gebhart/patrepeval huggingface dataset:
BLE Beacons for Internet of Things Applications: Survey, Challenges, and Opportunities (2018)

While the Internet of Things (IoT) is driving a transformation of current society toward a smarter one, new challenges and opportunities have arisen to accommodate the demands of IoT development. Low power wireless devices are, undoubtedly, the most viable solution for diverse IoT use cases. Among such devices, Bluetooth low energy (BLE) beacons have emerged as one of the most promising due to the ubiquity of Bluetooth-compatible devices, such as iPhones and Android smartphones. However, for BLE beacons to continue penetrating the IoT ecosystem in a holistic manner, interdisciplinary research is needed to ensure seamless integration. This paper consolidates the information on the state-of-the-art BLE beacon, from its application and deployment cases, hardware requirements, and casing design to its software and protocol design, and it delivers a timely review of the related research challenges. In particular, the BLE beacon's cutting-edge applications, the interoperability between packet profiles, the reliability of its signal detection and distance estimation methods, the sustainability of its low energy, and its deployment constraints are discussed to identify research opportunities and directions.
Sarape saltillense: de lo textil a lo arquitectónico (2023)

La presente investigación forma parte de un proyecto doctoral y pretende profundizar en el estudio de la prenda del sarape desde diversas vertientes; al definir la iconografía del sarape que se encuentra en la prenda como símbolo y su derivación a la aplicación gráfica en las viviendas del Centro Histórico de Saltillo que fueron modificadas entre 1880 y 1930, gracias a los avances tecnológicos de la época. Todo esto, mediante la investigación teórica, así como desde el punto de vista semiótico para determinar si este registro tangible y material, se traslada de un soporte textil a un soporte arquitectónico que se reafirma como símbolo de identidad saltillense. El abordaje metodológico será de forma estructurada al lograr una aproximación y reflexión desde la teoría de los imaginarios y la semiótica, así como la utilización del método Panofsky (1892-1968) para el análisis visual de los elementos encontrados. Como resultado de esta reflexión y estudio de la información recabada se presenta el análisis visual, interpretativo y analógico de los componentes del sarape en relación con los elementos arquitectónicos encontrados en las viviendas seleccionadas, derivando así la utilización del símbolo como recurso de rescate identitario en la arquitectura de la ciudad de Saltillo.
The Use of Nano-Particles to Produce Iridescent Metallic Effects on Ancient Ceramic Objects (2012)

Nano-sized materials have been often used in the past to realize objects with particular characteristics. One of the most outstanding examples is represented by luster pottery, showing shining surfaces with particular optical properties. Luster was one of the most sophisticated technique for the decoration of majolicas. It consists of a thin metallic film containing silver, copper and other substances, like iron oxide and cinnabar, applied in a reducing atmosphere on a previously glazed ceramic. In such a way, beautiful iridescent reflections of different colours (in particular gold and ruby-red) are obtained. This technique, at first developed in Iraq, was introduced in Italy from Spain. In Italy the potters of the two centres of Gubbio and Deruta, in central Italy, became so expert that nowadays modern artisans are not able to reproduce the wonderful effects obtained during Renaissance. A complete characterization by means of numerous techniques has been carried out on a great number of shards and precious work of arts conserved in many important museums. This allowed to draw some correlations between the preparation technique and the obtained nano-structure.
BACKGROUND (2009)

If aliens had surveyed Earth 10 million years ago (MYA), they might have concluded that our planet not only lacked intelligent life but also had no obvious prospects for acquiring any. After all, how could they have known that East Africa would dry out, forcing some of its hairy tree dwellers to venture onto the plains, walk upright, utter sentences, make tools, and build skyscrapers?
Introduction (2011)

On 27 June 1986, the International Court of Justice pronounced its much-anticipated judgment in the Nicaragua case. For the first time in its history, it gave a direct and elaborate ruling on issues pertaining to the international law on the use of force (Ius ad Bellum), including on the conditions for the exercise of States' right of self-defence. If the Court's approach merits praise for unequivocally affirming that disputes involving the recourse to force are inherently justiciable, it is somewhat puzzling what led the Hague Judges to conclude that ‘[t]here appears now to be general agreement on the nature of the acts which can be treated as constituting armed attacks’, triggering the right of self-defence. Whether it was naïvety, over-confidence or bluff on their part is open to speculation, yet one need not possess the combined legal skills of Grotius and Vattel to understand that it did not completely reflect normative reality.
Theoretical bounds on control-plane self-monitoring in routing protocols (2007)

