLATED FROM FOODS<sup>1</sup> (1997)

A DNA amplification method using tableted multiplex polymerase chain reaction (PCR) reagents was developed for identification of enterohemorrhagic Escherichia coli (EHEC) serotype O157:H7 isolated from food samples. A suspect colony from MacConkey sorbitol agar containing 5‐bromo‐4‐chloro‐3‐indoxyl‐6‐D‐glucuronide (MSA‐BCIG) was used to perform the PCR. Three different DNA sequences of E. coli O157:H7 were amplified simultaneously in the PCR: a specific fragment of an attaching and effacing gene ( eae gene ), conserved sequences of Shiga‐like toxins (SLT) I and II, and a fragment of the 60‐MDa plasmid. This method detected all reference strains of EHEC serogroup O157, including serotypes O157:H7, O157:NM, and O157:H, and negative results were obtained with all strains of nontoxigenic E. coli serogroup O157, other serotypes of E. coli , and other bacterial species. The detection limit of the method was 950 colony forming units (CFU) of E. coli O157:H7. All 29 cultures of EHEC O157:H7 isolated from meat samples and identified by biochemical and serological tests were positive in the PCR. After a 6‐h enrichment, EHEC O157:H7 was identified from all experimentally inoculated ground beef and milk samples which had initial inocula of 4 to 9 CFU/g (mL). This method offers significant advantages in terms of technical simplicity and reproducibility of test results over conventional PCR and other assays for detecting E. coli serotype O157 and should be suitable for use in routine examination of food and other samples for the presence of the pathogen.
Efficient Compression of Hyperspectral Images by Grouping around Lines (2006)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation I. Gladkova, N. Nalli, W. Wolf, L. Zhou, M. Goldberg, L. Roytman; Efficient Compression of Hyperspectral Images by Grouping around Lines. AIP Conf. Proc. 4 October 2006; 860 (1): 321–330. https://doi.org/10.1063/1.2361234 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioAIP Conference Proceedings Search Advanced Search |Citation Search
Sequence analysis of a functional member of the Em gene family from wheat (1991)

We report the complete sequence of one functional member of the Em gene family whose expression in wheat embryos is regulated by a complex set of environmental and developmental controls, including the phytohormone abscisic acid (ABA). The Em coding region contains one short intron, and there is an inverted repeat in the transcribed 3'-flanking region. A 646 bp fragment from the 5' promoter, which was previously shown to direct ABA-regulated expression in transformed tobacco tissue and rice cells, is characterized by: (1) three stretches of between 33 and 73 nucleotides of A/T rich (greater than 86%) boxes, (2) one copy of an eight bp palindrome (CATGCATG) which is identical to the RY repeat found in the 5' promoters of many legume genes expressed during embryo development, (3) 15 copies of a six bp repeat (PuCACGPy), found primarily in the 5' region, and (4) two sequences in the ABA-response region, CGAGCAG and a CACGT motif, both of which are conserved in 5' non-coding regions of other plant genes that are expressed in response to ABA and/or in embryos. These sequence comparisons are discussed in relation to the regulation of Em gene expression and other ABA-regulated genes.
High performance long-wave type-II superlattice infrared detectors (2013)

The authors report on growth, material characterization, and device performance of infrared photodetectors based on type II InAs/GaSb superlattices using the complementary barrier infrared detector (CBIRD) design. In this paper, control steps for improvement of material quality in terms of surface, structural, and optical properties of infrared detectors grown at Jet Propulsion Laboratory are described. For a specific CBIRD studied, these quality control steps indicate high structural and optical quality of the grown material. Furthermore, single-element detector from the optimized growth conditions exhibit dark current density less than 1 × 10−5 A/cm2 at applied biases up to Vb = 0.36 V (T = 77 K), so this material can be utilized for focal plane arrays development.
Phenyl‐ and Biphenylylbicyclo[2.2.2]octane Derivatives—Two Novel Classes of Nematic Liquid Crystals (1981)

The novel liquid crystals (1) and (2) containing a bicyclo[2.2.2]octane group are characterized, inter alia, by the fact that the nematic phase occurs at higher temperatures and over a greater temperature range than in the case of the analogous compounds containing a benzene or cyclohexane ring instead of the bicycle.
Melt fracture and wall slip of thermoplastic vulcanizates (2020)

