gebhart/patrepeval huggingface dataset:
Lure and Toxicant System for the Cabbage Looper (Lepidoptera: Noctuidae) (1991)

A lure and toxicant system for killing cabbage looper, Trichoplusia ni (Hübner), moths was developed based on moth attraction to and feeding at flowers. Unmated females were attracted to the floral compound phenylacetaldehyde formulated for release at 20-4,000 ng/h. Attracted moths were stimulated to feed at bait stations loaded with sugar solutions when placed near phenylacetaldehyde dispensers. All feeding moths were killed when 0.2% methomyl was added to the sucrose solutions. A combination phenylacetaldehyde sucrose-methomyl dispenser tested in a field cage resulted in 61% mortality of female moths and 44% of male moths released.
A New Technique to Eliminate the 90<sup>°</sup> Domains in BaTiO<sub>3</sub> Crystal Fibers (2000)

A non-destructive method to eliminate the 90° domains in BaTiO 3 crystal fibers has been developed. We employ a vibration system to apply a cyclic force on the a-faces of the crystals. An accumulation of the vibrating force achieves a higher force, which dissipates the internal stress of the crystal. The results show that the 90° domains are easily diminished with only a slight force pressed to the crystal surface.
Abstract LB-006: Intracellular protein therapy with SOCS3 utilizing aMTD-enabled macromolecule intracellular transduction technology (MITT) (2018)

Abstract Background Macromolecule intracellular transduction technology (MITT), a platform for the discovery/development of new medicinal drugs, is enabled with a new generation of hydrophobic cell-penetrating peptides (CPPs), termed advanced macromolecule transduction domains (aMTDs). Originally derived from the hydrophobic signal peptides of secreted proteins, earlier generations of MTDs were hampered by poor solubility and less efficient cell-permeability. The MITT platform addresses these limitations, first, by the design of synthetic aMTD sequences that incorporate 6 critical factors found to enhance the intracellular delivery of proteins into cells and tissues and second, by the use of humanized solubilization domains to enhance the solubility of aMTD-containing recombinant proteins. Object The goal of this study is to develop and evaluate an aMTD-SOCS3 (suppressor of cytokine signaling 3) protein (iCP-SOCS3) as cell-permeable biotherapeutic to selectively target tumors dependent on JAK/STAT signaling and to compare the cell-/tissue-penetration efficiencies of iCP-SOCS3 with a previous generation of cell-permeable SOCS3 (MTM-SOCS3: CP-SOCS3) enabled by a hydrophobic CPP, termed membrane translocating motif (MTM) derived from the signal peptide of fibroblast growth factor 4 (FGF4). Results Solubility (up to 10 mg/ml) and final yields of E. coli produced iCP-SOCS3 (60 mg/L) were sufficient for clinical development; whereas, CP-SOCS3 suffered from low solubility and yields (0.4 mg/ml and 0.2 mg/L, respectively). Cellular uptake of fluorescent iCP-SOCS3 was enhanced by 25-fold as compared to CP-SOCS3 as assessed by flow cytometry, and delivery and persistence of the protein in a variety of tissues (heart, lung, spleen, kidney, liver and brain) were similarly increased. In addition, aMTD promoted the cell-to-cell transfer of SOCS3 protein, and the transferred iCP-SOCS3 was biochemically active as assessed by inhibition of IFN-γ-induced phosphorylation of STAT1 and STAT3 with concomitant suppression of cancer-associated phenotypes in cultured cells and in mice bearing human tumor xenografts (90% inhibition of proliferation and 84% inhibition of migration in PANC-1 cells, and 85% suppression of pancreatic tumor growth, respectively). Conclusion These results provide further validation of MITT as a platform to develop protein-based biotherapeutics, and suggest the use of iCP-SOCS3 as a novel protein therapy against tumors dependent on JAK/STAT signaling. Citation Format: Youngsil Choi, Seulmee Shin, Kuysook Lee, Daewoong Jo. Intracellular protein therapy with SOCS3 utilizing aMTD-enabled macromolecule intracellular transduction technology (MITT) [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2018; 2018 Apr 14-18; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2018;78(13 Suppl):Abstract nr LB-006.
Quantitative Assessment of Hydrocarbon Contamination in Soil Using Reflectance Spectroscopy: A “Multipath” Approach (2013)

