gebhart/patrepeval huggingface dataset:
Graphene–dielectric integrated terahertz metasurfaces (2018)

In this paper we discuss graphene–dielectric integrated terahertz metasurfaces as an alternative approach to graphene–metal metamaterials for providing effective control of electromagnetic beam propagation at terahertz wavelengths. Our structures consist of a passive lossless dielectric pattern and a reconfigurable graphene sheet whose terahertz optical conductivity could be actively tuned chemically, electrically, or optically. In particular, we investigate dielectric patterns consisting of pillar- and circular hole arrays and show that via optimizing the geometric dimensions in these patterns it is possible to attain almost complete terahertz absorption at an arbitrary frequency of interest. Furthermore, via either (i) controlling the thickness of a low-index dielectric spacer located between the dielectric pattern and the graphene sheet, or (ii) choosing a material with an appropriate index of refraction when constructing the dielectric pattern, it is possible to control the sensitivity of the overall structure to variations in the graphene sheet conductivity. Full-wave electromagnetic simulations are supported by proof-of-principle experiments on structures fabricated via patterning of a silicon-on-insulator wafer followed by graphene transfer and chemical doping. Overall, the proposed approach can lead to the construction of efficient tunable terahertz absorbers; however, other tailored electromagnetic responses might be also possible via the selection of appropriate dielectric patterns.
Control of feeding behavior in <i>C. elegans</i> by human G protein-coupled receptors permits screening for agonist-expressing bacteria (2008)

G protein-coupled receptors (GPCRs) have a key role in many biological processes and are important drug targets for many human diseases. Therefore, understanding the molecular interactions between GPCRs and their ligands would improve drug design. Here, we describe an approach that allows the rapid identification of functional agonists expressed in bacteria. Transgenic Caenorhabditis elegans expressing the human chemokine receptor 5 (CCR5) in nociceptive neurons show avoidance behavior on encounter with the ligand MIP-1alpha and avoid feeding on Escherichia coli expressing MIP-1alpha compared with control bacteria. This system allows a simple activity screen, based on the distribution of transgenic worms in a binary food-choice assay, without a requirement for protein purification or tagging. By using this approach, a library of 68 MIP-1alpha variants was screened, and 13 critical agonist residues involved in CCR5 activation were identified, four of which (T8, A9, N22, and A25) have not been described previously, to our knowledge. Identified residues were subsequently validated in receptor binding assays and by calcium flux assays in mammalian cells. This approach serves not only for structure/function studies as demonstrated, but may be used to facilitate the discovery of agonists within bacterial libraries.
Tandem Mooring LNG Offloading System (2002)

Abstract The attractiveness of placing a natural gas liquefaction plant on a vessel moored at or close to an offshore field is known. This vessel can either be part of an oil development in which it liquefies associated gas or a stand alone development of a gas field. In the associated gas case, the Floating LNG (FLNG) unit makes certain oil developments feasible by turning the associated gas disposal into a moneymaking opportunity. In the gas field case, the FLNG makes remote offshore field production economic. The safe reliable transfer of this LNG in open sea, possibly harsh, environment has however not been possible. The proposed LNG Offloading Arm (LOA) effectively combines proven technology and operating experience to effect the safe and reliable transfer of LNG between tandem moored vessels or between a fixed tower and LNG carrier in up to 5 meter significant seas. The concept is based on the experience of mooring systems surviving 100 years storms, dis-connectable mooring systems in typhoon areas and work performed on cryogenic swivels. The LOA structure consists of "vertical" and "horizontal" arm section with swivels to provide articulations required to follow the relative motions between the FLNG and the tandem moored LNG carrier. The vertical section is supported from a cantilevered rotating structure on the back of the FLNG vessel or on a fixed tower. The horizontal section connects the LNG carrier to the lower end of the vertical section. Each section is composed of a central pipe for LNG transfer and a large diameter outer pipe structure also used as the vapor return from the LNG carrier. The LNG carrier can be passivelymoored using gravity restoration by weights located in the horizontal section of the loading arm or DP assisted using both the arm and the LNG carrier thruster system. Introduction The technology for cryogenic liquefaction and storage of LNG on an offshore floating vessel is known. The safe reliable ship to ship transfer of this LNG in an open sea, possibly harsh, environment has however not been possible. SBM having experience in both the supply and operation of mooring systems put this experience to work in the development of a Tandem LNG Offloading system. The philosophy adopted for this development was to keep the design simple and whenever possible stick to components that had a known track record. Having over 40 years experience in the design, supply, and operation of Single Point Mooring (SPM) systems and Floating Production Storage and Offloading (FPSO) systems the value of simple robust design was well understood and applied to this LNG Arm development. Known technology and operational experience either directly or indirectly applied to the Arm include soft yoke or gravity moorings (Fig. l), articulated fluid transfer arms (Fig. 2), cryogenic swivels (Fig. 3a and b) and tandem mooring systems (Fig. 4).
A control method for high power UPSs in parallel operation (2002)

