gebhart/patrepeval huggingface dataset:
Monotone percolation and the topology control of wireless networks (2005)

This paper addresses the topology control problem for large wireless networks that are modelled by an infinite point process on a two-dimensional plane. Topology control is the process of determining the edges in the network by adjusting the transmission radii of the nodes. Topology control algorithms should be based on local decisions, be adaptive to changes, guarantee full connectivity and support efficient routing. We present a family of topology control algorithms that, respectively, achieve some or all of these requirements efficiently. The key idea in our algorithms is a concept that we call monotone percolation. In classical percolation theory, we are interested in the emergence of an infinitely large connected component. In contrast, in monotone percolation we are interested in the existence of a relatively short path that makes monotonic progress between any pair of source and destination nodes. Our key contribution is that we demonstrate how local decisions on the transmission radii can lead to monotone percolation and in turn to efficient topology control algorithms.
Toxic Releases from Power Plants (1999)

Beginning in 1998, electric power plants burning coal or oil must estimate and report their annual releases of toxic chemicals listed in the Toxics Release Inventory (TRI) published by the U.S. Environmental Protection Agency (EPA). This paper identifies the toxic chemicals of greatest significance for the electric utility sector and develops quantitative estimates of the toxic releases reportable to the TRI for a representative coal-fired power plant. Key factors affecting the magnitude and types of toxic releases for individual power plants also are discussed. A national projection suggests that the magnitude of electric utility industry releases will surpass those of the manufacturing industries which currently report to the TRI. Risk communication activities at the community level will be essential to interpret and provide context for the new TRI results.
Human activity recognition using smartphone sensors with two-stage continuous hidden Markov models (2014)

Recognizing human activities from temporal streams of sensory data observations is a very important task on a wide variety of applications in context recognition. Especially for time-series sensory data, a method that takes into account the inherent sequential characteristics of the data is needed. Moreover, activities are hierarchical in nature, in as much that complex activities can be decomposed to a number of simpler ones. In this paper, we propose a two-stage continuous hidden Markov model (CHMM) approach for the task of activity recognition using accelerometer and gyroscope sensory data gathered from a smartphone. The proposed method consists of first-level CHMMs for coarse classification, which separates stationary and moving activities, and second-level CHMMs for fine classification, which classifies the data into their corresponding activity classes. Random Forests (RF) variable importance measures are exploited to determine the optimal feature subsets for both coarse and fine classification. Experiments show that with the use of a significantly reduced number of features, the proposed method shows competitive performance in comparison to other classification algorithms, achieving an over-all accuracy of 91.76%.
Emerging oral targeted therapies in inflammatory bowel diseases: opportunities and challenges (2017)

To improve quality of life and prevent long-term risks in patients with inflammatory bowel diseases (IBDs: Crohn's disease, ulcerative colitis), it is essential to suppress inflammatory activity adequately. However, corticosteroids are only suitable for therapy of acute flares and the evidence for positive effects of immunosuppressive substances like azathioprine or 6-mercapropurine is mainly limited to maintenance of remission. In addition, only subgroups of patients benefit from biologicals targeting tumour necrosis factor α or α4β7 integrins. In summary, until now the disease activity is not sufficiently controlled in a relevant fraction of the patients with IBD. Thus, there is an urge for the development of new substances in the therapy of ulcerative colitis and Crohn's disease. Fortunately, new oral and parenteral substances are in the pipeline. This review will focus on oral substances, which have already passed phase II studies successfully at this stage. In this article, we summarize data regarding AJM300, phosphatidylcholine (LT-02), mongersen, ozanimod, filgotinib and tofacitinib. AJM300 and ozanimod were tested in patients with ulcerative colitis and target lymphocyte trafficking through inhibition of the α subunit of integrin, respectively binding to the sphingosine-1-phosphate receptor (subtypes 1 and 5) on lymphocytes. Mongersen was utilized in patients with Crohn's disease and accelerates the degradation of SMAD7 mRNA, which consequently strengthens the mainly anti-inflammatory signalling pathway of transforming growth factor β1. Various Janus kinase (JAK) inhibitors were developed, which inhibit the intracellular signalling pathway of cytokines. For example, the JAK1 blocker filgotinib was tested in Crohn's disease, whereas the JAK1/3 inhibitor tofacitinib was tested in clinical trials for both Crohn's disease and ulcerative colitis. A different therapeutic approach is the substitution of phosphatidylcholine (LT-02), which might recover the colonic mucus. Taken together, clinical trials with these new agents have opened avenues for further clinical studies and it can be expected that at least some of these agents will be finally approved for clinical therapy.
The Maine Lumbar Spine Study, Part III (1996)

