gebhart/patrepeval huggingface dataset:
Dial and see (2005)

IVR (interactive voice response) menu navigation has long been recognized as a frustrating interaction experience. We propose an IM-based system that sends a coordinated visual IVR menu to the caller's computer screen. The visual menu is updated in real time in response to the caller's actions. With this automatically opened supplementary channel, callers can take advantages of different modalities over different devices and interact with the IVR system with the ease of graphical menu selection. Our approach of utilizing existing network infrastructure to pinpoint the caller's virtual location and coordinating multiple devices and multiple channels based on users' ID registration can also be more generally applied to create integrated user experiences across a group of devices.
On-Board SAR Processing - Spotlight SAR Processing (1999)

An algorithm for on-board processing of SAR raw data in the spotlight mode has been developed. The algorithm requires no interpolations and is phase preserving. The range cell migration correction is performed by the frequency scaling approach.
PneumoniaCheck: A Device for Sampling Lower Airway Aerosols (2010)

The pathogens causing pneumonia are difficult to identify because a high quality specimen from the lower lung is difficult to obtain. A new specimen collection device is designed to collect aerosol specimens selectively from the lower lung generated during deep coughing. The PneumoniaCheck device utilizes a separation reservoir and Venturi valve to segregate contents from the upper and lower airways. The device also includes several specially designed features to exclude oral contaminants from the sample and a filter to collect the aerosolized pathogens. Verification testing of PneumoniaCheck demonstrates effective separation of upper airway gas from the lower airway gas (p<0.0001) and exclusion of both liquid and viscous oral material (p<0.0001) from the collection chamber. The filters can collect 99.9997% of virus and bacteria sized particles from the sampled lower lung aerosols. The selective collection of specimens from the lower airway may aid in the diagnosis of specific pathogens causing pneumonia.
Pressure sensitive controller for electronic musical instruments (1981)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation David Friend, Royce C. Kahler; Pressure sensitive controller for electronic musical instruments. J. Acoust. Soc. Am. 1 July 1981; 70 (1): 272. https://doi.org/10.1121/1.386595 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAcoustical Society of AmericaThe Journal of the Acoustical Society of America Search Advanced Search |Citation Search
Multiple Roles for TnpI Recombinase in Regulation of Tn <i>5401</i> Transposition in <i>Bacillus thuringiensis</i> (1999)

Tn5401 is a class II transposable element derived from the gram-positive bacterium Bacillus thuringiensis. The 4,837-bp transposon encodes a Tn3-like transposase (TnpA) and an integrase-like recombinase (TnpI) and is notable for its unusually long 53-bp terminal inverted repeats (TIRs). The tnpA and tnpI genes are transcribed from a common promoter, designated P(R), that is subject to negative regulation by TnpI. The TIRs of Tn5401 each contain a 38-bp sequence that can be aligned with the 38- to 40-bp TIR sequences of Tn3-like transposons and an adjacent 12-bp sequence that binds TnpI. This unique juxtaposition of TnpA and TnpI binding sites suggests that TnpI may regulate the binding or catalytic activity of TnpA. The results of the present study indicate that TnpI, in addition to functioning as a site-specific recombinase and as a transcriptional repressor, is required for TnpA binding to the TIRs of Tn5401.
<i>Helicobacter pylori</i> Virulence and Genetic Geography (1999)

Isolated for the first time in 1982 from human gastric biopsy, Helicobacter pylori is responsible for gastritis, peptic ulcer, and gastric cancer. A pathogenicity island acquired by horizontal transfer, coding for a type IV secretion system, is a major determinant of virulence. The infection is now treated with antibiotics, and vaccines are in preparation. The geographic distribution suggests coevolution of man and Helicobacter pylori.
SAMPLES (2015)

We present SAMPLES: Self Adaptive Mining of Persistent LExical Snippets; a systematic framework for classifying network traffic generated by mobile applications. SAMPLES constructs conjunctive rules, in an automated fashion, through a supervised methodology over a set of labeled flows (the training set).
The Impact of Input-Mismatch on Flying-Adder Direct Period Synthesizer Output Jitter (2012)

Flying-Adder direct period synthesis is an emerging frequency synthesis technique. It is a mixed-signal technology that directly constructs the output clock period based on a multi-inputs reference. Owing to its open loop style and the usage of Time-Average-Frequency, this technique bears two important features: fine frequency resolution and instantaneous response. Although it has been used in commercial products for over a decade, the important issue associated with design/layout mismatch among its multi-inputs has not been studied in depth. In this paper, through a 55 nm Flying-Adder implementation, the cause of the mismatch is investigated. A mismatch model is created. Based on the model, the mismatch's impact is studied both in time and frequency domain. The experimental data from the chip is used to verify the observations from the analysis. Some useful insights are summarized in the end which will be useful in guiding future designs for commercial products. This study could also be helpful in developing a general theory for this problem.
Acid-degradable hyperbranched polymer and its application in bottom anti-reflective coatings (2008)

