gebhart/patrepeval huggingface dataset:
The density based segmentation algorithm for interpreting partial discharge data (2010)

Partial Discharge (PD) signal interpretation has become an essential tool for reliable quality assessment of insulation systems in HV electric machines. Automated classification and recognition of the different types of faults occurring within the insulation system is an important open research problem in this field. In this work, we propose a new approach for the interpretation of PD data. A novel segmentation algorithm is developed to segment PD patterns into their main connected components, with the goal of using these segments later on, to extract distinctive features necessary for fault identification and classification. Several segmentation results are reported along with examples illustrating possible usage in fault identification.
A central spectrum model: A synthesis of auditory-nerve timing and place cues in monaural communication of frequency spectrum (1983)

A probabilistic psychophysical model for monaural communication from the auditory nerve to the brain is given in the form of a tonotopic display of stimulus spectrum, termed central spectrum. The model builds upon prior research demonstrating the potential of neural timing cues from the auditory nerve for conveying information on complex spectra, and was designed to meet the quantified demands of the psychophysics of frequency measurement. The central spectrum magnitude at each frequency is determined by the response of the auditory-nerve fibre with characteristic frequency matching that frequency. An interval histogram from each fiber is passed through a filter matched to the characteristic frequency of the fiber. This output versus characteristic frequency defines the central spectrum. Detailed analysis demonstrates that efficient probabilistic processing of the central spectrum described known psychophysical properties of frequency measurement in discrimination and periodicity pitch experiments. Psychophysical models based upon the central spectrum model followed by optimum probabilistic pattern recognition are potentially relevant for predicting human communication limits in response to arbitrary sounds of speech and music.
Direct, real-space determination of intergrowths in ZSM-5/ZSM-11 catalysts (1982)

The performance of shape-selective catalysts is thought to be a function of the nature of the intergrowths present in the structure, but hitherto no direct methods of identifying isolated or ordered intergrowths have been available; high resolution electron microscopy is shown to be capable of solving such problems, and in particular single strips of ZSM-11 may be directly identified in ZSM-5.
An Automated Size Recognition Technique for Acetabular Implant in Total Hip Replacement (2011)

Preoperative templating in Total Hip Replacement (THR) is a method to estimate the optimal size and position of the implant. Today, observational (manual) size recognition techniques are still used to find a suitable implant for the patient. Therefore, a digital and automated technique should be developed so that the implant size recognition process can be effectively implemented. For this purpose, we have introduced the new technique for acetabular implant size recognition in THR preoperative planning based on the diameter of acetabulum size. This technique enables the surgeon to recognise a digital acetabular implant size automatically. Ten randomly selected X-rays of unidentified patients were used to test the accuracy and utility of an automated implant size recognition technique. Based on the testing result, the new technique yielded very close results to those obtained by the observational method in nine studies (90%).
Deployment automation with BLITZ (2009)

Minimizing the computing infrastructure (such as processors) in a distributed real-time embedded (DRE) system deployment helps reduce system size, weight, power consumption, and cost. To support software components and applications on the computing infrastructure, the hardware must provide enough processors to ensure that all applications can be scheduled without missing real-time deadlines. In addition to ensuring scheduling constraints, sufficient resources (such as memory) must be available to the software. It is hard to identify the best way(s) of deploying software components on hardware processors to minimize computing infrastructure and meet complex DRE constraints. This paper provides the following contributions to the study of the deployment of software components to hardware in DRE systems: (1) we present an algorithmic deployment technique that minimizes the required number of processors, while adhering to real-time scheduling, resource, and co-location constraints, (2) we show how this technique can be augmented with a harmonic period heuristic to further reduce the number of required processors, and (3) we present empirical data from applying three different deployment algorithms for processor minimization to a flight avionics DRE system.
MagCiM: A Flexible and Non-Volatile Computing-in-Memory Processor for Energy-Efficient Logic Computation (2022)

