gebhart/patrepeval huggingface dataset:
An Overview of Japanese Manufacturing of SAW Devices (2005)

Japanese manufacturing of SAW devices is overviewed here. Japanese market of SAW devices has been limited mainly to consumer electronics such as TV and VCR. Three kinds of basic materials have been widely used. New designing method has been developed for every application, and manufacturing process including packages has been improved to make economical massproduction.
Microencapsulation of bovine spermatozoa for use in artificial insemination: a review (1993)

A technique for microencapsulation of bovine spermatozoa has been developed with minimal spermatozoal injury and thus of potential use in artificial insemination. The polymers poly-l-lysine, polyvinylamine and protamine sulfate have proven best for membranes. Encapsulation has been successful with capsules ranging in size from 0.75 to 1.5 mm, and with sperm concentrations from 45 to 180 x 10(6) cells mL-1. Successful extenders include CUE, CAPROGEN, and egg yolk-citrate-glycerol (maximum 10% v/v egg yolk for normal capsular shape). Capsule fragility (ability to rupture under ageing and physical stress) is negatively related to membrane thickness which ranges from 1.92 to 5.32 microns (depending on the concentration of polymer used) and positively related to concentration of sperm encapsulated. Heterospermic studies have shown that encapsulated sperm are capable of fertilization in vivo, but are at a disadvantage to unencapsulated sperm when cows are inseminated at conventional times. Uterine retention of inseminates is favoured by capsules having a 'sticky' membrane. Using current procedures, preliminary homospermic fertility studies indicate that sperm encapsulated with poly-l-lysine or protamine sulfate may achieve normal fertility.
New Perspectives for the Treatment of HIV Infections (1998)

The HIV replicative cycle reveals several virus-specific events that could function as targets for chemotherapeutic intervention. The compounds that are presently available as anti-HIV drugs are targeted at either the substrate binding site of the reverse transcriptase (zidovudine, didanosine, zalcitabine, stavudine, lamivudine) or a non-substrate binding site of the reverse transcriptase (nevirapine, delavirdine), or the viral protease (saquinavir, ritonavir, indinavir, nelfinavir). Remarkable clinical efficacy has been observed with combinations of different reverse transcriptase inhibitors and protease inhibitors. It may be anticipated that with the advent of newer and more efficient compounds the effectiveness of HIV inhibition could still be improved upon and the prospects for a definitive cure of the disease may be accomplished. An account with 107 references.
Effect of Solubilization of Aliphatic Hydrocarbons on Size and Shape of Rodlike C<sub>16</sub>TABr Micelles Studied by <sup>2</sup>H NMR Relaxation (1997)

Multifield 2H relaxation has been used to quantify the effect of solubilization of alkanes on the size and shape of the micelles in aqueous solutions of hexadecyltrimethylammonium bromide, C16TABr. Information about aggregate size and shape was deduced from the reorientation rate of the aggregates. The surfactant concentration was chosen so that the solutions without solubilizate contained moderately long rodlike micelles (axial ratio ∼4). It was found that the change in aggregation behavior upon solubilization is substantially different for solubilizates of similar chemical composition but different structures. Solubilization of small amounts of cyclohexane, cyclooctane, cyclodecane, trans-decalin, n-hexane, 2,3-dimethylbutane, or adamantane causes growth of the micelles. Further addition of these solubilizates (except for adamantane, which has a lower solubility limit than the other solubilizates) causes a decrease in the aggregate size. On the other hand, solubilization of n-octane, n-decane, or n-dodecane causes a decrease in aggregate size even in small amounts. It was also found that when the rodlike micelles grow due to the presence of solubilizate molecules, they grow in the axial direction at a constant radius, while the decrease in size at higher solubilizate content occurs as a shortening of the rods accompanied by an increase in radius. The differences in effects are explained by different solubilization sites within the micelle for alkanes with different molecular volume and rigidity.
Human γδ T cells as mediators of chimaeric‐receptor redirected anti‐tumour immunity (2004)

