gebhart/patrepeval huggingface dataset:
[1-(.beta.-mercapto-.beta.,.beta.-cyclopentamethylenepropionic acid),2-(O-methyl)tyrosine]arginine-vasopressin and [1-(.beta.-mercapto-.beta.,.beta.-cyclopentamethylenepropionic acid)]arginine-vasopressin, two highly potent antagonists of the vasopressor response to arginine-vasopressin (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT[1-(.beta.-mercapto-.beta.,.beta.-cyclopentamethylenepropionic acid),2-(O-methyl)tyrosine]arginine-vasopressin and [1-(.beta.-mercapto-.beta.,.beta.-cyclopentamethylenepropionic acid)]arginine-vasopressin, two highly potent antagonists of the vasopressor response to arginine-vasopressinMarian Kruszynski, Bernard Lammek, Maurice Manning, Janny Seto, Jaya Haldar, and Wilbur H. SawyerCite this: J. Med. Chem. 1980, 23, 4, 364–368Publication Date (Print):April 1, 1980Publication History Published online1 May 2002Published inissue 1 April 1980https://doi.org/10.1021/jm00178a003RIGHTS & PERMISSIONSArticle Views215Altmetric-Citations358LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (730 KB) Get e-Alerts Get e-Alerts
Multigrained modeling with pattern specific maximum likelihood transformations for text-independent speaker recognition (2003)

We present a transformation-based, multigrained data modeling technique in the context of text independent speaker recognition, aimed at mitigating difficulties caused by sparse training and test data. Both identification and verification are addressed, where we view the entire population as divided into the target population and its complement, which we refer to as the background population. First, we present our development of maximum likelihood transformation based recognition with diagonally constrained Gaussian mixture models and show its robustness to data scarcity with results on identification. Then for each target and background speaker, a multigrained model is constructed using the transformation based extension as a building block. The training data is labeled with an HMM based phone labeler. We then make use of a graduated phone class structure to train the speaker model at various levels of detail. This structure is a tree with the root node containing all the phones. Subsequent levels partition the phones into increasingly finer grained linguistic classes. This method affords the use of fine detail where possible, i.e., as reflected in the amount of training data distributed to each tree node. We demonstrate the effectiveness of the modeling with verification experiments in matched and mismatched conditions.
Probe field enhancement in photonic crystals by upconversion nanoparticles (2011)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Jingyu Zhang, Teresa E. Pick, Daniel Gargas, Scott Dhuey, Emory M. Chan, Ying Wu, Xiaogan Liang, P. James Schuck, Deirdre L. Olynick, Brett A. Helms, Stefano Cabrini; Probe field enhancement in photonic crystals by upconversion nanoparticles. Journal of Vacuum Science & Technology B 1 November 2011; 29 (6): 06F403. https://doi.org/10.1116/1.3662086 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAVS: Science & Technology of Materials Interfaces and ProcessingJournal of Vacuum Science & Technology B Search Advanced Search |Citation Search
Exciting Engineered Passive Dynamics in a Bipedal Robot (2015)

A common approach in designing legged robots is to build fully actuated machines and control the machine dynamics entirely in software, carefully avoiding impacts and expending a lot of energy. However, these machines are outperformed by their human and animal counterparts. Animals achieve their impressive agility, efficiency, and robustness through a close integration of passive dynamics, implemented through mechanical components, and neural control. Robots can benefit from this same integrated approach, but a strong theoretical framework is required to design the passive dynamics of a machine and exploit them for control. For this framework, we use a bipedal spring-mass model, which has been shown to approximate the dynamics of human locomotion. This paper reports the first implementation of spring-mass walking on a bipedal robot. We present the use of template dynamics as a control objective exploiting the engineered passive spring-mass dynamics of the ATRIAS robot. The results highlight the benefits of combining passive dynamics with dynamics-based control and open up a library of spring-mass model-based control strategies for dynamic gait control of robots.
Potential Treatment of Fatty Liver with 14-Day Subcutaneous Injections of Glucagon (2003)

Fatty liver is a major metabolic disease of dairy cows in early lactation that can be treated with 14-d continuous, intravenous infusions of 10 mg/d of glucagon. The objective was to test whether similar effects can be obtained with 14-d subcutaneous 7.5- or 15-mg daily dosages of glucagon beginning at d 8 postpartum. Multiparous Holstein cows (n = 32) were grouped on the basis of their liver triacylglycerol concentration at d 8 postpartum into "normal" (n = 8; triacylglycerol < 1% liver wet wt) and "susceptible" (n = 24; triacylglycerol > 1% liver wet wt) cows. Susceptible cows were assigned randomly to three groups and beginning at d 8 postpartum received 0, 2.5, or 5 mg of glucagon in 60 ml of saline by subcutaneous injections every 8 h for 14 d. Beginning at d 8 postpartum, normal cows received 60 ml of saline by subcutaneous injections every 8 h for 14 d. Both dosages of glucagon increased concentrations of plasma glucose and insulin and decreased concentrations of plasma nonesterfied fatty acids. Glucagon injections of 15 mg/d decreased concentrations of liver triacylglycerol in cows older than 3.5 yr, but not in younger multiparous cows. Our results document that subcutaneous injections of glucagon have the potential to decrease the degree of fatty liver in older dairy cows in early lactation.
Quality of Sensor-Originated Information in Coalition Information Networks (2010)

