gebhart/patrepeval huggingface dataset:
The ALIS He ion source and its application to high resolution microscopy (2008)

Highly stressed aerospace structures, such as the wing attachment points and load carry-through bulkheads of fighter aircraft, often grow fatigue cracks from micro-scale discontinuities. These cracks spend much of their lives close to these discontinuities in the small crack regime. The accurate prediction of fatigue crack growth in this small crack regime leads to setting realistic inspection thresholds for the aircraft and assisting in accurate risk-based assessment of the lives of such cracks. Fractography can greatly aid the assessment of the growth of small cracks. It has traditionally been carried out using optical and Scanning Electron Microscopes to gather the necessary small crack growth rate data, however, limitations on the resolution and the surface sensitivity of these instruments restricts the gathering of crack growth rate data at small crack lengths. As an extension to the current capabilities, the newly introduced Helium Ion Microscope offers improved nano-scale resolution and topographical sensitivity. As a result, the Helium Ion Microscope offers the potential for both quantitative and qualitative analysis of small fatigue crack growth about nucleating discontinuities at resolutions previously unobtainable. This paper presents an overview of the technology and gives three different fractographic examples of its possible applications to failure analysis. These examples include extension of small crack fractography, extension of near initiation fractographic feature analysis, and extension of nano-scale feature analysis. To demonstrate these capabilities, fatigue fractures produced by experimental loading spectra that were applied to the aluminium alloy AA7050-T7451 have been investigated.
Copper-Catalyzed trans-Hydroboration of Terminal Aryl Alkynes: Stereodivergent Synthesis of Alkenylboron Compounds (2016)

A Cu-catalyzed highly Z-stereoselective hydroboration of alkynes with 1,8-naphthalenediaminatoborane (HB(dan)) is developed. DPEphos (bis[(2-diphenylphosphino)phenyl]ether)-ligated Cu catalysts produced alkenylboron compounds from terminal alkynes with excellent Z-stereoselectivity. In contrast, using a SIPr-CuCl complex as the precatalyst exclusively produced E-hydroboration products at mild conditions. Both catalytic procedures form alkenylboron products stereocomplementary to each other, constituting stereodivergent hydroboration of alkynes through Cu catalysis. Deuterium labeling and isomerization studies support the Z-selective hydroboration via trans-addition of the boron reagent to terminal alkynes as opposed to precedent noble-metal-catalyzed trans-hydroborations.
Screening of the antimalarial activity of plants of the Cucurbitaceae family (1991)

Crude ethanolic extracts (CEEs) from two species of Cucurbitaceae, Cucurbita maxima and Momordica charantia (commonly called "abóbora moranga" and "melão de São Caetano", respectively) were assayed for antimalarial activity by the 4-d suppressive test. The CEE of dry C. maxima seeds showed strong antimalarial activity following oral administration (250 and 500 mg/kg), reducing by 50% the levels of parasitemia in Plasmodium berghei-infected mice. Treatment of normal animals with 500 mg/kg of the extract three days before intravenous injection of P. berghei caused a significant 30% reduction in parasitemic levels. No effect was observed when the animals were treated with the CEE only on the day of inoculation. Oral administration of the CEE of dry M. charantia leaves administered orally was ineffective up to 500 mg/kg in lowering the parasitemic levels of malarious mice.
Radiation Dose and Labeling of Hippuran (2015)

Renal morphology and renal function were studied with iodine-123-hippurate in 98 patients with various renal diseases. Sequential scintigraphy with iodine-123-hippurate demonstrates much better renal blood flow, morphology and function than iodine-131-hippurate. A method of labeling hippurate in a short time (2 h) with high efficiency (95--100%) is described. Radiation exposure to various organs was calculated and significant differences in radiation exposure to the thyroid are demonstrated.
Glycoprotein 340 in Normal Human Ocular Surface Tissues and Tear Film (2006)

