gebhart/patrepeval huggingface dataset:
Example-based hair geometry synthesis (2009)

We present an example-based approach to hair modeling because creating hairstyles either manually or through image-based acquisition is a costly and time-consuming process. We introduce a hierarchical hair synthesis framework that views a hairstyle both as a 3D vector field and a 2D arrangement of hair strands on the scalp. Since hair forms wisps, a hierarchical hair clustering algorithm has been developed for detecting wisps in example hairstyles. The coarsest level of the output hairstyle is synthesized using traditional 2D texture synthesis techniques. Synthesizing finer levels of the hierarchy is based on cluster oriented detail transfer. Finally, we compute a discrete tangent vector field from the synthesized hair at every level of the hierarchy to remove undesired inconsistencies among hair trajectories. Improved hair trajectories can be extracted from the vector field. Based on our automatic hair synthesis method, we have also developed simple user-controlled synthesis and editing techniques including feature-preserving combing as well as detail transfer between different hairstyles.
Library book circulation and the beta-binomial distribution (1987)

Library book circulation does not appear to be a Poisson process. It is proposed that a binomial process is more logical and that the mixture distribution for individual book popularities is a continuous beta distribution. Three examples are given which indicate the superiority of the beta—over the negative binomial distribution. A bivariate beta-binomial should be of help to the librarian in predicting future book circulations. © 1987 John Wiley & Sons, Inc.
Comparison of two bioelectrical impedance analysis models for total body water measurement in children (1992)

We compared two bioelectrical impedance analysis models, the right-sided tetrapolar method and an experimental cylindrical method, to total body water (TBW) determined by isotopic dilution in 37 prepubertal children aged 5-9 years, who were divided into development and cross-validation groups. Despite its theoretical advantage, no improvement in predicted TBW was seen with the experimental method. The best predictive equation, using the tetrapolar method, was TBW (kg) = 1.84 + 0.45 (height square/resistance) +0.11(weight); r2 = 0.98; SEE = 0.62 kg.
Dependence of the I-V curve of a metal insulator semiconductor switch on insulator thickness-an experimental and theoretical investigation (1998)

Although the metal insulator semiconductor switch (Al/SiO/sub 2//n-Si/p-Si) has been investigated for quite some time, there has been no systematic report on the influence of the oxide thickness on the current-voltage (I-V) curve. We fabricated four types of metal insulator semiconductor switches where the only intentional difference was the thickness of the oxide. We observed, both experimentally and by simulation, that the I-V curves of these devices are very sensitive to the oxide thickness. While the simulated curves only agree with the measured ones in certain trends, the simulation provides some insight to the operation of the device. The onset of the negative resistance region in the curve is so sensitive to the electron and hole tunneling currents that the these devices could be used to characterize ultrathin oxides. Extremely high current densities (10/sup 3/ A/cm/sup 2/) have been driven through the ultrathin oxides without significantly changing the device characteristics. We believe this is the highest, steady-state, current density through an oxide reported to date.
Inactivation of Clostridium sporogenes in Clover Honey by Pulsed UV-light Treatment (2003)

Honey has naturally low levels of microorganisms due to its low water content and highconcentration of sugars. However, it has been known to contain the spores of yeast, mold, andbacteria resulting in growth and spoilage of the product. Clostridium botulinum, is associated withhoney and is known to cause a disease called botulism. Heat pasteurization, pressure treatment,and irradiation have all been studied as methods of killing the spores, but have been found lacking.Pulsed Ultraviolet (UV)-Light Sterilization is a novel processing method used for microbialinactivation. For the experimentation, spores of C. sporogenes were prepared from cooked meatmedium cultures grown in an anaerobic jar for 7 days at 37oC. Honey was inoculated with 0.1 ml ofC. sporogenes spore suspension per 20 g honey, and mixed well. Pulsed light was applied to theinoculated honey using the SteriPulse XL 3000 Pulsed Light Sterilization System provided byNASA Commercial Food Technology Center. The following parameters were analyzed: 1) thenumber of pulses 2) the distance between the food product and lamp 3) depth of honey. Treatedand untreated (control) honey was analyzed for C. sporogenes.
Optimising broadband tunable wavelength conversion in fibre optical parametric amplifiers (2004)