At a 1-year evaluation of patient-reported outcomes, patients with severe lumbar spinal stenosis who were treated surgically had greater improvement than patients treated nonsurgically. Comparisons of outcomes by treatment received must be made cautiously because of differences in baseline characteristics. A determination of whether the outcomes observed persist requires long-term follow-up.
Analysis of the Pathogenic Human Mitochondrial Mutation ND1/3460, and Mutations of Strictly Conserved Residues in Its Vicinity, Using the Bacterium <i>Paracoccus d</i><i>enitrificans</i> (1998)

The human mitochondrial ND1/3460 mutation changes Ala52 to Thr in the ND1 subunit of Complex I, and causes Leber's hereditary optic neuropathy (LHON) [Huoponen et al. (1991) Am. J. Hum. Genet. 48, 1147]. We have used a bacterial counterpart of Complex I, NDH-1 from Paracoccus denitrificans, for studying the effect of mutations in the ND1 subunit on the enzymatic activity. The LHON mutation as well as several other mutations in strictly conserved amino acids in its vicinity were introduced into the NQO8 subunit of NDH-1, a bacterial homologue of ND1. The enzymatic activity of the mutants in the presence of hexammineruthenium (rotenone-insensitive) and ubiquinone-1 (rotenone-sensitive) were assayed. In addition, the kinetics of the interaction of selected mutant enzymes with ubiquinone-1, ubiquinone-2, and decylubiquinone was studied. The results suggest that the mutated residues play an important role in ubiquinone reduction by Complex I.
<i>Staphylococcus aureus</i>Exosecretions and Bovine Mastitis (2003)

The role of Staphylococcus aureus and coagulase-negative staphylococcal exosecretions in bovine udder infection was tested by monitoring the cows' response to in vivo inoculation of bacterial exosecretions into udder quarters. Twenty Israeli-Holstein dairy cows were included in the study; two or three of the udder quarters of each cow were intracisternally inoculated with 0.04-0.05 mg/quarter (total proteins) of the various sterile bacterial exosecretions in a sterile pyrogen-free saline. Each udder was inoculated with two or three different bacterial exosecretions or placebo (Columbia Broth). Cows were monitored for 96 h post-inoculation for rectal temperature, heart and respiratory rates, alimentary tract activity (rumen contraction), udder temperature, pain, oedema and udder size. Milk samples were examined bacteriologically and for somatic cell count, N-acetyl-D-glucosaminidase (NAGase) activity and somatic cell differentiation. No enterotoxins (beta-G) or toxic shock syndrome toxin-1 were detected in response to any of the bacteria tested. Control quarters or those inoculated with Columbia Broth, showed similar NAGase and somatic cell count values throughout the experiment. Twelve of the 18 strains tested, induced inflammation in the inoculated quarters while six did not. Of the 12 strains causing local inflammation, only six were found significantly different from the control and were considered as high response (group 1). The other six that caused a local inflammation did not differ significantly from the control, and were considered to be moderate response (group 2). The six S. aureus isolates that did not cause an inflammatory response were considered to have low response (group 3). In all quarters inoculated with S. aureus bacterial exosecretions belonging to groups 1 and 2, the polymorphonuclear cells and macrophages were proportionally increased while CD4+ and CD8+ T-lymphocyte populations decreased. One-dimensional NuPAGE (7%) Tris-acetate gel electrophoresisof the bacterial exosecretions revealed four different bands appearing between 36 and 31 kDa, marked from top to bottom as A, B, C and D. An association was found between the combinations of expressed bands and the cow responses: the majority of the cases could be linked to the expression of bands B and C.
[Plasma levels of complement fragments during hemodialysis in patients with chronic renal failure]. (1990)

