gebhart/patrepeval huggingface dataset:
Directed Self-Assembly of Block Copolymers for High Breakdown Strength Polymer Film Capacitors (2016)

Emerging needs for fast charge/discharge yet high-power, lightweight, and flexible electronics requires the use of polymer-film-based solid-state capacitors with high energy densities. Fast charge/discharge rates of film capacitors on the order of microseconds are not achievable with slower charging conventional batteries, supercapacitors and related hybrid technologies. However, the current energy densities of polymer film capacitors fall short of rising demand, and could be significantly enhanced by increasing the breakdown strength (EBD) and dielectric permittivity (εr) of the polymer films. Co-extruded two-homopolymer component multilayered films have demonstrated much promise in this regard showing higher EBD over that of component polymers. Multilayered films can also help incorporate functional features besides energy storage, such as enhanced optical, mechanical, thermal and barrier properties. In this work, we report accomplishing multilayer, multicomponent block copolymer dielectric films (BCDF) with soft-shear driven highly oriented self-assembled lamellar diblock copolymers (BCP) as a novel application of this important class of self-assembling materials. Results of a model PS-b-PMMA system show ∼50% enhancement in EBD of self-assembled multilayer lamellar BCP films compared to unordered as-cast films, indicating that the breakdown is highly sensitive to the nanostructure of the BCP. The enhancement in EBD is attributed to the "barrier effect", where the multiple interfaces between the lamellae block components act as barriers to the dielectric breakdown through the film. The increase in EBD corresponds to more than doubling the energy storage capacity using a straightforward directed self-assembly strategy. This approach opens a new nanomaterial paradigm for designing high energy density dielectric materials.
Verifying Computations with Streaming Interactive Proofs (2011)

When computation is outsourced, the data owner would like to be assured that the desired computation has been performed correctly by the service provider. In theory, proof systems can give the necessary assurance, but prior work is not sufficiently scalable or practical. In this paper, we develop new proof protocols for verifying computations which are streaming in nature: the verifier (data owner) needs only logarithmic space and a single pass over the input, and after observing the input follows a simple protocol with a prover (service provider) that takes logarithmic communication spread over a logarithmic number of rounds. These ensure that the computation is performed correctly: that the service provider has not made any errors or missed out some data. The guarantee is very strong: even if the service provider deliberately tries to cheat, there is only vanishingly small probability of doing so undetected, while a correct computation is always accepted. We first observe that some theoretical results can be modified to work with streaming verifiers, showing that there are efficient protocols for problems in the complexity classes NP and NC. Our main results then seek to bridge the gap between theory and practice by developing usable protocols for a variety of problems of central importance in streaming and database processing. All these problems require linear space in the traditional streaming model, and therefore our protocols demonstrate that adding a prover can exponentially reduce the effort needed by the verifier. Our experimental results show that our protocols are practical and scalable.
PROSTATE TUMOR-STROMAL GENE EXPRESSION SIGNATURES IN WELL AND POORLY DIFFERENTIATED CANCERS (2008)

You have accessJournal of Urology1 Apr 2008PROSTATE TUMOR-STROMAL GENE EXPRESSION SIGNATURES IN WELL AND POORLY DIFFERENTIATED CANCERS Syed M Shaheduzzaman, Bungo Furusato, Lakshmi Ravindranath, Maryanne Vahey, David G McLeod, Isabell A Sesterhenn, Gyorgy Petrovics, and Shiv Srivastava Syed M ShaheduzzamanSyed M Shaheduzzaman More articles by this author , Bungo FurusatoBungo Furusato More articles by this author , Lakshmi RavindranathLakshmi Ravindranath More articles by this author , Maryanne VaheyMaryanne Vahey More articles by this author , David G McLeodDavid G McLeod More articles by this author , Isabell A SesterhennIsabell A Sesterhenn More articles by this author , Gyorgy PetrovicsGyorgy Petrovics More articles by this author , and Shiv SrivastavaShiv Srivastava More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(08)61337-3AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "PROSTATE TUMOR-STROMAL GENE EXPRESSION SIGNATURES IN WELL AND POORLY DIFFERENTIATED CANCERS." The Journal of Urology, 179(4S), pp. 455–456 © 2008 by American Urological AssociationFiguresReferencesRelatedDetails Volume 179Issue 4SApril 2008Page: 455-456 Advertisement Copyright & Permissions© 2008 by American Urological AssociationMetricsAuthor Information Syed M Shaheduzzaman More articles by this author Bungo Furusato More articles by this author Lakshmi Ravindranath More articles by this author Maryanne Vahey More articles by this author David G McLeod More articles by this author Isabell A Sesterhenn More articles by this author Gyorgy Petrovics More articles by this author Shiv Srivastava More articles by this author Expand All Advertisement PDF downloadLoading ...
Bombesin receptor antagonists. 5 new irreversible alkylating analogues. (1992)