Petroleum hydrocarbons are contaminants of great significance. The commonly used analytic method for assessing total petroleum hydrocarbons (TPH) in soil samples is based on extraction with 1,1,2-Trichlorotrifluoroethane (Freon 113), a substance prohibited to use by the Environmental Protection Agency. During the past 20 years, a new quantitative methodology that uses the reflected radiation of solids has been widely adopted. By using this approach, the reflectance radiation across the visible, near infrared-shortwave infrared region (400-2500 nm) is modeled against constituents determined using traditional analytic chemistry methods and then used to predict unknown samples. This technology is environmentally friendly and permits rapid and cost-effective measurements of large numbers of samples. Thus, this method dramatically reduces chemical analytical costs and secondary pollution, enabling a new dimension of environmental monitoring. In this study we adapted this approach and developed effective steps in which hydrocarbon contamination in soils can be determined rapidly, accurately, and cost effectively solely from reflectance spectroscopy. Artificial contaminated samples were analyzed chemically and spectrally to form a database of five soils contaminated with three types of petroleum hydrocarbons (PHCs), creating 15 datasets of 48 samples each at contamination levels of 50-5000 wt% ppm (parts per million). A brute force preprocessing approach was used by combining eight different preprocessing techniques with all possible datasets, resulting in 120 different mutations for each dataset. The brute force was done based on an innovative computing system developed for this study. A new parameter for evaluating model performance scoring (MPS) is proposed based on a combination of several common statistical parameters. The effect of dividing the data into training validation and test sets on modeling accuracy is also discussed. The results of this study clearly show that predicting TPH levels at low concentrations in selected soils at high precision levels is viable. Dividing a dataset into training, validation, and test groups affects the modeling process, and different preprocessing methods, alone or in combination, need to be selected based on soil type and PHC type. MPS was found to be a better parameter for selecting the best performing model than ratio of prediction to deviation, yielding models with the same performance but less complicated and more stable. The use of the "all possibilities" system proved to be mandatory for efficient optimal modeling of reflectance spectroscopy data.
FlowToss: Fast Wait-Free Scheduling of Deterministic Flows in Time Synchronized Networks (2021)

Motivated by important industrial automation use cases, such as closed loop motion control and autonomous mobile robots, we study wait-free scheduling of periodic flows with stringent delay and jitter requirements in time sensitive networks. The goal is to assign initial transmission time-slots to periodic flows so that network queuing delays are eliminated or are very small. We make use of Bézour's Identity to develop simple and fast scheduling algorithms for this NP-hard problem. Operating in an online mode, our algorithms can quickly allocate contention free start time-slots to new flows, without changing allocations of already scheduled flows. Our main results are greedy and random scheduling algorithms that can trade speed for solution quality. Our simulations on different network topologies show that these algorithms are computationally efficient and can easily schedule a large number of flows, thus meeting the requirements of many industrial automation use cases.
Monitoring Field Populations of the Sunflower Moth,Homoeosoma electellum(Lepidoptera: Pyralidae), with its Sex Pheromone1 (1982)

Field studies demonstrated that (Z)-9,(E)-12-tetradecadienol (Z 9, E 12-14:OH) is the primary sex pheromone component of the sunflower moth, Homoeosoma electellum (Hulst). Additions of tetradecanol and (Z)-9-tetradecenol, which previously had also been identified in female extracts of this species, did not increase the attractancy of Z 9, E 12-14:OH for target males. Traps baited with 10 μg of Z 9, E 12-14:OH captured significantly more sunflower moth males than traps baited with virgin females. The effects of lure dose of Z 9, E 12-14:OH and of trap location with respect to surrounding vegetation on male captures were studied.
MOS transistors with stacked SiO/sub 2/-Ta/sub 2/O/sub 5/-SiO/sub 2/ gate dielectrics for giga-scale integration of CMOS technologies (1998)

