gebhart/patrepeval huggingface dataset:
Supramolecular Cyclodextrin Supplements to Improve the Tissue Adhesion Strength of Gelatin Bioglues (2017)

A practical strategy to strengthen the inherent tissue adhesiveness of bioglues was investigated without compromising their chemical structure. A simple blending of α-cyclodextrins (α-CDs) in gelatin glues substantially improved the adhesiveness of the glues upon contact with porcine skin. Interestingly, the adhesiveness was even further enhanced when the glues were supplemented with γ-CDs through the formation of multivalent supramolecular networks inside of the glue. In contrast, the effect of β-CDs was rather limited because their water solubility is relatively low. A model study using modified gold substrates demonstrated that CDs also interacted with biomolecules naturally present in skin, thereby improving the adhesiveness. Altogether, we suggest that the supramolecular networking of CDs, both inside the glue and at the glue-skin interface, could reinforce tissue adhesiveness of bioglues, which allows them to be of great relevance to a primary treatment modality for larger skin incisions.
Disparity-compensated view synthesis for S3D content correction (2012)

The production of stereoscopic 3D HD content is considerably increasing and experience in 2-view acquisition is in progress. High quality material to the audience is required but not always ensured, and correction of the stereo views may be required. This is done via disparity-compensated view synthesis. A robust method has been developed dealing with these acquisition problems that introduce discomfort (e.g hyperdivergence and hyperconvergence...) as well as those ones that may disrupt the correction itself (vertical disparity, color difference between views...). The method has three phases: a preprocessing in order to correct the stereo images and estimate features (e.g. disparity range...) over the sequence. The second (main) phase proceeds then to disparity estimation and view synthesis. Dual disparity estimation based on robust block-matching, discontinuity-preserving filtering, consistency and occlusion handling has been developed. Accurate view synthesis is carried out through disparity compensation. Disparity assessment has been introduced in order to detect and quantify errors. A post-processing deals with these errors as a fallback mode. The paper focuses on disparity estimation and view synthesis of HD images. Quality assessment of synthesized views on a large set of HD video data has proved the effectiveness of our method.
<title>Chemically stregthened Er3+, Nd3+ doped phosphate laser glasses</title> (1995)

Significant enhancement of the thermal loading capability has been achieved with both Er<SUP>3+</SUP> and Nd<SUP>3+</SUP> doped inherently strong glasses by an ion-exchange chemical strengthening process. A free running laser with an average output power of 6.5 W and a Q-switched single mode laser with an energy of 5 mJ at a repetition rate of 15 Hz have been demonstrated at the 1.54 micrometers eye safe wavelength with strengthened QX/Er glass. An average output power of 110 W at 1.05 micrometers has been obtained employing a strengthened QX/Nd glass rod.
<title>Satisfying customer bandwidth demand in IP data networks</title> (2001)

We introduce the notion of customer bandwidth fulfillment in IP data networks and provide a quantitative characterization of the fulfillment using measurements of the router uplink (link connecting a router to the backbone) utilization. The threshold for the uplink utilization is calculated for a given probability of customer fulfillment based on the normal approximation. We use three different stochastic models to prove the normal approximation for the distribution of the uplink utilization. The convergence to the Gaussian diffusion prcess is proved in the framework of the nonstationary exponential Benes buffer model. In a special case of an alternating renewal process, we show that the fulfillment can be evaluated based on measurements of the mean uplink utilization. We also prove that the distribution for the number of busy links in a large generalized Engset model is asymptotically normal that provides another justification of the normal approximation for the uplink utilization. We analyze 5-minutes measurements of the uplink utilization and show that their empirical distribution is close to normal.
A general strategy for highly efficient nanoparticle dispersing agents based on hybrid dendritic linear block copolymers (2009)

Abstract A modular approach to the synthesis of a library of hybrid dendritic‐linear copolymers was developed based on RAFT polymerization from monodisperse dendritic macroRAFT agents. By accurately controlling the molecular weight of the linear block, generation number of the dendrimer and the nature of the dendritic chains ends, the performance of these hybrid block copolymers as dispersing agents was optimized for a range of nanoparticles. For titanium dioxide nanoparticles, dispersion in a poly(methyl methacrylate) matrix was maximized with a second generation dendrimer containing four carboxylic acid end groups, and the quality of dispersion was observed to be superior to commercial dispersing agents for TiO 2 . This approach also allowed novel hybrid dendritic‐linear dispersing agents to be prepared for the dispersion of Au and CdSe nanoparticles based on disulphide and phosphine oxide end groups, respectively. © 2009 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 47: 1237–1258, 2009
A novel method for derivation of Minimal Set of Analytical Redundancy Relations for system diagnosis (2010)

