gebhart/patrepeval huggingface dataset:
Integrin‐specific hydrogels functionalized with VEGF for vascularization and bone regeneration of critical‐size bone defects (2015)

Vascularization of bone defects is considered a crucial component to the successful regeneration of large bone defects. Although vascular endothelial growth factor (VEGF) has been delivered to critical-size bone defect models to augment blood vessel infiltration into the defect area, its potential to increase bone repair remains ambiguous. In this study, we investigated whether integrin-specific biomaterials modulate the effects of VEGF on bone regeneration. We engineered protease-degradable, VEGF-loaded poly(ethylene glycol) (PEG) hydrogels functionalized with either a triple-helical, α2 β1 integrin-specific peptide GGYGGGP(GPP)5 GFOGER(GPP)5 GPC (GFOGER) or an αv β3 integrin-targeting peptide GRGDSPC (RGD). Covalent incorporation of VEGF into the PEG hydrogel allowed for protease degradation-dependent release of the protein while maintaining VEGF bioactivity. When applied to critical-size segmental defects in the murine radius, GFOGER-functionalized VEGF-free hydrogels exhibited significantly increased vascular volume and density and resulted in a larger number of thicker blood vessels compared to RGD-functionalized VEGF-free hydrogels. VEGF-loaded RGD hydrogels increased vascularization compared to VEGF-free RGD hydrogels, but the levels of vascularization for these VEGF-containing RGD hydrogels were similar to those of VEGF-free GFOGER hydrogels. VEGF transiently increased bone regeneration in RGD hydrogels but had no effect at later time points. In GFOGER hydrogels, VEGF did not show an effect on bone regeneration. However, VEGF-free GFOGER hydrogels resulted in increased bone regeneration compared to VEGF-free RGD hydrogels. These findings demonstrate the importance of integrin-specificity in engineering constructs for vascularization and associated bone regeneration.
Simulation analysis of a communication link with statistically multiplexed bursty noise sources (1993)

Variable bit rate (VBR) coding techniques have received great research interest as very promising tools for transmitting bursty multimedia traffic with low bandwidth requirements over a communication link. Statistically multiplexing the multimedia bursty traffic is a very efficient method of maximizing the utilization of the link capacity. The application of computer simulation techniques in analyzing a rate-based access control scheme for multimedia traffic such as voice traffic is discussed. The control scheme regulates the packetized bursty traffic at the user network interface of the link. Using a suitable congestion measure, namely, the multiplexer buffer length, the scheme dynamically controls the arrival rate by switching the coder to a different compression ratio (i.e., changing the coding rate). VBR coding methods can be adaptively adjusted to transmit at a lower rate with very little degradation in the voice quality. Reported results prove that the scheme greatly improves the link performance, in terms of reducing the probability of call blocking and enhancing the statistical multiplexing gain.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Isolation and Characterization of Proteins from Chia Seeds (Salvia hispanica L.) (2012)

Chia ( Salvia hispanica L.) is a plant that produces seeds rich in some nutraceutical compounds with high protein content, but little is known about them; for this reason the aim of this study was to characterize the seed storage proteins. Protein fractions were extracted from chia seed flour. The main protein fraction corresponded to globulins (52%). Sedimentation coefficient studies showed that the globulin fraction contains mostly 11S and 7S proteins. The molecular sizes of all the reduced fractions were about 15-50 kDa. Electrophoretic experiments under native conditions exhibited four bands of globulins in the range of 104-628 kDa. The denaturation temperatures of crude albumins, globulins, prolamins, and glutelins were 103, 105, 85.6, and 91 °C, respectively; albumins and globulins had relatively good thermal stability. Selected globulin peptides by mass spectrometry showed homology to sesame proteins. A good balance of essential amino acids was found in the seed flour and globulins, especially of methionine+cysteine.
Multi-hop broadcast message dissemination in vehicular ad hoc networks: A security perspective review (2017)

