gebhart/patrepeval huggingface dataset:
64.5L: <i>Late‐News Paper</i> : Large Area Flexible Display of Fiber OLED (2006)

Abstract For the production of large area display, we have proposed a concept of “one‐dimensional substrate” instead of the large sized glass plate. Each of TFT and OLED has fabricated on a glass fiber which consists of a column in the display. It has also pointed out that the production scheme called Reel‐to‐Reel (RtR) has been required, which is completely different from the conventional process. In this paper, we describe an alternative of the original, which uses ribbon fiber and confined RtR processes only to OLED. The TFT fiber should be replaced by Si chips. This would enable more rapid progress for the development of the one‐dimensional technologies. In addition the technologies will be applied to lighting.
Better outcome of adult acute lymphoblastic leukemia after early genoidentical allogeneic bone marrow transplantation (BMT) than after late high-dose therapy and autologous BMT: a GOELAMS trial (2004)

Various transplantation strategies have been designed to improve the poor prognosis of adult (ages 15 to 60 years) acute lymphoblastic leukemia (ALL). The GOELAL02 trial evaluated the impact of early allogeneic bone marrow transplantation (alloBMT) or delayed unpurged autologous stem cell transplantation (ASCT) for patients who had no human leukocyte antigen (HLA)-matched sibling donor or who were older than 50 years. Inclusion criteria included at least one of the following: age older than 35 years; non-T-ALL; leukocytosis greater than 30 x 10(9)/L; t(9;22), t(4;11), or t(1; 19); or failure to achieve complete remission (CR) after one induction course. Among 198 patients, the median age was 33 years. The CR rate was 80% with vincristine, idarubicine, L-asparaginase, and randomized intravenous injection or oral steroids (P = nonsignificant [ns]). AlloBMT was performed after 2 consolidation courses while ASCT was delayed after 1 additional reinduction. Intensified conditioning regimen before transplantation included etoposide, cyclophosphamide, and total body irradiation (TBI). Median follow-up was 5.1 years. The median overall survival (OS) was 29 months, with a 6-year OS of 41%. On an intent-to-treat analysis for patients younger than 50 years, alloBMT significantly improved the 6-year OS (75% versus 40% after ASCT; P = .0027). Randomized interferon-alpha maintenance had no effect on relapse or survival after ASCT. In conclusion, the outcome of adult ALL is better after early alloBMT than after delayed ASCT.
Performance-Oriented Partitioning for Task Scheduling of Parallel Reconfigurable Architectures (2014)

Dynamic reconfiguration is important for reconfigurable platforms. Parallel reconfigurable computing (PRC) architecture consists of multiple dynamic reconfigurable computing (DRC) units. Thus, for a circuit to be implemented on a parallel reconfiguration system, it needs to be partitioned such that each sub-circuit can be executed to the DRC units in a PRC system. For high performance, this paper proposes a greedy algorithm that maximizes data parallelism for task scheduling of parallel reconfigurable architectures with unlimited resources. The proposed algorithm generates an optimal solution in polynomial time <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex Notation="TeX">$O(n^{3})$</tex> <mathgraphic fileref="kao-ieq1-2312924.gif" graphicformat="GIF"/></formula> , where <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex Notation="TeX"> $n$</tex><mathgraphic fileref="kao-ieq2-2312924.gif" graphicformat="GIF"/></formula> is the total number of the tasks. After obtaining a depth optimal solution, we reduce the resources without decreasing performance by the duplication packing operations whose time complexity is <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex Notation="TeX">$O(n^{3})$</tex> <mathgraphic fileref="kao-ieq3-2312924.gif" graphicformat="GIF"/></formula> . To demonstrate the performance of the proposed algorithm, we not only compare the existing methods with standard benchmarks but also implement on physical systems, like DSP, FIR, and JPEG. The experimental results show that the proposed algorithms satisfy the requirements of the performance-oriented systems with limited resources. Hence, we have sufficient reason to believe that the runtime must be reasonable for general applications.
OCCURRENCE <italic>IN VIVO</italic> OF 5-HYDROXYTRYPTOPHOL IN THE BRAIN OF RATS TREATED WITH ETHANOL (1992)