The tear film is a complex mixture of secreted fluid, ions, proteins, glycoproteins, and lipids that lubricates and protects the ocular surface. Recently, several antimicrobial peptides have been described in the tear fluid. In this study, we describe the presence of the large secreted glycoprotein gp340 in the tear film. Western blot analysis showed that gp340 is abundant in secreted tears and in the lacrimal glands. Lesser amounts of gp340 were detected in the cornea and conjunctiva. Consistent with Western blot data, reverse transcription-PCR and real-time quantitative PCR showed that gp340 transcripts were abundant in lacrimal gland tissue and were also present in the cornea and conjunctiva. Immunohistochemistry localized gp340 to the acinar cells of the lacrimal gland and the deeper layers of the conjunctival epithelium. gp340 was not detected in conjunctival goblet cells. In the cornea, gp340 was present only in a peripheral band of basal epithelial cells, suggesting that gp340 may play a role in the cycle of corneal epithelial renewal. To determine if tear film gp340 may function as a bacterial agglutinin as it does in saliva, tears were incubated with streptococcal cells and the formation of bacterial aggregates was monitored. Addition of tears to late-exponential-phase Streptococcus mutans cells resulted in time- and dose-dependent aggregation of the bacteria. Furthermore, Western blot analysis confirmed the presence of cell-associated gp340 in isolated bacterial aggregates. The ocular pathogen Staphylococcus aureus, but not Pseudomonas aeruginosa, also aggregated when incubated with tears. These results suggest that gp340 is a normal component of the tear film and that the glycoprotein may function as a bacterial agglutinin.
Resultados académicos y desarrollo cognitivo en un programa de inmersión dirigido a escolares de nivel socio-cultural bajo (1989)

ResumenEste artículo hace un repaso de las principales características de los programas de inmersión así como de las bases psicopedagógicas en las que se fundamentan, encontrándose argumentos a favor de la aplicación de este tipo de programas a escolares con bajo nivel socio-cultural. Esta investigación ha llevado a cabo la evaluación y seguimiento al final del ciclo inicial de una muestra de alumnos que empezaron a los 4 años un programa de inmersión realizado en una escuela situada en el barrio del Carmel de Barcelona y ha comparado los resultados obtenidos con los de otra escuela, situada en el mismo barrio, que realiza la enseñanza en la lengua familiar de los alumnos (castellano).
Performance analysis of a high-speed dynamically reconfigurable LAN (2002)

We present the design of a dynamically reconfigurable switch that will be used to build a highspeed multi-link ring local area network. Using FPGAs technology, switch reconfigurability can be exploited to implement different interconnection topologies and support different application requirements. We present two approaches to analyze the multi-link ring network performance. In the first approach, we develop an analytical model that uses the M/M/n and M/D/n queuing systems to study the virtual channels access delay. In this approach, the virtual channel occupancy probabilities are found using an infinite state Markov model. In the second approach, we introduce an analytical model based on a finite state Markov model developed for analysing networks with virtual channels flow control. Simulation, using the OPNET tool, indicates that the second approach is more accurate in analyzing the behavior of the packet transfer time. Furthermore our performance analysis shows that the use of wormhole routing and virtual channel flow control improves the system throughput and decreases the packet transfer time.
Regulation of Mammalian Circadian Behavior by Non-rod, Non-cone, Ocular Photoreceptors (1999)

Circadian rhythms of mammals are entrained by light to follow the daily solar cycle (photoentrainment). To determine whether retinal rods and cones are required for this response, the effects of light on the regulation of circadian wheel-running behavior were examined in mice lacking these photoreceptors. Mice without cones (cl) or without both rods and cones (rdta/cl) showed unattenuated phase-shifting responses to light. Removal of the eyes abolishes this behavior. Thus, neither rods nor cones are required for photoentrainment, and the murine eye contains additional photoreceptors that regulate the circadian clock.
Loss of Work Productivity due to Illness and Medical Treatment (1999)

