gebhart/patrepeval huggingface dataset:
Tightly-coupled robust vision aided inertial navigation algorithm for augmented reality using monocular camera and IMU (2011)

Odometry component of a camera tracking system for augmented reality applications is described. The system uses a MEMS-type inertial measurement unit (IMU) with 3-axis gyroscopes and accelerometers and a monocular camera to accurately and robustly track the camera motion in 6 degrees of freedom (with correct scale) in arbitrary indoor or outdoor scenes. Tight coupling of IMU and camera is achieved by an error-state extended Kalman filter (EKF) which performs sensor fusion for inertial navigation at a deep level such that each visually tracked feature contributes as an individual measurement as opposed to the more traditional approaches where camera pose estimates are first extracted by means of feature tracking and then used as measurement updates in a filter framework. Robustness, on the other hand, is achieved by using a geometric hypothesize-and-test architecture based on the five-point relative pose estimation method, rather than a Mahalanobis distance type gating mechanism derived from the Kalman filter state prediction, to select the inlier tracks and remove outliers from the raw feature point matches which would otherwise corrupt the filter since tracks are directly used as measurements.
Immunological Technique for Measuring Insect Contamination of Grain (1992)

Journal Article Immunological Technique for Measuring Insect Contamination of Grain Get access Frank A. Quinn, Frank A. Quinn Department of Chemistry and Biochemistry, University of Texas at Austin, Austin, Texas 78712 Search for other works by this author on: Oxford Academic PubMed Google Scholar Wendell Burkholder, Wendell Burkholder Department of Chemistry and Biochemistry, University of Texas at Austin, Austin, Texas 78712 Search for other works by this author on: Oxford Academic PubMed Google Scholar Barrie G. Kitto Barrie G. Kitto Department of Chemistry and Biochemistry, University of Texas at Austin, Austin, Texas 78712 Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Economic Entomology, Volume 85, Issue 4, 1 August 1992, Pages 1463–1470, https://doi.org/10.1093/jee/85.4.1463 Published: 01 August 1992 Article history Received: 13 November 1990 Accepted: 25 March 1992 Published: 01 August 1992
Planning for camera-guided robotic radiosurgery (1998)

Radiosurgery is a treatment for brain tumours and other lesions which employs a moving beam of photon radiation. In robotic radiosurgery, the radiation source is moved by a six degree-of-freedom robotic arm. A treatment planning system for robotic radiosurgery was developed. This planning system combines collision avoidance techniques and geometric algorithms for finding appropriate robot paths and beam activation profiles. The following design goals characterize our application: 1) ability to generate conformal 3D dose distributions; 2) transparency of the planning process; and 3) full use of the motion flexibility provided by the robotic arm. The new planning system is in clinical use in several leading medical institutions. Results obtained from the studies suggest that highly conformal distributions can be generated in a very effective way.
Modular AWG-based Interconnection for Large-Scale Data Center Networks (2016)

Along with the recent surge in scale expansion of data centers, the interconnection scheme is facing a grave challenge. A huge amount of cables between the switches make the system maintenance and heat dissipation extremely difficult. A promising solution to this problem is using the arrayed waveguide grating (AWG), which can provide a set of wavelength links between its inputs and outputs. However, the scalability of the AWG-based interconnection scheme is restricted by the coherent crosstalk and the wavelength granularity of AWGs. In this paper, we propose a generic modular AWG-based interconnection scheme with scalable wavelength granularity for mega data centers. We first devise a matrix-based method to decompose the AWG into a three-stage network of smaller AWGs, while preserving the nonblocking wavelength routing property of the AWGs. We then introduce the concept of wavelength independency based on the partitioning of the optical connections, such that modular AWGs in the network can reuse the same wavelength set with smaller granularity. We show that the proposed modular AWG-based interconnection network can simplify the cabling complexity of data center networks, while preserving the same function and bandwidth as the original data center network.
Arginines of the RGG box regulate FMRP association with polyribosomes and mRNA (2010)

