gebhart/patrepeval huggingface dataset:
CAP3: A Cloud Auto-Provisioning Framework for Parallel Processing Using On-Demand and Spot Instances (2013)

Cloud computing has drawn increasing attention from the scientific computing community due to its ease of use, elasticity, and relatively low cost. Because a high-performance computing (HPC) application is usually resource demanding, without careful planning, it can incur a high monetary expense even in Cloud. We design a tool called CAP3 (Cloud Auto-Provisioning framework for Parallel Processing) to help a user minimize the expense of running an HPC application in Cloud, while meeting the user-specified job deadline. Given an HPC application, CAP3 automatically profiles the application, builds a model to predict its performance, and infers a proper cluster size that can finish the job within its deadline while minimizing the total cost. To further reduce the cost, CAP3 intelligently chooses the Cloud's reliable on-demand instances or low-cost spot instances, depending on whether the remaining time is tight in meeting the application's deadline. Experiments on Amazon EC2 show that the execution strategy given by CAP3 is cost-effective, by choosing a proper cluster size and a proper instance type (on-demand or spot).
Update on the treatment of type 2 diabetes mellitus (2016)

To achieve good metabolic control in diabetes and keep long term, a combination of changes in lifestyle and pharmacological treatment is necessary. Achieving near-normal glycated hemoglobin significantly, decreases risk of macrovascular and microvascular complications. At present there are different treatments, both oral and injectable, available for the treatment of type 2 diabetes mellitus (T2DM). Treatment algorithms designed to reduce the development or progression of the complications of diabetes emphasizes the need for good glycaemic control. The aim of this review is to perform an update on the benefits and limitations of different drugs, both current and future, for the treatment of T2DM. Initial intervention should focus on lifestyle changes. Moreover, changes in lifestyle have proven to be beneficial, but for many patients is a complication keep long term. Physicians should be familiar with the different types of existing drugs for the treatment of diabetes and select the most effective, safe and better tolerated by patients. Metformin remains the first choice of treatment for most patients. Other alternative or second-line treatment options should be individualized depending on the characteristics of each patient. This article reviews the treatments available for patients with T2DM, with an emphasis on agents introduced within the last decade.
Matrix Protein Gene Variants of Two Distinct Serotypes of rVSV Make Effective Viral Vectors for Prime-Boost Vaccination (2016)

Recently, we developed attenuated VSV vectors by introducing temperature sensitive (ts) mutations in the M gene in both VSV Indiana and New Jersey serotypes. The newly generated M gene mutants of rVSV vectors are rVSVInd(GML) with mutations of G21E, M51R, and L111F, rVSVNJ(GMM) with mutations of G22E, M48R, and M51R, and rVSVNJ(GMML) with mutations of G22E, M48R, M51R, and L110F. Our purpose was to examine the immunogenicity of the new ts M gene mutant of rVSVInd and attenuated M gene mutants ofrVSVNJas vaccine vectors against HIV-1 proteins. We generated attenuated rVSVs carrying HIV-1 gag, pol, and env genes. We immunized mice with various prime-boost vaccination regimens. CD8+ T cell responses and humoral immune responses in the vaccinated mice were examined. Priming with rVSVInd(GML)-gag, pol, or env gene of HIV-1 and boosting with rVSVNJ(GMM)-gag, pol, or env gene or rVSVNJ(GMML)-gag, pol, or env gene induced the strongest CD8+ cytotoxic T cell responses against the HIV-1 Gag, RT, and Env proteins. The same vaccination regimen also induced strong humoral immune responses against the HIV-1 Gag and Env proteins. We conclude that rVSVInd(GML) priming followed by rVSVNJ(GMM) boosting is the best vaccination regimen for optimum B cell and T cell adaptive immune responses against inserted foreign gene products when the newly attenuated rVSVInd and rVSVNJ are used.
Three-Dimensional Vectorcardiography (3-D VCG) by Computer Graphics in Old Myocardial Infarction (1987)

