gebhart/patrepeval huggingface dataset:
Multimodal adaptive optics retinal imager: design and performance (2012)

Optical coherence tomography (OCT) and scanning laser ophthalmoscopy (SLO) are complementary imaging modalities, the combination of which can provide clinicians with a wealth of information to detect retinal diseases, monitor disease progression, or assess new therapies. Adaptive optics (AO) is a tool that enables correction of wavefront distortions from ocular aberrations. We have developed a multimodal adaptive optics system (MAOS) for high-resolution multifunctional use in a variety of research and clinical applications. The system integrates both OCT and SLO imaging channels into an AO beam path. The optics and hardware were designed with specific features for simultaneous SLO/OCT output, for high-fidelity AO correction, for use in humans, primates, and small animals, and for efficient location and orientation of retinal regions of interest. The MAOS system was tested on human subjects and rodents. The design, performance characterization, and initial representative results from the human and animal studies are presented and discussed.
Enhancement of Robustness of Image Watermarks Image Watermark into Colored Image, Based on WT and DCT (2000)

This research is concerned with the watermarking technique which embeds image data invisibly into colored image based on Wavelet Transform (WT) and Discrete Cosine Transform (DCT) so that the watermark data be not impaired in compression, filtering, cropping, rescaling, re-sampling, and other digital manipulations.The suggested method comprises the steps of transforming the target image using WT, transforming a image watermark using DCT, integrating the wavelet transformed digital image with the DCT-transformed watermark image to embed the fingerprint into the intellectual property, and generating the watermarked image using inverse wavelet transform.In the experiments, it was found that the suggested method is highly effective against impairment of the watermark that would otherwise be caused by the image processing operations, such as compression, filtering, re-sampling, rotation, and cropping
Game of Drones - Detecting Streamed POI from Encrypted FPV Channel (2018)

Drones have created a new threat to people's privacy. We are now in an era in which anyone with a drone equipped with a video camera can use it to invade a subject's privacy by streaming the subject in his/her private space over an encrypted first person view (FPV) channel. Although many methods have been suggested to detect nearby drones, they all suffer from the same shortcoming: they cannot identify exactly what is being captured, and therefore they fail to distinguish between the legitimate use of a drone (for example, to use a drone to film a selfie from the air) and illegitimate use that invades someone's privacy (when the same operator uses the drone to stream the view into the window of his neighbor's apartment), a distinction that in some cases depends on the orientation of the drone's video camera rather than on the drone's location. In this paper we shatter the commonly held belief that the use of encryption to secure an FPV channel prevents an interceptor from extracting the POI that is being streamed. We show methods that leverage physical stimuli to detect whether the drone's camera is directed towards a target in real time. We investigate the influence of changing pixels on the FPV channel (in a lab setup). Based on our observations we demonstrate how an interceptor can perform a side-channel attack to detect whether a target is being streamed by analyzing the encrypted FPV channel that is transmitted from a real drone (DJI Mavic) in two use cases: when the target is a private house and when the target is a subject.
A 200 MHz 0.25 W packet audio terminal processor for voice-over-internet protocol applications (2002)

Voice-over-internet protocol (VoIP) terminals used in business phone, speakerphone and wireless applications require a low-power integrated solution suitable for the limited chassis area of these devices. This 200 MHz VoIP terminal processor is implemented in a 0.18 /spl mu/m 5-metal-layer CMOS process with 2 Mb of SRAM. The chip contains 16 M transistors in a 6.35/spl times/6.35 mm/sup 2/ die. This processor chip implements a complete VoIP terminal solution from raw digitized handset audio samples to compressed internet protocol (IP) packetized media independent interface (MII) signals.
Implementation of All-Optical Logic AND using XGM based on Semiconductor Optical Amplifiers (2006)