Human peripheral blood gammadelta T cells (Vgamma9(+) Vdelta2(+)) can be selectively expanded in vivo by the systemic administration of aminobisphosphonates without prior antigen priming. To assess the potential of human gammadelta T cells to serve as effector cells of specific anti-tumour immunity, we expanded peripheral blood-derived gammadelta T cells and transduced them with recombinant retrovirus encoding G(D2)- or CD19-specific chimaeric receptors. Flow cytometric analysis of T cells from four individual donors cultured in the presence of zoledronate at day 14 of culture showed selective enrichment of the gammadelta T cell population (Vgamma9(+) Vdelta2(+) CD3(+) CD4(-) CD8(-)) to 73-96% of total CD3(+) T cells. Retroviral gene transfer resulted in chimaeric receptor surface expression in 73 +/- 12% of the population. Transduced gammadelta T cells efficiently recognized antigen-expressing tumour cell targets, as demonstrated by target-specific upregulation of CD69 and secretion of interferon-alpha. Moreover, transduced gammadelta T cells efficiently and specifically lysed the antigen-expressing tumour targets. They could be efficiently expanded in vitro and maintained in culture for prolonged periods. Zoledronate-activated human gammadelta T cells expressing chimaeric receptors may thus serve as potent and specific anti-tumour effector cells. Their responsiveness to stimulation with aminobisphosphonates may enable the selective re-expansion of adoptively transferred T cells in vivo, permitting long lasting anti-tumour immune control.
Identification of antibodies on microplates (1988)

Sciendo provides publishing services and solutions to academic and professional organizations and individual authors. We publish journals, books, conference proceedings and a variety of other publications.
ChemInform Abstract: AN IMPROVED PROCEDURE FOR THE PREPARATION OF EXO‐DICYCLOPENTADIENE (1975)

Abstract Um isomerenfreies exo‐Dicyclopentadien (III) zu erhalten, wird endo‐Dicyclopentadien (I) mit 48% iger Bromwasserstoffsäure bei 75°C zu den Bromwasserstoffaddukten (II) umgesetzt.
Data fusion in robotics and machine intelligence (1992)

Data fusion and sensor integration - state-of-the-art 1990s, R.C. Luo and M.G. Gay multi-source spatial fusion using Bayesian reasoning, A. Elfes multi-sensor strategies using Dempster/Shafer belief accumulation, S.A. Hutchinson and A.C. Kak data fusion techniques using robust statistics, R. McKendall and M. Mintz recursive fusion operators - desirable properties and illustrations, Y. Chen and R.L. Kashyap distributed data fusion using Kalman filtering - a robotics application, C. Brown, et al kinematic and satistical models for data fusion using Kalman filtering, T.J. Broida and S.S. Blackman least-squares fusion of multi-sensory data, R.O. Eason and R.C. Gonzalez fusion of multi-dimensional data using regularization, M.A. Abidi geometric fusion - minimizing uncertainty ellipsoid volumes, Y. Nakamura combination of fuzzy information in the framework of possibility theory, D. Dubois and H. Prade data fusion - a neural networks implementation, T.L. Huntsberger.
Strawberry Fruit Softening: The Potential Roles of Polyuronides and Hemicelluloses (1984)

ABSTRACT Polyuronides and hemicelluloses derived from ethanol powders or cell walls of strawberry ( Fragaria × ananassa , Duch. Dover) receptacle tissue were examined to determine if these wall polymers might be involved in the softening of this fruit. Throughout maturation and ripening, total polyuronides increased on a per fruit basis although as a percentage of ethanol powder they remained constant. Gel‐filtration chromatography confirmed that polyuronide solubility was not correlated with extensive enzymic hydrolysis, an observation consistent with the fact that D‐galacturonanase (polygalacturonase) activity was not detected in strawberry fruit. The sugar composition of alkali‐soluble wall polymers showed little change throughout development. However, changes occurred in the molecular weights of these polymers during ripening.
Statistical Issues in Constructing High Resolution Physical Maps (1994)

One of the great success stories of modern molecular genetics has been the ability of biologists to isolate and characterize the genes responsible for serious inherited diseases like Huntington's disease, cystic fibrosis and myotonic dystrophy. Instrumental in these efforts has been the construction of so-called physical maps of regions of human chromosomes. A major goal of the Human Genome Project is to construct physical maps of the entire human genome. Such maps will reduce the time and expense required to isolate and study interesting chromosomal regions by many orders of magnitude. This article describes what physical maps are and how they have been used, and it outlines some of the statistical issues involved in making them.
Evaluation of dysregulation of the receptor tyrosine kinases Kit, Flt3, and Met in histiocytic sarcomas of dogs (2006)

