gebhart/patrepeval huggingface dataset:
Decoder architecture for generalised concatenated codes (2015)

This paper proposes a pipelined decoder architecture for generalised concatenated (GC) codes. These codes are constructed from inner binary Bose–Chaudhuri–Hocquenghem (BCH) and outer Reed–Solomon codes. The decoding of the component codes is based on hard decision syndrome decoding algorithms. The concatenated code consists of several small BCH codes. This enables a hardware architecture where the decoding of the component codes is pipelined. A hardware implementation of a GC decoder is presented and the cell area, cycle counts as well as the timing constraints are investigated. The results are compared to a decoder for long BCH codes with similar error correction performance. In comparison, the pipelined GC decoder achieves a higher throughput and has lower area consumption.
Potential Application of Chitin Signaling in Engineering Broad-Spectrum Disease Resistance to Fungal and Bacterial Pathogens in Plants (2013)

Chitin, a polymer of N-acetylglucosamine, is an important structural component in the cell walls of fungal pathogens. Plant chitinases are capable of degrading this component to directly inhibit infection by fungal pathogens. Plants can further detect the chitin fragments released by chitinases to trigger additional defense responses. Recent studies have identified chitin receptors in different plant species and a number of downstream signaling components. The chitin-mediated signal transduction pathway appears to be a unique and promising target for engineering plants for broad-spectrum resistance to various fungal as well as bacterial pathogens.
Chalcogenide glass-based three-dimensional photonic crystals (2000)

AsSeTe chalcogenide glasses are materials that are photosensitive and have a large refractive index. These properties make these glasses particularly suitable for the fabrication of photonic crystals. We present a way to build three-dimensional photonic structures from chalcogenide glasses using vapor deposition and direct holographic writing. We show that this technique is intrinsically self-aligned, providing a simple way to build layer-by-layer photonic crystals and a four-layer structure demonstrating the principle of the technique.
New applications of copper vapor lasers in micromachining (1994)

We have developed a copper vapor laser based micromachinig system using advanced beam quality control and precision wavefront tilting technologies. Precision microdrilling has been demonstrated through percussion drilling and trepanning using this system. With a 30-W copper vapor from running at multi-kHz pulse repetition frequency, straight parallel holes with size varying from 500 microns to less than 25 microns and with aspect ratio up to 1:40 have been consistently drilled with good surface finish on a variety of metals. Micromilling and microdrilling on ceramics using a 250-W copper vapor laser have also been demonstrated with good result. Materialographic sections of machined parts show little (submicron scale) recast layer and heat affected zone.
Analysis of capacitance ratio of a rectangular X-cut length-extensional mode quartz crystal resonator by stresses (2006)

The electrical properties of an X-cut, length-extensional mode quartz crystal resonator of a cut angle theta around the X-axis were calculated by a variational method using stresses as trial functions. Analytical expressions of stresses were estimated by a linear regression on a cut angle best-fit to the results of finite-element method. The calculated dependence of the capacitance ratio on the cut angle was consistent with the measured results.
Simple Scheme for Polarization-Independent All-Optical Sampling (2004)

We propose and demonstrate a simple, single-path technique for polarization-independent all-optical sampling in fiber. The residual polarization dependence was only 0.3 dB and no polarization-dependent waveform distortion was observed.
Physical Basis for Separation of Rice Starch using Various Density Gradient Systems and its Effect on Starch Recovery, Purity, and Pasting Properties (2003)

Abstract A 32% waxy and non waxy rice flour slurry containing starch‐protein agglomerates was physically disrupted in presence of water by use of high pressure homogenizer called Microfluidizer®. Microfluidized rice flour slurry from passes 2 and 4 was collected followed by isolation of starch using three different density gradient solutions/systems (CeCl, NaCl/sucrose and ZnSO 4 ·7H 2 O). Complete deagglomeration was obtained after passing the rice flour slurry four times through the Microfluidizer®. The recovery of isolated starch varied from 76.28% to 91.20% for different density gradient systems. The degree of deagglomeration did not seem to affect recovery but affected the purity of the isolated starches. All starches produced from pass 4 rice slurry resulted in starches with residual protein below 0.5%. Higher density of the gradient solution resulted in higher recovery and purity of starch. The isolation method had a significant effect on the pasting properties of the isolated starch. Residual protein in isolated starch had a negative correlation with peak viscosity and setback of pass 2 waxy and nonwaxy starches. The salts were retained in purified starch despite rigorous washing (at least 75 times greater than the control) and could affect starch properties.
Inhibition of Diacylglycerol–Sensitive TRPC Channels by Synthetic and Natural Steroids (2012)

