gebhart/patrepeval huggingface dataset:
Adhesion molecules in the pathogenesis of asthma. (1991)

Using a primate antigen inhalation model the mechanisms involved in the induction of airway hyperresponsiveness were studied. Antigen inhalation induced a prolonged airway eosinophilia. Chronic airway eosinophilia, intratracheal instillation of eosinophil major basic protein, repeated antigen inhalation, and airway epithelial desquamation induced, or were associated with, an increase in airway responsiveness. Using monoclonal antibodies to intercellular adhesion molecule-1 (ICAM-1) and endothelial-leukocyte adhesion molecule-1 (ELAM-1), the contributions of these cell adhesion molecules to antigen-induced airway hyperresponsiveness were studied. ICAM-1 partially mediated eosinophil adhesion to endothelium in vitro, was upregulated on inflamed endothelium and epithelium in vitro and in vivo, and contributed to repeated antigen-induced airway eosinophilia and hyperresponsiveness. ELAM-1 was upregulated on inflamed endothelium (but not epithelium) in vitro and in vivo, but did not contribute to the repeated antigen-induced airway eosinophilia and hyperresponsiveness. These results indicate that antagonism of ICAM-1, but not ELAM-1, may provide a novel therapeutic approach to reducing the airway inflammation and hyperresponsiveness commonly found in asthmatics.
Predicting Falls of a Humanoid Robot through Machine Learning (2010)

Although falls are undesirable in humanoid robots, they are also inevitable, especially as robots get deployed in physically interactive human environments. We consider the problem of fall prediction, i.e., to predict if a robot's balance controller can prevent a fall from the current state. A trigger from the fall predictor is used to switch the robot from a balance maintenance mode to a fall control mode. Hence, it is desirable for the fall predictor to signal imminent falls with sufficient lead time before the actual fall, while minimizing false alarms. Analytical techniques and intuitive rules fail to satisfy these competing objectives on a large robot that is subjected to strong disturbances and therefore exhibits complex dynamics. Today effective supervised learning tools are available for finding patterns in high-dimensional data. Our paper contributes a novel approach to engineer fall data such that a supervised learning method can be exploited to achieve reliable prediction. Specifically, we introduce parameters to control the tradeoff between the false positive rate and lead time. Several parameter combinations yield solutions that improve both the false positive rate and the lead time of hand-coded solutions. Learned predictors are decision lists with typical depths of 5-10, in a 16-dimensional feature space. Experiments are carried out in simulation on an Asimo-like robot.
ChemInform Abstract: ANTIMICROBIAL PROPERTIES OF SOME MIXED DIESTERS OF ALIPHATIC DIOLS (1977)

Abstract Die Aktivität der Diester (I) gegen S.aureusz E.coliz A.flavus, Asgecies und Candida albicans oder Tarula sgecies wird gegrüft.
Burst level congestion control in ATM networks (2002)

We present the architecture for burst level congestion control (BLCC) in ATM networks which is well suited for bursty self-similar traffic. The architecture is based upon pre-planned virtual path (PVP) set and preassigned maximal permitted route rates (MPR). The PVP set and MPR are engineered to meet QoS requirements of multi-service demand. The suggested burst level control maintains the maximal rate of cell admission on any PVP below its MPR. This is done at each PVP's source node by regulating bursts admission and by reserving the burst peak rate for each admitted burst. The reservation can be performed very fast since it is done at PVP's source node without any communication with other nodes. The MPR and PVP set are adjusted in a relatively slow, for instance hourly, timeframe adapting to the changes in the demand. The paper also presents an efficient technique for multiclass QoS engineering of burst admission that can be applied to engineer networks with large number of nodes and service classes.
Characterization of Transcripts from the Synapsin III Gene Locus (1999)

