gebhart/patrepeval huggingface dataset:
Alike performance during nonverbal episodic learning from diversely imprinted neural networks (2003)

Performance on neuropsychological testing permits inferences to be made regarding neural networks required to solve the task. In healthy young human subjects it is common sense that differential performance in cognitive tasks results from recruitment of different neural networks and that alike performance results from recruitment of alike neural networks. It was the goal of the present study to investigate whether these assumptions are also valid in cross-cultural studies. To address this, we used functional MRI during a nonverbal episodic memory task with repeated learning of abstract geometric patterns. Behavioural performance in this task was alike over repeated trials in native Chinese and Caucasian subjects. Given this equivalent performance, the distinct pattern of neuronal activation observed is interpreted as the outcome of different culturally imprinted processing routines. In the 'what' and 'where' framework of visuo-spatial processing initial learning in Chinese subjects activated the dorsal stream for analysis of spatial features whereas Caucasians recruited the ventral stream for object identification. With repeated learning Chinese subjects integrated visuo-spatial processing to object coding and vice versa. Thus, imprints of culture result in activation of distinct neural networks and mandate monitoring of both behavioural performance and neural recruitment in cross-cultural studies of cognition.
Capsule-Forensics: Using Capsule Networks to Detect Forged Images and Videos (2018)

Recent advances in media generation techniques have made it easier for attackers to create forged images and videos. State-of-the-art methods enable the real-time creation of a forged version of a single video obtained from a social network. Although numerous methods have been developed for detecting forged images and videos, they are generally targeted at certain domains and quickly become obsolete as new kinds of attacks appear. The method introduced in this paper uses a capsule network to detect various kinds of spoofs, from replay attacks using printed images or recorded videos to computer-generated videos using deep convolutional neural networks. It extends the application of capsule networks beyond their original intention to the solving of inverse graphics problems.
Classical and non-classical HLA class I aberrations in primary cervical squamous- and adenocarcinomas and paired lymph node metastases (2016)

These results strengthen the idea of tumor immune escape variants leading to metastasis. Moreover, SCC tumors showing downregulation of HLA-A or total classical HLA in combination with HLA-G expression had poor prognosis. Our findings warrant further analysis of HLA expression as a biomarker for patient selection for CTL- and NK- cell based immunotherapeutic intervention.
The antimicrobial spectra of some salts of organic acids and glutaraldehyde in respect to their potential as silage additives (1984)

Abstract Salts of formic, acetic and propionic acids and glutaraldehyde were subjected to an assay with representatives of the major groups of silage micro‐organisms at pH 4·0, 4·5, 5·0 and 6·0. The antimicrobial spectra of the salts suggested that they are most effective against the least desirable components of the bacterial flora of silage, coliforms, Clostridia and bacilli, and would create conditions for a desirable fermentation in practice. In many instances the activity of the salts was better than the corresponding free acid and it was postulated that, if supplemented with acid, aerobic stability of silage might also be improved. Glutaraldehyde, whilst being less selective as an antimicrobial agent, possesses properties which would encourage a lactic‐acid fermentation in silage.
Holocephalan (Chondrichthyes) dental plates with hypermineralized dentine as a substitute for missing teeth through developmental plasticity (2020)

