gebhart/patrepeval huggingface dataset:
Building air-infiltration quantification based on sound transmission loss calculated using nearfield acoustic holography (2017)

This talk will demonstrate the abilities of nearfield acoustic holography (NAH) to detect and quantify leakages in building envelopes. A tonal sound source was placed inside a building model which has known leakages and microphone array measurements were obtained from the outside. Equivalent sources model based NAH was applied on the measured data to reconstruct the sound pressure field on the wall of the building model. Present results show that the NAH method was able to successfully locate the major leakages. A single microphone was used to measure the sound pressure level inside the building model which was used as a reference for quantification calculations. The difference between the inner and outer sound pressure levels was related to the area of the leakage. Various sizes of pinholes and rectangular cracks were investigated, and the detection limits of the current method were explored.
A vacuum field effect transistor using silicon field emitter arrays (1986)

In this paper we will present results taken from the first planar silicon field emitter array vacuum "field effect transistor". This new device structure replaces the solid channel region of a standard silicon FET with the vacuum. The "source" consists of an array of micron size silicon field emitters from which carriers are injected into the "channel" vacuum region. Gate modulation of this new device structure has produced both voltage and power gain.
DEVELOPMENT OF HUMASORBtm--A COAL DERIVED HUMIC ACID FOR REMOVAL OF METALS AND ORGANIC CONTAMINANTS FROM GROUNDWATER (2000)

No abstract prepared.
Transmission blockage of an orthotospovirus using synthetic peptides (2019)

Orthotospoviruses are acquired by thrips during feeding on infected tissue. Virions travel through the foregut and enter midgut epithelial cells through the interaction between the viral glycoproteins and cellular receptors. Glycoprotein RGD motifs and N-linked glycosylation sites have been predicted to mediate receptor binding or play important roles in virus entry into host cells, yet their function needs to be validated. In this study, peptides derived from the soybean vein necrosis virus N glycoprotein were utilized to identify critical regions in virus-vector interactions. Transmission mediated by single <i>Neohydatothrips variabilis</i> dropped by more than 2/3 when thrips were fed on peptide NASIAAAHEVSQE or the combination of NASIRGDHEVSQE and RLTGECNITKVSLTN when compared to the controls; indicating that this strategy could significantly reduce transmission efficiency, opening new avenues in the control of diseases caused by orthotospoviruses.
First synthesis of a fully active spin‐labeled peptide hormone<sup>1</sup> (1999)

For the first time in the electron spin resonance (ESR) and peptide synthesis fields, a fully active spin-labeled peptide hormone was reported. The ESR spectra of this alpha-melanocyte stimulating hormone (alpha-MSH) analogue (acetyl-Toac0-alpha-MSH) where Toac is the paramagnetic amino acid probe 2,2,6,6-tetramethylpiperidine-1-oxyl-4-amino-4-carboxylic acid, suggested a pH-independent conformation and a more restricted movement comparatively to the free Toac. Owing to its equivalent biological potency in a skin pigmentation assay as compared to the native alpha-MSH and its unique characteristic (paramagnetic, naturally fluorescent and fully active), this analogue is of great potential for investigation of relevant physiological roles reported for alpha-MSH.
Role of CCR5 in the Pathogenesis of IL-13-Induced Inflammation and Remodeling (2006)

IL-13 is a major effector at sites of Th2 inflammation and tissue remodeling. In these locations, it frequently coexists with the CCR5 chemokine receptor and its ligands MIP-1alpha/CCL3 and MIP-1beta/CCL4. We hypothesized that CCR5 induction and activation play important roles in the pathogenesis of IL-13-induced tissue responses. To test this hypothesis, we evaluated the effects of IL-13 on the expression of CCR5 in the murine lung. We also compared the effects of lung-targeted transgenic IL-13 in mice treated with anti-CCR5 or an Ab control and mice with wild-type or null CCR5 loci. These studies demonstrate that IL-13 is a potent stimulator of epithelial cell CCR5 expression. They also demonstrate that CCR5 neutralization or a deficiency of CCR5 significantly decreases IL-13-induced inflammation, alveolar remodeling, structural and inflammatory cell apoptosis, and respiratory failure and death. Lastly, these studies provide mechanistic insights by demonstrating that CCR5 is required for optimal IL-13 stimulation of select chemokines (MIP-1alpha/CCL3, MIP-1beta/CCL4, MCP-1/CCL-2), matrix metalloproteinase-9 and cell death regulators (Fas, TNF, TNFR1, TNFR2, Bid), optimal IL-13 inhibition of alpha1-antitrypsin, and IL-13-induction of and activation of caspases-3, -8, and-9. Collectively, these studies demonstrate that CCR5 plays a critical role in the pathogenesis of IL-13-induced inflammation and tissue remodeling.
DUAL SITE CATALYSTS FOR HYDRIDE MANIPULATION (2011)

