gebhart/patrepeval huggingface dataset:
Multiwatt diode-pumped Yb:YAG thin disk laser continuously tunable between 1018 and 1053 nm (1995)

A new powerful source of broadly (35-nm) tunable laser radiation in the near-infrared (near 1030 nm) wavelength range is presented. Inserting a birefringent filter into a 10-W diode-pumped Yb:YAG thin disk laser resonator gives several watts of narrow-linewidth (0.07-nm) continuously tunable cw output power. By taking advantage of the power scalability of the thin disk concept, even hundreds of watts of tunable power with near-diffraction-limited beam quality and high efficiency are feasible. Generation and amplification of subpicosecond pulses with high average and peak powers are also promising applications of the Yb:YAG thin disk laser.
Effects of surface roughness on microwave heating of soil for detection of buried land mines (2000)

Two common techniques proposed for detection of landmines are ground-penetrating radar (GPR.) and IR imagery. Because of the wide diversity of mines, the clutter which is encountered in minefields, and variation caused by the ground surface, the task of interpreting GPR. signals is daunting. Likewise, variations in thermal properties of soil, solar heating, clutter, and surface irregularities lead to limited performance for IR imaging systems.
Palette: Image-to-Image Diffusion Models (2022)

This paper develops a unified framework for image-to-image translation based on conditional diffusion models and evaluates this framework on four challenging image-to-image translation tasks, namely colorization, inpainting, uncropping, and JPEG restoration. Our simple implementation of image-to-image diffusion models outperforms strong GAN and regression baselines on all tasks, without task-specific hyper-parameter tuning, architecture customization, or any auxiliary loss or sophisticated new techniques needed. We uncover the impact of an L2 vs. L1 loss in the denoising diffusion objective on sample diversity, and demonstrate the importance of self-attention in the neural architecture through empirical studies. Importantly, we advocate a unified evaluation protocol based on ImageNet, with human evaluation and sample quality scores (FID, Inception Score, Classification Accuracy of a pre-trained ResNet-50, and Perceptual Distance against original images). We expect this standardized evaluation protocol to play a role in advancing image-to-image translation research. Finally, we show that a generalist, multi-task diffusion model performs as well or better than task-specific specialist counterparts. Check out https://diffusion-palette.github.io/ for an overview of the results and code.
Superior Vena Caval Placement of a Temporary Filter (2001)

Placement of permanent filters in the superior vena cava (SVC) for preventing pulmonary embolism (PE) arising from thrombi superior to the right atrium has rarely been performed. The authors report the first case of temporary filter insertion in the SVC because of upper extremity thrombosis accompanied with PE. After thrombectomy, the temporary filter was successfully removed. It is recommended to use a temporary filter, especially in young patients with upper extremity thrombosis requiring temporary prophylaxis against PE.
HNO/cGMP-dependent antihypertrophic actions of isopropylamine-NONOate in neonatal rat cardiomyocytes: potential therapeutic advantages of HNO over NO˙ (2013)

Nitroxyl (HNO) is a redox congener of NO. We now directly compare the antihypertrophic efficacy of HNO and NO donors in neonatal rat cardiomyocytes and compare their contributing mechanisms of actions in this setting. Isopropylamine-NONOate (IPA-NO) elicited concentration-dependent inhibition of endothelin-1 (ET1)-induced increases in cardiomyocyte size, with similar suppression of hypertrophic genes. Antihypertrophic IPA-NO actions were significantly attenuated by l-cysteine (HNO scavenger), Rp-8-pCTP-cGMPS (cGMP-dependent protein kinase inhibitor), and 1-H-(1,2,4)-oxodiazolo-quinxaline-1-one [ODQ; to target soluble guanylyl cyclase (sGC)] but were unaffected by carboxy-PTIO (NO scavenger) or CGRP8-37 (calcitonin gene-related peptide antagonist). Furthermore, IPA-NO significantly increased cardiomyocyte cGMP 3.5-fold (an l-cysteine-sensitive effect) and stimulated sGC activity threefold, without detectable NO release. IPA-NO also suppressed ET1-induced cardiomyocyte superoxide generation. The pure NO donor diethylamine-NONOate (DEA-NO) reproduced these IPA-NO actions but was sensitive to carboxy-PTIO rather than l-cysteine. Although IPA-NO stimulation of purified sGC was preserved under pyrogallol oxidant stress (in direct contrast to DEA-NO), cardiomyocyte sGC activity after either donor was attenuated by this stress. Excitingly IPA-NO also exhibited acute antihypertrophic actions in response to pressure overload in the intact heart. Together these data strongly suggest that IPA-NO protection against cardiomyocyte hypertrophy is independent of both NO and CGRP but rather utilizes novel HNO activation of cGMP signaling. Thus HNO acutely limits hypertrophy independently of NO, even under conditions of elevated superoxide. Development of longer-acting HNO donors may thus represent an attractive new strategy for the treatment of cardiac hypertrophy, as stand-alone and/or add-on therapy to standard care.
Identification and quantification of fetal red blood cells in maternal blood by a dual‐color flow cytometric method: evaluation of the Fetal Cell Count kit (2007)

