gebhart/patrepeval huggingface dataset:
Optically Transparent Microwave Polarizer Based On Quasi-Metallic Graphene (2015)

In this paper, we report on the engineering and the realization of optically transparent graphene-based microwave devices using Chemical Vapour Deposition (CVD) graphene whose sheet resistance may be tailored down to values below 30 Ω/sq. In particular, we show that the process was successfully used to realize and characterize a simple, optically transparent graphene-based wire-grid polarizer at microwave frequencies (X band). The availability of graphene operating in a quasi-metallic region may allow the integration of graphene layers in several microwave components, thus leading to the realization of fully transparent (and flexible) microwave devices.
HCV RNA Assay Sensitivity Impacts the Management of Patients Treated with Direct-Acting Antivirals (2014)

This study suggests that HCV viral load assay performance characteristics need to be taken into consideration when managing HCV patients with RGT. Further studies are required to determine whether a consensus HCV RNA level threshold can be established or whether HCV viral load assays with greater sensitivity can increase cure rates with RGT.
Comparison of Two Cyclosporine Formulations in Healthy Volunteers: Bioequivalence of the New Sang‐35 Formulation and Neoral (1998)

This study was conducted to establish bioequivalence between a newly developed oral cyclosporine formulation, Sang-35 (SangStat Medical Corp., Menlo Park, CA), and the microemulsion formulation Neoral (Novartis Pharmaceuticals, East Hanover, NJ). In a randomized, open-label, two-way crossover study, 36 fasted, healthy male volunteers received a single 500-mg cyclosporine dose formulated either as Sang-35 or Neoral. Mean are under the concentration-time curve to infinity (AUC0-infinity) for Sang-35 was 13,900 microg x hr/L compared with 14,000 microg x hr/L for Neoral, with a 90% confidence interval (CI) of 96% to 103% for the geometric mean ratio of the two formulations. Mean maximum concentration (Cmax) was 1,690 microg/L for Sang-35 and 1,700 microg/L for Neoral, with a 90% CI of 96% to 103%. Geometric mean ratios for both AUC0-infinity and Cmax were within the acceptance criteria for bioequivalence (80-125%). Additional studies showed no differences between Sang-35 and Neoral after high-fat meals (n = 19), in female volunteers (n = 25) and in black volunteers (n = 7). It is concluded that single doses of the oral cyclosporine formulations Sang-35 and Neoral are bioequivalent in healthy fasted subjects, after high-fat meals, in women, and in blacks.
Trivalent Chromium Pre-Treatment for Corrosion Protection of Aluminum Alloys - an Electrochemical Evaluation (1994)

Abstract A corrosion resistant chemical conversion coating on aluminum alloys was developed using a trivalent chromium bath. Electrochemical impedance spectroscopy and dc-polarization measurements were made to determine the nature of the surface films formed. The results showed a 10 to 100 fold increase in the polarization resistance of the surface films compared to the untreated aluminum alloy. These electrochemical results compared well with the corrosion behavior in salt spray tests. The trivalent chromium-treated surfaces showed no corrosion for up to 200 hours in 5% salt spray. A post-treatment with an oxidizer even further improved its resistance which almost doubled its corrosion protection.
Gait Recognition Using Image Self-Similarity (2004)

Gait is one of the few biometrics that can be measured at a distance, and is hence useful for passive surveillance as well as biometric applications. Gait recognition research is still at its infancy, however, and we have yet to solve the fundamental issue of finding gait features which at once have sufficient discrimination power and can be extracted robustly and accurately from low-resolution video. This paper describes a novel gait recognition technique based on the image self-similarity of a walking person. We contend that the similarity plot encodes a projection of gait dynamics. It is also correspondence-free, robust to segmentation noise, and works well with low-resolution video. The method is tested on multiple data sets of varying sizes and degrees of difficulty. Performance is best for fronto-parallel viewpoints, whereby a recognition rate of 98% is achieved for a data set of 6 people, and 70% for a data set of 54 people.
Role of Computed Tomography Voxel Size in Detection and Discrimination of Calcium and Iron Deposits in Atherosclerotic Human Coronary Artery Specimens (2009)

