gebhart/patrepeval huggingface dataset:
The antimicrobial peptide SAAP-148 combats drug-resistant bacteria and biofilms (2018)

Development of novel antimicrobial agents is a top priority in the fight against multidrug-resistant (MDR) and persistent bacteria. We developed a panel of synthetic antimicrobial and antibiofilm peptides (SAAPs) with enhanced antimicrobial activities compared to the parent peptide, human antimicrobial peptide LL-37. Our lead peptide SAAP-148 was more efficient in killing bacteria under physiological conditions in vitro than many known preclinical- and clinical-phase antimicrobial peptides. SAAP-148 killed MDR pathogens without inducing resistance, prevented biofilm formation, and eliminated established biofilms and persister cells. A single 4-hour treatment with hypromellose ointment containing SAAP-148 completely eradicated acute and established, biofilm-associated infections with methicillin-resistant <i>Staphylococcus aureus</i> and MDR <i>Acinetobacter baumannii</i> from wounded ex vivo human skin and murine skin in vivo. Together, these data demonstrate that SAAP-148 is a promising drug candidate in the battle against antibiotic-resistant bacteria that pose a great threat to human health.
FACTORS AFFECTING THE REGENERATION OF PEPPER (CAPSICUM ANNUUM L.) (1990)

Several growth hormone combinations and silver nitrate concentrations were examined for their effect on regeneration of different pepper genotypes. Primary leaf explants from in vitro seedlings were cultured on a revised Murashige and Skoog medium supplemented with auxin, cytokinin and 1.6% glucose. Combinations of different concentrations of indole-3-acetic acid (IAA), 0-5 mg/l, and 6-benzylaminopurine (BAP), 0-5 mg/l, were tested to determine the most effective medium for shoot primordium formation. Experiments with IAA and BAP did not result in a specific growth hormone combination appropriate for regeneration of all genotypes tested. Of the silver nitrate concentrations tested, 10 mg/l resulted in the best shoot and leaf differentiation and reduced callus formation. Differences in organogenic response of individual genotypes were evaluated on a single regeneration medium. Whole plants were regenerated from 11 of 63 genotypes examined. Based on these experiments, a reproducible regeneration system for pepper was developed with a total of 500 plants regenerated to date.
Palladium-Catalyzed N-Arylation of 2-Aminothiazoles (2012)

A method for the Pd-catalyzed coupling of 2-aminothiazole derivatives with aryl bromides and triflates is described. Significantly, for this class of nucleophiles, the coupling exhibits a broad substrate scope and proceeds with a reasonable catalyst loading. Furthermore, an interesting effect of acetic acid as an additive is uncovered that facilitates catalyst activation.
A Hardware Scheduler Based on Task Queues for FPGA-Based Embedded Real-Time Systems (2014)

A hardware scheduler is developed to improve real-time performance of soft-core processor based computing systems. A hardware scheduler typically accelerates system performance at the cost of increased hardware resources, inflexibility and integration difficulty. However, the reprogrammability of FPGA-based systems removes the problems of inflexibility and integration difficulty. This paper introduces a new task-queue architecture to better support practical task controls and maintain good resource scaling. The scheduler can be configured to support various algorithms such as time sliced priority scheduling, Earliest Deadline First and Least Slack Time. The hardware scheduler reduces scheduling overhead by more than 1,000 clock cycles and raises the system utilization bound by a maximum 19.2 percent. Scheduling jitter is reduced from hundreds of clock cycles in software to just two or three cycles for most operations. The additional resource cost is no more than 17 percent of a typical softcore system for a small scale embedded application.
How to manage knowledge transfer (2007)

Developing, retaining and sharing knowledge effectively is a major challenge for all businesses. Ensuring that employees have access to the information they need has a critical impact on their effectiveness and, ultimately, the performance of the organization as a whole.
Misregulation of human sortilin splicing leads to the generation of a nonfunctional progranulin receptor (2012)

