gebhart/patrepeval huggingface dataset:
A proposal for seamless handovers in GSM indoor wireless networks (2002)

We consider the evolution of a GSM-based indoor corporate network, where base transceiver stations (BTS) are IP end-points of the local area network (LAN). Multiplexing capabilities of real time protocol (RTP) payloads are exploited in order to transport efficiently TRAU (transcoding and rate adaptation unit) frames between each BTS and the BSC (base station controller)/access node. In this context, two RTP connections are used to transmit downlink TRAU frames to both current BTS and candidate BTS during handover execution, thus preventing typical loss of voice frames during this phase. This contributes to improving the quality of service (QoS) for voice communications in the selected environment. Signaling issues and assignments of resources to individual connections within a single RTP/UDP/IP connection in the described environment are also addressed. The proposed architecture also offers advantages for implementing tandem free operation (TFO) in a local environment.
Insights into Avian Influenza Virus Pathogenicity: the Hemagglutinin Precursor HA0 of Subtype H16 Has an Alpha-Helix Structure in Its Cleavage Site with Inefficient HA1/HA2 Cleavage (2012)

With a new serotype (H17) of hemagglutinin (HA) recently being discovered, there are now 17 serotypes (H1 to H17) of influenza A viruses in total. It is believed that HA is initially expressed as a precursor of HA0 and then cleaved into HA1 and HA2, forming a disulfide bond-linked complex, for its full function. Structural data show that a loop structure exists in the cleavage site between HA1 and HA2, and this flexible loop is crucial for the efficient cleavage of HA0. Here, the crystal structures of H16 (a low-pathogenicity avian influenza virus) in their HA0 form (H16HA0) have been solved at 1.7-Å and 2.0-Å resolutions. To our surprise, an α-helix element in the cleavage site which inserts into the negatively charged cavity with the key residue R329 hidden behind the helix was observed. In vitro trypsin cleavage experiments demonstrated inefficient cleavage of H16HA0 under both neutral and low-pH conditions. The results provide new insights into influenza A virus pathogenicity; both the relatively stable α-helix structure in the flexible cleavage loop and inaccessibility of the cleavage site likely contribute to the low pathogenicity of avian influenza A virus. Furthermore, compared to all of the HAs whose structures have been solved, H16 is a good reference for assigning the HA subtypes into two groups on the basis of the three-dimensional structure, which is consistent with the phylogenetic grouping. We conclude that in light of the current H16HA0 structure, the natural α-helix element might provide a new opportunity for influenza virus inhibitor design.
Prospective assessment of cardiac toxicity during a randomized phase II trial of doxorubicin and paclitaxel in metastatic breast cancer. (1997)

Since both doxorubicin and paclitaxel (Taxol; Bristol-Myers Squibb Company, Princeton, NJ) have substantial antitumor activity in advanced breast cancer, the combination of these two agents was a logical extension of the clinical development of paclitaxel. Early attempts used long infusions of both drugs, limiting the dose of both agents because of limiting gastrointestinal and myelosuppressive toxicity. Bolus doxorubicin combined with 3-hour infusion paclitaxel was reported to have dramatic antitumor activity, but clinically relevant cardiac toxicity in up to 20% of patients in two recent reports. In our current study the same schedules and doses of administration were used, limiting the total doxorubicin dose of 360 mg/m2. In-depth monitoring of cardiac function with noninvasive tests and endomyocardial biopsy were performed. Preliminary results suggest that, at these doses and schedule, the two-drug combination is safe, without unexpected toxicity. Limiting doxorubicin dose to 360 mg/m2 limits cardiac toxicity to levels expected from single-agent doxorubicin at similar cumulative doses.
The Magnitude and Challenge of False-Positive Newborn Screening Test Results (2000)

The magnitude of false-positive results generated in newborn screening programs, particularly for congenital endocrinopathies, presents a great challenge for future improvement of this important public health program. Attention must be given to improved laboratory tests, use of more specific markers, and better risk communication for families of patients with false-positive test results.
Circulating microRNA-375 as biomarker of pancreatic beta cell death and protection of beta cell mass by cytoprotective compounds (2017)