New alkylating bombesin analogues were synthesized in order to increase their solubility and stability in aqueous solutions. The best compromise between these parameters and the biological properties (receptor binding and antagonistic activity) was achieved with 4-[bis(2-chloro-ethylamino)]benzoyl derivatives of the BN (7-14) octapeptide carrying a (13-14) reduced peptide bond independently of the presence of a His12 residue, either free or protected.
Development and Initial Calibration of a Portable Laser-Induced Fluorescence System Used for In Situ Measurements of Trace Plastics and Dissolved Organic Compounds in Seawater and the Gulf of Mexico (2003)

A portable UV laser-induced fluorescence system that uses a high pulsed repetition frequency (8-kHz) microchip laser at 266 nm, 13 switchable optical filters, and a gated photomultiplier tube detector has been developed and tested successfully for the detection of leached plastics (possibly bisphenol-A) and trace dissolved organic compounds in seawater. The instrument is 100 times more sensitive than commercial portable spectrofluorometers and measures a complete fluorescence spectrum in a moderate time period of 1-2 min. The system was tested in the Gulf of Mexico over varying water masses. In addition, fluorescence lifetime, bleaching, and temporal flow characteristics were studied.
The Basic Helix-Loop-Helix-PAS Protein MOP9 Is a Brain-Specific Heterodimeric Partner of Circadian and Hypoxia Factors (2000)

PAS (PER, ARNT, SIM) proteins play important roles in adaptation to low atmospheric and cellular oxygen levels, exposure to certain environmental pollutants, and diurnal oscillations in light and temperature. In an attempt to better understand how organisms sense environmental changes, we have characterized a novel member of the PAS superfamily, MOP9 (member of PAS superfamily), that maps to human chromosome 12p11.22-11.23. This protein displays significant homology to the Drosophila circadian factor CYCLE and its putative mammalian ortholog MOP3/bMAL1. Like its homologs, MOP9 forms a transcriptionally active heterodimer with the circadian CLOCK protein, the structurally related MOP4, and hypoxia-inducible factors, such as HIF1alpha. In a manner consistent with its role as a biologically relevant partner of these proteins, MOP9 is coexpressed in regions of the brain such as the thalamus, hypothalamus, and amygdala. Importantly, MOP9 is coexpressed with CLOCK in the suprachiasmatic nucleus, the site of the master circadian oscillator in mammals.
An Electrically Conducting Dendrimer (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAn Electrically Conducting DendrimerRobert G. Duan, Larry L. Miller, and Donald A TomaliaCite this: J. Am. Chem. Soc. 1995, 117, 43, 10783–10784Publication Date (Print):November 1, 1995Publication History Published online1 May 2002Published inissue 1 November 1995https://pubs.acs.org/doi/10.1021/ja00148a037https://doi.org/10.1021/ja00148a037research-articleACS PublicationsRequest reuse permissionsArticle Views396Altmetric-Citations53LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information Get e-Alerts
Direct-View Multi-Point Two-Component Interferometric Rayleigh Scattering Velocimeter (2008)

