gebhart/patrepeval huggingface dataset:
Stuck Pipe Prediction Using Automated Real-Time Modeling and Data Analysis (2016)

Abstract A real-time method is presented to predict impending stuck pipe with sufficient warning to prevent it. The new method uses automated analysis of real-time modeling coupled with real-time data analysis. It can be applied to all well types for any well operation including drilling, casing running, completion activities, and re-entries. The method uses leading indicators of stuck pipe that were identified using historical data sets of 36 stuck pipe incidents in the Eagle Ford, Utica, Permian, and Gulf of Mexico. Four case histories show the utility of the new method in four shale horizontal wells for both drilling and off-bottom operations. The new method combines two types of analysis: (1) deviation of real-time data from real-time model predictions using hydraulics and torque and drag (T&D) software, and (2) trend analysis (i.e., rate of change) of real-time data. Parameters used are pump pressure, flow rate, torque, rotary speed, hookload and drag, and weight on bit along with static inputs such as BHA and drillstring configuration and directional surveys. Additional parameters such as downhole ECD are used when available and improve the results. But the method is designed to monitor all well types and provide a stuck-pipe-risk log even using only basic instrumentation. A novel algorithm predicts the probability of stuck pipe which is presented in a real-time log. Results demonstrate there is no single leading indicator present in all stuck pipe incidents. Consequently, relying on a single specific pattern (such as increasing pump pressure at constant flow rate) leads to inability to predict stuck pipe in some cases. Our early detection method relies on multiple indicators to strengthen the likelihood of detecting an increase in stuck pipe while avoiding false alerts. Deviations of parameters from model predictions have been used with success in the past by experts but the new method provides contextual awareness and provides thresholds that automate the process. A key element is the use of filtering for rig activity. Rate of change calculations provide valuable insight into rapidly deteriorating wellbore conditions when deviation from model predictions does not respond quickly enough over a short depth or time interval. The detection method was tested on four historical wells in which four stuck pipe and two near-miss events occurred. Testing showed that an alert was generated, on average, 38 minutes before the event. There were no false alerts recorded in these wells.
L'huile d'Argan Argania spinosa (L.) skeels sapotaceae (1992)

L'huile d'Argan, Argania spinosa, (Sapotaceae) du Maroc est riche en acides oleique et linoleique. L'acide oleique se repartit de facon quasi equitable entre les trois positions de sn-glycerol. L'acide linoleique esterifie majoritairement la position sn-2, le reste se repartit egalement sur les deux autres positions. Les acides gras satures esterifient preferentiellement les positions externes, l'acide palmitique plutot la position sn-1 et l'acide stearique la position sn-3
Thermal property microscopy with frequency domain thermoreflectance (2013)

A thermal property microscopy technique based on frequency domain thermoreflectance (FDTR) is presented. In FDTR, a periodically modulated laser locally heats a sample while a second probe beam monitors the surface reflectivity, which is related to the thermal properties of the sample with an analytical model. Here, we extend FDTR into an imaging technique capable of producing micrometer-scale maps of several thermophysical properties simultaneously. Thermal phase images are recorded at multiple frequencies chosen for maximum sensitivity to thermal properties of interest according to a thermal model of the sample. The phase versus frequency curves are then fit point-by-point to obtain quantitative thermal property images of various combinations of thermal properties in multilayer samples, including the in-plane and cross-plane thermal conductivities, heat capacity, thermal interface conductance, and film thickness. An FDTR microscope based on two continuous-wave lasers is described, and a sensitivity analysis of the technique to different thermal properties is carried out. As a demonstration, we image ~3 nm of patterned titanium under 100 nm of gold on a silicon substrate, and simultaneously create maps of the thermal interface conductance and substrate thermal conductivity. Results confirm the potential of our technique for imaging and quantifying thermal properties of buried layers, indicating its utility for mapping thermal properties in integrated circuits.
Oxidative aromatische Kupplung und Scholl‐Reaktion im Vergleich (2013)

