gebhart/patrepeval huggingface dataset:
Smooth YBa2Cu3O7−<i>x</i> thin films prepared by pulsed laser deposition in O2/Ar atmosphere (1994)

We report on pulsed laser deposition of YBa2Cu3O7−x in a diluted O2/Ar gas resulting in thin epitaxial films which are almost outgrowth-free. Films were deposited on SrTiO3 or MgO substrates around 800 °C at a total chamber pressure of 1.0 mbar, varying the argon partial pressure from 0 to 0.6 mbar. The density of boulders and outgrowths usual for laser deposited films varies strongly with Ar pressure: the outgrowth density is reduced from 1.4×107 to 4.5×105 cm−2 with increasing Ar partial pressure, maintaining a critical temperature Tc,zero≊90 K and a transport critical current density Jc(77 K)≥106 A/cm2 by extended oxygenation time during cool down.
Nonrandom chromosomal changes in transitional cell carcinoma of the bladder. (1984)

Nine cases of transitional cell carcinoma (eight from the urinary bladder and one from the ureter; six noninvasive and three invasive) were subjected to detailed cytogenetic analysis with a G-banding method. The synchronization of primary cultures with methotrexate for high-resolution banding was performed in five cases. In the remaining four cases, the chromosomes were obtained from short-term cultures after prolonged (16 hr) exposure to Colcemid. Two cases were near-tetraploid, one was hypotriploid, and six were near-diploid (three hyperdiploid and three hypodiploid). All but one case showed various structural abnormalities in the karyotype. The chromosomal changes ranged from the presence of only two abnormal chromosomes (markers) to complex karyotypes with as many as 15 markers. In most tumors, the origin of the marker chromosomes could be readily deciphered. The nonrandom chromosomal aberrations included: (a) an isochrosome of the short arm of chromosome 5 (three cases); (b) monosomy of chromosome 9 found in four cases (this was the sole abnormality in one case); (c) involvement of chromosome 8 as an isochromosome of the long arm (two cases) or loss of the short arm due to deletion (one case) or translocation (one case); and (d) interstitial deletion of chromosome 13 (three cases). Our results indicate that the formation of i(5p) and monosomy 9 may be the primary karyotypic changes in two subgroups of transitional cell carcinoma. Involvement of chromosomes 8 and 13, on the other hand, seems to be a result of secondary karyotypic evolution. Two invasive tumors showed the presence of secondary clones, with additional structural chromosome aberrations superimposed on those already existing in the main cell population. In both cases, the additional aberrations involved the short arm of chromosome 11, resulting in loss of genetic material from the short arm. The short arm of chromosome 11, is the putative site of an oncogene which has been isolated from human bladder carcinoma cell lines. Deletion of the 11p was also seen in one case of noninvasive transitional cell carcinoma localized in the ureter; the material from 11p was probably translocated to chromosome 13. These findings suggest that the loss of genetic material from the short arm of chromosome 11 is a secondary event in the karyotypic evolution of transitional cell carcinoma, probably related to the invasive behavior of the tumor.
Diffraction coupled phase-locked semiconductor laser array (1983)

A new monolithic, diffraction coupled phase-locked semiconductor laser array has been fabricated. Stable narrow far-field patterns (∼3°) and peak power levels of 1 W have been obtained for 100-μm-wide devices with threshold currents as low as 250 mA. Such devices may be useful in applications where high power levels and stable radiation patterns are needed.
Infections Acquired during Cardiopulmonary Resuscitation: Estimating the Risk and Defining Strategies for Prevention (1998)

The benefit of initiating lifesaving resuscitation in a patient in cardiopulmonary arrest greatly outweighs the risk for secondary infection in the rescuer or the patient. Nevertheless, use of simple infection-control measures during CPR and CPR training can reduce a very low level of risk even further.
Effect of methotrexate sorbed on modified 2-hydroxyethylmethacrylate carriers in mice of C3H strain with a solid Gardner lymphosarcoma. (1977)

A aminohexylderivative of 2-hydroxyethylmethacrylpolymer has been prepared in the form of a microporous sponge, and Methotrexate (MTX) has been bound to this carrier by chemical sorption. Implantation of the carrier with sorbed MTX resulted in a decrease of tumor weight, while an implantation of the carrier alone or an i.p. injection of an identical dose of MTX had no effect on tumor growth. Tumor regression was found to be greater than after a repeated injection of MTX in a fourfold dose directly into the tumor.
On the Measurement of Market Power in the Banking Industry (2008)

