gebhart/patrepeval huggingface dataset:
The use of space discretization for autonomous virtual humans (video session) (1998)

No abstract available.
DIGICERT: A Secured Digital Certificate Application using Blockchain through Smart Contracts (2019)

Deception of Certificates is the major issue that is faced by the educational sector. In order to prevent forgery of certificates and to provide a secure certificate verification environment an authenticated system application is developed using blockchain with smart contracts. The immutability property of blockchain prevents the data stored from being manipulated and helps in implementing a verification system. The system generates a new block for every user in the blockchain. These blockchain are replicated across all the nodes involved in a Peer-to-Peer network and thus it improves the reliability of the system. Whenever a user is validated, their certificates are digitally provided by the system to the user along with a Quick Response code. This helps in sharing of certificates between the employers. The authenticity of certificates is improved by embedding the certificates with imperceptible watermark using the alpha blending process. This helps to avoid various attacks at different phases of certificate distribution.
Reactivity of Pb(II) at the Mn(III,IV) (Oxyhydr)Oxide−Water Interface (2001)

In this study, the reactivity of lead (Pb(II)) on naturally occurring Mn(III,IV) (oxyhydr)oxide minerals was evaluated using kinetic, thermodynamic, and spectroscopic investigations. Aqueous Pb(II) was more strongly adsorbed to birnessite (delta-MnO1.7) than to manganite (gamma-MnOOH) under all experimental conditions. The isoteric heat of Pb adsorption (delta HT) or birnessite was 94 kJ mol-1 at a surface loading of 1.1 mmol g-1, and decreased with increasing adsorption density. This indicated that adsorption was an endothermic process and that birnessite possessed heterogeneous sites of reactivity for Pb. X-ray absorption fine structure (XAFS) spectra revealed that Pb was adsorbed as inner-sphere complexes on both birnessite and manganite with no evidence to suggest oxidation as an operative sorption mechanism. Lead appeared to coordinate to vacancy sites in the birnessite layer structure with concurrent release of Mn to solution, which resulted in a greater number of second shell Mn scatterers in Pb-birnessite when compared to Pb-manganite samples. The difference in Pb coordination apparently explained the contrasting desorption behavior between the two Mn minerals. These results have significant implications for Pb partitioning in soil environments containing solid-phase Mn(III,IV) (oxyhydr)oxides.
Security Vulnerabilities of the NDEF Signature Record Type (2011)

The NFC Forum has released a first candidate for their Signature Record Type Definition. This specification adds digital signatures to the NFC Data Exchange Format (NDEF), which is a standardized format for storing formatted data on NFC (Near Field Communication) tags and for transporting data across a peer-to-peer links between NFC devices. With an increasing number of applications of the NFC and NDEF technology, more and more security threats became apparent. The signature record type is supposed to increase security for NDEF application by providing authenticity and integrity to the NDEF data. This paper takes a close look on the recently published Signature Record Type Definition and discusses its various security aspects. First, we introduce the signature record type and its usage. After that, we analyze the security aspects of the current signature method. Finally, we disclose multiple security vulnerabilities of the current Signature Record Type Definition and propose measures to avoid them.
Long-Range Indoor Navigation With PRM-RL (2020)

Long-range indoor navigation requires guiding robots with noisy sensors and controls through cluttered environments along paths that span a variety of buildings. We achieve this with PRM-RL, a hierarchical robot navigation method in which reinforcement learning (RL) agents that map noisy sensors to robot controls learn to solve short-range obstacle avoidance tasks, and then sampling-based planners map where these agents can reliably navigate in simulation; these roadmaps and agents are then deployed on robots, guiding them along the shortest path where the agents are likely to succeed. In this article, we use probabilistic roadmaps (PRMs) as the sampling-based planner, and AutoRL as the RL method in the indoor navigation context. We evaluate the method with a simulation for kinematic differential drive and kinodynamic car-like robots in several environments, and on differential-drive robots at three physical sites. Our results show that PRM-RL with AutoRL is more successful than several baselines, is robust to noise, and can guide robots over hundreds of meters in the face of noise and obstacles in both simulation and on robots, including over 5.8 km of physical robot navigation.
Development of Display Ads Retrieval System to Match Publisher's Contents (2013)

The technological transformation and automation of digital content delivery has revolutionized the media industry. Advertising landscape is gradually shifting its traditional media forms to the emergent of Internet advertising. In this paper, the types of internet advertising to be discussed on are contextual and sponsored search ads. These types of advertising have the central challenge of finding the best match between a given context and a suitable advertisement, through a principled method. Furthermore, there are four main players that exist in the Internet advertising ecosystem: users, advertisers, ad exchange and publishers. Hence, to find ways to counter the central challenge, the paper addresses two objectives: how to successfully make the best contextual ads selections to match to a web page content to ensure that there is a valuable connection between the web page and the contextual ads. All methods, discussions, conclusion and future recommendations are presented as per sections. Hence, in order to prove the working mechanism of matching contextual ads and web pages, web pages together with the ads matching system are developed as a prototype.
Pressure measurement of air cushions for patients (2003)