These data suggest that dysregulation of Kit/SCF, Flt3/Flt3L, and Met/HGF signaling pathways is unlikely to occur in histiocytic sarcomas of dogs and that inhibitors of the Kit, Flt3, and Met pathways are unlikely to provide clinical benefit to dogs with histiocytic sarcomas.
An Ultraelastic Poly(ethylene oxide)/Soy Protein Film with Fully Amorphous Structure (2011)

ADVERTISEMENT RETURN TO ISSUEPREVNoteAn Ultraelastic Poly(ethylene oxide)/Soy Protein Film with Fully Amorphous StructureJianying Ji, Bin Li, and Wei-Hong Zhong*View Author Information School of Mechanical and Materials Engineering, Washington State University, Pullman, Washington 99164, United States*Tel +1 509 335 7658; fax +1 509 335 4662; e-mail [email protected]Cite this: Macromolecules 2012, 45, 1, 602–606Publication Date (Web):December 7, 2011Publication History Received20 October 2011Revised23 November 2011Published online7 December 2011Published inissue 10 January 2012https://doi.org/10.1021/ma202347vCopyright © 2011 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views1149Altmetric-Citations31LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (3 MB) Get e-AlertsSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Charge transport,Electrical properties,Ionic conductivity,Ions,Protein structure Get e-Alerts
Mifepristone inhibits MPA-and FGF2-induced mammary tumor growth but not FGF2-induced mammary hyperplasia. (2010)

We have previously demonstrated a crosstalk between fibroblast growth factor 2 (FGF2) and progestins inducing experimental breast cancer growth. The aim of the present study was to compare the effects of FGF2 and of medroxyprogesterone acetate (MPA) on the mouse mammary glands and to investigate whether the antiprogestin RU486 was able to reverse the MPA- or FGF2-induced effects on both, mammary gland and tumor growth. We demonstrate that FGF2 administered locally induced an intraductal hyperplasia that was not reverted by RU486, suggesting that FGF2-induced effects are progesterone receptor (PR)-independent. However, MPA-induced paraductal hyperplasia was reverted by RU486 and a partial agonistic effect was observed in RU486-treated glands. Using C4-HD tumors which only grow in the presence of MPA, we showed that FGF2 administered intratumorally was able to stimulate tumor growth as MPA. The histology of FGF2-treated tumors showed different degrees of gland differentiation. RU486 inhibited both, MPA or FGF2 induced tumor growth. However, only complete regression was observed in MPA-treated tumors. Our results support the hypothesis that stromal FGF2 activates PR inducing hormone independent tumor growth.
System accuracy analysis of the multiphase voltage regulator module (2004)

This paper analyzes the system accuracy of the multiphase voltage regulator module (VRM), and identifies the influential factors contributing to the system errors. PSpice Monte Carlo analysis, a more realistic statistical method of system accuracy prediction, is used to simulate the load line of the multiphase voltage regulator module for the next generation microprocessors. The Monte Carlo simulation result is compared with a worst-case analysis, a root-sum-square method, and is verified by the experimental results of a three phase synchronous buck converter.
6-<i>C</i>-(<i>E</i>-phenylethenyl)-Naringenin Suppresses Colorectal Cancer Growth by Inhibiting Cyclooxygenase-1 (2013)

Recent clinical trials raised concerns regarding the cardiovascular toxicity of selective cyclooxygenase-2 (COX-2) inhibitors and cyclooxygenase-1 (COX-1) is now being reconsidered as a target for chemoprevention. Our aims were to determine whether selective COX-1 inhibition could delay or prevent cancer development and also clarify the underlying mechanisms. Data clearly showed that COX-1 was required for maintenance of malignant characteristics of colon cancer cells or tumor promoter-induced transformation of preneoplastic cells. We also successfully applied a ligand-docking computational method to identify a novel selective COX-1 inhibitor, 6-C-(E-phenylethenyl)-naringenin (designated herein as 6CEPN). 6CEPN could bind to COX-1 and specifically inhibited its activity both in vitro and ex vivo. In colorectal cancer cells, it potently suppressed anchorage-independent growth by inhibiting COX-1 activity. 6CEPN also effectively suppressed tumor growth in a 28-day colon cancer xenograft model without any obvious systemic toxicity. Taken together, COX-1 plays a critical role in human colorectal carcinogenesis, and this specific COX-1 inhibitor merits further investigation as a potential preventive agent against colorectal cancer.
Transplantation of umbilical cord blood‐derived endothelial progenitor cells: a promising method of therapeutic revascularisation (2005)

