gebhart/patrepeval huggingface dataset:
Microtacticity distribution of polypropylenes prepared with heterogeneous Ziegler-Natta catalysts (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMicrotacticity distribution of polypropylenes prepared with heterogeneous Ziegler-Natta catalystsMasahiro Kakugo, Tatsuya Miyatake, Yukio Naito, and Kooji MizunumaCite this: Macromolecules 1988, 21, 2, 314–319Publication Date (Print):February 1, 1988Publication History Published online1 May 2002Published inissue 1 February 1988https://pubs.acs.org/doi/10.1021/ma00180a006https://doi.org/10.1021/ma00180a006research-articleACS PublicationsRequest reuse permissionsArticle Views378Altmetric-Citations109LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Compile-time deallocation of individual objects (2006)

This paper presents a static analysis and transformation system that enables the deallocation of individual objects in Java programs. Given an input program, the compiler automatically inserts free statements to deallocate individual objects. This transformation is enabled by an inter-procedural, context-sensitive dataflow analysis that tracks the state of one object instance at a time, from the point where it is allocated, and up to the point where the object instance becomes unreachable and can be freed.For the SPECjvm98 benchmarks, free-instrumented programs generated by our compiler and executed in a virtual machine with explicit memory deallocation reclaim, on average, more than 50%of the total memory allocated by the program, and have a low run-time overhead of 1%. For several benchmarks, the analysis can free more than 85% of the total memory.
Statistical Models and Patient Predictors of Readmission for Heart Failure<subtitle>A Systematic Review</subtitle> (2008)

Our systematic review identified no model designed to compare hospital rates of readmission, while models designed to predict patients' readmission risk used heterogeneous approaches and found substantial inconsistencies regarding which patient characteristics were predictive. Clinically, patient risk stratification is challenging. From a policy perspective, a validated risk-standardized statistical model to accurately profile hospitals using readmission rates is unavailable in the published English-language literature to date.
Humoral and cellular immune responses of nonhuman primates to long-term repeated lung exposure to Ad2/CFTR-2. (1996)

To evaluate the host immune response to long-term repeat administration of adenovirus vector, rhesus monkeys were treated at intervals of approximately 3 weeks with up to 18 instillations of Ad2/CFTR-2, a second generation vector encoding the cystic fibrosis transmembrane conductance regulator (CFTR). All monkeys instilled with Ad2/CFTR-2 developed a significant humoral immune response against adenovirus but not CFTR. Antibodies with virus neutralizing activity were detected in the serum and bronchoalveolar lavage (BAL) of all vector-treated monkeys and included both IgG and secretory IgA. Virus-specific T cells capable of proliferating in response to stimulation with adenovirus antigen were detected in all vector-treated monkeys. No CFTR-specific proliferation of peripheral blood lymphocytes was detected. An increase in the proportion of CD8+ T cells was noted in the BAL of virus-treated monkeys but cells from the BAL displayed little or no cytolytic activity against infected autologous fibroblasts when tested under a variety of culture conditions. However, MHC-restricted cytolytic activity was detected in the tracheobronchial lymph nodes and spleen of one of three virus-treated monkeys tested. MHC-unrestricted killing of infected fibroblasts was also observed with spleen cells from all animals tested. From these results, it appears that both the humoral and cell-mediated arms of the immune response were stimulated by repeated administration of high doses of Ad2/CFTR-2 suggesting that effective, long-term adenovirus gene therapy may require modification of the vector or treatment of the host to allow the virus to evade host immune defenses.
Human and mouse introns are linked to the same processes and functions through each genome's most frequent non-conserved motifs (2008)

We identified the most frequent, variable-length DNA sequence motifs in the human and mouse genomes and sub-selected those with multiple recurrences in the intergenic and intronic regions and at least one additional exonic instance in the corresponding genome. We discovered that these motifs have virtually no overlap with intronic sequences that are conserved between human and mouse, and thus are genome-specific. Moreover, we found that these motifs span a substantial fraction of previously uncharacterized human and mouse intronic space. Surprisingly, we found that these genome-specific motifs are over-represented in the introns of genes belonging to the same biological processes and molecular functions in both the human and mouse genomes even though the underlying sequences are not conserved between the two genomes. In fact, the processes and functions that are linked to these genome-specific sequence-motifs are distinct from the processes and functions which are associated with intronic regions that are conserved between human and mouse. The findings show that intronic regions from different genomes are linked to the same processes and functions in the absence of underlying sequence conservation. We highlight the ramifications of this observation with a concrete example that involves the microsatellite instability gene MLH1.
블로그 동기와 이용자 규모에 대한 인식이 블로그 운영과 지속의사에 미치는 영향: 상호작용적 매체 이용자로서의 블로거 연구 (2011)