Coalition operations greatly benefit from the exchange of information collected from a plethora of wirelessly communicating sensors deployed in the theater of operation. However, to make judicious use of this information and then act effectively based on this information, knowledge of its quality, and a common means of expressing and communicating this quality are necessary. This chapter considers quality of information (QoI) for sensor networks starting with building a definition of QoI from first principles and by exploiting industry efforts to define quality in other domains, notably quality of service. The definition touches upon two complementary yet distinct aspects of quality: (a) the inherent quality attributes that characterize information; and (b) the assessment of these attributes within the context of applications utilizing the information, referred as the value of information (VoI). It then discusses information as a service and the various QoI viewpoints that associate sensor-originated information providers with sensor-enabled applications in dynamic coalition environments. Then, information processors and operators are introduced, which are functional modules in end-to-end systems that process information based on the QoI attributes. Finally, a data model for QoI metadata, describing the QoI attributes, is presented. The data model provides a common means to describe and communicate QoI attributes among information processors. It enables the indexing and searching of the most pertinent information, of desired quality, and information sources and the on-demand binding of applications to sources that is necessary to support operations in multiparty coalitions.
Optical Measure of Enamel Health: Ability to Triage High Risk Children in Communities without Dental Practitioners (2012)

As prevalence of dental caries in children rises worldwide, there is an increasing need for a safe, easy to use and cost-effective technique to detect and identify childhood caries at an early stage where remineralization of the tooth is possible and damage may be reversed. We have developed a simple and robust autofluorescence (AF) laboratory device that uses the dental AF spectra from 405 nm and 532 nm laser excitation and computes a ratio of the integrated areas of the spectra. Ten human extracted teeth with early stage natural caries lesions and an additional 8 human extracted teeth with artificially created erosion lesions were used for the study. The 405/532 nm AF ratio was obtained from healthy as well as unhealthy enamel regions for all teeth. A clear distinction between the ratios for healthy enamel and unhealthy enamel was seen. A percent change in 405/532 nm AF ratio of 62% was seen between natural white spot lesions and healthy enamel, with progressively more severe lesions leading to greater percent changes in AF ratios. The 405/532 nm AF ratio is a promising technique that may be used to detect the presence of early stage dental caries and triage high risk children. A cost effective clinical device can be developed which utilizes the proposed technique to screen children in underserved communities.
<title>Highly efficient polarized Er-doped superfluorescent fiber source</title> (1996)

We report the experimental demonstration of a polarized superfluorescent fiber source (SFS) made by inserting a low- loss polarizer at an optimum position along the erbium-doped fiber of a standards SFS. This source produces a strongly polarized output with nearly the same output power as a standard, unpolarized SFS. We show good agreement between the behavior of the source and numerical simulations.
Simulation of Coulomb interactions in electron projection lithography using scattering contrast (2002)

Electron projection lithography (EPL), such as PREVAIL and SCALPEL, are among the candidates for next generation lithography. We modified the discrete Coulomb interaction simulator BOERSCH to be capable of incorporating the treatment of mask-scattered electrons into the simulation domain. Annular apertures of arbitrary number and size also can be set as the limiting aperture in addition to the usual round shape. Using this simulator, not only the resolution but also the performance of the SCALPEL GHOST proximity effect correction (PEC) can be evaluated. Therefore, this modified BOERSCH can provide almost perfect functions necessary for the EPL process development.
Capacitive micromachined ultrasonic transducer technology for medical ultrasound imaging (2005)

