gebhart/patrepeval huggingface dataset:
Concurrent Modulation of Quantum Dot Photoluminescence Using a Combination of Charge Transfer and Förster Resonance Energy Transfer: Competitive Quenching and Multiplexed Biosensing Modality (2016)

An emerging trend with semiconductor quantum dots (QDs) is their use as scaffolds to assemble multiple energy transfer pathways. Examples to date have combined various competitive and sequential Förster resonance energy transfer (FRET) pathways between QDs and fluorescent dyes, luminescent lanthanide complexes, and bioluminescent proteins. Here, we show that the photoluminescence (PL) of QD bioconjugates can also be modulated by a combination of FRET and charge transfer (CT), and characterize the concurrent effects of these mechanistically different pathways using PL measurements at both the ensemble and the single particle level. Peptides were distally labeled with either a fluorescent dye that quenched QD PL through FRET or a ruthenium(II) phenanthroline complex that quenched QD PL through electron transfer. The labeled peptides were assembled around a central CdSe/ZnS QD at different ratios, tuning the relative rates of FRET and CT, which were competitive quenching pathways. The concurrent effects of FRET and CT were predictable from a rate analysis that was calibrated to the isolated effects of each of these pathways. Notably, the dye/QD PL intensity ratio reflected changes in the relative rate of FRET but was approximately independent of CT. In turn, the sum of the QD and dye PL intensities, when adjusted for quantum yields, reflected changes in the relative rate of CT quenching, approximately independent of FRET. The capacity for multiplexed sensing of protease activity was demonstrated using these two orthogonal detection channels. Combined CT-FRET configurations with QDs are thus promising for applications in bioanalysis, sensing, and imaging, and may prove useful in other photonic applications.
Organo clay assemblies for triphase catalysis (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOrgano clay assemblies for triphase catalysisChi Li Lin and Thomas J. PinnavaiaCite this: Chem. Mater. 1991, 3, 2, 213–215Publication Date (Print):March 1, 1991Publication History Published online1 May 2002Published inissue 1 March 1991https://pubs.acs.org/doi/10.1021/cm00014a003https://doi.org/10.1021/cm00014a003research-articleACS PublicationsRequest reuse permissionsArticle Views129Altmetric-Citations28LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Fatty acid derivatives. omega. -substituted with a neutral technetium complex (1985)

The clinical importance of noninvasive probes of myocardial metabolism continues to promote investigation into the preparation of radiolabeled fatty acid derivatives useful for diagnostic imaging. The preparation of such compounds labeled with Tc-99m remains a major goal. Based on previous investigations of oxotechnetium(+5) bisamido bisthiolato (N/sub 2/S/sub 2/) complexes, the authors now report the synthesis of a series of ligands designed to form stable neutral technetium complexes whilst retaining the essential characteristics of a fatty acid. The design allows both for the incorporation of diverse fatty acid fragments and for metabolism of these fragments to produce a small readily excretable technetium complex as the final labeled metabolite. The first of these ligands, N,N'-ethylenebis-(2-mercapto)(2'-(11-carboxyundecyl)thio)acetamide, undergoes ligand exchange with Tc-99-(TcO(ethanediolato)2)/sup -/ to form a stable neutral lipophilic oxotechnetium(+5) complex as a diastereomeric pair of enantiomers. One pair of enantiomers has been characterized by elemental analysis, by its /sup 1/H and /sup 13/C NMR, IR, and UV spectra, and by fast-atom bombardment spectrometry. All data are consistent with the formulation: oxo(N,N'-ethylenebis- (2-mercapto)(2'-(11-carboxyundecyl)thio)acetamido)-technetium(+5). This complex can also be prepared at the tracer level by ligand exchange with Tc-99m-glucoheptonate. The Tc-99 and Tc-99m complexes co-elute on reverse-phase HPLC.
Compact DC Josephson Voltage Standard (2020)

This paper presents precision measurements with a prototype cryogen-liquid-free DC Josephson voltage standard that produces a 1 V maximum output. Its cryostat is sufficiently compact that it can be operated on a bench close to devices under test. Compared to the National Institute of Standards and Technology (NIST) programmable Josephson voltage standard (PJVS), this bench-top Josephson voltage standard (BJVS) has a smaller cryostat (only 25 % of the volume), the Josephson junction array circuit is less complex and has only 10 % as many junctions, simpler bias electronics, and reduced mechanical cooling requirements. Direct voltage comparison between the BJVS and the PJVS achieved a relative agreement of 5×10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-10</sup> at 1 V. With the recent redefinition of the International System of Units (SI), the BJVS becomes a primary realization the unit volt, requiring only access to a standard single-phase power outlet and a GPS signal (SI second).
Electronics package with improved thermal management by thermoacoustic heat pumping (1994)

