gebhart/patrepeval huggingface dataset:
Induction of Islet Cytodifferentiation by Fetal Mesenchyme in Adult Pancreatic Ductal Epithelium (1991)

Recombinant tissue consisting of adult ductal epithelium isolated from pancreas and fetal mesenchyme was transplanted subcutaneously in the inguinal region of nude mice or epididymal fat pads of rats with a tissue chamber device for short-term (8-day) or long-term (6- to 12-wk) duration. We found that recombinant tissue underwent morphogenesis and cytodifferentiation, thereby forming islets that contained cells immunocytochemically positive for insulin and glucagon. Islet cytodifferentiation occurred in approximately 20% of the recombinants. In recombinants that developed into islets, the tissue was always in close association with an extracellular matrix, nerves, and blood vessels. Controls consisting of mesenchyme alone or duct epithelium alone showed no evidence of morphogenesis of cytodifferentiation. Pancreatic rudiments were also implanted to serve as positive controls. This is the first demonstration of islet cytodifferentiation from adult duct epithelium.
EnsembleMatrix (2009)

Machine learning is an increasingly used computational tool within human-computer interaction research. While most researchers currently utilize an iterative approach to refining classifier models and performance, we propose that ensemble classification techniques may be a viable and even preferable alternative. In ensemble learning, algorithms combine multiple classifiers to build one that is superior to its components. In this paper, we present EnsembleMatrix, an interactive visualization system that presents a graphical view of confusion matrices to help users understand relative merits of various classifiers. EnsembleMatrix allows users to directly interact with the visualizations in order to explore and build combination models. We evaluate the efficacy of the system and the approach in a user study. Results show that users are able to quickly combine multiple classifiers operating on multiple feature sets to produce an ensemble classifier with accuracy that approaches best-reported performance classifying images in the CalTech-101 dataset.
Blood Coagulation Sensing at the Point of Care (2015)

We describe a new optical coagulation sensing approach termed Optical Thromboelastography (OTEG) that measures a patient’s coagulation status using a drop of blood. In OTEG, laser speckle intensity fluctuations are analyzed during clotting to measure the viscoelastic properties of blood during coagulation and recover information about multiple coagulation metrics within minutes. This technology addresses the critical unmet need to identify and manage patients with an elevated risk of life-threatening hemorrhage, the major cause of in-hospital preventable death. In addition, this innovation may enable rapid coagulation testing for patients who routinely receive oral anticoagulants to prevent venous and arterial thrombosis, the world’s number one killer.
Automatic, Continuous River Stage Measurement with a Millimeter-Wave FM- CW Radar (1993)

River stage measurements at many locations are fundamental for the analysis of dynamic events on rivers, including ice breakup.But, these data are frequently unavailable.A high-resolution, broadband millimeter-wave (26.5 to 40 GHz) Frequency Modulated-Continuous Wave (FM-CW) radar, with real-time data acquisition and digital signal processing capability, was mounted from fixed locations on bridges over the Connecticut River to continuously acquire, process, store and display river stage data during controlled releases of water from a hydropower dam.The radar system provided continuous stage data of accuracy comparable to those acquired by a survey team and a permanent U.S. Geological Survey stream gauging station.The system can be rapidly installed and is capable of acquiring data, including event timing, at 1-, 10-or 60second intervals, around-the-clock, without operator interaction or visual readings.The system sensor can be remotely mounted and monitored, thereby minimizing safety hazards to personnel using direct measurement techniques.Cover: Radar deployed from the covered bridge between Comish, New Hamp - shire, and Windsor, Vermont.
Small FPGA implementations for solving systems of linear equations in finite fields (2015)

Solving systems of linear equations in finite fields is among the most fundamental operations and used extensively in areas of cryptography, signal processing and clustered file system. In order to implement such systems, it is desirable to improve solving systems of linear equations. We propose FPGA implementations for Gaussian elimination in finite fields. Experimental results and comparisons show that our designs provide significant reductions in both area and clock-area product.
New Gas‐Sensing Method for Detecting Carbon Monoxide by Use of the Complex Impedance of a CuO/ZnO Heterocontact under a dc Bias Voltage (1994)