Vehicular ad hoc networks have been identified as a key technology for enabling safety and infotainment applications in the context of smart and connected vehicles. In this sense, diverse approaches of multi-hop broadcast protocols have been proposed to collect and disseminate context information through the network. However, before vehicular ad hoc networks applications fulfill their expected potential to connect smart vehicles, several issues must be addressed. Among these issues, those related to security are of particular importance. In this article, the main security issues of broadcast message dissemination in vehicular ad hoc networks are discussed. Moreover, a review of the most relevant threats and proposed solutions to secure broadcast message dissemination in vehicular ad hoc networks is presented and discussed. As mentioned, security is an important topic which has not been fully addressed in vehicular ad hoc networks; therefore, the aim of this article is to introduce security issues and proposed solutions related to three main security concerns associated with the message dissemination process in vehicular ad hoc networks: network access, data consistency, and broadcast protocols.
Ensure Hierarchal Identity Based Data Security in Cloud Environment (2019)

Cloud computing has emerged as a new promising field in the internet. It can be thought as a new architecture for the next generation of IT enterprises. It allows the user to access virtualized resources over the internet which can be dynamically scaled. Here, the owner's data is stored at a distributed data centre, which are responsible for its security constraints such as access control and data transmission to user. As the owner does not have physical access on their own data, the data centres are not trustworthy, this resulted in the cloud data security demand. Today, many cloud service providers (CSPs) are using the asymmetric and public key cryptography (PKG) for authenticating and data security purposes using the digital identity of the user. To this end, this article focuses on cloud data storage and its delivery to authorized user. For this purpose, a hierarchal identity-based cryptography method is used for data security and checking the data integrity, in order to make sure that there is no alteration or modification done by a malicious attacker or CSP for its own benefit.
Synthesis and characterization of barium titanate-based solid solution nanocubes (2016)

Ba(Zrx,Ti1−x)O3 nanocubes (BZTx NCs) were synthesized by hydrothermal reaction with titanium and zirconium aqueous compounds and surfactants. The nanocubes were assembled on the substrates by dropping-drying method. The microstructures of the nanocube were evaluated by field emission scanning electron microscopy (FE-SEM) and transmission electron microscopy (TEM). The ordered assemblies of the NCs were yielded on the substrate when Zr contents were below 0.2. BZT0.2 NCs had narrow size distribution about 20 nm observed by FE-SEM and TEM. On the other hand, BZT0.5 and BaZrO3 NCs were attached each other and they formed large cube above 100 nm. Perovskite phase was confirmed in all BZTx NCs by X-ray diffraction. Lattice constant of BZTx NCs increased linearly with increasing Zr contents. The composition of BZT0.2 NCs were calculated by X-ray photoelectron spectroscopy. These results suggest that the ratio of Ba:Zr:Ti is nearly equal to the nominal ratio. Crystallographic phase of BaTiO3 and BZT0.2 NCs was characterized by Raman spectroscopy under various measurement temperatures.
Compact 60-GHz lens antenna with self-alignment feature for small cell backhaul (2017)

In this paper we present a highly compact and low-cost antenna solution based on a dielectric lens and a waveguide horn array feed for operation in the 57–64 GHz frequency band. The antenna is targeted for applications in point-to-point backhaul systems for Small Cell mobile access networks and features a beamforming capability providing self-alignment for ease of installation and improved link stability.
Pneumatic stabilization of iatrogenic flail chest with CPAP: a case report. (2010)

Iatrogenic flail chest following resection of part of the chest wall in postoperative patients is a challenging scenario for the anesthetist. It can lead to long term morbidity and even death, if adequate management is not instituted. We describe the management of postoperative flail chest, following resection of upper two-third of the sternum along with costal cartilages for a malignant thymoma invading the sternum in an adult male with the use of continuous epidural analgesia and continuous positive airway pressure (CPAP), which provided pneumatic stabilization and an excellent recovery.
A Direct, Biomass‐Based Synthesis of Benzoic Acid: Formic Acid‐Mediated Deoxygenation of the Glucose‐Derived Materials Quinic Acid and Shikimic Acid (2010)

