gebhart/patrepeval huggingface dataset:
Designing new architectures and protocols for wireless sensor networks: a perspective (2005)

Inspiring work in the areas of Wireless Sensor Net- works (WSNs) is being achieved, with Mobile Ad hoc Networks (MANETs) clearly a key ingredient to this. Primary constraints to system design in WSNs are bandwidth, energy, memory and processing. One pattern very evident from the very incipient stages of research in this area is the dominance of Internet design being transported to these environments. Though the Internet architecture is extremely appropriate for its environment, we argue that transporting it to WSN could only prove disastrous. What is to be learnt from the Internet is more a philosophy of building successful stacks. To that end we investigate Stack Aware Architectures and advocate its inclusion in stack de- signs. We also validate this concept by analyzing the Internet architecture for this property. Another pattern very evident in WSN research is that individual modules are validated over a set of workloads at least thought to be representative of the entire application domain. The class of applications and their requirements in WSNs, however, are varied. We go on further to analyze classes of applications that use WSNs, their individual requirements from the layers beneath, and a basic example to a dynamic and adaptive stack for WSN, suited for all application types (based on a per-packet mapping of functions required for it), which of course is also stack aware.
Cyclin D1 Genetic Heterozygosity Regulates Colonic Epithelial Cell Differentiation and Tumor Number in <i>Apc<sup>Min</sup></i> Mice (2004)

Constitutive beta-catenin/Tcf activity, the primary transforming events in colorectal carcinoma, occurs through induction of the Wnt pathway or APC gene mutations that cause familial adenomatous polyposis. Mice carrying Apc mutations in their germ line (ApcMin) develop intestinal adenomas. Here, the crossing of ApcMin with cyclin D1-/- mice reduced the intestinal tumor number in animals genetically heterozygous or nullizygous for cyclin D1. Decreased tumor number in the duodenum, intestines, and colons of ApcMin/cyclin D1+/- mice correlated with reduced cellular proliferation and increased differentiation. Cyclin D1 deficiency reduced DNA synthesis and induced differentiation of colonic epithelial cells harboring mutant APC but not wild-type APC cells in vivo. In previous studies, the complete loss of cyclin D1 through homozygous genetic deletion conveyed breast tumor resistance. The protection of mice, genetically predisposed to intestinal tumorigenesis, through cyclin D1 heterozygosity suggests that modalities that reduce cyclin D1 abundance could provide chemoprotection.
Neodymium:YAG Laser in the Treatment of Gynecologic Malignancies (1983)

The Nd:YAG laser has been used for tumor volume reduction of recurrent gynecologic malignant tumors after previous radiation therapy. The localization of the tumor did not allow conventional surgical resection or surgery was contraindicated because of severe medical problems. Hemorrhage caused by recurrent tumor was controlled by tissue coagulation. The laser beam was delivered by means of a handpiece using the Model 8000 of the Molectron Medical Corporation. A power of 40 to 100 W was used with the maximal pulse duration of 9.9 sec and multiple pulse irradiation. The total energy ranged between 620 and 13.105 Ws. Good palliation was achieved in patients with hemorrhaging tumors of the cervix and ovary metastatic to the vagina.
[New aspects of surgical treatment of glaucoma. Comparison of viscoelastic substances in chamber angle surgery]. (1992)

The development of new viscoelastic substances opens up new perspectives for chamber angle surgery under direct view. The success of "Cyclodialysis ab interno" treating children with glaucoma is often reduced by scar formation of the cleft. Therefore four different viscoelastic substances were instilled during an animal experimental study into the cleft and compared in their effect. We used hyaluronic acid with different molecular weight (Healon and Healon GV) and cross-linked forms of hyaluronan as a fluid and a gel (Hylan fluid and Hylan gel). A cyclodialysis ab interno was performed on 14 eyes of cynomolgus monkeys. The functional results (tonometry, outflow facility, autoradiography) and the morphological findings will be presented and their consequences for an extended indication of the cyclodialysis ab interno will be discussed.
Liquid Chromatography-Tandem Mass Spectrometry Method for Determination of 15 Bile Acids in Human Serum (2007)

