gebhart/patrepeval huggingface dataset:
Bootstrapping Dialog Models from Human to Human Conversation Logs (2021)

State-of-the-art commercial dialog platforms provide powerful tools to build a conversational agent. These platforms provide complete control to the dialog designer to model user-agent interactions. However, a dialog designer needs to rely on domain experts to manually build the dialog model -- by creating dialog flow nodes and modeling user intents. This process is laborious, time consuming and expensive and does not allow the designer to exploit human to human conversation logs effectively. In this work, we present a research prototype that can ingest human-to-human conversation logs between an end-user and an agent, and suggest user-intents and agent-responses, given a conversation context. We utilize human to human conversation logs to build two emulators: user and agent. An agent emulator models an agent response given the conversation context so far, and a user emulator outputs possible user responses. Our system is able to recommend conversational intents as well as conversation flow using emulators based on real-world data, thus making the process of designing a bot more efficient. To the best our knowledge this is the first system that enables data-driven dialog model creation by emulating users and agents.
<title>Low bit rate with excellent image reconstruction capability by adaptive multiresolution code books in vector quantization</title> (1997)

Despite superior performance of vector quantization (VQ) over scalar quantization in providing low bit rates at optimized distortion, the complexities involved in the encoding processes namely search processes and in generation of efficient code books in VQ prohibit the use of VQ in many applications. We introduce a new VQ technique with optimized search processes and distortion measures followed by entropy coding thereby yielding exceptionally low bit rates yet high visual quality for a large class of images including a variety of medical images with potential application in cost-effective telecommunications. A new approach to vector quantization by integrated self-organizing neural networks with fuzzy distortion measures has been applied to generate multiresolution codebooks from wavelet decomposed images. Two adaptive clustering techniques, namely integrated adaptive fuzzy clustering and adaptive fuzzy leader clustering with embedded fuzzy distortion measures, are used for partitioning similar vector groups for generating code books at each resolution level. The lower bound for the bits required to represent an image is given by its entropy. However, if the fundamental limit of compressing a signal can be related to perceptual entropy, then a bit rate lower than the entropy estimate can be achieved. The capability of this new approach to vector quantization resulting in low bit rate at high visual quality will have significant applications in telecommunications and telemedicine.
Mercury removal by thiol‐functionalized metal oxide–carbon black sorbent and mixed‐matrix membranes (2012)

Aqueous mercury sorption is achieved using a novel thiol‐functionalized metal oxide‐coated carbon sorbent. The material is hydrolytically and thermally stable (up to 250°C) because of the formation of covalent siloxane bonds on functionalization and increased hydrophobicity. The particles were synthesized with a variety of morphologies; the base particles are ∼80 nm and a nonuniform metal oxide (including silica) coating less than 5 nm thick. This sorbent material has a high equilibrium capacity for mercury (∼60 mg/g) at concentrations up to ∼150 mg/L. The Langmuir constant for equilibrium sorption ( k a / k d ) is K = 16.9 L/mol. Packed column experiments using real water reduced mercury levels to below detectable limits. Mixed‐matrix membranes (sorbent particles and polysulfone) were synthesized to combine the ease of surface functionalization on particles with advantages of polymer membranes. Membranes with up to 50 wt % particles were synthesized, with sorption capacities at 200 mg/g sorbent or greater due to dispersion of particles in the matrix and the use of small particles, which are impractical in packed column operations. A regeneration scheme is proposed using multifunctional particles (thiol and sulfonate moieties). Initial experiments showed that mild regeneration conditions (dilute HCl at pH 4) partially regenerated the sorbent particles. © 2012 American Institute of Chemical Engineers Environ Prog, 32: 705–714, 2013
Method and apparatus for determining the magnitude of components of measurements made from inside a borehole (1989)

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Automatic face location detection for model-assisted rate control in H.261-compatible coding of video (1995)