By using computer graphics we rotated the vector loop and three coordinate axes to find the viewpoint where the infarctional changes are maximally exposed and demonstrated the advantage of the "3-D VCG" over the conventional VCG by defining the quantitative "MI index." The orthogonal electrocardiogram recorded by the Frank lead system was digitally measured and processed by a microcomputer. The loops and axes were rotated about the X axis (X-rot) and the Y axis (Y-rot). The spatial vector loop and orthogonal coordinates can be presented as viewed from any spheric direction. Eight quadrants were illustrated with four colors and red circles. The subjects consisted of 30 patients with old anterior myocardial infarction (MI) and 15 patients with old inferior MI. We measured the area of "Bite" in anterior MI and superior displacement in inferior MI. The MI index was defined and averaged in 361 directions. In anterior MI, the maximum mean index was obtained when X-rot is +90 degrees and Y-rot -40 degrees, viewed from upward and leftward, whereas in inferior MI it was obtained when X-rot is -50 degrees and Y-rot -80 degrees, viewed from downward and leftward. These values were significantly higher than those in conventional VCG projections, substantiating superior diagnostic sensitivity of 3-D VCG.
Suppression of Acid Sphingomyelinase Protects the Retina from Ischemic Injury (2016)

Our results demonstrate that reducing ASMase expression provides partial protection from ischemic injury. Hence, the production of ceramide and subsequent mediators plays a role in the development of ischemic retinal injury. Modulating ASMase may present new opportunities for adjunctive therapies when treating retinal ischemic disorders.
A simple theory of magnetic insulation from basic physical considerations (1983)

Most of the observed features of magnetically insulated transmission lines are derived from the simple considerations of pressure balance and the space-charge flow limit. These include the mean electron drift velocity and the relationship between line voltage and the currents in the positive and negative lines. This voltage-current relationship is compared with experimental data.
Using LinkedIn (2010)

Using LinkedIn is a customized, media-rich learning experience designed to help new users master LinkedIn quickly, and get the most out of it, fast! It starts with a concise, friendly, straight-to-the-point guide to LinkedIn. This book is fully integrated with an unprecedented collection of online learning resources: more than 60 video and audio tutorials as well as additional web content, all designed to reinforce key concepts and help you achieve real mastery. The book and online content work together to teach everything mainstream LinkedIn users need to know. This practical, approachable coverage guides you through mastering LinkedIn topics including: Creating a profile that achieves targeted goalsFinding jobs, consulting opportunities, and clients on LinkedInRecruiting job candidatesDeveloping a streamlined approach for managing contactsCustomizing LinkedIn for maximum effectivenessUsing LinkedIn Answers and Groups for research and marketingExtending the power of LinkedIn with applications and toolsBecoming a LinkedIn service providerAccessing LinkedIn from mobile devicesAdvertising on LinkedIn
Intracellular Signaling Pathways Activated by Neurotrophic Factors (1996)

The brain's default mode network consists of discrete, bilateral and symmetrical cortical areas, in the medial and lateral parietal, medial prefrontal, and medial and lateral temporal cortices of the human, nonhuman primate, cat, and rodent brains. Its ...Read More
Duplicate a key using image processing (2008)

This paper proposes to use image processing to duplicate a key grooves and a key cuts [1]. The first step of this research is taking a cross-sectional image of the key grooves and top-sectional image the key cuts. Exploiting binary image enhancement to acquire a contour of the key grooves and key cuts. Then transform the image data to contour data presented by coordinate(x,y). This information is transformed into CNC G Coding . The duplication of the key will be performed by mini CNC machine. The tolerance examination is conducted by comparing a dimension of the master key and the duplicated key.
An Experimental Investigation of Showerhead Film Cooling Performance on a Turbine Blade (2015)