Abstract Thermoplastic vulcanizates (TPVs) are blends of polypropylene (PP) (thermoplastic phase) and ethylene propylene diene monomer (EPDM) rubber (rubber phase) in which a high content of rubber EPDM is cross‐linked and dispersed in a thermoplastic matrix (PP) in the presence of oil (lubricant) and filler. Depending on the molecular characteristics of the constituent polymers, the level of curing and the amount of cross‐linked rubber, their processing (extrusion) exhibits various difficulties such as melt fracture (extrudate distortions). In this study, a number of different TPVs with various characteristics, including the degree of curing and amount of cross‐linked rubber are examined in capillary extrusion at two different temperatures (190°C and 205°C) relevant to real processing. First, the effect of the temperature on the yield stress is investigated using rheological measurements. Consequently, the flow behavior of the TPVs in capillary flow is studied concluding that TPVs slip massively (nearly plug flow) due to the presence of lubricant and the vulcanized rubber phase. Although there is little slip observed in PP samples, EPDMs themselves exhibit severe slip and melt fracture. As a consequence, the TPV samples essentially follow the slip behavior of EPDMs. Finally, the melt fracture analysis of several TPVs has shown that with increase of temperature and amount of cross‐linked rubber, the severity of TPVs' surface defects increases accordingly.
Self‐Assembled Injectable Nanocomposite Hydrogels Stabilized by Bisphosphonate‐Magnesium (Mg<sup>2+</sup>) Coordination Regulates the Differentiation of Encapsulated Stem Cells via Dual Crosslinking (2017)

Nanocomposite hydrogels consist of a polymer matrix embedded with nanoparticles (NPs), which provide the hydrogels with unique bioactivities and mechanical properties. Incorporation of NPs via in situ precipitation in the polymer matrix further enhances these desirable hydrogel properties. However, the noncytocompatible pH, osmolality, and lengthy duration typically required for such in situ precipitation strategies preclude cell encapsulation in the resultant hydrogels. Bisphosphonate (BP) exhibits a variety of specific bioactivities and excellent binding affinity to multivalent cations such as magnesium ions (Mg 2+ ). Here, the preparation of nanocomposite hydrogels via self‐assembly driven by bisphosphonate‐Mg 2+ coordination is described. Upon mixing solutions of polymer bearing BPs, BP monomer (Ac‐BP), and Mg 2+ , this effective and dynamic coordination leads to the rapid self‐assembly of Ac‐BP‐Mg NPs which function as multivalent crosslinkers stabilize the resultant hydrogel structure at physiological pH. The obtained nanocomposite hydrogels are self‐healing and exhibit improved mechanical properties compared to hydrogels prepared by blending prefabricated NPs. Importantly, the hydrogels in this study allow the encapsulation of cells and subsequent injection without compromising the viability of seeded cells. Furthermore, the acrylate groups on the surface of Ac‐BP‐Mg NPs enable facile temporal control over the stiffness and crosslinking density of hydrogels via UV‐induced secondary crosslinking, and it is found that the delayed introduction of this secondary crosslinking enhances cell spreading and osteogenesis.
The Cation Selectivity Filter of the Bacterial Sodium Channel, NaChBac (2002)

The Bacillus halodurans voltage-gated sodium-selective channel (NaChBac) (Ren, D., B. Navarro, H. Xu, L. Yue, Q. Shi, and D.E. Clapham. 2001b. SCIENCE: 294:2372-2375), is an ideal candidate for high resolution structural studies because it can be expressed in mammalian cells and its functional properties studied in detail. It has the added advantage of being a single six transmembrane (6TM) orthologue of a single repeat of mammalian voltage-gated Ca(2+) (Ca(V)) and Na(+) (Na(V)) channels. Here we report that six amino acids in the pore domain (LESWAS) participate in the selectivity filter. Replacing the amino acid residues adjacent to glutamatic acid (E) by a negatively charged aspartate (D; LEDWAS) converted the Na(+)-selective NaChBac to a Ca(2+)- and Na(+)-permeant channel. When additional aspartates were incorporated (LDDWAD), the mutant channel resulted in a highly expressing voltage-gated Ca(2+)-selective conductance.
Significance of Dosimetry in Photodynamic Therapy of Injured Arteries: Classification of Biological Responses (1999)

With conflicting results in the literature on the ability of photodynamic therapy (PDT) to inhibit intimal hyperplasia (IH), the present study systematically investigated the effects of drug and light dosimetry on the biologic responses in the artery wall. The rat common carotid artery was balloon-injured and pressurized with benzoporphyrin-derivative monoacid ring (BPD). Then, PDT was performed with an external laser at different fluences and the biologic responses of the artery wall were histologically examined at 24 h and at 2 weeks. Photodynamic therapy effects on injured arteries can be classified into four stages: low-dose PDT using 0.5 microgram/mL BPD at 50 J/cm2 (stage I) resulted in incomplete cell eradication and significant IH at 2 weeks. Irradiation with 100 J/cm2 at the same BPD concentration (stage II) completely eradicated the cells in the artery wall at 24 h but still led to IH at 2 weeks. However, 25 micrograms/mL BPD at 100 J/cm2 (stage III) resulted in total cell eradication at 24 h and inhibition of IH at 2 weeks. In contrast, high-dose PDT with 25 micrograms/mL BPD and 200 J/cm2 (stage IV) led to thrombus development and vascular occlusion at 24 h. These data, demonstrating the different stages of PDT effects on injured arteries, emphasize the critical importance of appropriate PDT dosimetry for the effective inhibition of IH.
Diagnosis of Tuberculosis Based on the Two Specific Antigens ESAT-6 and CFP10 (2000)

