gebhart/patrepeval huggingface dataset:
Egészségügyi szakdolgozók COVID-19 elleni védőoltással kapcsolatos vélekedései a koronavírus pandémia idején (2022)

A vizsgálat célja volt felmérni, hogy az egészségügyi szakdolgozók miként reagáltak a Covid-19-vakcinákra, mennyire voltak elfogadók vele. Az elfogadás mértékét összevetettük különböző szociodemográfiai és munkahelyi tényezőkkel, valamint a kiégéssel és a depresszióval. A keresztmetszeti vizsgálat egy saját szerkesztésű online kérdőívvel történt 2022.01.27.–2022.02.14. között. Az adatokat leíró statisztikával, valamint χ2-, és Kruskal–Wallis-próbákkal elemeztük (p<0,05). A 10 285 válaszadó 57,8%-a biztonságosnak tartja a Covid-19 elleni védőoltásokat. Az idősebb életkor, a férfi nem, házasság és özvegység, a magasabb iskolai végzettség, a Covid-ellátásban végzett munka, az egészségügyben eltöltött évek száma, az alapellátásban végzett munka növeli a védőoltás elfogadását. A rossz lelkiállapot együtt jár a védőoltáshoz való negatív hozzáállással. Megállapíthatjuk, hogy az egészségügyi szakdolgozók körében inkább a Covid-19-fertőzés elleni védőoltás elfogadása jellemző, azonban a depresszió és a kiégés magas szintje együtt jár a védőoltásról alkotott negatív véleménnyel, az oltás elutasításával.
Advances in Evaluating the Oral Bioavailability of Inorganics in Soil for Use in Human Health Risk Assessment (1999)

Cleanup goals for sites affected by inorganic contaminants often are established on the basis of risk assessments, and these assessments rely on the estimated oral toxicity of the substances of concern. These toxicity estimates typically are based on historical studies in which a soluble salt of the metal was dissolved in water or mixed in food and then ingested by an animal or human. However, these toxicity studies do not account for the characteristics of a metal in soil or the limitations that these characteristics place on enteric absorption of that metal. Therefore, a more accurate risk assessment must account for the bioavailability of the metal in site-specific soil, relative to the bioavailability of the metal in the form administered in the toxicity study (i.e., the relative bioavailability of the element in soil). Historically, relative bioavailability estimates for metals in soil have been based on in vivo studies in laboratory animals. Given the costs and time constraints associated with such studies, it is clear that a more efficient alternative is desirable. The most promising option involves the development and validation of in vitro extraction tests that are predictive of oral metals bioavailability from soil. Such tests would provide a rapid and inexpensive method for developing more accurate exposure estimates for use in human health risk assessments. This paper reviews the site-specific in vivo studies that have been conducted to estimate the relative bioavailability of arsenic and lead in soil, discusses the soil and mineralogical factors that influence the bioavailability of these elements, and reviews the research to date on the development of bioavailability-predictive extraction tests for metals in soil. Finally, this paper outlines an ongoing collaborative research project to formally validate an in vitro extraction test for use in estimating the oral bioavailability of arsenic and lead in soil.
Kinetics of isomerization of maleic acid using ammonium bromide and ammonium peroxydisulfate as catalyst (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTKinetics of isomerization of maleic acid using ammonium bromide and ammonium peroxydisulfate as catalystJuan R. Gonzalez-Velasco, Jose A. Gonzalez-Marcos, Miguel A. Gutierrez-Ortiz, and Jose I. Gutierrez-OrtizCite this: Ind. Eng. Chem. Res. 1991, 30, 9, 2138–2143Publication Date (Print):September 1, 1991Publication History Published online1 May 2002Published inissue 1 September 1991https://pubs.acs.org/doi/10.1021/ie00057a012https://doi.org/10.1021/ie00057a012research-articleACS PublicationsRequest reuse permissionsArticle Views231Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Stress‐Induced Void Formation in Interlevel Polysilicon Films during Polybuffered Local Oxidation of Silicon (1993)

