gebhart/patrepeval huggingface dataset:
Ultraviolet vision and foraging in terrestrial vertebrates (2002)

Tetrachromatic colour vision, based on four ‘main’ colours and their combinations, is probably the original colour vision in terrestrial vertebrates. In addition to human visible waveband of light (400–700 nm) and three main colours, it also includes the near ultraviolet part of light spectrum (320–400 nm). The ecological importance of ultraviolet (UV) vision in animals has mainly been studied in the context of intra‐ and inter‐sexual signalling, but recently the importance of UV vision in foraging has received more attention. Foraging animals may use either UV cues (reflectance or absorbance) of food items or UV cues of the environment. So far, all diurnal birds studied (at least 35 species), some rodents (4 species), many reptilians (11 species) and amphibians (2 species) are likely able to see near UV light. This probably allows e.g. diurnal raptors as well as frugivorous, nectarivorous and insectivorous birds to use foraging cues invisible to humans. The possible role of UV cues and existing light conditions should be taken into account when food selection of vertebrate animals is studied, particularly, in experiments with artificial food items.
Chemiluminescent determination of choline in cerebrospinal fluid and red blood cells (1988)

The concentration of choline in the cerebrospinal fluid (CSF) of patients affected by primary dementia and in red blood cells (RBC) of depressed patients before and after treatment with lithium salts was determined using a chemiluminescent assay. The mean CSF concentration of choline was found to be 60 pmoles/ml (SD = 20 pmoles/ml) and this was lower than values obtained previously by spectrophotometric-colorimetric methods. Mean RBC choline concentrations before and after therapy with lithium salts were 20 nmoles/ml (SD = 16 nmoles/ml and 328 nmoles/ml (SD = 206 nmoles/l) respectively and these are similar to those reported previously (obtained by chemiluminescent and non-chemiluminescent methods).
Field emission mitigation in X-band silicon-etched cavity resonators (2016)

An edge-smoothing technique for decreasing field emission and therefore increasing power handling in silicon-based cavity resonators is introduced for the first time in this paper. Specifically, this edge-smoothing process is performed in loaded evanescent-mode resonators by oxidizing the silicon surface before metal coating is applied. This process substantially decreases the cavity-etch-induced edge roughness particularly at the edges of the cavity-loading post where the electric field is the strongest inside the resonant cavity. Experimental results demonstrate that the presented technique results in a 2× power improvement (from 14.7 W to 29.4 W) for a high-quality (Qu = 558) demonstration-vehicle 11.15-GHz resonator with a 15-μm over-the-post air gap. In both the original and improved resonators, an abrupt 10-16 dB increase in loss is observed when gas breakdown inside the resonant cavity occurs. The simple yet effective edge-smoothing process is a critical technology advancement for cavity-based resonators since they are important building blocks in widely-tunable high-Q reconfigurable filters.
A screening of curcumin derivatives for antibacterial phototoxic effects studies on curcumin and curcuminoids. XLIII. (2011)

Curcumin, bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione, has potential as a photosensitiser for photodynamic treatment of localised superficial infections in e.g., the mouth or skin. The aim of the present study was to evaluate the in vitro antibacterial phototoxic potential of a series of five curcumin derivatives. The gram-positive Enterococcus faecalis and the gram-negative Escherichia coli were used as bacterial models. The bacteria were exposed to curcuminoid preparations in two concentrations (2.5 and 25.0 microM) in combination with a constant irradiation dose (5 J/cm2). The UV-VIS absorption spectrum of the curcuminoids was in the same range as curcumin, 300-500 nm. Compound 1 (dimethoxycurcumin; C1) and compound 3 (bisdemethoxycurcumin; C3) were strongly phototoxic towards E. faecalis (no surviving bacteria) and showed a lower but significant effect towards E. coli (< or = 0.5 log reductions and 1 - 4 log reductions, respectively). Compound 2 (C2) and compound 4 (C4) in combination with blue light reduced the colony forming ability of E. faecalis (approximately 1-4 log reductions). The phototoxic effect of the curcuminoids varied with concentration, and for compounds C1, C2 and C3 it was further influenced by the addition of polyethylene glycol 400 (PEG 400) to the preparations. 2,6-Divanillylidenecyclohexanone (C5) showed very low phototoxic potential (< 0.2 log reductions) under the conditions used in the present study. The addition of polyethylene glycol 400 (PEG 400) seemed to increase the solubility of compound C1, C3 and C5 in phosphate buffered saline (PBS). This investigation demonstrates the importance and influence of the substituents on the phenolic rings and the keto-enol moiety for the phototoxic potential of curcumin and its derivatives.
Ferromagnetic- and Superconducting-like Behavior of Graphite (1999)