이 연구는 주로 블로그를 보는 이용자들의 동기와 이용행위에 집중했던 기존 연구들과 달리 블로그를 개설하고 운영하는 블로거의 상호작용적 동기와 행위에 주목했다. 특히 이용자들끼리 수평적 상호작용을 가능하게 하는 연결성에 주목하여 상호 작용하고 있는 상대, 즉 블로거가 가진 오디언스의 규모에 대한 인식을 주요 변수로 삼아 블로그 운영을 설명하고자 했다. 블로그 운영이 동기는 물론 블로그를 방문할 것으로 예상되는 이용자 규모에 대한 인식에 의해 영향을 받는다고 보고, 이들을 독립변수로 삼아 블로그 운영과 블로그 지속의사에 미치는 영향을 검토했다. 인터넷 패널을 대상으로 한 서베이 결과, 블로그 이용자 규모에 대한 인식은 블로거의 블로그 게시글 생산량과 블로그 운영 지속의사에 정적인 영향을 미치는 것으로 나타났다. 또한 블로그 운영 동기에 있어서 지신을 지향하는 자기기록적 동기와 커뮤니케이션 대상자인 타인을 지향하는 관계지향적 동기가 모두 블로그 운영 행위를 일정 부분 설명할 수 있음을 확인했다. 특히 자기기록적 동기와 관계지향적 동기는 블로그 게시글의 분량과 블로그 운영상의 노력 등에 차별적 방식으로 영향을 미치는 것으로 밝혀졌다.
Semantic-event based analysis and segmentation of wedding ceremony videos (2007)

Wedding is one of the most important ceremonies in our lives. It symbolizes the birth and creation of a new family. In this paper, we present a system for automatically segmenting a wedding ceremony video into a sequence of recognized wedding events, e.g., the couple's wedding kiss. Our goal is to develop an automatic tool for users to efficiently organize, search, and retrieve his/her treasured wedding memories. Furthermore, the event descriptions could benefit and complement the current research in semantic video understanding. Technically, three kinds of event features, i.e., the speech/music discriminator, flashlight detector, and bride indicator, are exploited to build statistical models for each wedding event. Events are then recognized by a hidden Markov model, which takes into account both the fitness of observed features and the temporal rationality of event ordering to improve the segmentation accuracy. We conducted experiments on a rich set of wedding videos, and the results demonstrate the effectiveness of our approach.
Multipactor testing and emerging qualification protocols (2016)

Interest on high RF power breakdown phenomena has been growing in recent years. Microwave vacuum devices are being used in space and on many terrestrial applications, where undesired multipactor effects can degrade their performance and features. Therefore, multipactor testing is advancing in several areas, and particularly in order to cover the gap between the classical single carrier scenarios to real world environment. Multicarrier and digital modulations also represent a challenge from the technical and regulatory point of view. This work presents the most recent advances on the multipactor testing, and describes a state of the art multipactor test bed used for navigation payload testing.
The Relationship Between Dry Eye Symptoms and Lipid Layer Thickness (2009)

(1) The data indicate that approximately 3 of 4 patients reporting severe symptoms have relatively thin lipid layers of 60 nm or less, whereas approximately 3 of 4 patients without symptoms have relatively thick lipid layers of 75 nm or more. Thus, the presence of dry eye symptoms significantly increases the likelihood of a relatively thin lipid layer. LLT seems to correlate better to symptoms, especially severe symptoms, than other reported correlations with objective clinical tests for dry eye disease. (2) Interferometry has the potential to be a practical and useful addition to clinical practice.
Standardization and Detailed Characterization of the Syngeneic Fischer/F98 Glioma Model (2007)

