gebhart/patrepeval huggingface dataset:
Intellectual Property Protection in Collaborative Design through Lean Information Modeling and Sharing (2005)

Abstract Establishing efficient, effective, and trustworthy engineering collaboration while protecting intellectual property is vital to maintain organizational competence in today’s global business environment. In this paper, a lean information modeling and sharing framework is described to support engineering data security management in a peer-to-peer collaborative environment. It allows for selective and interoperable data sharing with fine-grained access control at both the server and client sides, thus securing different levels of design information dissemination for intellectual property protection purposes. The considerations of time and value-adding activity with roles, policy delegation relation in a distributed context, and fine-grained control at data set level in the model are to adhere to the general least privilege principle in access control. Heterogeneous design data are exchanged selectively through an eXtensible Markup Language common interface, which provides a neutral format to enhance data interoperability and prevents reverse engineering.
The First Solid-Phase Synthesis of a Peptide-Tethered Platinum(II) Complex (2000)

Assembly of an immobilized tripeptide, platination, and subsequent deprotection and release from the solid support are the key steps in the solid-phase peptide synthesis of the peptide–platinum(II) complex 1. This new methodology should be applicable for the preparation of a library of platinum antitumor compounds by a combinatorial synthesis approach.
Microwave Drying of Corn II. Constant Power, Continuous Operation (1992)

In the use of microwave energy for drying corn, drying rate increased with microwave power level but decreased with air velocity. The temperature of the kernels in the bed increased with increasing power as evidenced by the higher outlet air temperatures. Inlet air temperature did not affect the drying behavior. The moisture content of the corn at any given instant was higher for higher inlet air velocities. Germination was inversely related to microwave power level and increased with air velocity. Power levels not higher than 0.25 W/g are recommended for seed drying purposes. Predictive models relating absorbed microwave power and air velocity to germination and bulk density are presented.
Multiplex polymerase chain reaction for diagnosis of viral and chlamydial keratoconjunctivitis. (2000)

With clinical specimens the multiplex PCR was as sensitive as its respective uniplex PCRs but more sensitive than adenovirus isolation and as sensitive as herpes simplex virus isolation or C. trachomatis Amplicor PCR. It has the potential to replace several diagnostic tests with consequent savings in cost. The test also reduces the risk of misdiagnosis by the clinicians.
Techniques for effective distributed physical synthesis (2007)

We present two techniques, (1) placement-based timing-driven partitioner (PTP) and (2) virtual physical synthesis based budgeter (VSB), that support effective distributed physical synthesis.
Analysis of Real-World Data on Overall Survival in Multiple Myeloma Patients With ≥3 Prior Lines of Therapy Including a Proteasome Inhibitor (PI) and an Immunomodulatory Drug (IMiD), or Double Refractory to a PI and an IMiD (2016)

This real-world retrospective study of electronic health records examines the survival outcomes of patients with multiple myeloma who are heavily pretreated or highly refractory to currently approved treatments, including recently approved proteasome inhibitors and immunomodulatory drugs. This survival analysis showed that outcomes for these patients remain poor despite the availability of newer agents, with median overall survival of approximately 8 months. These findings highlight a critical need to develop novel therapies for these patients and also serve as a reference point against which emerging agents for heavily pretreated or highly refractory disease may be evaluated.
Optoacoustic brain stimulation at submillimeter spatial precision (2020)

Low-intensity ultrasound is an emerging modality for neuromodulation. Yet, transcranial neuromodulation using low-frequency piezo-based transducers offers poor spatial confinement of excitation volume, often bigger than a few millimeters in diameter. In addition, the bulky size limits their implementation in a wearable setting and prevents integration with other experimental modalities. Here, we report spatially confined optoacoustic neural stimulation through a miniaturized Fiber-Optoacoustic Converter (FOC). The FOC has a diameter of 600 μm and generates omnidirectional ultrasound wave locally at the fiber tip through the optoacoustic effect. We show that the acoustic wave generated by FOC can directly activate individual cultured neurons and generate intracellular Ca<sup>2+</sup> transients. The FOC activates neurons within a radius of 500 μm around the fiber tip, delivering superior spatial resolution over conventional piezo-based low-frequency transducers. Finally, we demonstrate direct and spatially confined neural stimulation of mouse brain and modulation of motor activity in vivo.
Risk of dengue virus infection according to serostatus in individuals from dengue endemic areas of Mexico (2020)

