gebhart/patrepeval huggingface dataset:
A review of close-range and screening technologies for mitigating fugitive methane emissions in upstream oil and gas (2019)

Abstract Fugitive methane emissions from the oil and gas industry are targeted using leak detection and repair (LDAR) programs. Until recently, only a limited number of measurement standards have been permitted by most regulators, with emphasis on close-range methods (e.g. Method-21, optical gas imaging). Although close-range methods are essential for source identification, they can be labor-intensive. To improve LDAR efficiency, there has been a policy shift in Canada and the United States towards incorporating alternative technologies. However, the suitability of these technologies for LDAR remains unclear. In this paper, we systematically review and compare six technology classes for use in LDAR: handheld instruments, fixed sensors, mobile ground labs (MGLs), unmanned aerial vehicles (UAVs), aircraft, and satellites. These technologies encompass broad spatial and temporal scales of measurement. Minimum detection limits for technology classes range from <1 g h −1 for Method 21 instruments to 7.1 × 10 6 g h −1 for the GOSAT satellite, and uncertainties are poorly constrained. To leverage the diverse capabilities of these technologies, we introduce a hybrid screening-confirmation approach to LDAR called a comprehensive monitoring program. Here, a screening technology is used to rapidly tag high-emitting sites to direct close-range source identification. Currently, fixed sensors, MGLs, UAVs, and aircraft could be used as screening technologies, but their performances must be evaluated under a range of environmental and operational conditions to better constrain detection effectiveness. Methane-sensing satellites are improving rapidly and may soon be ready for facility-scale screening. We conclude with a speculative discussion of the future of LDAR, touching on integration, analytics, incentivization, and regulatory pathways.
Guatemala: El gran dilema electoral: mano dura sin corazón o sensibilidad social sin escrúpulos (2011)

A new species of Cryptinae, Endasys pristiphorae Sheng, sp.n. reared from cocoons of the tenthredinid sawflies Pristiphora erichsonii (Hartig), P. xibei Wei Xia and P. (Stauronematus) compresicornis (Hartig) in Ningxia, Shandong and Shan'xi, China, is described and illustrated. A key to species of Endasys known from China is provided.
The antimalarial action on Plasmodium falciparum of qinghaosu and artesunate in combination with agents which modulate oxidant stress (1987)

The antimalarial activity of qinghaosu (artemisinine) against Plasmodium falciparum in culture was enhanced by increased oxygen tension. Artesunate, a qinghaosu derivative, showed synergistic effects with miconazole, and with doxorubicin, both of which have been suggested to exert their chemotherapeutic effect through increasing the oxidant stress. In contrast, catalase, dithiothreitol and alpha-tocopherol reduced the effectiveness of qinghaosu in vitro. These results suggest that the action of qinghaosu and artesunate might involve increase in oxidant stress on the infected red cells.
Identification and Characterization of Four Azole-Resistant <i>erg3</i> Mutants of <i>Candida albicans</i> (2010)

ABSTRACT Sterol analysis identified four Candida albicans erg3 mutants in which ergosta 7,22-dienol, indicative of perturbations in sterol Δ 5,6 -desaturase (Erg3p) activity, comprised >5% of the total sterol fraction. The erg3 mutants (CA12, CA488, CA490, and CA1008) were all resistant to fluconazole, voriconazole, itraconazole, ketoconazole, and clotrimazole under standard CLSI assay conditions (MIC values, ≥256, 16, 16, 8, and 1 μg ml −1 , respectively). Importantly, CA12 and CA1008 retained an azole-resistant phenotype even when assayed in the presence of FK506, a multidrug efflux inhibitor. Conversely, CA488, CA490, and three comparator isolates (CA6, CA14, and CA177, in which ergosterol comprised >80% of the total sterol fraction and ergosta 7,22-dienol was undetectable) all displayed azole-sensitive phenotypes under efflux-inhibited assay conditions. Owing to their ergosterol content, CA6, CA14, and CA177 were highly sensitive to amphotericin B (MIC values, <0.25 μg ml −1 ); CA1008, in which ergosterol comprised <2% of the total sterol fraction, was less sensitive (MIC, 1 μg ml −1 ). CA1008 harbored multiple amino acid substitutions in Erg3p but only a single conserved polymorphism (E266D) in sterol 14α-demethylase (Erg11p). CA12 harbored one substitution (W332R) in Erg3p and no residue changes in Erg11p. CA488 and CA490 were found to harbor multiple residue changes in both Erg3p and Erg11p. The results suggest that missense mutations in ERG3 might arise in C. albicans more frequently than currently supposed and that the clinical significance of erg3 mutants, including those in which additional mechanisms also contribute to resistance, should not be discounted.
The Constancy of Leopold's Land Ethic (1988)