A photosensitive developer-soluble bottom anti-reflective coating (DBARC) system is described for KrF and ArF lithographic applications. The system contains an acid-degradable branched polymer that is self-crosslinked into a polymeric film after spin coating and baking at high temperature, rendering a solvent-insoluble coating. The DBARC coating is tunable in terms having the appropriate light absorption (k value) and thickness for desirable reflection control. After the exposure of the resist, the DBARC layer decrosslinks into developer-soluble small molecules in the presence of photoacid generator (PAG). Thus the DBARC layer is removed simultaneously with the photoresist in the development process, instead of being etched away in a plasma-etching chamber in the case of traditional BARC layers. The etch budget is significantly improved so that a thin resist can be used for better resolution. Alternatively, the etch step can be omitted in the case of the formation of layers that may be damaged by exposure to plasma.
Lubrication free centrifugal compressor. Technical report (1994)

This paper describes an effort to demonstrate the benefits of an innovative, lightweight, lubrication free centrifugal compressor that allows the use of environmentally sale alternate refrigerants with improved system efficiencies over current state-of-the-art technology. This effort couples the recently developed 3-D high efficiency centrifugal compressor and fabrication technologies with magnetic bearing technology and will then prove the performance, life and reliability of the compressor.
The Effect of Variable Binder Content and Sintering Temperature on the Mechanical Properties of WC–Co–VC/Cr<sub>3</sub>C<sub>2</sub>Nanocomposites (2014)

WC powders with an average crystallite size of 10 nm were successfully prepared by ball milling of micron-sized tungsten carbide powders. Grain growth inhibitors (VC and Cr3C2) with concentrations of 0.6 wt% each were added to nanocomposites of WC–9Co and WC–12Co, in both as-received and milled WC. Powder mixtures were then consolidated using spark plasma sintering technique at 1200 and 1300 °C for 10 min under high vacuum and pressure of 50 MPa. The influence of WC crystallite size, Co content, and sintering temperature over microstructure and mechanical properties of the resulting composites were studied through XRD and FESEM. Densification and attained grain sizes of the sintered products were measured by Archimedes principle and Scherrer procedure, respectively. Moreover, microhardness (Hv30) and fracture toughness were measured and compared for each composition to comparatively assess the individual effect. It was observed that the addition of VC and Cr3C2 resulted in decreased densification of the synthesized composites. These grain growth inhibitors were found to limit grain sizes to 131 nm with an average hardness of 1592 Hv30 and fracture toughness of 9.23 Mpam1/2.
Provider link state bridging (2008)

Wide area communications technology has been challenged to virtualize large numbers of Ethernet LAN segments. This is a consequence of a mismatch between the broadcast nature of the LAN segment and the extremely constrained connectivity implied by the p2p connections or tunnels available in the WAN environment, which have been combined to create virtual LAN segments. PBB-TE has been a practical demonstration of how filtering applied to a broadcast media can result in a connection. This article introduces provider link state bridging (PLSB), which adds a control plane to the PBB data plane in order to extend the techniques for manipulation of Ethernet bridges for unicast paths pioneered by PBB-TE. PLSB solves the problem of largescale virtualization of LAN segments over an Ethernet infrastructure by applying advances in computation performance to the multicast capabilities inherent in the Ethernet data plane. The result is that the fundamental primitives of connectivity today, the broadcast LAN segment and the connection, can be virtualized in a scalable manner on a common (but substantially larger and better utilized) Ethernet-based infrastructure.
Frequency-Discriminating Acoustic-Event Counter (1985)

Broadband events rejected. Acoustic-event counter discriminates against signals that simultaneously exceed preset amplitude thresholds in both low and high-frequency bands of its spectrum. Counter acts as spectral analyzer for mechanical vibrations. In combination with broadband acoustic transducer discriminates between signals and noise in acoustical destructive or nondestructive testing, vibration monitoring for machinery, burglar alarms, and other monitoring/warning systems.
Gene Therapy and Targeted Toxins for Glioma (2005)