This paper describes an instantaneous velocity measurement system based on the Doppler shift of elastically scattered laser light from gas molecules (Rayleigh scattering) relative to an incident laser. The system uses a pulsed laser as the light source, direct-viewing optics to collect the scattered light, an interferometer to analyze spectrally the scattered light mixed with the incident laser light, and a CCD camera to capture the resulting interferogram. The system is capable of simultaneous, spatially (approximately 0.2 mm(exp 3)) and temporally (approximately 40 ns) resolved, multiple point measurements of two orthogonal components of flow velocity in the presence of background scattered light, acoustic noise and vibrations, and flow particulates. Measurements in a large-scale axi-symmetric Mach 1.6 H2-air combustion-heated jet running at a flow sensible enthalpy specific to Mach 5.5 hypersonic flight are performed to demonstrate the technique. The measurements are compared with CFD calculations using a finite-volume discretization of the Favre-averaged Navier-Stokes equations (VULCAN code).
A Novel CMKLR1 Small Molecule Antagonist Suppresses CNS Autoimmune Inflammatory Disease (2014)

Therapies that target leukocyte trafficking pathways can reduce disease activity and improve clinical outcomes in multiple sclerosis (MS). Experimental autoimmune encephalomyelitis (EAE) is a widely studied animal model that shares many clinical and histological features with MS. Chemokine-like receptor-1 (CMKLR1) is a chemoattractant receptor that is expressed by key effector cells in EAE and MS, including macrophages, subsets of dendritic cells, natural killer cells and microglia. We previously showed that CMKLR1-deficient (CMKLR1 KO) mice develop less severe clinical and histological EAE than wild-type mice. In this study, we sought to identify CMKLR1 inhibitors that would pharmaceutically recapitulate the CMKLR1 KO phenotype in EAE. We identified 2-(α-naphthoyl) ethyltrimethylammonium iodide (α-NETA) as a CMKLR1 small molecule antagonist that inhibits chemerin-stimulated β-arrestin2 association with CMKLR1, as well as chemerin-triggered CMKLR1+ cell migration. α-NETA significantly delayed the onset of EAE induced in C57BL/6 mice by both active immunization with myelin oligodendrocyte glycoprotein peptide 35-55 and by adoptive transfer of encephalitogenic T cells. In addition, α-NETA treatment significantly reduced mononuclear cell infiltrates within the CNS. This study provides additional proof-of-concept data that targeting CMKLR1:chemerin interactions may be beneficial in preventing or treating MS.
Large splitting and long reach passive optical networks with mode coupling receivers (2010)

A novel architecture for optical line terminal using mode coupling receiver is proposed for large-splitting/long-reach passive optical networks. 1:256-split and 40km-reach passive optical networks are demonstrated for the first time without using an optical amplifier or regenerator.
Transformation of the multimode terahertz quantum cascade laser beam into a Gaussian, using a hollow dielectric waveguide (2007)

We demonstrate that a short hollow dielectric tube can act as a dielectric waveguide and transform the multimode, highly diverging terahertz quantum cascade laser beam into the lowest order dielectric waveguide hybrid mode, EH(11), which then couples efficiently to the free-space Gaussian mode, TEM(00). This simple approach should enable terahertz quantum cascade lasers to be employed in applications where a spatially coherent beam is required.
Storage Coding for Wear Leveling in Flash Memories (2009)

Flash memory is a non-volatile computer memory comprised of blocks of cells, wherein each cell is implemented as either NAND or NOR floating gate. NAND flash is currently the most widely used type of flash memory. In a NAND flash memory, every block of cells consists of numerous pages; rewriting even a single page requires the whole block to be erased and reprogrammed. Block erasures determine both the longevity and the efficiency of a flash memory. Therefore, when data in a NAND flash memory are reorganized, minimizing the total number of block erasures required to achieve the desired data movement is an important goal. This leads to the flash data movement problem studied in this paper. We show that coding can significantly reduce the number of block erasures required for data movement, and present several optimal or nearly optimal data-movement algorithms based upon ideas from coding theory and combinatorics. In particular, we show that the sorting-based (non-coding) schemes require at least O(nlogn) erasures to move data among n blocks, whereas coding-based schemes require only O(n) erasures. Furthermore, coding-based schemes use only one auxiliary block, which is the best possible, and achieve a good balance between the number of erasures in each of the n+1 blocks.
Steganalysis of LSB encoding in color images (2002)

