gebhart/patrepeval huggingface dataset:
Multimedia ontology learning for automatic annotation and video browsing (2008)

In this work, we offer an approach to combine standard multimedia analysis techniques with knowledge drawn from conceptual metadata provided by domain experts of a specialized scholarly domain, to learn a domain-specific multimedia ontology from a set of annotated examples. A standard Bayesian network learning algorithm that learns structure and parameters of a Bayesian network is extended to include media observables in the learning. An expert group provides domain knowledge to construct a basic ontology of the domain as well as to annotate a set of training videos. These annotations help derive the associations between high-level semantic concepts of the domain and low-level MPEG-7 based features representing audio-visual content of the videos. We construct a more robust and refined version of this ontology by learning from this set of conceptually annotated videos. To encode this knowledge, we use MOWL, a multimedia extension of Web Ontology Language (OWL) which is capable of describing domain concepts in terms of their media properties and of capturing the inherent uncertainties involved. We use the ontology specified knowledge for recognizing concepts relevant to a video to annotate fresh addition to the video database with relevant concepts in the ontology. These conceptual annotations are used to create hyperlinks in the video collection, to provide an effective video browsing interface to the user.
Optical properties across the insulator to metal transitions in vanadium oxide compounds (2009)

We review the optical properties of three vanadium oxide compounds V(2)O(3), VO(2) and V(3)O(5), belonging to the so-called Magnéli phase. Their electrodynamics across a metal to insulator transition is investigated as a function of both temperature and pressure. We analyse thoroughly the optical results, with a special emphasis on the infrared spectral weight. This allows us to discuss the nature of the mechanisms driving the phase transitions in the three compounds, pointing out the role of electron-electron and electron-phonon interactions in the various cases.
Monoclonal antibodies to <i>Salmonella</i> lipopolysaccharide: anti-O-polysaccharide antibodies protect C3H mice against challenge with virulent <i>Salmonella typhimurium</i>. (1984)

The present investigation reports the production of monoclonal antibodies to antigenic determinants of the O-polysaccharide of Salmonella typhimurium lipopolysaccharide (LPS), and assesses the effectiveness of these antibodies in protecting C3H mice against the lethal effects of Salmonella infection. Hybridomas were generated by fusing spleen cells from (BALB/c X A/J)F1 (CAF1) mice hyperimmunized by i.v. injection with acetone-killed S. typhimurium SR-11 with X63-Ag8.653 murine myeloma cells. Hybridomas producing antibodies reactive with S. typhimurium SR-11 whole cells were subcloned, and seven of the resulting clones as well as one previously described clone were selected for use in the studies reported here. Monoclonal antibodies from these eight clones were of the IgG1 (1), IgG3 (6), or IgM (1) isotype and were specific for the O-polysaccharide region of Salmonella LPS, reacting with LPS from smooth S. typhimurium SR-11 and LT-2, but not with LPS from rough S. minnesota R60 (Ra), R345 (Rb), or R595 (Re). The effectiveness of each monoclonal antibody in protecting C3H/HeN and C3H/HeJ mice against the lethal effects of Salmonella infection was evaluated by comparing the median length of survival of groups of mice given antibody by i.p. injection before i.p. challenge with virulent S. typhimurium SR-11 to that of animals that received no antibody. Three out of eight monoclonal anti-O-polysaccharide antibodies, ST-1 (IgM), 10-5-47 (IgG3), and 10-5-6 (IgG3), provided significant (p less than 0.01) protection to C3H/HeN mice challenged with approximately 10(4) LD100 of Salmonella. Only antibodies ST-1 and 10-5-6, however, extended the median length of survival of C3H/HeJ mice beyond that of infected controls. Mouse antiserum prepared against S. typhimurium SR-11 was equally protective in C3H/HeJ mice. In an attempt to understand the contribution of antibody specificity to the relative differences in the protective capacities of the monoclonal antibodies, their reactivities with several Salmonella reference strains of different classical serotypes were examined. Although some differences in reactivity against the different strains were apparent, this approach was not adequate for defining the fine specificity of these monoclonal antibodies. The results of this study provide evidence that monoclonal antibodies with specificity to the O-polysaccharide region of Salmonella LPS can protect C3H mice against challenge with the homologous bacterial strain.
Caffeine dissociates complexes between DNA and intercalating dyes: Application for bleaching fluorochrome‐stained cells for their subsequent restaining and analysis by laser scanning cytometry (2001)