Abstract: Aldo Leopold's approach to environmental management changed drastically between the early 1920s, when he advocated predator eradication, and 1944, when he drafted “Thinking Like a Mountain.” How are we to understand these changes? It is shown that, early in his career, Leopold developed the basic elements of a conservation ethic, borrowing key elements from the Russian organicist P. D. Ouspensky and from A. T. Hadley, an American pragmatist who was president of Yale University when Leopold was a student there. Hadley's pragmatism counseled that we act on the wisdom embodied in the intuitive perceptions of our forefathers. While Leopold changed the presentation of his conservation ethic over the years, he never gave up these key ideas, traces of which remain in the final version of “The Land Ethic.” The changes in Leopold's management strategies were not due to a change in metaphysical or moral views, but to his evolving experience as a forester and game manager. Leopold learned that “violent” strategies, such as monocultural planting of trees, pervasive agricultural management of fragile ecosystems and, above all predator eradication, led to unforeseen and unwelcome results. Leopold recognized that we may never have adequate information to manipulate natural systems for maximal human utility without diminishing their vitality. He therefore lost faith in “economic biology” as a guide to environmental management. Leopold's changing views on management resulted from his experience as an environmental manager, not from a conversion from utilitarian anthropocentrism to biocentric nonanthropocentrism. While Leopold was drawn to Ouspensky's organicism, and he hoped Americans would through a profound change in their perceptions of nature adopt such a view eventually, he believed throughout his career that longsighted anthropocentrism provides an adequate basis for conservation practices.
Synthesis and characterization of the isoelectronic d10 species bis[bis(methyldiphenylsilyl)amido]cuprate(1-) and -zinc (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis and characterization of the isoelectronic d10 species bis[bis(methyldiphenylsilyl)amido]cuprate(1-) and -zincPhilip P. Power, Karin Ruhlandt-Senge, and Steven C. ShonerCite this: Inorg. Chem. 1991, 30, 26, 5013–5015Publication Date (Print):December 1, 1991Publication History Published online1 May 2002Published inissue 1 December 1991https://pubs.acs.org/doi/10.1021/ic00026a029https://doi.org/10.1021/ic00026a029research-articleACS PublicationsRequest reuse permissionsArticle Views255Altmetric-Citations50LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Design of low-cost modular RF front end for RF fingerprinting of Bluetooth signals (2017)

For RF fingerprinting of wireless devices, data acquisition has a critical role. Because of this, highly sophisticated devices are used for data capturing or acquisition. In this paper, design of a RF receiver front end with modular components is presented. This design contains filtering and down conversion processing of Bluetooth signals for cellular phones. Moreover, AWR VSS and MATLAB have been used for simulating the down converter circuit. With this simulation, effects of components that used in the design on recorded signal have been observed. In this work in progress paper, only high SNR conditions are considered.
Can one predict protein stability? An attempt to do so for residue 133 of T4 lysozyme using a combination of free energy derivatives, PROFEC, and free energy perturbation methods (1998)