During polybuffered local oxidation of silicon processing the formation of pits in the polysilicon buffer layer is often observed after wet nitride etch. While nitridation of whole polysilicon grains due to a chemical reaction of ammonia, water, and silicon is discussed in the literature, it is shown in this work that the pits originate from voids in the polysilicon film which are already created during oxidation. For the first time, a stress‐induced migration effect in polysilicon, analogous to void formation in narrow aluminum interconnect lines, is proposed as the primary cause of the pit problem. Based on the experimental findings a process strategy is suggested to avoid substrate damage in the active transistor area.
Structure, expression and gene sequence of a juvenile hormone esterase-related protein from metamorphosing larvae of <i>Trichoplusia ni</i> (1994)

A carboxylesterase with an encoded molecular size of 61 kDa and a high sequence similarity to juvenile hormone esterase (JHE) has been cloned from cDNA prepared from final instar larvae of Trichoplusia ni. The absence of a recognizable encoded signal peptide suggests that the enzyme, JHER (for JHE-related) may not be secreted, in contrast to JHE. When the amino acid sequence of JHE, JHER and other esterases were mapped onto the secondary and tertiary structure determined crystallographically for acetylcholinesterase, certain structural features for the substrate binding/catalytic site were identified as common only to JHE and JHER. However, several differences between JHE and JHER were identified in residues at the binding/catalytic site, suggesting that although the two enzymes prefer similar natural substrates, these substrates are not identical. JHER is present as a single-copy gene, transcribed during the feeding stage of the final stage of the final larval stadium, but not after metamorphic commitment to the pupal developmental programme. The gene transcribes a single-size message of 2.0 kb. The genes for JHER and JHE appear to be physically juxtaposed in the T. ni genome. The 5' flanking sequence to the JHER gene possesses some sequences in common with the JHE gene, but is also missing some regulatory elements previously identified in the JHE gene. Sequences conserved between the promoters for the two genes were identified that were different from previously reported regulatory elements of eukaryotic transcription factors.
O PSICÓLOGO E O PACIENTE NO ESTÁGIO DE FIM DE VIDA HOSPITALIZADO: uma discussão sobre o medo da morte (2018)

O presente artigo traz esclarecimentos sobre a saude mental do paciente no estagio de fim de vida ante a morte iminente, com o intuito de auxiliar os profissionais da area da Psicologia no exercicio de sua profissao mediante a situacoes conflitantes com o tema abordado. Portanto, tem como objetivo compreender o significado de morte conforme tres abordagens psicologicas, discorrendo sobre o medo da morte no âmbito hospitalar e o trabalho do psicologo frente a situacoes vivenciadas pelo paciente hospitalizado em fase de fim de vida. Atraves de uma pesquisa bibliografica e sistematica, baseada em autores como Sartre (2002), Freud (1920) e Oliveira (2009), o presente estudo propoe uma discussao sobre o medo da morte experimentado pelo paciente no estagio de fim de vida e o tratamento psicologico oferecido a esse paciente nessas circunstâncias. Auxiliar a aceitacao da morte e o sentido desta para aquele paciente e essencial, considerando suas crencas, desejos e vivencias. Frente a morte, o ser humano pode vir a se atualizar em sua propria existencia, permitindo-se experimentar, mesmo naquele momento de luto e de inseguranca, um equilibrio emocional e mental.
Toward Rigorous Object-Code Coverage Criteria (2017)

Object-branch coverage (OBC) is often used as a measure of the thoroughness of tests suites, augmenting or substituting source-code based structural criteria such as branch coverage and modified condition/decision coverage (MC/DC). In addition, with the increasing use of third-party components for which source-code access may be unavailable, robust object-code coverage criteria are essential to assess how well the components are exercised during testing. While OBC has the advantage of being programming language independent and is amenable to non-intrusive coverage measurement techniques, variations in compilers and the optimizations they perform can substantially change the structure of the generated code and the instructions used to represent branches. To address the need for a robust object coverage criterion, this paper proposes a rigorous definition of OBC such that it captures well the semantics of source code branches for a given instruction set architecture. We report an empirical assessment of these criteria for the Intel x86 instruction set on several examples from embedded control systems software. Preliminary results indicate that object-code coverage can be made robust to compilation variations and is comparable in its bug-finding efficacy to source level MC/DC.
CHEMO‐FREE TRIPLET COMBINATION OF TGR‐1202, UBLITUXIMAB, AND IBRUTINIB IS WELL TOLERATED AND HIGHLY ACTIVE IN PATIENTS WITH ADVANCED CLL AND NHL. (2017)