TRPC channels are a family of nonselective cation channels that regulate ion homeostasis and intracellular Ca(2+) signaling in numerous cell types. Important physiological functions such as vasoregulation, neuronal growth, and pheromone recognition have been assigned to this class of ion channels. Despite their physiological relevance, few selective pharmacological tools are available to study TRPC channel function. We, therefore, screened a selection of pharmacologically active compounds for TRPC modulating activity. We found that the synthetic gestagen norgestimate inhibited diacylglycerol-sensitive TRPC3 and TRPC6 with IC(50)s of 3-5 µM, while half-maximal inhibition of TRPC5 required significantly higher compound concentrations (>10 µM). Norgestimate blocked TRPC-mediated vasopressin-induced cation currents in A7r5 smooth muscle cells and caused vasorelaxation of isolated rat aorta, indicating that norgestimate could be an interesting tool for the investigation of TRP channel function in native cells and tissues. The steroid hormone progesterone, which is structurally related to norgestimate, also inhibited TRPC channel activity with IC(50)s ranging from 6 to 18 µM but showed little subtype selectivity. Thus, TRPC channel inhibition by high gestational levels of progesterone may contribute to the physiological decrease of uterine contractility and immunosuppression during pregnancy.
DNA‐Directed Assembly of Antibody–Fluorophore Conjugates for Quantitative Multiparametric Flow Cytometry (2013)

Multiparametric flow cytometry offers a powerful approach to single-cell analysis with broad applications in research and diagnostics. Despite advances in instrumentation, progress in methodology has lagged. Currently there is no simple and efficient method for antibody labeling or quantifying the number of antibodies bound per cell. Herein, we describe a DNA-directed assembly approach to fluorescent labeling that overcomes these barriers. Oligonucleotide-tagged antibodies and microparticles can be annealed to complementary oligonucleotides bearing fluorophores to create assay-specific labeling probes and controls, respectively. The ratio of the fluorescence intensity of labeled cells to the control particles allows direct conversion of qualitative data to quantitative units of antibody binding per cell. Importantly, a single antibody can be labeled with any fluorophore by using a simple mix-and-match labeling strategy. Thus, any antibody can provide a quantitative probe in any fluorescent channel, thus overcoming major barriers to the use of flow cytometry as a technique for systems biology and clinical diagnostics.
First Demonstration of a Bending-Mode Elastocaloric Cooling ‘Loop’ (2018)

This paper describes the first demonstration of solid-state elastocaloric cooling using Nitinol (NiTi) wire in a continuous `flow loop' configuration. Elastocaloric material performance was determined by infrared thermography uniaxial- or bending-mode mechanical stress. The effects of strain rate (from 0.001 to 0.025 s <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-1</sup> ) and strain mode on the temperature evolution and coefficient of performance (COP) were determined. Benchmark uniaxial results show a strain-induced adiabatic temperature reduction of 16°C, calculated material endothermic latent heat of 7.52 J/g, and a maximum material COP of 3.5. Bending-mode experiments, performed using the same alloy, show a temperature reduction of 9°C with a 6× reduction in required actuation force and equivalent material COP values to uniaxial testing. Based on bending-mode strain, a first-of-a-kind elastocaloric cooling `flow loop' using NiTi wire tracking around a designed radius of curvature was demonstrated. Continuous cooling of 1.85°C with a maximum cooling power of 49 mW was obtained. Future studies, which aim to improve the material latent heat, mechanical efficiency, and hot-side cooling efficiency, are expected to provide significant improvements in cooling power and temperature drop for equivalent operating conditions.
Development of Dental Scaler Tip Mold with Powder Injection Molding Process (2007)

