gebhart/patrepeval huggingface dataset:
Cockpit Lighting Compatibility With Image Intensification Night Imaging Systems: Issues And Answers (1989)

Night imaging systems based on image intensification (I<sup>2</sup>) tubes are a major factor in the night operation capability of U.S. Army rotary-wing aircraft. A major problem associated with the use of these systems is the detrimental effect caused by internal cockpit lighting. Instrument lamps, caution lamps, utility lights, and other light sources inside the cockpit activate the bright source protection control circuits of the intensification tubes, thereby reducing their sensitivity to external natural and artificial illumination. In 1986, a Tri-Service specification, MIL-L-85762, "Lighting, aircraft, interior, night vision imaging system compatible," was adopted to resolve the cockpit lighting problems. MIL-L-85762 defines the measurement instrumentation and techniques required to certify lighting components as "ANVIS compatible." The specification does not address compatibility problems associated with AN/PVS-5 usage. Ongoing efforts related to MIL-L-85762 include characterization of lighting incompatibilities in current U.S. Army aircraft, implementation of programs to modify the lighting in incompatible cockpits, and certification of proposed lighting components for future aircraft systems. Additional work has been done to provide "near compatible" solutions to lighting problems associated with the use of AN/PVS-5 systems.
Vaccination by Genetically Modified Dendritic Cells Expressing a Truncated<b><i>neu</i></b>Oncogene Prevents Development of Breast Cancer in Transgenic Mice (2004)

Dendritic cells (DCs) are powerful antigen-presenting cells that process antigens and present peptide epitopes in the context of the major histocompatibility complex molecules to generate immune responses. DCs are being studied as potential anticancer vaccines because of their ability to present antigens to naive T cells and to stimulate the expansion of antigen-specific T-cell populations. We investigated an antitumor vaccination using DCs modified by transfer of a nonsignaling neu oncogene, a homologue of human HER-2/neu, in a transgenic model of breast cancer. BALB-neuT mice develop breast cancers as a consequence of mammary gland-specific expression of an activated neu oncogene. We vaccinated BALB-neuT mice with bone marrow-derived DCs transduced with Ad.Neu, a recombinant adenovirus expressing a truncated neu oncoprotein. The vaccine stimulated the production of specific anti-neu antibodies, enhanced interferon-gamma expression by T cells, and prevented or delayed the onset of mammary carcinomas in the mice. Over 65% of vaccinated mice remained tumor free at 28 weeks of age, whereas all of the mice in the control groups developed tumors. When challenged with a neu-expressing breast cancer cell line, vaccinated tumor-free animals had delayed tumor growth compared with controls. The antitumor effect of the vaccine was specific for expression of neu. Studies showed that CD4+ T cells were required in order to generate antitumor immunity. Importantly, the effectiveness of the vaccine was not diminished by preexisting immunity to adenovirus, whereas the protection afforded by vaccination that used direct injection of Ad.Neu was markedly reduced in mice with anti-adenovirus antibody titers. DCs modified by recombinant adenoviruses expressing tumor-associated antigens may provide an effective antitumor vaccination strategy.
Child Well Analysis from Poroelastic Pressure Responses on Parent Wells in the Eagle Ford (2019)