We examined the effects on work productivity of treatment with antihistamines in a retrospective study using linked health claims data and daily work output records for a sample of nearly 6000 claims processors at a large insurance company, between 1993 and 1995. We explained the variation in work output depending on the subjects' demographic characteristics, their jobs, and whether they were treated with "sedating" versus "nonsedating" antihistamines for nasal allergies. Differences of up to 13% in productivity were found after the subjects took sedating or nonsedating antihistamines. The observed effect suggests substantial indirect economic costs, which up to now have been largely overlooked because work productivity has proved difficult to measure objectively.
Intratracheal instillation of keratinocyte growth factor decreases hyperoxia-induced mortality in rats. (1995)

Alveolar type II cell proliferation occurs after many forms of lung injury and is thought to play a critical role in alveolar epithelial repair. Keratinocyte growth factor/fibroblast growth factor 7 (KGF) has been shown to promote alveolar type II cell growth in primary culture and alveolar epithelial hyperplasia in vivo. In this study, we used immunohistochemical analysis to determine the intrapulmonary distribution and cellular localization of recombinant human KGF (rhKGF) instilled into the trachea of rats. 6 h after administration, immunoreactive KGF was observed within the lung parenchyma and along alveolar epithelial cell membranes. By 18-24 h, KGF was detected intracellularly in alveolar epithelial cells and intraalveolar macrophages. Immunoreactive KGF was not demonstrable 48 h after delivery or in lung sections from PBS-treated animals. Intratracheal instillation of 5 mg/kg rhKGF stimulated a marked, time-dependent increase in the alveolar type II cell specific labeling index to a maximum level of 33 +/- 3% 48 h after rhKGF administration compared with 1.3 +/- 0.3% after PBS instillation. In addition, this increase in type II cell proliferation in vivo was documented by flow cytometric analysis of isolated type II cells which revealed a nearly fivefold increase in the proportion of cells traversing through the S and G2/M phases of the cell cycle. To test the hypothesis that KGFs effects on type II cells in vivo might affect the response to lung injury, rats were treated with rhKGF and exposed to hyperoxia. Animals that received 1 or 5 mg/kg rhKGF exhibited dramatically reduced mortality (P < 0.001, for both doses). Survival for animals treated with 0.1 mg/kg rhKGF was not significantly different from either untreated rats or animals treated with heat-denatured rhKGF. The lungs of rhKGF-treated animals that survived hyperoxia exposure had minimal hemorrhage and no exudate within the intraalveolar space. These experiments established that intratracheal administration of rhKGF stimulated alveolar type II cell proliferation in vivo and reduced hyperoxia-induced lung injury in rats. Directed delivery of KGF to the lungs may provide a therapeutic strategy to preserve or restore the alveolar epithelium during exposure to hyperoxia or other injurious agents.
Consecutive reaction monitoring in a four-sector mass spectrometer: MS4 and one step beyond (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTConsecutive reaction monitoring in a four-sector mass spectrometer: MS4 and one step beyondKenneth B. Tomer, Christian R. Guenat, and Leesa J. DeterdingCite this: Anal. Chem. 1988, 60, 20, 2232–2236Publication Date (Print):October 15, 1988Publication History Published online1 May 2002Published inissue 15 October 1988https://pubs.acs.org/doi/10.1021/ac00171a014https://doi.org/10.1021/ac00171a014research-articleACS PublicationsRequest reuse permissionsArticle Views103Altmetric-Citations34LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Tensile Property Evaluation of Polycrystalline Alumina Filaments and Their Composites (1983)

The tensile failure stresses of polycrystalline alumina filaments (DuPont Fiber FP) were experimentally measured and statistically evaluated for several different gage lengths 1.27, 2.54, 5.0, 7.6, 12.7, and 25.4 cm. Static and dynamic tensile elastic moduli results also are reported, and a method for determining the true fiber gage length is described.
Random Access Preamble Design and Detection for 3GPP Narrowband IoT Systems (2016)