This comment describes our efforts to develop dual site catalysts for hydride manipulation. We began by analyzing the mechanism of alcohol oxidation with the ruthenium-based Shvo catalyst, which utilizes a proton transfer to template a hydride transfer from carbon to ruthenium in a single transition state. In our project we are working to extend this concept of reactivity from the use of proton transfer as a templating interaction for hydride transfer to the use of a Lewis acid to coordinate and direct a substrate to a metal. Along these lines, we have found that ammonia borane, a popular and high-weight-content hydrogen storage material, has been one of our best model substrates with which to study hydride transfer mechanisms. Our ongoing studies have thus far given new insight into the reactivity of the Shvo system, particularly regarding dehydrogenation of ammonia borane, and have enabled us to design a new, prolific, air- and water-tolerant, and reusable catalyst for ammonia borane dehydrogenation.
Transducer Joint for Kidney-Stone Ultrasonics (1983)

Ultrasonic therapy for kidney stones improved by new way of connecting wire-probe ultrasonic waveguide to transducer. Improved mounting allows joint to last long enough for effective treatment. Sheath and rubber dampers constrain lateral vibration of wire waveguide. Combination of V-shaped mounting groove, sheath, and rubber dampers increases life expectancy of wire 15 times or more.
Application of Free Form Reflectors in Modern Headlamp Systems (1995)

<div class="htmlview paragraph">Car Designers are asking more often for headlamps that adapt well to highly inclined and low vehicle bodies or other exotic shapes e. g. of sports cars. In other cases headlamps are additionally used as stylistic elements and must therefore have a certain appearance e. g. oval shape or a clear, unprofiled cover glass. To realize a headlamp for such applications and at the same time keep it cost-effective with good light quality special headlamp systems have to be developed. Especially the normally used profiled scattering lens in front of the reflector causes complications under these circumstances. Therefore headlamp systems with complex reflector shapes have been developed whose reflectors produce an almost complete light distribution. Some different reflector concepts to realize this idea are presented in this paper and concrete examples for the application of this new technique are discussed.</div>
Role of Acidic Sphingomyelinase in Fas/CD95-mediated Cell Death (2000)

Engagement of the Fas receptor has been reported to induce ceramide generation via activation of acidic sphingomyelinase (aSMase). However, the role of aSMase in Fas-mediated cell death is controversial. Using genetically engineered mice deficient in the aSMase gene (aSMase(-/-)), we found that thymocytes, concanavalin A-activated T cells, and lipopolysaccharide-activated B cells derived from both aSMase(-/-) and aSMase(+/+) mice were equally sensitive to Fas-mediated cell death, triggered by either anti-Fas antibody or Fas ligand in vitro. Similarly, activation-induced apoptosis of T lymphocytes was unaffected by the status of aSMase, and aSMase(-/-) mice failed to show immunological symptoms seen in animals with defects in Fas function. In vivo, intravenous injection of 3 microg/25 g mouse body weight of anti-Fas Jo2 antibody into aSMase(-/-) mice failed to affect hepatocyte apoptosis or mortality, whereas massive hepatocyte apoptosis and animal death occurred in wild type littermates. Animals heterozygous for aSMase deficiency were also significantly protected. Susceptibility of aSMase(-/-) mice to anti-Fas antibody was demonstrated with higher antibody doses (>/=4 microg/25 g mouse). These data indicate a role for aSMase in Fas-mediated cell death in some but not all tissues.
Toward a solid-state, compact, terahertz-wave radar (2019)

We report the principle and first experimental results on a terahertz-wave radar based on a resonant-tunneling diode (RTD) working as a 522 GHz radiation source and a Schottky barrier diode (SBD) as a detector. By modulating the output power of the RTD at two frequencies and measuring the corresponding phase delays after the terahertz wave propagates from the source to the detector, we were able to measure the absolute propagation distance between them (including all the cables carrying the signals) with an error of about 10 mm. We then combined this absolute distance with the phase delay measured at one frequency to further reduce the error of the distance measurement to below 0.4 mm.
Near-Field Scanning Optical Imaging with Monolithic Silicon Light Emitting Diode on Probe Tip (2008)

We describe optical and topographic imaging using a light emitting diode (LED) monolithically integrated on a silicon probe tip for near-field scanning optical microscopy (NSOM). The light emission resulted from a silicon dioxide layer buried between a phosphorus-doped N+ silicon layer and a gallium-doped P+ silicon region created locally at the tip by a focused ion beam (FIB). The tip was employed in a standard NSOM excitation setup. The probe successfully measured optical as well as topographic images of a chromium test pattern with imaging resolutions of 400 nm and 50 nm, respectively. The directional resolution dependence of the acquired images directly corresponds to the shape, size and polarity of the light source on the probe tip. To our knowledge, this report is the first successful near-field imaging result directly measured by such tip-embedded light sources.
In vitro measurements of physiological glucose concentrations in biological fluids using mid-infrared light (2013)

