gebhart/patrepeval huggingface dataset:
Phase Calculation and its Use in Alloy Design Program for Nickel-Base Superalloys (1988)

A series of phase calculation equations for Y and Y' phases in nickelbase superalloys was established by regression analysis on the EPMA data obtained from 30 experimental or commercial alloys together with data from a Ni-Al binary phase diagram. By using these equations, an accurate calculation of 'Y/Y' equilibrium, at 9OOC, was made possible for various compositions of alloys, from Ni-Al binary to Ni-Co-Cr-Mo-W-Al-Ti-Nb-Ta-Hf-Re multi-component alloys. These phase calculation equations were substituted for those having been used in our alloy design program to extend the applicable composition range and to improve the accuracy of phase and property calculations of the program. Furthermore, a calculation equation for creep rupture life of SC alloys was established and adapted to the program. Using this new version of alloy design, the phase and property were successfully calculated for various types of 'Y' precipitation hardening nickel-base superalloys. Superalloys 1988 Edited by S: Reich&n, D.N. Duhl, G. Maurer, S. Antolovich and C. Lund The Mehlurgical Society, 1988
A route to glycals in the allal and gulal series: synthesis of the thiosugar of esperamicin A1 (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA route to glycals in the allal and gulal series: synthesis of the thiosugar of esperamicin A1Mark D. Wittman, Randall L. Halcomb, Samuel J. Danishefsky, Jerzy Golik, and Dolatrai VyasCite this: J. Org. Chem. 1990, 55, 7, 1979–1981Publication Date (Print):March 1, 1990Publication History Published online1 May 2002Published inissue 1 March 1990https://pubs.acs.org/doi/10.1021/jo00294a004https://doi.org/10.1021/jo00294a004research-articleACS PublicationsRequest reuse permissionsArticle Views844Altmetric-Citations63LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
A Graph Theoretic Algorithm for Placing Data and Parity to Tolerate Two Disk Failures in Disk Array Systems (2006)

In recent years commercial redundant arrays of inexpensive disks (RAID) systems have become increasingly popular because of their enhanced I/O bandwidths, large capacities and low cost. However, the continued demand for larger capacities at low cost, has led to the use of larger arrays with increased probability of random disk failures. Hence the need for RAID systems to tolerate two or more random disk failures without sacrificing performance or storage space. In this paper, we devise a novel graph-theoretic method for placing data and parity in an array of N disks (N /spl ges/ 3) to enable its recovery from any two random disk failures. We first provide an algorithm for the case when the number of disks N = P - 1, where P is a prime number, and then generalize the solution for any arbitrary N. We also determine the fraction of space used for storing parity in an array of N disks employing our algorithm, and show that this fraction has the optimal value of 21N for all N = P - 1. For illustration, this fraction and the percentage of its difference from the optimal ratio are graphed for values of N between 5 and 255. Finally, we describe a method for determining the data-blocks from where the reconstruction of two failed disks can be started in such an array.
Development of a Nascent Galectin-1 Chimeric Molecule for Studying the Role of Leukocyte Galectin-1 Ligands and Immune Disease Modulation (2010)

