gebhart/patrepeval huggingface dataset:
A Session Initiation Protocol (SIP) Load-Control Event Package (2014)

This specification defines a load-control event package for the
Session Initiation Protocol (SIP). It allows SIP entities to
distribute load-filtering policies to other SIP entities in the
network. The load-filtering policies contain rules to throttle calls
from a specific user or based on their source or destination domain,
telephone number prefix. The mechanism helps to prevent signaling
overload and complements feedback-based SIP overload control efforts.
Optimum loudspeaker spacing for robust crosstalk cancellation (2002)

Crosstalk cancellation is a signal processing technique whereby two (or more) loudspeakers are used to deliver desired signals exactly at the listener's ears. Such a system is useful for 3D audio applications, and removes the requirement for the listener to wear headphones. However, crosstalk cancelers are notoriously non-robust to slight movements in head position, and there currently exists no clear method for determining the best loudspeaker placement in a given situation. We propose a robustness measure to evaluate the performance of crosstalk cancelers as a function of loudspeaker spacing. Based on this analysis we conclude that certain loudspeaker spacings give far better robustness performance, and provide a simple empirically-derived equation for determining the optimum loudspeaker spacing in a given situation.
Microbial treatment of sulfur-contaminated industrial wastes (2013)

The present study evaluated the microbial removal of sulfur from a solid industrial waste in liquid culture under laboratory conditions. The study involved the use of two bacteria Acidithiobacillus ferrooxidans ATCC 53987 and Acidithiobacillus thiooxidans AZCT-M125-5 isolated from a Mexican soil. Experimentation for industrial waste biotreatment was done in liquid culture using 125-mL Erlenmeyer flasks containing 30 mL Starkey modified culture medium and incubated at 30°C during 7 days. The industrial waste was added at different pulp densities (8.25-100% w/v) corresponding to different sulfur contents from 0.7 to 8.63% (w/w). Sulfur-oxidizing activity of the strain AZCT-M125-5 produced 281 and 262 mg/g of sulfate and a sulfur removal of 60% and 45.7% when the pulp density was set at 8.25 and 16.5% (w/v), respectively. In comparison, the strain A. ferrooxidans ATCC 53987 showed a lower sulfur-oxidizing activity with a sulfate production of 25.6 and 12.7 mg/g and a sulfur removal of 6% and 2.5% at the same pulp densities, respectively. Microbial growth was limited by pulp densities higher than 25% (w/v) of industrial waste with minimal sulfur-oxidizing activity and sulfur removal. The rate of sulfur removal for Acidithiobacillus thioxidans AZCT-M125-5 and Acidithiobacillus ferrooxidans ATCC 53987 was 0.185 and 0.0159 mg S g(-1) h(-1) with a pulp density of 16.5% (w/v), respectively. This study demonstrated that Acidithiobacillus thiooxidans AZCT-M125-5 possesses a high sulfur-oxidizing activity, even at high sulfur concentration, which allows the treatment of hazardous materials.
Quantum Dot Composite Radiation Detectors (2011)

Inspired by experimental high-energy physics experiments, the first radiation detectors in positron emission tomography (PET), computer tomography (CT), and gamma-cameras were built of scintillators combined with vacuum phototubes (e.g., photomultipliers, photodiodes). Fifty years later, the scintillators/photomultiplier approach has matured, but still has intrinsic limitations. Vacuum phototubes are relatively bulky. Photomultipliers require high voltage (e.g., 0.5-2.5 kV). Vacuum phototubes are delicate because of fragile glass or quartz windows (a requisite for light to enter the vacuum tube) and fine-gap electrode structures (e.g., dynodes, grid and anode) suspended within the vacuum. Photocathodes can be irreversibly damaged if the photomultiplier is powered under normal lighting conditions. Most types of vacuum photodetectors are sensitive to external magnetic fields and therefore require magnetic shielding for certain environments (e.g., inside Magnetic Resonance Imaging systems). Vacuum phototube aging is often another challenge, because over time, vacuum inside photomultipliers tube degrades, resulting in performance degradation (e.g., increasing noise). Today, the scintillator/vacuum phototube combination is being replaced by the scintillator/solid state photomultiplier combination (e.g., Multi-Pixel Photon Counter by Hamamatsu or Silicon Photomultipliers by SensL). Solid state photomultipliers address some of the limitations of vacuum phototubes. For example, solid state photodetectors have small size, do not require high voltage, are more robust mechanically, and are compatible with strong magnetic fields. However, they bring new challenges: higher noise and very high sensitivity to temperature and supply voltage variations. Even more importantly, solid state photodetectors do not address main challenges in radiation detection (e.g., the need for better sensitivity and better energy and spatial resolution), because the approach still depends on the same scintillators and thus involves a multistep process for converting radiation to signal: using scintillators to convert radiation to visible light, then transporting the light into the photodetector, which finally converts light into electrical signals. A better alternative is the use of direct-conversion radiation detectors.
Interatrial Conduction Correlates with Optimal Atrioventricular Timing in Cardiac Resynchronization Therapy Devices (2011)

