gebhart/patrepeval huggingface dataset:
Sub-micro-gravity capacitive SOI microaccelerometers (2005)

The implementation and preliminary characterization of a new in-plane capacitive microaccelerometer with sub-micro-gravity resolution (<200ng//spl radic/Hz) and very high sensitivity (>15pF/g) is presented. The accelerometers are fabricated in thick (>100 /spl mu/m) silicon-on-insulator (SOI) substrates using a 2-mask fully-dry-release process that provides large seismic mass (>10 mg), reduced capacitive gaps, and reduced in-plane stiffness. The fabricated devices were interfaced to a high resolution switched-capacitor CMOS IC that eliminates the need for area-consuming reference capacitors. The measured sensitivity is 83 mV/mg (17 pF/g) and the output noise floor is -91 dBm/Hz at 10 Hz (corresponding to an acceleration resolution of 170 ng//spl radic/Hz). The IC consumes 6 mW power and measures 0.65 mm/sup 2/ core area.
An effective design method for high power density converters (2008)

Energy Semiconductor Electronics Research Laboratory in AIST has developed an integration design methodology for high power density converters. A part of this work, a novel converter loss estimation method based on Power Converter Platform Concept was proposed. The proposed method estimates the converter loss exactly under real circuit operation condition, by taking the correlation among converter parameters into account. The availability of the proposed method was shown, and the design consideration was carried out for the power conditioner of the photovoltaic solar generation.
Contortrostatin, a snake venom disintegrin, induces αvβ3‐mediated tyrosine phosphorylation of CAS and FAK in tumor cells (2000)

Contortrostatin is a homodimeric disintegrin that inhibits platelet aggregation and cell adhesion to extracellular matrix proteins by blocking integrins. The effect of contortrostatin on integrin-mediated signaling in tumor cells was investigated by studying tyrosine phosphorylation events and activation of specific signaling molecules. We found that at concentrations as low as 1 nM, soluble contortrostatin activates integrin signals leading to increased tyrosine phosphorylation of FAK and CAS, and that these signals are abolished by inhibiting Src family kinases. Using transfected 293 cells expressing specific integrins, it was determined that contortrostatin-generated signals are mediated exclusively by the αvβ3 integrin. This observation was extended by showing that cells lacking αvβ3, but expressing αvβ5 and α5β1, do not respond in this way to contortrostatin treatment. In cells expressing αvβ3, blocking contortrostatin binding with antibodies against αvβ3 completely abrogates contortrostatin signals. Monovalent disintegrins echistatin and flavoridin were incapable of affecting tyrosine phosphorylation alone, but when added simultaneously with contortrostatin, completely inhibited contortrostatin-initiated signals. We propose that the homodimeric nature of contortrostatin imparts the ability to crosslink αvβ3 integrins, causing Src activation and hyperphosphorylation of FAK and CAS. This activity may represent a novel mechanism by which tumor cell motility can be inhibited. J. Cell. Biochem. 79:28–37, 2000. © 2000 Wiley-Liss, Inc.
A novel thermogelling matrix for microchannel DNA sequencing based on poly‐<b><i>N</i></b>‐alkoxyalkylacrylamide copolymers (2003)

We have developed a novel class of thermogelling polymer networks based on poly-N-alkoxyalkylacrylamides, and demonstrated their use as DNA sequencing matrices for high-throughput microchannel electrophoresis in capillary arrays. Polymers and copolymers of N-ethoxyethylacrylamide (NEEA) and N-methoxyethylacrylamide (NMEA) were synthesized by aqueous-phase free-radical polymerization and characterized by tandem gel permeation chromatography-multi-angle laser light scattering. These copolymer matrices exhibit "re-entrant"-type volume phase transitions, forming entangled networks with high shear viscosity at low (< 20 degrees C) and high (> 35 degrees C) temperatures, and undergoing a "coil-to-globular", lower critical solution temperature (LCST)-like phase transition over an intermediate temperature range (20-35 degrees C). Hence, matrix viscosity is relatively low at room temperature (25 degrees C), and increases rapidly above 35 degrees C. The material properties and phase behavior of these thermogelling polymer networks were studied by steady-shear rheometry. These matrices are easily loaded into capillary arrays at room temperature while existing as viscous fluids, but thermogel above 35 degrees C to form transparent hydrogels via a thermo-associative phase transition. The extent of the intermediate viscosity drop and the final viscosity increase depends on the composition of the copolymers. DNA sequencing by capillary array electrophoresis with four-color laser-induced fluorescence (LIF) detection shows that these thermogelling networks provide enhanced resolution of both small and large DNA sequencing fragments and longer sequencing read lengths, in comparison to appropriate control (closely related, nonthermogelling) polymer networks. In particular, a copolymer comprised of 90% w/w NMEA and 10% w/w NEEA, with a molecular mass of approximately 2 MDa, delivers around 600 bases at 98.5% base-calling accuracy in 100 min of electrophoresis.
Safety and Immunogenicity of a Meningococcal (Groups A, C, Y, W-135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine in Healthy Children Aged 2 to 10 Years in Chile (2005)