Shikimic Gimmick: An alternative biomass-based route to benzoic acid from the renewable starting materials quinic acid and shikimic acid is described. Benzoic acid is obtained selectively using a highly efficient, one-step formic acid-mediated deoxygenation method.
Triple modular redundancy used in field programmable neural networks (2017)

This paper presents the concepts of FPNA and FPNN, used for the approximation of artificial neural networks in FPGAs and discusses the usage of TMR technique in order to reach a fault tolerance. The diagrams of the FPGA implementation are presented. The results of experiments determining the FPGA resources utilization with different usage of the TMR technique are provided.
P‐50: Integrated Gate Drive Circuit Employing IGZO TFTs for AMOLED Compensative Pixel Driving (2015)

In order to compensate the threshold voltage variation while obtaining the sufficient data charging time, the AMOLED compensative pixel circuit needs to be driven by multi‐pulse signals which have continuous high/low level pulses. By using traditional gate driver on array (GOA) with half duty‐cycle delay of clock signals, the area of shift register is doubled, increasing the bezel width and power consumptions. In this paper, novel compact integrated gate driver circuit architectures for AMOLED pixel compensation purpose are presented. Outputs with programmable pulse width and number are achieved in these gate driving circuits without consuming extra large areas. Inner feedback technique is adopted in GOA circuit for leakage current cutting of depletion mode IGZO TFTs. The simulation result shows that these circuits work successfully with maximum ±3V threshold voltage shift. These GOA circuits can be used for internal or external V th compensation techniques of AMOLED panel.
Liquid crystalline thermosets from triaromatic ester group containing diepoxides and aromatic diamines (1998)

Three novel triaromatic diepoxides, 1,4-phenylene bis(4-(2,3-epoxypropoxy)benzoate) (1), methyl-1,4-phenylene bis(4-(2,3-epoxypropoxy)benzoate) (2), and chloro-1,4-phenylene bis(4-(2,3-epoxypropoxy)benzoate) (3), were synthesized and their mesogenic properties studied. 1 and 2 were reacted with 4,4′-diaminobiphenyl (4), 4-aminophenyl 4-aminobenzoate (5), and 4,4′-diaminodiphenylmethane (6) to investigate the formation of anisotropic networks. The influence of the curing conditions and of the structure of monomers and amines on the formation of liquid crystalline thermoset (LCT) networks has been studied. All combinations give nematic networks. The temperature range in which nematic melts and LCT are formed is determined by complete melting of the mixture and by its clearing point, which is in good agreement with the value calculated from the clearing points of the monomers. Orientation of initially liquid crystalline mixtures is better than the orientation of mixtures which form the mesophase starting from an isotropic melt.
Design of dual action antibiotics as an approach to search for new promising drugs (2014)

The review is devoted to the latest achievements in the design of dual action antibiotics ? heterodimeric (chimeric) structures based on antibacterial agents of different classes (fluoroquinolones, anthracyclines, oxazolidines, macrolides and so on). Covalent binding can make the pharmacokinetic characteristics of these molecules more predictable and improve the penetration of each component into the cell. Consequently, not only does the drug efficacy increase owing to inhibition of two targets but also the resistance to one or both antibiotics can be overcome. The theoretical grounds of elaboration, design principles and methods for the synthesis of dual action antibiotics are considered. The structures are classified according to the type of covalent spacer (cleavable or not) connecting the moieties of two agents. Dual action antibiotics with a spacer that can be cleaved in a living cell are considered as dual action prodrugs. Data on the biological action of heterodimeric compounds are presented and structure?activity relationships are analyzed. The bibliography includes 225 references.
Temporal video segmentation using global motion estimation and discrete curve evolution (2005)

The identification of syntactic or semantic temporal segments is an important process of video-content analysis. The paper proposes a temporal video segmentation method based on global motion in order to analyze meaningful temporal substructures of camera shots. To ensure that the detected segment optimally contributes to the shot global characteristic, the proposed method exploits a state-of-the-art discrete curve evolution. This technique leads to a subdivision of the global motion trajectory, where each segment of the subdivision has a constant relevant global motion. Experimental results based on standard test sequences acknowledge the method functionality, especially for shots characterized by pronounced camera motion.
Calibrating a Cartesian robot with eye-on-hand configuration independent of eye-to-hand relationship (2003)

