gebhart/patrepeval huggingface dataset:
Description and clinical evaluation of a new computerized periodontal probe‐the Florida Probe (1988)

A new periodontal probing system has been developed which incorporates the advantages of constant probing force, precise electronic measurement to 0.1 mm and computer storage of the data. The system includes a probe handpiece, displacement transducer with digital readout, foot switch, computer interface and personal computer. A unique movable arm design enables the probe handpiece to maintain smooth operation and makes it easy to clean and sterilize. Electronic recording of the data (actuated by pressing a foot switch) eliminates errors which occur when probe tip markings are read visually and the data are called to an assistant. Computer storage and analysis of the data facilitates detecting changes in pocket depth and attachment level by rapidly comparing data recorded at different visits. The system was evaluated in 3 experiments using a 0.4 mm diameter tip and a 25 g probing force. The standard deviation of repeated pocket depth measurement was less (0.58 mm versus 0.82 mm) than that of a common probe. With paired readings referenced to an occlusal stent, the standard deviation of repeated attachment level measurements was 0.28 mm. A loss of attachment level was detected to a certainty of 99% with less than a 1 mm change. This is a significant improvement over common probes, which require a 2-3 mm change for equivalent positive identification of change in attachment level.
Atrial conduction disturbance as an indicator of rejection after cardiac transplantation. (2000)

Abnormalities of the terminal force of the P wave in Lead V1 (ptf-V1) and dispersion of corrected atrial repolarization (Ta-TcD) are believed to represent interatrial conduction defect.To determine whether atrial conduction disturbance correlates with cardiac allograft rejection, we analyzed 249 twelve-lead-electrocardiograms, echocardiograms, hemodynamic parameters, and endomyocardial biopsys from 137 patients with heart transplantation. Both ptf-V1 and Ta-TcD were significantly increased in patients with severe, moderate, and mild rejection. In 22 patients, significant increases of the ptf-V1 and Ta-TcD were observed before positive histological findings, and significantly correlated with severity of rejection during 5- week to 1-year follow-up. Increase of 0.030 mm x sec in ptf-V1 or 0.040 s1/2 in Ta-TcD indicated cardiac rejection > or =1B with sensitivity of 88 and 83%, specificity of 85 and 77%, respectively.These results suggest that the ptf-V1 and Ta-TcD might be an adjunct to detect rejection and reduce the number of surveillance EMB.
Optical fiber humidity sensor based on evanescent-wave scattering (2004)

The phenomenon of evanescent-wave scattering (EWS) is used to design an optical-fiber humidity sensor. Porous solgel silica (PSGS) coated on the surface of a silica optical-fiber core scatters evanescent waves that penetrate the coating layer. Water molecules in the gas phase surrounding the optical fiber can be absorbed into the inner surface of the pores of the porous silica. The absorbed water molecules form a thin layer of liquid water on the inner surface of the porous silica and enhance the EWS. The amount of water absorbed into the PSGS coating is in dynamic equilibrium with the water-vapor pressure in the gas phase. Therefore the humidity in the air can be quantitatively determined with fiber-optic EWS caused by the PSGS coating. The humidity sensor reported here is fast in response, reversible, and has a wide dynamic range. The possible interference caused by EWS to an optical-fiber gas sensor with a reagent-doped PSGS coating as a transducer is also discussed.
Very large magnetoresistance in perovskite-like La-Ca-Mn-O thin films (1994)

Colossal magnetoresistance with more than a thousandfold change in resistivity (ΔR/RH=127 000% at 77 K, H=6 T) has been obtained in epitaxially grown La-Ca-Mn-O thin films. This magnetoresistance value is about three orders of magnitude higher than is typically seen in the giant-magnetoresistance-type metallic, superlattice films. The temperature of peak magnetoresistance is located in the region of metallic resistivity behavior. As the magnetoresistance peak occurs not at the temperature of magnetic transition but at a temperature where the magnetization is still substantial, the spin-disorder scattering is not likely to be the main mechanism in these highly magnetoresistive films. The peak can be shifted to near room temperature by adjusting processing parameters. Near-room-temperature ΔR/RH values of ∼1300% at 260 K and ∼400% at 280 K have been observed. The presence of grain boundaries appears to be very detrimental to achieving large magnetoresistance in the lanthanum manganite compounds. The fact that the electrical resistivity of a material can be manipulated by magnetic field to change by orders of magnitude could be useful for various device applications.
More About Hazard-Response Robot For Combustible Atmospheres (1995)

