gebhart/patrepeval huggingface dataset:
UA-DETRAC 2018: Report of AVSS2018 & IWT4S Challenge on Advanced Traffic Monitoring (2018)

A desirable smart traffic-monitoring and street-safety system can elicit and support the intervention of law enforcement agencies or medical staff. Recently, there has been a dramatically higher demand for such smart systems. To this end, the International Workshop on Traffic and Street Surveillance for Safety and Security (IWT4S) was organized in conjunction with the 15th IEEE International Conference on Advanced Video and Signal-based Surveillance (AVSS 2018). Our goal is to advance the state-of-the-art detection and tracking algorithms and provide a comprehensive performance evaluation for them. We evaluate 5 submitted detection and 7 submitted tracking methods on the large-scale UA-DETRAC benchmark, and the results are shared publicly on the website http://detrac-db. rit.albany.edu. We expect this challenge to advance the research and development of new detection and tracking methods for transportation applications.
Molecular Targets and Targeted Therapies for Malignant Mesothelioma (2008)

Malignant mesothelioma is a highly invasive tumor originating from the mesothelial linings of the pleura, peritoneum and pericardium. It is seldom amenable to surgical intervention and poorly responsive to radiotherapy, leaving chemotherapy as the main therapeutic option for most patients. The development of effective drug regimens against mesothelioma has proven extremely difficult and a standard first-line treatment for patients with unresectable tumors has not been established until recently. Despite the benefits obtained with this newly validated standard of care, which is based on the combination of pemetrexed and cisplatin, the prognosis for mesothelioma patients remains poor, median survival is still less than two years and more active treatments are urgently needed. This article will focus on the molecular basis providing the rationale for targeted interventions against mesothelioma and will review targeted agents under evaluation as new potential therapeutic options for mesothelioma patients. Such agents include inhibitors of growth factor receptors, ligands and intracellular effectors. The agents targeting vascular endothelial growth factor signaling are of particular interest, due to the involvement of this pathway both in tumor angiogenesis and autocrine stimulation of mesothelioma cell growth. Alternative approaches are based on inhibitors of the ubiquitin-proteasome pathway and of histone deacetylases which, notwithstanding the functional divergence of the corresponding targets, share the ability to determine a wide modulation of the cancer cell phenotype that can lead to cell cycle arrest, apoptosis and sensitization to different antineoplastic treatments. A recombinant immunotoxin targeted to the membrane antigen mesothelin is an additional agent whose activity is being evaluated in mesothelioma patients. Keywords: Mesothelioma, molecular therapy, receptor tyrosine kinase inhibitors, bevacizumab, rapamycin, bortezomib, histone deacetylase inhibitors, mesothelin
A Framework of a Transcoder Controlling Scheme over Multicast Networks (2005)

Recently, video transmission services over networks are getting very popular thanks to the development of network infrastructure. From the viewpoint of efficient network bandwidth utilization, multicast is a key technology that provides high QoS services. However, it is very difficult to obtain high QoS for each individual user since the requirement and environment of each user is so different due to the heterogeneity of current network and terminals. Hence we propose a transcoder controlling scheme that enable each user to obtain high QoS by utilizing transcoders. We assume that transcoder functionality will be installed over routers in the future next generation network, and hence, our proposed scheme is based on the network. The proposed scheme manipulates multicast trees and transcoders in the network. Moreover, the proposed scheme minimizes the deterioration of video streams caused by transcoding procedures by limiting the number of transcoding. Even more, the proposed scheme does not cause any extra delay by manipulating multicast tree. Finally, simulation experiments evaluate the proposed scheme from the viewpoint of network bandwidth consumption and clarify the efficiency and the effectiveness of the proposed scheme.
Ultralow-energy electro-absorption modulator consisting of InGaAsP-embedded photonic-crystal waveguide (2017)

Towards realizing highly integrable low-energy optical modulators, the small device capacitance (C) as well as the low driving voltage (Vpp) is demanded for suppressing the charging energy during the dynamic operation. Although an electro-absorption modulator (EAM) has great potential in reducing them, the additional energy associated with the photocurrent flow will limit the lower-bound of the consumption energy. In this work, a broadband EAM based on an InGaAsP-embedded photonic crystal waveguide is demonstrated, revealing a high modulation bit rate of up to 56 Gbit/s. The air-bridge structure and a device length of 100 μm or less result in a small C ≤ 13 fF while operating with Vpp &lt; 1 V. Particularly, the operation in low reverse voltage for a p-i-n junction, that is, −0.2 V as the minimum value in this study, works effective for the reduction of energy involving the photocurrent. This results in the total electrical energy consumption of &lt;2 fJ/bit, which is lower than that of any waveguide EAMs.
Considerations for a national heart attack alert program. (1990)

