gebhart/patrepeval huggingface dataset:
Digital phase-locked loop for frequency distribution over packet networks (2011)

This paper describes a digital phase-locked loop (DPLL) for frequency synchronization over packet networks. This timestamp-based technique for frequency synchronization involves a transmitter clock sending periodically an explicit time indication or timestamp to the receiver so that it can synchronize its local clock to that of the transmitter. The digital oscillator used in the PLL is a divide-by-N counter type oscillator (DNCO). We explain how the DPLL can be designed using standard control theory concepts and show how the loop filter gains are readily obtained given known/specified loop components such as phase detector and DNCO and a set of DPLL performance specifications.
Steric effects in photochromic polysiloxanes with spirooxazine side groups (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSteric effects in photochromic polysiloxanes with spirooxazine side groupsAlexander Zelichenok, Frida Buchholtz, Shlomo Yitzchaik, Judith Ratner, Mark Safro, and Valeri KrongauzCite this: Macromolecules 1992, 25, 12, 3179–3183Publication Date (Print):June 1, 1992Publication History Published online1 May 2002Published inissue 1 June 1992https://pubs.acs.org/doi/10.1021/ma00038a025https://doi.org/10.1021/ma00038a025research-articleACS PublicationsRequest reuse permissionsArticle Views277Altmetric-Citations29LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Sulfur tolerant highly durable CO.sub.2 sorbents (2012)

A sorbent for the capture of carbon dioxide from a gas stream is provided, the sorbent containing calcium oxide (CaO) and at least one refractory dopant having a Tammann temperature greater than about 530.degree. C., wherein the refractory dopant enhances resistance to sintering, thereby conserving performance of the sorbent at temperatures of at least about 530.degree. C. Also provided are doped CaO sorbents for the capture of carbon dioxide in the presence of SO.sub.2.
AMERICAN RESEARCH IN INTELLIGENT VEHICLE-HIGHWAY SYSTEMS - AN OVERVIEW (1991)

American research in intelligent vehicle-highway systems (IVHS) is largely driven by the needs for IVHS to enhance mobility and safety of automobile travel. With a basic strength in modular technologies relevant to IVHS, the United States has put research emphasis on system integration, including the driver in the loop. Interdisciplinary research is being conducted, combining the purely technical with the human-social elements. Industry, government, and university are joining forces in a number of research consortia. International cooperation might begin in basic research.
The (un)expected benefits of coaxial antennas for MRI (2021)

Shielded-coaxial-cable loops, or high impedance coils (HICs), are receiving increased interest in the MRI community because of performance benefits such as better decoupling, lower peak SAR in transmit mode and a flexible coil design. In this work, we summarize our recent efforts in understanding and applying coaxial conductors for antenna design in MRI.
Zero-Voltage-Switching Half-Bridge DC–DC Converter With Modified PWM Control Method (2004)

Asymmetric control scheme is an approach to achieve zero-voltage switching (ZVS) for half-bridge isolated dc-dc converters. However, it is not suited for wide range of input voltage due to the uneven voltage and current components stresses. This paper presents a novel "duty-cycle-shifted pulse-width modulated" (DCS PWM) control scheme for half-bridge isolated dc-dc converters to achieve ZVS operation for one of the two switches without causing the asymmetric penalties in the asymmetric control and without adding additional components. Based on the DCS PWM control scheme, an active-clamp branch comprising an auxiliary switch and a diode is added across the isolation transformer primary winding in the half-bridge converter to achieve ZVS for the other main switch by utilizing energy stored in the transformer leakage inductance. Moreover, the auxiliary switch also operates at ZVS and zero-current switching (ZCS) conditions. Furthermore, during the off-time period, the ringing resulted from the oscillation between the transformer leakage inductance and the junction capacitance of two switches is eliminated owing to the active-clamp branch and DCS PWM control scheme. Hence, switching losses and leakage-inductance-related losses are significantly reduced, which provides the converter with the potential to operate at higher efficiencies and higher switching frequencies. The principle of operation and key features of the proposed DCS PWM control scheme and two ZVS half-bridge topologies are illustrated and experimentally verified.
Evaluation of a Smart Algorithm for Commercial Vehicle Driver Drowsiness Detection (2007)

Drowsiness is a safety hazard in commercial vehicle driving. The conditions to which truck drivers are exposed put them at higher risk as compared to passenger car drivers. Unobtrusive drowsiness detection methods can avoid catastrophic crashes by warning or assisting the drivers. This paper describes an experimental analysis of commercially licensed drivers who were subjected to drowsiness conditions in a truck driving simulator and evaluates the performance of a neural network based algorithm which monitors only the drivers' steering input. Correlations are found between the change in steering and the state of drowsiness. The results show steering signals differences can be used effectively for detection.
Solid-immersion imaging interferometric nanoscopy to the limits of available frequency space (2012)

