gebhart/patrepeval huggingface dataset:
The Creation Phase in Network Slicing: From a Service Order to an Operative Network Slice (2018)

Network slicing is considered a key mechanism to serve the multitude of tenants (e.g. vertical industries) targeted by forthcoming 5G systems in a flexible and cost-efficient manner. In this paper, we present a SDN/NFV architecture with multi-tenancy support. This architecture enables a network slice provider to deploy network slice instances for multiple tenants on-the-fly, and simultaneously provision them with isolation guarantees. Following the Network Slice as-a-Service delivery model, a tenant may access a Service Catalog, selecting the slice that best fits its needs and ordering its deployment. This work provides a detailed view on the stages that a network slice provider must follow to deploy the ordered network slice instance, accommodating it into a multi-domain infrastructure, and putting it operative for tenant's consumption. These stages address critical issues identified in the literature, including (i) the mapping from high-level service requirements to network functions and infrastructure requirements, (ii) the admission control, and (iii) the specific information a network slice descriptor should have. With the proposed architecture and the recommended set of stages, network slice providers can deploy (and later operate) slice instances with great agility, flexibility, and full automation.
An endogenous ligand for the central sulfonylurea receptor (1988)

An endogenous ligand for the rat central sulfonylurea receptor has been evidenced in the rat central nervous system. The characteristics of this ligand (extractibility, non-dialysability, chromatographic behaviour on different media, sensitivity to proteases) indicate that it is a neutral to slightly basic peptide.
INTRACRANIAL CONVERSION OF LINOLEIC ACID TO ARACHIDONIC ACID: EVIDENCE FOR LACK OF Δ<sup>8</sup> DESATURASE IN THE BRAIN (1976)

Abstract Eleven‐day old rats were given intracranial injection of [1‐ 14 C]linoleic acid (all cis 9,12 octadecadienoic acid) and sacrificed after 8 h. Analysis of brain fatty acids showed that 16:0, 18:2, 20:2,20:3 and 20:4 were labeled. Separation by AgN03:Si02 TLC plates followed by reductive ozonolysis characterized thc polyunsaturated fatty acids as 18:2 (Δ9,12), 20:2 (Δ11,14), 20:3 (Δ8,11,14) and 20:4 (Δ5,8,11,14). A smaller amount of 18:3 (Δ6,9,12) was also identified. This initially suggested 20:2 (A1 1,14) as an intermediate in the optional pathway of biosynthesis of arachidonate. However, when [l‐14C]eicosadienoic acid (Δ1 1,141 itself was injected in the brain it was converted to 20:3 (Δ5,11,14) (a non‐methylene interrupted double bond system) rather than the expected 20:3 (Δ8,11,14). Only a small amount of arachidonate was formed from 20:2 (Δ11,14). Thus it was concluded that 20:2 (Δ11,14) was not an intermediate in the pathways of arachidonate biosynthesis due to lack of Δ 5 desaturase in thc brain which agrees with the findings of SPKECRER & LEE (1975) in rat liver.
Synthesis and properties of the .alpha.-keto acids (1983)

ADVERTISEMENT RETURN TO ISSUEPREVArticleSynthesis and properties of the .alpha.-keto acidsArthur J. L. Cooper, James Z. Ginos, and Alton MeisterCite this: Chem. Rev. 1983, 83, 3, 321–358Publication Date (Print):June 1, 1983Publication History Published online1 May 2002Published inissue 1 June 1983https://doi.org/10.1021/cr00055a004Request reuse permissionsArticle Views4371Altmetric-Citations212LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (4 MB) Get e-Alertsclose Get e-Alerts
ChemInform Abstract: Syntheses of α‐Pyrones Using Gold‐Catalyzed Coupling Reactions. (2011)

Abstract The method is highly suitable for the preparation of multisubstituted pyrone units.
Expert systems a user's perspective of some current tools (1982)

The purpose of this paper is to report on one user's experience with several of the software tools for building an expert system. To the best of the author's knowledge, this is the first time a number of different expert system building tools have been applied to a single problem by a single analyst. A similar single problem/different tool experiment was performed at the Expert Systems Workshop in 1980, but each tool was used by its own proponents on the given problem.
Peer Reviewed: Plant-Derived Materials for Metal Ion-Selective Binding and Preconcentration (1996)