IACT is a critical determinant of the optimal AV for CRT programming. Heart rate-dependent AV shortening may not be appropriate for CRT patients during atrial pacing.
Artist-Directed Inverse-Kinematics Using Radial Basis Function Interpolation (2001)

One of the most common tasks in computer animation is inverse-kinematics, or determining a joint configuration required to place a particular part of an articulated character at a particular location in global space. Inverse-kinematics is required at design-time to assist artists using commercial 3D animation packages, for motion capture analysis, and for run-time applications such as games. We present an efficient inverse-kinematics methodology based on the interpolation of example motions and positions. The technique is demonstrated on a number of inverse-kinematics positioning tasks for a human figure. In addition to simple positioning tasks, the method provides complete motion sequences that satisfy an inverse-kinematic goal. The interpolation at the heart of the algorithm allows an artist's influence to play a major role in ensuring that the system always generates plausible results. Due to the lightweight nature of the algorithm, we can position a character at extremely high frame rates, making the technique useful for time-critical run-time applications such as games.
Bifurcations: Focal Points of Particle Adhesion in Microvascular Networks (2011)

Bifurcations are the focal points of particle adhesion in microvascular networks. Changing flow patterns and morphology near bifurcations are the primary factors controlling the preferential adhesion of functionalized particles in microvascular networks. SMNs provide an in vitro framework for understanding particle adhesion.
A comparative study of 16 tractography algorithms for the corticospinal tract: reproducibility and subject-specificity. (2014)

We present a comparative study of fiber tractography algorithms on a test-retest dataset. This work and the conclusions it leads to will guide the choice of a tracking algorithm for applications ranging from surgical planning to group-based connectivity analysis. We evaluate 16 different tracking algorithms, using their either freely available implementations or in house software. We compare their ability to produce reproducible tracking, as well as to capture subject-specific tract geometry.
Dynamic Intraoperative Prostate Brachytherapy Using 3D TRUS Guidance with Robot Assistance (2005)

This paper describes a system for dynamic intraoperative prostate brachytherapy using 3D ultrasound guidance with robotic assistance. The system consists of 3D TRUS imaging, a robot and software for prostate segmentation, intraoperative planning, oblique needle segmentation and tracking, seed segmentation, and 3D dose planning. The robot and 3D TRUS coordinate systems are unified through robot and image calibrations. In 3D ultrasound images, the prostate is segmented using the discrete dynamic contour method, and optimal implantation plan is performed using geometric optimization followed by simulated annealing. The inserted needles are segmented and tracked using grey-level change in near real-time, and seed segmentation is performed using 3D line segment patterns. Needle placement accuracy of the robot at the "patient" skin was 0.15mm± 0.06mm, and needle angulation error was 0.07°. Needle targeting accuracy was 0.79mm±0.32mm.
Long-wavelength infrared doping-spike PtSi detector (1993)