Mid-infrared transmission spectroscopy using broadband mid-infrared or Quantum Cascade laser sources is used to predict glucose concentrations of aqueous and serum solutions containing physiologically relevant amounts of glucose (50-400 mg/dL). We employ partial least squares regression to generate a calibration model using a subset of the spectra taken and to predict concentrations from new spectra. Clinically accurate measurements with respect to a Clarke error grid were made for concentrations as low as 30 mg/dL, regardless of background solvent. These results are an important and encouraging step in the work towards developing a noninvasive in vivo glucose sensor in the mid-infrared.
1028 nm single mode Ytterbium-doped fiber laser (2009)

An efficient Ytterbium-doped fiber laser (YDFL) operating at 1028 nm is demonstrated using a fiber Bragg grating (FBG). The Ytterbium-doped fiber (YDF) is drawn from Yb2O3-doped preform, fabricated through deposition of porous layer of composition SiO2-GeO2 by the MCVD process in conjunction with a solution doping technique. The fabricated YDF has a 0.1 mol % of Yb2O3 in the core, a Ytterbium ion lifetime of 1.1 ms, an absorption of 7.65 dB/m at 976 nm. The fiber laser has the maximum efficiency of 51% with pump power threshold of 19 mW using a FBG in conjunction with a Fresnel reflection to form a linear cavity resonator. The efficiency and threshold are better compared to the similar YDFL configuration using a commercial YDF.
Identification of bacteria using linear programmed thermal degradation mass spectrometry. The preliminary investigation (1976)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIdentification of bacteria using linear programmed thermal degradation mass spectrometry. The preliminary investigationTerence H. Risby and Alfred L. YergeyCite this: J. Phys. Chem. 1976, 80, 26, 2839–2845Publication Date (Print):December 1, 1976Publication History Published online1 May 2002Published inissue 1 December 1976https://doi.org/10.1021/j100567a006RIGHTS & PERMISSIONSArticle Views42Altmetric-Citations29LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (714 KB) Get e-Alerts
Heterologous prime-boost strategy in non-human primates combining the infective dengue virus and a recombinant protein in a formulation suitable for human use (2009)

The results obtained in the present work support the approach of heterologous prime-boosting, in either order prime or boost, combining the chimeric protein PD5 (formulated in alum-CPS-A) and an infective dengue virus. The latter could potentially be replaced by an attenuated vaccine candidate.
Pressure, temperature, and product yield relationships in direct oxidative methane conversion at elevated pressures and moderate temperatures (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPressure, temperature, and product yield relationships in direct oxidative methane conversion at elevated pressures and moderate temperaturesDennis E. Walsh, Daniel J. Martenak, Scott Han, Robert E. Palermo, James N. Michaels, and David L. SternCite this: Ind. Eng. Chem. Res. 1992, 31, 11, 2422–2425Publication Date (Print):November 1, 1992Publication History Published online1 May 2002Published inissue 1 November 1992https://pubs.acs.org/doi/10.1021/ie00011a003https://doi.org/10.1021/ie00011a003research-articleACS PublicationsRequest reuse permissionsArticle Views241Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Optoelectronic switch based on intrinsic dual Schottky diodes in ambipolar MoSe$_2$ field-effect transistors (2015)

Here, we report the observation of a hitherto unreported optoelectronic effect, namely a light-induced diode-like response in multi-layered MoSe$_2$ field-effect transistors whose sense of current rectification is controllable through a gate voltage. We argue, through numerical simulations, that this behavior results from the difference in the size of the Schottky barriers between drain and source metal contacts. Each barrier can be modeled as a Schottky diode but with opposite senses of current rectification between them, with the diode response resulting from the light induced promotion of photo-generated carriers across the smaller barrier. The back gate voltage controls the sense of current rectification by modulating the relative amplitude between them. This effect, which gives rise to a novel type of optoelectronic switch, also yields a photovoltaic response. Hence, it could provide an alternative to PN-junctions when harvesting photovoltaic currents from transition metal dichalcogenides. We argue that the photovoltaic efficiency associated to this effect could be increased by just increasing the relative asymmetry between both Schottky barriers. We also suggest that this new electro-optical effect has potential for technological applications.
Complex of transferrin with ruthenium for medical applications. [Ru 97, Ru 103] (1980)