Abstract Läuft die durch AlCl 3 bei hoher Temperatur und auch durch FeCl 3 , MoCl 5 , PIFA oder K 3 [Fe(CN) 6 ] bei Raumtemperatur vermittelte, dehydrierende Kupplung aromatischer Verbindungen in allen Fällen nach dem gleichen Mechanismus ab? Durch die wachsende Bedeutung der Synthese aromatischer Verbindungen durch doppelte C‐H‐Aktivierung, die zu unterschiedlichen Biarylen führt, wird diese Frage dringlicher. Da einige dieser Reaktionen nur in Gegenwart nichtoxidierender Lewis‐Säuren ablaufen und andere nur in Gegenwart bestimmter Oxidationsmittel, wagen die Autoren die Hypothese, dass abhängig von der elektronischen Struktur der Substrate und der Natur des “Katalysators” zwei unterschiedliche Mechanismen ablaufen können. Der eine verläuft über ein Radikalkation als Intermediat, der andere über die Bildung eines Sigma‐Komplexes zwischen Säure und Substrat. Das Ziel dieses Aufsatzes ist es, weitere mechanistische Studien anzuregen, die zu einem eingehenden Verständnis dieses Phänomens führen sollen.
Mutations in the Gene That Encodes the F-Actin Binding Protein Anillin Cause FSGS (2014)

FSGS is characterized by segmental scarring of the glomerulus and is a leading cause of kidney failure. Identification of genes causing FSGS has improved our understanding of disease mechanisms and points to defects in the glomerular epithelial cell, the podocyte, as a major factor in disease pathogenesis. Using a combination of genome-wide linkage studies and whole-exome sequencing in a kindred with familial FSGS, we identified a missense mutation R431C in anillin (ANLN), an F-actin binding cell cycle gene, as a cause of FSGS. We screened 250 additional families with FSGS and found another variant, G618C, that segregates with disease in a second family with FSGS. We demonstrate upregulation of anillin in podocytes in kidney biopsy specimens from individuals with FSGS and kidney samples from a murine model of HIV-1-associated nephropathy. Overexpression of R431C mutant ANLN in immortalized human podocytes results in enhanced podocyte motility. The mutant anillin displays reduced binding to the slit diaphragm-associated scaffold protein CD2AP. Knockdown of the ANLN gene in zebrafish morphants caused a loss of glomerular filtration barrier integrity, podocyte foot process effacement, and an edematous phenotype. Collectively, these findings suggest that anillin is important in maintaining the integrity of the podocyte actin cytoskeleton.
A wide-band mixer for WCDMA/CDMA2000 in 90nm digital CMOS process (2005)

A wide-band mixer with high linearity and insensitive to process and temperature variations, intended for used in WCDMA and CDMA2000 receivers, is implemented in a 90 nm digital CMOS process. The measurement data consistently show greater than 7 dBm of IIP3 and 52 dBm of IIP2 in both low and high frequency bands. In the low frequency band, the variation of IIP3 and IIP2 over the temperature range from -20/spl deg/C to 80/spl deg/C is only 0.2 dB and 2.2 dB respectively. The whole mixer for I/Q, including LO divider and LO buffer, consumes less than 8 mA in the low band and 13 mA in the high bands.
Mechanism for low-temperature photoluminescence in GaNAs/GaAs structures grown by molecular-beam epitaxy (1999)

The mechanism for low-temperature photoluminescence (PL) emissions in GaNAs epilayers and GaAs/GaNxAs1−x quantum well (QW) structures grown by molecular-beam epitaxy is studied in detail, employing PL, PL excitation, and time-resolved PL spectroscopies. It is shown that even though quantum confinement causes a strong blueshift of the GaNAs PL emission, its major characteristic properties are identical in both QW structures and epilayers. Based on the analysis of the PL line shape, its dependence on the excitation power and measurement temperature, as well as transient data, the PL emission is concluded to be caused by a recombination of excitons trapped by potential fluctuations in GaNAs.
Mapping of Linear B-Cell Epitopes on the Major Core Protein p24 of Human Immunodeficiency Virus Type 1 (HIV-1) (1992)

