gebhart/patrepeval huggingface dataset:
High-resolution transport-of-intensity quantitative phase microscopy with annular illumination (2017)

For quantitative phase imaging (QPI) based on transport-of-intensity equation (TIE), partially coherent illumination provides speckle-free imaging, compatibility with brightfield microscopy, and transverse resolution beyond coherent diffraction limit. Unfortunately, in a conventional microscope with circular illumination aperture, partial coherence tends to diminish the phase contrast, exacerbating the inherent noise-to-resolution tradeoff in TIE imaging, resulting in strong low-frequency artifacts and compromised imaging resolution. Here, we demonstrate how these issues can be effectively addressed by replacing the conventional circular illumination aperture with an annular one. The matched annular illumination not only strongly boosts the phase contrast for low spatial frequencies, but significantly improves the practical imaging resolution to near the incoherent diffraction limit. By incorporating high-numerical aperture (NA) illumination as well as high-NA objective, it is shown, for the first time, that TIE phase imaging can achieve a transverse resolution up to 208 nm, corresponding to an effective NA of 2.66. Time-lapse imaging of in vitro Hela cells revealing cellular morphology and subcellular dynamics during cells mitosis and apoptosis is exemplified. Given its capability for high-resolution QPI as well as the compatibility with widely available brightfield microscopy hardware, the proposed approach is expected to be adopted by the wider biology and medicine community.
A Molecular Signature in Superficial Bladder Carcinoma Predicts Clinical Outcome (2006)

No AccessJournal of UrologyAdult urology1 Apr 2006A Molecular Signature in Superficial Bladder Carcinoma Predicts Clinical Outcome L. Dyrskjot, K. Zieger, M. Kruhoffer, T. Thykjaer, J.L. Jensen, H. Primdahl, N. Aziz, N. Marcussen, K. Moller, and T.F. Orntoft L. DyrskjotL. Dyrskjot More articles by this author , K. ZiegerK. Zieger More articles by this author , M. KruhofferM. Kruhoffer More articles by this author , T. ThykjaerT. Thykjaer More articles by this author , J.L. JensenJ.L. Jensen More articles by this author , H. PrimdahlH. Primdahl More articles by this author , N. AzizN. Aziz More articles by this author , N. MarcussenN. Marcussen More articles by this author , K. MollerK. Moller More articles by this author , and T.F. OrntoftT.F. Orntoft More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)00865-7AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "A Molecular Signature in Superficial Bladder Carcinoma Predicts Clinical Outcome." The Journal of Urology, 175(4), p. 1274 References 1 : A second-look TUR in T1 transitional cell carcinoma: why?. Eur Urol2004; 45: 539. Google Scholar 2 : Clinical under staging of high risk nonmuscle invasive urothelial carcinoma treated with radical cystectomy. J Urol2001; 166: 490. Link, Google Scholar 3 : Impact of a second transurethral resection on the staging of T1 bladder cancer. Urology2002; 60: 822. Google Scholar Molecular Diagnostic Laboratory, Department of Clinical Biochemistry, Aarhus University Hospital, Aarhus, Denmark© 2006 by American Urological AssociationFiguresReferencesRelatedDetails Volume 175Issue 4April 2006Page: 1274 Advertisement Copyright & Permissions© 2006 by American Urological AssociationMetricsAuthor Information L. Dyrskjot More articles by this author K. Zieger More articles by this author M. Kruhoffer More articles by this author T. Thykjaer More articles by this author J.L. Jensen More articles by this author H. Primdahl More articles by this author N. Aziz More articles by this author N. Marcussen More articles by this author K. Moller More articles by this author T.F. Orntoft More articles by this author Expand All Advertisement PDF downloadLoading ...
Optimizing the precision of a multichannel three-polarizer spectroscopic ellipsometer (2013)