The most common primary brain tumor in adults is glioblastoma. These tumors are highly invasive and aggressive with a mean survival time of 15-18 months from diagnosis to death. Current treatment modalities are unable to significantly prolong survival in patients diagnosed with glioblastoma. As such, glioma is an attractive target for developing novel therapeutic approaches utilizing gene therapy. This review will examine the available preclinical models for glioma including xenographs, syngeneic and genetic models. Several promising therapeutic targets are currently being pursued in pre-clinical investigations. These targets will be reviewed by mechanism of action, i.e., conditional cytotoxic, targeted toxins, oncolytic viruses, tumor suppressors/oncogenes, and immune stimulatory approaches. Preclinical gene therapy paradigms aim to determine which strategies will provide rapid tumor regression and long-term protection from recurrence. While a wide range of potential targets are being investigated preclinically, only the most efficacious are further transitioned into clinical trial paradigms. Clinical trials reported to date are summarized including results from conditionally cytotoxic, targeted toxins, oncolytic viruses and oncogene targeting approaches. Clinical trial results have not been as robust as preclinical models predicted; this could be due to the limitations of the GBM models employed. Once this is addressed, and we develop effective gene therapies in models that better replicate the clinical scenario, gene therapy will provide a powerful approach to treat and manage brain tumors.
A perspective on pancreatic stem/progenitor cells (2004)

The prevalence of both type 1 and type 2 diabetes mellitus is increasing throughout the world along with the ensuant morbidity and early mortality because of premature microvascular and macrovascular disease. Current insulin and drug therapies control diabetes, but do not cure it. Cell-based therapies offer the possibilities of a permanent cure for diabetes. Recently, success in the transplantation of pancreatic islets in the livers of type 1 diabetics has afforded the opportunity for a potential cure. However, the severe shortage of donor islets for transplantation limits the usefulness of this therapy. One approach is to exploit the use of stem cells, either embryo-derived or adult tissue-derived, as substrates to create islet tissue suitable for transplantation. Cells isolated from embryo blastocysts and from adult pancreas, liver, and bone marrow can be expanded extensively in vitro and differentiated into islet-like clusters that produce insulin, and, in some instances, can achieve glycemic control when transplanted into streptozotocin-induced diabetic mice. It is, now, also possible to envision the direct systemic administration of stem cells that would home in on and regenerate injured islets, or to administer stem cell stimulators that would enhance endogenous pancreatic stem cells to expand and differentiate into functional, insulin-producing beta-cells. This perspective discusses the potential applications of cellular medicines, in the new discipline of regenerative medicine, to achieve a cure for diabetes.
Overview of autofeed: an unsupervised learning system for generating webfeeds (2006)

The AutoFeed system automatically extracts data from semi-structured web sites. Previously, researchers have developed two types of supervised learning approaches for extracting web data: methods that create precise, site-specific extraction rules and methods that learn less-precise site-independent ex-traction rules. In either case, significant training is required. AutoFeed follows a third, more ambitious approach, in which unsupervised learning is used to analyze sites and discover their structure. Our method relies on a set of heterogeneous “experts”, each of which is capable of identifying certain types of generic structure. Each expert represents its discov-eries as “hints”. Based on these hints, our system clusters the pages and identifies semi-structured data that can be ex-tracted. To identify a good clustering, we use a probabilistic model of the hint-generation process. This paper summarizes our formulation of the fully-automatic web-extraction prob-lem, our clustering approach, and our results on a set of ex-periments.
Blood pressure-lowering effect of extract from Lactobacillus casei in spontaneously hypertensive rats(SHR). (1990)

The effects of oral administration of hot water extract from autologous lysate of Lactobadllus casei (LEx) on the systolic blood pressure (SBP) were studied in spontaneously hypertensive rats (SHR). Oral doses of 10 mg/kg of LEx produced a significant decrease of the SBP of SHR, but LEx had no effect in normotensive rats. The long-term administration of LEx (1 or 10 mg/kg/day) to SHR from 5 to 17 weeks after birth suppressed the development of hypertension. LEx dialysed against distilled water was separated into a polysaccharide fraction (SG-1), a protein fraction (PR-1), and a nucleic acid fraction (NA-1), and SBP-lowering effects of these materials were investigated in SHR at the same dose (10 mg/kg). The most effective material of these three was SG-1.
Low frequency portable lightweight sonar systems and their method of deployment for greatly increasing the efficiency of submarine surveillance over large areas (1987)

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Nanoscale liquid crystal polymer Bragg polarization gratings (2017)

