gebhart/patrepeval huggingface dataset:
Message from the Editor (1993)

Other| January 01 1993 Message from the Editor Marian Green Marian Green Search for other works by this author on: This Site PubMed Google Scholar Journal of Musicology (1993) 11 (1): 3–5. https://doi.org/10.2307/764146 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation Marian Green; Message from the Editor. Journal of Musicology 1 January 1993; 11 (1): 3–5. doi: https://doi.org/10.2307/764146 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu nav search search input Search input auto suggest search filter All ContentJournal of Musicology Search This content is only available via PDF. Copyright 1993 Regents of the University of California Article PDF first page preview Close Modal You do not currently have access to this content.
Mitotic partitioning and selective reorganization of tissue-specific transcription factors in progeny cells (2003)

Postmitotic gene expression requires restoration of nuclear organization and assembly of regulatory complexes. The hematopoietic and osteogenic Runx (Cbfa/AML) transcription factors are punctately organized in the interphase nucleus and provide a model for understanding the subnuclear organization of tissue-specific regulatory proteins after mitosis. Here we have used quantitative in situ immunofluorescence microscopy and quantitative image analysis to show that Runx factors undergo progressive changes in cellular localization during mitosis while retaining a punctate distribution. In comparison, the acetyl transferase p300 and acetylated histone H4 remain localized with DNA throughout mitosis while the RNA processing factor SC35 is excluded from mitotic chromatin. Subnuclear organization of Runx foci is completely restored in telophase, and Runx proteins are equally partitioned into progeny nuclei. In contrast, subnuclear organization of SC35 is restored subsequent to telophase. Our results show a sequential reorganization of Runx and its coregulatory proteins that precedes restoration of RNA processing speckles. Thus, mitotic partitioning and spatiotemporal reorganization of regulatory proteins together render progeny cells equivalently competent to support phenotypic gene expression.
Limonium carvalhoi (Plumbaginaceae), a new endemic species from the Balearic Islands (1998)

Limonium carvalhoi Rosselló & L. Sáez is described from a single salt marsh locality in southwest Majorca. Morphologically, L. carvalhoi is close to L. inexpectans, L. migjornense and L. magallufianum, all Balearic endemics. The new species has an apomictic breeding system and shows a single pollen/stigma combination (B/papillate type). Chromosome number ranges from 2n = 24 to 2n = 26. Based on the occurrence of a long metacentric chromosome in all cells examined, it is suggested that the original chromosome complement is 2n = 26, the other chromosome numbers being derived by descending aneuploidy.
An Efficient Modular Exponentiation Algorithm against Simple Power Analysis Attacks (2007)

Very few solutions are known to protect the modular exponentiation for single-chip devices against simple power analysis (SPA) attacks. In this paper, we present a model approach to address the power analysis problem. Using the model approach, we propose a modular exponentiation algorithm, which is secure under the SPA model. Compared with the known solutions, the proposed algorithm is more suitable for real-life applications .
RNA Editing in the Central Cavity as a Mechanism to Regulate Surface Expression of the Voltage-gated Potassium Channel Kv1.1 (2014)

