gebhart/patrepeval huggingface dataset:
Output-Feedback-Based $H_{\infty}$ Control for Vehicle Suspension Systems With Control Delay (2013)

This paper deals with the problem of output-feedback H <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">∞</sub> control for a class of active quarter-car suspension systems with control delay. The dynamic system of the suspension systems is first formed in terms of the control objectives, i.e., ride comfort, road holding, suspension deflection, and maximum actuator control force. Then, the objective is to the design of the dynamic output-feedback H <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">∞</sub> controller in order to ensure asymptotic stability of the closed-loop system with H <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">∞</sub> disturbance attenuation level and the output constraints. Furthermore, using Lyapunov theory and linear matrix inequality (LMI) approach, the existence of admissible controllers is formulated in terms of LMIs. With these satisfied conditions, a desired dynamic output-feedback controller can be readily constructed. Finally, a quarter-vehicle model is exploited to demonstrate the effectiveness of the proposed method.
Non-equilibrium enzyme immunoassay of gentamicin. (1978)

We describe a fast, accurate non-equilibrium enzyme immunoassay for serum gentamicin. With use of isokinetic conditions an assay takes a total of 12 min, including regeneration of the immunosorbent. The coefficient of correlation between the present method and conventional microbiological assays was 0.98.
Direct Analysis of Proteins in Mixtures: Application to Protein Complexes (2003)

Tandem mass spectrometry is a powerful mixture analysis technique suitable for sequence analysis of peptides (1). A tandem mass spectrometer uses two stages of analysis to generate structurally informative fragmentation. The first stage involves separation of an ion from all the other ions that may be entering the mass spectrometer analyser. Ion isolation can be accomplished by separating an ion in time or in space; these processes are used by ion trap instruments or by triple quadmpole instruments, respectively (2–4). The isolated ion is then subjected to ion activation using energetic gas-phase collisions. In the second analysis stage, the mass-to-charge ratio (m/z) values of the fragmentation products are determined. This method is used for protein sequence analysis by first creating a collection of peptides using site-specific enzymatic or chemical proteolysis (1). The collection of peptides is introduced into the mass spectrometer through a separation technique (liquid chromatography [LC] or capillary electrophoresis [CE]) or by batch infusion and finally ionized using electrospray ionization (5–7). Computer control of the data acquisition process allows highly efficient acquisition of these tandem mass spectra as well as unassisted operation of the mass spectrometer (8,9). The resulting tandem mass spectra can reveal the amino acid sequence of peptides by interpretation, or, with the recent expansion of sequence databases, the tandem mass spectra can be used to search protein and nucleotide sequence databases directly to identify the amino acid sequence represented by the spectrum (l,8,10,11). Because tandem mass spectra can be acquired quickly and selectively on individual peptides present, the identities of proteins in a mixture can be determined (10,12,13).
Evaluation of the Illinois Soil Nitrogen Test in the North Central Region of the United States (2008)

Recently the Illinois soil nitrogen test (ISNT) was proposed as a means to identify fields where corn ( Zea mays L.) will not respond to additional N fertilizer and which may also be used to predict the economic optimum N rate (EONR). Data from 96 corn N rate response trials across Iowa, Illinois, Michigan, Minnesota, Nebraska, and Wisconsin were compiled to evaluate the usefulness of the ISNT in identifying nonresponsive fields, predicting EONR, and estimating mineralizable N. At each trial site, multiple rates of fertilizer N were applied, including zero N and nonyield limiting rates. Corn was grown following several crops. The ISNT could not accurately predict nonresponsive sites, nor could it reliably estimate EONR. Subsetting the data based on soil drainage class and previous crop did not improve the predictive capability of the ISNT even though ISNT values were significantly different among previous crops and soil drainage classes. The ISNT was strongly correlated to soil organic matter (OM) and was apparently measuring a constant fraction of total soil N (TN). The lack of correlation between the ISNT and relative N uptake (check plot N uptake/N uptake at the maximum N rate) suggests that the ISNT is not measuring the readily mineralizable fraction of soil N. Based on results of this project, the ISNT is not suggested for use in adjusting N rate recommendations for corn in the North Central Region (Corn Belt) of the United States.
Parallel, Object-Oriented, and Active Knowledge Base Systems (1998)