Sortilin 1 regulates the levels of brain progranulin (PGRN), a neurotrophic growth factor that, when deficient, is linked to cases of frontotemporal lobar degeneration with TAR DNA-binding protein-43 (TDP-43)-positive inclusions (FTLD-TDP). We identified a specific splicing enhancer element that regulates the inclusion of a sortilin exon cassette (termed Ex17b) not normally present in the mature sortilin mRNA. This enhancer element is consistently present in sortilin RNA of mice and other species but absent in primates, which carry a premature stop codon within the Ex17b sequence. In the absence of TDP-43, which acts as a regulatory inhibitor, Ex17b is included in the sortilin mRNA. In humans, in contrast to mice, the inclusion of Ex17b in sortilin mRNA generates a truncated, nonfunctional, extracellularly released protein that binds to but does not internalize PGRN, essentially acting as a decoy receptor. Based on these results, we propose a potential mechanism linking misregulation of sortilin splicing with altered PGRN metabolism.
Assessment and classification of line overload risk in power systems considering different types of severity functions (2010)

Power system security assessment based on the concept of risk is required in the current power environment. In risk based security assessment, the likelihood and severity of security violation are the two main factors that determine the security level of a power system. To evaluate likelihood of security violation, the probability technique based on Poisson probability distribution function is adopted. Severity function signifies the extent of security violation. Two types of severity functions, namely the continuous and percentage of violation severity functions are considered in this study. This paper presents the assessment of risk of line overload at various loading condition using a risk index. A risk classification technique is also proposed so as to provide a qualitative interpretation of the risk index value by classifying the risk as low, medium and high degree of risk. This paper presents the implementation of line overload security assessment on the IEEE 24 bus test system and practical interconnection power system so as to investigate the effect of severity functions on risk classification in risk assessment. Results are presented in terms of risk index curves.
Streptococci and <i>Pasteurella</i> spp. associated with disease of the equine lower respiratory tract (1993)

The likelihood of finding evidence of inflammation in 551 tracheal washes collected endoscopically from 278 Thoroughbred racehorses increased with the number of bacterial colony forming units (cfu) per ml of wash (P < 0.001). The aerobic bacteria Streptococcus zooepidemicus, Pasteurella/Actinobacillus-like species and Streptococcus pneumoniae were significantly associated with lower airway inflammation whereas coagulase-negative Staphylococcus spp., alpha-haemolytic Streptococcus spp., Acinetobacter spp., Bacillus spp., Escherichia coli, Pseudomonas aeruginosa, non-haemolytic Streptococcus spp. and Enterobacteriaceae were not; Bordetella bronchiseptica was not isolated. Lower airway inflammation was particularly associated with bacteria in horses < or = 3 years of age. S. zooepidemicus, S. pneumoniae and Pasteurella/Actinobacillus-like species were isolated from 167 of 551 washes, either alone or in combination.
New Mechanism of X-Ray Radiation from a Relativistic Charged Particle in a Dielectric Random Medium (2001)

Based on the diffusional scattering of pseudophotons, we propose a new mechanism of x-ray radiation from a relativistic charged particle moving in a system consisting of microspheres distributed randomly in a dielectric material. The mechanism leads to a stronger dependence of radiation intensity on the particle energy, gamma = E/mc(2), than that predicted by the transition radiation, and explains recent experimental data from a detector which contains randomly distributed superconducting granules.
All together now (1998)

The synchronised jacking of coupled rail vehicles is an exacting problem in distributed control. In this paper, the author describes how the LonWorks protocol took the strain out of train lifting.
An exact probability model for finite hash tables (2003)

The author presents an exact probability model for finite hash tables and applies the model to solve a few problems in the analysis of hashing techniques. The model enables exact computation of table sufficiency index, a parameter useful in the design of small hash tables. The author also presents an exact analysis of the expected length of the longest probe sequence in hashing with separate chaining, and successful search length in infinite uniform hashing giving explicit expressions. It appears that the model can be extended to analyze other hashing schemes such as bounded disorder index method, and to problems in robust data structures, etc.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A low-power, high-sensitivity micromachined optical magnetometer (2012)