By using two input signals of A and B, an all-optical AND gate that utilize a XGM in semiconductor optical amplifiers is demonstrated at 10 Gbps. By achieving this experiment, it will be also explored the possibilities for the enhanced complex logic.
Reducing the processing time of the hierarchical watermark detector when applied to unmarked images (2006)

In this paper, we improve the performance of the hierarchical detector we proposed in [1] for real-time software or low-cost hardware implementation. Although the original hierarchical detector is faster than sub-sampled brute force-base detector when processing marked images, it unnecessarily continues to process unmarked images looking for a watermark that is not present. This processing is time-consuming; hence, it represents a significant deployment obstacle. The improved detector, however, avoids most of the processing of the unmarked areas of an image by exploiting the presence of a reference signal usually included with the embedded watermark. This reference signal enables the detector to synchronize the image after it has been subjected to a geometric transformation (scaling, rotation, and translation). The improved detector refrains from searching an image area any further whenever the level of the reference signal is very weak or the estimated scale factors and rotation angles associated with this reference signal are not consistent among the processed blocks within the same layer in the hierarchy. The proposed detector has been implemented, and the experimental results indicate that the proposed detector is computationally more efficient with unmarked images, while achieving a detection rate similar to that of the original hierarchical detector.
Solubilized Amnion Membrane Hyaluronic Acid Hydrogel Accelerates Full-Thickness Wound Healing (2017)

The early and effective treatment of wounds is vital to ensure proper wound closure and healing with appropriate functional and cosmetic outcomes. The use of human amnion membranes for wound care has been shown to be safe and effective. However, the difficulty in handling and placing thin sheets of membrane, and the high costs associated with the use of living cellularized tissue has limited the clinical application of amniotic membrane wound healing products. Here, we describe a novel amnion membrane-derived product, processed to result in a cell-free solution, while maintaining high concentrations of cell-derived cytokines and growth factors. The solubilized amnion membrane (SAM) combined with the carrier hyaluronic acid (HA) hydrogel (HA-SAM) is easy to produce, store, and apply to wounds. We demonstrated the efficacy of HA-SAM as a wound treatment using a full-thickness murine wound model. HA-SAM significantly accelerated wound closure through re-epithelialization and prevented wound contraction. HA-SAM-treated wounds had thicker regenerated skin, increased total number of blood vessels, and greater numbers of proliferating keratinocytes within the epidermis. Overall, this study confirms the efficacy of the amnion membrane as a wound treatment/dressing, and overcomes many of the limitations associated with using fresh, cryopreserved, or dehydrated tissue by providing a hydrogel delivery system for SAM. Stem Cells Translational Medicine 2017;6:2020-2032.
Bridging the Gap between Automated Manufacturing of Fuel Cell Components and Robotic Assembly of Fuel Cell Stacks (2019)

Recently demonstrated robotic assembling technologies for fuel cell stacks used fuel cell components manually pre-arranged in stacks (presenters). Identifying the original orientation of fuel cell components and loading them in presenters for a subsequent automated assembly process is a difficult, repetitive work cycle which if done manually, deceives the advantages offered by either the automated fabrication technologies for fuel cell components or by the robotic assembly processes. We present for the first time a robotic technology which enables the integration of automated fabrication processes for fuel cell components with a robotic assembly process of fuel cell stacks into a fully automated fuel cell manufacturing line. This task uses a Yaskawa Motoman SDA5F dual arm robot with integrated machine vision system. The process is used to identify and grasp randomly placed, slightly asymmetric fuel cell components, to reorient them all in the same position and stack them in presenters in preparation for a subsequent robotic assembly process. The process was demonstrated as part of a larger endeavor of bringing to readiness advanced manufacturing technologies for alternative energy systems, and responds the high priority needs identified by the U.S. Department of Energy for fuel cells manufacturing research and development.
Induction of protective immunity against Schistosoma mansoni by a nonliving vaccine. IV. Fractionation and antigenic properties of a soluble adult worm immunoprophylactic activity. (1986)