Galectin-1 (Gal-1), a β-galactoside-binding lectin, plays a profound role in modulating adaptive immune responses by altering the phenotype and fate of T cells. Experimental data showing recombinant Gal-1 (rGal-1) efficacy on T cell viability and cytokine production, nevertheless, is controversial due to the necessity of using stabilizing chemicals to help retain Gal-1 structure and function. To address this drawback, we developed a mouse Gal-1 human Ig chimera (Gal-1hFc) that did not need chemical stabilization for Gal-1 ligand recognition, apoptosis induction, and cytokine modulation in a variety of leukocyte models. At high concentrations, Gal-1hFc induced apoptosis in Gal-1 ligand(+) Th1 and Th17 cells, leukemic cells, and granulocytes from synovial fluids of patients with rheumatoid arthritis. Importantly, at low, more physiologic concentrations, Gal-1hFc retained its homodimeric form without losing functionality. Not only did Gal-1hFc-binding trigger IL-10 and Th2 cytokine expression in activated T cells, but members of the CD28 family and several other immunomodulatory molecules were upregulated. In a mouse model of contact hypersensitivity, we found that a non-Fc receptor-binding isoform of Gal-1hFc, Gal-1hFc2, alleviated T cell-dependent inflammation by increasing IL-4(+), IL-10(+), TGF-β(+), and CD25(high)/FoxP3(+) T cells, and by decreasing IFN-γ(+) and IL-17(+) T cells. Moreover, in human skin-resident T cell cultures, Gal-1hFc diminished IL-17(+) T cells and increased IL-4(+) and IL-10(+) T cells. Gal-1hFc will not only be a useful new tool for investigating the role of Gal-1 ligands in leukocyte death and cytokine stimulation, but for studying how Gal-1-Gal-1 ligand binding shapes the intensity of immune responses.
A Practical System for Privacy-Preserving Collaborative Filtering (2012)

Collaborative filtering is a widely-used technique in online services to enhance the accuracy of a recommender system. This technique, however, comes at the cost of users having to reveal their preferences, which has undesirable privacy implications. We propose a collaborative filtering system where the system does not observe the users' data and is still able to provide useful recommendations. Compared to prior systems, our emphasis is on building a practical system that can be reasonably used by a large number of users. Our approach involves creating a primitive to cluster similar users privately by modifying existing methods such as Locality Sensitive Hashing. Another technique we use is artificial ratings, as part of the process of privately predicting the rating for an item within a particular cluster. We evaluate our scheme on the Netflix Prize dataset, reporting the accuracy of our recommendations as a function of the privacy provided.
Highly electrostrictive poly(vinylidene fluoride–trifluoroethylene) networks (2001)

We report greatly improved electromechanical performance from a poly(vinylidene fluoride–trifluoroethylene) copolymer by chemical cross linking. Curing with an organic peroxide in combination with a free-radical trap, followed by crystallization, yields a ferroelectric network exhibiting a high electrostrictive response. The electric-field-induced strains were measured at low frequency using an air gap capacitance method and by a noninterferometric optical technique. At electric fields as low as 9 MV/m, longitudinal strains of 12% are obtained. This is more than two orders of magnitude better than conventional vinylidene fluoride materials, and more than an order of magnitude larger than the best results reported to date on any fluoropolymer. Since the mechanical modulus of the network is high (∼0.5 GPa), this work demonstrates the potential for extending the range of utility for polymer-based electromechanical materials.
Organophosphorus enamines: a new class of epoxy hardeners and adhesion promoters (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOrganophosphorus enamines: a new class of epoxy hardeners and adhesion promotersMilton D. Johnson, Mohinder S. Chattha, and Richard E. RobertsonCite this: Ind. Eng. Chem. Prod. Res. Dev. 1985, 24, 4, 565–567Publication Date (Print):December 1, 1985Publication History Published online1 May 2002Published inissue 1 December 1985https://doi.org/10.1021/i300020a014RIGHTS & PERMISSIONSArticle Views85Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (372 KB) Get e-Alerts
Determination of the Hall Thruster Operating Regimes (2002)

A quasi one-dimensional (1-D) steady-state model of the Hall thruster is presented. For the same discharge voltage two operating regimes are possible -- with and without the anode sheath. For given mass flow rate, magnetic field profile and discharge voltage a unique solution can be constructed, assuming that the thruster operates in one of the regimes. However, we show that for a given temperature profile the applied discharge voltage uniquely determines the operating regime: for discharge voltages greater than a certain value, the sheath disappears. That result is obtained over a wide range of incoming neutral velocities, channel lengths and widths, and cathode plane locations. It is also shown that a good correlation between the quasi 1-D model and experimental results can be achieved by selecting an appropriate electron mobility and temperature profile.
III-V-on-silicon photonic integrated circuits for optical interconnects (2015)

