gebhart/patrepeval huggingface dataset:
Speech enabled shopping application using Microsoft SAPI (1996)

PCs are no longer a playground for a few computer freaks. They have changed from big pocket calculators to be used as everyday tools with seemingly unlimited options. In modern countries using a computer has become a basic requirement like reading and writing. The importance of digital information has already reached such an enormous level that many start-up companies and even corporations provide information largely digital. Also politicians around the world try to find their ways to a paperless e-Government. Obviously this is a positive progress because it means up to date information at any time and for everybody. But is this really accessible to everybody? People with disability such as visual impaired are often forgotten though the number of the elderly for who it's very hard to identify the screen text is already high and increasing continuously during the next decades. So it would be a real relief to have the option to use ears to listen to the contents and use voices to navigate and control the computer systems. Even if sometime it is for normal people, it would be more comfortable to work with speech enabled applications. Microsoft has designed an interface called SAPI (Speech Application Programming Interface) which supports dynamic speech input and output, and integrated it in its current operating system. With the API it is possible to develop speech enabled applications without caring about the details of synthesis and recognition. In this paper, a windows application ispresented to demonstrate the speech-enabled application using Microsoft SAPI.
Ferrimagnetism in manganese-rich gallium and aluminium spinels due to mixed valence Mn<sup>2+</sup>–Mn<sup>3+</sup> states (2018)

Stoichiometric (MnGa<sub>2</sub>O<sub>4</sub> and MnAl<sub>2</sub>O<sub>4</sub>) and Mn-rich (Mn<sub>1.3</sub>Ga<sub>1.7</sub>O<sub>4</sub> and Mn<sub>1.4</sub>Al<sub>1.6</sub>O<sub>4</sub>) spinels with a small inversion degree (0.14-0.21) were obtained via a co-precipitation route followed by calcination of the as-synthesized coprecipitates at 700-1000 °C under different gas atmospheres (air, N<sub>2</sub> or argon). In situ synchrotron XRD at elevated temperatures reveals the conditions for synthesizing phase-pure materials. The stoichiometry of the samples is confirmed by inductively coupled plasma optical emission spectrometry as well as by structure refinement of neutron diffraction data of phase-pure specimens. XANES characterization reveals the average oxidation state of manganese to be +2.2 and 2.3 in Mn<sub>1.3</sub>Ga<sub>1.7</sub>O<sub>4</sub> and Mn<sub>1.4</sub>Al<sub>1.6</sub>O<sub>4</sub> spinels, respectively. The mixed Mn<sup>2+</sup>-Mn<sup>3+</sup> valence states are responsible for the ferrimagnetic properties of Mn<sub>1.3</sub>Ga<sub>1.7</sub>O<sub>4</sub> and Mn<sub>1.4</sub>Al<sub>1.6</sub>O<sub>4</sub> samples below 48 and 55 K, respectively, as well as for a smaller optical bandgap when compared to stoichiometric spinels.
Handling mobility in IoT applications using the MQTT protocol (2015)

Connectivity clearly plays an important role in Internet of Things (IoT) solutions, and the efficient handling of mobility is crucial for the overall performance of IoT applications. Currently, the most widely adopted protocols for IoT and Machine to Machine (M2M) environments, namely MQTT, CoAP or LWM2M, are directly dependent on the TCP/IP protocol suite. This suite is highly reliable when using wired networks, but it is not the best solution in the presence of intermittent connections. In this work we provide a solution to improve MQTT with an emphasis on mobile scenarios. The advantage of the solution we propose is making the system more immune to changes in the point of attachment of mobile devices. This way we avoid IoT service developers having to explicitly consider this issue. Moreover, our solution does not need extra support from the network through protocols like MobileIP or LISP. The obtained results show that our proposal, based on intermediate buffering, guarantees that there is no information loss during hand-off periods due to node mobility; furthermore, based on discrete event simulation results, we determine the maximum number of sources and the required amount of buffers for a mobile node.
Conjugation of DM1 to anti-CD30 antibody has potential antitumor activity in CD30-positive hematological malignancies with lower systemic toxicity (2019)