We developed a multichannel three-polarizer spectroscopic ellipsometer based on a data acquisition algorithm for achieving optimized precision. This algorithm measures unnormalized Fourier coefficients accurately and precisely. Offset angles for optical elements were obtained as wavelength-independent values using regression calibration. Derived subsets of data reduction functions were used to calculate sample parameters. Correlation coefficients of Fourier coefficients were used to calculate errors in the sample parameters. Mean standard deviations of the sample parameters for each data reduction method were compared to identify the best method. This approach could be used to identify suitable precision optimization methods for other rotating-element ellipsometers.
Band engineering, growth and characteristics of type-II InAs/GaSb superlattice-based detectors (2016)

We report on band engineering, growth and device performance of infrared photodetectors based on type II InAs/Ga(In)Sb strain layer superlattices (SLs) using the complementary barrier infrared detector (CBIRD) design. The unipolar barriers on either side of the absorber in the CBIRD design in combination with the type-II InAs/GaSb superlattice material system are expected to outperform traditional III-V LWIR imaging technologies and offer significant advantages over the conventional II-VI material based FPAs. The innovative design of CBIRDS, barrier and band offset engineering, low defect density material growth, and robust fabrication processes have resulted in the development of high performance long wave infrared (LWIR) focal plane arrays at JPL.
A 3.4W digital-in class-D audio amplifier (2011)

In this paper a class-D audio amplifier for mobile applications is presented realized in a 0.14μm CMOS technology tailored for mobile applications. The amplifier has a simple PDM-based digital interface that requires only two pins and enables assembly n 9-bump WL-CSP. A reconfigurable ate driver is used that reduces quiescent current consumption and radiated emission.
Low-noise microwave magnetrons by azimuthally varying axial magnetic field (2003)

A technique has been demonstrated to significantly reduce the noise in microwave oven magnetrons. The technique employs permanent magnets to generate an azimuthally varying axial magnetic field. Noise measurements are reported which show dramatic reductions in the noise of kW oven magnetrons operating near 2.45 GHz. The noise reduction near the carrier is some 30 dB. Microwave sidebands are reduced or eliminated. Noise reduction occurs at all anode currents, but is particularly significant at low current near the start-oscillation condition.
Modeling WDM Wavelength Switching Systems for Use in GMPLS and Automated Path Computation (2009)

Network control planes have made an implicit assumption that the switching devices in a network are symmetric. In wavelength-switched optical networks even the most basic switching element, the reconfigurable add–drop multiplexer, is highly asymmetric. This paper presents a model of optical switching subsystems for use in generalized multiprotocol label switching (GMPLS), route selection, and wavelength assignment. The model covers a large class of switching subsystems without internal wavelength converters. The model is applied to a number of common optical technologies, and a compact encoding for use in the optical control plane is furnished along with a method for deriving a simplified graph representation.
A concise radiosynthesis of the tau radiopharmaceutical, [<sup>18</sup>F]T807 (2013)

Fluorine-18 labeled 7-(6-fluoropyridin-3-yl)-5H-pyrido[4,3-b]indole ([(18) F]T807) is a potent and selective agent for imaging paired helical filaments of tau and is among the most promising PET radiopharmaceuticals for this target in early clinical trials. The present study reports a simplified one-step method for the synthesis of [(18) F]T807 that is broadly applicable for routine clinical production using a GE TRACERlab™ FXFN radiosynthesis module. Key facets of our optimized radiosynthesis include development and use of a more soluble protected precursor, tert-butyl 7-(6-nitropyridin-3-yl)-5H-pyrido[4,3-b]indole-5-carboxylate, as well as new HPLC separation conditions that enable a facile one-step synthesis. During the nucleophilic fluorinating reaction with potassium cryptand [(18) F]fluoride (K[(18) F]/K222 ) in DMSO at 130 °C over 10 min the precursor is concurrently deprotected. Formulated [(18) F]T807 was prepared in an uncorrected radiochemical yield of 14 ± 3%, with a specific activity of 216 ± 60 GBq/µmol (5837 ± 1621 mCi/µmol) at the end of synthesis (60 min; n = 3) and validated for human use. This methodology offers the advantage of faster synthesis in fewer steps, with simpler automation that we anticipate will facilitate widespread clinical use of [(18) F]T807.
Regulation and frequency response service capability of modern wind power plants (2010)

