gebhart/patrepeval huggingface dataset:
Effects of hydrogen peroxide-induced oxidative damage on outflow facility and washout in pig eyes. (1991)

Previous studies show that hydrogen peroxide (H2O2) is present in the aqueous humor of many species and is capable of affecting outflow facility in animal model experiments. To study the hypothesis that oxidative damage to the outflow pathway may play a role in the pathogenesis of primary open-angle glaucoma, 3 mM H2O2 with 20 mM 3-aminotriazole and 1 mM carmustine (BCNU) in Dulbecco's phosphate-buffered saline (DPBS) was perfused into enucleated pig eyes at constant pressure. Baseline and experimental perfusions were done at two different pressures (7.5 and 30 mm Hg) to study the effect of pressure on the response to oxidative damage. Outflow facility in the baseline experiments (with DPBS only) was observed to increase nonlinearly with time during the perfusions, but could be linearized if plotted as a function of the volume perfused. Thus, a term "volumetric washout" (W) was introduced and defined as the fractional rate of change of outflow facility with respect to the volume perfused. This quantity was found to be independent of pressure in the baseline studies. Perfusion of H2O2 and inhibitors increased W at 7.5 mm Hg but decreased W at 30 mm Hg. These results indicate that oxidative damage increases outflow facility at normal pressure but decreases it at elevated pressure, suggesting that elevated pressure may increase the susceptibility of the outflow pathway to this form of insult.
MRPB: Memory request prioritization for massively parallel processors (2014)

Massively parallel, throughput-oriented systems such as graphics processing units (GPUs) offer high performance for a broad range of programs. They are, however, complex to program, especially because of their intricate memory hierarchies with multiple address spaces. In response, modern GPUs have widely adopted caches, hoping to providing smoother reductions in memory access traffic and latency. Unfortunately, GPU caches often have mixed or unpredictable performance impact due to cache contention that results from the high thread counts in GPUs. We propose the memory request prioritization buffer (MRPB) to ease GPU programming and improve GPU performance. This hardware structure improves caching efficiency of massively parallel workloads by applying two prioritization methods-request reordering and cache bypassing-to memory requests before they access a cache. MRPB then releases requests into the cache in a more cache-friendly order. The result is drastically reduced cache contention and improved use of the limited per-thread cache capacity. For a simulated 16KB L1 cache, MRPB improves the average performance of the entire PolyBench and Rodinia suites by 2.65× and 1.27× respectively, outperforming a state-of-the-art GPU cache management technique.
Multi-Attribute Double Auctions in Financial Trading (2006)

Double-sided auctions are popular market mechanisms for determining the price of standardized commodities. However, many trades - like for example OTC trades of financial derivatives and bonds - require multi-attribute handling. To this end, the class of continuous-time multi-attribute double auction mechanisms is introduced. The paper outlines requirements, characterizes the class of auction mechanisms, points out design options, and discusses the implementation in the meet2trade/sup 2/ system.
Design and Evaluation of Intervehicle Dissemination Protocol for Propagation of Preceding Traffic Information (2007)

In this paper, we propose an intervehicle information dissemination protocol called received message-dependent protocol (RMDP) that propagates the preceding traffic information to the following vehicles and discuss its performance. The proposed protocol autonomously changes the dissemination interval, depending on the number of reception messages and detected reception errors, in order to avoid message collision among vehicles. We have constructed a realistic simulation environment of intervehicle communication by combining a traffic-flow simulator and an ad hoc network simulator. Our simulation results show that, by using RMDP, a lot of vehicles can acquire their preceding traffic information within short periods at both the conditions with light and heavy traffic. In addition, we have also shown that selection policy of disseminated data affects preceding-traffic-information acquisition time. Each vehicle holds other vehicles' traces for some period. Depending on the number of preserved other vehicles' traces and their preserved periods, the propagation ratio of the preceding traffic information varies. Some simulation results are explained.
Electronic Structure of Anilinopyridinate-Supported Ru<sub>2</sub><sup>5+</sup> Paddlewheel Compounds (2017)