A simple,rapid,precise and sensitive liquid chromatography-tandem mass spectrometry(LC-MS/MS) method has been developed and validated for simultaneous determination of 15 bile acids in human serum.Protein precipitation with acetonitrile was used for sample preparation.Liquid chromatographic separation was performed on a Capcell C18 column with gradient eluent consisting of acetonitrile and ammonium acetate buffer, and the flow rate was 0.25 mL/min and injection volume was 10 μL.The deprotonate of analytes was quantitated in the negative ionization mode by the multiple reaction monitoring technique.The method was validated over a wide range of concentrations for all the analytes using a linear regression with 1/x weighting.The intra-and inter-batch relative standard deviations were 2.3%-12.7% and 1.1%-14.3%,respectively.The proposed method was applied to determinate the serum bile acid concentrations in 10 health children.
Inflammatory machenism in the pathogenesis of diabetic retinopathy (2014)

Diabetic retinopathy (DR) is the most common retinal vascular disease and one of the main blinding diseases for people over the age of 50.In recent years,studies have shown that the occurrence of DR is related with several hypothesis such as non-enzymatic glycosylation,activation of protein kinase C,immune or inflammation,polyol pathway,growth factors,oxidative stress/the rennin-angiotensin system and hemodynamic changes,but the exact mechanism has not been fully elucidated.Recently,the role of inflammatory factors in the development of DR has been attracting the attention of scholars both at domestic and abroad,particularlly the tumor necrosis factor alpha (TNFoα),adhesion molecules,vascular endothelial growth factor(VEGF),pigment epithelium-derived factor (PEDF).This article reviews the current studies about the role of inflammatory factors and inflammatory related factors in the pathogenesis of DR.

Key words: 
diabetic retinopathy;  tumor necrosis factor alpha;  adhesion molecules;  vascular endothelial growth factor;  pigment epithelium-derived factor
Feminist pedagogy and feminist epistemology: an overview (1995)

This article offers an overview of the field of feminist education, epistemology and pedagogy. It examines the variety of streams of feminist thought in these areas including socialist, radical, cultural, liberal and postmodern feminisms. In doing so, it engages with some of the most influential writings in the field from the last 12 years and looks at the relationship between feminist education, feminism as a whole, and poststructuralist social theory and postmodernism. The article goes on to discuss epistemology and Foucauldian notions of knowledge and power hierarchies and asks whether feminism accepts notions of ontology in relation to women. In the final section, feminist pedagogy is discussed in relation to other streams of critical or radical pedagogy; is Women's Studies in universities the most productive place to devote feminist energy to? Can Women's Studies be considered part of radical education when it necessarily operates within an institution which arguably operates to ‘domesticate’ women and valorizes traditional, or patriarchal, epistemology? It concludes by exploring an educational environment, or methodology, which has the potential to be more productive for both students and educators interested in the liberatory possibilities of education.
Adaptive rate error control through the use of diversity combining and majority-logic decoding in a hybrid-ARQ protocol (1991)

Diversity combining and majority-logic decoding are combined to create a simple but powerful hybrid automatic repeat request (ARQ) error control scheme. Forward-error-correcting (FEC) majority-logic decoders are modified for use in type-I hybrid-ARQ protocols through the identification of reliability information within the decoding process. Diversity combining is then added to reduce the number of retransmissions and their consequent impact on throughput performance. Packet combining has the added benefit of adapting the effective code rate to channel conditions. Excellent reliability performance coupled with a simple high-speed implementation makes the majority-logic system and ideal choice for high-data-rate error control over both stationary and nonstationary channels.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Characterization of packaging grade papers from recycled raw materials through the study of fibre morphology and composition (2005)