These findings show the potential use of serological miR-375 measurements to evaluate the beta cytoprotective effect of (potential) antidiabetic drugs in vivo.
Classification and interaction in random forests (2018)

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences.
Research on Human-Friendly Robot Motions : Motion of a Robot Holding Out an Object to a Human (1998)

This paper examines human-friendly motions of a robot holding out an object to a human. The motion parameters which give humans various impressions are discussed and their human-friendly values are analyzed using the rating scale method. First, we investigated the velocity pattern of the robots'holding out motion. Experimental results show that the bell-shaped velocity pattern with velocity peak in the front of the movement time is one of human-friendly. Second, we investigated the influences of maximum velocity value. Experimental results show that appropriate values exist and appropriate values for females are smaller than males. Third, we investigated the desirable position to which the robot should hold out the object. Experimental results show that the position should be chosen so that the manipulability measure of human two-link arm becomes small.
Vehicle Risk Assessment and Control for Lane-Keeping and Collision Avoidance at Low-Speed and High-Speed Scenarios (2018)

This paper examines a symbolic numerical approach to optimize a vehicles track for autonomous driving and collision avoidance. The new approach uses the classical cost function definition incorporating the essential aspects of the dynamic state of the vehicle as position, orientation, time sampling, and constraints on slip angles of tires. The optimization processes minimize the cost function and simultaneously determine the optimal track by varying steering and breaking amplitudes. The current velocity of the vehicle is limited to a maximal velocity, thus, allowing a stable search of the optimal track. The parametric definition of obstacles generates a flexible environment for low and high speed simulations. The minimal number of influential optimization variables guarantees a stable and direct generation of optimal results. By the current new approach to control a vehicle on an optimal track, we are able to autonomously move the vehicle on an arbitrary track approximated by low order polynomials. The optimization approach is also able to deal with a variety of different obstacles and the corresponding optimal smooth obstacle path. The computations demonstrate the effective control of a four wheel vehicle in normal operation and exceptional obstacle avoidance with continuously differentiable obstacle avoidance tracks. Simulation tests are done using vehicles velocities of 3, 6, 7.6, 10, 12, and 18 m/s. At higher vehicles velocities, a mathematical-only approach is not sufficient and a mechanical intervention for tires is needed as a complimentary part to control the slip angle. The results shows that the cost function reached a considerably high average convergence-to-zero rate success in most of the tested scenarios.
Compatibilization of low‐density polyethylene/plasticized starch blends by reactive compounds and electron beam irradiation (2008)

Abstract Blends based on various compositions of low‐density polyethylene (LDPE) and plasticized starch (PLST) were prepared by melt extrusion and molding in the form of sheets under hot press. The rheology properties during mixing were studied in terms of torque and temperature against mixing time. The structural properties of LDPE/PLST blends before and after electron beam irradiation was characterized by IR spectroscopy, tensile mechanical testing, and scanning electron microscopy (SEM). The torque‐time curves during the mixing process showed that the values of torque in the first region of mixing for pure LDPE or LDPE/PLST blends are higher in the presence of the compatibilizer PEMA than that in the presence of EVA. In addition, the stability of mixing was attained after a short time in the presence of PEMA. The IR spectroscopy suggests that the compatibilization by EVA and PEMA compounds proceeds through the formation of hydrogen bonding during mixing and this compatibility was improved after electron beam irradiation. The stress–strain curves of pure LDPE and its blends with PLST showed the behavior of tough polymers with yielding properties. The SEM micrographs of the fracture surfaces give supports to the effect of EVA and PEMA as compatibilizers and the effect of electron beam irradiation. POLYM. COMPOS., 2008. © 2008 Society of Plastics Engineers
Mental Stressor: Psychological Value of Social Distancing inCOVID-19 (2021)