Immune responses to meningococcal conjugate (Menactra; MCV-4) and plain polysaccharide (Menomune-A/C/Y/W-135; PSV-4) vaccines against serogroups A, C, Y, and W-135 were assessed in 220 of 1037 Chilean children aged 2 to 10 years participating in a comparative safety trial. Both vaccines were generally well tolerated. Geometric mean serum bactericidal antibody (SBA) titers 28 days postvaccination were comparable in both groups for all four serogroups. Seroconversion was evident in > 97% of MCV-4 and > 90% of PSV-4 vaccinees who tested seronegative at baseline. Menactra safely induced broad and robust immune responses against serogroups A, C, Y and W-135 in this population.
Programmable Real-Time Incoherent Matrix Multiplier for Optical Processing (1985)

Optical matrix processing systems based in part upon outer product decomposition are presented that can not only perform matrix-matrix multiplication but also many linear signal processing functions such as the calculation of the cross-ambiguity function.
Quantitation of cholesterol and phospholipid sorption on silicone hydrogel contact lenses (2013)

The introduction of silicone hydrogel (SiHy) contact lenses to the consumer marketplace necessitates study of the susceptibility of these lenses to spontaneous deposition by hydrophobic lipid components of ocular tears. The use of radioisotopes to measure lipid sorption on SiHy contact lenses gives precise and accurate results but requires institutional infrastructure and compels efficient lipid removal from the lens. This study compares three methods of quantitating phospholipid and cholesterol sorption on SiHy lenses using radiolabeled cholesterol and phosphatidylcholine that were sorbed on lenses from an artificial tear fluid. A triple extraction technique using n-propanol gives the most reliable results. Comparison of sorption on SiHy lenses shows that balafilcon A and senofilcon A lenses sorb similar amounts, while lotrafilcon B lenses sorb comparatively less.
Detecting duplicate web documents using clickthrough data (2011)

The web contains many duplicate and near-duplicate documents. Given that user satisfaction is negatively affected by redundant information in search results, a significant amount of research has been devoted to developing duplicate detection algorithms. However, most such algorithms rely solely on document content to detect duplication, ignoring the fact that a primary goal of duplicate detection is to identify documents that contain redundant information with respect to a particular user query. Similarly, although query-dependent result diversification algorithms compute a query-dependent ranking, they tend to do so on the basis of a query-independent content similarity score.
Transient Transfection and Expression in the Obligate Intracellular Parasite <i>Toxoplasma gondii</i> (1993)

Toxoplasma gondii is a protozoan pathogen that produces severe disease in humans and animals. This obligate intracellular parasite provides an excellent model for the study of how such pathogens are able to invade, survive, and replicate intracellularly. DNA encoding chloramphenicol acetyltransferase was introduced into T. gondii and transiently expressed with the use of three vectors based on different Toxoplasma genes. The ability to introduce genes and have them efficiently and faithfully expressed is an essential tool for understanding the structure-function relation of genes and their products.
NEW DEVELOPMENTS IN MOTORCYCLE BRAKE SYSTEMS (1992)

This paper presents the development of motorcycle brake systems, from the outer shoe brakes up to electronic ABS (Antilock braking systems). ABS problems peculiar to motorcycles are investigated, both in the case of braking in a straight line and braking in a bend. The future development of electronically controlled modern motorcycle brakes is also discussed. For the covering abstract see IRRD 869205.
Compositional non-uniformity in a sputter-deposited amorphous Al–Ta alloy (1989)

