gebhart/patrepeval huggingface dataset:
Population Based Augmentation: Efficient Learning of Augmentation Policy\n Schedules (2019)

A key challenge in leveraging data augmentation for neural network training\nis choosing an effective augmentation policy from a large search space of\ncandidate operations. Properly chosen augmentation policies can lead to\nsignificant generalization improvements; however, state-of-the-art approaches\nsuch as AutoAugment are computationally infeasible to run for the ordinary\nuser. In this paper, we introduce a new data augmentation algorithm, Population\nBased Augmentation (PBA), which generates nonstationary augmentation policy\nschedules instead of a fixed augmentation policy. We show that PBA can match\nthe performance of AutoAugment on CIFAR-10, CIFAR-100, and SVHN, with three\norders of magnitude less overall compute. On CIFAR-10 we achieve a mean test\nerror of 1.46%, which is a slight improvement upon the current\nstate-of-the-art. The code for PBA is open source and is available at\nhttps://github.com/arcelien/pba.\n
Joint power control and signature design for time-reversal uplinks (2015)

In the time reversal division multiple access (TRDMA) system, the signal-to-noise ratio (SNR) is boosted and the interuser interference (IUI) is suppressed due to the temporal and spatial focusing effects of the time-reversal (TR) technique. However, since the focusing effects highly depend on the location-specific multipath profile, there exists a strong-weak focusing effect in the TRDMA uplink system where different users at different locations enjoy different level of focusing effects. In this paper, we formulate the strong-weak focusing effect in the multiuser TRDMA uplink system as a max-min signal-to-interference-noise ratio (SINR) balancing problem by means of joint power control and signature filter design. A novel two-stage adaptive algorithm that can guarantee the convergence is proposed. Numerical results show that our algorithm converges quickly, achieves a high energy-efficiency gain, and provides a performance guarantee to all users.
Tratamento das complicações clínicas decorrentes de intervenções neurocirúrgicas: Parte I: Infecções, complicações de procedimentos específicos, complicações sistêmicas, cognitivas e outras complicações (2008)

Resumo Objetivo: Apresentar as complicações neurocirúrgicas que ocorrem com grande freqüência; apesar dos esforços para preveni-las, algumas são inevitáveis. Método: Analisaram-se as principais complicações decorrentes de procedimentos neurocirúrgicos e os tratamentos específicos, baseados em revisão literária e em experiência própria. Conclusão: O tratamento médico dessas complicações pode ser transitório ou definitivo da causa subjacente, conforme a evolução clínica do paciente.
Formation of Fe<sub>2</sub>O<sub>3</sub> Microboxes with Hierarchical Shell Structures from Metal–Organic Frameworks and Their Lithium Storage Properties (2012)

Fe(2)O(3) microboxes with hierarchically structured shells have been synthesized simply by annealing Prussian blue (PB) microcubes. By utilizing simultaneous oxidative decomposition of PB microcubes and crystal growth of iron oxide shells, we have demonstrated a scalable synthesis of anisotropic hollow structures with various shell architectures. When evaluated as an anode material for lithium ion batteries, the Fe(2)O(3) microboxes with a well-defined hollow structure and hierarchical shell manifested high specific capacity (~950 mA h g(-1) at 200 mA g(-1)) and excellent cycling performance.
Two-stage erbium-doped fibre amplifiers suitablefor use in long-haulsoliton systems (1994)

The performance of 980 nm-pumped, two stage erbium-doped fibre amplifiers incorporating mid-amplifier components is investigated experimentally to determine their suitability as in-line repeaters for long haul soliton systems. Amplifiers are considered with counter-propagating pump and signal, as are devices pumped through WDMs located in the middle of the amplifier. These devices are found to offer significantly better noise performance than single stage designs.
Triple negative breast cancer: therapeutic and prognostic implications. (2011)

