gebhart/patrepeval huggingface dataset:
Design and Analysis of a Double Superimposed Chamber MEMS Micropump (2005)

The mathematical model of a double chamber pump is obtained by dividing the problem in two separate ones. The first that considers inertia force and viscous loss in relation of actuation pressure and frequency is obtained, and then a model of the nozzle/diffuser elements is introduced. The value of the flow rate obtained from the first model is then introduced in the second to determine the loss coefficients starting from geometrical properties and flow velocity. Then the loss coefficients obtained are used in the first model to obtain a new value of flow rate. These two models have been implemented in a Matlab® code that numerically reaches convergence repeating the cycle above. Using this model is possible to predict performances of the micropump only from geometrical properties and actuation parameters, without assumptions about the loss coefficients. A similar model is obtained for a single-chamber pump with geometrical dimensions equal to each chamber of the double chamber pump, and the results from both the models are then compared for equal applied actuation pressure and frequency. Results gives for our pump a max flow working frequency that is about 30% lower than the single chamber design, with the same applied pressure on the membrane, same geometry of parts and materials, and a max flow rate that is about 140% of the single chamber max flow in max flow conditions. For lower frequencies flow rate is more than twice, and maximum membrane deflection smaller up to 20% less. These results can change due to geometrical and material properties. Finally the influences of every significant geometrical property on flow rate, maximum flow frequency, loss coefficients and membrane strain are examined, and the nozzle/diffuser initial width and chamber side length are founded to be the most important dimension.
A computational mechanics avatar for the characterization and analysis of granular matter (2014)

We present a computational mechanics avatar that enables unprecedented characterization and analysis of real granular systems. We describe new developments of the avatar framework in the following areas: seamless integration of volumetric data from X-Ray Computed Tomography (XRCT) and discrete element models, and new algorithms for the representation of non-convex particles and implicit time integration. We also present an application of the avatar concept within a multi-scale framework where dilatancy is extracted directly from a real microstructure and upscaled into a continuum finite element model. We shall give an outlook on the future of the avatar concept and discuss its role in opening new avenues in multi-scale modeling and materials characterization.
Processing of three-dimensional flash lidar terrain images generating from an airborne platform (2009)

Data from the first Flight Test of the NASA Langley Flash Lidar system have been processed. Results of the analyses are presented and discussed. A digital elevation map of the test site is derived from the data, and is compared with the actual topography. The set of algorithms employed, starting from the initial data sorting, and continuing through to the final digital map classification is described. The accuracy, precision, and the spatial and angular resolution of the method are discussed.
A parallel processing method for implementing the RSA cryptosystem (1993)

Abstract Modular multiplication: R = A · B mod N (where A, B, N , and R are integers) is an essential operation used in public‐key cryptosystems such as RSA, El Gamal, and Rabin. Thus, if high‐speed modular multiplication circuits can be constructed, these cryptosystems can operate at high speeds. In this paper, we show how to construct, with a high‐speed modular multiplication circuit which employs parallel processing methods using systolic arrays, a circuit which performs modular exponentiation by repeated modular multiplication. In particular, we demonstrate its validity by using the RSA scheme as a first concrete example. Since a circuit using the method of this paper as its construction rule has simple and regular structure, it provides an optimal construction of a highspeed RSA chip in VLSI. The method is also applicable for a simple implementation of the RSA scheme with small‐sized chips. In this case, the number of chips needed by this method (the circuit size) allows the practical realization of proportionately higher speeds. Flexibility can be achieved for a change in the number of key bits by a corresponding increase or decrease in the number of chips.
Detection of IFN-γ Secretion in Blood Samples Collected Before and After Treatment of Varying Stages of Lyme Disease (2021)

The QuantiFERON ELISA reliably detected IFN-γ in blood samples from adult and adolescent patients with varying stages of Lyme disease and the response disappeared rapidly after treatment. Additional studies to more critically evaluate clinical utility as a laboratory test for diagnosis and confirmation of effective therapy are warranted.
A 4/6-Pole PSC Motor with Shared Windings (2007)

Most impeller washers in today's world market are driven by a single-speed 4-pole PSC motor. To achieve delicate washing, lower spinning speed, etc., a lower speed is often desired. A 4/6-pole PSC motor with most of the windings shared was developed by the author. As compared with the 4-pole PSC, the increase in the material usage is moderate. The newly designed 4/6-pole PSC motors are in production. It has the potential to be widely accepted by the washer industry. The paper will present the design considerations, winding distribution, connection diagram, performance, etc.
Ferrocene Catalyzed Carbon Nanotube Formation in Carbonaceous Solid (2007)

