gebhart/patrepeval huggingface dataset:
Geometry-Aware Instance Segmentation with Disparity Maps (2020)

Most previous works of outdoor instance segmentation for images only use color information. We explore a novel direction of sensor fusion to exploit stereo cameras. Geometric information from disparities helps separate overlapping objects of the same or different classes. Moreover, geometric information penalizes region proposals with unlikely 3D shapes thus suppressing false positive detections. Mask regression is based on 2D, 2.5D, and 3D ROI using the pseudo-lidar and image-based representations. These mask predictions are fused by a mask scoring process. However, public datasets only adopt stereo systems with shorter baseline and focal legnth, which limit measuring ranges of stereo cameras. We collect and utilize High-Quality Driving Stereo (HQDS) dataset, using much longer baseline and focal length with higher resolution. Our performance attains state of the art. Please refer to our project page. The full paper is available here.
Basic Theory and Design Method of Variable Shaft Angle Line Gear Mechanism (2021)

In this paper, a novel line gear mechanism is proposed; it is called the variable shaft angle line gear mechanism (VSALGM). VSALGM has two rotational degrees of freedom, one is the rotation of the two gears with a constant transmission ratio, and the other is the relative swing of the two gears shafts. First, a novel contact model of VSALGM composed of one driven contact curve and one driving line teeth working surface (DLTWS) was proposed. With the concept, the basic design equations for VSALGM were derived on the basis of the space curve meshing theory of line gear. Moreover, the design criterion of pressure angle for VSALGM was analysed and proposed on the basis of the contact model. A basic design method for VSALGM was thus developed. A design example was given, and prototypes were manufactured using three-dimensional (3D) printing. Kinematic experiments and gear contact spot testing were carried out on a self-made kinematic test rig by the prototypes. The results show that the VSALGM designed in this paper can achieve a continuous, smooth and stable meshing transmission while the shaft angle is continuously changed within its setting range.
Functional Properties of Human b2-Adrenergic Receptor Polymorphisms (1995)

The same b2-adrenergic receptor is not expressed throughout the human population;there are at least six different forms of the receptor due to genetic polymorphisms within the coding block of the receptor gene. Site-directed mutagenesis and recombinant expression have shown that some of these variants have distinct pharmacological and biochemical phenotypes.
Linear B-Cell Epitope Mapping Using Enzyme-Linked Immunosorbent Assay for Libraries of Overlapping Synthetic Peptides (2009)

The aim of this chapter is to provide a strategy for mapping linear antibody epitopes of protein antigens in order to discover candidates for vaccines or diagnostic tests. A set of overlapping peptides was designed and synthesised based upon a known amino acid sequence of the target protein, virulence-associated protein A (VapA) of the bacterium Rhodococcus equi, an important pulmonary pathogen in foals.The peptides were biotinylated and used in an ELISA to screen immune sera from foals. These biotinylated peptides were coated directly onto micro titre plates that had been pre-coated with NeutrAvidin. A linear B-cell epitope was identified by a universal recognition of sera to the synthetic peptides which corresponds to a particular fragment of the VapA protein.
On the Marginalization of Polarizing Kernels (2018)

In this paper, we analyze the decoding complexity of polarizing kernels of size larger than p = 2, proposing a general procedure which can be used to marginalize kernels of any size. We use this method to evaluate the decoding equations for optimal binary kernels up to size p = 8. Finally, we experimentally show that, even if T <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> and T <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">8</sub> share the same polarization exponent, their performance may vary under list decoding, making large kernels of interest for long polar codes.
Voltage-controlled optical/RF phase shifter (1985)

A new fiber-optic device designed to steer the radiation beam of a phased-array antenna has been demonstrated. A radiofrequency (RF) signal at 125 MHz is generated via photomixing at the output of a single-mode fiber-optic interferometer. The phase of the electrical signal is shifted over several cycles in direct proportion to a voltage applied to an optical controller. The controller consists of a Pockels-type optical phase modulator located in one arm of the heterodyne interferometer. Rapid changes in RF phase are feasible. A miniature low-voltage version of the device, based upon integrated optics, is proposed.
A noise-tolerant matchline scheme with XOR-based conditional keeper for energy-efficient TCAM (2006)

A novel AND-type match-line scheme with XOR-based conditional keeper for ternary content-addressable memory (TCAM) are presented in this paper. The XOR-based conditional keeper is turned off at some critical moments to reduce the search time and power consumption. High fan-in AND-type match-line schemes are used to demonstrate the effectiveness of the XOR-based conditional keeper in the presence of noise sources. 37.8% search time reduction and 15.6% power saving are achieved by using the proposed TCAM architecture. Based on TSMC 0.13 /spl mu/m CMOS technology at 1.2 V supply voltage, a 256 words /spl times/ 128 bits ternary CAM is designed. The simulation results show that the search time of proposed TCAM architecture is 1.17 ns and energy metric of proposed TCAM architecture is 0.752 fJ/search.
Speech recognition system (1992)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Toyohisa Kaneko, Osaaki Watanuki; Speech recognition system. J. Acoust. Soc. Am. 1 April 1992; 91 (4): 2305–2306. https://doi.org/10.1121/1.403610 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAcoustical Society of AmericaThe Journal of the Acoustical Society of America Search Advanced Search |Citation Search
Abstract B016: Allogenic CAR T-cells for adoptive immunotherapy (2016)

Abstract Chimeric antigen receptor (CAR)-redirected T-cells have given rise to long-term durable remissions and remarkable objective response rates in patients with refractory leukemia, raising hopes that a wider application of CAR technology may lead to a new paradigm in cancer treatment. A limitation of the current autologous approach is that CAR T-cells must be manufactured on a “per patient basis”. We have developed a standardized platform for manufacturing T-cells from third-party healthy donors to generate allogeneic “off-the-shelf” engineered CAR+ T-cell–based frozen products. This platform utilizes Transcription Activator-Like Effector Nuclease (TALEN) gene editing technology to inactivate the TCRα constant (TRAC) gene, eliminating the potential for T-cells bearing alloreactive TCR's to mediate Graft versus Host Disease (GvHD). We have previously demonstrated that editing of the TRAC gene can be achieved at high frequencies, obtaining up to 80% of TCRβα negative cells. This allows us to efficiently produce TCR-deficient T-cells that have been shown to no longer mediate alloreactivity in a xeno-GvHD mouse model. We have adapted this allogeneic platform to the production of T cells targeting CD123, the transmembrane alpha chain of the interleukin-3 receptor, which is expressed in tumor cells of patients with Acute Myeloid Leukemia as well as CS1 a glycoprotein highly expressed on tumor cells of patients with multiple myeloma. We will present both in vitro and in vivo data demonstrating specific anti-tumor activity of engineered CAR T cells against cell lines expressing the targeted antigen. Citation Format: Roman Galetto, Celine Lebuhotel, Isabelle Chion-Sotinel, Patricia Francon, Agnes Gouble, Julianne Smith. Allogenic CAR T-cells for adoptive immunotherapy. [abstract]. In: Proceedings of the CRI-CIMT-EATI-AACR Inaugural International Cancer Immunotherapy Conference: Translating Science into Survival; September 16-19, 2015; New York, NY. Philadelphia (PA): AACR; Cancer Immunol Res 2016;4(1 Suppl):Abstract nr B016.
Symbol repetition and power re-allocation scheme for orthogonal code hopping multiplexing systems (2005)

We propose a symbol repetition and power re-allocation scheme to reduce a collision effect in orthogonal code hopping multiplexing (OCHM) systems. Each mapped symbol is repeated N times and an OCHM scheme is applied for downlink transmission. Through repetitions, the perforation effect is decentralized among the repeated symbols and the full perforation probability is significantly reduced. The transmit power is re-allocated among the repeated symbols to protect the symbols regardless of the number of perforations in the repeated symbols. Simulation results show that the proposed scheme saves the required energy by 4 dB in the independent Rayleigh fading channels for a frame error rate (FER) value of 1% when the perforation probability is 0.25.
Detecting Pathogen-Associated RNA via <i>Piecewise Isothermal Testing</i> achieving Sample-to-Result Integration (2021)

Abstract We report a novel piece-wise isothermal nucleic acid test ( PINAT ) for diagnosing pathogen-associated RNA that embeds an exclusive DNA-mediated specific probing reaction with the backbone of an isothermal reverse-transcription cum amplification protocol as a unified single-step procedure. This single step sample-to-result test method has been seamlessly integrated in an inexpensive, scalable, pre-programmable and portable instrument, resulting in a generic platform technology for detecting nucleic acid from a wide variety of pathogens. The test exhibited high sensitivity and specificity of detection when assessed using 200 double-blind patient samples for detecting SARS-CoV-2 infection conducted by the Indian Council of Medical Research (ICMR), reporting a positive and negative percent agreement of 94.6% and 98% respectively. We also established its efficacy in detecting influenza-A infection, performing the diagnosis at the point of collection with uncompromised detection rigor. The envisaged trade-off between advanced laboratory-based procedures with the elegance of common rapid tests renders the innovation to be ideal for deployment in resource-limited settings towards catering the needs of the underserved.
A High-Performance Solution-Processable Hybrid Thermoelectric Material (2012)

Thermoelectrics have the potential to become an alternative power source for distributed electrical generation as they could provide co-generation anywhere thermal gradients exist. More recent material and manufacturing advances have further suggested that thermoelectrics could independently generate primary power [1]. However, due to cost, manufacturability, abundance, and material performance, the full potential of thermoelectrics has yet to be realized. In the last decade, thermoelectric material improvements have largely been realized by diminishing thermal conductivities via nanostructuring without sacrificing performance in electrical transport [2]. An alternative approach is to decouple and optimize the electrical conductivity and thermopower using the unique properties of organic-inorganic interfaces [3]. One method to do this could leverage the electrical properties of a conducting polymer in combination with the thermoelectric proprieties of an inorganic semiconductor in such a way that the interaction between these materials breaks mixture theory. Furthermore, it is expected that the thermal conductivity of this hybrid material would be low due to the inherent vibration mode mismatch between polymers and inorganics. Previously, we have developed a method for producing a solution-processable thermoelectric material suitable for thin film applications using a hybrid polymer-inorganic systems consisting of crystalline tellurium nanowires coated in a thin layer of a conducting polymer (i.e., PEDOT:PSS) [4]. The interfacial properties could be realized in bulk and films demonstrate enhanced transport properties beyond those of either component. More recently, we have been able to significantly improve the thermoelectric properties of these materials by morphological and chemical modifications. Here, we present our methodology and experimental transport properties of this new material where the thermal conductivity, electrical conductivity, and thermopower predictably vary as a function of composition, size, and the structural conformation caused by the solvent. The mechanism for these improvements is currently under investigation, but experimental results suggest that transport is dominated by interfacial phenomena. Furthermore, experiments suggest that both the electrical conductivity and thermopower can be independently increased without appreciably increasing the thermal conductivity. These improvements, in concert with the solution processable nature of this material, make it ideal for new thermoelectric applications.
Multi‐arm star polyisobutylenes: 2. The effect of synthesis conditions on the structure of star PIBs (1995)

Abstract Multi‐arm star polyisobutylenes ( * ‐(PIB) n ) have been prepared by the “arm‐first” method. This synthesis was accomplished by adding various linking agents (“core builders”) such as p ‐ and m ‐divinylbenzene (DVB) and p ‐ and m ‐diisopropenylbenzene (DIB) to living PIB® charges and thus obtaining a crosslinked aromatic core holding together a corona of well‐defined arms. The products were characterized in terms of overall arm/core composition, molecular weight, and molecular weight distribution (M̄ w /M n ). The effect of reaction conditions (time, [linking agent]/[PIB], arm molecular weight) on the kinetics of the star formation and star structure were investigated. The multi‐arm star nature of * ‐(PIB) n s was proven directly by determining the molecular weight (by light scattering) of the intact products, selectively destroying the aromatic polyDVB (or polyDIB) core (“core‐destruction”), and finally determining the molecular weight of the surviving aliphatic PIB arms. The synthetic strategy, overall kinetics, and observations during the preparation of star‐PIBs were discussed. Among the critical parameters that determine product structures are the rate of crossover PIB ⊕ + DVB (or DIB) → PIB‐DVB ⊕ (or PIB‐DIB ⊕ ), the concentration of the linking agent DVB (or DIB), and the molecular weight of the PIB arm. Evidence for the formation of higher order stars (“secondary”, etc.) by star‐star‐ coupling has been presented.
Influences of myogenin genotypes on birth weight, growth rate, carcass weight, backfat thickness, and lean weight of pigs. (1999)

Lean weight is related to muscle fiber number. Muscle fiber formation (myogenesis) occurs only during embryonic development when it is under the control of the MyoD gene family consisting of myogenin, MyoD1, myf-5, and myf-6. Myogenin has a central position within the MyoD gene family because myogenin expression abrogates myoblast proliferation potential and regulates the differentiation of single nucleated myoblasts into multinucleated myofibers. Thus, myogenin genotype could be related to variation in the number of muscle fibers formed, leading to variation in muscle mass and, thus, lean weight. A polymorphism at the porcine myogenin locus was associated with birth weight, growth rate, lean weight at 200 d, and backfat thickness. Yorkshire pigs from two commercial lines were genotyped, and crosses between heterozygous pigs and heterozygous and homozygous pigs were made. Resulting litters were genotyped, and phenotypic data were collected. Significant differences were found between the two homozygous myogenin genotypes for birth weight, growth rate, and lean weight, but not for backfat thickness. Variation at the myogenin locus explained 4% of the total phenotypic variation in birth weight, growth rate, and carcass weight, and 5.8% of the total variation in lean weight. We conclude that myogenin genotype influences porcine growth rate and muscle mass.
Non-Cannabinoid Metabolites of Cannabis sativa with Therapeutic Potential (2020)

The Cannabis plant (Cannabis sativa L.) produces an estimated 545 chemical compounds of different biogenetic classes. In addition to economic value, many of these phytochemicals have medicinal and physiological activity. The plant is most popularly known for its two most prominent and most studied secondary metabolites— Δ9-Tetrahydrocannabinol (Δ9-THC) and Cannabidiol (CBD). Both Δ9-THC and CBD have a wide therapeutic window across many ailments and form part of a class of secondary metabolites called cannabinoids—of which approximately over 104 exist. This review will focus on non-cannabinoid metabolites of Cannabis sativa that also have therapeutic potential, some of which share medicinal properties similar to those of cannabinoids. The most notable of these non-cannabinoid phytochemicals are flavonoids and terpenes. We will also discuss future directions in cannabis research and development of cannabis-based pharmaceuticals. Caflanone, a flavonoid molecule with selective activity against the human viruses including the coronavirus SARS-COV2, and certain cancers, is one of the most promising non-cannabinoid molecules that is being advanced into clinical trials. As validated by thousands of years of the use of cannabis for medicinal purposes, vast anecdotal evidence abounds on the medicinal benefits of the plant. These benefits are attributed to the many phytochemicals in this plant, including non-cannabinoids. The most promising non-cannabinoids with potential to alleviate global disease burdens are discussed.
Inhibitory oligonucleotide (IN-ODN) structure-function relationships: species and backbone differences (131.19) (2007)

Abstract The recognition of CpG motifs in bacterial DNA by Toll-like Receptor (TLR9) is a key function of the innate immune system, announcing the presence of an infection. We have previously developed synthetic oligonucleotide (ODN) inhibitory of TLR9 function with phosphorothioate (S) backbones conforming to the sequence n CC n not C not C nn GGG nnnn where n is any base. Here we show that these sequence requirements generate IN-ODN when the backbone is phosphodiester (O) also. In general, whereas stimulatory O-ODN are 2 logs less potent than their S-backbone congeners IN-ODN are 3 logs less potent. Changes in the critical bases diminish activity with either backbone; however, when the backbone is S, such changes diminish activity of stimulators much less, and inhibitors much more, than if the backbone is O. Certain end truncations enhance activity and even the minimal sequence CCTGGAGGG retains substantial inhibitory activity. Human-mouse relative activity comparisons tend to be similar between critical base variants, but may differ substantially between end truncation variants. HEK cells transfected with mouse or human TLR9 and an NFkB binding luciferase promoter respond to much lower concentrations of IN-ODN than do primary cells of either species. The neutral sequences with S backbones developed for mouse cells are also neutral with O backbones and with human cells. Supported by AI04737405 from NIH
Photopolymerization upon LEDs: new photoinitiating systems and strategies (2015)

The use of LEDs as novel and efficient light sources for the photopolymerization of various monomers (acylate, epoxy), interpenetrating polymer networks and thiols–ene, leads to the development of novel photoinitiating systems adapted for the LED emission.
Comparison of stimulated and spontaneous laser-radar methods for the remote sensing of ocean physical properties (1990)

The physical properties of ocean water, in the top few ten meters, are of great interest in the scientific, engineering, and general oceanographic communities. Subsurface profiles of temperature, salinity, and sound speed measured by laser radar in real time on a synoptic basis over a wide area from an airborne platform would provide valuable information complementary to the data that is now readily available. The laser-radar technique specifically applicable to ocean sensing uses spectroscopic analysis of the inelastic backscattered optical signal. Two methods have received considerable attention for remote sensing and both have been demonstrated in field experiments. These are spontaneous Raman1 and spontaneous Brillouin2 scattering. A discussion of these two processes and a comparison of their properties that are useful for remote sensing was presented3 at SPIE Ocean Optics IX. This paper compares ocean remote sensing using stimulated Brillouin scattering (SBS) and stimulated Raman scattering (SRS) processes with better known spontaneous methods. The results of laboratory measurements of temperature using SBS and some preliminary results of SRS are presented with extensions to performance estimates of potential field systems.
Self-healing fibre grating sensor system using tunable multiport fibre laser scheme for intensity and wavelength division multiplexing (2002)

A fibre grating sensor system using a tunable multiport fibre laser scheme for intensity and wavelength division multiplexing is proposed. The power ratio (1:2:3) between each output port is used to address the sensing information. The network survivability is also considered. This fibre grating sensor system can enhance the sensing capacity and reliability.
Prenatal Screening for Down's Syndrome with Use of Maternal Serum Markers (1992)

Measuring serum alpha-fetoprotein, chorionic gonadotropin, and estriol is more effective in screening for fetal Down's syndrome than measuring maternal serum alpha-fetoprotein alone. Such an expanded protocol can readily be incorporated into existing prenatal screening programs.