Fragile X syndrome is caused by the loss of expression of the fragile X mental retardation protein, FMRP. FMRP is an RNA-binding protein that is highly expressed in neurons and undergoes multiple post-translational modifications including methylation on arginine. FMRP is methylated on the high-affinity RNA-binding motif, the RGG box, at positions 533, 538, 543 and 545 of murine FMRP. To identify the arginines important for FMRP function, we examined their role in polyribosome and mRNA association. We found that arginines 533 and 538 were required for normal FMRP polyribosome association whereas all four arginines played a role in RNA binding, depending on the identity of the RNA. The model G-quadruplex RNA sc1 required arginines 533 and 538 for normal association with FMRP, whereas AATYK mRNA did not. In vitro methylation of FMRP-bearing arginine substitutions inhibited sc1 binding but not AATYK binding. In addition, we found that PRMT1 co-immunoprecipitated with FMRP isolated from cells and that siRNAs directed against PRMT1 led to reduced FMRP methylation. Thus, two lines of experimentation demonstrate that PRMT1 acts on FMRP in cells. In summary, we provide evidence for the important role of the RGG box in polyribosome association. We also demonstrate for the first time that the different arginines of the RGG box are important for the binding of different RNAs. Finally, we show that PRMT1 methylates FMRP in cells, suggesting a model where methylation of the RGG box modulates either the quantity or the identity of the RNAs bound by FMRP.
Concentration cascade of leading electrolyte using bidirectional isotachophoresis (2012)

We present a novel method of creating concentration cascade of leading electrolyte (LE) in isotachophoresis (ITP) by using bidirectional ITP. ITP establishes ion-concentration shock waves between high-mobility LE and low-mobility trailing electrolyte (TE) ions. In bidirectional ITP, we set up simultaneous shock waves between anions and cations such that these waves approach each other and interact. The shock interaction causes a sudden decrease in LE concentration ahead of the focused anions and a corresponding decrease in analyte zone concentrations. This readjustment of analyte zone concentrations is accompanied by a corresponding increase in their zone lengths, in accordance to conservation laws. The method generates in situ gradient in the LE concentration, and therefore can be achieved in a single, straight channel simply by establishing the initial electrolyte chemistry. We have developed an analytical model useful in designing the process for maximum sensitivity and estimating increase in sample zone length due to shock interaction. We also illustrate the technique and evaluate its effectiveness in increasing detection sensitivity using transient simulations of species transport equations. We validated the theoretical predictions using experimental visualizations of bidirectional ITP zones for various electrolyte chemistries. Lastly, we use our technique to demonstrate a factor of 20 increase in the sensitivity of ITP-based detection of 2,4,6-trichlorophenol.
DS/SS code acquisition using a locally suboptimum rank detector (2002)

In this paper signed-rank based nonparametric detectors are used for pseudonoise (PN) code acquisition in direct sequence spread spectrum (DS/SS) systems. We first derive the locally optimum rank (LOR) detector and then propose a locally suboptimum rank (LSR) detector and a modified signed-rank (MSR) detector using approximate score functions. We compare the single-dwell scheme without the verification node using the proposed LSR and MSR detectors with that using the conventional squared-sum (SS) and modified sign (MS) detectors. From the simulation results, it is shown that the proposed LSR and MSR detectors perform better than the MS detector by about 2/spl sim/3 dB and are nearly optimum.
Selective growth of Ge nanowires by low-temperature thermal evaporation (2008)

High-quality single-crystalline Ge nanowires with electrical properties comparable to those of bulk Ge have been synthesized by vapor-liquid-solid growth using Au growth seeds on SiO(2)/Si(100) substrates and evaporation from solid Ge powder in a low-temperature process at crucible temperatures down to 700 °C. High nanowire growth rates at these low source temperatures have been identified as being due to sublimation of GeO from substantial amounts of GeO(2) on the powder. The Ge nanowire synthesis from GeO is highly selective at our substrate temperatures (420-500 °C), i.e., occurs only on Au vapor-liquid-solid growth seeds. For growth of nanowires of 10-20 µm length on Au particles, an upper bound of 0.5 nm Ge deposition was determined in areas of bare SiO(2)/Si substrate without Au nanoparticles.
Clinical Studies of Liposome-Encapsulated Doxorubicin (1994)

