gebhart/patrepeval huggingface dataset:
SHCC® - Entwicklung eines neuen Konzeptes für Solar-Hybrid-Kraftwerke (2009)

In the medium term Solar Hybrid Combined Cycle (SHCC ® ) power plants are expected to play an important role in power generation since they are able to supply the electricity market its requirements while utilising existing limited and high grade natural resources economically. SHCC ® powerplants are characterised by the integration of high temperature solar heat into the gas turbine process and in addition - depending on the scheme of the process cycle - downstream into the steam cycle. The input of the solar heat is a done between compressor outlet and combustor inlet of the gas turbine either by direct solar thermal heating inside the receivers of the solar tower or by indirect heating via interconnection of a heat transfer medium. In addition high efficiency of a hybrid power plant process based both on high temperature solar heat and fossil fuel, the concept has considerable advantages in the permanent availability of the power plant output by the combination of both energy sources. Thus, the SHCC ® concept requires no additional standby capacity. The development of the SHCC ® concept is funded by the Federal Ministry for Environment, Nature Conservation and Nuclear Safety of the Federal Republic of Germany.
Cross-Clade HIV-1 Neutralizing Antibodies Induced with V3-Scaffold Protein Immunogens following Priming with gp120 DNA (2011)

The V3 epitope is a known target for HIV-1 neutralizing antibodies (NAbs), and V3-scaffold fusion proteins used as boosting immunogens after gp120 DNA priming were previously shown to induce NAbs in rabbits. Here, we evaluated whether the breadth and potency of the NAb response could be improved when boosted with rationally designed V3-scaffold immunogens. Rabbits were primed with codon-optimized clade C gp120 DNA and boosted with one of five V3-cholera toxin B fusion proteins (V3-CTBs) or with double combinations of these. The inserts in these immunogens were designed to display V3 epitopes shared by the majority of global HIV-1 isolates. Double combinations of V3-CTB immunogens generally induced more broad and potent NAbs than did boosts with single V3-CTB immunogens, with the most potent and broad NAbs elicited with the V3-CTB carrying the consensus V3 of clade C (V3(C)-CTB), or with double combinations of V3-CTB immunogens that included V3(C)-CTB. Neutralization of tier 1 and 2 pseudoviruses from clades AG, B, and C and of peripheral blood mononuclear cell (PBMC)-grown primary viruses from clades A, AG, and B was achieved, demonstrating that priming with gp120 DNA followed by boosts with V3-scaffold immunogens effectively elicits cross-clade NAbs. Focusing on the V3 region is a first step in designing a vaccine targeting protective epitopes, a strategy with potential advantages over the use of Env, a molecule that evolved to protect the virus by poorly inducing NAbs and by shielding the epitopes that are most critical for infectivity.
Physics and Applications of One-Way Magneto-Optical Photonic Crystals (2010)

We demonstrate experimentally one-way waveguiding in a gyromagnetic photonic crystal. The complete suppression of back-scattering, even in the presence of very large scatterers, allows intriguing applications such as slow light.
Reaction of sulfur trioxide with cyclic fluorovinyl ethers (1977)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReaction of sulfur trioxide with cyclic fluorovinyl ethersBruce E. Smart and Carl G. KrespanCite this: J. Am. Chem. Soc. 1977, 99, 4, 1218–1221Publication Date (Print):February 1, 1977Publication History Published online1 May 2002Published inissue 1 February 1977https://pubs.acs.org/doi/10.1021/ja00446a038https://doi.org/10.1021/ja00446a038research-articleACS PublicationsRequest reuse permissionsArticle Views176Altmetric-Citations18LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
High-performance phosphorescent white-stacked organic light-emitting devices for solid-state lighting (2012)

