gebhart/patrepeval huggingface dataset:
Session 6 overview: Image sensors and displays: IMMD subcommittee (2015)

The session presents recent advancements in the field of image sensors and capacitive touch-sensing displays. The session starts with 3 papers on image sensors, including demonstrations of a back-illuminated stacked image sensor with highly parallel multi-sampling ADCs, the first 35mm-format image sensor for 8K video, and a low-power image sensor with a switchable "always-on" mode for mobile and wearable devices. The next 2 papers present a high-speed burst-mode image-acquisition system for scientific phenomena, and an event-driven motion detection system that uses in-pixel non-volatility analog memory for security applications. The latter part of the session presents recent achievements in the area of capacitive touch-sensing displays. This includes the first system where passive/active styluses and multi-fingers can simultaneously touch a 60-inch display. Another paper presents a system where touch is extended into the 3rd dimension for mobile applications. A 6b-resolution pen pressure sensor that uses a passive resonant stylus is introduced that can replace conventional costly Electro-Magnetic-Resonance-based touch systems.
Midbrain SERT in degenerative parkinsonisms: A 123I‐FP‐CIT SPECT study (2010)

SPECT imaging is widely used for the differential diagnosis of degenerative parkinsonisms by exploiting the high affinitiy of the radiotracer (123)I-FP-CIT for the dopamine transporter. Reduced levels of DAT are found in Parkinson Disease (PD), Dementia with Lewy Bodies (DLB), and Progressive Supranuclear Palsy (PSP) compared to in Essential Tremor (ET) and Healthy Controls (HC). However, the extent of the neurodegenerative process may extend beyond nigrostriatal system. We have exploited the affinity of the same radiotracer (123)I-FP-CIT for the serotonin transporter to investigate SERT levels in the midbrain of patients with PD, DLB, PSP, and ET compared to HC. Using MRI images as anatomical templates for midbrain uptake quantification, we found a mild decrease in SERT levels in PD compared to ET and HC, with marked inter-individual variability; on the other side, PSP and DLB patients displayed markedly reduced to undetectable levels of SERT, respectively. These findings show that the neurodegenerative process affects serotoninergic neurons in parkinsonisms, with much more severe involvement in DLB than in PD patients, despite the comparable loss of striatal DAT. SERT-dependent (123)I-FP-CIT uptake may allow a more comprehensive assessment of neurochemical disturbances in degenerative parkinsonisms and may have a value for differential diagnosis.
DOP46 Extended induction treatment with mirikizumab in patients with moderately to severely active ulcerative colitis: results from a Phase 2 trial (2019)

Mirikizumab (miri) is a p19-directed IL-23 antibody that has demonstrated clinical efficacy and was well-tolerated following 12 weeks of induction treatment in a Phase 2 trial in patients with ulcerative colitis (UC).1 Patients without clinical response at Week 12 had access to an open-label (OL) extended induction (EI) for an additional 12 weeks. Week-24 extended-induction results (12 weeks induction plus 12 weeks extended induction) are reported. Patients with moderately to severely active UC (Mayo score 6–12 with a minimum endoscopic subscore [ES] ≥2) were randomised 1:1:1:1 to receive intravenous (IV) placebo (pbo, N = 63), miri 50 mg (N = 63) or 200 mg (N = 62) with possibility of exposure-based (EB) dose increases, or miri 600 mg (N = 61) every 4 weeks (Q4W), with efficacy assessment at Week 12. Non-responders (NR; see Table 1 for definition) at Week 12 had access to OL miri: extended induction for an additional 12 weeks for patients who had received induction miri (miri NR) and 12 weeks miri for patients who had received induction pbo (pbo NR). The first group of patients to enter the EI arm received OL miri 600 mg IV Q4W (N = 20). After a protocol amendment, subsequent patients entering the EI arm received OL miri 1000 mg IV Q4W (N = 64). Safety and clinical outcome (see Table 1 for definitions) data were collected throughout EI, with primary clinical activity assessment at Week 24 of study. Among miri NR, 50.0% and 43.8% receiving 12 weeks of 600 mg or 1000 mg miri, respectively, achieved clinical response, 15.0% and 9.4% achieved clinical remission, 20.0% and 15.6% had ES = 0/1, and 0 and 3.0% had an ES = 0 at the end of the EI (Week 24). Among pbo NR, 58.0% and 71.9% receiving 12 weeks of 600 mg or 1000 mg miri, respectively, achieved clinical response, 25.0% and 25.0% achieved clinical remission, 25.0% and 37.5% had ES = 0/1, and 0 and 9.4% had an ES = 0 at the end of the EI (Week 24). Treatment-emergent adverse events (AEs), discontinuations due to AE, and serious AEs were similar across treatment groups during the EI. Abstract DOP046 – Table 1 An additional 12 weeks of induction treatment allowed 43.8–50.0% of induction miri NR to achieve clinical response. Patients treated with 600 mg or 1000 mg miri Q4W had few serious AEs and discontinuations due to AEs. No new safety concerns were identified during 24 weeks of induction treatment with miri.
Asset Prices in an Exchange Economy (1978)