Abstract The industry continues to face a challenge understanding and optimizing completion strategies to minimize the impact of infill development on existing wells and achieve larger Stimulated Reservoir Volume (SRV) on infill wells. This paper presents a cost-effective technique for evaluating parent-child interaction using poroelastic pressure responses on the parent wells. The method was employed on a four-well pad in the Eagle Ford to understand diversion effectiveness and the extent of offset depletion. The case study comprised the analysis of pressure data sets, covering wellhead pressure data from the nearby parent wells. The method quantifies and interprets pressure signal magnitude and its transient behavior for each completed stage. The well offsetting the parent well was completed using two different completion designs. One half of the lateral was completed without employing diversion, while the other half employed a specific diversion strategy. The primary goal of the case study was to demarcate the areal extent and degree of depletion around the existing wells and determine the effectiveness of using diversion in inhibiting growth towards parent wells. The analysis determined fluid and fracture pathways, mainly seen driven by formation stresses, depletion, and completion design in each stage. The case study compared the effects of employing diversion vs. not employing diversion, using the magnitude of pressure responses felt by the parent well. The initiation points of the pressure signals, as felt by the offset wells on each side quantified how quickly and in which direction the newly treated fractures were growing. The pressure responses from multiple parent wells were correlated to understand the areal extent of depletion around each offset producer. This ultimately promotes understanding the difference in pre and post production of the wells and optimizes infill completions for future development. Cross well analysis using poroelastic pressure responses is easy to implement and very cost-effective. The proposed method provides a workflow to analyze offset pressure data in a consistent and reproducible manner. This method affords the industry a better understanding of parent well damage and mitigation of child well productivity loss.
Hepatocyte Growth Factor/c-MET Axis-mediated Tropism of Cord Blood-derived Unrestricted Somatic Stem Cells for Neuronal Injury (2008)

An under-agarose chemotaxis assay was used to investigate whether unrestricted somatic stem cells (USSC) that were recently characterized in human cord blood are attracted by neuronal injury in vitro. USSC migrated toward extracts of post-ischemic brain tissue of mice in which stroke had been induced. Moreover, apoptotic neurons secrete factors that strongly attracted USSC, whereas necrotic and healthy neurons did not. Investigating the expression of growth factors and chemokines in lesioned brain tissue and neurons and of their respective receptors in USSC revealed expression of hepatocyte growth factor (HGF) in post-ischemic brain and in apoptotic but not in necrotic neurons and of the HGF receptor c-MET in USSC. Neuronal lesion-triggered migration was observed in vitro and in vivo only when c-MET was expressed at a high level in USSC. Neutralization of the bioactivity of HGF with an antibody inhibited migration of USSC toward neuronal injury. This, together with the finding that human recombinant HGF attracts USSC, document that HGF signaling is necessary for the tropism of USSC for neuronal injury. Our data demonstrate that USSC have the capacity to migrate toward apoptotic neurons and injured brain. Together with their neural differentiation potential, this suggests a neuroregenerative potential of USSC. Moreover, we provide evidence for a hitherto unrecognized pivotal role of the HGF/c-MET axis in guiding stem cells toward brain injury, which may partly account for the capability of HGF to improve function in the diseased central nervous system.
FP-Viz: Visual Frequent Pattern Mining (2005)

Frequent pattern mining plays an essential role in many data analysis tasks including association-, correlation-, and causality analysis and has broad applications. Examples are market basket analysis and web click stream analysis. Al-though a number of efficient methods for mining frequent patterns where proposed in the past, there exist only a small number of visual exploration tools for discovering frequent patterns. In this paper we present a novel visualization tech-nique for exploring frequent itemsets interactivly, based on a radial visual layout approach.
ChemInform Abstract: REDUCTION OF β‐ALKYLTHIOα,β‐UNSATURATED KETONES(R(1)COCH=C(R(2))SR(3) WITH LIALH4 OR NABH4: CONVERSION TO α,β‐UNSATURATED KETONES (R(1)CH=CHCOR(2) (1980)

Abstract Ungesättigte Ketone (I) mit Mercaptosubstituenten werden mit Lithiumalanat zu den Vinylketonen (II) reduziert.
Structural Determinants of KvLQT1 Control by the KCNE Family of Proteins (2001)

KvLQT1 is a Shaker-like voltage-gated potassium channel that when complexed with minK (KCNE1) produces the slowly activating delayed rectifier I(ks). The emerging family of KCNE1-related peptides includes KCNE1 and KCNE3, both of which complex with KvLQT1 to produce functionally distinct currents. Namely I(ks), the slowly activating delayed rectifier current, is produced by KvLQT1/KCNE1, whereas KvLQT1/KCNE3 yields a more rapidly activating current with a distinct constitutively active component. We exploited these functional differences and the general structural similarities of KCNE1 and KCNE3 to study which physical regions are critical for control of KvLQT1 by making chimerical constructs of KCNE1 and KCNE3. By using this approach, we have found that a three-amino acid stretch within the transmembrane domain is necessary and sufficient to confer specificity of control of activation kinetics by KCNE1 and KCNE3. Moreover, chimera analysis showed that different regions within the transmembrane domain control deactivation rates. Our results help to provide a basis for understanding the mechanism by which KCNE proteins control K(+) channel activity.
The multiscalar architecture (1993)

