gebhart/patrepeval huggingface dataset:
Trifluoromethyl Ketone-Based Inhibitors of Apoptosis in Cerebellar Granule Neurons. (2001)

A variety of aromatic trifluoromethyl ketone derivatives has been studied as inhibitors of apoptosis in cerebellar granule neurons (CGNs). Among them, alpha-trifluoromethyl diketone (2) and benzyl trifluoromethyl ketone (11) were found to be apoptosis inhibitors which can prevent a neurodegenerative disease. Compounds 2 and 11 showed neuroprotection effect on low K+-induced apoptosis in CGNs. Furthermore, these compounds effectively suppressed DNA fragmentation accompanied with apoptosis. The neuroprotection mode of 2 and 11 was not related to inhibition of caspase-3.
Evaluation of treatment of late-onset tibia vara using gradual angulation translation high tibial osteotomy. (2010)

Late-onset tibia vara or Blount's disease is the most common cause of pathologic genu varum in children and adolescents. Treatment remains controversial. Many studies in the past have shown that an osteotomy with acute correction is the most appropriate treatment. More recently however, there has been a growing interest, especially in severe cases, in using gradual correction with the Ilizarov technique after a single high tibial osteotomy. A retrospective study in 20 children with late-onset tibia vara, who were treated by gradual angulation translation high tibial osteotomy using the Ilizarov technique, was performed. The mean follow-up period was 2.9 years (range: 2-4 years; SD 0.75). Recurrence of varus deformity to various degrees was noted in 10 of 22 cases (45.5%). Recurrence of deformity was found to be significantly related to both the degree of pre-operative deviation and the duration of follow-up. No statistically significant relationship was found between recurrence and the age of the patients at the time of the operation. Angulation translation high tibial osteotomy using the Ilizarov technique is a unique method for realignment of the mechanical axis in late onset tibia vara. It also allows for correction of associated deformities. The rate of recurrence of varus deformity is however relatively high.
Animal poxvirus vaccines: a comprehensive review (2012)

The family Poxviridae includes several viruses of medical and veterinary importance. Global concerted efforts combined with an intensive mass-vaccination campaign with highly efficaceious live vaccine of vaccinia virus have led to eradication of smallpox. However, orthopoxviruses affecting domestic animals continue to cause outbreaks in several endemic countries. Different kinds of vaccines starting from conventional inactivated/attenuated to recombinant protein-based vaccines have been used for control of poxvirus infections. Live virus homologous vaccines are currently in use for diseases including capripox, parapox, camelpox and fowlpox, and these vaccines are highly effective in eliciting (with the exception of parapoxviruses) long-lasting immunity. Attenuated strains of poxviruses have been exploited as vectored vaccines to deliver heterologous immunogens, many of them being licensed for use in animals. Worthy of note are vaccinia virus, fowlpox virus, capripoxvirus, parapoxvirus and canary pox, which have been successfully used for developing new-generation vaccines targeting many important pathogens. Remarkable features of these vaccines are thermostability and their ability to engender both cellular and humoral immune responses to the target pathogens. This article updates the important vaccines available for poxviruses of livestock and identifies some of the research gaps in the present context of poxvirus research.
Superconducting In-Vacuum Undulators (2006)

During the last years the Research Center Karlsruhe developed novel high-field superconducting in-vacuum undulators with period lengths of 3.8 and 14 mm. The undulators were tested with beam, both in linac type accelerators (Mainzer Microtron MAMI) and storage rings (ANKA). Based on this experience a new generation of superconducting undulators is planned: undulators capable of electrical field error compensation, undulators with electrically variable polarization direction and high brilliance for various accelerators
On Positive Harris Recurrence of Multiclass Queueing Networks: A Unified Approach Via Fluid Limit Models (1995)

It is now known that the usual traffic condition (the nominal load being less than 1 at each station) is not sufficient for stability for a multiclass open queueing network. Although there has been some progress in establishing the stability conditions for a multiclass network, there is no unified approach to this problem. In this paper, we prove that a queueing network is positive Harris recurrent if the corresponding fluid limit model eventually reaches zero and stays there regardless of the initial system configuration. As an application of the result, we prove that single class networks, multiclass feedforward networks and first-buffer-first-served preemptive resume discipline in a reentrant line are positive Harris recurrent under the usual traffic condition.
The performance study of axial breather with honeycomb in the aero-engine lubrication system (2015)

Axial breather is the important component to separate oil from oil-gas two-phase flow and reduce the consumption of lubricating oil circulation. This paper focused on the oil-gas separation efficiency of axial breather with honeycomb, and the mathematical model was established. ANSYS-Fluent was adopted for numerical computation, and the characteristics of oil-gas separation efficiency with droplet diameter and rotation speed were achieved. The results show that the axial breather with honeycomb designed here has favourable separation efficiency, which is estimated as 99.6% for an average oil droplet diameter of 5 mum, and the honeycomb structure plays a major role in the oil-gas separation of breather, where the amount of oil separation account for 80% of total amount of oil separation.
A multi-layered display with water drops (2010)