Experimental tests were performed to investigate the film cooling performance at the leading edge region of a turbine blade using the Infrared Radiation (IR) thermography technique. The test blades were enlarged by five times the natural size with three showerhead rows of radial-angle hole and one row of streamwise angle hole on pressure and suction side, respectively. Six different leading edge cooling geometries were designed by varying the radial angle from 35°to 90°. The effects of mainstream Reynolds number and coolant-to-mainstream blowing ratio were discussed. Results show that the blowing ratio has a marked influence on the cooling effectiveness with the existence of an optimum blowing ratio. High mainstream Reynolds number produces larger coolant flow rate and hence better cooling effectiveness. For x/C<0.15 on suction side close to the stagnation region and the overall pressure side, small radial angle improves the leading edge film cooling performance,whereas large radial angle facilitates the effectiveness downstream of x/C>0.15 on suction side. In current investigation, 45° showerhead radial angle relatively produces the least pressure loss and 75° or 90° gives the most aerodynamic loss that increases with the blowing ratio.
Mannose/Glucose-Functionalized Dendrimers To Investigate the Predictable Tunability of Multivalent Interactions (2005)

G4-, G5-, and G6-PAMAM dendrimers were functionalized with mixtures of mannose and glucose in varying ratios, and the relative affinities of these compounds for Concanavalin A (Con A) were evaluated using the hemagglutination assay. As the ratio of mannose to glucose increases, the relative activity in the hemagglutination assay (on a per sugar basis) increases linearly. Methyl mannose binds to Con A with an affinity 4-fold higher than that of methyl glucose; multivalency amplifies this trend. The mannose/glucose-functionalized dendrimer results reported here suggest that the affinity of multivalent associations can be attenuated in predictable, reliable ways based on monovalent affinities of the ligands.
Eggshell and environmental bacteria contribute to the intestinal microbiota of growing chickens (2020)

We identified distinct intestinal microbial communities and differing cecal short-chain fatty acid profiles between birds exposed to the microbiota associated with either the eggshell or environment, and those of conventionally hatched birds. Our data suggest the eggshell plays an appreciable role in the development of the chicken intestinal microbiota, especially in the jejunum and ileum where the community structure of the eggshell-only birds was similar to the structure of conventionally hatched birds. Our data identify a complex interplay between the eggshell and environmental microbiota during establishment and succession within the chicken gut. Further studies should explore the ability of eggshell- and environment-derived microbes to shape the dynamics of succession and how these communities can be targeted through interventions to promote gut health and mitigate food-borne pathogen colonization in poultry.
“Potential Health Benefits of Lunasin: A Multifaceted Soy‐Derived Bioactive Peptide” (2015)

Bioactive peptides are small protein fragments derived from enzymatic hydrolysis of food proteins, fermentation with proteolytic starter cultures, and gastrointestinal digestion. These peptides have positive impacts on a number of physiological functions in living beings. Lunasin, a soy-derived bioactive peptide, is one of the most promising among them. Lunasin encoded within 2S albumin (GM2S-1) gene, identified as a novel peptide extracted from soybean seed. It is composed of 43 amino acid residues with a molecular weight of 5.5 kDa. Extensive scientific studies have shown that lunasin possesses inherent antioxidative, anti-inflammatory, anticancerous properties and could also play a vital role in regulating of cholesterol biosynthesis in the body. Its high bioavailability and heat stable nature allow its potential use as dietary supplement. The present review summarizes some of the potential health and therapeutic benefits of lunasin reported hitherto.
Metadata Service for Random Frame Reading of Video Stored in Distributed File System (2017)

Aiming at solving the problem in video processing for the distributed storage of massive video, this paper presents a high performance video frame random access service based on Hadoop Distributed File System(HDFS).
An Energy Strategy for Canada (2017)