The electronic structures of the diruthenium compounds Ru<sub>2</sub>(ap)<sub>4</sub>Cl (1, ap = 2-anilinopyridinate) and Ru<sub>2</sub>(ap)<sub>4</sub>OTf (2) were investigated with UV-vis, resonance Raman, and magnetic circular dichroism (MCD) spectroscopies; SQUID magnetometry; and density functional theory (DFT) calculations. Both compounds have quartet spin ground states with large axial zero-field splitting of ∼60 cm<sup>-1</sup> that is characteristic of Ru<sub>2</sub><sup>5+</sup> compounds having a (π*, δ*)<sup>3</sup> electron configuration and a Ru-Ru bond order of ∼2.5. Two major visible absorption features are observed at ∼770 and 430 nm in the electronic spectra, the assignments of which have previously been ambiguous. Both bands have significant charge-transfer character with some contributions from d → d transitions. MCD spectra were measured to enable the identification of d → d transitions that are not easily observable by UV-vis spectroscopy. In this way, we are able to identify bands due to δ → δ* and δ → π* transitions at ∼16 100 and 11 200-12 300 cm<sup>-1</sup>, respectively, the latter band being sensitive to the π-donating character of the axial ligand. The Ru-Ru stretches are coupled with pyridine rocking motions and give rise to observed resonance Raman peaks at ∼350 and 420 cm<sup>-1</sup>, respectively.
Role-Based Access Control for Grid Database Services Using the Community Authorization Service (2006)

In this paper, we propose a role-based access control (RBAC) method for grid database services in open grid services architecture-data access and integration (OGSA-DAI). OGSA-DAI is an efficient grid-enabled middleware implementation of interfaces and services to access and control data sources and sinks. However, in OGSA-DAI, access control causes substantial administration overhead for resource providers in virtual organizations (VOs) because each of them has to manage a role-map file containing authorization information for individual grid users. To solve this problem, we used the community authorization service (CAS) provided by the globus toolkit to support the RBAC within the OGSA-DAI framework. The CAS grants the membership on VO roles to users. The resource providers then need to maintain only the mapping information from VO roles to local database roles in the role-map files, so that the number of entries in the role-map file is reduced dramatically. Furthermore, the resource providers control the granting of access privileges to the local roles. Thus, our access control method provides increased manageability for a large number of users and reduces day-to-day administration tasks of the resource providers, while they maintain the ultimate authority over their resources. Performance analysis shows that our method adds very little overhead to the existing security infrastructure of OGSA-DAI
Managing vulnerabilities of information systems to security incidents (2003)

Information security-conscious managers of organizations have the responsibility to advise their senior management of the level of risks faced by the information systems. This requires managers to conduct vulnerability assessment as the first step of a risk analysis approach. However, a lack of real world data classification of security threats and develops a three-axis view of the threat space. It develops a scheme for probabilistic evaluation of impact of the security threats and proposes a risk management system consisting of a five-step approach. The goal is to assess the expected damages due to attacks, and managing the risk of attacks.
Variation in the human cannabinoid receptor CNR1 gene modulates gaze duration for happy faces (2011)

These results suggest that CNR1 variations modulate the striatal function that underlies the perception of signals of social reward, such as happy faces. This suggests that CNR1 is a key element in the molecular architecture of perception of certain basic emotions. This may have implications for understanding neurodevelopmental conditions marked by atypical eye contact and facial emotion processing, such as ASC.
<title>Renewable-reagent fiber optic sensor for ocean pCO<formula><inf><roman>2</roman></inf></formula></title> (1992)

A renewable-reagent fiber optic chemical sensor has been developed for measuring the partial pressure of carbon dioxide in ocean waters. A colorimetric pH indicator is delivered at a controlled flow rate through capillary tubing to the fiber tips. The fibers measure the color changes induced by CO<sub>2</sub> diffusion across a gas-permeable silicone membrane. Multi- wavelength detection is used to correct for system drift. Factors affecting the sensitivity and stability of the response are discussed.
High Resolution Cerebral Blood Flow Imaging by Registered Laser Speckle Contrast Analysis (2010)

Laser speckle imaging (LSI) has been widely used for in vivo detecting cerebral blood flow (CBF) under various physiological and pathological conditions. So far, nearly all literature on in vivo LSI does not consider the influence of disturbances due to respiration and/or heart beating of animals. In this paper, we analyze how such physiologic motions affect the spatial resolution of the conventional laser speckle contrast analysis (LASCA). We propose a registered laser speckle contrast analysis (rLASCA) method which first registers raw speckle images with a 3 x 3 convolution kernel, normalized correlation metric and cubic B-spline interpolator, and then constructs the contrast image for CBF. rLASCA not only significantly improves the distinguishability of small vessels, but also efficiently suppresses the noises induced by respiration and/or heart beating. In an application of imaging the angiogenesis of rat's brain tumor, rLASCA outperformed the conventional LASCA in providing a much higher resolution for new small vessels. As a processing method for LSI, rLASCA can be directly applied to other LSI experiments where the disturbances from different sources (like respiration, heart beating) exist.
Diastereoselective nucleophilic addition to coordinated cyclohexadienyl rings in chiral manganese complexes (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDiastereoselective nucleophilic addition to coordinated cyclohexadienyl rings in chiral manganese complexesR. D. Pike, W. J. Ryan, G. B. Carpenter, and D. A. SweigartCite this: J. Am. Chem. Soc. 1989, 111, 22, 8535–8537Publication Date (Print):October 1, 1989Publication History Published online1 May 2002Published inissue 1 October 1989https://pubs.acs.org/doi/10.1021/ja00204a046https://doi.org/10.1021/ja00204a046research-articleACS PublicationsRequest reuse permissionsArticle Views113Altmetric-Citations28LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
A QoS-Aware Intelligent Replica Management Architecture for Content Distribution in Peer-to-Peer Overlay Networks (2009)