The restrictions in availability of forest-based raw materials along with favourable environmental policies towards alternative sources of raw materials have forced corrugated packaging industry to shift towards recycled paper and other fibre sources such as non-wood and agro-residues. The variability in raw pulp materials with increasing percentages of recycled fibres is a very common technical problem for the corrugated packaging industry worldwide. Corrugating packaging production is facing the challenge to ensure a satisfactory strength of packages despite the increase of recycled paper as the main fibrous component. Sustainable manufacturing of papers of consistent and acceptable quality requests comprehensive characterization of the fibrous components, which are becoming more heterogeneous. Understanding the influence that heterogeneous recycled raw materials have on packaging grade paper properties offers great potential value to the corrugated board and packaging industry. 57 linerboards and corrugating medium were selected to represent all the variety of paper grades available on the market at the moment for the production of corrugated board in Spain. The papers were analyzed for their fibre morphology (fibre length, fibre width, lumen diameter, cell wall width and flexibility) and fibre composition (softwood to hardwood and nonwood fibre count and weight) and their strength (compression, bursting and crushing resistance) was evaluated. All the determinations were in accordance with the relevant TAPPI Test Methods. The significant differences found in most of the anatomical characteristics, fibre composition and strength properties among the paper grades reflected the diverse raw materials used for their production as well as their qualitative differences. By means of simple correlation the influence of fibre characteristics and composition on the strength of the papers was determined under two different conditions, at 23 o C and 50% RH and at 20 o C and 90% RH. The results demonstrate that besides the physical-mechanical characterization of packaging grade papers, fibre anatomy and composition can be used successfully as a complementary practical test to predict the performance of papers. The application of the predicting correlations is proposed for the evaluation of the fibre supplies for the packaging industry. An enormous potential for cost reduction can be created by the selection of the most appropriate and inexpensive combination of grade papers for a specific packaging use.
Recent advances in the total synthesis of cyclopropane-containing natural products (2012)

In this tutorial review, recent advances in the synthesis of cyclopropane-containing natural products are discussed, highlighting the application of novel synthetic methodologies and innovative synthetic strategies in the construction of highly functionalized cyclopropanes. The examples showcased herein aim to inspire students and practitioners of organic synthesis to seek further advances in the chemical synthesis of cyclopropanes, both in the context of target-oriented syntheses and method developments.
Using a CCD Camera Imaging System as a Recording Device to Quantify Human DNA by Slot Blot Hybridization (2001)

Slot blot hybridization of membrane-immobilized, single-stranded human DNA with the higher primate-specific alphoid probe D17Z1 is routinely used in forensic science to estimate the amount of DNA in biological samples. Typically, a chemiluminescent signal captured on film records the hybridization, and the quantity of the signal is related to the amount of immobilized DNA. Digital imaging using a cooled CCD camera offers an alternate non-film-based method for image acquisition with comparable sensitivity of detection, a greater dynamic range, enhanced capability of data interpretation, and often faster results than film. In addition, the data support the premise that more accurate and precise human DNA quantification should be obtained by not assuming a linear response of signal to known standards. Instead, quantity should be estimated using a second-order standard curve (R2 = 0.999). Finally, a CCD camera imaging system offers versatility for image capture of different signal sources and analysis of samples on a variety of support media.
Research on the technology of the automatic test instrument hardware boards recognition (2011)

In the automatic test system,the method of recognizing similar boards needs the distribution of different PID and VID.This method is not only complicated to operate,but also not conducive to upgrade automatic test system.To address these problems,a novel technique,in which similar boards can be recognized by the information of hardware position scanned by the cooperation of driver program and application program,was proposed.The test results proved that driver sharing is realized by this method.In addition,the reading and writing operations of each board can be controlled respectively by PC and the application process of the board are simplified.
Reducing Visual Discomfort with HMDs Using Dynamic Depth of Field (2015)