The centerpiece of this thesis is a new processing paradigm for exploiting instruction level parallelism. This paradigm, called the multiscalar paradigm, splits the program into many smaller tasks, and exploits fine-grain parallelism by executing multiple, possibly (control and/or data) depen-dent tasks in parallel using multiple processing elements. Splitting the instruction stream at statically determined boundaries allows the compiler to pass substantial information about the tasks to the hardware. The processing paradigm can be viewed as extensions of the superscalar and multiprocess-ing paradigms, and shares a number of properties of the sequential processing model and the dataflow processing model. The multiscalar paradigm is easily realizable, and we describe an implementation of the multis-calar paradigm, called the multiscalar processor. The central idea here is to connect multiple sequen-tial processors, in a decoupled and decentralized manner, to achieve overall multiple issue. The mul-tiscalar processor supports speculative execution, allows arbitrary dynamic code motion (facilitated by an efficient hardware memory disambiguation mechanism), exploits communication localities, and does all of these with hardware that is fairly straightforward to build. Other desirable aspects of the
Solvent Modulated Polymorphism of Sodium Stearate Crystals Studied by X-ray Diffraction, Solid-State NMR, and Cryo-SEM (2001)

Ternary crystalline dispersions of 10 wt % sodium stearate (NaSt) in mixtures of water and propylene glycol (PG) have been investigated at the atomic, molecular, and microscopic levels. Two lamellar crystalline structures, α-NaSt and β-NaSt, have been determined by X-ray diffraction. Compared with β-NaSt, α-NaSt exhibits a larger bilayer thickness, a more ordered packing of hydrocarbon chains, and dissolves at a lower temperature in the PG/H2O mixture. A transformation from β-NaSt to α-NaSt is observed upon aging in a PG concentration range of 60−95 wt % in mixtures of H2O and PG. The aging transformation progresses faster and to a greater extent as the PG content increases. Additionally, the fibrous crystallites of α-NaSt are more bundled and oriented compared to those of β-NaSt, as revealed by two-dimensional SAXS (small-angle X-ray scattering) and cryo-SEM (cryogenic scanning electron microscopy). The conformation and mobility of the alkane chains in α-NaSt and β-NaSt have been further studied by solid-state 13C CP MAS (cross-polarization magic-angle spinning) NMR. A greater percentage of trans chain conformation is found in α-NaSt, and the rigidity of the chains is higher. A stronger association of PG with β-NaSt crystals than with α-NaSt crystals is also indicated by the appearance of the PG carbon resonances in the solid-state NMR spectrum.
Design and validation of a real-time spiking-neural-network decoder for brain–machine interfaces (2013)

These results demonstrate the tractability of SNN implementations of statistical signal processing algorithms on different monkeys and for several tasks, suggesting that a SNN decoder, implemented on a neuromorphic chip, may be a feasible computational platform for low-power fully-implanted prostheses. The validation of this closed-loop decoder system and the demonstration of its robustness and generalization hold promise for SNN implementations on an ultra-low power neuromorphic chip using the NEF.
Fluorescence probe studies of aqueous solution interaction between sodium dodecyl sulfate and anionic polyelectrolytes (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFluorescence probe studies of aqueous solution interaction between sodium dodecyl sulfate and anionic polyelectrolytesM. J. McGlade, F. J. Randall, and N. TcheurekdjianCite this: Macromolecules 1987, 20, 8, 1782–1786Publication Date (Print):August 1, 1987Publication History Published online1 May 2002Published inissue 1 August 1987https://pubs.acs.org/doi/10.1021/ma00174a013https://doi.org/10.1021/ma00174a013research-articleACS PublicationsRequest reuse permissionsArticle Views295Altmetric-Citations39LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The 'how' and 'why' of persistent information security (2006)