Triple negative breast cancers (TNBC) lack oestrogen receptor (ER), progesterone receptor (PR), nor over-express human epidermal growth factor receptor 2 (HER2). Epidemiologic studies demonstrate that women diagnosed with TNBC manifest a significantly different set of clinic-pathologic features and risk factors when compared to women with other subtypes of breast cancer. They are associated with poor prognosis, as defined by low five-year survival. To date many studies have examined the utility of traditional chemotherapy for the treatment of patients with TNBC and have confirmed the benefits of these agents in both the adjuvant and neoadjuvant settings. Targeted therapy options involving PARP1 and EGFR inhibition, are currently in different phases of development and will hopefully change the paradigm of how patients with TNBC are treated. The present commentary aims to summarize the latest findings on chemotherapy in the treatment of TNBC in both the neoadjuvant and adjuvant setting and explore the ongoing development of newer targeted agents.
<i>In vivo</i> dosimetry with optically stimulated dosimeters and RTQA2 radiochromic film for intraoperative radiotherapy of the breast (2013)

OSLDs produce results with an uncertainty comparable to other dosimeters near the surface of the applicator but the uncertainty increases to an unacceptably high level with distance from the applicator. RTQA2 radiochromic film is shown to be accurate both at the surface of the applicator and at distances of 1-2 cm.
A 60GHz line-of-sight 2x2 MIMO link operating at 1.2Gbps (2008)

We report first experimental results from a hardware prototype of a millimeter wave line-of-sight (LOS) 2x2 MIMO link. The proposed architecture uses antenna element spacing derived from the principles of diffraction limited optics to establish multiple parallel data channels. Operation at millimeter wave carrier frequencies reduces the antenna array size to reasonable dimensions. The proposed system architecture is scalable to larger one dimensional and two dimensional arrays supporting data rates ≫160Gbps. This paper presents the design and characterization of a hardware prototype 2x2 LOS MIMO link operating at 1.2Gbps.
Immunoglobulin G enzyme-linked immunosorbent assay using truncated nucleoproteins of Reston Ebola virus (2003)

We developed an immunoglobulin G (IgG) enzyme-linked immunosorbent assay (ELISA), using partial recombinant nucleoproteins (rNP) of Reston Ebola virus (EBO-R) and Zaire Ebola virus (EBO-Z). We examined the reaction of 10 sera from cynomolgus macaques naturally infected with EBO-R to each of the partial rNP in the IgG ELISA. All the sera reacted to the C-terminal halves of the rNP of both EBO-R and EBO-Z. Most of the sera reacted to the RdeltaC (amino acid (aa) 360-739), and Rdelta6 (aa 451-551) and/or Rdelta8 (aa 631-739) at a higher dilution than to the corresponding truncated rNPs of EBO-Z. The results indicate that this IgG ELISA is useful for detecting EBO-R specific antibody, and may have a potential to discriminate EBO-R infection from other subtypes.
Optimization of Deposition Parameters for α-Al2O3 Coatings by Double Glow Plasma Technique (2015)

The parameters to prepare -Al 2 O 3 coatings by double glow plasma technique were optimized to obtain dense and thick -Al 2 O 3 coatings on 316 L stainless steel at low temperature of 580 C. The parallel distance between the source electrode and the substrate, working pressure, source electrode voltage, and workpiece electrode voltage were designed by L9 Orthogonal array design. The thickness, microstructure, chemical composition and phase components of the sputter-deposited Al/-Al 2 O 3 coatings were analysed by means of 3-D non-contact surface profiler analysis, scanning electron microscopy equipped with energy dispersive X-ray spectrometry and glancing-angle X-ray diffraction, respectively. The results indicated that the parallel distance between the source electrode and the substrate played a dominant role in determining the thickness of the films. The coatings prepared at the optimum parameters exhibited a very dense, uniform, and compact microstructure without any cracks and defects. It was found that iron aluminide formed at the interface between the coatings and the substrates. The thickness of the coatings reached about 11.6 m at the deposition rate of ~64.4 nm min -1 . The oxidized coatings with the lowest porosity about 0.13 % had relative content of -Al 2 O 3 as high as 66.5 % when oxygen flow was 2 sccm.
Linear torque actuation using FPGA-controlled Magneto-Rheological actuators (2014)