The impedance characteristics of a CuO/ZnO oxide semiconductor heterocontact were investigated to study a new method of gas identification. This was done by applying a dc bias voltage in atmospheres of air‐balanced, flammable CO or H 2 gas (4000 ppm). The frequency dependence of the reactance component showed a characteristic behavior that varied according to the testing atmosphere under the applied negative dc voltage at 400°C. The discrimination of CO gas from H 2 gas in air was demonstrated as feasible by either varying the bias voltage in negative values at constant frequency or sweeping the frequency on a negative bias voltage. The new method of gas identification suggested by the present study uses a ceramic‐semiconductor heterocontact, on which a combination of dc bias voltage and ac signal is applied.
Tuning Carbon Materials for Supercapacitors by Direct Pyrolysis of Seaweeds (2009)

Abstract The sea provides a large variety of seaweeds that, because of their chemical composition, are fantastic precursors of nanotextured carbons. The carbons are obtained by the simple pyrolysis of the seaweeds under a nitrogen atmosphere between 600 and 900 °C, followed by rinsing the product in slightly acidic water. Depending on the origin of the seaweed and on the pyrolysis conditions, the synthesis may be oriented to give an oxygen‐enriched carbon or to give a tuned micro/mesoporous carbon. The samples with a rich oxygenated surface functionality are excellent as supercapacitor electrodes in an aqueous medium whereas the perfectly tuned porous carbons are directly applicable for organic media. In both cases, the specific surface area of the attained carbons does not exceed 1300 m 2 g −1 , which results in high‐density materials. As a consequence, the volumetric capacitance is very high, making these materials more interesting than activated carbons from the point of view of developing small and compact electric power sources. Such versatile carbons, obtained by a simple, ecological, and cheap process, could be well used for environment remediation such as water and air treatment.
Laboratory Selection of a Benzimidazole-Resistant Isolate of Trichostrongylus colubriformis for Ivermectin Resistance (1990)

In vivo ivermectin resistance was selected in an isolate of Trichostrongylus colubriformis (TcR) already known to be benzimidazole resistant. This was accomplished in sheep by using levels of ivermectin calculated to reduce the fecal egg output from each generation of T. colubriformis by congruent to 95%. The first indication of ivermectin resistance was observed with the F10. A dosage-titration trial comparing the parent TcR with the ivermectin-selected F21 demonstrated that the latter was congruent to 20 times more resistant to oral ivermectin therapy in experimentally infected sheep than was the parent isolate. Treatment of the F16 generation with 50 mg/kg of thiabendazole resulted in only 54% egg reduction and confirmed that benzimidazole resistance was stable.
Vivid-colored silicon solar panels with high efficiency and non-iridescent appearance (2019)

A novel approach was proposed for fabricating bright-colored solar cells with high power conversion efficiency and excellent angular insensitivity.
Secure network communication using biometrics (2001)

In this paper we propose an architecture for secure access of computers inside an organization from a remote location. We use biometrics features and a one-time password mechanism on top of secure socket layer (SSL) for authentication. We also provide three layers of security levels for network communication, and also a mechanism for secure file accesses based on the security privileges assigned to various users is proposed. The files to be accessed from the server are categorized depending on their access privileges and encrypted using a key assigned to each category.
Highly Cross-Linked, Self-Doped Polyaniline Exhibiting Unprecedented Hardness (2005)

This report describes a new strategy for the formation of a cross-linked conducting polymer exhibiting enhanced mechanical properties. The approach is demonstrated with poly(anilineboronic acid) which self-cross-links to produce an extremely hard polymer that maintains its electrical conductivity. This strategy offers a completely new approach that may be used to enhance the physical properties of conducting polymers without other modifications.
Benzoxazinones as PPARγ Agonists. 2. SAR of the Amide Substituent and In Vivo Results in a Type 2 Diabetes Model (2003)