Carbon nanotubes are formed in a carbonaceous solid from thermal decomposition of various amounts of 1,4-diferrocenylbutadiyne in the presence of an excess amount of a multi(ethynyl)aromatic compound. Only a small amount of the ferrocenyl compound is needed to achieve the formation of carbon nanotubes in high yield. The method described here permits the large-scale production of carbon nanotubes in a shaped, solid configuration. The carbon nanotubes form under atmospheric pressure during the carbonization process above 500 °C in the carbonaceous solid. The Fe atoms, nanoclusters, and/or nanoparticles formed from the decomposition of the 1,4-diferrocenylbutadiyne are the key to the formation of the carbon nanotubes in the developing carbonaceous solid by reacting with the developing polycondensed aromatic ring system. The carbonaceous solids were characterized by X-ray diffraction, Raman spectroscopy, transmission electron microscopy, and scanning electron microscopy studies.
Inhibition of Human Papillomavirus DNA Replication by Small Molecule Antagonists of the E1-E2 Protein Interaction (2003)

Human papillomavirus (HPV) DNA replication is initiated by recruitment of the E1 helicase by the E2 protein to the viral origin. Screening of our corporate compound collection with an assay measuring the cooperative binding of E1 and E2 to the origin identified a class of small molecule inhibitors of the protein interaction between E1 and E2. Isothermal titration calorimetry and changes in protein fluorescence showed that the inhibitors bind to the transactivation domain of E2, the region that interacts with E1. These compounds inhibit E2 of the low risk HPV types 6 and 11 but not those of high risk HPV types or of cottontail rabbit papillomavirus. Functional evidence that the transactivation domain is the target of inhibition was obtained by swapping this domain between a sensitive (HPV11) and a resistant (cottontail rabbit papillomavirus) E2 type and by identifying an amino acid substitution, E100A, that increases inhibition by approximately 10-fold. This class of inhibitors was found to antagonize specifically the E1-E2 interaction in vivo and to inhibit HPV DNA replication in transiently transfected cells. These results highlight the potential of the E1-E2 interaction as a small molecule antiviral target.
Synthesis of 1-bromoestradiol (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of 1-bromoestradiolMark D. Hylarides, Alberto A. Leon, Fred A. Mettler Jr., and D. S. WilburCite this: J. Org. Chem. 1984, 49, 15, 2744–2745Publication Date (Print):July 1, 1984Publication History Published online1 May 2002Published inissue 1 July 1984https://pubs.acs.org/doi/10.1021/jo00189a019https://doi.org/10.1021/jo00189a019research-articleACS PublicationsRequest reuse permissionsArticle Views68Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Design of Multiplexed Coding for User Cooperation (2006)

We consider the multiplexed coding design for cooperative communications. The ideal multiplexed coding, which outperforms the superposition coding in theory, is difficult to implement with practical error-correction codes. We therefore in- troduce a partially multiplexed (PMP) coding scheme to approach the performance of fully multiplexed coding scheme. We then design the PMP coding using irregular repeat accumulate (IRA) codes. We also present a practical superposition coding scheme with two decoding methods. The outage analysis shows that all these schemes perform very close to lower cooperation bound. The simulation results demonstrate that both PMP and practical superposition block Markov coding for two-user cooperation provide significant gain over the non-cooperative system. I. INTRODUCTION Employing multiple antennas in wireless communications to achieve the transmit diversity or spatial diversity, known as the MIMO technology, has become a promising solution to combat fading channel and to provide very high data rate. Recently, cooperative communication techniques have drawn increasing interests due to the user cooperation diversity (1), (2), (3), which is another form of spatial diversity created by using a collection of distributed antennas from multiple terminals in a network. With user cooperation, the terminals share their antennas to form a virtual antenna array providing the potential of realizing spatial diversity through distributed coding and signal processing. In (4), two cooperation coding schemes are introduced, namely, multiplexed coding and superposition coding. Al- though those two schemes perform very close to lower bound of the outage probability for user cooperation, practically, these schemes are difficult to implement with binary error- correction codes. In this paper, we introduce practically im- plementable coding schemes on the multiplexed coding and the superposition coding for user coorperation in a two-user MAC. In particular, we introduce a partial multiplexed (PMP) coding scheme for the operation in low-rate region, i.e., the code rate Rc < 0.5, and propose a PMP code design method using capacity-approaching irregular repeat accumulate (IRA) code (5). The designed PMP code using IRA codes can be iteratively decoded with low decoding complexity for both the multiplexed and its component codes using the same code graph. Moreover, both the multiplexed code and its component codes have capacity approaching performance. We also pro- pose a simplified practical superposition coding scheme and implement two decoding methods for such scheme. The outage analysis shows that the designed coding schemes provide significant gain over non-cooperative MAC. Simulation results demonstrate that all the implemented coding schemes perform close to the outage probabilities and a large gain over non- 12
Functional diffusion maps (fDMs) evaluated before and after radiochemotherapy predict progression-free and overall survival in newly diagnosed glioblastoma (2012)

