gebhart/patrepeval huggingface dataset:
Recognizing the professionals who help to solve "the population problem". (1984)

It is the population professionals who belong to the "developing" world who have helped to create and expand the basic information which makes it possible to describe the demographic situation of countries and social groups more adequately. These professionals have developed, promoted, and applied analytical techniques which have enriched understanding of the components of demographic change. It is these professionals who have managed to make major contributions towards explaining the relationship between demographic and socioeconomic factors. The professionals are insisting on developing applied, theoretical, and methodological population research, the results of which will serve essentially to propose alternatives for action. This group of professionals participates daily in the training of technical staff and professionals and academics, specialists who will continue to promote the development of demography as a discipline. Finally, these professionals, through various publications, keep population topics at the center of the attention of those who are concerned with studying them. Groups of countries in Africa, Asia, and Latin America suffer, although to a different extent and in different ways, from the problems created by the rapid growth of certain cities, particularly capital cities. In addition to the problems which may arise from the operation of the specific population dynamics in different countries and between different social groups within those countries, there are those arising from the unequal distribution of agricultural land, foodstuffs, and wealth in general, those arising from the unjust organization of the international economy and from the obsolete international financial structure, and those deriving from the irrational use of resources for military spending and the manufacture and stockpiling of vast nuclear arsenals.
Design and Analysis of a Neuromemristive Reservoir Computing Architecture for Biosignal Processing (2016)

Reservoir computing (RC) is gaining traction in several signal processing domains, owing to its non-linear stateful computation, spatiotemporal encoding, and reduced training complexity over recurrent neural networks (RNNs). Previous studies have shown the effectiveness of software-based RCs for a wide spectrum of applications. A parallel body of work indicates that realizing RNN architectures using custom integrated circuits and reconfigurable hardware platforms yields significant improvements in power and latency. In this research, we propose a neuromemristive RC architecture, with doubly twisted toroidal structure, that is validated for biosignal processing applications. We exploit the device mismatch to implement the random weight distributions within the reservoir and propose mixed-signal subthreshold circuits for energy efficiency. A comprehensive analysis is performed to compare the efficiency of the neuromemristive RC architecture in both digital(reconfigurable) and subthreshold mixed-signal realizations. Both Electroencephalogram (EEG) and Electromyogram (EMG) biosignal benchmarks are used for validating the RC designs. The proposed RC architecture demonstrated an accuracy of 90 and 84% for epileptic seizure detection and EMG prosthetic finger control, respectively.
Brain Hyperthermia During Physiological and Pathological Conditions: Causes, Mechanisms, and Functional Implications (2004)

Although brain metabolism consumes high amounts of energy and is accompanied by intense heat production, brain temperature is usually considered a stable, tightly regulated homeostatic parameter. Current animal research, however, has shown that different forms of functional neural activation are accompanied by relatively large brain hyperthermia (2-3 degrees C), which has an intra-brain origin; cerebral circulation plays a crucial role in dissipating this potentially dangerous metabolic heat from brain tissue. Brain hyperthermia, therefore, reflects enhanced brain metabolism and is a normal physiological phenomenon that can be enhanced by interaction with common elements of an organism's environment. There are, however, instances when brain hyperthermia becomes pathological. Both exposure to extreme environmental heat and intense physical activity in a hot, humid environment restrict heat dissipation from the brain and may push brain temperatures to the limits of physiological functions, resulting in acute life-threatening complications and destructive effects on neural cells and functions of the brain as a whole. Brain hyperthermia may also result from metabolic activation induced by various addictive drugs, such as heroin, cocaine, and meth-amphetamine (METH). In contrast to heroin and cocaine, whose stimulatory effects on brain metabolism invert with increases in dose, METH increases brain metabolism dose-dependently and diminishes heat dissipation because of peripheral vasoconstriction. The thermogenic effects of this drug, moreover, are enhanced during physiological activation, resulting in pathological brain hyperthermia. Since brain hyperthermia exacerbates drug-induced toxicity and is destructive to neural cells, uncontrollable use of amphetamine-like drugs under conditions restricting heat dissipation from the brain may result both in acute life-threatening complications and clinically latent but dangerous morphological and functional brain destruction.
Continuous Measurement of Intraarterial pHa, Paco2, and Pao2, in the Operating Room (1991)