Background Removal of the nucleic acid-bound fluorochrome is desirable when stained cells have to be reanalyzed using other fluorochromes. It is also often desirable to remove DNA-bound antitumor drugs from drug-treated cells, to improve cell staining. We have previously observed that in aqueous solutions, the methylxanthine caffeine (CFN) decreases interactions between planar aromatic molecules such as intercalating dyes or antitumor drugs and nucleic acids. The aim of this study was to explore whether this property of CFN can be utilized to remove the DNA-bound intercalating dyes propidium iodide (PI) or 7-aminoactinomycin D (7-AAD) from the cells and whether the bleached cells can be restained and reanalyzed. Methods HL-60 cells were fixed in 70% ethanol and their DNA was stained with PI or 7-AAD. The cells were then rinsed with a 0.05 M solution of CFN in phosphate-buffered saline (PBS) or with PBS alone. The decrease in intensity of cell fluorescence during rinsing was measured by laser scanning cytometry (LSC) to obtain the bleaching kinetics of individual cells. The bleached cells were then restained with PI, 7-AAD, or the protein-specific fluorochrome sulforhodamine 101(S101). Their fluorescence was measured again by LSC. In addition, free DNA was subjected to gel electrophoresis, DNA bands in the gels were stained with ethidium bromide (EB), and the gels were rinsed with a solution of CFN or PBS to bleach the DNA band's fluorescence. Results Rinsing the PI or 7-AAD–stained cells with solutions of CFN led to nearly complete removal of PI and a more than 75% decrease in 7-AAD fluorescence after 10 min. The rinse with PBS decreased the PI cell fluorescence intensity by less than 30% and the 7-AAD fluorescence by about 50%. The differences in kinetics of PI or 7-AAD removal by CFN from G2/M versus G1 cells suggest that these intercalators bind more strongly to DNA in chromatin of G2/M than G1 cells. The CFN-bleached cells were then successfully stained with S101 and again with PI or 7-AAD. The bivariate analysis of the LSC merged files of the cells sequentially stained with PI and S101 revealed typical DNA/protein distributions. The fluorescence of EB-stained DNA bands in gels was also nearly completely removed by rinsing gels in 0.05 M CFN; PBS alone had a distinctly lesser effect. Conclusion Solutions of CFN can dissociate the DNA-bound PI, 7-AAD, EB, and possibly other intercalating fluorochromes. The bleached cells can be restained and reanalyzed by LSC. This approach can also be used to remove such fluorochromes from nucleic acids immobilized in gels and perhaps in other solid matrices. Analysis of the kinetics of fluorochrome removal from cells can possibly be used to study their binding affinities to nucleic acids in situ. Cytometry 43:38–45, 2001. © 2001 Wiley-Liss, Inc.
Electrostatic field effects of coenzymes on ligand binding to catalytic zinc in liver alcohol dehydrogenase (1984)

The synergism between coenzyme and anion binding to liver alcohol dehydrogenase has been examined by equilibrium measurements and transient-state kinetic methods to characterize electrostatic interactions of coenzymes with ligands which are bound to the catalytic zinc ion of the enzyme subunit. Inorganic anions typically exhibit an at least 200-fold higher affinity for the general anion-binding site than for catalytic zinc on complex formation with free enzyme. Acetate and SCN- interact more strongly with catalytic zinc in the enzyme X NAD+ complex than with the general anion-binding site in free enzyme. CN- shows no significant affinity for the general anion-binding site, but combines to catalytic zinc in the absence as well as the presence of coenzymes. Coordination of CN- to catalytic zinc weakens the binding of NADH by a factor of 50, and tightens the binding of NAD+ to approximately the same extent through interactions which do not include any contributions from covalent adduct formation between CN- and NAD+. These observations provide unambiguous information about the magnitude of electrostatic field effects of coenzymes on anion (e.g. hydroxyl ion) binding to catalytic zinc. They lead to the important inference that coenzyme binding must be strongly affected by ionization of zinc-bound water irrespective of the actual acidity of the latter group. It is concluded on such grounds that the much debated pH dependence of coenzyme binding to liver alcohol dehydrogenase must derive from ionization of zinc-bound water. The assumption that such is not the case leads to the inference that there is no detectable effect of ionization of zinc-bound water on coenzyme binding over the pH range 6-12, a possibility which is definitely excluded by the present results.
Surgical correction of presbyopia (2016)

Proprietary or commercial disclosures are listed after the references.
Localized imaging using stimulated echoes (1987)

Stimulated-echo localized spectroscopy was combined with phase- and frequency-encoding gradients to obtain "zoom" or magnified images of specific organs in situ. The technique requires neither surface coils nor an imaging coil arrangement that exclusively isolates the target organ. This technique can be readily applied to conventional spectrometer imagers that have limited computational capabilities.
Effects of a Modified Sandblasting Surface Treatment on Topographic and Chemical Properties of Titanium Surface (2001)

A modified sandblasting surface treatment (a noncoating, roughening surface modification of dental implants) has been developed that will overcome the defects of conventional coating techniques. To verify the feasibility and reliability of this method at the chemical and topographic levels, scanning electron microscopy, x-ray diffraction, and a titanium ion releasing test were used; the topography of titanium surface, the embedding of sandblasting particles, nonpollution of heteroelements, and anticorrosiveness of titanium were criteria. Results showed that the rough surface created by sandblast was rather irregular, full of sharp tips and many embedded sandblast particles, and its corrosive rate was increased. These characteristics were modified by oxalic acid attack; the contour of the rough surface became more regular and round, the embedded particles and the heteroelement pollution were thoroughly removed, and the Ti corrosive rate decreased dramatically. Oxalic acid attack modification also created numerous secondary micropores (2.0-micron diameter) on the basis of sandblasted surface macrotexture. This modified sandblasting surface treatment is feasible and reliable to apply to dental implants and does not decrease the biocompatibility of titanium.
A Profile of Mentally Ill Offenders and their Adjustment in the Community (1991)

The research focuses on a little-studied group of mentally disordered offenders: inmates requiring psychiatric hospitalization during imprisonment. Information is provided on the pre-prison and prison histories of all male mentally ill offenders (MIOs) released during a 13-month period (N = 150) and followed for 18 months in the community. Results indicate that MIOs displayed a marginal existence prior to their incarceration, with the vast majority having had a prior criminal and/or psychiatric contact. Problems in both domains continued upon release into the community. By followup's end, 48% required at least one psychiatric commitment, and 64% experienced at least one rearrest. Multiple regression indicated that recidivism among MIOs was associated with standard criminological variables: age and prior criminal record. These findings are then compared with research on other mentally disordered offender groups.
Carbon Dioxide Transport Plans for Carbon Capture and Storage in the North Sea Region - A summary of existing studies and proposals applicable to the development of Projects of Common Interest (2023)

The European Commission has made funding available for identified Projects of Common Interest (PCI) in energy infrastructure through its Connecting Europe Facility (European Commission, 2015a). A Project of Common Interest is a project necessary to implement the energy infrastructure priority corridors and thematic areas defined by the European Parliament; one priority thematic area is cross-border transport of CO2 for CCS (European Parliament, 2013). The identification and selection of PCIs for inclusion in the list of supported projects is made by regional or thematic groups consisting of the Commission, relevant Member States and project promoters. A thematic group for CO2 transport is currently being created (mid-2015), and criteria for project selection are being discussed. To inform this process the present document gives an overview of CO2 transport concepts and projects for CCS that have been proposed or assessed to date for the North Sea and wider European region.
Mass Spectrometry–Based Metabolic Profiling Reveals Different Metabolite Patterns in Invasive Ovarian Carcinomas and Ovarian Borderline Tumors (2006)

Metabolites are the end products of cellular regulatory processes, and their levels can be regarded as the ultimate response of biological systems to genetic or environmental changes. We have used a metabolite profiling approach to test the hypothesis that quantitative signatures of primary metabolites can be used to characterize molecular changes in ovarian tumor tissues. Sixty-six invasive ovarian carcinomas and nine borderline tumors of the ovary were analyzed by gas chromatography/time-of-flight mass spectrometry (GC-TOF MS) using a novel contamination-free injector system. After automated mass spectral deconvolution, 291 metabolites were detected, of which 114 (39.1%) were annotated as known compounds. By t test statistics with P < 0.01, 51 metabolites were significantly different between borderline tumors and carcinomas, with a false discovery rate of 7.8%, estimated with repeated permutation analysis. Principal component analysis (PCA) revealed four principal components that were significantly different between both groups, with the highest significance found for the second component (P = 0.00000009). PCA as well as additional supervised predictive models allowed a separation of 88% of the borderline tumors from the carcinomas. Our study shows for the first time that large-scale metabolic profiling using GC-TOF MS is suitable for analysis of fresh frozen human tumor samples, and that there is a consistent and significant change in primary metabolism of ovarian tumors, which can be detected using multivariate statistical approaches. We conclude that metabolomics is a promising high-throughput, automated approach in addition to functional genomics and proteomics for analyses of molecular changes in malignant tumors.
<i>Aspergillus</i>Enzymes Involved in Degradation of Plant Cell Wall Polysaccharides (2001)

Degradation of plant cell wall polysaccharides is of major importance in the food and feed, beverage, textile, and paper and pulp industries, as well as in several other industrial production processes. Enzymatic degradation of these polymers has received attention for many years and is becoming a more and more attractive alternative to chemical and mechanical processes. Over the past 15 years, much progress has been made in elucidating the structural characteristics of these polysaccharides and in characterizing the enzymes involved in their degradation and the genes of biotechnologically relevant microorganisms encoding these enzymes. The members of the fungal genus Aspergillus are commonly used for the production of polysaccharide-degrading enzymes. This genus produces a wide spectrum of cell wall-degrading enzymes, allowing not only complete degradation of the polysaccharides but also tailored modifications by using specific enzymes purified from these fungi. This review summarizes our current knowledge of the cell wall polysaccharide-degrading enzymes from aspergilli and the genes by which they are encoded.
Status and outlook of sensitizers/dyes used in dye sensitized solar cells (DSSC): a review (2016)

Dye-sensitized solar cells (DSSCs) have become a topic of significant research in the last two decades because of their scientific importance in the area of energy conversion. Currently, DSSC is using inorganic ruthenium (Ru)-based, metal-free organic dyes, quantum-dot sensitizer, perovskite-based sensitizer, and natural dyes as sensitizer. The use of metal-free, quantum-dot sensitizer, perovskite-based sensitizer, and natural dyes has become a viable alternative to expensive and rare Ru-based dyes because of low cost, ease of preparation, easy attainability, and environmental friendliness. Most of the alternatives to Ru-based dyes have so far proved inferior to the Ru-based dyes because of their narrow absorption bands (Δλ ≈ 100–250 nm), adverse dye aggregation, and instability. This review highlights the recent research on sensitizers for DSSC, including ruthenium complexes, metal-free organic dyes, quantum-dot sensitizer, perovskite-based sensitizer, mordant dyes, and natural dyes. It also details and tabulates all types of sensitizer with their corresponding efficiencies. Plot of progress in efficiency (η) of DSSC till date based on different types of sensitizers is also presented. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.
Generation and transmission of optical solitons in the gigahertz region using a directly modulated distributed-feedback laser diode (1990)