ADVERTISEMENT RETURN TO ISSUEPREVFeaturesNEXTPeer Reviewed: Plant-Derived Materials for Metal Ion-Selective Binding and Preconcentration Biomass materials can be used to remove metals from contaminated water Lawrence R. Drake and Gary D. RaysonCite this: Anal. Chemi. 1996, 68, 1, 22A–27APublication Date (Web):May 24, 2011Publication History Published online24 May 2011Published inissue 1 January 1996https://pubs.acs.org/doi/10.1021/ac9618029https://doi.org/10.1021/ac9618029research-articleACS PublicationsRequest reuse permissionsArticle Views211Altmetric-Citations42LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Materials,Metals,Preconcentration Get e-Alerts
Evaluation of the possibilities of using humic acids obtained from lignite in the production of commercial fertilizers (2018)

Technological progress and high market demand contributed to a significant interest in the production of fertilizers based on humic acids. The aim of this study was to evaluate the possibilities of using humic acids obtained from lignite in the production of new commercial products. For this purpose, it is necessary to determine the quality standard requirements for such material. Properties of humic acids depend on source of origin as well as method of its extraction. The humic acids were extracted from polish deposit of lignite–Sieniawa Lubuska by alkaline extraction using for this purpose six kinds of extractants: 0.1 M NaOH and 0.25 M NaOH, 0.1 M KOH and 0.25 M KOH, and 0.1 M Na4P2O7 and 0.25 M Na4P2O7. The humic samples were used in solid powder form and characterized by UV-Vis spectroscopy, 13C NMR spectroscopy, fluorescence spectroscopy, and thermal analysis. The determining factor influencing a degree of humic acids extraction from lignite and their structure is type of extractant. The largest efficiency of extraction (about 50%) was obtained with the use of NaOH solutions. All examined humic acids were generally characterized by simple and heterogeneous molecularly structure with low molecular weight and low aromatic polycondensation. Therefore, it can be concluded that humic acids extracted with NaOH and KOH solutions are less condensed than those extracted with Na4P2O7 solutions. It can suggest that humic acids obtained from lignite using solutions of Na4P2O7 are characterized by a low transformation degree and greater amount of carboxyl groups. Low rank coal can be successfully used in agriculture as a rich source of humic acids. Reagent used in their extraction, apart from high efficiency should have a neutral impact on their structure. Studies on the physicochemical properties of humic acids can be helpful in predicting behaviors of such fertilizer components in the environment and in inventing new products taking the principles of sustainable development into consideration.
Cesium dithiolate based syntheses of keto-functionalized thio-crown ethers employing the novel building block 1,3-dimercaptoacetone. Molecular structures of 2,5,9,12-tetrathia-7-oxo-(13)-m-benzenophane and 1,4,7,10,13-pentathiacyclohexadecan-15-one (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCesium dithiolate based syntheses of keto-functionalized thio-crown ethers employing the novel building block 1,3-dimercaptoacetone. Molecular structures of 2,5,9,12-tetrathia-7-oxo-(13)-m-benzenophane and 1,4,7,10,13-pentathiacyclohexadecan-15-oneJilles J. H. Edema, Jan Buter, Franck S. Schoonbeek, Auke Meetsma, Fre van Bolhuis, and Richard M. KelloggCite this: J. Org. Chem. 1993, 58, 21, 5624–5627Publication Date (Print):October 1, 1993Publication History Published online1 May 2002Published inissue 1 October 1993https://pubs.acs.org/doi/10.1021/jo00073a019https://doi.org/10.1021/jo00073a019research-articleACS PublicationsRequest reuse permissionsArticle Views302Altmetric-Citations20LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Successful Management of Humoral Hypercalcemia of Malignancy in A Patient with Ovarian Cancer (2000)

We present here successful treatment with bisphosphonate pamidronate of a 54-year-old patient with advanced ovarian cancer and humoral hypercalcemia of malignancy, followed by cytoreductive surgery and postoperative chemotherapy. Concentration of serum calcium increased to 16.8 mg/dL and parathyroid hormone-related protein (PTHrP)-intact was remarkably elevated. Interestingly, the 1,25-dihydroxyvitamin D (1,25-DHD) was high in this case. Treatment with bisphosphonate pamidronate was effective for the improvement of hypercalcemia so that she could undergo optimal surgery followed by postoperative chemotherapy. The histochemical examination of PTHrP using anti-human monoclonal antibody showed positive staining in the cancer cells of the ovary.
Before, During, and After Self Injury (2018)

Little is currently known about the repetitive behaviors that take place before, during, and after nonsuicidal self-injury (NSSI). These practice patterns surrounding repetitive self-injury may be part of a habituation process in NSSI. Congruent with the opponent process theory (OPT), the mechanisms through which NSSI is reinforced may include preparation, engagement, and follow-up practice patterns to achieve the desired effect. This may result in increased habituation leading to a change in method and resulting NSSI severity. College students with a history of NSSI (N = 80) completed questionnaires, including an instrument to assess practice patterns around NSSI. High levels of NSSI practice patterns were positively related to various NSSI characteristics and clinical correlates, suggesting higher levels of NSSI severity. Further, NSSI versatility partially explained the relationship between NSSI practice patterns and habituation. Consistent with OPT, practice patterns associated with repetitive NSSI may lead an individual to change methods, fostering habituation to self-injury.
A Role for ZO-1 and PLEKHA7 in Recruiting Paracingulin to Tight and Adherens Junctions of Epithelial Cells (2011)