A file level information security technology that applies everywhere, every time, is introduced. The security is always 'on', as much 'in the wild' as behind the firewall or in the VPN tunnel. The broad strokes of structure and operation are discussed in terms of a specific system, RightsEnforcer. The technology is currently being deployed in the Adaptive Risk Management Lab at the University of New Brunswick as part of a testbed supporting emergency response operations.
The Problem of Who Should Intervene (2010)

Abstract This chapter sets the scope for the rest of the book. It outlines the problems caused by the lack of clarity surrounding who should intervene and, in doing so, identifies two specific questions that the book is concerned with ‘Who has the right to intervene?’ and ‘Who has the duty to intervene?’. It also examines the changes in the responsibility to protect doctrine from the International Commission on Intervention and State Sovereignty (ICISS) report to the 2005 UN World Summit agreement. It goes on to consider two central questions in the ethics of humanitarian intervention: (a) Whether humanitarian intervention is a duty or only a right?(b) When can there be just cause for humanitarian intervention? The final section provides definitions of ‘humanitarian intervention’ and ‘legitimacy’.
Multiple members of the plasminogen-apolipoprotein(a) gene family associated with thrombosis (1992)

Plasminogen and apolipoprotein(a) [apo(a)] are closely related plasma proteins that are associated with hereditary thrombophilia. Low plasminogen levels are found in some patients who developed venous thrombosis, while a population with high plasma concentrations of apo(a) have a higher incidence of arterial thrombosis. Two different genes coding for human apo(a) have been isolated and characterized in order to study and compare these genes with four other closely related genes in the plasminogen-apo(a) gene family. These include the gene coding for plasminogen, two unique plasminogen-related genes, and a gene coding for hepatocyte growth factor. Nucleotide sequence analysis of these genes revealed that the exons and their boundaries of the genes for plasminogen and apo(a), and the plasminogen-related genes, differ only 1-5% in sequence. The types of exon/intron junctions and positions of introns in the molecules are also exactly identical, suggesting that these genes have evolved from an ancestral plasminogen gene via duplication and exon shuffling. By utilizing these results, gene-specific probes have been designed for the analysis of each of the genes in this gene family. The plasminogen and two apo(a) genes were all localized to chromosome 6 by employing the gene-specific primers and genomic DNAs from human-hamster cell hybrids. These data also make it possible to characterize the apo(a) and plasminogen genes in individuals by in vitro amplification.
CA Magazine May 2015 (2015)

With the NHS at the forefront of the debate in the UK General Election, this month’s issue of The CA features Paolo Pieri CA, CFO with private healthcare group Circle Holdings.
RapidDNA: a game changer in the law enforcement identification stakes (2013)

If you are a fan of the CSI genre of US crime soaps, you may have noticed the increasing use of DNA-based identification as a means of forensic identification analysis over the last few years.
Frequency-domain equalization with interference rejection combining for single carrier multiple-input multiple-output underwater acoustic communications (2020)

This paper describes a three-step frequency-domain equalization scheme for multiple-input multiple-output (MIMO) underwater acoustic communication. First, an iterative least-squares channel estimation method is developed to enhance the accuracy of channel estimation in MIMO communication. The interference rejection combining method is then adopted to suppress co-channel interference based on the estimated MIMO channels. This technique exploits the correlation between the interference received through different channels. Finally, a decision feedback equalizer embedded with a digital phase-lock loop is cascaded before the final determination of equalized symbols to compensate the phase rotation. Experimental results show that the bit error rates of the proposed scheme can be several orders of magnitude lower than those of conventional frequency-domain equalization schemes.
Exchange coupling torque in ferrimagnetic Co/Gd bilayer maximized near angular momentum compensation temperature (2018)