We present a novel and practical way to integrate techniques from computer vision to low bit-rate coding systems for video teleconferencing applications. Our focus is to locate and track the faces and selected facial features of persons in typical head-and-shoulders video sequences, and to exploit the location information in a ‘classical’ video coding/decoding system. The motivation is to enable the system to encode selectively various image areas and to produce perceptually pleasing coded images where faces are sharper. We refer to this approach—a mix of classical waveform coding and model—based coding-as model-assisted coding. We propose two totally automatic algorithms which, respectively, perform the detection of a head outline, and identify an ‘eyes-nose-mouth’ region, both from downsampled binary thresholded edge images. The algorithms operate accurately and robustly, even in cases of significant head rotation or partial occlusion by moving objects. We show how the information about face and facial feature location can be advantageously exploited by low bit-rate waveform-based video coders. In particular, we describe a method of object-selective quantizer control in a standard coding system based on motion-compensated discrete cosine transform—CCITT's recommendation H.261. The approach is based on two novel algorithms, namely buffer rate modulation and buffer size modulation. By forcing the rate control algorithm to transfer a fraction of the total available bit-rate from the coding of the non-facial to that of the facial area, the coder produces images with better-rendered facial features, i.e. coding artefacts in the facial area are less pronounced and eye contact is preserved. The improvement was found to be perceptually significant on video sequences coded at the ISDN rate of 64 kbps, with 48 kbps for the input (color) video signal in QCIF format.
Effective IPTV Channel Control Algorithm Supporting Smooth Channel Zapping (2010)

This paper presents an effective IPTV channel control algorithm considering network utilization and channel zapping time. The proposed algorithm keeps maximum average channel zapping time of each subscriber in the tolerable range with low network bandwidth usage by adjusting the type of each channel and the number of additional intra frames inserted into each channel. Finally, experimental results are provided to show the performance of the proposed algorithm.
Kaposi's sarcoma-associated herpesvirus encodes a functional cyclin (1997)

Kaposi's sarcoma-associated herpesvirus (KSHV) (also called human herpesvirus 8) is consistently found in Kaposi's sarcoma lesions and in body-cavity-based lymphomas. A 17-kb KSHV lambda clone was obtained directly from a Kaposi's sarcoma lesion. DNA sequence analysis of this clone identified an open reading frame which has 32% amino acid identity and 53% similarity to the virus-encoded cyclin (v-cyclin) of herpesvirus saimiri (HVS) and 31% identity and 53% similarity to human cellular cyclin D2. This KSHV open reading frame was shown to encode a 29- to 30-kDa protein with the properties of a v-cyclin. KSHV v-cyclin protein was found to associate predominantly with cdk6, a cellular cyclin-dependent kinase known to interact with cellular type D cyclins and HVS v-cyclin. The KSHV v-cyclin was also found to associate weakly with cdk4. KSHV v-cyclin-cdk6 complexes strongly phosphorylated glutathione S-transferase-Rb fusion protein and histone H1 as substrates in vitro. Thus, KSHV v-cyclin resembles the v-cyclin of the T-lymphocyte-transforming HVS in its specificity for association with cdk6 and in its ability to strongly activate cdk6 protein kinase activity.
Application of super capacitors for voltage regulation in aircraft distributed power systems (2002)

The feasibility of the use of a super capacitor and a DC-DC power converter to improve the regulation of the bus voltage of an aircraft is studied in this paper. A PWM boost DC-DC power converter is used to transfer the energy from the capacitor to the DC bus. A PWM buck DC-DC power converter is used to transfer the energy from the DC bus to the super capacitor. Experimental results indicate that a super capacitor and a DC-DC power converter can he used to improve the regulation of the DC bus voltage of distributed power systems.
Iterated denoising for image recovery (2003)