We demonstrate an optical magnetometer based on a microfabricated 87Rb vapor cell in a micromachined silicon sensor head. The alkali atom density in the vapor cell is increased by heating the cell with light brought to the sensor through an optical fiber, and absorbed by colored filters attached to the cell windows. A second fiber-optically coupled beam optically pumps and interrogates the atoms. The magnetometer operates on 140 mW of heating power and achieves a sensitivity below 20 fT/√Hz throughout most of the frequency band from 15 Hz to 100 Hz. Such a sensor can measure magnetic fields from the human heart and brain.
Measurement of quality of life in patients with lung cancer in multicenter trials of new therapies. Psychometric assessment of the lung cancer symptom scale (1994)

These psychometric properties demonstrate that the LCSS patient and observer scales are feasible, reliable, and valid quality of life measures that are ready for research and clinical use with lung cancer populations.
One Step Ahead: Short-Term Wind Power Forecasting and Intelligent Predictive Control Based on Data Analytics (2012)

The intelligent integration of wind power into the existing electricity supply system will be an important factor in the future energy supply in many countries. Wind power generation has characteristics that differ from those of conventional power generation. It is weather dependent in that it relies on wind availability. With the increasing amount of intermittent wind power generation, power systems encounter more and more short-term, unpredicted power variations. In the power system, supply and demand must be equal at all times. Thus, as levels of wind penetration into the electricity system increase, new methods of balancing supply and demand are necessary.
Speed Estimation and Abnormality Detection from Surveillance Cameras (2018)

Motivated by the increasing industry trends towards autonomous driving, vehicles, and transportation we focus on developing a traffic analysis framework for the automatic exploitation of a large pool of available data relative to traffic applications. We propose a cooperative detection and tracking algorithm for the retrieval of vehicle trajectories in video surveillance footage based on deep CNN features that is ultimately used for two separate traffic analysis modalities: (a) vehicle speed estimation based on a state of the art fully automatic camera calibration algorithm and (b) the detection of possibly abnormal events in the scene using robust optical flow descriptors of the detected vehicles and Fisher vector representations of spatiotemporal visual volumes. Finally we measure the performance of our proposed methods in the NVIDIA AI CITY challenge evaluation dataset.
The MAP kinase signal transduction pathway is activated by the endogenous cannabinoid anandamide (1995)

Anandamide is an endogenous ligand for delta 9-tetrahydrocannabinol (THC) receptors. Incubation of cultured cells with anandamide or THC causes increased arachidonic acid release and eicosanoid biosynthesis. Here we demonstrate that the MAP kinase signal transduction pathway contributes to this response. Treatment of WI-38 fibroblasts with anandamide causes increased MAP kinase activity and increased phosphorylation of the arachidonate-specific cytoplasmic phospholipase A2 (cPLA2). Significantly, MAP kinase phosphorylates and activates cPLA2 [Lin, et al., Cell, 72 (1993) 269-278]. The MAP kinase signal transduction pathway may therefore mediate the effects of anadamide on cPLA2 activation and arachidonic acid release.
Inclusion Compounds of Tetrakis(4-nitrophenyl)methane:  C−H···O Networks, Pseudopolymorphism, and Structural Transformations (2001)

Tetrakis(4-nitrophenyl)methane is a new host material with considerable structural adaptability over a range of solvents. The crystal structures of 14 of these solvates have been determined and classified into three groups. The diamondoid group, wherein the host molecules form a 2-fold interpenetrated diamondoid network structure, is unprecedented in that network connections are made exclusively with weak C-H...O and pi...pi interactions. This group consists of the solvates of THF, dioxane, nitrobenzene, 4-bromoanisole, anisole, phenetole, p-xylene, and chlorobenzene. The rhombohedral group, which is characterized by specific host.guest interactions of the C-H...O and halogen...O2N type, consists of the solvates of CHCl3 and CHBr3 and somewhat surprisingly DMF, which shows an unusual 3-fold disorder mimicking in part the shape and size of the haloform molecules though not their orientation. The third group comprises solvent-rich solvates of the host with mesitylene, collidine, and o-xylene with quite different crystal structures. The THF solvate was found to lose solvent over limited temperature ranges transforming reversibly from the diamondoid structure to the rhombohedral structure. A mechanism for this process is outlined. Material from which solvent has been removed by heating was also found to resolvate upon soaking in appropriate solvents. In summary, the title compound forms a host network that is partially robust and in part flexible. It is possible that this fluxional nature of the host network derives from the weakness of the connecting interactions.
Four Different Crystals Derived from a Novel Yellow Pyrazolyl Azo Pigment (2011)

