gebhart/patrepeval huggingface dataset:
Synthesis of Two Tumor-Associated Oligosaccharides: Di- and Trifucosylated Para-Lacto-<i>N</i>-Hexaose (1991)

ABSTRACT Di- and trifucosylated derivatives (21 and 22) of para-lacto-N-hexaose were synthesized. Both structures have been shown to be present in small quantities in human milk, and have also been indicated as tumor-associated antigens. Thioglycoside mono- and disaccharide blocks were used to assemble a properly protected linear hexaose. Di- and trifucosylation at appropriate positions followed by deprotection then gave the desired oligosaccharides.
C-OPT: Coverage-Aware Trajectory Optimization Under Uncertainty (2016)

We introduce a new problem of continuous, coverage-aware trajectory optimization under localization and sensing uncertainty. In this problem, the goal is to plan a path from a start state to a goal state that maximizes the coverage of a user-specified region while minimizing the control costs of the robot and the probability of collision with the environment. We present a principled method for quantifying the coverage sensing uncertainty of the robot. We use this sensing uncertainty along with the uncertainty in robot localization to develop C-OPT, a coverage-optimization algorithm which optimizes trajectories over belief-space to find locally optimal coverage paths. We highlight the applicability of our approach in multiple simulated scenarios inspired by surveillance, UAV crop analysis, and search-and-rescue tasks. We also present a case study on a physical, differential-drive robot. We also provide quantitative and qualitative analysis of the paths generated by our approach.
Herpes simplex virus type-selective enzyme-linked immunosorbent assay with Helix pomatia lectin-purified antigens (1984)

Helix pomatia lectin-purified antigens with specific reactivity to herpes simplex virus type 1 (HSV-1) and HSV-2 antibodies in human sera were used in an enzyme-linked immunosorbent assay. The type specificity of the antigens was assessed by double immunodiffusion precipitation in gel against rabbit HSV-1 and HSV-2 hyperimmune sera, and by enzyme-linked immunosorbent assay with human reference sera containing antibodies to either type of HSV. Fifty-two sera from patients with documented infection with either HSV-1 or HSV-2 were assayed for HSV type-specific immunoglobulin G antibodies. The reactivity of the sera against lectin-purified antigens correlated completely with the results of virus typing. We conclude that HSV type-specific immunoglobulin G antibodies can easily be measured by enzyme-linked immunosorbent assay with the use of Helix pomatia lectin-purified HSV-1 and HSV-2 antigens.
Path to the measurement of positive gain on the 1315-nm transition of atomic iodine pumped by O/sub 2/(a/sup 1//spl Delta/) produced in an electric discharge (2005)

Laser action at 1315 nm on the I(/sup 2/P/sub 1/2/)/spl rarr/I(/sup 2/P/sub 3/2/) transition of atomic iodine is conventionally obtained by a near-resonant energy transfer from O/sub 2/(a/sup 1//spl Delta/) which is produced using wet-solution chemistry. The system difficulties of chemically producing O/sub 2/(a/sup 1//spl Delta/) have motivated investigations into gas phase methods to produce O/sub 2/(a/sup 1//spl Delta/) using low-pressure electric discharges. We report on the path that led to the measurement of positive gain on the 1315-nm transition of atomic iodine where the O/sub 2/(a/sup 1//spl Delta/) was produced in a flowing electric discharge. Atomic oxygen was found to play both positive and deleterious roles in this system, and as such the excess atomic oxygen was scavenged by NO/sub 2/ to minimize the deleterious effects. The discharge production of O/sub 2/(a/sup 1//spl Delta/) was enhanced by the addition of a small proportion of NO to lower the ionization threshold of the gas mixture. The electric discharge was upstream of a continuously flowing supersonic cavity, which was employed to lower the temperature of the flow and shift the equilibrium of atomic iodine more in favor of the I(/sup 2/P/sub 1/2/) state. A tunable diode laser system capable of scanning the entire line shape of the (3,4) hyperfine transition of iodine provided the gain measurements.
<title>Practical concerns for phase diversity implementation in wavefront sensing and image recovery</title> (2002)

In this paper, we present the results of the phase diversity algorithm applied to simulated and laboratory data. We show that the exact amount of defocus distance does not need to be known exactly for phase diversity algorithm. We determine, through simulation, the optimum diversity distance. We compare the aberrations recovered with the phase diversity algorithm and those measured with a Fizeau interferometer using a HeNe laser. The two aberration sets agree with a Strehl of over 0.9. The contrast of the recovered object is found to be 10 times that of the raw image.
Mechanism of inhibition of a tumor lipid-mobilizing factor by eicosapentaenoic acid. (1998)

