gebhart/patrepeval huggingface dataset:
A Lateral Retinacular Imbrication Technique for the Surgical Correction of Anterior Cruciate Ligament Rupture in the Dog (1970)

SUMMARY A lateral retinacular imbrication technique was used to repair rupture of the anterior cruciate ligament in 57 stifles in 50 dogs during a 15-month period. Forty-two stifles in 37 dogs were evaluated from 2 to 13 months postoperatively. Medial patellar luxation coexisted with rupture of the anterior cruciate ligament in 12 of the stifles and was also corrected at the time of surgery. The results were satisfactory in 85.7% of the cases evaluated (36 of 42 stifles). The success rate was higher (92.6%, or 25 of 27 stifles) in cases complicated by coexisting pathologic conditions of the stifle.
High-speed high-precision min/max circuits in CMOStechnology (2000)

New voltage-mode min/max circuits are introduced that have a simple architecture. Unlike conventional winner-take-all or source follower based schemes, the proposed circuits are characterised by reduced voltage swing at all internal nodes and by a very low output impedance, which enables them to provide high-speed and high-precision operation. Their complexity grows linearly with the number of inputs. The characterisation of a test chip prototype has provided experimental verification of these features.
The Role of Ion Mobility Spectrometry–Mass Spectrometry in the Analysis of Protein Reference Standards (2013)

To achieve comparability of measurement results of protein amount of substance content between clinical laboratories, suitable reference materials are required. The impact on measurement comparability of potential differences in the tertiary and quaternary structure of protein reference standards is as yet not well understood. With the use of human growth hormone as a model protein, the potential of ion mobility spectrometry-mass spectrometry as a tool to assess differences in the structure of protein reference materials and their interactions with antibodies has been investigated here.
Measuring RF circuits response using software defined radio system (2014)

Four basic methods for measuring RF circuit frequency response were implemented and tested on the popular software defined radio system based on popular GNU-radio software package and on the Ettus USRP hardware. Properties, advantages and disadvantages of this solution were studied and are described in this paper. Using the proposed platform for measurement is interesting, because the equipment needed is much cheaper than standard test tools and can be used for educational or research purposes, where long time or intensive measurements was needed.
Recursive Principal Component Analysis-Based Data Outlier Detection and Sensor Data Aggregation in IoT Systems (2017)

Internet of Things (IoT) is emerging as the underlying technology of our connected society, which enables many advanced applications. In IoT-enabled applications, information of application surroundings is gathered by networked sensors, especially wireless sensors due to their advantage of infrastructure-free deployment. However, the pervasive deployment of wireless sensor nodes generate massive amount of sensor data, and data outliers are frequently incurred due to the dynamic nature of wireless channels. As operation of IoT systems relies on sensor data, data redundancy and data outliers could significantly reduce the effectiveness of IoT applications or even mislead systems into unsafe conditions. In this paper, a cluster-based data analysis framework is proposed using recursive principal component analysis (R-PCA), which can aggregate the redundant data and detect the outliers in the meantime. More specifically, at a cluster head, spatially correlated sensor data collected from cluster members are aggregated by extracting the principal components (PCs), and potential data outliers are determined by the abnormal squared prediction error score, which is defined as the square of residual value after extraction of PCs. With R-PCA, the parameters of PCA model can be recursively updated to adapt to the changes in IoT systems. Cluster-based data analysis framework also releases the computational and processing burdens on sensor nodes. Practical databases-based simulations have confirmed that the proposed framework efficiently aggregates the correlated sensor data with high recovery accuracy. The data outlier detection accuracy is also improved by the proposed method compared to other existing algorithms.
Correlative In Vivo 2 Photon and Focused Ion Beam Scanning Electron Microscopy of Cortical Neurons (2013)

Correlating in vivo imaging of neurons and their synaptic connections with electron microscopy combines dynamic and ultrastructural information. Here we describe a semi-automated technique whereby volumes of brain tissue containing axons and dendrites, previously studied in vivo, are subsequently imaged in three dimensions with focused ion beam scanning electron microcopy. These neurites are then identified and reconstructed automatically from the image series using the latest segmentation algorithms. The fast and reliable imaging and reconstruction technique avoids any specific labeling to identify the features of interest in the electron microscope, and optimises their preservation and staining for 3D analysis.
Modeling and analysis of extrusion-spin coating : an efficient and deterministic photoresist coating method in microlithography (2001)

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 2001.
All-optical wavelength conversion and broadcasting to eight separate channels by a single semiconductor optical amplifier delay interferometer (2003)

We have demonstrated an all-optical broadcast experiment in which a 10 Gbit/s RZ data signal is simultaneously converted into up to 8 different wavelengths. A single SOA with delay interferometer was used. Bit error rate measurements showed a power penalty of less than 1.5 dB for configurations with up to 8 wavelengths.
Asymmetric Ring-Closing Metathesis Catalyzed by Chiral Molybdenum Alkylidene Complexes (1998)