The parallel operation of static inverters is, in a large number of cases, the appropriate solution to achieve the high power required by some applications or to improve system reliability. To higher the power in a lot of industrial applications is equivalent to adding a new UPS unit to an already existing one. In UPS systems there are situations where a high reliability/availability is required by critical loads. Parallel redundancy appears as an immediate solution to satisfy this requirement. This paper presents a control method for parallel operation of non redundant UPSs based on current control. Simulation results as well as experimental ones are presented. The overall control system is implemented on a simple and low cost platform.
Transcriptome-wide measurement of translation by ribosome profiling (2017)

Translation is one of the fundamental processes of life. It comprises the assembly of polypeptides whose amino acid sequence corresponds to the codon sequence of an mRNA's ORF. Translation is performed by the ribosome; therefore, in order to understand translation and its regulation we must be able to determine the numbers and locations of ribosomes on mRNAs in vivo. Furthermore, we must be able to examine their redistribution in different physiological contexts and in response to experimental manipulations. The ribosome profiling method provides us with an opportunity to learn these locations, by sequencing a cDNA library derived from the short fragments of mRNA covered by the ribosome. Since its original description, the ribosome profiling method has undergone continuing development; in this article we describe the method's current state. Important improvements include: the incorporation of sample barcodes to enable library multiplexing, the incorporation of unique molecular identifiers to enable to removal of duplicated sequences, and the replacement of a gel-purification step with the enzymatic degradation of unligated linker.
Canny edge based image expansion (2003)

In this paper, a Canny edge-based image expansion method is introduced. Our proposed expansion method outperforms the pixel replication, the bilinear interpolation and the bicubic interpolation methods. It gives crisp and less zigzag pictures. Our method is applied on the image after it has been expanded using bilinear or bicubic interpolation. The edges of such an expanded image are obtained using the Canny edge detector. The values of pixels around the edges are modified to yield a crisper and less zigzagged picture.
MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity (2007)

Members of the thiazolidinedione (TZD) class of insulin-sensitizing drugs are extensively used in the treatment of type 2 diabetes. Pioglitazone, a member of the TZD family, has been shown to bind specifically to a protein named mitoNEET [Colca JR, McDonald WG, Waldon DJ, Leone JW, Lull JM, Bannow CA, Lund ET, Mathews WR (2004) Am J Physiol 286:E252-E260]. Bioinformatic analysis reveals that mitoNEET is a member of a small family of proteins containing a domain annotated as a CDGSH-type zinc finger. Although annotated as a zinc finger protein, mitoNEET contains no zinc, but instead contains 1.6 mol of Fe per mole of protein. The conserved sequence C-X-C-X(2)-(S/T)-X(3)-P-X-C-D-G-(S/A/T)-H is a defining feature of this unique family of proteins and is likely involved in iron binding. Localization studies demonstrate that mitoNEET is an integral protein present in the outer mitochondrial membrane. An amino-terminal anchor sequence tethers the protein to the outer membrane with the CDGSH domain oriented toward the cytoplasm. Cardiac mitochondria isolated from mitoNEET-null mice demonstrate a reduced oxidative capacity, suggesting that mito- NEET is an important iron-containing protein involved in the control of maximal mitochondrial respiratory rates.
Near-field radiative thermal transport: From theory to experiment (2015)