Voltage-gated potassium (Kv) 1.1 channels undergo a specific enzymatic RNA deamination, generating a channel with a single amino acid exchange located in the inner pore cavity (Kv1.1(I400V)). We studied I400V-edited Kv1.1 channels in more detail and found that Kv1.1(I400V) gave rise to much smaller whole-cell currents than Kv1.1. To elucidate the mechanism behind this current reduction, we conducted electrophysiological recordings on single-channel level and did not find any differences. Next we examined channel surface expression in Xenopus oocytes and HeLa cells using a chemiluminescence assay and found the edited channels to be less readily expressed at the surface membrane. This reduction in surface expression was verified by fluorescence imaging experiments. Western blot analysis for comparison of protein abundances and glycosylation patterns did not show any difference between Kv1.1 and Kv1.1(I400V), further indicating that changed trafficking of Kv1.1(I400V) is causing the current reduction. Block of endocytosis by dynasore or AP180C did not abolish the differences in current amplitudes between Kv1.1 and Kv1.1(I400V), suggesting that backward trafficking is not affected. Therefore, our data suggest that I400V RNA editing of Kv1.1 leads to a reduced current size by a decreased forward trafficking of the channel to the surface membrane. This effect is specific for Kv1.1 because coexpression of Kv1.4 channel subunits with Kv1.1(I400V) abolishes these trafficking effects. Taken together, we identified RNA editing as a novel mechanism to regulate homomeric Kv1.1 channel trafficking. Fine-tuning of Kv1.1 surface expression by RNA editing might contribute to the complexity of neuronal Kv channel regulation.
Neurofeedback training for symptom reduction in children with dyslexia : multiple case study (2016)

Dyslexia is one of the most common neurobiological disorders, affecting about 20% of children in Norway. According to phonological theory of dyslexia, the disorder is caused by a deficit in the representation, storage and recall of speech sounds. Different brain areas have been linked to the phonological deficit by means of different brain imaging techniques, among other qEEG. Some interesting studies conducted by Breteler and colleagues (2010) and Nazari and colleagues (2012) have tried to improve reading ability among dyslexics by means of neurofeedback training. Their results have been essential to the construction and the design of the present study. The aim of this study was to investigate neurofeedback training to improve reading ability in Norwegian dyslexic children. The study was conducted as a pre-post intervention multiple case design with 5 participants, aged 14-15 years. The intervention consisted of 25 sessions of neurofeedback, 15 Theta/Beta training and 10 individualized training mostly at language areas. The effect of intervention was measured by means of qEEG and Logos (Norwegian dyslexia test). The results showed improvement in reading ability and phonological skills among all participants. Furthermore, qEEG analysis showed some changes in theta, alpha and beta activity in several brain areas. The results also confirm the heterogeneity of dyslexia, and the complicity of many brain areas that are involved in dyslexia. This study is limited by the small number of participants, and low control of other variables that may have an effect on the reading ability. The improvements in reading and phonological skills in this study suggest that further research in this area, with larger sample and several training sessions, is highly required.
Endosomal sorting by Semaphorin 4A in retinal pigment epithelium supports photoreceptor survival (2012)

Photoreceptor cell death is the hallmark of a group of human inherited retinal degeneration. Although the causative genetic mutations are often known, the mechanisms leading to photoreceptor degeneration remain poorly defined. Here, we show that Semaphorin 4A (Sema4A), a member of axonal guidance molecule semaphorin, plays a role in Rab11/FIP2-mediated endosomal sorting in retinal pigment epithelial cells to support photoreceptor function. In response to oxidative stress, Sema4A switches the endosomal sorting of the lysosomal precursor protein prosaposin from the lysosome to the exosomal release, which prevents light-induced photoreceptor apoptosis. In the absence of oxidative stress, Sema4A sorts retinoid-binding proteins with retinoids between the cell surface and endoplasmic reticulum, by which 11-cis-retinal, a chromophore for phototransduction, is regenerated and transported back to photoreceptors. Owing to defects in these processes, Sema4A-deficient mice exhibit marked photoreceptor degeneration. Our findings therefore indicate that Sema4A regulates two distinct endosomal-sorting pathways that are critical for photoreceptor survival and phototransduction during the transition between daylight and darkness.
N-acetylserotonin reduces lipopolysaccharide-induced lipid peroxidation in vitro more effectively than melatonin. (2010)

The results of the reported study clearly indicate that N-acetylserotonin is a much stronger antioxidant in vitro than melatonin in terms of reducing oxidative damage to lipid membranes. However, it remains still unclear how the features relate to in vivo circumstances.
Regioselective Synthesis of Indenols via Nickel-Catalyzed Carbocyclization Reaction (2003)