Initial clinical studies with doxorubicin entrapped in the bilayer of phosphatidylglycerol-rich liposomes were hindered by the avid reticuloendothelial system (RES) uptake and by drug leakage from circulating liposomes. In contrast, recent tests of a doxorubicin formulation of polyethyleneglycol-coated liposomes (Doxil) in cancer patients indicate that the drug pharmacokinetic properties are significantly altered, with a prolonged distribution half-life of approximately 2 days. Plasma fractionation studies show that nearly all the drug measured in plasma is in liposome-encapsulated form. The dose of Doxil has been escalated from 25 to 60 mg/m2. Stomatitis is the most significant toxicity, and skin toxicity, in the form of hand-foot syndrome, may complicate the repeated administration of Doxil. A number of objective antitumor responses in a variety of malignancies have been observed, indicating that Doxil is an active antitumor compound. Polyethyleneglycol-coated liposomes show a distinct advantage over previous liposome formulations directed at the RES and appear to be a promising drug delivery system for doxorubicin.
Threshold selection for UWB TOA estimation based on kurtosis analysis (2005)

In this letter, a normalized threshold selection technique for time of arrival estimation of ultra-wideband signals is proposed. It exploits the kurtosis of the received signal samples. The dependency between the kurtosis and optimal normalized threshold are investigated via simulations. The proposed technique yields efficient threshold selection, has low complexity and sampling rate requirements, and accounts both the signal to noise ratio and the statistics of individual channel realizations.
Intracavity frequency doubling of a diode-pumped external-cavity surface-emitting semiconductor laser (1999)

We present a compact, robust, solid-state blue-light (490-nm) source capable of greater than 5 mW of output in a TEM(00) mode. This device is an optically pumped, vertical external-cavity surface-emitting laser with an intracavity frequency-doubling crystal.
MRI tools for assessment of microstructure and nephron function of the kidney (2016)

MRI can provide excellent detail of renal structure and function. Recently, novel MR contrast mechanisms and imaging tools have been developed to evaluate microscopic kidney structures including the tubules and glomeruli. Quantitative MRI can assess local tubular function and is able to determine the concentrating mechanism of the kidney noninvasively in real time. Measuring single nephron function is now a near possibility. In parallel to advancing imaging techniques for kidney microstructure is a need to carefully understand the relationship between the local source of MRI contrast and the underlying physiological change. The development of these imaging markers can impact the accurate diagnosis and treatment of kidney disease. This study reviews the novel tools to examine kidney microstructure and local function and demonstrates the application of these methods in renal pathophysiology.
Color Imaging <i>via</i> Nearest Neighbor Hole Coupling in Plasmonic Color Filters Integrated onto a Complementary Metal-Oxide Semiconductor Image Sensor (2013)

State-of-the-art CMOS imagers are composed of very small pixels, so it is critical for plasmonic imaging to understand the optical response of finite-size hole arrays and their coupling efficiency to CMOS image sensor pixels. Here, we demonstrate that the transmission spectra of finite-size hole arrays can be accurately described by only accounting for up to the second nearest-neighbor scattering-absorption interactions of hole pairs, thus making hole arrays appealing for close-packed color filters for imaging applications. Using this model, we find that the peak transmission efficiency of a square-shaped hole array with a triangular lattice reaches ∼90% that of an infinite array at an extent of ∼6 × 6 μm(2), the smallest size array showing near-infinite array transmission properties. Finally, we experimentally validate our findings by investigating the transmission and imaging characteristics of a 360 × 320 pixel plasmonic color filter array composed of 5.6 × 5.6 μm(2) RGB color filters integrated onto a commercial black and white 1/2.8 in. CMOS image sensor, demonstrating full-color high resolution plasmonic imaging. Our results show good color fidelity with a 6-color-averaged color difference metric (ΔE) in the range of 16.6-19.3, after white balancing and color-matrix correcting raw images taken with f-numbers ranging from 1.8 to 16. The integrated peak filter transmission efficiencies are measured to be in the 50% range, with a FWHM of 200 nm for all three RGB filters, in good agreement with the spectral response of isolated unmounted color filters.
Built-in self-test of logic blocks in FPGAs (Finally, a free lunch: BIST without overhead!) (2002)

