gebhart/patrepeval huggingface dataset:
Primary Prevention of Atherosclerotic Cardiovascular Disease (2007)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Synthesis and application of heteroaromatic compounds with unusual structure and function. (1988)

This article describes the synthesis of novel derivatives of indigo and porphyrin, the structure and the function of which are of interest from photochemical and bioorganometallic points of view : (1) N-Substituted indigos undergo trans-cis isomerization and one- or two-electron reduction upon irradiation with visible light. The kinetic and thermodynamic profiles of these processes are greatly dependent on the nature of N-substituents. (2) Metal-carbon (or hydrogen) bond formation was demonstrated by using mono-, di-, and tri-valent rhodium porphyrins as mimics of reaction behaviors of Coenzyme B12. Novel organocobalt porphyrins such as π-complex, N, Co-bridged complex, and Cmeso, Co-bridged complex were obtained by the reactions of trivalent cobalt porphyrins with alkynes. (3) Organometallic porphyrins were converted into the N-substituted porphyrins which have recently turned out to be abnormal metabolites of cytochrome P 450, and into N (21), N (22) -bridged porphyrins which show interesting redox activities.
The Subclass Specificity for the Binding of Murine Myeloma Proteins to Macrophage and Lymphocyte Cell Lines and to Normal Spleen Cells (1978)

Abstract Murine myeloma proteins of the four IgG subclasses and of the IgA and IgM classes have been examined for their ability to inhibit the binding of affinity cross-linked trimeric rabbit IgG to various types of murine cells. In addition, proteins of the IgG1, IgG2a, and IgG2b subclasses have been cross-linked with dimethyl suberimidate and the purified oligomers have been tested for direct binding. With a macrophage line (P388D1), a lymphocyte line (AKTB-1), and normal spleen cells, proteins of the IgG1, IgG2a, and IgG2b subclasses all compete for binding at the same site. Differences in binding affinities between proteins of the IgG1, IgG2a, and IgG2b subclasses are small and are not greater than differences in affinities when proteins within a subclass are compared. Proteins of the IgG3 subclass and the IgM and IgA classes do not significantly inhibit IgG binding at the highest concentrations tested. P388D1 cells are also able to bind iodinated monomeric IgG2a proteins with higher affinity than expected from inhibition studies. This binding is inhibitable by proteins of the IgG1, 2a, and 2b subclasses, and is trypsin sensitive. These results could be explained by the existence of a second type of receptor, or by assuming that the iodination procedure increases the affinity of IgG2a proteins for P388D1 cells.
Arm coordination, power, and swim efficiency in national and regional front crawl swimmers (2010)

The effects of skill level on index of arm coordination (IdC), mechanical power output (P(d)), and swim efficiency were studied in front crawlers swimming at different speeds. Seven national and seven regional swimmers performed an arms-only intermittent graded speed test on the MAD-system and in a free condition. The MAD-system measured the drag (D) and P(d). Swimming speed (v), stroke rate (SR), stroke length (SL), stroke index (SI), relative entry, pull, push, and recovery phase durations, and IdC were calculated. Swim efficiency was assessed from SI, the coefficient of variation of calculated hip intra-cyclic velocity variations (IVV), and the efficiency of propulsion generation, i.e., the ratio of v(2) to tangential hand speed squared (u(2)). Both groups increased propulsive continuity (IdC) and hand speed (u) and applied greater P(d) to overcome active drag with speed increases (p<.05). This motor organization adaptation was adequate because SI, IVV, and v(2)/u(2) were unchanged. National swimmers appeared more efficient, with greater propulsive continuity (IdC) and P(d) to reach higher v than regional swimmers (p<.05). The regional swimmers exhibited a higher u and lower SI, IVV, and v(2)/u(2) compared to national swimmers (p<.05), which revealed lower effectiveness to generate propulsion, suggesting that technique is a major determinant of swimming performance.
Ocean Sequestration of Crop Residue Carbon: Recycling Fossil Fuel Carbon Back to Deep Sediments (2009)

For significant impact any method to remove CO2 from the atmosphere must process large amounts of carbon efficiently, be repeatable, sequester carbon for thousands of years, be practical, economical and be implemented soon. The only method that meets these criteria is removal of crop residues and burial in the deep ocean. We show here that this method is 92% efficient in sequestration of crop residue carbon while cellulosic ethanol production is only 32% and soil sequestration is about 14% efficient. Deep ocean sequestration can potentially capture 15% of the current global CO2 annual increase, returning that carbon backto deep sediments, confining the carbon for millennia, while using existing capital infrastructure and technology. Because of these clear advantages, we recommend enhanced research into permanent sequestration of crop residues in the deep ocean.
Use of Fourier series in the analysis of discontinuous periodic structures (1996)

