gebhart/patrepeval huggingface dataset:
Applications of Smartphones for Ubiquitous Health Monitoring and Wellbeing Management (2011)

Advances in smartphone technology and data communications facilitate the use of ubiquitous health monitoring and mobile health application as a solution of choice for the overwhelming problems of the healthcare system. In addition to easier management and seamless access to historical records, ubiquitous technology has the potential to motivate users to take an active role and manage their own conditions. In this paper we present capabilities of the current generation of smartphones and possible applications for ubiquitous health monitoring and wellness management. We describe the architecture and organization of ubiquitous health monitoring systems, Body Sensor Networks, and integration of wearable and environmental sensors. We also describe mainstream mobile health related applications in today’s mobile marketplaces such as Apple App Store and Google Android Marketplace. Finally, we present the development of UAHealth - our integrated mobile health monitoring system for wellness management, designed to monitor physical activity, weight, and heart activity.
Association of<i>EGFR</i>L858R Mutation in Circulating Free DNA With Survival in the EURTAC Trial (2015)

clinicaltrials.gov Identifier: NCT00446225.
Wingbeat frequency, temperature and body size in bees and flies (1984)

ABSTRACT. This paper describes the relationship between ambient temperature and wingbeat frequency in bees and flies of different sizes, and presents new data from insects in free fight. The slope of the relationship changes with the size of the insect, and was different for insects in hovering flight compared with individuals of the same species in forward flight.
Integrated VLSI potentiostat for cyclic voltammetry in electrolytic reactions (2004)

This paper describes a CMOS integrated potentiostatic control circuit. The design maintains a constant bias potential between the reference and working electrodes for an amperometric chemical sensor. A technique of converting input currents into time for amperometric measurements is proposed. Redox currents ranging from 1pA to 200nA can be measured with a maximum non-linearity of /spl plusmn/0.1% over this range. The design can be used to generate a cyclic voltammogram for an electrochemical reaction by sweeping the voltages across the range specified by the user. Analog inputs are processed and digital outputs are generated without requiring a power-hungry A/D converter. A prototype chip has been fabricated in the 0.5/spl mu/m AMI CMOS process. Experimental results are reported showing the performance of the circuit as a chemical sensor.
Analysis and Distribution of Vitamin E in Vegetable Oils and Foods (2023)

This chapter addresses the nomenclature, terminology, and definitions of vitamin E or compounds exhibiting vitamin E activity that vary with the audience. A nomenclature policy for vitamins and related compounds has been established by AIN and published in the Journal of Nutrition based on the nomenclature naming procedures developed by the International Union of Nutrition Sciences Committee on Nomenclature. This nomenclature policy is consistent with the Recommendations of the Commission on Biochemical Nomenclature. The Association of Official Analytical Chemists states that the "term vitamin E should be used as generic descriptor for all tocol- and tocotrienol derivatives" that exhibit vitamin E activity. The extraction process is a very critical step in the analysis. The extracting agents include ether, hexane, acetone, chloroform, ethanol, propanol, and, in some cases, combinations of solvents.
Agent-driven online business in virtual communities (2000)

As virtual communities and electronic commerce are merging into each other, following users' wishes and companies' needs, electronic commerce is, at the same time, starting to support the whole purchasing process, with agent technology adding efficiency and flexibility. We discuss the integration of a multi-agent market framework (CASBA) in a virtual community (VR-SHOP), which uses 3D graphical representations of the participants (avatars) to raise user acceptance and usability by providing a more natural interaction with the medium of interest. As an agent-driven online marketplace, the CASBA system provides an open, automated and flexible platform for electronic commerce. It supports parallel negotiations, following user-specified utility functions and rule-based strategies, and various kinds of auctions.
Structural dependence of the optical properties of narrow bandgap semiconductors with orthogonal donor–acceptor geometries (2013)

We discuss donor–acceptor conjugated polymers where the acceptor moieties are orthogonal to the donor-based backbone direction through the synthesis and study of a new class of materials (including six oligomers and three polymers) based on 4H-cyclopentadithiophene (CPDT) with an imine functionality introduced at the CPDT bridgehead position. Absorption spectroscopy provides information on the influence of structure on the optical properties. We paid special attention to the energies and oscillator strengths of the low-energy transitions and how they correlate with chain length. When the orthogonally conjugated materials are compared to a more traditional polymer, where the donor and acceptor fragments are in series along the backbone direction, fundamental differences in the optical properties are observed. Quantum-mechanical studies of the geometric structure, electronic structure, and excited-state vertical transitions using density functional theory unravel the interplay of structural design and resulting optoelectronic properties. Our findings underline that the magnitude and orientation relative to the backbone long axis of the transition dipole moment is key in designing narrow optical-gap materials with large absorption cross-sections and oscillator strengths.
Human X chromosome inactivation and reactivation: implications for cell reprogramming and disease (2017)

