gebhart/patrepeval huggingface dataset:
On Cooperative On-Path and Off-Path Caching Policy for Information Centric Networks (ICN) (2016)

Information Centric Networks (ICN) envisions a radical shift from existing host-centric networking of the Internet to a content centric networking. Caching is an important and integral part of ICN. In ICN, the requested contents that are downloaded from the original source are stored at intermediate on-path routers. With increase in similarity in the requests by multiple users, similarity of contents passing through edge routers increases. This leads to cache redundancy at the edge routers resulting in decrease in network performance. To improve the network performance in such kind of scenarios, we have proposed a co-operative caching policy in which the edge routers or on-path routers optimally store the requested ICN contents and are supported by a strategically placed central off-path cache router for additional level of caching. We have proposed a simple heuristic mechanism which can be used to offload and to optimally store the contents from the on-path routers to off-path central cache router. Through theoretical studies and simulations we have demonstrated that this cooperative scheme improves the performance of the network significantly in terms of cache duplication, delay and network usage. While we have presented the results for a typical campus network, similar results can be expected in larger Internet by clustering a group of on-path routers around some criterion and then allocating an off-path cache router at a nearby location to the on-path routers.
AUTOCRINE REGULATION OF CASEIN TURNOVER IN GOAT MAMMARY EXPLANTS (1988)

Local feedback control of milk protein secretion was investigated in goat mammary explants by measuring degradation of newly synthesized casein in the presence of a goat milk whey fraction. Reduced net synthesis of [3H]casein in the presence of the milk fraction was due, at least in part, to its degradation during secretion, suggesting that this process is under autocrine regulation.
A Non-Contact Waveguide Probe for On-Wafer <formula formulatype="inline"><tex Notation="TeX">$S$</tex></formula>-Parameter Measurements for Submillimeter-Wave to Terahertz Band (2014)

This paper presents a non-contact on-wafer S- parameter measurement method for submillimeter-wave and terahertz frequency range. The proposed method is based on using open-ended waveguide probes along with on-wafer waveguide transitions to measure the S-parameters of waveguide based components and devices. To enable non-contact measurements, an RF choke is designed and machined on the metallic cross section of the probes using electric discharge machining. Additionally, to enhance the accuracy and repeatability of the measurements, a probe aligner is micromachined over the on-wafer transition. In order to validate the measurement concept, a full-band transition operating at J-band (220-325 GHz) is designed and tested. To achieve high accuracy, the fabrication of the on-wafer waveguide and the transition is performed using silicon micromachining. It is shown that the designed back-to-back transition has a return loss of better than 15 dB and an insertion loss of less than 0.2 dB over the entire frequency band. The measurement results of the fabricated transition also show a good agreement with the simulated results.
Applications of molecular replacement to G protein-coupled receptors (2013)

G protein-coupled receptors (GPCRs) are a large class of integral membrane proteins involved in regulating virtually every aspect of human physiology. Despite their profound importance in human health and disease, structural information regarding GPCRs has been extremely limited until recently. With the advent of a variety of new biochemical and crystallographic techniques, the structural biology of GPCRs has advanced rapidly, offering key molecular insights into GPCR activation and signal transduction. To date, almost all GPCR structures have been solved using molecular-replacement techniques. Here, the unique aspects of molecular replacement as applied to individual GPCRs and to signaling complexes of these important proteins are discussed.
Automatic code generation and data management for an asynchronous task-based runtime (2016)

Hardware scaling and low-power considerations associated with the quest for exascale and extreme scale computing are driving system designers to consider new runtime and execution models such as the event-driven-task (EDT) models that enable more concurrency and reduce the amount of synchronization. Further, for performance, productivity, and code sustainability reasons, there is an increasing demand for auto-parallelizing compiler technologies to automatically produce code for EDT-based runtimes. However achieving scalable performance in extreme-scale systems with auto-generated codes is a non-trivial challenge. Some of the key requirements that are important for achieving good scalable performance across many EDT-based systems are: (1) scalable dynamic creation of task-dependence graph and spawning of tasks, (2) scalable creation and management of data and communications, and (3) dynamic scheduling of tasks and movement of data for scalable asynchronous execution. In this paper, we develop capabilities within R-Stream - an automatic source-to-source optimization compiler - for automatic generation and optimization of code and data management targeted towards Open Community Runtime (OCR) - an exascale-ready asynchronous task-based runtime. We demonstrate the effectiveness of our techniques through performance improvements on various benchmarks and proxy application kernels that are relevant to the extreme-scale computing community.
Identification and Biological Activities of New Taccalonolide Microtubule Stabilizers (2011)