Abstract Magnetron sputtering has been employed to deposit amorphous A1—30 at.% Ta coatings on oxide-coated aluminium substrates, which allow excellent adhesion and development of coatings of uniform thickness. High-voltage transmission electron microscopy on ultramicrotomed sections of the coatings revealed fine compositional variations through the thickness of the coating, which are related to the specimen and coating arrangement.
Quantum Cascade Lasers and Its Applications for Life Science (2011)

Quantum Cascade Lasers (QCLs) have become the most useful source of tunable mid-infrared lasers for
Synthesis and characterization of radiopaque magnetic core‐shell nanoparticles for X‐ray imaging applications (2007)

Radiopaque magnetic gamma-Fe(2)O(3)/poly(2-methacryloyloxyethyl(2,3,5-triiodobenzoate)) core-shell nanoparticles of narrow size distribution were prepared by emulsion polymerization of the iodinated monomer 2-methacryloyloxyethyl(2,3,5-triiodobenzoate) in the presence of maghemite (gamma-Fe(2)O(3) nanoparticles coated with a dextran shell are commonly used as contrast agents for magnetic resonance imaging (MRI). The present nanoparticles have similar core-shell structure substituting the dextran for the iodo polymer. These core-shell nanoparticles may therefore be useful as imaging contrast agents to detect various pathogenic zones and to observe different disease states in both modes: X-ray and MRI.
Novel High-Performance Liquid-Crystalline Organic Semiconductors for Thin-Film Transistors (2009)

A novel class of liquid-crystalline organic semiconductors based on 2,5′-bis-[2-(4-pentylphenyl)vinyl]-thieno(3,2-b)thiophene and 2,5′-bis-[2-(4-pentylphenyl)vinyl]-(2,2′)bithiophene were synthesized through proper structural design. The materials exhibited high field-effect mobilities up to 0.15 cm2 V−1 s−1 and current on/off ratio of 1 × 106. The high performance is attributed to their abilities to form highly ordered structures through molecular packing, which is revealed by single-crystal and thin film X-ray diffraction (XRD). The structures were analyzed by polarized optical microscope and showed obvious changes in texture corresponding to the phase changes in DSC diagrams, indicating their abilities to form liquid-crystalline structures. High environmental stabilities have been demonstrated with these new compounds, which is consistent with their low HOMO levels and large band gaps. In addition, UV−vis spectra of the thin films formed from these compounds have showed that their absorption peaks mainly appear in the range of ultraviolet spectrum region, indicating they could be used for the application of those circuits requiring transparency such as optoelectronic devices.
Reusable, compression-sealed fluid cells for surface mounting to planar substrates (2009)

We have developed a universal structure and mechanism for the repeatable, rapid-attachment of a fluid cell to a planar substrate. The fluid cell and all fluidic connections are completely contained in a plastic body such that attachment requires neither adhesives nor modification of the substrate. The geometry of the fluid cell is defined by the active area of the planar substrate (e.g. a sensor array). All required components have been quickly prototyped using Computer Numerical Control (CNC) machining. It is also straight-forward to create an array of fluid cells to attach to a single substrate (e.g. a standard microscope slide). All components are easy to assemble and can be cleaned and reused, making this flexible approach applicable for a wide range of lab-on-a-chip applications.
CEET: Cooperative Energy Efficient Tracking System using Smartphones (2019)

The technological advances in smartphones have brought promising potentials to tracking systems. GPS and WLAN are widely used technologies in recent smartphones for positioning and communication, respectively. However, both GPS and WLAN have serious energy consumption problem. For large scale tracking systems, where tracked people are supposed to move in groups, the continuous usage of the individual smartphones GPS and WiFi is not an energy efficient solution. In this work, we propose a cooperative approach that exploits the coexistence of of multiple communication interfaces (WiFi and Bluetooth) in recent smartphones where nearby smartphones are cooperatively grouped to form a cluster. A cluster is a network of one dynamically selected cluster head and regular members that communicate locally via Bluetooth. The cluster head is responsible of positioning and sharing positioning information with the rest of cluster members. It, also, acts as a gateway between its regular members and the server. We present a clustering approach according to the available energy and the energy cost. Our approach doesnt require any modifications in the recent smartphones equipment. We have formulated the clustering construction problem as a mixed integer program using GAMS. The proposed clustering approach has been evaluated via extensive simulation experiments and the obtained results have been compared with the optimal solution which show very close performance.
Uropathogenic <i>Escherichia coli</i> use <scp>d</scp>‐serine deaminase to modulate infection of the murine urinary tract (2003)

