gebhart/patrepeval huggingface dataset:
The Duplicated Genes Database: Identification and Functional Annotation of Co-Localised Duplicated Genes across Genomes (2012)

The Duplicated Gene Database provides a list of co-localised and duplicated genes for several species with the available gene co-expression level and semantic similarity value of functional annotation. Adding these data to the groups of duplicated genes provides biological information that can prove useful to gene expression analyses. The Duplicated Gene Database can be freely accessed through the DGD website at http://dgd.genouest.org.
[Determination of alachlor residue in agricultural products]. (2007)

A method of the determination of alachlor residue in agricultural products was developed. Four different kinds of objects, corn, peanut, spinach, and orange were selected as representatives of main agricultural products. The sample was extracted with acetone-water (8:2, v/v). The extract was partitioned with dichloromethane, cleaned up by gel permeation chromatography (GPC) and solid phase extraction (SPE) in order to completely separate colorants from alachlor in the sample. The eluate was evaporated under vacuum to nearly dry and diluted with acetone to a definite volume. The solution was determined and identified by gas chromatography-mass spectrometry (GC-MS) using external standard method. The recoveries were 86.0%-98.2%, and relative standard deviations were 5.1%-6.7% with spiked at 0.010-0.200 mg/kg of alachlor in blank samples. The limit of quantification of this method was 0.010 mg/kg.
AR-PCA-HMM Approach for Sensorimotor Task Classification in EEG-based Brain-Computer Interfaces (2010)

We propose an approach based on Hidden Markov models (HMMs) combined with principal component analysis (PCA) for classification of four-class single trial motor imagery EEG data for brain computer interfacing (BCI) purposes. We extract autoregressive (AR) parameters from EEG data and use PCA to decrease the number of features for better training of HMMs. We present experimental results demonstrating the improvements provided by our approach over an existing HMM-based EEG single trial classification approach as well as over state-of-the-art classification methods.
A simple assay to study social behavior in<i>Drosophila</i>: measurement of social space within a group<sup>1</sup> (2011)

We have established a new simple behavioral paradigm in Drosophila melanogaster to determine how genes and the environment influence the behavior of flies within a social group. Specifically, we measure social space as the distance between two flies. The majority of Canton-s flies, regardless of their gender, are within two body lengths from each other. Their social experience affects this behavior, with social isolation reducing and mating enhancing social space respectively, in both males and females. Unlike several other social behaviors in the fly, including the formation of social groups themselves (a well-described behavior), social space does not require the perception of the previously identified aggregation pheromone cis-vaccenyl acetate. Conversely, performance of the assay in darkness or mutations in the eye pigmentation gene white increased social space. Our results establish a new assay for the genetic dissection of a fundamental mode of social interaction.
Mechanisms responsible for electrical properties of tissues and cell suspensions. (1994)

The electrical properties of tissues and cell suspensions are most unusual. They change with frequency in three distinct steps and their dielectric constants reach enormous values at low frequencies. We shall concentrate on the 'linear' properties as observed with applied fields less than 1 V/cm. The linear properties of interest include the dielectric constant epsilon and conductivity kappa. Extensive measurements have been carried out over a broad frequency range extending from less than 1 Hz to many GHz. Observed frequency changes of these properties obey causality, i.e., the Kramers-Kronig relationships which relate changes of dielectric constants with conductivity changes. A number of mechanisms have been identified which explain the observed data. These mechanisms reflect the various compartments of the biological material. These include membranes and their properties, biological macromolecules and fluid compartments inside and outside membranes. We summarize the mechanisms which contribute to the total frequency response.
The Influence of the Range of Electroactivity and Capacitance of Conducting Polymers on the Performance of Carbon Conducting Polymer Hybrid Supercapacitor (2003)