Clinical CT scanners cannot be expected to discriminate iron deposits from calcifications by their CT value alone in the arterial wall.
Property-specific witness graph generation for guided simulation (2001)

A practical solution to the complexity of design validation is semi-formal verification, where the specification of correctness criteria is done formally, as in model checking, but checking is done using simulation, which is guided by directed vector sequences derived from knowledge of the design and/or the property being checked. Simulation vectors must be effective in targeting the types of bugs designers expect to find rather than some generic coverage metrics. The focus of our work is to generate property-specific testbenches for guided simulation, that are targeted either at proving the correctness of a full CTL property or at finding a bug. This is facilitated by generation of a property-specific model, called a graph, which captures interesting paths in the design. Starting from an initial abstract model of the design, symbolic model checking, pruning, and refinement steps are applied in an iterative manner, until either a conclusive result is obtained or computing resources are exhausted. The witness graph is annotated with, e.g., state or transition priorities before testbench generation. The overall testbench generation flow, and the iterative flow for witness graph generation are shown.
Autonomous Indication of Mechanical Damage in Polymeric Coatings (2016)

High-resolution in situ autonomous visual indication of mechanical damage is achieved through a microcapsule-based polymeric material system. Upon mechanical damage, ruptured microcapsules release a liquid indicator molecule. A sharp color change from light yellow to bright red is triggered when the liberated indicator 2',7'-dichlorofluorescein reacts with the polymeric coating matrix.
Thermal casting process for the preparation of membranes (1985)

Disclosed is a method for providing anisotropic polymer membrane from a binary polymer/solvent solution using a thermal inversion process. A homogeneous binary solution is cast onto a support and cooled in such a way as to provide a differential in cooling rate across the thickness of the resulting membrane sheet. Isotropic or anisotropic structures of selected porosities can be produced, depending on the initial concentration of polymer in the selected solvent and on the extent of the differential in cooling rate. This differential results in a corresponding gradation in pore size. The method may be modified to provide a working skin by applying a rapid, high-temperature pulse to redissolve a predetermined thickness of the membrane at one of its faces and then freezing the entire structure.
A Human Breast Epithelial Cell Type with Stem Cell Characteristics as Target Cells for Carcinogenesis (2001)

Two types of human breast epithelial cells (HBEC) have been characterized. In contrast to Type II HBEC, which express basal epithelial cell phenotypes, Type I HBEC are deficient in gap junctional intercellular communication and are capable of anchorage-independent growth and of expressing luminal epithelial cell markers, estrogen receptors, and stem cell characteristics (i.e. the ability to differentiate into other cell types and to form budding/ductal organoids on Matrigel). A comparative study of these two types of cells has revealed a high susceptibility of Type I HBEC to immortalization by SV40 large T antigen, although both types of cells are equally capable of acquiring an extended life span (bypassing senescence) after transfection with SV40. The immortalization was accompanied by elevation of a low level of telomerase activity in the parental cells after mid-passage ( approximately 60 cumulative population doubling levels). Thus HBEC do have a low level of telomerase activity, and Type I HBEC with stem cell characteristics are more susceptible to telomerase activation and immortalization, a mechanism which might qualify them as target cells for breast carcinogenesis. The immortalized Type I HBEC can be converted to highly tumorigenic cells by further treatment with X rays (2 Gy x 2) and transfection with a mutated ERBB2 (also known as NEU) oncogene, resulting in the expression of p185(ERBB2) which is tyrosine phosphorylated.
Novel Enzymatic Method for the Production of Xylitol from<scp>D</scp>-Arabitol by<i>Gluconobacter oxydans</i> (2002)

