gebhart/patrepeval huggingface dataset:
Sponsored Search Auction Considering Combinational Bids with Externalities (2015)

Sponsored search is a mechanism that shows the appropriate ads according to search queries. The orders and payments of ads are determined by the auction. Recently, the allocations are determined by the click through rate(CTR) and the externalities which give effects to CTR and haven't been considered in existing works. However, the mechanism with externalities has high computational cost. The algorithm which can calculate the approximated solution considering the externalities within the polynomial-time are proposed, however, it assumed that one bidder can propose only a single ad. In this paper, we propose the approximation allocation algorithm that one bidder can offer many ads considering externalities. The proposed algorithm employs the concept of the combinatorial auction in order to consider the combinational bids. In addition, the proposed algorithm can find the approximated allocation by the dynamic programming. Moreover, we prove the computational complexity and the monotonicity of the proposed mechanism, and demonstrate computational costs and efficiency ratios by changing the number of ads, slots and maximum bids. The experimental results show that the proposed algorithm can calculate 0.7-approximation solution even though the full search can't find solutions in the limited times.
The flying monkey: A mesoscale robot that can run, fly, and grasp (2016)

The agility and ease of control make a quadrotor aircraft an attractive platform for studying swarm behavior, modeling, and control. The energetics of sustained flight for small aircraft, however, limit typical applications to only a few minutes. Adding payloads - and the mechanisms used to manipulate them - reduces this flight time even further. In this paper we present the flying monkey, a novel robot platform having three main capabilities: walking, grasping, and flight. This new robotic platform merges one of the world's smallest quadrotor aircraft with a lightweight, single-degree-of-freedom walking mechanism and an SMA-actuated gripper to enable all three functions in a 30 g package. The main goal and key contribution of this paper is to design and prototype the flying monkey that has increased mission life and capabilities through the combination of the functionalities of legged and aerial robots.
Priority inversion in multi processor systems due to protected actions (2005)

The use of multiple processors give rise to new issues regarding old problems of the Ada95 design.In this paper we discuss how serviceing of protected actions, due to unspecified dispatching, can lead to unbounded priority inversion in systems with multiple processors. We also discuss different ways to resolve the problem.
Effiecient WZ-to-H264 transcoding using motion vector information sharing (2009)

In mobile-to-mobile video communications, both the sender and the receiver devices should not have higher complexity requirements to perform complex video compression tasks. The traditional video coding solutions are not suitable to support this communications due to its extremely complex encoding algorithm. On the other hand, the new Wyner-Ziv video coding paradigm reduces the complexity of the encoder at the expenses of a more complex decoder. In this paper, we propose an improved WZ/H.264 video transcoder to support this mobile-to-mobile communications, using the low complexity Wyner-Ziv encoding and the traditional H.264 decoding to be implemented in the end-user devices. The improved transcoder converts the video from the Wyner-Ziv to H.264 and reuses the motion vectors generated in the Wyner-Ziv decoding, in order to reduce the computational complexity of the motion estimation process in the H.264 encoding. Simulations results show a complexity reduction up to 55% with negligible rate-distortion drop.
Machine Learning-Based Classification of Human Behaviors and Falls in Restroom via Dual Doppler Radar Measurements (2022)

This study presents a radar-based remote measurement system for classification of human behaviors and falls in restrooms without privacy invasion. Our system uses a dual Doppler radar mounted onto a restroom ceiling and wall. Machine learning methods, including the convolutional neural network (CNN), long short-term memory, support vector machine, and random forest methods, are applied to the Doppler radar data to verify the model's efficiency and features. Experimental results from 21 participants demonstrated the accurate classification of eight realistic behaviors, including falling. Using the Doppler spectrograms (time-velocity distribution) as the inputs, CNN showed the best results with an overall classification accuracy of 95.6% and 100% fall classification accuracy. We confirmed that these accuracies were better than those achieved by conventional restroom monitoring techniques using thermal sensors and radars. Furthermore, the comparison results of various machine learning methods and cases using each radar's data show that the higher-order derivative parameters of acceleration and jerk, and the motion information in the horizontal direction are the efficient features for behavior classification in a restroom. These findings indicate that daily restroom monitoring using the proposed radar system accurately recognizes human behaviors and allows early detection of fall accidents.
Comparison of texture features based on Gabor filters (2003)

