gebhart/patrepeval huggingface dataset:
Frequency difference limens for short-duration tones (1973)

Models which attempt to account for our ability to discriminate the pitch of pure tones are discussed. It is concluded that models based on a place (spectral) analysis should be subject to a limitation of the type Δf⋅d ⩾ constant, where Δf is the frequency difference limen (DL) for a tone pulse of duration d. The value of this constant will depend on the ability of the system to resolve small intensity differences. If a resolution of 1 dB is assumed, the value of the constant is about 0.24. In principle, a mechanism based on the measurement of time intervals could do considerably better than this. Frequency DLs were measured over a wide range of frequencies and durations. It was found that at short durations the product of Δf and d was about one order of magnitude smaller than the minimum predicted from the place model, except for frequencies above 5 kHz. A “kink” in the obtained functions was also observed at about 5 kHz. It is concluded that the evidence is consistent with the operation of a time-measuring mechanism for frequencies below 5 kHz, and with a spectral or place mechanism for frequencies above this.
The genus <i>Cordyceps</i>: a chemical and pharmacological review (2012)

More research is required to discover the full extent of the activity of Cordyceps.
Electrocardiographic Diagnosis of Acute Myocardial Infarction During Ventricular Pacing (1998)

Figure 1. Baseline ECG showing ventricular pacing at 69 pulses per minute, with typical repolarization abnormalities and underlying atrial fibrillation.
A simple method suitable to study de novo root organogenesis (2014)

De novo root organogenesis is the process in which adventitious roots regenerate from detached or wounded plant tissues or organs. In tissue culture, appropriate types and concentrations of plant hormones in the medium are critical for inducing adventitious roots. However, in natural conditions, regeneration from detached organs is likely to rely on endogenous hormones. To investigate the actions of endogenous hormones and the molecular mechanisms guiding de novo root organogenesis, we developed a simple method to imitate natural conditions for adventitious root formation by culturing Arabidopsis thaliana leaf explants on B5 medium without additive hormones. Here we show that the ability of the leaf explants to regenerate roots depends on the age of the leaf and on certain nutrients in the medium. Based on these observations, we provide examples of how this method can be used in different situations, and how it can be optimized. This simple method could be used to investigate the effects of various physiological and molecular changes on the regeneration of adventitious roots. It is also useful for tracing cell lineage during the regeneration process by differential interference contrast observation of β-glucuronidase staining, and by live imaging of proteins labeled with fluorescent tags.
Design of a 32 bit microprocessor, TX1 (1989)

Implementation of the TX1 VLSI microprocessor is described. Particular emphasis is placed on the design method, which meets the requirements of short design time with reasonable chip size. A one-phase clock system, which is a better solution for high-speed operation but requires careful design for evading the skew problem, is discussed. Design for testability is embedded in the chip. The TX1 is fabricated with a 1.0 mu m two-layer metal CMOS process. The chip contains 450 K transistors in a 10.89*10.27 mm/sup 2/ die.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
The structure of object transportation and orientation in human-computer interaction (1998)

Article Free Access Share on The structure of object transportation and orientation in human-computer interaction Authors: Yanqing Wang School of Kinesiology, Simon Fraser University, Burnaby, BC, V5A 1S6, Canada School of Kinesiology, Simon Fraser University, Burnaby, BC, V5A 1S6, CanadaView Profile , Christine L. MacKenzie School of Kinesiology, Simon Fraser University, Burnaby, BC, V5A 1S6, Canada School of Kinesiology, Simon Fraser University, Burnaby, BC, V5A 1S6, CanadaView Profile , Valerie A. Summers Department of Computer Science, University of British Columbia, Vancouver, BC V6T 1Z4, Canada Department of Computer Science, University of British Columbia, Vancouver, BC V6T 1Z4, CanadaView Profile , Kellogg S. Booth Department of Computer Science, University of British Columbia, Vancouver, BC V6T 1Z4, Canada Department of Computer Science, University of British Columbia, Vancouver, BC V6T 1Z4, CanadaView Profile Authors Info & Claims CHI '98: Proceedings of the SIGCHI Conference on Human Factors in Computing SystemsJanuary 1998 Pages 312–319https://doi.org/10.1145/274644.274688Published:01 January 1998Publication History 51citation691DownloadsMetricsTotal Citations51Total Downloads691Last 12 Months56Last 6 weeks4 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Characterization of 17 Human Immunodeficiency Virus-1 Carrier Cell Lines with T cell, Myelomonocyte, or Megakaryocyte Lineages (1993)