Radiative thermal transport via the fluctuating electromagnetic near-field has recently attracted increasing attention due to its fundamental importance and its impact on a range of applications from data storage to thermal management and energy conversion. After a brief historical account of radiative thermal transport, we summarize the basics of fluctuational electrodynamics, a theoretical framework for the study of radiative heat transfer in terms of thermally excited propagating and evanescent electromagnetic waves. Various approaches to modeling near-field thermal transport are briefly discussed, together with key results and proposals for manipulation and utilization of radiative heat flow. Subsequently, we review the experimental advances in the characterization of both near-field heat flow and energy density. We conclude with remarks on the opportunities and challenges for future explorations of radiative heat transfer at the nanoscale.
Unveiling facebook (2008)

Online social networking sites such as Facebook and MySpace have become increasingly popular, with close to 500 million users as of August 2008. The introduction of the Facebook Developer Platform and OpenSocial allows third-party developers to launch their own applications for the existing massive user base. The viral growth of these social applications can potentially influence how content is produced and consumed in the future Internet.
Coupling of plasmon and photon modes in a graphene-based multilayer structure (2015)

We propose a graphene-based plasmonic heterostructure in which a new class of plasmon polariton modes can be realized via fundamental coupling of conventional graphene plasmons (GPs) and spoof surface plasmons or radiation modes. We name these electromagnetic modes coupled graphene plasmon polaritons (CGPPs). It is found that the properties of the CGPPs can be tuned by the geometry of the heterostructure, the material used to fill the holes, and the electron density in graphene. Most interestingly, we show that it is possible to achieve CGPPs with about 10 times enhancement of wave localization or about 300 times enhancement of propagation length, compared to usual GPs through varying device parameters. These features can be applied to tunable terahertz and infrared plasmonic devices.
The Virtues and Challenges of Ad Hoc + Streams Querying in Finance (2003)

Financial trading strategies are based on queries over time-ordered data. The strategies value very recent data over older data, but require information about older data to avoid making poor decisions. One can imagine a streaming architecture that keeps a synopsis of older information available for many possible queries, but this may be too crude - and too expensive ‐ an approximation of the query requirements. Instead, we show several fundamental query types for which traders would prefer to issue an ad hoc query Q and then allow updates to change the answer to Q over time. To make the ad hoc portion fast, the architecture puts historical data into a well-structured form (organized by security and time) to support rapid querying whereas recent data is ordered by time alone. Periodically, some of the older recent data is moved to the historical data structures. The net effect is to allow queries to look at very recent and less recent data efficiently and only when needed. Several new research issues arise in this setting.
Microwave-assisted magnetization reversal in 0.36-μm-wide Permalloy wires (2007)

Microwave-assisted magnetization reversal in a 0.36μm wide Ni80Fe20 wire with a natural ferromagnetic resonance frequency of 8.42GHz was investigated experimentally. Magnetization switching could be detected from a discontinuous change in the ferromagnetic resonance frequency of the wire. The application of microwaves with a frequency of 7.5GHz and a power of 19.2dBm reduced the switching field from 217to142Oe. While high-power microwave-assisted switching reduced the dc switching field, it substantially broadened the switching field distribution. This is mainly attributed to inhomogeneous resonance properties of the nucleation sites in the wire.
Evaluation of Noise Removal of Radiance Data on Onboard Data Compression of Hyperspectral Imagery (2005)

Abstract:- This paper evaluates the impact of removing random noise of radiance data using a spectral-spatial smoothing approach on data compression onboard a hyperspectral satellite. A datacube acquired using a Short Wave Infrared Full Spectrum Imager II for target detection application of hyperspectral data was tested. The impact was evaluated using both the statistical based measures and a remote sensing application. The evaluation results show that compression on radiance data after removal of random noise produces better reconstruction fidelity and much higher evaluation scores for the remote sensing application than compression on radiance data without removal of random noise. The evaluation results indicate that random noise of radiance data should be removed before compression, if data compression is applied on radiance data onboard. Key-Words:- Hyperspectral imagery, onboard data compression, noise removal, evaluation of impact
mmWave Measurement of RF Reflectors for 5G Green Communications (2018)