Coronary heart disease (CHD) remains the leading cause of death in the United States--in women as well as men. In 1987, CHD was responsible for 512,138 deaths, of which 253,542 deaths were attributed to acute myocardial infarction (AMI) and accounted for over $43 billion in direct and indirect costs. The disease spares no one. Primary prevention is clearly important, but for those in whom primary prevention has not been applied or has failed, acting to minimize the effect of a heart attack is of paramount importance. Many of its victims do not obtain appropriate medical care, or obtain it too late for the latest lifesaving technologies to be effective. The goal of treatment is to prevent death and to salvage as much heart tissue as possible. To achieve this goal, it is essential to minimize the time from the first symptoms and signs to treatment. Opportunities exist at each phase of an evolving AMI to intervene promptly and appropriately to prevent sudden death and to preserve cardiac muscle and thereby reduce CHD morbidity and mortality. Yet, formidable problems also exist. These and other issues are presently being studied by the National Heart, Lung, and Blood Institute staff and advisors in consideration of whether to establish a national educational program aimed at reducing CHD morbidity and mortality through the rapid identification and treatment of those with AMI.
Research of the Belt Conveyor Starting Acceleration Based on AMESim (2014)

Based on AMESim, by the analysis of the Conveyor Belt four discrete model, Select and built the Kelvin-Voigt model which is simple and applicable, by comparative analysis of drawing on four commonly used to start the acceleration (uniform acceleration, triangle acceleration, trapezoidal acceleration and the Harrison), Select the Harrison speed as the starting acceleration and Using AMESim to establish the starting model of acceleration.
Cancer-radiotherapy equipment as a cause of soft errors in electronic equipment (2005)

The undesirable production of secondary neutrons by cancer-radiotherapy linear accelerators (linac) has been demonstrated to cause soft errors in nearby electronics through the /sup 10/B(n,a)/sup 7/Li reaction. /sup 10/B is a component in the BPSG used as a dielectric material in some integrated-circuit (IC) fabrication processes.
Effects of X irradiation on angiogenesis. (1990)

We have evaluated the effect of X irradiation on the mesenchymal tissue growth (blood capillaries and stromal cells) in an angiogenesis system in the mouse. This was accomplished by implanting a polyvinyl alcohol sponge disc in the subcutis of the thorax, and quantifying the extent of growth reduction of capillaries and stromal cells following graded doses of X rays. The sponge disc contained a centrally located pellet impregnated with 20 micrograms of epidermal growth factor and coated with a thin film of slow-releasing compound. Total growth of vessels and fibroblasts was determined by morphometric analysis of histologic sections. The incorporation of [3H]TdR was measured during a 24-h period. A dose-response relationship was observed when X irradiation was given on Day 11 after implantation, with the disc removed on Day 20. A single dose of 15 Gy reduced both the rate of incorporation of [3H]TdR and the total growth area. These and previous observations point to endothelial cells as important targets of ionizing radiation in the stroma, especially during the period of active proliferation of these cells, induced by growth factors.
Understanding the molecular basis of autism in a dish using hiPSCs-derived neurons from ASD patients (2015)

Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder characterized by deficits in social cognition, language development, and repetitive/restricted behaviors. Due to the complexity and heterogeneity of ASD and lack of a proper human cellular model system, the pathophysiological mechanism of ASD during the developmental process is largely unknown. However, recent progress in induced pluripotent stem cell (iPSC) technology as well as in vitro neural differentiation techniques have allowed us to functionally characterize neurons and analyze cortical development during neural differentiation. These technical advances will increase our understanding of the pathogenic mechanisms of heterogeneous ASD and help identify molecular biomarkers for patient stratification as well as personalized medicine. In this review, we summarize our current knowledge of iPSC generation, differentiation of specific neuronal subtypes from iPSCs, and phenotypic characterizations of human ASD patient-derived iPSC models. Finally, we discuss the current limitations of iPSC technology and future directions of ASD pathophysiology studies using iPSCs.
Small Business Research Program (1985)

The U.S. Department of Energy (DOE) invites small businesses, or those with 500 employees or less, to write for a copy of its Small Business Innovation Research (SBIR) program solicitation, to be issued January 2, 1985. To receive a copy, contact the SBIR Program Manager, U.S. Department of Energy, Washington, DC 20545; telephone 301‐353‐5707. The closing date for this solicitation is March 15, 1985.
Tribological properties of carbon nanotubes as lubricant additives (2009)

Tribological performances of innovative lubricant additives based on IF-WS2 and other transition metal dichalcogenides like MoS2 nanoparticles have been widely investigated in recent years. The boundary lubrication regime is the main target for the benefits of well-tested or potential additives, since the film thickness of the lubricating base is no longer sufficient to preserve separation of the opposing metal surfaces. Among the various investigated materials, nanocarbons such as fullerenes and nanotubes have proven attractive and promising tribological properties in terms of friction reduction and anti-wear action. In this work experiments have been carried out on a pin-on-disc tribometer to get assessment about the effectiveness of such additives as friction reducers in boundary and mixed lubrication regimes. Multiwalled carbon nanotubes of different geometric characteristics (diameter, length, thickness) were obtained by catalytic CVD. Several tests, performed on arrays of operating conditions in terms of speeds and loads, have aimed to underline the friction loss saving of the lubricated pair by varying nanoadditive concentration in the oil formulation. AISI 316 steel pins with different surface finish have been used to consider the effect of roughness parameters, while the counterpart surface is an X155Cr13MoKu steel disc, 60 HRC.
Inorganic Polyphosphate in <i>Escherichia coli</i> : the Phosphate Regulon and the Stringent Response (1998)

Escherichia coli transiently accumulates large amounts of inorganic polyphosphate (polyP), up to 20 mM in phosphate residues (Pi), in media deficient in both Pi and amino acids. This transient accumulation is preceded by the appearance of nucleotides ppGpp and pppGpp, generated in response to nutritional stresses. Mutants which lack PhoB, the response regulator of the phosphate regulon, do not accumulate polyP even though they develop wild-type levels of (p)ppGpp when subjected to amino acid starvation. When complemented with a phoB-containing plasmid, phoB mutants regain the ability to accumulate polyP. PolyP accumulation requires high levels of (p)ppGpp independent of whether they are generated by RelA (active during the stringent response) or SpoT (expressed during Pi starvation). Hence, accumulation of polyP requires a functional phoB gene and elevated levels of (p)ppGpp. A rapid assay of polyP depends on its adsorption to an anion-exchange disk on which it is hydrolyzed by a yeast exopolyphosphatase.
Importance of Pressure Recovery for the Assessment of Aortic Stenosis by Doppler Ultrasound (1996)

Significant pressure recovery can occur in aortic stenosis and can cause differences between Doppler and catheter gradients. These differences may reach clinical relevance, particularly when the stenosis is moderate and the aorta is small and can be predicted from Doppler measurements.
Blending Traditional and Western Medicine: Medicinal plant use among patients at Clinica Anticona in El Porvenir, Peru (2007)

Medicinal plants have been used in Peru for millennia for a variety of uses, but, over the last century, modern technology has deterred the increased growth of this valuable knowledge. The present study attempts to look at a clinic in El Porvenir, on the north coast of Peru to discover what kind of medicines are preferred and the factors determining choices made. Previous studies have shown that medicinal plants still play an important role in treatment. However, the results of our study demonstrate that pharmaceutical medicine plays a larger role when compared to the use of medicinal plants. Thus, while many patients feel pharmaceutical medicine is faster and more effective, there are still a large number of plants that are commonly used by patients. As a result, there is evidence that more research in this area should be done in order to learn what factors determine medical choices and what factors might lead to an increase the use of medicinal plants.
Implementation of HLS Protocol for an IP Camera (2014)

HTML5 is designed to deliver almost everything you want to do without requiring additional plugins. We produced an implementation of a HTTP Live Streaming (HLS) for an IP camera to provide live streaming by using elements of HTML5 for media playback. This implementation follows HLS standard in which we utilizes an open-source library named FFmpeg. A conclusion of this paper is that live steaming on mobile devices over HTTP is achieved without any plugins.
The Tumor Suppressor Gene TP53: Implications for Cancer Management and Therapy (2004)

The p53 protein is an inducible transcription factor with multiple anti-proliferative roles in response to genotoxic damage; unprogrammed proliferative stimuli; and deprivation of oxygen, nutrients, or ribonucleotides. Inactivation of the TP53 gene by mutation or deletion is the most common event in human cancer. Loss of p53 function compromises genetic homeostasis in cells exposed to mutagens and prevents normal cytotoxic responses to cancer therapies. Genetic and pharmacological approaches are being developed with the ultimate goal of restoring or controlling p53 functions in cancer patients. Genetic interventions aiming at expressing wild-type TP53 in cancer cells, either by retroviral or adenoviral transfer, have met limited clinical success. However, recently, the use of a defective adenovirus (ONYX-015) that selectively kills p53-incompetent cells has shown promising effects in pre-clinical and clinical studies. Pharmacological methods are under development to either stimulate wild-type p53 protein function or induce p53 mutant proteins to resume wild-type functions. These methods are based on small chemicals (CP-31388, PRIMA-1), peptides (CDB3), or single-chain Fv antibody fragments corresponding to defined p53 domains. In addition, detection of mutant TP53 may also serve as a marker for early cancer detection, prediction, and prognosis. In this review, we discuss the mechanisms underlying these approaches and their perspectives for cancer therapy.
Bioavailability of diazepam after intramuscular injection of its water‐soluble prodrug alone or with atropine–pralidoxime in healthy volunteers (2009)