With the capability of net shaping for complex 3D geometry, powder injection molding (PIM) is widely used for automotive parts, electronics and medical industry. In this study, an ultrasonic dental scaler tip produced by machining process was redesigned for the PIM process. An injection mold was designed and machined to produce the dental scaler tip by the PIM process. The mold design was aided by CAE analysis. A PIM feedstock was made of SUS316L powder and a wax based binder. The filling balance in the mold was checked by a short shot test with LDPE and the PIM feedstock. Production capability of the PIM process for the dental scaler tip was examined with the mold. Although there were minor problems such as a discoloration around the gate and a flashing at the air vent, the PIM process turned out to be an excellent substitute for machining process to manufacture the ultrasonic dental scaler tip.
FBG-based widely tunable multichannel chromatic dispersion compensation for DWDM communications systems (2002)

We describe a nonlinearly chirped fiber Bragg grating (FBG) based multichannel device that can perform tunable chromatic dispersion compensation. Complex or phase only sampling allows a single grating to operate on multiple DWDM channels. Various key performance parameters are discussed.
Induction of Protective Immunity against<i>Chlamydia trachomatis</i>Genital Infection by a Vaccine Based on Major Outer Membrane Protein–Lipophilic Immune Response-Stimulating Complexes (2000)

The significance of delivery systems in modern vaccine design strategies is underscored by the fact that a promising vaccine formulation may fail in vivo due to an inappropriate delivery method. We evaluated the immunogenicity and efficacy of a candidate vaccine comprising the major outer membrane protein (MOMP) of Chlamydia trachomatis delivered with the lipophilic immune response-stimulating complexes (ISCOMs) as a vehicle with adjuvant properties, in a murine model of chlamydial genital infection. Immunocompetent BALB/c mice were immunized intranasally (IN) or intramuscularly (IM) with MOMP, MOMP-ISCOMs, and live or heat-inactivated C. trachomatis serovar D. The level of local genital mucosal Th1 response was measured by assaying for antigen-specific Th1 cell induction and recruitment into the genital mucosa at different times after immunization. Immunization with MOMP-ISCOMs by the IM route induced the greatest and fastest local genital mucosal Th1 response, first detectable 2 weeks after exposure. Among the other routes and regimens tested, only IN immunization with MOMP-ISCOMs induced detectable and statistically significant levels of local genital mucosal Th1 response during the 8-week test period (P < 0.001). In addition, when T cells from immunized mice were adoptively transferred into syngeneic naive animals and challenged intravaginally with Chlamydia, recipients of IM immunization of MOMP-ISCOMs cleared their infection within 1 week and were resistant to reinfection. Animals that received IN immunization of MOMP-ISCOMs were partially protected, shedding fewer chlamydiae than did control mice. Altogether, the results suggested that IM delivery of MOMP-ISCOMs may be a suitable vaccine regimen potentially capable of inducing protective mucosal immunity against C. trachomatis infection.
Ag K-Edge EXAFS Analysis of DNA-Templated Fluorescent Silver Nanoclusters: Insight into the Structural Origins of Emission Tuning by DNA Sequence Variations (2011)

DNA-templated silver nanoclusters are promising biological fluorescence probes due to their useful fluorescence properties, including tunability of emission wavelength through DNA template sequence variations. Ag K-edge EXAFS analysis of DNA-templated silver nanoclusters has been used to obtain insight into silver nanocluster bonding, size, and structural correlations to fluorescence. The results indicate the presence of small silver nanoclusters (<30 silver atoms) containing Ag-Ag bonds and Ag-N/O ligations to DNA. The DNA sequence used leads to differences in silver-DNA ligation as well as silver nanocluster size. The results support a model in which cooperative effects of both Ag-DNA ligation and variations in cluster size lead to the tuning of the fluorescence emission of DNA-templated silver nanoclusters.
Investigations of Antisense Oligonucleotides Targeted Against <i>bcl-2</i> RNAs (1993)