The effect of ethanol (EtOH) on the release of dopamine (DA) and 5-hydroxytryptamine (5-HT) and the efflux of their metabolites, 3,4-dihydroxyphenylacetic acid (DOPAC), 5-hydroxyindol-3-ylacetic acid (5-HIAA) and 5-hydroxytryptophol (5-HTOL) from the striatum of the freely moving rat were studied in vivo using brain microdialysis. Striatal DA and 5-HT release was maximally enhanced at first fraction after the administration of EtOH (2 g/kg, i.p.). The level of the DA-oxidized metabolite, DOPAC, decreased significantly. In the 5-HT metabolic pathway, the oxidized metabolite, 5-HIAA, did not show significant changes, whereas levels of the biogenic alcohol 5-HTOL were increased to 180% at 90 min following EtOH administration. It is suggested that EtOH, most probably via acetaldehyde, could shift 5-HT metabolism from the oxidative to the reductive pathway in the rat brain.
Cell Cycle Regulators and Mechanisms of Growth Control Evasion in Lung Cancer (1998)

The last several years have seen an explosion in our understanding of the components and mechanisms involved in regulation of the eukaryotic cell cycle. The explosion began with the discovery of cyclins and the identification of Xenopus maturation promoting factor as a complex of cyclin B and a cdc2-related protein kinase [1]. Since then cyclins and the cyclindependent kinases (CDKs) have been identified as the key mediators of cell cycle progression, and the cast of known players has expanded to include cyclins A, B1, B2, C, D1-3, E, F, G, H, and I and CDKs 1–7, as well as inhibitors and mediators of CDK activity [2-5].
Phosphorylation of Fascin Decreases the Risk of Poor Survival in Patients With Esophageal Squamous Cell Carcinoma (2010)

Phosphorylation of fascin at serine 39 (phospho-S39-fascin) could inhibit its actin-binding and actin-bundling activities and decrease filopodia formation. However, the relationship between phospho-S39-fascin expression and clinicopathological parameters in tumors is still unknown. Here, Western blot analysis and IHC applied to tissue microarray technology were performed to examine the expression status of non-phosphorylated fascin (fascin) and phospho-S39-fascin and their impacts on the prognosis of patients with esophageal squamous cell carcinoma (ESCC). Fascin and phospho-S39-fascin expressions were tested by cytoplasmic staining. Among the 254 patients, 90 cases showed high expression of fascin and 87 cases showed high expression of phospho-S39-fascin. Survival analysis showed that high expression of fascin was significantly associated with a poor prognosis of the patients with ESCC (p=0.004). In contrast, high expression of phospho-S39-fascin correlated significantly with an improved outcome of patients (p=0.020). Multivariate analysis showed that both fascin and phospho-S39-fascin were independent prognostic factors. In a combined analysis, the patients with high expression of fascin and low expression of phospho-S39-fascin tumors had a shorter overall survival than those with high expression of both fascin and phospho-S39-fascin tumors (5-year overall survival rate: 28.7% vs 48.3%, p=0.068). Our results suggest that high expression of fascin correlates with poor outcome and that high expression of phospho-S39-fascin decreases the risk of poor prognosis in ESCC. This manuscript contains online supplemental material at http://www.jhc.org. Please visit this article online to view these materials.
Evidence for Dirac Fermions in a Honeycomb Lattice Based on Silicon (2012)

Silicene, a sheet of silicon atoms in a honeycomb lattice, was proposed to be a new Dirac-type electron system similar to graphene. We performed scanning tunneling microscopy and spectroscopy studies on the atomic and electronic properties of silicene on Ag(111). An unexpected √3 × √3 reconstruction was found, which is explained by an extra-buckling model. Pronounced quasiparticle interferences (QPI) patterns, originating from both the intervalley and intravalley scatter, were observed. From the QPI patterns we derived a linear energy-momentum dispersion and a large Fermi velocity, which prove the existence of Dirac fermions in silicene.
Large scale active-learning-guided exploration for in vitro protein production optimization (2020)