The standardized model described in this study behaves in a predictable and reproducible fashion, and could be considered for future pre-clinical studies. It adequately mimics the behavior of human malignant astrocytomas.
Characterization and chromosome location of the mouse link protein gene <i>(Crtl1)</i> (1999)

Link protein (LP) plays an essential role in endochondral bone formation by stabilizing the supramolecular assemblies of aggrecan and hyaluronan. We have isolated and characterized the mouse link protein gene (Crtl1). It is longer than 40 kb and transcribed from two alternative promoters, leading to heterogenous mRNAs between 5.3 and 1.3 kb in size. Apart from the coding sequence, the 5' flanking region is also highly conserved in mammals. Immunostaining revealed high levels of LP expression in the cartilaginous primordia of skeletal elements and low levels in other tissues. Using single-strand conformation polymorphism analysis, Crtl1 was assigned to mouse chromosome 13, tightly linked to Dhfr.
TRRespass: Exploiting the Many Sides of Target Row Refresh (2020)

After a plethora of high-profile RowHammer attacks, CPU and DRAM vendors scrambled to deliver what was meant to be the definitive hardware solution against the RowHammer problem: Target Row Refresh (TRR). A common belief among practitioners is that, for the latest generation of DDR4 systems that are protected by TRR, RowHammer is no longer an issue in practice. However, in reality, very little is known about TRR. How does TRR exactly prevent RowHammer? Which parts of a system are responsible for operating the TRR mechanism? Does TRR completely solve the RowHammer problem or does it have weaknesses? In this paper, we demystify the inner workings of TRR and debunk its security guarantees. We show that what is advertised as a single mitigation mechanism is actually a series of different solutions coalesced under the umbrella term Target Row Refresh. We inspect and disclose, via a deep analysis, different existing TRR solutions and demonstrate that modern implementations operate entirely inside DRAM chips. Despite the difficulties of analyzing in-DRAM mitigations, we describe novel techniques for gaining insights into the operation of these mitigation mechanisms. These insights allow us to build TRRespass, a scalable black-box RowHammer fuzzer that we evaluate on 42 recent DDR4 modules. TRRespass shows that even the latest generation DDR4 chips with in-DRAM TRR, immune to all known RowHammer attacks, are often still vulnerable to new TRR-aware variants of RowHammer that we develop. In particular, TRRespass finds that, on present-day DDR4 modules, RowHammer is still possible when many aggressor rows are used (as many as 19 in some cases), with a method we generally refer to as Many-sided RowHammer. Overall, our analysis shows that 13 out of the 42 modules from all three major DRAM vendors (i.e., Samsung, Micron, and Hynix) are vulnerable to our TRR-aware RowHammer access patterns, and thus one can still mount existing state-of-the-art system-level RowHammer attacks. In addition to DDR4, we also experiment with LPDDR4(X) <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sup> chips and show that they are susceptible to RowHammer bit flips too. Our results provide concrete evidence that the pursuit of better RowHammer mitigations must continue.
Final design of an air core, compulsator driven, 60 caliber railgun system (1991)

The manufacturing phase of a laboratory-based small-caliber electromagnetic (EM) launcher and compulsator power supply is discussed. The objective of the 29-month program is to develop a compact, lightweight test bed capable of accelerating 32 g masses to 2 km/s at a rate of 10 Hz. Both the power supply and launcher feature significant component design advances which will allow the system to operate at considerably higher energy and power densities than previously demonstrated. The 750 kg compulsator will generate 2.2 kV and the silicon-controlled rectifier (SCR) switch will commutate 386 kA pulses into the 1.6-m long, 0.60 caliber augmented solid armature railgun. The final design and predicted operating characteristics of the compulsator system are described. Overall system performance parameters are reported, including results from the optimization code used to aid in the design of the compulsator system. A system design overview is presented, with emphasis on new materials and state-of-the-art machine components to be used for the first time in a compulsator.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Dasatinib reverses Cancer-associated Fibroblasts (CAFs) from primary Lung Carcinomas to a Phenotype comparable to that of normal Fibroblasts (2010)