We review our work on the heterogeneous integration of III-V laser sources on the silicon photonics platform. These building blocks enable the realization of fully integrated silicon photonic transceivers for optical interconnect applications.
Purification of natural gas by liquid/liquid extraction with a polar solvent. [removal of CO/sub 2/, H/sub 2/S, water vapor, N/sub 2/, and He] (1976)

A gaseous stream (such as a ''sour'' natural gas stream) composed chiefly of a normally gaseous light hydrocarbon or alkane, such as methane, ethane, propane, or mixtures thereof, containing undesirable constituents, impurities or contaminants, such as carbon dioxide, hydrogen sulfide, water vapor, nitrogen and helium, is mixed with a polar organic liquid, such as methanol, or an aqueous solution of said liquid, such as an aqueous solution of methanol. The resulting mixture is cooled and liquefied and the resulting two-phase liquid mixture (comprising a light phase rich in the desired light hydrocarbon and an impurities-rich heavy phase of said polar organic liquid) is extracted with said polar organic liquid to recover said light hydrocarbon in the liquefied state, e.g., as liquefied, ''sweet'' natural gas.
Webpage Importance Analysis Using Conditional Markov Random Walk (2005)

In this paper, we propose a novel method to calculate the Web page importance based on a conditional Markov random walk model. The main assumption in this model is that given the hyperlinks in a Web page, users are not really randomly clicking one of them. Instead, many factors may bias their behaviors, for example, the anchor text, the content relevance and the previous experiences when visiting the Web site that a destination page belongs to. As one of the results, the user might tend to visit those pages in high-quality Web sites with higher probability. To implement this idea, we reformulate the Web graph to be a two-layer structure, and the Web page importance is calculated by conditional random walk in this new Web graph. Experiments on the topic distillation task of TREC 2003 Web track showed that our new method can achieve about 18% improvement on mean average precision (MAP) and 16% on precision at 10 (P@10) over the PageRank algorithm.
A holographic opaque document scanner (1977)

An opaque document scanner in which a moving hologram generates a locus of points from a stationary light beam on an opaque document and the same hologram or a similar one mounted for conjoint movement collects light energy reflected from the document at each point and focuses this energy onto a stationary detector to provide electrical signals corresponding to the information scanned on the document.
Echocardiogram videos: summarization, temporal segmentation and browsing (2003)

We present a system for the temporal segmentation, summarization, and browsing of the echocardiogram videos. Echocardiogram videos are video sequences produced by the ultrasound scanning of the heart, and are one of the main modalities of imaging the heart structure. Our approach combines the domain-specific knowledge and the automatic analysis of the spatio-temporal structure of the echocardiogram videos. The videos are temporally sampled using the embedded electrocardiogram graph. The consecutive sampled frames are compared based on the shape of the region of interest and the presence/absence of color to detect the boundaries between the different segments. The content of each segment of the video is summarized into two forms: the static and the dynamic summaries. Finally the summary is displayed in the user interface in an intuitive form for the purpose of browsing. Applications include digital medical image libraries, medical image management, and telemedicine.
Transdominant repressors for human T-cell leukemia virus type I rex and human immunodeficiency virus type 1 rev function (1991)

Human T-cell leukemia virus type I (HTLV-I) encodes a 27-kDa trans-acting gene product (Rex) which is involved in the regulated expression of transcripts coding for the viral structural proteins. We used oligonucleotide-directed mutagenesis to generate a series of mutant HTLV-I rex genes. Transient expression experiments demonstrated that 3 of 28 mutant proteins are functionally inactive on the homologous HTLV-I rex response element, whereas an additional 2 mutant proteins are functionally inactive on the heterologous human immunodeficiency virus type 1 rev response element. One of these mutants is able to suppress the function of the wild-type HTLV-I Rex protein in trans on the homologous rex response element sequence. Furthermore, all of these mutants are able to inhibit Rex function on the heterologous rev response element sequence. Intriguingly, only three of these mutants are able to inhibit the human immunodeficiency virus type 1 Rev protein in a dominant-negative manner.
Thermostable enzymes for industrial applications (1991)