Wind speed variability generates the main challenges for grid integration of wind power. Worldwide, requirements governing generator connection to the transmission grid evolve as the modern energy industry continues to develop. With increased wind power penetration, wind power plants are required to provide grid support and control actions similar to conventional power plants. Dedicated control systems for wind power plants employing variable-speed wind turbines can provide advanced control features for the transmission network operator. The paper summarizes the control characteristics of a modern wind power plant. It identifies the capability of modern wind power plants to offer fast regulation and frequency response services. Advanced functionalities for regulation and response to grid disturbances are also addressed.
Newly developed high reliability palladium coated Cu wire for automotive application (2017)

In the past several years, Au bonding wire has been replaced with Cu wire in the field of LSI devices. In particular, Pd coated copper (PCC) and Au-Pd coated copper (APC) wire are the majority of the market share. Recently, a shift from Au wire to Cu wire is also expected for automotive devices. In order to apply Cu wire to automotive devices, high bond reliability is required under harsh environment. Especially, high temperature is a major concern to design and manage long term reliability. A new type of APC (new-APC) wire was developed to have better thermal reliability than bare Cu and conventional APC wire. New-APC wire has higher concentration of added element than APC wire. Furthermore, the new-APC wire has good bond properties similar to APC wire.
Functional analysis of MOR‐1 splice variants of the mouse mu opioid receptor gene <i>Oprm</i> (2003)

A series of mu opioid receptor gene Oprm splice variants have been reported that differ only at their C-terminus. These variants all contain exons 1, 2, and 3 of the gene, the exons responsible for coding all seven transmembrane domains. Whereas MOR-1 also has exon 4 that encodes for an additional 12 amino acids at the tip of the C-terminus, the other MOR-1 variants have unique amino acid sequences distinct from those in MOR-1 due to alternative splicing. All these variants are mu-selective in binding assays. The current study explored the ability of these variants to stimulate [35S]GTPgammaS binding to assess them functionally. Only mu opioids stimulated [35S]GTPgammaS binding. Among the mu opioids we noted marked differences in their maximal stimulation among the clones. This was most prominent with beta-endorphin, which stimulated [35S]GTPgammaS binding in the MOR-1E expressing cells to a greater degree than [D-Ala2,MePhe4,Gly(ol)5]enkephalin (DAMGO; 130%) and was far less effective than DAMGO in MOR-1C cells (44%). The rank order of maximal stimulation of the drugs varied among the clones as well. Dynorphin A, beta-endorphin and morphine were most effective in stimulating [35S]GTPgammaS binding in MOR-1E, while M6G and fentanyl were most effective in MOR-1 expressing cells. The potency (EC50) of some of the drugs also varied extensively among the clones, with a poor correlation between the potency of the drugs to stimulate [35S]GTPgammaS binding and their binding affinity. Together, these findings reveal marked functional differences among the variants that only can be explained by their structural differences at the tip of their C-terminus.
Identification of a second rat pancreatitis-associated protein. Messenger RNA cloning, gene structure, and expression during acute pancreatitis (1993)

The pancreatitis-associated protein (PAP) is a lectin-related secretory protein present in small amounts in the rat pancreas and overexpressed during the acute phase of pancreatitis. On the other hand, PAP is constitutively expressed in the intestinal tract but not in other tissues. We cloned from a pancreatic cDNA library two overlapping cDNAs encoding a protein structurally related to PAP. This second PAP, which was called PAP II, was the same size as the original PAP (PAP I) and showed 74.3% amino acid homology. Studies on gene expression demonstrated that PAP II mRNA concentration increased within 6 h following induction of pancreatitis, reached maximal levels (> 200 times control values) at 24-48 h, and decreased thereafter, similar to PAP I. However, PAP II mRNA could not be detected in the intestinal tract or in other tissues. We also isolated a PAP II genomic DNA fragment which was characterized over 2.7 kb of gene sequence and 1.9 kb of 5' flanking sequence. The 5' end of the coding sequence was determined by primer extension of the PAP II mRNA. The PAP II coding sequence spanned six exons separated by five introns. Several potential regulatory elements were identified in the promoter region, including two glucocorticoid-response elements and one IL-6-response element. Antibodies raised to a synthetic peptide of PAP II detected a single band in Western blot analysis of the pancreatic secretory proteins from rats with pancreatitis, with a M(r) compatible with the theoretical M(r) of PAP II.(ABSTRACT TRUNCATED AT 250 WORDS)
Novel zero-voltage-transition PWM converters (1994)