We have identified ferromagnetic- and superconducting-like magnetization hysteresis loops in highly oriented pyrolytic graphite samples below and above room temperature. We also found that both behaviors are very sensitive to low-temperature -- as compared to the sample synthesis temperature -- heat treatment. The possible contribution of magnetic impurities and why these do not appear to be the reason for the observed phenomena is discussed.
Participation of oligochlorobenzenes in the base-catalyzed halogen dance (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTParticipation of oligochlorobenzenes in the base-catalyzed halogen danceMartin H. Mach and Joseph F. BunnettCite this: J. Org. Chem. 1980, 45, 23, 4660–4666Publication Date (Print):November 1, 1980Publication History Published online1 May 2002Published inissue 1 November 1980https://pubs.acs.org/doi/10.1021/jo01311a022https://doi.org/10.1021/jo01311a022research-articleACS PublicationsRequest reuse permissionsArticle Views852Altmetric-Citations23LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Runaway cell death, but not basal disease resistance, in <i>lsd1</i> is SA‐ and <i>NIM1/NPR1</i>‐dependent (2002)

LSD1 was defined as a negative regulator of plant cell death and basal disease resistance based on its null mutant phenotypes. We addressed the relationship between lsd1-mediated runaway cell death and signaling components required for systemic acquired resistance (SAR), namely salicylic acid (SA) accumulation and NIM1/NPR1. We present two important findings. First, SA accumulation and NIM1/NPR1 are required for lsd1-mediated runaway cell death following pathogen infection or application of chemicals that mimic SA action. This implies that lsd1-dependent cell death occurs 'downstream' of the accumulation of SA. As SA application triggers runaway cell death in lsd1 but not wild-type plants, we infer that LSD1 negatively regulates an SA-dependent signal leading to cell death. Thus SA is both a trigger and a required mediator of lsd1 runaway cell death. Second, neither SA accumulation nor NIM1/NPR1 function is required for the basal resistance operating in lsd1. Therefore LSD1 negatively regulates a basal defense pathway that can act upstream or independently of both NIM1/NPR1 function and SA accumulation following avirulent or virulent pathogen challenge. Our data, together with results from other studies, point to the existence of an SA-dependent 'signal potentiation loop' controlling HR. Continued escalation of signaling in the absence of LSD1 leads to runaway cell death. We propose that LSD1 is a key negative regulator of this signal potentiation.
The effects of a lesion or a peripheral nerve graft on GAP-43 upregulation in the adult rat brain: an in situ hybridization and immunocytochemical study (1995)

We have sought to determine (1) if thalamic neurons upregulate the growth associated protein GAP-43 as a response to injury, or if a peripheral nerve graft is required to induce, enhance or sustain such a response, and (2) if thalamic neurons with different regenerative potentials also display different GAP-43 responses. Levels of GAP-43 protein (detected by LM and EM immunohistochemistry) and of GAP-43 mRNA (detected by in situ hybridization) were compared in the thalamus of adult rats between 1 d and 180 d after making a stab lesion or after implanting a peripheral nerve autograft. Stab injury is a sufficient stimulus to cause a transient upregulation in GAP-43 expression by neurons in the thalamus (both around the graft tip and in particular in the thalamic reticular nucleus) in the first week after injury but this response is both prolonged, and enhanced in the presence of a peripheral nerve graft. In addition, we demonstrate directly, by double labelling, that neurons of the thalamic reticular nucleus displaying high levels of the mRNA for GAP-43, have axons regenerating in the distal portion of the graft. These findings lend direct support to the hypothesis that upregulation of the GAP-43 gene is essential for prolonged regenerative axonal growth. We also demonstrate GAP-43 protein in graft Schwann cells and in brain astrocytes close to the site of graft implantation.
Effects of olfactory training in patients with olfactory loss (2009)

Compared to baseline, training patients experienced an increase in their olfactory function, which was observed for the Sniffin' Sticks test score and for thresholds for the odors used in the training process. In contrast, olfactory function was unchanged in patients who did not perform olfactory training. The present results indicate that the structured, short-term exposure to selected odors may increase olfactory sensitivity.
Diode Laser Arrays For Optical Pumping Of Nd:Yag Lasers (1987)

Considerable progress has been made in the technology of producing laser diode arrays for pumping of solid state lasers. Monolithic linear CW arrays with powers of more than 5 watts have been produced and used to pump rod geometry lasers. Area arrays with pulsed power densities of more than 2.5 kilowatts per square centimeter, have been demonstrated. By carefully designing and packaging the array, the same basic diode structure can be used to produce both types of arrays.
Rapeseed meal‐glucosinolates and their antinutritional effects Part 1. Rapeseed production and chemistry of glucosinolates (1993)

