gebhart/patrepeval huggingface dataset:
Body talk (2016)

Realistic, metrically accurate, 3D human avatars are useful for games, shopping, virtual reality, and health applications. Such avatars are not in wide use because solutions for creating them from high-end scanners, low-cost range cameras, and tailoring measurements all have limitations. Here we propose a simple solution and show that it is surprisingly accurate. We use crowdsourcing to generate attribute ratings of 3D body shapes corresponding to standard linguistic descriptions of 3D shape. We then learn a linear function relating these ratings to 3D human shape parameters. Given an image of a new body, we again turn to the crowd for ratings of the body shape. The collection of linguistic ratings of a photograph provides remarkably strong constraints on the metric 3D shape. We call the process crowdshaping and show that our Body Talk system produces shapes that are perceptually indistinguishable from bodies created from high-resolution scans and that the metric accuracy is sufficient for many tasks. This makes body "scanning" practical without a scanner, opening up new applications including database search, visualization, and extracting avatars from books.
Dual Catalytic Synthesis of Antiviral Compounds Based on Metallocarbene–Azide Cascade Chemistry (2018)

Aryl azides trap ortho-metallocarbene intermediates to generate indolenones possessing a reactive C-acylimine moiety, which can react with added indole nucleophiles to afford the 2-(3-indolyl)indolin-3-one scaffold found in the antiviral natural product isatisine A. This overall process occurs through a dual catalytic sequence at room temperature. Redox activation of the Cu(OTf)<sub>2</sub> precatalyst by indole results in catalytically competent Cu(I) required for azide-metallocarbene coupling. The Brønsted acid that is also formed from Cu(OTf)<sub>2</sub> reduction is responsible for catalysis of the C-C bond-forming indole addition step. This modular, procedurally simple method allows for rapid assembly of bis(indole) libraries, several of which proved to have anti-infective activity against respiratory syncytial virus and Zika virus.
Characterizing the Molecular Pathology of Arrhythmogenic Cardiomyopathy in Patient Buccal Mucosa Cells (2016)

Buccal mucosa cells from arrhythmogenic cardiomyopathy patients exhibit changes in the distribution of cell junction proteins similar to those seen in the heart. These cells may prove useful in future studies of disease mechanisms and drug screens for effective therapies in arrhythmogenic cardiomyopathy.
enzyme immobilization on biomaterial surfaces for prevention of pseudomonas aeruginosa biofilms (2016)

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Survival and Reproduction of Artificially Fed Cat Fleas, Ctenocephalides felis Bouché (Siphonaptera: Pulicidae) (1988)

Journal Article Survival and Reproduction of Artificially Fed Cat Fleas, Ctenocephalides felis Bouché (Siphonaptera: Pulicidae) Get access Susan E. Wade, Susan E. Wade Department of Veterinary Microbiology, Immunology, and Parasitology, New York State College of Veterinary Medicine, Cornell University, Ithaca, New York 14853 Search for other works by this author on: Oxford Academic PubMed Google Scholar Jay R. Georgi Jay R. Georgi Department of Veterinary Microbiology, Immunology, and Parasitology, New York State College of Veterinary Medicine, Cornell University, Ithaca, New York 14853 Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Medical Entomology, Volume 25, Issue 3, 1 May 1988, Pages 186–190, https://doi.org/10.1093/jmedent/25.3.186 Published: 01 May 1988 Article history Received: 20 July 1987 Accepted: 15 January 1988 Published: 01 May 1988
Distinct Symptom-Specific Treatment Targets for Circuit-Based Neuromodulation (2020)

Distinct clusters of depressive symptoms responded better to different TMS targets across independent retrospective data sets. These symptom-specific targets can be prospectively tested in a randomized clinical trial. This data-driven approach for identifying symptom-specific targets may prove useful for other disorders and facilitate personalized neuromodulation therapy.
Dipole antenna for underwater radio communications (2016)