Narrowband internet of things (NB-IoT) is an emerging cellular technology that will provide improved coverage for massive number of low-throughput low-cost devices with low device power consumption in delay-tolerant applications. A new single tone signal with frequency hopping has been designed for NB-IoT physical random access channel (NPRACH). In this letter we describe this new NPRACH design and explain in detail the design rationale. We further propose possible receiver algorithms for NPRACH detection and time-of-arrival estimation. Simulation results on NPRACH performance including detection rate, false alarm rate, and time-of-arrival estimation accuracy are presented to shed light on the overall potential of NB-IoT systems.
Allogeneic hematopoietic stem cell transplantation from family members other than HLA-identical siblings over the last decade (1991-2000) (2003)

The reported outcome of hematopoietic stem cell transplantation (HSCT) from HLA-mismatched family members has been inconsistent. The object of this study was to evaluate the true impact of HLA-mismatch by using recent data from a homogenous population, excluding HSCT procedures that used graft manipulations, and by considering genotypic matching. Clinical data of 2947 patients who underwent allogeneic HSCT for leukemia or myelodysplastic syndrome were extracted from the database of the Japan Society for Hematopoietic Cell Transplantation. The main outcome measures were survival and the incidence of graft-versus-host disease (GVHD). The presence of serologic HLA-mismatch, higher age, and high-risk disease were identified as independent risk factors for both shorter survival and the development of grade III to IV acute GVHD. The impact of HLA-mismatch on survival was more relevant in standard-risk patients. These findings persisted when we used genotypic HLA matching. Survival after one-locus-mismatched HSCT was equivalent to that after HLA-matched unrelated HSCT. We concluded that when a one-locus-mismatched family donor is available for high-risk patients, immediate HSCT using this donor is warranted. In standard-risk patients, however, survival after one-locus-mismatched HSCT is significantly shorter than that after HLA-matched HSCT, and the indications for HSCT should be considered carefully.
A multicenter, retrospective, observational study of the clinical outcomes and risk factors for relapse of ulcerative colitis at 1 year after leukocytapheresis (2017)

The majority of patients (>60%) with UC treated with LCAP achieved clinical remission within 1 year and remained relapse-free. A higher Lichtiger CAI and leukocyte count following LCAP were risk factors for relapse. Re-induction therapy with LCAP was effective for relapse of UC.
Inactivation of Organellar Glutamyl- and Seryl-tRNA Synthetases Leads to Developmental Arrest of Chloroplasts and Mitochondria in Higher Plants (2005)

Aminoacyl-tRNA synthetases (ARSs) are key enzymes involved in protein translation, and both cytosolic and organellar forms are present in the genomes of eukaryotes. In this study, we investigated cellular effects of depletion of organellar forms of ARS using virus-induced gene silencing (VIGS) in Nicotiana benthamiana. VIGS of NbERS and NbSRS, which encode organellar GluRS and SerRS, respectively, resulted in a severe leaf-yellowing phenotype. The NbERS and NbSRS genes were ubiquitously expressed in plant tissues, and induced in response to light. Green fluorescent protein (GFP) fusion proteins of the full-length glutamyl-tRNA synthetase (ERS) and seryl-tRNA synthetase (SRS) of Arabidopsis and GFP fusions to the N-terminal extension of these proteins were all dualtargeted to chloroplasts and mitochondria. At the cell level, depletion of NbERS and NbSRS resulted in dramatically reduced numbers of chloroplasts with reduced sizes and chlorophyll content. The numbers and/or physiology of mitochondria were also severely affected. The abnormal chloroplasts lacked most of the thylakoid membranes and appeared to be degenerating, whereas some of them showed doublet morphology, indicating defective chloroplast division. Pulse-field gel electrophoresis analyses demonstrated that chloroplast DNA in subgenomic sizes is the predominant form in the abnormal chloroplasts. Interestingly, despite severe abnormalities in chloroplasts and mitochondria, expression of many nuclear genes encoding chloroplastor mitochondria-targeted proteins, and chlorophyll biosynthesis genes remained unchanged in the ERS and SRS VIGS lines. This is the first report to analyze the effect of ARS disruption on organelle development in plants.
Polymers, Fractals, and Ceramic Materials (1989)