Expression of the bcl-2 gene becomes deregulated in many non-Hodgkin lymphomas as the result of t(14;18) chromosomal translocations. Because bcl-2 regulates the survival of cells, and because its over-expression is associated with cellular resistance to killing by chemotherapeutic drugs and gamma-irradiation, this gene and its mRNA and protein products represent ideal targets for designing novel therapeutic strategies for the treatment of cancer. Here we describe the effects of an 18-mer phosphodiester oligonucleotide that is complementary to the first 6 codons of the bcl-2 mRNA's open reading frame. When tested for inhibition of in vitro protein synthesis using RNAse-H-supplemented reticulocyte lysates and RNA prepared by in vitro transcription of a human bcl-2 cDNA, the bcl-2 antisense (AS) oligomer completely abolished Bcl-2 protein production at 10 microM, but had no effect on the in vitro translation of a chicken bcl-2 RNA that contained three mismatches relative to the oligomer binding site on the human bcl-2 RNA. A control 18-mer having the same base composition as the AS oligomer but with scrambled order (SC) was not inhibitory. Addition of AS and SC oligomers to cultures of a NIH-3T3 fibroblast cell line that had been stably infected with a recombinant retrovirus containing the same human bcl-2 cDNA used for in vitro transcription/translation experiments revealed concentration-dependent reductions in the relative levels of the 26-kD human Bcl-2 protein (as determined by immunoblotting) by the AS but not by the SC oligomer. Similar results were obtained when AS and SC oligomers were applied to a t(14;18)-containing lymphoma cell line SU-DHL-4 that was cultured in low-serum media. When used at 200 microM, the bcl-2 AS oligomer produced 84-95% reductions in Bcl-2 protein levels in SU-DHL-4 cells but had relatively little effect on the levels of other mitochondrial control proteins, suggesting that the inhibitory effects were specific. Treatment of SU-DHL-4 cells with AS oligomer lead to essentially complete loss of bcl-2 mRNA from cells within 1 day of addition to cultures, but presumably because of the long half-life of the Bcl-2 protein (approximately 14 h), commensurate reductions in Bcl-2 protein levels did not occur until 3 days.(ABSTRACT TRUNCATED AT 400 WORDS)
Audiovisual quality integration: Comparison of human-human and human-machine interaction scenarios of different interactivity (2010)

The quality of audio-visual services is largely influenced by the qualities of the auditory and the visual signals. Perception of both signals is integrated and a single audio-visual rating is formed. The integration function depends, however, on the type of application. In this paper, we compare different integration functions which have been determined from empirical data collected in human-human and human-machine scenarios with different degrees of interactivity. The results show that the impact of each modality depends on both, the type of scenario and its degree of interactivity.
Increasing the lock-in probability of blind symbol time offset estimators in OFDM systems (2015)

For orthogonal frequency division multiplexing (OFDM) receivers, the mutual orthogonality of the subcarriers is preserved only if the estimated symbol timing error lies in the lock-in region. Conventionally, a bias is added to the coarse symbol time offset (STO) estimate to move the symbol timing error into the lock-in region, thus increasing the lock-in probability. Upon review of the literature, no analysis has been provided on determining which bias values can improve the lock-in probability. This paper is the first to investigate adding a bias to blind coarse STO estimators, and analyze its performance in terms of the lock-in probability. It will be shown that the optimal value of the bias term is dependent on the channel, which is not ideal for blind estimators. Hence, an upper bound on the optimal value is derived that is valid for all channels, and then the bound is made tighter for realistic wireless communication channels. It is shown that these bounds are dependent solely on the length of the cyclic prefix, thus the coarse STO estimators remain blind.
Continuous epitopes of the human immunodeficiency virus type 1 (HIV-1) transmembrane glycoprotein and reactivity of human sera to synthetic peptides representing various HIV-1 isolates (1991)

Immunoreactive regions of human immunodeficiency virus type 1 (HIV-1) gp41 were mapped by reacting HIV-1 antibody-positive human sera with overlapping synthetic peptides which covered the transmembrane protein. Three immunoreactive domains were identified, and five different and partially overlapping epitopes recognized by HIV-1-positive human sera were found within one immunodominant region. The effect on antibody recognition after single amino acid substitutions within one defined epitope was also studied. The reactivity of various HIV-1-positive sera to synthetic peptides with amino acid substitutions representing known isolates suggests an important substitution in the major epitope of African HIV-1 strains.
Fluorinated Ethylene Carbonate as Electrolyte Additive for Rechargeable Na Batteries (2011)