Highly efficient current-induced motion of chiral domain walls was recently demonstrated in synthetic antiferromagnetic (SAF) structures due to an exchange coupling torque (ECT). The ECT derives from the antiferromagnetic exchange coupling through a ruthenium spacer layer between the two perpendicularly magnetized layers that comprise the SAF. Here we report that the same ECT mechanism applies to ferrimagnetic bi-layers formed from adjacent Co and Gd layers. In particular, we show that the ECT is maximized at the temperature T<sub>A</sub> where the Co and Gd angular momenta balance each other, rather than at their magnetization compensation temperature T<sub>M</sub>. The current induced velocity of the domain walls is highly sensitive to longitudinal magnetic fields but we show that this not the case near T<sub>A</sub>. Our studies provide new insight into the ECT mechanism for ferrimagnetic systems. The high efficiency of the ECT makes it important for advanced domain wall based spintronic devices.
Research on Personal Credit Evaluation Based on Machine Learning Algorithm (2021)

With the rapid development of Internet finance and consumer credit, it is necessary to establish a reasonable personal credit evaluation model. This paper discusses the accuracy of six general personal credit evaluation models based on the Give Me Some Credit data set from Kaggle. A multiple-average machine learning model is established to improve the stability of the result. The research shows the NB classifier, Support Vector Machines, Random Forest and BP Neural Network have good prediction effect on individual credit default risk, while the accuracy of Logical Regression and Stepwise Regression is relatively low. The multiple averaging method can effectively reduce the volatility of the results, and the accuracy will not be significantly reduced under different proportion of training set and prediction set.
Anti-Profiteering Provisions under GST:A Move Towards Ensuring Consumer Welfare (2018)

One of the intended benefits of GST is to ensure reduced prices to consumers by eliminating tax cascading and ensuring availability of tax credit at various stages of production. However, this benefit may not be achieved if the suppliers do not pass on the benefits to the consumers and indulge in illegal profiteering. Therefore, the government has introduced anti-profiteering provisions in GST laws wherein suppliers of goods and services must pass on any reduction in the rate of tax or the benefit of input tax credit to consumers by way of commensurate reduction in prices. If this is not done, the consumer’s interest is protected by the National Anti-profiteering Authority. While it is difficult to reach a definitive conclusion on what implies ‘commensurate’ in a complex production system with multiple stages, these provisions are likely to be a step forward in ensuring consumer welfare.
Automated Detection of Prevalent Mutations in <i>BRCA1</i> and <i>BRCA2</i> Genes, Using a Fluorogenic PCR Allelic Discrimination Assay (1997)

Mutations in the genes BRCA1 and BRCA2 account for 5%-10% of familial early onset breast cancer. Identification of these mutations allows molecular diagnosis for breast cancer susceptibility. A high through-put automated PCR allelic discrimination assay (ADA) was developed to detect the prevalent mutations in these genes. Two allele specific oligonucleotides (ASO) are directly used in the PCR reaction, in both of which the fluorescent reporter and quencher dyes are attached to the 5' and 3' ends, respectively. During PCR, fluorescence is generated after cleavage of the annealed ASO by the 5' nuclease activity of Taq polymerase. The wild-type BRCA sequence is distinguished from the mutant sequence by the differential fluorescence emission of two different reporter dyes. The sensitivity of ADA is at the level of a single cell following a nested PCR. Eighty-six patient samples can be analyzed for each mutation in 15-min post-PCR without the need for radioactivity, gel electrophoresis, or membrane blotting/hybridization.
A MÁTRIA E O MAL EM NATÁLIA CORREIA (2004)

espanhol Miguel de Unamuno fundou o termo matriotismo para designar um sentimento alternativo que respondesse falncia do sentimento patritico. A matriz de derivao morfolgica do novo vocbulo era a palavra matria, que Unamuno considerava um neologismo, traduo do germnico Mutterland, terra me associada Europa, por oposio a Vaterland, ptria ou terra pai que delimita o territrio da nossa origem biolgica e social. Porm, a conceptualizao de Unamuno repousava num vitalismo racionalista que,