gebhart/patrepeval huggingface dataset:
Inkjet Printing of Regenerated Silk Fibroin: From Printable Forms to Printable Functions (2015)

A formulation of regenerated silk fibroin solution that can be easily functionalized and inkjet printed on numerous surfaces is developed. As an example, the inks can be printed on laboratory gloves that change color when exposed to bacteria.
Adaptive digital precoder codebook resolution for millimeter wave hybrid beamforming (2017)

Hybrid analog-digital beamforming has emerged as an important technique to enable millimeter wave (mmWave) communications in 5G radio access networks. With a two-stage hybrid beamforming procedure, where analog and digital precoders are determined separately and sequentially, the benefits attributed to digital precoding on top of analog beams could be quite marginal in some cases, as sparse propagation paths in a mmWave channel could be well captured by analog beams alone. By exploiting such characteristic, this paper proposes a digital precoder codebook resolution adaptation scheme, wherein a user device is able to determine the digital precoder resolution based on the gain in addition to analog beamforming, in order to reduce feedback overhead without significant performance degradation.
Salivary Fluoride from Fluoride Dentifrices or Rinses after Use of a Calcium Pre-Rinse or Calcium Dentifrice (2006)

The low concentration of available calcium (Ca) in oral fluids limits the formation of Ca-mediated fluoride deposits that maintain oral fluoride (F) after a topical F treatment. The purpose of this study was to examine if a high concentration of Ca would increase salivary F when used before a F rinse or dentifrice. We found that a Ca pre-rinse (150 mmol/l Ca lactate) or Ca dentifrice (0.084 g Ca glycerolphosphate per gram dentifrice) used immediately before a 60 s 228-ppm F rinse (12 mmol/l NaF) produced a 4.6x or 3.6x increase (p < 0.05) respectively in the 1 h salivary F concentrations over the F rinse alone. Reducing the post-Ca F rinse to 10 s still produced a significant 2.2x increase in salivary F compared to the 60 s F rinse alone. Used with a conventional 1,100 ppm F (i.e. 1,100 microg F per gram) NaF dentifrice (Crest), the above Ca pre-rinse increased 1 h salivary F levels by 2.3x over the F dentifrice alone. However, a F rinse given before a Ca rinse produced no increase in 1 h salivary F concentrations. Although the persistence of these increases requires further study, these results suggest that a moderately high concentration of Ca given shortly before a F rinse or F dentifrice may increase the cariostatic effect of the F product.
De novo design of programmable inducible promoters (2019)

Ligand-responsive allosteric transcription factors (aTF) play a vital role in genetic circuits and high-throughput screening because they transduce biochemical signals into gene expression changes. Programmable control of gene expression from aTF-regulated promoter is important because different downstream effector genes function optimally at different expression levels. However, tuning gene expression of native promoters is difficult due to complex layers of homeostatic regulation encoded within them. We engineered synthetic promoters de novo by embedding operator sites with varying affinities and radically reshaped binding preferences within a minimal, constitutive Escherichia coli promoter. Multiplexed cell-based screening of promoters for three TetR-like aTFs generated with this approach gave rich diversity of gene expression levels, dynamic ranges and ligand sensitivities and were 50- to 100-fold more active over their respective native promoters. Machine learning on our dataset revealed that relative position of the core motif and bases flanking the core motif play an important role in modulating induction response. Our generalized approach yields customizable and programmable aTF-regulated promoters for engineering cellular pathways and enables the discovery of new small molecule biosensors.
New Fluorocarbofunctional Spherosilicates: Synthesis and Characterization (2011)

Very efficient syntheses of new fluorocarbofunctional silsesquioxanes (spherosilicates) were performed via direct hydrosilylation with octakis(hydrospherosilicate) catalyzed by [Rh(μ-OSiMe3)(cod)2]2. This method appeared to be very effective for successive (tandem) hydrosilylation of two different olefins, which permits almost quantitative syntheses of spherosilicates with mixed fluoropentyloxypropyl and glicydoxypropyl functional groups of desired stoichiometric ratios. All newly synthesized compounds were isolated and characterized by spectroscopic methods.
Differential Mathematical Morphological-Based Online Diagnosis of Stator Interturn Failures in Direct Torque Control Drive Systems (2020)