Fluoroethylene carbonate is an efficient electrolyte additive to improve the reversibility of electrochemical sodium insertion for hard-carbon and NaNi(1/2)Mn(1/2)O(2) electrodes in aprotic Na cells. The additive is also capable of the electrochemical deposition/dissolution of metallic Na with higher reversibility because of improved passivation and suppression of side reactions between Na metal and propylene carbonate solution containing Na salts.
Optimized Modulation Strategy of NH3L-DAB Converter to Minimize RMS Current for Wide Voltage Range Applications (2022)

Dual active bridge (DAB) converter is one of the most popular bidirectional isolated dc/dc converters. Comparing with the two-level DAB converter, the multilevel DAB topologies take advantages of providing more control degrees of freedom to enhance the control flexibility. Therefore, these topologies are promising alternatives for wide voltage range applications. This article proposed an optimizing modulation strategy for neutral-point-clamped hybrid three-level dual active bridge (NH3L-DAB) converter to minimize the rms value of inductor current and the conduction losses. First, the basic operating principle of NH3L-DAB is analyzed comprehensively in the article. Afterward, the concept of global optimal condition is employed to derive the optimal modulation, and the corresponding analytical expressions of the control coordinates for rms current minimization are derived. By applying the optimal modulation strategy, NH3L-DAB facilitates to break the performance barriers of the prior-of-art of two-level DAB converter when the voltage transmission ratio has large variation. Finally, a bidirectional prototype with 200–450 V input and 20–28.8 V output is built to demonstrate the superior performance of the proposed optimal modulation strategy, and the detailed explanation of the experimental results is given as well.
Development of Aluminium Foam Processes and Products (2006)

Aluminum foams offer an attractive combination of attributes as engineering materials, such as low density, high rigidity, high energy absorption, and fire resistance. To date, however, metallic foams have achieved only a fraction of the market acceptance enjoyed by polymeric foams, owing largely to size limitations, poor uniformity and, above all, high unit costs. Methods utilizing casting (non-powder) metallurgy, while seemingly offering the potential of economies of scale, often suffer quality issues such as large cell sizes, poor uniformity and insufficient structural integrity. Many of these problems are associated with the rheology of the molten metal itself. While prior efforts to modify melt rheology through extrinsic additions of ceramic particles have been shown to be effective, the costly materials and processing paths used to create such suspensions have limited the economic attractiveness of such products. In this paper, aluminum foams produced through an alternative processing method will be described. The physical and mechanical properties in these fine (< 1 mm) celled aluminum foams will be related to their cellular structure and the properties of the aluminum alloy matrix from which they are produced.
<title>Adaptive color watermarking</title> (2002)

In digital watermarking, a major aim is to insert the maximum possible watermark signal while minimizing visibility. Many watermarking systems embed data in the luminance channel to ensure watermark survival through operations such as grayscale conversion. For these systems, one method of reducing visibility is for the luminance changes due to the watermark signal to be inserted into the colors least visible to the human visual system, while minimizing the changes in the image hue. In this paper, we develop a system that takes advantage of the low sensitivity of the human visual system to high frequency changes along the yellow-blue axis, to place most of the watermark in the yellow component of the image. We also describe how watermark detection can potentially be enhanced, by using a priori knowledge of this embedding system to intelligently examine possible watermarked images.
CdSiP 2 optical parametric generator (2011)

We report efficient generation of picosecond pulses in the near- and mid-infrared in the new nonlinear material CdSiP<sub>2</sub>pumped at 1.064 μm by an amplified mode-locked Nd:YVO<sub>4</sub> laser at 100 kHz repetition rate. Using single-pass optical parametric generation in 8-mm-long crystal cut for type I (e→00) noncritical phase-matching, an average idler power of 154 mW at 6.204 μm together with 1.16 W of signal at 1.282 μm has been obtained for 6.1 W of pump at photon conversion efficiencies of 15% and 23%, respectively. Signal pulse durations of 6.36 ps are measured for 9 ps pump pulses, with both signal and idler beams in near-Gaussian spatial profile.