Hybrid electrochemical supercapacitors based on carbon and conducting polymers as negative and positive electrodes, respectively, have been investigated. Poly-(3-fluorinatedphenyl)thiophene and poly(ethylenedioxythiophene) derivatives showing various ranges of electrochemical activity and capacitance values were evaluated as positive electrodes. It was shown that the mass and capacitance of the polymers have a significant effect on the charge/discharge characteristics and performance of such hybrid electrochemical supercapacitors. The experimental conditions that should be used to obtain specific charge/discharge curves are presented. A linear charge/discharge curve can be obtained between 0 and 3 V when the weight of conducting polymer is larger than that of the negative carbon electrode. In contrast, a battery-like charge/discharge curve is recorded when a smaller conducting polymer weight, relative to that of the carbon electrode, is used. © 2003 The Electrochemical Society. All rights reserved.
Abduction and Deduction in Logic Programming for Access Control for Autonomic Systems (2005)

Autonomic communication and computing is the new paradigm for dynamic service integration over a network. An autonomic network crosses organizational and management boundaries and is provided by entities that see each other just as partners that need to collaborate with little known or even unknown parties. Policy-based network access and management already requires a paradigm shift in the access control mechanism: from identity-based access control to trust management and negotiation, but even this is not enough for cross-organizational autonomic communication. For many services no autonomic partner may guess a priori what will be sent by clients and clients may not know a priori what credentials are demanded for completing a service, which may require the orchestration of many different autonomic nodes. To solve this problem we propose to use interactive access control: servers should be able to get back to clients asking for missing or excessing credentials, whereas the latter may decide to supply or decline requested credentials and so on until a ﬁnal decision is taken. This proposal is grounded in a formal model on policy-based access control. It identifies the formal reasoning services of deduction, abduction and consistency checking that characterize the problem. It proposes two access control algorithms for stateless and stateful autonomic services and shows their completeness and correctness.
Empirical Bayes hierarchical models for regularizing maximum likelihood estimation in the matrix Gaussian Procrustes problem (2006)

Procrustes analysis involves finding the optimal superposition of two or more "forms" via rotations, translations, and scalings. Procrustes problems arise in a wide range of scientific disciplines, especially when the geometrical shapes of objects are compared, contrasted, and analyzed. Classically, the optimal transformations are found by minimizing the sum of the squared distances between corresponding points in the forms. Despite its widespread use, the ordinary unweighted least-squares (LS) criterion can give erroneous solutions when the errors have heterogeneous variances (heteroscedasticity) or the errors are correlated, both common occurrences with real data. In contrast, maximum likelihood (ML) estimation can provide accurate and consistent statistical estimates in the presence of both heteroscedasticity and correlation. Here we provide a complete solution to the nonisotropic ML Procrustes problem assuming a matrix Gaussian distribution with factored covariances. Our analysis generalizes, simplifies, and extends results from previous discussions of the ML Procrustes problem. An iterative algorithm is presented for the simultaneous, numerical determination of the ML solutions.
Electrodeposited Ruthenium as an Electrical Contact Material A REVIEW OF ITS PROPERTIES AND ECONOMIC ADVANTAGES (1980)

The potential advantages of ruthenium plating are becoming increasingly appreciated in the electrical contact field. By comparison with rhodium, electrodeposited ruthenium is much less costly and possesses very similar properties of extremely high hardness and resistance to corrosion but with superior resistance to wear; while the dramatic increase in the price of gold has further emphasised the importance of evaluating its merits of low contact resistance and much
Motion Correction in Dual Gated Cardiac PET Using Mass-Preserving Image Registration (2011)

Respiratory and cardiac motion leads to image degradation in positron emission tomography (PET) studies of the human heart. In this paper we present a novel approach to motion correction based on dual gating and mass-preserving hyperelastic image registration. Thereby, we account for intensity modulations caused by the highly nonrigid cardiac motion. This leads to accurate and realistic motion estimates which are quantitatively validated on software phantom data and carried over to clinically relevant data using a hardware phantom. For patient data, the proposed method is first evaluated in a high statistic (20 min scans) dual gating study of 21 patients. It is shown that the proposed approach properly corrects PET images for dual-cardiac as well as respiratory-motion. In a second study the list mode data of the same patients is cropped to a scan time reasonable for clinical practice (3 min). This low statistic study not only shows the clinical applicability of our method but also demonstrates its robustness against noise obtained by hyperelastic regularization.
Muscle fibrillin deficiency in Marfan's syndrome myopathy (2003)