The distributed routing protocols in use today promise to operate correctly only if all nodes implement the protocol faithfully. A small insignificant set of nodes have, in the past, brought an entire network to a standstill by reporting incorrect route information. The damage caused by these erroneous reports, in some instances, could have been contained since incorrect route reports sometimes reveal themselves as inconsistencies in the state-information of correctly functioning nodes. By checking for such inconsitencies and taking preventive action, such as disregarding selected route-reports, a correctly functioning node could have limited the damage caused by the malfunctioning nodes.
Ligand-Induced G-Quadruplex Polymorphism: A DNA Nanodevice for Label-Free Aptasensor Platforms (2019)

G-Quadruplexes (GQs) serve as popular recognition elements for DNA aptasensors and are incorporated into a DNA nanodevice capable of controlled conformational changes to activate a sensing mechanism. Herein we highlight the utility of a GQ-GQ nanodevice fueled by GQ-specific ligands as a label-free aptasensor detection strategy. The concept was first illustrated utilizing the prototypical polymorphic human telomeric repeat sequence (H-Telo22, d[AG3(T2AG3)3]) that can undergo ligand-induced topology changes between antiparallel, parallel, or hybrid GQ structures. The H-Telo22-ligand interactions served as a model of the GQ-GQ nanodevice. The utility of the device in a real aptasensor platform was then highlighted utilizing the ochratoxin A (OTA) binding aptamer (OTABA) that folds into an antiparallel GQ in the absence and presence of target OTA. Three cationic fluorogenic ligands served as GQ-specific light-up probes and as potential fuel for the GQ-GQ nanodevice by producing an inactive GQ topology (parallel or hybrid) of OTABA. Our findings demonstrate efficient OTA-mediated dye displacement with excellent emission sensitivity for OTA detection when the fluorogenic dyes induce a topology change in OTABA (parallel or hybrid). However, when the fluorogenic dye fails to induce a conformational change in the antiparallel fold of OTABA, subsequent additions of OTA to the aptamer-dye complex results in poor dye displacement with weak emission response for OTA detection. These results are the first to exemplify a ligand-induced GQ-GQ nanodevice as an aptasensor mechanism and demonstrate diagnostic applications for topology-specific GQ binders.
Antiangiogenesis Cocktails -- Stirred or Shaken?: Highlights of the 9th Annual Drug Discovery Technology World Congress; August 8-13, 2004; Boston, Massachusetts (2004)

Research done in the past few years has outlined the critical role played by the vascular endothelial growth factor (VEGF) and angiogenesis in tumor homeostasis and growth.[1-5] Upon engagement of endothelial cell-bound receptors and kinase activation, VEGF promotes survival, proliferation, and migration of targeted cells, all events that contribute to the angiogenic process associated with tumor expansion. Within the VGEF family, VGEF-A binds to the VEGFR-1 and -2, whereas VGEF-B binds only to VEGFR-1.

Leading researchers convened at the 9th Annual Drug Discovery Technology World Congress, recently held in Boston, Massachusetts, to discuss the results achieved so far with first- and second-generation antiangiogenic agents in cancer patients. New options stemming from the association with other agents or metronomic chemotherapy (CT) were put forward and analyzed for their rationale and applicability. A presentation of the preliminary results obtained with the new compounds currently under development concluded this overview of the latest in the antiangiogenesis field.
CrowdInside (2012)

The existence of a worldwide indoor floorplans database can lead to significant growth in location-based applications, especially for indoor environments. In this paper, we present CrowdInside: a crowdsourcing-based system for the automatic construction of buildings floorplans. CrowdInside leverages the smart phones sensors that are ubiquitously available with humans who use a building to automatically and transparently construct accurate motion traces. These accurate traces are generated based on a novel technique for reducing the errors in the inertial motion traces by using the points of interest in the indoor environment, such as elevators and stairs, for error resetting. The collected traces are then processed to detect the overall floorplan shape as well as higher level semantics such as detecting rooms and corridors shapes along with a variety of points of interest in the environment.
The Relationship between CYP3A5~*3 Polymorphism and Drug Adverse Reaction of Pediatric Acute Leukemia (2013)