Abstract: This paper compares the estimates of the two most widely used non‐structural models for market power measurement in banking, namely the conduct parameter method and the revenue test, as applied to three panels of Greek, Latvian and Spanish banks over the period 1993–2004. We also propose a dynamic reformulation of these models within a panel data context, in order to address possible statistical problems associated with the dynamic nature of bank‐level data. The results suggest that both static methods provide lower estimates of market power relative to their dynamic counterparts. Therefore, the inclusion of some dynamics in the models, even though it increased estimation complexity, helped to reveal some collusive behavior of banks.
Gender Socialization: Differences between Male and Female Youth in India and Associations with Mental Health (2014)

This paper describes patterns of gender socialization among youth in India and evaluates how these patterns are associated with their mental health. Data come from the Youth in India: Situation and Needs Study (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mi>N</mml:mi><mml:mo>=</mml:mo><mml:mtext>44,769</mml:mtext></mml:math>), a subnationally representative survey conducted during 2006–2008. Descriptive results underscored the gendered nature of socialization experiences, showing that male and female youth inhabit different social worlds. Female youth expressed more gender-egalitarian attitudes than male youth but reported greater restrictions to their independence than male youth. Male youth recognized more gender-discriminatory practices within their households than did the female youth. Poisson models revealed that female youth experienced more mental health problems when their households engaged in practices that favoured males over females, even as these same practices were associated with fewer mental health problems among male youth. Family violence and restrictions to independence were associated with mental health problems for both male and female youth. When males and females engaged in behaviours contravening sex-specific gender norms, there were corresponding increases in mental health problems for both sexes. Together, these findings suggest that gender inequality permeates family life in India, with corresponding consequences for the mental well-being of male and female youth.
The optimization of high performance liquid chromatographic method for analysis of trace microcystins in natural water bodies (2005)

The ratio of methanol., water and trifluoroacetic acid ( TFA) was regulated to change the polarity and the pH of the rinse solution and the eluent, so as to improve the high performance liquid chromatography HPLC) detection method for trace microcystines (MCs) in natural water bodies. The results showed that 40 % similar to 45 % methanol-water solution containing 0. 1 % TFA could get good effects on the rinse of impurity, and 70% methanol-water solution containing 0. 1% TFA could elute all the MCs in solid phase extraction ( SPE) cartridge ( C-18), In this way. it is suggested that, in analysis of environmental samples with high concentration of impurity, impurity should be washed with 40% similar to 45% methanol-water solution containing 0. 1% TFA, and MCs should be eluted with 70% similar to 100% methanol-water solution containing 0. 1% TFA.
Experimental Comparison Between Trigate p-TFET and p-FinFET Analog Performance as a Function of Temperature (2013)

This paper presents, for the first time, the experimental comparison between the p-type trigate FinFET and trigate p-TFET analog performances for devices fabricated on the same wafer. A careful analysis of the electrical characteristics is performed to choose the best bias conditions for the analog comparison between these devices. A higher intrinsic voltage gain is obtained for p-TFET devices because of their better output conductance, which is more than four orders of magnitude better than the one obtained for p-FinFET transistors at the same bias conditions from room temperature up to 150 <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex Notation="TeX">$^{\circ}{\rm C}$</tex></formula> .
Artificial cognition for social human–robot interaction: An implementation (2016)

Human–Robot Interaction challenges Artificial Intelligence in many regards: dynamic, partially unknown environments that were not originally designed for robots; a broad variety of situations with rich semantics to understand and interpret; physical interactions with humans that requires fine, low-latency yet socially acceptable control strategies; natural and multi-modal communication which mandates common-sense knowledge and the representation of possibly divergent mental models. This article is an attempt to characterise these challenges and to exhibit a set of key decisional issues that need to be addressed for a cognitive robot to successfully share space and tasks with a human. We identify first the needed individual and collaborative cognitive skills: geometric reasoning and situation assessment based on perspective-taking and affordance analysis; acquisition and representation of knowledge models for multiple agents (humans and robots, with their specificities); situated, natural and multi-modal dialogue; human-aware task planning; human–robot joint task achievement. The article discusses each of these abilities, presents working implementations, and shows how they combine in a coherent and original deliberative architecture for human–robot interaction. Supported by experimental results, we eventually show how explicit knowledge management, both symbolic and geometric, proves to be instrumental to richer and more natural human–robot interactions by pushing for pervasive, human-level semantics within the robot's deliberative system.
Colloidal polypyrrole (2023)