The variability in the host immune response directed against dengue virus (DENV) has demonstrated the need to understand the immune response associated with protection in incident infection. The objective was to estimate the association between serostatus and the risk of incident DENV infection. We used a prospective study from 2014 to 2016 in the localities of Axochiapan and Tepalcingo, Morelos, Mexico. We recruited 966 participants, of which, according to their infection history registered were categorized in four groups. To accomplish the objectives of this study, we selected to 400 participants older than 5 years of age were followed for 2.5 years. Blood samples were taken every 6 months to measure serological status and infection by ELISA. In individuals with at least two previous infections the risk of new infection was lower compared to a seronegative group (hazard ratio adjusted 0.49, 95% CI 0.24-0.98), adjusted for age and locality. Therefore, individuals who have been exposed two times or more to a DENV infection have a lower risk of re-infection, thus showing the role of cross-immunity and its association with protection.
A GENERAL CLASS OF ESTIMATORS OF A FINITE POPULATION MEAN USING MULTI-AUXILIARY INFORMATION UNDER TWO STAGE DOUBLE SAMPLING SCHEME (2009)

When the population mean X of the auxiliary variate x is not known, it is well known that two-phase sampling is of significant use in practice. Keeping this in view, a general class of estimators is suggested to estimate the population mean for the variable under study using auxiliary variable in two stage double sampling scheme. Some special cases of this class of estimators are considered and compared by using a data set. Finally, it is shown, how to extend the class of estimators if multi auxiliary variables are available in the case of two stage double sampling scheme. The approximate expressions for bias and mean square error of the suggested estimators have also been derived and theoretical results are numerically supported.
Homogeneously Alloyed CdS<i><sub>x</sub></i>Se<sub>1</sub><sub>-</sub><i><sub>x</sub></i> Nanocrystals:  Synthesis, Characterization, and Composition/Size-Dependent Band Gap (2006)

Alloy nanocrystals provide an additional degree of freedom in selecting desirable properties for nanoscale engineering because their physical and optical properties depend on both size and composition. We report the pyrolytic synthesis of homogeneously alloyed CdSxSe1-x nanocrystals in all proportions. The nanocrystals are characterized using UV−visible absorption spectroscopy, transmission electron microscopy, X-ray diffractrometry, and Rutherford backscattering spectrometry to determine precisely structure, size, and composition. The dependence of band gap on nanocrystal size and composition is elucidated, yielding a bowing constant of 0.29, in agreement with bulk values. In addition, the morphology of the resultant nanocrystals can be altered by changing the reaction conditions, generating structures ranging from homogeneous, spherical nanocrystals to one-dimensional gradient nanorods.
Novel cost-efficient contactless distributed monitoring concept for smart battery cells (2012)

The market breakthrough of electric vehicles is mainly delayed by the still too high costs of the battery system. The novel distributed battery cell monitoring and management concept presented in this paper allows a significant reduction of the final battery pack costs. Further, due to economies of scale, it provides reduced development costs and much lower time-to-market. The proposed concept provides a contactless cost-efficient data transmission interface with capacitive coupling, thus making the development of a battery monitoring circuit for each battery module type needless. The costs are mainly reduced thanks to the high volume manufacturing approach of novel smart battery cells integrating all the sensors of the monitoring electronics together with passive cell balancing and cell heating function. This paper describes the possibilities offered by the proposed concept and shows implementation examples of such a contactless distributed battery cell monitoring.
MRI contrast agent for targeting glioma: interleukin-13 labeled liposome encapsulating gadolinium-DTPA (2015)

IL-13-liposome-Gd-DTPA is able to pass through the uncompromised BBB and detect an early stage glioma that cannot be seen with conventional contrast-enhanced MRI.
Testosterone inhibits estrogen‐induced mammary epithelial proliferation and suppresses estrogen receptor expression (2000)

