gebhart/patrepeval huggingface dataset:
Porcine Reproductive and Respiratory Syndrome Virus Infection at the Time of Porcine Circovirus Type 2 Vaccination Has No Impact on Vaccine Efficacy (2010)

Several porcine circovirus type 2 (PCV2) vaccines are now commercially available and have been shown to be effective at decreasing the occurrence of porcine circovirus-associated disease (PCVAD). Many herds are coinfected with PCV2 and porcine reproductive and respiratory syndrome virus (PRRSV). Some producers and veterinarians are concerned that if pigs are vaccinated for PCV2 at or near the time that they are typically infected with PRRSV, the efficacy of the PCV2 vaccine will be compromised. The impact of PRRSV on PCV2 vaccination is unclear and has not been investigated under controlled conditions. The objective of the present study was to determine whether the presence of PRRSV viremia has an effect on the efficacy of commercial PCV2 vaccinations. Three-week-old PCV2-negative conventional pigs with passively derived anti-PCV2 antibodies were either vaccinated with one of three commercial PCV2 vaccines or left nonvaccinated. A portion of the pigs were infected with PRRSV 1 week prior to PCV2 vaccination. To determine vaccine efficacy, a PCV2 challenge was conducted at 8 weeks of age. PCV2 vaccination, regardless of PRRSV infection status at the time of vaccination, was similarly effective in inducing an anti-PCV2 IgG response in the presence of maternally derived immunity and in protecting the pigs from PCV2 challenge, as determined by a reduction in the level of PCV2 viremia and a reduction in the prevalence and amount of PCV2 antigen in lymphoid tissues in vaccinated pigs compared to nonvaccinated pigs. The results indicate that acute PRRSV infection at the time of PCV2 vaccination has no adverse effect on PCV2 vaccine efficacy.
EUREKATAX: A Taxonomy for the Representation and Analysis of Qualitative Usability Test Data (2020)

Usability tests serve as an insightful source of feedback for product teams that want to deliver user-centered solutions and enhance the User Experience (UX) of their products and services. However, in many cases, formative usability tests in particular may generate a large volume of qualitative and unstructured data that need to be analyzed for decision making and further actions. In this paper, we discuss a more formal method of analyzing empirical data, using a taxonomy, namely Engineering Usability Research Empirical Knowledge and Artifacts Taxonomy (EUREKATAX). We describe how it can provide guidance and openness for transforming fuzzy feedback statements into actionable items. The main aim of the proposed method is to facilitate a more holistic and standardized process to empirical data analysis while adapting on the solution or context. The main contributions of this work comprise the: (a) definition of the proposed taxonomy which represents an organization of information structured in a hierarchy of four main categories (discover, learn, act, and monitor), eight sub-categories, and 52 items (actions/operations with their respective properties); (b) description of a method, that is expressed through the taxonomy, and adheres to a systematic but modular approach for analyzing data collected from the usability studies for decision making and implementation; (c) formulation of the taxonomy’s theoretical framework based on meticulously selected principles like experiential learning, activity theory: learning by expanding, and metacognition, and (d) extended evaluation into two phases, with 80 UX experts and business professionals, showing on the one hand the strong reliability of the taxonomy and high perceived fit of the items in the various classifications, and on the other hand the high perceived usability, usefulness and acceptability of the taxonomy when put into practice in real-life conditions. These findings are really encouraging, in an attempt to generate comparable, generalizable and replicable results of usability tests’ qualitative data analysis, thereby improving the UX and impact of software solutions.
A Unified Architecture for Doubly Fed Induction Generator Wind Turbines using a Parallel Grid Side Rectifier and Series Grid Side Converter (2007)

With steadily increasing wind turbine penetration, regulatory standards for grid interconnection have evolved to require that wind generation systems ride-through disturbances such as faults and support the grid during such events. Conventional modifications to the doubly fed induction generation (DFIG) architecture for providing ride-through result in limited control of the turbine shaft and grid current during fault events. A DFIG architecture in which the grid side converter is connected in series as opposed to parallel with the grid connection has shown improved low voltage ride through but poor power processing capabilities. In this paper a unified DFIG wind turbine architecture which employs a parallel grid side rectifier and series grid side converter is presented. The combination of these two converters enables unencumbered power processing and robust voltage disturbance ride through. A dynamic model and control structure for this unified architecture is developed. The operation of the system is illustrated using computer simulations.
Formulation and manufacture of pharmaceuticals by fluidized‐bed impregnation of active pharmaceutical ingredients onto porous carriers (2013)