An anti-CD30 antibody-drug conjugate incorporating the antimitotic agent DM1 and a stable SMCC linker, anti-CD30-MCC-DM1, was generated as a new antitumor drug candidate for CD30-positive hematological malignancies. Here, the <i>in vitro</i> and <i>in vivo</i> pharmacologic activities of anti-CD30-MCC-DM1 (also known as F0002-ADC) were evaluated and compared with ADCETRIS (brentuximab vedotin). Pharmacokinetics (PK) and the safety profiles in cynomolgus monkeys were assessed. Anti-CD30-MCC-DM1 was effective in <i>in vitro</i> cell death assays using CD30-positive lymphoma cell lines. We studied the properties of anti-CD30-MCC-DM1, including binding, internalization, drug release and actions. Unlike ADCETRIS, anti-CD30-MCC-DM1 did not cause a bystander effect in this study. <i>In vivo</i>, anti-CD30-MCC-DM1 was found to be capable of inducing tumor regression in subcutaneous inoculation of Karpas 299 (anaplastic large cell lymphoma), HH (cutaneous T-cell lymphoma) and L428 (Hodgkin's disease) cell models. The half-lives of 4 mg/kg and 12 mg/kg anti-CD30-MCC-DM1 were about 5 days in cynomolgus monkeys, and the tolerated dose was 30 mg/kg in non-human primates, supporting the tolerance of anti-CD30-MCC-DM1 in humans. These results suggest that anti-CD30-MCC-DM1 presents efficacy, safety and PK profiles that support its use as a valuable treatment for CD30-positive hematological malignancies.
Hybrid Transactional/Analytical Processing (2017)

The popularity of large-scale real-time analytics applications (real-time inventory/pricing, recommendations from mobile apps, fraud detection, risk analysis, IoT, etc.) keeps rising. These applications require distributed data management systems that can handle fast concurrent transactions (OLTP) and analytics on the recent data. Some of them even need running analytical queries (OLAP) as part of transactions. Efficient processing of individual transactional and analytical requests, however, leads to different optimizations and architectural decisions while building a data management system.
Dystrophin Gene Replacement and Gene Repair Therapy for Duchenne Muscular Dystrophy in 2016: An Interview (2016)

After years of relentless efforts, gene therapy has now begun to deliver its therapeutic promise in several diseases. A number of gene therapy products have received regulatory approval in Europe and Asia. Duchenne muscular dystrophy (DMD) is an X-linked inherited lethal muscle disease. It is caused by mutations in the dystrophin gene. Replacing and/or repairing the mutated dystrophin gene holds great promises to treated DMD at the genetic level. Last several years have evidenced significant developments in preclinical experimentations in murine and canine models of DMD. There has been a strong interest in moving these promising findings to clinical trials. In light of rapid progress in this field, the Parent Project Muscular Dystrophy (PPMD) recently interviewed me on the current status of DMD gene therapy and readiness for clinical trials. Here I summarized the interview with PPMD.
On the capacity of multiuser MIMO networks with interference (2008)

Maximizing the total mutual information of multiuser multiple-input multiple-output (MIMO) systems with interference is a challenging problem. In this paper, we consider the power control problem of finding the maximum sum of mutual information for a multiuser network with mutually interfered MIMO links. We propose a new and powerful global optimization method using a branch-and-bound (BB) framework, coupled with a novel reformulation-linearization technique (RLT). The proposed BB/RLT guarantees finding a global optimum for multiuser MIMO networks with interference. To reduce the complexity of BB/RLT, we propose a modified BB variable selection strategy to accelerate the convergence process. Numerical examples are also given to demonstrate the efficacy of the proposed solution.
Kinetics of the reactions of hydrogen, nitrogen, and hydrogen/nitrogen mixtures with molten lithium (1981)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTKinetics of the reactions of hydrogen, nitrogen, and hydrogen/nitrogen mixtures with molten lithiumMichael P. Gardner and M. M. NishinaCite this: J. Phys. Chem. 1981, 85, 16, 2388–2392Publication Date (Print):August 1, 1981Publication History Published online1 May 2002Published inissue 1 August 1981https://pubs.acs.org/doi/10.1021/j150616a019https://doi.org/10.1021/j150616a019research-articleACS PublicationsRequest reuse permissionsArticle Views190Altmetric-Citations17LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Spectral Clustering for Divide-and-Conquer Graph Matching (2014)

We present a bijective parallelizable seeded graph matching algorithm designed to match very large graphs. Our algorithm combines spectral graph embedding with existing state-of-the-art seeded graph matching procedures. We theoretically justify our approach by proving that modestly correlated, large stochastic block model random graphs are correctly matched utilizing very few seeds through our divide-and-conquer procedure. Lastly, we demonstrate the effectiveness of our approach in matching very large graphs in simulated and real data examples. 1
Gaussian process regression flow for analysis of motion trajectories (2011)

Recognition of motions and activities of objects in videos requires effective representations for analysis and matching of motion trajectories. In this paper, we introduce a new representation specifically aimed at matching motion trajectories. We model a trajectory as a continuous dense flow field from a sparse set of vector sequences using Gaussian Process Regression. Furthermore, we introduce a random sampling strategy for learning stable classes of motions from limited data. Our representation allows for incrementally predicting possible paths and detecting anomalous events from online trajectories. This representation also supports matching of complex motions with acceleration changes and pauses or stops within a trajectory. We use the proposed approach for classifying and predicting motion trajectories in traffic monitoring domains and test on several data sets. We show that our approach works well on various types of complete and incomplete trajectories from a variety of video data sets with different frame rates.
Intrathecal noradrenaline has a dose‐dependent inhibitory or facilitatory effect on the flexion reflex in the rat (1987)