With this new dual-color flow cytometric method, accurate evaluation of fetomaternal hemorrhage was achieved even in the face of HbF of maternal origin.
Performance of Psychomotor Skills: A Comparison of Two Teaching Strategies (1991)

This study compares two teaching strategies: textbook assignment and videotape with no faculty assistance, and textbook assignment and videotape with faculty assistance (demonstration of skills and supervised practice) to determine their effect on outcome performance (measurement of blood pressure) and on the student's perceived level of confidence. The intent of the study was to ascertain if the use of mediated instruction without faculty input would decrease faculty-student contact time without adversely affecting performance outcomes. Results of the study revealed that faculty contact is an important factor when students are learning to perform a basic psychomotor skill. It was concluded that mediated instruction is not appropriate as a complete substitute for faculty contact.
Unsupervised Online Anomaly Detection on Multivariate Sensing Time Series Data for Smart Manufacturing (2019)

The emergence of IoT and AI has brought revolutionary change in various application domains. One of them is Industry 4.0, also called Smart Manufacturing, which aims to achieve highly flexible and automated production processes. In this paper, we study a use case of anomaly detection in smart manufacturing using the real data collected from the sensing devices of a factory production line. Our goal is to improve the anomaly detection accuracy at an earlier stage of production line, so that cost and time wasted by possible production failures can be reduced. To overcome the limited and irregular anomaly patterns found from our multivariate sensor dataset, we proposed an unsupervised real-time anomaly detection algorithm based on LSTM-based Auto-Encoder. Our evaluations show that our approach achieved almost 90% accuracy for both precision and recall while other classification or regression based methods only reached 70%~85%.
The energy and width of paired Neel walls in double layer M-R films (1990)

The energy and wall width of paired Neel walls are analytically examined. The walls studied are those which are perpendicular to the easy axes in double-layer MR (magnetoresistive) elements. Specifically, the material examined consisted of two 150-AA-thick magnetic layers separated by 50 AA. The anisotropy constant was assumed to be 20 Oe, the exchange constant 1.25*10/sup -6/ erg/cm, and the saturation magnetization 983 G/4 pi . Wall energies ranged from 0.03 erg/cm/sup 2/ to 1.8 erg/cm/sup 2/ as the total angle of rotation across the wall varied from 60 degrees to 270 degrees . Wall width ranged from 2.0 mu m to 0.5 mu m. The wall energies were found to be approximately one eighth of those of single-layer Neel walls. The wall widths were found to vary less with total wall angle than those encountered with a single-layer Neel wall. The paired Neel walls are generally wider than those for a single-layer film.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Perspectives on Fast-Neutron Mutagenesis of Human Lymphoblastoid Cells (1991)