We present a new approach for Field Programmable Gate Array (FPGA) testing that exploits the reprogrammability of FPGAs to create Built-In Self-Test (BIST) logic only during off-line test. As a result, BIST is achieved without any area overhead or performance penalties to the system function implemented by the FPGA. Our approach is applicable to all levels of testing, achieves maximal fault coverage, and all tests are applied at-speed. We describe the BIST architecture used to test all the programmable logic blocks in an FPGA and the configurations required to implement our approach using a commercial FPGA. We also discuss implementation problems caused by CAD tool limitations and limited architectural resources, and we describe techniques which overcome these limitations.
3D microfluidic ex vivo culture of organotypic tumor spheroids to model immune checkpoint blockade (2018)

Microfluidic culture has the potential to revolutionize cancer diagnosis and therapy. Indeed, several microdevices are being developed specifically for clinical use to test novel cancer therapeutics. To be effective, these platforms need to replicate the continuous interactions that exist between tumor cells and non-tumor cell elements of the tumor microenvironment through direct cell–cell or cell–matrix contact or by the secretion of signaling factors such as cytokines, chemokines and growth factors. Given the challenges of personalized or precision cancer therapy, especially with the advent of novel immunotherapies, a critical need exists for more sophisticated ex vivo diagnostic systems that recapitulate patient-specific tumor biology with the potential to predict response to immune-based therapies in real-time. Here, we present details of a method to screen for the response of patient tumors to immune checkpoint blockade therapy, first reported in Jenkins et al. Cancer Discovery, 2018, 8, 196–215, with updated evaluation of murine- and patient-derived organotypic tumor spheroids (MDOTS/PDOTS), including evaluation of the requirement for 3D microfluidic culture in MDOTS, demonstration of immune-checkpoint sensitivity of PDOTS, and expanded evaluation of tumor–immune interactions using RNA-sequencing to infer changes in the tumor–immune microenvironment. We also examine some potential improvements to current systems and discuss the challenges in translating such diagnostic assays to the clinic.
Magnetic head and method of production thereof (1983)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Norimoto Nouchi, Kenji Kanai, Nobuyuki Kaminaka, Noboru Nomura; Magnetic head and method of production thereof. J. Acoust. Soc. Am. 1 May 1983; 73 (5): 1892. https://doi.org/10.1121/1.389294 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAcoustical Society of AmericaThe Journal of the Acoustical Society of America Search Advanced Search |Citation Search
ARB-1740, a RNA Interference Therapeutic for Chronic Hepatitis B Infection (2018)

Current approved nucleoside analogue treatments for chronic hepatitis B virus (HBV) infection are effective at controlling viral titer but are not curative and have minimal impact on the production of viral proteins such as surface antigen (HBsAg), the HBV envelope protein believed to play a role in maintaining the immune tolerant state required for viral persistence. Novel agents are needed to effect HBV cure, and reduction of HBV antigenemia may potentiate activation of effective and long-lasting host immune control. ARB-1740 is a clinical stage RNA interference agent composed of three siRNAs delivered using lipid nanoparticle technology. In a number of cell and animal models of HBV, ARB-1740 caused HBV RNA reduction, leading to inhibition of multiple elements of the viral life cycle including HBsAg, HBeAg, and HBcAg viral proteins as well as replication marker HBV DNA. ARB-1740 demonstrated pan-genotypic activity in vitro and in vivo, targeting three distinct highly conserved regions of the HBV genome, and effectively inhibited replication of nucleoside analogue-resistant HBV variants. Combination of ARB-1740 with a capsid inhibitor and pegylated interferon-alpha led to greater liver HBsAg reduction which correlated with more robust induction of innate immune responses in a human chimeric mouse model of HBV. The preclinical profile of ARB-1740 demonstrates the promise of RNA interference and HBV antigen reduction in treatment strategies driving toward a cure for HBV.
Preparation of Rapeseed Protein Concentrates and Isolates Using Ultrafiltration (1984)