Analyzes the security of least significant bit (LSB) embedding for hiding messages in high-color-depth digital images. We introduce a powerful steganalytic technique that enables us to reliably detect the presence of a pseudorandom binary message randomly spread in a color image. We estimate the probability of both false detections and missing a secret message. The method is based on statistical analysis of the image colors in the RGB cube. It is shown that, even for secret message capacities of 0.1-0.3 bits per pixel, it is possible to achieve a high degree of detection reliability.
Guidance of Unmanned Aerial Vehicles (2011)

Basics of Guidance Guidance Process Missile Guidance Guidance of Cruise Missiles and UAVs Representation of Motion Line-of-Sight Longitudinal and Lateral Motions Control of Lateral Motion Parallel Navigation Proportional Navigation: Planar Engagement Proportional Navigation: Three-Dimensional Engagement Augmented Proportional Navigation Proportional Navigation as a Control Problem Augmented Proportional Navigation as a Control Problem When Is the PN law Optimal? Control of Longitudinal and Lateral Motions Guidance Correction Controls Lyapunov Approach to Control Law Design Bellman-Lyapunov Approach: Optimal Guidance Parameters Modified Linear Planar Model of Engagement General Planar Case Three-Dimensional Engagement Model Generalized Guidance Laws Modifies Generalized Guidance Laws Examples Analysis of Proportional Navigation Guided Systems in Time Domain Inertialess PN Guidance System Method of Adjoints Analysis of Proportional Navigation Guided Systems in the Frequency Domain Adjoint Method: Generalized Model Frequency Domain Analysis Steady-State Miss Analysis Weave Maneuver Analysis Example Frequency Analysis and Miss Step Response Bounded Input-Bounded Output Stability Frequency Response of the Generalized Guidance Model Design of Guidance Laws Implementing Parallel Navigation: Frequency-Domain Approach Neoclassical Missile Guidance Pseudoclassical Missile Guidance Example Systems Guidance Law Performance Analysis Under Stochastic Inputs Brief Discussion of Stochastic Processes Random Target Maneuvers Analysis of Influence of Noises on Miss Distance Effect of Random Target Maneuvers on Miss Distance Computational Aspects Examples Filtering Guidance of UAVs Basic Guidance Laws and Vision-Based Navigation Generalized Guidance Laws for UAVs Guidance of a Swarm of UAVs Obstacle Avoidance Algorithms Testing Guidance Laws Performance Forces Acting on Unmanned Aerial Vehicles Reference Systems and Transformations Unmanned Aerial Vehicles Dynamics Autopilot and Actuator Model Seeker Model Filtering and Estimation Kappa Guidance Lambert Guidance Simulation Models of Unmanned Aerial Vehicles Integrated Design Integrated Guidance and Control Model Synthesis of Control Laws Integration and Decomposition Guidance Laws for Boost-Phase Interceptors Launched from UAVs Kill Vehicles for Boost-Phase Defense Development of the Missile Model and Selection of Guidance Law Parameters Endgame Requirements and the Comparative Analysis of Efficiency of Guidance Laws Advanced Guidance Laws Applied to Boost Stage Interceptor's Performance With Axial Control Comparative Analysis with Lambert Guidance Appendices
Property specific information flow analysis for hardware security verification (2018)

Hardware information flow analysis detects security vulnerabilities resulting from unintended design flaws, timing channels, and hardware Trojans. These information flow models are typically generated in a general way, which includes a significant amount of redundancy that is irrelevant to the specified security properties. In this work, we propose a property specific approach for information flow security. We create information flow models tailored to the properties to be verified by performing a property specific search to identify security critical paths. This helps find suspicious signals that require closer inspection and quickly eliminates portions of the design that are free of security violations. Our property specific trimming technique reduces the complexity of the security model; this accelerates security verification and restricts potential security violations to a smaller region which helps quickly pinpoint hardware security vulnerabilities.
Measurement of Multi-segment Foot Joint Angles During Gait Using a Wearable System (2012)