A series of benzoxazinones has been synthesized and tested for PPARgamma agonist activity. Synthetic approaches were developed to provide either racemic or chiral compounds. In vitro functional potency could be measured through induction of the aP2 gene, a target of PPARgamma. These studies revealed that compounds with large aliphatic chains at the nitrogen of the benzoxazinone were the most potent. Substitution of the chain was tolerated and in many cases enhanced the in vitro potency of the compound. Select compounds were further tested for metabolic stability, oral bioavailability in rats, and efficacy in db/db mice after 11 days of dosing. In vivo analysis with 13 and 57 demonstrated that the series has potential for the treatment of type 2 diabetes.
Bayesian Graph Convolutional Neural Networks for Semi-Supervised Classification (2019)

Recently, techniques for applying convolutional neural networks to graph-structured data have emerged. Graph convolutional neural networks (GCNNs) have been used to address node and graph classification and matrix completion. Although the performance has been impressive, the current implementations have limited capability to incorporate uncertainty in the graph structure. Almost all GCNNs process a graph as though it is a ground-truth depiction of the relationship between nodes, but often the graphs employed in applications are themselves derived from noisy data or modelling assumptions. Spurious edges may be included; other edges may be missing between nodes that have very strong relationships. In this paper we adopt a Bayesian approach, viewing the observed graph as a realization from a parametric family of random graphs. We then target inference of the joint posterior of the random graph parameters and the node (or graph) labels. We present the Bayesian GCNN framework and develop an iterative learning procedure for the case of assortative mixed-membership stochastic block models. We present the results of experiments that demonstrate that the Bayesian formulation can provide better performance when there are very few labels available during the training process.
Production of ferulic acid and coniferyl alcohol by conversion of eugenol using a recombinant strain of <i>Saccharomyces cerevisiae</i> (2013)

ABSTRACT We isolated an industrial strain of Saccharomyces cerevisiae 92411 able to convert coniferyl alcohol (2 g/l) into ferulic acid (1.8 g/l). To use eugenol as a substrate for the synthesis of natural ferulic acid, an optimized sequence of the Penicillium simplicissimum vaoA gene, encoding the flavoenzyme vanillyl‐alcohol oxidase (VAO), was expressed in the yeast 92411. To obtain a strong and stable expression of vaoA , an expression cassette flanked by Ty1 homologous sequences was constructed so the sequence encoding VAO could be integrated into various Ty1 loci of the host genome. The recombinant S. cerevisiae strain produced VAO. It synthesized ferulic acid directly from eugenol due to expression of the VAO activity and the natural ability of the strain to convert coniferyl alcohol into ferulic acid. In fermentation experiments, the strain produced up to 16.9 g/l of ferulic acid after 136 h. These results open new perspectives for the use of yeast biocatalysts in the biotechnological production of aromatic flavour from eugenol. Copyright © 2013 John Wiley & Sons, Ltd.
New Approach to Develop Optimized Sunscreens that Enable Cutaneous Vitamin D Formation with Minimal Erythema Risk (2016)

Sunscreens protect the skin against erythemal radiation (Eer). But at the same time they reduce the effective radiation dose (EVD) responsible for the formation of previtamin D in the skin. The paper describes a calculation method for optimizing the ratio EVD/Eer behind sunscreens e.g. with SPF 5, 15 and 30 respectively. Taking into account that a majority of people in industrialized countries suffer from a shortage in vitamin D even in summer time, the ratio Evd/Eer is a new and important criterion for the quality of sunscreens. Furthermore the exposure time tvd needed per day for forming the equivalent of the recommended amount of 2000 IU of vitamin D per day for skin type 2 is estimated when sunscreens with different filter compositions are used. In vitro experiments show a significant increase of the conversion of 7-dehydrocholesterol (7-DHC) to previtamin D when exposed to artificial solar radiation behind an experimental sunscreen optimized for previtamin D production compared to a commercial sunscreen having the same SPF.
Design and testing of a controllable miniature jumping robot (2010)