By incorporating a 1-nm-thick p<SUP>+</SUP> doping spike at the PtSi/Si interface, we have successfully demonstrated extended cutoff wavelengths of PtSi Schottky infrared detectors in the long wavelength infrared (LWIR) regime for the first time. The extended cutoff wavelengths resulted from the combined effects of an increased electric field near the silicide/Si interface due to the p<SUP>+</SUP> doping spike and the Schottky image force. The p<SUP>+</SUP> doping spikes were grown by molecular beam epitaxy at 450 degree(s)C using elemental boron as the dopant source, with doping concentrations ranging from 5 X 10<SUP>19</SUP> to 2 X 10<SUP>20</SUP> cm<SUP>-3</SUP>. Transmission electron microscopy indicated good crystalline quality of the doping spikes. The cutoff wavelengths were shown to increase with increasing doping concentrations of the p<SUP>+</SUP> spikes. Thermionic emission dark current characteristics were observed and photoresponse in the LWIR regime was demonstrated.
Polyanthraquinone‐Based Organic Cathode for High‐Performance Rechargeable Magnesium‐Ion Batteries (2016)

Two anthraquinone-based polymers aiming at improving the capacity and voltage of magnesium ion batteries, were synthesized and characterized. The excellent battery cycling performance was demonstrated with the electrolyte consisting of magnesium bis(hexamethyldisilazide) and magnesium chloride. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Human conglutinin-like protein (1985)

The presence in human plasma of a molecule homologous to bovine conglutinin is indicated by the results of biological and immunochemical analysis. The human conglutinin-like protein shows calcium-dependent binding to complement-treated solid phase IgG and immunological cross-reaction with chicken anti-bovine conglutinin. The binding of the human protein to complement-treated IgG was inhibited by N-acetyl-D-glucosamine but not by other sugars. Analysis by SDS-PAGE and Western blotting showed reaction of anti-conglutinin with molecules of similar mobility to the monomer and hexamer of bovine conglutinin.
Efficient Complete Oxidation of Acetaldehyde into CO<sub>2</sub> over CuBi<sub>2</sub>O<sub>4</sub>/WO<sub>3</sub> Composite Photocatalyst under Visible and UV Light Irradiation (2007)

A highly efficient and visible light responsive photocatalyst was developed by combining the p-type semiconductor CuBi2O4 and the n-type semiconductor WO3. CuBi2O4/WO3 showed higher reactivity than typical TiO2-based photocatalysts for the complete oxidation of acetaldehyde into CO2 under both UV and visible light. From photoelectrochemical measurements, the reaction mechanism is explained based on the model of the p−n photochemical diode for reductivity/oxdizability improvement.
Binding properties of monoclonal antibodies recognizing external epitopes of the human MDR1 P‐glycoprotein (1993)

Monoclonal antibodies (MAbs) recognizing external epitopes of the human MDR1 P-glycoprotein have been used both for the detection of multidrug-resistant cells and as specific inhibitors of P-glycoprotein-mediated multidrug resistance. Using a panel of recently developed transfected or transgenic cell lines containing variants of the human MDR1 and MDR3 P-glycoproteins, we have compared the specificity and binding properties of the previously isolated MAbs MRK16, HYB-241, UIC2 and 4E3, and of the newly isolated MAb 7G4. The removal of 1, 2 or all 3 of the N-glycosylation sites present in the first extracellular loop of MDR1 P-glycoprotein did not significantly affect the binding of these MAbs. In contrast, 20 amino acid deletion in the first extracellular loop of MDR1 P-glycoprotein completely abolished binding of UIC2, whereas the binding of all other MAbs was hardly affected. None of the MAbs tested bound detectably to cell lines containing a high level of the human MDR3 P-glycoprotein. The differences in the binding specificity between UIC2 and the other tested antibodies parallel the reported functional differences in the ability of these antibodies to inhibit P-glycoprotein-mediated drug efflux.
Architecting the Lumeta firewall analyzer (2001)

Practically every corporation that is connected to the Internet has at least one firewall, and often many more. However, the protection that these firewalls provide is only as good as the policy they are configured to implement. Therefore, testing, auditing, or reverse-engineering existing firewall configurations should be important components of every corporation's network security practice. Unfortunately, this is easier said than done. Firewall configuration files are written in notoriously hard to read languages, using vendor-specific GUIs. A tool that is sorely missing in the arsenal of firewall administrators and auditors is one that will allow them to analyze the policy on a firewall.