In recent years, Magneto-Rheological (MR) clutches have been increasingly used for realizing compliant actuation. One difficulty in using MR clutches is the existence of nonlinear hysteretic behaviors between the input current and output torque of an MR clutch. In this paper, a new closed-loop, Field-Programable-Gate-Array (FPGA) based control scheme to linearize an MR clutch's input-output relationship is presented. The feedback signal used in this control scheme is the magnetic field acquired from hall sensors within the MR clutch. The FPGA board uses this feedback signal to compensate for the nonlinear behavior of the MR clutch using an estimated model of the clutch magnetic field. The local use of an FPGA board will dramatically simplify the use of MR clutches for torque actuation. The effectiveness of the proposed technique is validated using an experimental platform that includes an MR clutch as part of a compliant actuation mechanism. The results clearly demonstrate that the use of the FPGA based closed-loop control scheme can effectively eliminate hysteretic behaviors of the MR clutch, allowing to have linear actuators with predictable behaviors.
Palladium-Catalyzed Aromatic C–H Bond Nitration Using Removable Directing Groups: Regiospecific Synthesis of Substituted <i>o</i>-Nitrophenols from Related Phenols (2014)

A general and regiospecific transformation of substituted phenols into the related o-nitrophenols has been achieved via a three-step process involving the palladium-catalyzed chelation-assisted ortho-C-H bond nitration as the key step. In the process, 2-pyridinyloxy groups act as removable directing groups for the palladium-catalyzed ortho-nitration of substituted 2-phenoxypridines, and they can be readily removed in the subsequent conversion of the resulting 2-(2-nitrophenoxy)pyridines into 2-nitrophenols.
Mouthcare in oral cavity cancer (1990)

Helen Roberts stresses the vital part that nurses play in maintaining oral hygiene in patients with head and neck cancer
Scaffold Tailoring by a Newly Detected Pictet–Spenglerase Activity of Strictosidine Synthase: From the Common Tryptoline Skeleton to the Rare Piperazino-indole Framework (2011)

The Pictet-Spenglerase strictosidine synthase (STR1) has been recognized as a key enzyme in the biosynthesis of some 2000 indole alkaloids in plants, some with high therapeutic value. In this study, a novel function of STR1 has been detected which allows for the first time a simple enzymatic synthesis of the strictosidine analogue 3 harboring the piperazino[1,2-a]indole (PI) scaffold and to switch from the common tryptoline (hydrogenated carboline) to the rare PI skeleton. Insight into the reaction is provided by X-ray crystal analysis and modeling of STR1 ligand complexes. STR1 presently provides exclusively access to 3 and can act as a source to generate by chemoenzymatic approaches libraries of this novel class of alkaloids which may have new biological activities. Synthetic or natural monoterpenoid alkaloids with the PI core have not been reported before.
Accumulation of Colloidal Particles in Flow Junctions Induced by Fluid Flow and Diffusiophoresis (2017)

In flow channels, the fluid is expected to transport suspended particles unless the particles are too large or adhesive. New experiments show unexpected behavior---an accumulation of particles at flow junctions---when solutes are dissolved in the fluid.
Winograd-Based Real-Time Super-Resolution System on FPGA (2019)

With the rapid development of computer vision theory and visual display devices, High Frame Rate (HFR) and Ultra High Definition (UHD) techniques have received increasing attention from academic and industry. As they put high demands on performance and energy-efficiency, efficient customized hardware is required. In this paper, we propose an FPGA-based super-resolution system that enables real-time UHD upscaling in both high image quality and high frame rates. Our system crops each frame into blocks, measures their total variation values, and dispatches them accordingly to a neural network or an interpolation module for upscaling. We also propose a fast transposed convolution algorithm based on Winograd algorithm, which reduces the number of multiplications. Experimental results show that the proposed super-resolution system achieves superior performance in both reconstruction performance and efficiency over previous works.
Mutations and expression of the NFE2L2/KEAP1/CUL3 pathway in Chinese patients with lung squamous cell carcinoma (2016)

Considering the frequent mutations and abnormal expression, the NFE2L2/KEAP1/CUL3 pathway may play an important role in the therapy of Chinese patients with lung SqCC.
Deep long short-term memory adaptive beamforming networks for multichannel robust speech recognition (2017)

