gebhart/patrepeval huggingface dataset:
El deporte en la UCLM: ocio y competición (1995)

Recognizing the importance of health-promoting relationships in engaging people who are experiencing homelessness in care, most research on health clinics for homeless persons has involved some recognition of client-provider relationships. However, what has been lacking is the inclusion of a critical analysis of the policy context in which relationships are enacted. In this paper, we question how client-provider relationships are enacted within the culture of community care with people who are experiencing homelessness and how clinic-level and broader social and health policies shape relationships in this context. We explore these questions within a critical theoretical perspective utilizing a critical ethnographic methodology. Data were collected using multiple methods of document review, participant observation, in-depth interviews and focus groups. The participants include both clients at a community health clinic, and all clinic service providers. We explore how clients and providers characterized each other as 'good' or 'bad'. For providers, this served as a means by which they policed behaviours and enforced social norms. The means by which both providers' and clients' negotiated relationships are explored, but this is couched within both local and system-level policies. This study highlights the importance of healthcare providers and clients being involved in broader policy and systemic change.
Tunable Fabry-Perot Filters (1981)

The Fabry-Perot interferometer is being applied increasingly as a tunable filter. The theoretical limits to its performance are considered, including the effects of phase change at multilayer reflecting coatings. Various forms of construction are discussed as are several ways of tuning Fabry-Perot filters. The review concludes with a description of a number of practical devices.
Expression of Neural Markers by Undifferentiated Rat Mesenchymal Stem Cells (2012)

The spontaneous expression of neural markers by mesenchymal stem cells (MSCs) has been considered to be a demonstration of MSCs' predisposition to differentiate towards neural lineages. In view of their application in cell therapy for neurodegenerative diseases, it is very important to deepen the knowledge about this distinctive biological property of MSCs. In this study, we evaluated the expression of neuronal and glial markers in undifferentiated rat MSCs (rMSCs) at different culture passages (from early to late). rMSCs spontaneously expressed neural markers depending on culture passage, and they were coexpressed or not with the neural progenitor marker nestin. In contrast, the number of rMSCs expressing mesengenic differentiation markers was very low or even completely absent. Moreover, rMSCs at late culture passages were not senescent cells and maintained the MSC immunophenotype. However, their differentiation capabilities were altered. In conclusion, our results support the concept of MSCs as multidifferentiated cells and suggest the existence of immature and mature neurally fated rMSC subpopulations. A possible correlation between specific MSC subpopulations and specific neural lineages could optimize the use of MSCs in cell transplantation therapy for the treatment of neurological diseases.
Historical Overfishing and the Recent Collapse of Coastal Ecosystems (2001)

Ecological extinction caused by overfishing precedes all other pervasive human disturbance to coastal ecosystems, including pollution, degradation of water quality, and anthropogenic climate change. Historical abundances of large consumer species were fantastically large in comparison with recent observations. Paleoecological, archaeological, and historical data show that time lags of decades to centuries occurred between the onset of overfishing and consequent changes in ecological communities, because unfished species of similar trophic level assumed the ecological roles of overfished species until they too were overfished or died of epidemic diseases related to overcrowding. Retrospective data not only help to clarify underlying causes and rates of ecological change, but they also demonstrate achievable goals for restoration and management of coastal ecosystems that could not even be contemplated based on the limited perspective of recent observations alone.
Global Economic Impact of Dental Diseases (2015)