The variety of thermostable (TS) enzymes has been steadily increasing for use in industrial applications, mainly as replacements for thermolabile (TL) enzymes. For example, TS amylases from Bacillus licheniformis and Bacillus stearothermophilus have replaced TL amylases from Bacillus subtilis. TS enzymes also have advantages in new areas such as cyclodextrin production. The TS cyclodextrin gtyeosyl transferase (CGTase) from Thermoanaerobacter sp. (95 ~ optimum) gives a higher productivity than the CGTase from Bacillus macerans (55 ~ optimum). In the area of enzymatic bleach boosting of wood pulps, a TS xylanase (Myceliopthera thermophila) would be advantageous over a TL xylanase (Trichoderma reesei), due to the high temperature of the incoming pulp. Not ',all TS enzymes are from thermophiles; the mesophile Candida antarctica produces a TS lipase which has a temperature optimum of 90 ~ when immobilized. The characterization of these enzymes will be described along with comparisons to some newly described TS enzymes.
Involvement of proteasome β1i subunit, LMP2, on development of uterin leiomyosarcma (2011)

Loss in LMP2 expression may be one of the risk factors for human uterine leiomyosarcoma. LMP2 may be a potential diagnostic-biomarker and targeted-molecule for a new therapeutic approach.
Capacitance detection type record stylus having a conductive shank (1986)

First Page
A dual-path TEQ structure for DMT-ADSL systems (2002)

Discrete Multitone (DMT) modulation is the industry standard for Asymmetrical Digital Subscriber Loop (ADSL) modems. DMT modulation allows for simplified equalization when the effective duration of the channel memory is shorter than the predefined length of the cyclic prefix (CP). A single time-domain equalizer (TEQ) is typically used to truncate the channel memory such that the data rate loss due to the use of the CP is reduced. Because the single TEQ is optimized over all sub channels, it is difficult to find an ideal solution in which the number of bits supported on each sub channel is optimized. This paper proposes a dual-path TEQ, which adds a second TEQ that is biased to selected sub channels to increase transmission throughput. The implementation complexity is lower than other band-partition equalization methods such as per tone equalization.
Wide temperature spectrum low leakage dynamic circuit technique for sub-65nm CMOS technologies (2006)

A new circuit technique is proposed in this paper for simultaneously reducing the subthreshold and gate oxide leakage power in domino logic circuits. PMOS-only sleep transistors are utilized along with a dual threshold voltage CMOS technology to place an idle domino circuit into a low leakage state. The effectiveness of the circuit technique is evaluated for a wide-temperature spectrum, considering both long and short idle periods. Assuming a short idle period at a temperature of 110/spl deg/C, up to 95.6% reduction in leakage power is observed as compared to standard dual threshold voltage domino circuits. Alternatively, assuming a long idle period at the room temperature, the circuit technique reduces the leakage power by up to 96.9% as compared to the standard dual threshold voltage domino logic circuits. Furthermore, by employing PMOS-only sleep transistors, the presented circuit technique reduces the total leakage power by up to 43.8% as compared to a previously published sleep scheme based on NMOS sleep transistors in a 45nm CMOS technology.
A 4D Stratigraphic Model Fitting Seismic Data for Sedimentary Basin Modelling (2004)