This article presents an in-service noninvasive fault diagnosis (FD) routine to detect incipient stator's interturn failure (ITF) in the direct torque control (DTC) driven induction motors. The developed FD routine is based on the application of the mathematical morphological gradient (MMG) technique on the stator currents. Being a time-domain technique, it is less computational burdensome than the frequency-domain-based FD. To detect the faulty phase, we introduced and implemented the differential MMG (ΔMMG) algorithm concept. A comprehensive electromagnetic investigation of harmonics and interharmonics contents due to the ITF, the DTC controller's reaction, the inverter's switching activity is presented. A design guideline of selecting the structuring element length in the FD routine was introduced. A physics-based cosimulation platform was built to investigate the feasibility of the proposed FD algorithm. The simulation reinforced by the experimental results depicted the robustness of the FD method. The comparative analysis is presented between the developed ΔMMG and the conventional motor current signature analysis (MCSA). The experimental results proved that developed FD is faster and more robust than the MCSA in detecting the ITFs at their embryonic stages.
Identification of complex genomic breakpoint junctions in the t(9;11) <i>MLL‐AF9</i> fusion gene in acute leukemia (1997)

The MLL gene at chromosome 11, band q23, is involved in translocations with as many as 40 different chromosomal bands. Virtually all breakpoints occur within an 8.3 kb BamHI fragment and result in 5' MLL fused to partner genes in a 5'-3' orientation. The translocation t(9;11)(p22;q23), which results in the fusion of MLL to AF9, is the most common of the 11q23 chromosomal abnormalities observed in de novo acute myeloid leukemia (AML), in therapy related leukemia (t-AML), and rarely in acute lymphoblastic leukemia (ALL). We have studied 24 patients with a t(9;11) and an MLL rearrangement, including 19 patients with AML, four with t-AML, and one with ALL. To understand the mechanisms of this illegitimate recombination, we cloned and sequenced the t(9;11) translocation breakpoint junctions on both derivative chromosomes from one AML patient and from the Mono Mac 6 (MM6) cell line, which was derived from a patient with AML. Two different complex junctions were noted. In the AML patient, both chromosome 11 and 9 breaks were staggered, occurred in Alu DNA sequences, and resulted in a 331 bp duplication. In the MM6 cell line, breaks in chromosomes 11 and 9 were also staggered, but, in contrast to the finding in the AML patient, the breaks did not involve Alu DNA sequences and resulted in a 664 bp deletion at the breakpoints. Using reverse transcriptase (RT-) PCR, we analyzed 11 patient samples, including the two just described, for MML-AF9 fusions. The fusion occurred in six of seven AML patients, two of two t-AML patients, one patient with ALL, and in the MM6 cell line. Interestingly, all of the breaks within the AF9 gene in AML patients occurred in the central AF9 exon, called Site A by others, whereas in the single ALL patient the breakpoint mapped to a more 3' region of the AF9 gene. Our data, when combined with those of others, suggest that the fusion point within the AF9 gene, and thus the amount of AF9 material included in the MLL-AF9 fusion gene product, may influence the phenotype of the resulting leukemia. This further supports the proposal that the MML translocation partner genes play a critical role in the leukemogenic process.
Class D Amplifier with Ripple Steering (2007)

This paper shows the application of ripple steering to a Class D audio power amplifier for the reduction of the switching ripple residual. Several topologies are presented for use in different applications. The ripple steering enhances the performance with respect to electromagnetic compatibility, allows reduced switching losses, and enables more accurate audio test and measurement. A method is presented to further linearize and extend the bandwidth of the Class D audio power amplifier which is made practical by switching ripple reduction.
Abstract 16199: Optimization of Reconstruction and Quantification for Motion-Corrected Coronary 18F-NaF PET (2017)

Introduction: Coronary PET has shown promise in the detection of high-risk plaques; however, there is a need to optimize imaging techniques to improve quantitation and overcome challenges faced by ...
Sulfide Scale Control: A High Efficacy Breakthrough Using an Innovative Class of Polymeric Inhibitors (2014)

Abstract Prevention of sulfide scale through the use of chemistry is a developing area of focus within the oil industry. There are few examples of a single chemical approach working, where scale inhibitor species function at threshold concentrations. Partial inhibition may be provided by ‘standard’ scale inhibitors using established chemistries such as phosphonates or polymeric species. However, the efficacy of these inhibitors against sulfide scale is generally poor and high concentrations are typically required. Based on an industry need for a true, high-performance sulfide scale inhibitor, work was undertaken to develop a novel chemistry that would offer a step-change in performance from existing technologies. Using a new advanced rapid screening technique, a wide range of ‘standard’ scale inhibitors were assessed, which proved that the majority of these chemistries display no efficacy against sulfide scale. A select few of the standard scale inhibitors displayed limited efficacy and from this data common molecular features which contributed to sulfide scale inhibition were identified. Utilizing this knowledge, a range of novel polymeric chemistries were synthesized which provide significantly superior inhibition than any other postulated for this application. It has been possible to identify specific moieties within these complex polymers which are required for sulfide scale inhibition and to theorize on likely molecular structure-performance relationships for this new class of scale inhibitor. Additionally, hypotheses on the specific mechanisms by which these inhibitors function have been provided, showing why they are so successful at sulfide crystal growth retardation. Static and dynamic test methods are described that accurately mimic formation of these scales in the field, in comparing the novel polymeric chemistry with the best-performing ‘standard’ scale inhibitors. Order of magnitude increases in performance over standard species are reported which represents a true step-change in the efficacy of sulfide scale inhibition.
A Practical Bin-Picking System Using 3D Object Recognition (2001)

