gebhart/patrepeval huggingface dataset:
Frogs use a viscoelastic tongue and non-Newtonian saliva to catch prey (2017)

Frogs can capture insects, mice and even birds using only their tongue, with a speed and versatility unmatched in the world of synthetic materials. How can the frog tongue be so sticky? In this combined experimental and theoretical study, we perform a series of high-speed films, material tests on the tongue, and rheological tests of the frog saliva. We show that the tongue's unique stickiness results from a combination of a soft, viscoelastic tongue coupled with non-Newtonian saliva. The tongue acts like a car's shock absorber during insect capture, absorbing energy and so preventing separation from the insect. The shear-thinning saliva spreads over the insect during impact, grips it firmly during tongue retraction, and slides off during swallowing. This combination of properties gives the tongue 50 times greater work of adhesion than known synthetic polymer materials such as the sticky-hand toy. These principles may inspire the design of reversible adhesives for high-speed application.
T-Cell Subsets and Expression of Integrins in Peripheral Blood of Patients with Migraine (1999)

Neurogenic inflammation is considered as an animal model of human migraine attacks. Using flow cytometry, we examined T-cell subsets and their integrin expression in the peripheral blood of 32 migraine patients in order to evaluate a possible inflammatory process in humans, as postulated in the migraine animal model. Our results show that migraine patients have a significant increased proportion of T-helper (47.4 +/- 6.3% vs 43.2 +/- 5.8%; p < 0.01) and T-helper memory cells (23.6 +/- 5.9 vs 20.3 +/- 6.5%; p < 0.01). Moreover, the 22 migraine patients without aura also exhibited an increase of LFA-1 expression of T-helper cells (34.7 +/- 11.5%) compared to the 35 controls (27.5 +/- 12.0%; p < 0.01). These preliminary results support the hypothesis that immunological mechanisms (such as an enhanced lymphocyte endothelium interaction) could be part of the migraine pathophysiology in humans.
Efficient Coding Tree Unit (CTU) Decision Method for Scalable High-Efficiency Video Coding (SHVC) Encoder (2016)

High-efficiency video coding (HEVC or H.265) is the latest video compression standard developed by the joint collaborative team on video coding (JCT-VC), finalized in 2013. HEVC can achieve an average bit rate decrease of 50% in comparison with H.264/AVC while still maintaining video quality. To upgrade the HEVC used in heterogeneous access networks, the JVT-VC has been approved scalable extension of HEVC (SHVC) in July 2014. The SHVC can achieve the highest coding efficiency but requires a very high computational complexity such that its real-time application is limited. To reduce the encoding complexity of SHVC, in this chapter, we employ the temporal-spatial and inter-layer correlations between base layer (BL) and enhancement layer (EL) to predict the best quadtree of coding tree unit (CTU) for quality SHVC. Due to exist a high correlation between layers, we utilize the coded information from the CTU quadtree in BL, including inter-layer intra/residual prediction and inter-layer motion parameter prediction, to predict the CTU quadtree in EL. Therefore, we develop an efficient CTU decision method by combing temporal-spatial searching order algorithm (TSSOA) in BL and a fast inter-layer searching algorithm (FILSA) in EL to speed up the encoding process of SHVC. The simulation results show that the proposed efficient CTU decision method can achieve an average time improving ratio (TIR) about 52–78% and 47–69% for low delay (LD) and random access (RA) configurations, respectively. It is clear that the proposed method can efficiently reduce the computational complexity of SHVC encoder with negligible loss of coding efficiency with various types of video sequences.
Surface-enhanced Raman spectroscopy of platinum. 3. Enhanced light scattering of electrogenerated bromine and tribromide ions coadsorbed on a platinum electrode (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSurface-enhanced Raman spectroscopy of platinum. 3. Enhanced light scattering of electrogenerated bromine and tribromide ions coadsorbed on a platinum electrodeB. H. Loo and Y. G. LeeCite this: J. Phys. Chem. 1984, 88, 4, 706–709Publication Date (Print):February 1, 1984Publication History Published online1 May 2002Published inissue 1 February 1984https://pubs.acs.org/doi/10.1021/j150648a017https://doi.org/10.1021/j150648a017research-articleACS PublicationsRequest reuse permissionsArticle Views150Altmetric-Citations15LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Hyperexpression of biologically active human chorionic gonadotropin using the methylotropic yeast, Pichia pastoris (1999)