Kinetic resolution was observed in ring-closing metathesis of racemic dienes catalyzed by the newly developed chiral molybdenum alkylidene complexes (R,R)-Mo(CHCMe(2)Ph)(NAr)(TBEC) 1 (Ar = 2,6-i-Pr(2)C(6)H(3), TBEC = 2',2',2",2"-tetrakis(trifluoromethyl)-1,2-bis(2'-hydroxyethyl)cyclopentane) and (R,R)-Mo(CHCMe(2)Ph)(NAr)(TBEH) 2 (Ar = 2,6-i-Pr(2)C(6)H(3), TBEH = 2',2',2",2"-tetrakis(trifluoromethyl)-1,2-bis(2'-hydroxyethyl)cyclohexane). In the case of a prochiral symmetric triene substrate, optically active cyclized product was formed by catalytic ring-closing metathesis with 1, which opens the possibility of a new version of two-directional synthesis. Although the observed enantiomeric excesses were modest to low, this data demonstrates the feasibility of asymmetric induction by chiral alkylidene catalysts in ring-closing metathesis.
Road-quality classification and bump detection with bicycle-mounted smartphones (2013)

The paper proposes a embedded surface road classifier for smartphones used to track and classify routes on bikes. The main idea is to provide, along with the route tracking, information about surface quality of the cycling route (is the surface smooth, rough or bumpy?). The main problem is the quantity of accelerometer data that would have to be uploaded along with GPS track, if the analysis was done off-line. Instead, we propose to classify road surfaces online with an embedded classifier, that has been trained off-line. More specifically, we rely on the accelerometer of a bicycle-mounted smartphone for online classification. We carry out experiments to collect cycling tracks consisting of GPS and accelerometer data, label the data and learn a model for classification, which again is deployed on the smartphone. We report on our experiences with classification accuracy on and runtime performance of the classifier on the smartphone. 1
The Plant Phenolic Compound <i>p</i> -Coumaric Acid Represses Gene Expression in the <i>Dickeya dadantii</i> Type III Secretion System (2008)

The type III secretion system (T3SS) is a major virulence factor in many gram-negative bacterial pathogens. This secretion system translocates effectors directly into the cytosol of eukaryotic host cells, where the effector proteins facilitate bacterial pathogenesis by interfering with host cell signal transduction and other cellular processes. Plants defend themselves against bacterial pathogens by recognizing either the type 3 effectors or their actions and initiating a cascade of defense responses that often results in programmed cell death of the plant cell being attacked. Here we show that a plant phenolic compound, p-coumaric acid (PCA), represses the expression of T3SS genes of the plant pathogen Dickeya dadantii, suggesting that plants can also defend against bacterial pathogens by manipulating the expression of the T3SS. PCA repressed the expression of T3SS regulatory genes through the HrpX/Y two-component system, a core regulator of the T3SS, rather than through the global regulator GacS/A, which indirectly regulates the T3SS. A further analysis of several PCA analogs suggests that the para positioning of the hydroxyl group in the phenyl ring and the double bond of PCA may be important for its biological activity.
Preliminary evaluation of a wireless remote monitoring system for home mechanical ventilation (2016)

Patients who have acute respiratory failure and who have not responded to other treatment options can benefit from using a treatment, called Home Mechanical Ventilation. In order to allow the remote patient monitoring, in the last few years several tele-monitoring systems have been introduced, but most of them usually do not allow real-time services, are based on a wired connection, have their own proprietary serial communication protocol implemented and some ventilation parameters are not always measured. In order to reduce the above quoted drawbacks, in this work we report the development of a novel wireless remote monitoring system for long-term home-based ventilation therapy. The proposed system is based on the real-time monitoring of the main physical quantities involved during home-care ventilation and is developed in order to allow observation of different remote therapy units everywhere located in different places of a city, region or country. The developed remote patient monitoring system has been successfully tested by means of spirometric trials and, especially, by means of experimental tests carried out with pulmonary ventilators typically used to support sick patients.
USING PERMUTATIONS TO FIND STRUCTURAL CHANGES IN TIME SERIES (2010)

The number of permutations appearing in data series is used for detecting changes in the structure of such series. We show the influence of the permutations length (embedding dimension) in order to get good results. We use permutations to analyze real data from medical and biological origins. Some problems that appear in applying these techniques are pointed out.
Effects of ozone in normal human epidermal keratinocytes (2013)