Knowledge Base Systems are an integration of conventional database systems with Artificial Intelligence techniques. They provide inference capabilities to the database system by encapsulating the know
An intelligent depth-based obstacle detection system for visually-impaired aid applications (2012)

In this paper, we present a robust depth-based obstacle detection system in computer vision. The system aims to assist the visually-impaired in detecting obstacles with distance information for safety. With analysis of the depth map, segmentation and noise elimination are adopted to distinguish different objects according to the related depth information. Obstacle extraction mechanism is proposed to capture obstacles by various object proprieties revealing in the depth map. The proposed system can also be applied to emerging vision-based mobile applications, such as robots, intelligent vehicle navigation, and dynamic surveillance systems. Experimental results demonstrate the proposed system achieves high accuracy. In the indoor environment, the average detection rate is above 96.1%. Even in the outdoor environment or in complete darkness, 93.7% detection rate is achieved on average.
Effects of Changes in Body Weight and Insulin Resistance on Inflammation and Endothelial Function in Morbid Obesity after Bariatric Surgery (2005)

Metabolic alterations such as insulin resistance are thought to underlie the endothelial dysfunction and low grade inflammation found in morbid obesity. Twenty-six morbidly obese patients, aged 39.0 +/- 10.0 (mean +/- sd), were evaluated before and 4.2 +/- 0.8 months after bariatric surgery. A marked increment in the insulin sensitivity index (S(I)) and the endothelium-dependent vasodilatory response in a dorsal hand vein was observed after weight loss following bariatric surgery. Circulating levels of E-selectin, P-selectin, plasminogen activator inhibitor-1, and von Willebrand factor, which were higher than those in the control group, decreased significantly after surgery. Plasma vascular cell adhesion molecule-1, angiotensin-converting enzyme, intercellular adhesion molecule-1, thrombomodulin, and plasma and intraplatelet cGMP levels did not change after weight loss. All inflammatory markers were higher in morbidly obese patients. After surgery, C- reactive protein and sialic acid diminished, whereas circulating levels of IL-6, TNF-alpha, and its soluble receptors did not. Positive correlations were found between changes in adiposity and S(I) and changes in C-reactive protein and between changes in sialic acid and changes in endothelial function. In conclusion, a marked improvement in S(I), endothelial function, and low grade inflammation was observed in the weight-losing, morbidly obese patients after bariatric surgery. S(I) and adiposity appear to play roles in obesity-related, low grade inflammation that contribute to the endothelial dysfunction observed in morbid obesity.
Treelike networks accelerating capillary flow (2014)

Transport in treelike networks has received wide attention in natural systems, oil recovery, microelectronic cooling systems, and textiles. Existing studies are focused on transport behaviors under a constant potential difference (including pressure, temperature, and voltage) in a steady state [B. Yu and B. Li, Phys. Rev. E 73, 066302 (2006); J. Chen, B. Yu, P. Xu, and Y. Li, Phys. Rev. E 75, 056301 (2007)]. However, dynamic (time-dependent) transport in such systems has rarely been concerned. In this work, we theoretically investigate the dynamics of capillary flow in treelike networks and design the distribution of radius and length of local branches for the fastest capillary flow. It is demonstrated that capillary flow in the optimized tree networks is faster than in traditional parallel tube nets under fixed constraints. As well, the flow time of the liquid is found to increase approximately linearly with penetration distance, which differs from Washburn's classic description that flow time increases as the square of penetration distance in a uniform tube.
An Alternating Direction Method of Multipliers Based Approach for PMU Data Recovery (2018)

This paper presents a novel algorithm for recovering missing phasor measurement unit (PMU) data. Due to the low-rank property of PMU data, missing measurement recovery can be formulated as a low-rank matrix-completion problem. Based on maximum-margin matrix factorization, we propose an efficient algorithm, alternating direction method of multipliers (ADMM), for solving the matrix completion problem. Compared to existing approaches, the proposed ADMM based algorithm does not need to estimate the rank of the target data matrix and provides better performance in computation complexity. Since PMU data are transferred through insecure and delayed communications, we consider the case of measurements missing from all PMU channels in several sampling instants and provide the strategies of reshaping the matrix composed by the received PMU data for the recovery. Numerical results using real PMU measurements from State Grid Jiangsu Electric Power Company illustrate the effectiveness and efficiency of the proposed approaches.
An Experimental Study on Replay Attack Detection Using Spoofing Clues from both Voiced and Non-Voiced Segments (2021)

