gebhart/patrepeval huggingface dataset:
Forward Dynamics, Elimination Methods, and Formulation Stiffness in Robot Simulation (1997)

The numerical simulation problem of tree-structured multi body systems, such as robot manipulators, is usually treated as two separate problems: 1) the forward dynamics problem for computing system accelerations, and 2) the numerical integra tion problem for advancing the state in time. The interaction of these two problems can be important, and has led to new conclusions about the overall efficiency of multibody simula tion algorithms (Cloutier, Pai, and Ascher 1995). In particular, the fastest forward dynamics methods are not necessarily the most numerically stable, and in ill-conditioned cases may slow down popular adaptive step-size integration methods. This phenomenon is called formulation stiffness. In this article, we first unify the derivation of both the com posite rigid-body method (Walker and Orin 1982) and the articulated-body method (Featherstone 1983, 1987) as two elimination methods for solving the same linear system, with the articulated-body method taking advantage of sparsity. Then the numerical instability phenomenon for the composite rigid- body method is explained as a cancellation error that can be avoided, or at least minimized, when using an appropriate version of the articulated-body method. Specifically, we show that a variant of the articulated-body method is better suited to deal with certain types of ill-conditioning than the composite rigid-body method. The unified derivation also clarifies the un derlying linear algebra of forward dynamics algorithms, and is therefore of interest in its own right.
Adaptation of oxyanionic sigmatropy to the convergent enantioselective synthesis of ambergris-type odorants (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAdaptation of oxyanionic sigmatropy to the convergent enantioselective synthesis of ambergris-type odorantsRobert E. Maleczka Jr. and Leo A. PaquetteCite this: J. Org. Chem. 1991, 56, 23, 6538–6546Publication Date (Print):November 1, 1991Publication History Published online1 May 2002Published inissue 1 November 1991https://pubs.acs.org/doi/10.1021/jo00023a018https://doi.org/10.1021/jo00023a018research-articleACS PublicationsRequest reuse permissionsArticle Views451Altmetric-Citations28LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Erfahrungen mit Phytophthora de Bary und Pythium Pringsheim (1985)

von Heinz Krober ; herausgegeben von der Biologischen Bundesanstalt fur Land- und Forstwirtschaft Berlin-Dahlem
Phenotype correction of fanconi anemia group a hematopoietic stem cells using lentiviral vector (2003)

Fanconi anemia (FA) is an autosomal recessive disease characterized by progressive bone marrow failure due to defective stem cell function. FA patients' cells are hypersensitive to DNA cross-linking agents such as mitomycin C (MMC), exposure to which results in cytogenetic aberrations and cell death. To date Moloney murine leukemia virus vectors have been used in clinical gene therapy. Recently, third-generation lentiviral vectors based on the HIV-1 genome have been developed for efficient gene transfer to hematopoietic stem cells. We generated a self-inactivating lentiviral vector expressing the FA group A cDNA driven by the murine stem cell virus U3 LTR promoter and used the vector to transduce side-population (SP) cells isolated from bone marrow of Fanconi anemia group A (Fanca) knockout mice. One thousand transduced SP cells reconstituted the bone marrow of sublethally irradiated Fanca recipient mice. Phenotype correction was demonstrated by stable hematopoiesis following MMC challenge. Using real-time PCR, one proviral vector DNA copy per cell was detected in all lineage-committed cells in the peripheral blood of both primary and secondary recipients. Our results suggest that the lentiviral vector transduces stem cells capable of self-renewal and long-term hematopoiesis in vivo and is potentially useful for clinical gene therapy of FA hematopoietic cells.
Mitigating Bias in Algorithmic Hiring: Evaluating Claims and Practices (2023)

chapter Share on Mitigating Bias in Algorithmic Hiring: Evaluating Claims and Practices Author: Manish Raghavan Massachusetts Institute of Technology, Sloan School of Management and Department of Electrical Engineering and Computer Science Massachusetts Institute of Technology, Sloan School of Management and Department of Electrical Engineering and Computer ScienceView Profile Authors Info & Claims The Societal Impacts of Algorithmic Decision-MakingSeptember 2023https://doi.org/10.1145/3603195.3603203Published:08 September 2023Publication History 0citation0DownloadsMetricsTotal Citations0Total Downloads0Last 12 Months0Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Adhesive and Friction Forces between Chemically Modified Silicon and Silicon Nitride Surfaces (1998)