Microorganisms capable of producing xylitol from D-arabitol were screened for. Of the 420 strains tested, three bacteria, belonging to the genera Acetobacter and Gluconobacter, produced xylitol from D-arabitol when intact cells were used as the enzyme source. Among them, Gluconobacter oxydans ATCC 621 produced 29.2 g/l xylitol from 52.4 g/l D-arabitol after incubation for 27 h. The production of xylitol was increased by the addition of 5% (v/v) ethanol and 5 g/l D-glucose to the reaction mixture. Under these conditions, 51.4 g/l xylitol was obtained from 52.4 g/l D-arabitol, a yield of 98%, after incubation for 27 h. This conversion consisted of two successive reactions, conversion of D-arabitol to D-xylulose by a membrane-bound D-arabitol dehydrogenase, and conversion of D-xylulose to xylitol by a soluble NAD-dependent xylitol dehydrogenase. Use of disruptants of the membrane-bound alcohol dehydrogenase genes suggested that NADH was generated via NAD-dependent soluble alcohol dehydrogenase.
Short‐ and Long‐Term Immune Responses of CD‐1 Outbred Mice to the Scrub Typhus DNA Vaccine Candidate: p47Kp (2005)

Orientia tsutsugamushi is an obligate intracellular bacterium that is the causative agent of scrub typhus. To develop an effective vaccine to prevent or ameliorate scrub typhus, knowledge of the protective immune response to O. tsutsugamushi needs to be ascertained. Our laboratory has demonstrated that the DNA vaccine vector pVR1012 carrying the O. tsutsugamushi Karp strain 47-kDa protein gene (p47Kp) consistently provides outbred mice protection against homologous challenge.
Regulation of the acid-labile subunit of the insulin-like growth factor complex in cultured rat hepatocytes. (1994)

The acid-labile subunit (ALS) is a glycoprotein that forms a ternary complex in serum with insulin-like growth factors and insulin-like growth factor-binding protein-3. This study investigates the regulation of ALS production, measured by RIA, and messenger RNA (mRNA) content, measured by Northern analysis, in primary rat hepatocyte monolayer cultures. Hepatocytes produced ALS at a linear rate over 48 h. Exposure to human GH (30 ng/ml) caused a maximum 2.2-fold stimulation of ALS production compared to that in control cultures, giving a rate of 200 ng/10(6) cells.48 h. ALS mRNA appeared as a predominant 2-kilobase band and increased 4-fold by administration of 30 ng/ml GH. Both dexamethasone and epidermal growth factor (EGF) inhibited ALS production, with maximal effects at 100 nM dexamethasone and 50 ng/ml EGF (both approximately 50% inhibition). ALS mRNA levels measured 24 or 48 h after dexamethasone addition were decreased 75-80% compared to the control value. A similar decrease in ALS mRNA was observed 24 h after EGF addition, but a second addition of EGF at 24 h was required to maintain this decrease for 48 h. This study demonstrates that rat hepatocytes secrete immunoreactive ALS under GH regulation, and that EGF and corticosteroid inhibit ALS production and mRNA levels. The quantitative discrepancies between ALS production rates and mRNA levels suggest that posttranscriptional events may have a role in ALS regulation.
Composite Nature of Layered Hybrid Perovskites: Assessment on Quantum and Dielectric Confinements and Band Alignment (2018)

Layered hybrid organic-inorganic perovskites (HOPs) have re-emerged as potential technological solutions for next-generation photovoltaic and optoelectronic applications. Their two-dimensional (2D) nature confers them a significant flexibility and results in the appearance of quantum and dielectric confinements. Such confinements are at the origin of their fascinating properties, and understanding them from a fundamental level is of paramount importance for optimization. Here, we provide an in-depth investigation of band alignments of 2D HOP allowing access to carriers' confinement potentials. 2D HOPs are conceptualized as composite materials in which pseudoinorganic and -organic components are defined. In this way, computational modeling of band alignments becomes affordable using first-principles methods. First, we show that the composite approach is suitable to study the position-dependent dielectric profiles and enables clear differentiation of the respective contributions of inorganic and organic components. Then we apply the composite approach to a variety of 2D HOPs, assessing the impact on the confinement potentials of well and barrier thickness, of the nature of the inorganic well, and of structural transitions. Using the deduced potentials, we further discuss the limitations of the effective mass approximation, scrutinizing the electronic properties of this family of composite materials. Our simulations demonstrate type-I dominant band alignment in 2D HOPs. Finally, we outline design principles on band alignment toward achieving specific optoelectronic properties. Thus, we present alternative theoretical methods to inspect the properties of 2D hybrid perovskites and expect that the composite approach will be applicable to other classes of layered materials.
Three Spool High Efficiency Small Scale Gas Turbine Concept (2017)

