gebhart/patrepeval huggingface dataset:
Inhibitors of Protein Tyrosine Kinase pp<sup>60<sup>v-src</sup></sup>: Sterol Sulfates from the Brittle Star Ophiarachna incrassata (1994)

Bioactivity-guided fractionation of the extracts of the green brittle star Ophiarachna incrassata using a protein tyrosine kinase pp60v-src inhibition assay led to the isolation of a new sterol sulfate [2] together with four known ones (1,3-5). All five compounds were found to inhibit protein tyrosine kinase pp 60v-src.
Like dissolves like: A first-principles theory for predicting liquid miscibility and mixture dielectric constant (2021)

Liquid mixtures are ubiquitous. Miscibility and dielectric constant are fundamental properties that govern the applications of liquid mixtures. However, despite their importance, miscibility is usually predicted qualitatively based on the vaguely defined polarity of the liquids, and the dielectric constant of the mixture is modeled by introducing mixing rules. Here, we develop a first-principles theory for polar liquid mixtures using a statistical field approach, without resorting to mixing rules. With this theory, we obtain simple expressions for the mixture's dielectric constant and free energy of mixing. The dielectric constant predicted by this theory agrees well with measured data for simple binary mixtures. On the basis of the derived free energy of mixing, we can construct a miscibility map in the parameter space of the dielectric constant and molar volume for each liquid. The predicted miscibility shows remarkable agreement with known data, thus providing a quantitative basis for the empirical "like-dissolves-like" rule.
A Common Framework for Interactive Texture Transfer (2018)

In this paper, we present a general-purpose solution to interactive texture transfer problems that better preserves both local structure and visual richness. It is challenging due to the diversity of tasks and the simplicity of required user guidance. The core idea of our common framework is to use multiple custom channels to dynamically guide the synthesis process. For interactivity, users can control the spatial distribution of stylized textures via semantic channels. The structure guidance, acquired by two stages of automatic extraction and propagation of structure information, provides a prior for initialization and preserves the salient structure by searching the nearest neighbor fields (NNF) with structure coherence. Meanwhile, texture coherence is also exploited to maintain similar style with the source image. In addition, we leverage an improved PatchMatch with extended NNF and matrix operations to obtain transformable source patches with richer geometric information at high speed. We demonstrate the effectiveness and superiority of our method on a variety of scenes through extensive comparisons with state-of-the-art algorithms.
Method and system for robot end effector path correction using 3-D ultrasound sensors (2002)

A method and system for correcting a preprogrammed robot end effector path to reduce the kinematic error are developed. The approach used in the method is to mount 3D ultrasound position sensor on the robot end effector and compute 3D Cartesian position of this sensor using 1D range measurements between the senders and an array of ultrasound receivers at fixed, predetermined positions. The method and system allow speedy correction of a robot path with economical usage of computer resources. The method includes steps of sensing and measuring path offsets between the idealized end effector location and the actual location of the manipulator end effector at a plurality of waypoints. Then, after appropriate calculations, the method includes the steps of correcting the coordinates of waypoints within the preprogrammed path, transforming the preprogrammed path coordinates into machine control coordinates, and providing a controller for the robot manipulator with such machine control coordinates. A 3D ultrasound position sensor used in the method provides low-cost, high precision measurements of the Cartesian position of a robot end effector within the robot workspace.
Polymeric Materials for Corrosion Control (1986)

Polymeric materials are widely used to control the corrosion of metals, both to maintain appearance and to prevent loss of structural integrity. In this chapter, the fundamentals of metallic corrosion are briefly reviewed. Methods of studying corrosion, and of evaluating the performance of polymeric materials used in corrosion protection, are outlined. Factors that influence the corrosion protective performance of polymeric materials are discussed, and some of the research needs and important unsolved problems are highlighted.
Alteraciones iniciales inducidas en los vasos placentarios de la rata por el virus de la encefalitis equina venezolana (1983)

Los virus de la rubeola y de la EEV pertenecen ambos a la familia Togaviridae. Las alteraciones iniciales en los vasos placentarios durante la infeccion con el virus de la EEV fueron examinados por metodos virologicos, histologicos e inmunohistoquimicos. Se vieron celulas citotrofoblasticas que reemplazan a las celulas endoteliales y mostraban signos de inflamacion y evidencia inmunohistoquimica de antigenos del virus de la EEV en ellas y en las celulas deciduales perivasculares. La comparacion de los hallazgos virologicos y morfologicos en la infeccion placentaria con el virus de la EEV en la rata y el mecanismo petrogenetico propuesto para explicar el dano intrauterino inducido en los seres humanos por el virus de la rubeola, demuestra grandes similitudes. Se propone una cuidadosa evaluacion del papel del virus de la EEV como causa de malformaciones congenitas en las areas endemicas de esta infeccion en Venezuela.
Myocardial contusion caused by a baseball (1996)