We present a practical bin-picking system that uses stereo vision from multiple viewpoints and the three-dimensional recognition using salient features and uncertainty evaluation. First, the salient features of objects in images are extracted. Under the guidance of the features, the two-dimensional object candidates are detected. And the feature correspondence among stereo images is made based on the global features of an object model. Second, the three-dimensional features are reconstructed using the stereo vision results. Next, with the object features and the three-dimensional measurements, the uncertainty is evaluated. Then the results from the different viewpoints are integrated to determine the optimal results for each object by using the uncertainty and the three-dimensional position of object candidates. Based on this practical three-dimensional vision, an intelligent robot system is realized to pick up objects in a bin.
Band excitation in scanning probe microscopy: sines of change (2011)

In the three decades since scanning probe microscopy (SPM) methods have entered the scientific arena, they have become one of the main tools of nanoscale science and technology by offering the capability for imaging topography, magnetic, electrical and mechanical properties on the nanometre scale. The vast majority of force-based SPM techniques to date are based on single-frequency sinusoidal excitation and detection. Here, we illustrate the intrinsic limitations of single-frequency detection that stem from the fundamental physics of dynamic systems. Consequently, many aspects of nanoscale materials functionality including quantitative mechanical, magnetic and electrical measurements, as well as probing dissipative interactions, remain unexplored. Band excitation is illustrated as a universal alternative to traditional single-frequency techniques that allows quantitative and reliable studies of dissipative and conservative phenomena, and can be universally applied to all ambient and liquid SPM methods.
Increased K+ Efflux and Apoptosis Induced by the Potassium Channel Modulatory Protein KChAP/PIAS3β in Prostate Cancer Cells (2002)

K(+) channel-associated protein/protein inhibitor of activated STAT (KChAP/PIAS3beta) is a potassium (K(+)) channel modulatory protein that boosts protein expression of a subset of K(+) channels and increases currents without affecting gating. Since increased K(+) efflux is an early event in apoptosis, we speculated that KChAP might induce apoptosis through its up-regulation of K(+) channel expression. KChAP belongs to the protein inhibitor of activated STAT family, members of which also interact with a variety of transcription factors including the proapoptotic protein, p53. Here we report that KChAP induces apoptosis in the prostate cancer cell line, LNCaP, which expresses both K(+) currents and wild-type p53. Infection with a recombinant adenovirus encoding KChAP (Ad/KChAP) increases K(+) efflux and reduces cell size as expected for an apoptotic volume decrease. The apoptosis inducer, staurosporine, increases endogenous KChAP levels, and LNCaP cells, 2 days after Ad/KChAP infection, show increased sensitivity to staurosporine. KChAP increases p53 levels and stimulates phosphorylation of p53 residue serine 15. Consistent with activation of p53 as a transcription factor, p21 levels are increased in infected cells. Wild-type p53 is not essential for induction of apoptosis by KChAP, however, since KChAP also induces apoptosis in DU145 cells, a prostate cancer cell line with mutant p53. Consistent with its proapoptotic properties, KChAP prevents growth of DU145 and LNCaP tumor xenografts in nude mice, indicating that infection with Ad/KChAP might represent a novel method of cancer treatment.
Characterizing Online Discussions in Microblogs Using Network Analysis (2013)

Online discussions of a specific topic in microblogs may vary widely in their content, locality, and participants. We describe a method for analyzing microblog discussions in Twitter, using a network model in order to characterize discussions by their network properties. Building the network from participants, their messages, their locations, and shared message content, we present an analysis of six network features over four types of discussions. Our analysis reveals that the diameter of the discussion network, when normalized for size, provides a strong indicator for the level of concentration around a few items. In addition, we show that different discussion types show clear patterns in how their entities (e.g., participants, locations) vary over time in importance to the discussion. Our analysis identifies clear measures for quantifying and categorizing novel discussions in terms of their important features and expected dynamics.
Highly Active Copper-Based Catalyst for Atom Transfer Radical Polymerization (2006)