Lysate-based cell-free systems have become a major platform to study gene expression but batch-to-batch variation makes protein production difficult to predict. Here we describe an active learning approach to explore a combinatorial space of ~4,000,000 cell-free buffer compositions, maximizing protein production and identifying critical parameters involved in cell-free productivity. We also provide a one-step-method to achieve high quality predictions for protein production using minimal experimental effort regardless of the lysate quality.
Symbolic execution for BIOS security (2015)

We are building a tool that uses symbolic execution to search for BIOS security vulnerabilities including dangerous memory references (call outs) by SMM interrupt handlers in UEFI-compliant implementations of BIOS. Our tool currently applies only to interrupt handlers for SMM variables. Given a snapshot of SMRAM, the base address of SMRAM, and the address of the variable interrupt handler in SMRAM, the tool uses S2E to run the KLEE symbolic execution engine to search for concrete examples of a call to the interrupt handler that causes the handler to read memory outside of SMRAM. This is a work in progress. We discuss our approach, our current status, our plans for the tool, and the obstacles we face.
High-Precision Latency Forwarding over Packet-Programmable Networks (2020)

New emerging network applications such as Industry 4.0, haptic applications, and holographic-type communications will require support for stringent end-to-end latency objectives with precisely specified lower and upper bounds. These requirements will push current best-effort Internet technology and QoS mechanisms to their limit. This paper presents a new approach to achieve high-precision latency objectives, carrying latency objectives as part of packet metadata and taking differentiated actions at network nodes depending on a packet’s remaining latency budget, its destination, and the latency encountered so far. A Proof-of-Concept has been developed using BPP, a novel programmable networking framework.
Seamless Handoff and Performance Anomaly Reduction Schemes Based on OpenFlow Access Points (2014)

The enterprise WLANs that are composed of multiple access points (APs) and AP controller, provide wireless backbone networks in the building and campus. In this paper, we propose the Open Flow AP system that is a software-defined enterprise WLAN system based on the Open Flow-based AP and the Open Flow controller. Also, we propose the seamless handoff and performance anomaly reduction schemes based on the Open Flow AP system in order to improve total throughput of the networks while user experience is guaranteed. We deployed the Open Flow AP system in the lab building and performed several experiments to evaluate the efficiency of the proposed system and applications. When the proposed system is compared with the existing WLANs, it performs handoff seamlessly without reassociation and increases total throughput of the network by 26.7% when client is located in overlapped service area.
Insights on the Mechanism of Insoluble-to-Soluble Prussian Blue Transformation (2009)

The electrochemical transformation of the soluble form of Prussian blue (PB) material from the insoluble form was monitored using electrochemical, gravimetric, acoustic, and spectroscopic techniques simultaneously. The described combination of in situ techniques represents an innovative tool for measurement in electrochemistry, which provides complementary information on the electrochemical systems. The insoluble-to-soluble PB transformation process takes place during the successive voltammetric cycles between the mixed valence form (PB) and the fully reduced form [Everitt's salt (ES)]. One of the processes that takes place is the exit of free ions occluded in the vacancies of the insoluble PB crystalline framework during the fresh PB electrodeposit process. In potassium salt solutions, the exit of each ferrocyanide ion is compensated by the entrance of two potassium ions and six hydroxyl anions. This species exchange increases the manifestation of viscoelastic phenomena of the rigid skeleton from the insoluble PB form to the soluble one, which could facilitate the appearance of an internal magnetic field at room temperature during the soluble voltammetric cycle.
Microwave imaging of moving subjects by combined use of video-tracker and multi-static radar (2015)

This paper presents preliminary experiments with a geometrically simple target and a new architecture of the microwave screening system capable of obtaining radar images of moving subjects. The system is based on the combined use of a video-tracker and a linear antenna array. Inverse synthetic aperture is formed by arbitrary motion of the target in the vicinity of the array. A video-based system tracks the target and allows coherent processing of synchronously registered radar data, and eventually obtaining detailed radar images of concealed objects.
Antibacterial Properties of Silicone Membranes after a Simple Two-Step Immersion Process in Iodine and Silver Nitrate Solutions (2018)

