gebhart/patrepeval huggingface dataset:
Potential utilization of date palm wood as composite reinforcement (2015)

This research reports the results of an experimental study on the physical, chemical, and mechanical properties as well as the thermal behavior of eight varieties of date palm residues coming from the same environment. The aim is to evaluate each variety of this natural material to be used thereafter, individually or as a mixture, in the manufacturing of composite materials. The results show that Rachis variety exhibits relatively high values of tensile strength and Young’s modulus; they attained 213 MPa and 8.5 GPa, respectively. In contrast, Petiole variety exhibits relatively high values of specific mechanical properties. This is due to its low value of bulk density, which is 0.160 g/cm 3 . Besides that, Petiole variety is also characterized by relatively high porosity and high rate of water absorption; they reached 81.52 and 140%, respectively. Results of thermal analysis show that Leaflets variety provides the highest resistance to thermal degradation; its main degradation occurred at 360℃.
Effects of Anti-VEGF on Pharmacokinetics, Biodistribution, and Tumor Penetration of Trastuzumab in a Preclinical Breast Cancer Model (2012)

Both human epidermal growth factor receptor 2 (HER-2/neu) and VEGF overexpression correlate with aggressive phenotypes and decreased survival among breast cancer patients. Concordantly, the combination of trastuzumab (anti-HER2) with bevacizumab (anti-VEGF) has shown promising results in preclinical xenograft studies and in clinical trials. However, despite the known antiangiogenic mechanism of anti-VEGF antibodies, relatively little is known about their effects on the pharmacokinetics and tissue distribution of other antibodies. This study aimed to measure the disposition properties, with a particular emphasis on tumor uptake, of trastuzumab in the presence or absence of anti-VEGF. Radiolabeled trastuzumab was administered alone or in combination with an anti-VEGF antibody to mice bearing HER2-expressing KPL-4 breast cancer xenografts. Biodistribution, autoradiography, and single-photon emission computed tomography-X-ray computed tomography imaging all showed that anti-VEGF administration reduced accumulation of trastuzumab in tumors despite comparable blood exposures and similar distributions in most other tissues. A similar trend was also observed for an isotype-matched IgG with no affinity for HER2, showing reduced vascular permeability to macromolecules. Reduced tumor blood flow (P < 0.05) was observed following anti-VEGF treatment, with no significant differences in the other physiologic parameters measured despite immunohistochemical evidence of reduced vascular density. In conclusion, anti-VEGF preadministration decreased tumor uptake of trastuzumab, and this phenomenon was mechanistically attributed to reduced vascular permeability and blood perfusion. These findings may ultimately help inform dosing strategies to achieve improved clinical outcomes.
Traditional Chinese medicine Jianpi therapy in exercise-induced fatigue (2022)

The conclusion of our research will provide evidence to support traditional Chinese medicine Jianpi therapy as an effective intervention for patients with EIF.OSF Registration DOI: 10.17605/OSF.IO/NRKX4.
Murine passive cutaneous anaphylaxis test (PCA) for the‘all or none’determination of allergenicity of bovine whey proteins and peptides (1987)

A passive cutaneous anaphylaxis test (PCA) for determination of the allergenicity of bovine whey proteins and peptides was developed in mice. Antisera against whey proteins raised in rabbits and in mice, using a procedure for high IgE titre mixed with Freund's incomplete adjuvant, were applied intradermally, and various whey proteins and whey protein hydrolysates were tested for positive PCA reaction. Unhydrolysed whey and peptides larger than 6500 Da were found to react positively, peptides between 6500 Da and 3400 Da reacted weakly, whereas peptides smaller than 3400 Da were unable to initiate a reaction. The studies indicate that guinea-pigs, widely used by tradition, may be successfully replaced by mice in determination of the allergenicity of various compounds. The sensitivity of the two species is similar, but the husbandry and handling of mice is more convenient, and they are less expensive.
Comparative Biology of IncQ and IncQ-Like Plasmids (2001)