Pressure sores are a serious problem for patients with spinal cord injuries (SCI). Many kinds of pressure-relieving cushions have been developed to distribute the weight widely. In rehabilitation medicine, the selection of the wheelchair cushion and the adjustment of the cushion are very important problem for the medical staff in prevention of pressure sores. So we propose a radar chart to support the medical staff. We believe that this radar chart is very useful to the medical staff in selecting the wheelchair cushions, adjusting the cushions and assisting the SCl patient's posture. Moreover, it is useful for the SCI patients to study their posture on the wheelchair and the prevention of pressure sores.
Designing a Novel Ternary Multiplier Using CNTFET (2014)

Today, multipliers are included as substantial keys of many systems with high efficiency such as FIR filters, microprocessors and processors of digital signals.
Isolation and Characterization of a cDNA from Cell Suspension Cultures of Vanilla planifolia Andr. Encoding 4-Coumarate:CoA Ligase (1997)

Isolation and Characterization of a cDNA from Cell Suspension Cultures of Vanilla planifolia Andr. Encoding 4-Coumarate:CoA Ligase
Virtualizing the Assessment: A Novel Pragmatic Paradigm to Evaluate Lower Extremity Joint Perception in Diabetes (2012)

The findings demonstrate proof of a concept of virtual-reality application as a promising method for objective assessment of neuropathy severity, however a further study is warranted to establish a stronger relationship between the measured parameters and neuropathy.
Full length cDNA sequence of porcine secreted phosphoprotein-I (SPP-I, osteopontin) (1989)

Journal Article Full length cDNA sequence of porcine secreted phosphoprotein-I (SPP-I, osteopontin) Get access Jeffrey L. Wrana, Jeffrey L. Wrana * MRC Group in Periodontal Physiology, Room 4384 Medical Sciences Building, University of TorontoToronto M5S 1A8, Canada *To whom correspondence should be addressed Search for other works by this author on: Oxford Academic PubMed Google Scholar Qi Zhang, Qi Zhang MRC Group in Periodontal Physiology, Room 4384 Medical Sciences Building, University of TorontoToronto M5S 1A8, Canada Search for other works by this author on: Oxford Academic PubMed Google Scholar Jaro Sodek Jaro Sodek MRC Group in Periodontal Physiology, Room 4384 Medical Sciences Building, University of TorontoToronto M5S 1A8, Canada Search for other works by this author on: Oxford Academic PubMed Google Scholar Nucleic Acids Research, Volume 17, Issue 23, 11 December 1989, Page 10119, https://doi.org/10.1093/nar/17.23.10119 Published: 11 December 1989 Article history Accepted: 16 October 1989 Published: 11 December 1989
<title>Preparation and properties of fully solid state electrochromic display thin film from a sol-gel process</title> (1997)

Fully solid state electrochromic displays (ECD) have been prepared several times. But, they all needed more than 1 minute to complete coloring or breaching. Electrochromism of amorphous material is expected to be faster than that of crystalline one by its faster diffusion coefficients of ions due to the open structure. In this study, electrochromic films and a gel electrolyte were made by a sol-gel process using metal salts and alkoxide as raw materials. Tungsten oxide, iridium oxide films and a gel electrolyte were used to fabricate a fully solid state ECD (electrode/tungsten oxide/gel electrolyte/iridium oxide/electrode) and it electrochromic properties were investigated. Crystalline and amorphous tungsten oxide and iridium oxide films were prepared on soda lime silica glass substrates sputter-coated with indium tin oxide (ITO). Electrochromic properties of amorphous WO3 film were more significant than that of crystalline one. On the other hand, electrochromic properties of amorphous iridium oxide film were less than crystalline one. The ECD showed reversible transmittance modulation of 35% (at 800 nm, film thickness: tungsten oxide 400 nm, iridium oxide 200 nm) under alternative voltage apply of plus or minus 3 V for 0.2 sec. The ECD kept the same transmittance modulation during 200 color-breach cycles.© (1997) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
Embedded CELP coding for variable bit-rate between 6.4 and 9.6 kbit/s (1991)

The authors consider the design of a variable-bit-rate CELP (code-excited linear prediction) coder which incorporates the facility of producing an embedded bit stream. This characteristic is particularly attractive for packet transmission where some packets can be lost or rejected whenever they are not received within the maximum allowed delay. The basic scheme used for the investigations is a CELP coder in which the innovation signal is split into three separate contributions. The sum of all contributions, together with the side information, determines the operating bit rate of 9.6 kb/s. The reduced bit rates of 8 and 6.4 kb/s can be achieved, dropping respectively the information relevant to one or two contributions to the innovation signal.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Relaxed-Rigidity Constraints: In-Grasp Manipulation using Purely Kinematic Trajectory Optimization (2017)

