gebhart/patrepeval huggingface dataset:
Sodium lauryl sulfate and recurrent aphthous ulcers: A preliminary study (1994)

Sodium lauryl sulfate (SLS), a synthetic detergent commonly used in dentifrices, is an effective denaturant. The aim of the present study was to investigate the effect of SLS in patients with recurrent aphthous ulcers (RAU). Ten patients with multiple minor RAU participated in the study. The mean incidence of RAU was 17.8 during a 3-month period before the study. The patients used a dentifrice containing 1.2% SLS for a test period of 3 months followed by a dentifrice without SLS for the same time period. The results showed a statistically significant decrease in the number of aphthous ulcers from 14.3 after using the SLS-containing dentifrice to 5.1 ulcers after brushing with the SLS-free dentifrice (p < 0.05). It is suggested that the denaturing effect of SLS on the oral mucin layer, with exposure of the underlying epithelium, induces an increased incidence of RAU.
Sufficient condition for the mode mismatch of single photons for scalability of the boson-sampling computer (2014)

The boson sampler proposed by Aaronson and Arkhipov is a nonuniversal quantum computer, which can serve as evidence against the extended Church-Turing thesis. It samples the probability distribution at the output of a linear unitary optical network with indistinguishable single photons at the input. Four experimental groups have already tested their small-scale prototypes with up to four photons. A boson sampler with a few dozens of single photons is believed to be hard to simulate on a classical computer. For scalability of a realistic boson sampler with current technology it is necessary to know the effect of the photon mode mismatch on its operation. Here a nondeterministic model of the boson sampler is analyzed, which employs partially indistinguishable single photons emitted by identical sources. A sufficient condition on the average mutual fidelity $\ensuremath{\langle}\mathcal{F}\ensuremath{\rangle}$ of the single photons is found, which guarantees that the realistic boson sampler outperforms the classical computer. Moreover, the boson-sampler computer with partially indistinguishable single photons is scalable and has more power than classical computers when the single-photon mode mismatch $1\ensuremath{-}\ensuremath{\langle}\mathcal{F}\ensuremath{\rangle}$ scales as $O({N}^{\ensuremath{-}3/2})$ with the total number of photons $N$.
Interconnection between motives and performances of internationalisation processes (2010)

Over the last thirty years, scholars vigorously attempted to theorise internationalisation of the firm based on analysis of firms’ internationalisation processes. Many studies attempt to explain the motives of firms’ decisions to commence internationalisation processes. This is because motives are triggered by both internal and external forces or factors that a firm’s decision-makers take into account when considering whether to initiate the internationalisation process. Scholars in this field argue that although the vast majority of studies around internationalisation processes capture firms’ activities upon actual commencement of the internationalisation process, they overlook the actual factors that lead firms to initiate such processes. This paper attempts to dismantle the internationalisation processes of a cultural firm and to explore interconnection between motives and performances of internationalisation processes. The paper stipulates that firm’s internationalisation processes are interlinked to forces/factors of both internal and external environment.
Learning Context For Text Categorization (2019)

<strong>For more details :ABSTRACT </strong> This paper describes our work which is based on discovering context for text document categorization. The document categorization approach is derived from a combination of a learning paradigm known as relation extraction and an technique known as context discovery. We demonstrate the effectiveness of our categorization approach using reuters 21578 dataset and synthetic real world data from sports domain. Our experimental results indicate that the learned context greatly improves the categorization performance as compared to traditional categorization approaches. <strong>KEYWORDS </strong> Relation Extraction, Context Discovery, Context Feature Matrix, Context Score <strong>Original Source </strong><strong>URL :</strong><strong> http://aircconline.com/ijdkp/V1N6/1611ijdkp02.pdf</strong> <strong>For more </strong><strong>details :</strong><strong> http://airccse.org/journal/ijdkp/vol1.html</strong>
Low Latency Mobile Augmented Reality with Flexible Tracking (2018)

Jaguar is a mobile Augmented Reality (AR) framework that leverages GPU acceleration on edge cloud to push the limit of end-to-end latency for AR systems and enable accurate and large-scale object recognition based on image retrieval. It integrates the emerging AR development tools (e.g., ARCore and ARKit) into its client design for achieving flexible, robust and context-aware object tracking. Our prototype implementation of Jaguar reduces the end-to-end AR latency to ~33 ms and achieves accurate six degrees of freedom (6DoF) tracking. In this demo, we will show that our Jaguar client recognizes movie posters within the camera view by offloading computation intensive tasks to edge cloud and augments these posters with their movie trailers in 3D upon receiving the recognition results.
Acute‐phase serum amyloid A stimulation of angiogenesis, leukocyte recruitment, and matrix degradation in rheumatoid arthritis through an NF‐κB–dependent signal transduction pathway (2005)