The spoofing clues with reverberation, channel and environmental noise are intertwined with the genuine speaker voice, making the task for replay attack detection challenging. In this study, we propose a novel approach to make full use of the replay clues of a whole utterance, by separately extracting different features from voiced and non-voiced segments and training separate Gaussian Mixed Models. First, a joint voice activity detector is adopted to get accurate boundaries of the different segments. Then this paper extracts Constant-Q Cepstral Coefficients and Inverse Mel Frequency Cepstral Coefficients from voiced and non-voiced segments respectively. Finally, a Score Calibrator Toolkit is used to fuse the scores of voiced and non-voiced segments. The result on evaluation set of ASVspoof 2017 V2.0 corpus shows that our proposed method yields an 18.4% relative reduction in equal error ratecompared to the CQCC-CMVN baseline system.
Measurement and Optimization of Metal‐Nanoparticle‐Induced Luminescence Enhancement Factors in a Crossed‐Optical Fiber Configuration (2010)

A crossed‐optical‐fiber configuration comprised of silver nanoparticles covalently attached to the core of an optical fiber and labeled with luminescent ruthenium molecules is reported. A second optical fiber was placed at right angle of the fiber containing the nanoparticle/ruthenium, to form a fiber‐fiber junction, and it was used to detect the luminescence from the ruthenium molecules bound to the first fiber. To employ the effect of metal‐enhanced luminescence, the ruthenium complex was kept at an appropriate distance from the nanoparticles by polyelectrolyte spacer layers. For silver nanospheres, nanotriangles and nanorods and for spacer‐layer thicknesses from 2–14 nm luminescence‐enhancement factors were determined. A 27‐fold luminescence enhancement was found when the ruthenium complex was placed 4 nm from silver nanotriangles. Finally, a calibration curve for the oxygen dependence of luminescence intensities and lifetimes of ruthenium complex is presented suggesting that the oxygen sensing capabilities of the nanoengineered‐ruthenium complex are maintained.
What should we be measuring in behavioral studies of chronic pain in animals? (2004)

Department of Psychology and Centre for Research on Pain, McGill University, 1205 Dr Penfield Ave., Montreal, Que., Canada H3A 1B1 *Corresponding author. Tel.: +1 514 398 6085; fax: +1 514 398 4896. E-mail: [email protected] Submitted July 9, 2004.
Linear and Nonlinear Optical Properties of Semiconductor Clusters (1988)

Polymers and glasses doped with small semiconductor clusters represent a new class of materials. These materials are interesting for two reasons. First, the size of the semicondutor clusters can be controlled to vary from a few to hundreds of Å. This provides a vehicle to study the transition of a semiconductor from molecular to bulk. Secondly, by doping polymers or glasses with these small semiconductor clusters, utilizing their large resonant third order nonlinearity, new optically nonlinear composite materials can be prepared. In this paper we will discuss the linear and nonlinear optical properties of PbS and CdS clusters in polymer films.
Demonstration of PLOW (2007)

We describe a system that can learn new procedure models effectively from one demonstration by the user. Previous work to learn tasks through observing a demonstration (e.g., Lent & Laird, 2001) has required observing many examples of the same task. One-shot learning of tasks presents a significant challenge because the observed sequence is inherently incomplete -- the user only performs the steps required for the current situation. Furthermore, their decision-making processes, which reflect the control structures in the procedure, are not revealed.
The Description of the Regeneration Behavior of Diesel Particulate Traps with the Aid of a Mathematical Model (1983)