Report presents additional information about design and capabilities of mobile hazard-response robot called Hazbot III. Designed to operate safely in combustible and/or toxic atmosphere. Includes cameras and chemical sensors helping human technicians determine location and nature of hazard so human emergency team can decide how to eliminate hazard without approaching themselves.
Towards an in vivo wireless mobile robot for surgical assistance. (2008)

The use of miniature in vivo robots that fit entirely inside the peritoneal cavity represents a novel approach to laparoscopic surgery. Previous work has demonstrated that mobile and fixed-base in vivo robots can be used to improve visualization of the surgical field and perform surgical tasks such as collecting biopsy tissue samples. All of these robots used tethers to provide for power and data transmission. This paper describes recent work focused on developing a modular wireless mobile platform that could be used for in vivo robotic sensing and manipulation applications. One vision for these types of self-contained in vivo robotic devices is that they could be easily carried and deployed by non-medical personnel at the site of an injury. Such wireless in vivo robots are much more transportable and lower cost than current robotic surgical assistants, and could ultimately allow a surgeon to become a remote first responder irrespective of the location of the patient.
Dual-band frequency selective surfaces with higher-order band-pass responses (2010)

In this paper, a new technique for designing low-profile dual-band frequency selective surfaces, with second-order band pass responses, is presented. Using this technique, a dual-band response with a small separation between the two bands and high out-of-band rejection can be achieved. Similar to the structure reported in [6], the constituting elements composed of resonant elements and sub-wave length non-resonant elements. The combination of sub-wavelength unit cell dimensions and the small overall thickness of the proposed structure results in an FSS with a frequency response that is less sensitive to the angle of incidence of the EM wave.
HIGH-POWER OPTICAL SOURCE USING DYE-DOPED POLYMER OPTICAL FIBER (1996)

Basic characteristics of organic-dye doped polymer optical fibers (DPOFs) are demonstrated. The devices contain laser dye, such as Rhodamine 6G (R6G) and Rhodamine B (RB) in the core region. Firstly, amplification characteristics of DPOF amplifiers (PO-FAs) excited by a pulse-operated, doubled Nd:YAG laser are demonstrated, e.g., a 250 mm-length of RB-POFA gives 1 kW (30 dB) of amplified signal at 591 nm. Next, an all solid state system of RB DPOF laser (POFL) is discussed by numerical simulation and the experimental result of high-power amplified spontaneous emission (ASE) by strong excitation of DPOF is shown.
Abstract 1885: Potent tumoricidal activity of a FGFR4 CART in rhabdomyosarcoma (2021)