Although head-mounted displays (HMDs) are ideal devices for personal viewing of immersive stereoscopic content, exposure to VR applications on them results in significant discomfort for the majority of people, with symptoms including eye fatigue, headaches, nausea, and sweating. A conflict between accommodation and vergence depth cues on stereoscopic displays is a significant cause of visual discomfort. This article describes the results of an evaluation used to judge the effectiveness of dynamic depth-of-field (DoF) blur in an effort to reduce discomfort caused by exposure to stereoscopic content on HMDs. Using a commercial game engine implementation, study participants report a reduction of visual discomfort on a simulator sickness questionnaire when DoF blurring is enabled. The study participants reported a decrease in symptom severity caused by HMD exposure, indicating that dynamic DoF can effectively reduce visual discomfort.
Integration of vegetation classification with land cover mapping: lessons from regional mapping efforts in the Americas (2022)

Aims : Natural resource management and biodiversity conservation rely on inventories of vegetation that span multiple management or political jurisdictions. However, while remote sensing data and analytical tools have enabled production of maps at increasing spatial resolution and reliability, there are limited examples where national or continental-scaled maps are produced to represent vegetation at high thematic detail. We illustrate two examples that have bridged the gap between traditional land cover mapping and modern vegetation classification. Study area : Our two case studies include national (USA) and continental (North and South America) vegetation and land cover mapping. These studies span conditions from subpolar to tropical latitudes of the Americas. Methods : Both case studies used a supervised modeling approach with the International Vegetation Classification (IVC) to produce maps that provide for greater thematic detail. Georeferenced locations for these vegetation types are used by machine learning algorithms to train a predictive model and generate a distribution map. Results : The USALANDFIRE (Landscape Fire and Resource Management Planning Tools Project) case study illustrates how a history of vegetation-based classification and availability of key inputs can come together to generate standard map products covering more than 9.8 million km 2 that are unsurpassed anywhere in the world in terms of spatial and thematic resolution. That being said, it also remains clear that mapping at the thematic resolution of the IVC Group and finer resolution require very large and spatially balanced inputs of georeferenced samples. Even with extensive prior data collection efforts, these remain a key limitation. The NatureServe effort for the Americas - encompassing 22% of the global land surface - demonstrates methods and outputs suitable for worldwide application at continental scales. Conclusions : Continued collection of input data used in the case studies could enable mapping at these spatial and thematic resolutions around the globe. Abbreviations: CART = Classification and Regression Tree; CONUS = Conterminous United States; DSWE = Dynamic Surface Water Extent; EPA = United States Environmental Protection Agency; FGDC = Federal Geographic Data Committee; IVC = International Vegetation Classification; LANDFIRE = Landscape Fire and Resource Management Planning Tools Project; LFRDB = LANDFIRE Reference Database; LiDAR = Light Detection and Ranging; NDVI = Normalized Difference Vegetation Index; NLCD = National Land Cover Database; USNVC = United States National Vegetation Classification; USA = United States of America; WWF = World Wildlife Fund or Worldwide Fund for Nature.
Alteration of the cytoplasmic/nuclear expression pattern of galectin-3 correlates with prostate carcinoma progression (2000)

Galectin-3, a member of the beta-galactoside-binding lectin family, is involved in a variety of biological events including interactions with galactose-containing glycoconjugates, cell proliferation, differentiation and apoptosis. Galectin-3 appears to intervene during tumor progression and altered expression patterns have been reported in a variety of malignancies. In our study, we have examined the expression of galectin-3 in a population of 145 prostate carcinoma samples using immunohistochemistry. We found that most of the non-tumoral prostatic glands exhibited moderate immunostaining for galectin-3 localized in both nucleus and cytoplasm. In prostatic cancer cells, galectin-3 was usually not expressed or decreased compared with the normal glands. Interestingly, when galectin-3 was detected in the cancer cells, it was consistently excluded from the nucleus and only present in the cytoplasmic compartment. The latter observation was also made for prostatic intraepithelial neoplasia (PIN) cells. Furthermore, we found that the levels of galectin-3 expression in the cancer cells were significantly associated with prostate-specific antigen (PSA) relapse in univariate analysis (p = 0.044). Cytoplasmic expression of galectin-3 in the carcinoma cells was an independent predictor of disease progression in multivariate analysis, after the pathological stage and the Gleason score. Our data demonstrate that galectin-3 is generally down-regulated in human prostate carcinoma cells, and consistently excluded from the nucleus. Interestingly, specific cytoplasmic expression of galectin-3 in a subset of lesions is associated with disease progression. These results suggest that galectin-3 might play anti-tumor activities when present in the nucleus, whereas it could favor tumor progression when expressed in the cytoplasm. Further studies should determine the exact role and mechanisms by which galectin-3 differentially affects cell behavior in the different locations where it is expressed.
[Role of socio-economy and management in sustainable transmission control of schistosomiasis in Taoyuan County, Hunan Province, China]. (2013)