Processable electrically conductive latex polymer compositions including colloidal particles of an oxidized, polymerized aromatic heterocyclic monomer, a stabilizing effective amount of a vinyl pyridine-containing polymer and dopant anions and a method of preparing such polymer compositions are disclosed.
LvsA, a Protein Related to the Mouse Beige Protein, Is Required for Cytokinesis in<i>Dictyostelium</i> (1999)

We isolated a Dictyostelium cytokinesis mutant with a defect in a novel locus called large volume sphere A (lvsA). lvsA mutants exhibit an unusual phenotype when attempting to undergo cytokinesis in suspension culture. Early in cytokinesis, they initiate furrow formation with concomitant myosin II localization at the cleavage furrow. However, the furrow is later disrupted by a bulge that forms in the middle of the cell. This bulge is bounded by furrows on both sides, which are often enriched in myosin II. The bulge can increase and decrease in size multiple times as the cell attempts to divide. Interestingly, this phenotype is similar to the cytokinesis failure of Dictyostelium clathrin heavy-chain mutants. Furthermore, both cell lines cap ConA receptors but form only a C-shaped loose cap. Unlike clathrin mutants, lvsA mutants are not defective in endocytosis or development. The LvsA protein shares several domains in common with the molecules beige and Chediak-Higashi syndrome proteins that are important for lysosomal membrane traffic. Thus, on the basis of the sequence analysis of the LvsA protein and the phenotype of the lvsA mutants, we postulate that LvsA plays an important role in a membrane-processing pathway that is essential for cytokinesis.
In vivo measurement of nicotinic acetylcholine receptors with [<sup>18</sup>F]norchloro‐fluoro‐homoepibatidine (2007)

Functional changes of nicotinic acetylcholine receptors (nAChR) are important during age-related neuronal degeneration. Recent studies demonstrate the applicability of the nAChR ligand 2-[(18)F]F-A-85380 for neuroimaging of patients with dementias. However, its binding kinetics demands a 7-h acquisition time limiting its practicality for clinical PET studies. Thus, the authors developed [(18)F]norchloro-fluoro-homoepibatidine ([(18)F]NCFHEB) for nAChR imaging. The kinetics of the two enantiomers of [(18)F]NCFHEB were compared with 2-[(18)F]F-A85380 in porcine brain to evaluate their potential for human neuroimaging. Twenty-four juvenile female pigs were studied with PET using [(18)F]NCFHEB. Nine animals received an additional i.v. injection (1 mg/kg) of the nAChR agonist A81418 before radiotracer administration followed by infusion (2 mg/kg/7h) thereafter. Several compartment models were applied for quantification. (-)- and (+)-[(18)F]NCFHEB showed a twofold to threefold higher brain uptake than 2-[(18)F]F-A-85380. All three radiotracers displayed spatially heterogeneous binding kinetics in regions with high, moderate, or low specific binding. The equilibrium of specific binding of (-)-[(18)F]NCFHEB was reached earlier than that of (+)-[(18)F]NCFHEB or 2-[(18)F]F-A85380. Continuous administration of the nAChR agonist A81418 inhibited the specific binding of (-)- and (+)-[(18)F]NCFHEB but not of 2-[(18)F]F-A85380. The peripheral metabolism of (+)-[(18)F]NCFHEB proceeded somewhat slower than that of the other radiotracers. Both enantiomers of [(18)F]NCFHEB are appropriate radiotracers for neuroimaging of nAChR in pigs. Their binding profile in vivo appears to be more selective than that of 2-[(18)F]F-A85380. (-)-[(18)F]NCFHEB offers a faster equilibrium of specific binding than 2-[(18)F]F-A85380.
Latin Hypercube Sampling Jaya Algorithm based Strategy for T-way Test Suite Generation (2020)