Ozone is a tropospheric pollutant that can form at ground level as a result of an interaction between sunlight and hydrocarbon engine emissions. As ozone is an extremely oxidative reaction product, epidermal cells are in the outer layer of defense against ozone. We exposed normal human epidermal keratinocytes (NHEK) to concentrations of ozone that have been measured in cities and assayed for its effects. Hydrogen peroxide and IL-1α levels both increased while ATP levels decreased. We found a decrease in the NAD-dependent histone deacetylase, sirtuin 3. Lastly, we found that ozone increased DNA damage as evaluated by Comet assay. Taken together, our results show increased damage to NHEK that will ultimately impair normal cellular function as a result of an environmentally relevant ozone exposure.
Error-Free Tunable Dispersion Slope Compensation for 40-Gb/s WDM Systems Using Non-Channelized 3 rd -Order Chirped Fiber Bragg Gratings (2002)

We demonstrate tunable dispersion slope compensation for 40-Gb/s WDM systems using two inverse 3rd-order chirped gratings. The inherent errors in a single grating are eliminated. The slope range is -20 to +20 ps/nm2over a 5-nm bandwidth.
The Selective Cyclooxygenase-2 Inhibitor Nimesulide Prevents <b> <i>Helicobacter pylori</i> </b>-Associated Gastric Cancer Development in a Mouse Model (2004)

Our data show that nimesulide prevents H. pylori-associated gastric carcinogenesis, and suggest that COX-2 may be a target for chemoprevention of gastric cancer.
A 19.1-dBm Fully-Integrated 24 GHz Power Amplifier Using 0.18-¿m CMOS Technology (2008)

A 24 GHz, 19.1 dBm fully-integrated power amplifiers (PA) was designed and fabricated in the 0.18-iquestm deep n-well (DNW) CMOS technology. This power amplifier is a 2-stage design using cascode RF NMOS configuration and has a maximum measured output power of 19.1 dBm, an OP <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1dB</sub> of 13.3 dBm, a power added efficiency (PAE) of 15.6%, and a linear gain of 18.8 dB when V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">DD</sub> and DNW are both biased at 3.6 V. The chip size is only 0.56 times 0.58 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . To the author's knowledge, this PA demonstrates the highest output power of +19.1 dBm among the reported PAs above 15 GHz in CMOS processes.
Placement-based partitioning for lookup-table-based FPGAs (2003)

Lookup-table-based field-programmable gate array (FPGA) logic blocks contain multiple lookup-tables, flip flops, and other features. The partitioning of this logic into physical blocks has a logical component, traditionally handled as part of technology mapping in logic synthesis, and a physical component, traditionally handled by placement in physical design. However, methods that use a purely logical partitioning give designs that are difficult to route, and methods that use a purely physical partitioning do not result in legal logical blocks. The authors describe a partitioning method that includes both logic-based and placement-based steps to achieve a high-quality legal partitioning. The method simultaneously generates an initial placement for the design.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
AUTOMATIC TOPIC SEGMENTATION AND LABELING IN MULTIPARTY DIALOGUE (2006)

This study concerns how to segment a scenario-driven multiparty dialogue and how to label these segments automatically. We apply approaches that have been proposed for identifying topic boundaries at a coarser level to the problem of identifying agenda-based topic boundaries in scenario-based meetings. We also develop conditional models to classify segments into topic classes. Experiments in topic segmentation show that a supervised classification approach that combines lexical and conversational features outperforms the unsupervised lexical chain-based approach, achieving 20% and 12% improvement on segmentating top-level and sub-topic segments respectively. Experiments in topic classification suggest that it is possible to automatically categorize segments into appropriate topic classes given only the transcripts. Training with features selected using the Log Likelihood ratio improves the results by 13.3%.
Electromagnetic tracker for active handheld robotic systems (2016)

We describe the development of the In-Loop Electromagnetic Tracker (ILEMT), designed to meet the demanding latency and resolution requirements for active stabilization of hand motion during precision manipulations such as microsurgery. The prototype surpasses the fastest commercial EM trackers by > 4× in root bandwidth/resolution and 2× in latency. The use of two widely spaced carrier frequencies (e.g., 300 Hz and 10 kHz) enables a particularly simple way of reducing the eddy-current interference caused by nonferrous metals present in the workspace. Previously, metal compatibility has only been achieved at a large cost to measurement speed.
State-of-the-Science Review of Transtibial Prosthesis Alignment Perturbation (2009)