We present a multi-layered display that uses water drops as voxels. Water drops refract most incident light, making them excellent wide-angle lenses. Each 2D layer of our display can exhibit arbitrary visual content, creating a layered-depth (2.5D) display. Our system consists of a single projector-camera system and a set of linear drop generator manifolds that are tightly synchronized and controlled using a computer. Following the principles of fluid mechanics, we are able to accurately generate and control drops so that, at any time instant, no two drops occupy the same projector pixel's line-of-sight. This drop control is combined with an algorithm for space-time division of projector light rays. Our prototype system has up to four layers, with each layer consisting of an row of 50 drops that can be generated at up to 60 Hz. The effective resolution of the display is 50x projector vertical-resolution x number of layers. We show how this water drop display can be used for text, videos, and interactive games.
Window length effect on cross frequency coupling in an EEG processing circuit (2015)

This paper examines the window size selection used for measuring cross frequency coupling (CFC) in digitized electroencephalograph (EEG) signals. As with many signal processing algorithms, a larger time window results in more accurate and less noisy results but at the cost of a lower temporal resolution. In this paper, a range of window sizes (in samples per second) is examined using a synthetic test signal and, based on this analysis, the window size selection is made for a hardware implementation of the modulation index CFC algorithm. We found the optimized window length is 512 samples/second for EEG signals. An ASIC has been created from this design using the IBM 0.18 micron process with a chip size of 3mm × 3mm with 191mW power consumption and is currently being tested.
A simplified Horiuti‐Polanyi scheme for the hydrogenation of triacylglycerols (1991)

A simplification of the Horiuti‐Polanyi reaction scheme for the hydrogenation of triacylglycerols taking into account saturation and cis‐trans isomerization of double bonds and neglecting their positional isomerization is presented. From the comparison of experimental and calculated kinetic runs, the rate constants of individual reaction steps are obtained and the effects of hydrogen flow, hydrogen dispersion, oil unsaturation and catalyst quality on the rate constants are examined. Criteria for comprehensive characterization of the processes occurring in the course of hydrogenation, i.e., saturation and isomerization indices, are proposed.
Intramyocardial haemorrhage after acute myocardial infarction (2014)

In patients with acute myocardial infarction (AMI), the guideline-recommended treatment is mechanical revascularization by percutaneous coronary intervention (PCI), which is effective at reducing mortality. However, a substantial proportion of patients with AMI develop chronic cardiac failure owing to poor restoration of microvascular function and myocardial perfusion, despite restoration of epicardial vessel patency. This occurrence is called the 'no-reflow' phenomenon. Although pathological and clinical observations initially seemed to support the hypothesis that no-reflow was the result of microvascular obstruction, irreversible microvascular injury and subsequent intramyocardial haemorrhage are now also thought to be important factors in this process. Intramyocardial haemorrhage shares several pathophysiological features with the haemorrhagic transformation that occurs after ischaemic stroke. Understanding of the role of intramyocardial haemorrhage in the no-reflow phenomenon and myocardial injury is crucial to the development of new therapeutic strategies to treat AMI. In this Review, we provide a comprehensive overview of the pathogenesis and clinical relevance of intramyocardial haemorrhage, and discuss diagnostic options and future therapeutic strategies.
A hybrid scheme for low bit-rate coding of stereo images (2002)

In this paper, we propose a hybrid scheme to implement an object driven, block based algorithm to achieve low bit-rate compression of stereo image pairs. The algorithm effectively combines the simplicity and adaptability of the existing block based stereo image compression techniques with an edge/contour based object extraction technique to determine appropriate compression strategy for various areas of the right image. Unlike the existing object-based coding such as MPEG-4 developed in the video compression community, the proposed scheme does not require any additional shape coding. Instead, the arbitrary shape is reconstructed by the matching object inside the left frame, which has been encoded by standard JPEG algorithm and hence made available at the decoding end for those shapes in right frames. Yet the shape reconstruction for right objects incurs no distortion due to the unique correlation between left and right frames inside stereo image pairs and the nature of the proposed hybrid scheme. Extensive experiments carried out support that significant improvements of up to 20% in compression ratios are achieved by the proposed algorithm in comparison with the existing block-based technique, while the reconstructed image quality is maintained at a competitive level in terms of both PSNR values and visual inspections.
The living world (1994)

Designed for the younger reader, this series features details of the largest, the tiniest, the first, and so on, giving facts, descriptions and explanations of the phenomena illustrated. The Living World looks at animal records.
The Power of words: unveiling the speaker and writer's hidden craft (2004)