The radiation characteristics of a dipole antenna when immersed in both fresh and seawater are assessed through simulation and experimental work. Simulations show that the antenna's bandwidth and radiation pattern change with the properties of the medium where it is placed, namely the conductivity of the medium. Two dipoles antennas with current baluns were built and tested experimentally in freshwater. The tests included the measurement of the insertion loss between two identical dipole antennas and their radiation pattern. The results obtained show a good agreement between the simulation and experimental results.
Field Trial of Distributed Fiber Sensor Network Using Operational Telecom Fiber Cables as Sensing Media (2020)

We demonstrate fiber optic sensing systems in a distributed fiber sensor network built on existing telecom infrastructure to detect temperature, acoustic effects, vehicle traffic, etc. Measurements are also demonstrated with different network topologies and simultaneously sensing four fiber routes with one system.
Caveolin-1 Variant Is Associated With the Metabolic Syndrome in Kuwaiti Children (2018)

Caveolin-1 (<i>CAV1</i>) variants have been suggested to be associated with obesity and related metabolic disorders, but information based on human studies is limited. In the present study, we aimed to investigate the potential association between the <i>CAV1</i> rs1997623 C/A variant and metabolic syndrome (MetS) in Kuwaiti children. DNA from saliva samples collected from 1313 Kuwaiti children (mean age: 12 years) were genotyped using the TaqMan SNP genotyping assay. The classification of MetS was based on the presence/absence of four indicators; (1) central obesity, (2) elevated systolic or diastolic blood pressure, (3) low salivary high-density lipoprotein cholesterol (HDLC), and (4) high salivary glucose. In this study, children with MetS scored ≥3, children in the intermediate metabolic group scored 1 or 2 and children without MetS scored 0. About one-third of the children were obese. A total of 246 children (18.7%) were classified as having MetS; 834 children (63.5%) were in the intermediate metabolic group, and 233 children (17.7%) had no indication of MetS. Obesity was highly prevalent in the MetS group (91.9%) while 26.8% of children were obese in the intermediate metabolic group. None of the children were obese in the group without MetS. Analysis of the <i>CAV1</i> rs1997623 variant revealed a significant association of the A-allele (<i>p</i> = 0.01, Odds Ratio (OR) = 1.66) and the heterozygous CA-genotype (<i>p</i> = 0.005, OR = 1.88) with MetS. Consistently, the A-allele (<i>p</i> = 0.002, OR = 1.71) and CA-genotype (<i>p</i> = 0.005, OR = 1.70) also showed significant association with the intermediate metabolic group. Furthermore, the A-allele (<i>p</i> = 0.01, OR = 1.33) and the CA-genotype (<i>p</i> = 0.008, OR = 1.55) were associated with low levels of saliva HDLC. Individuals who were heterozygous or homozygous for the variant (CA/AA) showed significantly lower levels of high HDLC compared to those harboring the CC-genotype (<i>p</i> = 0.023). Our study revealed a novel association of the <i>CAV1</i> rs1997623 variant with the MetS and with low saliva HDLC levels in young Kuwaiti children and indicated the need for further in-depth studies to unravel the role of <i>CAV1</i> gene in the genetic etiology of MetS.
Dicationic imidazolium-based ionic liquids: a new strategy for non-toxic and antimicrobial materials (2014)

Dicationic imidazolium-based ILs: a potent strategy for applications requiring non-toxic materials with antimicrobial activity.
A new soft red winter wheat cultivar, ‘GA 07353‐14E19’, adapted to Georgia and the U.S. Southeast environments (2021)