The recent reformulation of the coupled-wave method by Lalanne and Morris [ J. Opt. Soc. Am. A13, 779 ( 1996)] and by Granet and Guizal [ J. Opt. Soc. Am. A13, 1019 ( 1996)], which dramatically improves the convergence of the method for metallic gratings in TM polarization, is given a firm mathematical foundation in this paper. The new formulation converges faster because it uniformly satisfies the boundary conditions in the grating region, whereas the old formulations do so only nonuniformly. Mathematical theorems that govern the factorization of the Fourier coefficients of products of functions having jump discontinuities are given. The results of this paper are applicable to any numerical work that requires the Fourier analysis of products of discontinuous periodic functions.
Closely Related Shrimp Species Identification by MALDI-ToF Mass Spectrometry (2009)

Tiger prawn, Penaeus monodon, and banana white prawn, Fenneropenaeus indicus—two of the most important commercial shrimp species—share world distribution, habitat, and similar morphometric characters. Because of commercial regulations about labeling and traceability requirements, species authentication methods are of great interest to fisheries and seafood industries. In this study, peptide mass fingerprints of both species are compared, using Matrix Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry (MALDI-TOF MS) after trypsin digestion of a protein resolved by two-dimensional gel electrophoresis. Though low variability among these species is observed, two peptides of mass 1077.6 and 1205.7 Da are found to be useful to differentiate them.
Platinum/silica sol-gel catalysts: effect of pH and platinum precursor (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPlatinum/silica sol-gel catalysts: effect of pH and platinum precursorT. Lopez, P. Bosch, M. Moran, and R. GomezCite this: J. Phys. Chem. 1993, 97, 8, 1671–1677Publication Date (Print):February 1, 1993Publication History Published online1 May 2002Published inissue 1 February 1993https://pubs.acs.org/doi/10.1021/j100110a033https://doi.org/10.1021/j100110a033research-articleACS PublicationsRequest reuse permissionsArticle Views416Altmetric-Citations33LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Reversible Covalent Patterning of Self-Assembled Monolayers on Gold and Silicon Oxide Surfaces (2005)

This paper describes the generation of reversible patterns of self-assembled monolayers (SAMs) on gold and silicon oxide surfaces via the formation of reversible covalent bonds. The reactions of (patterned) SAMs of 11-amino-1-undecanethiol (11-AUT) with propanal, pentanal, decanal, or terephthaldialdehyde result in dense imine monolayers. The regeneration of these imine monolayers to the 11-AUT monolayer is obtained by hydrolysis at pH 3. The (patterned) monolayers were characterized by Fourier transform infrared reflection absorption spectroscopy, X-ray photoelectron spectroscopy, contact angle and electrochemical measurements, and atomic force microscopy. Imines can also be formed by microcontact printing of amines on terephthaldialdehyde-terminated substrates. Lucifer Yellow ethylenediamine was employed as a fluorescent amine-containing marker to visualize the reversible covalent patterning on a terephthaldialdehyde-terminated glass surface by confocal microscopy. These experiments demonstrate that with reversible covalent chemistry it is possible to print and erase chemical patterns on surfaces repeatedly.
A Prospective Analysis of 100 Consecutive Lymphovenous Bypass Cases for Treatment of Extremity Lymphedema (2013)

Therapeutic, IV.
Improved deoxyribozymes for synthesis of covalently branched DNA and RNA (2010)

A covalently branched nucleic acid can be synthesized by joining the 2'-hydroxyl of the branch-site ribonucleotide of a DNA or RNA strand to the activated 5'-phosphorus of a separate DNA or RNA strand. We have previously used deoxyribozymes to synthesize several types of branched nucleic acids for experiments in biotechnology and biochemistry. Here, we report in vitro selection experiments to identify improved deoxyribozymes for synthesis of branched DNA and RNA. Each of the new deoxyribozymes requires Mn²(+) as a cofactor, rather than Mg²(+) as used by our previous branch-forming deoxyribozymes, and each has an initially random region of 40 rather than 22 or fewer combined nucleotides. The deoxyribozymes all function by forming a three-helix-junction (3HJ) complex with their two oligonucleotide substrates. For synthesis of branched DNA, the best new deoxyribozyme, 8LV13, has k(obs) on the order of 0.1 min⁻¹, which is about two orders of magnitude faster than our previously identified 15HA9 deoxyribozyme. 8LV13 also functions at closer-to-neutral pH than does 15HA9 (pH 7.5 versus 9.0) and has useful tolerance for many DNA substrate sequences. For synthesis of branched RNA, two new deoxyribozymes, 8LX1 and 8LX6, were identified with broad sequence tolerances and substantial activity at pH 7.5, versus pH 9.0 for many of our previous deoxyribozymes that form branched RNA. These experiments provide new, and in key aspects improved, practical catalysts for preparation of synthetic branched DNA and RNA.
Disturbance, age and size structure in stands of Pinus uncinata Ram (1992)