A novel approach is described to geometric calibration of Cartesian robots. This is one-third of an overall approach to real-time 3-D robotics eye, eye-to-hand, and hand calibration, which uses a common setup and calibration object, and is especially suited to machine vision community. The robot makes a series of automatically planned movements with a camera rigidly mounted at the gripper. At the end of each move, it takes a total of 90 ms to grab an image, extract image feature coordinates, and perform camera extrinsic calibration. After the robot finishes all the movements, it takes only a few milliseconds to do the calibration. Only one single rotary joint is moving for each movement while the robot motion can still be planned such that the calibration object remains within the field of view. This allows the calibration parameters to be fully decoupled, and converts a multidimensional problem into a series of one-dimensional problems. Eye-to-hand transformation is not needed at all during the computation.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Plasma adrenomedullin is associated with short-term mortality and vasopressor requirement in patients admitted with sepsis (2014)

In patients admitted with sepsis, severe sepsis or septic shock plasma ADM is strongly associated with severity of disease, vasopressor requirement and 28-day mortality.
소주와 위스키 소비구조 분석 (2003)

우리나라 사람들의 소주와 위스키 소비는 꾸준히 증가하고 있으나 선호패턴은 외환위기를 전후로 상이한 형태를 보이고 있다. 먼저 공적분검정을 통해 모형이 안정적인 것으로 나타남에 따라 모형을 추정하여 소주의 경우 전기와 후기에 경기상승과 더불어 소비가 증가하나, 후기에는 전기에 비해 상당히 낮은 소비증가를 보이는 데 비해 위스키는 전기에는 경기상승에도 불구하고 소비가 오히려 감소하나, 후기에는 대단히 높은 소비증가가 이루어짐을 밝힌다. 또한 오차수정모형을 이용하여 주류소비의 조정이 전기에 비해 후기에 더디게 이루어지고, 위스키 소비조정이 특히 느리게 이루어진다는 점과 경기변동이 소주보다 위스키 소비에 훨씬 큰 영향을 더 오랫동안 미친다는 것도 보인다.
A new method and device of aligning patient setup lasers in radiation therapy (2016)

The aim of this study is to develop a new method to align the patient setup lasers in a radiation therapy treatment room and examine its validity and efficiency. The new laser alignment method is realized by a device composed of both a metallic base plate and a few acrylic transparent plates. Except one, every plate has either a crosshair line (CHL) or a single vertical line that is used for alignment. Two holders for radiochromic film insertion are prepared in the device to find a radiation isocenter. The right laser positions can be found optically by matching the shadows of all the CHLs in the gantry head and the device. The reproducibility, accuracy, and efficiency of laser alignment and the dependency on the position error of the light source were evaluated by comparing the means and the standard deviations of the measured laser positions. After the optical alignment of the lasers, the radiation isocenter was found by the gantry and collimator star shots, and then the lasers were translated parallel to the isocenter. In the laser position reproducibility test, the mean and standard deviation on the wall of treatment room were 32.3 ± 0.93 mm for the new method whereas they were 33.4 ± 1.49 mm for the conventional method. The mean alignment accuracy was 1.4 mm for the new method, and 2.1 mm for the conventional method on the walls. In the test of the dependency on the light source position error, the mean laser position was shifted just by a similar amount of the shift of the light source in the new method, but it was greatly magnified in the conventional method. In this study, a new laser alignment method was devised and evaluated successfully. The new method provided more accurate, more reproducible, and faster alignment of the lasers than the conventional method.
Retrieving the most probable solution in a temporal interval algebra network (2007)