Three murine monoclonal antibodies (MAbs) F5-2, F5-4, and F5-16 defining three different epitopes on the major core protein p24 of the human immunodeficiency virus type 1 (HIV-1) were epitope mapped using a random fragment expression library representing the p17- and p24-encoding part of the gag open reading frame. F5-2 defined an epitope within amino acids (aa) 14-23 at the N-terminus of p24, and F5-4 defined an epitope within aa 153-174 in the C-terminus of p24. F5-16 did not recognize any of the fusion proteins produced by the expression library indicating that this MAb defines a true conformational epitope on p24. Since the N-terminus of p24 has been reported to be immunosilent in humans, 356 HIV-1 antibody-positive serum samples were tested for reactivity against the region of p24 defined by F5-2. More than one third of the samples recognized this region indicating that it is immunoreactive and, further, the presence of antibodies against this region was associated with a reduced CD4 cell count.
Efficacy of spinal cord stimulation: 10 years of experience in a pain centre in Belgium (2001)

Spinal cord stimulation is a minimally invasive mode of treatment in the management of certain forms of chronic pain that do not respond to conventional pain therapy. Several authors have reported encouraging findings with this technique. Over a 10-year period in a single centre, 254 patients were subjected to a trial period of spinal cord stimulation with an externalized pulse generator. Two hundred and seventeen of the patients showed satisfactory results justifying permanent implantation of a spinal cord stimulation system. In 1998, an independent physician invited 153 patients (155 pain cases), who still had the system in place and who could be contacted, for an interview. The aim of this study was to evaluate the efficacy of an implanted spinal cord stimulation system in terms of pain relief and quality of life and to assess the accuracy of the patient selection criteria. The results of this study demonstrate a high success rate as evaluated by the patients' own assessments--68% of the patients rated the result of the treatment as excellent to good after an average follow-up of almost 4 years. The resumption of work by 31% of patients who had been working before the onset of pain supports these positive findings.
Lions and Tigers and Bears: Capturing Non-rigid, 3D, Articulated Shape from Images (2018)

Animals are widespread in nature and the analysis of their shape and motion is important in many fields and industries. Modeling 3D animal shape, however, is difficult because the 3D scanning methods used to capture human shape are not applicable to wild animals or natural settings. Consequently, we propose a method to capture the detailed 3D shape of animals from images alone. The articulated and deformable nature of animals makes this problem extremely challenging, particularly in unconstrained environments with moving and uncalibrated cameras. To make this possible, we use a strong prior model of articulated animal shape that we fit to the image data. We then deform the animal shape in a canonical reference pose such that it matches image evidence when articulated and projected into multiple images. Our method extracts significantly more 3D shape detail than previous methods and is able to model new species, including the shape of an extinct animal, using only a few video frames. Additionally, the projected 3D shapes are accurate enough to facilitate the extraction of a realistic texture map from multiple frames.
Off-Time Control of <italic>LLC</italic> Resonant Half-Bridge Converter to Prevent Audible Noise Generation Under a Light-Load Condition (2017)

This paper presents a control method that can prevent audible noise generation in an LLC resonant half-bridge dc-dc converter under a light-load condition, while achieving the same input voltage range and power-conversion efficiency ηe as the burst-control method that generates an audible noise. The proposed method reduces switching and conduction losses at light load by skipping several pairs of switch-control pulses, while varying the switching frequency less than the normal-control method does. This skip-control method enables the LLC resonant converter to have a large magnetizing inductance, and to have high η <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">e</sub> over a wide range of load variation. At an input voltage of 385 V, an output voltage of 24 V, and a resonant frequency of 180 kHz, the proposed method achieved η e ≥ 85.46% for an output power range of 7.2-360 W; the highest η <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">e</sub> was 96.08% at P <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">o</sub> = 336 W.
A Herpesviral Lytic Protein Regulates the Structure of Latent Viral Chromatin (2016)