We present a novel concept of Minimal Set of Analytical Redundancy Relation (ARRs) and an efficient method for its calculation for application to system diagnosis. ARRs are one of the crucial tools for model-based diagnosis as well as for optimizing, analyzing, and validating the system of sensors. However, despite the importance of the ARRs for system diagnosis, it seems that less attention has been paid to their efficient application. In this paper, we first discuss the complexity of model-based diagnosis by using ARRs. We then present the concept of Minimal Set of ARRs which enables a faster system diagnosis by significantly reducing the number of ARRs to be evaluated for diagnosis purpose. We then show that the derivation of minimal set of ARRs can be mapped as a 0-1 Integer Programming problem and present an efficient branch-and-bound algorithm for this derivation. We also present the results of application of our method for generating the minimal set of ARRs, to both synthetic and industrial examples, to show the significant reduction in the computational cost that can be achieved for system diagnosis.
Crystal Structure of an Initiation Factor Bound to the 30 <i>S</i> Ribosomal Subunit (2001)

Initiation of translation at the correct position on messenger RNA is essential for accurate protein synthesis. In prokaryotes, this process requires three initiation factors: IF1, IF2, and IF3. Here we report the crystal structure of a complex of IF1 and the 30S ribosomal subunit. Binding of IF1 occludes the ribosomal A site and flips out the functionally important bases A1492 and A1493 from helix 44 of 16S RNA, burying them in pockets in IF1. The binding of IF1 causes long-range changes in the conformation of H44 and leads to movement of the domains of 30S with respect to each other. The structure explains how localized changes at the ribosomal A site lead to global alterations in the conformation of the 30S subunit.
Four-Week, Double-Blind, Placebo- and Ziprasidone-Controlled Trial of Iloperidone in Patients With Acute Exacerbations of Schizophrenia (2008)

Iloperidone is a mixed D2/5-HT2 antagonist in development for treatment of schizophrenia. This trial aimed to evaluate the efficacy and safety of a fixed dose of iloperidone in patients with acute exacerbations of schizophrenia. This randomized, placebo-controlled, multicenter study comprised a 1-week titration period and a 3-week double-blind maintenance period. Eligible patients (n = 593) were randomized to iloperidone 24 mg/d, ziprasidone 160 mg/d as an active control, or placebo. Primary efficacy variable was change from baseline in the Positive and Negative Syndrome Scale Total (PANSS-T) score, using a mixed-effects model repeated measures analysis. Iloperidone demonstrated significant reduction versus placebo on the PANSS-T score (P< 0.01). Significant improvement versus placebo was also demonstrated with ziprasidone (P < 0.05). Compared with ziprasidone, iloperidone was associated with lower rates of many adverse events (AEs) that are particularly troublesome with antipsychotics, including sedation, somnolence, extrapyramidal symptoms, akathisia, agitation, and restlessness; iloperidone was associated with higher rates of weight gain, tachycardia, orthostatic hypotension, dizziness, and nasal congestion as reported as an AE. Most AEs were mild to moderate. A similar amount of QT prolongation was observed with both active treatments, although no patient had a treatment-emergent postbaseline corrected QT interval of 500 msec or greater. The incidence of clinically relevant changes in laboratory parameters was comparable between iloperidone and ziprasidone. Iloperidone was associated with a low incidence of extrapyramidal symptoms. Overall, there was improvement in akathisia with iloperidone treatment. Iloperidone treatment was effective, safe, and well tolerated in patients with acute exacerbation of schizophrenia.
ChemInform Abstract: High‐Temperature Interface Superconductivity Between Metallic and Insulating Copper Oxides. (2008)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A frequency-selective terahertz radiation detector based on a semiconductor superlattice with a resonator (2003)

We propose the new design of the terahertz detector, which must have frequency selection property and operate at room temperature. The idea is based on a standing wave enhancement of detector responsivity. The detector contains lateral semiconductor superlattice, broadband bow tie THz antenna and THz resonator. As compared with well-known variant we change a technology of antenna attachment to the superlattice that allows additionally growing up THz resonator. We performed numerical analyze of the structure based on the relaxation time approximation of electron transport in superlattice and wave line description for matching between antenna and superlattice. We choose the superlattice parameters, which are technically available today and show that the detector responsivity can be enhanced several hundred times in comparison to well known existent variants of a such detector, also the frequency selection quality can achieve a very high value (F/-F/spl sim/10/sup 3/).
A tuneable array of unique steady-state microfluidic gradients (2013)