Concepts borrowed from polymer science have been applied to tailor the properties of inorganic materials, especially those derived from amorphous precursors. Fractal geometry can be used to characterize macromolecular precursors and to relate their structures to kinetic growth processes. Within the silica system, for example, it is possible to manipulate the conditions of solution polymerization to yield a variety of macromolecules from branched chains to smooth colloidal particles.
Global Diffusion via Cascading Invitations (2015)

Many of the world's most popular websites catalyze their growth through invitations from existing members. New members can then in turn issue invitations, and so on, creating cascades of member signups that can spread on a global scale. Although these diffusive invitation processes are critical to the popularity and growth of many websites, they have rarely been studied, and their properties remain elusive. For instance, it is not known how viral these cascades structures are, how cascades grow over time, or how diffusive growth affects the resulting distribution of member characteristics present on the site. In this paper, we study the diffusion of LinkedIn, an online professional network comprising over 332 million members, a large fraction of whom joined the site as part of a signup cascade. First we analyze the structural patterns of these signup cascades, and find them to be qualitatively different from previously studied information diffusion cascades. We also examine how signup cascades grow over time, and observe that diffusion via invitations on LinkedIn occurs over much longer timescales than are typically associated with other types of online diffusion. Finally, we connect the cascade structures with rich individual-level attribute data to investigate the interplay between the two. Using novel techniques to study the role of homophily in diffusion, we find striking differences between the local, edge-wise homophily and the global, cascade-level homophily we observe in our data, suggesting that signup cascades form surprisingly coherent groups of members.
Deep Learning for RF Fingerprinting: A Massive Experimental Study (2020)

RF fingerprinting is a key security mechanism that allows device identification by learning unchanging, hardware-based characteristics of the transmitter. In this article, we demonstrate how machine learning techniques impact RF fingerprinting by analyzing a dataset of 400 GB of in-phase (I) and quadrature (Q) signal data transmitted by 10,000 radios. Our deep convolutional neural network architectures take raw and processed IQ samples as input to identify devices under a variety of practical conditions, including changing channels, noise levels, training data sizes, and computational overheads, among others. The contributions of the article are as follows: (i) This is the first work, to the best of our knowledge, reporting on RF fingerprinting and scalability issues on very large device populations, in the range of 50-10,000 devices. (ii) We investigate how to mitigate the effect of the wireless channel through a feature engineering step that we refer to as partial equalization. (iii) We provide a comprehensive performance evaluation of both a custom-designed and a modified ResNet architecture, with insights on which one may be preferred under specific environmental conditions.
Research on the Establishment, Operation and Management of "Farm Helper" APP (2023)

The poverty problem in China has an important connection with the precision sales of agricultural products. We are committed to providing farmers with all-round help, taking "farmers' income increase, agricultural growth, and rural stability" as our mission, and comprehensively helping farmers develop and become rich. Therefore, our team has developed a central APP called "Agricultural Helper", which provides a safe, reliable and convenient platform for farmers to sell agricultural products. Our platform eliminates many redundant steps and directly contacts with enterprises such as fruit processing plants and canning plants. The platform also provides a personal to personal marketing model to further simplify the transportation of agricultural products and ensure the quality of agricultural products, such marketing mode can reduce the purchase cost of enterprise users and individual users. This paper introduces the main functions, products and services of the "agricultural helper" APP, analyzes its marketing strategies, and analyzes its risk types and countermeasures.
45 Degree Polymer Micromirror Integration for Board-Level Three-Dimensional Optical Interconnects (2009)

We introduce here a simple method of integrating 45 degrees total internal reflection micro-mirrors with polymer optical waveguides by an improved tilted beam photolithography on printed circuit boards to provide surface normal light coupling between waveguides and optoelectronic devices for optical interconnects. De-ionized water is used to couple ultraviolet beam through the waveguide core polymer layer at 45 degrees angle during the photo exposure process. This technique is compatible with PCB manufacturing facility and suitable to large panel board-level manufacturing. The mirror slope is controlled accurately (within +/- 1 degrees) with high repeatability. The insertion loss of an uncoated micro-mirror is measured to be 1.6 dB.