THIS PAPER IS A THEORETICAL examination of the stochastic behavior of equilibrium asset prices in a one-good, pure exchange economy with identical consumers. The single good in this economy is (costlessly) produced in a number of different productive units; an asset is a claim to all or part of the output of one of these units. Productivity in each unit fluctuates stochastically through time, so that equilibrium asset prices will fluctuate as well. Our objective will be to understand the relationship between these exogenously determined productivity changes and market determined movements in asset prices. Most of our attention will be focused on the derivation and application of a functional equation in the vector of equilibrium asset prices, which is solved for price as a function of the physical state of the economy. This equation is a generalization of the Martingale property of stochastic price sequences, which serves in practice as the defining characteristic of market efficiency, as that term is used by Fama [7] and others. The model thus serves as a simple context for examining the conditions under which a price series' failure to possess the Martingale property can be viewed as evidence of non-competitive or irrational behavior. The analysis is conducted under the assumption that, in Fama's terms, prices fully reflect all available an hypothesis which Muth [13] had earlier termed rationality of expectations. As Muth made clear, this hypothesis (like utility maximization) is not behavioral: it does not describe the way agents think about their environment, how they learn, process information, and so forth. It is rather a property likely to be (approximately) possessed by the outcome of this unspecified process of learning and adapting. One would feel more comfortable, then, with rational expectations equilibria if these equilibria were accompanied by some form of stability theory which illuminated the forces which move an economy toward equilibrium. The present paper also offers a convenient context for discussing this issue. The conclusions of this paper with respect to the Martingale property precisely replicate those reached earlier by LeRoy (in [10] and [11]), and not surprisingly, since the economic reasoning in [10] and the present paper is the same. The
Spatio-temporally-complex concentration profiles using a tunable chaotic micromixer (2006)

The ability to present cells with stimuli that vary in space and time is key for a mechanistic understanding of dynamic processes such as cell migration, growth, adaptation, and differentiation. Microfluidic gradient devices that output multiple concentrations of a given compound exist, but changing the output generally requires a change in flow rates that can be confounding in biological measurements and/or impractical for high-throughput applications. We present chaotic mixers that generate multiple, complex concentration gradients that can be smoothly varied in time without significantly altering the flow rate.
Serum p53 antibodies in patients with oral lesions: Correlation with p53/HSP70 complexes (1997)