Reporting the economic burden of oral diseases is important to evaluate the societal relevance of preventing and addressing oral diseases. In addition to treatment costs, there are indirect costs to consider, mainly in terms of productivity losses due to absenteeism from work. The purpose of the present study was to estimate the direct and indirect costs of dental diseases worldwide to approximate the global economic impact. Estimation of direct treatment costs was based on a systematic approach. For estimation of indirect costs, an approach suggested by the World Health Organization's Commission on Macroeconomics and Health was employed, which factored in 2010 values of gross domestic product per capita as provided by the International Monetary Fund and oral burden of disease estimates from the 2010 Global Burden of Disease Study. Direct treatment costs due to dental diseases worldwide were estimated at US$298 billion yearly, corresponding to an average of 4.6% of global health expenditure. Indirect costs due to dental diseases worldwide amounted to US$144 billion yearly, corresponding to economic losses within the range of the 10 most frequent global causes of death. Within the limitations of currently available data sources and methodologies, these findings suggest that the global economic impact of dental diseases amounted to US$442 billion in 2010. Improvements in population oral health may imply substantial economic benefits not only in terms of reduced treatment costs but also because of fewer productivity losses in the labor market.
System analysis and energy model for radio-triggered battery-less monolithic wireless sensor receiver (2013)

Monolithic wireless sensors with integrated antenna, on-chip transceiving, sensing and energy scavenging are low-cost and robust, thus very suitable for mass production and deployment. The design of such a sensor node requires a proper architecture with careful trade-offs and joint considerations over different building blocks. In this paper, we focus on the energy scavenging and receiver part of such a sensor node. A radio-triggered receiver architecture is proposed to achieve the extreme low energy budget. Energy/power models for different building blocks are developed that show the tradeoffs between available energy and sensor performance. A system-level analysis identifies the 60GHz mm-wave band is suitable for such applications. Moreover, a design example of receiver front-end in 65nm CMOS technology is presented to demonstrate the potential performance of the proposed architecture.
An adaptive algorithm of contour interpolation based on grid DEM (2003)

Grid based Digital Elevation Model(DEM) surface by bicubic spline was created, and an adaptive algorithm for computing contour from DEM was provided. Piecewise parametric cubic curve was used in the adaptive algorithm. In order to solve the contour function simply, the range of parameters by test was studied. The contour is secondorder continuous piecewise cubic but not a linear function, and a storage structure of contour information was also studied. The results show that the method can save 60%70% in storage than that of the tradition method and is particularly appropriate to geosciences application and analysis based on contour map.
Antigenic Variation of Envelope and Internal Proteins of Mumps Virus Strains Detected with Monoclonal Antibodies (1986)

Antigenic characteristics of nine mumps virus strains were determined by immunofluorescence and radioimmunoprecipitation assay (RIPA) using a collection of 44 monoclonal antibodies. These antibodies were directed against five different structural components of mumps virus, the haemagglutinin-neuraminidase (HN), fusion (F), matrix (M), phospho- (P) and nucleocapsid (NP) proteins. The nine mumps virus strains could be divided into two groups according to their antigenic characteristics. One group included two strains isolated more than a decade ago and the Jeryl Lynn vaccine strain. These three strains reacted with a wider range of monoclonal antibodies than the second group of six recently isolated strains of different geographical origin. In the F, M and P proteins variations were only found in single antigenic determinants. In the HN and NP components, RIPA revealed variations in three and seven determinants respectively. The Jeryl Lynn vaccine strain showed a unique lack of reaction with one anti-HN antibody clone in the RIPA.
Interactions between gut inflammation and arthritis/spondylitis (2010)

Human genome studies combined with animal model research provide us with new evidence in the fascinating field of the gut-joint axis. However, how these newly identified genetic associations can influence the immunological environment remains to be elucidated.
Two Cytokinin Receptors of Arabidopsis thaliana, CRE1/AHK4 and AHK3, Differ in their Ligand Specificity in a Bacterial Assay (2004)

Strains of Escherichia coli that express two different cytokinin receptors of Arabidopsis thaliana, CRE1/AHK4 and AHK3, were used to study the relative sensitivity of these receptors to various cytokinins. Both receptors were most sensitive to the bases of the isoprenoid-type cytokinins trans-zeatin and isopentenyladenine but differed significantly in the recognition of other cytokinin compounds. In particular, CRE1/AHK4 recognized at 1 microm concentration only trans-zeatin while AHK3 recognized cis-zeatin and dihydrozeatin as well, although with a lower sensitivity. Similarly, CRE1/AHK4 was not activated by cytokinin ribosides and ribotides, but AHK3 was. Comparisons using the ARR5::GUS fusion gene as a cytokinin reporter in Arabidopsis showed similar relative degrees of responses in planta, except that cytokinins with aromatic side chains showed much higher activities than in the bacterial assay. These results indicate that the diverse cytokinin compounds might have specific functions in the numerous cytokinin-regulated processes, which may depend in turn on different receptors and their associated signalling pathways. The importance of precise control of local concentrations of defined cytokinin metabolites to regulate the respective downstream event is corroborated.
LES CONDITIONS DE L’ATTRACTIVITÉ DES TERRITOIRES (2015)