Tests based on tuberculin purified protein derivative (PPD) cannot distinguish between tuberculosis infection, Mycobacterium bovis BCG vaccination, or exposure to environmental mycobacteria. The present study investigated the diagnostic potential of two Mycobacterium tuberculosis-specific antigens (ESAT-6 and CFP10) in experimental animals as well as during natural infection in humans and cattle. Both antigens were frequently recognized in vivo and in vitro based on the induction of delayed-type hypersensitivity responses and the ability to induce gamma interferon production by lymphocytes, respectively. The combination of ESAT-6 and CFP10 was found to be highly sensitive and specific for both in vivo and in vitro diagnosis. In humans, the combination had a high sensitivity (73%) and a much higher specificity (93%) than PPD (7%).
Concentration-Dependent Vascularization of Adipose Stromal Vascular Fraction Cells (2015)

Adipose-derived stromal vascular fraction (SVF) cells have been shown to self-associate to form vascular structures under both in vitro and in vivo conditions. The angiogenic (new vessels from existing vessels) and vasculogenic (new vessels through self-assembly) potential of the SVF cell population may provide a cell source for directly treating (i.e., point of care without further cell isolation) ischemic tissues. However the correct dosage of adipose SVF cells required to achieve a functional vasculature has not been established. Accordingly, in vitro and in vivo dose response assays were performed evaluating the SVF cell vasculogenic potential. Serial dilutions of freshly isolated rat adipose SVF cells were plated on growth factor reduced Matrigel and vasculogenesis, assessed as cellular tube-like network assembly, was quantified after 3 days of culture. This in vitro vasculogenesis assay indicated that rat SVF cells reached maximum network length at a concentration of 2.5 × 10(5) cells/ml and network maintained at the higher concentrations tested. The same concentrations of rat and human SVF cells were used to evaluate vasculogenesis in vivo. SVF cells were incorporated into collagen gels and subcutaneously implanted into Rag1 immunodeficient mice. The 3D confocal images of harvested constructs were evaluated to quantify dose dependency of SVF cell vasculogenesis potential. Rat- and human-derived SVF cells yielded a maximum vasculogenic potential at 1 × 10(6) and 4 × 10(6) cells/ml, respectively. No adverse reactions (e.g., toxicity, necrosis, tumor formation) were observed at any concentration tested. In conclusion, the vasculogenic potential of adipose-derived SVF cell populations is dose dependent.
Management of Cocaine Abuse and Dependence (1996)

During the 20th century, there have been recurrent episodes of cocaine abuse in the United States that have achieved epidemic proportions.1 Although the total number of people using the drug has decreased in the past decade, cocaine-related biomedical and psychosocial problems remain a major public health problem in the United States and many other countries. The expanding list of cocaine-related toxic effects, acute and chronic, includes reproductive dysfunction, hepatic necrosis, and pulmonary disease.2 Abuse of and dependence on cocaine may also be associated with disorders of sexual function, sleep, anxiety, and mood, as well as with delirium and psychotic disorders. . . .
Crystal structure of CspA, the major cold shock protein of Escherichia coli. (1994)

The major cold shock protein of Escherichia coli, CspA, produced upon a rapid downshift in growth temperature, is involved in the transcriptional regulation of at least two genes. The protein shares high homology with the nucleic acid-binding domain of the Y-box factors, a family of eukaryotic proteins involved in transcriptional and translational regulation. The crystal structure of CspA has been determined at 2-A resolution and refined to R = 0.187. CspA is composed of five antiparallel beta-strands forming a closed five-stranded beta-barrel. The three-dimensional structure of CspA is similar to that of the major cold shock protein of Bacillus subtilis, CspB, which has recently been determined at 2.45-A resolution. However, in contrast to CspB, no dimer is formed in the crystal. The surface of CspA is characteristic for a protein interacting with single-stranded nucleic acids. Due to the high homology of the bacterial cold shock proteins with the Y-box factors, E. coli CspA and B. subtilis CspB define a structural framework for the common cold shock domain.
Design of a lanthanum bromide detector for time-of-flight PET (2004)