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Feedback Channel Capacity Inspired Optimum Signal Constellation Design for High-Speed Optical Transmission (2012)

In this paper, we describe a feedback channel capacity inspired optimum signal constellation design (FCC-OSCD), for channel capacity achieving source distribution. The constellations obtained by FCC-OSCD are OSNR dependent. We demonstrate by Monte Carlo simulations that 32-ary signal constellation, obtained by FCC-OSCD, outperforms previously proposed optimized 32-ary signal constellation by 1.2 dB at BER of 10−7.
Amino-oxyacetic Acid as a Palliative in Tinnitus (1985)

Amino-oxyacetic acid, previously shown to cause a reversible loss of hearing sensitivity and a reduction in endocochlear potential, was tried as a palliative in human tinnitus. Because the drug seemed to have a cochlear site of action, patients were selected for the study if their audiograms were indicative of cochlear lesions and if there was a reduction in tinnitus following intravenous lidocaine (lidocaine positive). Ten such patients received either 50 or 75 mg of amino-oxyacetic acid four times a day orally for one week or placebo administered in a random, crossover, double-blind design. Of these ten, three reported subjective lessening of tinnitus. One of those three and two others not reporting subjective lessening of tinnitus showed a substantial improvement in speech discrimination scores while receiving amino-oxyacetic acid but not placebo. One additional patient who did not receive lidocaine also reported a subjective lessening of tinnitus. Four patients who were lidocaine negative showed neither subjective nor objective improvement in tinnitus after treatment with amino-oxyacetic acid.
Measurement Range Elongation Based on Temporal Gating in Brillouin Optical Correlation Domain Distributed Simultaneous Sensing of Strain and Temperature (2012)

We had earlier demonstrated the distributed discrimination of strain and temperature by localizing and scanning both the stimulated Brillouin scattering and the Brillouin dynamic grating along a polarization-maintaining fiber. The localization and scanning were performed by a correlation domain technique, whose measurement range was restricted by the distance between consecutive correlation peaks. To overcome this restriction, in this letter, we apply a temporal gating scheme to the system by enlarging the measurement range from ~25 to ~500 m. We report the results confirming the effectiveness of this scheme in a system operated by a single laser source, and demonstrate the strain-temperature discrimination when strain or temperature is applied to segments on the 500-m-long fiber under test.
Multilayer Enhanced Gold Film over Nanostructure Surface-Enhanced Raman Substrates (2006)

We have developed a novel class of gold multilayer, surface-enhanced Raman scattering (SERS) substrates that are capable of enhancing SERS signals by 15.3-fold over conventional gold film over nanostructure (GFON) SERS substrates, making them comparable in sensitivity to optimized silver film over nanostructure (SFON) substrates, while providing the long-term stability obtained from gold. They are fabricated by depositing 10 A thick silver oxide islands on conventional GFON substrates, followed by deposition of a second continuous gold layer. The silver oxide layer acts as a dielectric spacer between the two continuous gold films and produces significantly enhanced SERS signals, as compared to optimized single layer substrates of the same geometry or comparable substrates prepared by deposition of silver islands that are not oxidized. In addition to the enhanced sensitivity of these multilayer substrates, they also exhibit long SERS active shelf-lives (i.e., months), with no measurable degradation in SERS enhancement, and relative standard deviations in SERS enhancement of less than 5.2% across the substrate's surface.
NbTi wires with ultra-fine filaments for 50 - 60 Hz use: Influence of the filament diameter upon losses (1985)

For eighteen months, we have manufactured long lengths of multifilamentary superconducting wires, which comprise from several ten thousand to several hundred thousand 0.08 to 1 micron-diameter NbTi filaments. In these wires, the matrix between the filaments is made of pure CuNi and their structure provides a good magnetic stability and leads to strongly reduced 50 Hertz losses. Obtained results open very new prospects for applications of superconductivity in fast pulsed magnets and in A.C. current devices. In this paper we present results of 50 Hz loss measurements in these wires and we discuss the influence of the filament diameter upon these losses.
Optimized Compilation of Aggregated Instructions for Realistic Quantum Computers (2019)

Recent developments in engineering and algorithms have made real-world applications in quantum computing possible in the near future. Existing quantum programming languages and compilers use a quantum assembly language composed of 1- and 2-qubit (quantum bit) gates. Quantum compiler frameworks translate this quantum assembly to electric signals (called control pulses) that implement the specified computation on specific physical devices. However, there is a mismatch between the operations defined by the 1- and 2-qubit logical ISA and their underlying physical implementation, so the current practice of directly translating logical instructions into control pulses results in inefficient, high-latency programs. To address this inefficiency, we propose a universal quantum compilation methodology that aggregates multiple logical operations into larger units that manipulate up to 10 qubits at a time. Our methodology then optimizes these aggregates by (1) finding commutative intermediate operations that result in more efficient schedules and (2) creating custom control pulses optimized for the aggregate (instead of individual 1- and 2-qubit operations). Compared to the standard gate-based compilation, the proposed approach realizes a deeper vertical integration of high-level quantum software and low-level, physical quantum hardware. We evaluate our approach on important near-term quantum applications on simulations of superconducting quantum architectures. Our proposed approach provides a mean speedup of $5\times$, with a maximum of $10\times$. Because latency directly affects the feasibility of quantum computation, our results not only improve performance but also have the potential to enable quantum computation sooner than otherwise possible.
Evidence for a CD38+ active subset enriched in proliferating cells, within the clonal population in chronic lymphocytic leukemia patients (2007)