This review, which will be presented in seven parts is concerned with the use of rapeseed meal as an animal feeding stuff. The presence of glucosinolates in the meal limits its use due to a number of antinutritional and physiological effects. Whilst not in itself exhaustive, this review updates earlier reviews by reference to recent papers on the above topics. In this first paper the history of the crop and the current production situation are presented and the nature of glucosinolates and methods for their analysis are reviewed in order to facilitate a better appreciation of the problems referred in later sections.
An Energy Efficiency Feature Survey of the Intel Haswell Processor (2015)

The recently introduced Intel Xeon E5-1600 v3 and E5-2600 v3 series processors -- codenamed Haswell-EP -- implement major changes compared to their predecessors. Among these changes are integrated voltage regulators that enable individual voltages and frequencies for every core. In this paper we analyze a number of consequences of this development that are of utmost importance for energy efficiency optimization strategies such as dynamic voltage and frequency scaling (DVFS) and dynamic concurrency throttling (DCT). This includes the enhanced RAPL implementation and its improved accuracy as it moves from modeling to actual measurement. Another fundamental change is that every clock speed above AVX frequency -- including nominal frequency -- is opportunistic and unreliable, which vastly decreases performance predictability with potential effects on scalability. Moreover, we characterize significantly changed p-state transition behavior, and determine crucial memory performance data.
Occurrence of the human tumor-specific antigen structure Gal 1-3GalNAc - (Thomsen-Friedenreich) and related structures on gut bacteria: Prevalence, immunochemical analysis and structural confirmation (2011)

The Thomsen-Friedenreich antigen (TF; CD176, Galβ1-3GalNAcα-) is a tumor-specific carbohydrate antigen and a promising therapeutic target. Antibodies that react with this antigen are frequently found in the sera of healthy adults and are assumed to play a role in cancer immunosurveillance. In this study, we examined the occurrence of α-anomeric TF (TFα) on a large variety of gastrointestinal bacteria using a novel panel of well-characterized monoclonal antibodies. Reactivity with at least one anti-TF antibody was found in 13% (16 of 122) of strains analyzed. A more in-depth analysis, using monoclonal antibodies specific for α- and β-anomeric TF in combination with periodate oxidation, revealed that only two novel Bacteroides ovatus strains (D-6 and F-1), isolated from the faeces of healthy persons by TF-immunoaffinity enrichment, possessed structures that are immunochemically identical to the true TFα antigen. The TF-positive capsular polysaccharide structure of strain D-6 was characterized by mass spectrometry, monosaccharide composition analysis, glycosidase treatments and immunoblot staining with TFα- and TFβ-specific antibodies. The active antigen was identified as Galβ1-3GalNAc-, which was α-anomerically linked as a branching structure within a heptasaccharide repeating unit. We conclude that structures immunochemically identical to TFα are extremely rare on the surface of human intestinal bacteria and may only be identifiable by binding of both antibodies, NM-TF1 and NM-TF2, which recognize a complete immunomolecular imprint of the TFα structure. The two novel B. ovatus strains isolated in this study may provide a basis for the development of TF-based anti-tumor vaccines.
A parallel 32&#x00D7;32 time-to-digital converter array fabricated in a 130 nm imaging CMOS technology (2009)

We report on the design and characterization of a 32 × 32 time-to-digital converter (TDC) array implemented in a 130 nm imaging CMOS technology. The 10-bit TDCs exhibit a timing resolution of 119 ps with a timing uniformity across the entire array of less than 2 LSBs. The differential- and integral non-linearity (DNL and INL) were measured at ± 0.4 and ±1.2 LSBs respectively. The TDC array was fabricated with a pitch of 50µm in both directions and with a total TDC area of less than 2000µm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . The characteristics of the array make it an excellent candidate for in-pixel TDC in time-resolved imagers for applications such as 3-D imaging and fluorescence lifetime imaging microscopy (FLIM).
Genetics of osteoporosis (2007)

Osteoporosis is a common disease with a strong genetic component characterised by reduced bone mass and an increased risk of fragility fractures. Twin and family studies have shown that genetic factors contribute to osteoporosis by influencing bone mineral density (BMD), and other phenotypes that are associated with fracture risk, although the heritability of fracture itself is modest. Linkage studies have identified several quantitative trait loci that regulate BMD but most causal genes remain to be identified. In contrast, linkage studies in monogenic bone diseases have been successful in gene identification, and polymorphisms in many of these genes have been found to contribute to the regulation of bone mass in the normal population. Population-based studies have identified polymorphisms in several candidate genes that have been associated with bone mass or osteoporotic fracture, although individually these polymorphisms only account for a small amount of the genetic contribution to BMD regulation. Environmental factors such as diet and physical activity are also important determinants of BMD, and in some cases specific nutrients have been found to interact with genetic polymorphisms to regulate BMD. From a clinical standpoint, advances in knowledge about the genetic basis of osteoporosis are likely to be important in increasing the understanding of the pathophysiology of the disease; providing new genetic markers with which to assess fracture risk and in identifying genes and pathways that form molecular targets for the design of the next generation of drug treatments.
Clinical assessment of accommodative facility in symptomatic and asymptomatic individuals. (1985)