We present device parameters for low ripple maximum gain bandwidth in tunable optical parametric wavelength converters. Expressions for conversion bandwidth are given for typical fibre dispersion parameters.
Assembly sequencing with toleranced parts (1995)

The goal of assembly sequencing is to plan a feasible series of operations to construct a product from its individual parts. Previous research has investigated assembly sequencing under the assumption that parts have nominal geometry. This paper considers the case where parts have tolerance geometry. Its main contribution is an efficient procedure that decides if a product admits an assembly sequence with infinite translations that is feasible for all possible instances of the components within the specified tolerances.
Metabolism of Acrylate Esters in Rat Tissue Homogenates (1981)

Metabolism of Acrylate Esters in Rat Tissue Homogenates. R.R. Miller, J.A. Ayres, L.W. Rampy and M.J. McKenna. (1981). Fundam. Appl. Toxicol. 1:410–414. Methyl, ethyl and butyl acrylate were hydrolyzed to acrylic acid in rat liver, kidney and lung homogenates. The rates of hydrolysis of the various esters in these in vitro studies were comparable; hydrolysis rates were approximately 20 times higher in liver homogenates than in kidney or lung homogenates. The esters also disappeared rapidly when added to blood in vitro. However, the disappearance in blood was not associated with the appearance of acrylic acid. Ethyl acrylate was found to react spontaneously with GSH in vitro and this reaction was catalyzed greatly by enzymes in 100 000 x g liver supernatant. Acrylic acid did not react with GSH in vitro. Ethyl acrylate, but not acrylic acid, depletes non-protein sulfhydryls when added to blood in vitro. Thus, the disappearance of acrylate esters in blood in vitro could be due at least in part to binding with non-protein sulfhydryls in red blood cells rather than to hydrolysis.
Novel biomarkers predict liver fibrosis in hepatitis C patients: alpha 2 macroglobulin, vitamin D binding protein and apolipoprotein AI (2010)

This study not only reveals three putative biomarkers of liver fibrosis (A2M, VDBP and ApoAI) but also proves the differential expressions of those markers in different stages of fibrosis. We expect that combination of these novel biomarkers could be applied clinically to predict the stage of liver fibrosis without the need of liver biopsy.
Software and Simulation Modeling for Real-Time Software-Intensive Systems (2004)

Successful development of large-scale complex and distributed real-time systems commonly relies on models developed separately for simulation studies and software implementation. Systems theory provides sound modeling principles to characterize structural and behavioral aspects of systems across time and space. The behavior of these models can be observed using simulation protocols that can correctly interpret time-based logical dynamics. Similarly, object-orientation theories and software architecture principles enable modeling static and dynamic behavior of systems. While models described either in system-theoretic or object-orientated languages may be used for both software design and simulation modeling, each has its own strengths and weaknesses. For example, a class of system-theoretic modeling approach called Discrete-event System Specification (DEVS) provides an appropriate basis to develop simulation models exhibiting concurrent and distributed behavior. Similarly, the Unified Modeling Language with real-time (UML-RT) constructs can be used to develop software design models that can be implemented and executed. Since software models are not suitable to be used as simulation models and simulation models may not adequately lend themselves to serve as software design blueprints, it is important to examine these approaches. We show some of the key shortcomings of these simulation and software design modeling approaches by developing some detailed specifications and implementation of a coffee machine with a focus on their treatment of logical and physical time.
Renal cisplatin chemoembolization with Angiostat, Gelfoam, and Ethiodol in the rabbit: renal platinum distributions. (1989)