This paper presents a high-performance and energy efficient processor exploiting a <u>Mag</u>netoresistive-based <u>C</u>omputing-<u>i</u>n-<u>M</u>emory array architecture (so-called MagCiM processor), to perform Boolean logic functions on operands stored in a memory array. The proposed processor efficiently addresses the memory wall and the leakage power consumption problems in conventional processors. The MagCiM processor utilizes mCell memory, a class of Magnetoresistive memory employing only Magnetic Tunnel Junction (MTJ) devices, to realize both computation-in-memory and on-chip instruction and data memories. The mCell memory is characterized by almost zero leakage power, high integration density, high level of reliability, and compatibility with the CMOS VLSI fabrication process. The circuit-level simulation results through comparisons with the previous work reveal that the MagCiM processor provides low occupation area, low power, and energy consumption and offers Normally-off instant-on computing capability, which makes it very suitable for embedded system applications. Based on our evaluations, a conventional processor based on the well-known MIPS architecture consumes about 13 times more energy while having 1.5 times more delay than the MagCiM processor.
High-frequency random DNA insertions upon co-delivery of CRISPR-Cas9 ribonucleoprotein and selectable marker plasmid in rice (2019)

An important advantage of delivering CRISPR reagents into cells as a ribonucleoprotein (RNP) complex is the ability to edit genes without reagents being integrated into the genome. Transient presence of RNP molecules in cells can reduce undesirable off-target effects. One method for RNP delivery into plant cells is the use of a biolistic gun. To facilitate selection of transformed cells during RNP delivery, a plasmid carrying a selectable marker gene can be co-delivered with the RNP to enrich for transformed/edited cells. In this work, we compare targeted mutagenesis in rice using three different delivery platforms: biolistic RNP/DNA co-delivery; biolistic DNA delivery; and Agrobacterium-mediated delivery. All three platforms were successful in generating desired mutations at the target sites. However, we observed a high frequency (over 14%) of random plasmid or chromosomal DNA fragment insertion at the target sites in transgenic events generated from both biolistic delivery platforms. In contrast, integration of random DNA fragments was not observed in transgenic events generated from the Agrobacterium-mediated method. These data reveal important insights that must be considered when selecting the method for genome-editing reagent delivery in plants, and emphasize the importance of employing appropriate molecular screening methods to detect unintended alterations following genome engineering.
Formation and x-ray crystal structures of (Ph2PN)2[NS(O)NPPh2NPPh2NH2] and Et2NH2+ [(Ph2PN)2(NSO2)]- from the aerial hydrolysis of (Ph2PN)2(NSNR2) (R = Me, Et) (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFormation and x-ray crystal structures of (Ph2PN)2[NS(O)NPPh2NPPh2NH2] and Et2NH2+ [(Ph2PN)2(NSO2)]- from the aerial hydrolysis of (Ph2PN)2(NSNR2) (R = Me, Et)T. Chivers, M. N. S. Rao, and J. F. RichardsonCite this: Inorg. Chem. 1984, 23, 11, 1531–1535Publication Date (Print):May 1, 1984Publication History Published online1 May 2002Published inissue 1 May 1984https://pubs.acs.org/doi/10.1021/ic00179a013https://doi.org/10.1021/ic00179a013research-articleACS PublicationsRequest reuse permissionsArticle Views35Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Le modèle episcopal dans deux Vies du Xe siècle : S. Innocentius de Tortona et S. Prosper de Reggio Emilia (1991)

Deux vies de saints eveques ont ete redigees en Italie du Nord au Xe siecle, celles d'Innocentius de Tortona et de Prosper de Reggio Emilia. Leurs auteurs ont compose librement deux portraits antithetiques de saints eveques. Innocentius apparait comme un prelat «ottonien», protege par l'empereur, et avant tout soucieux de l'etablissement materiel de son Eglise. Il est saint avant de devenir eveque, et cette fonction l'expose plutot au danger que representent les femmes. En revanche, l'hagiogra- phe de Reggio s'est peu soucie de remplir la tâche qu'on attendait sans doute de lui. Il a eu l'idee d'identifier son eveque avec Prosper d'Aquitaine, ce qui lui conferait un certain prestige; mais il ne le presente pas comme le protecteur tout puissant de la cite, mais comme un spirituel indifferent aux problemes temporels, plein d'humilite, et avant tout soucieux de precher l'Evangile.
Performance of room temperature mercuric iodide (HgI/sub 2/) detectors in the ultra low energy x-ray region (2008)