The performance of a number of texture feature operators is evaluated. The features are all based on the local spectrum which is obtained by a bank of Gabor filters. The comparison is made using a quantitative method which is based on Fisher's criterion. It is shown that, in general, the discrimination effectiveness of the features increases with the amount of post-Gabor processing.
Host Restriction Factors Blocking Retroviral Replication (2008)

Retroviruses are highly successful intracellular parasites, and as such they are found in nearly all branches of life. Some are relatively benign, but many are highly pathogenic and can cause either acute or chronic diseases. Therefore, there is tremendous selective pressure on the host to prevent retroviral replication, and for this reason cells have evolved a variety of restriction factors that act to inhibit or block the viruses. This review is a survey of the best-characterized restriction factors capable of inhibiting retroviral replication and aims to highlight the diversity of strategies used for this task.
Linking Sequences of Active Appearance Sub-Models via Constraints: An Application in Automated Vertebral Morphometry (2003)

Statistical models of shape and appearance are powerful tools for interpreting medical and other images. However there can remain problems with under-trained models being too constrained. We have combined a global model with a sequence of partially overlapping sub-models, in a manner that exploits all the statistical information, whilst mitigating the under-training problem. Instead of applying one global model, we use a global model to apply iteratively-updated soft constraints on a sequence of sub-models. These sub-models may also partially overlap, and thus previously fit sub-models can also impose soft constraints on the next iteration. The algorithm has been applied to dual x-ray absorptiometry scans of the spine in order to automate vertebral morphometry measurements, using overlapping triplets of vertebrae as the sub-models, together with a global model of the entire spine. Combining a global model in this way with a sequence of sub-models gives substantially better results than using the former alone.
[Detection of amplified DNA sequences by comparative genomic in situ hybridization with human glioma tumor DNA as probe]. (1994)

Comparative genomic hybridization (CGH) provides a new possibility for the investigation of genetic alterations in tumour genomes. In our experiments CGH was carried out using genomic DNA from human glioblastoma multiforme (GBM) as a probe for chromosomal in situ suppression hybridization. Amplified DNA sequences contained in the tumour DNA showed specific signals, revealing the chromosomal positions of these sequences. Using this approach we detected amplifications of different chromosomal segments in individual GBM specimens. In accordance with the results from Southern analysis demonstrating amplification of the EGFR gene in 45% of human GBM, CGH signals in different GBM mapped to the region of this gene on chromosome 7p. Other signals detected by CGH involved chromosome 12q and 8q. Our data demonstrate CGH as a novel comprehensive and rapid approach for the analysis of complex genomic alterations in glial tumours.
The Demand for Wine Tourism in Canyon County, Idaho (2004)

Many commercial wineries produce a dual product: commercial wine and wine tourism. Since Idaho wineries charge no entry price, wine tourism demand can only be ascertained with a shadow price for winery visitation. Demand for wine tourism visits for Canyon County in southern Idaho was estimated using the travel cost method. Trip demand was inelastic (-0.4 to -0.6) with respect to own price. The average value of Canyon County wine tourism ranged from $6 to $12 per person per trip, depending upon the assumed opportunity cost of travel time. Elasticities of tastes and preferences, closely related goods, and income were estimated with a view to understanding the market for Idaho's emerging wine tourism industry.
Kinetoplastids: related protozoan pathogens, different diseases (2008)

Kinetoplastids are a group of flagellated protozoans that include the species Trypanosoma and Leishmania, which are human pathogens with devastating health and economic effects. The sequencing of the genomes of some of these species has highlighted their genetic relatedness and underlined differences in the diseases that they cause. As we discuss in this Review, steady progress using a combination of molecular, genetic, immunologic, and clinical approaches has substantially increased understanding of these pathogens and important aspects of the diseases that they cause. Consequently, the paths for developing additional measures to control these "neglected diseases" are becoming increasingly clear, and we believe that the opportunities for developing the drugs, diagnostics, vaccines, and other tools necessary to expand the armamentarium to combat these diseases have never been better.
Chronic Over-expression of Fibroblast Growth Factor 21 Increases Bile Acid Biosynthesis by Opposing FGF15/19 Action (2016)