Abstract Despite decades of multi-module therapies, RMS remains incurable once it has metastasized, thus new therapeutic strategies are warranted. FGFR4 is a developmentally regulated cell surface receptor tyrosine kinase, overexpressed in virtually all, mutationally activated in about 10% of RMS, and directly activated by PAX3-FOXO1 fusion protein which makes it a tractable target for immunotherapy. We generated fifteen binders against FGFR4 and characterized them further as candidate molecules for immune therapy. We found that 3A11, a mouse IgG antibody, bound to FGFR4 positive cell lines. The VL and VH domain of 3A11 was cloned and made into scFvFc format (mouse Fv and Human IgG1 Fc). The chimeric form of 3A11 antibody was successfully produced in vitro and retained its FGFR4 specificity with an observed binding affinity at nanomolar range. By ELISA using the extra cellular domain of human FGFR1, FGFR2, FGFR3 or FGFR4, 3A11 scFvFc showed dose dependent binding to FGFR4 only. We then made 3A11 into a second generation CAR. Human T cells transduced with 3A11 CAR construct were found to be highly potent at inducing IFN-γ, TNF-α, IL-2 and cytotoxicity when the FGFR4-CART was co-cultured with RMS cells, but not with RMS cells with FGFR4 knocked out and FGFR4 negative cells. Our in vivo testing also found that 3A11 CART was able to eliminate RMS cells in murine xenograft metastatic models. Here we report the successful generation of binders specific to human FGFR4. FGFR4 CAR developed from 3A11 was able to kill FGFR4 positive target cells both in-vivo and in-vitro. Thus, 3A11 CAR T cells targeting FGFR4 may provide effective immune therapies for rhabdomyosarcoma and other FGFR4 expressing cancers and clinical trials are planned. Citation Format: Adam Cheuk, Meijie Tian, Jeetendra Kumar, Peter Azorsa, Nityashree Shivaprasad, Dina Schneider, Berkley Gryder, Jun Wei, Young Song, Xinyu Wen, Sivasish Sindiri, Joon-Yong Chung, Zhongyu Zhu, Dimiter Dimitrov, Stephen Hewitt, Boro Dropulic, Rimas Orentas, Javed Khan. Potent tumoricidal activity of a FGFR4 CART in rhabdomyosarcoma [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2021; 2021 Apr 10-15 and May 17-21. Philadelphia (PA): AACR; Cancer Res 2021;81(13_Suppl):Abstract nr 1885.
RTL-PSC: Automated Power Side-Channel Leakage Assessment at Register-Transfer Level (2019)

Power side-channel attacks (SCAs) have become a major concern to the security community due to their noninvasive feature, low-cost, and effectiveness in extracting secret information from hardware implementation of cryto algorithms. Therefore, it is imperative to evaluate if the hardware is vulnerable to SCAs during its design and validation stages. Currently, however, there is little known effort in evaluating the vulnerability of a hardware to SCAs at early design stage. In this paper, we propose, for the first time, an automated framework, named RTL-PSC, for power side-channel leakage assessment of hardware crypto designs at register-transfer level (RTL) with built-in evaluation metrics. RTL-PSC first estimates power profile of a hardware design using functional simulation at RTL. Then it utilizes the evaluation metrics, comprising of KL divergence metric and the success rate (SR) metric based on maximum likelihood estimation to perform power side-channel leakage (PSC) vulnerability assessment at RTL. We analyze Galois-Field (GF) and Look-up Table (LUT) based AES designs using RTL-PSC and validate its effectiveness and accuracy through both gate-level simulation and FPGA results. RTL-PSC is also capable of identifying blocks* inside the design that contribute the most to the PSC vulnerability which can be used for efficient countermeasure implementation.
Thin magnetic conductor substrate for placement-immune, electrically-small antennas. (2011)

An antenna is considered to be placement-immune when the antenna operates effectively regardless of where it is placed. By building antennas on magnetic conductor materials, the radiated fields will be positively reinforced in the desired radiation direction instead of being negatively affected by the environment. Although this idea has been discussed thoroughly in theoretical research, the difficulty in building thin magnetic conductor materials necessary for in-phase field reflections prevents this technology from becoming more widespread. This project's purpose is to build and measure an electrically-small antenna on a new type of non-metallic, thin magnetic conductor. This problem has not been previously addressed because non-metallic, thin magnetic conductor materials have not yet been discovered. This work proposed the creation of an artificial magnetic conductor (AMC) with in-phase field reflections without using internal electric conductors, the placement of an electrically-small antenna on this magnetic conductor, and the development of a transmit-receive system that utilizes the substrate and electrically-small antenna. By not using internal electric conductors to create the AMC, the substrate thickness can be minimized. The electrically-small antenna will demonstrate the substrate's ability to make an antenna placement immune, and the transmit-receive system combines both the antenna and the substrate while adding a third layer of system complexity to demonstrate the complete idea.
Clinically deployable Kinesia™ technology for automated tremor assessment (2009)