Abnormalities in fibrillin can be detected in muscle biopsies from patients with Marfan's syndrome who have myopathy. This pedigree, with a point mutation in FBN1, also draws attention to the potential for respiratory failure associated with myopathy.
Cartilage induction by controlled mechanical stimulation <i>in vivo</i> (1999)

To study mechanical control of tissue differentiation, we designed a new version of the previously described bone conduction chamber. The bone conduction chamber consists of a cylindrical titanium chamber for implantation in the rat tibia. It has tissue ingrowth openings at one end, located subcortically, and the other end protrudes into the subcutis. The newly developed load chamber has a mobile piston so that an external compressive load can be transferred to the tissue within the chamber. Sprague-Dawley rats had a regular bone conduction chamber implanted in one tibia and a load chamber implanted in the other. Mesenchymal tissue was allowed to grow into the chamber for 3 weeks before the mechanical loading was started. Thereafter, twice a day, 20 cycles of compressive load were applied with a frequency of 0.17 Hz to the load chamber. This was estimated to produce a compressive hydrostatic stress of 2 MPa. The chambers, harvested after 7 weeks of loading, all contained newly formed bone. The bone ingrowth distance into the chamber was decreased in the loaded specimens compared with the contralateral unloaded controls (p = 0.01). Instead, cartilage was found in the loaded chambers next to the piston. Beneath the cartilage was a dense bone plate under which a marrow cavity had formed. No cartilage was found in the unloaded controls, but the architecture of the bone and marrow cavity was similar to that of the loaded specimens. We conclude that this model allows load to be transmitted onto the ingrowing tissue and that the load parameters used cause this tissue to differentiate into cartilage close to the piston.
In-Phase Versus Out-of-Phase Distributed Antenna Systems for Wireless Handheld Devices (2012)

Hand loading usually degrades the performance of handset antennas. With the aim of providing a solution robust to the human presence, this paper discloses a distributed antenna system fed in-phase capable of mitigating undesirable hand loading effects while providing enhanced performance. The solution consists of a passive array of two resonant coplanar monopole antennas inspired in the Hilbert geometry. Input impedances of both monopoles are combined into a single input-output port through two transmission lines featuring equal phases. This combination allows not only improving the performance of the radiating system with respect to that attained by a single monopole antenna, but also providing a symmetric solution immune to the finger location. The solution is compared with a single monopole and a distributed antenna system fed out-of-phase. Simulated and measured results demonstrate that the proposed design is capable of providing operation in the communication standards GSM850/GSM900 as well as in the UHF part of the LTE-Advanced while maintaining the same electromagnetic performance with certain independence of the finger location.
Oncolytic adenovirus-mediated therapy for prostate cancer (2016)

Prostate cancer is a leading cause of cancer-related death and morbidity in men in the Western world. Tumor progression is dependent on functioning androgen receptor signaling, and initial administration of antiandrogens and hormone therapy (androgen-deprivation therapy) prevent growth and spread. Tumors frequently develop escape mechanisms to androgen-deprivation therapy and progress to castration-resistant late-stage metastatic disease that, in turn, inevitably leads to resistance to all current therapeutics, including chemotherapy. In spite of the recent development of more effective inhibitors of androgen-androgen receptor signaling such as enzalutamide and abiraterone, patient survival benefits are still limited. Oncolytic adenoviruses have proven efficacy in prostate cancer cells and cause regression of tumors in preclinical models of numerous drug-resistant cancers. Data from clinical trials demonstrate that adenoviral mutants have limited toxicity to normal tissues and are safe when administered to patients with various solid cancers, including prostate cancer. While efficacy in response to adenovirus administration alone is marginal, findings from early-phase trials targeting local-ized and metastatic prostate cancer suggest improved efficacy in combination with cytotoxic drugs and radiation therapy. Here, we review recent progress in the development of multimodal oncolytic adenoviruses as biological therapeutics to improve on tumor elimination in prostate cancer patients. These optimized mutants target cancer cells by several mechanisms including viral lysis and by expression of cytotoxic transgenes and immune-stimulatory factors that activate the host immune system to destroy both infected and noninfected prostate cancer cells. Additional modifications of the viral capsid proteins may support future systemic delivery of oncolytic adenoviruses.
On the use of BERT for Neural Machine Translation (2019)