The functional significance of alterations in expression of tumour-suppressor gene p53 and 70-kDa heat-shock protein (HSP70) in eliciting p53-specific humoral response in oral-cancer patients is not yet known. In this study, p53 auto-antibodies were analyzed in sera from oral-cancer patients by immunoblotting and results were correlated with clinicopathological features of the patients as well as with the levels of HSP70, p53 and p53-HSP70 complexes in matched patients' tumour tissue, for determining their diagnostic/prognostic significance and relationship to survival. Circulating anti-p53 antibodies were observed in 7 of 30 cancer patients and 3 of 25 patients with pre-malignant lesions. Over-expression of p53 protein in matched oral lesions was observed in 22 of these 30 cancer patients and 14 of 25 patients with dysplastic lesions. No detectable levels of p53 protein or anti-p53 antibodies were observed in normal subjects (15 cases). Elevated levels of HSP70 were observed in 23 of these 30 oral tumours and 17 of 25 dysplastic lesions. All the anti-p53-antibody-seropositive cases showed elevated levels of p53 and HSP70 proteins, as well as formation of p53-HSP70 complexes, in matched dysplastic or malignant lesions, suggesting that these molecular alterations may be early events in oral tumorigenesis and are implicated in eliciting p53-specific humoral immune response in these patients. Anti-p53-antibody-seropositive cases showed poor prognosis and significantly decreased overall disease-free survival in comparison with the seronegative cases. Detection of circulating anti-p53 antibodies may serve as a useful non-invasive marker for identifying oral tumours having poor prognosis.
Single Subject Designs: Current Methodologies and Future Directions (2010)

Knowledge of the best uses, limitations, and quality criteria for single subject design (SSD) research has grown over the decades. High-quality SSDs provide replicable results and advance knowledge. Using modern technology, meta-analysis and systematic review methods can be applied to synthesize results of SSDs to provide best evidence on numerous important interventions (e.g., those involving assistive technology). Larger numbers of SSDs are needed.
Domain-specific keyphrase extraction (1999)

Keyphrases are an important means of document summarization, clustering, and topic search. Only a small minority of documents have author-assigned keyphrases, and manually assigning keyphrases to existing documents is very laborious. Therefore it is highly desirable to automate the keyphrase extraction process. This paper shows that a simple procedure for keyphrase extraction based on the naiveBayes learning scheme performs comparably to the state of the art. It goes on to explain how this procedure&apos;s performance can be boosted by automatically tailoring the extraction process to the particular document collection at hand. Results on a large collection of technical reports in computer science show that the quality of the extracted keyphrases improves signi#cantly when domain-speci#c information is exploited. 1 Introduction Keyphrases give a high-level description of a document&apos;s contents that is intended to make it easy for prospective readers to decide whether or no...
Providing strong 5G mobile network slice isolation for highly sensitive third-party services (2018)

Future 5G mobile networks are expected to support network slicing, i.e. multiple virtual networks running on a common infrastructure. A virtual network, called network slice, may be created to support a specific communication service type, such as massive machine-type communication, or even a specific application, for example one single Internet of Things (IoT) application. Network slices may be created by an organization like a Mobile Network Operator (MNO) and rented out to 3 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">rd</sup> -party organizations like enterprises. A prerequisite for running a highly sensitive service in a network slice is full isolation of the slice against all other users of the common network infrastructure. An industry vertical renting a slice for an Industry 4.0 application may even require isolation against the organizations providing the network infrastructure. In this paper, we introduce different novel provisioning models for 3 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">rd</sup> -party slices and discuss their isolation properties. We conclude that network slices relying solely on common infrastructure cannot meet highest isolation requirements. We therefore introduce new network architecture deployment models which include 3 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">rd</sup> -party-owned network infrastructure, and show how they can be used by 3 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">rd</sup> -parties to implement highly secure mobile communication services.
A half century of electronic fetal monitoring and bioethics: silence speaks louder than words (2017)

Bioethics abolished the prevailing Hippocratic tenet instructing physicians to make treatment decisions, replacing it with autonomy through informed consent. Informed consent allows the patient to choose treatment after options are explained by the physician. The appearance of bioethics in 1970 coincided with the introduction of electronic fetal monitoring (EFM), which evolved to become the fetal surveillance modality of choice for virtually all women in labor. Autonomy rapidly pervaded all medical procedures, but there was a clear exemption for EFM. Even today, EFM remains immune to the doctrine of informed consent despite continually mounting evidence which proves the procedure is nothing more than myth, illusion and junk science that subjects mothers and babies alike to increased risks of morbidity and mortality. And ethicists have remained utterly silent through a half century of EFM misuse. Our article explores this egregious ethical failure by reviewing EFM's lack of clinical efficacy, discussing the EFM related harm to mothers and babies, and focusing on the reasons that this obstetrical procedure eluded the revolutionary change from the Hippocratic tradition to autonomy through informed consent.
Design and Performance of a W-Band Broadband Finline Diplexer with Over 20 GHz Bandwidth (2005)