Free energy derivatives, pictorial representation of free energy changes (PROFEC) and free energy perturbation methods were employed to suggest the modifications that may improve the stability of a mutant T4 lysozyme with a S-2-amino-3-cyclopentylpropanoic acid residue (Cpe) at position 133. The free energy derivatives and PROFEC methods were used to locate promising sites where modifications may be introduced. The effects of several candidate modifications on the enzyme's stability were analyzed by the free energy perturbation method. We found that this scheme is able to effectively suggest modifications that may increase the enzyme's stability. The modifications investigated are the introduction of a methyl, a tert-butyl or a trifluoromethyl group at the Cϵ2 position and a cyclopropyl group between the Cδ2 and Cϵ2 position on the cyclopentyl ring. The stereochemistry of the introduced groups (in the α or β configurations) was studied. Our calculations predict that the introduction of a methyl group in the α configuration or a cyclopropyl group in the β configuration will increase the stability of the enzyme; the introduction of the two groups in the other configurations and the other modifications will decrease the stability of the enzyme. The results indicate that packing interactions can strongly influence the stability of the enzyme. Proteins 32:438–458, 1998. © 1998 Wiley-Liss, Inc.
Using speakeasy for ad hoc peer-to-peer collaboration (2002)

Peer-to-peer systems appear promising in terms of their ability to support ad hoc, spontaneous collaboration. However, current peer-to-peer systems suffer from several deficiencies that diminish their ability to support this domain, such as inflexibility in terms of discovery protocols, network usage, and data transports. We have developed the Speakeasy framework, which addresses these issues, and supports these types of applications. We show how Speakeasy addresses the shortcomings of current peer-to-peer systems, and describe a demonstration application, called Casca, that supports ad hoc peer-to-peer collaboration by taking advantages of the mechanisms provided by Speakeasy.
High-Order Multiblock Copolymers via Iterative Cu(0)-Mediated Radical Polymerizations (SET-LRP): Toward Biological Precision (2011)

We report a new approach for the facile synthesis of high-order multiblock copolymers comprising very short blocks. The approach entails sequential addition of different monomers via an iterative single electron transfer-living radical polymerization technique, allowing nearly perfect control of the copolymer microstructure. It is possible to synthesize high-order multiblock copolymers with unprecedented control, i.e., A-B-C-D-E-etc., without any need for purification between iterative 24 h block formation steps. To illustrate this concept, we report the synthesis of model P(MA-b-MA...) homopolymer and P(MA-b-nBuA-b-EA-b-2EHA-b-EA-b-nBuA) copolymer in extremely high yield. Finally, the halide end-group can be modified via "click chemistry", including thiol-bromide click chemistry, sodium methanethiosulfonate nucleophilic substitution, and atom transfer radical nitroxide coupling reaction, to yield functional, structurally complex macromolecules.
<title>Polysilanes for microlithography</title> (1991)

We have recently reported the formation of scum-free micron images in a bilayer composed of a thin (1500 angstrom) imaging layer of poly(cyclohexylmethylsilane) coated over a thick planarizing layer of a hardbaked diazoquinone-novalac type photoresist using deep UV exposure. Although excellent resolution was achieved (< 0.5 micrometers ) in this process, the exposure doses required (125-150 mJ/cm2) were higher than desirable for commercial DUV imaging tools. We have addressed this problem using two approaches: (i) the synthesis of new polysilanes which are intrinsically more sensitive to photodegradation in the solid state and (ii) the incorporation of additives which enhance the photosensitivity. Regarding the former, a number of aryl substituted polysilane homopolymers which are significantly more photolabile than the standard poly (methylphenylsilane), as assayed by the rate of spectral photobleaching upon exposure to DUV radiation, have been prepared and tested. In addition, a number of small molecule additives which quantitatively quench the polymer fluorescence in the solid state have been identified. Some of the additives which efficiently quench the polymer fluorescence in the solid state also accelerate the rate of photodegradation. The combination of the new polysilane materials with sensitizing additives has allowed submicron DUV imaging at exposure doses as low as 20 mJ/cm2 or less in a bilayer configuration employing O2-RIE for image transfer of the wet-developed images.
Inhibition by all-<i>trans</i>-retinoic acid of tumor necrosis factor and nitric oxide production by peritoneal macrophages (1994)