Far-field speech recognition in noisy and reverberant conditions remains a challenging problem despite recent deep learning breakthroughs. This problem is commonly addressed by acquiring a speech signal from multiple microphones and performing beamforming over them. In this paper, we propose to use a recurrent neural network with long short-term memory (LSTM) architecture to adaptively estimate real-time beamforming filter coefficients to cope with non-stationary environmental noise and dynamic nature of source and microphones positions which results in a set of timevarying room impulse responses. The LSTM adaptive beamformer is jointly trained with a deep LSTM acoustic model to predict senone labels. Further, we use hidden units in the deep LSTM acoustic model to assist in predicting the beamforming filter coefficients. The proposed system achieves 7.97% absolute gain over baseline systems with no beamforming on CHiME-3 real evaluation set.
Crystal Structure of the <i>Escherichia coli</i> Peptide Deformylase<sup>,</sup> (1997)

Protein synthesis in bacteria involves the formylation and deformylation of the N-terminal methionine. As eukaryotic organisms differ in their protein biosynthetic mechanisms, peptide deformylase, the bacterial enzyme responsible for deformylation, represents a potential target for antibiotic studies. Here we report the crystallization and 2.9 A X-ray structure solution of the zinc containing Escherichia coli peptide deformylase. While the primary sequence, tertiary structure, and use of coordinated cysteine suggest that E. coli deformylase belongs to a new subfamily of metalloproteases, the environment around the metal appears to have strong geometric similarity to the active sites of the thermolysin family. This suggests a possible similarity in their hydrolytic mechanisms. Another important issue is the origin of the enzyme's specificity for N-formylated over N-acetylated substrates. Based on the structure, the specificity appears to result from hydrogen-bonding interactions which orient the substrate for cleavage, and steric factors which physically limit the size of the N-terminal carbonyl group.
Effects of moxonidine on sympathetic nerve activity in patients with end-stage renal disease (2010)

In ESRD patients, low-dose MOX produced sustained and substantial reductions in sympathetic outflow without hemodynamically compromising them. We suggest that the inhibition of central sympathetic outflow may improve cardiovascular prognosis in ESRD.
Security in mobile and cordless telecommunications (2003)

Second generation mobile and cordless telephone systems, like GSM and DECT, provide for intersystem roaming and have integrated security features. These security features and the role played by smart cards in the implementation and management are discussed. The focus is on the security features provided in DECT because these are more comprehensive, and probably less widely known, then those provided in GSM. The method of authentication is identical to that used for authenticating subscribers accessing a GSM network. However, the DECT authentication mechanism includes an additional feature which is not provided within GSM. This feature provides for greater flexibility in the way authentication keys and authentication data may be managed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
PROTON MAGNETIC RESONANCE STUDIES OF ANGIOTENSIN II CONFORMATION: CHEMICAL SHIFTS FOR THE AROMATIC PROTONS OF SELECTED ANALOGUES IN DMSO—d6 AT 40 0MZ. (1987)

PROTON MAGNETIC RESONANCE STUDIES OF ANGIOTENSIN II CONFORMATION: CHEMICAL SHIFTS FOR THE AROMATIC PROTONS OF SELECTED ANALOGUES IN DMSO—d6 AT 40 0MZ. was published in 19. Porto Carras, Chalkidiki, Greece, Aug. 31–Sept. 5, 1986 on page 335.
Changes in Farr radioimmunoassay and EliA fluorescence immunoassay anti-dsDNA in relation to exacerbation of SLE (2013)