A manufacturing method is presented for solid dosage forms using fluidized‐bed impregnation, which could eliminate many of the challenges during solid dosage manufacturing. The main difference between impregnation and dry blending is the placement of the active pharmaceutical ingredient (API) inside a porous carrier. This makes the final material flow properties independent of the physical properties of the API. The method consists of spraying an API solution in appropriate solvent onto a carefully chosen porous excipient in a fluidized state. The solution penetrates the porous carrier due to capillary forces and the solvent is evaporated soon after that. Impregnation and drying occur simultaneously, which makes this impregnation method suitable for continuous implementation. Carefully choosing the operating conditions allows impregnation to occur without introducing spray drying or spray coating of the API. The method is shown to generate an impregnated excipient with very high degree of homogeneity independent of the API loading. It is also shown that mild milling further improves blend uniformity to RSD levels below 1%, which are challenging to achieve using conventional techniques. On impregnation, the final physical properties of the material are seen to be mainly unchanged from the initial excipient properties. A study of this one‐step manufacturing method is described, using acetaminophen as the model drug and anhydrous calcium phosphate dibasic as the porous excipient. The experimental work presented establishes a proof of concept and investigates in detail blend uniformity, physical state of impregnated API, final physical properties of impregnated material, compressibility during tableting, capsule filling, and release profile of the final capsule formulation. It also discusses potential ways for drug release control and improvements using impregnation. © 2013 American Institute of Chemical Engineers AIChE J , 59: 4538–4552, 2013
Speaker independent speech recognition method using training speech from a small number of speakers (1992)

A novel speaker-independent speech recognition method, which registers speech uttered by a small number of speakers into a dictionary as model speech is presented. It is based on the hypothesis that movement of the vocal tract differs little among individuals when the same word is spoken. This idea leads to the conclusion that dynamic characteristics extracted from a small number of speaker's utterances are effective for speaker-independent speech recognition. A speech recognition method using model utterances in which similarity values of an input word are calculated by matching a small number of speakers' utterances with phoneme templates for speaker-independent recognition is described. When tested with 212 Japanese words, a word recognition rate of 95.8% was obtained. The evaluation of the noise robustness is also reported.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Infrared Time Domain Spectroscopy with Synchronized Frequency Combs (2010)

We describe a frequency-comb based system for time-domain spectroscopy in the near infrared. Our configuration implements synchronous, repetitive sampling of the time domain signature for real-time coherent signal averaging and improved signal-to-noise ratio.
Manipulating TLR pathways activated by oncolytic vaccinia virus elicits a potent immune response against tumors (VAC8P.996) (2014)

Abstract The immune response raised by oncolytic Vaccinia Virus after the infection and destruction of cancer cells is believed to be a key factor in the promising recent clinical results seen with these viruses. However, Vaccinia Virus primordially activates TLR2, which is associated with Th2 conversion and strong humoral responses. For cancer therapy, elicitation of cellular responses is thought to be more effective for the direct destruction of tumor cells. In this work, we switched the TLR response that a modified oncolytic Vaccinia Virus elicits. Firstly, we looked to activate the TLR3 pathway after infection with Vaccinia Virus, which is more associated with cellular responses. For this purpose, we constructed an oncolytic Vaccinia Virus that codifies for the TRIF protein, a key adaptor of the TLR3 pathway. The resulting virus increased the level of cytokines, chemokines and DAMPs released after infection, resulting in improved cytotoxicity in cancer cells and significantly enhanced therapeutic effects in mouse tumor models. Concurrently, we demonstrated that enzymatic deglycosylation of the surface of the virus is able to ablate the activation of cell surface TLRs, increasing the level of delivery and early viral gene expression in tumors in vivo. Finally, combination of both strategies demonstrated increased amounts of CTLs targeting the tumor, reduced levels of anti-viral neutralizing antibody and a further increase in antitumor activity in orthotopic mouse models.
False-negative results using Neisseria gonorrhoeae porA pseudogene PCR - a clinical gonococcal isolate with an N. meningitidis porA sequence, Australia, March 2011 (2011)

The gonococcal porA pseudogene is a popular target for in-house Neisseria gonorrhoeae PCR methods. With this study we present two novel findings: the first case of an N. gonorrhoeae porA pseudogene PCR false-negative result caused by sequence variation, and in the same organism, the first description of a clinical N. gonorrhoeae strain harbouring an N. meningitidis porA sequence.
Optical Monitoring of Film Thickness using Low-Coherence Reflectometry (1997)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text W. V. Sorin, S. Venkatesh, and B. L. Heffner, "Optical Monitoring of Film Thickness using Low-Coherence Reflectometry," in 12th International Conference on Optical Fiber Sensors, Vol. 16 of 1997 OSA Technical Digest Series (Optica Publishing Group, 1997), paper OThD1. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
New Nanocrystalline Cu/MnO<sub><i>x</i></sub> Catalysts Prepared from Supercritical Antisolvent Precipitation (2009)