Renal platinum distributions were determined in rabbits after administration of 0.4 mL of 1 mg/mL cisplatin by intravenous infusion, by injections into the left renal artery with aqueous contrast material and with lipid contrast material (Ethiodol), and by chemoembolization of the left renal artery with concurrent administration of various concentrations of two collagen carriers, Angiostat collagen for embolization and Gelfoam gelatin. Renal platinum concentration was measured in tissue homogenates at 2 1/2 hours with atomic absorption spectrometry. Target-kidney platinum levels were 5.4 and 6.9 times the contralateral-kidney levels after intraarterial infusion of aqueous and lipid contrast media, respectively. With Angiostat and Gelfoam chemoembolization, renal platinum retention and collagen concentration were linearly related (r = .87 and .81, P less than .001). Target-kidney-contralateral-kidney platinum ratios were 57:1 for 30 mg/mL Gelfoam and 220:1 for 10 mg/mL Angiostat. The difference in regional drug retention for Angiostat versus Gelfoam reflects the stable fiber integrity of Angiostat.
Gene-Enzyme Relationships of Aromatic Acid Biosynthesis in <i>Bacillus subtilis</i> (1973)

Mutants have been isolated which correspond to every step concerned with the biosynthesis of the aromatic amino acids in Bacillus subtilis. Each mutant has been characterized, and the lesion it bore was analyzed by deoxyribonucleic acid transformation and PBS-1 mediated transduction. The biochemical analysis revealed that each of the mutations appears to have affected a single enzyme, except for two groups of pleiotropic mutations. All aroF mutants (chorismic acid synthetase) lack dehydroquinic acid synthetase (aroB) activity. The gene that specifies aroB is closely linked to the gene coding for the aroF enzyme. Both genes are a part of the aro cluster. Mutants lacking chorismate mutase activity also lack d-arabino-heptulosonic acid-7-phosphate synthetase and shikimate kinase activity, presumably as a result of these three activities forming a multi-enzyme complex. Another mutant, previously undescribed, had been isolated. The affected gene codes for the tyrosine and phenylalanine aminotransferase activity. All of the mutations have been located on the B. subtilis genome except those in the genes specifying shikimate kinase activity and tyrosine-phenylalanine aminotransferase activity.
<i>Acoustics: Waves and Oscillations</i> (1991)

First Page
A novel mesh-free poly-cell Galerkin method (2009)

一个新奇数字方法被探索并且称为同样没有网孔的 poly 房间 Galerkin 方法。改进移动最少平方(MLS ) 计划被介绍，它能在标准 MLS 避免矩阵倒置并且能被用来构造拥有三角洲 Kronecher 的形状功能性质。本地支持的一种新类型被介绍与背景网孔的房间保证不可分的领域的排列，它将减少在集成困难。集中的数字研究被进行测试现在的方法的精确性。有好精确性的答案能与现在的方法被获得，这被观察。
Optical limiting behavior of nano-gold self-assembled multi-wall carbon nanotube (2005)

The optical limiting behaviors of nano-gold self-assembled multi-wall carbon nanotube (MWNT) were experimentally investigated at 532 and 1064 nm, respectively. The comparison of the limiting performances between carbon nanotube suspension, C60 solution, and carbon black suspension (CBS) was performed. The results show that the optical limiting characteristic of nano-gold self-assembled MWNT is better than those of C60 and CBS. The mechanisms of the optical limiting for the samples were discussed.
10MHz 64 Bit Error Tolerant Signature Recognition Circuit (1987)

This paper a circuit will be presented which identifies a 64 bit synchronization word in a serial incoming data stream. The signature is identified when the incoming data stream matches a previously known and stored signature. It is also possible to program the number of bit errors permissible for recognition of the signature. The circuit was fabricated in a 1.5?m CMOS technology for use in a D2MAC television decoder. The circuit operates at data rates up to 20MHz and covers an area of 1.4 × 0.1 mm2
Ulcerative Colitis and Colorectal Carcinoma: DNA-Profile, Laminin-5 ?2 Chain and Cyclin A Expression as Early Markers for Risk Assessment (2001)

(2001). Ulcerative Colitis and Colorectal Carcinoma: DNA-Profile, Laminin-5 ?2 Chain and Cyclin A Expression as Early Markers for Risk Assessment. Scandinavian Journal of Gastroenterology: Vol. 36, No. 7, pp. 751-758.
Diagnostic and prognostic role of basic fibroblast growth factor in Wilms' tumor patients. (1995)