This study investigated the effect of sex steroids and tamoxifen on primate mammary epithelial proliferation and steroid receptor gene expression. Ovariectomized rhesus monkeys were treated with placebo, 17beta estradiol (E2) alone or in combination with progesterone (E2/P) or testosterone (E2/T), or tamoxifen for 3 days. E2 alone increased mammary epithelial proliferation by approximately sixfold (P:<0.0001) and increased mammary epithelial estrogen receptor (ERalpha) mRNA expression by approximately 50% (P:<0.0001; ERbeta mRNA was not detected in the primate mammary gland). Progesterone did not alter E2's proliferative effects, but testosterone reduced E2-induced proliferation by approximately 40% (P:<0.002) and entirely abolished E2-induced augmentation of ERalpha expression. Tamoxifen had a significant agonist effect in the ovariectomized monkey, producing a approximately threefold increase in mammary epithelial proliferation (P:<0.01), but tamoxifen also reduced ERalpha expression below placebo level. Androgen receptor (AR) mRNA was detected in mammary epithelium by in situ hybridization. AR mRNA levels were not altered by E2 alone but were significantly reduced by E2/T and tamoxifen treatment. Because combined E2/T and tamoxifen had similar effects on mammary epithelium, we investigated the regulation of known sex steroid-responsive mRNAs in the primate mammary epithelium. E2 alone had no effect on apolipoprotein D (ApoD) or IGF binding protein 5 (IGFBP5) expression, but E2/T and tamoxifen treatment groups both demonstrated identical alterations in these mRNAs (ApoD was decreased and IGFBP5 was increased). These observations showing androgen-induced down-regulation of mammary epithelial proliferation and ER expression suggest that combined estrogen/androgen hormone replacement therapy might reduce the risk of breast cancer associated with estrogen replacement. In addition, these novel findings on tamoxifen's androgen-like effects on primate mammary epithelial sex steroid receptor expression suggest that tamoxifen's protective action on mammary gland may involve androgenic effects.
Atomic Layer Deposition of Nickel Nitride Thin Films using NiCl<sub>2</sub>(TMPDA) and Tert‐Butylhydrazine as Precursors (2019)

This article describes the atomic layer deposition (ALD) of nickel nitride and nickel thin films using a diamine adduct of Ni(II) chloride, NiCl 2 (TMPDA) (TMPDA = N,N,N′,N′, ‐tetramethyl‐1,3‐propanediamine), as the metal precursor. Owing to the high reducing power of tert‐butylhydrazine (TBH), the films are grown at low temperatures of 190–250 °C. This is one of the few low‐temperature ALD processes that can be used to grow Ni 3 N and Ni metal on both insulating and conductive substrates. The films are characterized in terms of crystallinity, morphology, composition, resistivity, and coercivity. X‐ray diffraction shows reflections compatible with either hexagonal Ni or Ni 3 N. Composition analyses suggest that the films are close to stoichiometric Ni 3 N. Despite the nitride component, the films exhibit low resistivity values and at the lowest, a resistivity of 37 μΩ cm is achieved. The result is lower than what is typically observed for Ni x N films and not much higher than the best results concerning ALD Ni metal. The nitrogen content of the films is lowered down to 1.2 at% by postdeposition reduction at 150 °C in 10% forming gas. After the reduction, the nonmagnetic nitride films are converted to ferromagnetic Ni metal.
Electrostrictive microelectromechanical fibres and textiles (2017)

Microelectromechanical systems (MEMS) enable many modern-day technologies, including actuators, motion sensors, drug delivery systems, projection displays, etc. Currently, MEMS fabrication techniques are primarily based on silicon micromachining processes, resulting in rigid and low aspect ratio structures. In this study, we report on the discovery of MEMS functionality in fibres, thereby opening a path towards flexible, high-aspect ratio, and textile MEMS. The method used for generating these MEMS fibres leverages a preform-to-fibre thermal drawing process, in which the MEMS architecture and materials are embedded into a preform and drawn into kilometers of microstructured multimaterial fibre devices. The fibre MEMS functionality is enabled by an electrostrictive P(VDF-TrFE-CFE) ferrorelaxor terpolymer layer running the entire length of the fibre. Several modes of operation are investigated, including thickness-mode actuation with over 8% strain at 25 MV m<sup>-1</sup>, bending-mode actuation due to asymmetric positioning of the electrostrictive layer, and resonant fibre vibration modes tunable under AC-driving conditions.
Role of <i>N</i>-Acyl Amino Acid Ligands in Pd(II)-Catalyzed Remote C–H Activation of Tethered Arenes (2013)

A combined experimental/computational study on the amino acid ligand-assisted Pd-catalyzed C-H bond activation reveals a mechanism in which the amino acid acts as both a dianionic bidentate ligand and a proton acceptor. This new model explains the effects of amino acids on reactivity and selectivity and unveils the dual roles of amino acids: stabilizing monomeric Pd complexes and serving as the internal base for proton abstraction.
Properties of Milk Protein Gels Formed by Phosphates (2007)

We investigated the properties of gels that were formed by adding emulsifying salts, such as tetrasodium pyrophosphate (TSPP), to reconstituted milk protein concentrate solution. The pH of a 51 g/L milk protein concentrate solution was adjusted to 5.8 after adding TSPP. Milk protein concentrate solutions were placed in glass jars and allowed to stand at 25 degrees C for 24 h. Gels with the highest breaking force were formed when TSPP was added at a concentration of 6.7 mM, whereas no gel was formed when TSPP was added at concentrations of < or =2.9 or > or =10.5 mM. Several other phosphate-based emulsifying salts were tested but for these emulsifying salts, gelation only occurred after several days or at greater gelation temperatures. No gelation was observed for trisodium citrate. Gelation induced by TSPP was dependent on pH, and the breaking force of gel was greatest at pH 6.0. Furthermore, when the concentration of milk protein concentrate in solution was increased to 103 g/L, the breaking force of the gel increased, and a clearly defined network between caseins could be observed by using confocal scanning laser microscopy. These results suggest that TSPP-induced gelation occurs when the added TSPP acts with calcium as a cross-linking agent between dispersed caseins and when the balance between (a reduced) electrostatic repulsion and (enhanced) attractive (hydrophobic) interactions becomes suitable for aggregation and eventual gelation of casein molecules.
[Clinico-hemodynamic characteristics of patients with initial signs of hypertension]. (1991)

Multifactor analysis was used to make clinical and hemodynamic comparisons in 42 patients with borderline arterial hypertension, 27 with Stage I hypertension, 40 with Stage II hypertension, and 40 healthy persons. Central hemodynamic parameters at rest and during graded bicycle ergometer exercise were measured by the Defares carbon dioxide return respiration method modified by V. L. Karpman. As compared with patients with hyperkinetic circulation, those with hypokinetic one were older, had a longer history of arterial hypertension, obesity, more common left ventricular hypertrophy, higher baseline diastolic pressures and total peripheral vascular resistance, less increase in cardiac index and greater enhancement of total peripheral vascular resistance during submaximal exercise. There was a clear-cut correlation between the progression of arterial hypertension and increase in values of factors I (clinical and hemodynamic) and III (cardiotonic).
Embryoide Differenzierungsmuster im Kallus der Gattungen <i>Iris</i> und <i>Asparagus</i> (1977)

Zusammenfassung

Die verschiedenen Differenzierungsmuster im Kallus der Gattungen Iris und Asparagus wurden histologisch untersucht. Es konnte im Kallus aus explantierten Sprosscheiteln von Iris-Sektionshybriden auf einem Medium nach Linsmaier/skoog (L/S) mit 2,4-D-Zusatz die Entstehung einer grosen Zahl nichtzygotischer Embryoide nachgewiesen werden. Die bipolare Struktur entwickelte sich verhaltnismasig spat aus kleinzelligen, rundlichen oder langlichen Arealen, die sich mit einem Protoderm allmahlich gegen den ubrigen Kallus abgrenzten. Nach Abschlus der embryoiden Organisation wiesen die kallusburtigen Embryonen das typische Strukturmuster eines monokotylen Embryos auf und keimten wie zygotische Embryonen ohne Zusatz von Wachstums-regulatoren auf nahrstoffarmen Medien.



Aus Sprossegmenten von xx-, xy- und yy-Stammen von Asparagus officinalis wurde auf L/S durch Zusatz von NES und Kinetin ein uppiger Kallus induziert. Auf IES - und BAP-haltigen Medien im Verhaltnis 1: 1 oder 10: 1 haben sich neben Sprossen und Wurzeln auch embryoide Formen entwickelt. Die Sprosanlagen entstanden einzeln oder in Dreiergruppen am Kallusrand, die Wurzelanlagen wurden im Innern des Kallusgewebes aufgefunden. Der embryogene Charakter globularer Formen, bestehend aus plasmareichen Zellen im peripheren Kallusbereich, wurde beschrieben. Bipolare Gebilde mit Spros-und Wurzelpol, Prokambiumstrang und Kotyledoanlage wichen mehr oder weniger stark vom Bau zygotischer Embryonen ab. In der Weiterkultur auf wuchsstoffarmen Medien keimten diese Embryoide wie zygotische Embryonen. Die Mehrzahl der in Buscheln aus alteren Kalluskulturen herauswachsenden 3 bis 4 mm grosen und auserlich von Embryoiden nicht zu unterscheidenden weisen Gebilde sind hypertrophierte Phyllocladienhomologe. Sie gehoren entweder zu einem breiten Scheitelmeristem und stellen somit einen aberranten Vegetationskegel dar oder sie verwachsen unter Aussparung eines zentralen Hohlraumes. In dieser Hohle mit einer basalen Offnung befinden sich ein bis drei normal strukturierte Sprosknospen.
Infectious Diseases 1979--"Go West (or East) Young Man (or Woman)!" (1979)

Journal Article Infectious Diseases 1979—“Go West (or East) Young Man (or Woman)!” Get access Ian Gust Ian Gust member of the International Board of Editors Virus Laboratory Fairfield Hospital for Communicable DiseasesFairfield, Victoria, Australia Search for other works by this author on: Oxford Academic PubMed Google Scholar The Journal of Infectious Diseases, Volume 140, Issue 3, September 1979, Pages 423–425, https://doi.org/10.1093/infdis/140.3.423 Published: 01 September 1979
Miniaturization of Microstrip Patch Antennas for Gps Applications (2023)

The desire to incorporate multiple frequency bands of operation into personal communication devices has led to much research on reducing the size of antennas while maintaining adequate performance. GPS is one such application, where dual frequency operation, bandwidth and circular polarization pose major challenges when using traditional miniaturization techniques. Various loading methods have been studied to reduce the resonant frequency of the antenna – high permittivity dielectric loading, slot loading and cavity loading – while examining their effects on bandwidth and gain. The objective of this thesis is to provide guidelines on what is achievable using these miniaturization methods and insight into how to implement them effectively.
Neural Network Method To Analyze Data Compression in DNA and RNA Sequences (1997)

Neural network computations on RNA sequences are used to demonstrate that data compression is possible in these sequences. The result implies that a certain discrimination should be achievable between structured vs random regions. The technique is illustrated by computing the compressibility of short RNA sequences such as tRNA. The method should be valuable in measuring the information content of DNA, including noncoding DNA, which has been shown to display certain properties resembling natural language attributes.
Design methodologies for securing cyber-physical systems (2015)

Cyber-Physical Systems (CPS) are in most cases safety- and mission-critical. Standard design techniques used for securing embedded systems are not suitable for CPS due to the restricted computation and communication budget available in the latter. In addition, the sensitivity of sensed data and the presence of actuation components further increase the security requirements of CPS. To address these issues, it is necessary to provide new design methods in which security is considered from the beginning of the whole design flow and addressed in a holistic way. In this paper, we focus on the design of secure CPS as part of the complete CPS design process, and provide insights into new requirements on platform-aware design of control components, design methodologies and architectures posed by CPS design. We start by discussing methods for the multi-disciplinary modeling, simulation, tools, and software synthesis challenges for CPS. We also present a framework for design of secure control systems for CPS, while taking into account properties of the underlying computation and communication platforms. Finally, we describe the security challenges in the computing hardware that is used in CPS.
Location identification of high impedance faults using synchronized harmonic phasors (2017)

This paper proposes a novel method to identify the location of a high-impedance fault (HIF) in a power distribution system. The developed method uses synchronized harmonic phasors with focus on the third harmonic component. Such harmonic synchrophasors could be provided in practice, e.g., by distribution level phasor measurement units, a.k.a, μPMUs. In this regard, the location of the fault can be estimated based on the impedance that is calculated from the third harmonic voltage and current synchrophasors produced by the fault and captured by the μPMUs. In this method, both resistance and inductance are estimated, to allow fault location identification even in a network with multiple type conductors. Note that, the fault does not need to be fully observable. As few as two μPMUs would be sufficient to estimate the HIF location at least to certain accuracy. The effectiveness of the proposed method is demonstrated through simulating the IEEE 33 bus test system in PSCAD.