Myocardial contusion is a rare type of sports injury. We report a case of myocardial contusion caused by a baseball. In this patient, arrhythmias were induced by an exercise test 1 week after injury. That patients with myocardial contusion but without arrhythmias at rest need to be treated carefully is emphasized.
A Survey of Lower-than-Best-Effort Transport Protocols (2011)

This document provides a survey of transport protocols which are
designed to have a smaller bandwidth and/or delay impact on standard
TCP standard TCP itself when they share a bottleneck with it.
Such protocols could be used for low-priority background traffic, as
they provide what is sometimes called a less than (or lower than)
best-effort service.
Convolutional Sequence Modeling Revisited (2018)

This paper revisits the problem of sequence modeling using convolutional architectures. Although both convolutional and recurrent architectures have a long history in sequence prediction, the current mindset in much of the deep learning community is that generic sequence modeling is best handled using recurrent networks. The goal of this paper is question this assumption. Specifically, we consider a simple generic temporal convolution network (TCN), which adopts features from modern ConvNet architectures such as a dilations and residual connections. We show that on a variety of sequence modeling tasks, including many frequently used as benchmarks for evaluating recurrent networks, the TCN outperforms baseline RNN methods (LSTMs, GRUs, and vanilla RNNs) and sometimes even highly specialized approaches. We further show that the potential infinite memory advantage that RNNs have over TCNs is largely absent in practice: TCNs indeed exhibit longer effective history sizes than their recurrent counterparts. As a whole, we argue that it may be time (re)consider ConvNets as the default go to architecture for sequence modeling.
Ligands for the alkali metals. Part 3. Further examples of nitrogen-containing ‘crown’ compounds (1977)

An unambigous route from o-aminophenol to dibenzo-crowns with two secondary amine links is reported. Some new mono- and di-nitrogen-containing monobenzo-crowns have also been prepared. The simple mononitrogencontaining crowns can be modified by N-substitution, with, for example, a pendant donor group, sufficiently flexible to co-ordinate to metals held in a polyether ring.
Cross-linking of Promoter DNA to T7 RNA Polymerase Does Not Prevent Formation of a Stable Elongation Complex (2004)

T7 RNA polymerase recognizes a small promoter, binds DNA, and begins the process of transcription by synthesizing short RNA products without releasing promoter contacts. To determine whether the promoter contact must be released to make longer RNA products and at what position the promoter must be released, a mutant RNA polymerase was designed that allows cross-linking to a modified promoter via a covalent disulfide bond. The modifications individually have no measurable effect on transcription. Under oxidizing conditions that produce the protein-DNA cross-link, the complex is able to synthesize short RNA products, strongly supporting a model in which promoter contacts are not lost on translocation through at least position +6. However, cross-linked complexes are impaired in promoter escape in that only about one in four can escape to make full-length RNA. The remainder release 12- and 13-mer RNA transcripts, suggesting an increased energetic barrier in the transition from an initial transcribing complex to a fully competent elongation complex. The results are discussed in the context of a model in which promoter release helps drive initial collapse of the upstream edge of the bubble, which, in turn, drives initial displacement of the 5'-end of the RNA.
A rapid seamless method for gene knockout in Pseudomonas aeruginosa (2017)

This method from the construction of the suicide vector to sequence confirmation of the unmarked gene deletion can be performed in one week, without the requirement for expensive proprietary reagents or instruments. The precision of Gibson assembly and the fact the accuracy in generating the desirable construct is 95%, makes this a viable and attractive alternative to previous methods.
Structural Control of Sand Bodies and Deep Exploration for Oil and Gas (2002)

The structural styles can be used to analyses and predict developments and distributions of sand bodies in a rift basin. The dynamic process of faulting and sedimentation can be expressed as follow: the basin topography controlled by fault activity can control water dynamics; which in turn affect the transport and sedimentation of sediments. The corresponding analysis between structural styles and sand depositional types includes the following aspects: (1) in section, the corresponding between development of fault terraces and sand depositional types; (2) in plane, the relationship between faults' association and distributions of sand bodies. There are four types of terrace styles to be identified. They are Steep Slope Single Fault Terrace (SSSFT), Steep Slope Multiple Fault Terrace (SSMFT), Gentle Slope (GS) and Gentle Slope Multiple Fault Terrace (GSMFT), which also can be divided into six subtypes by the timing of the faults activities and the directions of their activity migrations (basinward and landward or marginward). They correspond to the following sand depositions such as alluvial fan, fan delta and turbidite fan etc.. The analysis of structure-sedimentation is a discussion on the rank Ⅲ sequence evolution under the condition of pulsing or episodic fault activities. It has been recognized four plane fault associations such as the comb, the broom, the fork and the fault-fold association as well as the corresponding sand distributions. Structural-sedimentary models above mentioned are significant for the deep oil and gas exploration when lacking of the drill data. It may reduce multiple resolutions in the interpretation of seismic-sedimentary facies and promote sand predictions through the constraints of the structural styles of the basin units. The structural-sedimentary pattern can be used as a geological model in oil and gas exploration in the rift basins.
Catalytic Effects of Chlorate Ions on the Electrode Reaction Processes of 12-Molybdophosphate and 12-Molybdosilicate (1984)