In this work we report exceptional efficacy, lifetime and color stability for all-phosphorescent white stacked organic light-emitting devices (SOLED®s). We report data for all-phosphorescent white SOLED pixels with two emissive units connected in series by a charge generation layer (CGL). At 3,000 cd/m2, efficacy = 54 to 56 lm/W and lifetime to 70% of initial luminance LT70 ≈ 20,000 h, with color rendering index (CRI) = 82 to 83 and chromaticity meeting Energy Star criteria. We further report data for a 15 cm×15 cm white SOLED panel that operates at 3,000 cd/m2 with 48 lm/W efficacy, CRI = 86 and chromaticity meeting Energy Star criteria. The panel has extremely low operating temperature that is only 6.4°C above ambient, and exceptional lifetime of LT70 ≈ 13,000 h when operated at 3,000 cd/m2.
<title>Fiber Laser Gyroscopes</title> (1976)

The application of the optical fiber waveguides to laser gyroscopes is divided into two sections: 1) The ring interferometer and 2) The ring laser. Experiments show that a well defined, stable interference pattern can be obtained using a single mode fiber. This together with the experimentally obtained coupling efficiency of laser radiation into the fiber (-50%) indicate that in addition to a sensitive ring interferometer gyroscope a ring laser gyroscope can be built using a single mode fiber waveguide as the passive part of the laser cavity.© (1976) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
Thiols and Selenols as Electron‐Relay Catalysts for Disulfide‐Bond Reduction (2013)

Pass them on! Dithiobutylamine immobilized on a resin is a useful reagent for the reduction of disulfide bonds. Its ability to reduce a disulfide bond in a protein is enhanced greatly if used along with a soluble strained cyclic disulfide or mixed diselenide that relays electrons from the resin to the protein. This electron-relay catalysis system provides distinct advantages over the use of excess soluble reducing agent alone.
Automated Cardiac-Tissue Identification in Composite Strain-Encoded (C-SENC) Images Using Fuzzy K-Means and Bayesian Classifier (2010)

Composite Strain Encoding (C-SENC) is an MRI acquisition technique for simultaneous acquisition of cardiac tissue viability and contractility images. It combines the use of black-blood delayed-enhancement imaging to identify the infracted (dead) tissue inside the heart wall muscle and the ability to image myocardial deformation (MI) from the strain-encoding (SENC) imaging technique. In this work, we propose an automatic image processing technique to identify the different heart tissues. This provides physicians with a better clinical decision-making tool in patients with myocardial infarction. The technique is based on using Bayesian classifier to identify the background regions in the C-SENC images, and fuzzy clustering technique to identify the different types of the heart tissues. The proposed method is tested using numerical simulations of the heart C-SENC images with MI and real images of patients. The results show that the proposed technique is able to identify the different components of the image with a high accuracy.
A mass-customizable dermal patch with discrete colorimetric indicators for personalized sweat rate quantification (2019)

In this paper, we present a disposable, colorimetric, user-friendly and mass-customizable dermal patch for chronological collection and discrete real-time in situ measurement of sweat secretion over a small area of skin. The patch consists of a laminated filter paper patterned into radially arranged channels/fingers with water-activated dyes at their tips. As channels are filled during perspiration, their tips change color once fully saturated, providing easily identifiable levels of water loss which in turn can be mapped to personal dehydration levels. The patch can be manufactured at low cost in a variety of sizes to allow hydration monitoring for individuals participating in activities under different conditions (intensity, temperature, humidity, etc.). Furthermore, we describe an analytical model that enables mass customization of such a flexible wearable system accommodating a broad range of sweat rates and volumes to generate patch designs that are personalized to an individual's sweat rate, desired time of usage, and the temporal resolution of the required feedback. As a proof-of-concept demonstration, we characterized laser-fabricated patches that cover (7 cm × 5 cm) area of skin having various wicking materials, thicknesses (180-540 µm), and pore sizes (3-11 µm). Tests were conducted at various flow rates simulating different sweating intensities in the range of 1.5-15 mg/cm<sup>2</sup>/min. Experimental results for the case of a half-marathon runner targeting 90 min of usage and sweating at a rate of 1.5 mg/cm<sup>2</sup>/min indicated measurement accuracy of 98.3% when the patch is completely filled.
Dietary arginine prevents atherogenesis in the coronary artery of the hypercholesterolemic rabbit (1994)