Functional diffusion mapping (fDM) has shown promise as a sensitive imaging biomarker for predicting survival in initial studies consisting of a small number of patients, mixed tumor grades, and before routine use of anti-angiogenic therapy. The current study tested whether fDM performed before and after radiochemotherapy could predict progression-free and overall survival in 143 patients with newly diagnosed glioblastoma from 2007 through 2010, many treated with anti-angiogenic therapy after recurrence. Diffusion and conventional MRI scans were obtained before and 4 weeks after completion of radiotherapy and concurrent temozolomide treatment. FDM was created by coregistering pre- and posttreatment apparent diffusion coefficient (ADC) maps and then performing voxel-wise subtraction. FDMs were categorized according to the degree of change in ADC in pre- and posttreatment fluid-attenuated inversion recovery (FLAIR) and contrast-enhancing regions. The volume fraction of fDM-classified increasing ADC(+), decreasing ADC(-), and change in ADC(+/-) were tested to determine whether they were predictive of survival. Both Bonferroni-corrected univariate log-rank analysis and Cox proportional hazards modeling demonstrated that patients with decreasing ADC in a large volume fraction of pretreatment FLAIR or contrast-enhancing regions were statistically more likely to progress earlier and expire sooner than in patients with a lower volume fraction. The current study supports the hypothesis that fDM is a sensitive imaging biomarker for predicting survival in glioblastoma.
A Wearable Device for Online and Long-Term ECG Monitoring (2018)

We present a prototype wearable device able to perform online and long-term monitoring of ECG signals, and detect anomalous heartbeats such as arrhythmias. Our solution is based on user-specific dictionaries which characterizes the morphology of normal heartbeats and are learned every time the device is positioned. Anomalies are detected via an optimized sparse coding procedure, which assesses the conformance of each heartbeat to the user-specific dictionary. The dictionaries are adapted during online monitoring, to track heart rate variations occurring during everyday activities. Perhaps surprisingly, dictionary adaptation can be successfully performed by transformations that are user-independent and learned from large datasets of ECG signals.
Uniform Nanoscale SiO[sub 2] Encapsulation of ZnS Phosphors for Improved Aging Properties under Low Voltage Electron Beam Excitation (2001)

A significant improvement (220%) is reported in the low voltage (2000 V) aging characteristics under cathodoluminescence (CL) excitation for ZnS phosphors coated with 1.0 wt % by the sol-gel technique. The formation of nanoscale uniform coating was confirmed by structural analysis. An improvement in chemical and thermal stability was also confirmed by chemical etching and heat-treatment of the -coated phosphors. Also, the CL aging study showed a much improved CL efficiency curve for the coated ZnS phosphors. The Auger electron spectroscopy study showed that the -coated phosphors were far more resistant to the loss of S species and to the formation of oxide dead layer. The structural, chemical, and CL characterizations demonstrated that the thin and uniform layers on ZnS phosphors served as protective layers retarding the surface-related degradation, which is critically important for the development of commercial field emission displays. © 2001 The Electrochemical Society. All rights reserved.
Genetic Immunization Generates Cellular and Humoral Immune Responses Against the Nonstructural Proteins of the Hepatitis C Virus in a Murine Model (1998)

Abstract Exposure to hepatitis C virus (HCV) is associated with a high prevalence of persistent viral infection and the development of chronic liver disease and hepatocellular carcinoma. Recovery from acute infection may depend upon the generation of broad-based cellular immune responses to viral structural and nonstructural proteins. We used the DNA-based immunization approach in BALB/c mice to determine whether the HCV nonstructural proteins NS3, NS4, and NS5 will induce Ab responses, CD4+ Th cell proliferation, and cytokine release in response to stimulation by recombinant proteins as well as generate CD8+ CTL activity both in vitro and in vivo. We found that the nonstructural proteins were particularly good immunogens and produced cellular immune responses when administered as a DNA construct. Indeed, a tumor model was established following inoculation of syngenic SP2/0 cells stably transfected with NS5. We observed protection against tumor formation and growth only in mice immunized with the NS5-encoding DNA construct, establishing the generation of significant CTL activity in vivo by this technique. The results indicate that genetic immunization may define the cellular immune response of the host to HCV nonstructural proteins and is a promising approach for vaccine development.
Making Complex Electrically Conductive Patterns on Cloth (2008)