<div class="htmlview paragraph">Monolithic ceramic filters, suitable for reducing particulate emissions to within the 0,2 g/mile emissions limit, are intermittantly loaded and regenerated. A mathematical model was developed in order to describe the processes which take place in the filter during regeneration. The basis of the calculation model, such as reaction kinetics, heat and mass transfer, energy and mass balance, and flow performance are explained. Filter temperature, soot oxidation and exhaust flow behavior are described over the length of a filter channel.</div> <div class="htmlview paragraph">A calculated and measured regeneration sequence for an engine operating point near engine full load are illustrated and compared. The results show that due to the prevailing higher temperatures, an intensified soot oxidation occurs at the rear of the channel. A comparison of calculated and measured regeneration requirements as well as salient oxidation parameters leads to the definition of an engine operating range where the minimum regeneration requirements are satisfied. In this range the filtered soot mass and the oxidizing soot mass are in equilibrium.</div>
Stiffness and design for strength of trapezoidal Belleville springs (2011)

Belleville springs or coned disc springs are commonly used in machine design. The geometric dimensions of the spring and the determination of non-linear force–displacement curve are regulated by different standards. However, the theory behind Belleville spring design standards is founded on a study published in 1936. Furthermore, the common spring design with cross-sections of uniform thickness poses problems in terms of non-uniformity of stress distribution. In view of this, non-linear three-dimensional finite element analyses of spring designs including uniform or variable thickness are carried out in this paper. Finite element results are compared with analytical predictions and critically analysed in terms of the effect of Poisson ratio, overall stiffness, and stress distribution in the spring. This is done in order to verify the range of validity of design standards. Finite element analysis emerges as a powerful and computationally cheap approach to assess the structural behaviour of Belleville springs regardless of their geometry and level of non-linearity.
Nitric oxide in liver fibrosis: The role of inducible nitric oxide synthase (2015)

The inducible form of nitric oxide synthase (iNOS) is expressed in hepatic cells in pathological conditions. Its induction is involved in the development of liver fibrosis, and thus iNOS could be a therapeutic target for liver fibrosis. This review summarizes the role of iNOS in liver fibrosis, focusing on 1) iNOS biology, 2) iNOS-expressing liver cells, 3) iNOS-related therapeutic strategies, and 4) future directions.
Transcriptional Regulation by Ergosterol in the Yeast <i>Saccharomyces cerevisiae</i> (1996)

Sterol biosynthesis in the yeast Saccharomyces cerevisiae is an energy-expensive, aerobic process, requiring heme and molecular oxygen. Heme, also synthesized exclusively during aerobic growth, not only acts as an enzymatic cofactor but also is directly and indirectly responsible for the transcriptional control of several yeast genes. Because of their biosynthetic similarities, we hypothesized that ergosterol, like heme, may have a regulatory function. Sterols are known to play a structural role in membrane integrity, but regulatory roles have not been characterized. To test possible regulatory roles of sterol, the promoter for the ERG3 gene, encoding the sterol C-5 desaturase, was fused to the bacterial lacZ reporter gene. This construct was placed in strains making aberrant sterols, and the effect of altered sterol composition on gene expression was monitored by beta-galactosidase activity. The absence of ergosterol resulted in a 35-fold increase in the expression of ERG3 as measured by beta-galactosidase activity. The level of ERG3 mRNA was increased as much as ninefold in erg mutant strains or wild-type strains inhibited in ergosterol biosynthesis by antifungal agents. The observed regulatory effects of ergosterol on ERG3 are specific for ergosterol, as several ergosterol derivatives failed to elicit the same controlling effect. These results demonstrate for the first time that ergosterol exerts a regulatory effect on gene transcription in S. cerevisiae.
Activation of antibacterial autophagy by NADPH oxidases (2009)

Autophagy plays an important role in immunity to microbial pathogens. The autophagy system can target bacteria in phagosomes, promoting phagosome maturation and preventing pathogen escape into the cytosol. Recently, Toll-like receptor (TLR) signaling from phagosomes was found to initiate their targeting by the autophagy system, but the mechanism by which TLR signaling activates autophagy is unclear. Here we show that autophagy targeting of phagosomes is not exclusive to those containing TLR ligands. Engagement of either TLRs or the Fcgamma receptors (FcgammaRs) during phagocytosis induced recruitment of the autophagy protein LC3 to phagosomes with similar kinetics. Both receptors are known to activate the NOX2 NADPH oxidase, which plays a central role in microbial killing by phagocytes through the generation of reactive oxygen species (ROS). We found that NOX2-generated ROS are necessary for LC3 recruitment to phagosomes. Antibacterial autophagy in human epithelial cells, which do not express NOX2, was also dependent on ROS generation. These data reveal a coupling of oxidative and nonoxidative killing activities of the NOX2 NADPH oxidase in phagocytes through autophagy. Furthermore, our results suggest a general role for members of the NOX family in regulating autophagy.
Identification of ω-aminotransferase from Caulobacter crescentus and site-directed mutagenesis to broaden substrate specificity. (2008)