Stimulation of lipolysis or adenylate cyclase activity by either isoprenaline or a tumor-derived lipid-mobilizing factor was effectively attenuated in isolated white adipocytes or in adipocyte plasma membranes pretreated with eicosapentaenoic acid (EPA) dissolved in ethanol or from mice dosed p.o. with EPA (1.25 g/kg). A similar effect was observed with docosahexanoic acid (DHA) that may be partly due to retroconversion to EPA. Stimulation of adenylate cyclase activity by forskolin, which acts directly on the enzyme without the involvement of a receptor, was also decreased in membranes of mice treated with EPA, suggesting a direct interaction between EPA and adenylate cyclase. Pertussis toxin eliminated the inhibition of lipolysis and the stimulation of adenylate cyclase by isoprenaline and lipid-mobilizing factor in the presence of EPA, but not DHA. This suggests that the attenuation of hormonal stimulation of adenylate cyclase by EPA was due, at least in part, to an inhibitory guanine nucleotide-binding protein-mediated inhibition of adenylate cyclase activity. The effect of DHA may be due to a direct inhibition of the cyclase catalytic component. The ability of EPA to preserve fat stores during the process of cachexia seems to arise from the attenuation of the stimulation of adenylate cyclase.
Acyclic stereoselection. 11. Double stereodifferentiation as a method for achieving superior Cram's rule selectivity in aldol condensations with chiral aldehydes (1981)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAcyclic stereoselection. 11. Double stereodifferentiation as a method for achieving superior Cram's rule selectivity in aldol condensations with chiral aldehydesClayton H. Heathcock, Charles T. White, James Jeffery Morrison, and Don VanDerveerCite this: J. Org. Chem. 1981, 46, 7, 1296–1309Publication Date (Print):March 1, 1981Publication History Published online1 May 2002Published inissue 1 March 1981https://pubs.acs.org/doi/10.1021/jo00320a014https://doi.org/10.1021/jo00320a014research-articleACS PublicationsRequest reuse permissionsArticle Views986Altmetric-Citations117LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Real-Time Temporal Superpixels for Unsupervised Remote Photoplethysmography (2018)

Segmentation is a critical step for many computer vision applications. Among them, the remote photoplethysmography technique is significantly impacted by the quality of region of interest segmentation. With the heart-rate estimation accuracy, the processing time is obviously a key issue for real-time monitoring. Recent face detection algorithms can perform real-time processing, however for unsupervised algorithms, i.e. without any subject detection based on supervised learning, existing methods are not able to achieve real-time on regular platform. In this paper, we propose a new method to perform real-time unsupervised remote photoplethysmograhy based on efficient temporally propagated superpixels segmentation. The proposed method performs the segmentation step by implicitly identifying the superpixel boundaries. Hence, only a fraction of the image is used to perform the segmentation which reduces greatly the computational burden of the process. The segmentation quality remains comparable to state of the art methods while computational time is divided by a factor up to 8 times. The efficiency of the superpixel segmentation allow us to propose a real-time unsupervised rPPG algorithm considering frames of 640x480, RGB, at 25 frames per second on a single core platform. We obtained realtime processing for 93% of precision at 2.5 beat per minute using our inhouse video database.
Intelligent Use of Big Data for Heavy Oil Reservoir Management (2015)

Abstract In recent years, the application of Big Data technologies and associated analytics has enjoyed significant attention and has seen an enormous growth in the oil industry. This is due to exponential growth of both historical and real-time data being collected. In this article, we present examples of the successful application of these technologies for the management and optimization of large heavy oil reservoirs. These particular reservoirs present a very interesting, yet complex, challenge given the steam assisted gravity drainage recovery mechanism and the thousands of producers, injectors, and observation wells which generate terabytes of data on a daily basis. To handle all this large and high-dimensional information efficiently, we introduced new workflows consisting of operational domain data acquisition, data transfer to business domain, storage in accessible repositories, and ending with data consumption, quality control, visualization and analytics. The paper summarizes how big data is aggregated into smart applications to monitor the reservoirs and observe steamflood recovery development. Examples of high definition DTS data integrated with completion, wellbore equipment, geologic markers, and real-time wellhead pressure showing reservoir heating and/or cooling are presented. Intelligent visualization tools and analytics, such as pattern recognition applied on static and dynamic subsurface data enabled superior heat management. A second example of high efficiency operations enabled by big data is the well integrity during cyclic steam operations. Pressure and injection rate data streams are integrated with analytics to monitor and identify abnormal operating conditions. Lastly, an example of facility reliability and production impact quantification is demonstrated through use of integration of surface system stream data and subsurface well information. The later led to significant business impact in terms of realized production and operation cost savings. The examples presented in this paper demonstrate the business impact and value creation generated by efficient use of the Big Data technologies and associated analytics for heavy oil reservoir management and optimization. The workflows are now used in all Chevron heavy oil fields in San Joaquin Valley.
A Deadly Organometallic Luminescent Probe: Anticancer Activity of a Re<sup>I</sup> Bisquinoline Complex (2014)