Our findings demonstrate the ability of A-SAA to induce adhesion molecule expression, angiogenesis, and matrix degradation, mechanisms that are mediated by NF-kappaB. Targeting A-SAA and its signaling pathways may represent a new therapeutic approach in the treatment of RA.
Bioactivity and stability of endogenous fibrogenic factors in platelet‐rich fibrin (2008)

Platelet-rich fibrin (PRF) is an autologous fibrin sealant (FS) enriched with a platelet concentrate (> 1,000,000 platelets/microL) produced by the automated Vivostat system and used to enhance wound healing. The effects of PRF were compared with supernatant from thrombin-activated platelet concentrate, recombinant human platelet-derived growth factor (rhPDGF) isoforms, and a homologous FS in cultured normal human dermal fibroblasts. Also, the release of selected endogenous growth factors from PRF and their stability against proteolytic degradation were studied. The proliferative effect of PRF exceeded that of FS and rhPDGF-BB, although it was lower than thrombin-activated platelet concentrate possibly due to sustained growth factor release from platelets in PRF. Anti-PDGF antibody blocked the mitogenic effect of rhPDGF-BB but not that of PRF in growth-arrested fibroblasts. PRF promoted secretion of carboxyterminal propeptide of type I collagen into conditioned medium while rhPDGF-AB had no significant effect on collagen biosynthesis. Limited proteolysis of PDGF-AB and no proteolysis of transforming growth factor-beta1 (TGF-beta1) in PRF were observed with trypsin treatment, whereas rhPDGF-AB and rhTGF-beta1 in bovine serum albumin, matching the total protein concentration of PRF, were almost completely degraded after 24 hours at 37 degrees C. To conclude, PRF provides sustained release and protection against proteolytic degradation of endogenous fibrogenic factors important for wound healing.
Fields of aberrant CpG island hypermethylation in Barrett's esophagus and associated adenocarcinoma. (2000)

Esophageal adenocarcinoma (EAC) is thought to develop through a multistage process in which Barrett's metaplasia progresses through low- and high-grade dysplasia to invasive cancer. Transcriptional silencing of tumor suppressor genes by promoter CpG island hypermethylation has been observed in many types of human cancer. Analysis of CpG island hypermethylation in EAC has thus far been limited to the CDKN2A (p16) gene. In this study, we extend the methylation analysis of EAC to include three other genes, APC, CDH1 (E-cadherin), and ESR1 (ER, estrogen receptor alpha), in addition to CDKN2A. Molecular analysis can provide insight into the complex relationships between tissues with different histologies in Barrett's esophagus and associated adenocarcinoma. Therefore, we have mapped the spatial distribution of methylation patterns in six esophagectomy cases in detail. Hypermethylation of the four CpG islands was analyzed by the MethyLight technique in 107 biopsies derived from these six patients for a total of 428 methylation analyses. Our results show that normal esophageal squamous epithelium is unmethylated at all four CpG islands. CDH1 is unmethylated in most other tissue types as well. Hypermethylation of ESR1 is seen at high frequency in inflammatory reflux esophagitis and at all subsequent stages, whereas APC and CDKN2A hypermethylation is found in Barrett's metaplasia, dysplasia, and EAC. When it occurs, hypermethylation of APC, CDKN2A, and ESR1 is usually found in a large contiguous field, suggesting either a concerted methylation change associated with metaplasia or a clonal expansion of cells with abnormal hypermethylation.
A digital filter chip for ECG signal processing (1994)

A VLSI implementation of a linear-phase digital filter for ECG signal processing has been designed. With a sampling rate of 100 Hz, the passband is from 0.5 Hz to 49.5 Hz with 0.5-dB ripple. The filter architecture is based on the use of recursive running-sum blocks, resulting in a very low computational complexity. Module generators have been used in the layout design for high integration density. The circuit has been designed for a 2.0-/spl mu/m double-metal CMOS technology, having about 34000 transistors and a 15.43-mm/sup 2/ chip area.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A Recommendation System Based on Multi-attribute (2016)

In recent years, more and more internet companies trend to fuse their products with personal recommendation functions. Although the idea of this business model satisfies characteristic of Internet industry felicitously, scientists and engineers gradually find out that the effect is worse than they expected. The quality of recommendation is limited by cold start, data sparse, lack of learning contextual aware, and so on. One of the most important drawbacks of existing recommendation systems is that they usually use only rating matrix as useful information and not fully consider item attributes. In this paper, we proposed an optimized recommendation system, which based on modeling of items in a multidimensional space of item's attribute. The presented approach takes item attributes, user preferences and user context into consideration, and is mainly composed of two modules: (1) attribute-latent factor model, which is used to show user latent preference for each attribute, (2) multi-attribute model, which is used to show user preference between all attributes. The research is conducted in a practical application environment, and the preliminary experimental results show the validity of the recommendation.
Alternatively spliced exons of the β tropomyosin gene exhibit different affinities for F-actin and effects with nonmuscle caldesmon (1995)

