gebhart/patrepeval huggingface dataset:
Influence of In Vitro IL-2 or IL-15 Alone or in Combination with Hsp 70 Derived 14-Mer Peptide (TKD) on the Expression of NK Cell Activatory and Inhibitory Receptors on Peripheral Blood T Cells, B Cells and NKT Cells (2016)

Previous studies from Multhoff and colleagues reported that plasma membrane Hsp70 acts as a tumour-specific recognition structure for activated NK cells, and that the incubation of NK cells with Hsp70 and/or a 14-mer peptide derived from the N-terminal sequence of Hsp70 (TKDNNLLGRFELSG, TKD, aa 450-463) plus a low dose of IL-2 triggers NK cell proliferation and migration, and their capacity to kill cancer cells expressing membrane Hsp70. Herein, we have used flow cytometry to determine the influence of in vitro stimulation of peripheral blood mononuclear cells from healthy individuals with IL-2 or IL-15, either alone or in combination with TKD peptide on the cell surface expression of CD94, NK cell activatory receptors (CD16, NK2D, NKG2C, NKp30, NKp44, NKp46, NKp80, KIR2DL4, DNAM-1 and LAMP1) and NK cell inhibitory receptors (NKG2A, KIR2DL2/L3, LIR1/ILT-2 and NKR-P1A) by CD3+CD56+ (NKT), CD3+CD4+, CD3+CD8+ and CD19+ populations. NKG2D, DNAM-1, LAMP1 and NKR-P1A expression was upregulated after the stimulation with IL-2 or IL-15 alone or in combination with TKD in NKT, CD8+ T cells and B cells. CD94 was upregulated in NKT and CD8+ T cells. Concurrently, an increase in a number of CD8+ T cells expressing LIR1/ILT-2 and CD4+ T cells positive for NKR-P1A was observed. The proportion of CD8+ T cells that expressed NKG2D was higher after IL-2/TKD treatment, when compared with IL-2 treatment alone. In comparison with IL-15 alone, IL-15/TKD treatment increased the proportion of NKT cells that were positive for CD94, LAMP1 and NKRP-1A. The more potent effect of IL-15/TKD on cell surface expression of NKG2D, LIR1/ILT-2 and NKRP-1A was observed in B cells compared with IL-15 alone. However, this increase was not of statistical significance. IL-2/TKD induced significant upregulation of LAMP1 in CD8+ T cells compared with IL-2 alone. Besides NK cells, other immunocompetent cells present within the fraction of peripheral blood mononuclear cells were influenced by the treatment with low-dose interleukins themselves or in combination with hsp70 derived (TKD) peptide.
SimIC: Designing a New Inter-cloud Simulation Platform for Integrating Large-Scale Resource Management (2013)

'Simulating the Inter-Cloud' (SimIC) is a discrete event simulation toolkit based on the process oriented simulation package of SimJava. The SimIC aims of replicating an inter-cloud facility wherein multiple clouds collaborate with each other for distributing service requests with regards to the desired simulation setup. The package encompasses the fundamental entities of the inter-cloud meta-scheduling algorithm such as users, meta-brokers, local-brokers, datacenters, hosts, hyper visors and virtual machines (VMs). Additionally, resource discovery and scheduling policies together with VMs allocation, re-scheduling and VM migration strategies are included as well. Using the SimIC a modeler can design a fully dynamic inter-cloud setting wherein collaboration is founded on meta-scheduling inspired characteristics of distributed resource managers that exchange user requirements as driven events in real-time simulations. The SimIC aims of achieving interoperability, flexibility and service elasticity while at the same time introducing the notion of heterogeneity of multiple clouds' configurations. In addition it accepts an optimization of a variety of selected performance criteria for a diversity of entities. The crucial factor of dynamics consideration has implemented by allowing reactive orchestration based on current workload of already executed heterogeneous user specifications. These are in the form of text files that the modeler can load in the toolkit and occurs in real-time at different simulation intervals. Finally, a unique request is scheduled for execution to an internal cloud datacenter host VM that is capable of performing the service contract. This is formally designed in Service Level Agreements (SLAs) based upon user profiling.
Hydrogenolysis of Glycerol in Gas Phase on Cu-Cr Mixed Oxide Catalyst Doped with Ni (2017)