Pharmacological doses of fibroblast growth factor (FGF) 21 effectively normalize glucose, lipid and energy homeostasis in multiple animal models with many benefits translating to obese humans with type 2 diabetes. However, a role for FGF21 in the regulation of bile acid metabolism has not been reported. Herein, we demonstrate AAV-mediated FGF21 overexpression in mice increases liver expression of the key bile acid producing enzyme, Cyp7a1, resulting in an increased bile acid pool. Furthermore, in cholecystectomized mice, FGF21-mediated bile acid pool increase led to increased transit of bile acids into colon. We elucidate that the mechanism of FGF21 induced bile acid changes is mainly through antagonizing FGF15/19 function on liver βKlotho/FGFR4 receptor complex; thus inhibiting FGF15/19-mediated suppression of Cyp7a1 expression. In conclusion, these data reveal a previously unidentified role for FGF21 on bile acid metabolism and may be relevant to understand the effects of FGF21 analogs in clinical studies.
Isoursodeoxycholic acid: metabolism and therapeutic effects in primary biliary cirrhosis (2001)

Significant amounts of ursodeoxycholic acid (UDCA) used for the treatment of patients with primary biliary cirrhosis (PBC) become epimerized at C-3 to isoUDCA. We investigated the metabolism of isoUDCA and a possible pharmacologic effect in five patients (51.4 +/- 5.8 years old; 3 females, 2 males) with PBC and persistent elevations of gamma-glutamyl transpeptidase (gamma-GT) and alkaline phosphatase despite treatment with UDCA for more than one year. Serum samples were analyzed for bile acid metabolites and surrogate markers of cholestasis in 4-week intervals after 1 g/d UDCA, wash-out, 0.5 g/d isoUDCA, 0.75 g/d isoUDCA, 0.75 g/d UDCA, and two further periods with 1 g/d UDCA. Bile acids in urine were analyzed after wash-out, 0.5 and 0.75 g/d isoUDCA, and 0.75 and 1 g/d UDCA. During wash-out, AST, AP, and gamma-GT rose significantly (P < 0.05) but reversed to previous levels during the first isoUDCA period, with 0.5 g/d only. No further improvements were observed after increasing the dose of isoUDCA or switching back to UDCA. In serum, the relative amounts of isoUDCA and UDCA were 8.1 +/- 7.4% and 16.2 +/- 6.4% during 0.5 g/d isoUDCA, 6.2 +/- 2.5% and 45.0 +/- 4.1% during 0.75 g/d isoUDCA, and 0.5;-3% and 56.4;-60.0%, respectively, during UDCA. In urine, UDCA was the predominant bile acid both during isoUDCA and UDCA medications. The similar serum enrichment and urinary excretion of UDCA during administration of either isoUDCA or UDCA together with low concentrations of the intermediate of isomerization, 3-dehydro-UDCA, indicate a first-pass epimerization of isoUDCA to UDCA in the liver. Approximately 25% of serum isoUDCA and 10% of serum UDCA were conjugated with either glucuronic acid or N-acetylglucosamine, indicating hepatic formation and systemic secretion of glycosidic conjugates. In PBC patients, isoUDCA becomes isomerized to UDCA and has similar effects on surrogate markers of cholestasis. Thus, isoUDCA has pro-drug characteristics.
Desigualdades sociales y enfermedades infecciosas emergentes (2001)

Americanae nace como un proyecto conjunto que surge dentro de la Red Europea de Información y Documentación sobre América Latina (REDIAL), y que ha afrontado la Biblioteca de la Agencia Española de Cooperación Internacional para el Desarrollo (AECID). Esta nueva biblioteca virtual hace más accesibles los libros digitales de tema americanista a los investigadores y usuarios interesados de cualquier parte del mundo.
Early postoperative complications after coronary artery bypass grafting at the Cardiovascular Center of Puerto Rico and the Caribbean. (1998)

CABG is being performed with an acceptably low complication rate in this institution.
Bone Mineral Density T-Scores Derived from CT Attenuation Numbers (Hounsfield Units): Clinical Utility and Correlation with Dual-energy X-ray Absorptiometry. (2018)