Decentralized electricity and heat production is a rising trend in small-scale industry. There is a tendency towards more distributed power generation. The decentralized power generation is also pushed forward by the policymakers. Reciprocating engines and gas turbines have an essential role in the global decentralized energy markets and improvements in their electrical efficiency have a substantial impact from the environmental and economic viewpoints. This paper introduces an intercooled and recuperated three stage, three-shaft gas turbine concept in 850 kW electric output range. The gas turbine is optimized for a realistic combination of the turbomachinery efficiencies, the turbine inlet temperature, the compressor specific speeds, the recuperation rate and the pressure ratio. The new gas turbine design is a natural development of the earlier two-spool gas turbine construction and it competes with the efficiencies achieved both with similar size reciprocating engines and large industrial gas turbines used in heat and power generation all over the world and manufactured in large production series. This paper presents a small-scale gas turbine process, which has a simulated electrical efficiency of 48% as well as thermal efficiency of 51% and can compete with reciprocating engines in terms of electrical efficiency at nominal and partial load conditions.
Modelling of the Heat and Mass Transfer in a Liquid Desiccant Dehumidifier with Extended Surface (2011)

This study presents a new idea of liquid desiccant dehumidifier with extended surface to improve the compactness. Extended surface is inserted between vertical cooling tubes, and the liquid desiccant flows down along the tube walls and the extended surface as well. Though the extended surface contributes to the increase in the mass transfer area, the effect tends to be limited because less conductive non-metallic materials need to be applied due to the high corrosiveness of liquid desiccant. To analyze the effects of the extended surface insertion, mathematical modelling and numerical integration are performed for the heat and mass transfer in the liquid desiccant dehumidifier. The results show that, though the liquid desiccant on the extended surface is heated due to the moisture absorption, the temperature can be maintained by periodic mixing at the contact points between the tube and the extended surface with the liquid desiccant stream from the tube side at a relatively low temperature. This implies the absorption heat from the extended surface side can be removed effectively by mixing, which leads to a substantial improvement of the dehumidification in the liquid desiccant dehumidifier with extended surface. When the interval of the extended surface, <TEX>$p_e/L$</TEX>, is less than 0.1, the dehumidification is shown to increase by more than two times compared with that without extended surface.
Self-organizing fuzzy control for dissolved oxygen concentration using fuzzy neural network1 (2016)

In order to improve the accuracy and adaptive ability of dissolved oxygen concentration control in the wastewater treatment process (WWTP), a self-organizing fuzzy control (SOFC) method is developed in this paper. The main feature of this control system is that the fuzzy controller can extract fuzz y rules automatically using a self-organizing fuzzy neural network (FNN), which can adjust the network structure during the process based on the growing-pruning-combining algorithm. Furthermore, to ensure the convergence of the system, a compensation controller is designed to dispel the FNN approximation error, and the parameter compensation is also considered while adjusting the network structure. Finally, simulation results, based on the international benchmark simulation model No.1 (BSM1), demonstrate that the proposed method can achieve better control performance and superior adaptive ability compared with PID, model predictive control and conventional fuzzy logic controller.
Design of a Single Degree-of-Freedom, Adaptable Electromechanical Gait Trainer for People With Neurological Injury (2018)