Mobile sensors with jumping ability provide several advantages compared with the traditional wheeled sensors such as ability to move in rugged terrain. A controllable jumping robot for this purpose is described in this paper. The robot has dimension about 9.5cm × 9cm × 3cm and weighs 54.1 grams. It can perform the jumping process continuously. This paper focuses on the mechanisms to achieve such a continuous jumping ability, including the jumping mechanism, energy store and release mechanism, and self-righting mechanism. Detail implementation and experimental results are also given in this paper. It is shown that with a 75° takeoff angle, the robot can jump about 20cm in height.
Diffusion bonding of Al–Li alloys (1992)

AbstractMethods for diffusion bonding of Al–Li alloys in the solid state and via a transient liquid phase are described and the factors that affect bond quality are discussed. Bond shear strength values at room temperature and peel strength values at room temperature and at superplastic forming temperatures are compared. The possibility of combining diffusion bonding with superplastic forming to manufacture multiple sheet structures is considered. It is concluded that under the most favourable processing conditions and on a small scale, combined diffusion bonding and superplastic forming of Al–Li 8090 alloy is now possible. Future developments will involve the optimisation of the process for cost effective commercial applications.MST/1608
Pulse Sharpening with Metal-Oxide Bulk Switching Devices (1976)

Nanomaterials constitute novel and interesting matrices for enzyme immobilization. While their high surface to volume ratio is an obvious advantage, their Brownian motion can impact the behavior of enzymes immobilized on these matrices. Carbon nanotubes, superparamagnetic nanoparticles, and mesoporous materials constitute some important classes of matrices. Such immobilized enzyme systems have been used in both aqueous and low water media for biocatalysis and resolution of racemates. This overview examines the behavior of enzymes immobilized on nanomaterials and discusses the results reported with such biocatalyst preparations.
Monolithic three-dimensional integrated circuits using carbon nanotube FETs and interconnects (2009)

We experimentally demonstrate, for the first time, monolithic three-dimensional integrated circuits consisting of multiple (up to three) layers of monolithically integrated circuits consisting of carbon nanotube field-effect transistors (CNFET) circuits and carbon nanotube (CNT) interconnects. These experimental demonstrations are made possible through a low-temperature (≪ 250°C) process, presented in this paper, for monolithic three-dimensional integration of CNFETs and CNT interconnects. Such a low-temperature process is enabled by low-temperature wafer-scale transfer of CNTs which decouples high-temperature CNT growth from low-temperature monolithic 3D integration.
Flexible stamp for nanoimprint lithography (2005)

The design, fabrication and performance of a flexible silicon stamp for homogenous large area nanoimprint lithography (NIL) are presented. The flexible stamp is fabricated by bulk semiconductor micro machining of a 4-inch silicon wafer and consists of thick anchor like imprint areas connected by membranes. The bending stiffness difference between the imprint areas and the membranes ensures that the deformation of the stamp during the imprint process mainly takes place in the membranes, leaving the imprint structures unaffected. By this design the strong demand to the parallelism between stamp and substrate in the imprint situation is decoupled from the pressing tool and the wafer quality. The stamp consist of 1562 imprint areas (1 mm /spl times/ 1 mm) containing the patterns to be replicated. The imprinted patterns are characterized with respect to the imprint depth and the polymer residual layer thickness. It is found that within a 50 mm diameter the polymer residual layer thickness is 18.8 nm with a standard deviation of 6.6 nm.
Electro-acoustic transducer (1982)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Masana Ugaji, Hideo Suyama, Sadaaki Sakurai, Shigenori Yamaoka, Toshinaga Endo, Akinobu Kusuhara; Electro‐acoustic transducer. J. Acoust. Soc. Am. 1 January 1982; 71 (1): 244. https://doi.org/10.1121/1.387262 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAcoustical Society of AmericaThe Journal of the Acoustical Society of America Search Advanced Search |Citation Search
Simple Alkenes as Substitutes for Organometallic Reagents:  Nickel-Catalyzed, Intermolecular Coupling of Aldehydes, Silyl Triflates, and Alpha Olefins (2005)