Although once thought to be unique to bacteria, d-amino acids are also produced by mammals. For example, d-serine is excreted in human urine at concentrations ranging from 3.0 to 40 micro g ml-1. An epidemiological survey demonstrated that urine isolates of E. coli are more likely to catabolise d-serine via expression of d-serine deaminase, DsdA than enteric disease isolates. The urosepsis strain, CFT073, and an isogenic dsdA mutant have similar growth kinetics in minimal or complex media. However, relative to the wild type, the dsdA mutant has a pleiomorphic cell shape and a prolonged, 4-6 h lag phase when grown in human urine. This suggests that d-serine catabolism provides a growth advantage in the urinary tract. Unexpectedly, in a direct competition model of urinary tract infection, the dsdA mutant was recovered 300-times more frequently than the wild type in the bladders of mice 48 h after infection. A new model of E. coli uropathogenesis is proposed where growth and gene expression are modulated in response to environmental d-serine levels. In support of this, the CFT073 dsdA mutant is hyperflagellated and more motile than the wild type indicating that intracellular levels of d-serine may directly or indirectly influence the expression of regulons associated with E. coli uropathogenesis.
A Small, Lightweight Borehole Receiver for Crosshole and Downhole Seismic Testing (2012)

Abstract Crosshole and downhole seismic testing have traditionally employed the use of a downhole receiver consisting of geophones in a sealed container along with a separate inflatable bladder for seating the geophones against the inside of the boring. This configuration has been used with success, but these receivers can be relatively large and heavy. As an alternative, a smaller, lighter borehole receiver design has been developed. The prototype tool is approximately 19 cm (7.5 in.) long and 6.4 cm (2.5 in.) in diameter, and it weighs less than 0.68 kg (1.5 lb). The new design is a single pressuremeter-like unit in which small accelerometers are glued to the inside of an inflatable membrane. When inflated, the accelerometers are pressed against the borehole wall or casing, and excellent coupling is achieved. Typical results from field testing indicate that the new tool produces reliable results.
Retro-patellar approach in telescopic nailing of the tibia in children with osteogenesis imperfecta (2021)

IV.
An Efficient Resonant Gate-Drive Scheme for High-Frequency Applications (2012)

Silicon carbide (SiC) and gallium nitride (GaN) devices have been found to withstand high voltages without showing degradation and can be switched at high frequencies, making them attractive for high-power drives. Although Sic/GaN devices can be operated at high temperature and high frequencies, it is important to develop gate-drive circuits to efficiently turn on and off these devices at high speeds. This paper proposes a resonant gate-drive circuit that aims at reducing the power loss associated with high-frequency switching of power insulated gate bipolar transistors/metal–oxide–semiconductor field-effect transistors. The main thrust of the circuit is its application to the motor-drive industry. The proposed circuit is compared with traditional gate-drive circuits from the points of view of power consumption and switching speed. Experimental results are given to illustrate the concept. Test results show that the power consumption using the proposed circuit reduces by a factor of greater than 5 compared with a traditional gate-drive circuit.
The omnipolar camera: A new approach to stereo immersive capture (2013)

We introduce in this paper a camera setup for stereo immersive (omnistereo) capture. An omnistereo pair of images gives stereo information up to 360 degrees around a central observer. Previous methods to produce omnistereo images assume a static scene in order to stitch together multiple images captured by a stereo camera rotating on a fixed tripod. Our omnipolar camera setup uses a minimum of 3 cameras with fisheye lenses. The multiple epipoles are used as locations to stitch the images together and produce omnistereo images with no horizontal misalignments due to parallax. We show results of using 3 cameras to capture an unconstrained dynamic scene while the camera is travelling. The produced omnistereo videos are formatted to be displayed on a cylindrical screen or dome.
A Multisampling SVM Scheme for Current Source Converters With Superior Harmonic Performance (2009)