Measuring anti-dsDNA levels could support treatment adjustment during follow-up of patients with systemic lupus erythematosus (SLE). We investigated whether patients with exacerbations of SLE showed changes in anti-double-stranded DNA (anti-dsDNA) levels prior to the exacerbation using the Farr and EliA assay and examined which assay showed highest specificity and predictive value for exacerbations. Changes in anti-dsDNA of ≥ 25% prior to exacerbation were considered of clinical significance. Exacerbations were retrospectively abstracted from medical records. Eighteen of 48 patients showed one or more exacerbations. We found 22 exacerbations with complete lab work-up, all accompanied by ≥ 25% change in anti-dsDNA in one or both assays. Only 10 exacerbations showed concordant changes in anti-dsDNA in both assays. Changes in anti-dsDNA had a low predictive value for exacerbations of SLE, but the specificity of anti-dsDNA changes for patients with exacerbations was higher for EliA than Farr. We conclude that despite the limited relation between anti-dsDNA changes and exacerbations of SLE, anti-dsDNA testing could still support clinical decision making when used in the correct setting. We conclude that EliA is preferable over Farr for assaying anti-dsDNA during follow-up of patients with SLE because of higher specificity, less "hands-on" time and absence of radioactivity.
Therapeutic Hypothermia as a Neuroprotective Strategy in Neonatal Hypoxic-Ischemic Brain Injury and Traumatic Brain Injury (2012)

Evidence shows that artificially lowering body and brain temperature can significantly reduce the deleterious effects of brain injury in both newborns and adults. Although the benefits of therapeutic hypothermia have long been known and applied clinically, the underlying molecular mechanisms have yet to be elucidated. Hypoxic-ischemic brain injury and traumatic brain injury both trigger a series of biochemical and molecular events that cause additional brain insult. Induction of therapeutic hypothermia seems to ameliorate the molecular cascade that culminates in neuronal damage. Hypothermia attenuates the toxicity produced by the initial injury that would normally produce reactive oxygen species, neurotransmitters, inflammatory mediators, and apoptosis. Experiments have been performed on various depths and levels of hypothermia to explore neuroprotection. This review summarizes what is currently known about the beneficial effects of therapeutic hypothermia in experimental models of neonatal hypoxic-ischemic brain injury and traumatic brain injury, and explores the molecular mechanisms that could become the targets of novel therapies. In addition, this review summarizes the clinical implications of therapeutic hypothermia in newborn hypoxic-ischemic encephalopathy and adult traumatic brain injury.
Insecticide activity of surfactins and iturins from a biopesticide Bacillus subtilis Cohn (S499 strain). (2002)

Surfactin C14, surfactin C15, and iturin C15 are lipopeptides purified from Bacillus subtilis (S499 strain). They were incorporated to artificial diet of the fruit fly Drosophila melanogaster (Meigen) (Diptera, Drosophilidae) to assess their potential insecticide activity. Surfactins with long fatty acid chain (C14 and C15) showed insecticide effect on the fruit fly, D. melanogaster. On the contrary, iturin was not toxic to fruit fly D. melanogaster. At 100 ppm, surfactin C14 and C15 showed respectively 85.4 and 92.6% adults mortality after one-day exposure. F1 progeny fly emergence inhibition by C14 and C15 were respectively 79.8% and 91.3%. To check whether the biocide activity of lipopeptides was due to their surface-active properties, detergent Triton X100, SDS, CTAB and Tween 80 were tested. No adult mortality was recorded with the detergents but Triton X100 and SDS showed F1 progeny emergence inhibition similar to that of surfactins. We showed that there was a dose-response activity with surfactin C15.
Biophysics of nonablative dermal remodeling (2002)

This article explores the physics of nonablative skin remodeling as well as the histologic sequelae. Although there have been several studies of nonablative skin remodeling, the exact mechanisms of action and thus the optimum device-specific parameters are not yet known. The article is divided into a discussion of the physics of laser-tissue interactions, followed by a review of the types of devices used for nonablative skin remodeling, and the histologic findings that follow treatment.
The structures of the antitumour antibiotics, PD 114720 and PD 114721 (1984)

J. P. Schaumberg, G. C. Hokanson and J. C. French, J. Chem. Soc., Chem. Commun., 1984, 1450 DOI: 10.1039/C39840001450
8 x 20 Gb/s 315-km, 8 x 10 Gb/s 480-km WDM transmission over conventional fiber using multiple broad-band fiber gratings (1998)

We demonstrate eight-channel wavelength-division-multiplexed transmission at channel rates of both 20 Gb/s (315 km) and 10 Gb/s (480 km) using chirped fiber gratings with bandwidth of 6.5 mm for dispersion compensation of each 80-km conventional fiber span.