The taccalonolides are a unique class of microtubule stabilizers that do not bind directly to tubulin. Three new taccalonolides, Z, AA, and AB, along with two known compounds, taccalonolides R and T, were isolated from Tacca chantrieri and Tacca integrifolia. Taccalonolide structures were determined by 1D and 2D NMR methods. The biological activities of the new taccalonolides, as well as taccalonolides A, B, E, N, R, and T, were evaluated. All nine taccalonolides display microtubule stabilizing activity, but profound differences in antiproliferative potencies were noted, with IC(50) values ranging from the low nanomolar range for taccalonolide AA (32 nM) to the low micromolar range for taccalonolide R (13 μM). These studies demonstrate that diverse taccalonolides possess microtubule stabilizing properties and that significant structure-activity relationships exist. In vivo antitumor evaluations of taccalonolides A, E, and N show that each of these molecules has in vivo antitumor activity.
Rounding Arrangements Dynamically (1998)

We describe a robust, dynamic algorithm to compute the arrangement of a set of line segments in the plane, and its implementation. The algorithm is robust because, following Greene 7 and Hobby, 11 it rounds the endpoints and intersections of all line segments to representable points, but in a way that is globally topologically consistent. The algorithm is dynamic because, following Mulmuley, 16 it uses a randomized hierarchy of vertical cell decompositions to make locating points, and inserting and deleting line segments, efficient. Our algorithm is novel because it marries the robustness of the Greene and Hobby algorithms with Mulmuley's dynamic algorithm in a way that preserves the desirable properties of each.
Highly bendable and effectively single-mode all-solid photonic bandgap fiber with large effective area (2012)

Highly bendable large-mode-area all-solid photonic bandgap fibers for high-power fiber lasers are reported. A 712-μm2 effective area, effectively single-mode operation, and bending loss of less than 0.1 dB/m at a 10-cm bending radius are achieved.
Dynamic Regeneration of Workflow Specification with Access Control Requirements in MANET (2006)

Distributed software systems are the basis for innovative applications. The key for achieving survivable and maintainable distributed systems is agility because the nondeterministic nature of distribution would otherwise leave the system uncontrollable, especially in emerging mobile ad-hoc networks. A mobile ad-hoc network (MANET) is based on a self-organizing and rapidly deployed network of mobile services to collaborate without using any pre-existing fixed network infrastructure. Survivability is defined as the capability of a service to fulfill its mission in a timely manner, even in the presence of attacks, failures, or accidents. There are four key survivability properties: resistance, recognition, recovery and adaptation. Recovery, a hallmark of survivability, is the capability to maintain critical components and resource during attack, limit the extent of damage, and restore full services following attack. Exception handling is a way to deals with the recovery aspect of survivability. Resistance can be viewed as the process of limiting access to critical and vulnerable resources only to authorized users, programs, processes, or other systems. This paper bridges the analysis of secure business process and its recovery aspect in terms of exception handling in the context of access control requirements. We propose an integrated approach to engineer a survivable distributed system through dynamic regeneration of workflow specifications in the context of Business Process Execution Language for Web Services (BPEL) and eXtensible Access Control Markup Language (XACML).
Cutting With High-Pressure Ammonia Jets for Demilitarization of Chemical Weapons (2002)