A putative aminotransferase gene, cc3143 (aptA), from Caulobacter crescentus was screened by bioinformatical tools and overexpressed in E. coli, and the substrate specificity of the aminotransferase was investigated. AptA showed high activity for short-chain beta-amino acids. It showed the highest activity for 3-amino-n-butyric acid. It showed higher activity toward aromatic amines than aliphatic amines. The 3D model of the aminotransferase was constructed by homology modeling using a dialkylglycine decarboxylase PDB ID: 1DGE) as a template. Then, the aminotransferase was rationally redesigned to increase the activity for 3-amino- 3-phenylpropionic acid. The mutants N285A and V227G increased the relative activity for 3-amino-3-phenylpropionic acid to 3-amino-n-butyric acid by 11-fold and 3-fold, respectively, over that of wild type.
Effects of dietary cholesterol and hypothyroidism on rat apolipoprotein mRNA metabolism. (1987)

The effects of dietary cholesterol and hypothyroidism on the mRNA levels of rat apolipoproteins A-I, A-IV, and E were measured in extracts of rat liver and rat intestine by hybridization to specific cDNA. Four groups, each comprised of six rats, were fed diets consisting of normal laboratory rat chow and either no supplements (control); 5% lard, 1% cholesterol, and 0.3% taurocholic acid (CF); 5% lard, 1% cholesterol, 0.3% taurocholic acid, and 0.1% propylthiouracil (CF-PTU); or 0.1% propylthiouracil (PTU) for 32 days. At the conclusion of the diets, serum cholesterol, triiodothyronine, and thyroxine levels were measured. The average serum cholesterol concentrations for the four groups were 50.4 +/- 3.7, 75.6 +/- 15.3, 135.3 +/- 41.5, and 73.3 +/- 16.4 mg/dl, respectively. The presence of propylthiouracil in the diets significantly lowered triiodothyronine and thyroxine levels in the serum. The mRNA levels for apolipoproteins A-I and A-IV in rat liver decreased significantly after the feeding of the CF-PTU diet (31 +/- 4% and 32 +/- 3% of normal, respectively) and the PTU diet (34 +/- 8% and 43 +/- 12% of normal, respectively), but showed little change after the CF diet (88 +/- 16% and 108 +/- 15% of normal, respectively). The effects of dietary propylthiouracil on the hepatic mRNA levels for apolipoproteins A-I and A-IV imply a role for thyroid hormones in regulating the mRNA levels for these apolipoproteins in rat liver. ApoE mRNA levels in the rat liver decreased slightly after the CF-PTU diet (74 +/- 12% of normal) and after the PTU diet (73 +/- 10% of normal).(ABSTRACT TRUNCATED AT 250 WORDS)
mTOR activation is required for the antidepressant effects of mGluR2/3 blockade (2011)

Recent studies demonstrate that ketamine, a fast-acting antidepressant, rapidly activates the mammalian target of rapamycin (mTOR) and increases synaptogenesis in the prefrontal cortex. Because of the side-effect and abuse potential of ketamine we are investigating alternative agents that produce similar effects. Here, we demonstrate that a single dose of LY 341495, an mGluR₂/₃ antagonist, produces ketamine-like biochemical and behavioural actions. LY 341495 administration rapidly (1 h) activates the mTOR pathway (mTOR, p70S6K, 4E-BP1) and subsequently (24 h later) increases levels of synaptic proteins (PSD-95, GluR1 and Synapsin I), similar to the effects of ketamine. Finally, the antidepressant effects of LY 341495 in the rat forced swim test are completely blocked by the mTOR inhibitor, rapamycin. The results indicate that the antidepressant actions of LY 341495 are mediated by activation of mTOR and suggest that this and other mGluR₂/₃ antagonists could produce rapid antidepressant effects in depressed patients.