gebhart/patrepeval huggingface dataset:
Visual search for objects with straight lines (2006)

I present a new method of visual search for objects that include straight lines. This is usually the case for machine-made objects. I describe existing machine vision search methods and show how my method of visual search gives better performance on objects that have straight lines. Inspired from human vision, a two-step process is used. First straight line segments are detected in an image and characterized by their length, midpoint location, and orientation. Second, hypotheses that a particular straight line segment belongs to a known object are generated and tested. The set of hypotheses is constrained by spatial relationships in the known objects. I discuss implementation of my method and its performance and limitations in real and synthetic images. The speed and robustness of my method make it immediately applicable to many machine vision problems.
IGBT modeling for analysis of complicated multi-IGBT Circuits (2009)

A new IGBT (insulated gate bipolar transistor) model for simulation of complicated multi-IGBT circuits is presented. Based on the gate charge and discharge behaviors of IGBT, it piecewise models the turn-on and -off transient of IGBT, and simulates the static characteristics with curve fitting method. With the key features of high simulation speed, easy parameters extraction and clear physical meaning, the model is available for various IGBTs and system level circuits. This paper describes the structure and equivalent circuit of the model in detail, implements it with the simulation tool of PSIM package, and determines the parameters of the model for an IGBT of FF300R12ME3 as an example. The accuracy of the model is verified by the comparison between the simulated and experimental results.
All-fiber RGB Laser Light Source of Head-up Display System for Automobile Application (2020)

We developed an all-fiber RGB laser light source module for application in an automobile head-up display. It is based on laser diodes and an optical fiber combiner that substantially enhances the flexibility of configuration and stability against harsh working conditions for automobiles. We coupled 13 laser diodes with optical fibers and merged them into a single output with a beam combiner device. Red (R), green (G), and blue (B) laser sources were employed to produce primary colors that were mixed into a white light output. An optical output power of approximately 1.5 W was achieved, and the color balance of the output lights was assessed based on the CIE 1931 color space. The optical output power was shown to be stable for over 160 h within an optical fluctuation of less than 0.27%.
ELEVATING MATERNAL INSULIN-LIKE GROWTH FACTOR-I IN MICE AND RATS ALTERS THE PATTERN OF FETAL GROWTH BY REMOVING MATERNAL CONSTRAINT (1992)

Fetal growth is normally constrained by maternal factors. This constraint is demonstrated by the usual inverse linear relationship between litter size and mean fetal weight. Cross-breeding experiments between mice of lines selected for high or low plasma insulin-like growth factor (IGF-I) levels suggested that elevations in maternal IGF-I abolish (P less than 0.01) this constraining effect and reverse the usual positive relationship between fetal and placental size in late gestation. This was confirmed by treating mice and rats throughout pregnancy with IGF-I. In normal mice and in low IGF-I line mice treatment with IGF-I (10 micrograms 8-hourly s.c. from day 1 to 19 of pregnancy) abolished maternal constraint whereas 0.9% (w/v) NaCl treatment did not. In Wistar rats osmotic pumps were implanted to deliver IGF-I (1 microgram/g body weight per day), bovine GH (bGH; 0.6 microgram/g body weight per day) or saline from day 1 to 19 of pregnancy. IGF-I therapy but not bGH or saline abolished (P less than 0.01) maternal constraint and altered (P less than 0.01) the relationship between placental and fetal weight. When high or low IGF-I line mice embroys were transplanted into a normal line of mice, the expected negative relationship (P less than 0.05) between mean fetal weight and litter size was maintained. However, the embryos of the high line were heavier (P less than 0.05) than those from the low line irrespective of fetal number, suggesting a direct role for IGF-I in the regulation of fetal growth.(ABSTRACT TRUNCATED AT 250 WORDS)
Experimental Determinations of Minimum Miscibility Pressures Using Hydrocarbon Gases and CO<sub>2</sub> for Crude Oils from the Bakken and Cut Bank Oil Reservoirs (2020)