Paracingulin is a 160-kDa protein localized in the cytoplasmic region of epithelial tight and adherens junctions, where it regulates RhoA and Rac1 activities by interacting with guanine nucleotide exchange factors. Here, we investigate the molecular mechanisms that control the recruitment of paracingulin to cell-cell junctions. We show that paracingulin forms a complex with the tight junction protein ZO-1, and the globular head domain of paracingulin interacts directly with ZO-1 through an N-terminal region containing a conserved ZIM (ZO-1-Interaction-Motif) sequence. Recruitment of paracingulin to cadherin-based cell-cell junctions in Rat1 fibroblasts requires the ZIM-containing region, whereas in epithelial cells removal of this region decreases the junctional localization of paracingulin at tight junctions but not at adherens junctions. Depletion of ZO-1, but not ZO-2, reduces paracingulin accumulation at tight junctions. A yeast two-hybrid screen identifies both ZO-1 and the adherens junction protein PLEKHA7 as paracingulin-binding proteins. Paracingulin forms a complex with PLEKHA7 and its interacting partner p120ctn, and the globular head domain of paracingulin interacts directly with a central region of PLEKHA7. Depletion of PLEKHA7 from Madin-Darby canine kidney cells results in the loss of junctional localization of paracingulin and a decrease in its expression. In summary, we characterize ZO-1 and PLEKHA7 as paracingulin-interacting proteins that are involved in its recruitment to epithelial tight and adherens junctions, respectively.
Discovery of Potent and Selective Inhibitors for ADAMTS-4 through DNA-Encoded Library Technology (ELT) (2015)

The aggrecan degrading metalloprotease ADAMTS-4 has been identified as a novel therapeutic target for osteoarthritis. Here, we use DNA-encoded Library Technology (ELT) to identify novel ADAMTS-4 inhibitors from a DNA-encoded triazine library by affinity selection. Structure-activity relationship studies based on the selection information led to the identification of potent and highly selective inhibitors. For example, 4-(((4-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-6-(((4-methylpiperazin-1-yl)methyl)amino)-1,3,5-triazin-2-yl)amino)methyl)-N-ethyl-N-(m-tolyl)benzamide has IC50 of 10 nM against ADAMTS-4, with >1000-fold selectivity over ADAMT-5, MMP-13, TACE, and ADAMTS-13. These inhibitors have no obvious zinc ligand functionality.
T cell responses to the human papillomavirus type 16 E7 protein in mice of different haplotypes (1992)

The response of murine T cells to the E7 molecule of human papillomavirus type 16 (HPV-16) was studied using eight different mouse strains of six distinct H-2 haplotypes. HPV-16 E7 protein was prepared as a fusion protein with glutathione-S-transferase, purified by affinity chromatography and used for immunization. Cells from the lymph nodes were cultured with whole fusion protein, glutathione-S-transferase or HPV-16 E7 protein synthetic peptides. All the mouse strains tested, with the exception of BALB/c, recognized the E7 molecule, as evidenced by a proliferative response to at least two of the peptides. The profile of responses to peptides varied between and within a strain, but five distinct immunodominant regions could be identified. These regions were defined on the basis of a reaction to one or more peptides in a given part of the E7 molecule by at least four strains. The five regions were encompassed by amino acid residues 1 to 9, 17 to 32, 42 to 59, 62 to 77 and 87 to 98. The findings suggest that in an outbred population, such as man, the E7 molecule of HPV-16 would be recognized by a large proportion of the population. However, the poor response of two mouse strains [B10.RIII (71NS) and BALB/c] could also have a corollary in man.
A Light Illumination Enhancement Device for Photoacoustic Imaging: <i>In Vivo</i> Animal Study (2017)