An aqueous buffer-soluble, nonparticulate fraction of adult Schistosoma mansoni worms (SWAP) was separated by gel filtration on Ultragel AcA-34, and portions of the eluate were tested for their capacity to induce protective immunity against cercarial challenge when administered intradermally to mice in combination with the adjuvant BCG. All of the immunogenic activity was found in a single peak of protein excluded in the void volume of the column. This same fraction was determined by SDS-PAGE and Western immunoblotting to be unique in that it contained a component of Mr (X 10(-3) 97 (97,000) recognized monospecifically by antibodies from mice vaccinated with unseparated SWAP plus BCG. Similarly, the protective fraction was unique in possessing the capacity to elicit 24 hr delayed footpad swelling responses, as well as lymphokine production, in SWAP-BCG-immunized mice. These results suggest that the immunogenic activity of SWAP resides in a restricted population of molecules, and possibly in the 97,000 antigen detected with antibodies from vaccinated animals. Because both the protective capacity of unfractionated SWAP and the serologic reactivity of the 97,000 antigen are sensitive to digestion with protease, it is likely that the immunologic activity of these molecules is dependent on peptide-bonded structural elements.
Adaptive Suppression of Noise in Voice Communications (2003)

A subsystem for the adaptive suppression of noise in a voice communication system effects a high level of reduction of noise that enters the system through microphones. The subsystem includes a digital signal processor (DSP) plus circuitry that implements voice-recognition and spectral- manipulation techniques. The development of the adaptive noise-suppression subsystem was prompted by the following considerations: During processing of the space shuttle at Kennedy Space Center, voice communications among test team members have been significantly impaired in several instances because some test participants have had to communicate from locations with high ambient noise levels. Ear protection for the personnel involved is commercially available and is used in such situations. However, commercially available noise-canceling microphones do not provide sufficient reduction of noise that enters through microphones and thus becomes transmitted on outbound communication links.
Synthesis, aggregation behavior and nonlinear absorption properties of lead phthalocyanines substituted with siloxane chains (2003)

The synthesis and characterization of polysiloxane substituted metal-free and lead phthalocyanines are described. These materials form a class of isotropic liquid phthalocyanines that combine a large nonlinear absorption with an exceptionally large nonlinear thermal refractive effect. These materials effectively couple the nonlinear absorption characteristics of the phthalocyanine (Pc) moiety with the thermorefractive properties typical of siloxanes. The room temperature index of these phthalocyanines can be varied by the choice of the siloxane substituent. Furthermore, the siloxane substituents are effective at inhibiting aggregation of the phthalocyanine rings. The observed aggregation constants in toluene solutions are very small and only a small degree of aggregation is observed even in the pure liquid phthalocyanines. Nonlinear transmission, z-scan, transient absorption and degenerate four-wave mixing studies confirm that the Pb substituted materials possess a broad spectral region of induced absorption with nonlinear absorption coefficients similar to that observed from other lead substituted phthalocyanines. The observed ground state molar absorption coefficients of the siloxy phthalocyanines are somewhat smaller than comparable alkyl substituted phthalocyanines. Taken together, these properties make these materials very useful for practical nonlinear optical applications. The coupling of siloxane chains to the Pc rings represents a promising way to achieve some important properties that are difficult to achieve by other means.
Parallel polarization state generation and measurement with a single metasurface (Conference Presentation) (2019)