LB-340 Historically, chronic lymphocytic leukemia (B-CLL) is known as a lymphoid neoplasm characterized by the accumulation of CD5+ B cells showing morphologic features of resting cells. In the last decade several studies have revealed the existence of at least two clinically distinct subgroups among B-CLL cases. These cases can be distinguished by the existence of somatic mutations in Ig V genes and by their expression of cell activation markers such as CD38 and ZAP-70, which have now achieved prognostic significance. To assess which aspects of the immunobiology of B-CLL cells are impacted by expression of CD38 by clonal members within a B-CLL case we flow-sorted B-CLL cells from peripheral blood of 20 patients (% CD38 expression pre-sort, ranging from 1- 90%), into CD38- and CD38+ subsets and quantified telomere lengths as a measure of their replicative history. As a measure of cellular activation we studied telomerase activity in these flow-sorted cells. In addition, expression of activation-associated (CD27, CD69 and CD62L), signaling-associated (ZAP-70) and cell cycle-associated (Ki-67) markers were studied on CD38- and CD38+ cell subsets by immunofluorecence and multi-color flow cytometry in 95 cases (including those used for cell sorting experiments). Telomerase activity was markedly higher in the CD38+ subset compared to the CD38- subset in each case (p
Sgs-Thomson Dsp D950-Core Audio Compression (1996)

Publication in the conference proceedings of EUSIPCO, Trieste, Italy, 1996
Free form optical system design with differential equations (2010)

The general Wassermann-Wolf differential equations were derived to design an off-axis free form surface (FFS) prism head mounted display (HMD) system. A FFS prism HMD system with 20° degree, 8mm exit pupil and 15mm-effective focal length was designed and the image qualities were analyzed.
Evaluation of posterior porcine sclera elasticity in situ as a function of IOP (2018)

The biomechanical properties of the sclera could provide key information regarding the progression and etiology of ocular diseases. For example, an elevated intraocular pressure is one of the most common risk factors for glaucoma and can cause pathological deformations in the tissues of the posterior eye, such as the sclera, potentially damaging these vital tissues. Previous work has evaluated scleral biomechanical response to global displacements with techniques such as inflation testing. However, these methods cannot provide localized biomechanical assessments. In this pilot work, we induce low amplitude (< 10 μm) elastic waves using acoustic radiation force in posterior scleral tissue of fresh porcine eyes (n=2) in situ. The wave propagation induced using an ultrasound transducer was detected across an 8 mm region using a phase-sensitive optical coherence elastography system (PhS-OCE). The elastographic measurements were taken at various artificially controlled intraocular pressures (IOP). The IOP was pre-cycled before being set to 10 mmHg for the first measurement. Subsequent measurements were taken at 20 mmHg and 30 mmHg for each sample. The results show an increase in the stiffness of the sclera as a function of IOP. Furthermore, we observed a variation in the elasticity based on direction, suggesting that the sclera has anisotropic biomechanical properties. Our results show that OCE is an effective method for evaluating the mechanical properties of the sclera, and reveals a new area for our future work.
FUSE: lightweight guaranteed distributed failure notification (2004)

FUSE is a lightweight failure notification service for building distributed systems. Distributed systems built with FUSE are guaranteed that failure notifications never fail. Whenever a failure notification is triggered, all live members of the FUSE group will hear a notification within a bounded period of time, irrespective of node or communication failures. In contrast to previous work on failure detection, the responsibility for deciding that afailure has occurred is shared between the FUSE service and the distributed application. This allows applications to implement their own definitions of failure. Our experience building a scalable distributed event delivery system on an overlay network has convinced us of the usefulness of this service. Our results demonstrate that the network costs of each FUSE group can be small; in particular, our overlay network implementation requires no additional liveness-verifying ping traffic beyond that already needed to maintain the overlay, making the steady state network load independent of the number of active FUSE groups.
Client Clustering for Hiring Modeling in Work Marketplaces (2015)