Abstract Supercritical CO 2 is used as an antisolvent to precipitate out nanostructured homogeneous mixtures of Cu 2+ and Mn 3+ with crystallites of 10–20 nm in diameter. Following calcination, this material forms a crystalline tetragonal spinel, CuMn 2 O 4 , with a branched chainlike structure with a length of 160–200 nm and diameters of approximately 40 nm. This new material is more than twice as active per unit surface area as the conventionally prepared hopcalite catalysts for the oxidation of carbon monoxide. This is the first time that homogeneous mixed oxides have been formed using this method.
<title>Commercial manufacturing of vertical-cavity surface-emitting laser arrays</title> (1994)

Optoelectronic integrated circuits based on arrays of vertical- cavity surface emitting lasers (VCSELs) are evolving into functional chips enhancing the performance of fiber optic networks, optical data storage, laser printing and scanning, visual displays, and optoelectronic computing and other systems. This evolution involves the development of advanced manufacturing technology germane to packaged arrays of VCSELs comprising micro- optic lens arrays and interface electronics. In this paper we describe Photonics Research's LASE-ARRAY commercial manufacturing efforts. Specifically we will discuss commercial manufacturing advancements in molecular beam epitaxial growth, full-wafer processing, interface electronics, microoptic lens arrays, packaging and implementation of statistical process control. Yield and reliability will also be discussed. Last we discuss emerging applications for the LASE-ARRAY technology.
Architecture issues in multimedia storage systems (1997)

Next generation storage systems will need to provide support for both textual data and other types of multimedia data (e.g., images, video, audio). These two types of data differ in their characteristics, and hence require different techniques for their organization and management. In this paper, we provide an overview of 1) how storage systems can be architectured to support multimedia data, and 2) what are the main challenges in devising new algorithms to manage multimedia data. In order to provide rate guarantees for continuous media data, an admission control scheme must be employed that determines, for each client, whether there are sufficient resources available to service that client. To maximize the number of clients that can be admitted concurrently, the various system resources must be allocated and scheduled carefully. In terms of disks, we use algorithms for retrieving/storing data from/to disks that reduce seek latency time and eliminate rotational delay, thereby providing high throughput. In terms of main-memory, we use buffer management schemes that exploit the sequential access patterns for continuous media data, thereby resulting in efficient replacement of buffer pages from the cache.
Reverse Transcriptase in a Clinical Strain of <i>Escherichia coli</i> : Production of Branched RNA-Linked msDNA (1989)

Branched RNA-linked multicopy single-stranded DNA (msDNA) originally detected in myxobacteria has now been found in a clinical isolate of Escherichia coli. Although lacking homology in the primary structure, the E. coli msDNA is similar in secondary structure to the myxobacterial msDNA's, including the 2',5'-phosphodiester linkage between RNA and DNA. A chromosomal DNA fragment responsible for the production of msDNA was cloned in an E. coli K12 strain; its DNA sequence revealed an open reading frame (ORF) of 586 amino acid residues. The ORF shows sequence similarity with retroviral reverse transcriptases and ribonuclease H. Disruption of the ORF blocked msDNA production, indicating that this gene is essential for msDNA synthesis.
Accurate nonlocal theory for cascaded quadratic soliton compression (2007)

We study soliton compression in bulk quadratic nonlinear materials at 800 nm, where group-velocity mismatch dominates. We develop a nonlocal theory showing that efficient compression depends strongly on characteristic nonlocal time scales related to pulse dispersion.
Efficient androst-1,4-diene-3,17-dione production by co-expressing 3-ketosteroid-Δ<sup>1</sup>-dehydrogenase and catalase in<i>Bacillus subtilis</i> (2016)

This study showed the highest ADD productivity ever reported and provides a promising strain for efficient ADD production in the pharmaceutical industry.
Control of the Morphology of Dispersed Crystalline Polyester in a Toner For Low-Energy Fusing (2010)