All extant holocephalans (Chimaeroidei) have lost the ability to make individual teeth, as tooth germs are not part of the embryonic development of the dental plates or of their continuous growth. Instead, a hypermineralized dentine with a unique mineral, whitlockin, is specifically distributed within a dentine framework into structures that give the dental plates their distinctive, species-specific morphology. Control of the regulation of this distribution must be cellular, with a dental epithelium initiating the first outer dentine, and via contact with ectomesenchymal tissue as the only embryonic cell type that can make dentine. Chimaeroids have three pairs of dental plates within their mouth, two in the upper jaw and one in the lower. In the genera Chimaera, Hydrolagus and Harriotta, the morphology and distribution of this whitlockin within each dental plate differs both between different plates in the same species and between species. Whitlockin structures include ovoids, rods and tritoral pads, with substantial developmental changes between these. For example, rods appear before the ovoids and result from a change in the surrounding trabecular dentine. In Harriotta, ovoids form separately from the tritoral pads, but also contribute to tritor development, while in Chimaera and Hydrolagus, tritoral pads develop from rods that later are perforated to accommodate the vasculature. Nevertheless, the position of these structures, secreted by the specialized odontoblasts (whitloblasts), appears highly regulated in all three species. These distinct morphologies are established at the aboral margin of the dental plate, with proposed involvement of the outer dentine. We observe that this outer layer forms into serially added lingual ridges, occurring on the anterior plate only. We propose that positional, structural specificity must be contained within the ectomesenchymal populations, as stem cells below the dental epithelium, and a coincidental occurrence of each lingual, serial ridge with the whitlockin structures that contribute to the wear-resistant oral surface.
Detection, isolation, and functional characterization of two human T-cell subclasses bearing unique differentiation antigens. (1977)

A heterologous antihuman T-cell serum (anti-TH1), raised against purified peripheral T cells, and absorbed with an autologous Ig+ line, was shown to bind specifically to T- but not to B-lymphoid cells by both a complement-dependent cytotoxic assay and indirect immunofluorescence. Whereas 90% fetal thymocytes and thymocytes were killed by anti-TH1 and complement, a consistently restricted population (50-60%) of peripheral T cells from several normal donors were lysed, indicating that anti-TH1 is directed against one or more thymus-specific antigens which are lost or reduced on a subpopulation of human T cells in the periphery. Functional analysis of the unreactive (TH1-) and reactive (TH1+) T-cell subclasses demonstrated that TH1- cells mounted a good proliferative response to a battery of specific soluble antigens (mumps, PPD, tetanus toxoid) but neither responded in MLC, nor elaborated LMF in response to tetanus toxoid. In contrast TH1+ cells proliferated in MLC and elaborated LMF but did not respond by 3H-incorporation to soluble antigens. The relevance of these findings to human T-cell functions in vivo and to previously described functional subclasses of murine T cells is discussed.
Leukocytes Of Patients With Schistosoma Mansoni Respond With A Th2 Pattern Of Cytokine Production To Mitogen Or Egg Antigens But With A Th0 Pattern To Worm Antigens (1994)

Cytokine responses of peripheral blood mononuclear cells from humans infected with Schistosoma mansoni were assessed. By ELISA and ELISPOT, persons with acute and hepatosplenic infections produced higher levels of interleukin (IL)-4 and IL-5 and higher frequencies of IL-4-producing cells in response to mitogen than did uninfected persons. In contrast, mitogen-induced production of the Th1 cytokine interferon-gamma (IFN-gamma) did not differ from that of uninfected controls. Upon stimulation with egg antigens, many patients responded with elevated IL-4 mRNA levels but displayed no appreciable increases in Th1 (i.e., IFN-gamma and IL-2) cytokine transcripts. Nevertheless, in cells stimulated with adult worm antigen, a more mixed Th0-type response was observed with production of both Th1 and Th2 cytokines. These results support previous findings in laboratory mice that schistosome infection results in increased production of Th2 cytokines. Unlike mice, infected humans do not display a generalized down-modulation in Th1 responses but instead show a selective deficiency in IFN-gamma and usually IL-2 responses to egg antigens.
A Cable-driven Parallel Mechanism for Capturing Object Appearance from Multiple Viewpoints (2007)

This paper presents the full proof of concept of a system for capturing the light field of an object. It is based on a single high resolution camera that is moved all around the object on a cable-driven end-effector. The main advantages of this system are its scalability and low interference with scene lighting. The camera is accurately positioned along hemispheric trajectories by observing target features. From the set of gathered images, the visual hull is extracted and can be used as an approximate geometry for mapping a surface light field. The paper describes the acquisition system as well as the modeling process. The ability of the system to produce models is validated with four different objects whose sizes range from 20 cm to 3 m.
Evaluation of Enhanced Sampling Provided by Accelerated Molecular Dynamics with Hamiltonian Replica Exchange Methods (2014)