Canada is struggling to fully develop, sell and move its energy resources. This is a dramatic change from the recent past where the U.S. has provided stable growth in demand for energy supplied by the provinces, from hydrocarbons to electricity. Current circumstances now challenge this relationship, adding environmental, policy and economic hurdles that exacerbate the impact of fluctuations in world demand and pricing. In addition, competitive interaction between provinces, aboriginal land owners and special interest groups complicate and compound the issues of royalty returns, regulatory authority and direction, land-use management and long-term market opportunities for Canadian companies. There is no strategic document guiding the country’s energy future. As the steward of one of the largest, most diverse and valuable energy "banks" in the world, Canada has a unique opportunity to exploit a critical and valuable economic niche in the world economy. Given the lack of federal leadership and the tendency for each province to undercut each other in the same marketplace, there is also the distinct possibility the nation will squander the opportunity. This document offers the rationale for a comprehensive energy strategy, literally a vision where Canada can lead and not follow opportunities in energy markets. This strategic approach to energy systems by definition will include transportation, housing, employment and financial markets. It is not a plan, not a foil for tax or policy guidance in one or more sectors. This strategy is a fundamental rail on which plans, tactics and policies can be built. This vision identifies how the provinces can work together using all the tools available to them, maximizing long-term resource development while minimizing environmental damage. This document assumes there can be a broad commitment and effort by the federal government to help build those tools, providing guidance and assistance where needed without obstructing or denying the fundaments of the Canadian Constitution, First Nations people, and the role of provinces in managing the resources within their borders. This recommended energy strategy highlights changes occurring in world markets that threaten successful, coherent energy policy development in the absence of a unifying strategy. This strategy highlights the need to look ahead, understand these changes, and create adaptive, unifying processes that will provide longterm economic and geopolitical stability using energy as the common denominator for Canada's future.
Oil‐Impregnated Nanoporous Oxide Layer for Corrosion Protection with Self‐Healing (2017)

The major drawback of current passivation techniques for preventing corrosion is the lack of ability to withstand any external damages or local defects. In this study, oil‐impregnated nanoporous anodic aluminum oxide (AAO) layers are investigated to overcome such limitations and thus advance corrosion protection. By completely filling hydrophobized nanopores with oil via a solvent exchange method, a highly water‐repellent surface that prevents the penetration of corrosive media into the AAO layer and hence the corrosion of aluminum is achieved. The impregnation of oil into the hydrophobic nanoporous AAO layer enhances the corrosion resistance of an AAO layer by two and four orders of magnitude compared to that of a hydrophobic (i.e., air‐entrained) and a bare (hydrophilic) AAO, respectively. In the presence of local defects, the oil impregnated within the hydrophobic nanoporous AAO layer naturally permeates into the defects and ultimately inhibits the exposure of the aluminum surface to corrosive media. Whereas the corrosion current density of the air‐entrained hydrophobic AAO layer increases by more than 30 times after cracks, that of the oil‐impregnated AAO layer increases by no more than 4 times, showing superior anticorrosion property even after there are cracks, owing to the effective self‐healing capability.
Risk markers associated with challenging behaviours in people with intellectual disabilities: a meta‐analytic study (2003)

A meta-analysis of prevalence and cohort studies conducted over the last 30 years was carried out to identify risk markers for challenging behaviour shown by individuals with intellectual disabilities (IDs). A total of 86 potential studies was identified from the review, with 22 (25.6%) containing sufficient data to enable a statistical analysis to be conducted. Results indicated that males were significantly more likely to show aggression than females, and that individuals with a severe/profound degree of ID were significantly more likely to show self-injury and stereotypy than individuals with a mild/moderate degree of ID. Individuals with a diagnosis of autism were significantly more likely to show self-injury, aggression and disruption to the environment whilst individuals with deficits in receptive and expressive communication were significantly more likely to show self-injury. In most cases, tests for heterogeneity were statistically significant, as expected. The meta-analysis highlighted the paucity of methodologically robust studies of risk markers for challenging behaviours and the lack of data on incidence, prevalence and chronicity of challenging behaviour in this population.
Relevance of mask-roughness-induced printed line-edge roughness in recent and future extreme-ultraviolet lithography tests (2004)

The control of line-edge roughness (LER) of features printed in photoresist poses significant challenges to next-generation lithography techniques such as extreme-ultraviolet (EUV) lithography. Achieving adequately low LER levels requires accurate resist characterization as well as the ability to separate resist effects from other potential contributors to LER. One potentially significant contributor to LER arises from roughness on the mask coupling to speckle in the aerial image and consequently to LER in the printed image. Here I numerically study mask surface roughness and phase roughness to resist LER coupling both as a function of illumination coherence and defocus. Moreover, the potential consequences of this mask effect for recent EUV lithography experiments is studied through direct comparison with experimental through-focus printing data collected at a variety of coherence settings. Finally, the effect that mask roughness will play in upcoming 0.3-numerical-aperture resist testing is considered.
Surgical management of airway obstructions during sleep (1977)