Miniaturized sensors based upon the principles of optical fluorescence can measure the pH, PCO2, and PO2 of liquid or gas media. A prototype of a three-component fiberoptic sensor has been developed for intraarterial application by CDI, 3M Health Care, Irvine, California. We report the first study of this continuous intraarterial monitor in patients undergoing surgical procedures under general anesthesia. Fourteen patients participated in the study. The fiberoptic sensor was calibrated before insertion and then passed through an existing 18-gauge radial artery cannula. Blood samples were drawn at frequent intervals through the same cannula for in vitro blood gas analysis. For each of the 87 arterial blood gas samples obtained, the in vitro values of pHa, PaCO2, and PaO2 were compared with simultaneous readings from the fiberoptic sensor. For pHa, the mean error (error = fiberoptic value minus in vitro value) or "bias" of the fiberoptic data was -0.032 and the standard deviation of error or "precision" was 0.042. For PaCO2, the bias was -3.8 mm Hg and the precision was 4.7 mm Hg. For PaO2, the bias was -9.0 mm Hg and the precision was 23.3 mm Hg. For PaO2 values less than 175 mm Hg, the bias was -8.5 mm Hg and the precision was 8.3 mm Hg. Expressed in terms of percentage errors, the bias +/- precision values were -11.5% +/- 13.3% for PaCO2, and -6.2% +/- 10.0% for PaO2. The duration of the surgical procedures ranged from 1.6 to 8 h with an average of 4.2 h.(ABSTRACT TRUNCATED AT 250 WORDS)
Differentiate Depression From Dementia (2003)

Depression and dementia are two common problems among the elderly that may be difficult to differentiate. Prompt and accurate diagnosis is important not only for symptom management, but to reduce social isolation and cognitive impairment, and prevent physical disability and suicide. Use this six-step process as a guideline to help differentiate depression and dementia.
The Internet of Flying-Things: Opportunities and Challenges with Airborne Fog Computing and Mobile Cloud in the Clouds (2015)

This paper focuses on services and applications provided to mobile users using airborne computing infrastructure. We present concepts such as drones-as-a-service and fly-in,fly-out infrastructure, and note data management and system design issues that arise in these scenarios. Issues of Big Data arising from such applications, optimising the configuration of airborne and ground infrastructure to provide the best QoS and QoE, situation-awareness, scalability, reliability, scheduling for efficiency, interaction with users and drones using physical annotations are outlined.
Solid phase epitaxial seed for laser-crystallized silicon on glass substrates (1991)

A new method for obtaining thin silicon film on glass substrates (SOG) has been introduced. This technique uses solid phase epitaxy (SPE) and laser crystallization to fabricate an orientation-controlled SOG structure. Heat treatment of amorphous SOG substrate in contact with mesa striped (100)-oriented Si seed crystal was performed at 543 °C for 16 h to form the SPE layer. The most important feature of the present external seeding technique is the separation of the seed from the substrate after SPE. Successful demonstration of seeded laser crystallization shows the usefulness of the external seed SPE.
Decision making under uncertainty (1996)

article Free Access Share on Decision making under uncertainty Author: Judea Pearl University of California at Los Angeles University of California at Los AngelesView Profile Authors Info & Claims ACM Computing SurveysVolume 28Issue 1March 1996 pp 89–92https://doi.org/10.1145/234313.234354Published:01 March 1996Publication History 17citation2,723DownloadsMetricsTotal Citations17Total Downloads2,723Last 12 Months88Last 6 weeks28 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my Alerts New Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Automatic Problem Localization via Multi-dimensional Metric Profiling (2013)