Capacitive micromachined ultrasonic transducer (cMUT) technology has been recognized as an attractive alternative to the more traditional piezoelectric transducer technology in medical ultrasound imaging for several years now. There are mainly two reasons for the interest in this technology: Micromachining is derived from the integrated circuit technology and therefore shares the well-known advantages and experience of it. Also, capacitive transduction using thin membranes has fundamental superiorities over the piezoelectric transduction mechanism such as wide frequency bandwidth. Capacitive micromachined ultrasonic transducers are essentially capacitor cells where the two plates of the capacitor, the membrane and the substrate, are separated with a vacuum sealed cavity. Typically, a cMUT is made of many micro-scale capacitor cells operating in parallel. This paper describes a new fabrication technique for building cMUTs which is called the wafer-bonding method. In this method, the cavity and the membrane are defined on separate wafers and brought together by wafer-bonding in vacuum. The wafer-bonding method has several advantages over the traditional sacrificial release method of cMUT fabrication. It allows greater flexibility in the cMUT design which means better device performance. It reduces the number of process steps, device turn-around time, and increases the overall uniformity, reliability. and repeatability. Device examples of one-dimensional and two-dimensional arrays designed to work in the 1 to 50 MHz range with 100% fractional bandwidth highlight the advantages of this method, and show that cMUT technology is indeed the better candidate for next generation ultrasonic imaging arrays.
Laser-excited photoemission spectroscopy study of superconducting boron-doped diamond (2006)

We have investigated the low–energy electronic state of boron-doped diamond thin film by the laser–excited photoemission spectroscopy. A clear Fermi–edge is observed for samples doped above the semiconductor–metal boundary, together with the characteristic structures at 150 × n meV possibly due to the strong electron–lattice coupling effect. In addition, for the superconducting sample, we observed a shift of the leading edge below Tc indicative of a superconducting gap opening. We discuss the electron–lattice coupling and the superconductivity in doped diamond.
Characterisation of tissue shrinkage during microwave thermal ablation (2014)

In addition to an asymmetric substantial shrinkage of the ablated tissue volume, an initial expansion phenomenon occurs during MW ablation. Thus, complex modifications of the tissue close to a radiating antenna will likely need to be taken into account for future methods of real-time ablation monitoring.
The Feasibility of Injecting Inaudible Voice Commands to Voice Assistants (2019)

Voice assistants (VAs) such as Siri and Google Now have become an increasingly popular human-machine interaction method and have made various systems voice controllable. Prior work on attacking voice assistants shows that the hidden voice commands that are incomprehensible to people can control the VAs. Hidden voice commands, though `hidden', are nonetheless audible. In this work, we design a completely inaudible attack, DolphinAttack, that modulates voice commands on ultrasonic carriers to achieve inaudibility. By leveraging the nonlinearity of the microphone circuits, the modulated low-frequency audio commands can be successfully demodulated, recovered, and more importantly interpreted by the voice assistants. We validate DolphinAttack on popular voice assistants, including Siri, Google Now, S Voice, HiVoice, Cortana, Alexa, etc. By injecting a sequence of inaudible voice commands, we show a few proof-of-concept attacks, which include activating Siri to initiate a FaceTime call on iPhone, activating Google Now to turn on the airplane mode, and even manipulating the navigation system in an Audi automobile. We propose hardware and software defense solutions. We validate that it is feasible to detect DolphinAttack by classifying the audios using supported vector machine (SVM), and suggest to re-design voice assistants to be resilient to inaudible voice command attacks.
Multi-mechanism vibration harvester combining inductive and piezoelectric mechanisms (2012)

With increasing demand for wireless sensor nodes in automobile, aircraft and rail applications, the need for energy harvesters has been growing. In these applications, energy harvesters provide a more robust and inexpensive power solution than batteries. In order to enhance the power density of existing energy harvesters, a variety of multimodal energy harvesting techniques have been proposed. Multi-modal energy harvesters can be categorized as: (i) Multi-Source Energy Harvester (MSEH), (ii) Multi-Mechanism Energy Harvester (MMEH), and (iii) Single Source Multi-Mode Energy Harvester (S<sup>2</sup>M<sup>2</sup>EH). In this study, we focus on developing MMEH which combines the inductive and piezoelectric mechanisms. The multi-mechanism harvester was modeled using FEM techniques and theoretically analyzed to optimize the performance and reduce the overall shape and size similar to that of AA battery. The theoretical model combining analytical and FEM modeling techniques provides the system dynamics and output power for specific generator and cymbal geometry at various source conditions. In the proposed design, a cylindrical tube contains a magnetic levitation cavity where a center magnet oscillates through a copper coil. Piezoelectric cymbal transducers were mounted on the top and bottom sections of the cylindrical shell. In response to the external vibrations, electrical energy was harvested from the relative motion between magnet and coil through Faraday's effect and from the piezoelectric material through the direct piezoelectric effect. Experimental results validate the predictions from theoretical model and show the promise of multimodal harvester for powering wireless sensor nodes in automobile, aircraft, and rail applications.
Addition of platelet concentrate to Dermo-Epidermal Skin Graft in deep burn trauma reduces scarring and need for revision surgeries (2013)