The COVID-19 pandemic is still quickly seething around the world. Despite the fact that researchers all throughout the planet are ceaselessly chipping away at fostering a protected and powerful COVID-19 immunization, with the freak profoundly contagious strain, it will require 90% of the populace to be inoculated to arrive at group invulnerability, citing Dr. Manoj Jain, an irresistible illness doctor in Memphis. Before we arrive at this point current pandemic control actually needs equal procedures, for example, social separating, cleanliness and contact following (Among the variation control procedures, social separating has given the foundation of controlling the uncontrolled spread of the COVID during the severest occasions of worldwide episode and it ought to be irregularly applied as a vital system at whatever point inconsistent territorial or occasional resurgence occurs).
Cloning of a chromosomal α-amylase gene from Bacillus stearothermophilus (1991)

We have cloned and sequenced a gene for a heat-stable alpha-amylase from a natural isolate of Bacillus stearothermophilus. Previously, it had been shown that B. stearothermophilus amylase genes may be harboured on indigenous plasmids. We have found that our isolate harbours the amylase gene only on the chromosome and not on its indigenous plasmid.
Recursive autoregressive spectral estimation by minimization of the free energy (1992)

A digital signal processing technique applicable to power spectrum estimation, designated as the minimum free energy method, is described. With no a priori model assumption and no attempt to extract special features such as sinusoids, one can obtain high resolution even with high noise contamination of the measured signal. The technique is demonstrated by modification of the Burg recursive method of spectral analysis. A recursive minimum free energy method in which the reflection coefficient is chosen at each step is proposed for minimizing the free energy (the Burg energy measure minus the product of a temperature and an information entropy). The method produces a spectral estimator more impervious to high noise contamination than the Burg method and diminishes the Burg tendency to produce spurious peaks.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Effect of layered double hydroxide on the flame retardancy of intumescent flame retardant thermoplastic polyurethane composites prepared by selective laser sintering (2022)

Abstract Presently, layered double hydroxides (LDHs) are pervasively adopted as part of flame retardant polymer composite materials due to its favorable synergism effect with certain flame retardants. In addition, it is environmentally friendly. Meanwhile, selective laser sintering (SLS) is a powder‐based three‐dimensional (3D) printing technology, providing a novel path to manufacturing polymer composite materials with complex shapes. In this research, flame retardancy of thermoplastic polyurethane (TPU) was enhanced based on LDHs and intumescent flame retardant (IFR). Being prepared by SLS technology. First, TPU composite powders based on LDHs and IFR were obtained using a two‐stage mixing method. Morphology analysis revealed that IFR and LDHs were dispersed uniformly in TPU powder. Subsequently, flame retardant TPU composites were prepared with TPU composite powders using the SLS process under appropriate 3D printing parameters, thereby enabling flame retardant TPU parts to be obtained. With 23 wt% IFR and 2 wt% LDHs filler, the limiting oxygen index of TPU composite was reached to 31.7%, while passing the UL‐94 V‐0 level during the vertical burning test. The cone calorimeter test showed that the heat release rate, smoke production rate, as well as production of carbonic oxides, all decreased significantly following the addition of LDHs. Thermogravimetric analysis indicated that LDHs and IFR were characterized by a favorable synergism effect, with the TPU/23IFR/2LDHs possessing good thermal stability. Char residue analysis, including SEM, energy dispersive X‐ray, Fourier transform infrared, and Raman spectra, further testified that a synergism effect existed between LDHs and IFR in the TPU composite. Overall, in this study the TPU composites fabricated by SLS technology exhibited excellent flame retardant ability.
An Empirical Study on Voice-Enabled Web Applications (2006)

Although most users access Web applications using Web browser interfaces, pervasive computing offers new ways of accessing Internet applications from any device at any location. Pervasive computing technology impacts consumer attitudes, and the authors studied consumers' acceptance rate toward new pervasive interfaces using various attributes and factors. The study was undertaken in Taiwan, with the cellular phone chosen as the pervasive device for accessing an Internet application prototype--a voice-enabled Web system--through voice user interface technology. The study result showed that Handling was the most important factor in using a voice-enabled Web system. The article's findings can help with the design and
Analysis of New Education Technology method as Innovation and Entrepreneurship System in the Teaching-learning Process at the University of Tijuana, B.C., Mexico (2023)

