gebhart/patrepeval huggingface dataset:
Homeostatic neuro-metasurfaces for dynamic wireless channel management (2022)

The physical basis of a smart city, the wireless channel, plays an important role in coordinating functions across a variety of systems and disordered environments, with numerous applications in wireless communication. However, conventional wireless channel typically necessitates high-complexity and energy-consuming hardware, and it is hindered by lengthy and iterative optimization strategies. Here, we introduce the concept of homeostatic neuro-metasurfaces to automatically and monolithically manage wireless channel in dynamics. These neuro-metasurfaces relieve the heavy reliance on traditional radio frequency components and embrace two iconic traits: They require no iterative computation and no human participation. In doing so, we develop a flexible deep learning paradigm for the global inverse design of large-scale metasurfaces, reaching an accuracy greater than 90%. In a full perception-decision-action experiment, our concept is demonstrated through a preliminary proof-of-concept verification and an on-demand wireless channel management. Our work provides a key advance for the next generation of electromagnetic smart cities.
Etching techniques for realizing optical micro-cavity atom traps on silicon (2004)

We have fabricated curved optical micromirrors on silicon. We expect to be able to form open optical cavities between these mirrors and plane mirrors coated on the ends of optical fibres. The curved mirror templates have been prepared with less than 10 nm surface roughness by means of isotropic chemical etching. Two different methods are used for the fabrication of the mirrors: the first method uses a silicon oxide mask, while the second uses dry etching to form an indentation in the silicon surface that is opened out by wet isotropic etching. After coating the silicon substrate with gold, good quality mirrors are obtained with R ∼ 98% in the near infra-red. We find that a reflectivity of approximately 98% can be achieved by this method. Cavities formed from these mirrors will be useful for manipulating single atoms.
Liquid sensing system based on two port SH-SAW resonator (1999)

A new liquid flow sensing system constructed with SH-SAW resonator was used to characterize liquid properties. Surface acoustic waves with the shear horizontal displacement (SH-SAW) have been used for sensing the properties in liquid phase. The SH-SAW resonator having two port was fabricated on a 36° rotated Y cut X prop. LiTaO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> (36YX LiTaO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> ) substrate. The flow of a sample liquid was precisely controlled by a liquid chromatography system. The transient responses were detected as sensor response by the two-port SAW resonator. The results showed a specific feature and are used to determine the liquid properties.
In Ictu Oculi: Exposing AI Created Fake Videos by Detecting Eye Blinking (2018)

The new developments in deep generative networks have significantly improve the quality and efficiency in generating realistically-looking fake face videos. In this work, we describe a new method to expose fake face videos generated with deep neural network models. Our method is based on detection of eye blinking in the videos, which is a physiological signal that is not well presented in the synthesized fake videos. Our method is evaluated over benchmarks of eye-blinking detection datasets and shows promising performance on detecting videos generated with DNN based software DeepFake.
A 60GHz 65nm CMOS RMS power detector for antenna impedance mismatch detection (2009)

This paper presents a 60 GHz 65 nm CMOS RMS power detector to be used in a Power Amplifier regulation loop. The presented test-chip integrates also a differential capacitive coupler sensing the RF voltage on a differential transmission line. The circuit shows 25 dB of linear detection range at 60 GHz, well enough to cover a VSWR of up to 7:1 caused by antenna impedance mismatch while still having 10 dB margin for output power regulation. The detector consumes only 50 muA from a 1.2 V power supply and occupies an active area of 80 times 80 mum <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> .
Distributed Recursive Least-Squares for Consensus-Based In-Network Adaptive Estimation (2009)