Basic fibroblast growth factor (bFGF) is a potent angiogenic peptide implicated in the growth and metastasis of solid tumors. Elevated concentrations of bFGF have been found in the urine of patients with bladder, prostate, and renal tumors. Furthermore, urinary bFGF levels have been shown to correlate with extent of disease. In order to test the utility of urinary bFGF as a Wilms' tumor marker, we measured bFGF levels in preoperative and postoperative urine samples from 97 patients with Wilms' tumor. Preoperative urine samples (n = 97), early postoperative samples obtained from 1 to 3 weeks after surgery (n = 43), and late postoperative samples obtained from 1 to 6 months after surgery (n = 66) were collected from Wilms' tumor patients at 30 institutions between 1989 and 1993. Urine samples from age-matched controls (n = 17) were also obtained. The bFGF levels were determined in duplicate by a competitive sandwich ELISA capable of measuring bFGF at the pg/ml level. Samples were normalized for creatinine content. Urinary bFGF was elevated in 42% of preoperative samples when compared to controls (>90th percentile of normal). Patients with stage III, IV, and V disease had significantly higher preoperative levels of urinary bFGF when compared to patients with stage I and II disease (P < 0.01). Patients with relapse or persistent disease had significantly elevated late postoperative bFGF levels when compared to disease-free patients and controls (P < 0.05). Thus, in patients with Wilms' tumor, elevated preoperative urinary bFGF levels raise the suspicion of aggressive disease while elevated postoperative levels may indicate recurrence or persistence of disease. These data suggest that bFGF is a biological marker for Wilms' tumor and may have a role in the evaluation of patients with this disease.
Nonlinear ICA of temporally dependent stationary sources (2017)

We develop a nonlinear generalization of independent component analysis (ICA) or blind source separation, based on temporal dependencies (e.g. autocorrelations). We introduce a nonlinear generative model where the independent sources are assumed to be temporally dependent, non-Gaussian, and stationary, and we observe arbitrarily nonlinear mixtures of them. We develop a method for estimating the model (i.e. separating the sources) based on logistic regression in a neural network which learns to discriminate between a short temporal window of the data vs. a temporal window of temporally permuted data. We prove that the method estimates the sources for general smooth mixing nonlinearities, assuming the sources have sufficiently strong temporal dependencies, and these dependencies are in a certain way different from dependencies found in Gaussian processes. For Gaussian (and similar) sources, the method estimates the nonlinear part of the mixing. We thus provide the first rigorous and general proof of identifiability of nonlinear ICA for temporally dependent sources, together with a practical method for its estimation.
Processing of Oxide Composites with Three‐Dimensional Fiber Architectures (2009)

Fabrication of oxide fiber composites is accompanied by the development of drying cracks in the matrix following slurry infiltration. The cracks are a result of the inherent shrinkage in particle compacts during drying coupled with the mechanical constraints imposed on the matrix by the fibers. The effects are most pronounced in systems with three‐dimensional fiber architectures. A mitigation strategy based on the addition of coarse matrix particles to the fine particulates has been devised and demonstrated. Among the various implementation strategies explored, the most effective involves combining the two particle types (coarse and fine) into a single slurry and coinfiltrating the slurry through sequential vibration‐ and vacuum‐assisted processes. Regardless of the infiltration route, the SiC particles have no apparent detrimental effect on the fiber bundle properties. Additionally, they increase the through‐thickness thermal diffusivity by 50%–100%.
Regulation of somatostatin receptor 4-mediated cytostatic effects by CD26 in malignant pleural mesothelioma (2014)

Combination therapy with humanised anti-CD26 mAb and SSTR4 agonist may therefore potentiate anti-tumour effect on MPM.
The Cell Membrane and Cell Signals as Targets in Cancer Chemotherapy AACR, EORTC, and BACR Special Conference in Cancer Research (1990)