This paper presents a study on using high-pressure ammonia and abrasive ammonia jets for cutting and washout of chemical weapons. The work focused on chemical rocket M55 simulants. A test chamber was built to cut M60 training and M61 practice rockets at Redstone Arsenal by Teledyne-Commodore who developed a complete destruction process using alkali metals dissolved in anhydrous ammonia to form the aggressive solvated electron technology (SET™) solution. The rocket is loaded in a rotary chuck and stationary cutting/piercing nozzles were used to cut and drill through the rocket. This approach was found to be effective due to minimizing the number of moving parts. High-pressure direct drive and intensifier pumps were developed for this application. It was found that intensifier-based pumps are more suitable for robust field use. The abrasive ammonia jets performed well for cutting the rocket metal shell (aluminum and steel) casing as well as the outside fiberglass case. A wash-out-ammonia jet lance has also been found to completely wash out the simulant materials. Over 20 rockets were successfully cut by Teledyne personnel without any incidents. It was concluded that the use of anhydrous ammonia has numerous advantages over conventional water for chemical weapon demilitarization applications.
An ultra-compact Marx-type high-voltage generator (2002)

This paper discusses the design of an ultra-compact, Marx-type, high-voltage generator. This system incorporates high-performance components that are closely coupled and integrated into an extremely compact assembly. Low profile, custom ceramic capacitors with coplanar extended electrodes provide primary energy storage. Low-inductance, spark-gap switches incorporate miniature gas cavities imbedded within the central region of the annular shaped capacitors, with very thin dielectric sections separating the energy storage capacitors. Carefully shaped electrodes and insulator surfaces are used throughout to minimize field enhancements, reduce fields at triple-point regions, and enable operation at stress levels closer to the intrinsic breakdown limits of the dielectric materials. Specially shaped resistors and inductors are used for charging and isolation during operation. Forward-coupling ceramic capacitors are connected across successive switch-capacitor-switch stages to assist in switching. Pressurized SF/sub 6/ gas is used for electrical insulation in the spark-gap switches and throughout the unit. The pressure housing is constructed entirely of dielectric materials, with segments that interlock with the low-profile switch bodies to provide an integrated support structure for all of the components. This ultra-compact Marx generator employs a modular design that can be sized as needed for a particular application. Units have been assembled with 4, 10, and 30 stages and operated at levels up to 100 kV per stage.
Recent progress in the development of INCITS W1.1: appearance-based image quality standards for printers (2007)

In September 2000, INCITS W1 (the U.S. representative of ISO/IEC JTC1/SC28, the standardization committee for office equipment) was chartered to develop an appearance-based image quality standard.<sup>(1),(2)</sup> The resulting W1.1 project is based on a proposal<sup>(4)</sup> that perceived image quality can be described by a small set of broad-based attributes. There are currently five <i>ad hoc</i> teams, each working towards the development of standards for evaluation of perceptual image quality of color printers for one or more of these image quality attributes. This paper summarizes the work in progress of the teams addressing the attributes of Macro-Uniformity, Color Rendition, Text and Line Quality and Micro-Uniformity.
Construction and Decoding of Product Codes with Non-Systematic Polar\n Codes (2019)

Product codes are widespread in optical communications, thanks to their high\nthroughput and good error-correction performance. Systematic polar codes have\nbeen recently considered as component codes for product codes. In this paper,\nwe present a novel construction for product polar codes based on non-systematic\npolar codes. We prove that the resulting product code is actually a polar code,\nhaving a frozen set that is dependent on the frozen sets of the component polar\ncodes. We propose a low-complexity decoding algorithm exploiting the dual\nnature of the constructed code. Performance analysis and simulations show high\ndecoding speed, that allows to construct long codes while maintaining low\ndecoding latency. The resulting high throughput and good error-correction\nperformance are appealing for optical communication systems and other systems\nwhere high throughput and low latency are required.\n
Range extension of passive wake-up radio systems through energy harvesting (2013)