Recursive least-squares (RLS) schemes are of paramount importance for reducing complexity and memory requirements in estimating stationary signals as well as for tracking nonstationary processes, especially when the state and/or data model are not available and fast convergence rates are at a premium. To this end, a fully distributed (D-) RLS algorithm is developed for use by wireless sensor networks (WSNs) whereby sensors exchange messages with one-hop neighbors to consent on the network-wide estimates adaptively. The WSNs considered here do not necessarily possess a Hamiltonian cycle, while the inter-sensor links are challenged by communication noise. The novel algorithm is obtained after judiciously reformulating the exponentially-weighted least-squares cost into a separable form, which is then optimized via the alternating-direction method of multipliers. If powerful error control codes are utilized and communication noise is not an issue, D-RLS is modified to reduce communication overhead when compared to existing noise-unaware alternatives. Numerical simulations demonstrate that D-RLS can outperform existing approaches in terms of estimation performance and noise resilience, while it has the potential of performing efficient tracking.
Mapping and sequencing the human genome (1997)

article Free Access Share on Mapping and sequencing the human genome: a beginner's guide to the computational science perspective Author: Wayne Smith View Profile Authors Info & Claims XRDS: Crossroads, The ACM Magazine for StudentsVolume 4Issue 1September 1997 pp 13–16https://doi.org/10.1145/270985.270990Online:01 October 1997Publication History 1citation122DownloadsMetricsTotal Citations1Total Downloads122Last 12 Months2Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteView all FormatsPDF
Von Doriskos nach Therme. Der Weg des Xerxes-Heeres durch Thrakien und Ostmakedonien (2017)

Автор реконструирует маршрут движения персидского войска по северному побережью Эгейского моря в 480 г. до н.э.
A comparative study of the effects of genistein and 2-methoxyestradiol on the proteolytic balance and tumour cell proliferation (1999)

The cytotoxicity of two compounds described as anti-angiogenic, the isoflavone genistein and the oestrogen metabolite 2-methoxyestradiol, has been studied in different human tumour cell lines. Since the degradation of the extracellular matrix is one of the essential steps in angiogenesis, the potential modulatory effects of both compounds on the proteolytic balance in media conditioned by different human tumour cells have been also investigated. The IC50 values for 2-methoxyestradiol were lower than those for genistein on all the cell lines tested. In all the cell lines expressing measurable amounts of active enzymes, genistein induced a shift towards antiproteolysis in both matrix metalloproteinase/tissue inhibitor of metalloproteinase and urokinase/plasminogen activator inhibitor proteolytic balances. On the other hand, 2-methoxyestradiol did not produce any clear net shift of the proteolytic balance, with the significant exception of the matrix metalloproteinase/tissue inhibitor of metalloproteinase balance in WAC-2 cells, a neuroblastoma cell line with enhanced expression of the N-myc oncogene.
Measurement of Interleukin 16 (1997)

Interleukin 16 (IL-16) is a chemoattractant immunomodulatory cytokine that initiates its cellular responses through interaction with membrane-expressed CD4. The protein may be detected by a number of methods; the choice of protocol will depend on the ultimate object of a particular experiment. The first method presented is the use of ELISA to measure IL-16 in cell culture supernatants or biological fluids. For some applications, such as identification of IL-16 in an unknown fluid or medium or direct assessment of its bioactivity, functional assays of IL-16-induced responses may be more appropriate. The chemotactic effects of IL-16 on CD4+ T cells and its specific inhibition may be measured using anti-IL-16 antibodies; the same approach may also be applied to monocytes or eosinophils. Another effect of IL-16 is the induction of CD25, which can be assayed using immunological staining. Finally, cell cycle progression in target cells can be measured by the incorporation of radiolabeled thymidine and confirmed by inhibition with neutralizing antibody.
A method to discretize non‐planar fractures for 3D subsurface flow and transport simulations (2007)

