gebhart/patrepeval huggingface dataset:
Mechanical and Electrical Properties of Nonwoven Coated with CNFs/PVDF-HFP Composite (2011)

In this study, the process of preparation nonwoven with coated carbon nano fibers (CNFs) /poly(vinylidene fluoride-co-hexafluoropropylene) (PVDF-HFP) composite solution is described. The various contents of CNFs/PVDF-HFP composite coated nonwoven were prepared and characterized by morphological, mechanical, and electrical methods. Nonwovens are coated with CNFs/PVDF-HFP composite solution and decreased the pick up ratio with increasing CNFs contents in range from 0% to 16%. In the results of SEM images, it was clear that the CNFs were evenly distributed in coated nonwoven by SEM images, the existence of CNFs in coated nonwoven was confirmed regularly. The mechanical properties of various contents of CNFs/PVDF-HFP coated nonwoven were examined. The tensile linearity and compression linearity increased with increasing CNFs contents. The electrical properties of the CNFs/PVDF-HFP coated nonwoven increased with increasing CNFs contents.
R-Opus: A Composite Framework for Application Performability and QoS in Shared Resource Pools (2006)

We consider shared resource pool management taking into account per-application quality of service (QoS) requirements and server failures. Application QoS requirements are defined by complementary specifications for acceptable and time-limited degraded performance. Furthermore, a requirement specification is provided for both the normal case and for the case where an application server fails in the pool. Independently, the resource pool operator provides a resource access QoS commitment for two classes of service (CoS). These govern statistical multiplexing within the pool. A QoS translation automatically maps application demands onto the resource pool's CoS to best enable sharing. A workload placement service consolidates applications to a small number of servers while satisfying application QoS requirements. The service reports whether a spare server is needed or how applications affected by a single failure can operate according to failure QoS constraints using remaining servers until the failure can be repaired. A case study demonstrates the approach
Mechanistic Insights into the Enhanced Activity and Stability of Agglomerated Cu Nanocrystals for the Electrochemical Reduction of Carbon Dioxide to <i>n</i>-Propanol (2015)

The reduction of carbon dioxide (CO2) to n-propanol (CH3CH2CH2OH) using renewable electricity is a potentially sustainable route to the production of this valuable engine fuel. In this study, we report that agglomerates of ∼15 nm sized copper nanocrystals exhibited unprecedented catalytic activity for this electrochemical reaction in aqueous 0.1 M KHCO3. The onset potential for the formation of n-propanol was 200-300 mV more positive than for an electropolished Cu surface or Cu(0) nanoparticles. At -0.95 V (vs RHE), n-propanol was formed on the Cu nanocrystals with a high current density (jn-propanol) of -1.74 mA/cm(2), which is ∼25× larger than that found on Cu(0) nanoparticles at the same applied potential. The Cu nanocrystals were also catalytically stable for at least 6 h, and only 14% deactivation was observed after 12 h of CO2 reduction. Mechanistic studies suggest that n-propanol could be formed through the C-C coupling of carbon monoxide and ethylene precursors. The enhanced activity of the Cu nanocrystals toward n-propanol formation was correlated to their surface population of defect sites.
[A survey of radical surgery without neoadjuvant therapy for patients with stage B and C prostatic carcinoma]. (2001)

There has been much controversy regarding radical surgery for both localized and locally extensive carcinoma of the prostate. We analyzed the outcome of radical prostatectomy and the preoperative evaluation in order to assess the indication of radical prostatectomy. Fifty-six patients with clinical stage B or C prostate cancer were treated by radical prostatectomy without neoadjuvant therapy. Endocrine therapy was added to the non-curative cases postoperatively. Preoperative evaluation was compared with pathological results and survival, and furthermore the usefulness of the preoperative PSA and PSA half-life were investigated. The mean follow-up period was 44.5 months. The accuracy of the grade and the clinical stage were 58.9% and 23.2%, respectively. Organ-confined disease was seen in patients with an initial PSA level less than 30 ng/ml. Postoperative PSA half-life is significantly prolonged in cases with poorly differentiated adenocarcinoma or lymph node involvement and may be a predictor of PSA failure. The cause-specific 5-year survival rates were 92.7% on the whole, 92.9% for well differentiated, 96.7% for moderately differentiated, 85.7% for poorly differentiated, 100% for stage B1, 95.0% for stage B2 and 86.8% for stage C. These results indicated that patients with an initial PSA level of less than 30 ng/ml will benefit from radical prostatectomy.
Galeal flap: clinical application in periorbital and orbital reconstruction. (1996)