The rat beta-tropomyosin (TM) gene expresses two isoforms via alternative RNA splicing, namely skeletal muscle beta-TM and fibroblast TM-1. The latter is also expressed in smooth muscle where it corresponds to smooth muscle beta-TM. Skeletal muscle beta-TM contains exons 7 and 10, whereas exons 6 and 11 are used in fibroblasts and smooth muscle. In order to study the properties of the alternatively spliced proteins, recombinant TMs derived from bacterial and insect cell expression systems were produced, including the normal beta gene products, fibroblast TM-1 and beta skeletal muscle TM, two carboxy-terminal chimeric TMs, TM-6/10 and TM-7/11, as well as a carboxyl-truncated version of each, TM-6Cla and TM-7Cla. The purified TM isoforms were used in actin filament association studies. The apparent TM association constants (Ka) were taken as the free concentration at half saturation and were found to be 6 microM for beta Sk TM, 8.5 for TM-6/10, 25 microM for TM-1, and 30 microM for TM-7/11 at an F-actin concentration of 42 microM. For the truncated TMs, the values determined were higher still but the binding was not carried out to full saturation. Isoforms were also produced using the baculovirus-insect cell system which produces proteins with an acetylated amino terminus as is normally found in vivo. This modification significantly enhanced the F-actin association of TM-1 but not the beta skeletal TM or the other isoforms. Fibroblast TM-2 or TM-3, both products of the alpha gene, enhanced the affinity of TM-1 for F-actin, demonstrating different isoforms can act cooperatively on binding to actin. This effect was not detected with the other expressed beta gene products. The presence of 83 kDa nonmuscle caldesmon was found to enhance the binding of TM-1 for F-actin. This effect was dependent on the presence of both exons 6 and 11, as caldesmon had little effect on the other beta gene products. Collectively these results demonstrate TMs differ in their affinity for F-actin, which can be altered by other TMs or actin-binding proteins. The beta tropomyosin isoforms were fluorescently-tagged and microinjected into cultured cells to study their in vivo localization where it was found that each of the full-length TMs bound to microfilaments but, at the light microscopy level, the isoforms were not differentially localized in these fibroblasts.
Amalgamation of Next-Generation Sequencing for Cancer Diagnostic Research (2018)

Next-generation sequencing (NGS) is widely used to sequence large templates of Genome, exome and transcriptome. Over traditional sequencing method it has high resolution and success rates so it is a best option to study cancer. Combination of NGS with bioinformatic tools could be promising approach in cancer research, cancer diagnosis and treatment. In this review paper we have discussed regarding present and future of DNA sequencing in cancer genomics and also challenges faced by researchers is discussed. Keywords: Next-generation sequencing, cancer diagnosis, cancer research Cite this Article Mamta Rani. Amalgamation of Next-Generation Sequencing for Cancer Diagnostic Research. Research & Reviews: A Journal of Bioinformatics . 2018; 5(1): 10–13p.
Synthesis of Optically Active Oxazoline Derivatives via Catalytic Asymmetric Desymmetrization of 1,3‐Diols (2012)

Chiral oxazolines: A synthetic method to prepare optically active oxazolines through a copper-catalyzed asymmetric desymmetrization of 1,3-diols has been successfully developed. This reaction system tolerated a diverse range of substrates to give the desired oxazoline derivatives in good to excellent yields with high enantioselectivities (see scheme). Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Phoneme-dependent NMF for speech enhancement in monaural mixtures (2011)

The problem of separating speech signals out of monaural mixtures (with other non-speech or speech signals) has become increasingly popular in recent times. Among the various solutions proposed, the most popular methods are based on compositional models such as non-negative matrix factorization (NMF) and latent variable models. Although these techniques are highly effective they largely ignore the inherently phonetic nature of speech. In this paper we present a phoneme-dependent NMFbased algorithm to separate speech from monaural mixtures. Experiments performed on speech mixed with music indicate that the proposed algorithm can result in significant improvement in separation performance, over conventional NMF-based separation.
Red blood cell generation from human induced pluripotent stem cells: perspectives for transfusion medicine (2010)

Red blood cells generated from human induced pluripotent stem cells pave the way for future development of allogeneic transfusion products. This could be done by banking a very limited number of red cell phenotype combinations enabling the safe transfusion of a great number of immunized patients.
HGum: Messaging framework for hardware accelerators (2017)