Abstract Soft red winter wheat (SRWW) ( Triticum aestivum L.), historically a major crop in Georgia and the U.S. Southeast (SE) region, has been challenged by numerous biotic and abiotic constraints resulting in decreased hectarage in recent years. Hence, an urgent need exists to release new cultivars with high yield potential, good resistance to predominant diseases and insects, and acceptable quality attributes to capture and maximize value in regional markets. The SRWW breeding program at the University of Georgia (UGA), in collaboration with the Southeastern University GRAINS (SUNGRAINS) breeding programs, is responding to these challenges by developing and releasing superior SRWW cultivars adapted to Georgia and the SE wheat region. ‘GA 07353‐14E19’ (Reg. no. CV‐1179, PI 689520), a SRWW cultivar developed by the UGA small grains breeding program, was released by the UGA College of Agricultural and Environmental Sciences and licensed to Stratton Seed Company in 2017 as GO WHEAT 2032. GA 07353‐14E19 is adapted to the SE region with high yield, good resistance to prevalent diseases, including leaf and stripe rusts, Fusarium head blight, powdery mildew, and Soil‐borne wheat mosaic virus . GA 07353‐14E19 also showed good resistance to current biotypes of Hessian fly. GA 07353‐14E19 possesses the H13 , Sbm1 , and Yr17 – Lr37 – Sr38 genes that protect it against the above pests. It has very good grain volume weight and good milling and baking quality as a SRWW.
Quantitative cerebral MR perfusion imaging: Preliminary results in stroke (2010)

This initial evaluation indicates that quantitative MRI perfusion is feasible in ischemic stroke patients. qCBF derived with this strategy provide enhanced discrimination of CI and PP compared to time-based imaging metrics. This approach merits investigation in larger clinical studies.
Intrablock Interleaving for Batched Network Coding With Blockwise Adaptive Recoding (2021)

Batched network coding (BNC) is a low-complexity solution to network transmission in multi-hop packet networks with packet loss. BNC encodes the source data into batches of packets. As a network coding scheme, the intermediate nodes perform recoding on the received packets belonging to the same batch instead of just forwarding them. A recoding scheme that may generate more recoded packets for batches of a higher rank is also called adaptive recoding. Meanwhile, in order to combat burst packet loss, the transmission of a block of batches can be interleaved. Stream interleaving studied in literature achieves the maximum separation among any two consecutive packets of a batch, but permutes packets across blocks and hence cannot bound the buffer size and the latency. To resolve the issue of stream interleaver, we design an intrablock interleaver for adaptive recoding that can preserve the advantages of using a block interleaver when the number of recoded packets is the same for all batches. We use potential energy in classical mechanics to measure the performance of an interleaver, and propose an algorithm to optimize the interleaver with this performance measure. Our problem formulation and algorithm for intrablock interleaving are also of independent interest.
Molecular Cloning, Expression and Characterization of Mouse Leukotriene C<sub>4</sub> Synthase (1996)

Leukotriene C4 synthase (EC 2.5.1.37) catalyzes the conjugation of reduced glutathione (GSH) with leukotriene A4 to form the intracellular parent of the proinflammatory cysteinyl leukotrienes. Human leukotriene C4 synthase shares substantial amino acid identity in its consensus N-terminal two-thirds with 5-lipoxygenase-activating protein and has a region (residues 37-58) that exhibits 46% amino acid identity with a domain of this protein (residues 41 -62) to which an inhibitor binds. We have now cloned mouse leukotriene C4 synthase CDNA using the polymerase chain reaction to screen a mouse pcDNA3 expression library with oligonucleotide primers based on the translated human leukotriene C4 synthase cDNA sequence. Mouse leukotriene C4 synthase cDNA is 667 bp in length, including the poly(A)-rich tail, and shows 87% similarity with the human cDNA within the open reading frame. The deduced 150-amino-acid sequence of mouse leukotriene C4 synthase (differs from the human enzyme by only 18 amino acids, of which 9 reside at the C terminus. The potential N-glycosylation site, two protein kinase C phosphorylation sites, the two cysteine residues, and the putative inhibitor-binding domain (substitutions Thr4l-->Ser and Tyr50-->Phe) were conserved in mouse leukotriene C4 synthase. Northern blot analysis indicated that the leukotriene C4 synthase RNA transcript is widely distributed. The Km values for leukotriene A4 methyl ester, leukotriene A4 free acid and GSH were 7.6 microM, 3.6 microM and 1.6 mM, respectively, for purified human recombinant enzyme, and 10.3 microM, 2.5 microM and 1.9 microM, respectively, for purified recombinant mouse enzyme; the corresponding Vmax values were 2.5, 1.3 and 2.7 micromol x min(-1) x mg(-1) protein, respectively, for human enzyme, and 2.3, 1.2 and 2.2 micromol x min(-1) x mg(-1) protein, respectively, for mouse enzyme. The 5-lipoxygenase-activating-protein inhibitor, MK-886, was active against both human and mouse recombinant leukotriene C4 synthase with IC50 values of 3.1 microM and 2.7 microM respectively. These findings confirm that the leukotriene C4 synthases belong to a gene family that includes the 5-lypoxygenase-activating protein and suggest that the C-terminal domain of leukotriene C4 synthase may not be critical for its conjugation function.
Computer simulated fragmentation arena test for assessing lethality and safety separation distances of explosive fragmentation ammunitions (2007)