We report an on-chip gradient generator that has been designed, modelled, fabricated, and characterized to facilitate temporal tuning of several unique gradients in parallel for multiple applications. This design allows for steady state programming of the intensities across multiple orders of magnitude while producing exponential, linear, and logarithmic gradient profiles. The magnitude of the gradients is controlled through regulating the ratio of the two on-chip flow inlets without the need for valves or other active mixers. On-chip binding of biotin by a fluorescent streptavidin complex creates a diffusive barrier that regulates access to the gradient inlets, providing a second orthogonal mechanism for regulating the microgradient intensities. The device is also characterized using an on-chip enzymatic reaction to produce an array of tuneable product concentrations within the various microchannels.
An object-oriented pproject model approach for integrated information system in A/WC industry (1994)

As clients' requests are becoming more diverse and extensive than ever, it is
necessary to concentrate compony whole efforts and to fortify cooperation among
different divisions in the A/E/C industry. In the past development of information
systems, was basic focused on increasing efficency of particular domain tasks, and
was not enough to respond current problems. Therefore, a new method of developing
collaborative and integrated informaton systems is required to synthesize resources in
order to achieve total efficiency. However, it is difficult to generate, share and maintain
project data during the various phases of the A/E/C project life cycle from planning to
design, construction and management of the facility. The project data needs to be
stored, retrieved, manipulated, and updated by many project participants, each with
his/her own view of the information. In order to realize the model description of
an A/E/Cproject, such a project model should support both product-based description
and process-based description. Therefore the author has been proposed an object-
oriented project model (called PMAPM) supporting the multiple views that are required
by various participants in A/E/C pojects, which is very important for integration of the
A/E/C industry.
The scope of this research is to establish an object-oriented project model supporting
multiple views shared by various A/E/C project participants and provide several type
of sub-product model for by computer-based systems using multiple views. The
objective is the eventual development of an integrated system which includes activities
from project planning through design, estimation, construction and facility
management. The object-oriented project model is intended to link CAD systems,
relational databases, knowledge-based expert systems and other conventional software.
This paper describes the development, present status and future directions for
PMAPM, an object-oriented project model designed to facilitate infonnation sharing
along the paths through which workflows between project stages or specialists.
A variational Bayesian model for user intent detection (2014)

Intent detectors in state-of-the-art spoken language understanding systems are often trained with a small number of manually annotated examples collected from the application domain. Search query logs provide a large number of unlabeled queries that would be beneficial to improve such supervised classification. Furthermore, the contents of user queries as well as the clicked URLs provide information about user's intent. In this paper, we propose a variational Bayesian approach for modeling latent intents of user queries and clicked URLs when available. We use this model to enhance supervised intent classification of user queries from conversational interactions. Experiments were run with large volumes of search queries and show significant improvements over state-of-the-art systems.
The Geoclutter Experiment 2001: Remote acoustic imaging of sub-bottom and seafloor geomorphology in continental shelf waters (2002)

In the Geoclutter experiment of April–May 2001, an active sonar system was used to remotely and rapidly image geomorphology over wide areas in continental shelf waters by long-range echo sounding. The bistatic system, deployed in the strataform area south of Long Island, imaged extensive networks of buried river channels and inclined subseafloor strata over tens of kilometers in near real time. Bathymetric relief in the strataform area is extremely benign. The vast majority of features imaged apparently correspond to sub-bottom geomorphology that sound waves reach after tunneling as well as propagating through the overlying sediment. Returns from buried river channels were often found to be as discrete and strong as those from calibrated targets placed in the water column. Since buried river channels are expected to be ubiquitous in continental shelf environments, sub-seafloor geomorphology will play a major role in producing ‘‘false alarms’’ or clutter in long-range sonar systems that search for submerged objects such as underwater vehicles or marine mammals. Wave guide scattering and propagation are inherent to this new remote sensing technology because source signals are transmitted over hundreds of water-column depths in range to image sub-seafloor and seafloor geomorphology.
A Route to Nanoscopic Materials <i>via</i> Sequential Infiltration Synthesis on Block Copolymer Templates (2011)

Sequential infiltration synthesis (SIS), combining stepwise molecular assembly reactions with self-assembled block copolymer (BCP) substrates, provides a new strategy to pattern nanoscopic materials in a controllable way. The selective reaction of a metal precursor with one of the pristine BCP domains is the key step in the SIS process. Here we present a straightforward strategy to selectively modify self-assembled polystyrene-block-poly(methyl methacrylate) (PS-b-PMMA) BCP thin films to enable the SIS of a variety of materials including SiO(2), ZnO, and W. The selective and controlled interaction of trimethyl aluminum with carbonyl groups in the PMMA polymer domains generates Al-CH(3)/Al-OH sites inside the BCP scaffold which can seed the subsequent growth of a diverse range of materials without requiring complex block copolymer design and synthesis.
Method and apparatus for using Doppler modulation parameters for estimation of vibration amplitude (1992)