The kinetics of hemodialysis-induced leukopenia and generation of complement fragments including C3a, C5a, C4d, iC3b and Bb were investigated in 14 patients during hemodialysis using cellulose acetate (CA), cuprophan (Cu) and ethylenevinyl alcohol (EVA) membranes. A marked leukopenia in the first 15 minutes was observed in CA and Cu. Plasma C3a levels were higher in CA than in Cu and EVA. Plasma C5a levels were higher in CA and Cu than in EVA. There was a negative correlation between the white blood cell counts and plasma C5a levels at 15 minutes (gamma = -0.85, p less than 0.001). Plasma C4d levels showed no increase in all membranes. Plasma iC3b levels were higher significantly in Cu than in CA and EVA. Plasma Bb levels in the first 15 minutes increased significantly in all membranes, and furthermore continued to increase till the end of hemodialysis in CA and Cu. This study revealed that all the membranes tested activated the complement via the alternative pathway to produce Bb, iC3b, C3a and C5a. C5a was thought to take an important role in transient leukopenia. Furthermore, Bb was accumulated during hemodialysis in CA and Cu, and its biological effects on patients undergoing hemodialysis should be studied.
A novel procedure for rapid isolation of plant growth promoting pseudomonads (1995)

A rapid and novel procedure for the isolation of plant growth promoting rhizobacteria (PGPR) is described. This method entails screening soil bacteria for the ability to utilize the compound 1-aminocyclopropane-1-carboxylate (ACC) as a sole N source, a trait that is a consequence of the presence of the activity of the enzyme ACC deaminase. This trait appears to be limited to soil bacteria that are also capable of stimulating plant growth. Seven different soil samples from two geographically disparate locations were found to contain pseudomonads that were able to to utilize ACC as a N source. Each of the seven strains was shown, by the ability of the bacterium to promote canola seedling root elongation under gnotobiotic conditions, to be a PGPR. The method described here may be used to replace the otherwise slow and tedious process of testing individual bacterial strains for their ability to promote plant growth, thereby significantly speeding up the process of finding new PGPR.Key words: plant growth promoting rhizobacteria, PGPR, 1-aminocyclopropane-1-carboxylate, ACC, ACC deaminase, bacterial fertilizer, soil bacteria.
Social Work Services in Schools. By Paula Allen-Meares, Robert O. Washington, and Betty L. Welsh. Englewood Cliffs, N.J.: Prenctice-Hall, 1986. 301 pp. $32.95 (1987)

Social Work Services in Schools. By Paula Allen-Meares, Robert O. Washington, and Betty L. Welsh. Englewood Cliffs, N.J.: Prenctice-Hall, 1986. 301 pp. $32.95 Get access Social Work Services in Schools. By Allen-Meares Paula, Washington Robert O., and Welsh Betty L.. Englewood Cliffs, N.J.: Prenctice-Hall, 1986. 301 pp. $32.95. Toy F. Watson Toy F. Watson Newport News Public SchoolsNewport News, Virginia Search for other works by this author on: Oxford Academic PubMed Google Scholar Social Work, Volume 32, Issue 1, January-February 1987, Page 88, https://doi.org/10.1093/sw/32.1.88-a Published: 01 January 1987
Learning to Disambiguate by Asking Discriminative Questions (2017)

The ability to ask questions is a powerful tool to gather information in order to learn about the world and resolve ambiguities. In this paper, we explore a novel problem of generating discriminative questions to help disambiguate visual instances. Our work can be seen as a complement and new extension to the rich research studies on image captioning and question answering. We introduce the first large-scale dataset with over 10,000 carefully annotated images-question tuples to facilitate benchmarking. In particular, each tuple consists of a pair of images and 4.6 discriminative questions (as positive samples) and 5.9 non-discriminative questions (as negative samples) on average. In addition, we present an effective method for visual discriminative question generation. The method can be trained in a weakly supervised manner without discriminative images-question tuples but just existing visual question answering datasets. Promising results are shown against representative baselines through quantitative evaluations and user studies.
Case 19-2011 (2011)