Dietary supplements of L-arginine prevent intimal thickening in the coronary arteries of hypercholesterolemic rabbits. This antiatherogenic effect is not due to an alteration in plasma total cholesterol, HDL cholesterol or caloric or nitrogen balance. The data are consistent with the hypothesis that nitric oxide has antiatherogenic properties.
Temperature derivative battery charge control (1985)

A new battery charge termination technique for Ni-Cd batteries will be presented, which is especially effective in low earth orbit application. End of charge termination is based on the temperature increase at end of charge using the temperature derivative detection principle. This makes the end of charge termination practically insensitive to environmental temperature, depth of discharge and solar array charge current fluctuation and guarantees predictable battery voltages, long battery cycle life and minimum thermal dissipation. It also requires about 30% less charging power compared to the conventional voltage-limited charging technique.
Three-dimensional optical tomographic imaging of scattering objects in tissue-simulating turbid media using independent component analysis (2005)

An information-theory-based approach for the detection and three-dimensional localization of scattering targets embedded in a turbid medium, such as a tumor in the breast, is introduced. The approach uses multisource illumination of the medium, multidetector transillumination signal acquisition, and independent component analysis of the information theory for target detection and localization. The efficacy of the approach is demonstrated by detecting and obtaining location information about scattering targets embedded in human breast tissue-simulating turbid media of thickness 50 times the transport mean-free path.
Effect of optical aberrations on intraocular pressure measurements using a microscale optical implant in ex vivo rabbit eyes (2018)

Elevated intraocular pressure (IOP) is the only modifiable major risk factor of glaucoma. Recently, accurate and continuous IOP monitoring has been demonstrated in vivo using an implantable sensor based on optical resonance with remote optical readout to improve patient outcomes. Here, we investigate the relationship between optical aberrations of ex vivo rabbit eyes and the performance of the IOP sensor using a custom-built setup integrated with a Shack-Hartmann sensor. The sensor readouts became less accurate as the aberrations increased in magnitude, but they remained within the clinically acceptable range. For root-mean-square wavefront errors of 0.10 to 0.94 μm, the accuracy and the signal-to-noise ratio were 0.58 ± 0.32 mm Hg and 15.57 ± 4.85 dB, respectively.
THE NOGO SIGNALING PATHWAY FOR REGENERATION BLOCK (2004)

▪ Abstract A hostile environment and decreased regenerative capacity may contribute to the failure of axon regeneration in the adult central nervous system. Recent studies leading to the identification of several myelin-associated inhibitors and their signaling molecules provide opportunitities to assess the contribution of these inhibitory molecules in restricting axon regeneration. These findings may ultimately allow for the development of strategies to alleviate the inhibitory effects of such molecules in an effort to encourage axon regeneration after spinal cord and brain injury.
Macro-scale acoustophoretic separation of lipid particles from red blood cells (2013)

Autologous blood salvage is frequently used in cardiac surgery. However, shed mediastinal blood contains lipid particles ranging in size from 10 to 60 μm. Lipid emboli flow subsequently lodge in the brain capillaries resulting in strokes, leading to neurocognitive dysfunction and death. A novel acoustophoretic filtration system has been developed to separate the lipids from the red blood cells (RBCs). The system works at the macro-scale, supporting flow rates in excess of 2 L/h. The system is designed such that the acoustic radiation force is able to overcome the combined effects of fluid drag and buoyancy forces. Both RBCs and lipid particles are therefore trapped in the ultrasonic standing wave. Due to the opposite contrast factors of lipids and RBCs, the two components separate at opposite nodes within the standing wave, with lipids concentrating at pressure anti-nodes and RBCs at pressure nodes. Subsequent gravitational separation is used to separate the lipids and RBCs. Preliminary results were obtained with a suspension of 10x diluted bovine blood mixed with a 0.75% safflower oil emulsion. Measurements indicate a 15 fold increase in hematocrit of the captured RBCs when compared to the original sample solution, and an excellent separation of the oil droplets.
EZ-Pass: An Energy & Performance-Efficient Power-Gating Router Architecture for Scalable NoCs (2017)