The effects of low-fluence exposures to (Pu, Be) neutrons (En = 4.2 MeV) have been studied in a sensitive human B-lymphoblastoid cell line, TK6. Mutations were scored for two genetic loci, hypoxanthine phosphoribosyltransferase (hgprt) and thymidine kinase (tk), as a function of dose and dose rate. For exposures limited to less than one cell cycle, the mutation frequency for the hgprt locus was 1.92 X 10(-7)/cGy. When exposures were protracted over multiple cell generations, mutation yields were increased to 6.07 X 10(-7)/cGy. Similar yields were obtained for the induction of tk-deficient mutants with a normal cell generation time (tk-ng) when exposures were carried out at very low dose rates over multiple cell generations. In the series of data presented here, the results obtained for short-duration neutron exposures are compared with data obtained for monoenergetic heavy charged particles of defined linear energy transfer (LET) produced at the BEVALAC accelerator at Lawrence Berkeley Laboratory. TK6 cells have been exposed to beams ranging in atomic number from 20Ne to 40Ar over an energy range from 330 to 670 MeV/amu. Mutation induction was evaluated for both loci for a subset of these beams. The results obtained with 20Ne ions of 425 MeV/amu (LET = 32 keV/microns) and 28Si ions of 670 MeV/amu (LET = 50 keV/microns) closely resemble the mutation yields obtained for brief exposures to (Pu, Be) neutrons. The nature of alterations in DNA structure induced within the tk locus of tk-ng mutants is reviewed for a series of neutron-induced mutants and a series of mutants induced by exposure to 40Ar ions (470 MeV/amu, LET = 95 keV/microns). The mutational spectra for these two types of mutants were similar and were dominated by allele loss mutations. Multilocus deletions inclusive of the c-erbA1 locus were common among tk-deficient mutants induced by these densely ionizing radiations. For the mutants induced by 40Ar ions, it is likely that the mutations were produced by the traversal of the chromosome by a single particle.
An ultra-fast distance sensor based on dynamic speckles generated by acousto-optic deflection (2006)

In this paper, we analyse the applicability of dynamic speckles for distance measurement to any rough surface. The technique is based on spatial filtering of a speckle pattern generated when the object surface is scanned by a laser beam deflected from an acousto-optic device. An extremely short response time was achieved because of the high scanning speed provided by the acousto-optic deflector. We have developed a prototype of the distance-measuring system and studied its performance. The measurement setup has a very simple configuration. The distance can be measured within as short a time as 50 ns, but with rather high inaccuracy caused by the stochastic nature of the speckle effect. The data averaging is easily implemented within a single scan and allows us to achieve an accuracy of 110 µm within the time window of 2.5 µs. An analysis of the factors affecting the performance of the proposed technique is carried out. It is shown that the response time can be diminished by an order of value using an acousto-optic crystal with higher acoustic speed. The proposed technique may be useful for monitoring the geometrical parameters of fast moving or rotating surfaces in various industrial applications.
Tagline: Information Extraction for Semi-Structured Text Elements in Medical Progress Notes. (2012)

Text analysis has become an important research activity in the Department of Veterans Affairs (VA). Statistical text mining and natural language processing have been shown to be very effective for extracting useful information from medical documents. However, neither of these techniques is effective at extracting the information stored in semi-structure text elements. A prototype system (TagLine) was developed as a method for extracting information from the semi-structured portions of text using machine learning. Features for the learning machine were suggested by prior work, as well as by examining the text, and selecting those attributes that help distinguish the various classes of text lines. The classes were derived empirically from the text and guided by an ontology developed by the Consortium for Health Informatics Research (CHIR), a nationwide research initiative focused on medical informatics. Decision trees and Levenshtein approximate string matching techniques were tested and compared on 5,055 unseen lines of text. The performance of the decision tree method was found to be superior to the fuzzy string match method on this task. Decision trees achieved an overall accuracy of 98.5 percent, while the string match method only achieved an accuracy of 87 percent. Overall, the results for line classification were very encouraging. The labels applied to the lines were used to evaluate TagLines' performance for identifying the semi-structures text elements, including tables, slots and fillers. Results for slots and fillers were impressive while the results for tables were also acceptable.
Evaluation of modulation techniques for 5-level inverter based on multicarrier level shift PWM (2014)