A 4-year-old Haitian boy was admitted to a hospital because of vomiting and diarrhea. On examination, he was hypovolemic and lethargic. Episodes of diarrhea became too numerous to count. Rehydration was initiated, and a diagnostic test result was received.
Quantum information processing with trapped ions (2003)

Experiments directed towards the development of a quantum computer based on trapped atomic ions are described briefly. We discuss the implementation of single-qubit operations and gates between qubits. A geometric phase gate between two ion qubits is described. Limitations of the trapped-ion method such as those caused by Stark shifts and spontaneous emission are addressed. Finally, we describe a strategy to realize a large-scale device.
Synthesis and micellization of new biodegradable phosphorylcholine‐capped polyurethane (2011)

Abstract To obtain controllable and biocompatible drug carriers, a series of amphiphilic biodegradable multiblock polyurethanes end‐capped by phosphorylcholine were designed and synthesized using L ‐lysine ethyl ester diisocyanate (LDI), poly(lactic acid)‐poly(ethylene glycol)‐poly(lactic acid) (PLA‐PEG‐PLA), 1,4‐butanediol (BDO), and 4‐hydroxy butyl phosphorylcholine (BPC) was used as end‐capper to improve their biocompatibility and provide them with tailored micellization characteristics. The resulting polyurethanes were fully characterized with proton nuclear magnetic resonance spectroscopy ( 1 H NMR), Fourier transform infrared spectroscopy (FT‐IR), gel permeation chromatograph (GPC), and differential scanning calorimetry (DSC). More importantly, these phosphorylcholine‐capped polyurethanes can self assemble into micelles that are smaller than 100 nm in diameter. Their particle sizes, size distributions, and zeta potentials can also be tailored by varying the phosphorylcholine content. The incorporation of phosphorylcholine into these polyurethanes has significantly affected their degree of microphase separation, bulk and micelle degradation rates. This work provides a new and facile approach to prepare amphiphilic block copolymer micelles with controllable performances, which could be useful for drug delivery and bioimaging applications. © 2011 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2011
Neutral Carrier-Type Ion Sensors Based on Sol−Gel-Derived Membranes Incorporating a Bis(crown ether) Derivative by Covalent Bonding (1998)

Sol-gel-derived membranes incorporating crown ether neutral carriers by covalent bonding have been designed for durable, nontoxic neutral carrier-type ion sensors by sol-gel processing using tetraethoxysilane, diethoxydimethylsilane, and their corresponding alkoxysilylated neutral carriers. A tetraphenylborate anion was also bound chemically to the neutral carrier-type sol-gel-derived membranes for suppressing anion interference and membrane impedance. Ion-sensitive field effect transistors (ISFETs) based on the sol-gel-derived membranes modified chemically by crown ether derivatives, such as 16-crown-5 and bis(12-crown-4) derivatives, showed high performance, high sensitivity in wide cation activity ranges, short response time, and high electrode durability. Specifically, high ion selectivities of practical use in biological systems were attained in the sodium ISFETs based on the chemically modified bis(12-crown-4), which has been successfully applied to sodium assay in blood sera.
A shallow junction submicrometer PMOS process without high temperature anneals (1988)

A PMOS process resulting in very shallow, low-leakage source-drain junctions without high-temperature annealing following doping is discussed. The doping is performed using gas immersion laser doping which relies on a melt/regrowth process, initiated by a pulsed excimer laser (XeCl, lambda =308 nm), to drive in the dopant species. The properties of the resulting source/drain layers are discussed. A significant feature of this process is that unwanted diffusions are eliminated because no high-temperature anneals are used after the doping step. Submicrometer PMOS devices fabricated using this process exhibit excellent short-channel behavior with some process conditions resulting in very little or no threshold-voltage shift down to submicrometer gate lengths.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Amorphous silicon carbide rear-side passivation and reflector layer stacks for multi-junction space solar cells based on germanium substrates (2017)