Abstract:- In this paper, we propose a probability-based approach to retrieve the most probable solution in a temporal Interval Algebra (IA) network. In our approach, all probable solutions are abstracted as a Markov Chain. Based on this Markov Chain, we utilize Chapman-Kolmogorov functional equation to compute the most probable solution. Furthermore, in order to achieve easy and friendly operations for IA network’s researchers, we attempt to adopt constraint logic programming to implement software which is able to support temporal an IA network. The implementation of the software is based on finite domain non-binary CSPs. In addition, we briefly provide an application of retrieving the most probable solution to show the functions of software. Through experiments, we conclude that the implementation can satisfy the desired goal.
Derivation, simulation and validation of a cohesive particle flow CFD model (2007)

Abstract A comprehensive physical model describing the agglomeration behavior present during fluidization of fine powders is still missing in literature. A model of balance of forces acting on a single solid particle is introduced, aiming at predicting and locally estimating the size of the agglomerates created in the bed. Computational fluid dynamics (CFD) have been used to investigate the hydrodynamics of a gas‐solid fluidized bed operated with particles belonging to group A of Geldart classification. The key issue is that, in the gas and particle flow field, both hydrodynamic and interparticle forces are of importance. The model is incorporated into simulations based on an Eulerian approach and using the kinetic theory of granular flow. In the simulations, the closure models describing the hydrodynamics of the solids phase are directly affected by the behavior of the agglomerates. No empirical data or parameters were used to close the model. The simulations are compared with experiments of an independent research group, through the time‐averaged solids volume fraction in a fluidized bed operated at different gas velocities. The agreement obtained between the simulation results and data from the literature is very good. Also, it is shown that, under flow conditions treated in this work, agglomerates of size of several single particle diameters are present in the fluidized bed. © 2007 American Institute of Chemical Engineers AIChE J, 2008
Multi-functional perovskites – an investigation of compositional and processing influence on microstructure, dielectric and ferroelectric properties (2019)

Ba(Ni0.5Nb0.5)O2.75 (BNNO) doped KNbO3 (KN) and (K0.5Na0.5)NbO3 (KNN), abbreviated as KBNNO and KNBNNO, respectively, have been recently reported to co-exhibit narrow band gaps (visible range) and strong piezoelectric/pyroelectric effects simultaneously within the same material. This had never been achieved in a single ceramic material. Such a breakthrough may allure the development of fundamentally novel multi-source energy harvesters based on only one piece of material as well as advanced optoelectronic devices with multiple functions. It has been found that the window of getting the unique combination of these properties is very narrow. Even a slight shifting away from the stoichiometry of the compositions may induce a significant loss of the properties. The reasons are expected to be in the compositions and microstructure of these materials. However, detailed information – e.g. the correlation of the compositions, processing conditions, microstructure and properties – remains to be investigated for such novel materials. In this paper, the inter-influence of different doping amounts of BNNO, calcination and sintering temperatures, phase structures and defects (potassium loss and oxygen vacancy) on the dielectric and ferroelectric properties are studied. The paper reveals the principles and provides guidance to achieving good ferroelectric properties in these emerging perovskite structured materials.
Correlation of Ultrastructural Alterations in Cavernous Tissue with the Clinical Diagnosis Vasculogenic Impotence (1996)

Cavernous tissues of 27 impotent and 4 potent men were evaluated in order to determine the ultrastructural changes in patients with vasculogenic impotence. Tissue samples were obtained during penile prosthesis insertions and surgical repairs of penile fractures in impotent and potent patients, respectively. For the clinical evaluation (pharmacologic color Doppler ultrasound, dynamic pharmacocavernosometry and nocturnal penile tumescence monitoring) patients were divided into three groups: slight/moderate arterial dysfunction (n = 5), severe arterial dysfunction (n = 9) and purely cavernous erectile dysfunction (n = 9). No significant ultrastructural alteration was noticed in the group with moderate arterial dysfunction; decrease and deterioration of smooth muscle cells was the prominent finding in the severe arterial and venogenic dysfunction groups. Preliminary examination of cavernous tissue may be a part of routine evaluations in the approach to the management of erectile dysfunction.
Acute stress reaction and completed suicide (2010)

Acute stress reaction is a risk factor for completed suicide.