Of 29 hematopoietic cell lines tested for susceptibility to human immunodeficiency virus (HIV)-1HTLV-IIIB infection, all CD4+ cell lines became infected. Continuous culturing of infected cell lines resulted in nine HIV-1 carrier cell lines, including, for the first time, an HIV-1 carrier megakaryoblastic cell line, MEG-01/HIV. The immunophenotypic profiles of a total of 17 HIV-1 carrier cell lines (nine newly and eight previously established cell lines) were compared with their respective parental noninfected cell lines. Except for total absence of CD4 expression, the expression of other antigens was variable among the 17 HIV-1 carrier cell lines. Persistent and consistent replication of infectious HIV-1 was detected in all of them in varying quantities. The great variability observed in both the altered marker expression, with respect to that of the noninfected parental cell lines, and in the quantities of persistently produced infectious HIV-1 was, nevertheless, specific to the individual cell lines. Furthermore, the present study demonstrates that there is no apparent correlation in the quantity of HIV-1 produced to either T cell, myelomonocytic cell, or megakaryocytic cell types. Instead, the results suggest that a particular interaction between HIV-1 and individual clonal cell lines may provide insight into the extremely complex immune dysregulation associated with the pathogenesis of acquired immune deficiency syndrome. Thus, the 17 HIV-1 carrier cell lines of diverse origin presented here provide valuable and unique models for further understanding acquired immune deficiency syndrome pathogenesis at the cellular and molecular levels.
Affinity of trazodone for human penile α <sub>1</sub> ‐ andα <sub>2</sub> ‐adrenoceptors (2000)

Trazodone has high and moderate affinity for human alpha1- and alpha2-adrenoceptors, respectively; this might contribute to its reported beneficial effects in erectile dysfunction.
A Deep Neural Network-Driven Feature Learning Method for Multi-view Facial Expression Recognition (2016)

In this paper, a novel deep neural network (DNN)-driven feature learning method is proposed and applied to multi-view facial expression recognition (FER). In this method, scale invariant feature transform (SIFT) features corresponding to a set of landmark points are first extracted from each facial image. Then, a feature matrix consisting of the extracted SIFT feature vectors is used as input data and sent to a well-designed DNN model for learning optimal discriminative features for expression classification. The proposed DNN model employs several layers to characterize the corresponding relationship between the SIFT feature vectors and their corresponding high-level semantic information. By training the DNN model, we are able to learn a set of optimal features that are well suitable for classifying the facial expressions across different facial views. To evaluate the effectiveness of the proposed method, two nonfrontal facial expression databases, namely BU-3DFE and Multi-PIE, are respectively used to testify our method and the experimental results show that our algorithm outperforms the state-of-the-art methods.
Growth of α-Al2O3 films by molecular layer epitaxy (1987)

Single-crystal α-Al2O3 films are, for the first time, successfully grown on sapphire wafers above ∼600 °C by the molecular layer epitaxy (MLE) method using AlCl3 vapor and a He 15%O2 gas mixture. The average growth rate observed barely depends on the substrate temperature, being ∼0.09 nm per cycle of gas transport, under the used growth conditions. The epitaxial growth of α-Al2O3 films on single-crystal Nb films at ∼500 °C by the MLE method is also confirmed for the first time.
A partitioned wavelet-based approach for image compression using FPGA's (2002)

Discrete wavelet transformations (DWT) followed by embedded zerotree encoding (EZT) is a very efficient technique for image compression. However, the algorithms proposed in the literature assume random access to the whole image. This makes the algorithms unsuitable for hardware solutions because of extensive access to external memory. Here, we introduce efficient FPGA hardware approaches for DWT for lossless and lossy image compression targeting the minimization of external memory accesses. In particular, the approaches allow both parallel wavelet transformation and parallel embedded zero tree encoding.
Battery-utility interface using soft switched ac link supporting low voltage ride through (2009)