We report the use of a galea flap in the reconstruction of the orbit and the periorbital in region three representative cases. Two patients, who had communication between the orbit, paranasal sinuses, and cranium following orbital and periorbital tumor resection, required a physical barrier to partition these compartments and an immunological barrier to prevent infection. A third patient, who had a contracted socket and had been on systemic steroids chronically, required a tissue with intrinsic blood supply to sustain an implant and promote healing. The outcome in all three patients was gratifying. The surgical anatomy is reviewed, the surgical technique detailed, and potential applications and complications discussed.
Isolation and Expression Analysis of Cu/Zn-Superoxide Dismutase Genes from Three<i>Caragana</i>Species (2014)

Caragana is a native desert shrub with high forage values and stress tolerance, as well as sand fixing capabilities. Some Caragana species, including C. korshinskii, C. microphylla, and C. intermedia, are com monly used for vegetation restoration programs in the Loess Plateau region of northwestern China and are known to have ecological benefits and high commercial value. In this study, full length sequences of Cu/Zn SOD genes were isolated from three Caragana species using degenerate polymerase chain reaction (PCR) and rapid amplification of cDNA ends (RACE) techniques, and their expression under drought stress conditions were investigated. The cloned SOD cDNAs contained a predicted open reading frame (ORF) of 459 bp encoding a polypeptide of 152 amino acids with a theoretical molecular weight of 15.2 kD. Cu/Zn SOD cDNA of C. korshinskii and C. intermedia shared 100% sequence identity, implying a close relationship. A 24 bp specific sequence was found in the 3 UTR region of C. microphylla Cu/Zn SOD cDNA, and reverse tran scription RT PCR and genomic PCR confirmed the feasibility of the 24 bp sequence as a DNA marker for rapid variety identification of C. microphylla. RT PCR revealed that the expression of the Caragana Cu/Zn SOD genes was induced by PEG simulated drought stress and ABA. The three Caragana Cu/Zn SOD genes showed similar expression patterns, and no significant differences in transcriptional level were observed among the three genes. These results increase our understanding of the molecular mechanism of drought tol erance and can be used to improve vegetation restoration programs of Caragana plants.
Horizontal-based orchestration for multi-domain SFC in SDN/NFV-enabled satellite/terrestrial networks (2018)

It's promising to use Software-Defined Networking (SDN) and Network Functions Virtualization (NFV) to integrate satellite and terrestrial networks. To construct network service function chains in such a multi-domain environment, we propose a horizontal-based Multi-domain Service Function Chaining (Md-SFC) orchestration framework. In this framework, multi-domain orchestrators can coordinate with each other to guarantee the end-to-end service quality. Intra-domain orchestrators also coordinate SDN controllers and NFV management components to implement intra-domain service function chains. Based on this, we further propose a heuristic SFC mapping algorithm with a cooperative inter-domain path calculation method to map service function chains to infrastructures. In this method, master multi-domain orchestrator and intra-domain orchestrators coordinate to select proper inter-domain links. We compare the cooperative method with a naive uncooperative way that domains' topology information is provided to the master multi-domain orchestrator and it calculates the shortest inter-domain path between intra-domain service function chains directly. Simulation results demonstrate that our solution is feasible. It is able to construct end-to-end performance guaranteed service function chain by horizontal-based cooperation. The cooperative inter-domain path calculation method decreases the mapping load for the master orchestrator and gets the same end-to-end performance.
Screening of Allium Tester Lines in Vitro with Pyrenochaeta terrestris Filtrates (1992)

Callus cultures were established from intraspecific lines of Allium cepa L., interspecific F 1 progeny of A. cepa crossed to A. fistulosum L. and to A. galanthum L., advanced generations of A. fistulosum x A. cepa backcrossed to A. cepa, and lines of A. fistulosum and A. galanthum. These genotypes had been identified as susceptible, resistant, or partially resistant tester lines based on prior seedling and field nursery screenings using the pink-root pathogen Pyrenochaeta terrestris (Hansen) Gorenz, Walker and Larson. Tester line calli were challenged in vitro with culture filtrates of the fungal pathogen and were assessed by visible damage ratings expressed as the percentage of pigmentation in response to the filtrate. The degrees of callus sensitivity to the filtrate observed in vitro corresponded well with the in vivo tester line classifications. These results eliminated the possible confounding influence of using various species of Allium for in vitro screening. Our results indicated the suitability of the in vitro screening approach for the possible identification of useful segregants or somaclonal variants possessing pink-root resistance. However, in vivo pathogenicity may involve mechanisms in addition to sensitivity to the putative toxins present in the filtrate.
Prevention and treatment of experimental herpes simplex virus encephalitis with human immune serum globulin (1987)

Pooled human immunoglobulin suitable for intravenous administration (IGIV) was evaluated in the prophylaxis and treatment of herpes simplex virus (HSV) type 1 encephalitis in a murine model. Four-week-old BALB/c mice received a single intraperitoneal injection of IGIV or saline 24 h before or up to 24 h after intranasal infection with 10(4.6) PFU of HSV type 1. Treatment with IGIV was protective against death, and the protective effects were dose and time dependent. Treatment with IGIV blocked the production of HSV antibody by infected mice and reduced the number of trigeminal ganglia containing latent virus. Removal of neutralizing antibody from the IGIV pool did not eliminate the protective effect, whereas F(ab)2 fragments of IGIV, which had virus-neutralizing activity that was identical to that of native IGIV, conferred no protection against death. Pooled human IGIV was effective for the prevention and treatment of HSV encephalitis in mice. Antibody-mediated protection required the Fc portion of the immunoglobulin molecule but did not require the direct neutralization of virus.
Dye-Sensitized Solar Cells with a High Absorptivity Ruthenium Sensitizer Featuring a 2-(Hexylthio)thiophene Conjugated Bipyridine (2009)

We conjugated 2-(hexylthio)thiophene with bipyridine to construct a new heteroleptic polypyridyl ruthenium sensitizer exhibiting a charge-transfer band at 550 nm with a molar extinction coefficient of 18.7 × 103 M−1 cm−1. In contrast to its analogues Z907 and C101, a mesoporous titania film stained with this new sensitizer featured a short light absorption length, allowing for the use of a thin photoactive layer for efficient light-harvesting and conversion of solar energy to electricity. With a preliminary testing, we have reached 11.4% overall power conversion efficiency measured at the air mass 1.5 global conditions. Transient photoelectrical decays and electrical impedance spectra were analyzed to picture the intrinsic physics of temperature-dependent photovoltage and photocurrent.
Current summary of clinical studies on anti-TSLP antibody, Tezepelumab, in asthma (2022)

Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine that plays a vital role in the induction of type 2 inflammation via both innate and acquired immune cascades. Tezepelumab, a human IgG2 monoclonal antibody that inhibits the binding of TSLP to the TSLP receptor, is the latest biologic for asthma. To evaluate the efficacy and mechanism of tezepelumab in asthma, the PATHWAY, NAVIGATOR, NOZOMI, UPSTREAM, CASCADE, SOURCE, and DESTINATION studies have been conducted. These results suggested that tezepelumab is a broad-target biologic, which is expected to be effective in patients with poorly controlled moderate to severe asthma regardless of the phenotype, although its efficacy in oral corticosteroids-dependent asthma, biological mechanism in non-type 2 phenotype, and long-term safety remain unknown. In this review, we summarize the results of clinical trials of tezepelumab in asthma and discuss the differences between tezepelumab and other biologics.
Molecular cloning and characterization of a cDNA for a novel phorbol-12-myristate-13-acetate-responsive gene that is highly expressed in an adult T-cell leukemia cell line (1990)