International audience
Quantitative Pilomotor Axon Reflex Test (2012)

Phenylephrine provoked piloerection directly and indirectly through an axon reflex–mediated response that is attenuated by lidocaine. Piloerection is not stimulated by iontophoresis of normal saline alone.The quantitative pilomotor axon reflex test (QPART) may complement other measures of cutaneous autonomic nerve fiber function.
A List of the Butterflies (Lepidoptera: Papilionoidea) of the La Rue-Pine Hills Ecological Area (2017)

A survey of the adult butterfly fauna of the La Rue-Pine Hills Ecological Area, Union County, Illinois, was conducted from March through July in 1979, and March through November in 1980. Forty nine species and subspecies were collected including all six papilionids known to occur in Illinois. Notes were taken on seasonal flight periods and butterfly-plant associations.
A review of simulation optimization techniques (2002)

We present a review of methods for optimizing stochastic systems using simulation. The focus is on gradient based techniques for optimization with respect to continuous decision parameters and on random search methods for optimization with respect to discrete decision parameters.
Cyclooxygenase-2 and matrix metalloproteinase-9 expressions correlate with tissue inflammation degree in periodontal disease. (2015)

The presence of an intensive inflammatory infiltrate is characteristic both for periodontitis and gingivitis. MMP-9 and Cox-2 show higher expression in periodontitis, than in gingivitis and healthy controls, but MMP-9 and Cox-2 expression scores cannot be directly correlated to the grade of inflammatory infiltrate in the two different disease entities. As biomarkers of chronic inflammation activity, angiogenesis, and degradation of the extracellular matrix, MMP-9 and Cox-2 can be used in clinical practice for the detection of patients with chronic periodontitis risk, at whom treatment with Cox-2 and MMP-9 inhibitors may be considered.
Microstructure and Superplasticity in Various Zirconia-Dispersed Aluminas. (2002)

The differences in the kinds of zirconias used for dispersion, and the distribution of the zirconia particles both had an influence on the microstructure and the tensile ductility of the zirconia dispersed alumina. Every zirconia particle inhibited alumina from grain growth controlled by the Zener pinning model and zirconia grain growth rate. The pinning effect of each zirconia particle was different, because it could be dependent on the distribution of zirconia particles in the alumina. Finely and homogeneously the ZR-3Y particles dispersed in the alumina were quite effective in improving the microstructure and tensile ductility due to a suppression of the alumina grain growth.
Premature replacement of μ with α immunoglobulin chains impairs lymphopoiesis and mucosal homing but promotes plasma cell maturation (2010)

Sequentially along B cell differentiation, the different classes of membrane Ig heavy chains associate with the Ig alpha/Ig beta heterodimer within the B cell receptor (BCR). Whether each Ig class conveys specific signals adapted to the corresponding differentiation stage remains debated. We investigated the impact of the forced expression of an IgA-class receptor throughout murine B cell differentiation by knocking in the human C alpha Ig gene in place of the S mu region. Despite expression of a functional BCR, homozygous mutant mice showed a partial developmental blockade at the pro-B/pre-BI and large pre-BII cell stages, with decreased numbers of small pre-BII cells. Beyond this stage, peripheral B cell compartments of reduced size developed and allowed specific antibody responses, whereas mature cells showed constitutive activation and a strong commitment to plasma cell differentiation. Secreted IgA correctly assembled into polymers, associated with the murine J chain, and was transported into secretions. In heterozygous mutants, cells expressing the IgA allele competed poorly with those expressing IgM from the wild-type allele and were almost undetectable among peripheral B lymphocytes, notably in gut-associated lymphoid tissues. Our data indicate that the IgM BCR is more efficient in driving early B cell education and in mucosal site targeting, whereas the IgA BCR appears particularly suited to promoting activation and differentiation of effector plasma cells.
ENCAPSULATION OF LEU-ENKEPHALIN IN CORE-SHELL ISOBUTYLCYANOACRYLATE - THIOLATED CHITOSAN NANOPARTICLES FOR ORAL ADMINISTRATION (2008)

