gebhart/patrepeval huggingface dataset:
Synthesis and physical studies of azamitosene and iminoazamitosene reductive alkylating agents. Iminoquinone hydrolytic stability, syn/anti isomerization, and electrochemistry (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis and physical studies of azamitosene and iminoazamitosene reductive alkylating agents. Iminoquinone hydrolytic stability, syn/anti isomerization, and electrochemistryImadul Islam and Edward B. SkiboCite this: J. Org. Chem. 1990, 55, 10, 3195–3205Publication Date (Print):May 1, 1990Publication History Published online1 May 2002Published inissue 1 May 1990https://pubs.acs.org/doi/10.1021/jo00297a040https://doi.org/10.1021/jo00297a040research-articleACS PublicationsRequest reuse permissionsArticle Views409Altmetric-Citations27LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A compressed domain beat detector using MP3 audio bitstreams (2001)

This paper presents a novel beat detector that processes MPEG-1 Layer III (known as MP3) encoded audio bitstreams directly in the compressed domain. Most previous beat detection or tracking systems dealing with MIDI or PCM signals are not directly applicable to compressed audio bitstreams, such as MP3 bitstreams. We have developed the beat detector as a part of a beat-pattern based error concealment scheme for streaming music over error prone channels. Special effort was used to obtain a tailored trade-off between performance, complexity and memory consumption for this specific application. A comparison between the machine-detected results to the human annotation has shown that the proposed method correctly tracked beats in 4 out of 6 popular music test signals. The results were analyzed.
Servo tuning and stabilization of nonlinear optical crystals (1979)

A new optical technique for servo tuning and stabilization of angle tuned nonlinear optical crystals is described. This technique has zero insertion loss and works equally well with collimated, focused, or noncollinear fundamental beams. Servo tuning of a Type I KDP nonlinear crystal for summing the output of a tunable dye laser with the Nd:YAG second harmonic and servo stabilization of the production of the Nd:YAG fourth harmonic in Type I KDP are demonstrated.
Specific binding of human immunodeficiency virus type 1 gag polyprotein and nucleocapsid protein to viral RNAs detected by RNA mobility shift assays (1993)

Packaging of retroviral genomic RNA during virion assembly is thought to be mediated by specific interactions between the gag polyprotein and RNA sequences (often termed the psi or E region) near the 5' end of the genome. For many retroviruses, including human immunodeficiency virus type 1 (HIV-1), the portions of the gag protein and the RNA that are required for this interaction remain poorly defined. We have used an RNA gel mobility shift assay to measure the in vitro binding of purified glutathione S-transferase-HIV-1 gag fusion proteins to RNA riboprobes. Both the complete gag polyprotein and the nucleocapsid (NC) protein alone were found to bind specifically to an HIV-1 riboprobe. Either Cys-His box of NC could be removed without eliminating specific binding to the psi riboprobe, but portions of gag containing only the MA and CA proteins without NC did not bind to RNA. There were at least two binding sites in HIV-1 genomic RNA that bound to the gag polyprotein: one entirely 5' to gag and one entirely within gag. The HIV-1 NC protein bound to riboprobes containing other retroviral psi sequences almost as well as to the HIV-1 psi riboprobe.
A network flow framework for online dynamic channel allocation (2002)

We present a framework based on network flows for dynamic channel allocation. The framework allows us to gracefully extend previously proposed heuristics, while avoiding the problems associated with the optimal packing schemes. The framework is shown to yield parametrizable algorithms that tradeoff the benefit of channel reassignments with the costs. Channel reassignments are allowed to be performed not just at new call arrivals, but also at various other trigger points like call terminations and channel quality deterioration.
Experimental Study on the Thermal Characteristics of a Colloidal Damper (2010)

