Capillary Zone Electrophoresis as A Tool for Bottom-Up Protein Analysis (2015)

BioanalysisVol. 8, No. 2 CommentaryCapillary zone electrophoresis as a tool for bottom-up protein analysisRoza Wojcik, Guijie Zhu, Zhenbin Zhang, Xiaojing Yan, Yimeng Zhao, Liangliang Sun, Matthew M Champion & Norman J DovichiRoza Wojcik Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA, Guijie Zhu Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA, Zhenbin Zhang Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA, Xiaojing Yan Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA, Yimeng Zhao Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA, Liangliang Sun Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA, Matthew M Champion Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA & Norman J Dovichi*Author for correspondence: E-mail Address: ndovichi@nd.edu Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USAPublished Online:10 Dec 2015https://doi.org/10.4155/bio.15.227AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinkedInReddit View articleKeywords: bottom-up proteomicscapillary electrophoresisproteomicsReferences1 Smith RD, Barinaga CJ, Udseth HR. 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Pediatrics 129(2), e356–363 (2012).Crossref, Medline, Google ScholarFiguresReferencesRelatedDetailsCited ByNeutral-Coating Capillary Electrophoresis Coupled with High-Resolution Mass Spectrometry for Top-Down Identification of Hemoglobin Variants29 October 2022 | Clinical Chemistry, Vol. 69, No. 1Capillary electrophoresis as a powerful tool for the analyses of bacterial samplesTrAC Trends in Analytical Chemistry, Vol. 134Single-Shot Capillary Zone Electrophoresis–Tandem Mass Spectrometry Produces over 4400 Phosphopeptide Identifications from a 220 ng Sample10 June 2019 | Journal of Proteome Research, Vol. 18, No. 8Middle-down approach: a choice to sequence and characterize proteins/proteomes by mass spectrometry1 January 2019 | RSC Advances, Vol. 9, No. 1Recent developments and applications of capillary and microchip electrophoresis in proteomics and peptidomics (2015-mid 2018)28 November 2018 | Journal of Separation Science, Vol. 42, No. 1Capillary zone electrophoresis-mass spectrometry for bottom-up proteomicsTrAC Trends in Analytical Chemistry, Vol. 108Recent developments in capillary and microchip electroseparations of peptides (2015-mid 2017)25 September 2017 | ELECTROPHORESIS, Vol. 39, No. 1A Comprehensive Guide for Performing Sample Preparation and Top-Down Protein Analysis7 April 2017 | Proteomes, Vol. 5, No. 4Recent advances in protein analysis by capillary and microchip electrophoresis1 January 2017 | The Analyst, Vol. 142, No. 11Coupling Capillary Zone Electrophoresis to a Q Exactive HF Mass Spectrometer for Top-down Proteomics: 580 Proteoform Identifications from Yeast25 August 2016 | Journal of Proteome Research, Vol. 15, No. 10 Vol. 8, No. 2 Follow us on social media for the latest updates Metrics Downloaded 220 times History Published online 10 December 2015 Published in print January 2016 Information© Future Science LtdKeywordsbottom-up proteomicscapillary electrophoresisproteomicsFinancial & competing interests disclosureThis work was supported by a grant from the NIH (R01GM096767). R Wojcik, L Sun, G Zhu and NJ Dovichi disclose that patents have been filed and that they receive royalties on the electrospray interfaces mentioned in this manuscript. The authors have no other relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript apart from those disclosed.No writing assistance was utilized in the production of this manuscript.PDF download