Latent infection by viruses usually involves minimizing viral protein synthesis so that the host immune system cannot recognize the infected cells and eliminate them. Herpes simplex virus has been thought to express only noncoding RNAs as abundant gene products during latency. In this study, we found genetic evidence that an HSV lytic protein is functional during latent infection, and this protein may provide a new target for antivirals that target both lytic and latent infections.
SAFETY AND SECURITY IS EVERYONE'S BUSINESS. (2017)

Workplace safety and security should be a given but as we all know this is not always the case.
Direct-write ALD of In2O3:H using a μ-plasma printer (2016)

We demonstrate direct-write[1]ALD of In2O3:H patterns with good selectivity on large area substrates. The nucleation delay on H-terminated surfaces is exploited to achieve area selective deposition w/o any subtractive step (e.g. etching, SAMs, litho, lift-off). Selectivity is achieved by tailoring the surface groups using a μ-plasma printer with an oxygen-based plasma-chemistry.
A CMOS time to digital converter VLSI for high-energy physics (1988)

A Time to Digital Converter VLSI chip for high-energy physics experiment is developed. A low-power and high-density characteristics of the chip are attained by using submicron CMOS process and a new circuit technique which use memory cells and gate delay. In order to achieve excellent stability of time measurement, an internal feed-back circuit is also introduced.
Hierarchical Carbon–Nitrogen Architectures with Both Mesopores and Macrochannels as Excellent Cathodes for Rechargeable Li–O<sub>2</sub> Batteries (2014)

Lithium–oxygen batteries are attracting more and more interest; however, their poor rechargeability and low efficiency remain critical barriers to practical applications. Herein, hierarchical carbon–nitrogen architectures with both macrochannels and mesopores are prepared through an economical and environmentally benign sol–gel route, which show high electrocatalytic activity and stable cyclability over 160 cycles as cathodes for Li–O 2 batteries. Such good performance owes to the coexistence of macrochannels and mesopores in C–N hierarchical architectures, which greatly facilitate the Li + diffusion and electrolyte immersion, as well as provide an effective space for O 2 diffusion and O 2 /Li 2 O 2 conversion. Additionally, the mechanism of oxygen reduction reactions is discussed with the N‐rich carbon materials through first‐principles computations. The lithiated pyridinic N provides excellent O 2 adsorption and activation sites, and thus catalyzes the electrode processes. Therefore, hierarchical carbon–nitrogen architectures with both macrochannels and mesopores are promising cathodes for Li–O 2 batteries.
Photonic-crystal near-ultraviolet reflectance filters fabricated by nanoreplica molding (2006)

One-dimensional photonic-crystal reflectance filters operating in the near-ultraviolet wavelengths were fabricated using nanoreplica molding from a silicon surface structure “master” template, patterned using electron-beam lithography. The fabricated devices produce a narrow linewidth reflectance resonance at a wavelength of 411nm for TM polarized illumination and a broadband reflectance characteristic between 402 and 439nm for TE polarized illumination. The measured reflectance spectra are accurately predicted by Rigorous Coupled Wave Analysis computer simulations, which demonstrate the capability for designing similar filter performance for wavelengths &lt;350nm through minor adjustment of the photonic-crystal lattice period.
Prior irinotecan exposure does not preclude benefit to liposomal irinotecan in patients with metastatic pancreatic ductal adenocarcinoma (2023)

Prior irinotecan was not found to be a significant predictor of patient outcomes in those later treated with liposomal irinotecan. Thus, the results may inform the rationale for utilizing liposomal irinotecan combination therapy following prior irinotecan exposure in mPDAC, in particular where the prior irinotecan exposure was more distant in time.
High‐Speed Flexible Organic Field‐Effect Transistors with a 3D Structure (2011)