The large scale content distribution systems were improved broadly using the replication techniques. The demanded contents can be brought closer to the clients by multiplying the source of information geographically, which in turn reduce both the access latency and the network traffic. The system scalability can be improved by distributing the load across multiple servers which is proposed by replication. If a copy of the requested object (e.g., a web page or an image) is located in its closer proximity then the clients would feel low access latency. Depending on the position of the replicas, the effectiveness of replication tends to a large extent. A QoS based overlay network architecture involving an intelligent replica placement algorithm is proposed in this paper. Its main goal is to improve the network utilization and fault tolerance of the P2P system. In addition to the replica placement, it also has a caching technique, to reduce the search latency. We are able to show that our proposed architecture attains less latency and better throughput with reduced bandwidth usage, through the simulation results.
Oncolysis of Prostate Cancers Induced by Vesicular Stomatitis Virus in PTEN Knockout Mice (2010)

Abstract Vesicular stomatitis virus (VSV) is an oncolytic virus which selectively infects and kills cancer cells. The goal of the present study was to determine the safety and efficacy of VSV treatment of prostate tumors that arise in situ in immunocompetent, transgenic prostate-specific PTEN-null (PTEN−/−) mice. Interferon-sensitive VSV(AV3 strain), which expresses luciferase, was injected intraprostatically into tumor-bearing PTEN−/− and control mice and then monitored for tissue bioluminescence over 96 hours. Virus readily dispersed throughout the bodies of mice after only 3 hours; however, it persisted at high levels for &gt;72 hours in PTEN−/− mice, but at relatively low levels and for only ∼48 hours in controls. Plaque assays provided a similar pattern, with much higher concentrations of replicating virus in prostates of PTEN−/− mice than in controls. Transient, low levels of virus were detected in the spleens of both groups. Apoptotic analyses by terminal deoxynucleotidyl transferase–mediated dUTP nick end labeling staining revealed that VSV(AV3) is able to selectively infect and kill prostate cells in PTEN−/− mice, while sparing normal cells in control mice. The primary mechanism for cell kill is apparently apoptotic oncolysis as opposed to neutrophil invasion as has been reported using xenograft models. These results suggest that control of locally advanced human prostate cancer may be achievable through intraprostatic injection and amplification of a safe oncolytic virus, such as VSV(AV3). Cancer Res; 70(4); 1367–76
Bondline Temperature Control for Joining Composites With an Embedded Heater (2015)

This paper applies estimation and control techniques to achieve the desired bondline temperature for out-of-autoclave, adhesive bonding of carbon-fiber composite components. Rather than heating the entire system to cure the adhesive, e.g., in an autoclave, this research uses controlled heating targeted at the bondline with an embedded heater. The main contribution of this work is control using estimates of the bondline temperature without embedded sensors and wiring (of materials not intrinsic to the system) that can lead to reduced bond strength. Sensors placed outside the bond region are used to accurately estimate the bondline temperature to within 2% of the temperature range over which the bondline temperature is changed. Experimental results show that the estimated temperature can be used with feedback to achieve the desired, bondline, time–temperature profile that is needed to cure the adhesive. Additionally, shear lap joint tensile tests show that the resulting joint strength is comparable to specimens bonded using an external heat blanket.
Solid-Phase Synthesis of Symmetrical 3,6-Bispeptide−Acridone Conjugates (2002)

[reaction: see text] A novel high-yielding method for the solid-phase synthesis of 3,6-bispeptide-acridone conjugates is reported. It involves initial coupling of bifunctionalized acridone to a resin-bound peptide followed by an on-bead site-site reaction to couple the second peptide. This method leads to clean symmetrical bispeptide derivatives and appears to be general. This strategy will enable the generation of a library of 3,6-bispeptide-acridones to be screened for selective binding to telomeric G-quadruplex DNA.
A New Method for Synthesis of 7‐Deoxytaxane Analogues by Hydrogenation of Δ<sup>6,7</sup>‐Taxane Derivatives. (2003)