First Page
A Polariton-Stabilized Spin Clock (2020)

Atom-like quantum systems in solids have been proposed as a compact alternative for atomic clocks, but realizing the potential of solid-state technology will requires an architecture design which overcomes traditional limitations such as magnetic and temperature-induced systematics. Here, we propose a solution to this problem: a `solid-state spin clock' that hybridizes a microwave resonator with a magnetic-field-insensitive spin transition within the ground state of the diamond nitrogen-vacancy center. Detailed numerical and analytical modeling of this `polariton-stabilized' spin clock (PSSC) indicates a potential fractional frequency instability below $10^{-13}$ at 1 second measurement time, assuming present-day experimental parameters. This stability would represent a significant improvement over the state-of-the-art in miniaturized atomic vapor clocks.
High-gain crossed-field amplifier tube (1977)

Raytheon Company, under Naval Electronic Systems Command sponsorship, has conducted a program to develop a high gain crossed-field amplifier. This development program reflected the future needs for high-gain CFA's that would permit lower-powered rf drivers and eliminate the need for high power isolators. Present advantages of the crossed-field amplifier, such as high efficiency and cold cathode operation, were to be retained. The method of obtaining high gain in a crossed-field amplifier was to introduce the rf drive signal at the source of electrons. This was accomplished by forming the secondary emission cathode into a slow-wave structure that will support microwave energy. The traveling wave on the cathode forms the desired space charge spokes at a low energy level. These space charge spokes induce current in the anode circuit. The introduction of rf drive signal onto the cathode also provides a high degree of isolation between the amplified output signal and the rf drive energy. During the present cathode-driven, crossed-field amplifier program, the S-band CFA was operated with an rf gain of 28 dB over a frequency band of 14%. Initial background noise measurements were made using a full 2000 MHz sweep on the spectrum analyzer.
Ventricular Defibrillation With Triphasic Waveforms (2000)

Some 80% tilt triphasic waveforms defibrillate more efficiently than biphasic waveforms with a 300-microF-capacitor defibrillator. The triphasic waveforms for both groups were not superior to 140-microF-capacitor biphasic waveforms. The efficacy of triphasic waveforms depends on phase durations and electrode polarity.
Injectable therapeutic organoids using sacrificial hydrogels (2020)

Abstract Organoids, by promoting self-organization of cells into native-like structures, are becoming widespread in drug-screening technologies, but have so far been used sparingly for cell therapy as current approaches for producing self-organized cell clusters lack scalability or reproducibility in size and cellular organization. We introduce a method of using hydrogels as sacrificial scaffolds, which allow cells to form self-organized clusters followed by gentle release, resulting in highly reproducible multicellular structures on a large scale. We demonstrated this strategy for endothelial cells and mesenchymal stem cells to self-organize into blood-vessel units, which were injected into mice using hypodermic needles, and observed in real time to rapidly form perfusing vasculature. As cell therapy transforms into a new class of therapeutic modality, this simple method – by making use of the dynamic nature of hydrogels – could offer high yields of self-organized multicellular aggregates with reproducible sizes and cellular architectures.
On-Demand Hydrogen via High-Pressure Water Reforming for Military Fuel Cell Applications (2008)

Researchers have developed a high-pressure water-reforming (HPWR) process that produces high-pressure hydrogen from a jet fuel feedstock. Converting petroleum-based fuels to hydrogen for fuel cell use is a unique approach to reducing military petroleum consumption by improving petroleum utilization efficiency. HPWR is an attractive option because, unlike traditional steam methane reforming, it does not require postreformer hydrogen compression and storage. A HPWR apparatus was designed and manufactured. Several catalysts were tested for their ability to produce high-pressure hydrogen from jet fuel. S-8, which is a jet fuel derived from natural gas, was used as a model feedstock for initial experiments because the fuel is sulfur and aromatics free. After optimizing with S-8, JP-8 will be utilized for future experiments. The most promising catalyst produced a 4000psi(gauge) product gas stream that contained 54mol% hydrogen. These experimental results show that HPWR is a promising solution for high-pressure hydrogen production as a key step toward reducing military petroleum use.
Current topics in impedance imaging (1987)

We introduce a definition of 'best' currents to apply to an electrode array on the surface of a body in order to distinguish between the conductivity inside the body and a conjectured conductivity. Using these 'best' currents, we illustrate with a simple example the general fact that a single current applied between a pair of electrodes, loses its ability to distinguish between different conductivities as the size of the region over which the current is applied goes to zero. We next introduce approximations to the best currents on systems having L electrodes, and calculate the ability of these systems to distinguish between conductivities as L goes to infinity and the electrode size goes to zero. We conclude with a simple example that illustrates a process for producing the 'best' currents without a previous knowledge of what is inside the body.