To identify gene products that might be involved in leukemogenesis of adult T-cell leukemia (ATL), we constructed a cDNA library from an ATL tumor cell line named IKD. By differential plaque hybridization using [32P]cDNAs of poly(A)+ RNA from IKD cells and a human T-lymphotropic virus type I-infected T-cell line (C91/PL) as probes and RNA blot analysis, we obtained a single cDNA clone of a gene that is highly expressed in IKD cells. Expression of this gene was also detected in fresh peripheral blood mononuclear cells of several ATL patients but not in those of healthy donors. Sequence analysis showed that the cDNA was that of a previously undescribed gene. On structural analysis of the cDNA (1,897 base pairs), a short open reading frame encoding a polypeptide of 54 amino acid residues was found. Exposure of human peripheral blood mononuclear cells, a T-cell lymphoma cell line (Jurkat), and quiescent human embryonic lung cells to phorbol-12-myristate-13-acetate resulted in rapid, transient expression of 2.0-kilobase mRNA of this gene. This induction of the gene was not inhibited by an inhibitor of protein synthesis, cycloheximide. From these findings, we suggest that this gene, named APR, is a member of the cellular immediate-early-response genes.
Texton Noise (2017)

Abstract Designing realistic noise patterns from scratch is hard. To solve this problem, recent contributions have proposed involved spectral analysis algorithms that enable procedural noise models to faithfully reproduce some class of textures. The aim of this paper is to propose the simplest and most efficient noise model that allows for the reproduction of any Gaussian texture. Texton noise is a simple sparse convolution noise that sums randomly scattered copies of a small bilinear texture called texton . We introduce an automatic algorithm to compute the texton associated with an input texture image that concentrates the input frequency content into the desired texton support. One of the main features of texton noise is that its evaluation only consists to sum 30 texture fetches on average. Consequently, texton noise generates Gaussian textures with an unprecedented evaluation speed for noise by example. A second main feature of texton noise is that it allows for high‐quality on‐the‐fly anisotropic filtering by simply invoking existing GPU hardware solutions for texture fetches. In addition, we demonstrate that texton noise can be applied on any surface using parameterization‐free surface noise and that it allows for noise mixing.
Efficient Between-Satellite Single-Difference Precise Point Positioning Model (2013)

This paper describes a new model for precise point positioning (PPP), which overcomes the drawbacks of existing PPP models. This model is based on between-satellite single-difference (BSSD), which cancels out the receiver clock error, receiver initial phase bias, and receiver hardware delay. The decoupled clock (DC) corrections, which were provided by Natural Resources Canada (NRCan), were applied to account for code and carrier-phase satellite clock corrections, satellite hardware delay, and satellite initial phase bias. The results from three PPP models (namely, undifferenced-DC, BSSD, and BSSD-DC) were compared with the traditional (i.e., undifferenced) PPP solution. It is shown that the proposed BSSD models improves the PPP convergence time by up to 50% and improves the solution precision by more than 60% in comparison with the traditional PPP model.
Wireless Surgical Tools for Mechanical Measurements during Scoliosis Surgery (2005)

Comprehensively understanding the mechanics of loads applied by orthopaedic surgeons and distributed to the spine during scoliosis corrective surgery may improve surgical outcome and patient safety. Instruments to measure forces applied by orthopaedic surgeons have been reported. This paper presents instrumented hooks and screws with a real time wireless data acquisition system to measure loads and moments distributed to the spine during scoliosis surgery. From laboratory tests, the maximum error of posterior/anterior forces and moments were 2-3% of the maximum loads during surgery. This study improves the understanding of mechanics during surgical correction.
A task remapping technique for reliable multi-core embedded systems (2010)

With the continuous scaling of semiconductor technology, the life-time of circuit is decreasing so that processor failure becomes an important issue in MPSoC design. A software solution to tolerate run-time processor failure is to migrate tasks from the failed processors to the live processors when failure occurs. Previous works on run-time task migration usually aim to minimize the migration overhead with or without a given latency constraint. For streaming applications, however, it is more important to minimize the throughput degradation than the migration overhead or the latency. Hence, we propose a task remapping technique to minimize the throughput degradation assuming that the migration overhead can be amortized safely. The target multi-core system assumed in this paper consists of processor pools and each pool consists of homogeneous processors. The proposed technique is based on an intensive compile-time analysis for all possible failure scenarios. It involves the following steps; 1) Determine the static mapping of tasks onto the live processors, aiming to minimize the throughput degradation: 2) Find an optimal processor-to-processor mapping to minimize the task migration overhead: and 3) Store the resultant task remapping information that includes task mapping and processor-to-processor mapping results. Since the task remapping information is pre-computed at compile-time for all possible failure scenarios, it should be efficiently represented and stored. At run-time, we simply remap the tasks following the compile-time decision. We examine the scalability of the proposed technique on both space and run-time overhead for compile-time analysis varying the number of failed processors. Through intensive experiments, we show that the proposed technique outperforms the previous works with respect to application throughput.
[Diagnosis and surgical treatment of anomalies of the vertebral arteries]. (1990)

Different types of anomalies of the vertebral arteries are described on the basis of experience in 611 operations on these vessels. The authors emphasize the clinical importance of clamping and compression, as well as anomalous origin and entry of the vertebral arteries into the bone canal. The authors' experience allows them to believe that congenital anomalies and pathological tortousness of the carotid and vertebral arteries play an important role in the etiopathogenesis of cerebral circulatory disorders both in children and in adults.
The serum-inducible protein kinase Snk is a G1 phase polo-like kinase that is inhibited by the calcium- and integrin-binding protein CIB. (2003)

Identified as an immediate-early transcript, the serum-inducible kinase Snk bears sequence homology with the polo-like kinases. Endogenous Snk was detected in early G(1) in NIH 3T3 cells, and nascent Snk showed a half-life of about 15 min. The kinase activity of endogenous Snk was detected in G(1). Substitution of Thr-236 with a glutamate residue increased Snk kinase activity by about 10-fold, whereas substitution of Lys-108 abolished its kinase activity. Disrupting the polo-box did not significantly change Snk kinase activity. A GFP-C-Snk fusion protein showed polo-box-dependent localization to the microtubule organizing center, and ectopic expression of Snk in COS-7 cells induced changes in cell morphology, depending on Snk kinase activity and the polo-box. The capacity of Snk to induce morphological changes was inhibited by the calcium- and integrin-binding protein CIB. CIB co-immunoprecipitated with Snk and inhibited the kinase activity of Snk, suggesting that CIB is a negative regulator for Snk kinase activity.
Calcification in atherosclerosis. I. Human studies. (1986)

Early atherosclerotic lesions in human aortas less than five hours postmortem were studied by light microscopy (20 cases) and electron microscopy (10 cases), to determine the morphological and cytochemical character of calcium deposition in the lesions. Routine and multiple special stains by light microscopy demonstrated atherosclerotic (intimal) calcium to be deposited as fine grains, ring-shaped droplets or small needle-shaped crystals, and medial calcium as fine grains or ring-shaped droplets. The calcium deposits were frequently associated with the PAS-positive basal lamina surrounding smooth muscle cells. In the intimal lesions the calcium deposits were often associated with fine granular lipid, while this association was much less frequent in the media. Calcium in atherosclerotic intima was generally not closely associated with elastic fibers but in the media was often deposited along or near elastic fibers. By electron microscopy the atherosclerotic lesions were composed of many smooth muscle cells (with or without lipid droplets), newly formed elastic fibers, amorphous ground substance, a few collagen fibrils and many membrane-limited matrix vesicle-like structures, 100-700 nm diameter. Many similar vesicles were present between the elastic laminae of the media. With the potassium pyroantimonate technique for demonstrating calcium, reaction products were most concentrated within these matrix vesicles but were also present in mitochondria of smooth muscle cells, within extracellular mitochondria-like structures, in pericellular basal lamina-like material and loosely dispersed in the interstitial ground substance. All elastic fibers were negative for calcium by this technique. The membrane of the matrix vesicle-like structures were cytochemically positive for alkaline phosphatase and adenosine triphosphatase. These studies suggest that calcification in human atherosclerosis and media is related to smooth muscle cell degeneration and that the major initial loci for calcium deposition are matrix vesicles from degraded cells, comparable to osteogenic calcification of cartilage.