Contents: T. Oakley, Foreword. Preface. Introduction: Words and Their Potency for Priming Audiences. Part I:Preliminaries. Priming Audience and Practices of Literacy. Cataloging English Strings for Their Priming Potencies: A Report of a Research Study. Methods for Selecting and Catloging Strings. The Catalog Hierarchy. The Hierarchy in Relation to Previous Scholarship. Part II:Results: The Catalog in Depth. Cluster 1: Internal Perspectives. Cluster 2: Relational Perspectives, Part I. Cluster 2: Relational Perspectives, Part II. Cluster 3: External Perspectives. Part III:Implications and Applications of Rhetorical Priming Theory. Using Priming Strings to Analyze Corpora of Texts.
Secure friend discovery in mobile social networks (2011)

Mobile social networks extend social networks in the cyberspace into the real world by allowing mobile users to discover and interact with existing and potential friends who happen to be in their physical vicinity. Despite their promise to enable many exciting applications, serious security and privacy concerns have hindered wide adoption of these networks. To address these concerns, in this paper we develop novel techniques and protocols to compute social proximity between two users to discover potential friends, which is an essential task for mobile social networks.We make three major contributions. First, we identify a range of potential attacks against friend discovery by analyzing real traces. Second, we develop a novel solution for secure proximity estimation, which allows users to identify potential friends by computing social proximity in a privacy-preserving manner. A distinctive feature of our solution is that it provides both privacy and verifiability, which are frequently at odds in secure multiparty computation. Third, we demonstrate the feasibility and effectiveness of our approaches using real implementation on smartphones and show it is efficient in terms of both computation time and power consumption.
Stereoselective cyclization of (2-bromophenyl)- and (2-iodophenyl)alkynes catalyzed by palladium(O) complexes (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStereoselective cyclization of (2-bromophenyl)- and (2-iodophenyl)alkynes catalyzed by palladium(O) complexesRen Tzong Wang, Fan Lan Chou, and Fen Tair LuoCite this: J. Org. Chem. 1990, 55, 16, 4846–4849Publication Date (Print):August 1, 1990Publication History Published online1 May 2002Published inissue 1 August 1990https://pubs.acs.org/doi/10.1021/jo00303a017https://doi.org/10.1021/jo00303a017research-articleACS PublicationsRequest reuse permissionsArticle Views491Altmetric-Citations45LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Effect of Fly Ash particle size on its capacity to neutralize Acid Mine Drainage and influence on the rheological behaviour of residual solids (2007)

Abstract Fly Ash (FA) from South African power stations was successfully used to treat Acid Mine Drainage (AMD) and the insoluble residual solids that were obtained as a result of the reaction between FA and AMD proved suitable as a backfill material for mine stabilization. Particle Size Distribution (PSD) of FA varies from time to time depending on the coal burning conditions in the power station. Such variability in PSD of FA could influence its capability to neutralize AMD as well as the flow behaviour of residual solids that have to be transported hydraulically to the backfill site. The objective of this paper is to study the influence of variability of PSD on the above mentioned properties.
Paclitaxel combined with cis-platin as second-line treatment in patients with advanced non-small cell lung cancers refractory to cis-platin. (1999)

We combined paclitaxel with cis-platin as second-line treatment in patients with non-small cell lung cancer (NSCLC) who had previously undergone first-line therapy with cis-platin combined with cytotoxic drugs other than taxanes. The aim was to evaluate the effect of this cytotoxic combination in patients with refractory tumour to cis-platin. All 36 patients in the study population were evaluable for toxicity and 35 for response. Nine patients were stage IIIa, 15 IIIb and 12 IV. Prior treatment involved cis-platin plus vindesine and epirubicin or vinblastine and mitomycin-C; second-line treatment involved cis-platin (90 mg/m2) and paclitaxel (175 mg/m2), administered once every 3 weeks with 2-6 courses per patient. Partial response (40%) was obtained in 14 patients, 8 of whom had achieved minor response or stable disease after first-line treatment. Response duration was a minimum of 3 months. Toxicity was tolerable; only neurotoxicity was grade II in 16.7% of the patients. On the basis of our results, paclitaxel can be recommended as a very effective cytotoxic drug for NSCLC patients.
Convolutional Neural Networks to Enhance Coded Speech (2018)