The harmonious development of socio-economy and the scientific and efficient health system in Taoyuan County are the key factors for the sustainable transmission control of schistosomiasis.
The use of Fmoc‐Lys(Pac)‐OH and penicillin G acylase in the preparation of novel semisynthetic insulin analogs (2007)

In this paper, we present the detailed synthetic protocol and characterization of Fmoc-Lys(Pac)-OH, its use for the preparation of octapeptides H-Gly-Phe-Tyr-N-MePhe-Thr-Lys(Pac)-Pro-Thr-OH and H-Gly-Phe-Phe-His-Thr-Pro-Lys(Pac)-Thr-OH by solid-phase synthesis, trypsin-catalyzed condensation of these octapeptides with desoctapeptide(B23-B30)-insulin, and penicillin G acylase catalyzed cleavage of phenylacetyl (Pac) group from Nepsilon-amino group of lysine to give novel insulin analogs [TyrB25, N-MePheB26,LysB28,ProB29]-insulin and [HisB26]-insulin. These new analogs display 4 and 78% binding affinity respectively to insulin receptor in rat adipose membranes.
Cloning and characterization of the choline acetyltransferase structural gene (cha-1) from C. elegans (1994)

We have cloned the cha-1 gene from Caenorhabditis elegans using the method of transposon tagging, cha-1 is the structural gene for ChAT, the enzyme that synthesizes ACh. Sequence analysis of cDNAs predicts a protein of 71.5 kDa; comparison of the deduced amino acid sequence with ChAT sequences from other species confirms that cha-1 encodes ChAT. Comparison of cDNA and genomic sequences reveals that transcription is from right to left on the genetic map, and that some of the transcripts may result from trans-splicing of the 22-base spliced leader SL 1. The cha-1 gene is organized into 11 exons. The first exon contains only untranslated sequences, and is followed by an extremely long intron. The coding sequence of the cha-1 transcript is disrupted by mutations in the cha-1 gene. We have determined the sites of four transposon insertions and the end-points of two deletions that lead to the cha-1 mutant phenotype; one of the deletions appears to eliminate gene function completely. Comparison of the Drosophila, rat, and C. elegans genes reveals conserved motifs and conserved intron sites.
pH-Responsive Sulfonamide/PEI System for Tumor Specific Gene Delivery:  An in Vitro Study (2005)

The feasibility of pH-sensitive polymeric nanoparticles that effectively target the acidic extracellular matrix of tumors is demonstrated. Plasmid DNA was complexed with polyethyleneimine (PEI) and further with a pH-sensitive diblock copolymer, poly(methacryloyl sulfadimethoxine) (PSD)-block-PEG (PSD-b-PEG), to obtain naonparticles. The shielding/deshielding of nanoparticles was tested along with cell viability and transfection efficiency at physiological and tumor pH. The nanoparticles composed of DNA/PEI/PSD-b-PEG were 300 nm in size and showed low cytotoxicity and transfection at pH 7.4 due to shielding of PEI by PSD-b-PEG. The PSD-b-PEG bound to PEI/DNA complex decreased the interaction of PEI positive charges with cells and reduced the cytotoxicity by 60%. At pH 6.6, the nanoparticles demonstrated high cytotoxicity and transfection, indicating PSD-b-PEG detachment from the nanoparticles and permit PEI to interact with cells. PSD-b-PEG is able to discern the small difference in pH between normal and tumor tissues and hence has remarkable potential in drug targeting to tumor areas.