Objective: To investigate the relationship between CYP3A5*3 and drug adverse reaction of pediatric acute leukemia.Method: 52 acute lymphoblastic leukemia patients were enrolled in this study.PCR-RFLP was used to identify CYP3A5*3 polymorphism,and then collected the data of drug adverse reaction.Results: Main adverse reactions include vomiting,mucosal damage,hematologic damage,and hepatic function damage.The CYP3A5*3 was a high risk factor for leukopenia and mucosal damage.Conclusion: The CYP3A5*3 variant could change gene's function,and then has an impact on the drug elimination,then lead to higher toxicity in clinical.This variant may be used as a predictive marker for higher risk of drug adverse reaction.
LOCALIZED IDENTIFICATION OF STRUCTURES BY KALMAN FILTER (1993)

構造物の局所的な断面に関して, 構造パラメータを評価する方法を提示した. 構造物を, 共通な境界を介して, 2つのサブストラクチャーに分解する. したがって, 構造物は, 1次, 境界, 2次の3種のサブシステムより構成されることになる. 構造パラメータの同定は, 2次システムにおいてなされる. 拡張カルマンフィルターに, 2次システムにおける状態方程式と観測方程式を適用することにより, 2次システムの剛性と減衰パラメータが評価できる. ここで提案した局所的な同定手法を例示するため, 水平せん断力を受けるビルディングを解析した. 構造パラメータの同定は, ビルの1階部分に対して行った.
A performance analysis of coded frequency-hopped OFDMA (2005)

This paper considers the deployment of frequency-hopped OFDMA at the downlink of a cellular system. Each user in the cell is assigned a number of subcarriers by the base-station, which change every OFDM symbol according to deterministic hopping patterns. The construction of the hopping patterns is based on orthogonal Latin squares, that guarantee orthogonal intra-cell multiple access and randomize the inter-cell interference. Properties of Latin squares are derived, which enable us to evaluate analytically the performance of two coded modulation schemes, namely TCM and BICM. Our results demonstrate the effect of the channel parameters, the hopping pattern selection, the interleaver depth and the inter-cell interference on the performance of a coded FH-OFDMA system.
Autofocus survey: a comparison of algorithms (2007)

There are numerous passive contrast sensing autofocus algorithms that are well documented in literature, but some aspects of their comparative performance have not been widely researched. This study explores the relative merits of a set of autofocus algorithms via examining them against a variety of scene conditions. We create a statistics engine that considers a scene taken through a range of focal values and then computes the best focal position using each autofocus algorithm. The process is repeated across a survey of test scenes containing different representative conditions. The results are assessed against focal positions which are determined by manually focusing the scenes. Through examining these results, we then derive conclusions about the relative merits of each autofocus algorithm with respect to the criteria accuracy and unimodality. Our study concludes that the basic 2D spatial gradient measurement approaches yield the best autofocus results in terms of accuracy and unimodality.
Essential Clinical Immunology (2009)

The ways in which we can better understand cancer, HIV, and other autoimmune diseases through clinical immunology are of great interest to practitioners from the student level to the advanced PhD. Designed as an introduction for practitioners and residents. This book focuses on the clinical disease-state level of immunology, beginning with the basic concepts and then detailing the immunological aspects of various disease states involving major organs of the body. It explores how we can better understand disease and its treatment through clinical immunology; each chapter concludes with patterns for future research.
Conformational analysis and synthetic approaches to polydentate perhydro-diazepine ligands for the complexation of gallium(iii) (2013)