In Brief A systematic review of research on the effects of transtibial prosthesis alignment perturbation on gait was carried out following guidelines prepared by the American Academy of Orthotists and Prosthetists. Approximately 278 references published since 1973 were obtained by searching key data bases and then screened for relevance, resulting in 34 published research articles, which were evaluated for internal and external validity using published criteria and assigned ratings of high, moderate, or low. A matrix was developed that classified the 34 articles by the type of alignment perturbations undertaken and the outcome measures used. The matrix used eight categories of perturbations and 43 distinct outcomes measures related to the total body, gait symmetry, EMG and oxygen consumption, and kinematic and kinetic measurements of the prosthetic and contralateral limb. These articles were used to generate 113 evidence statements pertaining to the effect of alignment perturbation on gait. Each of the statements was assigned a confidence rating of high, moderate, low, or insufficient evidence based on the volume and quality of the published evidence. Forty-three statements judged to have high or moderate levels of confidence associated with them are presented and discussed, along with recommendations concerning future research on alignment perturbation studies. A systematic review of research on the effects of transtibial prosthesis alignment perturbation on gait was carried out following guidelines prepared by the American Academy of Orthotists and Prosthetists. Forty-three statements judged to have High or Moderate levels of confidence associated with them are presented and discussed, along with recommendations concerning future research on alignment perturbation studies.
Aspects of Polar-Coded Modulation (2013)

We consider the joint design of polar coding and higher-order modulation schemes for ever increased spectral efficiency. The close connection between the polar code construction and the multi-level coding approach is described in detail. Relations between different modulation schemes such as bit-interleaved coded modulation (BICM) and multi-level coding (MLC) in case of polar-coded modulation as well as the influence of the applied labeling rule and the selection of frozen channels are demonstrated.
Non-rigid full torso respiratory motion correction of SPECT studies (2010)

Respiratory motion artifact is one of the factors limiting the diagnostic accuracy of SPECT or PET. Full-torso respiratory motion correction in general requires non-rigid respiratory motion estimation and correction due to different organs moving at different rates and possibly directions. In work we presented a method to reduce noise and equalize organ counts in SPECT, to aid non-rigid motion estimation via registration. This is done by transforming the intensities by a function which reduces the noise variance as well as brings the different organ counts to similar levels. We also address the issue of uneven counts in different respiratory states as done in our previous work when addressing rigid registration of the heart for Cardiac SPECT. Then we perform affine registration and B-spline-based free-form deformation on the transformed datasets to obtain the motion estimates. We incorporate the motion estimates within MLEM reconstruction for motion correction as done previously. We applied the method to four actual patient acquisitions. For all four patient datasets we found differences and improvements after corrections. We are also investigating our methodology with NCAT phantom simulations where the truth is know. The NCAT we use was modified to have non-rigid organ motion with respiration.
<p>Immunotherapy for Medulloblastoma: Current Perspectives</p> (2020)

From our review, we suggest that cancer vaccines, oncolytic viral therapy, natural killer cells, and CAR T therapy hold promise against the innate immunosuppressive properties of medulloblastoma in order to prolong survival. There is an unmet need for immunotherapy regimens that target overexpressed antigens in medulloblastoma tumors. We advocate for more combination treatment clinical trials using conventional surgical and radiochemotherapy approaches in the near-term clinical development.
Fault propagation characteristics analysis for large-scale electronic system by hierarchical signed directed graph (2015)

A qualitative model based on hierarchical signed directed graph (HSDG) is built to analyze the fault propagation characteristics in large scale electronic systems. Compared with the traditional single layer SDG model, the HSDG has combined the topology structure information into the model, and the diagnosis inference process can be implemented hierarchically, which can reduce the fault root cause searching area and make the diagnosis process more efficient. Besides, the structure of the HSDG model is closer to the structure of the real system and the reasoning process is easier to explain, which makes it more suitable to solve the fault propagation analysis and fault diagnosis tasks for large-scale electronic systems. Experimental results on an actual satellite central control system show that the HSDG can describe the fault propagation characteristics of the system and find the fault root cause effectively.
Review article: potential mechanisms of action of rifaximin in the management of hepatic encephalopathy and other complications of cirrhosis (2015)

The gut microenvironment and associated microbiota play an important role in the pathogenesis of HE and other cirrhosis-related complications. Rifaximin's clinical activity may be attributed to effects on metabolic function of the gut microbiota, rather than a change in the relative bacterial abundance.
Exceptionally high trans (anti) stereoselectivity in catalytic cyclopropanation reactions (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTExceptionally high trans (anti) stereoselectivity in catalytic cyclopropanation reactionsMichael P. Doyle, Vahid Bagheri, Thomas J. Wandless, Nancy K. Harn, David A. Brinker, Cassandra T. Eagle, and Kuo Liang LohCite this: J. Am. Chem. Soc. 1990, 112, 5, 1906–1912Publication Date (Print):February 1, 1990Publication History Published online1 May 2002Published inissue 1 February 1990https://pubs.acs.org/doi/10.1021/ja00161a040https://doi.org/10.1021/ja00161a040research-articleACS PublicationsRequest reuse permissionsArticle Views2745Altmetric-Citations196LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts