gebhart/patrepeval huggingface dataset:
Acoustic Surveillance of Production Impairment With Real-Time Completion Monitoring (2008)

Abstract Deepwater production is challenged by well underperformance problems that are hard to diagnose early on and expensive to deal with later. Problems are amplified by reliance on few complex wells with sophisticated sand control media. New downhole data is required for better understanding and prevention of completion and formation damage. We introduce Real-Time Completion Monitoring (RTCM), a new non-intrusive surveillance method for identifying impairment in sand-screened completions that utilizes acoustic signals sent via the fluid column. These signals are carried by tube waves that move borehole fluid back and forth radially across the completion layers. Such tube waves are capable of "instant" testing of the presence or absence of fluid communication across the completion and are sensitive to changes occurring in sand screens, gravel sand, perforations, and possibly reservoir. The part of the completion that has different impairment from its neighbors will carry tube waves with modified signatures (velocity, attenuation) and also would produce a reflection from the boundary where impairment changes. The method relies on permanent acoustic sensors performing acoustic soundings at the start of production and then repeating these measurements during the life of the well. Thus, it could be thought of as "miniaturized" 4D seismic and "permanent log" in an individual wellbore. In the meantime repeated conventional wireline measurements can be performed to assess the completion permeability.
Characterization of eukaryotic initiation factor 4A, a protein involved in ATP-dependent binding of globin mRNA. (1982)

Eukaryotic initiation factor 4A (eIF-4A) has been purified (to apparent homogeneity) from rabbit reticulocyte lysate. It is a single polypeptide accounting for at least 90% of the Coomassie blue staining material when subjected to gel electrophoresis in the presence of sodium dodecyl sulfate. The molecular weight was determined by gel electrophoresis under denaturing conditions at two different bisacrylamide to acrylamide ratios, by gel filtration under native conditions and by sedimentation equilibrium at three different protein concentrations. Additional physical properties of the polypeptide were also determined. In an attempt to characterize the function of eIF-4A, a protein specifically required for mRNA translation, an assay was developed which measures the protein-dependent retention of radiolabeled hemoglobin mRNA on nitrocellulose filters. These studies led to the discovery of an ATP-stimulated binding of mRNA which is dependent on the presence of eIF-4A and eIF-4B that also contains the 24,000-dalton cap binding protein. The reaction apparently requires ATP hydrolysis since a nonhydrolyzable analogue of ATP, adenosine 5'-(beta, gamma-imino)triphosphate, does not stimulate mRNA binding and GTP cannot substitute for ATP. In addition, ATP-stimulated binding of mRNA can be inhibited by an analog of the mRNA 5' terminus, m7GMP, suggesting recognition of the capped 5' end of hemoglobin mRNA. Consistent with this suggestion, ATP also stimulated the covalent cross-linking of eIF-4A and eIF-4B to the cap of oxidized reovirus mRNA, an interaction that was inhibited by m7GDP.
The Cyclooxygenase-2 Inhibitor Etoricoxib Is a Potent Chemopreventive Agent of Colon Carcinogenesis in the Rat Model (2009)

Cyclooxygenase-2 (COX-2), an inducible prostaglandin G/H synthase, is overexpressed in several human cancers, including colon cancer, and therefore the potential ability of a selective COX-2 inhibitor, etoricoxib, is considered in the prevention of the 1,2-dimethyl hydrazine (DMH)-induced colon carcinogenesis in the rat model. DMH was injected s.c. for 6 weeks, whereas etoricoxib was fed orally to the rats on a daily basis. The results showed that DMH produced a very high number of multiple plaque lesions (MPLs), putative neoplastic biomarkers, localized throughout the colon, whereas considerable regression was observed with etoricoxib treatment. In addition, the etoricoxib group was the only group that exhibited very few of these lesions. Histopathological analysis revealed extreme dysplasia, a few adenomas, and other carcinogenic changes in the DMH group, which are distinctly absent in the etoricoxib-treated group. COX-2 was also seen to be highly expressed following DMH treatment. The DMH treatment caused very few apoptotic cells, as determined by the TUNEL assay of the colonic mucosa in paraffin sections whose number greatly increased following etoricoxib treatment. Because all these changes were clearly reversed by etoricoxib in DMH-treated animals, and the use of etoricoxib alone did not produce a neoplastic effect per se, it appears that etoricoxib, a selective COX-2 inhibitor, might be a safe and potentially chemopreventive agent in colon cancer.
Online Load Balancing for Energy-Aware Anycast Routing (2006)

Anycast routing offers a flexible paradigm for resource constrained, ad hoc sensor networks, where sensors can route data to any available server. The selection policy of servers in an anycast scenario could assist in keeping the network operating quiescently for a required time frame. This paper proposes a novel load balancing model to make anycast routing decisions based on route efficiency, and remaining life-times of the servers. The model makes use of the historical load and channel capacity profiles to accurately estimate the remaining life of each server. The results show that the proposed technique achieves effective reconfiguration performance to meet the network time-to-live requirement and also maintains better load-balance with anycast routing protocol
Expression and functional role of urokinase‐type plasminogen activator receptor in normal and acute leukaemic cells (1998)

Urokinase-type plasminogen activator receptor (UPA-R-CD87) is a GPI-anchored membrane protein which promotes the generation of plasmin on the surface of many cell types, probably facilitating cellular extravasation and tissue invasion. A flow cytometric quantitative analysis of expression levels for UPA-R was performed on fresh blast cells from patients with acute myeloid leukaemia (AML, n = 74), acute lymphoblastic leukaemia (ALL, n = 24), and biphenotypic leukaemia (BAL, n = 3) using two CD87 monoclonal antibodies (McAbs) (3B10 and VIM5). Peripheral blood and bone marrow (BM) cells from 15 healthy adults served as controls. Using 3B10 McAb, UPA-R was expressed (>99%) by blood monocytes, neutrophils, and BM myelomonocytic precursors in controls, whereas resting T and B lymphocytes, and CD34+ cells were UPA-R negative. We also attempted to clarify whether UPA-R has a role in mediating neutrophil functions. Oriented locomotion induced by different chemotaxins and lysozyme release by granules stimulated with fMLP or PMA were significantly decreased when UPA-R was neutralized by CD87 McAb. In contrast, the anti-UPA-R McAb had no effect on superoxide anion generation of normal neutrophils. Blasts from AML showed a heterogenous pattern of expression for the UPA-R McAbs, with reactivity strictly dependent on FAB subtype. The highest UPA-R expression was seen in the M5 group: all patients tested (n = 20) showed strong positivity for the UPA-R McAb whereas only 12% (3/24) of ALL patients were CD87 positive, and 2/3 of BAL patients showed a dim expression for CD87. The number of receptors expressed by blast cells in 6/74 (8.1%) AML patients was higher than those of normal samples: in addition, since co-expression of UPA-R and CD34 was not found in normal haemopoietic cells, it may be postulated that CD87 can be used alone (when overexpressed) or in combination with CD34 for the detection of minimal residual disease. Results also indicated that patients with UPA-receptors >12 x 10(3) ABC/cell, irrespective of FAB subtype, had a greater tendency for cutaneous and tissue infiltration and a higher frequency of chromosome abnormalities, thus suggesting the concept that cellular UPA-R content positively correlates with the invasive potential of AML cells. The combination of higher UPA-R positivity, abnormalities of chromosome 11, and M5 FAB morphology may identify a peculiar subset of AML, characterized by a more aggressive clinical course.
Cross-Talk Between IL-1 and IL-6 Signaling Pathways in Rheumatoid Arthritis Synovial Fibroblasts (2001)

The balance between pro- and anti-inflammatory cytokines plays an important role in determining the severity of inflammation in rheumatoid arthritis (RA). Antagonism between opposing cytokines at the level of signal transduction plays an important role in many other systems. We have begun to explore the possible contribution of signal transduction cross-talk to cytokine balance in RA by examining the effects of IL-1, a proinflammatory cytokine, on the signaling and action of IL-6, a pleiotropic cytokine that has both pro- and anti-inflammatory actions, in RA synovial fibroblasts. Pretreatment with IL-1 suppressed Janus kinase-STAT signaling by IL-6, modified patterns of gene activation, and blocked IL-6 induction of tissue inhibitor of metalloproteases 1 expression. These results suggest that proinflammatory cytokines may contribute to pathogenesis by modulating or blocking signal transduction by pleiotropic or anti-inflammatory cytokines. The mechanism of inhibition did not require de novo gene activation and did not depend upon tyrosine phosphatase activity, but, instead, was dependent on the p38 stress kinase. These results identify a molecular basis for IL-1 and IL-6 cross-talk in RA synoviocytes and suggest that, in addition to levels of cytokine expression, modulation of signal transduction also plays a role in regulating cytokine balance in RA.
Fused polycyclic aromatics incorporating boron in the core: fundamentals and applications (2015)

The incorporation of boron into the core structure of fused polycyclic aromatics generates compounds with highly attractive properties that have recently received significant attention. Embedding boron into the backbone of ladder or 2D poly aromatic hydrocarbons is an underexplored approach to modulate optoelectronic properties, with tricoordinate boron representing a novel acceptor moiety for organic optoelectronic applications. Furthermore, the incorporation of boron into polycyclics containing other heteroatoms (e.g., chalcogens or pnictogens) leads to more extensive structural diversity and considerable ability to modify the frontier orbital energies and character, often in a controlled manner, to fine tune material properties for specific applications. This feature article summarizes the recent key developments in this field.
Spatial Analysis of Weather Crash Patterns (2008)

Spatial statistical techniques can be an effective tool for analyzing patterns and autocorrelation in crash data, especially weather-related crashes. Since weather is a geographic phenomenon, it tends to show distinct geographic patterns affecting certain locations more than others. Accordingly, “weather-related” crashes may also display similar distinct patterns or clustering. The objective of this research was to use spatial statistical techniques to identify significant patterns of weather-related crashes. Weather-related crashes, defined as those crashes which occurred in adverse weather conditions, were analyzed using the Getis-Ord Gi*(d) statistic. The statistic reveals spatial patterns for weather-related crashes which are clustered at different locations depending upon weather conditions (snow, rain, and fog). The results also show geographic areas (counties) of statistically significant high and low relative crash rates for each weather condition. Furthermore, the resulting patterns of crashes were validated by comparing counties of high and low crash rates with areas of varying weather data. The establishment of this relationship between weather and crashes is imperative in identifying the variables contributing to these crash types and the implementation of effective countermeasures for road weather safety audit purposes.
Trends in matrix acidizing (1992)

The preferred technique for removing near-wellbore damage and stimulating high-permeability formations, matrix acidizing is going through another renaissance, thanks to computer-aided systems helping job design, job execution and postjob analysis. A review is given of matrix acidizing from A to Z, passing through chemistry, horizontal well applications and what the computer-aided techniques can offer. 24 figs., 28 refs.
Sensory channel threats to Cyber Physical Systems: A wake-up call (2014)

Cyber-Physical Systems (CPS) is a relatively novel computing paradigm where there is a tight integration of communications, computation, and the physical environment. An important component of the CPS devices is the sensors they use to interact with each other and the physical world around them. With CPS applications, engineers monitor the structural health of highways and bridges, farmers check the health of their crops, and ecologists observe wildlife in their natural habitat. Nonetheless, current security models consider protecting only networking components of the CPS devices utilizing traditional security mechanisms (e.g., an intrusion detection system for the data that traverse the network protocol stacks). The protection mechanisms are not sufficient to protect CPS devices from threats emanating from sensory channels. Using sensory channels (e.g., light, temperature, infrared), an adversary can successfully attack systems. Specifically, the adversary can (1) trigger existing malware, (2) transfer malware, or (3) combine malicious use of different sensory channels to increase the impact of the attack on CPS devices. In this work, we focus on these novel sensory channel threats to CPS devices and applications. We first note how sensory channel threats are an emerging area for the CPS world. Then, we analyze the performance various sensory channel threats. Moreover, using an iRobot Create as our CPS platform, we exploit simple vulnerable programs on iRobot through its infrared channel. Finally, we introduce the design of a novel sensory channel aware intrusion detection system as a protection mechanism against the sensory channel threats for CPS devices.
Fast nearest-neighbor search based on Voronoi projections and its application to vector quantization encoding (1999)

In this work, we consider two fast nearest-neighbor search methods based on the projections of Voronoi regions, namely, the box-search method and the cell-partition search method. We provide their comprehensive study in the contest of vector quantization encoding. We show that the use of principal component transformation reduces the complexity of Voronoi-projection based search significantly for data with high degree of correlation across their components.
Cluster Touch (2019)

We present Cluster Touch, a combined user-independent and user-specific touch offset model that improves the accuracy of touch input on smartphones for people with motor impairments, and for people experiencing situational impairments while walking. Cluster Touch combines touch examples from multiple users to create a shared user-independent touch model, which is then updated with touch examples provided by an individual user to make it user-specific. Owing to this combination, Cluster Touch allows people to quickly improve the accuracy of their smartphones by providing only 20 touch examples. In a user study with 12 people with motor impairments and 12 people without motor impairments, but who were walking, Cluster Touch improved touch accuracy by 14.65% for the former group and 6.81% for the latter group over the native touch sensor. Furthermore, in an offline analysis of existing mobile interfaces, Cluster Touch improved touch accuracy by 8.21% and 4.84% over the native touch sensor for the two user groups, respectively.
Distributed scheduling to support mass customization in the shoe industry (2004)

Abstract The European shoe industry has experienced significant challenges in the last 20 years, mainly due to the pressures of modern global markets in which the industry has to compete with competitors from low labour cost countries in Asia and the Far East. A new trend is now forecast concerning the mass customization of shoes, where customers choose and order customized shoes from a range of predefined materials and designs. This is to be achieved through the 'shoe shop of the future' with combined capabilities of obtaining 3D models of customer's feet together with the exciting developments offered through the latest advancement in e-commerce. However, such a novel approach for the customization of shoe design and production will have a significant influence on the batch sizes and expected lead times, and will reduce the average batch size of shoe production from 500–1000 pairs to about 10–20 pairs per batch. Consequently, customized shoes will result in an enormous increase in the number of batches, leading to an increase in the complexity of planning, scheduling and tracking of orders both across the supply chain and internally within various production departments of a shoe factory. This research proposes a distributed scheduling approach to provide the required autonomy in decision making and flexibility in job sequencing at departmental level to deal with the complexity of planning a large number of small batch production orders. Acknowledgements The work reported in this paper has been carried out within a European-based research programme, namely CICLOP: Computer Integrated Closing Operations (EU Framework 5 – CRAF-1999-71422). The authors would like to acknowledge the collaboration of PREACTOR International Ltd and the supporting work of other participants in the CICLOP project.
Increased Vertical Transmission of Human Immunodeficiency Virus from Hepatitis C Virus‐Coinfected Mothers (1997)

To determine if hepatitis C virus (HCV) infection affects vertical transmission of human immunodeficiency virus (HIV), 487 HIV-infected pregnant women in the prospective, multicenter, Women and Infants Transmission Study had HCV antibody (anti-HCV by second-generation ELISA) and HCV RNA (by quantitative polymerase chain reaction) measured in peripartum maternal plasma; 161 (33%) were anti-HCV-positive. HIV vertical transmission occurred from 42 HCV-infected mothers (26.1%) versus 53 HCV-uninfected mothers (16.3%; odds radio [OR], 1.82; P = .01). In a logistic regression model that included maternal drug use, a potential confounder, HCV infection was marginally associated with perinatal HIV transmission (OR, 1.64; P = .05), whereas drug use was not. Women who transmitted HIV had higher levels of HCV RNA (median, 721,254 copies/mL) than those who did not (337,561 copies/mL; P = .01). Maternal HCV infection is associated with increased HIV vertical transmission. Further studies are needed to ascertain if HCV directly affects perinatal HIV transmission or is a marker for another factor, such as maternal drug use.
MECHANISM OF BONE FORMATION WITH GENE TRANSFER OF THE CDNA ENCODING FOR THE INTRACELLULAR PROTEIN LMP-1 (2003)

The osteoinductive properties of LMP-1 involve synthesis of several BMPs and the recruitment of host cells that differentiate and participate in direct membranous bone formation.
Zirconium meso-octaethylporphyrinogen as a carrier for sodium hydride in toluene: zirconium-sodium bimetallic hydride and alkyls (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTZirconium meso-octaethylporphyrinogen as a carrier for sodium hydride in toluene: zirconium-sodium bimetallic hydride and alkylsDenis Jacoby, Carlo Floriani, Angiola Chiesi-Villa, and Corrado RizzoliCite this: J. Am. Chem. Soc. 1993, 115, 9, 3595–3602Publication Date (Print):May 1, 1993Publication History Published online1 May 2002Published inissue 1 May 1993https://pubs.acs.org/doi/10.1021/ja00062a024https://doi.org/10.1021/ja00062a024research-articleACS PublicationsRequest reuse permissionsArticle Views544Altmetric-Citations52LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (4)»Supporting Information Supporting Information Get e-Alerts
The potential of a patient-centred video to support medication adherence in kidney transplantation: A three-phase sequential intervention research (2017)

The potential of a patient-centred video to support medication adherence in kidney transplantation: A threephase sequential intervention research
Distinguishing freehand drawing recognition for biometricauthentication on Android-powered mobile devices (2012)

The goal of this work is to develop a recognition algorithm for biometric authentication using a freehand drawing. There are similar studies about signature verification or keystroke typing[1] but there are not any work about freehand drawing surprisingly.
To achieve this goal we find, analyzed and selected 6 different biometric feature that are sufficient to distinguish two different people drawing the same sketch. First the enrollment and then the recognition algorithms are intentionally not difficult or complex to understand and implement.
The whole work has been developed for and tested on Android-powered mobile devices which has assured an easy-to-use interface and usage and a touchscreen technology ready-to-use.
In chapter 1 we introduce the complete work done and we give an overview about bio- metrics and the state of the art.
In chapter 2 we give some information about the Android platform and Android Development Tools.
In chapter 3 we analyze the selected features explaining the recognition algorithm in detail. 
In chapter 4 we explain our choices, we present and comment the test results.
In appendix A we write a user manual to make usage easy
Toward Predictive Fault Tolerance in a Core-Router System: Anomaly Detection Using Correlation-Based Time-Series Analysis (2017)

Fault tolerance is used in communication systems to ensure high reliability and rapid error recovery. The effectiveness of most proactive fault-tolerant mechanism depends on whether anomalies can be accurately detected before a failure occurs. However, traditional anomaly detection techniques fail to detect “outliers” when the monitored data involves temporal measurements and exhibits significantly different statistical characteristics for its constituent features. We describe the design of an anomaly detector that monitors the time-series data of a complex core router system. Anomaly detection techniques are compared in terms of their effectiveness for detecting different types of anomalies. A feature-categorizing-based hybrid method is proposed to overcome the difficulty of detecting anomalies in features with different statistical characteristics. Furthermore, a correlation analyzer is implemented to remove irrelevant and redundant features. Three types of synthetic anomalies, generated using a small amount of real data for a commercial telecom system, are used to validate the proposed anomaly detector.