2-Halophenyl ketones 1a-e (1a, o-IC(6)H(4)COCH(3)) undergo carbocyclization with alkyl propiolates (2a, CH(3)(CH(2))(4)C[triple bond]CCO(2)CH(3); 2b, TMSC[triple bond]CCO(2)Et 2c, CH(3)C[triple bond]CCO(2)CH(3); 2d, CH(3)OCH(2)C[triple bond]CCO(2)CH(3); 2e, CH(3)(CH(2))(3)C[triple bond]CCO(2)CH(3); 2f, PhC[triple bond]CCO(2)CH(3); and 2g, (CH(3))(3)C[triple bond]CCO(2)CH(3)) in the presence of Ni(dppe)Br(2) and zinc powder in acetonitrile at 80 degrees C to afford the corresponding indenol derivatives 3a-m with remarkable regioselectivity in good to excellent yields. The nickel-catalyzed carbocyclization reaction was successfully extended to other simple disubstituted alkynes. Thus, the reaction of 2-halophenyl ketones 1a-e with disubstituted alkynes (2h, PhC[triple bond]CPh; 2i, CH(3)C(6)H(4)C[triple bond]CC(6)H(4)CH(3); 2j, CH(3)CH(2)C[triple bond]CCH(2)CH(3); 2k, PhC[triple bond]CCH(3); 2l, TMSC[triple bond]CCH(3); and 2m, PhC[triple bond]C(CH(2))(3)CH(3)) proceeded smoothly to afford the corresponding indenols 4a-t in good to excellent yields. For unsymmetrical alkynes 2k-m, the carbocyclization gave two regioisomers with regioselectivities ranging from 1:2 to 1:12 depending on the substituents on the alkyne and on the aromatic ring of halophenyl ketone. A possible mechanism for this nickel-catalyzed carbocyclization reaction is also proposed.
Protease activated receptor 2 controls myelin development, resiliency and repair (2017)

Oligodendrocytes are essential regulators of axonal energy homeostasis and electrical conduction and emerging target cells for restoration of neurological function. Here we investigate the role of protease activated receptor 2 (PAR2), a unique protease activated G protein-coupled receptor, in myelin development and repair using the spinal cord as a model. Results demonstrate that genetic deletion of PAR2 accelerates myelin production, including higher proteolipid protein (PLP) levels in the spinal cord at birth and higher levels of myelin basic protein and thickened myelin sheaths in adulthood. Enhancements in spinal cord myelin with PAR2 loss-of-function were accompanied by increased numbers of Olig2- and CC1-positive oligodendrocytes, as well as in levels of cyclic adenosine monophosphate (cAMP), and extracellular signal related kinase 1/2 (ERK1/2) signaling. Parallel promyelinating effects were observed after blocking PAR2 expression in purified oligodendrocyte cultures, whereas inhibiting adenylate cyclase reversed these effects. Conversely, PAR2 activation reduced PLP expression and this effect was prevented by brain derived neurotrophic factor (BDNF), a promyelinating growth factor that signals through cAMP. PAR2 knockout mice also showed improved myelin resiliency after traumatic spinal cord injury and an accelerated pattern of myelin regeneration after focal demyelination. These findings suggest that PAR2 is an important controller of myelin production and regeneration, both in the developing and adult spinal cord.
Expression and Bactericidal Activity of Nitric Oxide Synthase in<i>Brucella suis</i>-Infected Murine Macrophages (1998)