Introduction: Novel targeted agents are emerging for B-cell malignancies, but few studies have safely combined these agents. Ublituximab (UTX) is a novel glycoengineered mAb targeting a unique epitope on the CD20 antigen. TGR-1202 is a next generation, once daily, PI3Kδ inhibitor, demonstrating a favorable safety profile compared to prior inhibitors, including in long-term follow up (Burris, 2016). This Ph 1 trial evaluates the safety/efficacy of the triplet combination of a novel anti-CD20 mAb + PI3Kδ + BTK inhibitor (ibrutinib) in pts with B-cell malignancies. Methods: Eligible pts had CLL or rel/ref NHL w/o limit to prior therapies, including those ref to prior PI3Kδ or BTK inhibitors. UTX dosed on D 1, 8, 15 of C 1, D 1 of C 2-6, and C 9 & 12. TGR-1202 dose escalated (400/600/800 mg QD), ibrutinib dosed at 420 mg (CLL) or 560 mg (NHL), both on C1D1. Results: 38 pts were enrolled: 20 CLL/SLL and 18 NHL, including 6 follicular (FL), 6 DLBCL, 4 mantle cell (MCL) and 2 marginal zone (MZL). Med age 65 yrs (range 32-85); 29 M/9 F; med prior tx = 3 (range 0-6). 2 pts ref to prior PI3Kδ /2 prev treated with ibrutinib (1 ref/1 rel). MTD was not reached. Most common (> 20%) all causality AE's were fatigue (42%), diarrhea (39%), dizziness (34%), nausea (32%), neutropenia, pyrexia, rash, infusion reaction, insomnia (each at 29%), thrombocytopenia, cough (each at 26%), anemia (24%) and sinusitis (21%). GR 3/4 AE's (all causality) were minimal, the only event >10% was neutropenia (16%). ORR amongst 36 evaluable pts was as follows: 53% of evaluable CLL pts had high-risk cytogenetics and 4/6 DLBCL pts were non-GCB. One CLL pt (17p/11q del) ref to PI3Kδ and ibrutinib achieved a CR. Med time on study is 10 mos (range 1 – 27 mos). Med DOR not reached (range 3 – 24 mos). Conclusions: This is the first known triplet combination of an anti-CD20 mAb + PI3Kδ + BTK inhibitor. The combination of UTX, TGR-1202, and ibrutinib has been well tolerated with activity observed across heavily pre-treated and high-risk B-cell malignancies. Expansion cohorts at the highest dose (800 mg TGR-1202 + full dose ibrutinib) are underway. Future trials for the triplet are warranted. Keywords: chronic lymphocytic leukemia (CLL); ibrutinib; PI3K/AKT/mTOR.
P-Q decoupled state estimation algorithm based on robust theory (2007)

Sate estimation is an important part of EMS,it has important sense in advancing the calculation precision of state estimation.Based on the widely employed P-Q decoupled state estimation method,and M-estimation in robust theory,a set of weight function is conformed,and then the weight value is corrected refering to the ratio between measurement’s residual and measurement from the second calculation.Therefore the weight value of the bad data is less and less,and the bad data’s effect to after calculation is weakened.Finally,taking one area’s 220kV power network as real background and doing simulation experiment using Matlab,it is proved that the new method is simple and practical,and has a good effect in advancing calculation precision of state estimation and weakening the bad data’s effect.
Passing for "normal": Features that affect the community inclusion of people with mental illness. (2009)

These data suggest that stigma is not elicited simply by the presence of a person with a mental illness, and that the presence of a mental illness in most cases only becomes apparent through social interaction. Also, these data support conclusions that personal experience with people with mental illness reduces fear and increases benevolence and that personal contact should be integral to community integration and anti-stigma campaigns.
Entanglement from Tensor Networks on a Trapped-Ion Quantum Computer (2022)