Recent improvements in the growth and packaging of lanthanum bromide (LaBr/sub 3/), in addition to its superb intrinsic properties of high light output, excellent energy resolution, and fast decay time, make it a viable detection material for a positron emission tomography (PET) scanner based on time-of-flight (TOF). We have utilized theoretical simulations and experimental measurements to investigate the design and performance of pixelated LaBr/sub 3/ Anger-logic detectors suitable for use in a TOF PET scanner. Our results indicate that excellent energy resolution can be obtained from individual as well as multicrystal arrays of LaBr/sub 3/ in a 4 mm/spl times/4 mm /spl times/ 30 mm geometry. Measured energy resolutions (at 511 keV) of 4.1% for a single crystal and an average of 5.1% for an array of 100 crystals have been achieved with our best samples. Both simulations and experimental measurements of an Anger-logic based detector consisting of the LaBr/sub 3/ crystal array coupled to a continuous light guide and seven photomultiplier tubes (PMTs), have resulted in the ability to clearly discriminate 511 keV interactions in each crystal. We have measured coincidence time resolutions for both 0.5% and 5.0% cerium-doped LaBr/sub 3/ and found that the higher level of Ce-doping yielded superior results with little to no degradation in light output or energy resolution. The time resolution for a single 5.0% Ce-doped LaBr/sub 3/ crystal (4 mm /spl times/ 4 mm /spl times/ 30 mm) coupled directly to a PMT was measured to be 275 ps full-width at half-maximum (FWHM). With an array of 100 crystals coupled to a light guide and seven PMT cluster an average time resolution of 290 ps FWHM was obtained by summing the signals from the PMT cluster. Ultimately, two 5.0% Ce-doped LaBr/sub 3/ Anger-logic detectors placed in coincidence yielded a time resolution of 313 ps FWHM.
An MRF-Based DeInterlacing Algorithm With Exemplar-Based Refinement (2009)

In this paper, we propose an MRF-based deinterlacing algorithm that combines the benefits of rule-based algorithms such as motion-adaptation, edge-directed interpolation, and motion compensation, with those of an MRF formulation. MRF-based interpolation and enhancement algorithms are typically formulated as an optimization over pixel intensities or colors, which can make them relatively slow. In comparison, our MRF-based deinterlacing algorithm uses interpolation functions as labels.We use seven interpolants (three spatial, three temporal, and one for motion compensation). The core dynamic programming algorithm is, therefore, sped up greatly over the direct use of intensity as labels. We also show how an exemplar-based learning algorithm can be used to refine the output of our MRF-based algorithm. The training set can be augmented with exemplars from static regions of the same video, as a form of "self-learning."
Concrete volute pumps: technology review and improvement (2012)

When pumps need to deliver large water flow rates (typically more than 5 m3.s−1), concrete volute pumps (CVP) offer an interesting alternative to standard vertical wet-pit pumps. One of the major advantages of CVP is its simplicity in terms of design, manufacturability and maintainability. In addition, CVP geometrical arrangement allows to reach high performances in terms of hydraulic and mechanical behaviour. These advantages can be specifically appreciated when such pumps are used in the energy field for Power Plants which need high flow rate and reliability, and can lead to important financial savings over the Plant lifetime compared to vertical wet-pit pumps. Finally, as CVP was for a long time limited to total head rise lower than 30 mWC, it was established through CFD analysis that the addition of guide vanes between the impeller and the volute allows to achieve higher head rise without risk.
Mercury in Biological Fluids after Amalgam Removal (1998)

Dental amalgam is the major source of inorganic mercury (Hg) exposure in the general population. The objective of the present study was to obtain data on changes in Hg levels in blood, plasma, and urine following removal of all amalgam fillings during one dental session in 12 healthy subjects. The mean number of amalgam surfaces was 18 (range, 13 to 34). Frequent blood sampling and 24-hour urine collections were performed up to 115 days after amalgam removal, and in eight subjects additional samples of plasma and urine were collected up to three years after amalgam removal. A transient increase of Hg concentrations in blood and plasma was observed within 48 hours after amalgam removal. In plasma, the peak concentrations significantly exceeded the pre-removal plasma Hg levels by, on average, 32% (1.3 nmol/L; range, 0.1 to 4.2). No increase in the urinary Hg excretion rate was apparent after amalgam removal. An exponential decline of Hg was seen in all media. Sixty days after the amalgam removal, the Hg levels in blood, plasma, and urine had declined to approximately 60% of the pre-removal levels. In seven subjects, who were followed for up to three years, the half-lives of Hg in plasma and urine were calculated. In plasma, a bi-exponential model was applied, and the half-life was estimated at median 88 days (range, 21 to 121). The kinetics of Hg in urine (nmol/24 hrs) fit a mono-exponential model with a median half-life of 46 days (range, 35 to 67). It is concluded that the process of removing amalgam fillings can have a considerable impact on Hg levels in biological fluids. After removal, there was a considerable decline in the Hg levels of blood, plasma, and urine, which slowly approached those of subjects without any history of amalgam fillings.