A combined analytical and experimental technique for determining explosive fragmentation ammunition safe separation distance and lethality without costly arena fragmentation tests is presented. The new methodology integrates high-strain high-strain-rate computer modelling with semi-empirical analytical fragmentation modelling and experimentation, offering warhead designers and ammunition developers more ammunition performance information for less money spent. The new method provides more detailed and accurate warhead fragmentation data for ammunition safe separation distance analysis, as compared to the traditional fragmentation arena testing approach.
Initiated Chemical Vapor Deposition of Linear and Cross-linked Poly(2-hydroxyethyl methacrylate) for Use as Thin-Film Hydrogels (2005)

Initiated chemical vapor deposition (iCVD) is able to synthesize linear and cross-linked poly(2-hydroxyethyl methacrylate) (PHEMA) thin films, in one step, from vapors of 2-hydroxyethyl methacrylate (HEMA), ethylene glycol diacrylate (EGDA), and tert-butyl peroxide (TBPO) without using any solvents. This all-dry technique also allows control of the cross-link density by adjusting the partial pressure of the cross-linking agent EGDA in the vapor phase. Films with specific cross-link densities and hence thermal, wetting, and swelling properties can be created in one single vacuum processing step. Through selective thermal decomposition of the initiator TBPO, films with well-defined chemical structures and full functionality retention can be deposited, which is evident in the Fourier transform infrared (FTIR) and X-ray photoelectron spectroscopy (XPS) analyses. These spectroscopic methods also facilitate determination of EGDA incorporation in the cross-linked films based on the fact that HEMA contains a hydroxyl group but EGDA does not. For the linear PHEMA depositions, the growth rate was found to be nonlinear in the partial pressure of HEMA, possibly due to nonlinear multilayer adsorption and/or primary termination. The EGDA/HEMA ratio in the films systematically increased from 0.00 to 0.46 as the EGDA partial pressure was raised. The onset temperatures of decomposition were between 270 and 302 degrees C for the linear and the most cross-linked films, respectively. Thermal annealing at approximately 430 degrees C resulted in minuscule amounts of residue for all films, linear or cross-linked. The most cross-linked film had approximately 99.50% thickness removed after annealing. The contact angle was found to increase with increasing cross-link density. Significant contact-angle hysteresis was observed, indicating surface reconfiguration, and the lowest receding angle was 17 degrees for the linear film. Swelling measurements using spectroscopic ellipsometry showed that the degree of swelling decreased with increasing EGDA incorporation. The water content decreased from 35% (v/v) for the linear film to below 10% (v/v) for the most cross-linked film. These results show that iCVD is able to produce PHEMA thin films that function as hydrogels when soaked in water. The spectroscopic results, the contact-angle results, and the swelling analysis altogether prove the retention of the hydrophilic pendant groups in the iCVD process.
High-performance flexible pentacene transistor memory with PTCDI-C<sub>13</sub> as N-type buffer layer (2022)