Enhancing coded speech suffering from far-end acoustic background noise, quantization noise, and potentially transmission errors, is a challenging task. In this work we propose two postprocessing approaches applying convolutional neural networks (CNNs) either in the time domain or the cepstral domain to enhance the coded speech without any modification of the codecs. The time domain approach follows an end-to-end fashion, while the cepstral domain approach uses analysis-synthesis with cepstral domain features. The proposed postprocessors in both domains are evaluated for various narrowband and wideband speech codecs in a wide range of conditions. The proposed postprocessor improves speech quality (PESQ) by up to 0.25 MOS-LQO points for G.711, 0.30 points for G.726, 0.82 points for G.722, and 0.26 points for adaptive multirate wideband codec (AMR-WB). In a subjective CCR listening test, the proposed postprocessor on G.711-coded speech exceeds the speech quality of an ITU-T-standardized postfilter by 0.36 CMOS points, and obtains a clear preference of 1.77 CMOS points compared to legacy G.711, even better than uncoded speech with statistical significance. The source code for the cepstral domain approach to enhance G.711-coded speech is made available.
Polarisation mode dispersion measurements in long single mode fibres (1980)

A frequency domain determination of polarisation mode dispersion in single mode fibres is described, which allows one to obtain directly the group delay difference for long fibres. The results of such measurements are shown on a birefringent fibre with elliptical cross-section which maintains an extinction ratio between linearly polarised eigenstates greater than 10 dB over 1 km.
Power consumption reduction by multi-hop transmission in cellular networks (2005)

Multi-hop transmission breaks the single-hop path from a mobile station to the base station into two or more hops. In this case, distances between transmitters and receivers are smaller than that in the direct transmission case, hence it is expected that transmit power will be greatly reduced. In this paper, we analyze the probability that a mobile station can find its relay, and the average power consumption of mobile stations and their relays compared to the power consumption in case of direct transmission. As the number of relaying stations increases, it is highly probable that mobile stations can find their relay and save power. The gain of power saving through a two-hop relay is much greater when the path loss becomes greater.
Spatial-Temporal Fusion Graph Neural Networks for Traffic Flow Forecasting (2020)

Spatial-temporal data forecasting of traffic flow is a challenging task because of complicated spatial dependencies and dynamical trends of temporal pattern between different roads. Existing frameworks typically utilize given spatial adjacency graph and sophisticated mechanisms for modeling spatial and temporal correlations. However, limited representations of given spatial graph structure with incomplete adjacent connections may restrict effective spatial-temporal dependencies learning of those models. To overcome those limitations, our paper proposes Spatial-Temporal Fusion Graph Neural Networks (STFGNN) for traffic flow forecasting. SFTGNN could effectively learn hidden spatial-temporal dependencies by a novel fusion operation of various spatial and temporal graphs, which is generated by a data-driven method. Meanwhile, by integrating this fusion graph module and a novel gated convolution module into a unified layer, SFTGNN could handle long sequences. Experimental results on several public traffic datasets demonstrate that our method achieves state-of-the-art performance consistently than other baselines.
A next-generation beneficial microbe: <i>Akkermansia muciniphila</i> (2018)

There have been many reports on the roles of intestinal flora and intestinal environment in health promotion and disease prevention. Beneficial bacteria such as <i>Bifidobacterium</i> and lactic acid-producing bacteria have been shown to improve the intestinal environment, and yield a good effect on metabolism, immunity and nerve response. In this review, in addition to these beneficial bacteria, we introduced <i>Akkermansia muciniphila</i> as a next-generation beneficial microbe. Several reports indicate that <i>Akkermansia muciniphila</i> affects glucose metabolism, lipid metabolism, and intestinal immunity, and that certain food ingredients such as polyphenols may increase the abundance of <i>Akkermansia muciniphila</i> in the gut.
Current feedback opamp limitations: a state-of-the-art review (2002)

The current-feedback amplifier delivers large high-frequency signals linearly into heavy loads. It provides relatively constant bandwidth over a range of fed-back gains. Offsets, gain errors, and settling tails are prevalent in the design, and are investigated. Specific topics addressed include static DC errors, settling performance, frequency response aberrations, and noise characteristics.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Progesterone administration in patients with absent ovaries. (1989)

Forty-four women with absent ovaries who were referred to our centre for oocyte donation were treated with oestradiol valerate and natural progesterone. Serum concentrations and endometrial changes were evaluated on day 21 of stimulated luteal phases after the daily administration of 100 mg of natural progesterone in oil injected intramuscularly or after the ingestion of 300 mg of micronized progesterone or after vaginal administration of 300 mg or 600 mg micronized progesterone, respectively. Endometrial tissue did not show evidence of an adequate secretory pattern after orally administered progesterone. However, after intramuscular injection of 100 mg of natural progesterone and after the vaginal administration of 300 to 600 mg of micronized progesterone, the histologic and electron microscopic pictures were similar in all treatment groups and were close to the expected day 21 of the cycle. Serum levels of progesterone after intramuscular injection were five times higher than after vaginal administration.
[Gene expression of MMP1 and TIMP1 in lung cancer detected with a cDNA microarray technique]. (2003)

MMP1 and TIMP1 may be important molecular markers of squmas cell lung cancer and adenocarcinoma.