Synthetic approaches are reported to polydentate ligands based on 6-phenyl-6-amino-perhydro-1,4-diazepine. The synthetic route devised averts ring-opening reactions, allowing the exocyclic N-substituent to be introduced separately and involves a nitro-Mannich condensation, prior to chemoselective RANEY® nickel reduction. Comparison of the solid-state structures of four synthetic intermediates reveals that the seven-membered ring adopts a preferred twist-chair conformer in the solid state. Solution state NMR experiments highlight a conformational preference for the bulky aryl groups to adopt an equatorial site, pre-disposing the ligand to metal binding, by adoption of a conformation that creates a facial array of the ligand nitrogen atoms. This ligand conformation averts the formation of less stable metal complexes with differing ligation modes, notably in the binding of Ga(3+) to related ligands, where a C-methyl substituent replaces the phenyl group at the quaternary centre.
Endemic tropical spastic paraparesis associated with human T‐lymphotropic virus type I: A clinical and seroepidemiological study of 25 cases (1987)

Tropical spastic paraparesis (TSP) is a common myeloneuropathy with primary and predominant involvement of the pyramidal tract and minimal sensory loss. The epidemic form of TSP is related to toxic nutritional factors, but the endemic form occurs in clusters in tropical areas, especially in India, Africa, the Seychelles, Colombia, and areas of the Caribbean. We describe the clinical and epidemiological features of 25 TSP patients from Martinique (French West Indies) with serum antibodies to human T-lymphotropic virus type I (HTLV-I). Furthermore, all 11 patients who were seropositive for HTLV-I had specific HTLV-I antibodies in their CSF. All were women. The age of onset varied from 25 to 60 years (mean, 45 years). The main clinical features are spastic paraparesis or paraplegia with spasticity of the upper limbs, minimal sensory loss, and bladder dysfunction. Minimal estimated incidence and prevalence are 1 per 100,000 inhabitants per year and 8 per 100,000, respectively. Seventeen percent of the relatives of patients with HTLV-I-associated TSP have HTLV-I antibodies (1 husband and 7 children). In Martinique, the prevalence of HTLV-I antibodies in the general population is about 2% and reaches 10% for neurological disorders other than TSP. Since our initial report, the association between spastic paraparesis and HTLV-I has been confirmed in Jamaica, Colombia, and Japan, suggesting the neurotropism of this lymphotropic human retrovirus.
CELULOSA: UN POLÍMERO DE SIEMPRE CON MUCHO FUTURO (2017)

Dentro de la gran cantidad de sustancias naturales que han sido de un valor significativo a lo largo de todo el desarrollo cientifico – tecnologico de la humanidad se destaca sin lugar a dudas la celulosa, considerada como uno de los polimeros naturales de mayor abundancia en la naturaleza, y que puede ser obtenida desde las mas variadas fuentes entre las que se encuentran: todo tipo de cuerpos vegetales, en diferentes tipos de algas, de la actividad extracelular de multiples tipos de microorganismos y en el caparazon o estructura de algunos animales marinos [1,2].
Presence and cell growth-related variations of glycogen in human colorectal adenocarcinoma cell lines in culture. (1979)

The presence and kinetics of intracellular glycogen levels were studied, in relationship to cell growth, in asynchronous and in synchronized cultures of four human colorectal adenocarcinoma cell lines (HT-29, HRT-18, SW-480, and Caco-2). The results show that a specific pattern of glycogen accumulation occurs during the process of cell growth of the studied cell lines. The kinetics of glycogen accumulation in asynchronous cultures were similar from one cell line to another and were characterized by a low amount in the exponential phase of growth, followed by a 3- to 4-fold increase in the stationary phase. The quantities found in either phase were specific for each cell line. The maximum values found in Caco-2, HRT-18, HT-29, and SW-480 cells were, respectively, 258.5 +/- 6.9 (S.D.), 88.9 +/- 2.6, 87.5 +/- 3, and 17.5 +/- 1.8 microgram of glycogen per mg of proteins. The kinetics of glycogen accumulation during the cell cycle was also studied in synchronized cultures of HT-29 and HRT-18 cell lines. Both cell lines exhibited a common pattern of low glycogen quantities during S, G2, and M followed by an increase beginning with G1 and peaking (2.5 to 3 times the initial values) in the middle of this phase. This was followed by a symmetrical decrease in the second half of G1.
Self-routing crossbar packet switch employing free-space optics for chip-to-chip interconnections (1991)