This paper proposes a novel approach to performing in-grasp manipulation planning: the problem of moving an object with reference to the palm from an initial pose to a goal pose without breaking or making contacts. Our method to perform in-grasp manipulation uses kinematic trajectory optimization which requires no knowledge of dynamic properties of the object or the robot. We define a cost function that attempts to maintain the initial grasp points, while relaxing the constraint that the contacts between finger and object remain rigid. Hence, we name this new formulation relaxed-rigidity constraints. We implement our approach on an Allegro robot hand and perform experiments on 10 objects from the YCB dataset. However, the implementation would work for any object the robot can grasp. We perform thorough analysis and compare to alternative optimization formulations. Our method reaches the desired object pose with a median position error of 13mm across all of the 500 trials without ever dropping the object.
Impulse-Based Rendering Methods for Haptic Simulation of Bone-Burring (2011)

Bone-burring is a common procedure in orthopedic, dental, and otologic surgeries. Virtual reality (VR)-based surgical simulations with both visual and haptic feedbacks provide novice surgeons with a feasible and safe way to practice their burring skill. However, creating realistic haptic interactions between a high-speed rotary burr and stiff bone is a challenging task. In this paper, we propose a novel interactive haptic bone-burring model based on impulse-based dynamics to simulate the contact forces, including resistant and frictional forces. In order to mimic the lateral and axial burring vibration forces, a 3D vibration model has been developed. A prototype haptic simulation system for the bone-burring procedure has been implemented to evaluate the proposed haptic rendering methods. Several experiments of force evaluations and task-oriented tests were conducted on the prototype system. The results demonstrate the validity and feasibility of the proposed methods.
Bacteria-free minicircle DNA system to generate integration-free CAR-T cells (2018)

BF minicircle vector will be useful in basic research as well as in clinical applications such as CAR-T and gene therapy. Although the transgene expression of minicircle vector lasts apparently shorter than that of insertional lentivirus, multiple rounds of BF minicircle CAR-T cell infusion could eliminate cancer cells efficiently. On the other hand, a relatively shorter CAR-T cell persistence provides an opportunity to avoid serious side effects such as cytokine storm or on-target off-tumour toxicity.
Poly(ADP-ribosyl)ation is involved in the epigenetic control of<i>TET1</i>gene transcription (2014)

TET enzymes are the epigenetic factors involved in the formation of the sixth DNA base 5-hydroxymethylcytosine, whose deregulation has been associated with tumorigenesis. In particular, TET1 acts as tumor suppressor preventing cell proliferation and tumor metastasis and it has frequently been found down-regulated in cancer. Thus, considering the importance of a tight control of TET1 expression, the epigenetic mechanisms involved in the transcriptional regulation of TET1 gene are here investigated. The involvement of poly(ADP-ribosyl)ation in the control of DNA and histone methylation on TET1 gene was examined. PARP activity is able to positively regulate TET1 expression maintaining a permissive chromatin state characterized by DNA hypomethylation of TET1 CpG island as well as high levels of H3K4 trimethylation. These epigenetic modifications were affected by PAR depletion causing TET1 down-regulation and in turn reduced recruitment of TET1 protein on HOXA9 target gene. In conclusion, this work shows that PARP activity is a transcriptional regulator of TET1 gene through the control of epigenetic events and it suggests that deregulation of these mechanisms could account for TET1 repression in cancer.
Dynamically De-Skewable Clock Distribution Methodology (2008)

In a typical clock distribution scheme, a central clock signal is distributed to several sites on the integrated circuit (IC). Local regenerators at these sites buffer the clock signal for the logic in regions close to the regenerator. Minimizing the skew between the clocks at these regeneration sites is critical. In recent times, this is becoming harder due to increasing intra-die processing variations. In this paper, we describe a novel technique to distribute a clock signal from a central location to several sites on a VLSI IC. Our technique uses a buffered H-tree and includes circuitry to dynamically remove any skew that may result due to intra-die processing variations. While existing approaches to deskewing a clock tree have utilized several phase detection circuits (number of phase detectors dependent on the number of clock regenerators), our method requires only one phase detector. Also, in our approach, the resolution of the phase detector is inconsequential unlike existing techniques. Our deskewing technique can be applied dynamically, either at boot time or periodically during the operation of the IC. Using a six-level H-tree clock distribution network with process variations deliberately included, we demonstrate that our technique can reduce skews as high as 300 ps down to just 3 ps. We compare our clock tree with traditional buffered and unbuffered H-tree networks.
Applications of indocyanine green in brain tumor surgery: review of clinical evidence and emerging technologies (2021)