Synapsin III, the most recently described member of the synapsin gene family, displays a gene structure and protein domain structure similar to those of synapsins I and II. In this report, however, we describe major differences in the temporal- and tissue-specific expressions of synapsin III. Whereas synapsins I and II each give rise to two isoforms that are expressed predominantly in adult brain, there are at least six synapsin III transcripts (synapsin IIIa-IIIf) that differ with respect to tissue- and developmental stage-specific expression. Three of the neuronal transcripts are detected in fetal and to a lesser extent in adult brain (IIa-IIIc), whereas one (IIId) is detected only in fetal brain. Two additional transcripts (IIIe and IIIf) are detected only in nonneuronal tissues. A putative second promoter, which is contained within an intron in the synapsin III gene locus, appears to generate the nonneuronal synapsin IIIe and IIIf transcripts. This level of genome complexity is far greater than that described previously for the synapsin I and II genes and suggests that synapsin III may have functions distinct from those described for synapsins I and II.
Optical patient interface in femtosecond laser–assisted cataract surgery: Contact corneal applanation versus liquid immersion (2013)

Curved contact interfaces create corneal folds that can lead to incomplete capsulotomy during laser cataract surgery. A liquid interface eliminated corneal folds, improved globe stability, reduced subconjunctival hemorrhage, and lowered IOP rise.
Data aware, low cost error correction for wireless sensor networks (2004)

One or the main challenges in adoption and deployment of wireless networked sensing applications is ensuring reliable sensor data collection and aggregation, while satisfying the low-cost, low-energy operating constraints of such applications. A wireless sensor network is inherently vulnerable to different sources of unreliability resulting in transient failures. Existing reliability techniques that address transient failures in circuits and communication channels incur prohibitively high energy, bandwidth and cost overheads in the sensor nodes. In this paper we investigate application-level error correction techniques for sensor networks that exploit the properties of sensor data to eliminate any overhead on the sensor nodes, at the expense of nominal buffer requirements at the data aggregator nodes, which are much less cost/energy constrained. Our approach involves use of spatio-temporal correlations in sensor data, the goals of the application, and its vulnerability to various errors. We present our error-correction algorithm and evaluate it through simulations using real and synthetic sensor data. Experimental results validate the feasibility of our approach to provide high degree of reliability in sensor data aggregation, without imposing overheads on sensor nodes.
Aryloxide ligands in the metathesis of olefins: syntheses of W(OAr)xCl6-x complexes with x = 2, 3, and 4. Crystal structures of trichlorotris(2,6-diisopropylphenolato)tungsten and tetrachlorobis(2,6-diphenylphenolato)tungsten (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAryloxide ligands in the metathesis of olefins: syntheses of W(OAr)xCl6-x complexes with x = 2, 3, and 4. Crystal structures of trichlorotris(2,6-diisopropylphenolato)tungsten and tetrachlorobis(2,6-diphenylphenolato)tungstenFrancoise Quignard, Michel Leconte, Jean Marie Basset, Leh Yeh Hsu, John J. Alexander, and Sheldon G. ShoreCite this: Inorg. Chem. 1987, 26, 25, 4272–4277Publication Date (Print):December 1, 1987Publication History Published online1 May 2002Published inissue 1 December 1987https://pubs.acs.org/doi/10.1021/ic00272a026https://doi.org/10.1021/ic00272a026research-articleACS PublicationsRequest reuse permissionsArticle Views329Altmetric-Citations59LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Synthesis of an Orthogonally Protected Precursor to the Glycan Repeating Unit of the Bacterial Cell Wall (2001)

[reaction: see text]. A synthesis of stereochemically pure and orthogonally protected N-acetyl-(2-deoxy-2-aminoglucopyranosyl)-beta-[1,4]-N-acetylmuramyl (NAG-NAM) monopeptide (2), the glycopeptide core of lipid II and of the bacterial cell wall repeating unit, is reported.
On the Design of Prefetching Strategies in a Peer-Driven Video on-Demand System (2006)

In this paper, we examine the prefetching strategies in a peer-driven video on-demand system. In our design, each video is encoded into multiple low bit-rate substreams and copies of the substreams are distributed to the participating peers. When a peer streams in a substream of rate r, it instead streams at rate rcirc, where r>rcirc. In this manner, if one of the peer's suppliers disconnects, the client peer can tap the reservoir of prefetched bits while searching for a replacement server, thereby avoiding any glitches or reduced visual quality. We examine how to assign prefetching rates to each of substreams as a function of their importance. Our studies show that appropriate prefetching strategies can bring significant performance improvements for both multiple description and layered videos
Time-Differential Encoding Of Sinusoidal Model Parameters For Multiple Successive Segments (2004)