We experimentally demonstrate nearly ideal liquid crystal (LC) polymer Bragg polarization gratings (PGs) operating at a visible wavelength of 450 nm and with a sub-wavelength period of 335 nm. Bragg PGs employ the geometric (Pancharatnam-Berry) phase, and have many properties fundamentally different than their isotropic analog. However, until now Bragg PGs with nanoscale periods (e.g., < 800 nm) have not been realized. Using photo-alignment polymers and high-birefringence LC materials, we employ multiple thin sublayers to overcome the critical thickness threshold, and use chiral dopants to induce a helical twist that effectively generates a slanted grating. These LC polymer Bragg PGs manifest 85-99% first-order efficiency, 19-29° field-of-view, Q ≈ 17, 200 nm spectral bandwidth, 84° deflection angle in air (in one case), and efficient waveguide-coupling (in another case). Compared to surface-relief and volume-holographic gratings, they show high efficiency with larger angular/spectral bandwidths and potentially simpler fabrication. These nanoscale Bragg PGs manifest a 6π rad/μm phase gradient, the largest reported for a geometric-phase hologram while maintaining a first-order efficiency near 100%.
Three-dimensional PSF characterization of circle-plus-arc cone-beam computed tomography (2005)

Cone-beam CT (CBCT) realizes true three-dimensional (3D) imaging in terms of its direct volume reconstruction with isotropic resolution. However, the 3D imaging performance of a CBCT system is spatially variant (or non-uniform) over the support domain, which can be quantitatively characterized by 3D point spread function (PSF). The CBCT system PSF can be experimentally measured through the use of telfon ball and edge-spread technique. For a single circular scan orbit, its volume reconstruction fails to meet data sufficiency condition, consequently causing spatial shift variance. In the pursuit of meeting data sufficiency condition, we have proposed a circle-plus-arc CB scan scheme. The overall CBCT imaging process involves several factors, including x-ray source, cone-beam projection, and computational reconstruction; each factor can in principle be characterized by a convolution kernel or PSF. In this paper, we concentrate on the PSF characterization of circle-plus-arc algorithm. Based on the linearity of Radon transform and inverse Radon transform, we can partition the Radon domain. In particular, the circle-plus-arc scan scheme partitions the Radon domain into a donut-like region (associated with the circle scan) and funnel-like null region (provided by the arc scan). A modified FDK algorithm is responsible for donut region reconstruction, and a filtered-backprojection-styled inverse Radon transform is for the null region reconstruction. By adding them up, we obtain the complete volume reconstruction. Through the use of a bead array phantom (a 5×5×5 array), subject to cone-beam scan under different scan patterns and volume reconstruction, we calculated the local PSF blurs and the spatial variance. The result shows that, for our CBCT simulation with 28 degree cone angle, the circle scan produces a spatial variance of 9.3% and the circle-plus-arc scan reduces that to 1.8%.
Subunit stoichiometry of the pancreatic β‐cell ATP‐sensitive K<sup>+</sup> channel (1997)

We have investigated the subunit stoichiometry of the pancreatic beta-cell ATP-sensitive K+ (KATP) channel (SUR1/Kir6.2 channel) by constructing cDNA encoding a single polypeptide (beta alpha polypeptide) consisting of a SUR1 (beta) subunit and a Kir6.2 (alpha) subunit. 86Rb+ efflux and single-channel properties of COS1 cells expressing beta alpha polypeptides were similar to those of COS1 cells coexpressing alpha monomers and beta monomers. Coexpression of beta alpha polypeptides with alpha monomers inhibited the K+ currents, while coexpression with beta monomers did not. We then constructed another single polypeptide (beta alpha2) consisting of a beta subunit and a dimeric repeat of the alpha subunit. 86Rb+ efflux from COS1 cells expressing beta alpha2 polypeptides was small, but was restored by supplementation with beta monomers. These results indicate that the activity of K(ATP) channels is optimized when the alpha and beta subunits are coexpressed with a molar ratio of 1:1. Since inward rectifier K+ channels are thought to function as homo- or hetero-tetramers, this suggests that the K(ATP) channel functions as a multimeric protein, most likely a hetero-octamer composed of a tetramer of the Kir6.2 subunit and a tetramer of the SUR1 subunit.
A Smart Sensing Cannula for Fat Grafting (2019)

Gluteal fat grafting has been highlighted as a significant safety issue in plastic surgery, with a mortality rate as high as one in 3000 cases. Injury to the gluteal veins resulting in fat emboli has been identified as the cause of these mortalities. The gluteal veins lie deep to the gluteal musculature in the buttocks, and it has been suggested that avoiding intramuscular injection of fat may prevent these complications. The authors present a novel injection cannula design that uses impedance sensing to determine the location of the cannula tip. Specifically, the system can determine when the tip of the cannula leaves the subcutaneous plane and enters muscle. The use of this system may prevent inadvertent injury to the gluteal veins and subsequent embolic complications. CLINICAL QUESTION/LEVEL OF EVIDENCE:: Therapeutic, V.
An eight-dimensional trellis code (1986)

An 8-state trellis code is described that uses a signal constellation from the 8-dimensional Gosset lattice E <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">8</inf> . It can be used for example to transmit data at 9.6, 14.4, and 19.2 kbits/s with a nominal coding gain of close to 6 dB.