ABSTRACT A novel process based on water leaching and ultrafiltration was developed for the production of rapeseed‐protein products low in glucosinolates. The meal was contacted with water in two leaching stages, and the dissolved proteins were recovered in a two‐stage ultrafiltration process. The first water extract was ultrafiltered and the retentate was diluted with the second extract, and then ultrafiltered again. Four ultratiltration membranes, with molecular weight cut‐offs between 5000 and 100,000 daltons were tested. The process produced a meal, representing 75% of the feed weight, containing 0.2 mg/g of glucosinolates. A protein isolate, which contained 0.42 mg/g glucosinolates and 80.4% protein, represented a further 10% of the feed.
New Hardware and Software Design of a Field-Deployable Real-Time Laser-Based Non-Intrusive Detection System for Measurement of True Travel Time on the Highway (2001)

A new version of a field-deployable real-time laser-based detection system has been developed using new techniques of electronics and optics. The laser-based non-intrusive detection system uses a laser line that is projected onto the ground as a probe. The reflected light is collected and focused into a photodiode array by an optical system. Vehicle presence is detected based on the absence of reflected laser light. By placing two identical laser/sensor pairs at a known distance apart, the speeds of both the front and rear of a vehicle are measured based on the times when each sensor is triggered. The length of each vehicle is determined by using these speed measurements and the residence time of the vehicle under each sensor. A new version field prototype of a detection system for real-time measurement of delineations of moving vehicles for highway testing has been developed based on our previous research on the laboratory prototype of the system. The new version utilizes new techniques in electronics, optics and software. The testing results show that the new system can obtain the accuracy of measurement necessary to distinguish moving vehicles on the highway. It is an important step to approach the final goal of this project, described in the last report as developing a roadway detection system that can be used to gather reliable travel time data non-intrusively. The new system quantitatively proved that the principle of measurement is feasible, instead of qualitatively as did the last version system. Several tests have been done with the field prototype system on the highway. The software for real-time data acquisition, data processing and graphical user interface has been developed in the Windows NT system with RTX real-time extension. In the software, the speed, acceleration, and length of a detected vehicle can be calculated and displayed simultaneously. This document describes the design and implementation of each functional component and software of the new field prototype system. The measurement and calculation of laser power has been performed to ensure that the system is safe to expose to the public during field tests and future operation on the highway.
Aminodifluorosulfinium Tetrafluoroborate Salts as Stable and Crystalline Deoxofluorinating Reagents (2009)

Aminodifluorosulfinium tetrafluoroborate salts were found to act as efficient deoxofluorinating reagents when promoted by an exogenous fluoride source and, in most cases, exhibited greater selectivity by providing less elimination byproduct as compared to DAST and Deoxo-Fluor. Aminodifluorosulfinium tetrafluoroborates are easy handled crystalline salts that show enhanced thermal stability over dialkylaminosulfur trifluorides, are storage-stable, and unlike DAST and Deoxo-Fluor do not react violently with water.
<title>Integration of microfluidics/electrochemical system for trace metal analysis by stripping voltammetry</title> (1999)

Microanalytical systems based on a microfluidics/electrochemical detection scheme were developed. Individual modules, such as microfabricated piezoelectrically actuated pumps and a microelectrochemical cell were integrated onto portable platforms. This allows rapid change-out and repair of individual components by incorporating `plug and play' concepts now standard in PC's. Two different integration schemes were used for construction of the microanalytical systems based on microfluidics/electrochemical detection. In first scheme, all individual modules were integrated in the surface of the standard microfluidic platform based on a plug-and-play design. Microelectrochemical flow cell which integrated three electrodes based on a wall-jet design was fabricated on polymer substrate. The microelectrochemical flow cell was then plugged directly into the microfluidic platform. Another integration scheme was based on a multilayer lamination method utilizing stacking modules with different functionality to achieve a compact microanalytical device. Application of the microanalytical system for detection of lead in river water and saliva samples using stripping voltammetry is described.