Multilevel inverter has become attractive in the power industries and it can be applied in many applications especially in renewable energy systems and improvement of the power quality. On the other hand, the technique used to generate the required switching pulses plays an important role to improve the inverter characteristics. The paper presents an assessment of three different types of control techniques based on multicarrier level shifted PWM (S-IPD, S-POD and S-APOD) applied to a single phase full bridge five level diode clamped inverter. The main parameters considered are the Total Harmonic Distortion (THD) and harmonic spectrum. The reported results are based on the experimental and simulation realization. In addition, the simulation and experimental output voltages and currents waveforms of all mentioned techniques are presented.
Transforming plant biology and breeding with <scp>CRISPR</scp>/Cas9, Cas12 and Cas13 (2018)

Currently, biology is revolutionized by ever growing applications of the CRISPR/Cas system. As discussed in this Review, new avenues have opened up for plant research and breeding by the use of the sequence-specific DNases Cas9 and Cas12 (formerly named Cpf1) and, more recently, the RNase Cas13 (formerly named C2c2). Although double strand break-induced gene editing based on error-prone nonhomologous end joining has been applied to obtain new traits, such as powdery mildew resistance in wheat or improved pathogen resistance and increased yield in tomato, improved technologies based on CRISPR/Cas for programmed change in plant genomes via homologous recombination have recently been developed. Cas9- and Cas12- mediated DNA binding is used to develop tools for many useful applications, such as transcriptional regulation or fluorescence-based imaging of specific chromosomal loci in plant genomes. Cas13 has recently been applied to degrade mRNAs and combat viral RNA replication. By the possibility to address multiple sequences with different guide RNAs and by the simultaneous use of different Cas proteins in a single cell, we should soon be able to achieve complex changes of plant metabolism in a controlled way.
A STATISTICAL ANALYSIS OF GDP AND FINAL CONSUMPTION USING SIMPLE LINEAR REGRESSION. THE CASE OF ROMANIA 1990–2010 (2011)

This paper aims to examine the causal relationship between GDP and final consumption. The authors used linear regression model in which GDP is considered variable results, and final consumption variable factor. In drafting article we used Excel software application that is a modern computing and statistical data analysis.
Learning and Using the Arrow of Time (2018)

We seek to understand the arrow of time in videos - what makes videos look like they are playing forwards or backwards? Can we visualize the cues? Can the arrow of time be a supervisory signal useful for activity analysis? To this end, we build three large-scale video datasets and apply a learning-based approach to these tasks. To learn the arrow of time efficiently and reliably, we design a ConvNet suitable for extended temporal footprints and for class activation visualization, and study the effect of artificial cues, such as cinematographic conventions, on learning. Our trained model achieves state-of-the-art performance on large-scale real-world video datasets. Through cluster analysis and localization of important regions for the prediction, we examine learned visual cues that are consistent among many samples and show when and where they occur. Lastly, we use the trained ConvNet for two applications: self-supervision for action recognition, and video forensics - determining whether Hollywood film clips have been deliberately reversed in time, often used as special effects.
Multivalued Integrated Injection Logic (1977)

A family of circuits for multivalued, in particular quaternary, integrated injection logic is described. The basic elements are the I2L current mirror and I2L threshold gates.
Solution Structure of the Acetylated and Noncleavable Mitochondrial Targeting Signal of Rat Chaperonin 10 (1995)

Chaperonin 10 (Cpn10) is one of only a few mitochondrial matrix proteins synthesized without a cleavable targeting signal. Using a truncated form of Cpn10 and synthetic peptides in mitochondrial import assays, we show that the N-terminal region is both necessary and sufficient for organellar targeting in vitro. To elucidate the structural features of this topogenic signal, peptides representing residues 1-25 of rat Cpn10 were synthesized with and without the naturally occurring N-terminal acetylation. 1H NMR spectroscopy in 20% CF3CH2OH,H2O showed that both peptides assume a stable helix-turn-helix motif and are highly amphiphilic in nature. Chemical shift and coupling constant data revealed that the N-terminal helix is stabilized by N-acetylation, whereas NOE and exchange studies were used to derive a three dimensional structure for the acetylated peptide. These findings are discussed with respect to a recent model predicting that targeting sequences forming a continuous alpha-helix of more than 11 residues cannot adopt a conformation necessary for proteolysis by the matrix located signal peptidases (Hammen, P. K., Gorenstein, D. G., and Weiner, H. (1994) Biochemistry 33, 8610-8617).
Population-level effect of potential HSV2 prophylactic vaccines on HIV incidence in sub-Saharan Africa (2008)