We examined the expression and activity of inducible nitric oxide synthase (iNOS) in both gamma interferon (IFN-gamma)-treated and untreated murine macrophages infected with the gram-negative bacterium Brucella suis. The bacteria were opsonized with a mouse serum containing specific antibrucella antibodies (ops-Brucella) or with a control nonimmune serum (c-Brucella). The involvement of the produced NO in the killing of intracellular B. suis was evaluated. B. suis survived and replicated within J774A.1 cells. Opsonization with specific antibodies increased the number of phagocytized bacteria but lowered their intramacrophage development. IFN-gamma enhanced the antibrucella activity of phagocytes, with this effect being greater in ops-Brucella infection. Expression of iNOS, interleukin-6, and tumor necrosis factor alpha (TNF-alpha) mRNAs was induced in both c-Brucella- and ops-Brucella-infected cells and was strongly potentiated by IFN-gamma. In contrast to that of cytokine mRNAs, iNOS mRNA expression was independent of opsonization. Similar levels of iNOS mRNAs were expressed in IFN-gamma-treated cells infected with c-Brucella or ops-Brucella; however, expression of iNOS protein and production of NO were detected only in IFN-gamma-treated cells infected with ops-Brucella. These discrepancies between iNOS mRNA and protein levels were not due to differences in TNF-alpha production. The iNOS inhibitor N omega-nitro-L-arginine methyl ester increased B. suis multiplication specifically in IFN-gamma-treated cells infected with ops-Brucella, demonstrating a microbicidal effect of the NO produced. This observation was in agreement with in vitro experiments showing that B. suis was sensitive to NO killing. Together our data indicate that in B. suis-infected murine macrophages, the posttranscriptional regulation of iNOS necessitates an additive signal triggered by macrophage Fcgamma receptors. They also support the possibility that in mice, NO favors the elimination of Brucella, providing that IFN-gamma and antibrucella antibodies are present, i.e., following expression of acquired immunity.
Improved near-infrared sensitivity of a back-side illuminated image sensor with a metal reflector (2009)

To improve the near-infrared sensitivity of an image sensor that has a conventional pixel structure, we made use of the metal wiring layer as a reflector in addition to the method of back-side illumination from the etched back surface of the sensor. We fabricated an image sensor that has a remaining silicon substrate thickness of 32 ± 4µm and evaluated the spectral sensitivity. For 830nm light, the sensitivity is about the same as for front-side illumination. For a wavelength of 970nm, the sensitivity was 2.2 times as high as for front-side illumination. The image sensor with reflector has about 30% higher sensitivity than without the reflector.
Geometrical Representation of Gaussian Beam Propagation (1966)

A single equation governing the various properties encountered in propagation of Gaussian beams is discussed. These characteristics may be graphically presented on an impedance chart such as a Smith chart or in the form of normalized curves. The geometrical representations highlight the relation between Gaussian mode theory and geometrical optics formulas. The power coupling coefficient between two Gaussian modes suggests a complex mismatch coefficient whose geometrical representation is essentially the same as that of a complex reflection coefficient in transmission-line theory. Application of the Smith chart in determining a complex mismatch coefficient is illustrated by graphical solution of a beam-matching problem.
XOgastan: XML-oriented gcc AST analysis and transformations (2004)

Software maintenance, program analysis and transformation tools almost always rely on static source code analysis as the first and fundamental step to gather information. In the past, two different strategies have been adopted to develop tool suites. There are tools encompassing or implementing the source parse step, where the parser is internal to the toolkit, developed and maintained with it. A different approach builds tools on the top of external, already available, components such as compilers that output the abstract syntax tree, or make it available via an API. We present an approach and a tool, XOgastan, developed exploiting the gcc/g++ ability to save a representation of the intermediate abstract syntax tree into a file. XOgastan translates the gcc/g++ format into a graph exchange language representation, thus taking advantage of the high number of currently available XML tools for the subsequent analysis phases. The tool is illustrated and its design is discussed, showing its architecture and the main implementation choices.
Dual junction GaInP/GaAs solar cells grown on metamorphic SiGe/Si substrates with high open circuit voltage (2006)