In recent years, with the energy consumption and environmental degradation, science and technology embarked on a path of sustainable development. In this situation, 5G green communication system has been widely used. This paper introduces the application of RF reflectors to 5G mmWave, where line‐of‐sight (LoS) blockage is a major hindrance for the coverage. In particular, we investigate the lab measurement of RF reflectors, which is a critical step from the theory to the practice. Furthermore, through the lab measurement, a 3D near‐field range migration (RM) imaging algorithm for MIMO array configuration is proposed, and the sampling scheme is improved to save the computation time while providing high‐quality images.
플래시 메모리 마모 균등화를 위한 임계값 제어에 관한 연구 (2012)

데이터 저장장치로 널리 사용되고 있는 플래시 메모리의 블록들은 소거 횟수가 제한되어 있어서 특정 블록에 소거 동작이 집중되지 않도록 마모 균등화 기능을 제공해야 한다. 저장 장치의 데이터들은 주기적으로 갱신이 자주 되는 hot데이터와 갱신이 거의 일어나지 않는 cold 데이터로 구성된다. 이런 두 가지 타입의 데이터로 인해 발생하는 소거 횟수에 대한 편차를 줄이기 위하여 정적 마모 균등화 기법을 사용하는데 데이터 이동에 따른 추가적인 소거 동작이 발생하게 된다. 본 논문에서는 데이터 이동 결정을 위한 임계값을 제어하여 플래시 메모리 내의 전체 블록들의 평균 소거 횟수가 크지 않을 때는 마모 균등화 작업을 자주 발생하지 않게 하고, 평균 소거 횟수가 소거 허용 한계치에 점차 근접하면 설정된 임계값으로 동작하도록 하여 정적 마모 평준화에 의해 추가되는 소거 횟수를 효율적으로 감소시키는 방법을 제안한다.
Management of perovskite intermediates for highly efficient inverted planar heterojunction perovskite solar cells (2017)

The management of perovskite intermediates to construct perovskite films with uniform perovskite crystals and controlled surface morphology was introduced.
An efficient solution for the response of electrical well logging tools in a complex environment (1991)

A symmetrical form of the solution for an electrical source in a multibed well-logging environment is derived. The method uses local reflection and transmission operators of a single-bed boundary and a general recursive algorithm to derive generalized reflection and transmission operators. Using this method, the computation time scales linearly as N, where N is the number of beds in the environment. A computer program was developed to implement the solution. The program is robust and generates accurate results from 20 kHz to 25 MHz.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Design of High-precision and Large-power High-voltage DC Power Supply with Modules in Parallel (2008)

A kind of current share parallel enlarged power technique for the multi-modular large-power high-voltage power supply was given.More series-resonant large-power high-voltage modules were operated through the pulse frequency modulator with a constant relative phase shift.The control system of the constant relative phase shift and the compensate net were discussed in detail.The problem of the system self-excitation and the effect of strike fire at high voltage were resolved.The results show: The parallel enlarged power of Multi-modular is feasible in this way;This technique is simple and reliable and the output voltage ripple is less with the more paralleled modules;The satisfied result of the current share can be achieved without inside current control loop;A faster system response is acquired in the conditions of pulse load and resistor load.
Characteristics of transient outward current in human ventricular myocytes from patients with terminal heart failure. (1993)

A variety of outward currents exists in ventricular myocardium of different species influencing action potential duration and electrical activity. Transient outward currents have been reported in ventricular tissue of some animals but are small or absent in others. This study was conducted to investigate whether a transient outward current exists in human ventricular myocardium and to characterize its basic electrophysiological properties. Currents were recorded from enzymatically isolated human ventricular myocytes obtained from explanted hearts of 22 patients with terminal heart failure. In almost all cells studied, a transient outward current could be recorded on depolarization to between -20 and +80 mV. The size of the transient outward current was usually large enough to mask the Ca2+ current. It could be recorded under conditions in which Ca2+ influx and intracellular Ca2+ transients were suppressed. Basic current characteristics were similar to transient outward currents observed in other species. Inactivation of the transient outward current was monoexponential, with a time constant of 54.8 +/- 3.7 milliseconds at +40 mV. Half-maximal activation occurred at 16.7 +/- 1.6 mV; half-maximal steady-state inactivation occurred at -34.5 +/- 2.3 mV. Frequency-dependent reduction of peak transient outward current was 29.8 +/- 1.4% at 2 Hz compared with resting conditions. Recovery from inactivation was voltage dependent and had a biexponential time course; the faster time constant (41.0 +/- 6.5 milliseconds at -80 mV) accounted for 86.0 +/- 5.2% of total current. The transient outward current was sensitive to 4-aminopyridine (IC50, 1.15 mM). These results indicate that a large Ca(2+)-independent transient outward K+ current is present in human ventricular myocytes that might be regulated by physiological or pathological events and is a potential site for pharmacological intervention.
<title>On-chip binary image processing with CMOS image sensors</title> (2002)