Herpes simplex virus type-2 (HSV2) infection increases HIV transmission. We explore the impact of a potential prophylactic HSV2 vaccination on HIV incidence in Africa using STDSIM an individual-based model. A campaign that achieved 70% coverage over 5 years with a vaccine that reduced susceptibility to HSV2 acquisition and HSV2 reactivation by 75% for 10 years, reduced HIV incidence by 30-40% after 20 years (range 4-66%). Over 20 years, in most scenarios fewer than 100 vaccinations were required to avert one HIV infection. HSV2 vaccines could have a substantial impact on HIV incidence. Intensified efforts are needed to develop an effective HSV2 vaccine.
BIAS-DEPENDENT STRUCTURE IN EXCESS NOISE IN GaAs SCHOTTKY TUNNEL JUNCTIONS (1971)

Large-amplitude excess noise has been observed in the tunneling current of degenerate p-type GaAs–Au Schottky junctions. At 4.2 K the noise voltage exhibits well-defined peaks as a function of bias voltage. The background noise exhibits a 1/f-type spectral response, but the spectral response of some of the peaks indicates that tunneling via surface states with a single average lifetime occurs. Peaks in the noise voltage correspond in bias voltage position with structure in d2I/dV2.
Cobalt Protoporphyrin Pretreatment Protects Human Embryonic Stem Cell-Derived Cardiomyocytes From Hypoxia/Reoxygenation Injury In Vitro and Increases Graft Size and Vascularization In Vivo (2014)

Human embryonic stem cell-derived cardiomyocytes (hESC-CMs) can regenerate infarcted myocardium. However, when implanted into acutely infarcted hearts, few cells survive the first week postimplant. To improve early graft survival, hESC-CMs were pretreated with cobalt protoporphyrin (CoPP), a transcriptional activator of cytoprotective heme oxygenase-1 (HO-1). When hESC-CMs were challenged with an in vitro hypoxia/reoxygenation injury, mimicking cell transplantation into an ischemic site, survival was significantly greater among cells pretreated with CoPP versus phosphate-buffered saline (PBS)-pretreated controls. Compared with PBS-pretreated cells, CoPP-pretreated hESC-CM preparations exhibited higher levels of HO-1 expression, Akt phosphorylation, and vascular endothelial growth factor production, with reduced apoptosis, and a 30% decrease in intracellular reactive oxygen species. For in vivo translation, 1 × 10(7) hESC-CMs were pretreated ex vivo with CoPP or PBS and then injected intramyocardially into rat hearts immediately following acute infarction (permanent coronary ligation). At 1 week, hESC-CM content, assessed by quantitative polymerase chain reaction for human Alu sequences, was 17-fold higher in hearts receiving CoPP- than PBS-pretreated cells. On histomorphometry, cardiomyocyte graft size was 2.6-fold larger in hearts receiving CoPP- than PBS-pretreated cells, occupying up to 12% of the ventricular area. Vascular density of host-perfused human-derived capillaries was significantly greater in grafts composed of CoPP- than PBS-pretreated cells. Taken together, these experiments demonstrate that ex vivo pretreatment of hESC-CMs with a single dose of CoPP before intramyocardial implantation more than doubled resulting graft size and improved early graft vascularization in acutely infarcted hearts. These findings open the door for delivery of these, or other, stem cells during acute interventional therapy following myocardial infarction or ischemia.
Robust facial expression tracking based on composite constraints AAM (2011)

Facial expression tracking is a challenging task because the head pose may change in a large range and the expression is highly non-rigid. It can be formulized as an energy minimization problem. The two most important issues are the construction of the cost function and the selection of the initial value. In this paper, we present a fast and robust expression tracking algorithm called Composite Constraints AAM. Firstly, a novel cost function is proposed to enhance the convergence by combining multiple constraints in a unified framework. Secondly, widely used local features are strictly tested with face videos, and an efficient motion estimation method is presented to provide a good initial value to the iterative optimization process. Experimental result demonstrates that our system can track the head pose and facial expression with very high stability in real time speed.