Diazepam had a faster entry to the general circulation and achieved higher C(max) after injection of prodrug than after the parent drug. Administration of avizafone in combination with atropine and pralidoxime by AIBC had no significant effect on diazepam AUC and C(max).
Artificial Noise Generation from Cooperative Relays for Everlasting Secrecy in Two-Hop Wireless Networks (2011)

The secure transmission of information in wireless networks without knowledge of eavesdropper channels or locations is considered. Two key mechanisms are employed: artificial noise generation from system nodes other than the transmitter and receiver, and a form of multi-user diversity that allows message reception in the presence of the artificial noise. We determine the maximum number of independently-operating and uniformly distributed eavesdroppers that can be present while the desired secrecy is achieved with high probability in the limit of a large number of system nodes. While our main motivation is considering eavesdroppers of unknown location, we first consider the case where the path-loss is identical between all pairs of nodes. In this case, a number of eavesdroppers that is exponential in the number of systems nodes can be tolerated. In the case of uniformly distributed eavesdroppers of unknown location, any number of eavesdroppers whose growth is sub-linear in the number of system nodes can be tolerated. The proposed approach significantly outperforms a power control approach based on standard multi-user diversity.
European Consensus Statement on Lung Cancer: risk factors and prevention. Lung Cancer Panel (1998)

This article is based on discussions of the lung cancer panel at the Hohenheim Consensus Meeting organized by the World Health Organization and the German Ministry of Health in November 1996. Panel members were international experts in the field of diet and cancer who discussed specific questions relating to lung cancer risk factors and prevention.
Learning Connective-based Word Representations for Implicit Discourse Relation Identification (2016)

We introduce a simple semi-supervised approach to improve implicit discourse relation identification. This approach harnesses large amounts of automatically extracted discourse connectives along with their arguments to construct new distributional word representations. Specifically, we represent words in the space of discourse connectives as a way to directly encode their rhetorical function. Experiments on the Penn Discourse Treebank demonstrate the effectiveness of these task-tailored representations in predicting implicit discourse relations. Our results indeed show that, despite their simplicity, these connective-based representations outperform various off-the-shelf word embeddings, and achieve state-of-the-art performance on this problem.
Enhanced IRC-SIC algorithm with beamforming for MU-MIMO systems (2015)

One of the most important benefits of Multiple-Input Multiple-Output (MIMO) systems to multi-user (MU) scenarios seems to consist in achieving high data rate useful for future cellular systems. In order to eliminate interference in MU-MIMO systems, a number of low-complexity interference aware type of receivers were proposed. In this paper an enhanced Interference Rejection Combining (IRC) algorithm and Successive Interference Cancellation (SIC) with possible application for Long Term Evolution (LTE) is developed. The performance of the proposed detection algorithm is compared with the one of other receiver detection algorithms such as: Zero-Forcing (ZF), Minimum Mean Square Error (MMSE) and Maximum Likelihood (ML). Simulation results show that the proposed algorithm can effectively detect Inter-Cell Interference (ICI) and improve the Bit Error Rate (BER) performance making it suitable for LTE downlink receivers.
Detection and analysis of web-based malware and vulnerability (2018)

Since the dawn of the Internet, all of us have been swept up by the Niagara of information that fills our daily life. In this process, browsers play an extremely important role. Modern browsers have turned from a simple text displayer to a complicated software that supports rich user interfaces and a variety of file formats and protocols. This enlarges the attack surface and makes browsers one of the main targets of cyber attack.
Preparation of B-.sigma.-carboranyl iridium complexes by oxidative addition of terminal boron-hydrogen bonds to iridium(I) species (1975)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPreparation of B-.sigma.-carboranyl iridium complexes by oxidative addition of terminal boron-hydrogen bonds to iridium(I) speciesElvin L. Hoel and M. Frederick HawthorneCite this: J. Am. Chem. Soc. 1975, 97, 22, 6388–6395Publication Date (Print):October 1, 1975Publication History Published online1 May 2002Published inissue 1 October 1975https://pubs.acs.org/doi/10.1021/ja00855a017https://doi.org/10.1021/ja00855a017research-articleACS PublicationsRequest reuse permissionsArticle Views520Altmetric-Citations99LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The influence of speckle statistics on contrast metrics in ultrasound imaging (2017)

Adaptive beamformers aim for improved resolution and contrast in the ultrasound images, and their performance is typically benchmarked using metrics such as contrast ratio (CR) and contrast-to-noise ratio (CNR). Using synthetic aperture Field II simulations, we show that certain beamformers alter speckle statistics and that this opens up for cherry picking of contrast metrics.