Use of a passive wake-up radio can drastically increase the network lifetime in a sensor network by reducing or even completely eliminating unnecessary idle listening. A sensor node with a wake-up radio receiver (WuRx) can operate in an extremely low power sleep mode until it receives a trigger signal sent by a wake-up radio transmitter (WuTx). After receiving the trigger signal, the attached WuRx wakes up the sensor node to start the data communication. In this paper, we implement and compare the performance of three passive wake-up radio-based sensor nodes: 1) WISP-Mote, which is a sensor mote that employs an Intel WISP passive RFID tag as the WuRx; 2) EH-WISP-Mote, which combines a novel energy harvester with the WISP-Mote; and 3) REACH-Mote, which uses the energy harvester circuit combined with an ultra-low-power pulse generator to trigger the wake-up of the mote. Experimental results show that the wake-up range and wake-up delay for the EH-WISP-Mote are improved compared with the WISP-Mote, while providing the ability to perform both broadcast-based and ID-based wake-ups. On the other hand, the REACH-Mote, which can only provide broadcast-based wake-up, can achieve a much longer wake-up range than any known passive wake-up radio to date, achieving feasible wake-up at a range of up to 37 ft.
The measurement of optical properties of a multiple scattering medium based on diffused photon pair density wave (2003)

A photon pair density wave (PPDW) is initiated and compared with the conventional defused photon density wave (DPDW) to verify its optical properties generated by correlated parallel polarized pair photons propagating in a scattering medium. An optical heterodyne signal is generated by the scattered correlated pair photons in the scattering medium. However, the phase delay of the signal depends upon the beat frequency and the distance between source and detector. This is similar to DPDW at the lower modulated frequency of laser source in frequency domain. Spherical wave fronts of constant attenuated intensity and the phase delay of PPDW are observed in a homogenous scattering medium by using a lock-in amplifier. The assumption that polarized photon pairs propagating as photon density wave in a multiple scattering medium is verified experimentally. Optical properties of PPDW in the scattering medium are demonstrated successfully.
A wide dynamic range CMOS image sensor with dual charge storage in a pixel and a multiple sampling technique (2008)

This paper presents a dynamic range expansion technique of CMOS image sensors with dual charge storage in a pixel and multiple exposures. Each pixel contains two photodiodes, PD1 and PD2 whose sensitivity can be set independently by the accumulation time. The difference of charge accumulation time in both photodiode can be manipulated to expand the dynamic range of the sensor. It allows flexible control of the dynamic range since the accumulation time in PD2 is adjustable. The multiple exposure technique used in the sensor reduces the motion blur in the synthesized wide dynamic range image when capturing fast-moving objects. It also reduces the signal-to-nose ratio dip at the switching point of the PD1 signal to the PD2 signals in the synthesized wide dynamic range image. A wide dynamic range camera with 320x240 pixels image sensor has been tested. It is found that the sampling of 4 times for the short accumulation time signals is sufficient for the reduction of motion blur in the synthesized wide dynamic range image, and the signal-to-noise ratio dip at the switching point of the PD1 signal to the PD2 signal is improved by 6 dB using 4 short-time exposures.
Siloxane containing addition polyimides. II - Acetylene terminated polyimides (1984)

Acetylene terminated polyimide oligomers having a range of molecular weights have been synthesized by reacting bis (gamma-aminopropyl) tetramethyldisiloxane, aminophenylacetylene and 3, 3', 4, 4' benzophenonetetracarboxylic dianhydride in different molar ratios. The prepolymers were isolated and characterized for melt flow and cure properties. They show promise as adhesives for bonding titanium to titanium and as matrix resins for graphite cloth reinforced composites. The most promising system has been blended in varying proportions with Thermid 600, a commercially available acetylene terminated polyimide oligomer, and the mixtures have been tested for application as composite matrix resins.
Effect of statin on age-related hearing loss via drug repurposing (2022)

Hearing loss in the elderly cause communication difficulties, decreased quality of life, isolation, loneliness and frustration. The aim of our study was to investigate the effect of drug repurposing candidates in aging mouse. The selected candidate drugs for age-related hearing loss (ARHL) included atorvastatin (AS) and sarpogrelate. Monotherapy or fixed dose combination (FDC) products were administered via oral gavage for 6 consecutive months. Auditory outcomes showed significant hearing preservation in AS-treated aging mice compared to aging control, especially in the early stages of ARHL in both 8 and 16 kHz frequencies. However, none of the FDC products were able to prevent ARHL regardless of AS involvement. In aging mice, damage and dysfunction of mitochondria was noted as well as reactive oxygen species overproduction leading to oxidative stress and intrinsic apoptosis. These processes of ARHL were significantly prevented with administration of AS. Normal structures of mitochondria were maintained, and antioxidant activity were proceeded by activation of HSF1/Sirt1 pathway. Our study suggests that AS is a promising drug repurposing candidate to delay the progression of ARHL.
Three-Dimensional Imaging and Processing Using Computational Holographic Imaging (2006)