Hydrogenolysis of glycerol was conducted on catalyst of the type mixed oxide of Cu-Cr doped with NiO on g-Al2O3. The prepared catalyst was analyzed by XRD, IR and TPR. Catalytic tests were carried out on a laboratory plant in continuous flow system on a reactor equipped with heating mantle, at molar ratio of glycerol / hydrogen of 1/300, glycerol volume hourly space velocities 1000s-1, temperatures 200-220oC and pressures 3-5 bar. The main reaction products identified were propylene glycol and hydroxyacetone. Glycerol conversion increases with temperature and pressure on ranges of parameters studied. Selectivity to propylene glycol increases with increasing of temperature and pressure and the selectivity to hydroxyacetone decreases with increasing of temperature and pressure on the variation range of the parameters studied.
Neural Generation for Czech: Data and Baselines (2019)

We present the first dataset targeted at end-toend NLG in Czech in the restaurant domain, along with several strong baseline models using the sequence-to-sequence approach. While non-English NLG is under-explored in general, Czech, as a morphologically rich language, makes the task even harder: Since Czech requires inflecting named entities, delexicalization or copy mechanisms do not work out-ofthe-box and lexicalizing the generated outputs is non-trivial.
A Chinese Internet? History, practice, and globalization (2012)

Click to increase image sizeClick to decrease image sizeKeywords: InternetChinahistorypracticeglobalization
Multimedia electronic mail (1991)

article Free AccessMultimedia electronic mail: will the dream become a reality? Author: Nathaniel S. Borenstein Bellcore, Morristown, NJ Bellcore, Morristown, NJView Profile Authors Info & Claims Communications of the ACMVolume 34Issue 4April 1991 pp 117–119https://doi.org/10.1145/103085.103098Published:01 April 1991Publication History 17citation396DownloadsMetricsTotal Citations17Total Downloads396Last 12 Months52Last 6 weeks3 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
CSF vasopressin concentration is reduced in Alzheimer's disease (1986)

The concentration of arginine vasopressin (AVP) was measured in cerebrospinal fluid (CSF) by radioimmunoassay. Serial dilution curves and reversed-phase high-pressure liquid chromatography (HPLC) showed that the material measured behaved identically to authentic vasopressin. Levels of CSF AVP were reduced by 37% in Alzheimer's disease, but were normal in Huntington's disease, normal-pressure hydrocephalus, and several other neurologic disorders. On direct comparison, the CSF AVP concentration was significantly lower in Alzheimer's disease than in normal-pressure hydrocephalus. Low CSF levels of AVP may therefore assist in the identification of demented patients who are not likely to benefit from ventricular shunting.
Applications of hydrofluoride ceramic membranes for advanced fuel cell technology (2000)

New types of materials, hydrofluoride-alumina ceramic composites containing one hydride component, CaH2, have been studied for fuel cell applications. Excellent fuel cell performances were achieved for a peak power density of 180 mW cm-2 at 300 mA cm-2, and a short-circuit current density near 1000 mA cm-2. In fuel cell measurements the conductivity and ionic transport properties of the hydrofluoride-based electrolytes have also been investigated. During fuel cell operation, water was often observed at the cathode (air side), indicating that proton conduction occurs in these electrolyte materials. The experiments show an interesting chance for the future development of innovative fuel cell technology for commercialization. Copyright © 2000 John Wiley & Sons, Ltd.
Experimental heterotopic heart transplantation without ischemia or reperfusion. (1991)

Current experimental models of heart transplantation include a period of ischemia after donor harvest, resulting in rhythm disturbances, myocardial distention, and reperfusion injury on implantation. A model of cervical heterotopic heart transplantation that avoids ischemia by using retrograde perfusion was developed. More than 100 consecutive successful transplantations have been performed both as control protocols and as a part of experimental protocols. The advantages of this technique include: avoidance of ischemia and reperfusion injury, prevention of myocardial damage caused by overdistention, and potential evaluation of pretreatment regimens for transplanted hearts.
Automatic Speaker Identification from Interpersonal Synchrony of Body Motion Behavioral Patterns in Multi-Person Videos (2015)