We propose an algorithm for image recovery where completely lost blocks in an image/video-frame are recovered using spatial information surrounding these blocks. Our primary application is on lost regions of pixels containing textures, edges and other image features that are not readily handled by prevalent recovery and error concealment algorithms. The proposed algorithm is based on the iterative application of a generic denoising algorithm and it does not necessitate any complex preconditioning, segmentation, or edge detection steps. Utilizing locally sparse linear transforms and overcomplete denoising, we obtain good PSNR performance in the recovery of such regions. In addition to results on image recovery, the paper provides further insights into the usefulness of popular transforms like wavelets, wavelet packets, discrete cosine transform (DCT) and complex wavelets in providing sparse image representations.
The Ionospheric Impact of the October 2003 Storm Event on WAAS (2004)

The United States Federal Aviation Administration's (FAA) Wide Area Augmentation System (WAAS) for civil aircraft navigation is focused primarily on the Conterminous United States (CONUS). Other Satellite- Based Augmentation Systems (SBAS) include the European Geostationary Navigation Overlay Service (EGNOS) and the Japanese Global Navigation Satellite System (MSAS). Navigation using WAAS requires accurate calibration of ionospheric delays. to provide delay corrections for single frequency GPS users, the wide area differential GPS systems depend upon accurate determination of ionospheric total electron content (TEC) along radio links. Dual frequency transmissions from GPS satellites have been used for many years to measure and map ionospheric TEX on regional and global scales.
Inactivation of Foot-and-Mouth Disease Virus Vaccine Strains by Activation of Virus-associated Endonuclease (1984)

A new inactivation process for foot-and-mouth disease virus (FMDV) has been developed. This process is based on the activation of the FMDV endonuclease by incubation of unfractionated viral suspension or purified virions at 37 degrees C in the presence of high concentrations of monovalent cations such as K+, Cs+ or NH4+ at pH 8.5. This procedure completely inactivated several FMDV vaccine strains yielding preparations having similar amounts of 140S particles to untreated controls. The inactivation followed first-order kinetics and the rate of inactivation was faster than that achieved with other agents, e.g. binary ethyleneimine. Testing in suckling mice or tissue culture revealed no residual infectivity after inactivation. Virus particles purified from inactivated preparations showed (i) the same sedimentation coefficient as non-inactivated preparations, (ii) electrophoretic patterns of their viral capsid proteins identical to those derived from non-inactivated preparations, and (iii) extensive degradation of the 35S viral RNA. This method is safer than inactivation with aziridines because only innocuous chemicals are used in the process.
Conservation of antigen components from two recombinant hybrid proteins protective against malaria (1993)

Recently, we have shown that two hybrid proteins carrying partial sequences of the blood-stage antigens SERP, HRPII, and MSAI from Plasmodium falciparum confer protective immunity on Aotus monkeys against an experimental parasite infection (B. Knapp, E. Hundt, B. Enders, and H. A. Küpper, Infect. Immun. 60:2397-2401, 1992). The malarial components of the hybrid proteins consist of amino acid residues 630 to 892 of SERP, amino acid residues 146 to 260 of MSAI, and the 189 C-terminal residues of HRPII. We have studied the diversity of these protein regions in field isolates of P. falciparum. Genomic DNA was extracted from the blood of six donors from two different areas where malaria is endemic. The gene regions of SERP and MSAI coding for the corresponding sequences of the protective hybrid proteins and the exon II region of the HRPII gene were amplified by polymerase chain reaction and sequenced. All three regions were found to be highly conserved. In the 262-amino-acid fragment of SERP, one single conservative amino acid substitution was found. The exon II region of HRPII showed only a slight variability in number and arrangement of the repeat units. The 115-amino-acid fragment of MSAI which is located within an N-terminal region known to be conserved among different parasite strains was shown to be the most variable among the vaccine components: amino acid substitutions were found in 14 different positions of this MSAI region when both laboratory strains and field isolates were compared.
Spectroscopic localization by simultaneous acquisition of the double‐spin and stimulated echoes (2014)

The advantages of STEAM can be augmented with the higher SNR of PRESS by combining the spin and stimulated echoes. Quantification, especially of J-coupled resonances and intermediate and long TEs, must be carefully considered.
Modular Battery Charge Controller (2009)