T-way testing is a sampling strategy that generates a subset of test cases from a pool of possible tests. Many t-way testing strategies appear in the literature to-date ranging from general computational ones to meta-heuristic based. Owing to its performance, man the meta-heuristic based t-way strategies have gained significant attention recently (e.g. Particle Swarm Optimization, Genetic Algorithm, Ant Colony Algorithm, Harmony Search, Jaya Algorithm and Cuckoo Search). Jaya Algorithm (JA) is a new metaheuristic algorithm, has been used for solving different problems. However, losing the search's diversity is a common issue in the metaheuristic algorithm. In order to enhance JA's diversity, enhanced Jaya Algorithm strategy called Latin Hypercube Sampling Jaya Algorithm (LHS-JA) for Test Suite Generation is proposed. Latin Hypercube Sampling (LHS) is a sampling approach that can be used efficiently to improve search diversity. To evaluate the efficiency of LHS-JA, LHS-JA is compared against existing metaheuristic-based t-way strategies. Experimental results have shown promising results as LHS-JA can compete with existing t-way strategies.
Discovery of a Gut-Restricted JAK Inhibitor for the Treatment of Inflammatory Bowel Disease (2020)

To identify Janus kinase (JAK) inhibitors that selectively target gastrointestinal tissues with limited systemic exposures, a class of imidazopyrrolopyridines with a range of physical properties was prepared and evaluated. We identified compounds with low intrinsic permeability and determined a correlation between permeability and physicochemical properties, clogP and tPSA, for a subset of compounds. This low intrinsic permeability translated into compounds displaying high colonic exposure and low systemic exposure after oral dosing at 25 mg/kg in mouse. In a mouse PK/PD model, oral dosing of lead compound <b>2</b> demonstrated dose-dependent inhibition of pSTAT phosphorylation in colonic explants post-oral dose but low systemic exposure and no measurable systemic pharmacodynamic activity. We thus demonstrate the utility of JAK inhibitors with low intrinsic permeability as a feasible approach to develop gut-restricted, pharmacologically active molecules with a potential advantage over systemically available compounds that are limited by systemic on-target adverse events.
Soluble CD40 Ligand Plasma Levels in Lung Cancer (2004)

These findings indicate that elevated sCD40L levels can be preferentially found in patients with advanced squamous cancer and provide evidence that increased levels of this cytokine are associated to the occurrence of in vivo platelet activation.
Immunocytochemistry in the diagnosis of Kaposi's sarcoma and angiosarcoma. (1995)

Immunocytochemistry in the assessment of Kaposi's sarcoma and angiosarcoma is reviewed, with emphasis on the technical appraisal of the appropriate panel of markers. Problems incurred in the interpretation of the pathological spectrum of both tumours are discussed.
Backpack VLBI terminal with subscentimeter capability (1980)

Backpack portable equipment was developed to measure vector baseline from approximately 1 km to 100 km in length with subcentimeter to few centimeter accuracy. The equipment design features as well as the instrumentation specifications are discussed. It is shown that the unit has the following advantages: it is simple in concept; it is reliable in unattended operation; and it is inexpensive (less than $15,000 per unit).
A NOVEL POLARIZATION INDEPENDENT CHIPLESS RFID TAG USING MULTIPLE RESONATORS (2015)

A novel polarization independent RFID tag employing multiple resonators is proposed. The prototype of the tag is fabricated on a low-cost substrate of dielectric constant 4.4 and loss tangent 0.02. Designing a reader for chipless RFID is a hard task since both the polarization and operating frequency agility have to be implemented. The new tag design proposed in this paper is polarization independent, making the design of the reader easier. A prototype of a 3 bit data encoded tag is demonstrated using single structure which can be extended to any order by cascading. This new design is experimentally validated in the frequency domain using monostatic measurement with magnitude response to decode the information.
Phase-noise-canceling heterodyne receivers for coherent optical communication systems (1989)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text Y. H. CHENG, E. A. J. MARCATILI, and T. OKOSHI, "Phase-noise-canceling heterodyne receivers for coherent optical communication systems," in Optical Fiber Communication Conference, Vol. 5 of 1989 OSA Technical Digest Series (Optica Publishing Group, 1989), paper TUI7. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
ONNC: A Compilation Framework Connecting ONNX to Proprietary Deep Learning Accelerators (2019)