Interpersonal synchrony, i.e. the temporal coordination of persons during social interactions, was traditionally studied by developmental psychologists. It now holds an important role in fields such as social signal processing, usually treated as a dyadic issue. In this paper, we focus on the behavioral patterns from body motion to identify subtle social interactions in the context of multi-person discussion panels, typically involving more than two interacting individuals. We propose a computer-vision based approach for automatic speaker identification that takes advantage of body motion interpersonal synchrony between participants. The approach characterizes human body motion with a novel feature descriptor based on the pixel change history of multiple body regions, which is then used to classify the motor behavioral patterns of the participants into speaking/non-speaking. Our approach was evaluated on a challenging dataset of video segments from discussion panel scenes collected from YouTube. Results are very promising and suggest that interpersonal synchrony of motion behavior is indeed indicative of speaker/listener roles.
W-band Dual-Large-Reflectarray Antenna with Low Sensitivity and Broad bandwidth Characteristic (2019)

The dual-large-reflectarray antenna with low sensitivity and broad bandwidth characteristics is presented. The proposed unit cell is composed of a simple multi-resonant element which is a patch and a square loop. Then, the low sensitivity and broad bandwidth can be achieved through the stepwise variation strategy rather than the conventional variation method of the unit cell. With this multi-resonant element, the total range of 430° and the average sensitivity of 15.9°/0.1mm can be achieved. A 6072-element large reflectarray antenna is designed, simulated. Finally, the simulated results show that the peak gain is 35.9 dBi and the 1-dB gain bandwidth is 12GHz in W-band.
Capturing learner's activity events from a mobile learning system using adaptive event framework (2015)

Several mobile-enabled solutions for education transformation have been deployed in Africa. Drawbacks of these systems include, a predominant focus on disseminating bulk learning content, student outcomes are measured solely on quantitative performance metrics, a lack of instrumentation to capture fine-grained user interaction data, and finally none of them seem to focus on capturing the contextual factors affecting learners. Hence, there are few chances to fully empower educators to create effective interventions for their students. In this paper, we present an adaptive event framework library that can be embedded within a blended learning environment. It enables the capturing of fine-grained learners activity stream data, including learners sentiment and context information. We conducted a limited controlled experiment to evaluate the effectiveness of the event framework. The real time visualizations provide useful insights to teachers in understanding their classroom and/or individual student engagement and progress. Finally, we outline challenges and preliminary solution how such system can be deployed in resource constrained environments.
The V<sub>FB</sub> Modulation Effect of ALD Grown Al<sub>2</sub>O<sub>3</sub>, SrO, La<sub>2</sub>O<sub>3</sub> Capping Layers with HfO<sub>2</sub> Gate Dielectrics (2010)

The effect of atomic layer deposited Al2O3, SrO, and La2O3 capping layers with HfO2 gate dielectrics were examined ffor flat band voltage (VFB) modulation. Al2O3 capping layers cause a VFB shift into the positive voltage direction, while SrO and La2O3 capping layers cause a shift into the negative voltage direction. The bottom capping layer, which positions between the Si substrate and the HfO2 dielectric was more effective in modulating the VFB compared to the top capping layer. The insulating properties of the gate dielectric stacks with different capping layers were also examined. X-ray photoelectron spectroscopy analysis verified that top capping layers did not generally diffuse to the interface between the Si substrate and the HfO2 dielectrics, which supports the result that bottom capping layers are more effective in modulating the VFB.
Preparation of polybenzoxazole fibers via electrospinning and postspun thermal cyclization of polyhydroxyamide (2008)