X-chromosome inactivation (XCI) is an exemplar of epigenetic regulation that is set up as pluripotent cells differentiate. Once established, XCI is stably propagated, but can be reversed <i>in vivo</i> or by pluripotent reprogramming <i>in vitro</i> Although reprogramming provides a useful model for inactive X (Xi) reactivation in mouse, the relative instability and heterogeneity of human embryonic stem (ES) cells and induced pluripotent stem cells hampers comparable progress in human. Here we review studies aimed at reactivating the human Xi using different reprogramming strategies. We outline our recent results using mouse ES cells to reprogramme female human fibroblasts by cell-cell fusion. We show that pluripotent reprogramming induces widespread and rapid chromatin remodelling in which the human Xi loses <i>XIST</i> and H3K27m3 enrichment and selected Xi genes become reactivated, ahead of mitotic division. Using RNA sequencing to map the extent of human Xi reactivation, and chromatin-modifying drugs to potentiate reactivation, we outline how this approach could be used to better design strategies to re-express human X-linked loci. As cell fusion induces the expression of human pluripotency genes that represent both the 'primed' and 'naive' states, this approach may also offer a fresh opportunity to segregate human pluripotent states with distinct Xi expression profiles, using single-cell-based approaches.This article is part of the themed issue 'X-chromosome inactivation: a tribute to Mary Lyon'.
Machine Vision Sorting and Inspection in Commercial Automatic Dishwashing (1993)

Mechanical Engineering
High UV sensitivity of SiON film and its application to center wavelength trimming of microring resonator filter (2005)

We demonstrated a vertically coupled microring resonator (VCMRR) filter as an Add/Drop wavelength filter. However, the accuracy of center wavelength was not sufficiently high for dense wavelength division multiplexing (DWDM) systems. Thus, a UV trimming technique using a Sin (n=2.01 at λ=1.55μm) ring core was previously developed. Although a wide center wavelength trimming range of -12.1 nm and the long-term stability of center wavelength were realized, the core size required for single-mode propagation was too small for fabrication using a photolithography process. Therefore in this study, we introduced SiON as the microring core to relax the single-mode condition of core size. We discovered a large UV sensitivity of SiON film formed by a PECVD method, and a wide range UV trimming of microring resonator of -10.5 nm was demonstrated using this phenomenon.
Kinetic studies in heterogeneous photocatalysis. 2. Titania-mediated degradation of 4-chlorophenol alone and in a three-component mixture of 4-chlorophenol, 2,4-dichlorophenol, and 2,4,5-trichlorophenol in air-equilibrated aqueous media (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTKinetic studies in heterogeneous photocatalysis. 2. Titania-mediated degradation of 4-chlorophenol alone and in a three-component mixture of 4-chlorophenol, 2,4-dichlorophenol, and 2,4,5-trichlorophenol in air-equilibrated aqueous mediaHussain Al-Ekabi, Nick Serpone, Ezio Pelizzetti, Claudio Minero, Marye Anne Fox, and R. Barton DraperCite this: Langmuir 1989, 5, 1, 250–255Publication Date (Print):January 1, 1989Publication History Published online1 May 2002Published inissue 1 January 1989https://pubs.acs.org/doi/10.1021/la00085a048https://doi.org/10.1021/la00085a048research-articleACS PublicationsRequest reuse permissionsArticle Views1066Altmetric-Citations251LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Effects of leukotriene receptor antagonist on chronic obstructive [correction of obstractive] pulmonary disease induced pulmonary hypertension. (2003)

Zafirlukast can reduce mPAP, pulmonary vascular resistance (PVR) and does not affect the ambulatory blood pressure monitoring (ABPM) and oxygenation in cases of chronic cor pulmonale at acute exacerbation stage. Zafirlukast may play a role as an alternative to decrease PAP in COPD patients.
Sprouty2 Inhibits the Ras/MAP Kinase Pathway by Inhibiting the Activation of Raf (2002)