We report the results of probing adhesion and friction forces between surfaces with functional terminal groups with chemically modified scanning probe microscopy (SPM) tips. Surfaces with terminal groups of CH3, NH2, and SO3H were obtained by direct chemisorption of silane-based compounds on silicon/silicon nitride surfaces. We studied surface properties of the resulting self-assembled monolayers (SAMs) in air and aqueous solutions with different pHs. Work of adhesion, “residual forces”, and friction coefficients was obtained for four different types of modified tips and surfaces. Absolute values of the work of adhesion between various surfaces, Wad, were in the range 0.5−8 mJ/m2. The work of adhesion for different modified surfaces correlated with changes of solid−liquid surface energy estimated from macroscopic contact-angle measurements. Friction properties varied with pH in a register with adhesive forces showing a broad maximum at intermediate pH values for a silicon nitride/silicon nitride mating pair. Similar broad maxima were observed in the acid range for a NH2-terminated SAM and in the basic range for a SO3H-terminated SAM. This behavior can be understood considering the changes of the surface charge state determined by the zwitterionic nature of silicon nitride surfaces with multiple isoelectric points.
The geographic cluster of microcalcifications of the breast. (1985)

During a period of two years, nine patients were found who had a solitary geographic cluster of microcalcifications which appeared to be intramammary on two standard mammographic views. In two instances, the women underwent unsuccessful excisional biopsies. In the other seven patients, the true location of the microcalcifications was recognized and proved preoperatively so biopsy was avoided. When intradermal microcalcifications are fortuitously imaged in tangent or when they assume characteristic polygonal shapes with lucent centers, their intradermal location should be suspected. However, if the form is not typical of intradermal calcifications and when the location appears to be intramammary on the routine mammographic views, an excisional biopsy will usually be recommended. If skin is not included in the excised tissue, then the biopsy will be unsuccessful. A simple technique using a metallic marker can confirm the true intradermal location of calcifications.
GROWTH COMPANIES (1995)

Changes in the product sector translate to a scaling back of revenue expectations and new hiring plans.
Development of high-density interconnection techniques for contactless smart cards (2002)

Summary form only given. This paper deals with techniques that are used for fabricating high density and thin assemblies with emphasis on materials, implementation and reliability. Moreover, a new potential interconnection and packaging technique being particularly suitable for contacting ultra-thin chips is also introduced. In the production tests electroless fine-pitch Ni/Au bumped chips were bonded with solder paste but the results were not satisfactory. Commercial isotropically and anisotropically conductive adhesives allowing denser interconnections than conventional soldering gave markedly better results and are now used in volume production of contactless cards. A new type of ACA containing fusible filler particles was employed for bonding flip chip bumps on the substrate with metallurgically compatible contact pads. The results proved to be very promising especially from the electrical continuity point of view. A solderless interconnection technique, which is especially suitable for producing very fine pitch interconnections, was employed successfully for fabricating contactless smart cards. In this technique, in which the substrate conductors are chemically deposited on shallow bumps of the embedded chips, high reliability of the interconnections can be achieved.
Stopping criteria for regression testing in GUI application using failure intensity and failure reliability (2015)

We propose some criteria for GUI regression testing to determine the appropriate time to stop without wasting too much testing cost. This is essential for all software upgrades that can be released in a reasonably short time, yet still guarantees the product quality. One difficulty to achieve such a target depends on the sequence of test cases being input. The order affects the number of found failures. As such, the proposed methodology randomizes the order of test cases into different sequences for the regression test input. When a failure is found, it is edited immediately before the test resumes. Performance of the proposed criteria encompasses three measures, namely, failure intensity, cost of testing and editing, and reliability. The reliability function incorporates Weibull distribution to better reflect the test data. The proposed methodology is tested using real GUI applications as test data and shows satisfactory results on stopping criteria.
Conjugated Linoleic Acid Reduces Body Weight and Body Fat in Postmenopausal Women with Type 2 Diabetes (2008)

Post‐menopausal women are at risk for weight gain and type 2 diabetes (T2DM). Conjugated linoleic acid (CLA) reduces fat mass in mice, but results in humans have been inconsistent. In a 36‐ week controlled, double masked, crossover study we sought to determine if CLA reduces body weight and alters body composition. Fifty‐ five subjects were randomized into two groups, receiving 6.4 g mixed isomer CLA and 1.6 g safflower oil (SAF) or 8.0g SAF daily Analysis of results at individual 5% level of significance were as follows. Mean body weight loss in the CLA group was 0.48 ±0.23 kg in diet period one (DP1) and 0.42± 0.19 kg in diet period two (DP2). Body mass index (BMI) was significantly lower with CLA compared to SAF during both diet periods, with a trend toward weight loss after 8 weeks of supplementation. Body fat mass (BFM) was significantly lower in the CLA group without changes in lean body mass (LBM). SAF did not affect BFM, while SAF increased LBM in both diet periods. There was no evidence of change in sagittal abdominal diameter or waist‐ to‐ hip ratio, indexes of visceral obesity. The changes in BMI and BFM were not associated with dietary energy intake. Reports of adverse events did not differ between groups. In conclusion, CLA given at a dose of 6.4g/day over a 16 week period causes a significant reduction in BMI and BFM while preserving LBM in obese postmenopausal women with T2DM. Supported by Cognis GmbH
Prediction of ceramic stereolithography resin sensitivity from theory and measurement of diffusive photon transport (2005)