Abstract Polybenzoxazole (PBO) fibers with a submicron diameter were successfully prepared by electrospinning its precursor, polyhydroxyamide (PHA), solutions to obtain the PHA fibers first, followed by appropriate thermal treatments for cyclization reaction. BisAPAF‐IC PHA with two different molecular weights (MWs) were synthesized from a low temperature polymerization of 2,2′‐bis(3‐amino‐4‐hydroxyphenyl) hexafluoropropane (BisAPAF) and isophthaloyl chloride (IC). Using dimethylacetamide (DMAc) and tetrahydrofuran (THF), solvent effects on the electrospinnability of PHA solutions were investigated. For balancing the solution properties, it was found that DMAc/THF mixture with a weight ratio of 1/9 was the best cosolvent to prepare smooth PHA fibers; uniform PHA fibers with a diameter of 325–720 nm were obtained by using 20 wt % PHA/(DMAc/THF) solutions. For a fixed PHA concentration, solutions with a lower MW of PHA yielded thinner electrospun fibers under the same electrospinning condition. After obtaining the electrospun BisAPAF‐IC PHA fibers, subsequent thermal cyclization up to 350 °C produced the corresponding thermally stable BisAPAF‐IC PBO fibers with a diameter of 305–645 nm. The structure of the precursor fibers and the fully cyclized fibers were characterized by FTIR. For the cyclized BisAPAF‐IC PBO fibers, thermogravimetric analysis showed a 5% weight loss temperature at 523 °C in nitrogen atmosphere. The interconnected fiber structure in the BisAPAF‐IC PBO fiber mats was irrelevant to the curing process, but resulted from the jet merging during the whipping process as revealed by the high speed camera images. © 2008 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 46: 8159–8169, 2008
Spectroscopic and electrochemical response to nitrogen monoxide of a cationic iron porphyrin immobilized in nafion-coated electrodes or membranes (1994)

Nafion membranes containing immobilized FeIII tetrakis(N-methyl-4-pyridyl)porphyrin show spectroscopic changes in the UV–VIS range after exposure to gaseous NO, indicating the formation of a nitrosyl complex; electroreduction of NO is mediated by this metalloporphyrin when immobilized in Nafion-coated glassy-carbon electrodes and the use of these film electrodes for the amperometric determination of NO in aqueous solutions is demonstrated.
Power-Efficient Accelerator Design for Neural Networks Using Computation Reuse (2016)

Applications of neural networks in various fields of research and technology have expanded widely in recent years. In particular, applications with inherent tolerance to accuracy loss, such as signal processing and multimedia applications, are highly suited to the approximation property of neural networks. This approximation property has been exploited in many existing neural network accelerators to trade-off accuracy for power-efficiency and speed. In addition to the power saving obtained by approximation, we observed that a considerable amount of arithmetic operations in neural networks are repetitive and can be eliminated to further decrease power consumption. Given this observation, we propose CORN, COmputation Reuse-aware Neural network accelerator that allows neurons to share their computation results, effectively eliminating the power usage of redundant computations. We will show that CORN lowers power consumption by 26 percent on average over low-power neural network accelerators.
Non-alcoholic fatty liver disease and its relationship with cardiovascular disease and other extrahepatic diseases (2017)

Key physiological functions of the liver, including glucose and lipid metabolism, become disturbed in the setting of non-alcoholic fatty liver disease (NAFLD) and may be associated with a systemic inflammatory '<i>milieu</i>' initiated in part by liver-secreted cytokines and molecules. Consequently, the pathophysiological effects of NAFLD extend beyond the liver with a large body of clinical evidence demonstrating NAFLD to be independently associated with both prevalent and incident cardiovascular disease (CVD), chronic kidney disease (CKD) and type 2 diabetes mellitus (T2DM). The magnitude of risk of developing these extrahepatic diseases parallels the underlying severity of NAFLD, such that patients with non-alcoholic steatohepatitis (NASH) appear to be at greater risk of incident CVD, CKD and T2DM than those with simple steatosis. Other modifiers of risk may include genetic variants (eg, patatin-like phospholipase domain-containing 3 and trans-membrane 6 superfamily member 2 polymorphisms), visceral adipose tissue accumulation, dietary intake and the gut microbiome. Emerging data also suggest that NAFLD may be a risk factor for colonic neoplasia and reduced bone mineral density, especially among men. Importantly, improvement/resolution of NAFLD is associated with a reduced incidence of T2DM and improved kidney function, adding weight to causality and suggesting liver focused treatments may reduce risk of extrahepatic complications. Awareness of these associations is important for the clinicians such that CVD risk factor management, screening for T2DM and CKD are part of the routine management of patients with NAFLD.
A scalable, highly-multiplexed delta-encoded digital feedback ECoG recording amplifier with common and differential-mode artifact suppression (2017)