Summary The final session of the meeting was an open and frank discussion of ways in which it might be possible to use the targets that had been discussed at the meeting for new anticancer drug development and of what the potential problems of this approach were. A consensus was reached that, while most work to date had focused on mechanisms of growth control in normal cells, future efforts should be made simultaneously on two fronts. First, and perhaps self-evidently, we need to increase the sophistication of our understanding of the differences in membrane biology and signalling mechanisms that exist between normal and tumor cells. The second stage is expected to follow naturally from the first, namely the development of agents that could successfully exploit these differences for the purposes of chemotherapy. Many of the drugs discussed at the meeting were discovered by random screening or by molecular modification of existing agents, and this work predated attempts to use membrane and signalling targets for cancer drug development. The actions of such drugs on the cell membrane had been discovered serendipitously and only following some understanding of the basic biology of membrane signal translation. The next period of drug development will focus on agents specifically directed to cell membrane and signalling targets. This promises to be an exciting phase of cancer chemotherapy, with some attention focused away from the traditional sites for anticancer drug action. Naturally, this effort will require the concerted interdisciplinary collaboration of basic molecular biologists and cell physiologists with innovative chemists, cancer pharmacologists, experimental chemotherapists, and clinicians. This first international meeting showed how specialists in these different areas can be brought together successfully to assess progress, define problems, and indicate avenues in which real advances are to be made. The ultimate success of this approach will be judged by future advances made in new drug development, but most of the meeting participants left with a sense of high anticipation and returned to their laboratories with new ideas. In anticipation of these advances, a second international meeting is planned in 3 years time.
Population study of dihydropyrimidine dehydrogenase in cancer patients. (1994)

From the present study, it appears that total DPD deficiency is a rare event. Although pretreatment DPD activity cannot be a useful indicator for improving FU dose adaptation strategy, the identification of severe DPD deficiency (< 0.100 nmol/min/mg protein) could lead to starting the treatment with a markedly reduced FU dose or even to using an alternative chemotherapy regimen.
Cu<sub>2</sub>O nanoparticle-catalyzed tandem reactions for the synthesis of robust polybenzoxazole (2022)

We report the synthesis of Cu<sub>2</sub>O nanoparticles (NPs) by controlled oxidation of Cu NPs and the study of these NPs as a robust catalyst for ammonia borane dehydrogenation, nitroarene hydrogenation, and amine/aldehyde condensation into Schiff-base compounds. Upon investigation of the size-dependent catalysis for ammonia borane dehydrogenation and nitroarene hydrogenation using 8-18 nm Cu<sub>2</sub>O NPs, we found 13 nm Cu<sub>2</sub>O NPs to be especially active with quantitative conversion of nitro groups to amines. The 13 nm Cu<sub>2</sub>O NPs also efficiently catalyze tandem reactions of ammonia borane, diisopropoxy-dinitrobenzene, and terephthalaldehyde, leading to a controlled polymerization and the facile synthesis of polybenzoxazole (PBO). The highly pure PBO (<i>M</i><sub>w</sub> = 19 kDa) shows much enhanced chemical stability than the commercial PBO against hydrolysis in boiling water or simulated seawater, demonstrating a great potential of using noble metal-free catalysts for green chemistry synthesis of PBO as a robust lightweight structural material for thermally and mechanically demanding applications.
Efficacy of Every-Other-Day Administration of Conjugated Equine Estrogen and Medroxyprogesterone Acetate on Gonadotropin-Releasing Hormone Agonists Treatment in Women with Endometriosis (2001)

We performed a randomized controlled study to determine the efficacy of add-backed therapy by every-other-day administration of 0.625 mg conjugated equine estrogen (CEE) and 2.5 mg medroxyprogesterone acetate (MPA) on GnRH agonists (GnRH-a) treatment in Japanese women with symptomatic endometriosis. At the end of treatment, serum estrone and estradiol levels in the add-back group (n = 11) were significantly higher than those in the control group (n = 10). The assessment of Beecham classification by bimanual examination, serum CA-125 levels, and the frequency of genital bleeding revealed no significant differences between the two groups. The add-back group showed reduced Kupperman indices relative to those of the control group, and could prevent the loss of bone density. These findings led to a conclusion that GnRH-a therapy added back by every-other-day administration of 0.625 mg CEE and 2.5 mg MPA was a safe and effective treatment for Japanese women with endometriosis.