Many problems studied via molecular dynamics require accurate estimates of various thermodynamic properties, such as the free energies of different states of a system, which in turn requires well-converged sampling of the ensemble of possible structures. Enhanced sampling techniques are often applied to provide faster convergence than is possible with traditional molecular dynamics simulations. Hamiltonian replica exchange molecular dynamics (H-REMD) is a particularly attractive method, as it allows the incorporation of a variety of enhanced sampling techniques through modifications to the various Hamiltonians. In this work, we study the enhanced sampling of the RNA tetranucleotide r(GACC) provided by H-REMD combined with accelerated molecular dynamics (aMD), where a boosting potential is applied to torsions, and compare this to the enhanced sampling provided by H-REMD in which torsion potential barrier heights are scaled down to lower force constants. We show that H-REMD and multidimensional REMD (M-REMD) combined with aMD does indeed enhance sampling for r(GACC), and that the addition of the temperature dimension in the M-REMD simulations is necessary to efficiently sample rare conformations. Interestingly, we find that the rate of convergence can be improved in a single H-REMD dimension by simply increasing the number of replicas from 8 to 24 without increasing the maximum level of bias. The results also indicate that factors beyond replica spacing, such as round trip times and time spent at each replica, must be considered in order to achieve optimal sampling efficiency.
A 104 GHz 328 fs soliton pulse train generation through a comb-like dispersion profiled fiber using short high nonlinearity dispersion fibers (2002)

We have constructed a 693.6 m long comb-like dispersion profiled fiber using a newly developed high-nonlinearity DSF, through which a dual frequency beat signal was compressed by 14.7 times to generate a 104 GHz train of 328 fs pulses.
Introduction (2008)

Textual criticism and editing of the New Testament have changed dramatically in the last quarter of a century. It is rather more than thirty years since I began my first researches in the field, and during this period of time I have had to learn new approaches in most of the things which I do. There are four main causes for this. Foremost among them is the introduction of the computer. In the last fifteen years the techniques of collecting manuscript evidence, analysing it, and making a critical edition have all undergone their greatest transformation. Secondly, the study of manuscripts has undergone significant changes. It has become plainer than ever before that the examination of manuscripts and of the variant readings which they contain is more than a means to recover a lost original text – it has also a part to play in the study of the development of Christian thought and in the history of exegesis. Thirdly, the publication of new manuscript discoveries continues to challenge traditional views of textual history and of the copying of texts. Fourthly, a number of research tools have been published which place far larger and better resources at the scholar's disposal than were ever available before. Nor does there seem to be any likelihood of the pace of change slackening in the near future. The advent of digital imaging heralds a new era, in which scholars and students everywhere will be able to view pictures of any page in any manuscript.
Multi-channel time division multiple access timeslot scheduling with link recovery for multi-hop wireless sensor networks (2017)

In this article, we propose a time division multiple access scheduling algorithm for end-to-end on-time packet delivery in multi-hop wireless sensor networks. Our proposed algorithm establishes a new communication path to substitute the old path including the link failed and schedules communication links on the new path by allocating timeslots satisfying end-to-end delay bound. Max–min optimization is employed to maximize the number of dedicated timeslots to establish the substitute path in the event of the next link failure. We evaluate the performance of the proposed algorithm using QualNet network simulator and compare it with the performance of the algorithm that minimizes the end-to-end delay. Our numerical results show that the path survival ratio of the proposed algorithm is approximately two times higher when large number of communication links fails. In addition, we apply the global recovery and local recovery schemes to observe the increase in the overhead message exchanges. Compared to the global recovery scheme, local recovery scheme requires six times less control messages to establish the substitute path when a small number of link failures occur, whereas more than 90% communication paths survive.
<i>Bacillus</i> sp. L324-92 for Biological Control of Three Root Diseases of Wheat Grown with Reduced Tillage (1997)