We present a scalable, highly multiplexed CMOS electro-cortocography (ECoG) recording front-end capable of differential-mode and common-mode artifact suppression. The front-end digitally delta-encodes 8-bit data converters to achieve 14-bit resolution. A single, shared mixed-signal front-end is time-division multiplexed to 64 differential input channels; this reduces channel area by 10x compared to the state-of-the-art. A return-to-zero scheme effectively eliminates channel crosstalk. We present performance and in-vivo measurement results of a 65nm CMOS test-chip implementation of the proposed architecture.
Communities of Practice (2018)

For TESOL professionals worldwide, communities of practice offer opportunities for learning and for professional development—both online and face‐to‐face. This entry provides a description of what communities of practice are in English language teaching and how they work to promote excellence in instruction and professional development. The definition of “communities of practice” provided here serves two functions: (1) to identify specific characteristics of TESOL communities of practice; and (2) to connect TESOL with other professional communities of practice. The definition, drawn from many sources, is “TESOL communities of practice are sets of relations among persons and activities over time in relation with other tangential and overlapping communities of practice.”
Prolonged and enhanced secretion of glucagon-like peptide 1 (7-36 amide) after oral sucrose due to α-glucosidase inhibition (acarbose) in Type 2 diabetic patients (1998)

GLP-1, an incretin hormone of the enteroinsular axis with insulinotropic and glucagonostatic activity, is secreted after nutrient ingestion. GLP-1 is mainly produced by intestinal L-cells in the lower gastrointestinal tract (GIT); simple carbohydrates are absorbed in the upper GIT and alpha-glucosidase inhibition leads to augmented and prolonged GLP-1 release in normal subjects. In a cross-over study, 100 mg acarbose or placebo was administered simultaneously with 100 g sucrose to 11 hyperglycaemic Type 2 diabetic patients poorly controlled with diet and sulphonylureas. Plasma levels of GLP-1, insulin, C-peptide, glugacon, GIP, glucose and H2-exhalation were measured over 6 h. Differences in the integrated responses over the observation period were evaluated by repeated measurement analysis of variance with fasting values used as covariates. With acarbose, sucrose reached the colon 60-90 min after ingestion as indicated by a significant increment in breath hydrogen exhalation (p = 0.005). After an early GLP-1 increment 15 min after sucrose under both conditions, GLP-1 release was prolonged in the acarbose group (p = 0.001; significant from 210 to 360 min.). Initially (0-150 min), glucose (p = 0.001), insulin (p = 0.001), and GIP (p < 0.001) were suppressed by acarbose, whereas later there were no significant differences. Glucagon levels were higher with acarbose in the last 3 h of the 6 h observation period (p = 0.02). We conclude that in hyperglycaemic Type 2 diabetic patients, ingestion of acarbose with a sucrose load leads to elevated and prolonged GLP-1 release.
Evaluation of dynamic range in acousto-optic phase processor (2002)

The paper presents the results of an investigation concerning the dynamic range in an interferometric acousto-optic phase processor. Interaction between the laser light and acoustic waves results in the appearance of an interference image. There are factors which have influence on the light intensity of the interference image. Experimental results are presented for the following operating conditions of the acousto-optic phase processor-normal operating conditions, the effect of CCD camera saturation, low signals.
Bcl-2:Beclin 1 complex: multiple, mechanisms regulating autophagy/apoptosis toggle switch. (2012)

Cancer cells have developed novel mechanisms for evading chemotherapy-induced apoptosis and autophagy-associated cell death pathways. Upon the discovery that chemotherapeutics could target these cell death pathways in a manner that was not mutually exclusive, new discoveries about the interrelationship between these two pathways are emerging. Key proteins originally thought to be "autophagy-related proteins" are now found to be involved in either inducing or inhibiting apoptosis. Similarly, apoptosis inhibiting proteins can also block autophagy-associated cell death. One example is the complex formed by the autophagy protein, Beclin 1, and anti-apoptotic protein Bcl-2, which leads to inhibition of autophagy-associated cell death. Researchers have been investigating additional mechanisms that form/disrupt this complex in order to better design chemotherapeutics. This review will highlight the role Bcl-2 and Beclin 1 play in cancer development and drug resistance, as well as the role the Bcl-2:Beclin 1 complex in the switch between autophagy and apoptosis.