In this paper, a novel soft switched high frequency AC link converter is proposed for use as a battery utility interface. The proposed configuration uses 10 bidirectional switches interfacing with an AC link consisting of an inductor and a parallel capacitance. The capacitance produces soft turn off in all operating conditions, and turn on always occurs with zero voltage. This converter has several significant advantages such as: high efficiency, light weight, low cost, very short power reversal time and the low voltage ride through (LVRT) capability. These characteristics make this converter an outstanding option for the battery-utility interface. Utility scale battery systems are being developed to improve grid stability, provide peaking power, and to improve the penetration of renewable energy sources. In order to provide the required grid stabilization, power converters which can switch in a few milliseconds from charging batteries to supplying power to the electric grid are required, and this must be done at low cost with high powered converters. The AC link converter proposed is capable of such rapid switching speeds, due to its high frequency of internal operation. Power reversal speed is only limited by the resonance period of the input/output filters, which have low per unit reactance due to the current sourced nature of the converter and its high frequency of internal operation, which is made possible by the fully soft switched converter. Power reversal times of less than 0.5 ms are demonstrated through simulation. Another important factor in the grid stability is low voltage ride through capability. In this paper, it will be shown that our proposed converter has this capability. Both simulations and experimental results will be included in this paper.
Short Children Born Small for Gestational Age (SGA) (2006)

Wij hebben verschillende onderzoeken gedaan naar kinderen met een laag geboorte lengte of gewicht voor de zwangerschapsduur (SGA=Small for Gestational Age) en een kleine lengte waarvoor behandeling met groeihormoon (GH). Aan mijn promtieonderzoek hebben de kinderen van de 1e en 2e Nederlandse GH- trial deel genomen. Deze studies zijn gestart tussen 1991-2001. Beide studies gebruiken dezelfde inclusie en exclusie criteria. Kort samengevat gaat het om kinderen die een geboortelengte of geboorte gewicht hadden kleiner dan -2.0 SDS en op moment van inclusie een lengte kleiner dan -2 SDS en een leeftijd tussen de 3.0 en 7.9 jaar. Het zijn gezonde kinderen zonder syndromen of andere chronische afwijkingen die hun lengte zouden kunnen hebben beÃ¯nvloed. In de 1e studie werden de kinderen met een enkelvoudige of dubbele dosis GH behandeld. In de 2e studie werd 2/3 van de kinderen behandeld met GH en 1/3 bleef 3 jaar onbehandeld en startte daarna met GH. Eerdere resu! \nltaten van deze studies zijn beschreven in de proefschriften van W. de Waal, T. Sas and N. Arends. \nIn eerste instantie hebben we gekeken naar het effect van SGA op de orgaan ontwikkeling. We hebben onderzoek gedaan naar de adrenarche in SGA kinderen met een kleine lengte in vergelijking met AGA kinderen. Tevens is er gekeken in de SGA groep wat de incidentie van premature pubarche is. We hebben onderzocht wat het effect is van foetale groei op het aantal ovariÃ«le follikels bij SGA meisjes in vergelijking met AGA meisjes. Onderzocht is wat het effect is van foetale groei op de testes ontwikkeling bij SGA jongens in vergelijking met AGA jongens. Tevens hebben we onderzocht wat het effect is van GH op de adrenarche, ovaria en testis functie. We hebben de puberteitontwikkeling onderzocht van GH behandelde SGA kinderen door middel van het bepalen van de leeftijd en lengte waarop de puberteit start, de progressie van de puberteit en de lengte winst tijdens de puberteit. Er is onderzocht of SGA kinderen een verminderde voedingsintake hebben in vergelijking met gezonde Nederlan! \ndse kinderen. Tevens hebben we de voedingsintake in combinatie met body compositie en serum IGF-I, IGFBP3 en leptine van GH behandelde kinderen vergeleken met onbehandelde SGA kinderen. Tenslotte hebben we onderzocht wat het effect is van GH op de kwaliteit van leven in vergelijking met onbehandelde SGA kinderen.
A highly polymorphic VNTR locus on the long arm of chromosome 4 (1991)