Four different crystals are presented in the present article that are derived from a novel yellow pyrazolyl azo pigment used for ink jet inks. This compound exhibits a good pigmentary performance in light and heat stability but rather poor in solvent fastness. X-ray structure analysis has been carried out in order to improve the present drawback from the structural point of view. The authors have unexpectedly isolated two kinds of five-coordinate bisazo Na complexes of the cis form (space group: C2/c). The formation of the Na complex is found to be caused by NaNO2 used for the preparation of diazo components. Then, the authors tried to eliminate the sodium atom from the Na complex using hydrochloric acid in an attempt to develop a better pigment that assumes a trans configuration. The present Na-free compound in the trans form is found to crystallize in space group P-1 and is characterized by good solvent fastness in addition to the light and heat stability of the original title compound.
The Design of 25KV High-Frequency High-Voltage Power Supply (2014)

In this paper, a HV and HF switch power supply was designed, which was controlled through a single chip microcomputer, also the MOSFET was used as the switch power tube. The PWM (pulse width modulation) technique and half-bridge inverter topology have been used to invert AC into the DC that can be adjust from 0V~25KV and the operating frequency is 35KHz, Through the simulation with the Saber software and practical use, the feasibility of the scheme and the correctness of the design have been verified.
High Performance RTM Using Massive Domain Partitioning (2011)

We demonstrate dramatic performance improvements for 3D finite difference RTM using domain partitioning over thousands of compute nodes, processing a shot for a 512x512x512 models with about 3000 time steps in under 30 seconds. We have tested this methodology on velocity models of up to 2048x2048x2048 elements in size. In addition to performance advantages, the demonstrated method benefits from substantially easier programmability because it runs on a homogenous supercomputer using standard C and MPI. It therefore is much easier to maintain, port, tune and extend to novel algorithms codes developed for heterogenous systems such as CPU+GPUs. This approach has a high affinity for existing methods, such as reservoir modeling, which are already processed today using domain partitioning and therefore makes merging seismic imaging and reservoir modeling on a single system much easier. And finally, since this methods runs entire velocity models instead of subsets for each shot, it can be easily extended to perform multisource RTM, leading to further performance benefits.
Bounds on the Spectral Norm and the Nuclear Norm of a Tensor Based on Tensor Partitions (2016)

It is known that computing the spectral norm and the nuclear norm of a tensor is NP-hard in general. In this paper, we provide neat bounds for the spectral norm and the nuclear norm of a tensor based on tensor partitions. The spectral norm (respectively, the nuclear norm) can be lower and upper bounded by manipulating the spectral norms (respectively, the nuclear norms) of its subtensors. The bounds are sharp in general. When a tensor is partitioned into its matrix slices, our inequalities provide polynomial-time worst-case approximation bounds for computing the spectral norm and the nuclear norm of the tensor.
Primary Cementing Improvement by Casing Vibration During Cement Curing Time (1988)

Summary Vibration of casing to improve primary cementing was investigated in the laboratory and in a 200-ft [60-m] deep test well. The effect of vibration is to decrease or to eliminate gel strength of the cement slurry as it is curing. The slurry then flows downward to compensate for shrinkage and re-establishes the hydrostatic head of the cement. This method can prevent pore-fluid entry into the annulus before the cement cures and can increase the radial stress at the interface between the formation and the cured cement.
Mannosidosis of Angus calves. (1979)