ABSTRACT Strain L324-92 is a novel Bacillus sp. with biological activity against three root diseases of wheat, namely take-all caused by Gaeumannomyces graminis var. tritici, Rhizoctonia root rot caused by Rhizoctonia solani AG8, and Pythium root rot caused mainly by Pythium irregulare and P. ultimum, that exhibits broad-spectrum inhibitory activity and grows at temperatures from 4 to 40 degrees C. These three root diseases are major yieldlimiting factors for wheat in the U.S. Inland Pacific Northwest, especially wheat direct-drilled into the residue of a previous cereal crop. Strain L324-92 was selected from among approximately 2,000 rhizosphere/rhizoplane isolates of Bacillus species isolated from roots of wheat collected from two eastern Washington wheat fields that had long histories of wheat. Roots were washed, heat-treated (80 degrees C for 30 min), macerated, and dilution-plated on (1)/(10)-strength tryptic soy agar. Strain L324-92 inhibited all isolates of G. graminis var. tritici, Rhizoctonia species and anastomosis groups, and Pythium species tested on agar at 15 degrees C; provided significant suppression of all three root diseases at 15 degrees C in growth chamber assays; controlled either Rhizoctonia root rot, takeall, or both; and increased yields in field tests in which one or more of the three root diseases of wheats were yield-limiting factors. The ability of L324-92 to grow at 4 degrees C probably contributes to its biocontrol activity on direct-drilled winter and spring wheat because, under Inland Northwest conditions, leaving harvest residues of the previous crop on the soil surface keeps soils cooler compared with tilled soils. These results suggest that Bacillus species with desired traits for biological control of wheat root diseases are present within the community of wheat rhizosphere microorganisms and can be recovered by protocols developed earlier for isolation of fluorescent Pseudomonas species effective against take-all.
Mutual Coupling Reduction in Patch Antenna Arrays Using a UC-EBG Superstrate (2010)

Reducing mutual coupling between elements of an antenna array is one of the main topics in array designs. The use of electromagnetic band-gap (EBG) structures built by microstrip technology is an attractive way to mitigate the mutual coupling problem. This letter describes a novel configuration of uniplanar compact electromagnetic band-gap (UC-EBG) structures to reduce mutual coupling between the radiating elements. The idea is to use the UC-EBG structures placed on top of the antenna layer. The main objective is to reduce both the element separation and the mutual coupling between the patch antennas, which in turn increases antenna directivity. The proposed configuration eliminates drawbacks of similar structures presented in previous works.
Object detection by using "whitening/dewhitening" to transform target signatures in multitemporal hyperspectral and multispectral imagery (2003)

Changes in atmosphere, ground conditions, scene temperature, solar illumination, and sensor response can significantly affect the detected multispectral and hyperspectral data. Using uncorrected spectral target signatures in spectral matched filter searches therefore results in target detection with concomitant high false-alarm rates due to changes in multispectral and hyperspectral images. This letter introduces the use of the whitening/dewhitening (WD) transform to help correct target spectral signatures under varying conditions. An important feature of this transform is that it does not require subpixel registration between images collected at two distinct times. The transform was tested on images taken from two very different data collects using different sensors, targets, and backgrounds. In one dataset, the transform was applied to hyperspectral images taken from airborne longwave infrared sensor binned to 30 bands and the other data collect used images of a variety of tanks, trucks, calibration panels that were collected using bore-sighted broadband visible, shortwave infrared, midwave infrared, and longwave infrared staring array sensors. Target spectral signatures were transformed using imagery of spatially overlapping regions from datasets collected at different times and processed using the whitening and then dewhitening transform (inverse of a whitening transform). Use of the WD transform yielded a large target-to-clutter ratio (TCR) and was compared to the TCR derived from other transforms that approximated the cross-covariance matrix. In addition, the WD-transformed signatures applied in a matched filter search found targets (some concealed behind vegetative foliage or underneath camouflage) with low false-alarm rates as shown in a receiver operator characteristic curve. This letter demonstrates that the WD transform enhances searches for concealed targets in multisensor and hyperspectral data.
Biochemical and Pharmacological Properties of SANORG 32701 (1996)