Atom transfer radical polymerization (ATRP) generally requires a catalyst/initiator molar ratio of 0.1 to 1 and catalyst/monomer molar ratio of 0.001 to 0.01 (i.e., catalyst concentration: 1000-10,000 ppm versus monomer). Herein, we report a new copper-based complex CuBr/N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine (TPEN) as a versatile and highly active catalyst for acrylic, methacrylic, and styrenic monomers. The catalyst mediated ATRP at a catalyst/initiator molar ratio of 0.005 and produced polymers with well-controlled molecular weights and low polydispersities. ATRP occurred even at a catalyst/initiator molar ratio as low as 0.001 with copper concentration in the produced polymers as low as 6-8 ppm (catalyst/monomer molar ratio = 10(-5)). The catalyst structures were studied by X-ray diffraction and NMR spectroscopy. The activator CuIBr/TPEN existed in solution as binuclear and mononuclear complexes in equilibrium but as a binuclear complex in its single crystals. The deactivator CuIIBr2/TPEN complex was mononuclear. High stability and appropriate KATRP (ATRP equilibrium constant) were found crucial for the catalyst working under high dilution or in coordinating solvents/monomers. This provides guidance for further design of highly active ATRP catalysts.
RODbaffle heat exchanger technology (1990)

The RODbaffle heat exchanger concept was conceived in 1970 as a means of eliminating the destructive, flow-induced tube vibrations that exist in conventional, plate-baffle heat exchangers. The early RODbaffle design utilized elliptically shaped baffle rings oriented at 45{degrees} angles from the tube bundle axis; intersecting pairs of baffles contained either horizontal or vertical support rods located between each tube row. In addition to solving the existing tube vibration problem, this early RODbaffle exchanger exhibited reduced shellside pressure losses and increased thermal performance. Subsequent research efforts have resulted in a simplified RODbaffle design concept and have established thermal-hydraulic predictive methods. This paper describes various aspects of current RODbaffle heat exchanger technology.
Clinical Aspects of Parathyroid Hypertensive Factor (1994)

Parathyroid hypertensive factor (PHF) in rats: PHF is an endogenous hypertensive substance which was originally associated with hypertension in spontaneously hypertensive rats (SHR). In this model, PHF was shown to act by increasing intracellular calcium levels in vascular smooth muscle and was linked with a characteristic pattern of abnormalities in overall calcium regulation. The action of PHF was blocked by calcium antagonists, suggesting that the effect of PHF was to increase extracellular calcium uptake. In SHR the parathyroid glands were shown to be the site of PHF secretion. This secretion was inhibited by an increase in dietary calcium. PHF was further shown to be unique to low-renin forms of hypertension, that is, those forms of hypertension characterized by abnormalities in calcium metabolism. PHF in humans: PHF was subsequently found in human low-renin salt-sensitive hypertension. As in SHR, calcium supplementation can lower PHF levels in humans. Similarly, there is circumstantial evidence for the parathyroid origin of PHF in humans. In human hypertensive patients, the presence of PHF has been shown to predict a favorable therapeutic response to calcium channel blockade. Recently, many of the abnormalities in calcium metabolism present in low-renin hypertension have also been described in other disease states. Notable among these diseases is non-insulin dependent diabetes mellitus. A survey of human non-insulin dependent diabetes mellitus has revealed that PHF was present in a disproportionate number of these patients independently of the blood pressure level. The significance of this latter finding needs to be explored, but PHF may prove to have relevance in diseases other than hypertension.(ABSTRACT TRUNCATED AT 250 WORDS)
Permeation of Gas Mixtures in Cellulose Acetate Membranes Practical Approach to Predict the Permeation Rate Co<sub>2</sub>/Ch<sub>4</sub>Mixture (1988)

Abstract Dry cellulose acetate reverse osmosis membranes of different porosities are prepared by using the solvent exchange method and then shrunk at various temperatures.
Time‐lapse changes in tube and guided waves in cross‐well Mallik experiment (2006)

We analyze cross‐well seismic data from the Mallik experiment and demonstrate time‐lapse changes in tube and guided waves. Although such changes are challenging to interpret, they are generally of a larger magnitude compared to any time‐lapse signatures of the first P‐wave arrivals reported elsewhere. This suggests better sensitivity of tube and guided waves to small production‐related changes and their feasibility for reservoir monitoring.
Steerable pyramids for image decomposition and enhancement (1991)

We have previously described 1 the use of steerable filters, in which a small set of oriented basis filters are used to analyze images in a uniform and efficient manner. Filters of arbitrary orientation can be synthesized as linear combinations of the basis filters. We now describe a multiscale pyramid decomposition using steerable filters. The steerable pyramid breaks an image down into a set of bandpassed subimages; the subimages at a given level of the pyramid form a steerable set. The steerable pyramid is overcomplete and therefore nonorthogonal. However, it is self-inverting, meaning that the analysis functions used to build the pyramid are the same as the synthesis functions used to reconstruct. We have implemented image noise cleaning within this representation. The pyramid is used to analyze local image orientation. Neighborhoods with strong orientation are likely to represent image structure, while neighborhoods with little or no orientation are likely to represent noise. The pyramid coefficients are modified according to the likelihood that they represent image or noise. The pyramid transform is then inverted, producing a cleaned image.