A nonblocking crossbar network that employs free-space optical interconnections between optoelectronic switching nodes is proposed. The architecture can be implemented using standard electronic technologies for the switching logic, systematic self-electro-optic effect devices for modulators and detectors, and fairly simple optics to connect adjacent chips in the network. Since optical interconnections are only required between adjacent chips, this architecture may have advantages compared with other architectures that have been proposed using optical interconnections between electronic chips. In addition, a simple routing scheme is discussed that permits the optical crossbar network to be operated as a self-routing packet switch. This packet switch provides for contention resolution, priority routing, and automatic increases in the priority of blocked packets. An example illustrating one implementation of the network is then described and analyzed.
Development of a Decarboxylative Palladation Reaction and Its Use in a Heck-type Olefination of Arene Carboxylates (2002)

The development of a palladium-catalyzed decarboxylative coupling reaction of arene carboxylates with olefinic substrates is described. The optimized procedure for decarboxylative palladation employs Pd(O2CCF3)2 as catalyst (0.2 equiv) in the presence of Ag2CO3 (3 equiv) in the solvent 5% DMSO-DMF and proceeds at temperatures of 80-120 degrees C with a wide range of arene carboxylates and alkenes as substrates. The process is proposed to proceed by an initial Ar-SE reaction involving ipso attack of an electrophilic Pd(II) intermediate on an arene carboxylate to form an arylpalladium(II) species with loss of carbon dioxide. This intermediate is then proposed to react with an olefinic substrate by steps common to the Heck coupling process. Reoxidation of the liberated Pd(0) in situ is proposed to establish the catalytic cycle.
Single fluorescent protein-based Ca2+sensors with increased dynamic range (2007)

We believe that expanded dynamic range, high brightness and relatively high pH-stability should make Case12 and Case16 popular research tools both in scientific studies and high throughput screening assays.
DC-DC Converter for Hybrid and All Electric Vehicles (2009)

To realise the full potential of hybrid and all electric vehicle technologies, a step change is required in the performance of the DC-DC converter systems that connect the energy storage device and traction drive. This paper describes the work being done by a consortium to address these performance issues. It describes the requirements of such converters and details the electronics development of high efficiency converter techniques, thermal management design and health monitoring strategies and supports this work showing the results of simulation and prototype testing.
Using Celebrities and Advertising Campaigns to Enhance Learning of Critical Review and Experimental Design, within an Inquiry-Oriented Biomedical Curriculum (2015)

A challenge in learning to become a scientist is gaining skills in critical review and experimental design. Our aim was to measure the effectiveness of an inquiry-oriented learning (IOL) workshop which used popular culture and pseudoscience as stimuli for engagement. The workshop on critical review of scientific literature and best-practice experimental design consisted of a Socratic-seminar (i.e., collaborative, intellectual dialogue facilitated with open-ended questions) and a poster-defence. Students analysed the scientific publication which led Dr Oz (medical doctor and TV host) to falsely claim green coffee bean extract as a ‘miracle’ cure for obesity. Students also designed an experiment to test the effectiveness of an advertising campaign (e.g., Old Spice: ‘The Man Your Man Could Smell Like’) and presented their design in poster format. Students were assessed before and after the workshop. Post-test scores were higher than pre-test scores (51.8 ± 3.8% vs 38.2 ± 3.1%, n = 25, p < 0.0001) and were correlated (p < 0.001) with students’ assignment marks. Students agreed that the workshop developed their ability to critically review scientific literature (79%) and to design experiments (63%). Our findings suggest that an IOL workshop, using popular culture and pseudoscience, improves skills in critical review and experimental design.
Construction of multiple-rate QC-LDPC codes with constant block lengths (2013)

Communication systems often need to support multiple-rate channel coding for different channel conditions.This paper presents a method to construct multiple-rate quasi-cyclic low density parity check(QC-LDPC) codes with constant block lengths to reduce the implementation complexity.This method uses the modified progressive edge-growth and Reed-Solomon(PEG-RS) codes together with row combining to generate parity check matrices for multiple-rate LDPC codes all with the same structure so that they can share hardware resources to reduce the complexity.Simulations show that the multiple-rate QC-LDPC codes outperform those of digital video broadcasting-second generation terrestrial(DVB-T2) for a range of code rates,with the implementation complexity of the multiple-rate decoder similar to that of the single-rate decoder.