Imaging interferometric nanoscopy (IIN) is a synthetic aperture approach offering the potential of optical resolution to the linear-system limit of optics (~λ/4n). The immersion advantages of IIN can be realized if the object is in close proximity to a solid-immersion medium with illumination and collection through the substrate and coupling this radiation to air by a grating on the medium surface opposite the object. The spatial resolution as a function of the medium thickness and refractive index as well as the field-of-view of the objective optical system is derived and applied to simulations.
COTA (colon-ovarian tumor antigen): An Immunohistochemical Study (1986)

A goat anti-serum was prepared against mucinous ovarian cyst fluid and absorbed with normal colon and a variety of normal tissues until the only residual immunoreactivity was directed against colon cancer and ovarian tumor mucin. The set of antigenic determinants defined by this anti-serum has been called COTA, standing for colon-ovarian-tumor-antigen. This highly absorbed anti-serum (anti-COTA) was used for immunohistochemical staining of 42 different tissues in parallel with staining with a goat anti-CEA, which was also highly absorbed. The results suggest that COTA is a highly sensitive and specific antigen for colon carcinoma and may have potential for the early detection of malignant changes predictive of cancer of the colon.
Low-complexity inverse integer transform in H.264/AVC (2010)

This work develops an efficiently low-complexity method to compute a 2-dimensional inverse integer transform in H.264/AVC. First, the end-of-block points in 4 × 4 and 8 × 8 blocks are computed and then used to select one of 7 and 15 operation modes for each block, respectively. Second, the computation order of row-after-column and column-after-row used for 1-dimensional inverse integer transforms is adequately chosen to reduce computational complexity. Finally, simplified 1-dimensional inverse integer transforms are employed to accomplish a 2-dimensional inverse integer transform. The simulation results demonstrate that the proposed method can effectively minimize computational complexity of 2-dimensional inverse integer transforms in video streams of H.264/AVC. Particularly, as the smaller is the end-of-block point, the lower is the computational complexity. Therefore, the proposed method can be widely used at various H.264/AVC decoders to reach low-complexity computation.
Multi-Sensor Fault Recovery in the Presence of Known and Unknown Fault Types (2009)

This paper proposes an efficient online, hybrid, Bayesian multi-sensor fusion algorithm for target tracking in the presence of modelled and unmodelled faults. The algorithm comprises two stages. The first stage attempts to remove modelled faults from each individual sensor estimate. The second stage de-emphasises estimates which have been subject to unanticipated faults and are still faulty despite undergoing the Stage 1 fault recovery process. The algorithm is a computationally efficient and decentralisable hybrid of two standard approaches to fault detection, namely model-based fault detection and majority voting. The algorithm is tested on two distinct simulated scenarios (1) when the target process model does not match reality and (2) in the presence of simultaneous modelled and unanticipated faults. ©2009 ISIF.
Morphology control in electrochemically grown conducting polymer films. Part 2.—Effects of cathodic bias on anodically grown films studied by spectroscopic ellipsometry and quartz-crystal microbalance (1993)

We describe studies of effects of electrochemical growth conditions on the morphology of films of polyaniline (PANI). From single-wavelength ellipsometric measurements during film growth at constant anodic current, we have concluded that the temporary application of a cathodic bias during such an anodic growth process brings about an effect of (electrochemical) film annealing. This conclusion is further supported by a spectroscopic ellipsometric study. The spectroscopic study shows that, following temporary application of a cathodic bias during the galvanostatic growth of PANI films, the absorption peak in the near-infrared, associated with polarons in doped PANI, is shifted to lower photon energies. Such a shift is expected as a result of higher long-range order. The film annealing effect induced by temporary application of a cathodic bias is corraborated by further experimental evidence from quartz-crystal microbalance and electrode potential measurements. This beneficial morphological effect explains, at least in part, why potential multicycling has become a preferred mode of electrochemical growth of conducting polymer films. We suggest a possible interpretation for such annealing effects in an anodically grown conducting-polymer film brought about by interruption of the anodic growth current and temporary application of a cathodic bias. Elucidation of this phenomenon could be also valuable in the clarification of effects of undoping–redoping cycles applied to conducting-polymer membranes to achieve optimized gas-separation characteristics.
In vivo fiber tractography of the right and left ventricles using diffusion tensor MRI of the entire human heart (2014)

Background Diffusion Tensor MRI (DTI) tractography of the human heart in vivo has previously been performed with either large slice gaps or limited coverage [1,2]. The aim of this study was to investigate the feasibility of performing DTI of the entire human heart in vivo without slice gaps. This, we hypothesized, would enhance the characterization of fiber architecture in the left ventricle (LV), allow myofiber organization in the right ventricle (RV) to be characterized in vivo, and further elucidate microstructural differences in the heart between systole and diastole. Methods
Successive Correlated Defaults in a Structural Model (2004)