The probe, EFD 139.1, was isolated as described by Nakamura et al. (1). It is cloned into the plasmid vector pUC18. The locus designation is D4S184. Polymorphism: The probe EFD 139.1 detects a multi-allele polymorphism in HindH digests of human DNA. At least 11 different alleles have been observed. The allelic fragments vary in size from 3.5 to 8.0 kbp. Three invariant fragments are observed at 0.5, 0.7 and 2.0 kbp. Chromosomal Localization: The allelic fragments were assigned to the q21-qter region of chromosome 4 using somatic cell hybrids (2). The three constant bands are derived from the acrocentric chromosomes (13, 14, 15, 21 and 22) as determined from a hybrid cell mapping panel. Mendelian Inheritance: The codominant inheritance of alleles was demonstrated in 30 meioses (see Fig.).
Current Use of Limited-Entry Hydraulic Fracturing in the Codell/Niobrara Formations—DJ Basin (1995)

Abstract In the last several years, limited-entry perforating has been used for hydraulically fracturing the Codell and Niobrara formations in the Denver-Julesburg (DJ) Basin. Limited-entry perforating reduces stimulation costs with no apparent effect on production. Several papers have presented guidelines for designing a limited-entry treatment. A primary concern for treating multiple intervals is to ensure that both zones receive the necessary treatment. Currently, some operators simply ratio the number of perforations in each interval to the volume of treatment required for each interval. To ensure that both zones are being treated, a minimum pressure drop of 700 to 1,000 psi is usually used for limited-entry design. Changes in the perforation discharge coefficient and diameter during the treatment, combined with changes in the net treating pressure, affect the perforation pressure drop calculation. To determine the actual pressure drop across the perforations, designers use a real-time spreadsheet calculation. This paper reviews limited-entry treatments pumped in 34 wells that verify spreadsheet calculations. Changes in the perforation discharge coefficient and diameter will be presented, as well as the effect of proppant concentration and velocity through the perforation. The current spreadsheet calculation used on location to calculate the pressure drop across the perforations is also discussed.
Fetal Human Cytomegalovirus Transmission Correlates with Delayed Maternal Antibodies to gH/gL/pUL128-130-131 Complex during Primary Infection (2013)

Primary human cytomegalovirus (HCMV) infections during pregnancy are associated with a high risk of virus transmission to the fetus. To identify correlates of intrauterine HCMV transmission, serial serum samples from HCMV transmitter and non-transmitter pregnant women with primary HCMV infection were analyzed for the presence of neutralizing antibodies against different glycoproteins and glycoprotein complexes, which are known to mediate entry into distinct types of host cells. Neutralizing activity was detected in the sera early after primary infection; absorption with a soluble pentameric complex formed by gH/gL/pUL128-131, but not with gH/gL dimer or with gB, abolished the capacity of sera to neutralize infection of epithelial cells. Importantly, an early, high antibody response to pentamer antigenic sites was associated with a significantly reduced risk of HCMV transmission to the fetus. This association is consistent with the high in vitro inhibition of HCMV infection of epithelial/endothelial cells as well as cell-to-cell spreading and virus transfer to leukocytes by anti-pentamer antibodies. Taken together, these findings indicate that the HCMV pentamer complex is a major target of the antibody-mediated maternal immunity.
Education Around the World (2022)