Debugging today's large-scale distributed applications is complex. Traditional debugging techniques such as breakpoint-based debugging and performance profiling require a substantial amount of domain knowledge and do not automate the process of locating bugs and performance anomalies. We present Orion, a framework to automate the problem-localization process in distributed applications. From a large set of metrics, Orion intelligently chooses important metrics and models the application's runtime behavior through pair wise correlations of those metrics in the system, within multiple non-overlapping time windows. When correlations deviate from those of a learned correct model due to a bug, our analysis pinpoints the metrics and code regions (class and method within it) that are most likely associated with the failure. We demonstrate our framework with several real-world failure cases in distributed applications such as: HBase, Hadoop DFS, a campus-wide Java application, and a regression testing framework from IBM. Our results show that Orion is able to pinpoint the metrics and code regions that developers need to concentrate on to fix the failures.
Hsf1 in Her2-positive Breast Cancer (2011)

Abstract : This study demonstrates that Hsf1 controls development of Her2-positive cancer both at the stage of initiation, via control of the oncogene-induced senescence, and progression, via regulation of tumor angiogenesis. It also dissects the mechanism of effects of Hsf1 on tumor angiogenesis, and demonstrates that Hsf1 regulates expression of the major angiogenesis factor HIF- 1, and this regulation involves the translation regulator HuR. This program provides rationale for development of Hsf1 inhibitors that can inhibit multiple pathways in tumor initiation and progression. It also establishes a simple xenograft model that can be used for anti-Hsf1 drug testing.
Diels–Alder adducts of <i>ortho</i>-benzoquinones: rearrangements and further transformations (1997)

ortho-Benzoquinones substituted with an electron-withdrawing group (EWG = CO 2 Me, COSMe, COCH 3 , CHO) at C-3 or C-4 react as dienophiles at the C3—C4 double bond in Diels–Alder reactions with several dienes, with predictable regiochemistry. The adducts undergo migration of the "angular" EWG substituent with concomitant aromatization to produce substituted catechols. The bicyclic products can be oxidized in situ and annelated by a further Diels–Alder reaction to yield 9,10-phenanthraquinone systems. When (2E)-2,4-pentadienol is employed as the diene in the second cycloaddition, reaction of the alcoholic hydroxyl group with one of the quinone carbonyl groups results in the production of tetracyclic lactols 22a, 22b, and 23. Keywords: benzoquinone, Diels–Alder, rearrangement, phenanthraquinone, phenanthrofuran.
Perceptual and physiological responses to the visual complexity of fractal patterns. (2005)

Fractals have experienced considerable success in quantifying the complex structure exhibited by many natural patterns and have captured the imagination of scientists and artists alike. With ever widening appeal, they have been referred to both as "fingerprints of nature" and "the new aesthetics." Our research has shown that the drip patterns of the American abstract painter Jackson Pollock are fractal. In this paper, we consider the implications of this discovery. We first present an overview of our research from the past five years to establish a context for our current investigations of human response to fractals. We discuss results showing that fractal images generated by mathematical, natural and human processes possess a shared aesthetic quality based on visual complexity. In particular, participants in visual perception tests display a preference for fractals with mid-range fractal dimensions. We also present recent preliminary work based on skin conductance measurements that indicate that these mid-range fractals also affect the observer's physiological condition and discuss future directions based on these results.
Effect of prostaglandin E<sub>1</sub>on TNF-induced vascular inflammation in human umbilical vein endothelial cells (2010)

Prostaglandin E1 (PGE1) is a member of the prostaglandins and has a variety of cardiovascular protective effects. Increasing attention has been paid to the anti-inflammation activity of PGE1, but little direct evidence has been found. We investigated the effects of PGE1 on cell adhesion and inflammation and the mechanisms responsible for this activity in tumor necrosis factor (TNF)-treated human umbilical vein endothelial cells. Results demonstrated that pretreatment with PGE1 decreased the adhesion between vascular endothelial cells and monocytes, reduced the expression of vascular cell adhesion molecule-1, intercellular adhesion molecule-1, and E-selectin in vascular endothelial cells. In addition, PGE1 suppressed TNF-induced NF-kappaB activation and production of reactive oxygen species. We concluded that PGE1 suppressed the vascular inflammatory process, which might be closely related to the inhibition of reactive oxygen species and NF-kappaB activation in human umbilical vein endothelial cells.
Lossy Electric Transmission Line Soft Fault Diagnosis: an Inverse Scattering Approach (2010)

