gebhart/patrepeval huggingface dataset:
Investigation of bovine ubiquitin conformers separated by high-field asymmetric waveform ion mobility spectrometry: Cross section measurements using energy-loss experiments with a triple quadrupole mass spectrometer (2000)

High-field asymmetric waveform ion mobility spectrometry (FAIMS) was used to separate gas-phase conformers of bovine ubiquitin produced by electrospray ionization. These conformers were sampled by a triple quadrupole mass spectrometer where energy-loss experiments, following the work of Douglas and co-workers, were used to determine their cross sections. The measured cross sections for some conformers were readily altered by the voltages applied to the interface ion optics, therefore very gentle mass spectrometer interface conditions were required to preserve gas-phase conformers separated by FAIMS. Cross sections for 19 conformers (charge states +5 through +13) were measured. Two conformers for the +12 charge state, which were readily separated in FAIMS, were found to have similar cross sections. Based on a method to calibrate the collision gas thickness, the cross sections measured using the FAIMS/energy-loss method were compared with literature values determined using drift tube ion mobility spectrometry. The comparison illustrated that the conformers of bovine ubiquitin that were identified using drift tube ion mobility spectrometry were also observed using the FAIMS device.
In Situ Growth of ZnO Nanocrystals from Solid Electrospun Nanofiber Matrixes (2006)

Porous fiber membranes consisting of 1D assemblies of ZnO nanocrystal-supported poly(vinyl alcohol) (PVA) nanofibers are described. These hybrid nanofiber membranes were assembled by first electrospinning a ZnO precursor-containing PVA aqueous solution. Subsequently, the electrospun composite nanofibers were submerged in a basic ethanol solution. As a result, ZnO precursors in solid PVA matrixes were hydrolyzed to generate ZnO crystals residing on the fiber surfaces. Photoluminescence spectroscopy analysis demonstrated the as-hydrolyzed fiber membranes possess white luminescence. Furthermore, the ZnO-encapsulated PVA nanofibers were prepared by directly electrospinning a ZnO nanocrystal-containing PVA solution as the contrast of the as-hydrolyzed hybrid nanofibers. The surface photovoltage spectroscopy (SPS) confirmed that the as-hydrolyzed hybrid fiber membranes had a strong SPS response, but the directly spun fiber membranes did not have any SPS response. This can be attributed to the favorable structure of the hydrolyzed hybrid nanofibers, that is, the surface residence of ZnO permits ZnO crystals to make direct contact with ITO electrodes to transfer the photogenerated electron originating from ZnO to ITO electrodes. By contrast, the transfer of the photogenerated electron is limited by PVA matrixes in the directly spun fiber system.
BAW radiation from LSAW resonators on lithium tantalate (2002)

We report the first direct measurements of bulk-acoustic waves radiated by a leaky SAW resonator on 36/spl deg/YX-LiTaO/sub 3/. The BAW radiation patterns on the backside of the piezoelectric substrate were measured with the help of a scanning laser interferometer probe. The different energy-flow angles into the substrate were obtained as functions of frequency and then used to identify the corresponding bulkwave modes arriving to the substrate bottom. The measured energy-flow angles at different frequencies along with the simulated are reported. In addition, the reflected BAW radiation arriving to the top of the substrate was detected.
Prednisolone Treatment of Respiratory Syncytial Virus Infection: A Randomized Controlled Trial of 147 Infants (1999)

Our randomized prospective study in infants hospitalized with acute RSV infection showed no effect of systemic prednisolone treatment either in the acute state of RSV infection, nor in the follow-up 1 month and 1 year after admission to hospital. We find our results in agreement with the largest studies reported earlier; therefore, corticosteroid, whether by the systemic route or by inhalation, should not be prescribed to infants with RSV infection.
Conjugal transfer of a shuttle vector from the human colonic anaerobe Bacteroides uniformis to the ruminal anaerobe Prevotella (Bacteroides) ruminicola B(1)4 (1991)