A relevant investigation was made to evaluate the methods used in a high school of the Tijuana city, located in the northwest of the Mexican Republic and is a border city, having a commercial and educative treatments with the California State of the United States of America (USA), sending and receiving students to increase the scholar yielding. This is important because can have more specialized knowledge and skills to when finish his professional studies of the university and go to works in industrial, commercial, health and other type of jobs, can solve fast and efficient complicated situations that sometimes persons with a lot experience can’t solve because need this specialized knowledge. In this scientific study made in 2022, was analyzed some tools of industry 4.0 as internet of things (IOT) to capacitate professors of some topics of mathematics topic using this innovation and entrepreneurship system to increase the capacity of teachers and with this the skills of students of a public university in this important city of Mexico
Coreference annotation guidelines (2009)

Summary These guidelines describe the principle of enriching texts from syntactically annotated corpora with coreference information. This information can be added manually or with a program like CESAC. This paper explains the different types of relationships used for coreference links. It sets out general guiding principles that can be used to determine which NPs should be linked to which other NPs or IPs. Furthermore, it illustrates which types of relationships are appropriate in which circumstances. These guidelines contain a decision tree that should help prospective annotators in their task.
Is the follow-up of patients operated on for gastric carcinoma of benefit to the patient? (1992)

Gastroesophageal reflux disease (GERD) represents a spectra of symptoms and of reflux damage to the esophagus. This reflux damage is due to a prolonged acid exposure of the esophagus arising from an imbalance between protective motility factors and aggressive acid secretory factors. Initially, patients may be managed by modifying their food intake and by supportive anti-gravity measures. However, many individuals will require drug therapy. Symptomatic relief can be achieved with pro-kinetic agents, antacids, sucralfate suspension, H2-receptor antagonists and H(+)-K+ ATPase pump blockers. There are limitations in the study design of experiments which have compared one agent with another. Accepting these design limitations, it would appear that pump blockers lead to higher rates of endoscopic healing than the use of standard doses of H2-receptor antagonists. However, higher doses of H2-receptor antagonists will likely give higher rates of symptomatic relief and endoscopic healing of GERD. Recurrence of symptoms and esophagitis occur in a high proportion of patients with GERD, and some patients may need to be considered for maintenance therapy.
Reactions of Doubly Tucked-In Permethyltitanocene with tert-Butanol and Propargyl Alcohol. The Crystal Structures of Unusual Hydrolytic Byproducts (2008)

Reactions of double tucked-in permethyltitanocene [Ti{η 3 :η 4 -C 5 Me 3 (CH 2 ) 2 }(η 5 -C 5 Me 5 )] ( 1 ) with tert -butanol or propargyl alcohol in toluene proceeded sluggishly even with excess of the alcohol and at elevated temperature. The alcoholysis of 1 with tert -butanol afforded [Ti(η 5 -C 5 Me 5 )(O t -Bu) 3 ] ( 3 ) as the major product and Ti(O t -Bu) 4 as the minor one. The other product of the alcoholysis was pentamethylcyclopentadiene. The only isolated crystalline product was the very minor hydrolytic byproduct [{Ti III (η 5 -C 5 Me 5 ) 2 }(μ-O){Ti IV (O t -Bu) 3 }] ( 2 ). The alcoholysis of 1 containing traces of LiI with HOCH 2 C≡CH, containing apparently more water than t -BuOH, gave an inseparable mixture of oily products from which several crystals of an unintended hydrolytic byproduct [{Ti(η 5 -C 5 Me 5 )(OCH 2 C≡CH)(μ-O)} 3 LiI] ( 4 ) were isolated. X-ray crystal structures of 2 and 4 were determined.
Thermal-ADI (2001)