In polarimetry, that is, a measurement of the four-component polarization Stokes vector, a measurement must either consist of four (or more) sequential intensity measurements, sacrificing time resolution, or contain four separate light paths each with separate polarization optics, increasing bulk, cost, and system complexity. Similar issues present difficulty across polarization optics technology. Metasurfaces, nanophotonic arrays of phase shifting elements, have emerged as a novel platform for polarization optics. These individual phase shifters can be designed with a characteristic anisotropy, and are thus imbued with tunable shape birefringence. A metasurface, then, can function as a subwavelength spaced array of nanoscale waveplates. I will describe how, through relatively simple optimization methods, a metasurface producing arbitrarily specified polarization states (when illuminated with light of a known polarization) can be designed. This functionality is equivalent to a traditional diffraction grating with individual waveplate optics on each order; here, all the necessary polarization optics can be integrated into a flat, ultrathin optical element. Moreover, such a metasurface can be used in a reverse configuration as a parallel snapshot polarimeter with no need for additional polarization optics (save for a single polarizer). I present a detailed experimental characterization of both concepts in the visible spectral region and a comparison of the performance of the metasurface to a commercially available rotating waveplate polarimeter. With no bulk birefringent crystal optics, a parallel, full-polarization state measurement can be made with an integrated, scalable, and inexpensive device. Given its diffractive nature, the design naturally extends to spectropolarimetry and polarization imaging.
The use of glycan serum biomarkers for the detection of cancer (2006)

A42 The Use of Glycan Serum Biomarkers for the Detection of CancerSuzanne Miyamoto 1 , Hyun Joo An 2 , Crystal Kirmiz 2 , Bensheng Li 2 , Caroline Chu 2 , Hao Liu 2 , Anthony Ferrige 4 , Robert Alecio 4 , Helen Chew 1 , Gary Leiserowitz 3 , Ralph deVere White 1 , Kit S Lam 1 and Carlito B Lebrilla 2 . 1 UC Davis Cancer Center, Sacramento, CA; 2 UC Davis, Davis, CA; 3 UC Davis Medical Center, Sacramento, CA; 4 Positive Probability Limited, Isleham, UK.During the development of cancer, tumor cells alter glycosylation of proteins leading to changes in the growth, adhesion, signaling, and immune surveillance of the tumor. These glycosylation changes are known to correlate with increasing tumor burden and poor prognosis. Current immunochemical tests for cancer biomarkers, which include CA125, CA 15-3 or CA 19-9 are antibody-based assays for glycosylated proteins often associated with ovarian, breast cancer or other cancer types. These tests are not specific or sensitive enough for early detection of cancer and are not recommended by the American Society of Clinical Oncology for this purpose. As an adjunct to current immunochemical, proteomic or other methods for detection and diagnosis of cancer in patient serum, we have developed methods to chemically cleave oligosaccharides (glycans) from their protein cores that are present in serum samples. The resulting free glycan species are then analyzed by matrix-assisted laser desorption ionization (MALDI) or electrospray ionization (ESI) Fourier Transform Mass Spectrometry (FTMS). Further structural analysis of the glycans can be performed in the FTMS through the use of tandem mass spectrometry with infrared multi-photon dissociation (IRMPD) to sequence and confirm their oligosaccharide identification and core structure. Based on this analysis, glycan profiles are being created that will represent the glycosylation changes associated with the cancer disease state of the patient, which are sufficiently different from cancer free or normal patient serum. These glycan profiles will contain distinct glycan biomarkers that we hope can be signatures of We are using these methods to determine if we can detect significant glycan differences in the serum of ovarian, breast or prostate cancer patients that are not found in non-cancer patients. We have already analyzed condition media from tumor cell lines and cancer patient serum samples and have identified a panel of potential glycan cancer biomarkers that appear to correlate with the presence of cancer. We are in the process of determining whether these serum glycan biomarkers correlate with disease state. We envision that this test can be used as a diagnostic aid or to monitor treatment or predict outcome. This glycan profile test must be sensitive, specific and reproducible in order to take this technology from the laboratory bench to the bedside of the cancer patient.
Many Exciplex Systems Exhibit Organic Long‐Persistent Luminescence (2020)

Abstract Organic long‐persistent luminescence (OLPL) is a long‐lasting luminescence from a photogenerated intermediated state, such as a charge separated state. Here, it is shown that many exciplex systems exhibit OLPL and that emission pathways of OLPL can be controlled by the relationship among local excited states and charge‐transfer excited states of materials.
Production and Characterization of Monoclonal Antibodies against the Antibiotic Tilmicosin (2005)