A new approach to masterless, distributed, digital-charge control for batteries requiring charge control has been developed and implemented. This approach is required in battery chemistries that need cell-level charge control for safety and is characterized by the use of one controller per cell, resulting in redundant sensors for critical components, such as voltage, temperature, and current. The charge controllers in a given battery interact in a masterless fashion for the purpose of cell balancing, charge control, and state-of-charge estimation. This makes the battery system invariably fault-tolerant. The solution to the single-fault failure, due to the use of a single charge controller (CC), was solved by implementing one CC per cell and linking them via an isolated communication bus [e.g., controller area network (CAN)] in a masterless fashion so that the failure of one or more CCs will not impact the remaining functional CCs. Each micro-controller-based CC digitizes the cell voltage (V(sub cell)), two cell temperatures, and the voltage across the switch (V); the latter variable is used in conjunction with V(sub cell) to estimate the bypass current for a given bypass resistor. Furthermore, CC1 digitizes the battery current (I1) and battery voltage (V(sub batt) and CC5 digitizes a second battery current (I2). As a result, redundant readings are taken for temperature, battery current, and battery voltage through the summation of the individual cell voltages given that each CC knows the voltage of the other cells. For the purpose of cell balancing, each CC periodically and independently transmits its cell voltage and stores the received cell voltage of the other cells in an array. The position in the array depends on the identifier (ID) of the transmitting CC. After eight cell voltage receptions, the array is checked to see if one or more cells did not transmit. If one or more transmissions are missing, the missing cell(s) is (are) eliminated from cell-balancing calculations. The cell-balancing algorithm is based on the error between the cell s voltage and the other cells and is categorized into four zones of operation. The algorithm is executed every second and, if cell balancing is activated, the error variable is set to a negative low value. The largest error between the cell and the other cells is found and the zone of operation determined. If the error is zero or negative, then the cell is at the lowest voltage and no balancing action is needed. If the error is less than a predetermined negative value, a Cell Bad Flag is set. If the error is positive, then cell balancing is needed, but a hysteretic zone is added to prevent the bypass circuit from triggering repeatedly near zero error. This approach keeps the cells within a predetermined voltage range.
Distributed network monitoring with bounded link utilization in IP networks (2003)

Designing optimal measurement infrastructure is a key step for network management. In this work we address the problem of optimizing a scalable distributed polling system. The goal of the optimization is to reduce the cost of deployment of the measurement infrastructure by identifying a minimum poller set subject to bandwidth constraints on the individual links. We show that this problem is NP-hard and propose three different heuristics to obtain a solution. We evaluate our heuristics on both hierarchical and flat topologies with different network sizes under different polling bandwidth constraints. We find that the heuristic of choosing the poller that can poll the maximum number of unpolled nodes is the best approach. Our simulation studies show that the results obtained by our best heuristic is close to the lower bound obtained using LP relaxation.
Thrombolysis: A Critical First-Line Therapy with an Unfulfilled Potential (2015)

A blood clot or thrombus triggers the onset of most vascular diseases, like stroke or heart attack. Thrombolysis is the only treatment that can restore blood flow rapidly and easily. Unfortunately, the standard thrombolytic, tissue plasminogen activator (tPA), has proven inadequate and is being replaced by invasive endovascular procedures, which are time consuming and limited in their availability in relation to the scope of the problem. Historically, when tPA clinical trials began, it was not recognized sufficiently that without the other natural plasminogen activator, prourokinase (proUK), thrombolysis by tPA was seriously compromised. The reason is that the 2 activators have complementary mechanisms of action in fibrinolysis, making their combination a requirement for optimal efficacy and synergy. Biological fibrinolysis also uses both activators, explaining why such low endogenous concentrations are sufficient. A low-dose sequential combination of tPA and proUK was tested in acute myocardial infarction, where it was exceptionally effective and safe. Because native proUK at pharmacological doses was vulnerable to spontaneous conversion to urokinase, jeopardizing safety, a site-directed mutant was developed that improved proUK's plasma stability fivefold without interfering with its mode of action. Mini-bolus tPA followed by low-dose proUK infusion is a simple, safe, effective, and promising first-line treatment of acute thrombotic disorders.
Genome-wide association and prediction of direct genomic breeding values for composition of fatty acids in Angus beef cattlea (2013)