Prevotella ruminicola (formerly Bacteroides ruminicola) is an anaerobic, gram-negative, polysaccharide-degrading bacterium which is found in the rumina of cattle. Since P. ruminicola is thought to make an important contribution to digestion of plant material in rumina, the ability to alter this strain genetically might help improve the efficiency of rumen fermentation. However, previously there has been no way to introduce foreign DNA into P. ruminicola strains. In this study we transferred a shuttle vector, pRDB5, from the colonic species Bacteroides uniformis to P. ruminicola B(1)4. The transfer frequency was 10(-6) to 10(-7) per recipient. pRDB5 contains sequences from pBR328, a cryptic colonic Bacteroides plasmid pB8-51, and a colonic Bacteroides tetracycline resistance (Tcr) gene. pRDB5 was mobilized out of B. uniformis by a self-transmissible Bacteroides chromosomal element designated Tcr Emr 12256. pRDB5 replicated in Escherichia coli as well as in Bacteroides spp. and was also mobilized from E. coli to B. uniformis by using IncP plasmid R751. However, direct transfer from E. coli to P. ruminicola B(1)4 was not detected. Thus, to introduce cloned DNA into P. ruminicola B(1)4, it was necessary first to mobilize the plasmid from E. coli to B. uniformis and then to mobilize the plasmid from B. uniformis to P. ruminicola B(1)4.
Neural and Oligodendrocyte Progenitor Cells: Transferrin Effects on Cell Proliferation (2013)

NSC (neural stem cells)/NPC (neural progenitor cells) are multipotent and self-renew throughout adulthood in the SVZ (subventricular zone) of the mammalian CNS (central nervous system). These cells are considered interesting targets for CNS neurodegenerative disorder cell therapies, and understanding their behaviour in vitro is crucial if they are to be cultured prior to transplantation. We cultured the SVZ tissue belonging to newborn rats under the form of NS (neurospheres) to evaluate the effects of Tf (transferrin) on cell proliferation. The NS were heterogeneous in terms of the NSC/NPC markers GFAP (glial fibrillary acidic protein), Nestin and Sox2 and the OL (oligodendrocyte) progenitor markers NG2 (nerve/glia antigen 2) and PDGFRα (platelet-derived growth factor receptor α). The results of this study indicate that aTf (apoTransferrin) is able to increase cell proliferation of SVZ-derived cells in vitro, and that these effects were mediated at least in part by the TfRc1 (Tf receptor 1). Since OPCs (oligodendrocyte progenitor cells) represent a significant proportion of the proliferating cells in the SVZ-derived primary cultures, we used the immature OL cell line N20.1 to show that Tf was able to augment the proliferation rate of OPC, either by adding aTf to the culture medium or by overexpressing rat Tf in situ. The culture medium supplemented with ferric iron, together with aTf, increased the DNA content, while ferrous iron did not. The present work provides data that could have a potential application in human cell replacement therapies for neurodegenerative disease and/or CNS injury that require the use of in vitro amplified NPCs.
Inhibition of starch synthesis results in overproduction of lipids in <i>Chlamydomonas reinhardtii</i> (2010)

Starch and neutral lipids are two major carbon storage compounds in many microalgae and plants. Lipids are more energy rich and have often been used as food and fuel feedstocks. Genetic engineering of the lipid biosynthesis pathway to overproduce lipid has achieved only limited success. We hypothesize that through blocking the competing pathway to produce starch, overproduction of neutral lipid may be achieved. This hypothesis was tested using the green microalga Chlamydomonas reinhardtii and its low starch and starchless mutants. We discovered that a dramatic increase in neutral lipid content and the neutral lipid/total lipid ratio occurred among the mutants under high light and nitrogen starvation. BAFJ5, one of the mutants defective in the small subunit of ADP-glucose pyrophosphorylase, accumulated neutral and total lipid of up to 32.6% and 46.4% of dry weight (DW) or 8- and 3.5-fold higher, respectively, than the wild-type. These results confirmed the feasibility of increasing lipid production through redirecting photosynthetically assimilated carbon away from starch synthesis to neutral lipid synthesis. However, some growth impairment was observed in the low starch and starchless mutants, possibly due to altered energy partitioning in PSII, with more excitation energy dissipated as heat and less to photochemical conversion. This study demonstrated that biomass and lipid production by the selected mutants can be improved by physiological manipulation.
Coginitve Task Analysis of Distributed Network-Centric Information for the Promotion of Shared Situational Awareness Within Collaborative UAS Operations (2009)