Publication in the conference proceedings of EUSIPCO, Viena, Austria, 2004
GitFlow (2015)

Our work addresses the problem of revision control for flow state management in SDN-enabled networks, so that the underlying data plane might be able to provide better state protection, provenance, ease of programmability, and support for multiple applications. Inspired by the revision control tools in the software development world, we propose an abstraction and a system called GitFlow, which provides flow state revisioning in the SDN context. The core idea of GitFlow is to run a repository server to maintain the authoritative copy of the flow configuration state and track additional meta data for each evolving snapshot of the flow state. When multiple applications make incremental commits to state, our system also automates conflict resolution by rebasing new flow state with committed flow state. We envision that our revision control abstraction will provide safety in the data plane and better programmability in the control plane.
Aromatic retinoic acid analogs. 2. Synthesis and pharmacological activity (1983)

Aromatic analogues of (E)-1-(4-carboxyphenyl)-2-methyl-4-(2,6,6-trimethyl-1-cyclohexen-1-yl)butadiene (1b) and its ethyl ester (1a) were synthesized as potential chemopreventive agents for the treatment of epithelial cancer and such skin diseases as psoriasis and cystic acne. The phenyl ring of 1 was replaced by 2-fluorophenyl, 2-methoxyphenyl, thienyl, furanyl, and pyridyl groups. The 1-fluorobutadiene analogue of 1 was also synthesized. With exception for the furanyl analogue, these compounds demonstrated good activity in reversing keratinization in hamster tracheal organ culture and in inhibiting the induction of ornithine decarboxylase in mouse epidermis by a tumor promoter.
3,4-Dihydro-2-Alkoxy-6-Benzyl-4-Oxopyrimidines (DABOs): A New Class of Specific Inhibitors of Human Immunodeficiency Virus Type 1 (1993)

A series of novel 3,4-dihydro-6-benzyl-4-oxopyrimidines substituted at both the C-5 and the C-2 positions were synthesized as potential anti-HIV agents. Preparation of the title compounds was achieved by condensation of O-methylisourea with methyl 2-alkyl-4-phenylacetylacetate and subsequent displacement of the methoxy group by reaction with a series of linear, ramified and cyclic alkoxy groups containing from three to six carbon units. Methyl 2-alkyl-4-phenylacetylacetates were prepared by alkylation of methyl 4-phenylacetylacetate, which was obtained starting from Meldrum's acid and phenacetyl chloride. Acid hydrolysis of 3,4-dihydro-6-benzyl-2-methoxy-4-oxopyrimidines furnished the corresponding 1,2,3,4-tetrahydro-6-benzyl-2,4-dioxopyrimidines. In acutely infected MT-4 cells, compounds 3e, 3o, 3q and 3r showed an anti-HIV-1 activity as potent and/or selective as HEPT and ddl. Unlike HEPT, the replacement of a methyl for an hydrogen atom at position C-5 of 3,4-dihydro-2-alkoxy-6-benzyl-4-oxopyrimidines (DABOs) did not abolish the antiviral activity, as well as the substitution of the C-5 methyl for an ethyl group did not increase the potency. However, similarly to HEPT and its derivatives, DABOs targeted the HIV-1 reverse transcriptase and neither inhibited the multiplication of HIV-2 in acutely infected MT-4 cells, nor that of HIV-1 in chronically infected H9/IIIB cells.
Experimental Design in the Preparation of Modified HEMA-Based Superporous Hydrogels in an Aqueous Medium (2010)