Cancer associated fibroblasts (CAFs) play a critical role for growth, invasion, and metastasis of cancer. Therefore, targeting CAFs with small molecule inhibitors may be an attractive anti-tumor strategy. The current study aims to identify small molecule kinase inhibitors affecting CAF's growth and to characterize the biological effects of active compounds on primary CAFs from lung cancer. We screened two individual CAF strains for their sensitivity to a panel of 160 kinase inhibitors. Five kinase inhibitors were identified inhibiting more than 50% of the growth of both cell lines. Three of them were inhibitors of PDGFR at nanomolar concentrations. Therefore, we further tested the FDA approved PDGFR inhibitors Dasatinib, Nilotinib, Sorafenib, and Imatinib. All 37 CAF strains investigated were highly sensitive to Dasatinib at clinically relevant concentrations. Imatinib was slightly less effective, whereas the inhibitory effects of Nilotinib and Sorafenib were significantly less pronounced.We investigated the effect of Dasatinib on the CAF transcriptome by microarray analysis of 9 individual CAF strains. 492 genes were identified whose expression was changed at least twofold. 104 of these encoded cell cycle related proteins with 97 of them being downregulated by Dasatinib. The majority of regulated genes, however, were of diverse biological functions not directly related to proliferation. We compared this Dasatinib expression signature to previously described differential signatures of normal tissue associated fibroblasts (NAFs) and CAFs and to a signature of fibroblast serum response. There was a significant overlap between genes regulated by Dasatinib and serum repression genes. More importantly, of the 313 genes downregulated by Dasatinib 64 were also reduced in NAFs compared to CAFs. Furthermore, 26 of 179 genes identified as upregulated by Dasatinib were also found to be elevated in NAFs compared to CAFs. These data demonstrate that Dasatinib partially reverses the phenotype of CAFs to a normal fibroblast like phenotype. This is further supported by the finding that incubation of tumor cells with conditioned medium from CAFs pre-incubated with Dasatinib significantly reduced tumor cell proliferation, suggesting that Dasatinib partially reverses the CAF mediated tumor promoting effect. Therefore, targeting CAFs with Dasatinib represents a promising therapeutic principle.
Efficient Dye-Sensitized Solar Cells with an Organic Photosensitizer Featuring Orderly Conjugated Ethylenedioxythiophene and Dithienosilole Blocks (2010)

In view of the limited ruthenium resource, metal-free organic dyes may play a prominent role in the coming large-scale application of cost-effective dye-sensitized solar cells, if their efficiency and stability can be considerably improved. In this paper we utilized a binary π-conjugated spacer of ethylenedioxythiophene and dithienosilole to construct a high molar absorption coefficient push−pull dye, characteristic of an intramolecular charge-transfer band peaking at 584 nm measured in chloroform. In comparison with the standard ruthenium sensitizer Z907, this metal-free chromophore C219 endowed a nanocrystalline titania film with an evident light-harvesting enhancement, leading to an unprecedented 10.0−10.3% efficiency at the AM1.5G conditions for dye-sensitized solar cells with nonruthenium dyestuffs, although a highly volatile electrolyte was used. Transient absorption measurements have revealed that even if the kinetics of back-electron transfer and dye regeneration are considerably different for Z907 and C219, the branching ratios of these two charge-transfer channels are over 35 for both dyes, ensuring a high yield of net charge separation at the titania/dye/electrolyte interface. A solvent-free ionic liquid cell with C219 as the sensitizer exhibited an impressive efficiency of 8.9% under a low light intensity of 14.39 mW cm−2, making it very favorable for the indoor application of flexible dye-sensitized solar cells.
A hybrid probe-tip calibration for multiport vector network analyzers (2006)

This paper details the first commercial implementation [1] of a hybrid multiport vector network analyzer (VNA) calibration method suited to a probing environment. The new calibration method implements the enhanced Line-Reflect-Reflect-Match with automatic determination of load inductance [2]-[5] for a number of straight thru paths to fully determine all directivity, reflection tracking, and source and load match terms as well as the associated transmission tracking terms. The remaining transmission tracking terms are found from the use of an unknown but reciprocal thru structure using a process similar to that of the SOLR [6]-[7] calibration algorithm. Combining the LRRM and SOLR algorithms creates a robust, hybrid calibration method that is insensitive to the normal variation in one-port standard behavior associated with normal probe-placement variability [8]-[9]. The hybrid calibration is also insensitive to the inherently non-ideal thru behavior of coplanar waveguide bends or loop-back structures [10].
Prevalence of HFE genotypes, C282Y and H63D, in patients with hematologic disorders. (2002)