A hybrid model of cognitive task analysis coupled with activity theory and team cognition was evaluated to determine human-computer interface (HCI) design factors that promote Shared Situational Awareness (SSA) within a collaborative unmanned aerial system (UAS). A computer testbed simulation was created for use with participants in a time-sensitive Intelligence, Surveillance, and Reconnaissance (ISR) and weapons engagement mission testing scenario. A cognitive analysis was performed which consisted of a Hierarchical Task Analysis (HTA), Applied Cognitive Task Analysis (ACTA), time-sensitive activity analysis, and coordinated team cognition. Results from testing indicated that the promotion of situational awareness (SA) was enabled by network-centric updates among users in a collaborative UAS. The major cognitive task determined was maintaining SA of the big picture while performing the mission task at hand. Recommendations include the automation of a region of interest for network-centric updates, active filters for decluttering, and the synchronization of entities portrayed on HCIs.
[Psychological basis for self-regulation of behavior in sailors drafted into military service]. (2003)

Valuable-and-semantic spheres of Navy servicemen called-up for military service were investigated. For the servicemen with "psychical discomfort" the behavior "disadaptation" strategy is characteristic: the unrealistic orientation towards the freedom and material security; the problem of difficult choice between the interest in unofficial contact and the necessity to defer to rank; the "internal vacuum" state connected with little value of cognitive orientations and their relative accessibility, and on the contrary, the "internal conflict" state conditioned by the inaccessibility of vital and social values. The most of investigated persons are not oriented towards the highest levels of behavior self-regulation that are connected with the search for sense and choice freedom. They are characterized by the regulation lowest levels connected with stereotype and comfort in observing the social standards (the group of "relative" psychical comfort) or by the non-adequate ways of behavior self-regulation that aggravate the disadaptation, morbidity and person's deformation (the group of "psychical discomfort").
Enterprise agility: a view from the PRISM lab (1999)

The agility of enterprises is analyzed in this article from two perspectives: business and organizational agility, and operational and logistics agility. Because of the powerful support of information technologies, mainly AI and networking, companies can seek collaborators to accomplish complex customers’ requirements without investing to expand their own capacity. The emerging alliances of enterprises are virtually formed for various customers’ and markets’ needs. This concept sustains business and organizational agility. In terms of operational and logistics agility, this article suggests that the connection between the autonomy functions and agility requires further study. Our research has proposed that error detection and recovery, and conflict resolution are two significant functions of operational and logistics agility, and determine the expected benefits from the business and organizational agility. The link between a given enterprise flexibility and agility is also analyzed.
A marching voxels method for surface rendering of volume data (2002)

The marching cubes method is a well-known surface extraction method by using the surface configurations of cubes for surface rendering of volume data. The marching cubes method has three main disadvantages: it is time consuming, ambiguous, and holes are generated. All these disadvantages come from the use of the surface configurations of cubes. We propose an efficient surface extraction method, the marching voxels method, for surface rendering of volume data. Instead of using the surface configurations of cubes, the marching voxels method first generates triangles for inner voxels. Then it combines the triangles of inner voxels to produce the surface of an object. Finally, the surface of an object is projected to a plane to form the final image. Since the marching voxels method considers the combination of triangles of voxels not cubes and the combination of triangles is performed in a deterministic way, there is neither ambiguous case of a combination nor holes for the generated surface. The experimental results show that the marching voxels method saves about 30% of the surface rendering time compared to the marching cubes method for test samples.
Prevalence of Co-Infections with Respiratory Viruses in Individuals Investigated for SARS-CoV-2 in Ontario, Canada (2021)

Findings of this study may not support routine testing for seasonal respiratory viruses among all individuals tested for SARS-CoV-2, as they were rare during the study period nor associated with severe disease. However, testing for seasonal respiratory viruses should be performed in severely ill individuals, in which detection of other viruses may assist with patient management.
High-Power Ultralow-Chirp 10-Gb/s Electroabsorption Modulator Integrated Laser With Ultrashort Photocarrier Lifetime (2006)

A high-power, ultralow-chirp electroabsorption modulator (EAM) integrated with a distributed-feedback laser diode (EML) having ultrashort lifetime of photogenerated holes in the EAM quantum-well (QW) structure is reported for the first time. A shallow QW structure having a small valence band offset to enhance the sweepout of photogenerated holes was employed as EAM absorption layer. The measured hole lifetimes were 7-11 ps, and the measured frequency chirp (/spl alpha/-parameter) was low or negative at low EAM reverse bias voltages even under high optical output power conditions. Successful 10-Gb/s 80-km normal-dispersion single-mode fiber transmission (chromatic dispersion D=1600 ps/nm) and the record average fiber optical output power (P/sub f/) of +5.3 dBm were achieved at 25/spl deg/C. In addition, semicooled operation of EML at enhanced bit rates has been demonstrated for application in small-form-factor protocol-agnostic optical transceivers. A 10.7-Gb/s 1600-ps/nm transmission was achieved at 45/spl deg/C and P/sub f/=+3.0 dBm.
Dynamic Models and Model Validation for PEM Fuel Cells Using Electrical Circuits (2005)

This paper presents the development of dynamic models for proton exchange membrane (PEM) fuel cells using electrical circuits. The models have been implemented in MATLAB/SIMULINK and PSPICE environments. Both the double-layer charging effect and the thermodynamic characteristic inside the fuel cell are included in the models. The model responses obtained at steady-state and transient conditions are validated by experimental data measured from an Avista Labs SR-12 500-W PEM fuel-cell stack. The models could be used in PEM fuel-cell control related studies.
Effect of leavening microflora on pizza dough properties (1998)

Fourteen different starter cultures containing one strain of Saccharomyces cerevisiae with and without individual or combinations of lactic acid bacteria (Lactobacillus plantarum, Lact. sanfrancisco, Enterococcus faecium, Leuconostoc mesenteroides) were employed to investigate the role of leavening microflora on the properties of pizza doughs. Microbiological, chemical and physical characteristics of doughs prepared with the same flour and under the same processing conditions were determined. Leavening times and acidification properties depended on the microbial association used. The proportions of lactic and acetic acid produced by lactic acid bacteria were consistent with the metabolic properties of the strains employed. The bacteria/yeast ratios arising from microbial counts at the end of the leavening process were always lower in comparison to sour- or bread-doughs. The size of the yeast population did not change much, while bacteria showed from one to four duplications. Rheologically, the fermented doughs could only be significantly distinguished from the control dough with regard to the elastic modulus. Principal Component Analysis was applied to the acidimetric data. The scattergram of the two principal components effectively discriminated 13 of the 14 pizza dough types.
Evolving role definitions through permission invocation patterns (2013)

In role-based access control (RBAC), roles are traditionally defined as sets of permissions. Roles specified by administrators may be inaccurate, however, such that data mining methods have been proposed to learn roles from actual permission utilization. These methods minimize variation from an information theoretic perspective, but they neglect the expert knowledge of administrators. In this paper, we propose a strategy to enable a controlled evolution of RBAC based on utilization. To accomplish this goal, we extend a subset enumeration framework to search candidate roles for an RBAC model that addresses an objective function which balances administrator beliefs and permission utilization. The rate of role evolution is controlled by an administrator-specified parameter. To assess effectiveness, we perform an empirical analysis using simulations, as well as a real world dataset from an electronic medical record system (EMR) in use at a large academic medical center (over 8000 users, 140 roles, and 140 permissions). We compare the results with several state-of-the-art role mining algorithms using 1) an outlier detection method on the new roles to evaluate the homogeneity of their behavior and 2)a set-based similarity measure between the original and new roles. The results illustrate our method is comparable to the state-of-the-art, but allows for a range of RBAC models which tradeoff user behavior and administrator expectations. For instance, in the EMR dataset, we find the resulting RBAC model contains 22% outliers and a distance of 0.02 to the original RBAC model when the system is biased toward administrator belief, and 13% outliers and a distance of 0.26 to the original RBAC model when biased toward permission utilization.
Temporal Resolution Multiplexing: Exploiting the limitations of spatio-temporal vision for more efficient VR rendering (2019)