Plasmids belonging to Escherichia coli incompatibility group Q are relatively small (approximately 5 to 15 kb) and able to replicate in a remarkably broad range of bacterial hosts. These include gram-positive bacteria such as Brevibacterium and Mycobacterium and gram-negative bacteria such as Agrobacterium, Desulfovibrio, and cyanobacteria. These plasmids are mobilized by several self-transmissible plasmids into an even more diverse range of organisms including yeasts, plants, and animal cells. IncQ plasmids are thus highly promiscuous. Recently, several IncQ-like plasmids have been isolated from bacteria found in environments as diverse as piggery manure and highly acidic commercial mineral biooxidation plants. These IncQ-like plasmids belong to different incompatibility groups but have similar broad-host-range replicons and mobilization properties to the IncQ plasmids. This review covers the ecology, classification, and evolution of IncQ and IncQ-like plasmids.
Consequences of ChemR23 Heteromerization with the Chemokine Receptors CXCR4 and CCR7 (2013)

Recent studies have shown that heteromerization of the chemokine receptors CCR2, CCR5 and CXCR4 is associated to negative binding cooperativity. In the present study, we build on these previous results, and investigate the consequences of chemokine receptor heteromerization with ChemR23, the receptor of chemerin, a leukocyte chemoattractant protein structurally unrelated to chemokines. We show, using BRET and HTRF assays, that ChemR23 forms homomers, and provide data suggesting that ChemR23 also forms heteromers with the chemokine receptors CCR7 and CXCR4. As previously described for other chemokine receptor heteromers, negative binding cooperativity was detected between ChemR23 and chemokine receptors, i.e. the ligands of one receptor competed for the binding of a specific tracer of the other. We also showed, using mouse bone marrow-derived dendritic cells prepared from wild-type and ChemR23 knockout mice, that ChemR23-specific ligands cross-inhibited CXCL12 binding on CXCR4 in a ChemR23-dependent manner, supporting the relevance of the ChemR23/CXCR4 interaction in native leukocytes. Finally, and in contrast to the situation encountered for other previously characterized CXCR4 heteromers, we showed that the CXCR4-specific antagonist AMD3100 did not cross-inhibit chemerin binding in cells co-expressing ChemR23 and CXCR4, demonstrating that cross-regulation by AMD3100 depends on the nature of receptor partners with which CXCR4 is co-expressed.
Design for the discrete cosine transform in VLSI (1998)

The discrete cosine transform is reviewed with the aid of recent implementations of the 8 × 8 transform. The distinct roles of algorithmic and multiplier design are identified, and key circuit and logic innovations are highlighted.
Nucleotide metabolism in spleen and peripheral blood lymphocytes during theophylline treatment. (1984)

The in vivo effect of theophylline on lymphocyte nucleotide metabolism was investigated. Rat peripheral blood lymphocytes presented more elevated levels of adenosine 5'-triphosphate (ATP) and cyclic adenosine 3',5'-monophosphate (cAMP) than shown by spleen lymphocytes. A continuous (15 days) daily oral treatment of the rats with aminophylline increased intralymphocytic cAMp content in peripheral blood (by 14 times) and in spleen lymphocytes (by 4 times), whereas ATP content was not significantly changed. NAD+ and NADH levels and NAD+/NADH ratios appeared higher in peripheral blood than in spleen cells, and were not influenced by aminophylline treatment. These results may be explained by assuming the existence of a different distribution of lymphocyte subpopulations and of a different sensitivity of the same to aminophylline treatment. The studies of nucleotide variation in peripheral blood lymphocytes incubated at 37 degrees C in anoxic conditions (N2+CO2, 95:5) revealed an impairment of ATP production and a well-preserved redox state.
Ryanodine: a modifier of sarcoplasmic reticulum calcium release in striated muscle. (1985)

We have proposed that the naturally occurring alkaloid ryanodine reduces the release of calcium from the sarcoplasmic reticulum (SR) in cardiac muscle cells. We summarize the data that support this hypothesis and discuss possible mechanisms for 1) the differences in sensitivity to ryanodine displayed by intact skeletal and cardiac muscle preparations vs. that of skinned cardiac cells and isolated SR membranes, 2) the ability of ryanodine to cause either an increase or a decrease in calcium accumulation by isolated skeletal muscle SR vesicles depending on experimental conditions, and 3) the positive inotropic effects produced by ryanodine in cardiac muscle preparations under certain experimental circumstances. In addition, we also show how ryanodine can be used to evaluate the contributions made by SR calcium release to cellular events in striated muscle.
Predicting responsiveness to sorafenib: can the determination of FGF3/FGF4 amplifications enrich for clinical benefit? (2014)