With technology scaling into nanometer regime, static power is becoming the dominant factor in the overall power consumption of Network-on-Chips (NoCs). Static power can be reduced by powering off routers during consecutive idle time through power-gating techniques. However, power-gating techniques suffer from a large wake-up latency to wake up the powered-off routers. Recent research aims to improve the wake-up latency penalty by hiding it through early wake-up techniques. However, these techniques do not exploit the full advantage of power-gating due to the early wake-up. Consequently, they do not achieve significant power savings. In this paper, we propose an architecture called Easy Pass (EZ-Pass) router that remedies the large wake-up latency overheads while providing significant static power savings. The proposed architecture takes advantage of idle resources in the network interface to transmit packets without waking up the router. Additionally, the technique hides the wake-up latency by continuing to provide packet transmission during the wake-up phase. We use full system simulation to evaluate our EZ-Pass router on a 64-core NoC with a mesh topology using PARSEC benchmark suites. Our results show that the proposed router reduces static power by up to 31 percent and overall network latency by up to 32 percent as compared to early-wakeup optimized power-gating techniques.
Development of the IBAD MgO process for HTS coated conductors (2024)

We discuss our progress toward depositing IBAD MgO as a template for subsequent deposition of YBa{sub 2}Cu{sub 3}O{sub 7-{delta}} (YBCO) high temperature superconductors on metallic substrates. We have refined the process by improving substrate preparation and by using reflected high-energy electron diffraction (RHEED) to monitor the growth of IBAD MgO films. Here we present results on our work to optimize the IBAD MgO process for continuous processing of meter lengths. High quality IBAD MgO has been deposited on moving metal tape for use in coated conductor fabrication. By incorporating optimized processing parameters, we have been able to deposit films on moving metallic substrates with in-plane mosaic spreads near 8{sup o}. The subsequent pulsed laser deposition (PLD) of 1.5 {micro}m thick YBCO films has resulted in superconducting transport critical current densities >1MA/cm{sup 2} (75K,SF) on small area samples.
Geometrically Diverse Lariat Peptide Scaffolds Reveal an Untapped Chemical Space of High Membrane Permeability (2020)

Constrained, membrane-permeable peptides offer the possibility of engaging challenging intracellular targets. Structure-permeability relationships have been extensively studied in cyclic peptides whose backbones are cyclized from head to tail, like the membrane permeable and orally bioavailable natural product cyclosporine A. In contrast, the physicochemical properties of lariat peptides, which are cyclized from one of the termini onto a side chain, have received little attention. Many lariat peptide natural products exhibit interesting biological activities, and some, such as griselimycin and didemnin B, are membrane permeable and have intracellular targets. To investigate the structure-permeability relationships in the chemical space exemplified by these natural products, we generated a library of scaffolds using stable isotopes to encode stereochemistry and determined the passive membrane permeability of over 1000 novel lariat peptide scaffolds with molecular weights around 1000. Many lariats were surprisingly permeable, comparable to many known orally bioavailable drugs. Passive permeability was strongly dependent on N-methylation, stereochemistry, and ring topology. A variety of structure-permeability trends were observed including a relationship between alternating stereochemistry and high permeability, as well as a set of highly permeable consensus sequences. For the first time, robust structure-permeability relationships are established in synthetic lariat peptides exceeding 1000 compounds.
Fluorinated and iodinated dopamine agents: D2 imaging agents for PET and SPECT (1993)