Minimum miscibility pressures (MMPs) were measured at reservoir temperatures using a capillary-rise vanishing interfacial tension (VIT) technique for four crude oils collected from different formations in the deep/hot Bakken Petroleum System and the shallow/cool Cut Bank field. Potential injection fluids tested were pure CO2, methane, ethane, propane, and hydrocarbon gas mixtures typical of the rich gas produced from tight shale formations like the Bakken Petroleum System (ca. 7/2/1 mol ratios of methane/ethane/propane). Depending on the oil and test temperature, MMPs were achieved with the fluids in the gas, liquid, or supercritical states. Regardless of the physical state of the test fluids at MMP, propane achieved MMP at the lowest pressure with all four crude oils, followed by ethane, then CO2 and produced gas, and finally methane requiring the highest pressures. For the Bakken (110 °C) and Three Forks crudes (127 °C), MMPs dropped from 29 to 31 MPa with methane from 16.2 to 18.7 MPa with CO2 or produced gas, and further lowered from 9.2 to 10 MPa with ethane, and from 3.8 to 4.3 MPa with propane. Changes in the MMPs with the different fluids were even more dramatic for the Madison and Cut Bank crude oils (both at 28 °C) with methane MMPs about 28–29 MPa, produced gas at 10–10.6 MPa, CO2 at 8.3–8.7 MPa, ethane at 4.2–4.5 MPa, and propane only requiring 1.3–1.4 MPa to achieve MMP. Enriching produced gas by adding either ethane or propane showed approximately linear decreases in the MMPs with the Bakken crude oil. For example, increasing propane in produced gas from 6.7 to 25 mol % reduced the Bakken crude oil’s MMP from 18 to 12.7 MPa, while increasing ethane from 13.5 to 68 mol % reduced the MMP from 18.6 to 11.4 MPa. The results of this experimental study show that injecting produced rich gas may be as effective as injecting CO2 for enhancing oil recovery and that enriching produced gas with ethane or propane may be superior to CO2 for EOR in both shallow/cool and deep/hot reservoirs.
Networks on Chips (2010)

Research on Networks on Chips (NoCs) has spanned over a decade and its results are now visible in some products. Thus the seminal idea of using networking technology to address the chip-level interconnect problem has been shown to be correct. Moreover, as technology scales down in geometry and chips scale up in complexity, NoCs become the essential element to achieve the desired levels of performance and quality of service while curbing power consumption levels. Design and timing closure can only be achieved by a sophisticated set of tools that address NoC synthesis, optimization and validation.
Measurment Of Residual Stress In Ferromagnetic Materials (1992)

Magnetoacoustic (MAC) and magnetoacoustic emission (MAE) techniques combined to provide complete characterization of residual stresses in ferromagnetic structural materials. Combination of MAC and MAE techniques makes it possible to characterize residual tension and compression without being limited by surface conditions and unavailability of calibration standards. Significant in field of characterization of materials as well as detection of fatigue failure.
Imprint lithography template technology for bit patterned media (BPM) (2011)

Bit patterned media (BPM) for magnetic recording has emerged as a promising technology to deliver thermally stable magnetic storage at densities beyond 1Tb/in<sup>2</sup>. Insertion of BPM into hard disk drives will require the introduction of nanoimprint lithography and other nanofabrication processes for the first time. In this work, we focus on nanoimprint and nanofabrication challenges that are being overcome in order to produce patterned media. Patterned media has created the need for new tools and processes, such as an advanced rotary e-beam lithography tool and block copolymer integration. The integration of block copolymer is through the use of a chemical contrast pattern on the substrate which guides the alignment of di-block copolymers. Most of the work on directed self assembly for patterned media applications has, until recently, concentrated on the formation of circular dot patterns in a hexagonal close packed lattice. However, interactions between the read head and media favor a bit aspect ratio (BAR) greater than one. This design constraint has motivated new approaches for using self-assembly to create suitable high-BAR master patterns and has implications for template fabrication.
Three Efficient Methods for Preparation of Coelenterazine Analogues (2016)

The growing popularity of bioluminescent assays has highlighted the need for coelenterazine analogues possessing properties tuned for specific applications. However, the structural diversity of known coelenterazine analogues has been limited by current syntheses. Known routes for the preparation of coelenterazine analogues employ harsh reaction conditions that limit access to many substituents and functional groups. Novel synthetic routes reported here establish simple and robust methods for synthesis and investigation of structurally diverse marine luciferase substrates. Specifically, these new routes allow synthesis of coelenterazine analogues containing various heterocyclic motifs and substituted aromatic groups with diverse electronic substituents at the R(2) position. Interesting analogues described herein were characterized by their physicochemical properties, bioluminescent half-life, light output, polarity and cytotoxicity. Some of the analogues represent leads that can be utilized in the development of improved bioluminescent systems.
HIL (2013)

We introduce HIL, a high-level scripting language for entity resolution and integration. HIL aims at providing the core logic for complex data processing flows that aggregate facts from large collections of structured or unstructured data into clean, unified entities. Such flows typically include many stages of processing that start from the outcome of information extraction and continue with entity resolution, mapping and fusion. A HIL program captures the overall integration flow through a combination of SQL-like rules that link, map, fuse and aggregate entities. A salient feature of HIL is the use of logical indexes in its data model to facilitate the modular construction and aggregation of complex entities. Another feature is the presence of a flexible, open type system that allows HIL to handle input data that is irregular, sparse or partially known.
Stress-testing the relationship between T cell receptor/peptide-MHC affinity and cross-reactivity using peptide velcro (2018)