A novel Ruthenium-transferrin complex, prepared by reacting iron-free human transferrin dissolved in a sodium acetate solution at pH 7 with ruthenium by heating at about 40/sup 0/C for about 2 hours, and purifying said complex by means of gel chromatography with pH 7 sodium acetate as eluent. The mono- or di-metal complex produced can be used in nuclear medicine in the diagnosis and/or treatment of tumors and abscesses. Comparitive results with Ga-67-citrate, which is the most widely used tumor-localizing agent in nuclear medicine, indicate increased sensitivity of detection and greater tumor uptake with the Ru-transferrin complex.
Contrasting photovoltaic response and photoluminescence for distinct porous silicon pore structures (2000)

The photoluminescent (PL) emission and photovoltaic (PV) response of two distinctly structured (prepared) porous silicon (PS) surfaces are compared and contrasted. The PV response of a porous silicon structure consisting of a microporous framework on which is superimposed a nanoporous layer is distinct from that of the branched nanoporous silicon structure generated in an aqueous etch environment. The observed PV response for this hybrid morphology is clearly not dominated by the covering nanoporous structure and displays a response that appears to be intermediate between those observed for nanoporous PS (band gap 1.80\ifmmode\pm\else\textpm\fi{}0.2 eV) and crystalline silicon. In contrast, time-dependent histograms of the PL emission from the hybrid microporous-nanoporous and nanoporous structures, although not precisely the same, are quite similar. These observations, while consistent with a surface-dominated emission process associated with a bound fluorophor and not with the quantum confinement model, do suggest the influence of the PS bulk morphology on surface transformation.
Poly (p-phenyleneacetylene) light-emitting diodes (1994)

Acetylene containing poly(p-phenyleneacetylene) (PPA) - based light-emitting diodes (LEDs) are provided. The LEDs are fabricated by coating a hole-injecting electrode, preferably an indium tin oxide (ITO) coated glass substrate, with a PPA polymer, such as a 2,5-dibutoxy or a 2,5-dihexoxy derivative of PPA, dissolved in an organic solvent. This is then followed by evaporating a layer of material capable of injecting electrons, such as Al or Al/Ca, onto the polymer to form a base electrode. This composition is then annealed to form efficient EL diodes. 8 figs.
Human Neuropeptide Y1 Receptor Expressed in <i>Escherichia coli</i> Retains Its Pharmacological Properties (1994)

The coding region of the gene for the human neuropeptide Y (NPY) Y1 receptor was fused to the maltose binding protein gene. Expression of this transcription unit, after derepression with isopropyl beta-D-thiogalactopyranoside, was evidenced by the appearance of a protein of higher molecular weight, as well as the native maltose binding protein, both of which were immunoreactive with anti-maltose binding protein antibodies. Specific [125I]NPY binding activity was found associated mainly with the inner bacterial membrane fraction, suggesting that the receptor is correctly folded in this membrane. Competition binding experiments using NPY Y1- and Y2-specific ligands clearly exhibited a NPY Y1 specific pharmacological profile with Kd values indistinguishable from those of the native receptor. These results suggest that the membrane environment required by the human NPY Y1 receptor for specific high-affinity ligand binding is conserved in this heterologous bacterial system and can be used for detailed analyses of ligand-receptor interaction and drug screening.
Linkage analysis and comparative mapping of canine progressive rod–cone degeneration ( <i>prcd</i> ) establishes potential locus homology with retinitis pigmentosa (RP17) in humans (1998)

Progressive rod-cone degeneration (prcd) is the most widespread hereditary retinal disease leading to blindness in dogs and phenotypically is the canine counterpart of retinitis pigmentosa (RP) in humans. In previous efforts to identify the genetic locus for prcd, the canine homologs for many of the genes causally associated with RP in humans, such as RHO, PDE6B, and RDS/peripherin, have been excluded. In parallel with a recent undertaking to establish a framework map of the canine genome, multiple prcd-informative pedigrees have been typed with a panel of more than 100 anchor loci and microsatellite-based markers. Identification of a linkage group flanking prcd ([TK1, GALK1, prcd]-[MYL4, C09.173, C09.2263]-RARA-C09.250-C09.474-NF1) localizes prcd close to the centromeric end of canine chromosome 9 (CFA9), and excludes RARA as a candidate gene. The conserved synteny of this region of CFA9 and distal human chromosome 17q establishes the potential locus homology of prcd in the dog with RP17, a human retinitis pigmentosa locus for which no gene has yet been identified. Assignment of the prcd disease locus to an identified canine autosome represents a powerful application of the developing canine linkage map in medical genetics. The usefulness of this approach is further demonstrated by identification of the correspondence of the prcd interval to homologous human and mouse chromosomal regions. The rapid progress that is now occurring in the field of canine genetics will expedite the identification of the genes underlying many of the inherited traits and diseases that make the dog a unique asset for the study of mammalian traits.