In this paper, we demonstrate a CMOS active pixel sensor chip, integrated with binary image processing on a single monolithic chip. A prototype chip comprising a 64 X 64 photodiode array with on-chip binary image processing is fabricated in standard 0.35 micrometers CMOS technology, with 3.3 V power supply. The binary image processing functionality is embedded in the column structure, were each processing element is placed per column, reducing processing time and power consumption. This column processing structure is scalable to higher resolution. A 3 X 3 local mask (also called structure element) is implemented every column so that row-parallel processing can be achieved with a conventional progressive scanning method.
Quantitation of Rh D Antigen Sites on Weak D and D Variant Red Cells by Flow Cytometry (1996)

Information on the number of D sites on weak D (Du) and D variant cells is limited and incomplete. The aim of this study was to use a simple non-isotopic technique utilising a combination of flow cytometry and ELISA to quantitate the number of D sites on an extensive range of these cells. Five human monoclonal IgG anti-D (BRAD-7 (JAC10), BRAD-5, 2B6, BRAD-3, H27) and one affinity-purified polyclonal IgG anti-D were each used at a saturating concentration of 20 micrograms/ml. In general, BRAD-3, BRAD-5 and 2B6 gave the highest number of D sites per cell (SPC), H27 and the polyclonal anti-D were slightly lower, while BRAD-7 gave the lowest SPC with all D-positive cells tested except DFR. Interestingly, BRAD-7 gave the highest SPC with DFR cells. Rh D antigen density for R2R2 cells was approximately double that seen with either R2r or Rzero (presumed R0r) cells. R1R1 cells gave only moderately higher SPC than R1r cells.Higher SPC were obtained with the R1 haplotype if the CW antigen was present. Weak D, Va and VI cells of the R1 haplotype had higher SPC than those of the Rzero or R2 haplotypes. The majority of D variant cells were found to have lower SPC than normal cells, and for polyclonal anti-D, which was the only anti-D to react with all D variants, SPC decreased in the order IIIc > IIIa > HMii > IVa > Va > DFR > DBT > IVb > VII > II > HMi > VI. The number of molecules of IgG anti-D bound to D variant cells varied by up to 10 times with reactive monoclonal antibodies. The highest SPC on weak D and D variant cells were obtained with BRAD-7 (DFR, 9,500), BRAD-3 (Va, 12,500), BRAD-5 (II, 5,500; VII, 5,300; weak D, 1,300), H27 (III, 24,000; VI, 2,900; HMi, 3,000; HMii, 16,800) and polyclonal anti-D (IVa, 9,300; IVb, 4,000; DBT, 4,300).
Design and Synthesis of Selective Phosphodiesterase 4D (PDE4D) Allosteric Inhibitors for the Treatment of Fragile X Syndrome and Other Brain Disorders (2019)

Novel pyridine- and pyrimidine-based allosteric inhibitors are reported that achieve PDE4D subtype selectivity through recognition of a single amino acid difference on a key regulatory domain, known as UCR2, that opens and closes over the catalytic site for cAMP hydrolysis. The design and optimization of lead compounds was based on iterative analysis of X-ray crystal structures combined with metabolite identification. Selectivity for the activated, dimeric form of PDE4D provided potent memory enhancing effects in a mouse model of novel object recognition with improved tolerability and reduced vascular toxicity over earlier PDE4 inhibitors that lack subtype selectivity. The lead compound, 28 (BPN14770), has entered midstage, human phase 2 clinical trials for the treatment of Fragile X Syndrome.