Our findings indicate that DESG engraftment is facilitated by the local addition of platelets and by systemic thrombocytosis. This local interaction leads to the physiological revascularization at 1-3 months. We observed significant elevation of circulating platelets in early stages of engraftment (1-7 days), which normalized over the subsequent 7 and 90 days.
Middle ear mucosal regeneration with three-dimensionally tissue-engineered autologous middle ear cell sheets in rabbit model (2013)

The likelihood of recurrent retraction and adhesion of newly formed tympanic membrane is high when middle ear mucosa is extensively lost during cholesteatoma and adhesive otitis media surgery. If rapid postoperative regeneration of the mucosa on the exposed bone surface can be achieved, prevention of recurrent eardrum adhesion and cholesteatoma formation, for which there has been no definitive treatment, can be expected. Suture-less transplantation of tissue-engineered mucosal cell sheets was examined immediately after the operation of otitis media surgery in order to quickly regenerate middle ear mucosa lost during surgery in a rabbit model. Transplantable middle ear mucosal cell sheets with a three-dimensional tissue architecture very similar to native middle ear mucosa were fabricated from middle ear mucosal tissue fragments obtained in an autologous manner from middle ear bulla on temperature-responsive culture surfaces. Immediately after the mucosa was resected from middle ear bone bulla inner cavity, mucosal cell sheets were grafted at the resected site. Both bone hyperplasia and granulation tissue formation were inhibited and early mucosal regeneration was observed in the cell sheet-grafted group, compared with the control group in which only mucosal removal was carried out and the bone surface exposed. This result indicates that tissue engineered mucosal cell sheets would be useful to minimize complications after the surgical operation on otitis media and future clinical application is expected.
High-Performance Mass Spectrometry: Fourier Transform Ion Cyclotron Resonance at 14.5 Tesla (2008)

We describe the design and current performance of a 14.5 T hybrid linear quadrupole ion trap Fourier transform ion cyclotron resonance mass spectrometer. Ion masses are routinely determined at 4-fold better mass accuracy and 2-fold higher resolving power than similar 7 T systems at the same scan rate. The combination of high magnetic field and strict control of the number of trapped ions results in external calibration broadband mass accuracy typically less than 300 ppb rms, and a resolving power of 200,000 (m/Delta m50% at m/z 400) is achieved at greater than 1 mass spectrum per second. Novel ion storage optics and methodology increase the maximum number of ions that can be delivered to the FTICR cell, thereby improving dynamic range for tandem mass spectrometry and complex mixture applications.
Configuring DHCP leases in the smartphone era (2012)

The Dynamic Host Configuration Protocol (DHCP) was introduced nearly 20 years ago as a mechanism for hosts to automatically acquire IP addresses. While the protocol remains the same, its usage has evolved, especially in the last decade with the introduction of mobile devices and wireless local area networks. In this paper we investigate the impact that new types of wireless devices, such as smartphones, have on DHCP. We use two one-month long traces, collected at a corporate and an educational network, and we compare side-by-side DHCP usage patterns. We develop a novel passive fingerprinting technique based on DHCP messages to determine the device type and operating system. We show that DHCP implementations vary among device types and have an effect on DHCP lease durations. To improve network address utilization, without introducing any protocol changes, we propose a new leasing strategy which takes into account device types. This strategy, compared to current approaches, improves the address utilization without considerably increasing DHCP overhead.
MOST: multiplexed optical scanner technology (2002)

Using the NLC design philosophy, this paper introduces a novel optical scanning method called "multiplexed optical scanner technology" or "MOST' that has the fundamental capabilities to realize the desired scanner. Specifically, four types of multiplexed optical scanners (MOSs), namely, the polarization or P-MOS, the time or T-MOS, the wavelength or W-MOS, and the code or C-MOS are highlighted. In effect, independent exploitation of polarization, time, wavelength, and optical code switching is used to access 3-D phase perturbations stored in large area phase sensitive photothermal programmable NLC devices inorder to realize a high speed optical scanner.
Improved combined binary/decimal fixed-point multipliers (2008)

Decimal multiplication is important in many commercial applications including banking, tax calculation, currency conversion, and other financial areas. This paper presents several combined binary/decimal fixed-point multipliers that use the BCD-4221 recoding for the decimal digits. This allows the use of binary carry-save hardware to perform decimal addition with a small correction. Our proposed designs contain several novel improvements over previously published designs. These include an improved reduction tree organization to reduce the area and delay of the multiplier and improved reduction tree components that leverage the redundant decimal encodings to help reduce delay. A novel split reduction tree architecture is also introduced that reduces the delay of the binary product with only a small increase in total area. Area and delay estimates are presented that show that the proposed designs have significant area improvements over separate binary and decimal multipliers while still maintaining similar latencies for both decimal and binary operations.