The first passive, analytical, firewall analysis system was the Fang prototype system [MWZ00]. This was the starting point for the new Lumeta Firewall Analyzer (LFA) system. LFA improves upon Fang in many ways. The most significant improvements are that human interaction is limited to providing the firewall configuration, and that LFA automatically issues the interesting queries and displays the outputs of all of them, in a way that highlights the risks without cluttering the high-level view. This solves a major usability problem we found with Fang, namely, that users do not know which queries to issue.

The input to the LFA consists of the firewall's routing table, and the firewall's configuration files. The LFA parses these various low-level, vendor-specific, files, and simulates the firewall's behavior against all the packets it could possibly receive. The simulation is done completely offline, without sending any packets. The administrator gets a comprehensive report showingwhich types of traffic the firewall allows to enter from the Internet into the customer's intranet and which types of traffic are allowed out of the intranet. The LFA's report is presented as a set of explicit web pages, which are rich with links and cross references to further detail (allowing for easy drill-down). This paper describes the design and architecture of the LFA.
Radio Frequency Beamforming Based on a Complex Domain Frontend (2015)

The state-of-the-art phased array-based digital beamforming systems suffer from disadvantages of high power consumption, high cost, and system complexity due to the massive use of transmitter/receiver (T/R) modules and high-speed digital and digital–analog mixed devices. In this paper, we point out that by proposing a new concept “complex domain” radio frequency (RF) frontend, the relatively slowly changed waveform delay information required to accomplish adaptive beamforming can be separated from wideband RF signals, based on which a self-contained beamforming system can be implemented with a low-speed baseband. By introducing vector RF multipliers in the proposed frontend, the amplitude and phase of RF signals can be simultaneously controlled by the real and imaginary parts of complex numbers, such that beamforming algorithms derived in complex domain can be directly applied without any form of transformation. By doing so, the massive use of conventional T/R modules and high-speed baseband devices can be avoided. Theoretical analysis and experimental demonstration based on commercial components have validated the proposed approach. Our method is able to significantly simplify the realization and decrease the cost of wideband digital beamforming systems, and can be widely used in low cost, power efficient beamforming applications.
COMMUNICATION: IMPROVEMENT OF THE NATURAL FLAME-RESISTANCE OF WOOL. PART I: METAL-COMPLEX APPLICATIONS (1974)

Negatively charged titanium and zirconium complexes with α-hydroxy carboxylic acids and fluorides can be exhausted on the positively charged wool fibre in acid conditions, the result being a significant improvement in the natural flame-resistance of wool that is fast to washing and dry-cleaning. The complexes with carboxylic acids are exhausted on the wool fibre at the boil, whereas the fluoride complexes can be effectively exhausted at lower temperatures. The fluoride complexes can also be applied by a pad-batch-rinse-dry technique. Titanium complexes are more effective than the zirconium ones, probably because of better penetration of the fibre with the smaller titanium complexes. However, titanium complexes cause yellowing of wool, which increases with light exposure. Zirconium complexes do not affect the shade of wool and are fast to light.
Serum and urinary biomarker signatures for rapid preclinical in vivo assessment of CDK inhibition as a therapeutic approach for PKD (2008)

Recent advances in understanding the molecular pathogenesis of polycystic kidney diseases (PKD) are being translated into promising treatments. Currently, a response to therapy in preclinical animal models of PKD can only be evaluated after several weeks of treatment. The availability of biomarkers for rapid efficacy assessment would greatly facilitate the drug development process. Here we applied SELDI-TOF technology to establish serum and urinary biomarker signatures associated with a rapid therapeutic response to cyclin dependent kinase (CDK) inhibitor roscovitine in the jck mouse model of PKD. A set of 74 serum and 56 urinary markers was identified in the group receiving chronic treatment over 5 weeks. This set was further screened for early efficacy biomarkers in acutely (3-5 days) treated animals with mild (26 days of age) and advanced disease (50 days of age). A third group with intermediate disease (33 days of age) received a single injection to monitor rapid changes in protein profiles within 4, 24 or 48 hours after drug administration. Multifactorial comparative analysis of the acutely treated groups identified a set of 20 urinary and 21 serum efficacy biomarkers. This biomarker signature provides a necessary tool for further assessment of CDK inhibitors as therapeutic agents for PKD.
On-the-fly resolve trace minimization (2007)