Advances in lithography and thinner SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> gate oxides have enabled the scaling of MOS technologies to sub-0.25-μm feature size. High dielectric constant materials, such as Ta <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">5</sub> , have been suggested as a substitute for SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> as the gate material beyond t/sub ox//spl ap/25 /spl Aring/. However, the Si-Ta <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">5</sub> material system suffers from unacceptable levels of bulk fixed charge, high density of interface trap states, and low silicon interface carrier mobility. We present a solution to these issues through a novel synthesis of a thermally grown SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> (10 /spl Aring/)-Ta <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">5</sub> (MOCVD-50 /spl Aring/)-SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> (LPCVD-5 /spl Aring/) stacked dielectric. Transistors fabricated using this stacked gate dielectric exhibit excellent subthreshold behaviour, saturation characteristics, and drive currents.
Statistical 3D prostate imaging atlas construction via anatomically constrained registration (2013)

Statistical imaging atlases allow for integration of information from multiple patient studies collected across different image scales and modalities, such as multi-parametric (MP) MRI and histology, providing population statistics regarding a specific pathology within a single canonical representation. Such atlases are particularly valuable in the identification and validation of meaningful imaging signatures for disease characterization <i>in vivo</i> within a population. Despite the high incidence of prostate cancer, an imaging atlas focused on different anatomic structures of the prostate, i.e. an anatomic atlas, has yet to be constructed. In this work we introduce a novel framework for MRI atlas construction that uses an iterative, anatomically constrained registration (AnCoR) scheme to enable the proper alignment of the prostate (Pr) and central gland (CG) boundaries. Our current implementation uses endorectal, 1.5T or 3T, T2-weighted MRI from 51 patients with biopsy confirmed cancer; however, the prostate atlas is seamlessly extensible to include additional MRI parameters. In our cohort, radical prostatectomy is performed following MP-MR image acquisition; thus ground truth annotations for prostate cancer are available from the histological specimens. Once mapped onto MP-MRI through elastic registration of histological slices to corresponding T2-w MRI slices, the annotations are utilized by the AnCoR framework to characterize the 3D statistical distribution of cancer per anatomic structure. Such distributions are useful for guiding biopsies toward regions of higher cancer likelihood and understanding imaging profiles for disease extent <i>in vivo</i>. We evaluate our approach via the Dice similarity coefficient (DSC) for different anatomic structures (delineated by expert radiologists): Pr, CG and peripheral zone (PZ). The AnCoR-based atlas had a CG DSC of 90.36%, and Pr DSC of 89.37%. Moreover, we evaluated the deviation of anatomic landmarks, the urethra and veromontanum, and found 3.64 mm and respectively 4.31 mm. Alternative strategies that use only the T2-w MRI or the prostate surface to drive the registration were implemented as comparative approaches. The AnCoR framework outperformed the alternative strategies by providing the lowest landmark deviations.
Dye-sensitized nanocrystalline solar cells based on composite polymer electrolytes containing fumed silica nanoparticles (2004)

We report remarkably high energy conversion efficiency (4.5% at 100 mW cm(-2)) of a dye-sensitized solar cell in the solid state, using composite polymer electrolytes containing fumed silica nanoparticles.
Spectrometric oil analysis. Detecting engine failures before they occur (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSpectrometric oil analysis. Detecting engine failures before they occurKent J. Eisentraut, Rebecca W. Newman, Costandy S. Saba, Robert E. Kauffman, and Wendell E. RhineCite this: Anal. Chem. 1984, 56, 9, 1086A–1094APublication Date (Print):August 1, 1984Publication History Published online22 September 2008Published inissue 1 August 1984https://pubs.acs.org/doi/10.1021/ac00273a002https://doi.org/10.1021/ac00273a002research-articleACS PublicationsRequest reuse permissionsArticle Views299Altmetric-Citations19LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Effects of Soybean Glyceollins and Estradiol in Postmenopausal Female Monkeys (2006)