The photophysical properties of [Re(CO)3 (L-N3)]Br (L-N3 =2-azido-N,N-bis[(quinolin-2-yl)methyl]ethanamine), which could not be localized in cancer cells by fluorescence microscopy, have been revisited in order to evaluate its use as a luminescent probe in a biological environment. The Re(I) complex displays concentration-dependent residual fluorescence besides the expected phosphorescence, and the nature of the emitting excited states have been evaluated by DFT and time-dependent (TD) DFT methods. The results show that fluorescence occurs from a (1) LC/MLCT state, whereas phosphorescence mainly stems from a (3) LC state, in contrast to previous assignments. We found that our luminescent probe, [Re(CO)3 (L-N3)]Br, exhibits an interesting cytotoxic activity in the low micromolar range in various cancer cell lines. Several biochemical assays were performed to unveil the cytotoxic mechanism of the organometallic Re(I) bisquinoline complex. [Re(CO)3 (L-N3)]Br was found to be stable in human plasma indicating that [Re(CO)3 (L-N3)]Br itself and not a decomposition product is responsible for the observed cytotoxicity. Addition of [Re(CO)3 (L-N3)]Br to MCF-7 breast cancer cells grown on a biosensor chip micro-bioreactor immediately led to reduced cellular respiration and increased glycolysis, indicating a large shift in cellular metabolism and inhibition of mitochondrial activity. Further analysis of respiration of isolated mitochondria clearly showed that mitochondrial respiratory activity was a direct target of [Re(CO)3 (L-N3)]Br and involved two modes of action, namely increased respiration at lower concentrations, potentially through increased proton transport through the inner mitochondrial membrane, and efficient blocking of respiration at higher concentrations. Thus, we believe that the direct targeting of mitochondria in cells by [Re(CO)3 (L-N3)]Br is responsible for the anticancer activity.
Software agent architecture for consistency checking of distributed documents (2001)

Available from British Library Document Supply Centre- DSC:DXN061917 / BLDSC - British Library Document Supply Centre
Cowpox virus encodes a fifth member of the tumor necrosis factor receptor family: A soluble, secreted CD30 homologue (2002)

Cowpox virus (Brighton Red strain) possesses one of the largest genomes in the Orthopoxvirus genus. Sequence analysis of a region of the genome that is type-specific for cowpox virus identified a gene, vCD30, encoding a soluble, secreted protein that is the fifth member of the tumor necrosis factor receptor family known to be encoded by cowpox virus. The vCD30 protein contains 110 aa, including a 21-residue signal peptide, a potential O-linked glycosylation site, and a 58-aa sequence sharing 51-59% identity with highly conserved extracellular segments of both mouse and human CD30. A vCD30Fc fusion protein binds CD153 (CD30 ligand) specifically, and it completely inhibits CD153/CD30 interactions. Although the functions of CD30 are not well understood, the existence of vCD30 suggests that the cellular receptor plays a significant role in normal immune responses. Viral inhibition of CD30 also lends support to the potential therapeutic value of targeting CD30 in human inflammatory and autoimmune diseases.
A reusable distributed software architecture driven by metadata (2003)

This is a work in progress paper where authors are involved in a Telco corporation reengineering project of a half terabyte data warehouse (DW). Firstly the DW context is introduced. Then we discuss the actual implicit architecture found in the runtime system, identifying the problems. Finally the proposed architecture is presented. It has two views: a static, made with filters and pipes, and a dynamic based on an event driven scheduler, as opposed to a fixed time one. In the runtime scenario, the scheduler reads the pipe configurations from the metadata repository, and then executes on the fly the planed filters, transforming data into business information.
An Overview of Blockchain-based Applications for Consumer Electronics (2019)

A high number of research initiatives investigated the advantages of blockchain technology in different sectors. The objective of this work is to present an overview of blockchain-based applications in the consumer electronics field. In particular this work reports around fifty blockchain initiatives in the contexts of healthcare, smart homes, smart cities, automotive and smart devices, and discusses advantages/limitations of this technology.
Solvent Content in Thin Spin-Coated Polystyrene Homopolymer Films (2008)