T cell receptors (TCRs) bind to peptide-major histocompatibility complex (pMHC) with low affinity (<i>K</i><sub>d</sub> ∼ μM), which is generally assumed to facilitate cross-reactive TCR "scanning" of ligands. To understand the relationship between TCR/pMHC affinity and cross-reactivity, we sought to engineer an additional weak interaction, termed "velcro," between the TCR and pMHC to probe the specificities of TCRs at relatively low and high affinities. This additional interaction was generated through an eight-amino acid peptide library covalently linked to the N terminus of the MHC-bound peptide. Velcro was selected through an affinity-based isolation and was subsequently shown to enhance the cognate TCR/pMHC affinity in a peptide-dependent manner by ∼10-fold. This was sufficient to convert a nonstimulatory ultra-low-affinity ligand into a stimulatory ligand. An X-ray crystallographic structure revealed how velcro interacts with the TCR. To probe TCR cross-reactivity, we screened TCRs against yeast-displayed pMHC libraries with and without velcro, and found that the peptide cross-reactivity profiles of low-affinity (<i>K</i><sub>d</sub> > 100 μM) and high-affinity (<i>K</i><sub>d</sub> ∼ μM) TCR/pMHC interactions are remarkably similar. The conservation of recognition of the TCR for pMHC across affinities reveals the nature of low-affinity ligands for which there are important biological functions and has implications for understanding the specificities of affinity-matured TCRs.
Exploiting frequency-scaling invariance properties of the scale transform for automatic speech recognition (2000)

An experimental study of the application of scale-transform to improve the performance of speaker independent continuous speech recognition, is presented in this paper. Three major results are described. First, a comparison was made between the scale-transform based magnitude cepstrum coefficients (STCC) and mel-scale filter bank cepstrum coefficients (MFCC) on a telephone based connected digit recognition task. It was shown that the STCC can obtain a performance that is close to that of the MFCC. Second, a simple frequency-normalization procedure was applied to the scale-transform representation that improved performance on the connected digit recognition task with respect to the MFCC. Finally, in a more controlled experimental setting using the TIMIT database, it was shown that the application of phone-specific frequency warpings improved phone classification performance over using a single speaker-specific warping. This last result may have general implications for all frequency warping based speaker normalization procedures.
Knowledge-Based Condition Survey Inspection Concepts (2007)

The U.S. Army’s Engineer Research and Development Center—Construction Engineering Research Laboratory has developed a “knowledge-based” approach to planning and conducting routine facility inspections. Rather than simply recording deficiencies on a calendar-based schedule this new approach uses knowledge of facilities to develop and execute a tailored inspection plan for individually defined facility “management units.” This knowledge includes measurable attributes such as facility importance, management unit importance, condition (past, present, and predicted future), desired condition thresholds, and expected asset remaining life. Also, recognizing that there are several inspection objectives to be met at different times in a management unit life cycle, different levels of inspections may be used at different times to attain those objectives. The “knowledge-based condition survey inspection (KBCSI)” approach marries all of these elements together to develop inspection plans for a vast array of facility components. The result is more meaningful facility inspection information with less inspection effort compared to traditional calendar-based inspection approaches. This paper discusses the KBCSI approach as applied to building component life cycle management.
Session guarantees for weakly consistent replicated data (2002)

Four per-session guarantees are proposed to aid users and applications of weakly consistent replicated data: "read your writes", "monotonic reads", "writes follow reads", and "monotonic writes". The intent is to present individual applications with a view of the database that is consistent with their own actions, even if they read and write from various, potentially inconsistent servers. The guarantees can be layered on existing systems that employ a read-any/write-any replication scheme while retaining the principal benefits of such a scheme, namely high availability, simplicity, scalability, and support for disconnected operation. These session guarantees were developed in the context of the Bayou project at Xerox PARC in which we are designing and building a replicated storage system to support the needs of mobile computing users who may be only intermittently connected.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Role of Smad7 in inflammatory bowel diseases (2012)