Mannosidosis, an inherited lysosomal storage disease, was diagnosed in two purebred Angus calves in the United States. Calf 1 was 5 months old and calf 2 was 7 months old when they were necropsied. Both calves had a history of progressive incoordination and ataxia. Gross postmortem findings included moderate hydrocephalus. Histologic examination revealed intracytoplasmic vacuolation of neurons throughout spinal cord and brain as well as in exocrine pancreatic cells, reticuloendothelial cells of the liver, and medullary sinusoids of lymph nodes. Biochemical study of 61 blood samples from the first calf's herd revealed bimodal distribution of enzyme activity for mannosidase. Two populations could be distinguished in that herd, those with normal mannosidase activity and those heterozygous for the disease.
A Review of Detection and Removal of Raindrops in Automotive Vision Systems (2021)

Research on the effect of adverse weather conditions on the performance of vision-based algorithms for automotive tasks has had significant interest. It is generally accepted that adverse weather conditions reduce the quality of captured images and have a detrimental effect on the performance of algorithms that rely on these images. Rain is a common and significant source of image quality degradation. Adherent rain on a vehicle's windshield in the camera's field of view causes distortion that affects a wide range of essential automotive perception tasks, such as object recognition, traffic sign recognition, localization, mapping, and other advanced driver assist systems (ADAS) and self-driving features. As rain is a common occurrence and as these systems are safety-critical, algorithm reliability in the presence of rain and potential countermeasures must be well understood. This survey paper describes the main techniques for detecting and removing adherent raindrops from images that accumulate on the protective cover of cameras.
An assessment of the state-of-the-art 0.5 μm bulk CMOS technology for RF applications (2002)

We demonstrate that, given the appropriate layout geometry, state-of-the-art, salicided n-MOSFETs with 0.5 /spl mu/M drawn gates exhibit similar g/sub m/ (160 mS/mm), f/sub T/ (20 GHz), f/sub MAX/ (37 GHz), and F/sub MIN/ (1.9 dB @ 3.4 GHz) as the more costly, metal-reinforced SOI or SOS devices of identical gate length. The record f/sub MAX/ value for 0.5 /spl mu/m bulk CMOS is comparable to that of self-aligned, double-polysilicon BJTs.
Distortions from curved flow in magnetic resonance imaging (1993)

We present an analysis of how vessel curvature can create distortions in magnetic resonance images of flowing blood. Steady flow in curved vessels produces distortions of the vessel shape and intensity variations in the image due to motion during the interval between phase encoding or slice selection and the echo center. Even with steady flow, vessel curvature produces motion moments higher than velocity (acceleration, etc.), but use of a first order oblique flow compensated phase encoding gradient waveform reduced the distortion in the image. Numerical calculations of image distortions based on simple flow models are in good agreement with experimental results in a phantom.
Abnormal Access Request Detection based Secure Storage Area Network System (2011)

In order to ensure security of the enormous data stored in the storage area network system, current secure technology need large time and space consumption and extra storage space. The artificial immune algorithm can efficiently detect abnormal data. In order to keep high I/O performance of storage area network system, we use the artificial immune algorithm to detect the abnormal access request of the storage area network system, and we implement the secure storage area network system named ADSSAN. We present the structure of the metadata server with the central abnormal access request detection module, the storage device with the associate abnormal access request detection module and the secure storage area network system. The definitions of main elements are given. By analyzing the feature of the storage area network system, the master-slave artificial immune algorithm is presented. The central abnormal access request detection module generates all detectors and distributes part of detectors to the associate abnormal access request detection module in the storage servers. Then the distributed strategy of artificial immune algorithm can be used to reduce the time and space consumption of generating detectors and improve performance of abnormal access request detection. The prototype of abnormal access request detection module is implemented and tested, the result shows that the master-slave artificial immune algorithm can accurately detect abnormal access request with low time and space overhead. At last, the prototype of secure storage area network system is implemented on Lustre and evaluated its I/O performance. The result shows that the central and associate abnormal access request detection module can efficiently check out abnormal access request, and the prototype of secure storage area network system can keep high I/O performance.