Clinical assessment of accommodative facility, using +/- 2.00 diopter flippers monocularly, was performed in asymptomatic and symptomatic populations in either single test sessions or multiple daily test sessions. In single session results, there was a trend for the average accommodative flipper rate to decrease as symptom level increased. The cut-off symptomatic/asymptomatic accommodative flipper rate was about 11 cycles per minute. In multiple session results, the average accommodative flipper rate, independent of symptom level, took approximately one week to asymptote to a stable level, with performance remaining at this level two weeks after termination of daily test sessions. Variability in daily flipper rate increased as symptom level increased. These results demonstrate the clinical usefulness of the +/- 2.00 diopter monocular flipper test in the screening for accommodative dysfunction.
Improving intelligibility of a 300 b/s segment vocoder (2002)

The problem of increasing the intelligibility of a 300 b/s segment vocoder is addressed by investigating: (1) new line spectral pair (LSP)-based distance measures and (2) new structures and construction methods for segment codebooks. A variety of new distance measures is evaluated, and it is found that, after tuning, all of the distance measures provide almost equal intelligibility, indicating that some other factor, such as codebook template quality, is limiting performance. In an effort to improve the codebook, multiple duration-dependent codebooks constructed by selecting phonetically labeled segments from the TIMIT database are examined.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
The translational regulator CPEB1 provides a link between dcp1 bodies and stress granules (2005)

The cytoplasmic polyadenylation element-binding protein (CPEB) has been characterized in Xenopus laevis as a translational regulator. During the early development, it behaves first as an inhibitor and later as an activator of translation. In mammals, its closest homologue is CPEB1 for which two isoforms, short and long, have been described. Here we describe an additional isoform with a different RNA recognition motif, which is differentially expressed in the brain and ovary. We show that all CPEB1 isoforms are found associated with two previously described cytoplasmic structures, stress granules and dcp1 bodies. This association requires the RNA binding ability of the protein, whereas the Aurora A phosphorylation site is dispensable. Interestingly, the rck/p54 DEAD box protein, which is known as a CPEB partner in Xenopus and clam, and as a component of dcp1 bodies in mammals, is also present in stress granules. Both stress granules and dcp1 bodies are involved in mRNA storage and/or degradation, although so far no link has been made between the two, in terms of neither morphology nor protein content. Here we show that transient CPEB1 expression induces the assembly of stress granules, which in turn recruit dcp1 bodies. This dynamic connection between the two structures sheds new light on the compartmentalization of mRNA metabolism in the cytoplasm.
Metal to ligand charge transfer induced DNA photobinding in a Ru(<scp>ii</scp>)–Pt(<scp>ii</scp>) supramolecule using red light in the therapeutic window: a new mechanism for DNA modification (2011)

The Ru(II)–Pt(II) supramolecular complex, [(Ph2phen)2Ru(dpp)PtCl2]2+, displays a new mechanism for DNA modification: photobinding through a 3MLCT excited state. Gel shift analysis, selective DNA precipitation, and DNA melting point experiments support efficient covalent DNA binding following visible light excitation.
One pot chemical vapor deposition of high optical quality large area monolayer Janus transition metal dichalcogenides (2022)

We report one-pot chemical vapor deposition (CVD) growth of large-area Janus SeMoS monolayers, with the asymmetric top (Se) and bottom (S) chalcogen atomic planes with respect to the central transition metal (Mo) atoms. The formation of these two-dimensional semiconductor monolayers takes place upon the thermodynamic equilibrium-driven exchange of the bottom Se atoms of the initially grown MoSe2 single crystals on gold foils with S atoms. The growth process is characterized by complementary experimental techniques including Raman and X-ray photoelectron spectroscopy and the growth mechanisms are rationalized by first principle calculations. The remarkably high optical quality of the synthesized Janus monolayers is demonstrated by optical and magneto-optical measurements which reveal the strong exciton-phonon coupling and enable to obtain the exciton g-factor of -3.3.
Performance and Cost Analysis of Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry for Routine Identification of Yeast (2011)

Matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry was compared to phenotypic testing for yeast identification. MALDI-TOF mass spectrometry yielded 96.3% and 84.5% accurate species level identifications (spectral scores, ≥ 1.8) for 138 common and 103 archived strains of yeast. MALDI-TOF mass spectrometry is accurate, rapid (5.1 min of hands-on time/identification), and cost-effective ($0.50/sample) for yeast identification in the clinical laboratory.