Further investigations are needed to identify the causal variants harbored within the identified 1-Mb windows. For the first time, Angus breeders have a tool whereby they could select for altered fatty acid composition. Furthermore, these reported results could improve our understanding of the biology of fatty acid metabolism and deposition.
Text-informed audio source separation using nonnegative matrix partial co-factorization (2013)

We consider a single-channel source separation problem consisting in separating speech from nonstationary background such as music. We introduce a novel approach called text-informed separation, where the source separation process is guided by the corresponding textual information. First, given the text, we propose to produce a speech example via either a speech synthesizer or a human. We then use this example to guide source separation and, for that purpose, we introduce a new variant of the nonnegative matrix partial co-factorization (NMPCF) model based on a so called excitation-filter-channel speech model. The proposed NMPCF model allows sharing the linguistic information between the example speech and the speech in the mixture. We then derive the corresponding multiplicative update (MU) rules for the parameter estimation. Experimental results over different types of mixtures and speech examples show the effectiveness of the proposed approach.
The Chlamydia trachomatis hyp operon is homologous to the groE stress response operon of Escherichia coli (1990)

The Chlamydia trachomatis serovar A hyp operon was cloned, sequenced, and expressed in Escherichia coli. Two cotranscribed open reading frames, hypA and hypB, encoded polypeptides of 17 and 57 kilodaltons, respectively. The deduced amino acid sequences of serovar A HypA and HypB proteins were (respectively) 85 and 94% identical with HypA and HypB proteins of Chlamydia psittaci GPIC, and HypB was greater than 50% identical to 60-kilodalton stress response proteins from other procaryotes and eucaryotes. The sequence should be useful in defining the antigenic structure of the Chlamydia trachomatis HypB protein, a necessary step toward understanding the relationship between the immune response to this protein and the pathogenesis of human chlamydial diseases.
Restoring connectivity in Wireless Sensor-Actor Networks with minimal node movement (2011)

In Wireless Sensor-Actor Networks (WSANs), sensors probe their surroundings and send their data to more capable actor nodes in order to execute an application task. The actors' response is mostly collaborative and requires them to coordinate their operation. Therefore, a strongly connected inter-actor topology would be necessary at all time and tolerance of an actor failure becomes a design requirement. Autonomous repositioning of actor nodes has been deemed as an effective recovery strategy. This paper presents a Least-Movement Topology Repair (LeMoToR) algorithm. LeMoToR is a distributed scheme that relies on the local view of a node about the network. To restore connectivity, LeMoToR strives to relocate the least number of nodes and reduce the traveled distance and message complexity. Unlike contemporary schemes that maintain 1 or 2-hop neighbor lists, LeMoToR utilizes existing path discovery activities in the network in order to know the structure of the topology and avoids imposing additional pre-failure communication overhead. The simulation results validate the effectiveness of LeMoToR.
Rapid One-Step <sup>18</sup>F-Labeling of Peptides via Heteroaromatic Silicon-Fluoride Acceptors (2020)

A new class of organosilicon-based radiosynthons, heteroaromatic silicon-fluoride acceptors, namely, HetSiFAs, that readily undergo isotope exchange with dry [<sup>18</sup>F]fluoride at room temperature in high radiochemical yield (up to 94%) with good molar activity is reported. Radiofluorination proceeds in a single step in 2 min without high-performance liquid chromatography purification to provide an operationally simple method for <sup>18</sup>F-PET tracer production. This method was used to prepare an <sup>18</sup>F-labeled commercial tetrapeptide, and positron emission tomography imaging confirmed <i>in vivo</i> stability.