Monoclonal antibodies (Mabs) were developed that specifically bind tilmicosin. Keyhole limpet hemocyanin (KLH) and bovine serum albumin (BSA) conjugates were used for the immunogen and plate coating antigen, respectively. The conjugates were synthesized by different methods, resulting in different linkages. Six hybridoma cell lines were isolated that produced Mabs that competed with tilmicosin, and have IgG1 isotype. The Til-1 and Til-5 Mabs had IC50 values for tilmicosin of 9.6 and 6.4 ng/well (48 and 32 ng/mL), respectively, and limits of detection at IC20 of 1.84 and 0.89 ng/well (9.2 and 4.45 ng/mL), respectively. The Mabs demonstrated high cross-reactivity to the macrolides containing 3,5-dimethylpiperidine at C20 and the amino sugar at C5. No cross-reactivity was observed for tylosin and other macrolides that did not contain 3,5-dimethylpiperidine. A competitive enzyme-linked immunosorbent assay (ELISA) was developed for the antibiotic tilmicosin by use of the developed Mabs. These Mabs may be excellent candidates for the determination and immunolocalization of tilmicosin.
Systematic Error-Correcting Codes for Rank Modulation (2014)

The rank-modulation scheme has been recently proposed for efficiently storing data in nonvolatile memories. In this paper, we explore [n, k, d] systematic error-correcting codes for rank modulation. Such codes have length n, k information symbols, and minimum distance d. Systematic codes have the benefits of enabling efficient information retrieval in conjunction with memory-scrubbing schemes. We study systematic codes for rank modulation under Kendall's T-metric as well as under the ℓ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">∞</sub> -metric. In Kendall's T-metric, we present [k + 2, k, 3] systematic codes for correcting a single error, which have optimal rates, unless systematic perfect codes exist. We also study the design of multierror-correcting codes, and provide a construction of [k + t + 1, k, 2t + 1] systematic codes, for large-enough k. We use nonconstructive arguments to show that for rank modulation, systematic codes achieve the same capacity as general error-correcting codes. Finally, in the ℓ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">∞</sub> -metric, we construct two [n, k, d] systematic multierror-correcting codes, the first for the case of d = 0(1) and the second for d = Θ(n). In the latter case, the codes have the same asymptotic rate as the best codes currently known in this metric.
Isolation of Human Adipose-derived Stem Cells from Biopsies and Liposuction Specimens (2008)

Adipose tissue has proven to serve as an abundant, accessible, and rich source of adult stem cells with multipotent properties suitable for tissue engineering and regenerative medical applications. Here, we describe a detailed method for the isolation and expansion of adipose-derived stem cells (ASCs). We present a large scale procedure suitable for processing >100 mL volumes of lipoaspirate tissue specimens and a small scale procedure suitable for processing adipose tissue biopsy specimens of < 0.5 g. Although we have focused on the isolation of ASCs from human adipose tissue, the procedure can be applied to adipose tissues from other species with minimal modifications.
Synthesis and properties of alkylene‐linked aromatic polyimides (1978)

Abstract Alkylene‐linked aromatic polyimides were prepared from a family of new dianhydride monomers and aromatic diamines. The dianhydrides were synthesized by Friedel‐Crafts catalysis of the condensation of ditertiary alcohols with o ‐xylene, subsequent oxidation of the aryl methyl groups to carboxy, and finally, dehydration of the ortho ‐carboxy substituents to anhydride groups. Alkylene‐linked aromatic polyimides, with up to 8 methylene groups in the polymer chain, are stable to 400°C in air and can be extruded or compression‐molded at 300°C. In addition, these polymers are soluble in solvents within the solubility parameter range of 10.4 ± 1.2.