Lately, ecological and intelligent colloidal dampers based on the liquid penetration/exudation in/from lyophobic nanoporous solids were proposed. Although colloidal dampers could be attractive for various applications, they are still under research, since some unexpected findings await satisfactory explanation. For instance, colloidal dampers are able to dissipate large amounts of mechanical energy without significant heating, and such result is surprising since traditional absorbers transform almost integrally the dissipated energy into heat. In this work, using a digital infrared-camera, the temperature distribution on the external surface of a colloidal damper is recorded versus the working time and the positions of the main heat sources are identified. Such experiments allow evaluation of the temperature inside the colloidal damper's working cylinder and the absorber's generated heat. Introducing the colloidal damper inside of an incubator, variation of the hysteresis shape and dissipated energy versus the working temperature can be found. From such experimental results, ratio of the generated heat to the dissipated energy is evaluated.
Comparison of pharmacokinetics and biological activity of two IL-15 heterodimeric forms in mice and macaques (P6356) (2013)

Abstract IL-15 is a member of the γ-chain family of cytokine important for the proliferation and function of NK and T cells. IL-15 acts on the surface of the cell in complex with IL-15Rα to engage IL-15Rβγ complex in nearby cells. We recently showed that in both murine and human sera IL-15 is in complex with soluble IL-15Rα (sIL-15Rα), suggesting that IL-15/IL-15Rα heterodimer is responsible for IL-15 bioactivity in vivo. We have generated stable cell lines secreting high levels of fully processed human IL-15/sIL-15Rα cytokine. We also prepared an additional form of human glycosylated IL-15 heterodimer in which the C-terminus of sIL-15Rα is fused to the Fc region of human IgG1. The biochemical properties and bioactivity of these IL-15 heterodimers were tested in mice and macaques. IL-15/IL-15RαFc was characterized by an increased bioactivity that reflected its superior plasma half-life in mice, in comparison to IL-15/sIL-15Rα. However, delivery of these two IL-15 heterodimers in macaques failed to reveal any major differences in their pharmacokinetic and pharmacodynamic profile. In macaques, both IL-15 heterodimeric forms resulted in similar levels of plasma IL-15 and induced similar proliferation of NK, γδ and CD8+ T cells. Also, both IL-15 heterodimers were effective in reducing tumor burden in a colon carcinoma mouse model. These results provide important insights for the choice of IL-15 for clinical use, and suggest caution when interpreting data using IL-15/IL-15RαFc in mice.
Long-term stabilization of the phase control technique of the stimulated Brillouin scattering wave for the beam combination technique (2007)

The beam combination technique using stimulated Brillouin scattering (SBS) phase conjugate mirrors (PCMs) proposed by one of the authors, H. J. Kong, is a promising one for realization of high energy/power laser system with high repetition rate. However, phase controlling of the SBS waves is essentially required for beam combination system, since the SBS-PCM generates the random phase. Recently, we have achieved successful results for phase locking by the self-generated density modulation method. But it showed a long-term phase fluctuation due to the long-term fluctuation of the density of the liquid SBS medium. To compensate this long-term phase fluctuation, we have designed new phase stabilization system. In this paper, we will introduce this system and show successful experimental results.
Tree structured wavelet transform segmentation of microcalcifications in digital mammography (1995)

A novel multistage algorithm is proposed for the automatic segmentation of microcalcification clusters (MCCs) in digital mammography. First, a previously reported tree structured nonlinear filter is proposed for suppressing image noise, while preserving image details, to potentially reduce the false positive (FP) detection rate for MCCs. Second, a tree structured wavelet transform (TSWT) is applied to the images for microcalcification segmentation. The TSWT employs quadrature mirror filters as basic subunits for both multiresolution decomposition and reconstruction processes, where selective reconstruction of subimages is used to segment MCCs. Third, automatic linear scaling is then used to display the image of the segmented MCCs on a computer monitor for interpretation. The proposed algorithms were applied to an image database of 100 single view mammograms at a resolution of 105 microns and 12 bits deep (4096 gray levels). The database contained 50 cases of biopsy proven malignant MCCs, 8 benign cases, and 42 normal cases. The measured sensitivity (true positive detection rate) was 94% with a low FP detection rate of 1.6 MCCs/image. The image details of the segmented MCCs were reasonably well preserved, for microcalcification of less than 500 microns, with good delineation of the extent of the microcalcification clusters for each case based on visual criteria.
Real Time Capture of Audio Images and their Use with Video (2007)