Usually the measurement of multi-segment foot and ankle complex kinematics is done with stationary motion capture devices which are limited to use in a gait laboratory. This study aimed to propose and validate a wearable system to measure the foot and ankle complex joint angles during gait in daily conditions, and then to investigate its suitability for clinical evaluations. The foot and ankle complex consisted of four segments (shank, hindfoot, forefoot, and toes), with an inertial measurement unit (3D gyroscopes and 3D accelerometers) attached to each segment. The angles between the four segments were calculated in the sagittal, coronal, and transverse planes using a new algorithm combining strap-down integration and detection of low-acceleration instants. To validate the joint angles measured by the wearable system, three subjects walked on a treadmill for five minutes at three different speeds. A camera-based stationary system that used a cluster of markers on each segment was used as a reference. To test the suitability of the system for clinical evaluation, the joint angle ranges were compared between a group of 10 healthy subjects and a group of 12 patients with ankle osteoarthritis, during two 50-m walking trials where the wearable system was attached to each subject. On average, over all joints and walking speeds, the RMS differences and correlation coefficients between the angular curves obtained using the wearable system and the stationary system were 1 deg and 0.93, respectively. Moreover, this system was able to detect significant alteration of foot and ankle function between the group of patients with ankle osteoarthritis and the group of healthy subjects. In conclusion, this wearable system was accurate and suitable for clinical evaluation when used to measure the multi-segment foot and ankle complex kinematics during long-distance walks in daily life conditions.
Characterization of protective immunity induced against<i>Schistosoma mansoni</i>via DNA priming with the large subunit of calpain (Sm-p80) in the presence of genetic adjuvants (2005)

Despite advances in control via snail eradication and large-scale chemotherapy using praziquental, schistosomiasis continues to spread to new geographic areas particularly in sub-Saharan Africa. Presently, there is no vaccine for controlling this disease. We have concentrated on a functionally important schistosome antigen Sm-p80 as a possible vaccine candidate for schistosomiasis. Here we report the proliferation of spleen cells in response to the recombinant Sm-p80 protein and cytokine (IFN-gamma and IL-4) production by the splenocytes. These spleen cells were obtained from groups of mice that were vaccinated with a DNA vaccine formulation containing Sm-p80 and one of the Th-1 (IL-2 or IL-12) or Th-2 (GM-CSF, IL-4) enhancer cytokines. The splenocytes from the groups of mice vaccinated with Sm-p80 DNA in the presence of Th-2 enhancer cytokines showed moderate but detectable proliferation. The splenocytes obtained from mice vaccinated with Sm-p80 DNA with Th-1 enhancer cytokines IL-2 and IL-12 provided the highest proliferation. The IFN-gamma production by splenocytes was found to follow the similar pattern [(Sm-p80) < (Sm-p80 + IL-4) < (Sm-p80 + GMCSF) < (Sm-p80 + IL-12) < (Sm-p80 + IL-2)], as has been observed for the proliferation and protection data. However, the elevated IL-4 production was inversely correlated to Sm-p80-induced splenocyte proliferation or the protection. These results show again that protective immune response induced by Sm-p80 is of Th-1 type.
Coherent radar detection in log-normal clutter (1986)

The paper deals with the problem of radar detection of a target echo embedded in log-normal clutter and white Gaussian noise. Relevant features of this article, with respect to previous papers on the same subject, refer to the coherent model assumed for the clutter and the processing chain. In more detail, the in-phase and quadrature components of clutter have been modelled to give a log-normal amplitude distribution and a near uniform distribution of the phase. Any shape of the correlation among consecutive clutter samples is also allowed in the model. At the same time, the processing chain is also coherent, i.e. it operates on the two components of the signals. Two architectures have been considered for the processor. The first, used in current practice, is formed of a linear transversal filter (for the clutter attenuation and the target echo enhancement) cascaded with a quadratic envelope detector and a comparison with a suitable threshold. The second processor considered differs from the previous one in the filter for clutter cancellation. A nonlinear homomorphic filter has been conceived to obtain a better suppression of clutter. The detection performance of the two processing chains have been evaluated, by means of computer simulation, in a number of operational cases of intrest. The paper gives a first contribution to the problem of finding better models of disturbance and of deriving more efficient processing chains.