To date, soft-switching techniques applied to the PWM converters, with the exception of a few isolated cases, are subjected to either high switch voltage stresses or high switch current stresses, or both. A new class of zero-voltage-transition PWM converters is proposed, where both the transistor and the rectifier operate with zero-voltage switching and are subjected to minimum voltage and current stresses. Breadboarded converters are constructed to verify the novelty of the proposed new family of converters.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Critical area computation via Voronoi diagrams (1999)

In this paper, we present a new approach for computing the critical area for shorts in a circuit layout. The critical area calculation is the main computational problem in very large scale integration yield prediction. The method is based on the concept of Voronoi diagrams and computes the critical area for shorts (for all possible defect radii, assuming square defects) accurately in O(n log n) time, where n is the size of the input. The method is presented for rectilinear layouts and layouts containing edges of slope /spl plusmn/1. As a byproduct, we briefly sketch how to speed up the grid method of Wagner and Koren [1995].
A double-end-beam based infrared device fabricated using CMOS-MEMS process (2016)

Purpose Thermopile infrared (IR) detectors are one of the most important IR devices. Considering that the surface area of conventional four-end-beam (FEB)-based thermopile devices cannot be effectively used and the performance of this type of devices is relatively low, this paper aims to present a double-end-beam (DEB)-based thermopile device with high duty cycle and performance. The paper aims to discuss these issues. Design/methodology/approach Numerical analysis was conducted to show the advantages of the DEB-based thermopile devices. Findings Structural size of the DEB-based thermopiles may be further scaled down and maintain relatively higher responsivity and detectivity when compared with the FEB-based thermopiles. The authors characterized the thermoelectric properties of the device proposed in this paper, which achieves a responsivity of 1,151.14 V/W, a detectivity of 4.15 × 108 cm Hz1/2/W and a response time of 14.46 ms sensor based on DEB structure. Orginality/value The paper proposed a micro electro mechanical systems (MEMS) thermopile infrared sensor based on double-end-beam structure.
CDNet++: Improved Change Detection with Deep Neural Network Feature Correlation (2020)

In this paper, we present a deep convolutional neural network (CNN) architecture for segmenting semantic changes between two images. The main objective is to segment changes at the semantic level than detecting background changes, which are irrelevant to the application. The difficulties include seasonal changes, lighting differences, artifacts due to alignment and occlusion. The existing approaches fail to address all the problems together; thus, none of them achieve state-of-the-art performance in three publicly available change detection datasets: VL-CMU-CD [1], TSUNAMI [2] and GSV [2]. Our proposed approach is a simple yet effective method that can handle even adverse challenges. In our approach, we leverage the correlation between high-level abstract CNN features to segment the changes. Compared with several traditional and other deep learning-based change detection methods, our proposed method achieves state-of-the-art performance in all three datasets.
Large area flexible SERS active substrates using engineered nanostructures (2011)

Surface enhanced Raman scattering (SERS) is an analytical sensing method that provides label-free detection, molecularly specific information, and extremely high sensitivity. The Raman enhancement that makes this method attractive is mainly attributed to the local amplification of the incident electromagnetic field that occurs when a surface plasmon mode is excited at a metallic nanostructure. Here, we present a simple, cost effective method for creating flexible, large area SERS-active substrates using a new technique we call shadow mask assisted evaporation (SMAE). The advantage of large, flexible SERS substrates such as these is they have more area for multiplexing and can be incorporated into irregular surfaces such as clothing. We demonstrate the formation of four different types of nanostructure arrays (pillar, nib, ellipsoidal cylinder, and triangular tip) by controlling the evaporation angle, substrate rotation, and deposition rate of metals onto anodized alumina nanoporous membranes as large as 27 mm. In addition, we present experimental results showing how a hybrid structure comprising of gold nanospheres embedded in a silver nano-pillar structure can be used to obtain a 50× SERS enhancement over the raw nanoparticles themselves.
Efficient and secure software implementations of Fantomas. (2019)