Performance of room temperature mercuric iodide x-ray spectrometers has been recently improved through new fabrication techniques and further development of low noise associated electronic systems. This progress has extended the range of measurements to the ultra low energy x-ray region at room temperature. This paper reports the study of the effect of contact material on the performance of HgI/sub 2/ detectors in the low energy x-ray region.
Expression of <i>c‐met/</i>HGF Receptor in Human Non‐small Cell Lung Carcinomas <i>in vitro</i> and <i>in vivo</i> and Its Prognostic Significance (1996)

The expression of c-met/HGF receptor was evaluated in non-small cell lung cancers (NSCLC) by western blot analysis of 11 established cell lines and 104 surgically resected tissues. All cancer cell lines (eight adenocarcinomas, two squamous cell carcinomas and a large cell carcinoma) showed strong c-met protein bands of 145 kDa and 170 kDa. Moreover, c-met protein was demonstrated in 34 (72.3%) of 47 surgically resected adenocarcinomas, 20 (38.5%) of 52 squamous cell carcinomas and 3 of 5 others, and the results were mostly confirmed immunohistochemically in formalin-fixed and paraffin-embedded tumors of the same case. Although squamous cell carcinomas showed relatively high c-met protein expression in established cell lines, more adenocarcinomas than squamous cell carcinomas showed c-met protein expression in the original cancers. Furthermore, two cell lines used in this study originated from primary cancers negative for c-met protein expression, suggesting that c-met protein expression might be influenced by cultivation. Furthermore, clinicopathological study revealed that NSCLC with c-met protein expression tended to be in a higher pathological tumor stage and to have a worse outcome than those without such expression. In conclusion, c-met protein is expressed in cell lines and primary tumors of NSCLC, and this phenomenon is probably closely related to the aggressive behavior or progression of NSCLC, especially of adenocarcinomas.
Investigation of a Novel Radial Magnetic-Field-Modulated Brushless Double-Rotor Machine Used for HEVs (2012)

A novel brushless compound-structure permanent-magnet synchronous machine (CS-PMSM) with six different topologies is proposed based on the magnetic field modulation principle. As the key part of the brushless CS-PMSM, the radial magnetic-field-modulated brushless double-rotor machine (MFM-BDRM) is investigated on the speed and torque relations of the first-stator magnetic field, the first-PM rotor and the modulating ring rotor by analytical method. Besides, on the basis of analyses of magnetic field distribution in the inner and outer air gap, the back electromagnetic force and torque performance of the radial MFM-BDRM are further studied by finite-element method (FEM). The results indicate that the low power factor is a major problem of the radial MFM-BDRM. Therefore, the influence of parameters, such as combinations of magnetic block number and PM pole pair number, the span ratio and radial thickness of magnetic blocks, and the length of air gap, on the power factor is analyzed. Additionally, to investigate the distribution law of core loss in the radial MFM-BDRM, amplitudes and frequencies of the magnetic fields in each part of the machine are analyzed. Furthermore, considering the weak mechanical strength of modulating ring rotor employing DW310 laminations, an attempt to use iron instead of DW310 in modulating ring rotor is investigated.
Design and Synthesis of Novel 2-Phenylaminopyrimidine (PAP) Derivatives and Their Antiproliferative Effects in Human Chronic Myeloid Leukemia Cells (2009)