We have succeeded for the first time, to our knowledge, in the generation and transmission of 6–24-GHz, 17-psec transform-limited solitons, using a directly modulated distributed-feedback laser diode with a narrow-band spectral filter and erbium-doped optical fiber amplifiers. The average optical power at 6 GHz from the erbium amplifier is greater than 10 mW, which corresponds to a peak power of 98 mW. The peak power is already in the soliton power regime for dispersion-shifted fibers. The solitons are transmitted over 22 km, and their original width can be completely preserved. The soliton-narrowing effect and high-order solitons that divide are also observed.
Fast plane detection and polygonalization in noisy 3D range images (2008)

A fast but nevertheless accurate approach for surface extraction from noisy 3D point clouds is presented. It consists of two parts, namely a plane fitting and a polygonalization step. Both exploit the sequential nature of 3D data acquisition on mobile robots in form of range images. For the plane fitting, this is used to revise the standard mathematical formulation to an incremental version, which allows a linear computation. For the polygonalization, the neighborhood relation in range images is exploited. Experiments are presented using a time-of-flight range camera in form of a Swissranger SR-3000. Results include lab scenes as well as data from two runs of the rescue robot league at the RoboCup German Open 2007 with 1,414, respectively 2,343 sensor snapshots. The 36 <b xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">ldr</b> 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">6</sup> , respectively 59 <b xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">ldr</b> 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">6</sup> points from the two point clouds are reduced to about 14ldr10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> , respectively 23 <b xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">ldr</b> 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> planes with only about 0.2 sec of total computation time per snapshot while the robot moves along. Uncertainty analysis of the computed plane parameters is presented as well.
Vesicular autoantigens of Type 1 diabetes (1998)

Type 1 diabetes, also referred to as insulin-dependent diabetes mellitus (IDDM), is an autoimmune disorder resulting from the destruction of pancreatic beta-cells and insulin deficiency. In the last 10 years significant progress has been made in this field, primarily because of the identification of predisposing genes, the extensive investigation of animal models, and the characterization of major autoantigens. This review draws attention to how the study of beta-cell autoantigens may contribute insight into the pathogenesis of IDDM and provides an update on the cell biology of glutamic acid decarboxylase (GAD) and islet cell autoantigen 512, two major targets of autoimmunity in Type 1 diabetes on which I have focused my efforts. For reasons of space I have mostly considered here studies on GAD which have been published since 1994.
4G, LTE-Advanced Pro and The Road to 5G, Third Edition (2016)

The upcoming 5G specifications from 3GPP, to be available in 2018, will include LTE-Advanced Pro as well as a new 5G radio-access technology. This practical and very successful book, written by engineers working closely with 3GPP, gives insight into the newest technologies and standards adopted by 3GPP, with detailed explanations of the specific solutions chosen and their implementation in LTE, LTE-Advanced, and LTE-Advanced Pro, as well as providing a detailed description of the path to 5G and the associated underlying technologies. This edition has been thoroughly revised and updated to reflect the large extensions to LTE as introduced in 3GPP Releases 12 and 13 and the role of LTE in the upcoming 5G era. New to this edition includes updated content on: 4G and 5G Radio Access Spectrum for 4G and 5G Machine-Type Communication Device-to-Device Communication License-assisted Access Full-dimension MIMOSmall-cell enhancements, eIMTA, FDD+TDD aggregation, dual connectivity Requirements on and general structure of 5G wireless access, addressing the existing and new usage scenarios for 5GTechnical solutions for the new 5G radio-access technology The authors of this book all work at Ericsson Research and have been deeply involved in 3G and 4G development and standardization. They are leading experts in the field and are today actively contributing to the standardization of 4G and 5G within 3GPP. The leading book on 3GPP specifications for LTE, LTE-Advanced, and LTE-Advanced Pro covering up to and including Release 13, written by Ericsson engineers who are heavily involved in the development of 3GPP specificationsTen new chapters and coverage of all major features introduced with Release 12 and 13Two completely new chapters on 5G wireless access including a detailed description of the key technology components under development by 3GPP
Clinical Markers of Anxiety Subtypes in Parkinson Disease (2018)

Persistent anxiety is mainly influenced by nonspecific markers, while episodic anxiety seems to be more PD-specific compared to persistent anxiety and may be more situational or contextual. These results provide support for possible distinct underlying constructs for anxiety subtypes in PD.