Digital holography is a technique that permits digital capture of holograms and subsequent processing on a digital computer. This paper reviews various applications of this technique. The presented applications cover three-dimensional (3-D) imaging as well as several associated problems. For the case of 3-D imaging, optical and digital methods to reconstruct and visualize the recorded objects are described. In addition, techniques to compress and encrypt 3-D information in the form of digital holograms are presented. Lastly, 3-D pattern recognition applications of digital holography are discussed. The described techniques constitute a comprehensive approach to 3-D imaging and processing.
Digital-carrier multi-band user codes for baseband UWB multiple access (2003)

The growing interest towards ultra-wideband (UWB) communications stems from its unique features such as baseband operation, ample multipath diversity, and the potential of enhanced user capacity. But since UWB has to overlay existing narrowband systems, multiple access has to be achieved in the presence of narrowband interference (NBI). However, existing baseband spreading codes for UWB multiple access are not flexible in handling NBI. In this paper, we introduce two novel spreading codes that not only enable baseband UWB multiple access, but also facilitate flexible NBI cancellation. We construct our codes using a single carrier or multiple carriers (SC or MC), which can be implemented with standard discrete-cosine transform (DCT) circuits. With our SC/MC codes, NBI can be avoided by simply nulling undesired digital carriers. Being digital, these SC/MC codes give rise to multi-band UWB systems, without invoking analog carriers. In addition, our SC/MC codes enable full multipath diversity, and maximum coding gains. Equally attractive is their capability to reduce the number of interfering users, with simple matched filter operations. Comprehensive simulations are also carried out to corroborate our analysis.
ChemInform Abstract: ANTICONVULSIVA 1. MITT. ALKOXYMETHYL‐DERIVATE VON BARBITURATEN UND DIPHENYLHYDANTOIN 2. MITT. ACYLOXYMETHYL‐ UND HALOGENMETHYL‐DERIVATE VON BARBITURSAEURE UND DIPHENYLHYDANTOIN (1971)

Abstract Alkoxymethyl‐, Acyloxymethyl‐ und Halogenmethyl‐Derivate von Barbitursäuren oder Diphenylhydantoin stellen wirksame Anticonvulsiva dar, deren pharmakologisches Verhalten untersucht wird.
Coherent electromagnetic field imaging through Fourier transform heterodyne (1998)

The authors present a detection process capable of directly imaging the transverse amplitude, phase, and if desired, Doppler shift of coherent electromagnetic fields. Based on coherent detection principles governing conventional heterodyned RADAR/LIDAR systems, Fourier Transform Heterodyne (FTH) incorporates transverse spatial encoding of the local oscillator for image capture. Appropriate selection of spatial encoding functions, or basis set, allows image retrieval by way of classic Fourier manipulations. Of practical interest: (1) imaging is accomplished on a single element detector requiring no additional scanning or moving components, and (2) a wide variety of appropriate spatial encoding functions exist that may be adaptively configured in real-time for applications requiring optimal detection. In this paper, they introduce the underlying principles governing FTH imaging, followed by demonstration of concept via a simple experimental setup based on a HeNe laser and a 69 element spatial phase modulator.
Synthesis of (±)-benzoleukotriene B<sub>3</sub>: a novel leukotriene B<sub>4</sub>analogue (1989)

As part of a program to identify therapeutically effective leukotriene B4-antagonists, we have synthesized benzoleukotriene B3 in which the Z-6,7 double bond of LTB4 has been replaced by a phenyl group. The synthesis relies heavily on palladium(0)-mediated vinylstannane/vinyl halide coupling reactions.