This paper describes the design and performance of a contiguous 90- to 112-GHz diplexer using the integrated finline technique. State-of-the-art results of 1.5 dB insertion losses have been achieved. There is good agreement between the experimental results and those predicted theoretically; these results demonstrate a significant technological advance of millimeter-wave multiplexer using printed circuit techniques. Results of an extremely wideband H-plane tee with a VSWR of less than 1.4 over the full W-band (75 to 110 GHz) are also presented.
The effect of embossing process conditions on the surface properties of a plasticized vinyl polymer. (2023)

Master of Science (M.S.)
Effects of knee flexion on the femoropopliteal artery: A computational study (2013)

During knee flexion, the muscles of the upper leg impose various loads on the underlying femoropopliteal artery resulting in radial compression, bending, torsion, axial extension and axial compression. Measuring the dynamic force environment of the femoropopliteal artery and quantifying its resulting deformation characteristics is an essential input to peripheral device design. The goal of this study was to create an anatomically accurate, three dimensional finite element model capable of capturing the loading conditions and deformation characteristics of the femoropopliteal artery during knee flexion. Three dimensional geometries of the muscle, bone, arterial and soft tissues of the leg were constructed from CT scan data and meshed for finite element analysis. Knee flexion was simulated and deformation characteristics of length change (axial compression), curvature, radial compression and axial twist were quantified and compared to previous experimental studies. The model predicts 8.23% shortening and an average curvature of 0.294±0.26 cm(-1) in the vessel after knee flexion, with maximum stresses of 61.17 kPa and maximum strains of 0.16%. The model created replicates known in vivo deformation characteristics seen previously in angiographic images and for the first time associates femoropopliteal artery deformation characteristics with stress and strain levels within the arterial tissue.
Psychosocial Interventions for Children and Adolescents after a Disaster: A Systematic Literature Review (1991–2015) (2016)

Mi-Sun Lee, Jun-Won Hwang, Cheol-Soon Lee, Ji-Youn Kim, Ju-Hyun Lee, Eunji Kim, Hyoung Yoon Chang, Seung-Min Bae, Jang-Ho Park, and Soo-Young Bhang. J Korean Acad Child Adolesc Psychiatry 2016;27:278-305. https://doi.org/10.5765/jkacap.2016.27.4.278
Physicochemical properties and catalytic performance of Pr2 − xSrxCoO4 ± y mixed oxides for NO reduction by CO (2006)

Using the polyglycol gel method, a series of Pr2 − x SrxCoO4 ± y (0.2 ≤ x ≤ 1.0) mixed oxides were prepared, and their catalytic activities were studied in the test reaction of NO reduction by CO. The solid-state physicochemical properties, including crystal structure, defect structure, IR spectrum, valence state of B-site ions, nonstoichiometry oxygen (y), oxygen species, and redox properties, were characterized by means of XRD, IR, TPD, TPR, XPS, and chemical analysis. The results show that all mixed oxides display a K2NiF4 structure. When x = 0.2 and 1.0, the obtained samples still have little uncertain mixed oxides; however, the mixed oxides (x = 0.4, 0.6, 0.8) all represent a single A2BO4 phase. With the increase of x, lattice parameters, unit-cell volume, and average crystalline size decrease gradually, whereas microstrain density, the concentration of Co3+, the amounts of lattice oxygen released and the concentration of oxygen vacancy increase. The catalytic activities of Pr2 − x SrxCoO4 ± y catalysts for NO reduction by CO are closely correlated with oxygen vacancy and the concentration of Co3+.
Self-Assembled Shape- and Orientation-Controlled Synthesis of Nanoscale Cu<sub>3</sub>Si Triangles, Squares, and Wires (2008)