The effect of intrathecal noradrenaline (NA) on the hamstring flexion reflex to subcutaneous electrical shocks was examined in unanaesthetized, decerebrate, spinalized rats. Low doses of NA (200 ng and 2 micrograms) depressed and high doses (20 micrograms and 200 micrograms) facilitated the reflex. It is suggested that the primary effect of NA in the dorsal horn is inhibitory and in the ventral horn excitatory. Furthermore, the neurons mediating these effects are more sensitive to NA in the dorsal horn than in the ventral horn.
Protein absorption : development and present state of the subject (1990)

DEVELOPMENT OF THE SUBJECT Protein Absorption Before 1900 Protein Absorption in the 20th Century (1901-1920) Protein Absorption in the 20th Century (1921-1949) Protein Absorption in the 20th Century (1950- ) PRESENT STATE OF THE SUBJECT Protein Digestion and Absorption--Some General Considerations Absorption of Amino Acids Absorption of Peptides Absorption of Protein Digestion Products--Some Other Features Some Topics Related to Intestinal Transport of Peptides Appendix Notes References Index.
<title>Bayesian networks for satellite payload testing</title> (1999)

Satellite payloads are fast increasing in complexity, resulting in commensurate growth in cost of manufacturing and operation. A need exists for a software tool, which would assist engineers in production and operation of satellite systems. We have designed and implemented a software tool, which performs part of this task. The tool aids a test engineer in debugging satellite payloads during system testing. At this stage of satellite integration and testing both the tested payload and the testing equipment represent complicated systems consisting of a very large number of components and devices. When an error is detected during execution of a test procedure, the tool presents to the engineer a ranked list of potential sources of the error and a list of recommended further tests. The engineer decides this on this basis if to perform some of the recommended additional test or replace the suspect component. The tool has been installed in payload testing facility. The tool is based on Bayesian networks, a graphical method of representing uncertainty in terms of probabilistic influences. The Bayesian network was configured using detailed flow diagrams of testing procedures and block diagrams of the payload and testing hardware. The conditional and prior probability values were initially obtained from experts and refined in later stages of design. The Bayesian network provided a very informative model of the payload and testing equipment and inspired many new ideas regarding the future test procedures and testing equipment configurations. The tool is the first step in developing a family of tools for various phases of satellite integration and operation.
Distinction between normal and renal cell carcinoma kidney cortical biopsy samples using pattern recognition of1H magic angle spinning (MAS) NMR spectra (2000)

The technique of magic angle spinning (MAS) high resolution (1)H NMR spectroscopy applied to intact tissues provides excellent peak resolution and thus much biochemical information. The use of computer-based pattern recognition techniques to classify human renal cortex tissue samples as normal or tumour based on their (1)H MAS NMR spectra has been investigated. In this preliminary study of 22 paired control and tumour samples, exploratory data analysis using principal components based on NMR spectral intensities showed clear separation of the two classes. Furthermore, using the supervised method of linear discriminant analysis, based on individual data point intensities or on integrated spectral regions, it was possible to distinguish between the normal and tumour kidney cortex tissue with 100% accuracy, including a single example of a metastatic tumour from a primary lung carcinoma. A tumour sample from the collecting duct of the kidney showed a different NMR spectral profile, and pattern recognition indicated that this sample did not classify with the cortical tumours.
Development of a Software Tool Using Deterministic Logic for the Optimization of Cochlear Implant Processor Programming (2010)

It is argued that this novel tool allows a systematic approach focusing on outcome, reducing the fitting time, and improving the quality of fitting. It introduces principles of artificial intelligence in the process of CI fitting.
Variation of Formal Hydrogen-Bonding Networks within Electronically Delocalized π-Conjugated Oligopeptide Nanostructures (2014)