Software messaging frameworks help avoid errors and reduce engineering efforts in building distributed systems by (1) providing an interface definition language (IDL) to specify precisely the structure of the message (i.e., the message schema), and (2) automatically generating the serialization and deserialization functions that transform user data structures into binary data for sending across the network and vice versa. Similarly, a hardware-accelerated system, which consists of host software and multiple FPGAs, could also benefit from a messaging framework to handle messages both between software and FPGA and also between different FPGAs. The key challenge for a hardware messaging framework is that it must be able to support large messages with complex schema while meeting critical constraints such as clock frequency, area, and throughput. In this paper, we present HGum, a messaging framework for hardware accelerators that meets all the above requirements. HGum is able to generate high-performance and low-cost hardware logic by employing a novel design that algorithmically parses the message schema to perform serialization and deserialization. Our evaluation of HGum shows that it not only significantly reduces engineering efforts but also generates hardware with comparable quality to manual implementation.
Conventional versus novel conditions for the in vitro dissolution testing of parenteral slow release formulations: application to doxepin parenteral dosage forms. (1993)

Parenteral slow release formulations of doxepin in lipid vehicles were prepared in the form of suspensions of doxepin hydrochloride, doxepin pamoate and of poly D,L-lactid and poly D,L-lactid-co-glycolide microspheres containing doxepin hydrochloride. The drug particles or the drug containing microspheres were suspended in the vehicles isopropylmyristate or Miglyol. The dissolution rate of the different doxepin formulations was investigated in two flow through cells, a membrane and a non-membrane system, using either plain buffer or human plasma containing buffer as dissolution media, in order to study the influence of dissolution conditions on dissolution rates. An attempt was made to obtain biorelevant dissolution data. In the membrane system a linear relationship between time and percent drug dissolved during the period of investigation was found. Drug release was very slow and incomplete, especially when buffer was used as dissolution medium. Dissolution data from the nonmembrane system were fitted to monoexponential and biexponential models, respectively. Significant differences were found using different modes of formulation positioning and using the two dissolution media. The most rapid release rates were found when the formulations were spread on glass carriers and plasma was used as dissolution medium. It is suggested that this dissolution procedure has physiological relevance.
Polyethyleneimine–nano silica composites: a low-cost and promising adsorbent for CO<sub>2</sub> capture (2014)

Adsorbents for CO<sub>2</sub> captured with nano silica as support were synthesized by impregnating polyethyleneimine (PEI) into nano silica.
REACH (2014)

In Brief Do you truly know how your actions affect others in the workplace? Read how the work-based learning collaborative REACH helps transform care.
Ultrabroadband Three-Dimensional Printed Radial Perfectly Symmetric Gradient Honeycomb All-Dielectric Dual-Directional Lightweight Planar Luneburg Lens (2018)

An ultrabroadband all-dielectric planar Luneburg lens has been designed and fabricated in this study, which is in the form of a radial gradient lightweight honeycomb column. Because of the novel design of a radial symmetric honeycomb-like microstructure in the subwavelength dimension and the radial gradient configuration according to the refractive index distribution of Luneburg lens, the present lens can focus incident plane waves on the opposite side with high convergence, and its operating frequency range is rather broadband, spanning from 6 to 16 GHz. Besides, the all-dielectric honeycomb-like lens is lightweight with a mass density of 0.23 g/cm<sup>3</sup>, and its broadband transmittance is higher than the reported cases consisting of metallic metamaterial or gradient photonic crystal structures. A prototype of the lens is fabricated by using 3D printing techniques, on which the electric near-field distribution and far-field radiation pattern measurements have been carried out, and the aforementioned performances were demonstrated experimentally. It was also observed that for two point sources placed at the edge of the lens whose intersection angle with the center of the lens is 90°, the far-field radiation pattern was still kept highly directional, which means that the lens can generate two highly directional beams simultaneously, and is an efficient double input-double output device.
Expanding access to coronary artery bypass surgery: who stands to gain? (1995)

These results point to a significant overestimation of the benefits of coronary artery bypass surgery by GPs in Northern Ireland and to a need to develop guidelines for referral.
Dosimetric characteristics of a double‐focused miniature multileaf collimator (1999)

The dosimetric characteristics of a double-focused miniature multileaf collimator (mMLC) attached to a Philips SL75/5 linear accelerator (linac) have been investigated. Output factors, percentage depth-dose, penumbra, leaf transmission, and leakage between the leaves were measured for the 6 MV x-ray beam on this accelerator. Because leakage both through and between the leaves is minimal, the linac jaws can be kept fixed while the mMLC leaf configuration is modified for different aperture shapes. This allows for accurate output prediction using the equivalent square formalism. Percent depth-dose measured for fields defined by the mMLC show little deviation from the percent depth-dose measured for fields defined by the machine jaws or Lipowitz metal blocks. Because the mMLC matches beam divergence in both directions, allows minimal beam transmission, and has a large source-to-collimator distance, the penumbra is sharper for fields defined by the mMLC than for fields defined by the linac jaws or Lipowitz metal blocks. Based on these data, dose calculations for mMLC-defined fields can be applied with no change in procedures from those used for fields defined using conventional methods.