The present study shows the evaluation of Leu-Enkephalin (Leu-Enk) encapsulation on core-shell isobutylcyanoacrylate/thiolated chitosan (IBCA/ChitoTBA) nanoparticles as a tool of combined system of polymers and colloidal particles for oral administration of poor absorption drugs. Leu-Enk encapsulation using anionic emulsion polymerization technique was carried out previous depolymerization of MW 400,000 g . mol -1 commercial chitosan, followed by thiolation of this depolymerized chitosan with Traut's reagent (2-iminothiolane), and final characterization. Later, direct quantification of the encapsulated Leu-Enk into the nanoparticles was carried out evaluating two methodologies for nanoparticles rupture solubilization with: NaOH 1 N and DMSO. Physico-chemical characterization of the obtained nanoparticles showed diameters in the nano-range between 28 and 46 nm, and yields of encapsulation of Leu-Enk between 25 and 46%, and recovery yields over 96% for co-polymer nanoparticles solubilization method with DMSO.
PRN473, an inhibitor of Bruton's tyrosine kinase, inhibits neutrophil recruitment <i>via</i> inhibition of macrophage antigen‐1 signalling (2017)

PRN473, a highly selective inhibitor of Btk, potently attenuates sterile liver injury by inhibiting the activation of the β<sub>2</sub> -integrin Mac-1 and subsequently neutrophil recruitment into inflamed tissue.
Per-Pixel Displacement Mapping with Distance Functions (2005)

In this chapter, we present distance mapping, a technique for adding small-scale dis-placement mapping to objects in a pixel shader. We treat displacement mapping as a ray-tracing problem, beginning with texture coordinates on the base surface and calcu-lating texture coordinates where the viewing ray intersects the displaced surface. For this purpose, we precompute a three-dimensional distance map, which gives a measure of the distance between points in space and the displaced surface. This distance map gives us all the information necessary to quickly intersect a ray with the surface. Our algorithm significantly increases the perceived geometric complexity of a scene while maintaining real-time performance. Cook (1984) introduced displacement mapping as a method for adding small-scale detail to surfaces. Unlike bump mapping, which affects only the shading of surfaces, displacement mapping adjusts the positions of surface elements. This leads to effects not possible with bump mapping, such as surface features that occlude each other and
Synthesis of ultrafine layered double hydroxide (LDHs) nanoplates using a continuous-flow hydrothermal reactor (2012)

We report a novel continuous-flow hydrothermal method for the synthesis of layered double hydroxide (LDH) nanoplates. The precursor solutions may be fed to the reactor so that the production of LDHs occurs in a continuous mode. By control of the synthesis temperature, pressure and contact time, the synthesis of LDH nanoplates can be tuned with constant and consistent product quality. This very general and simple approach shows high potential for commercial scale-up.
Enhanced characterization of singly protonated phosphopeptide ions by femtosecond laser-induced ionization/dissociation tandem mass spectrometry (fs-LID-MS/MS) (2010)