A general, quantitative relationship between the photon-transport mean free path (l*) and resin sensitivity (DP) in multiple-scattering alumina/monomer suspensions formulated for ceramic stereolithography is presented and experimentally demonstrated. A Mie-theory-based computational method with structure factor contributions to determine l* was developed. Planar-source diffuse transmittance experiments were performed on monodisperse and bimodal polystyrene/water and alumina/monomer systems to validate this computational tool. The experimental data support the application of this l* calculation method to concentrated suspensions composed of nonaggregating particles of moderately aspherical shape and log-normal size distribution. The values of DP are shown to be approximately five times that of l* in the tested ceramic stereolithography suspensions.
First 3D Imaging Results with the MIMO Radar of RAWIS (2018)

This paper presents first 3D imaging results of the main radar system of the Radar Warning and Information System for Applications in Disaster Management (RAWIS) which will support in the future search and rescue teams in disaster areas. The main radar of RAWIS is a planar MIMO (Multiple-Input and Multiple-Output) array and consists of 24 transmit and 32 receive elements. For far field conditions 768 independent virtual elements can be synthesized. By using change detection methods, small changes in the scene - like moving debris - can be detected with sub-mm accuracy.
Parallel Processing and Applied Mathematics. 10th International Conference, PPAM 2013. Revised Selected Papers (2014)

The following topics are dealt with: parallel scientific computing; numerical algorithms; parallel nonnumerical algorithms; cloud computing; evolutionary computing; metaheuristics; applied mathematics; GPU computing; multicore systems; hybrid architectures; hierarchical parallelism; HPC systems; power monitoring; energy monitoring; and distributed computing.
Eradication by active specific immunotherapy of established tumor transplants and microscopic lymph node metastases. (1982)

Guinea pigs, each with an established syngeneic dermal line 10 tumor and microscopic lymph node metastases, were immunized by injection of a mixture of irradiated line 10 tumor cells and an oil-in-water emulsion containing heat-killed cells of Mycobacterium bovis strain Bacillus Calmette-Guérin. Squalane or squalene-in-water emulsions, prepared by ultrasonication and containing mg doses of mycobacterial cells, were effective adjuvants. Immunization eradicated established dermal tumors (about 10 mm in diameter) and prevented growth of microscopic lymph node metastases. Untreated animals, animals treated by intradermal administration of Bacillus Calmette-Guérin cells attached to oil droplets alone or with irradiated tumor cells alone, all died with progressive tumor growth.
Same-Sex Harassment after Boh Brothers (2016)

Because Equal Employment Opportunity Commission v. Boh Brothers Construction Company ostensibly represents the first faithful application of the gender-stereotyping theory in the context of same-sex harassment litigation, additional courts may elect to abandon the objective-evidence standard in favor of adopting the Fifth Circuit’s subjective-perception test. Employers, therefore, must resist the temptation to dismiss Boh Brothers as a legal aberration confined to the Fifth Circuit and instead take steps to prepare for the possibility of a legal environment in which overtly masculine men and patently feminine women may assert viable same-sex harassment claims. By eliminating the requirement that harassees exhibit readily observable, objectively gender-nonconforming characteristics in the workplace while at the same time mandating that courts conduct a rigorous, fact-intensive inquiry into the idiosyncratic beliefs and perceptions of individual harassers, the subjective-perception test would seem to portend a significant expansion of employer liability.
EDA-Fibronectin Originating from Osteoblasts Inhibits the Immune Response against Cancer (2016)

Osteoblasts lining the inner surface of bone support hematopoietic stem cell differentiation by virtue of proximity to the bone marrow. The osteoblasts also modify their own differentiation by producing various isoforms of fibronectin (FN). Despite evidence for immune regulation by osteoblasts, there is limited knowledge of how osteoblasts modulate cells of the immune system. Here, we show that extra domain A (EDA)-FN produced by osteoblasts increases arginase production in myeloid-derived cells, and we identify α5β1 as the mediating receptor. In different mouse models of cancer, osteoblasts or EDA-FN was found to up-regulate arginase-1 expression in myeloid-derived cells, resulting in increased cancer growth. This harmful effect can be reduced by interfering with the integrin α5β1 receptor or inhibiting arginase. Conversely, in tissue injury, the expression of arginase-1 is normally beneficial as it dampens the immune response to allow wound healing. We show that EDA-FN protects against excessive fibrotic tissue formation in a liver fibrosis model. Our results establish an immune regulatory function for EDA-FN originating from the osteoblasts and identify new avenues for enhancing the immune reaction against cancer.
CHARACTERIZATION OF A PROMOTER REARRANGEMENT AND A SECOND PROMOTER IN THE HUMAN C-MYB PROTO-ONCOGENE (1993)