Several genetic studies in Drosophila have shown that the dSprouty (dSpry) protein inhibits the Ras/mitogen-activated protein (MAP) kinase pathway induced by various activated receptor tyrosine kinase receptors, most notably those of the epidermal growth factor receptor (EGFR) and fibroblast growth factor receptor (FGFR). Currently, the mode of action of dSpry is unknown, and the point of inhibition remains controversial. There are at least four mammalian Spry isoforms that have been shown to co-express preferentially with FGFRs as compared with EGFRs. In this study, we investigated the effects of the various mammalian Spry isoforms on the Ras/MAP kinase pathway in cells overexpressing constitutively active FGFR1. hSpry2 was significantly more potent than mSpry1 or mSpry4 in inhibiting the Ras/MAP kinase pathway. Additional experiments indicated that full-length hSpry2 was required for its full potency. hSpry2 had no inhibitory effect on either the JNK or the p38 pathway and displayed no inhibition of FRS2 phosphorylation, Akt activation, and Ras activation. Constitutively active mutants of Ras, Raf, and Mek were employed to locate the prospective point of inhibition of hSpry2 downstream of activated Ras. Results from this study indicated that hSpry2 exerted its inhibitory effect at the level of Raf, which was verified in a Raf activation assay in an FGF signaling context.
Preparation of a MoS<sub>2</sub>/carbon nanotube composite as an electrode material for high-performance supercapacitors (2018)

MoS<sub>2</sub> and MoS<sub>2</sub>/carbon allotrope (MoS<sub>2</sub>/C) composites for use as anodes in supercapacitors were prepared <i>via</i> a facile hydrothermal method. In this study, we report the effects of various carbon-based materials (2D graphene nanosheet (GNS), 1D carbon nanotube (CNT), and 0D nano carbon (NC)) on the electrochemical performances. Among all nanocomposites studied, MoS<sub>2</sub>/CNT exhibited the best electrochemical performance. Specifically, the MoS<sub>2</sub>/CNT composite exhibits remarkable performances with a high specific capacitance of 402 F g<sup>-1</sup> at a current density of 1 A g<sup>-1</sup> and an outstanding cycling stability with 81.9% capacitance retention after 10 000 continuous charge-discharge cycles at a high current density of 1 A g<sup>-1</sup>, making it adaptive for high-performance supercapacitors. The superiority of MoS<sub>2</sub>/CNT was investigated by field emission scanning electron microscopy and transmission electron microscopy, which showed that MoS<sub>2</sub> nanosheets were uniformly loaded into the three-dimensional interconnected network of nanotubes, providing an excellent three dimensional charge transfer network and electrolyte diffusion channels while effectively buffering the collapse and aggregation of active materials during charge-discharge processes. Overall, the MoS<sub>2</sub>/CNT nanocomposite synthesized by a simple hydrothermal process presents a new and promising candidate for high-performance anodes for supercapacitors.
Effect of Time on the Remineralisation of Enamel by Synthetic Saliva after Citric Acid Erosion (2001)

The aim of this in vitro study was to determine the influence of remineralisation time on rehardening of surface-softened enamel after citric acid erosion. Seven groups of 13 samples of human enamel were eroded in 0.3% citric acid at pH 3.2 for 2 h followed by profilometric measurements. Individual groups of specimens were placed in artificial saliva for 1, 2, 4, 6, 9 or 24 h. A control group was placed in isotonic saline for 24 h. After new profilometric measurements samples were ultrasonicated stepwise up to 480 s with profilometric measurements performed at 5, 30, 120, 240 and 480 s to measure the depth of surface softening. The control group had a softened surface layer of mean thickness 2.9 microm. Mineral deposition was seen at all remineralisation times by scanning electron microscopy. Exposure to artificial saliva for 1, 2 or 4 h produced a partial rehardening of the softened enamel; the additional surface losses produced by ultrasonication were lower and time delayed compared to the control group. Specimens remineralised for 6, 9 and 24 h showed little evidence of surface loss after ultrasonication. The data suggest that a complete rehardening of the softened enamel in vitro is reached after a remineralisation time of 6 h. These data are of clinical relevance to tooth wear. However, there is a need for studies in situ of enamel demineralisation and remineralisation.
Optimizing walking controllers (2009)

This paper describes a method for optimizing the parameters of a physics-based controller for full-body, 3D walking. A modified version of the SIMBICON controller [Yin et al. 2007] is optimized for characters of varying body shape, walking speed and step length. The objective function includes terms for power minimization, angular momentum minimization, and minimal head motion, among others. Together these terms produce a number of important features of natural walking, including active toe-off, near-passive knee swing, and leg extension during swing. We explain the specific form of our objective criteria, and show the importance of each term to walking style. We demonstrate optimized controllers for walking with different speeds, variation in body shape, and in ground slope.
[Sigg's sclerosing therapy]. (1991)

This type of treatment involves the use of a large diameter needle (1.2 mm) in order to avoid the risk of intra-arterial injection. A very supple all-glass 2 cc syringe enables any extraluminal position of the needle to be felt and thus prevents paravascular injection. The iodinated solution used (Variglobine), at different concentrations, is injected with the leg raised. The volume injected should not exceed one cc per injection. A case involving extensive lesions may require up to ten injections per leg and per session. Strong compression obtained using reduced elasticity elastic bandages is then worn during the day. The duration of such compression varies between two and four weeks. An elastic stocking is then worn for the same length of time. Any possible intra-varicose retention products are removed by incision under local anesthesia. The risk of cutaneous hyperpigmentation is greatly reduced in this way.
Microchannel deformations due to solvent-induced PDMS swelling (2010)

The compatibility of polydimethylsiloxane (PDMS) channels with certain solvents is a well known problem of soft lithography techniques, in particular when it leads to the swelling of the PDMS blocks. However, little is known about the modification of microchannel geometries when they are subjected to swelling solvents. Here, we experimentally measure the deformations of the roof of PDMS microchannels due to such solvents. The dynamics of impregnation of the solvents in PDMS and its relation to volume dilation are first addressed in a model experiment, allowing the precise measurement of the diffusion coefficients of oils in PDMS. When Hexadecane, a swelling solvent, fills a microchannel 1 mm in width and 50 μm in height, we measure that the channel roof bends inwards and takes a parabolic shape with a maximum deformation of 7 μm. The amplitude of the subsidence is found to increase with the channel width, reaching 28 μm for a 2 mm wide test section. On the other hand, perfluorinated oils do not swell the PDMS and the microchannel geometry is not affected by the presence of perfluorodecalin. Finally, we observe that the trajectories of droplets flowing in this microchannel are strongly affected by the deformations: drops carried by swelling oils are pushed towards the edges of the channel while those carried by non-swelling oils remain in the channel center.
Catalytic asymmetric synthesis of either enantiomer of physostigmine. Formation of quaternary carbon centers with high enantioselection by intramolecular Heck reactions of (Z)-2-butenanilides (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCatalytic asymmetric synthesis of either enantiomer of physostigmine. Formation of quaternary carbon centers with high enantioselection by intramolecular Heck reactions of (Z)-2-butenanilidesAtsuyuki Ashimori, Takaharu Matsuura, Larry E. Overman, and Daniel J. PoonCite this: J. Org. Chem. 1993, 58, 25, 6949–6951Publication Date (Print):December 1, 1993Publication History Published online1 May 2002Published inissue 1 December 1993https://pubs.acs.org/doi/10.1021/jo00077a005https://doi.org/10.1021/jo00077a005research-articleACS PublicationsRequest reuse permissionsArticle Views1665Altmetric-Citations154LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Physicochemical Determinants of Multiwalled Carbon Nanotube Bacterial Cytotoxicity (2008)

Rational modification of carbon nanotubes (CNTs) to isolate their specific physical and chemical properties will inform a mechanistic understanding of observed CNT toxicity in bacterial systems. The present study compares the toxicity of commercially obtained multiwalled carbon nanotubes (MWNTs) before and after physicochemical modification via common purification and functionalization routes, including dry oxidation, acid treatment functionalization, and annealing. Experimental results support a correlation between bacterial cytotoxicity and physicochemical properties that enhance MWNT-cell contact opportunities. For example, we observe higher toxicity when the nanotubes are uncapped, debundled, short, and dispersed in solution. These conclusions demonstrate that physicochemical modifications of MWNTs alter their cytotoxicity in bacterial systems and underline the need for careful documentation of physical and chemical characteristics when reporting the toxicity of carbon-based nanomaterials.
Transesterification Reaction of Tetraethoxysilane and Butyl Alcohols (1988)

Abstract Tetraethoxysilane was treated with Amberlyst 15 cation-exchange resin in the presence of butyl alcohols. On treating the mixture of tetraethoxysilane and 1-butanol, the transesterification took place in which butoxyl groups were substituted for ethoxyl groups in tetraethoxysilane. The degree of the transesterification depended on the molar ratio of tetraethoxysilane to 1-butanol of the mixture. The distribution of alkoxysilane species present in the tetraethoxysilane–1-butanol solution was compared with the tetrabutoxysilane–ethanol solution, and it was found that the degree of the transesterification depended on the ratio of numbers of alkyl groups in tetraalkoxysilane and alcohol used. The time required for equilibrium in the distribution of alkoxysilane species in the solution was different with the variety of butyl alcohols used, suggesting the presence of steric effect of butyl alcohols on this reaction.
Rapid Expression of Human Immunodeficiency Virus following Activation of Latently Infected Cells (2006)

The host cell activation state impacts the nature of human immunodeficiency virus infection. Activated cells facilitate productive infections; quiescent cells enable the virus to enter a latent state, the major obstacle to viral clearance. We wanted to understand how these differences affected viral gene expression. In quiescent cells activated prior to infection, viral RNA was seen 12 h postinfection; when cells were stimulated postinfection, viral RNA was not seen until 36 h postinfection. Up-regulation of viral RNA in latently infected cells occurred within 2 h poststimulation. This hierarchy also held true for viral protein production. These results may explain the rapid reemergence of viremia following termination of therapy.