Our results do not show any significant association between HFE gene mutations and hematologic malignancies. The divergent frequencies observed for the C282Y mutation in patients with AML and ET highlight the need for larger population studies of HFE mutations in patients with hematologic diseases.
In Vitro Evaluation of the Impact of the Probiotic E. coli Nissle 1917 on Campylobacter jejuni’s Invasion and Intracellular Survival in Human Colonic Cells (2017)

<i>Campylobacter jejuni</i> is a leading cause of bacterial food poisoning in humans. Due to the rise in antibiotic-resistant <i>Campylobacter</i>, there exists a need to develop antibiotic-independent interventions to control infections in humans. Here, we evaluated the impact of <i>Escherichia coli</i> Nissle 1917 (EcN), a probiotic strain, on <i>C. jejuni's</i> invasion and intracellular survival in polarized human colonic cells (HT-29). To further understand how EcN mediates its impact, the expression of 84 genes associated with tight junctions and cell adhesion was profiled in HT-29 cells after treatment with EcN and challenge with <i>C. jejuni</i>. The pre-treatment of polarized HT-29 cells with EcN for 4 h showed a significant effect on <i>C. jejuni</i>'s invasion (∼2 log reduction) of the colonic cells. Furthermore, no intracellular <i>C. jejuni</i> were recovered from EcN pre-treated HT-29 cells at 24 h post-infection. Other probiotic strains tested had no significant impact on <i>C. jejuni</i> invasion and intracellular survival. <i>C. jejuni</i> decreased the expression of genes associated with epithelial cells permeability and barrier function in untreated HT-29 cells. However, EcN positively affected the expression of genes that are involved in enhanced intestinal barrier function, decreased cell permeability, and increased tight junction integrity. The results suggest that EcN impedes <i>C. jejuni</i> invasion and subsequent intracellular survival by affecting HT-29 cells barrier function and tight junction integrity. We conclude that EcN might be a viable alternative for controlling <i>C. jejuni</i> infections.
Extended Infusion of Dexmedetomidine to an Infant at Sixty Times the Intended Rate (2010)

Dexmedetomidine is an α2 adrenergic agonist which has recently been approved in the United States for procedural sedation in adults. This report describes an infant who inadvertently received an intravenous infusion of dexmedetomidine at a rate which was 60 times greater than intended. We describe the hemodynamic, respiratory, and sedative effects of this overdose.
Bulk-Si with poly bump process scheme for MEMS sensors (2012)

A MEMS process scheme designed for multi- sensors is presented. This new process scheme includes a poly bump not only provides stiction prevention and gap control function, and also electrical connection between MEMS structure and routing lines. Another advantage for this scheme is a better vacuum level because all material can be high temperature annealed before final encapsulation. This study also demonstrated some MEMS devices using this new scheme, including resonators, accelerometers and magnetometers.
High-resolution alpha-particle spectrometry using 4H silicon carbide semiconductor detectors (2006)

SiC detectors with active volume dimensions sufficient to stop alpha particles have been manufactured and tested. A linear energy response and excellent energy resolution have been obtained for various alpha emitters in the 3.18-MeV to 8.38-MeV energy range. Evaluation of the contributing factors to the SiC detector energy resolution indicates that the measured values for the full width at half maximum (FWHM) are limited by energy straggling of the alpha particles as they pass through the metallic contact layers that comprise the entrance window to the detector. Even with this component included in the measured FWHM, the measured values are comparable to those achievable with silicon alpha spectrometers. The possibility that the energy resolution that can be achieved with SiC may surpass that of silicon can not be excluded. SiC alpha spectrometers are expected to be useful in many nuclear applications where the ability to operate in high-temperature and high-radiation environments is required. Such applications include monitoring of alpha particles, neutrons, and low-energy gamma rays and X-rays in actinide waste-tank environments as well as neutron and gamma-ray monitoring of spent nuclear fuel assemblies.