In this paper, the efficient software implementation and side-channel resistance of the LS-Design construction are studied through a series of software implementations of the Fantomas block cipher, one of its most prominent instantiations. Target platforms include resource-constrained ARM devices like the Cortex-M3 and M4, and more powerful processors such as the ARM Cortex-A15 and modern Intel platforms. The implementations span a broad range of characteristics: 32-bit and 64-bit versions, unprotected and side-channel resistant, and vectorized code for NEON and SSE instruction sets. Our results improve the state of the art substantially, in terms of both efficiency and compactness, by making use of novel algorithmic techniques and features specific to the target platform. We finish by proposing and prototyping instruction set extensions to reduce by half the performance penalty of the introduced side-channel countermeasures.
Origins of Unusual Alcohol Selectivities over Mixed MgAl Oxide-Supported K/MoS<sub>2</sub> Catalysts for Higher Alcohol Synthesis from Syngas (2013)

A series of MoS2 catalysts supported on Mg/Al hydrotalcite-derived mixed-metal oxide (MMO) supports promoted with K2CO3 is used for alcohol synthesis via CO hydrogenation. Alcohol selectivities are found to vary greatly when the Mo is loaded on the support at 5 wt % compared with 15 wt % Mo samples, all with a Mo/K atomic ratio of 1:1. The most striking difference between the catalysts is the comparatively low methanol and high C3+ alcohol selectivities and productivities achieved with the 5% Mo catalyst. This catalyst also produces more ethane than the 15% Mo catalyst, which is shown to be associated with ethanol dehydration and hydrogenation over residual acid sites on this catalyst with lower K content. A series of catalysts with common composition (5% Mo and 3% K supported on MMO) prepared in different manners all yield similar catalytic selectivities, thus showing that selectivity is predominately controlled by the MMO-to-Mo ratio rather than the synthesis method. When the Mo loading is the same, catalytic higher alcohol productivity shows some correlation to the degree of stacking of the MoS2 layers, as assessed via X-ray diffraction and scanning transmission electron microscopy. Control reactions in which K loading is increased or the positioning of the MMO in the catalyst bed is changed via creation of multiple or mixed catalyst beds show that Mo/K/MMO domains play a significant role in alcohol-forming reactions. Higher alcohol-forming pathways are proposed to occur via CO insertion pathways or via coupling of adsorbed reaction intermediates at or near MoS2 domains. No evidence is observed for significant alcohol-coupling pathways by adsorption of alcohols over downstream, bare MMO supports. Nitrogen physisorption, XRD, Raman, UV–vis DRS, STEM, and XANES are used to characterize the catalysts, demonstrating that the degree of stacking of the MoS2 domains differs significantly between the low (5% Mo) and high (15% Mo) loading catalysts.
Model Predictive BESS Control for Demand Charge Management and PV-Utilization Improvement (2017)

Adoption of battery energy storage systems for behind-the-meters application offers valuable benefits for demand charge management as well as increasing PV-utilization. The key point is that while the benefit/cost ratio for a single application may not be favorable for economic benefits of storage systems, stacked services can provide multiple revenue streams for the same investment. Under this framework, we propose a model predictive controller to reduce demand charge cost and enhance PV-utilization level simultaneously. Different load patterns have been considered in this study and results are compared to the conventional rule-based controller. The results verified that the proposed controller provides satisfactory performance by improving the PV-utilization rate between 60% to 80% without significant changes in demand charge (DC) saving. Furthermore, our results suggest that batteries can be used for stacking multiple services to improve their benefits. Quantitative analysis for PV-utilization as a function of battery size and prediction time window has also been carried out.