Abstract—In this paper, the diagnosis of soft faults in lossy electric transmission lines is studied through the inverse scattering approach. The considered soft faults are modeled as continuous spatial variations of distributed characteristic parameters of transmission lines. The diagnosis of such faults from reflection and transmission coefficients measured at the ends of a line can be formulated as an inverse problem. The relationship between this inverse problem and the inverse scattering theory has been studied by Jaulent in 1982 through transformations from the telegrapher’s equations of transmission lines to Zakharov-Shabat equations. The present paper clarifies and completes the computation of the theoretic scattering data required by the inverse scattering transform from the practically measured engineering scattering data. The inverse scattering method is then applied to numerically simulated lossy transmission lines to confirm the feasibility of the studied approach to soft fault diagnosis. Index Terms—inverse scattering, lossy transmission line, soft fault diagnosis, telegrapher’s equations, Zakharov-Shabat equations. I.
Authentication of Digital Image using Exif Metadata and Decoding Properties (2018)

This work presents a robust analysis of digital images to detect the modifications/ morphing/ editing signs by using the image’s exif metadata, thumbnail, camera traces, image markers, Huffman codec and Markers, Compression signatures etc. properties. The details of the whole methodology and findings are described in the present work. The main advantage of the methodology is that the whole analysis has been done by using software/tools which are easily available in open sources.
Differential regulation of p21 by p53 and Rb in cellular response to oxidative stress (1999)

Oxidative stress to mammalian cells causes cellular damage and triggers inducible cellular responses leading to cell death by apoptosis. In this paper, we report that p53 was required for programmed cell death induced by oxidative stress in both mouse and human cells and that p53 transactivation was involved in induction of oxidative cell death. Furthermore, we show that p21 was highly responsive to oxidative stress in a p53-dependent manner and that ectopic expression of p21 could increase cellular susceptibility to oxidative stress in the absence of p53. However, p21 was not required for p53-directed oxidative cell death because mouse embryo fibroblasts MEFs lacking p21(p21-/- MEFs) were still susceptible to oxidative cell death. Interestingly, bax, a cell-death mediator regulated by p53, was overexpressed in p21-/- MEFs that underwent cell death by oxidative stress, suggesting a compensation for loss of p21 that may be responsible for the existence of cell-death responses in p21-knockout mouse fibroblasts. Finally, we provide evidence that the retinoblastoma gene product (Rb) is a negative regulator of p21 and a repressor of the cellular apoptotic process. Because p21 is regulated by p53 positively and by Rb negatively, p21 may be a link between p53 and Rb in determining cell fate after oxidative damage.
A high-performance entropy decoding system for H.264/AVC (2009)

We present a high-performance entropy decoding system for H.264/AVC. This system includes a variable length coding (VLC) decoder, a context-based adaptive binary arithmetic coding (CABAC) decoder, and a run-level converter. Each syntax element above slice data is decoded by VLC decoder within a clock cycle. The CABAC decoder decodes the syntax elements at slice data and below through pipeline mechanism. A run-level converting method is designed and integrated into the system to improve the output efficiency of decoded quantized coefficients. This system can process 574,712 macroblock/s operating at 300 MHz, quite enough for real-time decoding for H.264/AVC HD level 4.1 video sequences.
Mechanical Property Investigation of Soft Materials by Cantilever‐Based Optical Interfacial Force Microscopy (2012)