Silicone is widely used in packing materials, medical equipment, and separation membranes. Since microbial cells easily adhere to the surface of silicone materials and form biofilms, techniques for incorporating antimicrobial activity into silicone materials are in high demand. This study describes the preparation of silver (Ag)/silicone composite membranes through a simple two-step immersion process, utilizing an iodine solution followed by a silver nitrate solution at room temperature. Scanning electron microscopy (SEM) observations revealed that particles with sizes of several nanometers to several tens of nanometers were present on the silicone membrane surface; these particles were identified as silver iodide using energy-dispersive X-ray spectroscopy (EDS) . The Ag/silicone membrane possessed excellent antibacterial efficacy against Escherichia coli and Staphylococcus aureus, and the antibacterial efficacy (R) against both types of bacteria was R > 4, even after stomacher treatment or acidic treatment of pH 2-6 for 24 h. The mechanical strength of the silicone membrane was also maintained after antibacterial treatment, with Young's modulus values of 7.9±1.2 MPa and 8.3±1.5 MPa for the untreated membrane and Ag/silicone membrane, respectively (p > 0.05) . In addition, the reduction in permeation performance of the Ag/silicone membrane was only 20%, despite the antibacterial treatment on the membrane surface. This antibacterial treatment method of silicone membranes can be conducted at room temperature (25℃) without special equipment, and may be applied to other types of silicone materials.
X-ray Compton backscattering techniques for process tomography: imaging and characterization of materials (1996)

Non-destructive evaluation by Compton scattering using an industrial x-ray tube allows three-dimensional (3D) imaging of materials. The x-ray tube and the detector are set on the same side of the object. Thus, non-destructive evaluation of the wall of a tank, even when it is full, is possible without the requirement for the x-ray beam to cross the whole object. Several applications were tried in our laboratory. Besides 3D imaging, a method allowing thickness measurement of a wall was developed, which was especially suitable for multilayer compounds. The accuracy is mm. Compton scattering techniques also allow point-by-point density measurements in the near-surface zone of any component (even dense and bulky ones). An accuracy of 1% was achieved for light composite materials and also for dense components () provided by powder metallurgy. A new application allows us to perform 3D imaging using a linear accelerator (6 MeV) as the photon source. Thus, testing can be performed inside a tank, even through a thick and dense wall (8 mm of steel).
Modeling a Helical-coil Steam Generator in RELAP5-3D for the Next Generation Nuclear Plant (2011)

Options for the primary heat transport loop heat exchangers for the Next Generation Nuclear Plant are currently being evaluated. A helical-coil steam generator is one heat exchanger design under consideration. Safety is an integral part of the helical-coil steam generator evaluation. Transient analysis plays a key role in evaluation of the steam generators safety. Using RELAP5-3D to model the helical-coil steam generator, a loss of pressure in the primary side of the steam generator is simulated. This report details the development of the steam generator model, the loss of pressure transient, and the response of the steam generator primary and secondary systems to the loss of primary pressure. Back ground on High Temperature Gas-cooled reactors, steam generators, the Next Generation Nuclear Plant is provided to increase the readers understanding of the material presented.
1,2,4-Triazole-Based Tunable Aryl/Alkyl Ionic Liquids (2010)

Ionic liquids based on aryl-/alkyl-substituted imidazolium salts constitute a new generation of ionic liquids with a high degree of flexibility. The new concept could now also be extended to aryl-/alkyl-substituted 1,2,4-triazolium salts. The two different phenyl-substituted 1H- and 4H-1,2,4-triazoles have been synthesized by a coupling reaction or a one-pot synthesis with diformylhydrazine, respectively. Reaction with alkyl bromides provided the 1,2,4-triazolium bromides, and an anion-exchange reaction led to the corresponding bis(trifluoromethylsulfonyl)imide salts with melting points well below 100 °C.
Specific Contributions of the Small GTPases Rho, Rac, and Cdc42 to Dbl Transformation (1999)