Human chorionic gonadotropin (hCG), a heterodimeric glycoprotein hormone, is composed of an alpha subunit noncovalently associated with the hormone-specific beta subunit. The objective of the present study was recombinant expression of properly folded, biologically active hCG and its subunits using an expression system that could be used for structure-function studies while providing adequate quantities of the hormone for immunocontraceptive studies. We report here expression of biologically active hCG and its subunits using a yeast expression system, Pichia pastoris. The recombinant hCGalpha and hCGbeta subunits were secreted into the medium and the levels of expression achieved at shake culture level were 24 and 2.7-3 mg/l secretory medium respectively. Co-expression of both subunits in the same cell resulted in secretion of heterodimeric hCG into the medium. The pichia-expressed hCG was immunologically similar to the native hormone, capable of binding to the LH receptors and stimulating a biological response in vitro. Surprisingly, the maximal response obtained was twice that obtained with the native hCG. The level of expression of hCG achieved was 12-16 mg/l secretory medium and is expected to increase several-fold in a fermentor. Thus the Pichia expression system is capable of hyperexpressing properly folded, biologically active hCG and is suitable for structure-function studies of the hormone.
INCREASED NITRIC OXIDE PRODUCTION IN HYPOTENSIVE HEMODIALYSIS PATIENTS (1996)

Lin, Shih-Hua; Lin, Yuh-Feng; Diang, Liang-Kuang; Yu, Fu-Chiu; Shieh, Shang-Der Author Information
Reelin Regulates the Development and Synaptogenesis of the Layer-Specific Entorhino-Hippocampal Connections (1999)

Here we examine the role of Reelin, an extracellular protein involved in neuronal migration, in the formation of hippocampal connections. Both at prenatal and postnatal stages, the general laminar and topographic distribution of entorhinal projections is preserved in the hippocampus of reeler mutant mice, in the absence of Reelin. However, developing and adult entorhinal afferents show severe alterations, including increased numbers of misrouted fibers and the formation of abnormal patches of termination from the medial and lateral entorhinal cortices. At perinatal stages, single entorhinal axons in reeler mice are grouped into thick bundles, and they have decreased axonal branching and decreased extension of axon collaterals. We also show that the number of entorhino-hippocampal synapses is lower in reeler mice than in control animals during development. Studies performed in mixed entorhino-hippocampal co-cultures combining slices from reeler and wild-type mice indicate that these abnormalities are caused by the lack of Reelin in the target hippocampus. These findings imply that Reelin fulfills a modulatory role during the formation of layer-specific and topographic connections in the hippocampus. They also suggest that Reelin promotes maturation of single fibers and synaptogenesis by entorhinal afferents.
ONE YEAR VERIFICATION OF WAVE PREDICTIONS BY DEEP LEARNING USING XCEPTION (2020)

Accurate and timely wave forecast is vital for port maintenance and management as well as general maritime safety. Modern numerical wind-wave modeling calculates the physical processes involved in wave generation, interaction, propagation, and dissipation, requiring large amounts of computational power to timely complete the required calculations. Convolutional Neural Networks (CNNs) have shown to improve wave prediction in viewpoints of lesser computational cost and processing speed. This study examines the application of Xception deep learning architecture for wave predictions along Japanese coasts of the Sea of Japan with input features of the Japan Meteorological Agency’s Grid Point Value Meso-Scale Model (GPV-MSM). In particular, this study aims to verify the forecast skill for a testing period of one year and to understand how wave forecasts by deep learning models can be improved and utilized.
Data-Driven Sparse Structure Selection for Deep Neural Networks (2017)