The ability to selectively measure, initialize, and reuse qubits during a quantum circuit enables a mapping of the spatial structure of certain tensor-network states onto the dynamics of quantum circuits, thereby achieving dramatic resource savings when simulating quantum systems with limited entanglement. We experimentally demonstrate a significant benefit of this approach to quantum simulation: the entanglement structure of an infinite system-specifically the half-chain entanglement spectrum-is conveniently encoded within a small register of "bond qubits" and can be extracted with relative ease. Using Honeywell's model H0 quantum computer equipped with selective midcircuit measurement and reset, we quantitatively determine the near-critical entanglement entropy of a correlated spin chain directly in the thermodynamic limit and show that its phase transition becomes quickly resolved upon expanding the bond-qubit register.
Electrokinetic strengthening of soft clay (2009)

The use of electrokinetic treatment to decrease the water content and increase the shear strength, preconsolidation pressure and axial load capacity of a laboratory-prepared soft clay soil was investigated. The tests were carried out in four identical electrokinetic cells. The cell has a volume capacity of 10 litres. A DC voltage of 10 V was applied in the tests investigating the water content, shear strength and preconsolidation pressure. A DC voltage of 5 V was used in the tests investigating the axial load capacity. The energy consumption for each test was 54 W h. The electrokinetic treatment decreased the water content across most of the cell with the lowest water content near the anode (32·8 ± 2% in comparison with 52·7 ± 2·7% in the control) and increased the undrained shear strength across the cell with the highest shear strength reported near the anode (62·5 ± 6·2 kPa in comparison with 6·3 ± 2·1 kPa in the control). Electrokinetic treatment increased the preconsolidation pressure across the cell with the maximum pseudo-preconsolidation pressure near the anode (91 kPa in comparison with pre-loaded surcharge pressure of 10 kPa). The axial load capacity of the foundation model after the treatment was 156 N when the foundation model was serving as the anode and 173 N when the model was not used as an electrode. The loss in the mass of the foundation model by corrosion was 4·7% for the former and 0·4% for the latter.
Comparison of Osteogenic Potential Between Apatite-Coated Poly(Lactide-Co-Glycolide)/Hydroxyapatite Particulates and Bio-Oss (2008)

Previously, we developed a poly(lactide-co-glycolide)/nano-hydroxyapatite (PLGA/HA) composite that overcame the limitations of conventional ceramic bone substitutes. This was achieved by introducing a bone-like apatite layer on the composite to further enhance its osteogenic potential. In this study, we compared the osteogenic potential of the apatite-coated PLGA/HA particulates to that of Bio-Oss, a deproteinized bovine bone material. A mixture of fibrin gel and either apatite-coated PLGA/HA particulates or Bio-Oss was implanted into critical-size rat calvarial defects. As a control, fibrin gel was implanted alone into the defects. At eight weeks after treatment, histological examination showed new bone formation around the grafting materials, and bone formation was similar between the two groups. In the control group, bone was not regenerated and the defects were filled with fibrous tissues. This study showed that a synthetic bone graft material, apatite-coated PLGA/HA particulates, had a comparable bone regeneration potential to the bovine-derived bone graft material, Bio-Oss.
A Measurement Method of Three-Dimensional Surface Morphology Based on Depth-from-Focus through Linear Magnification Calibration (2005)

Errors resulting from magnification variations of a optical system are largely generated in three-dimensional shape measurements based on depth-from-focus. In the case of measuring the surface morphology of tiny objects based on DFF, images are acquired with a very small interval so that magnification changes can be minimized. However, the magnification variations are actually existed in the acquired images and so focus measures are wrongly or ambiguously extracted. In this paper, a methodology with linear magnification calibrations, based on DFF, is proposed to make more accurate measurement in surface morphology with high depth discontinuity, compared with previous ones. Several experiments show that the proposed method outperforms existing ones without magnification calibrations.
Analysis of Mobile Edge Computing for Vehicular Networks (2019)