A novel series of dual-labeling D2 dopamine agents (labeled with either 18F or 123I for PET or SPECT imaging, respectively) was investigated. Two desired fluorinated and iodinated dopamine agents, FIDA1, (S)-(-)-2-(2-fluoroethoxy)-5-iodo-3-methoxy-N-[(1-ethyl-2- pyrrolidinyl)methyl]-benzamide, and FIDA2, (R)-(+)-2,3-dimethoxy-5-iodo-N-[(1-(4'-fluorobenzyl)-2- pyrrolidinyl)-methyl]benzamide, were synthesized. Both compounds displayed high affinity to the D2 receptor of rat striatal membrane preparations (Kd = 0.13 and 0.02 nM for FIDA1 and FIDA2, respectively). The biodistribution study in rats exhibited high localization in the striata of the brain with the striatum/cerebellum ratio reaching 29.3 and 13.1 at 1 h post iv injection for FIDA1 and FIDA2, respectively. Imaging studies with [18F]- and [123I]FIDA2 in monkeys, with PET and SPECT, respectively, showed comparable high selective striatal uptake. These results suggest that they are potentially useful D2 dopamine receptor imaging agents for PET and SPECT.
NON-DESTRUCTIVE DETECTION OF PITS IN DRIED PLUMS (2005)

An economical, non-destructive device was constructed to detect pits in dried plums (prunes). The devicecompresses the product between a roller and a force transducer, which detects the higher force generated when a pit is present.Two methods of classifying fruit were developed, one based on the maximum magnitude of the compression force and the otheron analysis of the frequency spectra of the force transducer signal during compression. The accuracy of the former was 98.6%for pitted fruit and 69.4% for fruit with pits, versus 99.1% and 75.3% for the latter. The frequency spectra classificationmethod was more accurate, but more complex and costly to implement. The requirement to restrict the compression of the fruitto be non-destructive precludes the possibility to detect small pit fragments using this method. However, the low cost ofmaterials for the device make it a potential method to supplement other technology currently in use to reduce the pit countin the final product.
Organometallic ruthenium (η<sup>6</sup>-<i>p</i>-cymene) complexes interfering with quorum sensing and biofilm formation: an anti-infective approach to combat multidrug-resistance in bacteria (2021)

Organometallic ruthenium complexes of flavonoids as antiquorum sensing agents against pathogens like<italic>Chromobacterium violaceum</italic>ATCC 12472,<italic>Pseudomonas aeruginosa</italic>PAO1 and methicillin-resistant<italic>S. aureus</italic>(MRSA).
Aquaporins Constitute a Large and Highly Divergent Protein Family in Maize (2001)

Aquaporins (AQPs) are an ancient family of channel proteins that transport water and neutral solutes through a pore and are found in all eukaryotes and most prokaryotes. A comparison of the amino acid sequences and phylogenetic analysis of 31 full-length cDNAs of maize (Zea mays) AQPs shows that they comprise four different groups of highly divergent proteins. We have classified them as plasma membrane intinsic proteins (PIPs), tonoplast intrinsic proteins, Nod26-like intrinsic proteins, and small and basic intrinsic proteins. Amino acid sequence identities vary from 16% to 100%, but all sequences share structural motifs and conserved amino acids necessary to stabilize the two loops that form the aqueous pore. Most divergent are the small and basic integral proteins in which the first of the two highly conserved Asn-Pro-Ala motifs of the pore is not conserved, but is represented by alanine-proline-threonine or alanine-proline-serine. We present a model of ZmPIP1-2 based on the three-dimensional structure of mammalian AQP1. Tabulation of the number of times that the AQP sequences are found in a collection of databases that comprises about 470,000 maize cDNAs indicates that a few of the maize AQPs are very highly expressed and many are not abundantly expressed. The phylogenetic analysis supports the interpretation that the divergence of PIPs through gene duplication occurred more recently than the divergence of the members of the other three subfamilies. This study opens the way to analyze the function of the proteins in Xenopus laevis oocytes, determine the tissue specific expression of the genes, recover insertion mutants, and determine the in planta function.