We propose a multi-firm first-passage credit model in which investors have incomplete information. In this model, investors cannot observe a firm's value process and its default barrier process. The model accounts for the short term risk inherent in default events, the market-wide impact of defaults on security prices due to counterparty relations between firms, and the cyclical default correlation effects observed in credit markets. We explicitly calculate the pricing trend and the arrival intensity of the first, second, etc. default. These results furnish (1) tractable reduced form formulas for arrival probabilities of successive correlated defaults and prices of multi-name credit derivatives that depend on the first, second etc. default, and (2) an algorithm for the simulation of successive unpredictable default times.
siRNA rescues nonhuman primates from advanced Marburg and Ravn virus disease (2017)

Ebolaviruses and marburgviruses belong to the family Filoviridae and cause high lethality in infected patients. There are currently no licensed filovirus vaccines or antiviral therapies. The development of broad-spectrum therapies against members of the Marburgvirus genus, including Marburg virus (MARV) and Ravn virus (RAVV), is difficult because of substantial sequence variability. RNAi therapeutics offer a potential solution, as identification of conserved target nucleotide sequences may confer activity across marburgvirus variants. Here, we assessed the therapeutic efficacy of lipid nanoparticle (LNP) delivery of a single nucleoprotein–targeting (NP-targeting) siRNA in nonhuman primates at advanced stages of MARV or RAVV disease to mimic cases in which patients begin treatment for fulminant disease. Sixteen rhesus monkeys were lethally infected with MARV or RAVV and treated with NP siRNA-LNP, with MARV-infected animals beginning treatment four or five days after infection and RAVV-infected animals starting treatment three or six days after infection. While all untreated animals succumbed to disease, NP siRNA-LNP treatment conferred 100% survival of RAVV-infected macaques, even when treatment began just 1 day prior to the death of the control animals. In MARV-infected animals, day-4 treatment initiation resulted in 100% survival, and day-5 treatment resulted in 50% survival. These results identify a single siRNA therapeutic that provides broad-spectrum protection against both MARV and RAVV.
Broadband multicoil imaging using multiple demodulation hardware: A feasibility study (2005)

Multiple receiver-coil data collection is an effective approach to reduce scan time. There are many parallel imaging techniques that reduce scan time using multiple receiver coils. One of these methods, partially parallel imaging with localized sensitivities (PILS), utilizes the localized sensitivity of each coil. The advantages of PILS over other parallel imaging methods include the simplicity of the algorithm, good signal-to-noise ratio (SNR) properties, and the fact that there is no additional complexity involved in applying the algorithm to arbitrary k-space trajectories. This PILS method can be further improved to provide truly parallel broadband imaging with the use of multiple-demodulation hardware. By customizing the demodulation based on each coil's location, the k-space sampling rate can be chosen based on each coil's localized sensitivity region along the readout direction. A simulated demodulation of data from 2D Fourier transform (FT) and spiral trajectories is shown to demonstrate the method's feasibility.
Non-homogeneous ICD optimization for targeted reconstruction of volumetric CT (2008)

Medical imaging typically requires the reconstruction of a limited region of interest (ROI) to obtain a high resolution image of the anatomy of interest. Although targeted reconstruction is straightforward for analytical reconstruction methods, it is more complicated for statistical iterative techniques, which must reconstruct all objects in the field of view (FOV) to account for all sources of attenuation along the ray paths from x-ray source to detector. A brute force approach would require the reconstruction of the full field of view in highresolution, but with prohibitive computational cost. In this paper, we propose a multi-resolution approach to accelerate targeted iterative reconstruction using the non-homogeneous ICD (NH-ICD) algorithm. NH-ICD aims at speeding up convergence of the coordinate descent algorithm by selecting preferentially those voxels most in need of updating. To further optimize ROI reconstruction, we use a multi-resolution approach which combines three separate improvements. First, we introduce the modified weighted NH-ICD algorithm, which weights the pixel selection criteria according to the position of the voxel relative to the ROI to speed up convergence within the ROI. Second, we propose a simple correction to the error sinogram to correct for inconsistencies between resolutions when the forward model is not scale invariant. Finally, we leverage the flexibility of the ICD algorithm to add selected edge pixels outside the ROI to the ROI reconstruction in order to minimize transition artifacts at the ROI boundary. Experiments on clinical data illustrate how each component of the method improves convergence speed and image quality.
268: Biochemical and Pharmacological Evidence for a Third Isozyme of Steroid 5A-Reductase in Prostate Cancer (2007)