A series of novel 2-phenylaminopyrimidine (PAP) derivatives structurally related to STI-571 were designed and synthesized. The abilities of these compounds to inhibit proliferation were tested in human chronic myeloid leukemia K562 cells. (E)-3-(2-bromophenyl)-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)phenyl]acrylamide(12d) was the most effective cell growth inhibitor and was 3-fold more potent than STI-571.
The Case for In-Network Replay Suppression (2017)

We make a case for packet-replay suppression at the network layer, a concept that has been generally neglected. Our contribution is twofold. First, we demonstrate a new attack, the router-reflection attack, that can be launched using compromised routers. In this attack, a compromised router degrades the connectivity of a remote Internet region just by replaying packets. The attack is feasible even if all packets are attributed to their sources, i.e., source authentication is in place, and our evaluation shows that the threat is pervasive---candidate routers for compromise are in the order of hundreds or thousands. Second, we design an in-network mechanism for replay suppression. We start by showing that designing such a mechanism poses unsolved challenges and simple adaptations of end-to-end solutions are not sufficient. Then, we devise, analyze, and implement a highly efficient protocol that suppresses replayed traffic at the network layer without global time synchronization. Our software-router prototype can saturate a 10 Gbps link using only two CPU cores for packet processing.
The Role of Nuclear Factor-&#954;B in Inflammatory Lung Disease (2010)

Nuclear factor-kappaB (NF-kappaB) is one of the most important transcription factors; it has a key role in inflammatory and immune responses, cell adhesion, developmental signals, and anti-apoptosis process. Inflammatory lung diseases such as asthma and chronic obstructive pulmonary disease (COPD) are major causes of morbidity and mortality worldwide. In this review, we highlight the role of NF-kappaB in inflammatory lung disease, the strategies which block the activation of NF-kappaB, and the therapeutic approaches to treating inflammatory lung disease.
Recent Progress in Additive Manufacturing of Fiber Reinforced Polymer Composite (2018)

Abstract Additive manufacturing (AM) has brought about a revolution in the way we can manufacture complex products with customized features. AM has paved its way in the application areas ranging from aerospace, automotive, consumer to biomedical. AM of composites has attracted special attention due to its promise in improving, modifying, and diversifying the properties of generic materials through introducing reinforcements. This review provides a detailed landscape of fiber‐reinforced composites processed via AM techniques. Different AM processes, various material formulations, and strengths and drawbacks of AM methods are discussed. Emphasis is paid to AM techniques focusing on continuous fibers, as they hold the promise of becoming the next‐generation composite fabrication methodology. The article also tries to identify the potential of AM technology for fiber‐reinforced composites and delves into challenges facing the area.
Unveiling the Differences of Secretome of Human Bone Marrow Mesenchymal Stem Cells, Adipose Tissue-Derived Stem Cells, and Human Umbilical Cord Perivascular Cells: A Proteomic Analysis (2016)

The use of human mesenchymal stem cells (hMSCs) has emerged as a possible therapeutic strategy for CNS-related conditions. Research in the last decade strongly suggests that MSC-mediated benefits are closely related with their secretome. Studies published in recent years have shown that the secretome of hMSCs isolated from different tissue sources may present significant variation. With this in mind, the present work performed a comparative proteomic-based analysis through mass spectrometry on the secretome of hMSCs derived from bone marrow (BMSCs), adipose tissue (ASCs), and human umbilical cord perivascular cells (HUCPVCs). The results revealed that BMSCs, ASCs, and HUCPVCs differed in their secretion of neurotrophic, neurogenic, axon guidance, axon growth, and neurodifferentiative proteins, as well as proteins with neuroprotective actions against oxidative stress, apoptosis, and excitotoxicity, which have been shown to be involved in several CNS disorder/injury processes. Although important changes were observed within the secretome of the cell populations that were analyzed, all cell populations shared the capability of secreting important neuroregulatory molecules. The difference in their secretion pattern may indicate that their secretome is specific to a condition of the CNS. Nevertheless, the confirmation that the secretome of MSCs isolated from different tissue sources is rich in neuroregulatory molecules represents an important asset not only for the development of future neuroregenerative strategies but also for their use as a therapeutic option for human clinical trials.
The application of bioisosteres in drug design for novel drug discovery: focusing on acid protease inhibitors (2012)