An important problem that online work marketplaces face is grouping clients into clusters, so that in each cluster clients are similar with respect to their hiring criteria. Such a separation allows the marketplace to "learn" more accurately the hiring criteria in each cluster and recommend the right contractor to each client, for a successful collaboration. We propose a Maximum Likelihood definition of the "optimal" client clustering along with an efficient Expectation-Maximization clustering algorithm that can be applied in large marketplaces. Our results on the job hirings at oDesk over a seven-month period show that our client-clustering approach yields significant gains compared to "learning" the same hiring criteria for all clients. In addition, we analyze the clustering results to find interesting differences between the hiring criteria in the different groups of clients.
Alternating current operation of the dual-input fiber-optic gyroscope (1981)

Fiber-optic Sagnac interferometers1 are under active investigation for passive gyroscope applications. Two problems associated with the conventional configuration are its sensitivity minimum at zero rotation rate and the effect of noise sources on its intrinsic dc operation. Recently several schemes to operate the Sagnac interferometer at maximum sensitivity (in quadrature) have been demonstrated.2,3
Optimization of the Bass Management Filter Parameters for Multichannel Audio Applications (2006)

Traditionally, room acoustic equalization is performed to improve sound quality in an environment. In a multi-channel audio system employing room equalization, the selection of the bass management filter parameters, such as the crossover frequency and the decay rate for the subwoofer and satellite, is important for accurate reproduction of playback sound. Presently, many systems (e.g., home-theater receivers) have selectable crossover frequencies with fixed decay rates. A poor choice of the crossover frequency and decay rates can result in undesirable interactions, in the subwoofer-satellite net response, even after equalization. Such interactions, due to complex addition (i.e., phase and amplitude) of the subwoofer and satellite response, manifests as a broad notch in the net magnitude response which in turn leads to a loss of sound output in the crossover frequency region. In this paper, we present an automatic method for selecting the bass management filter parameters, based on an objective measure, for multi-channel audio applications. The proposed method allows better control of the resulting subwoofer-satellite response, around the crossover region, thereby significantly improving audio quality
Specular Reflection Separation Using Dark Channel Prior (2013)

We present a novel method to separate specular reflection from a single image. Separating an image into diffuse and specular components is an ill-posed problem due to lack of observations. Existing methods rely on a specular-free image to detect and estimate specularity, which however may confuse diffuse pixels with the same hue but a different saturation value as specular pixels. Our method is based on a novel observation that for most natural images the dark channel can provide an approximate specular-free image. We also propose a maximum a posteriori formulation which robustly recovers the specular reflection and chromaticity despite of the hue-saturation ambiguity. We demonstrate the effectiveness of the proposed algorithm on real and synthetic examples. Experimental results show that our method significantly outperforms the state-of-the-art methods in separating specular reflection.
A Sensorless Rotational Speed-Based Control System for Continuous Flow Left Ventricular Assist Devices (2019)

Maintaining a constant differential pump speed can simultaneously achieve physiologic perfusion and suction prevention without needing unreliable, direct measurements of flow or pressure, or complex parameter or model-based estimation techniques.
Slotted Aloha-NOMA with MIMO Beamforming for Massive M2M Communication in IoT Networks (2018)

This paper proposes an uncoordinated random medium access protocol for Internet of Thing (IoT) networks incorporating conventional slotted Aloha (SA) with power domain non-orthogonal multiple access (PD-NOMA) and multiple-input multiple-output beamforming (MIMO BF). The number of active IoT devices, which is not known a priori, is detected at the IoT gateway via multiple hypothesis testing. The proposed protocol referred to as BF-SA-NOMA is not only scalable and compatible with the power-limited IoT devices, but it also uses beamforming to significantly improve the throughput to 1.31 compared with 0.36 in conventional slotted Aloha when 6 active IoT devices can be successfully separated using 2×2 MIMO and a SIC (Successive Interference Cancellation) receiver with 3 optimum power levels. The simulation results further show that the proposed protocol achieves higher throughput than Aloha-NOMA with a lower average channel access delay.
Design of a biomimetic robotic octopus arm (2009)

This paper reports the rationale and design of a robotic arm, as inspired by an octopus arm. The octopus arm shows peculiar features, such as the ability to bend in all directions, to produce fast elongations, and to vary its stiffness. The octopus achieves these unique motor skills, thanks to its peculiar muscular structure, named muscular hydrostat. Different muscles arranged on orthogonal planes generate an antagonistic action on each other in the muscular hydrostat, which does not change its volume during muscle contractions, and allow bending and elongation of the arm and stiffness variation. By drawing inspiration from natural skills of octopus, and by analysing the geometry and mechanics of the muscular structure of its arm, we propose the design of a robot arm consisting of an artificial muscular hydrostat structure, which is completely soft and compliant, but also able to stiffen. In this paper, we discuss the design criteria of the robotic arm and how this design and the special arrangement of its muscular structure may bring the building of a robotic arm into being, by showing the results obtained by mathematical models and prototypical mock-ups.