To develop an improved understanding of the regulatory role that post-translational modifications (PTMs) involving phosphorylation play in the maintenance of normal cellular function, tandem mass spectrometry (MS/MS) strategies coupled with ion activation techniques such as collision-induced dissociation (CID) and electron-transfer dissociation (ETD) are typically employed to identify the presence and site-specific locations of the phosphate moieties within a given phosphoprotein of interest. However, the ability of these techniques to obtain sufficient structural information for unambiguous phosphopeptide identification and characterization is highly dependent on the ion activation method employed and the properties of the precursor ion that is subjected to dissociation. Herein, we describe the application of a recently developed alternative ion activation technique for phosphopeptide analysis, termed femtosecond laser-induced ionization/dissociation (fs-LID). In contrast to CID and ETD, fs-LID is shown to be particularly suited to the analysis of singly protonated phosphopeptide ions, yielding a wide range of product ions including a, b, c, x, y, and z sequence ions, as well as ions that are potentially diagnostic of the positions of phosphorylation (e.g., 'a(n)+1-98'). Importantly, the lack of phosphate moiety losses or phosphate group 'scrambling' provides unambiguous information for sequence identification and phosphorylation site characterization. Therefore, fs-LID-MS/MS can serve as a complementary technique to established methodologies for phosphoproteomic analysis.
<tt>RePS: </tt>A Sequence Assembler That Masks Exact Repeats Identified from the Shotgun Data (2002)

We describe a sequence assembler, RePS (repeat-masked Phrap with scaffolding), that explicitly identifies exact 20mer repeats from the shotgun data and removes them prior to the assembly. The established software is used to compute meaningful error probabilities for each base. Clone-end-pairing information is used to construct scaffolds that order and orient the contigs. We show with real data for human and rice that reasonable assemblies are possible even at coverages of only 4x to 6x, despite having up to 42.2% in exact repeats.
Study on APP Design of Idle Furniture Based on Service Design (2022)

The recycling and reuse of resources is an important way for sustainable development. Through the construction of the service system model, starting from the pain points of the user's perspective, a solution is proposed for the transaction and processing of idle furniture. This paper uses questionnaire surveys and other methods to collect user information, build user portraits, and build a prototype of the idle furniture transaction APP design. The user-centered idle furniture transaction service design combines the analysis of user emotions, pain points and opportunities to provide users with a more expected idle furniture transaction method, and promote the green and sustainable development of the furniture industry.
Combining high-resolution X-ray diffractometry and topography (1991)

Multiple-crystal diffraction profiles and multiple-crystal topography have been combined to characterize semiconductor materials. X-ray topographs have been measured on the same region of the sample as the diffraction profiles and diffraction space maps, by insetting a film cassette in the diffracted beam path of a high-resolution diffractometer. This has proved to be a very powerful combination for providing a deeper understanding of the structural features that give rise to the high-resolution diffraction profiles. The data collection mode is discussed and the problems associated with interpreting `rocking curves' of imperfect materials. The misorientation and nature of the mosaic blocks in semi-insulating GaAs have been revealed by this method.
Stereoscopic X-ray angiography (2002)

There is a significant need for three-dimensional (3-D) spatial information in digital X-ray angiography (imaging of blood vessels). Availability of new, fast, c-arm systems, digital imagers and stereoscopic displays makes it possible to acquire stereoscopic X-ray angiograms. The authors develop a stereo-geometry model to explain acquisition geometry as well as basic aspects of stereoscopy, such as disparity, depth resolution and depth distortion. The authors also perform some simple experiments to verify the model. Finally, they present a set of guidelines for optimal stereoscopic acquisition.
Identification and Validation of Circulating MicroRNA Signatures for Breast Cancer Early Detection Based on Large Scale Tissue-Derived Data (2018)

The present study established a novel and effective method to identify biomarkers for early breast cancer. And the method, is also suitable for other cancer types. Furthermore, a combination of three miRNAs was identified as a prospective biomarker for breast cancer early detection.
Deformable templates in image sequences (2003)

The Bayesian reconstruction of the shape of an object in image sequences using deformable template techniques is considered. The object shape is represented by a prototype outline which is deformed under constraints of continuity and rigidity. The deformation of the template retains consistent shape characteristics whilst allowing variation and evolution of object shape over time. The reconstruction of single images using deformable templates allows incorporation of more detailed prior knowledge of expected image features than a simple local pixel dependence model. An application to a sequence of CCD animated digital images is given.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>