SANORG 32701 is a new sulfated pentasaccharide obtained by total chemical synthesis. It is analogue of the "synthetic pentasaccharide" (SR 90107/ORG 31540), which represents the antithrombin III (AT-III) binding site of heparin. Like SR 90107, it shows high affinity for human AT-III (Kd = 3.7 +/- 0.7 nmol/L) and is a potent catalyst of its inhibitory effect with regard to factor Xa (1100 +/- 31 versus 850 +/- 27 anti-Xa U/mg for SR 90107). SANORG 32701 inhibited thrombin generation occurring via both the extrinsic and intrinsic pathways in vitro. After intravenous or subcutaneous administration to rabbits or rats, SANORG 32701 displayed prolonged anti-factor Xa activity and inhibition of thrombin generation ex vivo. SANORG 32701 was slowly eliminated, showing elimination half-lives between 2.8 and 4.9 hours with different doses. SANORG 32701 displayed antithrombotic activity by virtue of its potentiation of the anti-factor Xa activity of AT-III. It strongly inhibited thrombus formation in an experimental model of thromboplastin-induced venous thrombosis in rats (intravenously) and rabbits (subcutaneously) (ED50 values were 25.5 +/- 4.1 and 91 +/- 12.7 nmol/kg, respectively). SANORG 32701 inhibited the accretion of fibrinogen I 125 to a preformed thrombus in the rabbit jugular vein and significantly reduced thrombus growth occurring after electrical stimulation of the rabbit carotid artery. In the rabbit, intravenous injection of SANORG 32701 enhanced tissue plasminogen activator (TPA)-induced thrombolysis, suggesting that concomitant use of SANORG 32701 during TPA therapy may be helpful in preventing thrombus accretion, thus facilitating clot lysis. In the rat, SANORG 32701 potently inhibited thrombus formation induced on a silk thread in an arteriovenous shunt and in the vena cava. Compared with standard heparin, SANORG 32701 (1000 nmol/kg IV) caused only minimal bleeding enhancement and exhibited a favorable antithrombotic activity/ bleeding risk ratio, therefore showing that it might be considered as a promising compound in the treatment and prevention of various thrombotic diseases.
SearchBots (2018)

Popular messaging platforms such as Slack have given rise to hundreds of chatbots that users can engage with individually or as a group. We present a Wizard of Oz study on the use of searchbots (i.e., chatbots that perform specific types of searches) during collaborative information-seeking tasks. Specifically, we study searchbots that intervene dynamically and compare between two intervention types: (1) the searchbot presents questions to users to gather the information it needs to produce results, and (2) the searchbot monitors the conversation among the collaborators, infers the necessary information, and then displays search results with no additional input from the users. We investigate three research questions: (RQ1) What is the effect of a searchbot (and its intervention type) on participants» collaborative experience' (RQ2) What is the effect of a searchbot»s intervention type on participants» perceptions about the searchbot and level of engagement with the searchbot' and (RQ3) What are participants» impressions of a dynamic searchbot? Our results suggest that dynamic searchbots can enhance users» collaborative experience and that the intervention type does not greatly affect users» perceptions and level of engagement. Participants» impressions of the searchbot suggest unique opportunities and challenges for future work.
Diazotransfer Reagents1 (1996)

The explosive hazard of widely used diazotransfer reagents has been measured. Since no single reagent is suitable for all uses, selection must be based on minimization of hazard and ease of purification of the product. In general, azidotransfer reagents are more energetic than diazotransfer reagents, therefore more hazardous to the researcher. Users of azidotransfer reagents are invited to determine the inherent hazards of these compounds.