Therapeutic neovascularisation by endothelial progenitor cells (EPCs) mediated vascular regeneration is becoming a novel option for the treatment of ischaemic diseases. Recently, human umbilical cord blood (CB) has been found to contain a large number of EPCs and transplantation of CB EPCs led to a successful salvage of the ischaemic limbs through improvement in blood perfusion, indicating the feasibility of using CB cells for therapeutic revascularisation. This review will summarise recent studies in therapeutic revascularisation using CB cells and discuss the potential clinical utilisation of CB cells in ischaemic diseases.
High Sensitivity of Refractive Index Sensor Based on Analyte-Filled Photonic Crystal Fiber With Surface Plasmon Resonance (2015)

Two kinds of novel plasmonic high sensitivity of refractive index (RI) sensors based on analyte-filled photonic crystal fiber (AF-PCF) are proposed in this paper. The metallic gold and silver is used as the surface plasmon resonance activity metal. A full-vector finite-element method is applied to analyze and investigate the sensing and coupling characteristics of this designed AF-PCF with the gold or silver layer. Phase matching between the second surface plasmon polariton and fundamental modes can be met at different wavelengths as the analyte of the RI is increased from 1.40 to 1.42. The phase-matching wavelength of the designed AF-PCF with the gold layer is shifted to the longer wavelength direction compared with that with the silver layer, and the resonance strength is much stronger. The average sensitivities of 7040 and 7017 nm/RIU in the sensing are arranged from 1.40 to 1.42 with high linearity are achieved for the designed sensors with the gold and silver layers, respectively, which are almost the same. However, the figure of merit with the silver layer is much better than that with the gold layer.
[Antenatal diagnosis of albinism fetuses by fetalscopy]. (1998)

Fetalscopy is a quick, accurate, safe method in antenatal diagnosis of heredity diseases, such as albinism.
The Type IV Pilus Assembly Complex: Biogenic Interactions among the Bundle-Forming Pilus Proteins of Enteropathogenic <i>Escherichia coli</i> (2002)

Production of type IV bundle-forming pili (BFP) by enteropathogenic Escherichia coli (EPEC) requires the protein products of 12 genes of the 14-gene bfp operon. Antisera against each of these proteins were used to demonstrate that in-frame deletion of individual genes within the operon reduces the abundance of other bfp operon-encoded proteins. This result was demonstrated not to be due to downstream polar effects of the mutations but rather was taken as evidence for protein-protein interactions and their role in the stabilization of the BFP assembly complex. These data, combined with the results of cell compartment localization studies, suggest that pilus formation requires the presence of a topographically discrete assembly complex that is composed of BFP proteins in stoichiometric amounts. The assembly complex appears to consist of an inner membrane component containing three processed, pilin-like proteins, BfpI, -J, and -K, that localize with BfpE, -L, and -A (the major pilin subunit); an outer membrane, secretin-like component, BfpB and -G; and a periplasmic component composed of BfpU. Of these, only BfpL consistently localizes with both the inner and outer membranes and thus, together with BfpU, may articulate between the Bfp proteins in the inner membrane and outer membrane compartments.
Pyrimidine derivatives and related compounds. XLVI. Thermal and photochemical transformation of 5-substituted 6-azido-1,3-dimethyluracils into fused pyrimidines such as isoxazolo(3,4-d)pyrimidines, pyrazolo(3,4-d)pyrimidines, and pyrimido(4,5-d)(1,2,3)triazine. (1983)