This photophysical study characterizes the generality of intermolecular electronic interactions present within nanomaterials derived from self-assembling oligopeptides with embedded π-conjugated oligophenylenevinylene (OPV) subunits stilbene and distyrylbenzene that in principle present two distinct β-sheet motifs. Two different synthetic approaches led to oligopeptides that upon self-assembly are expected to self-assemble into multimeric aggregates stabilized by β-sheet-like secondary structures. The target molecules express either two C-termini linked to the central OPV core (symmetric peptides) or the more common N-termini to C-termini polarity typical of natural oligopeptides (nonsymmetric peptides). Both peptide secondary structures were shown to form extended 1-D peptide aggregates with intimate intermolecular π-electron interactions. Differences in length of the π-conjugated OPV segments resulted in differing extents of intermolecular interactions and the resulting photophysics. The peptides containing the shorter stilbene (OPV2) units showed little ground state interactions and resulted in excimeric emission, while the longer distyrylbenzene (OPV3) peptides had different ground state interactions between adjacent π-conjugated subunits resulting in either perturbed electronic properties arising from exciton coupling or excimer-like excited states. Molecular dynamics simulations of nascent aggregate formation predict peptide dimerization to be a spontaneous process, possessing thermodynamic driving potentials in the range 2-6 kcal/mol for the four molecules considered. Antiparallel stacking of the peptides containing an OPV3 subunit is thermodynamically favored over the parallel orientation, whereas both arrangements are equally favored for the peptides containing an OPV2 subunit. This study validates the generality of peptide-π-peptide self-assembly to provide electronically delocalized supramolecular structures and suggests flexibility in peptide sequence design as a way to tune the material properties of π-conjugated supramolecular polymers.
Dissociated Vertical-Torsional Nystagmus in Vestibular Nucleus Lesion (2022)

Dissociated vertical-torsional nystagmus is a unique form of nystagmus characterized by conjugate torsional but disparate vertical components. It has been mainly reported in internuclear ophthalmoplegia or medial medullary lesion involving the medial longitudinal fasciculus (MLF). The patterns of the nystagmus may be explained by a disruption of vestibulo-ocular reflex pathways from vertical semicircular canal or utriculo-ocular reflex within the MLF, but it is debatable. We described a dissociated upbeat-torsional nystagmus in a patient with vestibular nucleus infarction without involvement of MLF.
Characterizing Gold Nanorods in Solution Using Depolarized Dynamic Light Scattering (2012)

The ability to custom-tailor surface plasmon resonances of metallic nanorods via their geometry has made nanorods a prominent platform for the design of novel nanomaterials with wide-ranging potential applications. Characterization of nanorod geometries within their native solution environments is essential for targeting nanorod properties to the specific application and for improved monitoring of nanorod synthesis. Here we use a custom-designed depolarized dynamic light scattering setup for measuring nanorod translational and rotational diffusion in situ. Using either straight cylinders or prolate ellipsoids as model geometries, we developed an approach to convert diffusion measurements directly into predictions of nanorod lengths and aspect ratios. Neither of these two geometrical models was able to properly reproduce real nanorod diffusion. Yet, these discrepancies mostly precluded reliable predictions of nanorod aspect ratios while derived nanorod lengths were within 10–20% of their values determined separately from transmission electron microscopy.
Metameric blacks and estimating reflectance (1994)

The smoothest reflectance function [ J. Opt. Soc. Am. A7, 1891 ( 1990)] is considered an estimate of the actual reflectance function with the same tristimulus values under the given illuminant. The estimate differs from the actual function by a so-called metameric black. The metameric black depends on a number of parameters that are inaccessible to the visual system and describes the uncertainty with which the visual system has to cope when illuminant-independent properties of reflectance are being predicted. Illuminant-independent properties of reflectance are determined that can be predicted with little uncertainty and that therefore can be calculated in good approximation from the estimate of the actual reflectance function. The result is an estimate of the property that is, by construction, almost independent of the illuminant and thus in principle is able to explain color constancy. Such a property, a weighted mean of reflectance yielding an achromatic variable, is constructed; the predictions are verified numerically; and the result is compared with experiment.
High HOMO levels and narrow energy band gaps of dithienogalloles (2015)

We synthesized air- and moisture-stable dithieno[3,2-<italic>b</italic>:2′,3′-<italic>d</italic>]galloles containing four-coordinated gallium atoms. The electron-donating properties and resonance effects of gallium atoms in dithienogalloles were demonstrated.
Mono-static CW Doppler Radar for Quantifying Respiratory Motion during PET/CT scans (2017)

Respiration-correlated waveforms (amplitude as a function of time) are the basis for motion-compensated PET reconstruction and also for gated or triggered CT scans. These are typically based on hardware attached to the patient's chest or abdomen, and are related to skin motions of a few mm have demonstrated that waveforms can instead be based on internal organ motions in the range 1 to 3 cm. CW Doppler radar was used at frequencies that penetrate deep into the body. First, only one antenna and a circulator were used, the mono-static approach. The antenna was designed to have higher directivity of radiation into the patient with reduced side-lobe radiation. The design included antenna loading by a human body. Second, the antennas' placement was optimized to reduce sensitivity to motions near the bed. EM field measurements indicated that the radar was a short-range device according to FCC specifications.