The cost of therapy is one of the most significant barriers to recovery after neurological injury. Robotic gait trainers move the legs through repetitive, natural motions imitating gait. Recent meta-analyses conclude that such training improves walking function in neurologically impaired individuals. While robotic gait trainers promise to reduce the physical burden on therapists and allow greater patient throughput, they are prohibitively costly. Our novel approach is to design a new single degree-of-freedom (DoF) robotic trainer that maintains the key advantages of the expensive trainers but with a simplified design to reduce cost. Our primary design challenge is translating the motion of a single actuator to an array of natural gait trajectories. We address this with an eight-link Jansen mechanism that matches a generalized gait trajectory. We then optimize the mechanism to match different trajectories through link length adjustment based on nine different gait patterns obtained from gait database of 113 healthy individuals. To physically validate the range in gait patterns produced by the simulation, we tested kinematic accuracy on a motorized wooden proof-of-concept of the gait trainer. The simulation and experimental results suggested that an adjustment of two links can reasonably fit a wide range of gait patterns under typical within-subject variance. We conclude that this design could provide the basis for a low-cost, patient-based electromechanical gait trainer for neurorecovery.
Interactions of Primary Amphipathic Cell Penetrating Peptides with Model Membranes: Consequences on the Mechanisms of Intracellular Delivery of Therapeutics (2005)

This review focuses on two peptides, MPG and Pep-1, which facilitate the transfer of nucleic acids and proteins, respectively, into subcellular compartments. We have investigated the interactions between these two carrier peptides and model membrane systems as well as the conformational consequences of these interactions. Studies performed with lipid monolayers at the air-water interface have enabled identification of the nature of the lipid-peptide interactions and characterization of the influence of phospholipids on the ability of these peptides to penetrate into lipidic media. Penetration and compression experiments reveal that both peptides interact strongly with phospholipids, and observations on Langmuir-Blodgett transfers indicate that they can modify the lipid organization. Conformational investigations indicate that the lipid-peptide interaction govern the conformational state of the peptides. Based on the ability of both peptides to promote ion permeabilization of both natural and artificial membranes, we propose a model illustrating the translocation process. For MPG it is based on the formation of a beta-barrel pore-like structure while for Pep-1 it is based on association of helices.
Synchrotron XRD Measurements of Thermal Barrier Coating Configurations With Rare Earth Elements for Phosphor Thermometry (2019)

Abstract The development of temperature sensing Thermal Barrier Coating (TBC) systems by phosphor thermometry has significant potential to achieve accurate non-destructive temperature measurement in the coating. The doping of coatings using rare earth elements is a viable option to enable the temperature measurement by the virtue of their luminescence. While facilitating the temperature sensing, however, the thermo-mechanical and thermo-chemical stability of the coating must be maintained under extreme operating conditions. In this work, TBC configurations including a doped layer placed at the top or the bottom of the top coat have been fabricated via Air Plasma Spray (APS) using Yttria-Stabilized Zirconia (YSZ) that contains Europium (Eu) dopant. The TBC configurations have been characterized using high energy synchrotron X-ray diffraction (XRD) at both room temperature and high temperature. The TBC samples have been subjected to a single cycle thermal load during XRD data collection. The residual strain in the top coats of the TBCs have been quantified using XRD data. Residual strain in the top coat of the regular TBC configuration has been measured to be in the range of −0.8 × 10−4 to −1.0 × 10−4 for out-of-plane strain (e11) and 0.5 × 10−4 to 2.0 × 10−4 for in-plane strain (e22). The doped layer above the top coat was found to most significantly affect the spatial strain distribution across depth in the YSZ layer by increasing the strain magnitudes closer to the bond coat. However, the difference in strain distribution due to doped layers was found to be less than 1.0 × 10−4, which is close to the experimental limit. Thus, the doped layer did not significantly alter the overall residual strain states of the coating.
A theory of redo recovery (2003)

Our goal is to understand redo recovery. We define an installation graph of operations in an execution, an ordering significantly weaker than conflict ordering from concurrency control. The installation graph explains recoverable system state in terms of which operations are considered installed. This explanation and the set of operations replayed during recovery form an invariant that is the contract between normal operation and recovery. It prescribes how to coordinate changes to system components such as the state, the log, and the cache. We also describe how widely used recovery techniques are modeled in our theory, and why they succeed in providing redo recovery.