Abstract A method is presented to discretize inclined non‐planar 2D fractures within a 3D finite element grid for subsurface flow and transport simulations. Each 2D fracture is represented as a triangulated surface. Each triangle is then discretized by 2D fracture elements that can be horizontal, vertical or inclined and that can be triangular or rectangular. The 3D grid representing a porous rock formation consists of hexahedra and can be irregular to allow grid refinement. An inclined fracture was discretized by (a) inclined triangles and (b) orthogonal rectangles and flow/transport simulations were run to compare the results. The comparison showed that (i) inclined fracture elements must be used to simulate 2D transient flow, (ii) results of 2D/3D steady‐state and 3D transient flow simulations are identical for both discretization methods, (iii) inclined fracture elements must be used to simulate 2D/3D transport because orthogonal fracture elements significantly underestimate concentrations, and (iv) orthogonal elements can be used to simulate 2D/3D transport if fracture permeability is corrected and multiplied by the ratio of fracture surface areas (orthogonal to inclined). Groundwater flow at a potential site for long‐term disposal of spent nuclear fuel was simulated where a complex 3D fracture network was discretized with this technique. The large‐scale simulation demonstrates that the proposed discretization procedure offers new possibilities to simulate flow and transport in complex 3D fracture networks. The new procedure has the further advantage that the same grid can be used for different realizations of a fracture network model with no need to regenerate the grid. Copyright © 2007 John Wiley & Sons, Ltd.
Multiple-image super-resolution on mobile devices: an image warping approach (2017)

This paper discusses a super-resolution (SR) system implemented on a mobile device. We utilized an Android device’s camera to take successive shots and applied a classical multiple-image super-resolution (SR) technique that utilized a set of low-resolution (LR) images. Images taken from the mobile device are subjected to our proposed filtering scheme wherein images that have noticeable presence of blur are discarded to avoid outliers from affecting the produced high-resolution (HR) image. The remaining subset of images are subjected to non-local means denoising, then feature-matched against the first reference LR image. Successive images are then aligned with respect to the first image via affine and perspective warping transformations. The LR images are then upsampled using bicubic interpolation. An L 2-norm minimization approach, which is essentially taking the pixel-wise mean of the aligned images, is performed to produce the final HR image. Our study shows that our proposed method performs better than the bicubic interpolation, which makes its implementation in a mobile device quite feasible. We have also proven in our experiments that there are substantial differences from images captured using burst mode that can be utilized by an SR algorithm to create an HR image.
Synovial Hemangioma of the Knee Joint: a case report (2009)

Synovial hemangioma is a rare benign tumor, yet an important cause of knee symptoms. We reported a 45-year-old male presented with pain and swelling in the left knee joint. Plain radiography showed a small calcification over the suprapatellar region. Sonography of left knee revealed a heterogeneously hypoechoic lesion with increased blood f low and a calcified spot. Computed tomography demonstrated two nodular lesions with moderate degree of contrast enhancement. MRI study showed two nodular lesions with serpentine structure, showing high signal intensity on T2-weighted images. After arthroscopic examination, arthroscopic surgical excision was performed. The pathologic results proved synovial hemangioma.
Potent and selective inhibitors of human peptidylglycine α-amidating monooxygenase (2011)

Fatty acid glycolates are nanomolar inhibitors of small cell lung carcinoma peptidylglycine α-amidating monooxygenase, with binding affinities orders of magnitude stronger than those of the analogous thioesters, the corresponding substrate glycine derivatives or the natural substrate procalcitonin.
Synergizing Rice Yellow Stem Borer Pheromone with Addition of Plant Extracts and Vitamin E (2002)

Rice yellow stem borer, Scirpophaga incertulas Walker YSB females produce sex pheromone to attract males for mating! Synthetic pheromone blend (3:1 blend of Z-ll-hexadecinal and Z-9-hexadecinal) is now used for monitoring and direct control of this pest through mass trapping and mating disruption. The present studies were conducted during Kharif 1999 and Rabi 2000 seasons with all the three (vitamin E, Pusa Basmati and Pheromone) components to know the effect of these on trap catch and possibility of using them in mass trapping technique for better efficacy. The results revealed significant increase (almost doubled) in the trap catch with addition of Pusa Basmati and Vitamin E to the synthetic pheromone than only pheromone, followed by reduced borer damage and increased egg parasitism.
Emerging standards for design management systems (1988)

Standards for engineering design management and guidelines for building design management systems are discussed. Several model for managing electronic product data, managing the design process, and setting up integrated design support environments are reviewed. These models are tied together in an overview of the efforts to the IEEE design automation standard subcommittee (DASS) working group on design management, tasked with producing recommended practices for all aspects of design management.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Isolation of the intermediate filament protein vimentin by chromatofocusing (1985)

A novel, simple and relatively rapid method is described for the isolation of the intermediate-sized filament protein vimentin from eye lens tissue. Chromatofocusing is applied as the sole purification step. The apparent isoelectric point of the protein in 6 M urea and at 22 degrees C is 4.9. Electrophoretic mobility on one- and two-dimensional polyacrylamide gels, solubility in 6 M urea and amino acid composition were used for identification.
Cross‐linking of neutrophil CD11b results in rapid cell surface expression of molecules required for antigen presentation and T‐cell activation (2005)

Recent studies suggest that neutrophils may play a role in antigen presentation. In support of this hypothesis it has been shown that these cells appear to contain cytoplasmic stores of molecules required for this function, i.e. major histocompatibility complex class II (DR) antigen, CD80 and CD86. In this study we have considered a mechanism for the translocation of these preformed molecules onto the cell surface which does not require active synthesis. Cross-linking of the Mac-1 molecule (CD18 + CD11b) was shown to result in rapid cell surface expression of CD80, CD86 and DR antigen on the surface of normal human peripheral blood neutrophils. A distinct subpopulation (approximately 20%) of neutrophils appeared to be enlarged and were found to express significantly elevated levels of these molecules on the cell surface following cross-linking of CD11b when compared with control cells. The level of expression of CD80, CD86 and DR antigen on these large cells was comparable to, and in some cases greater than, the levels found expressed on the surface of monocytes obtained from the same donors. In addition, these cytoplasmic molecules were shown by confocal laser microscopy and by immunoelectron microscopy to be located within secretory vesicles. Following rapid translocation onto the cell surface, CD80 and CD86 appeared to be colocalized within large clusters reminiscent of the supramolecular antigen clusters previously found on conventional antigen-presenting cells. These findings therefore lend further support for the hypothesis that neutrophils may have a role to play in antigen presentation and/or T-cell activation.
Public-key cryptography based on simple semirings (2008)

actions 2.1 Semigroup actions . . . . . .
Contribution to a generic revision of the neotropical milesinae (Diptera: Syrphidae). (2023)

A revised generic classification of the Neotropical Milesinae is proposed. Twelve tribes, six subtribes and forty-two genera are recognized and keys to these taxa are provided. Detailed descriptions of the tribes and genera, along with a discussion of the new characters used; are included. The male genitalia and some of the other principal characters for almost all the genera are figured. One new genus (Notiocheilosia, type-species Chilosia nitescens Shannon and Aubertin) is described. The following new synonymies are made: Copestylum Macquart (= Apophysophora Williston, =Megametopon Giglio-Tos, Viereckomyia Currran, =Lepidopsis Curran, =Volosyrpha Shannon and = Volucellosia Curran); Dolichogyna Macquart (=Nosodepus Speiser); Habromyia Williston (=Edwardsietta Hull, = Lycopale Hull and = Criorthrix Hull); Meromacrus Rondani (= Thalamopales Hull); and Sterphus Philippi (=Crepidomyia Shannon, =Tatuomyia Shannon, =Senoceria Hull and =Mutillimyia Hull). Copestylum Macquart is recognised for the New World species of Volucella Geoffroy. Chromocheilosia Hull and Fluke is given full genewic status and transferred from Cheilosia (Cheilosini) to the tribe Chrysogasterini. Eristalis Latreille is partitioned into Eristalis, s.s., Eoseristalis Kanervo and Palpada Macquart. Zoogeography of the Neotropical milesine fauna is discussed. The gross statistics of the fauna are compared to those of other regions and these statistics indicate a long-isolated fauna. The distributional patterns and phylogenetic relationships of the Neotropical genera are also analyzed and these patterns and relationships support a Nearctic origin for almost all of the South American milesine flies. Continental Drift and its possible effect on the Neotropical fauna is also briefly reviewed. Finally the transition between the Nearctic and Neotropical milesine faunas is examined and this transition appears to consist of predominantly Neotropical groups that have moved northward, whereas only one Nearctic group has moved southward in the transitional zone.
An Updated Review on Betacoronavirus Viral Entry Inhibitors: Learning from Past Discoveries to Advance COVID-19 Drug Discovery (2021)

Even after one year of its first outbreak reported in China, the coronavirus disease 2019 (COVID-19) pandemic is still sweeping the World, causing serious infections and claiming more fatalities. COVID-19 is caused by the novel coronavirus SARS-CoV-2, which belongs to the genus Betacoronavirus (β-CoVs), which is of greatest clinical importance since it contains many other viruses that cause respiratory disease in humans, including OC43, HKU1, SARS-CoV, and MERS. The spike (S) glycoprotein of β-CoVs is a key virulence factor in determining disease pathogenesis and host tropism, and it also mediates virus binding to the host's receptors to allow viral entry into host cells, i.e., the first step in virus lifecycle. Viral entry inhibitors are considered promising putative drugs for COVID-19. Herein, we mined the biomedical literature for viral entry inhibitors of other coronaviruses, with special emphasis on β-CoVs entry inhibitors. We also outlined the structural features of SARS-CoV-2 S protein and how it differs from other β-CoVs to better understand the structural determinants of S protein binding to its human receptor (ACE2). This review highlighted several promising viral entry inhibitors as potential treatments for COVID-19.
Quantitative <i>In Vivo</i> Analyses Reveal a Complex Pharmacogenomic Landscape in Lung Adenocarcinoma (2021)

The lack of knowledge about the relationship between tumor genotypes and therapeutic responses remains one of the most critical gaps in enabling the effective use of cancer therapies. Here, we couple a multiplexed and quantitative experimental platform with robust statistical methods to enable pharmacogenomic mapping of lung cancer treatment responses <i>in vivo</i>. The complex map of genotype-specific treatment responses uncovered that over 20% of possible interactions show significant resistance or sensitivity. Known and novel interactions were identified, and one of these interactions, the resistance of KEAP1-mutant lung tumors to platinum therapy, was validated using a large patient response data set. These results highlight the broad impact of tumor suppressor genotype on treatment responses and define a strategy to identify the determinants of precision therapies. SIGNIFICANCE: An experimental and analytical framework to generate <i>in vivo</i> pharmacogenomic maps that relate tumor genotypes to therapeutic responses reveals a surprisingly complex map of genotype-specific resistance and sensitivity.
A distinctive property of Tth DNA polymerase: enzymatic amplification in the presence of phenol. (1994)

The ability of thermostable DNA polymerases to mediate template-dependent DNA synthesis in the presence of phenol has been examined as monitored by amplification of a specific Borrelia burgdorferi rRNA sequence. Tth DNA polymerase displayed the unique property of maintaining both DNA- and RNA-dependent DNA polymerase activities in the presence of 2%-5% (vol/vol) of phenol-saturated PBS buffer. Tth DNA polymerase mediated reverse transcriptase activity was unaffected by phenol-saturated phosphate-buffered saline concentrations as high as 15% (vol/vol). By contrast, Taq DNA Polymerase was inactive under these conditions. The ability to function in the presence of phenol can greatly simplify reverse transcriptase, PCR and reverse transcription-PCR protocols since the phenol-saturated aqueous phase of a phenol partition can be added directly to the reaction mixtures. The simplicity of the procedures described should have applicability to a broad range of basic research, clinical and forensic applications.