Abstract The third cathodic waves corresponding to the reduction processes from the four-electron to the six-electron reduction products of both 12-molybdophosphate and 12-molybdosilicate are catalytic in nature in the presence of chlorate ions. The six-electron reduction product of 12-molybdophosphate is oxidized by chlorate ions more rapidly than that of 12-molybdosilicate.
Demand for Rarity: Evidence from a Collectible Good* (2022)

Markets for art, coins and other collectibles, culinary delicacies and eco‐tourism suggest that consumers value the rarity of many goods. While empirical evidence supports higher prices for rare goods, isolating the value of rarity has proven difficult. I analyze prices for a collectible card game and show goods that are designated as rare trade at higher prices than functionally equivalent substitutes. Importantly, I use novel features of this market to account for scarcity, observed and unobserved product characteristics and separately identify rarity effects. These results have important implications for markets ranging from luxury goods to conservation of endangered species.
Automated generation of custom pad cells for ASICs (2002)

A CMOS pad cell generator has been developed to create layouts of custom pads in any set of customer-provided design rules. This generator is intended primarily for customer-owned design. Customer-owned ASICs (application-specific integrated circuits) often suffer from reliability problems because of poor ESD (electrostatic discharge) and latchup protection on I/O structures. These layout and process sensitive issues are usually not optimized by the designers for the foundry's fabrication capabilities. Module generation effectively solves this problem by allowing the foundry to create design rule updatable pad cells tailored for its process so as to meet industry standards for input protection.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Prevalence of Self-Reported Erectile Dysfunction in People With Long-Term IDDM (1996)

These data suggest that tighter glycemic control and careful selection of antihypertensive medications might prove beneficial.
Long-term clinical outcome of primary progressive MS: Predictive value of clinical and MRI data (2005)

The authors sought to identify clinical and MRI predictors of outcome in primary progressive multiple sclerosis (PPMS). Clinical and MRI assessments were performed at baseline and 2 and 5 years (clinical only). At baseline, disease duration, expanded disability status scale (EDSS) and brain volume predicted outcome. Adding short-term change variables, baseline EDSS, changes in T2* lesion load and cord area, and number of new lesions were predictive. Clinical and MRI variables predict long-term outcome in PPMS.
Phytotherapy in the treatment of benign prostatic hyperplasia (1998)

There are numerous plant extracts that have been used for the treatment of benign prostatic hyperplasia and voiding dysfunction. While some extracts show promise, their efficacy has not been adequately proven in long‐term, double‐blind, placebo‐controlled trials. In addition, the mechanism of action remains poorly defined.
小虫快跑 大众甲壳虫性能版 Beetle (2014)

小李：甲壳虫性能版车型新车售价为33万元,面向全球限量推出3500台,在国内限量销售50台。这款是甲壳虫传奇车型Yellow/Black Racer的复刻车型,继承了前辈个性鲜明的外观及动感的性能表现。在上个世纪70年代性能版的基础上,重新进行了系统的诠释,使之更符合当代审美标准。
Status report from the American Acne & Rosacea Society on medical management of acne in adult women, part 1: overview, clinical characteristics, and laboratory evaluation. (2015)

Acne presenting in adult women is commonly encountered in clinical practice. Many affected women have had acne during their teenaged years, have tried several therapies in the past, and are seeking effective treatment. Others are frustrated by the inexplicable emergence of acne as an adult when they never had it as a teenager. Both groups seek an explanation of why they have acne, are often psychosocially affected by its effects on appearance and self-esteem, and all are wanting effective and safe treatment. Clinicians are encouraged to connect favorably with each patient through careful history and physical examination and to consider underlying causes of androgen excess. Practical approaches to examination and laboratory evaluation are discussed.
Characteristics of Micro‐Nano Bubbles and Potential Application in Groundwater Bioremediation (2014)

Content of oxygen in water is a critical factor in increasing bioremediation efficiency for contaminated groundwater. Micro-nano bubbles (MNBs) injection seems to be an effective technique for increasing oxygen in water compared with traditional air sparging technology with macrobubbles. Micro-nano bubbles have larger interfacial area, higher inner pressure and density, and lower rising velocity in water, superior to that of macrobubbles. In this paper, MNBs with diameters ranging from 500 nm to 100 microm are investigated, with a specific focus on the oxygen mass transfer coefficient from inner bubbles to surrounding water. The influence of surfactant on the bubbles formation and dissolution is studied as well. The stability of MNBs is further investigated by means of zeta potential measurements and rising velocity analysis. The results show that MNBs can greatly increase oxygen content in water. Higher surfactant concentration in water will decrease the bubbles size, reduce the dissolution rate, and increase the zeta potential. Moreover, MNBs with greater zeta potential value tend to be more stable. Besides, the low rising velocity of MNBs contributes to the long stagnation in water. It is suggested that micro-nano bubble aeration, a potential in groundwater remediation technology, can largely enhance the bioremediation effect.
Oryzines A & B, Maleidride Congeners from Aspergillus oryzae and Their Putative Biosynthesis (2018)

<i>Aspergillus oryzae</i> is traditionally used in East Asia for the production of food and brewing. In addition, it has been developed into a suitable host for the heterologous expression of natural product biosynthetic genes and gene clusters, enabling the functional analysis of the encoded enzymes. <i>A. oryzae</i> shares a 99.5% genome homology with <i>Aspergillus flavus</i>, but their secondary metabolomes differ significantly and various compounds unique to <i>A. oryzae</i> have been reported. While using <i>A. oryzae</i> as a host for heterologous expression experiments we discovered two new metabolites in extracts of <i>A. oryzae</i> M-2-3 with an unusual maleidride backbone, which were named oryzine A and B. Their structures were elucidated by high resolution mass spectrometry (HRMS) and nuclear magnetic resonance (NMR) analysis. Their structural relationships with known maleidrides implied involvement of a citrate synthase (CS) and a polyketide (PKS) or fatty acid synthase (FAS) in their biosynthesis. Analysis of the <i>A. oryzae</i> genome revealed a single putative biosynthetic gene cluster (BGC) consistent with the hypothetical biosynthesis of the oryzines. These findings increase knowledge of the chemical potential of <i>A. oryzae</i> and are the first attempt to link a novel product of this fungus with genomic data.
Workflow in different styles of virtual enterprise (2001)

Because of the many forms a Virtual Enterprise (VE) can take, there is no single model of what type of approach to workflow management is most appropriate. This paper is based on an analysis of the different types of business practice that lead to the formation of VEs. A number of different workflow scenarios are depicted, and four specific issues are then discussed. The first is the recognition of the different life cycle stages of a Virtual Enterprise. The second is the problem of workflow case identifiers across organizational boundaries. The third is the need or otherwise for shared databases to support the different scenarios. The fourth is the question of the protocol for passing work in loosely-coupled workflows. Some ideas for future work are finally proposed.
Photoconstructs of Nerve Guidance Prosthesis Using Photoreactive Gelatin as a Scaffold (2003)

We devised a novel nerve prosthesis composed of an elastomeric gelatinous tube and multifilament gelatinous fibers, both of which were prepared from styrene-derivatized gelatin, which allows in situ formation of a bioactive substance-incorporated gel. An in vitro study showed that the axonal regeneration potential of a photocured gelatin layer impregnated with laminin, fibronectin, and NGF was almost comparable with that of coated Matrigel. A nerve conduit and fibers prepared from photoreactive gelatin was subjected to visible-light irradiation with rotation in the presence of camphorquinone as a photoinitiator using a custom-designed apparatus. A sample of transparent gelatinous conduit with an inner diameter of 1.2 mm and a wall thickness of 0.6 mm and gelatin fibers ranging from 10 to 100 pm in diameter were produced. The photocured elastomeric gelatinous tube was flexible and had structural integrity that allowed mechanical handling without breaking. A novel nerve guidance prosthesis composed of tubes packed with fibers was assembled. This photofabrication technology may enable the design of a tailor-made shape and rapid morphogenesis and functional recovery of damaged nerve tissue.
Enhancing the Automation of GUI Testing (2019)

GUI testing is one of the most important and significant testing approaches among all different software testing techniques. Most software errors are captured and detected through the software GUI layer. Manual testing for GUIs has its problems. It lacks in capturing all different cases and takes a huge time from the software tester to plan, design and re-design the testing suites in case of UI change. Old techniques in the area of test-case generation are not fully-automated or dependent on human inputs. This paper presents a test-case generation model to build a testing suite for webpages using its HTML file. The proposed model has two branches. The first one focuses on generating test cases for each web-element individually based on its type. The other branch focuses on generating test cases based on different paths between web-elements in the same webpage. It is also concerned with eliminating redundant test-cases using a supervised learning, feed-forward, dynamic artificial neural network that changes number of inputs according to generated cases per web page. The proposed system has been evaluated using several datasets. Results show a significant enhancement in the test-case generation procedure.