A003 A 4D STRATIGRAPHIC MODEL FITTING SEISMIC DATA FOR SEDIMENTARY BASIN MODELLING Introduction 1 G. DOBRANSZKY* R. MASSON E. ALBOUY & M.C. CACAS Institut Français du Pétrole 1 et 4 avenue du Bois Préau 92500 Rueil-Malmaison Abstract. Diffusive multi-lithology stratigraphic models are used in oil exploration in order to determine the geometry of sedimentary units and to characterise their sedimentary facies (depositional water depth sand/shale ratio…). One of the main difficulties in the use of such models is that their entry parameters (mainly accommodation input sediments diffusion coefficients) have to be inverted to fit the seismic and well log data.
Sampling of Charged Fine Particles by Motion Control under AC Field (2008)

When charged particles dispersed in air are introduced into a measurement cell, highly charged particles readily deposit on the surfaces, leading to a measurement error. To resolve this problem, a sampling device is designed and manufactured. The electrostatic force under AC field is used to control the motion of the particles close to the surfaces. The AC field is formed with many line electrodes arrayed on the surfaces by applying two AC voltages of a 180 degree phase difference. The effect of the operational conditions such as AC voltage and frequency on the particle deposition is studied and the performance of the sampling device is evaluated. Also, to verify the applicability of the device to actual measurement systems, an experiment is carried out by combining with a system to measure particle charge distribution.
2-SUBSTITUTED PI SYSTEM DERIVATIVES OF ADENOSINE THAT ARE CORONARY VASODILATORS ACTING VIA THE A<sub>2A</sub>ADENOSINE RECEPTOR (2001)

Compound 20 (CVT-3146--a 2-[(N-1-(4-N-methylcarboxamidopyrazolyl)] adenosine derivative) and compound 31 (CVT-3033--a 2-[(4-(1-N-pentylpyrazolyl)] adenosine derivative), were found to be short acting functionally selective coronary vasodilators (CV t0.5 = 5.2 +/- 0.2 and 3.4 +/- 0.5 min, respectively--rat isolated heart 50% reversal time) with good potency (EC50S = 6.4 +/- 1.2 nM and 67.9 +/- 16.7 nM, respectively), but they possess low affinity for the ADO A2A receptor (Ki = 1122 +/- 323 nM and 2138 +/- 952 nM, respectively; pig striatum).
DDIS-06. Ku 70/80 IN GLIOMA - TARGETING WITH APTAMERS (2016)

Aptamers are in vitro generated DNA and RNA sequences. These are randomly present in a library with common primers. Aptamer sequences have multiple permutations and combinations of nucleotides and are then ‘selected’, using Sequential Enumeration of Ligands by Exponential Enrichment (SELEX) towards the desired target, known or unknown. Modified aptamers, based on published sequences against glioma cell lines and novel aptamers were used in the project to identify and confirm the targets. Commercially available glioma cell lines and short term cultures from anonymised patient tissue were used. Fluorescent and biotin conjugated aptamers were incubated with glioma cell cultures and imaged using confocal and light microscopy. Aptamers were then reacted with glial cell lysate and subjected to precipitation using streptavidin agarose beads and gel electrophoresis. Proteins were analysed by mass spectroscopy. Ku 70 and Ku80 were identified as the most abundant protein when compared to control aptamer precipitation. Western blot analysis and siRNA knockdown was used with immunostaining, to further confirm the target. Ku70 (X-ray Repair Cross Complementing protein 6), Ku80 (X-ray Repair Cross Complementing protein 5) were precipitated along with known proteins and few unnamed proteins. Western blot analysis confirmed precipitation of Ku70 and Ku80 mainly when compared to the control aptamer. DAB staining of cell cultures revealed over-expression of Ku70 and Ku80 throughout the glioma cell cultures. siRNA knock down showed reduced binding of the aptamer to the nucleus when compared to untreated cell cultures. Certain aptamers appear to readily bind to DNA repair proteins Ku70 and Ku80 and could be used for developing targeted therapy towards glioma. Western and knockdown analysis, confirm the specificity of binding and leads the way for in-vivo testing of aptamers.