The objective was to design, build, and assess Kinesia, a wireless system for automated assessment of Parkinson's disease (PD) tremor. The current standard in evaluating PD is the Unified Parkinson's Disease Rating Scale (UPDRS), a qualitative ranking system typically completed during an office visit. Kinesia integrates accelerometers and gyroscopes in a compact patient-worn unit to capture kinematic movement disorder features. Objectively quantifying PD manifestations with increased time resolution should aid in evaluating efficacy of treatment protocols and improve patient management. In this study, PD subjects performed the tremor subset of the UPDRS motor section while wearing Kinesia. Quantitative kinematic features were processed and highly correlated to clinician scores for rest tremor (r(2) = 0.89), postural tremor (r(2) = 0.90), and kinetic tremor (r(2) = 0.69). The quantitative features were used to develop a mathematical model that predicted tremor severity scores for new data with low errors. Finally, PD subjects indicated high clinical acceptance.
SOI bonded wafer process for high precision MEMS inertial sensors (2005)

A process for fabricating MEMS devices using a silicon on insulator (SOI) wafer bonded to a substrate glass or silicon wafer is presented. In this process, the device layer of the SOI wafer is bonded to the substrate wafer, and the handle and SiO2 layers of the SOI wafer are subsequently removed. This method of manufacturing MEMS devices using SOI wafers offers important advantages over alternative SOI wafer processes, and is being implemented to manufacture high accuracy MEMS inertial devices.
Delay-Encoded Harmonic Imaging (DE-HI) in Multiplane-Wave Compounding (2016)

The development of ultrafast ultrasound imaging brings great opportunities to improve imaging technologies such as shear wave elastography and ultrafast Doppler imaging. In ultrafast imaging, several tilted plane or diverging wave images are coherently combined to form a compounded image, leading to trade-offs among image signal-to-noise ratio (SNR), resolution, and post-compounded frame rate. Multiplane wave (MW) imaging is proposed to solve this trade-off by encoding multiple plane waves with Hadamard matrix during one transmission event (i.e. pulse-echo event), to improve image SNR without sacrificing the resolution or frame rate. However, it suffers from stronger reverberation artifacts in B-mode images compared to standard plane wave compounding due to longer transmitted pulses. If harmonic imaging can be combined with MW imaging, the reverberation artifacts and other clutter noises such as sidelobes and multipath scattering clutters should be suppressed. The challenge, however, is that the Hadamard codes used in MW imaging cannot encode the 2<sup>nd</sup> harmonic component by inversing the pulse polarity. In this paper, we propose a delay-encoded harmonic imaging (DE-HI) technique to encode the 2<sup>nd</sup> harmonic with a one quarter period delay calculated at the transmit center frequency, rather than reversing the pulse polarity during multiplane wave emissions. Received DE-HI signals can then be decoded in the frequency domain to recover the signals as in single plane wave emissions, but mainly with improved SNR at the 2<sup>nd</sup> harmonic component instead of the fundamental component. DE-HI was tested experimentally with a point target, a B-mode imaging phantom, and in-vivo human liver imaging. Improvements in image contrast-to-noise ratio (CNR), spatial resolution, and lesion-signal-to-noise ratio ( l SNR) have been achieved compared to standard plane wave compounding, MW imaging, and standard harmonic imaging (maximal improvement of 116% on CNR and 115% on l SNR as compared to standard HI around 55 mm depth in the B-mode imaging phantom study). The potential high frame rate and the stability of encoding and decoding processes of DE-HI were also demonstrated, which made DE-HI promising for a wide spectrum of imaging applications.
Regeneration of Lactic and Succinic Acid-Laden Basic Sorbents by Leaching with a Volatile Base in an Organic Solvent (1998)

Leaching with an organic solution of a volatile base was explored as a method of regenerating tertiary amine and pyridyl sorbents. Experimental data are presented that show that regeneration efficiency correlates with the nonaqueous basicity of the regenerant as measured by the Gutmann donicity scale. Essentially complete regeneration of lactic acid-laden Dowex MWA-1 was achieved when 8−10 mol of trimethylamine were present for every mole of adsorbed acid; adequate (>70%) regeneration was obtained at a 2:1 molar ratio. The resulting trimethylamine−lactic acid complex can be thermally decomposed fully when trimethylamine is employed in an organic solvent instead of in water. A likely cause of the incomplete thermal decomposition of trimethylammonium lactate in previous, water-based systems is the aqueous environment in which the decomposition was performed.
Analysis of application performance and its change via representative application signatures (2008)

Application servers are a core component of a multitier architecture that has become the industry standard for building scalable client-server applications. A client communicates with a service deployed as a multi-tier application via request-reply transactions. A typical server reply consists of the web page dynamically generated by the application server. The application server may issue multiple database calls while preparing the reply. Understanding the cascading effects of the various tasks that are sprung by a single request-reply transaction is a challenging task. Furthermore, significantly shortened time between new software releases further exacerbates the problem of thoroughly evaluating the performance of an updated application. We address the problem of efficiently diagnosing essential performance changes in application behavior in order to provide timely feedback to application designers and service providers. In this work, we propose a new approach based on an application signature that enables a quick performance comparison of the new application signature against the old one, while the application continues its execution in the production environment. The application signature is built based on new concepts that are introduced here, namely the transaction latency profiles and transaction signatures. These become instrumental for creating an application signature that accurately reflects important performance characteristics. We show that such an application signature is representative and stable under different workload characteristics. We also show that application signatures are robust as they effectively capture changes in transaction times that result from software updates. Application signatures provide a simple and powerful solution that can further be used for efficient capacity planning, anomaly detection, and provisioning of multi-tier applications in rapidly evolving IT environments.
Improved quantum ternary arithmetic (2016)

Qutrit (or ternary) structures arise naturally in many quantum systems, notably in certain non-abelian anyon systems. We present efficient circuits for ternary reversible and quantum arithmetics. Our main result is the derivation of circuits for two families of ternary quantum adders. The main distinction from the binary adders is a richer ternary carry which leads potentially to higher resource counts in universal ternary bases. Our ternary ripple adder circuit has a circuit depth of O(n) and uses only 1 ancilla, making it more efficient in both, circuit depth and width, when compared with previous constructions. Our ternary carry lookahead circuit has a circuit depth of only O(log n), while using O(n) ancillas. Our approach works on two levels of abstraction: at the first level, descriptions of arithmetic circuits are given in terms of gates sequences that use various types of non-Clifford reflections. At the second level, we break down these reflections further by deriving them either from the two-qutrit Clifford gates and the non-Clifford gate C(X) : |i, ji 7→ |i, j + δi,2 mod 3i or from the two-qutrit Clifford gates and the non-Clifford gate P9 = diag(e −2π i/9 , 1, e 2π i/9 ). The two choices of elementary gate sets correspond to two possible mappings onto two different prospective quantum computing architectures which we call the metaplectic and the supermetaplectic basis, respectively. Finally, we develop a method to factor diagonal unitaries using multi-variate polynomials over the ternary finite field which allows to characterize classes of gates that can be implemented exactly over the supermetaplectic basis.
Agroinoculation: A Simple Procedure for Systemic Infection of Plants with Viruses (2008)

Plant-virus interaction studies, for long, plagued by asynchronous/failed infections, have improved since the usage of Agrobacterium as a delivery agent for viral genomes. Popularly known as "agroinoculation," this method has revolutionized plant virology studies, leading to identification of viruses as casual agents of disease, viral genome mutagenesis and recombination analyses, and virus-induced gene silencing (VIGS) applications. We present here a brief overview of the recent applications of this method and a detailed protocol for agroinoculation and VIGS used in our laboratory.
Graphene-carbon nanotube hybrid transparent conductive films (2013)

Graphene films grown by chemical vapor deposition of hydrocarbon gases on metal surfaces have been integrated with single-walled carbon nanotube (SWNT) films. Using simple thin film fabrication methods and the sequential deposition of these two components we obtained graphene/SWNT hybrid films with good structural quality. Obtained graphene/SWNT films possess opto-electrical properties better than that of pure graphene or SWNT films, making them promising for transparent conductive film (TCF) applications. The hybrid films have been tested as a transparent electrode in electrochromic (EC) devices to replace indium tin oxide (ITO) TCFs.