Dbl is a representative prototype of a growing family of oncogene products that contain the Dbl homology/pleckstrin homology elements in their primary structures and are associated with a variety of neoplastic pathologies. Members of the Dbl family have been shown to function as physiological activators (guanine nucleotide exchange factors) of the Rho-like small GTPases. Although the expression of GTPase-defective versions of Rho proteins has been shown to induce a transformed phenotype under different conditions, their transformation capacity has been typically weak and incomplete relative to that exhibited by dbl-like oncogenes. Moreover, in some cases (e.g. NIH3T3 fibroblasts), expression of GTPase-defective Cdc42 results in growth inhibition. Thus, in attempting to reconstitute dbl-induced transformation of NIH3T3 fibroblasts, we have generated spontaneously activated ("fast-cycling") mutants of Cdc42, Rac1, and RhoA that mimic the functional effects of activation by the Dbl oncoprotein. When stably expressed in NIH3T3 cells, all three mutants caused the loss of serum dependence and showed increased saturation density. Furthermore, all three stable cell lines were tumorigenic when injected into nude mice. Our data demonstrate that all three Dbl targets need to be activated to promote the full complement of Dbl effects. More importantly, activation of each of these GTP-binding proteins contributes to a different and distinct facet of cellular transformation.
Differentiation of Neisseria gonorrhoeae from other Neisseria species by use of the restriction endonuclease HaeIII (1984)

We used the restriction endonuclease HaeIII to differentiate Neisseria gonorrhoeae from other Neisseria species and Branhamella catarrhalis. A total of 16 clinical isolates and four American Type Culture Collection strains of N. gonorrhoeae were resistant to HaeIII digestion, whereas 17 isolates and four American Type Culture Collection strains from eight different bacterial species were susceptible. This resistance was not caused by an enzyme inhibitor. We propose that protection of the HaeIII recognition sequence by methylation is the mechanism of resistance since N. gonorrhoeae DNA became susceptible to digestion when passed in Escherichia coli as part of a plasmid clone.
Novel Receiver Architecture for LTE-A Downlink Physical Control Format Indicator Channel with Diversity (2014)

Physical control format indicator channel (PCFICH) carries the control information about the number of orthogonal frequency division multiplexing (OFDM) symbols used for transmission of control information in long term evolution-advanced (LTE-A) downlink system. In this paper, two novel low complexity receiver architectures are proposed to implement the maximum likelihood- (ML-) based algorithm which decodes the CFI value in field programmable gate array (FPGA) at user equipment (UE). The performance of the proposed architectures is analyzed in terms of the timing cycles, operational resource requirement, and resource complexity. In LTE-A, base station and UE have multiple antenna ports to provide transmit and receive diversities. The proposed architectures are implemented in Virtex-6 xc6vlx240tff1156-1 FPGA device for various antenna configurations at base station and UE. When multiple antenna ports are used at base station, transmit diversity is obtained by applying the concept of space frequency block code (SFBC). It is shown that the proposed architectures use minimum number of operational units in FPGA compared to the traditional direct method of implementation.
High Lithium Transference Number Electrolytes via Creation of 3-Dimensional, Charged, Nanoporous Networks from Dense Functionalized Nanoparticle Composites (2013)

High lithium transference number, tLi+, electrolytes are desired for use in both lithium-ion and lithium metal rechargeable battery technologies. Historically, low tLi+ electrolytes have hindered device performance by allowing ion concentration gradients within the cell, leading to high internal resistances that ultimately limit cell lifetime, charging rates, and energy density. Herein, we report on the synthesis and electrochemical features of electrolytes based on nanoparticle salts designed to provide high tLi+. The salts are created by cofunctionalization of metal oxide nanoparticles with neutral organic ligands and tethered lithium salts. When dispersed in a conducting fluid such as tetraglyme, they spontaneously form a charged, nanoporous network of particles at moderate nanoparticle loadings. Modification of the tethered anion chemistry from −SO3– to −SO3BF3– is shown to enhance ionic conductivity of the electrolytes by facilitating ion pair dissociation. At a particle volume fraction of 0.15, the electrolyte exists as a self-supported, nanoporous gel with an optimum ionic conductivity of 10–4 S/cm at room temperature. Galvanostatic polarization measurements on symmetric lithium metal cells containing the electrolyte show that the cell short circuit time, tSC, is inversely proportional to the square of the applied current density tSC ∼ J–2, consistent with previously predicted results for traditional polymer-in-salt electrolytes with low tLi+. Our findings suggest that electrolytes with tLi+ ≈ 1 and good ion-pair dissociation delay lithium dendrite nucleation and may lead to improved lithium plating in rechargeable batteries with metallic lithium anodes.