Deep convolutional neural networks have liberated its extraordinary power on various tasks. However, it is still very challenging to deploy state-of-the-art models into real-world applications due to their high computational complexity. How can we design a compact and effective network without massive experiments and expert knowledge? In this paper, we propose a simple and effective framework to learn and prune deep models in an end-to-end manner. In our framework, a new type of parameter -- scaling factor is first introduced to scale the outputs of specific structures, such as neurons, groups or residual blocks. Then we add sparsity regularizations on these factors, and solve this optimization problem by a modified stochastic Accelerated Proximal Gradient (APG) method. By forcing some of the factors to zero, we can safely remove the corresponding structures, thus prune the unimportant parts of a CNN. Comparing with other structure selection methods that may need thousands of trials or iterative fine-tuning, our method is trained fully end-to-end in one training pass without bells and whistles. We evaluate our method, Sparse Structure Selection with several state-of-the-art CNNs, and demonstrate very promising results with adaptive depth and width selection.
Separation and purification of six biosurfactant rhamnolipids by high-speed countercurrent chromatography utilizing novel solvent selection method (2015)

In this study, an original solvent selection method was developed for the separation of biosurfactant rhamnolipids from fermentation broth by high-speed countercurrent chromatography. For this method, calculations were based on solubility and functional group parameters that enabled the rapid selection of suitable solvent systems at no more than 10% of average time by traditional method. Based on selection results, a three-phase solvent system composed of n-hexane-methyl acetate-acetonitrile-water (2:2:2:5, v/v) was efficiently used for one-step separation of a mixture of six rhamnolipids. Thereby, RhaC10C10 (0.73 mg), RhaC10 (0.51 mg), Rha2C10 (0.12 mg), RhaC10C12 (1.26 mg), Rha2C10C10 (1.03 mg), and Rha2C10C12 (0.87 mg) were extracted from prepared Pseudomonas aeruginosa (100.0 mg) with purities of 96.37, 95.20, 91.25, 84.41, 89.8, and 90.26%, respectively. The purified compounds were identified by high-performance liquid chromatography/mass spectroscopy, plus 1H and 13C nuclear magnetic resonance studies. This study provides a new perspective on concepts involving efficient solvent system selection.
Face recognition using PCA and SVM (2009)

Automatic recognition of people has received much attention during the recent years due to its many applications in different fields such as law enforcement, security applications or video indexing. Face recognition is an important and very challenging technique to automatic people recognition. Up to date, there is no technique that provides a robust solution to all situations and different applications that face recognition may encounter. In general, we can make sure that performance of a face recognition system is determined by how to extract feature vector exactly and to classify them into a group accurately. It, therefore, is necessary for us to closely look at the feature extractor and classifier. In this paper, Principle Component Analysis (PCA) is used to play a key role in feature extractor and the SVMs are used to tackle the face recognition problem. Support Vector Machines (SVMs) have been recently proposed as a new classifier for pattern recognition. We illustrate the potential of SVMs on the Cambridge ORL Face database, which consists of 400 images of 40 individuals, containing quite a high degree of variability in expression, pose, and facial details. The SVMs that have been used included the Linear (LSVM), Polynomial (PSVM), and Radial Basis Function (RBFSVM) SVMs. We provide experimental evidence which show that Polynomial and Radial Basis Function (RBF) SVMs performs better than Linear SVM on the ORL Face Dataset when both are used with one against all classification. We also compared the SVMs based recognition with the standard eigenface approach using the Multi-Layer Perceptron (MLP) Classification criterion.
Differential Effects of Gonadotropin-Releasing Hormone (GnRH)-I and GnRH-II on Prostate Cancer Cell Signaling and Death (2005)

This study suggests the existence of a novel GnRH-II binding protein, in addition to a conventional GnRH-I receptor, in prostate cancer cells. These data may facilitate the development of innovatory therapeutic drugs for the treatment of prostate cancer.
Basal Ganglia Volume and Shape in Children With Attention Deficit Hyperactivity Disorder (2008)

The shape compression pattern of basal ganglia in boys with ADHD suggests that ADHD-associated deviations from typical brain development involve multiple frontal-subcortical control loops, including circuits with premotor, oculomotor, and prefrontal cortices. Further investigations employing brain-behavior analyses will help to discern the task-dependent contributions of these circuits to impaired response control that is characteristic of ADHD.
Versatile Set of Orthogonal Protecting Groups for the Preparation of Highly Branched Oligosaccharides (2010)

A new set of orthogonal protecting groups has been developed based on the use of a diethylisopropylsilyl (DEIPS), methylnaphthyl (Nap), allyl ether, and levulinoyl (Lev) ester. The protecting groups are ideally suited for the preparation of highly branched oligosaccharides and their usefulness has been demonstrated by the chemical synthesis of a β-D-Man-(1→4)-D-Man disaccharide, which is appropriately protected for making a range of part-structures of the unusual core region of the lipopolysaccharide of Francisella tularensis.
Predicting frequency of suicide attempts of adolescent outpatients at Weskoppies Hospital using clinical and demographic characteristics (2012)

<p>The prevention of suicide, particularly adolescent suicide, remains one of the biggest challenges in psychiatry.</p><p><strong>Objectives. </strong>To ascertain: (i) clinical and demographic characteristics; and (ii) possible associations between these characteristics and suicide attempt frequency in a selected patient group at Weskoppies Hospital over 4 months.</p><p><strong>Methods.</strong> Fifty adolescent outpatients aged between 13 and 17 years with a history of one or more suicide attempts were interviewed to obtain demographic and clinical features. Chi square and Fisher’s exact tests assessed associations between these features and suicide attempt frequency. <strong></strong></p><p><strong>Results.</strong> Of the subjects, 79% were aged between 15 and 17 years; they were predominantly female (62%) and Caucasian (83%). Mainstream and special education schools were equally represented. Three-quarters had reached grades 8 - 10, and 14% lived with both biological parents, 33% in places of safety and 37% with one divorced parent. The minority of caregivers had a history of alcohol abuse and other substance use. Twenty-nine per cent of the subjects had attempted suicide on more than 10 occasions and 23% had made a single attempt. The most common methods were wounding (74%), tablet overdose (34%) and hanging (20%). Psychiatric diagnoses included major depressive disorder (64%), bipolar disorder (38%), alcohol abuse (18%) and other substance abuse (24%). Familial features included depression, substance abuse, antisocial behaviour and suicide. Familial suicidal behaviour included suicide attempts by parents (85%), siblings (36%), aunts and uncles (31%) and cousins (44%). Physical and sexual abuse was reported in 52% of families. Conclusion. Many findings and profiles of other studies were confirmed and point to school and home environments, family psychopathology and psychiatric diagnoses as factors associated with adolescent suicide attempts. Associations between the frequency of suicide attempts and the demographic and clinical characteristics were statistically inconclusive.</p>
Downstream Processing of Recombinant Proteins from Transgenic Plant Systems: Phenolic Compounds Removal from Monoclonal Antibody Expressing Lemna minor and Purification of Recombinant Bovine Lysozyme from Sugarcane (2012)

Transgenic plant systems have been proposed as bioreactors in the production of pharmaceutical and industrial proteins. The economic benefits of inexpensive plant production systems could be erased if the downstream processing ends up being expensive.\nTo avoid monoclonal antibody (mAb) modification or fouling of chromatography resins, removal of phenolics from plant extracts is desirable. Removal of major phenolics in Lemna extracts was evaluated by adsorption to PVPP, XAD-4, IRA-402 and Q-Sepharose resins. Analysis of phenolics adsorption to XAD-4, IRA-402 and Q-Sepharose showed superior dynamic binding capacities at pH 4.5 than at 7.5. The economic analysis using SuperPro Designer 7.0 indicated that addition of a phenolics adsorption step would increase mAb production cost only 20% by using IRA-402 compared to 35% for XAD-4 resin. The overall mAb processing cost can be reduced by implementing a phenolics removal step.\nTo understand phenolics-resin interactions, adsorption isotherms of phenolic compounds (chlorogenic acid, ferulic acid, rutin, syringic acid and vitexin-2-O-rhamnoside) from different phenolic classes on three resins (IRA-402, PVPP, XAD-4) at pH 4.5 and 7.5 were determined. Differences in adsorption with the type of phenolics were observed, and PVPP was not efficient for phenolics removal. \nScreening of sugarcane lines for bovine lysozyme (BvLz) accumulation indicated that expression levels are still inadequate for commercial development. To maximize BvLz extraction, pH and ionic strength were evaluated; five conditions resulted in equivalent BvLz/TSP ratio. Membrane filtration process using BvLz extracts attained partial removal of native proteins by the 100 kDa membrane step, but also BvLz loss (21-29%). Regardless of the extraction condition, at least 47% of the starting BvLz was lost during the membrane processing. None of the evaluated extraction conditions caused a substantial recovery of BvLz in the concentrate.\nAlternative purification options for the IEX+HIC process, which achieved 95% BvLz purity, were tested. Direct loading of sugarcane extract concentrate on HIC and XAD-4 pretreatment of juice did not recovered BvLz as effectively as the IEX chromatography. Pure BvLz was obtained by the XAD+HIC process, but higher purification fold and HIC yield were achieved by the IEX+HIC process, due to the complete separation of BvLz and 18-kDa protein.
Mechanisms, Pathophysiology, and Management of Obesity (2017)

Obesity is prevalent in the U.S. population and contributes significantly to morbidity and mortality. Treatments include behavioral therapy, pharmacotherapy, and bariatric surgery. Some sequelae of obesity are reversed with weight loss. Maintaining weight loss is a challenge.
Air quality in the Daspoort Tunnel : a multidisciplinary, multi-institution collaboration : environmental science (2011)

Road tunnels with pedestrian walkways may pose a risk to the health of drivers, pedestrians and cyclists. In this study, a unique team of scientists, university students and school geographers worked together to assess air quality and vehicle and pedestrian traffic in the Daspoort Tunnel, Pretoria.
ISAC: Integrated Space-and-Time-Adaptive Chip-Package Thermal Analysis (2007)

Ever-increasing integrated circuit (IC) power densities and peak temperatures threaten reliability, performance, and economical cooling. To address these challenges, thermal analysis must be embedded within IC synthesis. However, this requires accurate three-dimensional chip-package heat flow analysis. This has typically been based on numerical methods that are too computationally intensive for numerous repeated applications during synthesis or design. Thermal analysis techniques must be both accurate and fast for use in IC synthesis. This paper presents a novel accurate incremental spatially and temporally adaptive chip-package thermal analysis technique called ISAC for use in IC synthesis and design. It is common for IC temperature variation to strongly depend on position and time. ISAC dynamically adapts spatial- and temporal-modeling granularities to achieve high efficiency while maintaining accuracy. Both steady-state and dynamic thermal analyses are accelerated by the proposed heterogeneous spatial-resolution adaptation and asynchronous thermal-element time-marching techniques. Each technique enables orders-of-magnitude improvement in performance while preserving accuracy when compared with other state-of-the-art adaptive steady-state and dynamic IC thermal analysis techniques. Experimental results indicate that these improvements are sufficient to make accurate dynamic and steady-state thermal analysis practical within the inner loops of IC synthesis algorithms. ISAC has been validated against reliable commercial thermal analysis tools using industrial and academic synthesis test cases and chip designs. It has been implemented as a software package suitable for integration in IC synthesis and design flows and has been publicly released
Anaphylatoxin-mediated regulation of the immune response. I. C3a-mediated suppression of human and murine humoral immune responses. (1982)

The C3a fragment of the third component of complement was found to have immunosuppressive properties. C3a is capable of suppressing both specific and polyclonal antibody responses. In contrast, C3a had no effect on antigen- or mitogen-induced B or T cell proliferative responses. The carboxy-terminal arginine is essential for C3a to exhibit its immunosuppressive properties. The serum carboxypeptidase inhibitor 2-mercaptomethyl-5-guanodinopentanoic acid, which prevents cleavage of the terminal arginine that would produce C3ades Arg-77, allowed us to assay the effects of C3a on in vitro immune response systems where serum is required. When the terminal arginine is removed from C3a, the resulting C3ades Arg-77 molecule is nonsuppressive. Helper T lymphocytes are the target of C3a-mediated suppression of the immune response. Substitution of T cells by soluble T cell factors was found to abrogate the C3a suppressive activity.