Due to the dramatic increase of clock frequency and integration density, power density and on-chip temperature in high-end VLSI circuits rise significantly. To ensure the timing correctness and the reliability of high-end VLSI design, efficient and accurate chip-level transient thermal simulations are of crucial importance.
RELEASE OF NOREPINEPHRINE FROM NEURONS IN DISSOCIATED CELL CULTURES OF CHICK SYMPATHETIC GANGLIA VIA STIMULATION OF NICOTINIC AND MUSCARINIC ACETYLCHOLINE RECEPTORS (1978)

Abstract— Dissociated cell cultures of chick embryo sympathetic ganglia were incubated with [ 3 H]nor‐epinephrine ([ 3 H]NE) which was taken up and stored in reserpine‐sensitive sites. Exposure of the cultures to cholinergic agonists for 5 min intervals resulted in the releaseof a significant proportion (2–20%) of the intracellular stores of [ 3 H]NE. Studies with specific cholinergic agonists and antagonists indicated that release of [ 3 H]NE could be evoked by stimulation of either nicotinic or muscarinic receptors. Release evoked by both nicotinic and muscarinic agonists was totally blocked in the presence of 3 μM‐tetrodotoxin. thus indicating that release was mediated via active electrical responses. Release by both types of agonists was also blocked in the presence of elevated Mg 2+ or when free Ca 2+ was removed from the extracellular medium. These findings are consistent with the presence of a stimulus‐secretion coupling mechanism. Release evoked by nicotine was optimal in the presence of 1.2 mM‐Ca 2+ , whereas release evoked by the muscarinic agonist methacholine increased by about 2‐fold when the Ca 2+ concentration was decreased from 1.2 to 0.3 mM. The latter observation may be due to a lowered threshold for evocation of active responses at low concentrations of Ca 2+ . Finally, no evidence was observed for interaction between the two types of receptors. These findings (a)indicate that cultured chick sympathetic neurons possess functional nicotinic and muscarinic cholinergic receptors as well as the ability to release NE via a stimulus‐secretion coupling mechanism; (b) suggest that such cultures may be particularly useful for studying the molecular events which link stimulation of cholinergic receptors to neurotransmitter release; and (c) provide further evidence that muscarinic receptors may play aphysiological role in ganglionic transmission.
Virtual 3D planning and guidance of mandibular distraction osteogenesis (2006)

We present a system for 3D planning and pre-operative rehearsal of mandibular distraction osteogenesis procedures. Two primary architectural components are described: a planning system that allows geometric bone manipulation to rapidly explore various modifications and configurations, and a visuohaptic simulator that allows both general-purpose training and preoperative, patient-specific procedure rehearsal. We provide relevant clinical background, then describe the underlying simulation algorithms and their application to craniofacial procedures.
Current Emergency Diagnosis & Treatment (1985)

The number of textbooks that are dedicated to emergency medicine has proliferated in recent years in parallel with the number of physicians who are interested in this specialty. Such books range from how-to-do-it manuals on the left to physiologic esoterica on the right. By these standards, this book lies fairly far to the left. It is a pragmatic, comprehensive text filled with decision trees, lists, and tables. Therein lie both its strengths and weaknesses. On the one hand, it covers most areas of emergency medicine and provides one reasonable approach to these problems. However, because of its space restraints it does not provide much in-depth discussion or factual background to suggest alternate approaches to complex issues. A case in point is the ten-line section devoted to hypertensive crisis. Useful drugs are listed alphabetically with little guidance to their indications, selections, or contraindications in the presence of renal failure, encephalopathy, etc.
The Effects of SOM230 on Cell Proliferation and Adrenocorticotropin Secretion in Human Corticotroph Pituitary Adenomas (2006)

Corticotroph tumors express multiple SSTR subtypes. SOM230 significantly suppressed cell proliferation and ACTH secretion in primary cultures of human corticotroph tumors. These in vitro results support the hypothesis that SOM230 may have a role in the medical therapy of corticotroph tumors.