Abstract Due to a relatively large number of excipients and their concentrations, which can be used effectively in the preparation of superporous hydrogels, an experimental design based on the Taguchi matrix has proven to be a very valuable tool in screening and narrowing down the final formulation. In this study, the effect of starting materials, their concentrations as well as the starting reaction temperature, were examined in the preparation of superporous hydrogels based on hydroxyethyl methacrylate. A large number of possible formulations and conditions might lead to the production of a reasonable hydrogel network, but some formulations produce stronger or faster swelling superporous hydrogels than others. The final properties of the superporous hydrogels depend upon the events that occur during formation of the gel, including the presence of atmospheric oxygen, which is responsible for the inhibition period seen at the start of the reaction, and also including the change in temperature at which the reaction starts. These events can be largely affected by the choice of ingredients used in the reaction. For this study, eight variables were chosen, and their effects were examined using a Taguchi matrix. The parameters examined were the maximum temperature during the reaction, the time corresponding to the maximum temperature, and the reaction yield which is represented by the weight of the dry final SPH. Keywords: experimental designgelationinhibition periodpoly (2-hydroxyethyl methacrylate)superporous hydrogelssynthesis Notes All volumes are based on the use of 800 µL HEMA and 100 µL of 10 wt% aqueous F127 solution. The temperature column displays the temperature of the water in the water bath that was used to give heat to the reaction. The Tmax column shows the maximum temperature that was recorded in the reaction mixture. The tmax column gives the time that was required by each reaction to reach its maximum temperature due to exotherm. *No gel was formed. No gelation was observed for the reactions 1, 10, 13, and 17.
Hydrogenation of CO<sub>2</sub> on Fe-Based Catalysts: Preferred Route to Renewable Liquid Fuels (2022)

Catalytic hydrogenation of CO2 can be conducted either in one pot (CO2 hydrogenation) or in two stages (RWGS and CO hydrogenation). Its configuration consists of either three reactors in series with interim water removal (one-pot process) or CO2 separation and recycling (two-stage process) to reach high CO2 conversion. The two-stage process enables to reach optimal H2/CO and temperature in the hydrogenation reactor to yield higher productivity while minimizing production of the aqueous phase, which offset the advantages of the one-pot process. The techno-economic study determined that there is no apparent advantage in operating the hydrogenation reaction in one stage at current green hydrogen prices. The decision between the two routes should be based on catalyst stability and selectivity toward desired products. Blending 10% of liquid product from both processes with fossil fuels at current prices increases the fuel production cost by 30%, which can be offset by higher carbon pricing or equivalent incentives.
Split Flywheel Design with Attitude Jitter Minimization Through Flywheel Phase Control (2009)

Attitude jitter in satellites has degrading effects on the performance of onboard sensors and communication instruments. The effect of jitter is more pronounced in small satellites due to their low inertia and has to be minimized to be able to use instruments that require directional stability. The source of jitter is primarily due to rotational imbalance in devices like reaction wheels, gyroscopes and motors. This paper discusses a novel method of reducing the amplitude of jitter using a split flywheel design and also adds redundancy to the system. The feasibility of this technique is explored in this paper by analyzing the dynamics of the split flywheel, a probable control approach and considering a typical design of the system.
Fundamental statistics of relatively permanent pigmented or vascular skin marks for criminal and victim identification (2011)

Recent technological advances have allowed for a proliferation of digital images that may be involved in crimes. Using these images as evidence in legal cases like child pornography and masked gunmen can be challenging because usually the faces of the suspects are not visible. To perform personal identification in these images, we propose a biometric trait composed of a group of skin marks including, but not limited to, nevi, lentigines, cherry hemangiomas, and seborrheic keratoses. Due to their biological characteristics, we have grouped these as "Relatively Permanent Pigmented or Vascular Skin Marks," abbreviated as RPPVSM. As statistical study of RPPVSM is essential before investigating their discriminative power, we present in this paper the fundamental statistics of RPPVSM. Back torso images were collected from 144 Caucasian, Asian, and Latino males, and a researcher trained in dermatology manually identified their RPPVSMs. The statistical results show that Caucasians tend to have more RPPVSMs than Asians and Latinos, and over 80 percent of middle to low density RPPVSM patterns are independently and uniformly distributed.
Electronic learning aid with means for repeating an element of nonspoken sound (1988)

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MACHINE PERFUSION PRESERVATION OF THE NON-HEART-BEATING DONOR LIVER USING POLYSOL, A NEW PRESERVATION SOLUTION (2004)