Dual junction GaInP/GaAs solar cells have been grown and fabricated on Si substrates using relaxed, compositionally graded SiGe buffer layers that provide a nearly lattice-matched low threading dislocation Ge surface for subsequent cell growth. The dual junction cells on SiGe/Si displayed high open circuit voltages in excess of 2.2 V, compared to 2.34 V for control cells on GaAs, that are consistent with maintaining the 1.8/spl times/10/sup 6/ cm/sup -2/ threading dislocation density throughout the cell structure. Even with total current output limited by large grid coverage and high reflectance, total area AM1.5G efficiency is 16.8%, with active area efficiency at 18.6%. The high V/sub oc/ establishes that SiGe metamorphic buffers are viable for integrating III-V multijunction cells on Si in a monolithic process.
An algorithm for compensating secondary currents of current transformers (1997)

Current transformer (CT) saturation may cause power system relays to malfunction. The conventional method used to deal with the problem is overdimensioning of the transformer core so that CTs can carry up to 20 times the rated current without exceeding 10% ratio correction. However, this not only reduces the sensitivity of power system relays, but also increases the CT core size. This paper presents a technique of estimating the secondary current corresponding to the CT ratio under CT saturation. The proposed algorithm can improve the sensitivity of relays to low level internal faults, minimize the instability of relays for external faults, and might ultimately assist in reducing the dimension of the required CT core cross-section.
Optimizing Customer-Agent Interactions with Natural Language Processing and Machine Learning (2019)

Efficient and successful customer service is an integral aspect of all businesses. In 2017, U.S. businesses lost $75 billion through poor customer service, where customers encountered unhelpful staff or spent too much time on unresolved issues. Customer experience management software companies analyze call center customer-agent transcriptions using methods such as sentiment analysis and topic modeling to improve their clients' customer service. However, these approaches are not optimized to account for the sequential nature of these customer-agent interactions. For example, while it is important to know how many customers cancel a service, businesses also need to understand how agents respond to a cancellation request and how certain actions may lead to a positive or negative outcome. To analyze the progression of conversations and understand actions that maximize positive outcomes, our research represents each contact center dialogue as a Markov decision process (MDP). For each conversation, we annotated whether the problem was resolved and whether the outcome was good or bad from a business perspective. We employed natural language processing (NLP) to extract the customer states and agent actions from call transcriptions. Our results identify and visualize the most frequent transcription sequences from successful conversations and estimate the expected probability of an outcome when an agent takes an action given a certain customer state. Such an approach may be used to develop programs to train agents for improved customer service in call centers.
Polyethylene solidification of low-level wastes (1985)

This topical report describes the results of an investigation on the solidification of low-level radioactive waste in polyethylene. Waste streams selected for this study included those which result from advanced volume reduction technologies (dry evaporator concentrate salts and incinerator ash) and those which remain problematic for solidification using contemporary agents (ion exchange resins). Four types of commercially available low-density polyethylenes were employed which encompass a range of processing and property characteristics. Process development studies were conducted to ascertain optimal process control parameters for successful solidification. Maximum waste loadings were determined for each waste and polyethylene type. Property evaluation testing was performed on laboratory-scale specimens to assess the potential behavior of actual waste forms in a disposal environment. Waste form property tests included water immersion, deformation under compressive load, thermal cycling and radionuclide leaching. Recommended waste loadings of 70 wt % sodium sulfate, 50 wt % boric acid, 40 wt % incinerator ash, and 30 wt % ion exchange resins, which are based on process control and waste form performance considerations are reported. 37 refs., 33 figs., 22 tabs.
Development and evaluation of antimicrobial natamycin‐incorporated film in gorgonzola cheese conservation (2006)

Abstract Conservation of food products depends on product quality and packaging suitability. The objective of this work was to develop and evaluate the antimicrobial efficiency of natamycin‐incorporated film in the production process of Gorgonzola cheese. It aims to optimize the production process and increase shelf‐life and food safety for the consumer. Films with different concentrations of natamycin were produced and tested in Gorgonzola cheeses to evaluate its efficiency against Penicillium roqueforti on the cheese surface. Films with 2 and 4% natamycin presented satisfactory results for fungus inhibition and the amount of natamycin released to the cheese was below that allowed by the legislation. Copyright © 2006 John Wiley & Sons, Ltd.