Abstract For Abstract see ChemInform Abstract in Full Text.
Multiuser hybrid beamforming for max-min SINR problem under 60 GHz wireless channel (2014)

This paper investigates a typical optimization problem for 60 GHz multiuser hybrid beamforming, which is to maximize the minimal SINR over all of the considered subcarriers under a total power constraint. In order to reduce the complexity, two methods of using the fixed analog beamforming (ABF) weights are presented rather than traditional iterative methods, which are codebook-based method and singular value decomposition (SVD) based method. The performance of hybrid beamforming with the fixed ABF weights are evaluated by computer simulations and compared with that of using the existing iterative method. Channel model defined in IEEE 802.11ad is utilized in the simulation. Simulation results show that the average max-min SINR achieved by the presented methods of using the fixed ABF weights are close to or even higher than that of the iterative method.
Grid data generation from contour images by using Euclid distance transformation (2002)

A DEM generation method from a contour map is described, for which implementation is simple and accuracy is sufficient from practical viewpoint. In the proposed method, the Euclidean distance transformation is used to search the points on the contour from which a target point is interpolated. Further, the method does not require complete the closed contour condition. The conversion accuracy evaluated by comparing the result with a human-interpreted DEM is 0.369 m when the elevation interval between contours is 10 m for completely closed contours. Even for the open contours, the accuracy is 0.396 m which is not so much deteriorated from the closed contour case. Both of these figures are supposed to be sufficient for most kind of applications which require contour to DEM conversion.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Beamspace MIMO transceivers for low-complexity and near-optimal communication at mm-wave frequencies (2013)

Multiple-input multiple-output (MIMO) systems that exploit multi-antenna arrays and millimeter-wave systems operating in the 30-300GHz band offer synergistic opportunities for meeting the exploding data requirements of wireless networks. While combining these technologies offers the advantages of high-dimensional MIMO, it increases transceiver complexity dramatically in conventional MIMO approaches due to the large number of antennas required for optimal performance. On the other hand, the dimension of the communication subspace is typically much smaller than the system dimension in practice. By multiplexing data onto highly directional orthogonal beams, beamspace MIMO (B-MIMO) provides direct and near-optimum access to the low-dimensional communication subspace and dramatically lowers transceiver complexity when realized with analog beamforming. In this paper we present and analyze the capacity of several low-complexity B-MIMO transceivers for realizing multi-Gigabits/s speeds.
Out-of-Focus Projector Calibration Method with Distortion Correction on the Projection Plane in the Structured Light Three-Dimensional Measurement System (2017)

The three-dimensional measurement system with a binary defocusing technique is widely applied in diverse fields. The measurement accuracy is mainly determined by out-of-focus projector calibration accuracy. In this paper, a high-precision out-of-focus projector calibration method that is based on distortion correction on the projection plane and nonlinear optimization algorithm is proposed. To this end, the paper experimentally presents the principle that the projector has noticeable distortions outside its focus plane. In terms of this principle, the proposed method uses a high-order radial and tangential lens distortion representation on the projection plane to correct the calibration residuals caused by projection distortion. The final accuracy parameters of out-of-focus projector were obtained using a nonlinear optimization algorithm with good initial values, which were provided by coarsely calibrating the parameters of the out-of-focus projector on the focal and projection planes. Finally, the experimental results demonstrated that the proposed method can accuracy calibrate an out-of-focus projector, regardless of the amount of defocusing.
Industrial Terrorism and the Unmaking of New Deal Labor Law (2011)

The passage of the Wagner (National Labor Relations) Act of 1935 represented an unprecedented effort to guarantee American workers basic labor rights--the rights to organize unions, to provoke meaningful collective bargaining, and to strike. Previous attempts by workers and government administrators to realize these rights in the workplace met with extraordinary, often violent, resistance from powerful industrial employers, whose repressive measures were described by government officials as a system of "industrial terrorism." Although labor scholars have acknowledged these practices and paid some attention to the way they initially frustrated labor rights and influenced the jurisprudence and politics of labor relations in the late 1930s and early 1940s, the literature has neither adequately described the extent and intensity of this phenomenon nor fully explored its effects. This Article remedies that shortcoming. Focusing on three industries where the practice of industrial terrorism was especially well developed and its influence especially pronounced, this Article shows how the practitioners of industrial terrorism and their allies in Congress were able to turn the legacy of violence and disorder, which they authored by their violent resistance to the Wagner Act, into the basis of an extraordinary counterattack on labor rights. It shows how this attack culminated in 1947 with the enactment of the profoundly reactionary Taft-Hartley Act and remade the landscape of American labor relations.