Although lumbar trabecular HU T-scores are lower than DXA T-scores, thresholds can be selected to achieve high sensitivity and specificity when screening for osteoporosis. Patients with a lumbar T-score<sub>HU</sub> ≤ -3.0 should be referred for additional evaluation. Further research into HU T-scores and clinical correlates may also provide a tool to assess changes in vertebral bone and the relationship to fracture risk across the lifespan.
Solid-Phase Epitaxial Crystallization of Strain-Relaxed<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">Si</mml:mi></mml:mrow><mml:mrow><mml:mn>1</mml:mn><mml:mo>−</mml:mo><mml:mi>x</mml:mi></mml:mrow></mml:msub></mml:mrow><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">Ge</mml:mi></mml:mrow><mml:mrow><mml:mi>x</mml:mi></mml:mrow></mml:msub></mml:mrow></mml:math>Alloy Layers (1994)

Solid-phase epitaxial crystallization (SPEC) of Si, Ge, and strain-relaxed ${\mathrm{Si}}_{1\ensuremath{-}x}{\mathrm{Ge}}_{x}$ alloys, with $x$ in the range 0.11 to 0.53, is investigated in the temperature range 300 to 650\ifmmode^\circ\else\textdegree\fi{}C. The activation energy for SPEC is shown not to vary monotonically with increasing Ge concentration but to increase above that of Si for Ge concentrations less than $x\ensuremath{\le}0.4$. This unexpected behavior is discussed in terms of existing models for SPEC.
Furosemide Reduces the Incidence of Pulmonary Hypertension Syndrome (Ascites) in Broilers Exposed to Cool Environmental Temperatures (1995)

The incidence of pulmonary hypertension syndrome (PHS; ascites) was evaluated in two experiments using broiler breeder male by-product chicks exposed after 3 wk of age to cool environmental temperatures (10 to 15 C). In Experiment 1, 3- to 6-wk-old birds were fed a grower diet to which 0 (Control), .001, .005, .010, or .015% furosemide had been added. All groups in Experiment 1 were fed a finisher ration containing no furosemide during Weeks 7 to 8. In Experiment 2, the Control group received no furosemide, a second group received .015% furosemide during the grower phase only (Weeks 3 to 6), and the third group received .015% furosemide during the grower and finisher phases (Weeks 3 to 8). Cumulative PHS mortality was significantly reduced by furosemide in both experiments. Compared with Controls, birds fed .015% furosemide did not have lower (P = .077) final body weights in Experiment 1 but did have significantly lower final body weights in Experiment 2. Lower levels of furosemide significantly reduced PHS mortality without reducing body weights. Furosemide did not improve feed conversion in either experiment. Neither body weight on Day 1 or 21 nor net Day 1 to 21 weight gain were predictive of susceptibility to PHS during the subsequent grower and finisher intervals in either experiment. On Day 55 of Experiment 2, large healthy birds fed .015% furosemide had significantly lower right:total ventricular weight ratios than control birds, indicating that furosemide reduced right ventricular hypertrophy, presumably by reducing pulmonary arterial pressure.
Lumateperone-mediated effects on prefrontal glutamatergic receptor-mediated neurotransmission: A dopamine D1 receptor dependent mechanism (2022)

Lumateperone is a novel drug approved for the treatment of schizophrenia in adults and depressive episodes associated with bipolar depression in adults, as monotherapy and as adjunctive therapy with lithium or valproate treatment in the United States. Lumateperone simultaneously modulates key neurotransmitters, such as serotonin, dopamine, and glutamate, implicated in serious mental illness. In patients with schizophrenia, lumateperone was shown to improve positive symptoms along with negative and depressive symptoms, while also enhancing prosocial behavior. Moreover, in patients with bipolar I or II disorder, lumateperone improved depressive symptoms as well. To further understand the mechanisms related to lumateperone's clinical response, the aim of this study was to investigate the effect of lumateperone on dopaminergic- and glutamatergic signaling in the rat medial prefrontal cortex (mPFC). We used the conditioned avoidance response (CAR) test to determine the antipsychotic-like effect of lumateperone, electrophysiology in vitro to study lumateperone's effects on NMDA- and AMPA-induced currents in the mPFC, and the neurochemical techniques microdialysis and amperometry to measure dopamine- and glutamate release in the rat mPFC. Our results demonstrate that lumateperone; i) significantly suppressed CAR in rats, indicating an antipsychotic-like effect, ii) facilitated NMDA and AMPA receptor-mediated currents in the mPFC, in a dopamine D<sub>1</sub>-dependent manner, and iii) significantly increased dopamine and glutamate release in the rat mPFC. To the extent that these findings can be translated to humans, the ability of lumateperone to activate these pathways may contribute to its demonstrated effectiveness in safely improving symptoms related to neuropsychiatric disorder including mood alterations.
Increased number of substance P positive nerve fibres in interstitial cystitis (1995)