The ability of modern SAT solvers to produce proofs of un-satisfiability for Boolean formulas has become a powerful tool for EDA applications. Proofs are generated from a resolve trace that captures information about the creation of all conflict clauses. Due to their sizes, resolve traces are kept in files. The sizes of these files makes the use of proofs of un-satisfiability impractical for industrial tools. Although only a small part of the resolve trace is eventually used, until now it was not known how to filter out unnecessary information.
Novel Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase with Anti-malarial Activity in the Mouse Model* (2010)

Plasmodium falciparum, the causative agent of the most deadly form of human malaria, is unable to salvage pyrimidines and must rely on de novo biosynthesis for survival. Dihydroorotate dehydrogenase (DHODH) catalyzes the rate-limiting step in the pyrimidine biosynthetic pathway and represents a potential target for anti-malarial therapy. A high throughput screen and subsequent medicinal chemistry program identified a series of N-alkyl-5-(1H-benzimidazol-1-yl)thiophene-2-carboxamides with low nanomolar in vitro potency against DHODH from P. falciparum, P. vivax, and P. berghei. The compounds were selective for the parasite enzymes over human DHODH, and x-ray structural data on the analog Genz-667348, demonstrated that species selectivity could be attributed to amino acid differences in the inhibitor-binding site. Compounds from this series demonstrated in vitro potency against the 3D7 and Dd2 strains of P. falciparum, good tolerability and oral exposure in the mouse, and ED(50) values in the 4-day murine P. berghei efficacy model of 13-21 mg/kg/day with oral twice-daily dosing. In particular, treatment with Genz-667348 at 100 mg/kg/day resulted in sterile cure. Two recent analogs of Genz-667348 are currently undergoing pilot toxicity testing to determine suitability as clinical development candidates.
Rechargeable calcium phosphate orthodontic cement with sustained ion release and re-release (2016)

White spot lesions (WSL) due to enamel demineralization are major complications for orthodontic treatments. Calcium phosphate (CaP) dental resins with Ca and P ion releases are promising for remineralization. However, previous Ca and P releases lasted for only weeks. Experimental orthodontic cements were developed using pyromellitic glycerol dimethacrylate (PMGDM) and ethoxylated bisphenol A dimethacrylate (EBPADMA) at mass ratio of 1:1 (PE); and PE plus 10% of 2-hydroxyethyl methacrylate (HEMA) and 5% of bisphenol A glycidyl dimethacrylate (BisGMA) (PEHB). Particles of amorphous calcium phosphate (ACP) were incorporated into PE and PEHB at 40% filler level. Specimens were tested for bracket-enamel shear bond strength, water sorption, CaP release, and ion recharge and re-release. PEHB+40ACP had higher bracket-enamel bond strength and ion release and rechargeability than PE+40ACP. ACP incorporation into the novel orthodontic cement did not adversely affect the bracket-enamel bond strength. Ion release and re-release from the novel ACP orthodontic cement indicated favorable release and re-release patterns. The recharged orthodontic cement could release CaP ions continuously for four weeks without further recharge. Novel rechargeable orthodontic cement containing ACP was developed with a high bracket-enamel bond strength and the ability to be repeatedly recharged to maintain long-term high levels of CaP ion releases.
Photosensitive Pentacene Precursor: Synthesis, Photothermal Patterning, and Application in Thin‐Film Transistors (2003)

The Diels–Alder adduct of pentacene and N ‐sulfinylmethacrylamide is used as a soluble, photopolymerizable precursor of pentacene for fabrication of patterned thin‐film transitors. The Figure shows the optical micrograph of patterned pentacene derived from the exposure of this adduct to UV radiation, followed by development in methanol and annealing at 200 °C for 90 s.