Crohn's disease and ulcerative colitis, the major forms of inflammatory bowel diseases (IBD) in man, are complex diseases in which genetic and environmental factors interact to promote an excessive mucosal immune response directed against normal components of the bacterial microflora. There is also evidence that the pathologic process is due to defects in counter-regulatory mechanisms, such as those involving the immunosuppressive cytokine transforming growth factor (TGF)-β1. Indeed, studies in human IBD tissues and murine models of colitis have documented a disruption of TGF-β1 signalling marked by a block in the phosphorylation of Smad3, a signalling molecule associated with the activated TGF-β receptor, due to up-regulation of Smad7, an intracellular inhibitor of Smad3 phosphorylation. Knock-down of Smad7 with a specific antisense oligonucleotide restores TGF-β1/Smad3 signalling, thus resulting in a marked suppression of inflammatory cytokine production and attenuation of murine colitis. These findings together with the demonstration that Smad7 antisense oligonucleotide is not toxic when administered in mice have paved the way for the development of a Smad7 antisense oligonucleotide-based pharmaceutical compound that is now ready to enter the clinics. In this article we review the available data supporting the pathogenic role of Smad7 in IBD and discuss whether and how Smad7 antisense therapy could help dampen the ongoing inflammation in IBD.
Laser-Induced Photofragmentation/Photoionization Spectrometry: A Method for Detecting Ambient Oxides of Nitrogen (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTLaser-Induced Photofragmentation/Photoionization Spectrometry: A Method for Detecting Ambient Oxides of NitrogenJ. B. Simeonsson, G. W. Lemire, and R. C. SausaCite this: Anal. Chem. 1994, 66, 14, 2272–2278Publication Date (Print):July 1, 1994Publication History Published online1 May 2002Published inissue 1 July 1994https://pubs.acs.org/doi/10.1021/ac00086a012https://doi.org/10.1021/ac00086a012research-articleACS PublicationsRequest reuse permissionsArticle Views157Altmetric-Citations27LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Transition-Metal Additives For Long-Life Na/NiCI(2) Cells (1995)

Transition-metal additives in cathodes of Na/NiCI(2) high-temperature, rechargeable electrochemical cells found to slow premature fading of charge/discharge capacity. Decline in capacity of cell attributed to agglomeration of Ni particles at cathode: this agglomeration reduces electrochemical area of cathode. Depending on choice of transition-metal additive for particular cell, additive might even participate in desired electrochemical reactions in cell, contributing to specific energy of cell.
Scalable clustering of news search results (2011)

In this paper, we present a system for clustering the search results of a news search engine. The news search interface includes the relevant news articles to a given query organized in terms of related news stories. Here each cluster corresponds to a news story and the news articles are clustered into stories. We present a system that clusters the search results of a news search system in a fast and scalable manner. The clustering system is organized into three components including offline clustering, incremental clustering and realtime clustering. We propose novel techniques for clustering the search results in realtime. The experimental results with large collections of news documents reveal that our system is both scalable and also achieves good accuracy in clustering the news search results.
Universal discrete denoising (2003)

We propose a discrete denoising algorithm, that, based on the observation of the output of a known discrete memoryless channel (DMC), estimates the input sequence to minimize a given fidelity criterion. The algorithm is universal in the sense that it requires no knowledge of the input sequence or its statistical properties. Yet, asymptotically it performs as well as the optimum denoiser that knows the input sequence distribution. The proposed denoising algorithm is practical, and can be implemented in O(n log n) time and O(n/sup 2/3/ log n) storage complexity. Extensions to the case of delay-constrained denoising, and to the case of channel uncertainty, are briefly discussed.
Catalytic transfer hydrogenation of ethyl levulinate to γ-valerolactone over zirconium-based metal–organic frameworks (2016)

A series of zirconium-based MOFs with different ligand functionalities and porosities were applied for catalytic transfer hydrogenation of ethyl levulinate to form γ-valerolactone, using isopropanol as a hydrogen donor.
Bioelectronic Sensing of Insulin Demand (2011)

This chapter contains sections titled: Sensor Technologies and Cell Therapy in Diabetes: a Life-Long Debilitating Disease The Biological Sensor: Function of β-Cells and Islet Automated Islet Screening and Bioelectronic Sensor of Insulin Demand Closed Loop Exploration In Vitro Methods Results Conclusions References
Using Haloarcula marismortui Bacteriorhodopsin as a Fusion Tag for Enhancing and Visible Expression of Integral Membrane Proteins in Escherichia coli (2013)

Membrane proteins are key targets for pharmacological intervention because of their vital functions. Structural and functional studies of membrane proteins have been severely hampered because of the difficulties in producing sufficient quantities of properly folded and biologically active proteins. Here we generate a high-level expression system of integral membrane proteins in Escherichia coli by using a mutated bacteriorhodopsin (BR) from Haloarcula marismortui (HmBRI/D94N) as a fusion partner. A purification strategy was designed by incorporating a His-tag on the target membrane protein for affinity purification and an appropriate protease cleavage site to generate the final products. The fusion system can be used to detect the intended target membrane proteins during overexpression and purification either with the naked eye or by directly monitoring their characteristic optical absorption. In this study, we applied this approach to produce two functional integral membrane proteins, undecaprenyl pyrophosphate phosphatase and carnitine/butyrobetaine antiporter with significant yield enhancement. This technology could facilitate the development of a high-throughput strategy to screen for conditions that improve the yield of correctly folded target membrane proteins. Other robust BRs can also be incorporated in this system.