The authors discuss the importance of bioisostere's design concept based on specific interaction with the corresponding biomolecule. In addition, some strategies for drug discovery based on the bioisostere concept are introduced. Many bioisosteres, which are recognized by corresponding target biomolecules as exhibiting similar biological properties, have been reported to date; most of the recently developed bioisosteres were designed by cheminformatics approaches. Some molecular design softwares and databases are introduced.
Influence of Addition of Polysiloxane on Sintering of Al<sub>2</sub>O<sub>3</sub> (2014)

The effects of adding polysiloxane (polymethylsilsesquioxane) on the sintering behavior, microstructure and hardness of alumina ceramics have been studied. The sintering kinetics of cold-pressed specimens was studied by dilatometry. Polymer sintering aid was used for alumina based ceramics sintered at 1650o C. The sintered materials were characterized using helium picnometry, x-ray diffraction analysis, scanning electron microscopy, transmission electron microscopy, energy dispersive x-ray spectrometry and Vickers indentation. The addition of polymethylsilsesquioxane yielded alumina/Si 2 Al 4 O 4 N 4 composites. The sintering studies in nitrogen atmosphere (1650 °C/1h) revealed that the highest densities were obtained for specimens with 1wt% PMS. The materials prepared with ceramic polymer precursors had higher hardness than the standard specimen. The preparation of ceramic composites using small amounts of polymer precursors is suited for alumina based ceramics. The processing route being simple, it has the potential to enable the manufacture of complex shaped pieces.
Anti-endothelial cell antibodies: detection and characterization using a cellular enzyme-linked immunosorbent assay. (1987)

Anti-endothelial cell antibodies (AECA) have been detected in autoimmune diseases such as systemic lupus erythematosus (SLE) and scleroderma (PSS) but their role in pathogenesis is unknown. Immunofluorescence, immunohistochemistry, complement-dependent antibody lysis, and radioimmunoassay have been used in the past to detect AECA. We have developed a rapid, sensitive, and quantitative cellular enzyme-linked immunosorbent assay (ELISA) to detect and characterize AECA. Sera were obtained from 28 normal volunteers, 28 patients with SLE, and 14 patients with PSS. We also performed studies in 47 patients with various monoclonal gammopathies. Endothelial cells (EC) were obtained from human umbilical veins by standard methods and subcultured on 96-well tissue culture plates without fixation. EC were then sequentially incubated with sera, peroxidase-conjugated goat anti-human Ig (IgG, IgM, or IgA), and substrate. Optical density readings were converted to arbitrary units by developing a standard curve. Heavy-chain specific antibodies were used to determine the class of AECA binding to EC. IgG was purified by using protein A columns and digested with pepsin to obtain F(ab')2 fragments. The mean units of AECA from normals were 19.3 for IgG and 12.5 for IgM. SLE sera showed significant levels of IgM AECA (37 units, P less than 0.001) but not IgG (29 units, P less than 0.1). PSS sera showed significant levels of both IgM AECA (38 units, P = 0.001) and IgG AECA (42.7 units, P less than 0.005). IgA AECA were not detected in normal, SLE, or PSS sera. Blocking Fc receptors with rabbit IgG did not affect the titer of IgG or IgM AECA.(ABSTRACT TRUNCATED AT 250 WORDS)
Early onset epileptic encephalopathy caused by de novo <i><scp>SCN</scp>8A</i> mutations (2014)

Our data reveal that SCN8A mutations can cause variable phenotypes, most of which can be diagnosed as unclassified EOEEs, and rarely as MMPSI. Together with previous reports, our study further indicates that genetic testing of SCN8A should be considered in children with unclassified severe epilepsy.
Determining the Limits of Automated Program Recognition (1989)

This working paper was submitted as a Ph.D. thesis proposal.