Committee News| October 2022 Education Around the World Elizabeth T. Drum, MD, FAAP, FCPP, FASA Elizabeth T. Drum, MD, FAAP, FCPP, FASA Search for other works by this author on: This Site PubMed Google Scholar ASA Monitor October 2022, Vol. 86, 32–33. https://doi.org/10.1097/01.ASM.0000890096.16846.1d Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Search Site Citation Elizabeth T. Drum; Education Around the World. ASA Monitor 2022; 86:32–33 doi: https://doi.org/10.1097/01.ASM.0000890096.16846.1d Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll PublicationsASA Monitor Search Advanced Search Topics: botswana, internship and residency, kenya, medical residencies, uganda Education is an essential part of the Committee on Global Humanitarian Outreach (GHO). Although COVID-19 has changed many aspects of international travel and work, there is still an immense need for safe surgery and anesthesia worldwide (asamonitor.pub/3C2symk). Efforts by ASA members and other global anesthesia partners such as the World Federation of Societies of Anaesthesiologists (WFSA) should be an inspiration for all of us (ASA Monitor 2022;86:14-5; ASA Monitor 2022;86:40). In this report, we highlight activities of the GHO Resident International Anesthesia Scholarship recipients. In October 2021, Edward C. Clune, MD, was awarded the Nicholas M. Greene, MD, Award for Outstanding Humanitarian Contribution (ASA Monitor 2021;85:1-7). He is currently an adjunct faculty member at the University of Botswana as well as a faculty member at Beth Israel Deaconess Medical Center in Boston, Massachusetts. The GHO Committee sponsored two trainees to join Dr. Clune... You do not currently have access to this content.
Infrared laser radiation induced changes in the IR absorption spectra of thin polymer films (2000)

The presented work demonstrates that powerful laser radiation causes changes in absorbance spectra of epoxy resin and polyethylene. Thin polymer films were located between IR AgBrCl optical fibres and exposed to the radiation of a CO2 laser. The output of the laser source was varied in the range 0-8.5 W. Absorbance spectra were measured by a Fourier transform IR spectrophotometer. It was revealed that characteristic absorbance peaks of polymers decay under the powerful IR light. The apparent dependence of peak magnitude on IR radiation power has been established. The mathematical theory of the observed effect was worked out. The authors suggest that the effect under discussion is caused by the oxygen-free thermal action of IR radiation on the chemical structure of polymer materials. The revealed effect could be effectively used for the lowering of losses in adhesive contacts of IR optic elements. The novelty of the proposed method lies in the fact that thermal treatment is localized strictly in the adhesive contact: optical elements to be contacted (fibres, lenses etc), which are highly transparent in the IR, do not experience the IR radiation, but the polymer adhesive is subjected to a temperature rise. The phenomenon could be effectively used for the lowering of losses in optical contacts and recording and storage of information in polymer films as well.
Motor unit types, recruitment and plasticity in health and disease (1981)

info:eu-repo/semantics/published
HRM- A Literature Survey (2014)

There is an ongoing debate in research over the source of organisational competitive advantage.
Niclosamide, a Drug with Many (Re)purposes (2018)

Niclosamide is an anthelmintic drug that has been used for over 50 years mainly to treat tapeworm infections. However, with the increase in drug repurposing initiatives, niclosamide has emerged as a true hit in many screens against various diseases. Indeed, from being an anthelmintic drug, it has now shown potential in treating Parkinson's disease, diabetes, viral and microbial infections, as well as various cancers. Such diverse pharmacological activities are a result of niclosamide's ability to uncouple mitochondrial phosphorylation and modulate a selection of signaling pathways, such as Wnt/β-catenin, mTOR and JAK/STAT3, which are implicated in many diseases. In this highlight, we discuss the plethora of diseases that niclosamide has shown promise in treating.
DeepLoco: Fast 3D Localization Microscopy Using Neural Networks (2018)

Abstract Single-molecule localization super-resolution microscopy (SMLM) techniques like STORM and PALM have transformed cellular microscopy by substantially increasing spatial resolution. In this paper we introduce a new algorithm for a critical part of the SMLM process: estimating the number and locations of the fluorophores in a single frame. Our algorithm can analyze a 20000-frame experimental 3D SMLM dataset in about one second — substantially faster than real-time and existing algorithms. Our approach is straightforward but very different from existing algorithms: we train a neural network to minimize the Bayes’ risk under a generative model for single SMLM frames. The neural network maps a frame directly to a collection of fluorophore locations, which we compare to the ground truth using a novel loss function. While training the neural network takes several hours, it only has to be done once for a given experimental setup. After training, localizing fluorophores in new images is extremely fast — orders of magnitude faster than existing algorithms. Faster recovery opens the door to real-time calibration and accelerated acquisition, and future work could tackle more complicated optical systems and more realistic simulators.