Rendering in virtual reality (VR) requires substantial computational power to generate 90 frames per second at high resolution with good-quality antialiasing. The video data sent to a VR headset requires high bandwidth, achievable only on dedicated links. In this paper we explain how rendering requirements and transmission bandwidth can be reduced using a conceptually simple technique that integrates well with existing rendering pipelines. Every even-numbered frame is rendered at a lower resolution, and every odd-numbered frame is kept at high resolution but is modified in order to compensate for the previous loss of high spatial frequencies. When the frames are seen at a high frame rate, they are fused and perceived as high-resolution and high-frame-rate animation. The technique relies on the limited ability of the visual system to perceive high spatio-temporal frequencies. Despite its conceptual simplicity, correct execution of the technique requires a number of non-trivial steps: display photometric temporal response must be modeled, flicker and motion artifacts must be avoided, and the generated signal must not exceed the dynamic range of the display. Our experiments, performed on a high-frame-rate LCD monitor and OLED-based VR headsets, explore the parameter space of the proposed technique and demonstrate that its perceived quality is indistinguishable from full-resolution rendering. The technique is an attractive alternative to reprojection and resolution reduction of all frames.
A balanced optical heterodyne detection for local-oscillator excess-noise suppression (2012)

A semiclassical approach is used to calculate the principle for heterodyne detection utilizing two optical detectors. These calculations show that excess-noise in the local-oscillator can be canceled and the balanced-detector optical heterodyne detection requires less local oscillator power compared with the traditional single-detector optical heterodyne detection. An experimental demonstration of excess-noise cancellation is reported.
Where to Kill the Cyber Kill-Chain: An Ontology-Driven Framework for IoT Security Analytics (2016)

In this paper we propose an ontology-based framework for the Internet of Things (IoT) to safeguard against Advanced Persistent Threats (APTs). The framework grasps the understanding of attack kill-chain, leveraged attack patterns and vulnerabilities and aligns them with network semantics to gauge their applicability on IoT systems. Followed by that, it automatically infers efficient solutions for changing attack tactics by performing cost-benefit analysis of viable countermeasures through rule-based ontology reasoning. Our work leverages existing ontologies of well-known Cyber Threat Intelligence (CTI) standards by extending them with new concepts and aligning with a novel IoT ontology. The framework automatically extracts relevant information from XML-based threat feeds, populates it as ontology instances and maps it with IoT configurations to perform the desired reasoning. The practicality of approach has been illustrated by evaluating a sample IoT network against a variety of real-world APTs.
Report to Congress: Mandatory Minimum Penalties in the Federal Criminal Justice System (2012)

Research Article| February 01 2012 Report to Congress: Mandatory Minimum Penalties in the Federal Criminal Justice System United States Sentencing Commission (October 2011) United States Sentencing Commission (October 2011) Search for other works by this author on: This Site PubMed Google Scholar Federal Sentencing Reporter (2012) 24 (3): 185–192. https://doi.org/10.1525/fsr.2012.24.3.185 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation United States Sentencing Commission (October 2011); Report to Congress: Mandatory Minimum Penalties in the Federal Criminal Justice System. Federal Sentencing Reporter 1 February 2012; 24 (3): 185–192. doi: https://doi.org/10.1525/fsr.2012.24.3.185 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search nav search search input Search input auto suggest search filter All ContentFederal Sentencing Reporter Search This content is only available via PDF. © 2012 Vera Institute of Justice. All rights reserved. Please direct requests for permission to photocopy or reproduce article content through the University of California Press's Rights and Permissions website, http://www.ucpressjournals.com/reprintInfo.asp.2012 Article PDF first page preview Close Modal You do not currently have access to this content.