Cantilever-based optical interfacial force microscopy (COIFM) was applied to the investigation of the mechanical properties of soft materials to avoid the double-spring effect and snap-to-contact problem associated with atomic force microscopy (AFM). When a force was measured as a function of distance between an oxidized silicon probe and the surface of a soft hydrocarbon film, it increases nonlinearly in the lower force region below ∼10 nN, following the Herzian model with the elastic modulus of ∼50 MPa. Above ∼10 nN, it increases linearly with a small oscillatory sawtooth pattern with amplitude 1-2 nN. The pattern suggests the possible existence of the layered structure within the film. When its internal part of the film was exposed to the probe, the force depends on the distance linearly with an adhesive force of -20 nN. This linear dependence suggests that the adhesive internal material behaved like a linear spring with a spring constant of ∼1 N/m. Constant-force images taken in the repulsive and attractive contact regimes revealed additional features that were not observed in the images taken in the noncontact regime. At some locations, however, contrast inversions were observed between the two contact regimes while the average roughness remained constant. The result suggests that some embedded materials had spring constants different from those of the surrounding material. This study demonstrated that the COIFM is capable of imaging mechanical properties of local structures such as small impurities and domains at the nanometer scale, which is a formidable challenge with conventional AFM methods.
Anhydrobiosis in nematodes: Inhibition of the browning reaction of reducing sugars with dry proteins (1979)

Abstract Decay of primary amines associated with proteins of anhydrobiotic and lyophilized, fresh nematodes (Aphelenchus avenae) occurs more readily in the lyophilized, fresh worms than in the anhydrobiotic ones. Addition of glucose accelerates the rate of decay, while addition of trehalose along with the glucose inhibits the effect of the glucose. Similar results were obtained with bovine serum albumin stored in the presence of glucose, glucose and rehalose, or trehalose. The data are interpreted to mean that not only does trehalose not participate in a browning reaction with dry proteins, but that it also inhibits browning reactions between dry proteins and reducing sugars.
Isolation of two soybean G‐box binding factors which interact with a G‐box sequence of an auxin‐responsive gene (1995)

G-box binding factors (GBFs) constitute a family of plant DNA-binding proteins that bind to the G-box motif, a regulatory cis element present in many plant genes with a palindromic DNA motif of CACGTG. Previously TCCACGTGTC, a G-box motif, from an auxin responsive gene GmAux28 has been identified as a sequence-specific protein-binding site. Here the isolation of two soybean cDNA clones, referred to as SGBF-1 and SGBF-2, encoding proteins which bind to the G-box motif is reported. The primary structure of SGBF-1 and SGBF-2 predicts that these proteins contain a basic leucine zipper (bZIP) DNA-binding domain and an N-terminal proline-rich domain. A dramatic difference in the pattern of protein-DNA complex formation was observed when recombinant SGBF-1 and SGBF-2 proteins were analyzed by electrophoretic mobility shift assays (EMSAs). The SGBF-1 binding pattern obtained with the G-box probe resulted in three major retarded bands while the SGBF-2 formed a single complex. This shows that the characteristically diffuse banding pattern of plant nuclear proteins interacting with the G-box is also observed in a binding assay using only one recombinant GBF. EMSAs were performed with a few selected binding sequences to study the effect of flanking nucleotides to the hexanucleotide G-box core motif. The binding specificity of the SGBF proteins resembles that described for type A cauliflower nuclear G-box binding proteins which bind class I G-box elements [(G/T)(C/A)CACGTG(G/T)(A/C)]. Phylogenetic analysis of 13 GBF-like proteins from various plant species reveals that the SGBF-1 and SGBF-2 proteins belong to different lineages, suggesting that they may have distinct functions in activating transcription.
Social interactions: A first-person perspective (2012)

This paper presents a method for the detection and recognition of social interactions in a day-long first-person video of u social event, like a trip to an amusement park. The location and orientation of faces are estimated and used to compute the line of sight for each face. The context provided by all the faces in a frame is used to convert the lines of sight into locations in space to which individuals attend. Further, individuals are assigned roles based on their patterns of attention. The rotes and locations of individuals are analyzed over time to detect and recognize the types of social interactions. In addition to patterns of face locations and attention, the head movements of the first-person can provide additional useful cues as to their attentional focus. We demonstrate encouraging results on detection and recognition of social interactions in first-person videos captured from multiple days of experience in amusement parks.