Spherical microphone arrays provide an ability to compute the acoustical intensity corresponding to different spatial directions in a given frame of audio-data. These intensities may be exhibited as an image and these images updated at a high frame rate to achieve a video stream if the data capture and intensity computations can be performed sufficiently quickly, there by creating a frame-rate audio camera. We describe how such a camera can be built and the processing done sufficiently quickly using graphics processors. The joint processing of captured frame-rate audio and video images enables applications such as visual identification of noise sources, beamforming and noise-suppression in video conferencing and others, provided it is possible to account for the spatial differences in the location of the audio and the video cameras. Based on the recognition that the spherical array can be viewed as a central projection camera it is possible to perform such joint analysis. We provide several examples of real-time applications.
Antenna design for microwave hepatic ablation using an axisymmetric electromagnetic model (2006)

This paper emphasizes the importance of factors that can affect simulation accuracy, which include boundary conditions, the dielectric properties of liver tissue, and mesh resolution.
Efficient shared cache management through sharing-aware replacement and streaming-aware insertion policy (2009)

Multi-core processors with shared caches are now commonplace. However, prior works on shared cache management primarily focused on multi-programmed workloads. These schemes consider how to partition the cache space given that simultaneously-running applications may have different cache behaviors. In this paper, we examine policies for managing shared caches for running single multi-threaded applications. First, we show that the shared-cache miss rate can be significantly reduced by reserving a certain amount of space for shared data. Therefore, we modify the replacement policy to dynamically partition each set between shared and private data. Second, we modify the insertion policy to prevent streaming data (data not reused before eviction) from promoting to the MRU position. Finally, we use a low-overhead sampling mechanism to dynamically select the optimal policy. Compared to LRU policy, our scheme reduces the miss rate on average by 8.7% on 8MB caches and 20.1% on 16MB caches respectively.
Blind UWB timing with a dirty template (2004)

Ultra-wideband (UWB) radio is gaining increasing attention thanks to its attractive features that include low-power low-complexity baseband operation and ample multipath diversity. Realization of its potential, however, faces the challenge of low-complexity high-performance timing acquisition. In this paper, we develop a blind timing acquisition algorithm for frame-level synchronization. Relying on simple integrate-and-dump operations over one symbol duration, our algorithm exploits the rich multipath diversity enabled by UWB transmissions. It outperforms existing blind algorithms and has comparable performance to data-aided ones. Equally attractive is its applicability to UWB links with or without time hopping (TH), over frequency-flat or multipath channels. It is also worth stressing that our "dirty" template based scheme is able to achieve timing synchronization at any desirable resolution and is readily applicable to non-UWB systems, so long as intersymbol interference is absent.
Digital Holography of Aerosol Particles (2017)

This work combines digital holography with spatial filtering at two wavelengths to record the hologram and light-scattering pattern for single micrometer-sized aerosol particles using a color sensor. The results demonstrate the ability to unambiguously associate a complex scattering pattern with the particle size, shape, and orientation.
Efficient electrophosphorescent dendrimer LEDs (2003)

Our results show that conjugated dendrimers provide a way of making highly efficient organic LEDs in which the light-emitting layer is deposited from solution. An additional advantage of these dendrimers is that they enable electrophosphorescent devices to be made giving high efficiency at high brightness. Conjugated dendrimers provide a powerful way of taking chromophores and making them solution processible, and are an important new class of material for OLEDs.
Therapeutic Significance of Elevated Tissue Transglutaminase Expression in Pancreatic Cancer (2008)

siRNA-mediated down-regulation of TG2 represents a promising therapeutic approach for improved treatment of PDAC.
An Efficient and Low‐Cost Method for the Purification of Colloidal Nanoparticles (2011)