Glyceollins are a novel class of soybean phytoalexins with potential cancer-protective antiestrogenic effects. The purpose of this study was to evaluate the estrogen-antagonist effects of glyceollin-enriched soy protein on biomarkers for breast cancer risk. Thirty female postmenopausal cynomolgus macaques were randomized to one of three dietary treatments for 3 wk: 1) estradiol (E2, 1 mg/day) + casein/lactalbumin (control); 2) E2 + soy protein isolate (SPI) containing 194 mg/day isoflavonoids; and 3) E2 + glyceollin-enriched soy protein (GLY) containing 189 mg/day isoflavonoids + 134 mg/day glyceollins. Doses are expressed in calorically scaled human equivalents. Mean serum glyceollin concentrations at 4 h postfeeding were 134.2 +/- 34.6 nmol/L in the GLY group and negligible in the SPI group (P = 0.0007). Breast proliferation was significantly increased in the control group (+237%, P = 0.01) but not in the SPI group (+198%, P = 0.08) or GLY group (+36%, P = 0.18). Gene expression of trefoil factor 1 and progesterone receptor, two markers of estrogen receptor activity in breast epithelium, were also significantly higher in the control (P < 0.05 for both) but not in the GLY group. These preliminary findings suggest that soybean glyceollins are natural compounds with potential estrogen-modulating properties in the breast.
Erythropoietin-independent erythrocyte production: signals through gp130 and c-kit dramatically promote erythropoiesis from human CD34+ cells. (1996)

Erythropoietin (EPO) is the primary humoral regulator of erythropoiesis and no other factor has previously been reported to support proliferation and terminal maturation of erythroid cells from hemopoietic stem cells. Here we show that stimulation of glycoprotein (gp130) by a combination of recombinant human soluble interleukin 6 receptor (sIL-6R) and IL-6 but not sIL-6R or IL-6 alone can support proliferation, differentiation, and terminal maturation of erythroid cells in the absence of EPO from purified human CD34+ cells in suspension culture containing stem cell factor (SCF). A number of erythroid bursts and mixed erythroid colonies also developed in methylcellulose culture under the same combination. The addition of anti-gp130 monoclonal antibodies but not anti-EPO antibody to the same culture completely abrogated the generation of erythroid cells. These results clearly demonstrate that mature erythroid cells can be emerged from hemopoietic progenitors without EPO in vitro. Together with the previous reports that human sera contain detectable levels of sIL-6R, IL-6, and SCF, current data suggest that gp130 signaling in association with c-kit activation may play a role in human erythropoiesis in vivo.
Integrated variable optical delay lines using high index contrast waveguide (2004)

Wide-tunable-range optical delay lines are demonstrated in high index contrast waveguides. This device integrates tunable allpass filters, for continuous delay tuning, with cascaded fixed delay waveguides enabling coherent switching and tuning ranges up to 2.56ns.
Three‐Dimensional Microvascular Fiber‐Reinforced Composites (2011)

and materials or lack of scalability and vascular complexity of the fabrication approach. Here we show that the introduction of sacrificial fibers into woven preforms enables the seamless fabrication of 3D microvascular composites that are both strong and multifunctional. Underpinning the method is the efficient thermal depolymerization of catalyst-impregnated polylactide (PLA) fibers with simultaneous evaporative removal of the resulting lactide monomer. The hollow channels produced are high-fidelity inverse replicas of the original fiber’s diameter and trajectory. The method has yielded microvascular fiber-reinforced composites with channels over one meter in length that can be subsequently filled with a variety of liquids including aqueous solutions, organic solvents, and liquid metals. By circulating fluids with unique physical properties, we demonstrate the ability to create a new generation of biphasic pluripotent composite materials in which the solid phase provides strength and form while the liquid phase provides interchangeable functionality. Microvascular composite fabrication begins with the mechanized weaving of sacrifi cial fi bers into 3D woven glass
Surface plasmon broadband continuum (2005)

A new method for optically exciting and visualizing surface plasmons in thin metal films is described. The technique relies on the use of a high numerical aperture objective lens to locally launch surface plasmons with an area much smaller than their lateral decay length. We visualize directly the intensity distribution of the surface plasmons by detecting the intrinsic lossy modes associated with plasmon propagation in thin films. Our approach allowed us to excite simultaneously a broad spectral continuum of surface waves and to describe for the first time surface plasmon rainbow jets. We quantified the attenuation of the jet as a function of wavelength and film thickness and compared it to the different propagation damping mechanisms. We demonstrated the influence of the interface on the surface plasmon propagation length and demonstrated surface plasmon spectral filtering using molecular excitonic adsorbates.
Liquid state NMR Quantum Computing (2000)

This in an introduction on quantum computing and on the use of NMR to build quantum computers, geared towards an NMR audience.
A chromatographically purified human TGF‐β1 fraction from virally inactivated platelet lysates (2011)

A fraction enriched in TGF-β1 can be prepared from virally inactivated human platelet lysates using an easily scale process. Its interest in regenerative medicine and cell therapy will be evaluated in further studies.
Large‐scale functional<i>LIPA</i>variant characterization to improve birth prevalence estimates of lysosomal acid lipase deficiency (2019)

Lysosomal acid lipase (LAL) deficiency is an autosomal recessive disorder caused by LIPA gene mutations that disrupt LAL activity. We performed in vitro functional testing of 149 LIPA variants to increase the understanding of the variant effects on LAL deficiency and to improve disease prevalence estimates. Chosen variants had been reported in literature or population databases. Functional testing was done by plasmid transient transfection and LAL activity assessment. We assembled a set of 165 published LAL deficient patient genotypes to evaluate this assay's effectiveness to recapitulate genotype/phenotype relationships. Rapidly progressive LAL deficient patients showed negligible enzymatic activity (<1%), whereas patients with childhood/adult LAL deficiency typically have 1-7% average activity. We benchmarked six in silico variant effect prediction algorithms with these functional data. PolyPhen-2 was shown to have a superior area under the receiver operating curve performance. We used functional data along with Genome Aggregation Database (gnomAD) allele frequencies to estimate LAL deficiency birth prevalence, yielding a range of 3.45-5.97 cases per million births in European-ancestry populations. The low estimate only considers functionally assayed variants in gnomAD. The high estimate computes allele frequencies for variants absent in gnomAD, and uses in silico scores for unassayed variants. Prevalence estimates are lower than previously published, underscoring LAL deficiency's rarity.
Fast motion estimation based on adaptive search range adjustment and matching error prediction (2009)

This work presents fast motion estimation (ME) by using both an adaptive search range adjustment and a matching error prediction. The basic idea of the proposed scheme is based on adjusting a given search range adaptively and predicting a block matching errors effectively. The adaptive search range adjustment is first performed by analyzing the contents of a scene. Next, the total block matching error is estimated by using partial errors of sub-sampled blocks to eliminate invalid blocks earlier for ME. In order to evaluate the proposed scheme, several baseline approaches are described and compared. The experimental results show that the proposed algorithm can reduce the computational cost more than 81% for ME at the cost of 0.01 dB image quality degradation versus the conventional PDE algorithm1. The main contributions of the proposed approach are that 1) it can reduce the computational cost considerably; 2) it can be applied to conventional PDE algorithms without significant changes; and 3) it can be a useful tool for fast ME in the consumer electronics-related field.
Some chemical aspects of histamine H2-receptor antagonists. (1976)

<P>Abstract copyright UK Data Service and data collection copyright owner.</P>