Photoacoustic (PA) imaging detects acoustic signals generated by thermal expansion of a light-excited tissue or contrast agents. PA signal amplitude and image quality directly depend on the light fluence at the target depth. With conventional PA imaging systems, approximately 30% energy of incident light at the near-infrared region would be lost due to reflection on the skin surface. Such light loss directly leads to a reduction of PA signal and image quality. A new light delivery scheme that collects and redistributes reflected light energy was recently suggested, which is called the light catcher. In our previous study, proof of concept using a finite-element simulation model was shown and a laboratory-built prototype of the light catcher was applied on tissue-mimicking phantoms. In this paper, we present an elaborate prototype of a high-frequency PA probe with the light catcher fabricated using 3-D printing technology, which is conformal to a subcutaneous tumor in mice. The in vivo usefulness of the developed prototype was evaluated in a mouse tumor model. Equipped with the light catcher, PA signal amplitude from the clinical photosensitizer injected into the mouse tumor was enhanced by 33.7%, which is approximately equivalent to the percent light loss due to reflection on the skin.
Hydrogen sensing properties of dielectrophoretically assembled SnO<sub>2</sub>nanoparticles on CMOS-compatible micro-hotplates (2011)

We fabricated nanoparticle-based gas through in situ ac dielectrophoretical assembling of drop-coated SnO(2) nanoparticles to bridge the gap between electrodes with high aspect ratio. While the conventional dielectrophoresis (DEP) adopts a microfluidic system for continuous flow of the solution during the process, we just drop-coated a small amount of solution onto the electrodes and executed in situ DEP for a very short time. This is a very simple, cost-effective, time-saving, and highly reproducible process. We fixed the duration time and applied voltage for the DEP at 1 s and 1 V respectively and changed the frequencies from 1 up to 500 kHz. I-V characteristics of the samples were checked and it was found that DEP samples fabricated at 1 s, 1 V and 150 kHz conditions showed considerably higher connectivity of the nanoparticles. This can be attributed to the excellent step coverage achieved by ac DEP under those conditions. The devices drop-coated and dielectrophoretically assembled at other ac frequency conditions showed poor connectivity. Hydrogen gas sensing properties of the sensors fabricated under 1 s, 1 V and 150 kHz conditions were checked by flowing through 160 ppm H(2). The sensitivity reaches a maximum value of ~ 700% at 350 °C. The response time is ~ 200 s at 350 °C.
50,000 users on an Oracle8 universal server database (1998)

In this paper, we describe the Oracle Large User Population Demonstration and highlight the scalability mechanisms in the Oracle8 Universal Data Server which make it possible to support as many as 50,000 concurrent users on a single Oracle8 database without any middle-tier TP-monitor software. Supporting such large user populations requires many mechanisms for high concurrency and throughput. Algorithms in all areas of the server ranging from process and buffer management to SQL compilation and execution must be designed to be highly scalable. Efficient resource sharing mechanisms are required to prevent server-side resource requirements from growing unboundedly with the number of users. Parallel execution across multiple systems is necessary to allow user-population and throughput to scale beyond the restrictions of a single system. In addition to scalability, mechanisms for high availability, ease-of-use, and rich functionality are necessary for supporting complex user applications typical of realistic workloads. All mechanisms must be portable to a wide variety of installations ranging from desk-top systems to large scale enterprise servers and to a wide variety of operating systems.
A projections onto the overcomplete basis approach for block loss recovery (2002)

We present an error concealment method to recover damaged blocks for block-based image coding schemes. The recovery problem considered in our method is to estimate a larger block, which consists of a damaged block and the undamaged neighborhood, from the undamaged neighborhood. To find an accurate estimate, an overcomplete basis is introduced and an estimate is expressed as a linear combination of the basis vectors. The projections onto the overcomplete basis algorithm is proposed to find the projection coefficients to minimize the squared difference of an estimate and the undamaged neighborhood information. The reconstructed images by the proposed method provide a good subjective quality as well as an objective one.
Dye-Sensitized MoS<sub>2</sub> Photodetector with Enhanced Spectral Photoresponse (2014)

We fabricated dye-sensitized MoS2 photodetectors that utilized a single-layer MoS2 treated with rhodamine 6G (R6G) organic dye molecules (with an optical band gap of 2.38 eV or 521 nm). The proposed photodetector showed an enhanced performance with a broad spectral photoresponse and a high photoresponsivity compared with the properties of the pristine MoS2 photodetectors. The R6G dye molecules deposited onto the MoS2 layer increased the photocurrent by an order of magnitude due to charge transfer of the photoexcited electrons from the R6G molecules to the MoS2 layer. Importantly, the photodetection response extended to the infrared (λ < 980 nm, which corresponded to about half the energy band gap of MoS2), thereby distinguishing the device performance from that of a pristine MoS2 device, in which detection was only possible at wavelengths shorter than the band gap of MoS2, i.e., λ < 681 nm. The resulting device exhibited a maximum photoresponsivity of 1.17 AW(–1), a photodetectivity of 1.5 × 10(7) Jones, and a total effective quantum efficiency (EQE) of 280% at 520 nm. The device design described here presents a significant step toward high-performance 2D nanomaterial-based photodetector.