In null Komma nichts sauber! Ein skalierbares Verfahren zur Reinigung von Nanopartikeln in nichtwässrigen Medien wurde entwickelt, das auf einer reversiblen elektrophoretischen Abscheidung beruht. Damit werden Nanopartikel unterschiedlicher Größe, Form, Zusammensetzung und Ligandenumgebung in weniger als zwei Minuten auf einer Elektrodenoberfläche abgeschieden, gewaschen und redispergiert. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Rapid induction of transcriptional and post-transcriptional gene silencing using a novel Cucumber mosaic virus vector (2006)

We developed a novel RNA virus vector based on the Cucumber mosaic virus (CMV), which is able to efficiently induce gene silencing in plants. We manipulated the RNA 2 of the CMV Y strain, whose genome consists of tripartite components, and introduced restriction sites for cloning a foreign sequence into the vector. To evaluate the vector (designated CMV2-A1) in terms of the ability to induce gene silencing, we cloned portions of the green fluorescent protein (GFP) cDNA or Cauliflower mosaic virus (CaMV) 35S promoter sequences into the vector and inoculated the infectious transcripts into Nicotiana benthamiana plants that express the GFP gene under the control of the CaMV 35S promoter. In both cases, a loss of GFP fluorescence accompanying a reduction in the level of GFP mRNA was induced. The short interfering RNAs (siRNAs) harboring the sequences inserted in the CMV2-A1 vector were detected in the silenced plants. When plants were infected with the virus containing the CaMV 35S promoter sequence, the CaMV 35S promoter sequence in the genomic DNA was heavily methylated. A reduction in the mRNA level of the GFP gene and loss of GFP fluorescence were induced as early as 6 and 12 days post-inoculation, respectively, earlier than the 20 days previously achieved with a Potato virus X vector. These results suggest that the CMV2-A1 vector is suitable for the rapid induction of both transcriptional and post-transcriptional gene silencing.
Grain Oriented Silicon Steel Sheet with TiN Film Characterized by Ultra-low Iron Loss (1994)

An improvement in the iron loss in grain oriented silicon steel sheet was investigated for TiN ceramic coating produced by ion plating on polished silicon steel sheets. The influence of the coating conditions on magnetic properties was also investigated, relating to the thickness, bias voltage, coating temperature, tension, vacuum pressure and reactive N2 gas used for TiN ceramic coating by the hollow cathode discharge (HCD) method.The experimental results obtained are summarized as follows.(1) The magnetic flux density B8(T) of silicon steel sheets with a thin TiN film increases moderately to 0.0040.015T, while the iron loss W17/50 (W/kg) is improved dramatically to 0.11-0.23W/kg.(2) The iron loss in the TiN-coated silicon steel sheet by the HCD method is most improved under the coating conditions of (a) the thickness above 0.7μm, (b) bias voltages in the range of-50 to-100V, (c) coating temperatures in the range of 573 to 673K, (d) tensions in the range of 0.9 to 5MPa, (e) vacuum pressures above 0.3Pa, and (f) reactive N2 gas above 150SCCM.(3) The domain structure of the chemically polished and TiN-coated areas inside a single giant secondary Goss grain changed drastically, showing four to six narrow wall spacings from an original 180° main domain with large black and white wall spacings elongated in the rolling direction.
Occlusive thrombosis in the rabbit auricular vein <i>in vivo</i> targeted by induction of intralumenal cavitation using HIFU and ultrasound contrast agent (2005)