This paper presents ONNC (Open Neural Network Compiler), a retargetable compilation framework designed to connect ONNX (Open Neural Network Exchange) models to proprietary deep learning accelerators (DLAs). The intermediate representations (IRs) of ONNC have one-to-one mapping to ONNX IRs, thus making porting ONNC to proprietary DLAs much simpler than other compilation frameworks such as TVM and Glow especially for hardware with coarse-grained operators that are not part of the generic IRs in the LLVM backend. ONNC also has a flexible pass manager designed to support compiler optimizations at all levels. A docker image of ONNC bundled with a Vanilla backend is released with this paper to enable fast porting to new hardware targets. To illustrate how an ONNC-based toolkit guides our research and development in DLA design, we present a case study on compiler optimizations for activation memory consumption. The study shows that the Best-Fit algorithm with a proposed heuristic and a reordering scheme may act as a near-optimal strategy, getting the memory consumption close to the ideal lower bound in 11 of 12 models from the ONNX model zoo. To our best knowledge, ONNC is the first open source compilation framework that is specially designed to support the ONNX-based models for both commercial and research projects for deep learning applications.
Recent advancements in the production of rhamnolipid biosurfactants by<i>Pseudomonas aeruginosa</i> (2020)

Rhamnolipid (RL) biosurfactant which is produced by <i>Pseudomonas</i> species is one of the most effective surface-active agents investigated in the literature. Over the years, many efforts have been made and an array of techniques has been developed for the isolation of RL produced strains as well as RL homolog characterization. Reports show that RL productivity by the best-known producer, <i>Pseudomonas aeruginosa</i>, is very diverse, from less than 1 gr/l to more than 200 g L<sup>-1</sup>. There are some major parameters that can affect RL productivity. These are culture conditions, medium composition, the mode of operation (batch, fed-batch and continuous), bioengineering/gene manipulation and finally extraction methods. The present paper seeks to provide a comprehensive overview on the production of rhamnolipid biosurfactant by different species of <i>Pseudomonas</i> bacteria. In addition, we have extensively reviewed their potential for possible future applications.
The RASSF1A tumor suppressor (2007)

RASSF1A (Ras association domain family 1 isoform A) is a recently discovered tumor suppressor whose inactivation is implicated in the development of many human cancers. Although it can be inactivated by gene deletion or point mutations, the most common contributor to loss or reduction of RASSF1A function is transcriptional silencing of the gene by inappropriate promoter methylation. This epigenetic mechanism can inactivate numerous tumor suppressors and is now recognized as a major contributor to the development of cancer. RASSF1A lacks apparent enzymatic activity but contains a Ras association (RA) domain and is potentially an effector of the Ras oncoprotein. RASSF1A modulates multiple apoptotic and cell cycle checkpoint pathways. Current evidence supports the hypothesis that it serves as a scaffold for the assembly of multiple tumor suppressor complexes and may relay pro-apoptotic signaling by K-Ras.
Structure-Based Modeling of SARS-CoV-2 Peptide/HLA-A02 Antigens (2020)

SARS-CoV-2-specific CD4 and CD8 T cells have been shown to be present in individuals with acute, mild, and asymptomatic Coronavirus disease (COVID-19). Toward the development of diagnostic and therapeutic tools to fight COVID-19, it is important to predict and characterize T cell epitopes expressed by SARS-CoV-2. Here, we use RosettaMHC, a comparative modeling approach which leverages existing structures of peptide/MHC complexes available in the Protein Data Bank, to derive accurate 3D models for putative SARS-CoV-2 CD8 epitopes. We outline an application of our method to model 8-10 residue epitopic peptides predicted to bind to the common allele HLA-A<sup>*</sup>02:01, and we make our models publicly available through an online database (https://rosettamhc.chemistry.ucsc.edu). We further compare electrostatic surfaces with models of homologous peptide/HLA-A<sup>*</sup>02:01 complexes from human common cold coronavirus strains to identify epitopes which may be recognized by a shared pool of cross-reactive TCRs. As more detailed studies on antigen-specific T cell recognition become available, RosettaMHC models can be used to understand the link between peptide/HLA complex structure and surface chemistry with immunogenicity, in the context of SARS-CoV-2 infection.