A small proportion of patients with advanced hepatocellular carcinoma harbor FGF3/4 gene amplifications in an 11q13 amplicon. A recent report suggests that the presence of this alteration might enrich for sensitivity to sorafenib. Further, there is growing evidence that interference with the FGF/FGFR axis has therapeutic potential in patients with advanced hepatocellular carcinoma.
Mitochondrial proteome: Altered cytochrome <b> <i>c</i> </b> oxidase subunit levels in prostate cancer (2003)

Laser capture microdissection was combined with reverse phase protein lysate arrays to quantitatively analyze the ratios of mitochondrial encoded cytochrome c oxidase subunits to nuclear encoded cytochrome c oxidase subunits, and to correlate the ratios with malignant progression in human prostate tissue specimens. Cytochrome c oxidase subunits I-III comprise the catalytic core of the enzyme and are all synthesized from mitochondrial DNA. The remaining subunits (IV-VIII) are synthesized from cellular nuclear DNA. A significant (P < 0.001, 30/30 prostate cases) shift in the relative concentrations of nuclear encoded cytochrome c oxidase subunits IV, Vb, and VIc compared to mitochondrial encoded cytochrome c oxidase subunits I and II was noted during the progression of prostate cancer from normal epithelium through premalignant lesions to invasive carcinoma. Significantly, this shift was discovered to begin even in the premalignant stage. Reverse phase protein lysate array-based observations were corroborated with immunohistochemistry, and extended to a few human carcinomas in addition to prostate. This analysis points to a role for nuclear DNA encoded mitochondrial proteins in carcinogenesis; underscoring their potential as targets for therapy while highlighting the need for full characterization of the mitochondrial proteome.
Content and context information fusion for mobile landmark recognition (2011)

This paper proposes a new information fusion approach that employs two information components for mobile landmark recognition, which includes: content analysis and context analysis. Existing landmark recognition works are mainly based on PC platform, which uses content analysis alone for recognition, and thus has a large computation cost and cannot satisfy mobile users' fast response time requirements. Therefore in this paper, a mobile platform-based landmark recognition system is developed. The bag-of-words method is employed and further improved as content analysis according to the specific features of landmark images. Context analysis based on location (obtained by global positioning system) and direction (obtained by digital compass) information is then integrated with improved BoW as a new information fusion approach for mobile landmark recognition. Finally, the experiment results conducted on the NTU landmark database show that the proposed approach is effective for mobile landmark recognition.
STUDIES ON THE PHOTOCATALYTIC DEGRADATION OF ORGANIC DYES USING CeO2 - ZnO MIXED OXIDES (2015)

A new catalytic mixture of nanosized dioxide (CeO 2 ) and zinc oxide (ZnO) powders have been synthesized by surfactant-assisted solvo-thermal route, characterized and evaluated for photocatalytic activity.The prepared catalysts were characterized by TG, XRD, SEM and EDAX methods.SEM analysis showed that the catalyst particles have spheroidal shape and their sizes range from 50 to 80 nm, organised as uniform distributed aggregates with large surface area, leading to the existence of a large number of defects.The photocatalytic activity of these materials was evaluated by UV-Vis spectroscopy for degradation of methylene blue (MB) and 4'-(1-methyl-benzimidazoyl-2)-phenylazo-2"-(8"-amino-1"-hydroxy-3",6"-disulphonic)-naphthalene acid (PMBH) in water.
Controlled synthesis of poly(3-hexylthiophene) in continuous flow (2013)