Thermolysis and photolysis of 6-azido-1, 3-dimethyluracils possessing certain substituents (formyl, benzoyl, hydrazonomethyl, phenyl, and benzyl groups) at the 5-position provided new methods for the preparation of fused pyrimidines. Irradiation and heating of 5-formyl-and 5-benzoyl-6-azidouracils (3 and 7) led to the formation of isoxazolo [3, 4-d] pyrimidines (4 and 8). 2-(Substituted amino) pyrazolo [3, 4-d] pyrimidines (14) were conveniently prepared by the reaction of 6-chloro-5-hydrazonomethyl-1, 3-dimethyluracils (12) with sodium azide, followed by thermolysis of the resulting 6-azides. Upon thermolysis and photolysis of 5-phenyl-and 5-benzyl-6-azidouracils (16 and 19), pyrimido [4, 5-b] indole (17) and pyrimido [4, 5-b] quinoline (10) were obtained, respectively. Cyclization of 3 using triethyl phosphite and triphenylphosphine resulted in the formation of a new ring system, pyrimido [4, 5-d] [1, 2, 3] triazine (5).
Grounding, Contingency and Transitivity (2015)

Abstract Grounding contingentism is the doctrine according to which grounds are not guaranteed to necessitate what they ground. In this paper I will argue that the most plausible version of contingentism (which I will label ‘serious contingentism’) is incompatible with the idea that the grounding relation is transitive, unless either ‘priority monism’ or ‘contrastivism’ are assumed.
Design of a Rotational Hydroelastic Actuator for a Powered Exoskeleton for Upper Limb Rehabilitation (2009)

The goal of this study was to validate the suitability of a novel rotational hydroelastic actuator (rHEA) for use in our new rehabilitation exoskeleton for the upper limbs, the Limpact. The rHEA consists of a rotational hydraulic actuator and a custom-designed symmetric torsion spring in a series-elastic configuration. For rehabilitation therapy and impairment quantification, both compliant impedance control and stiff admittance control modes are possible. In the validation experiments, the torque bandwidth of the rHEA was limited to 18 Hz for a desired 20 N m reference signal (multisine, constant spectrum) due the transport delays in the long flexible tubes between the valve and cylinder. These transport delays also required changes to existing theoretical models to better fit the models on the measured frequency response functions. The (theoretical) measurable torque resolution was better than 0.01 N m and the (validated) delivered torque resolution below 1 N m. After the validation experiments, further iterative improvements resulted in a spring design capable of a maximum output torque of 50 N m with an intrinsic stiffness of 150 N . m/rad and a slightly higher bandwidth. With the design locked, the maximum measurable isometric torque is 100 N m. In conclusion, the rHEA is suitable for upper limb rehabilitation therapy as it matches the desired performance.
A Molecular Timetable for Apical Bud Formation and Dormancy Induction in Poplar (2007)

The growth of perennial plants in the temperate zone alternates with periods of dormancy that are typically initiated during bud development in autumn. In a systems biology approach to unravel the underlying molecular program of apical bud development in poplar (Populus tremula x Populus alba), combined transcript and metabolite profiling were applied to a high-resolution time course from short-day induction to complete dormancy. Metabolite and gene expression dynamics were used to reconstruct the temporal sequence of events during bud development. Importantly, bud development could be dissected into bud formation, acclimation to dehydration and cold, and dormancy. To each of these processes, specific sets of regulatory and marker genes and metabolites are associated and provide a reference frame for future functional studies. Light, ethylene, and abscisic acid signal transduction pathways consecutively control bud development by setting, modifying, or terminating these processes. Ethylene signal transduction is positioned temporally between light and abscisic acid signals and is putatively activated by transiently low hexose pools. The timing and place of cell proliferation arrest (related to dormancy) and of the accumulation of storage compounds (related to acclimation processes) were established within the bud by electron microscopy. Finally, the identification of a large set of genes commonly expressed during the growth-to-dormancy transitions in poplar apical buds, cambium, or Arabidopsis thaliana seeds suggests parallels in the underlying molecular mechanisms in different plant organs.
The Study on the Screening of Cellulase-producing Strains and the Growth Conditions of Enzyme (2003)

Thermomonospora fusca was chosen as an original strain for screening highyield cell ulase mutants. Spora suspension of the organism was treat ment with UV for 60s and 80s alternately. Ahigh cellulase-producing mutant strain PE-211 was obtained by screening using the methods of transparent zone and shaking culture. The activity of mutant strains PE-211 was enhanced for more than one time comparing with that of the original strain. The CMCase-producing conditions of PE-211 were studied too.