Controlling shape and orientation is important for the synthesis of functional nanomaterials. In this work, nanoscale Cu3Si triangles, squares, and wires have been grown on Si(111), (100), and (110) substrates, respectively, through a template-free Au-nanoparticle-assisted vapor transport method. The sides of nanotriangles and nanosquares and the growth direction of the nanowires are all along Si <110>, giving rise to long-range ordering of the nanostructures. Au nanoparticles absorb Cu vapor and facilitate the rate-limited diffusion of Si, which is critical for the shape-controlled growth of Cu3Si. This bottom-up approach to synthesize shape- and orientation-controlled Cu3Si nanostructures might be applicable to the tailored growth of other materials.
Nonhomogeneous surface premelting of Au nanoparticles (2008)

A reversible nonhomogeneous surface premelting of Au nanoparticles is demonstrated through molecular dynamics simulations. With increasing temperature, liquid-like atoms first appear at some vertices and edges of surface facets, then small liquid regions grow and, at temperatures close to the particle melting temperature, most of the remaining solid-like surface atoms reside on {111} planes which are the most stable against surface premelting. The appearance of a contiguous liquid layer (complete surface premelting) is size dependent and is not observed in very small nanoparticles.
Variation of Plasma Renin Activity in Acute and Chronic Phase of Two-Kidney One-Clip Hypertension in Rabbits (1980)

In renovascular hypertension, renin-angiotensin system is considered as important to the development of hypertension. However, in the chronic phase of hypertension, peripheral plasma renin activities (PRA) have usually been found to be within normal limits, suggesting that the elevated blood pressure is maintained by a secondary non-renin mechanism. Numerous clinical reports of renal artery stenosis include patients who responded to surgery despite normal peripheral PRA. So, in the search for specific diagnostic methods in the evaluation of hypertensive patients with renal artery stenosis, the value of peripheral PRA seems questionable, whereas PRA obtained by individual renal vein catheterization appears to be more meaningful.But, it has also been pointed out that, unless the renin secretion is stimulated, falsely negative renal vein renin ratio might be obtained and possible causes have been discussed. Recently, in the Patient with surgical curable renovascular hypertension, followi ng observation has been made that renal vein PRA from the ipsilateral kidney is significantly higher than the arterial input, however, renal vein PRA from the contralateral kidney is equal to that in peripheral PRA, this evidence of suppression of renin release from the contralateral kidney seems to have additional value in predicting a response to surgery.These data seem to indicate a contributory role of fluid volume, sodium balance and other blood pressure regulating mechanisms in the maintenance of high blood pressure which at times may mask the underlying renin-angiotensin system.It is generally agreed in experimental stud y that the level of PRA was related to duration and severity of hypertension.Despite extensi ve literature on experimental renovascular hypertension, there are few previous data available on the variations in three sites of PRA of the divided renal veins and inferior caval vein in both the acute and the chronic phase of unilateral renal artery constriction in the presence of an untouched contralateral kidney (two-kidney one-clip model).
Concise Review: Mesenchymal Stem Cells for Acute Lung Injury: Role of Paracrine Soluble Factors (2011)

Morbidity and mortality have declined only modestly in patients with clinical acute lung injury (ALI) and acute respiratory distress syndrome (ARDS), despite extensive research into the pathophysiology. Current treatment remains primarily supportive with lung-protective ventilation and a fluid conservative strategy. Pharmacologic therapies that reduce the severity of lung injury in preclinical models have not yet been translated to effective clinical treatment options. Consequently, further research in translational therapies is needed. Cell-based therapy with mesenchymal stem cells (MSCs) is one attractive new therapeutic approach. MSCs have the capacity to secrete multiple paracrine factors that can regulate endothelial and epithelial permeability, decrease inflammation, enhance tissue repair, and inhibit bacterial growth. This review will focus on recent studies, which support the potential therapeutic use of MSCs in ALI/ARDS, with an emphasis on the role of paracrine soluble factors.