A method for automated fabrication of flexible, electrically conductive patterns on cloth substrates has been demonstrated. Products developed using this method, or related prior methods, are instances of a technology known as 'e-textiles,' in which electrically conductive patterns ar formed in, and on, textiles. For many applications, including high-speed digital circuits, antennas, and radio frequency (RF) circuits, an e-textile method should be capable of providing high surface conductivity, tight tolerances for control of characteristic impedances, and geometrically complex conductive patterns. Unlike prior methods, the present method satisfies all three of these criteria. Typical patterns can include such circuit structures as RF transmission lines, antennas, filters, and other conductive patterns equivalent to those of conventional printed circuits. The present method overcomes the limitations of the prior methods for forming the equivalent of printed circuits on cloth. A typical fabrication process according to the present method involves selecting the appropriate conductive and non-conductive fabric layers to build the e-textile circuit. The present method uses commercially available woven conductive cloth with established surface conductivity specifications. Dielectric constant, loss tangent, and thickness are some of the parameters to be considered for the non-conductive fabric layers. The circuit design of the conductive woven fabric is secured onto a non-conductive fabric layer using sewing, embroidery, and/or adhesive means. The portion of the conductive fabric that is not part of the circuit is next cut from the desired circuit using an automated machine such as a printed-circuit-board milling machine or a laser cutting machine. Fiducials can be used to align the circuit and the cutting machine. Multilayer circuits can be built starting with the inner layer and using conductive thread to make electrical connections between layers.
Provisioning algorithms for WDM optical networks (1999)

This paper concerns connection provisioning for optical networks employing wavelength division multiplexing. A heuristic algorithm is developed and numerically studied for routing and wavelength assignment of a set of static connection requests. The algorithm runs much faster than the optimum solution of this problem. An adaptation of the algorithm is proposed to design restorable networks which can handle a specified set of failures. The proposed algorithm is based on taking all failures into consideration simultaneously, and performs better than developing independent designs for each failure.
Hordein Accumulation in Developing Barley Grains (2019)

The temporal pattern of accumulation of hordein storage proteins in developing barley grains was studied by enzyme-linked immunosorbent assay (ELISA), western blot and liquid chromatography tandem mass spectrometry (LC-MS/MS). Hordein accumulation was compared to the pattern seen for two abundant control proteins, serpin Z4 (an early accumulator) and lipid transferase protein (LTP1, a late accumulator). Hordeins were detected from 6 days post-anthesis (DPA) and peaked at 30 DPA. Changes in fresh weight indicate that desiccation begins at 20 DPA and by 37 DPA fresh weight had decreased by 35%. ELISA analysis of hordein content, expressed on a protein basis, increased to a maximum at 30 DPA followed by a 17% decrease by 37 DPA. The accumulation of 39 tryptic and 29 chymotryptic hordein peptides representing all classes of hordein was studied by LC-MS/MS. Most peptides increased to a maximum at 30 DPA, and either remained at the maximum or did not decrease significantly. Only five tryptic peptides, members of the related B1- and γ1-hordeins decreased significantly by 21-51% at 37 DPA. Thus, the concentration of some specific peptides was reduced while remaining members of the same family were not affected. The N-terminal signal region was removed by proteolysis during co-translation. In addition to a suite of previously characterized hordeins, two novel barley B-hordein isoforms mapping to wheat low molecular weight glutenins (LMW-GS-like B-hordeins), and two avenin-like proteins (ALPs) sharing homology with wheat ALPs, were identified. These identified isoforms have not previously been mapped in the barley genome. Cereal storage proteins provide significant nutritional content for human consumption and seed germination. In barley, the bulk of the storage proteins comprise the hordein family and the final hordein concentration affects the quality of baked and brewed products. It is therefore important to study the accumulation of hordeins as this knowledge may assist plant breeding for improved health outcomes (by minimizing triggering of detrimental immune responses), nutrition and food processing properties.
Path-based rules in object-oriented programming (1996)

Object-oriented programming has recently emerged as one of the most important programming paradigms. While object-oriented programming clearly owes an intellectual debt to AI, it appears to be displacing some AI techniques, such as rule-based programming, from the marketplace. This need not be so as pathbased rules---forward-chaining production rules that are restricted to follow pointers between objects---fit into the object-oriented paradigm in a clean and elegant way. The combination of path-based rules and object-oriented programming should be useful in AI applications, and in the more general problem of transferring AI techniques to the larger computer science community. To this day, forward-chaining production rules remain largely unused in mainstream object-oriented applications. One reason for this lack of use is, of course, that many production rule systems (such as most versions of OPS (Cooper &amp; Wogrin 1988), etc.) are written in LISP, and not in a major object-oriented lang...
Design of volumetric sub-THz negative refractive index metamaterial with gain (2016)

Conventional passive metamaterials always suffer from the limitation of loss and dispersion due to fundamental causality issue. Especially it becomes severe due to material loss at terahertz frequency. Our work resolves the loss problem by introducing gain device into the metamaterial structure. A passive volumetric metamaterial is firstly designed on the quartz substrate. A negative resistance is inserted into the wire of the structure to provide the gain. We have identified resonant tunneling diodes that work up into THz frequency and shown in simulation that simultaneous negative index and gain can be obtained.