Indocyanine green (ICG) is a water-soluble dye that was approved by the FDA for biomedical purposes in 1956. Initially used to measure cardiocirculatory and hepatic functions, ICG's fluorescent properties in the near-infrared (NIR) spectrum soon led to its application in ophthalmic angiography. In the early 2000s, ICG was formally introduced in neurosurgery as an angiographic tool. In 2016, the authors' group pioneered a novel technique with ICG named second-window ICG (SWIG), which involves infusion of a high dose of ICG (5.0 mg/kg) in patients 24 hours prior to surgery. To date, applications of SWIG have been reported in patients with high-grade gliomas, meningiomas, brain metastases, pituitary adenomas, craniopharyngiomas, chordomas, and pinealomas.The applications of ICG have clearly expanded rapidly across different specialties since its initial development. As an NIR fluorophore, ICG has advantages over other FDA-approved fluorophores, all of which are currently in the visible-light spectrum, because of NIR fluorescence's increased tissue penetration and decreased autofluorescence. Recently, interest in the latest applications of ICG in brain tumor surgery has grown beyond its role as an NIR fluorophore, extending into shortwave infrared imaging and integration into nanotechnology. This review aims to summarize reported clinical studies on ICG fluorescence-guided surgery of intracranial tumors, as well as to provide an overview of the literature on emerging technologies related to the utility of ICG in neuro-oncological surgeries, including the following aspects: 1) ICG fluorescence in the NIR-II window; 2) ICG for photoacoustic imaging; and 3) ICG nanoparticles for combined diagnostic imaging and therapy (theranostic) applications.
Enantioselective Synthesis of Protected Isotetronic Acids (1998)

The first highly diastereo- and enantioselective synthesis of isotetronic acids (de, ee>98 %) is reported. Key steps in the reaction sequence are the diastereoselective aldol reaction of the 2-oxoester 1 (as the SAEP hydrazone) with aldehydes, followed by base-promoted lactonization to the corresponding hydrazonolactones. Subsequent oxidative cleavage of the hydrazone moiety afforded the enantiomerically pure O-protected isotetronic acids (R)-/(S)-2.
Mirror, Mirror on the Wall, 2014 Update: How the U.S. Health Care System Compares Internationally (2021)

The United States ranks last overall among 11 industrialized countries on measures of health system quality, efficiency, access to care, equity, and healthy lives, according to this Commonwealth Fund report, despite spending far more of its GDP on health.
Data services (2012)

Exploring the technology trends in basic, integrated, and cloud data services.
Design of a reversible inversed pH-responsive caged protein (2015)

Controlling the self-assembly behavior of caged proteins expands their potential applications in nanotechnology. While the structure of a caged E2 protein from pyruvate dehydrogenase is inert to any pH change, the incorporation of switchable GALA peptide that undergoes a coil-to-helix transition at acidic pH modulates its self-assembly property. By substituting the native α-helix at the C-terminus of the E2 protein with the GALA peptide, we report the first engineered caged protein with reversible inversed pH-responsive behavior. The redesigned caged E2 protein assumes an assembly profile that is distinct from the native state; it disassembles at pH 7.0 and self-assembles at pH 4.0 in a reversible manner. This unique reversible pH trigger suggests the applicability of the self-assembly control on other multi-subunit macromolecules.
Modelling of a magma energy geothermal power plant (1987)

We are currently investigating the engineering feasibility of drilling into an active magma body at a depth of roughly 5 km from the earth's surface, establishing a downhole heat exchange region, and extracting thermal energy from the magma body by circulating fluid through this heat exchange region. In the present paper, we evaluate the overall thermodynamic performance of various conceptual magma energy systems in which energy is added as heat to the fluid within the magma region and is converted to useful work in a power conversion cycle at the surface. Unusually high return temperatures and pressures may be available at the wellhead of such a circulating well. Cycles investigated here are an open Rankine power system in which steam from the magma well is circulated directly through a power conversion cycle and a closed Rankine cycle where the heated fluid from downhole is circulated through an aboveground heat exchanger to heat the cycle fluid. The downhole heat exchange region is established during the drilling process. As drilling proceeds into the magma, a solidified layer forms about the drilling tube due to heat exchange to the fluid. This solidified layer thermally fractures because of large temperature gradients between the cooled inner region and the heated outer region, thereby opening secondary flow paths. Two models of the downhole behavior have been used. In the simplest approach, denoted as the ''infinite area model,'' the water entering the pipe to return to the surface is assumed to be always at the temperature of the magma, independent of mass flow rate and other parameters. The other model is more detatiled and the fractured heat exchange region is modelled as a cylindrical porous layer through which fluid flows vertically. The net power and the performance aspects for the systems are investigated in terms of various parameters, including the characteristics of the downhole heat transfer.