You have accessJournal of UrologyModerated Poster 10, Sunday, May 20, 2007, 10:00 am - 12:00 pm1 Apr 2007268: Biochemical and Pharmacological Evidence for a Third Isozyme of Steroid 5A-Reductase in Prostate Cancer Mark Titus, Yun Li, Elzbieta Kawinski, Olga Kozyreva, and James L. Mohler Mark TitusMark Titus More articles by this author , Yun LiYun Li More articles by this author , Elzbieta KawinskiElzbieta Kawinski More articles by this author , Olga KozyrevaOlga Kozyreva More articles by this author , and James L. MohlerJames L. Mohler More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)30533-0AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "268: Biochemical and Pharmacological Evidence for a Third Isozyme of Steroid 5A-Reductase in Prostate Cancer." The Journal of Urology, 177(4S), p. 90 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 177Issue 4SApril 2007Page: 90 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information Mark Titus More articles by this author Yun Li More articles by this author Elzbieta Kawinski More articles by this author Olga Kozyreva More articles by this author James L. Mohler More articles by this author Expand All Advertisement PDF DownloadLoading ...
Arming the oncolytic virus enadenotucirev (EnAd) to generate enhanced locally-acting immunotherapies for cancer (2015)

Meeting abstracts EnAd is a potent, chimeric Ad11p/Ad3 adenovirus with selective oncolytic activity against a range of epithelial cancer cells. Ongoing clinical studies have shown that i.v. dosed EnAd infects and selectively replicates in tumor cells, producing detectable levels of viral protein,
Optimization of Q-switched lasers (1991)

The authors extend the standard rate equation analysis to obtain expressions for the maximum peak power, maximum pulse energy, and minimum pulsewidth of a single Q-switched output pulse; the maximum power efficiency of a repetitively Q-switched laser; and the corresponding cavity output couplings. Results are obtained analytically and numerically, and a comparison of the two sets of results is made. As a first step in this process the authors derive general expressions for the peak power, pulsewidth, pulse energy, and power efficiency. The authors next differentiate these expressions in order to find the maxima or minima that optimize the parameter of interest. Differentiation is done with respect to the cavity output coupling.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Structural Characterizations of Long Single-Walled Carbon Nanotube Strands (2002)

Centimeter long single-walled carbon nanotube strands synthesized using chemical vapor deposition method were characterized using microscopy, micro-Raman spectroscopy, and small-angle X-ray diffraction techniques. The strands are large collections of well-aligned nanotube bundles, which consist of well-arranged single-walled nanotubes in a two-dimensional triangular lattice. The diameter of the single-walled nanotubes varies from 1.1 to 1.7 nm, with domination of the 1.1 nm tubes and the corresponding lattice constant of 1.42 nm.
Statistical Validation of Risk Alleles in Genetic Addiction Risk Severity (GARS) Test: Early Identification of Risk for Alcohol Use Disorder (AUD) in 74,566 Case–Control Subjects (2022)

Since 1990, when our laboratory published the association of the DRD2 Taq A1 allele and severe alcoholism in <i>JAMA</i>, there has been an explosion of genetic candidate association studies, including GWAS. To develop an accurate test to help identify those at risk for at least Alcohol Use Disorder (AUD), Blum's group developed the Genetic Addiction Risk Severity (GARS) test, consisting of ten genes and eleven associated risk alleles. In order to statistically validate the selection of these risk alleles measured by GARS, we applied strict analysis to studies that investigated the association of each polymorphism with AUD or AUD-related conditions published from 1990 until 2021. This analysis calculated the Hardy-Weinberg Equilibrium of each polymorphism in cases and controls. If available, the Pearson's <i>χ</i><sup>2</sup> test or Fisher's exact test was applied to comparisons of the gender, genotype, and allele distribution. The statistical analyses found the OR, 95% CI for OR, and a post-risk for 8% estimation of the population's alcoholism prevalence revealed a significant detection. The OR results showed significance for DRD2, DRD3, DRD4, DAT1, COMT, OPRM1, and 5HTT at 5%. While most of the research related to GARS is derived from our laboratory, we are encouraging more independent research to confirm our findings.
A Concept for a Mobile Remote Manipulator System (1985)

A conceptual design for a Mobile Remote Manipulator System (MRMS) is presented. This concept does not require continuous rails for mobility (only guide pins at truss hardpoints) and is very compact, being only one bay square. The MRMS proposed is highly maneuverable and is able to move in any direction along the orthogonal guide pin array under complete control at all times. The proposed concept would greatly enhance the safety and operational capabilities of astronauts performing EVA functions such as structural assembly, payload transport and attachment, space station maintenance, repair or modification, and future spacecraft construction or servicing. The MRMS drive system conceptual design presented is a reasonably simple mechanical device which can be designed to exhibit high reliability. Developmentally, all components of the proposed MRMS either exist or are considered to be completely state of the art designs requiring minimal development, features which should enhance reliability and minimize costs.