There is an increasing demand for organic semiconducting materials with the emergence of organic electronic devices. In particular, large-area devices such as organic thin-film photovoltaics will require significant quantities of materials for device optimization, lifetime testing and commercialization. Sourcing large quantities of materials required for the optimization of large area devices is costly and often impossible to achieve. Continuous-flow synthesis enables straight-forward scale-up of materials compared to conventional batch reactions. In this study, poly(3-hexylthiophene), P3HT, was synthesized in a bench-top continuous-flow reactor. Precise control of the molecular weight was demonstrated for the first time in flow for conjugated polymers by accurate addition of catalyst to the monomer solution. The P3HT samples synthesized in flow showed comparable performance to commercial P3HT samples in bulk heterojunction solar cell devices.
Laboratory investigation of shale rock to identify fracture propagation in vertical direction to bedding (2018)

Affected by beddings and natural fractures, fracture geometry in the vertical plane is complex in shale formation, which differs from a simple fracture in homogeneous sandstone reservoirs. However, the propagation mechanism of a hydraulic fracture in the vertical plane has not been well understood. In this paper, a true tri-axial pressure machine was deployed for shale horizontal well fracturing simulation experiments of shale outcrops. The effects of multiple factors on hydraulic fracture vertical propagation were studied. The results revealed that hydraulic fracture initiation and propagation displayed four basic patterns in the vertical plane of laminated shale formation. A hydraulic fracture would cross the beddings under the high vertical stress difference between a vertical stress and horizontal minimum stress of 12 MPa, while a hydraulic fracture propagates along the beddings under a low vertical stress difference of 3 MPa. Four kinds of fracture geometry, including a single main fracture, a nonplanar fracture, a complex fracture, and a complex fracture network, were observed due to the combined effects of flow rate and viscosity. Due to the influence of binding strength (or cementing strength) on the fracture communication effects between a hydraulic fracture and the beddings, the opening region of the beddings takes the shape of an ellipse.
Electronegative LDL: A Circulating Modified LDL with a Role in Inflammation (2013)

Electronegative low density lipoprotein (LDL(-)) is a minor modified fraction of LDL found in blood. It comprises a heterogeneous population of LDL particles modified by various mechanisms sharing as a common feature increased electronegativity. Modification by oxidation is one of these mechanisms. LDL(-) has inflammatory properties similar to those of oxidized LDL (oxLDL), such as inflammatory cytokine release in leukocytes and endothelial cells. However, in contrast with oxLDL, LDL(-) also has some anti-inflammatory effects on cultured cells. The inflammatory and anti-inflammatory properties ascribed to LDL(-) suggest that it could have a dual biological effect.
Efficient streaming of 3D scenes with complex geometry and complex lighting (2008)

Streaming data to efficiently render complex 3D scenes in presence of global illumination is still a challenging task. In this paper, we introduce a new data structure based on a 3D grid of irradiance vectors to store the indirect illumination appearing on complex and detailed objects: the Irradiance Vector Grid (IVG). This representation is independent of the geometric complexity and is suitable for quantization to different quantization schemes. Moreover, its streaming over network involves only a small overhead compared to detailed geometry, and can be achieved independently of the geometry. Furthermore, it can be efficiently rendered using modern graphics hardwar. We demonstrate our new data structure in a new remote 3D visualization system, that integrates indirect lighting streaming and progressive transmission of the geometry, and study the impact of different strategies on data transfer.
ROLE OF COMPONENTS OF microRNA MACHINERY IN CARCINOGENESIS (2018)

MicroRNAs (miRNAs) are a broad class of non-coding RNAs nearly 21 nucleotides length, which play crucial functions in post-transcriptional gene regulation. These molecules are associated with many developmental and cellular processes in eukaryotic organisms. Current investigation has reported major factors contributing to miRNA biogenesis and has constituted basic principles of miRNA function. More recently, it was confirmed that various miRNAs are clearly implicated in human malignancies, such as lung, breast, ovarian, bladder, colon cancer and other kinds of carcinoma. In addition, dysregulation in the miRNA machinery elements such as Dicer, Drosha, DGCR8, Argonaut, and TRBP could be involved in the progress of many tumor types. The purpose of the current review was to compile growing information besides how miRNA biogenesis and gene silencing are modified to develop cancer.
Service-Oriented Architecture: Concepts, Technology, and Design (2006)