[es] Las estructuras de tamaño y edad de dos bosques monoespecificos subalpinos de Pinus uncinata en el Pirineo, fueron estudiadas e interpretadas introduciendo una clasificación sencilla de los árboles según la exposición de su copa a la radiación solar directa. Ambas poblaciones muestran distribuciones de diámetro de J invertida irregulares, cuya Interpretación es incierta. Por el contrario, la estructura de edad en ambos bosques muestra picos visibles, los cuales, si se tienen en cuenta la exposición de la copa, indican que la regeneración se produce en claros del bosque. Se analizaron las series de anillos de crecimiento de los árboles de cada sitio para reconstruir su historia reciente de perturbaciones Identificando los incrementos bruscos del crecimiento. El régimen de perturbaciones en los dos bosques es diferente, y en ambos casos muestra un efecto madelador análogo sobre la estructura de edad. Se concluye que P. uncinata se comporta como una especie heliófila que puede formar bosques maduros o multicohorte bajo determinados regímenes de perturbaciones suaves, gracias a su capacidad para iniciar la regeneración en claros pequeños. Este proceso tiene lugar en un lapso de tiempo corto después de la incidencia de las perturbaciones. [fr] Les structures de taille et d'âge de deux forêts monospécifiques subalpines de Pinus uncinata, dans les Pyrénées, ont été étudiées et interprétées en introduisant un classement simple des arbres selon l'exposition du houppier à la radiation solaire directe. Ces deux peuplements ont montré des distributions irrégulières du diamètre en J Inversé, dont l'interprétation est incertaine. Au contraire, la structure d'âge chez les deux forêts montre des pics visibles qui, si l'on tient compte de l'exposition du houppier, indiquent que la régénération a lieu dans les clairières de la forêt. On a analysé les séries d'anneaux de croissance des arbres de chaque lieu afin de reconstruire l'histoire récente de leurs perturbations en identifiant les augmentations brusques de croissance. Le régime de perturbations des deux forêts était différent, et dans les deux cas on voyait un effet analogue de configuration en ce qui concerne la structure d'âge. On en a conclu que P. uncinata se comporte en tant qu'espèce héliophile pouvant former des forêts adultes on multicohorte sous des régimes donnés de légères perturbations, grâce à sa capacité pour entamer la régénération dans de petites clairières. Ce processus se déroule peu de temps après l'incidence des perturbations.
The Predictive Power of Synthetic Nucleic Acid Technologies in RNA Biology (2014)

CONSPECTUS: The impact of nucleic acid nanotechnology in terms of transforming motifs from biology in synthetic and translational ways is widely appreciated. But it is also emerging that the thinking and vision behind nucleic acids as construction material has broader implications, not just in nanotechnology or even synthetic biology, but can feed back into our understanding of biology itself. Physicists have treated nucleic acids as polymers and connected physical principles to biology by abstracting out the molecular interactions. In contrast, biologists delineate molecular players and pathways related to nucleic acids and how they may be networked. But in vitro nucleic acid nanotechnology has provided a valuable framework for nucleic acids by connecting its biomolecular interactions with its materials properties and thereby superarchitecture ultramanipulation that on multiple occasions has pre-empted the elucidation of how living cells themselves are exploiting these same structural concepts. This Account seeks to showcase the larger implications of certain architectural principles that have arisen from the field of structural DNA/RNA nanotechnology in biology. Here we draw connections between these principles and particular molecular phenomena within living systems that have fed in to our understanding of how the cell uses nucleic acids as construction material to achieve different functions. We illustrate this by considering a few exciting and emerging examples in biology in the context of both switchable systems and scaffolding type systems. Due to the scope of this Account, we will focus our discussion on examples of the RNA scaffold as summarized. In the context of switchable RNA architectures, the synthetic demonstration of small molecules blocking RNA translation preceded the discovery of riboswitches. In another example, it was after the description of aptazymes that the first allosteric ribozyme, glmS, was discovered. In the context of RNA architectures as structural scaffolds, there are clear parallels between DNA origami and the recently emerging molecular mechanism of heterochromatin formation by Xist RNA. Further, following the construction of well-defined 2D DNA-protein architectures, the striking observation of remarkably sculpted 2D RNA-protein hydrogel sheets in Caenorhabditis elegans speaks to the in vivo relevance of designer nucleic acid architectures. It is noteworthy that discoveries of properties in synthetic space seem to precede the uncovering of similar phenomena in vivo.
Geosmin and Musty-Muddy Flavors in Pond-Raised Channel Catfish (1986)

Monthly sensory (taste) analyses of channel catfish Ictalurus punctatus from 11 commercial culture ponds in Alabama during April-October 1983 showed that earthy-musty flavor was the major off-flavor during the summer growing season. Geosmin (1,10-trans-dimethyl-trans-(9)-decalol) was found by gas chromatography in detectable amounts, 3.7 to over 200 μg/kg of fish flesh, in 80% of fish having earthy-musty or detritus (pond mud) flavor. Geosmin was not found in fish without these flavors. The geosmin analysis procedure used in this study recovered 68 to 85% of geosmin added to fish flesh, at concentrations ranging from 8 to 32 μg/kg, with relatively high consistency (SD = 2.5–3.3). Reproducibility in analysis of fish with naturally occurring geosmin (6–15 μg/kg fish) was also favorable (coefficients of variation, 100˙SD/mean, 6.9–16.8%). The compound 2-methylisoborneol, found in muddy-flavored rainbow trout Salmo gairdneri, could not be confirmed as an off-flavor compound in channel catfish. The use of geosmin analysis to partially replace sensory evaluation of channel catfish for off-flavor during summer appears feasible.
Landscape and Seascape Climate Change Planning and Action (2012)

As discussed in chapter 1 , revisiting our conservation goals and actions in light of climate change does not mean that we must discard what we have learned about critical conservation tools and strategies. We do, however, need to explicitly consider future climate change as we make conservation investments. Although climate change will not always be the most urgent problem facing biodiversity conservation, it will increasingly constitute a lens through which we must examine our actions. By anticipating the direct and indirect consequences of different scenarios of climate change for the particular species, ecosystems, and natural processes we aim to protect—and then determining appropriate and necessary conservation actions in light of those changes—we increase the likelihood of making informed decisions about both near- and long-term threats that will improve our ability to achieve conservation success.
Group-Delay Engineered Noncommensurate Transmission Line All-Pass Network for Analog Signal Processing (2010)

A group-delay engineered noncommensurate transmission line two-port all-pass network for analog signal-processing applications is presented, analytically modeled, and experimentally demonstrated. This network consists of transversally cascaded C-sections, which are distributed implementations of the bridged-T equalizer lumped circuit. It is obtained by interconnecting the alternate ports of adjacent lines of a 2 <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">N</i> -port coupled transmission line network with transmission line sections, and it is modeled using multiconductor transmission line theory with per-unit-length capacitance matrix <b xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">C</b> and inductance matrix <b xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">L</b> . By allowing the different C-sections of the network to exhibit different lengths, a generalized group-delay engineering procedure is proposed, where quasi-arbitrary group-delay responses are achieved by combining the group-delay responses of C-sections with different lengths. A computer design approach based on genetic algorithms is applied for synthesis, which consists of determining the structural parameters of the different C-section groups. Using this approach, noncommensurate networks are group-delay engineered in edge-coupled stripline technology, and Gaussian, linear and quadratic group-delay responses are realized. The theoretical results are validated by experiment. Finally, two application examples of analog signal processing-a tunable impulse delay line and a real-time frequency discriminator-using the proposed dispersive noncommensurate all-pass networks are presented.
Modeling of a Functional Surface using a Modified B-spline (2005)

This research presents modeling of a functional surface that is constructed with a free-formed surface. The modeling of functional surfaces, being introduced in this paper, adopts a modified B-spline that utilizes an approximating technique. The modified B-Spline is constructed with altered control vertices. It is applied to measure the surface of an impeller blade. This research builds an algorithm accepting inputs of measured points. Generating the cutter-paths for NC machining employs the model of the constructed surfaces. The machined surfaces that are generated in several cases are compared with each other in the aspect of machining accuracy.
Robust anion conductive polymers containing perfluoroalkylene and pendant ammonium groups for high performance fuel cells (2017)

Well-designed ammonium-functionalized polymers achieved high performance and durability in hydrazine alkaline fuel cells.
AN X-RAY DIFFRACTION STUDY OF PMN-PT CERAMICS NEAR THE MORPHOTROPIC PHASE BOUNDARY (2002)

The temperature dependence of crystal structures and lattice parameters has been determined for compositions of x = 0.20, 0.30 and 0.35 in the system (1-x)PMN-xPT, which has shown great potential for sonar sensor applications. The temperatures of the onset of the cubic-pseudocubic transformation in x = 0.20, and of the cubic-tetragonal transformations in x = 0.30 and 0.35, have been established from studies of diffraction profiles and confirmed from lattice parameter-temperature plots. As these phase changes transform progressively over ranges of temperature, the phase boundaries normally inserted in diagrams for the system should be shown as two phase regions, rather than narrow lines. On the basis of these results, the dielectric state diagrams of the PMN-PT system have been modified to produce a partial realization diagram that includes the start temperatures of the various phase transformations.