The device switching frequency of current source converters (CSCs) in high-power medium-voltage applications is usually several hundred Hz. Selective harmonic elimination (SHE) has been the dominant modulation scheme because of its capability to eliminate unwanted low-order harmonics at low switching frequencies. Conventional space vector modulation (SVM), as another CSC modulation scheme, provides variable modulation index control but its output contains low-order harmonics with high magnitudes. In this paper, a multisampling SVM (MS-SVM) is proposed to substantially suppress the low-order harmonics in practical CSC-based drives. Investigation of the switching frequency of the proposed modulation method is carried out and methods to reduce additional switchings are developed. The proposed MS-SVM method exhibits a superior low-order harmonic performance comparable to that of SHE and provides the same fast and flexible control capability as the conventional SVM. Simulation and experimental results are provided to verify the proposed methods.
Unilateral Microform Cleft Lip Repair (2015)

Based on the muscle tension line group theory, using this technique offers the ability to adduct the nasal alar effectively to form a good nasal sill and philtrum.
Mouse model of Helicobacter pylori infection: studies of gastric function and ulcer healing (1999)

Conventional mice with gastric ulcers can be successfully infected by both toxigenic and nontoxigenic H. pylori strains, and this infection causes an immediate suppression of gastric secretion and markedly delays the healing of ulcers due to the fall in mucosal microcirculation in the ulcer region, cytokine release and an impairment in the gastrin-somatostatin link that appears to be independent of gastritis and more pronounced with infection of toxigenic than nontoxigenic strains.
Appendix A: Call Progress Time Measurement in IP Telephony (2003)

In Appendix A, we present methodologies to measure the call progress time, and to automate the VoIP call setup for tests and measurements.
Retinoic acid disrupts the Golgi apparatus and increases the cytosolic routing of specific protein toxins. (1994)

All-trans retinoic acid can specifically increase receptor mediated intoxication of ricin A chain immunotoxins more than 10,000 times, whereas fluid phase endocytosis of ricin A chain alone or ricin A chain immunotoxins was not influenced by retinoic acid. The immunotoxin activation by retinoic acid does not require RNA or protein synthesis and is not a consequence of increased receptor binding of the immunotoxin. Vitamin D3 and thyroid hormone T3, that activate retinoic acid receptor (RAR) cognates, forming heterodimers with retinoid X receptor (RXR), do not affect the potency of immunotoxins. Among other retinoids tested, 13-cis retinoic acid, which binds neither RAR nor RXR, also increases the potency of the ricin A chain immunotoxin. Therefore, retinoic acid receptor activation does not appear to be necessary for immunotoxin activity. Retinoic acid potentiation of immunotoxins is prevented by brefeldin A (BFA) indicating that in the presence of retinoic acid, the immunotoxin is efficiently routed through the Golgi apparatus en route to the cytoplasm. Directly examining cells with a monoclonal antibody (Mab) against mannosidase II, a Golgi apparatus marker enzyme, demonstrates that the Golgi apparatus changes upon treatment with retinoic acid from a perinuclear network to a diffuse aggregate. Within 60 min after removal of retinoic acid the cell reassembles the perinuclear Golgi network indistinguishable with that of normal control cells. C6-NBD-ceramide, a vital stain for the Golgi apparatus, shows that retinoic acid prevents the fluorescent staining of the Golgi apparatus and eliminates fluorescence of C6-NBD-ceramide prestained Golgi apparatus. Electron microscopy of retinoic acid-treated cells demonstrates the specific absence of any normal looking Golgi apparatus and a perinuclear vacuolar structure very similar to that seen in monensin-treated cells. This vacuolization disappears after removal of the retinoic acid and a perinuclear Golgi stacking reappears. These results indicate that retinoic acid alters intracellular routing, probably through the Golgi apparatus, potentiating immunotoxin activity indepedently of new gene expression. Retinoic acid appears to be a new reagent to manipulate the Golgi apparatus and intracellular traffic. As retinoic acid and immunotoxins are both in clinical trials for cancer therapy, their combined activity in vivo would be interesting to examine.