Exploiting large pretrained models for various NMT tasks have gained a lot of visibility recently.
Characterizing the effects of nonlinear amplifiers on linear modulation for digital portable radio communications (1990)

The design and performance of linear modulation techniques and RF power amplifiers are discussed. Various types of power amplifier are used in the comparison, using simulation, of out-of-band radiation and power efficiency. The designs focus on high-frequency silicon bipolar power amplifiers suitable for low-power portable radio applications. Two different 4-QAM (4-level quadrature amplitude modulation) schemes are compared. Power efficiency as high as 40% can be achieved using a dynamically biased amplifier operating near saturation. The effects of nonlinear distortions from power amplifiers on adjacent channel interference as well as bit and block error rate performance are also investigated.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Application of a compact all solid-state laser system to the in situ detection of atmospheric OH, HO2, NO and IO by laser-induced fluorescence (2002)

A tuneable, high pulse-repetition-frequency, solid state Nd:YAG pumped titanium sapphire laser capable of generating radiation for the detection of OH, HO2, NO and IO radicals in the atmosphere by laser induced fluorescence (LIF) has been developed. The integration of the laser system operating at 308 nm into a field measurement apparatus for the simultaneous detection of hydroxyl and hydroperoxy radicals is described, with detection limits of 3.1 x 10(5) molecule cm(-3) (0.012 pptv in the boundary layer) and 2.6 x 10(6) molecule cm(-3) (0.09 pptv) achieved for OH and HO2 respectively (30 s signal integration, 30 s background integration, signal-to-noise ratio = 1). The system has been field tested and offers several advantages over copper vapour laser pumped dye laser systems for the detection of atmospheric OH and HO2 radicals by LIF, with benefits of greater tuning range and ease of use coupled with reduced power consumption, instrument footprint and warm-up time. NO has been detected in the atmosphere at approximately 1 ppbv by single photon LIF using the Alpha 2Sigma+ <-- Chi 2Pi1/2 (0,0) transition at 226 nm, with absolute concentrations in good agreement with simultaneous measurements made using a chemiluminescence analyser. With some improvements in performance, particularly with regard to laser power, the theoretical detection limit for NO is projected to be approximately 2 x 10(6) molecule cm(-3) (0.08 pptv). Whilst operating at 445 nm, the laser system has been used to readily detect the IO radical in the laboratory, and although it is difficult to project the sensitivity in the field, an estimate of the detection limit is < 1 x 10(5) molecule cm(-3) (< 0.004 pptv), well below previously measured atmospheric concentrations of IO.
A 2.4 GHz Fractional-N Frequency Synthesizer With High-OSR ΔΣ Modulator and Nested PLL (2012)

This paper presents a nested-PLL architecture for a low-noise wide-bandwidth fractional-N frequency synthesizer. In order to reduce the quantization noise, operating frequency of ΔΣ modulator (DSM) is increased by using an intermediate output of feedback divider. A PLL which serves as an anti-alias filter is added to suppress noise aliasing caused by the divider. Prototype implemented in a 0.13 μm CMOS using ring VCOs achieves 26.3 dB of quantization noise suppression while consuming 15.2 mW and occupying 0.17 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> .
Question Generation with Minimal Recursion Semantics (2010)