P37 Aims: The current situation in organ transplantation, with patients succumbing to awaiting transplantation has led to the attention for suboptimal donors, f.i. the non-heart-beating donor. In these patients the circulation has ceized before harvesting of the organ could be commenced, resulting in warm ischemic damage. In order to facilitate transplantation, these organs need a more optimal preservation method. Recent literature has shown advantages of oxygenated hypothermic machine perfusion (MP) over cold storage (CS) for these marginal organs, which can then even be resuscitated. As a MP preservation solution the modified University of Wisconsin solution (UW-Gluconate) is used. However, this solution causes microvasculatory obstruction, is hard to obtain and expensive. Therefore we have developed Polysol, a colloid based preservation solution containing free radical scavengers, buffers and specific nutrients for the liver. In previous studies this solution has proven to result in equal to better preservation of optimal livers. The aim of this study was to compare our solution Polysol with UW-gluconate, in a non-heart-beating donor rat liver model. Methods: In an isolated perfused rat liver model damage and function were assessed after 24 hours hypothermic MP in UW-G (n=6) or Polysol (n=6). To determine liver parenchymal damage ALT and LDH levels were measured during 60 minutes of normothermic reperfusion with oxygenated Krebs-Henseleit Buffer. Liver function was measured by collection of bile, clearance rate of ammonia. Wet/dry liver weight ratios were determined for evaluation of cellular edema. Control livers were reperfused after 24 hours CS in UW (n=6). Results: Liver damage (U/L) was significantly higher in the control group compared to MP using UW-Gluconate or Polysol (p<0.05). Although the results appear in favour of Polysol as compared to UW-G, these are not significant (ALT, t=60 min: 9.67±2.42 vs 17.63±5.26). Flow at reperfusion (ml/min) was significantly higher when using Polysol as compared to UW-G (33.33±0.92 vs 11.50±2.71: p<0.01). Bile production (μL/hour) was highest when using Polysol as compared to UW-G (390±22.66 vs 153.3±54.72: p<0.01). Ammonia clearance (%) was highest after MP using Polysol as compared to UW-G (92±1.73 vs 53.5±10.96: p<0.01). There was less cellular edema (wet/dry ratio in %) after preservation with Polysol as compared to UW-G (73±0.008 vs 75±0.009), this was significant for Polysol compared to control (73±0.008 vs 77±0.01: p<0.02). Conclusions: Machine perfusion of NHBD rat livers using UW-Gluconate or Polysol results in less hepatocellular damage than cold storage with UW. Machine perfusion of NHBD rat livers in Polysol is superior to machine perfusion in UW-G.
A Proton Conducting Electrolyte Based on Imidazole Supported Inorganic Porous Matrix for the Unhumidified Intermediate Temperature Fuel Cell (2007)

A proton conducting electrolyte based on imidazole supported inorganic porous matrix was examined to obtain the proton conductor that can operate without humidification at intermediate temperature. The proton conductivity of composite electrolytes with large pore size(0.1μm, 10μm) showed high at higher temperature than 363K, and dropped at lower temperature than 363K as well as imidazole(bulk). However the proton conductivity of composite electrolytes with small pore size(4nm) did not drop even at lower than 363K, that is, showed good temperature dependency. In addition coupling acid functional groups on the pore surfaces contribute to the raise of proton conductivity. These results suggest that high proton conductivity at wide range of temperature without humidification could be achieved by controlling pore size and the acid functional groups coupled with the pore surfaces.
Research Progress of a New Solid Oxide Metal-Air Redox Battery for Advanced Energy Storage (2014)

This paper reviews the research progress of a new class of solid oxide metal-air redox batteries for advanced energy storage. This new type of battery is comprised of a reversible solid oxide fuel cell and pair of metal/metal-oxide redox couple. This all solid-state battery has a great potential to surpass the conventional metal-air batteries and redox flow batteries in performance and cost. The paper first discusses the working principle and key features of the new battery, followed by the theoretical analysis of various metal-air chemistries. Finally, two examples of solid oxide metal-air chemistries operated at 550°C are given to demonstrate the promising performance of this innovative battery.