Anatomical or physiological airway obstructions during sleep, of which the patient is unaware, cause daytime sleepiness at first, then signs of decreasing mental function, and eventually in some individuals, pulmonary and systemic hypertension. A few of these patients had been recognized before, the Pickwickian syndrome and in children with cardiac problems and large tonsils. The majority, however, present as sleep disorders. This paper describes our surgical experience with improving the airways of 19 children and adults with daytime somnolence.
Investigation on Beamspace Multiple-Input Multiple-Output Synthetic Aperture Radar Data Imaging (2016)

The multiple-input multiple-output (MIMO) technique can improve the high-resolution wide-swath imaging capacity of synthetic aperture radar (SAR) systems. Beamspace MIMO-SAR utilizes multiple subpulses transmitted with different time delays by different transmit beams to obtain more spatial diversities based on the relationship between the time delay and the elevation angle in the side-looking radar imaging geometry. This paper presents a beamspace MIMO-SAR imaging approach, which takes advantage of real time digital beamforming (DBF) with null steering in elevation and azimuth multichannel raw data reconstruction. Echoes corresponding to different subpulses in the same subswath are separated by DBF with null steering onboard, while echoes received and stored by different azimuth channels are reconstructed by multiple Doppler reconstruction filters on the ground. Afterwards, the resulting MIMO-SAR raw data could be equivalent to the raw data of the single-channel burst mode, and classical burst mode imaging algorithms could be adopted to obtain final focused SAR images. Simulation results validate the proposed imaging approach.
Language-agnostic BERT Sentence Embedding (2022)

While BERT is an effective method for learning monolingual sentence embeddings for semantic similarity and embedding based transfer learning (Reimers and Gurevych, 2019), BERT based cross-lingual sentence embeddings have yet to be explored. We systematically investigate methods for learning multilingual sentence embeddings by combining the best methods for learning monolingual and cross-lingual representations including: masked language modeling (MLM), translation language modeling (TLM) (Conneau and Lample, 2019), dual encoder translation ranking We show that introducing a pre-trained multilingual language model dramatically reduces the amount of parallel training data required to achieve good performance by 80%. Composing the best of these methods produces a model that achieves 83.7% bi-text retrieval accuracy over 112 languages on Tatoeba, well above the 65.5% achieved by Artetxe and Schwenk (2019b), while still performing competitively on monolingual transfer learning benchmarks Parallel data mined from CommonCrawl using our best model is shown to train competitive NMT models for en-zh and en-de. We publicly release our best multilingual sentence embedding model for 109+ languages at https://tfhub.dev/ google/LaBSE.
Dnm1p Gtpase-Mediated Mitochondrial Fission Is a Multi-Step Process Requiring the Novel Integral Membrane Component Fis1p (2000)

Yeast Dnm1p is a soluble, dynamin-related GTPase that assembles on the outer mitochondrial membrane at sites where organelle division occurs. Although these Dnm1p-containing complexes are thought to trigger constriction and fission, little is known about their composition and assembly, and molecules required for their membrane recruitment have not been isolated. Using a genetic approach, we identified two new genes in the fission pathway, FIS1 and FIS2. FIS1 encodes a novel, outer mitochondrial membrane protein with its amino terminus exposed to the cytoplasm. Fis1p is the first integral membrane protein shown to participate in a eukaryotic membrane fission event. In a related study (Tieu, Q., and J. Nunnari. 2000. J. Cell Biol. 151:353-365), it was shown that the FIS2 gene product (called Mdv1p) colocalizes with Dnm1p on mitochondria. Genetic and morphological evidence indicate that Fis1p, but not Mdv1p, function is required for the proper assembly and distribution of Dnm1p-containing fission complexes on mitochondrial tubules. We propose that mitochondrial fission in yeast is a multi-step process, and that membrane-bound Fis1p is required for the proper assembly, membrane distribution, and function of Dnm1p-containing complexes during fission.