Abstract. This paper proposes a semantics-based approach to question generation by transforming the Minimal Recursion Semantics representa-tion of declarative sentences to that of interrogative sentences. Sentences are first decomposed into smaller units on the semantic level. Then the semantic representation of target words are mapped to that of question words. Finally generation is realized through a linguistically deep English grammar. A prototype system is developed to verify the feasibility.
Adipose-derived stem cells-seeded bladder acellular matrix graft-silk fibroin enhances bladder reconstruction in a rat model (2017)

The unfavourable clinical outcomes of host cell-seeded scaffolds for bladder augmentation warrant improved bioactive biomaterials. This study aimed to examine the feasibility of adipose-derived stem cells (ASCs)-seeded bilayer bladder acellular matrix graft (BAMG)-silk fibroin (SF) scaffold in enhancing bladder reconstruction. Sprague Dawley rats were randomly divided into three groups: the BAMG-SF-ASCs group, the acellular BAMG-SF group and the cystotomy group. The BAMG-SF-ASCs group was sampled at 2, 4 and 12 weeks, and compared with the other groups at 12 weeks. In the BAMG-SF-ASCs group, the normal bladder contour was reformed similar to that in the cystotomy group, with abundant urothelium and smooth muscle regeneration, as well as a suitable scaffold degradation speed, and trivial fibrosis and inflammation. The ASCs seeded in BAMG-SF were maintained in the regenerated region during the 12-week experimental period and significantly enhanced the vessel density, nerve regeneration and bladder function compared with acellular BAMG-SF. In addition, the BAMG-SF-ASCs group presented elevated levels of SDF-1α, VEGF and their receptors, with an obvious increase in ERK 1/2 phosphorylation. BAMG-SF is a promising biomaterial for ASCs seeding to facilitate bladder augmentation and demonstrated an enhanced angiogenic potential possibly related to the SDF-1α/CXCR4 pathway via ERK 1/2 activation.
Symmetric connection problems and their solution by bidirectional search (1990)

A special search problem, the symmetric connection problem arising in passenger information systems, is defined formally. Bidirectional search is a natural solution strategy for this probiem. A modified ordered search algorithm SCO∗ is discussed. This algorithm is admissible if the heuristic estimate used is an oplimistic one.
Thermal Potential of Flat Evaporator Miniature Loop Heat Pipes for Notebook Cooling (2009)

Thermal management of laptops is an increasingly challenging task because of the high-heat flux associated with the microprocessors and the limited space available for the thermal control system inside the cabinet. In this paper, results are discussed from an investigation of two different designs of miniature loop heat pipes (mLHPs) for thermal control of compact electronic devices including notebooks. Two prototypes of mLHP, one with a disk-shaped evaporator, 30 mm diameter and 10 mm thick, and the other with a rectangular-shaped evaporator, 47 × 37 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> plan area and 5 mm thick, were designed to handle heat fluxes up to 50 W/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . In the disk-shaped evaporator, the compensation chamber was incorporated into the overall thickness of the evaporator, whereas for the rectangular-shaped evaporator a new design approach was used in which the compensation chamber was positioned on the sides of the wick structure such that it was coplanar with the evaporator section. The new design approach helped to decrease the thickness of the rectangular evaporator by 50% and therefore improved the ability to integrate miniature loop heat pipe technology into compact electronics enclosures. All of the thermal tests on mLHP prototypes were conducted in horizontal configurations. Total thermal resistance of the designed mLHPs was between 1 and 5° C/W. A comparative study of the mLHPs with conventional heat pipe and microchannel-based active liquid cooling systems has shown the superior heat transfer capability of the passively operating loop scheme for high-heat flux applications, and helped to classify mLHPs as candidates for laptop thermal management.
Genetic Inflammatory Factors Predict Restenosis After Percutaneous Coronary Interventions (2005)

Polymorphisms in 4 genes considered involved in the inflammatory reaction showed an association with TVR after PCI. Our results may contribute to the unraveling of the restenotic process. Given the explorative nature of this analysis, our results need to be replicated in other studies.