New developments for space solar cells mainly address efficiency improvements and weight reduction. In this paper we developed amorphous SiC based layer stacks for passivation and enhanced reflection on thin and lowly doped (2×10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">16</sup> - 1×10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">17</sup> at/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> ) Ge wafers. Passivated Ge samples with minority carrier lifetimes of more than 300 μs and surface recombination velocities of just 17 cm/s are presented. Thermal annealing at 400 °C and additional “mirror” layer deposition do not harm the minority carrier lifetimes or lead to an even slight increase. Electron irradiation with fluences of 1×10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">15</sup> e/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> and more lead to strong material degradation and lifetimes of just 5 μs.
The Degradation of Thermal Insulating Mineral Fibers (1984)

An experimental study has been carried out to investigate the effect of the water medium on the material behavior of the inorganic mineral fibers. This was conducted by exposing the mineral fibers to simulated environmental con ditions, in which an excessive water medium and a heating treatment at temperature up to 100°C were maintained for a relatively short period of about 3-4 months. Results of the study showed that these inorganic mineral fibers exhibit a physical change transforming the long and thread-like filaments into small segments and granules as a result of the simultaneous exposure to the heat-humidity treatment. Microscopic examinations showed that the fibers displayed a growth of foreign substance and formation of a reticular network structure on the surface of the individual fibers. The cause of this material degradation process has been interpreted to be related to a chemical leaching process.
The use of human fibrin glue in the surgical operations. (2003)

Human Fibrin Glue (HFG) is made of two components contained in separate vials: a freeze dried concentrate of clotting proteins, mainly fibrinogen, Factor XIII and fibronectin (the sealant) and freeze dried thrombin (the catalyst). The first component is reconstituted with an aprotinin solution that inhibits tissue fibrinolysis. The second component (thrombin), available in 500 I.U. concentration, is dissolved with calcium chloride. It is so a set of substances involved in the hemostatic process and in the wound healing, conferring to the product the following important properties: hemostatic and sealing action, through the strengthening of the last step of the physiological coagulation; biostimulation, which favors the formation of new tissue matrix. The indications for the use of human fibrin sealant are numerous and present in all the surgical branches. A randomized controlled trial of 50 patients undergoing hernia repair according to Lichtenstein's technique under local anesthesia was performed. Patients had concurrent coagulopathies as a consequence of liver disease or long-term treatment with anticoagulants for ischemic heart disease or cardiac rhythm disturbances. Coagulopathies were defined according to the following criteria: prothrombin time < 10.5 seconds, activated partial thromboplastin time < 21 seconds, and fibrinogen < 230 mg/dL. Patients were randomized in a 1:1 ratio with (group A) or without (control group B) use of human fibrin glue: Postoperative hemorrhagic complications were significantly reduced in group A (4%) compared with group B (24%). This study showed that human fibrin glue is effective in preventing local hemorrhagic complications after inguinal hernia repair in patients with concurrent coagulation disorders.
A new parallel method for molecular dynamics simulation of macromolecular systems (1996)

Short-range molecular dynamics simulations of molecular systems are commonly parallelized by replicated-data methods, in which each processor stores a copy of all atom positions. This enables computation of bonded 2-, 3-, and 4-body forces within the molecular topology to be partitioned among processors straightforwardly. A drawback to such methods is that the interprocessor communication scales as N (the number of atoms) independent of P (the number of processors). Thus, their parallel efficiency falls off rapidly when large numbers of processors are used. In this article a new parallel method for simulating macromolecular or small-molecule systems is presented, called force-decomposition. Its memory and communication costs scale as N/√P, allowing larger problems to be run faster on greater numbers of processors. Like replicated-data techniques, and in contrast to spatial-decomposition approaches, the new method can be simply load balanced and performs well even for irregular simulation geometries. The implementation of the algorithm in a prototypical macromolecular simulation code ParBond is also discussed. On a 1024-processor Intel Paragon, ParBond runs a standard benchmark simulation of solvated myoglobin with a parallel efficiency of 61% and at 40 times the speed of a vectorized version of CHARMM running on a single Cray Y-MP processor. © 1996 by John Wiley & Sons, Inc.