Hypotheses tested: (1) inertial cavitation [IC] could be induced in the venous lumen in vivo by combined use of intravascular microbubble contrast agent and transcutaneous application of 1-MHz high intensity focused ultrasound [HIFU] of very low duty factor, and that IC activity could be detected and quantified in vivo as in earlier in vitro studies via passive cavitation detection methods; (2) robust IC activity would damage the venous endothelium in treated regions; (3) endothelial damage would be proportional to the IC dose developed in the region; (4) severe local endothelial damage alone may be sufficient to induce occlusive thrombosis, or may sensitize the region to low systemic doses of prothrombotic agents, and (5) biologically significant temperature rises and attendant thermal bioeffects in the vessel and perivascular tissues would not occur, even under the highest amplitude acoustic conditions applied. Each hypothesis was supported by the data. The principal result was that under treatment conditions involving very high peak negative acoustic pressures and contrast agent, treated areas thrombosed acutely but non-occlusively. When fibrinogen was administered locally after such treatment, occlusive thrombi formed acutely and only in the treated region, a response observed with none of the other treatments.
Quality monitoring of optical signals influenced by chromatic dispersion in a transmission fiber using averaged Q-factor evaluation (2001)

We evaluated the averaged Q-factor for optical signals distorted by chromatic dispersion in a transmission fiber. This letter confirms that our method has sensitivity to bit error rate degradation due to both the signal-to-noise ratio degradation of pulse distorted signals and pulse distortion itself. It also explains how fault detection in an optical network system can be done with this method.
Chemical Vapor Deposition Growth of Uniform Multilayer Hexagonal Boron Nitride Driven by Structural Transformation of a Metal Thin Film (2020)

Hexagonal boron nitride (h-BN), in particular, multilayer h-BN, has played an important role in the research of two-dimensional materials by enabling the observation of their intrinsic and excellent physical properties via effective screening of the influences from the surrounding environment. However, it is still difficult to synthesize high-quality multilayer h-BN in large scale, and its growth mechanism is not clearly understood. Here, we investigated the chemical vapor deposition (CVD) growth of multilayer h-BN using thin Ni–Fe films that are deposited on sapphire substrates with different crystal planes. The Ni–Fe film on r-plane sapphire was found to produce a uniform multilayer h-BN sheet whose surface coverage is much higher than those on c- and a-plane sapphire. Electron backscatter diffraction and X-ray diffraction investigations revealed that the uniform segregation of multilayer h-BN on Ni–Fe/r-sapphire occurs simultaneously with a drastic structural change of the Ni–Fe thin film from polycrystalline to face-centered cubic (fcc (111)) structure. On the other hand, the Ni–Fe films on c- and a-plane sapphire possessed the fcc (111) structure even before the reaction with borazine feedstock and did not show such structural change. The unique crystallographic change of the Ni–Fe thin film associated with uniform h-BN segregation was further supported by the studies using spinel substrates. Our work indicates the essential role of dynamic evolution of the crystal structure of the thin-film metal catalyst in h-BN growth, highlighting the importance of the controlling crystallographic properties of the metal catalyst for the synthesis of high-quality and uniform multilayer h-BN films.
Progressive Neuromuscular Scoliosis Secondary to Spinal Cord Injury in a Young Patient Treated With Nonfusion Anterior Scoliosis Correction (2019)

Ninety-eight percent of skeletally immature patients with spinal cord injury (SCI) suffer from progressive neuromuscular scoliosis (NMS). Operative treatment has typically been limited to posterior spinal fusion (PSF), but a newer technique as described may be less invasive and preserve more function. A PSF of the entire spine to the pelvis is standard of care. However, maintenance of spinal flexibility, motion, and potential growth is desirable. We present a case for proof-of-concept of utilizing a surgical motion-preserving technique to treat progressive NMS in an 11year-old girl with T10 level (AIS B) paraplegia with a progressive 60° NMS of the lumbar spine. She had anterior scoliosis correction (ASC) from T11-L5 without fusion. Over 24 months, the curve growth-modulated to a residual of 12° with continued modulation to 7° at 3-year follow-up (skeletal maturity).