SP, a neuropeptide secreted from sensory nerve endings, has been implicated in the pathophysiology of pain and has been shown to trigger MC secretion. Moreover, MC secretion by SP is augmented by oestradiol and bladder MCs have been shown to express high affinity oestrogen receptors. A functional relationship between SP and MCs may explain the pathophysiology of the neuro-inflammatory and painful nature of IC.
Sentiment Lexicon Interpolation and Polarity Estimation of Objective and Out-Of-Vocabulary Words to Improve Sentiment Classification on Microblogging (2014)

conference paper
Detection and Mitigation of Cross-Correlation Interference in High-Sensitivity GNSS Receivers (2007)

This paper presents the architecture of a GPS receiver suitable for indoor operation with extremely weak signals. The receiver works in acquisition-only mode, and combines coherent and long non-coherent correlations in order to achieve low sensitivity. It is confirmed by processing simulated and live GPS signals that this kind of receivers must have the capability to detect and mitigate near-far interference. Novel near-far detection and mitigation techniques are proposed. The new detector is based on the different statistics of the two largest cross-correlation peaks in the presence and in the absence of near-far interference, and it outperforms previously proposed detectors in terms of (mis)detection probability and complexity. The mitigation technique is based on the concepts of successive interference cancellation and subspace projection. It is also novel the fact that, according to the proposed receiver architecture, the near-far mitigation technique is only applied selectively, when the detector has found some interfered signals and the interfering signals have been identified. This reduces the computational complexity without any performance penalty, compared to previously proposed techniques that eliminate the contribution of all potentially (but not necessarily) interfering signals.
Optical properties of a-Si and a-Si:H prepared by DC magnetron techniques (1983)

The authors investigate the optical properties of amorphous silicon and hydrogenated amorphous silicon films prepared by DC magnetron reactive sputtering and by glow-discharge techniques. Optical constants n and k are determined for six films over the wavelength range 0.4-2.5 mu m (photon energy range 0.5-3.1 eV) and are used to obtain the optical band gaps, density-of-states constant, and the width of the Urbach tail of the bands. The authors investigate the effect of a small percentage of metal additives on the optical properties of the materials, and the effect of heat treatment on hydrogenated material.
Photoelectrochemistry of core–shell tandem junction n–p<sup>+</sup>-Si/n-WO<sub>3</sub>microwire array photoelectrodes (2013)

Tandem junction (n–p+-Si/ITO/WO3/liquid) core–shell microwire devices for solar-driven water splitting have been designed, fabricated and investigated photoelectrochemically. The tandem devices exhibited open-circuit potentials of Eoc = −1.21 V versus E0′(O2/H2O), demonstrating additive voltages across the individual junctions (n–p+-Si Eoc = −0.5 V versus solution; WO3/liquid Eoc = −0.73 V versus E0′(O2/H2O)). Optical concentration (12×, AM1.5D) shifted the open-circuit potential to Eoc = −1.27 V versus E0′(O2/H2O) and resulted in unassisted H2 production during two-electrode measurements (anode: tandem device, cathode: Pt disc). The solar energy-conversion efficiencies were very low, 0.0068% and 0.0019% when the cathode compartment was saturated with Ar or H2, respectively, due to the non-optimal photovoltage and band-gap of the WO3 that was used in the demonstration system to obtain stability of all of the system components under common operating conditions while also insuring product separation for safety purposes.