The solvent content of thin polystyrene (PS) films, spin-coated from protonated and deuterated toluene onto silicon substrates, is investigated. Neutron reflectometry (NR) is used to probe the total remaining solvent inside the PS films in a nondestructive and noninvasive way. In freshly prepared films, the investigated parameters are the molecular weight of PS and the total film thickness. Moreover, the effect of postproduction treatment by annealing at temperatures below and above the glass transition of PS as well as long-term storage over 2 years are examined to deduce the reduction of the remaining solvent. The remaining solvent content increases with increasing molecular weight and with increasing film thickness. An enrichment of toluene at the Si/polymer interface is found. Under the different annealing and storage conditions tested, the remaining solvent is not totally removed. The observed behavior is discussed in the framework of polymer thin films and compared with results obtained by alternative experimental approaches.
Chemical Routes for Production of Transition‐Metal Phosphides on the Nanoscale: Implications for Advanced Magnetic and Catalytic Materials (2004)

Nanoparticulate transition-metal phosphides remain an unexplored, though emerging area of interest on the materials landscape, due principally to their promising magnetic and catalytic properties. This review describes synthetic strategies for the formation of both supported and unsupported transition-metal phosphide nanoparticles, provides a summary of their relevant magnetic and catalytic properties, and indicates new directions for exploration.
Website link structure evaluation and improvement based on user visiting patterns (2001)

Link structure evaluation and improvement is a significant hard problem for Hypertext system. In this paper a novel approach for evaluating and improving website link structure based on User Visiting Patterns instead of complex semantic analysis is proposed. By optimizing and re-evaluating the link structure to increase the Average Connectivity, our approach can effectively improve website link structure. Experiments have shown satisfactory results.
A Prospective Cohort Study Examining the Associations of Dietary Calcium Intake with All-Cause and Cardiovascular Mortality in Older Chinese Community-Dwelling People (2013)

Higher intake of dietary calcium was associated with reduced risk of all-cause mortality and possibly cardiovascular mortality in Chinese older people with low habitual calcium intake.
The Genetic Relationship between Commencement of Luteal Activity and Calving Interval, Body Condition Score, Production, and Linear Type Traits in Holstein-Friesian Dairy Cattle (2002)

The decline of fertility in the UK dairy herd and the unfavorable genetic correlation (r(a)) between fertility and milk yield has necessitated the broadening of breeding goals to include fertility. The coefficient of genetic variation present in fertility is of similar magnitude to that present in production traits; however, traditional measurements of fertility (such as calving interval, days open, nonreturn rate) have low heritability (h2 < 0.05), and recording is often poor, hindering identification of genetically superior animals. An alternative approach is to use endocrine measurements of fertility such as interval to commencement of luteal activity postpartum (CLA), which has a higher h2 (0.16 to 0.23) and is free from management bias. Although CLA has favorable phenotypic correlations with traditional measures of fertility, if it is to be used in a selection index, the genetic correlation (ra) of this trait with fertility and other components of the index must be estimated. The aim of the analyses reported here was to obtain information on the ra between lnCLA and calving interval (CI), average body condition score (BCS; one to nine, an indicator of energy balance estimated from records taken at different months of lactation), production and a number of linear type traits. Genetic models were fitted using ASREML, and r(a) were inferred from genetic regression of lnCLA on sire-predicted transmitting abilities (PTA) for the trait concerned by multiplying the regression coefficient (b) by the ratio of the genetic standard deviations. The inferred r(a) between lnCLA and CI and average BCS were 0.36 and -0.84, respectively. Genetic correlations between InCLA and milk fat and protein yields were all positive and ranged between 0.33 and 0.69. Genetic correlations between InCLA and linear type traits reflecting body structure ranged from -0.25 to 0.15, and between udder characteristics they ranged from -0.16 to 0.05. Thus, incorporation of endocrine parameters of fertility, such as CIA, into a fertility index may offer the potential to improve the accuracy of breeding value prediction for fertility, thus allowing producers to make more informed selection decisions.
An automated method for BER characteristics measurement (2002)

Traditionally the bit error rate characteristics (BER) was measured for a certain number of bit-energy-to-noise ratio, Eb/No. For each point a sample of r bits is used which depends on the expected BER value. The smaller BER value the bigger the sample r. Thus, to obtain the same accuracy at each point a method of errors and trials should be used. Therefore this method extends the time of measurement and measure BER values at all points with different accuracy. This paper presents a method which allows the automated and accurate measurement of the BER characteristics at a number of points with equal accuracy at each point by using the minimum sample size r. The method is tested by measuring BER characteristics of a FFSK modem.
Vibrational spectra and structure of polyaniline (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTVibrational spectra and structure of polyanilineY. Furukawa, F. Ueda, Y. Hyodo, I. Harada, T. Nakajima, and T. KawagoeCite this: Macromolecules 1988, 21, 5, 1297–1305Publication Date (Print):May 1, 1988Publication History Published online1 May 2002Published inissue 1 May 1988https://pubs.acs.org/doi/10.1021/ma00183a020https://doi.org/10.1021/ma00183a020research-articleACS PublicationsRequest reuse permissionsArticle Views1827Altmetric-Citations589LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts