gebhart/patrepeval huggingface dataset:
Computer augmented teacher training (1975)

A new teacher education program has been inaugurated at the University of Massachusetts' School of Education under the title "Computer Augmented Teacher Training". The CATT program places the computer in a central role--particularly the activity of programming--in order to augment the cognitive, affective, and social competencies of prospective mathematics teachers. In the cognitive domain, teachers learn <u>what</u> mathematics <u>to teach</u> as well as <u>how to teach</u> it effectively. In the affective domain, teachers enhance their <u>self-concepts</u> and build <u>self-confidence</u> by encountering both successes and failures in working with manipulative materials, self-instructional texts, and computer-related activities. Finally, in the social area, teachers raise their consciousness about the advantages and limitations of technology as they develop <u>computer literacy</u>.
Photovoltaic-STATCOM with Low Voltage Ride through Strategy and Power Quality Enhancement in a Grid Integrated Wind-PV System (2018)

The traditional configurations of power systems are changing due to the greater penetration of renewable energy sources (solar and wind), resulting in reliability issues. At present, the most severe power quality problems in distribution systems are current harmonics, reactive power demands, and the islanding of renewables caused by severe voltage variations (voltage sag and swell). Current harmonics and voltage sag strongly affect the performance of renewable-based power systems. Various conventional methods (passive filters, capacitor bank, and UPS) are not able to mitigate harmonics and voltage sag completely. Based on several studies, custom power devices can mitigate harmonics completely and slightly mitigate voltage sags with reactive power supplies. To ensure the generating units remain grid-connected during voltage sags and to improve system operation during abnormal conditions, efficient and reliable utilization of PV solar farm inverter as STATCOMs is needed. This paper elaborates the dynamic performance of a VSC-based PV-STATCOM for power quality enhancement in a grid integrated system and low voltage ride through (LVRT) capability. LVRT requirements suggest that the injection of real and reactive power supports grid voltage during abnormal grid conditions. The proposed strategy was demonstrated with MATLAB simulations.
[Topographological-anatomic changes in the structure of temporo-mandibular joint in case of fracture of the mandible condylar process at cervical level]. (2011)

Pathological changes in soft tissues surrounding the fracture site as well as in the structural elements of temporo-mandibular joint always occured in condylar process fracture with shift at cervical mandibular jaw level. Other changes were also seen in the joint on the opposite normal side. Modelling of condylar process fracture at mandibular cervical level by means of three-dimensional computer model of temporo-mandibular joint contributed to proper understanding of this pathology emergence as well as to prediction and elimination of disorders arising in adjacent to the fracture site tissues.
Hanganutziu-Deicher Antigen and Antibody in Pathologic Sera and Tissues (1979)

Heterophile, Hanganutziu-Deicher (H-D) antigen was studied in pathologic sera by means of inhibition of agglutination of bovine erythrocytes by H-D antibodies. H-D antigen was demonstrated in 38% of random cancer sera, 25% of lymphoma or leukemia sera, 25% of leprosy sera, 8% of infectious mononucleosis sera, 6% of rheumatoid arthritis sera, and 27% of synovial fluids of rheumatoid arthritis patients. None of 134 normal human sera gave positive results. Some of the inhibition-positive cancer sera formed precipitation lines with H-D antibody-containing sera. Over 50% of various extracts of cancer tissues as well as spleens of lymphoma or leukemia patients were shown to contain H-D antigen by means of the inhibition test.
A nonsense mutation (R220X) in the α-galactosidase A gene detected in a female carrier of Fabry disease (1994)

Journal Article A nonsense mutation (R220X) in the α-galactosidase A gene detected in a female carrier of Fabry disease Get access Cathy Meaney, Cathy Meaney Department of Chemical Pathology, Women's and Children's HospitalNorth Adelaide, SA 5006, Australia Search for other works by this author on: Oxford Academic PubMed Google Scholar Lianne C. Blanch, Lianne C. Blanch Department of Chemical Pathology, Women's and Children's HospitalNorth Adelaide, SA 5006, Australia Search for other works by this author on: Oxford Academic PubMed Google Scholar C.Phillip Morris C.Phillip Morris * Department of Chemical Pathology, Women's and Children's HospitalNorth Adelaide, SA 5006, Australia *To whom correspondence should be addressed Search for other works by this author on: Oxford Academic PubMed Google Scholar Human Molecular Genetics, Volume 3, Issue 6, June 1994, Pages 1019–1020, https://doi.org/10.1093/hmg/3.6.1019 Published: 01 June 1994 Article history Received: 09 March 1994 Revision received: 06 April 1994 Accepted: 06 April 1994 Published: 01 June 1994
Traceability Markers to the Botanical Origin in Olive Oils (2009)

This review provides an overview of traceability studies performed to date (April 2009) for olive oils. Special emphasis has been made on the botanical origin because high-quality monovarietal olive oils have been recently introduced on the markets and their quality control requires the development of new and powerful analytical tools as well as new regulations to avoid fraud to consumers. Several parameters with discriminant power have been used for olive oil traceability according to the olive variety used in the production of the oil. They have been considered as traceability markers to the botanical origin and classified, in this work, as compositional and genetical markers.
Body posture and face orientation estimation by convolutional network with heterogeneous learning (2018)

Autonomous driving system switches over to a manual driving mode by human when the system is not able to drive itself. The system has to constantly monitor whether the driver can drive the vehicle by the driver's posture and face orientation. Conventional methods for estimating posture and face orientation perform feature extraction and recognition for each task, and thus require an appreciable amount of processing time. In this paper, we propose a method that performs multiple tasks by Deep Convolutional Neural Network (DCNN) with heterogeneous learning, by sharing the feature extraction process. The body posture and face orientation estimation can be performed simultaneously. In evaluation, we have achieved a high accuracy of 98% in body posture estimation, and 91% in face orientation estimation. The processing time for a single image has been 2.6 ms when the we employ a GPU, and 34.1 ms in CPU. We confirm that proposed method can perform body posture and face orientation estimation in real time.
7-Deazaguanosine: Phosphoramidite and Phosphonate Building Blocks for Solid-Phase Oligoribonucleotide Synthesis (1992)

T h e synthesis of oligoribonucleotide building blocks (phosphonates and phosphoramidites) of 7-deazaguanosine (2-amino-7-(O-D-ribofuranosyl)-7~-pyrrolo[2,3-~]pyrimidin-4(3~)-one. 1) is described.Silylation of the 2'-hydroxy group of 7-deaza-gisobutyryl-5'-0-(4-monomethoxytrity1)guanosine (5) was studied with regard to the 2'-selectivity.Best results were obtained with triisopropylsilyl chloride/AgN03.The 2'4-protected intermediates (6a and 6b) were converted into the phosphonates (30, b) or methylphosphoramidites (4a, b), which were successfully used for solid-phase oligoribonucleotide synthesis of ( ~~6 -c ) ~ (9).Guanine-rich regions of nucleic acids can associate to form multi-stranded structures.Enzymatically prepared poly(G) can aggregate to four-stranded he1ices.lTetramerization of short tracts of G-residues in naturally occurring RNA has also been reported.2In the case of 2'-deoxyguanosine containing nucleic acids, so-called G ~-D N A ~ is formed.
Glutaraldehyde – A Subtle Tool in the Investigation of Healthy and Pathologic Red Blood Cells (2019)

Glutaraldehyde is a well-known substance used in biomedical research to fix cells. Since hemolytic anemias are often associated with red blood cell shape changes deviating from the biconcave disk shape, conservation of these shapes for imaging in general and 3D-imaging in particular, like confocal microscopy, scanning electron microscopy or scanning probe microscopy is a common desire. Along with the fixation comes an increase in the stiffness of the cells. In the context of red blood cells this increased rigidity is often used to mimic malaria infected red blood cells because they are also stiffer than healthy red blood cells. However, the use of glutaraldehyde is associated with numerous pitfalls: (i) while the increase in rigidity by an application of increasing concentrations of glutaraldehyde is an analog process, the fixation is a rather digital event (all or none); (ii) addition of glutaraldehyde massively changes osmolality in a concentration dependent manner and hence cell shapes can be distorted; (iii) glutaraldehyde batches differ in their properties especially in the ratio of monomers and polymers; (iv) handling pitfalls, like inducing shear artifacts of red blood cell shapes or cell density changes that needs to be considered, e.g., when working with cells in flow; (v) staining glutaraldehyde treated red blood cells need different approaches compared to living cells, for instance, because glutaraldehyde itself induces a strong fluorescence. Within this paper we provide documentation about the subtle use of glutaraldehyde on healthy and pathologic red blood cells and how to deal with or circumvent pitfalls.
Scalable I/O architecture for buses (2003)

The author discusses current IEEE activities on the P1394 bus standard (1 Mb/s) and the P1596 interconnect (1 Gb/s), which concern the definition of standard control register locations, formats, and functions. This scalable definition, called an I/O architecture, is being considered for use by other bus standards as well (P896.1 Futurebus and the P1014 VME bus standards). The scalable I/O architecture definition is bus-technology-independent, and supports large multiple-bus configurations. Several of the scalable features of the I/O architecture are described.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Impact of Cyclosporine Upon Emotional and Social Behavior in Mice (2007)

This in vivo model suggests that cyclosporine at a high dose induced hypo-function of the prefrontal cortex as a result of reduced release of serotonin and dopamine, increased anxiety-related behavior, and disturbed social behavior. Clozapine partially restored an index of social behavior. The present findings are pathologically relevant in patients who take cyclosporine.
Output-capacitorless CMOS LDO regulator based on high slew-rate current-mode transconductance amplifier (2013)

A low quiescent current output-capacitorless CMOS LDO regulator based on a high slew-rate current-mode transconductance amplifier (CTA) as an error amplifier is presented. Load transient characteristic of the proposed LDO is improved even at low quiescent currents, by using a local common-mode feedback (LCMFB) in the proposed CTA. This provides an increase in the order of transfer characteristic of the circuit, thereby enhancing the slew-rate at the gate of pass transistor. The proposed CTA-based LDO topology has been designed and post-layout simulated in HSPICE, in a 0.18 μm CMOS process to supply a load current between 0-100 mA. Postlayout simulation results reveal that the proposed LDO is stable without any internal compensation strategy and with on-chip output capacitor or lumped parasitic capacitances at the output node between 10-100 pF.
Tissue mechanics drives regeneration of a mucociliated epidermis on the surface of Xenopus embryonic aggregates (2020)

Injury, surgery, and disease often disrupt tissues and it is the process of regeneration that aids the restoration of architecture and function. Regeneration can occur through multiple strategies including stem cell expansion, transdifferentiation, or proliferation of differentiated cells. We have identified a case of regeneration in Xenopus embryonic aggregates that restores a mucociliated epithelium from mesenchymal cells. Following disruption of embryonic tissue architecture and assembly of a compact mesenchymal aggregate, regeneration first restores an epithelium, transitioning from mesenchymal cells at the surface of the aggregate. Cells establish apico-basal polarity within 5 hours and a mucociliated epithelium within 24 hours. Regeneration coincides with nuclear translocation of the putative mechanotransducer YAP1 and a sharp increase in aggregate stiffness, and regeneration can be controlled by altering stiffness. We propose that regeneration of a mucociliated epithelium occurs in response to biophysical cues sensed by newly exposed cells on the surface of a disrupted mesenchymal tissue.
Genetically Engineered T-Cells for Malignant Glioma: Overcoming the Barriers to Effective Immunotherapy (2019)

Malignant gliomas carry a dismal prognosis. Conventional treatment using chemo- and radiotherapy has limited efficacy with adverse events. Therapy with genetically engineered T-cells, such as chimeric antigen receptor (CAR) T-cells, may represent a promising approach to improve patient outcomes owing to their potential ability to attack highly infiltrative tumors in a tumor-specific manner and possible persistence of the adaptive immune response. However, the unique anatomical features of the brain and susceptibility of this organ to irreversible tissue damage have made immunotherapy especially challenging in the setting of glioma. With safety concerns in mind, multiple teams have initiated clinical trials using CAR T-cells in glioma patients. The valuable lessons learnt from those trials highlight critical areas for further improvement: tackling the issues of the antigen presentation and T-cell homing in the brain, immunosuppression in the glioma microenvironment, antigen heterogeneity and off-tumor toxicity, and the adaptation of existing clinical therapies to reflect the intricacies of immune response in the brain. This review summarizes the up-to-date clinical outcomes of CAR T-cell clinical trials in glioma patients and examines the most pressing hurdles limiting the efficacy of these therapies. Furthermore, this review uses these hurdles as a framework upon which to evaluate cutting-edge pre-clinical strategies aiming to overcome those barriers.
Software Defined Networks: A Comprehensive Approach (2014)

Software Defined Networks discusses the historical networking environment that gave rise to SDN, as well as the latest advances in SDN technology. The book gives you the state of the art knowledge needed for successful deployment of an SDN, including: How to explain to the non-technical business decision makers in your organization the potential benefits, as well as the risks, in shifting parts of a network to the SDN modelHow to make intelligent decisions about when to integrate SDN technologies in a networkHow to decide if your organization should be developing its own SDN applications or
The mitochondrial toxin 3‐nitropropionic acid induces differential expression patterns of apoptosis‐related markers in rat striatum (2001)

The mitochondrial toxin 3-nitropropionic acid (3-NP) causes selective striatal lesions in rats and serves as an experimental model for the neurodegenerative disorder Huntington's disease (HD). Apoptotic cell death has been implicated for the neuronal degeneration that occurs in HD brains. The present study was designed to investigate whether the 3-NP-induced cell death in rats involves apoptosis and an altered expression of Bcl-2 family proteins. Systemic administration of 3-NP via subcutaneous Alzet pumps resulted in lesions of variable severity with neuronal loss and gliosis in the striatum. Using the terminal transferase-mediated biotinylated-UTP nick end-labelling (TUNEL) of DNA, TUNEL-positive cells exhibiting typical apoptotic morphology were detected only in the striatum of rats with a severe lesion. Furthermore, the neuronal expression of the pro-apoptotic protein Bax was strongly increased in the core of the severe lesion. Expression of the anti-apoptotic marker Bcl-2 was unchanged in this location, but was enhanced in the margins of the lesions. A moderately increased expression of both Bax and Bcl-2 was observed in dark neurones in the mild lesion and in the subtle lesion. The presence of nuclear DNA fragmentation, strong granular Bax expression and an increased Bax/Bcl-2 ratio in the centre of severe lesions suggests the occurrence of apoptotic cell death following 3-NP administration. In contrast, the dark compromised neurones observed in 3-NP-treated animals revealed an equally enhanced expression of both Bax and Bcl-2, but lacked TUNEL-labelling, and are therefore not apoptotic.
Three-dimensional speckle-noise reduction by using coherent integral imaging (2009)

We present a 3D imaging method to reduce speckle noise that exists in coherent imaging systems. This approach is based on integral imaging (II). The elemental images set having speckle-noise patterns of a 3D object is obtained by II technique under coherent illumination. The computational geometrical ray-propagation algorithm is applied to the elemental images in order to reconstruct the original 3D object. A uniform probability-density function is assumed for modeling the phase distribution of the speckle patterns. The statistical point estimator is used for 3D speckle removal. Speckle index is calculated to compare the computational reconstruction using the proposed method with that of conventional coherent image degraded by speckle patterns for 3D object reconstruction and by object recognition. Experimental results are presented. The speckle index, mean square error, and signal-to-noise ratio are used as performance metrics and are shown to have been significantly improved by the proposed method to reduce speckle noise in the 3D object reconstruction. 3D reconstruction experiments of objects with reduced speckle noise are presented. To the best of our knowledge, this is the first report on 3D speckle removal using II and statistical estimation algorithms.
Highly organised and dense vertical silicon nanowire arrays grown in porous alumina template on <100> silicon wafers (2013)

In this work, nanoimprint lithography combined with standard anodization etching is used to make perfectly organised triangular arrays of vertical cylindrical alumina nanopores onto standard <100>-oriented silicon wafers. Both the pore diameter and the period of alumina porous array are well controlled and can be tuned: the periods vary from 80 to 460 nm, and the diameters vary from 15 nm to any required diameter. These porous thin layers are then successfully used as templates for the guided epitaxial growth of organised mono-crystalline silicon nanowire arrays in a chemical vapour deposition chamber. We report the densities of silicon nanowires up to 9 × 109 cm-2 organised in highly regular arrays with excellent diameter distribution. All process steps are demonstrated on surfaces up to 2 × 2 cm2. Specific emphasis was made to select techniques compatible with microelectronic fabrication standards, adaptable to large surface samples and with a reasonable cost. Achievements made in the quality of the porous alumina array, therefore on the silicon nanowire array, widen the number of potential applications for this technology, such as optical detectors or biological sensors.
Tailoring Cellulose Surfaces by Controlled Polymerization Methods (2013)

Abstract Cellulose, with its excellent mechanical properties and low weight, would be highly advantageous to employ in bioplastics and biocomposites applications. However, to expand the utilization of cellulose beyond its traditional uses, a modification of the fiber surface is often a prerequisite. One approach is to graft polymer chains on the surface in order to compatibilize the fibers with a non‐polar polymer matrix or to introduce functionalities. By exploiting controlled polymerization methods such as ATRP, RAFT, ROP, and ROMP, the surface of the fibers can be carefully tailored. Herein, an overview on controlled, heterogeneous grafting of cellulose fibers and fibrils employing both “grafting from” and “grafting to” methodologies is provided, focusing on the latest findings magnified image .
Differential expression of diacylglycerol acyltransferase (<i>DGAT</i>) genes in olive tissues (2000)

Fatty acids are accumulated in triacylglycerols (TAGs), in specialized organelles of seeds named oil bodies. The major site of TAG accumulation is detected in developing seed and mesocarp of certain species. We have isolated two cDNAs encoding DGAT enzymes from olives. The deduced polypeptides differ by 26 amino acids in size. However, they have high homology and almost identical hydropathy profiles. The DGAT gene is expressed in all tissues that synthesize TAGs. However, higher levels of DGAT transcripts have been detected in seed tissues of developing olive drupe. DGAT expression and mRNA accumulation in drupe tissues is developmentally regulated. Each DGAT transcript shows a distinct profile of accumulation. The existence of two different DGAT transcripts might reflect two different enzymes with discrete function and/or localization.
Characterization of hepatitis B virus capsid particle assembly in Xenopus oocytes (1992)

Little is known about the assembly of the 28-nm nucleocapsid or core particle of hepatitis B virus. Here we show that this assembly process can be reconstituted in Xenopus oocytes injected with a synthetic mRNA encoding the hepatitis B virus capsid protein (p21.5). Injected oocytes produce both a nonparticulate p21.5 species (free p21.5) and capsid particles. We describe rapid and simple methods for fractionating these species on a small scale either with step gradients of 10 to 60% (wt/vol) sucrose or by centrifugation to pellet the particles, and we characterize the oocyte core particles. Free p21.5 exhibits chemical and physical properties distinctly different from those of particles. Free p21.5 is partially cleaved by proteinase K, whereas core particles are almost completely resistant to cleavage. This suggests that the carboxyl-terminal protamine region, the main target for proteases within p21.5, is exposed in free p21.5 but faces the interior of the p21.5 core particle. Finally, pulse-chase experiments demonstrated that free p21.5 can be chased almost quantitatively into core particles, establishing that free p21.5 is fully competent to form particles and represents an assembly intermediate on the pathway for core particle formation. However, core particle assembly appears very dependent on p21.5 concentration and is rapidly compromised if the p21.5 concentration is lowered. The advantages of oocytes for studying assembly are discussed.