Vehicular ad-hoc Networks (VANETs) are an integral part of intelligent transportation systems (ITS) that facilitate communications between vehicles and the internet. More recently, VANET communications research has strayed from the antiquated DSRC standard and favored more modern cellular technologies, such as fifth generation (5G). The ability of cellular networks to serve highly mobile devices combined with the drastically increased capacity of 5G, would enable VANETs to accommodate large numbers of vehicles and support range of applications. The addition of thousands of new connected devices not only stresses the cellular networks, but also the computational and storage requirements supporting the applications and software of these devices. Autonomous vehicles, with numerous on-board sensors, are expected to generate large amounts of data that must be transmitted and processed. Realistically, on-board computing and storage resources of the vehicle cannot be expected to handle all data that will be generated over the vehicles lifetime. Cloud computing will be an essential technology in VANETs and will support the majority of computation and long-term data storage. However, the networking overhead and latency associated with remote cloud resources could prove detrimental to overall network performance. Edge computing seeks to reduce the overhead by placing computational resources nearer to the end users of the network. The geographical diversity and varied hardware configurations of resource in a edge-enabled network would require careful management to ensure efficient resource utilization. In this paper, we introduce an architecture which evaluates available resources in real-time and makes allocations to the most logical and feasible resource. We evaluate our approach mathematically with the use of a multi-criteria decision analysis algorithm and validate our results with experiments using a test-bed of cloud resources. Results demonstrate that an algorithmic ranking of physical resources matches very closely with experimental results and provides a means of delegating tasks to the best available resource.
Learning to Answer Subjective, Specific Product-Related Queries using Customer Reviews by Adversarial Domain Adaptation (2019)

Online customer reviews on large-scale e-commerce websites, represent a rich and varied source of opinion data, often providing subjective qualitative assessments of product usage that can help potential customers to discover features that meet their personal needs and preferences. Thus they have the potential to automatically answer specific queries about products, and to address the problems of answer starvation and answer augmentation on associated consumer Q & A forums, by providing good answer alternatives. In this work, we explore several recently successful neural approaches to modeling sentence pairs, that could better learn the relationship between questions and ground truth answers, and thus help infer reviews that can best answer a question or augment a given answer. In particular, we hypothesize that our adversarial domain adaptation-based approach, due to its ability to additionally learn domain-invariant features from a large number of unlabeled, unpaired question-review samples, would perform better than our proposed baselines, at answering specific, subjective product-related queries using reviews. We validate this hypothesis using a small gold standard dataset of question-review pairs evaluated by human experts, significantly surpassing our chosen baselines. Moreover, our approach, using no labeled question-review sentence pair data for training, gives performance at par with another method utilizing labeled question-review samples for the same task.
Dynamic translation of structured Loads/Stores and register mapping for architectures with SIMD extensions (2017)

More and more modern processors have been supporting non-contiguous SIMD data accesses. However, translating such instructions has been overlooked in the Dynamic Binary Translation (DBT) area. For example, in the popular QEMU dynamic binary translator, guest memory instructions with strides are emulated by a sequence of scalar instructions, leaving a significant room for performance improvement when the host machines have SIMD instructions available. Structured loads/stores, such as VLDn/VSTn in ARM NEON, are one type of strided SIMD data access instructions. They are widely used in signal processing, multimedia, mathematical and 2D matrix transposition applications. Efficient translation of such structured loads/stores is a critical issue when migrating ARM executables to other ISAs. However, it is quite challenging since not only the translation of structured loads/stores is not trivial, but also the difference between guest and host register configurations must be taken into consideration. In this work, we present the design and implementation of translating structured loads/stores in DBT, including target code generation as well as efficient SIMD register mapping. Our proposed register mapping mechanisms are not limited to handling structured loads/stores, they can be extended to deal with normal SIMD instructions. On a set of OpenCV benchmarks, our QEMU-based system has achieved a maximum speedup of 5.41x, with an average improvement of 2.93x. On a set of BLAS benchmarks, our system has also obtained a maximum speedup of 2.19x and an average improvement of 1.63x.