Besides their growth-inhibiting and differentiation-inducing properties, retinoids have been shown to exert immunomodulatory and anti-inflammatory functions by mechanisms that are not well understood. Tumor necrosis factor-alpha (TNF), a cytokine produced by mononuclear phagocytes, has been shown to be an important mediator of endotoxin-induced septic shock, cachexia, bone resorption, and inflammation. Nitric oxide may also have a role in septic shock, hypotension, and vasodilatation. In this study, we examined the effects of retinoids on the production of TNF and nitric oxide by murine peritoneal macrophages. Of the various retinoids studied, all-trans-retinoic acid (RA) was most potent; it almost completely inhibited the production of TNF by macrophages activated with endotoxin and interferon-gamma. The inhibitory effect was dependent on the dose and duration of RA exposure to macrophages. RA also blocked phorbol ester-induced TNF production in a macrophage cell line (RAW 264.7). Besides TNF, the retinoid suppressed the production of nitric oxide from activated peritoneal macrophages. The importance of these results in relation to controlling various harmful effects of cytokines released by activated macrophages is discussed.
Nonprotein amino acid furanomycin, unlike isoleucine in chemical structure, is charged to isoleucine tRNA by isoleucyl-tRNA synthetase and incorporated into protein. (1990)

Nonprotein amino acid furanomycin was found to bind with Escherichia coli isoleucyl-tRNA synthetase (IleRS) almost as tightly as the substrate L-isoleucine. The conformation of furanomycin bound to the enzyme was determined by NMR analyses including the transferred nuclear Overhauser effect method. The conformation of IleRS-bound furanomycin was similar to that of L-isoleucine, although the chemical structure of furanomycin is unlike that of L-isoleucine. By E. coli IleRS, E. coli tRNAIle was charged with furanomycin as efficiently as with L-isoleucine. Furthermore, furanomycyl-tRNAIle was bound to polypeptide chain elongation factor Tu as tightly as isoleucyl-tRNAIle. Furanomycin was found to be incorporated into beta-lactamase precursor by in vitro protein biosynthesis. A newly designed amino acid will probably be incorporated into proteins, provided that the new amino acid takes a similar conformation as a protein-constituting amino acid in the active site of an aminoacyl-tRNA synthetase.
Epigenetics in Kidney Transplantation (2015)

Epigenetic modifications are changes to the genome that occur without any alteration in DNA sequence. These changes include cytosine methylation of DNA at cytosine-phosphate diester-guanine dinucleotides, histone modifications, microRNA interactions, and chromatin remodeling complexes. Epigenetic modifications may exert their effect independently or complementary to genetic variants and have the potential to modify gene expression. These modifications are dynamic, potentially heritable, and can be induced by environmental stimuli or drugs. There is emerging evidence that epigenetics play an important role in health and disease. However, the impact of epigenetic modifications on the outcomes of kidney transplantation is currently poorly understood and deserves further exploration. Kidney transplantation is the best treatment option for end-stage renal disease, but allograft loss remains a significant challenge that leads to increased morbidity and return to dialysis. Epigenetic modifications may influence the activation, proliferation, and differentiation of the immune cells, and therefore may have a critical role in the host immune response to the allograft and its outcome. The epigenome of the donor may also impact kidney graft survival, especially those epigenetic modifications associated with early transplant stressors (e.g., cold ischemia time) and donor aging. In the present review, we discuss evidence supporting the role of epigenetic modifications in ischemia-reperfusion injury, host immune response to the graft, and graft response to injury as potential new tools for the diagnosis and prediction of graft function, and new therapeutic targets for improving outcomes of kidney transplantation.
Background field removal using spherical mean value filtering and Tikhonov regularization (2013)