Abstract Flexible organic field-effect transistor nonvolatile memories (OFET-NVMs) with polymer electrets have aroused great attention for its important role in next-generation flexible data storage devices application. However, the OFET-NVMs to date still hardly reach the requirements for practical applications. In air environment, the positively charged defects formed in pentacene near the interface with polymer, result in unsatisfied high programming/erasing (P/E) voltages. Here, we propose an OFET memory structure, in which an n-type semiconductor N, N′-Bis(3-pentyl) perylene-3, 4, 9, 10-bis(dicarboximide) (PTCDI-C 13 ) is inserted between pentacene and poly(4-vinyl phenol. Based on the electrostatic induction effect, electrons are induced on the surface of PTCDI-C 13 due to the electrostatic field generated by the positive charges at the interface of pentacene/polymer, and compensate part of the positive charges at the interface, resulting in the reduction of the height of hole-barrier. The flexible memory device with PTCDI-C 13 exhibits a memory window of larger than 7 V at P/E voltages (±20 V), fast switching speeds (0.5 ms), good P/E endurance (>400 cycles), large field-effect mobility (0.026 cm 2 V −1 s −1 ), and long retention time (over 10 4 s).
Chemically bonded phosphate ceramics for low‐level mixed‐waste stabilization (1997)

Abstract Novel chemically bonded phosphate ceramics are being developed and fabricated for low‐temperature stabilization and solidification of mixed‐waste streams that are not amenable to conventional high‐temperature stabilization processes because volatiles, such as heavy‐metal chlorides and fluorides, and/or pyrophorics are present in the wastes. Phosphates of Mg, Mg‐Na, and Zr are being developed as candidate matrix materials. In this paper, we present the fabrication procedures for phosphate waste forms with surrogate compositions of three typical mixed‐waste streams, namely ash, cement sludges, and salts. This study was focused, but not limited to, magnesium phosphate‐ash wastestream final waste form. The performance of the final waste forms, such as compression strength, leachability of the contaminants, and durability in aqueous environments were conducted. In addition, parametric studies have been conducted to establish the optimal ash waste loading in the magnesium phosphate binder system. Based on the results, we present potential applications of phosphate‐bonded ceramics in the treatment of various mixed‐waste streams.
Noncontact phase-sensitive dynamic optical coherence elastography at megahertz rate (2016)

Dynamic optical coherence elastography (OCE) techniques have shown great promise at quantitatively obtaining the biomechanical properties of tissue. However, the majority of these techniques have required multiple temporal OCT acquisitions (M-B mode) and corresponding excitations, which lead to clinically unfeasible acquisition times and potential tissue damage. Furthermore, the large data sets and extended laser exposures hinder their translation to the clinic, where patient discomfort and safety are critical criteria. In this work we demonstrate noncontact true kilohertz frame-rate dynamic optical coherence elastography by directly imaging a focused air-pulse induced elastic wave with a home-built phase-sensitive OCE system based on a 4X buffered Fourier Domain Mode Locked swept source laser with an A-scan rate of ~1.5 MHz. The elastic wave was imaged at a frame rate of ~7.3 kHz using only a single excitation. In contrast to previous techniques, successive B-scans were acquired over the measurement region (B-M mode) in this work. The feasibility of this method was validated by quantifying the elasticity of tissue-mimicking agar phantoms as well as porcine corneas ex vivo at different intraocular pressures. The results demonstrate that this method can acquire a depth-resolved elastogram in milliseconds. The reduced data set enabled a rapid elasticity assessment, and the ultra-fast acquisition speed allowed for a clinically safe laser exposure to the cornea.
Biochemical and Molecular Studies of Human Methenyltetrahydrofolate Synthetase (1996)

5-FormylH(4)folate is administered clinically under the name Leucovorintrade mark in association with the antineoplastic agent 5-fluorouracil (5-FU) to enhance the cytotoxic effects of 5-FU. The combination has been shown to be superior to 5-FU alone in the treatment of patients with metastatic colorectal carcinoma. Methenyltetrahydrofolate synthetase (MTHFS) catalyzes the transformation of 5-formyltetrahydrofolate to methenylH(4)folate, which is the obligatory initial metabolic step prior to the intracellular conversion of 5-formylH(4)folate to other reduced folates and the increase in intracellular folate pools required for 5-FU potentiation. In the following paper, we will summarize results of biochemical and molecular studies of human MTHFS.