A nickel-catalyzed method for the three-component coupling of alkenes (ethylene and alpha olefins), aldehydes, and silyl triflates is described, and this process represents the first catalytic method for coupling aldehydes and alkenes to give allylic alcohol derivatives. Conceptually, the alkene functions as a replacement for an alkenylmetal reagent.
Prostate carcinomas developing in transgenic rats with SV40 T antigen expression under probasin promoter control are strictly androgen dependent. (2001)

We have generated a transgenic rat with the SV40 T antigen under probasin promoter control, allowing prostate-specific gene expression. Males demonstrate atypical epithelial cell proliferation in the prostate from 4 weeks of age and develop prostate carcinomas at 100% incidence before they are 15 weeks old. Castration at 5 weeks of age was found to inhibit the prostate tumor formation completely, whereas testosterone propionate administration induced marked cell proliferation as well as microinvasion in prostate carcinomas. Castration at 20 weeks of age, after tumor development, even with testosterone propionate treatment, induced complete tumor involution within 5 weeks. To investigate the underling processes, sequential histological changes were monitored 1, 2, 3, 7, 14, and 21 days after castration. At days 1-3, many apoptotic bodies and inflammatory cells, including foam cells, were observed, and clear glandular structures were no longer evident in the tumors. Seven days after castration, most glands were involved, and nuclei of the cells did not show atypia. After 14 and 21 days, only atrophic glands were observed. During this process, expression of caspase 3, caspase 6, BAX, bcl-x, TRPM-2, and MMP7 genes was apparently increased. Comparison of the gene expression profile between a prostate carcinoma in a transgenic animal and a normal prostate of a wild-type rat by a cDNA array technique was also conducted. The results suggested that our model is suitable to investigate mechanisms of carcinogenesis, including androgen dependence, involution, and apoptosis.
Infrared Visual Sensing Detection of Groove Width for Swing Arc Narrow Gap Welding (2022)

To solve the current problem of poor weld formation due to groove width variation in swing arc narrow gap welding, an infrared passive visual sensing detection approach was developed in this work to measure groove width under intense welding interferences. This approach, called global pattern recognition, includes self-adaptive positioning of the ROI window, equal division thresholding and in situ dynamic clustering algorithms. Accordingly, the self-adaptive positioning method filters several of the nearest values of the arc's highest point of the vertical coordinate and groove's same-side edge position to determine the origin coordinates of the ROI window; the equal division thresholding algorithm then divides and processes the ROI window image to extract the groove edge and forms a raw data distribution of groove width in the data window. The in situ dynamic clustering algorithm dynamically classifies the preprocessed data in situ and finally detects the value of the groove width from the remaining true data. Experimental results show that the equal division thresholding algorithm can effectively reduce the influences of arc light and welding fume on the extraction of the groove edge. The in situ dynamic clustering algorithm can avoid disturbances from simulated welding spatters with diameters less than 2.19 mm, thus realizing the high-precision detection of the actual groove width and demonstrating stronger environmental adaptability of the proposed global pattern recognition approach.
Novel drugs and diagnostic compositions for use in the treatment and diagnosis of neurodegenerative diseases or amyloid diseases [Neue Arzneimittel und diagnostische Zusammensetzungen fuer die Behandlung und Diagnose von neurodegenerativen Erkrankungen und Amyloid-Krankheiten] (2006)

The invention relates to drugs and diagnostic compositions and to the use of the active substances obtained for producing a drug or a diagnostic composition for use in the treatment or diagnosis of neurodegenerative diseases or amyloid diseases.
Hiding data in halftone image using Modified Data Hiding Error Diffusion (2000)

With the ease of distribution of digital images, there is a growing concern for copyright control and authentication. While there are many existing watermarking and data hiding methods for natural images, almost none can be applied to halftone images. In this paper, we proposed a novel data hiding method, Modified Data Hiding Ordered Dithering (MDHED) for halftone images. MDHED is an effective method to hide a relative amount of data while yielding halftone images with good visual quality. Besides, the amount of hidden data is easy to control and the security depends on the key not the system itself.