Compared with SHARP, RESHARP removes background field artifact more effectively, leading to more accurate susceptibility measurements in iron-rich deep gray matter.
A switched capacitor subranging A/D conversion technique (2003)

A capacitor ratio independent subranging analog-to-digital (A/D) conversion technique is proposed. Conversion is performed by using high resolution coarse and fine reference voltage levels. The digital-to-analog (D/A) converter in the structure generates coarse and fine reference voltage levels for subranging A/D conversion. These reference voltages are stored in a capacitor array which is refreshed periodically. High-resolution A/D conversion is achieved by comparing the input voltage with these voltage levels. The proposed subranging A/D conversion technique also uses a parallel structure for analog subtraction. Improved resolution is obtained without increasing the number of conversion steps. Simulation of the algorithm in PSPICE shows results that are consistent with theoretical analysis.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Motor current signature analysis method for diagnosing motor operated devices (2023)

A motor current noise signature analysis method for remotely monitoring the operating characteristics of an electric motor-operated device such as a motor-operated valve. Frequency domain signal analysis techniques are applied to a conditioned motor current signal to distinctly identify various operating parameters of the motor driven device from the motor current signature. The signature may be recorded and compared with subsequent signatures to detect operating abnormalities and degradation of the device. This diagnostic method does not require special equipment to be installed on the motor-operated device, and the current sensing may be performed at remote control locations, e.g., where the motor-operated devices are used in inaccessible or hostile environments. 6 figs.
MP-LOCKs: replacing H/W synchronization primitives with message passing (1999)

Shared memory programs guarantee the correctness of concurrent accesses to shared data using interprocessor synchronization operations. The most common synchronization operators are locks, which are traditionally implemented via a mix of shared memory accesses and hardware synchronization primitives like test-and-set. In this paper, we argue that synchronization operations implemented using fast message passing and kernel-embedded lock managers are an attractive alternative to dedicated synchronization hardware. We propose three message passing lock (MP-LOCK) algorithms (centralized, distributed, and reactive) and provide implementation guidelines. MP-LOCKs reduce the design complexity and runtime occupancy of DSM controllers and can exploit software's inherent flexibility to adapt to differing applications lock access patterns. We compared the performance of MP-LOCKs with two common shared memory lock algorithms: test-and-test-and-set and MCS locks and found that MP-LOCKs scale better. For machines with 16 to 32 nodes, applications using MP-LOCKs ran up to 186% faster than the same applications with shared memory locks. For small systems (up to 8 nodes), three applications with MP-LOCKs slow down by no more than 18%, while the other two slowed by no more than 180% due to higher software overhead. We conclude that locks based on message passing should be considered as a replacement for hardware locks in future scalable multiprocessors that support efficient message passing mechanisms.
Fingerprint verification using SIFT features (2008)

Fingerprints are being extensively used for person identification in a number of commercial, civil, and forensic applications. Most of the current fingerprint verification systems utilize features that are based on minutiae points and ridge patterns. While minutiae based fingerprint verification systems have shown fairly high accuracies, further improvements in their performance are needed for acceptable performance, especially in applications involving very large scale databases. In an effort to extend the existing technology for fingerprint verification, we propose a new representation and matching scheme for fingerprint using Scale Invariant Feature Transformation (SIFT). We extract characteristic SIFT feature points in scale space and perform matching based on the texture information around the feature points using the SIFT operator. A systematic strategy of applying SIFT to fingerprint images is proposed. Using a public domain fingerprint database (FVC 2002), we demonstrate that the proposed approach complements the minutiae based fingerprint representation. Further, the combination of SIFT and conventional minutiae based system achieves significantly better performance than either of the individual schemes.