In the electrophotographic printing market, a demand for printers with lower energy consumption has driven the need to design toners that are fusible at lower temperatures. It has been reported previously that the energy required for fusing a toner based on amorphous polyester (A-PES) can be reduced by including a crystalline polyester (C-PES) in the toner composition. The improved fusing ability of a C-PES-containing toner is attributed to the large drop in viscoelasticity of C-PES that occurs at its melting temperature. The fusing advantages provided by C-PES, however, can be accompanied by negative effects on the toner's storage stability and durability during printing. Thermal analysis of C-PES-containing toners reveals that the glass transition temperature (Tg) of a toner is dramatically reduced relative to the Tg of a similar toner without C-PES. The reduction in Tg caused by C-PES is linked to the loss in polymer crystallinity that occurs when C-PES is melt-mixed with A-PES during the toner kneading process. A key, therefore, to improving the storage stability and durability of a C-PES-containing toner is to achieve higher degrees of crystallinity in the toner. In this article, a thermal annealing process was investigated as a method to improve the storage stability and the durability of toner. The annealing treatment involved conditioning of the toner for controlled periods of time at temperatures between the Tg and the melting temperature of the toner. It was found that the annealing process promoted the recrystallization of C-PES in the toner, resulting in an increase in the Tg of the toner. It was revealed that the annealing process promoted the formation of nanometer-scale crystalline domains in the toner and that the crystalline domain size was dependent on the temperature at which the toner was annealed. Rheological evaluation of the annealed toners revealed that the melting temperature of C-PES-containing toner can be controlled by changing the temperature at which the toner is annealed. It was shown that the morphology of the C-PES domains in a toner can be controlled by annealing under the proper conditions to yield a toner that has good storage stability and durability simultaneously with low-energy fusing.
<title>Ferroelectric liquid crystalline polymers for display devices (Invited Paper)</title> (1992)

Ferroelectric liquid crystalline polymers (FLCP) were synthesized. These ferroelectricities were confirmed directly by measuring the polarization reversal currents and other electro- optical properties. The smectic layer structure of FLCP was also studied. A chevron structure similar to that of low molecular weight FLC was observed even in the FLCP cell. But the zigzag defects were not so sharp, which means it is easy to get a good orientation even in large area displays. We succeeded in making a FLCP display of 15 cm X 40 cm without any alignment layers.
Sugar, glyceryl, and (pyridylalkoxy)sulfinyl derivatives of methylcarbamate insecticides (1983)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSugar, glyceryl, and (pyridylalkoxy)sulfinyl derivatives of methylcarbamate insecticidesTeruomi Jojima, Mohamed A. H. Fahmy, and Tetsuo R. FukutoCite this: J. Agric. Food Chem. 1983, 31, 3, 613–620Publication Date (Print):May 1, 1983Publication History Published online1 May 2002Published inissue 1 May 1983https://pubs.acs.org/doi/10.1021/jf00117a035https://doi.org/10.1021/jf00117a035research-articleACS PublicationsRequest reuse permissionsArticle Views56Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
High Efficiency Solar-to-Hydrogen Conversion on a Monolithically Integrated InGaN/GaN/Si Adaptive Tunnel Junction Photocathode (2015)

H2 generation under sunlight offers great potential for a sustainable fuel production system. To achieve high efficiency solar-to-hydrogen conversion, multijunction photoelectrodes have been commonly employed to absorb a large portion of the solar spectrum and to provide energetic charge carriers for water splitting. However, the design and performance of such tandem devices has been fundamentally limited by the current matching between various absorbing layers. Here, by exploiting the lateral carrier extraction scheme of one-dimensional nanowire structures, we have demonstrated that a dual absorber photocathode, consisting of p-InGaN/tunnel junction/n-GaN nanowire arrays and a Si solar cell wafer, can operate efficiently without the strict current matching requirement. The monolithically integrated photocathode exhibits an applied bias photon-to-current efficiency of 8.7% at a potential of 0.33 V versus normal hydrogen electrode and nearly unity Faradaic efficiency for H2 generation. Such an adaptive multijunction architecture can surpass the design and performance restrictions of conventional tandem photoelectrodes.
Films Containing Optically Nonlinear Diacetylene Monomer (1993)

Solid films exhibiting nonlinear optical properties prepared as mixtures of poly(methyl methacrylate) with various amounts of diacetylene monomer called compound 1 in article, Synthesizing Diacetylenes With Nonlinear Optical Properties (MFS-26186). Useful as phase-conjugate mirrors in laser-beam communications and as optical switches in optical computers. This particular diacetylene monomer exhibits strong third-order nonlinear optical properties, both in pure form and in solution.
One-dimensional confinement of a nanosized metal organic framework in carbon nanofibers for improved gas adsorption (2011)

The loading of a Zn-terephthalate based MOF in the inner cavity as well as on the outer walls of a hollow carbon nanofiber (CNF) creates MOF@CNF hybrids. This hybrid ''MOF@CNF'' displayed improved thermal stability as well as gas adsorption compared to the individual counterparts.
Sulphated hyaluronic acids: a chemical and biological characterisation (1998)

This review focuses on the possibility of modifying hyaluronic acid by the insertion of sulphate groups in order to obtain heparin-like compounds with controllable properties. In particular, the physicochemical and biological behaviour of sulphated hyaluronic acid (HyalSx) with various degrees of sulphation and different molecular weights has been particularly investigated. The mobilization of endothelial cells was investigated by the use of copper(II) complexes with HyalSx and the results were compared with those from the corresponding complex with heparin. New materials containing HyalSxare proposed for biomedical applications. ©1998 SCI.