The human cellular proto-oncogene c-myb has been implicated as important in the regulation of hematopoietic cell growth and differentiation. Aberrant expression of this gene and chromosomal aberrations near the c-myb locus have been associated with a number of carcinogenic processes. An alternatively spliced CDNA clone of c-myb, pMbm-2, contains unique 5’ sequences which replace exon 1. The existence of this 5’ divergent CDNA clone led us into a study of the promoter activity of the c-myb gene. Intron 1 of c-myb is highly conserved between human and mouse throughout the intron, while only those sequences directly adjacent to exons 1 and 2 are conserved between human and chicken. The unique sequence of pMbm-2 was located directly adjacent to exon 2, suggesting that it arose as a product of alternative transcription initiation within intron 1. A cluster of transcription start sites was detected at the 5’ end of exon 2. Levels of messages utilizing these start sites are expressed proportionally to those arising from the primary promoter. Functional characterization of this region revealed that this region can function as a promoter. Deletion studies have revealed the presence of negative and positive regulatory elements within this region which are utilized with different efﬁciencies in different cell lines. These studies suggest that cis or trans factors acting in this region may serve a dual function in both attenuation and transcription initiation. Studies of the c-myb promoter utilizing the acute lymphoblastic cell line CCRF-CEM revealed that a portion of the c-myb promoter is lost in this cell line. The rearranged locus, which we have designated MRR (myb rearranged region), has been Cloned and mapped to chromosome 6. The MR sequence is linked to the c-myb locus, suggesting that the rearrangement is due to a submicroscopic deletion. The rearrangement appears to have no effect on c-myb promoter activity as analyzed in CCRF-CEM cells. The normal locus of the MRR sequence shows a high degree of homology to a member of the myc family of oncogenes. Therefore, although attenuation may be the primary mechanism of c-myb regulation, the existence of a second promoter in the c-myb gene and a rearrangement of the primary c-myb promoter in a leukemia cell line suggests that other regions at the 5’ end of this gene are important in the regulation of c-myb transcription.
ACS NEWS COMMENT (1985)

RETURN TO ISSUEPREVACS NewsNEXTACS NEWS COMMENTBYANT W. ROSSITERView Author Information chairman Committee on International ActivitiesCite this: Chem. Eng. News 1985, 63, 15, 27–28Publication Date (Print):April 15, 1985Publication History Published online7 November 2010Published inissue 15 April 1985https://pubs.acs.org/doi/10.1021/cen-v063n015.p027https://doi.org/10.1021/cen-v063n015.p027acs-newsACS PublicationsCopyright © 1985 AMERICAN CHEMICAL SOCIETY. This publication is available under these Terms of Use. This publication is free to access through this site. Learn MoreArticle Views92Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (182 KB) SUBJECTS:Continuing education Get e-Alerts
Implementation of low-cost laser range finder with object tracking function (2017)

In the space or plane, the coordinate of object is important in industrial application, like 3D measurement, reverse engineering and robot calibration. But it is hard to verify expect a laser tracker. In this study, a tracking system had been built by motion control card, servo motor, laser range finder and position sensing detector. PSD was placed on the object and keep laser beam locks on the origin of PSD to accomplish tracking. The system can apply on coordinate and track measure and reduce the cost compare with laser interferometer or laser tracker.
Operation and intrinsic error budget of a two-qubit cross-resonance gate (2019)

A relevant quantum gate for building a superconducting quantum computer is extensively analyzed. The limitations for achieving high gate fidelities due to several physical mechanisms are established, which may promote further experimental explorations.
A GaN-based flying-capacitor multilevel boost converter for high step-up conversion (2016)

Compact high step-up DC/DC conversion to provide high DC voltage has numerous applications. A conventional boost converter has many limitations with regard to achieving high voltage gain with high power density and efficiency. The flying-capacitor multilevel (FCML) converter topology has many inherent advantages to overcome many of the limitations of the conventional boost converter. In this work, a GaN-based 7-level flying capacitor multilevel boost converter prototype has been implemented and achieved 100 V to 914 V conversion at 750 W output power with 92.7% peak efficiency, and 200 V to 966 V conversion at 900 W output power with 93.7% peak efficiency within the tested load range.