Many of the designations used by manufacturers and sellers to distinguish their products are claimed as trademarks. Where those designations appear in this book, and the publisher was aware of a trademark claim, the designations have been printed with initial capital letters or in all capitals. The authors and publisher have taken care in the preparation of this book, but make no expressed or implied warranty of any kind and assume no responsibility for errors or omissions. No liability is assumed for incidental or consequential damages in connection with or arising out of the use of the information or programs contained herein. The publisher offers excellent discounts on this book when ordered in quantity for bulk purchases or special sales, which may include electronic versions and/or custom covers and content particular to your business, training goals, marketing focus, and branding interests. For more information, please contact: U. S. Corporate and Government Sales
Robust Position Control of Electro Hydrostatic Actuator with System Uncertainties Using Sliding Mode Control and Neural Networks Algorithm (2011)

Robust Position Control of Electro Hydrostatic Actuator with System Uncertainties Using Sliding Mode Control and Neural Networks Algorithm Kyoung Taik Park; Han Me Kim Pages 1255-1260 (2011 Proceedings of the 28th ISARC, Seoul, Korea, ISBN 978-89-954572-4-5, ISSN 2413-5844) Abstract: This paper deals with robust position control of electro-hydrostatic actuator (EHA) systems with system uncertainties. EHA systems compared with conventional hydraulic actuator (CHA) systems are controlled by electric motor directly connected to bidirectional pump and its size is much smaller due to the component integration such as a pump, a reservoir, various valves and horses. In addition, EHA systems have fast response property because of high stiffness. Therefore, EHA systems can replace CHA systems as well as satisfy system performance. In spite of the merit of EHA systems, EHA systems in construction field are exposed to many system uncertainties due to the distinct characteristics of construction field. However, it is difficult to measure or estimate system uncertainties. Thus, sliding mode controller (SMC) and radial basis function neural networks (RBFNNs) algorithm are designed to compensate system uncertainties and to achieve robust control performance with EHA systems. Keywords: Electro-hydraulic Actuator, System Uncertainty, Sliding Mode Control, Radial Basis Function Neural Networks DOI: https://doi.org/10.22260/ISARC2011/0232 Download fulltext Download BibTex Download Endnote (RIS) TeX Import to Mendeley
Achromatization of Wollaston polarizing beam splitters (2011)

We describe the achromatization of Wollaston prisms to reduce the angular dispersion in the splitting angle. Analytical theory and ray-tracing modeling is presented. In an example application, a sixfold reduction in dispersion is achieved for wavelengths in the region 400 nm to 1.7 μm. Experimental proof of concept is demonstrated, and in an example application, the spectral dispersion of extended images recorded through cascaded Wollaston prisms is shown to be reduced by an order of magnitude.
Liver cancer incidence and mortality in China: Temporal trends and projections to 2030 (2018)

Based on the analysis, incidence and mortality rates of liver cancer are expected to decrease through 2030, but the burden of liver cancer is still serious in China, especially in rural and western areas. Most cases of liver cancer in China can be prevented through vaccination and more prevention efforts should be focused on high risk groups.
Gas analysis procedures applicable to flue gas desulfurization by the citrate process (1979)

The citrate process for sulfur dioxide emission control was developed in pursuit of the Bureau of Mines goal of minimizing the adverse environmental impact of mineral-processing operations. This publication describes the gas analysis procedures used during development of the process. The research required the capability to analyze SO/sub 2/, H/sub 2/S, CO, CO/sub 2/, COS, volatile hydrocarbons, NO, NO/sub 2/, O/sub 2/, N/sub 2/, and H/sub 2/. The methods described include gas chromatography, electrochemical detection, infrared spectroscopy, and the use of a computer program to predict the product composition in complex reactions. Laboratory and pilot plant applications are discussed.
Approximating quantiles in very large datasets (2010)

Very large datasets are often encountered in climatology, either from a multiplicity of observations over time and space or outputs from deterministic models (sometimes in petabytes= 1 million gigabytes). Loading a large data vector and sorting it, is impossible sometimes due to memory limitations or computing power. We show that a proposed algorithm to approximating the median, "the median of the median" performs poorly. Instead we develop an algorithm to approximate quantiles of very large datasets which works by partitioning the data or use existing partitions (possibly of non-equal size). We show the deterministic precision of this algorithm and how it can be adjusted to get customized precisions.