High-speed, flexible organic field-effect transistors with a 3D structure are fabricated on a plastic substrate in which vertical channels are formed to realize high response speed. With the benefit of short channel lengths, the fabricated transistors show fast dynamic switching within 250 ns, which corresponds to 4 MHz operation, even with the modest carrier mobility of 0.2 cm2 V−1 s−1 in organic semiconductors deposited on the vertical sidewalls.
Thermally activated delayed fluorescence blue dopants and hosts: from the design strategy to organic light-emitting diode applications (2016)

Thermally activated delayed fluorescence materials exhibited outstanding external quantum efficiencies in OLEDs along with good CIE color coordinates and improved device stabilities. Hence these are most promising for commercialization of OLEDs.
Iterators, Schedulers, and Distributed-memory Parallelism (1996)

In previous work, we demonstrated the advantages of encapsulating query evaluation algorithms as ‘iterators’ for sequential and parallel query evaluation. Unfortunately, those earlier models have a severe drawback with respect to resource allocation in distributed-memory systems. Since threads may be initiated long before they actually perform useful work, thread placement decisions may be suboptimal. In this paper, we briefly review the iterator model and then extend it to support bottom-up, just-in-time activation of appropriate query plan fragments as well as local and global synchronization and communication among sibling threads. Some of the algorithms described here may seem intricate; however, the intricacy is encapsulated entirely in the parallelism or ‘exchange’ iterator, thus freeing developers of data manipulation iterators to focus on the specific algorithms at hand, instead of on mechanisms for parallelism. Moreoever, code fragments extracted from an operational prototype demonstrate the ease with which our suggestions can be implemented. Run-time overhead and performance of our techniques are identical to those of earlier, less extensible techniques for bottom-up activation; the benefits of the presented techniques are their clean design, abstraction, extensibility, and the resulting ease of maintenance and enhancement.
A dataset on 145 chemicals tested in alternative assays for skin sensitization undergoing prevalidation (2013)

Skin sensitization is a key endpoint for cosmetic ingredients, with a forthcoming ban for animal testing in Europe. Four alternative tests have so far been submitted to ECVAM prevalidation: (i) MUSST and (ii) h-Clat assess surface markers on dendritic cell lines, (iii) the direct peptide reactivity assay (DPRA) measures reactivity with model peptides and (iv) the KeratinoSens(TM) assay which is based on detection of Nrf2-induced luciferase. It is anticipated that only an integrated testing strategy (ITS) based on a battery of tests might give a full replacement providing also a sensitization potency assessment, but this concept should be tested with a data-driven analysis. Here we report a database on 145 chemicals reporting the quantitative endpoints measured in a U937- test, the DPRA and KeratinoSens(TM) . It can serve to develop data-driven ITS approaches as we show in a parallel paper and provides a view as to the current ability to predict with in vitro tests as we are entering 2013. It may also serve as reference database when benchmarking new molecules with in vitro based read-across and find use as a reference database when evaluating new tests. The tests and combinations thereof were evaluated for predictivity, and overall a similar predictivity was found as before on three-fold smaller datasets. Analysis of the dose-response parameters of the individual tests indicates a correlation to sensitization potency. Detailed analysis of chemicals false-negative and false-positive in two tests helped to define limitations in the tests but also in the database derived from animal studies.
Synthesis of halodimethoxy-1,2-benzoquinones (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of halodimethoxy-1,2-benzoquinonesUlrich Wriede, Mario Fernandez, Kevin F. West, Dale Harcour, and Harold W. MooreCite this: J. Org. Chem. 1987, 52, 20, 4485–4489Publication Date (Print):October 1, 1987Publication History Published online1 May 2002Published inissue 1 October 1987https://pubs.acs.org/doi/10.1021/jo00229a011https://doi.org/10.1021/jo00229a011research-articleACS PublicationsRequest reuse permissionsArticle Views2361Altmetric-Citations50LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts