gebhart/patrepeval huggingface dataset:
ScatterClipse: A Model-Driven Tool-Chain for Developing, Testing, and Prototyping Wireless Sensor Networks (2008)

ScatterClipse is a generative plugin-oriented tool-chain for the model-driven development of the applications running on the sensor boards of our WSN-platform ScatterWeb. The goal is the furthermost automated and standardized generation of software system families for the ScatterWeb sensor boards. The ScatterClipse's novel approach lies in the accomplishment of the integration of visual automated application debugging and WSN-management features in the model-driven software development process of the deployed sensor boards. Furthermore the just-in-time model validation makes a large contribution towards robustness by discovering certain bugs early on, which, if manually implemented, would only be discovered very late in the process. The plugin-oriented open architecture eases the appropriate enhancement of our opensource tool-chain in response to newly arisen questions regarding WSN.
High Glucose Increases Angiopoietin-2 Transcription in Microvascular Endothelial Cells through Methylglyoxal Modification of mSin3A (2007)

Methylglyoxal is a highly reactive dicarbonyl degradation product formed from triose phosphates during glycolysis. Methylglyoxal forms stable adducts primarily with arginine residues of intracellular proteins. The biologic role of this covalent modification in regulating cell function is not known. Here we report that in mouse kidney endothelial cells, high glucose causes increased methylglyoxal modification of the corepressor mSin3A. Methylglyoxal modification of mSin3A results in increased recruitment of O-GlcNAc-transferase, with consequent increased modification of Sp3 by O-linked N-acetylglucosamine. This modification of Sp3 causes decreased binding to a glucose-responsive GC-box in the angiopoietin-2 (Ang-2) promoter, resulting in increased Ang-2 expression. Increased Ang-2 expression induced by high glucose increased expression of intracellular adhesion molecule 1 and vascular cell adhesion molecule 1 in cells and in kidneys from diabetic mice and sensitized microvascular endothelial cells to the proinflammatory effects of tumor necrosis factor alpha. This novel mechanism for regulating gene expression may play a role in the pathobiology of diabetic vascular disease.
Reflective mirrors: Perspective-taking in autoscopic phenomena (2002)

Spatial perspective-taking should be more thoroughly assessed in patients reporting autoscopic phenomena. By elucidating the interactions between spatial phenomenology and psychological function, we may gain important insights into the relationships between the self, its body, and phenomenal space.
Hybrid solid state drives for improved performance and enhanced lifetime (2013)

As the market becomes more competitive, SSD manufacturers are moving from SLC (Single-Level Cell) to MLC (Multi-Level Cell) flash memory chips that store two bits per cell as building blocks for SSDs. Recently, TLC chips, which store three bits per cell, is being considered as a viable solution due to their low cost. However, performance and lifetime of TLC chips are considerably limited and thus, pure TLC-based SSDs may not be viable as a general storage device. In this paper, we propose a hybrid SSD solution, namely HySSD, where SLC and TLC chips are used together to form an SSD solution performing in par with SLC-based products. Based on an analytical model, we propose a near optimal data distribution scheme that distributes data among the SLC and TLC chips for a given workload such that performance or lifetime may be optimized. Experiments with two types of SSDs both based on DiskSim with SSD Extension show that the analytic model approach can dynamically adjust data distribution as workloads evolve to enhance performance or lifetime.
Activity based video indexing and search (2010)

We describe a method for searching videos in large video databases based on the activity contents present in the videos.
Being able to search videos based on the contents (such as human activities) has many applications such as security,
surveillance, and other commercial applications such as on-line video search. Conventional video content-based retrieval
(CBR) systems are either feature based or semantics based, with the former trying to model the dynamics video contents
using the statistics of image features, and the latter relying on automated scene understanding of the video contents.
Neither approach has been successful. Our approach is inspired by the success of visual vocabulary of Video Google
by Sivic and Zisserman, and the work of Nister and Stewenius who showed that building a visual vocabulary tree can
improve the performance in both scalability and retrieval accuracy for 2-D images. We apply visual vocabulary and
vocabulary tree approach to spatio-temporal video descriptors for video indexing, and take advantage of the
discrimination power of these descriptors as well as the scalability of vocabulary tree for indexing. Furthermore, this
approach does not rely on any model-based activity recognition. In fact, training of the vocabulary tree is done off-line
using unlabeled data with unsupervised learning. Therefore the approach is widely applicable. Experimental results using
standard human activity recognition videos will be presented that demonstrate the feasibility of this approach.
Early transcriptional events in cell growth (1990)

How eucaryotic cells respond to growth signals is a topic of considerable interest. Though much attention has focused on second messenger pathways, in recent years, progress has been made on elucidating the transcriptional events that lie more distally in the signal transduction process. Indeed, mitogens regulate the induction of several genes without the need for de novo protein synthesis. A subset of these so-called cellular immediate-early genes encode transcription factors. This review focuses on the early growth response group of zinc finger transcriptional factors. These genes are also induced by diverse agents in contexts outside of cell growth. Thus, their characterization should provide important insights into how cellular responses to diverse extracellular signals are mediated.
Low Complexity Turbo Equalization for High Data Rate Wireless Communications (2006)

Soft interference cancellers (SICs) have been proposed in the literature as a means for reducing the computational complexity of the so-called turbo equalization receiver architecture. Soft-input-soft output (SISO) equalization algorithms based on linear filters have a tremendous complexity advantage over trellis-diagram-based SISO equalizers, especially for high-order modulations and long-delay spread frequency selective channels. In this paper, we modify the way in which the SIC incorporates soft information. In existing literature the input to the cancellation filter is the expectation of the symbols based solely on the apriori probabilities coming from the decoder, whereas here we propose to use the conditional expectation of those symbols, given both the apriori probabilities and the received sequence. This modification results in performance gains at the expense of increased computational complexity, as compared to previous SIC-based schemes. However, by introducing an approximation to the aforementioned algorithm a linear complexity SISO equalizer can be derived. Simulation results for an 8-PSK constellation and hostile radio channels have shown the effectiveness of the proposed algorithms in mitigating the intersymbol interference (ISI).
Bacteriology of cheese III. Some factors affecting the ripening of Blue (Roquefort type) cheese (2017)

BIue cheese (roquefort type) represents a cheese type of considerable commercial importance in the United States. It is not only consumed in the natural condition but is also used in making various products, such as cheese spreads, salad dressing, etc. Much of the blue cheese used in the United States is imported from various European countries. Although this type of cheese has been made in the United States from cows' milk for some time, the industry has not developed to any extent. In the various attempts to expand the blue cheese industry, American manufacturers have met with a number of difficulties. These include (a) the failure of the cheese to develop enough of the characteristic flavor in a reasonable length of time, (b) the failure of the mold to develop properly in the cheese, (c) the lack of uniformity in successive · lots of cheese, (d) the yellow color of the cheese, especially when made during the period of luxuriant pastures and (e) the relatively high cost of manufacture as compared to that in certain other countries.
A Critical Analysis of the Use of High-Speed Film to Determine Maximum Accelerations of Fish (1989)

ABSTRACT High-speed cinematography is often employed in studies on fish swimming, particularly where performance is estimated (e.g. Wardle, 1975; Eaton et al. 1977; Webb, 1978b; Dorn et al. 1979; Videler, 1981). One commonly reported aspect of performance is the acceleration of fish during fast-starts (bursts of swimming from a standing start; e.g. Weihs, 1973; Webb, 1975, 1976, 1977, 1978a,b, 1982, 1983, 1986; Rand & Lauder, 1981). The present study is a critical examination of the use of cinematography to estimate the maximum acceleration of fish during fast-starts.
Hybrid energy storage of battery-type nickel hydroxide and supercapacitor-type graphene: redox additive and charge storage mechanism (2017)

Charge storage mechanism by<italic>in situ</italic>X-ray absorption spectroscopy.
The preclinical development of MedisorbÂ® Naltrexone, a once a month long-acting injection, for the treatment of alcohol dependence (2005)

Oral naltrexone, a nonselective opioid antagonist, is approved for the treatment of alcohol and opioid dependence. However, the efficacy of oral naltrexone is limited by poor patient compliance. To overcome this limitation, attempts have been made to develop an injectable extended-release formulation of naltrexone, including encapsulation into biodegradable polymer microspheres (e.g. Medisorb Naltrexone, Vivitrex (naltrexone long acting injection)). In 1980, NIDA established development goals that they considered optimal for an extended-release formulation. At Alkermes, different formulations were tested with in vitro assays and in vivo models to select a lead formulation. Pharmacokinetic studies in rats confirmed that the principle formulation produced stable, pharmacologically relevant plasma levels of naltrexone for approximately one month following a single injection. The pharmacodynamic effects (antagonism of morphine analgesia) of extended-release naltrexone corresponded well with the pharmacokinetic profile from the same animals. While brain mu-opioid receptor density was found to increase over time in these rats, it did not appear to affect the ability of naltrexone to suppress morphine analgesia. Finally the pharmacokinetic profile of extended-release naltrexone in monkeys confirmed long duration of elevated plasma concentrations of naltrexone. Both naltrexone and the PLG polymer matrix in which it is encapsulated are well tolerated. Clinical trials of Vivitrex are currently ongoing in alcohol dependent patients.
What is the potential for overdiagnosis of heparin‐induced thrombocytopenia? (2007)

Heparin-induced thrombocytopenia (HIT) is caused by platelet-activating antibodies that recognize platelet factor 4//heparin (PF4/H) complexes. According to the "iceberg model," only a subset of anti-PF4/heparin antibodies of IgG class evincing strong platelet-activating properties cause clinical HIT. Since many centers rely predominantly on an anti-PF4/polyanion enzyme-immunoassay (EIA) to diagnose HIT, we estimated the potential for overdiagnosis when only this single test is available. We examined a database of 100 patients in whom the probability of HIT had been estimated using a clinical scoring system (4Ts), and where patients underwent systematic testing for HIT antibodies using three assays: the platelet serotonin release assay (SRA), an "in-house" EIA that detects IgG anti-PF4/heparin antibodies (EIA-IgG), and a commercial EIA that detects anti-PF4/polyanion antibodies of all three immunoglobulin classes (EIA-GTI). Whereas 16 of 100 patients fulfilled a "classic" definition of HIT (intermediate/high probability plus strong platelet-activating anti-PF4/heparin IgG antibodies), an additional 16 patients fulfilled a "liberal" definition in which any investigated patient (irrespective of the pretest probability) who had a positive EIA-GTI was considered to have HIT. The clinical features of these 16 additional patients--including generally weak antibodies and low risk for thrombosis--suggest underlying non-HIT explanations for thrombocytopenia. Patients with a positive SRA generally corresponded to those with intermediate or high pretest probability of HIT who also had strong EIA-GTI reactivity (>1.20 OD units). We conclude there is the potential to overdiagnose HIT by approximately 100% if any positive EIA is considered to "confirm" the diagnosis of HIT irrespective of the clinical scenario.
Analysis of a Biologically-Inspired System for Real-time Object Recognition (2005)

We present a biologically-inspired system for real-time, feed-forward object recognition in cluttered scenes. Our system utilizes a vocabulary of very sparse features that are shared between and within different object models. To detect objects in a novel scene, these features are located in the image, and each detected feature votes for all objects that are consistent with its presence. Due to the sharing of features between object models our approach is more scalable to large object databases than traditional methods. To demonstrate the utility of this approach, we train our system to recognize any of 50 objects in everyday cluttered scenes with substantial occlusion. Without further optimization we also demonstrate near-perfect recognition on a standard 3-D recognition problem. Our system has an interpretation as a sparsely connected feed-forward neural network, making it a viable model for fast, feed-forward object recognition in the primate visual system.
(p,n) reaction at intermediate energy. [100 to 200 MeV] (1979)

The use of the (p,n) reaction in exploring effective interactions is reviewed. Some recent data on self-conjugate nuclei taken at the Indiana University Cyclotron Facility (IUCF) are presented, and the differences between low- and high-energy data are emphasized. Experimental problems and techniques used are briefly described. It is concluded that forward-angle (p,n) spectra at energies greater than 100 MeV are dominated by Gamow-Teller (GT) transitions, while Fermi transitions (IAS transitions) dominate near 45 MeV. Prominent GT transitions are expected from a pion-exchange interaction, and it is expected that OPEP is the dominant component of the interaction in the energy range of 100 to 200 MeV. 27 figures, 2 tables.
Initiators, Free‐Radical (2002)

Abstract Most commercial free‐radical applications employ initiators such as peroxides and azo compounds. Lesser amounts of carbon–carbon initiators and photoinitiators and high energy ionizing radiation are also used commercially to generate free radicals. The chemical initiators are substances possessing labile oxygen–oxygen, carbon–nitrogen, or carbon–carbon covalent bonds that under certain thermal, chemical, or photochemical conditions undergo homolytic scission of the labile bond to produce free radicals. The free radicals produced are useful in many industrial chain reactions, eg, halogenations, additions to carbon–carbon double bonds, polymerizations of vinyl monomers, grafting reactions, curing of rubbers and unsaturated polymers, cross‐linking of polyolefins, modification of polyolefins, and reactive processing. In this article free‐radical initiator decomposition pathways are reviewed. Initiator reactivity is related to chemical structure and to first‐order decomposition parameters such as temperature, frequency factor, and activation energy. Reactivity of derived free radicals is also related to structure and to the occurrence of secondary reactions such as β‐scission and induced decomposition. The energy and the chemical properties of the free radicals determine commercial utility; thus the interrelation of initiators, their kinetics, and the radicals produced provide guidelines for initiator selection.
A Data-driven Prognostic Architecture for Online Monitoring of Hard Disks Using Deep LSTM Networks. (2018)

With the advent of pervasive cloud computing technologies, service reliability and availability are becoming major concerns,especially as we start to integrate cyber-physical systems with the cloud networks. A number of smart and connected community systems such as emergency response systems utilize cloud networks to analyze real-time data streams and provide context-sensitive decision support.Improving overall system reliability requires us to study all the aspects of the end-to-end of this distributed system,including the backend data servers. In this paper, we describe a bi-layered prognostic architecture for predicting the Remaining Useful Life (RUL) of components of backend servers,especially those that are subjected to degradation. We show that our architecture is especially good at predicting the remaining useful life of hard disks. A Deep LSTM Network is used as the backbone of this fast, data-driven decision framework and dynamically captures the pattern of the incoming data. In the article, we discuss the architecture of the neural network and describe the mechanisms to choose the various hyper-parameters. We describe the challenges faced in extracting effective training sets from highly unorganized and class-imbalanced big data and establish methods for online predictions with extensive data pre-processing, feature extraction and validation through test sets with unknown remaining useful lives of the hard disks. Our algorithm performs especially well in predicting RUL near the critical zone of a device approaching failure.The proposed architecture is able to predict whether a disk is going to fail in next ten days with an average precision of 0.8435.In future, we will extend this architecture to learn and predict the RUL of the edge devices in the end-to-end distributed systems of smart communities, taking into consideration context-sensitive external features such as weather.
Application of multi‐wavelet seismic trace decomposition and reconstruction to seismic data interpretation and reservoir characterization (2006)

A seismic trace is decomposed into a set of Ricker wavelets of different dominant frequencies and amplitudes. The seismic trace can then be accurately reconstructed with all the wavelets in the set of wavelets. With certain targeted objective in mind, a new seismic trace can be reconstructed with a selected subset of the wavelets, which is found very helpful in seismic data interpretation and reservoir characterization.
Selective detection and transport of fully matched DNA by DNA‐loaded microtubule and kinesin motor protein (2006)

DNA-loaded microtubules (MTs) moving on a kinesin motor protein-coated substrate can selectively hybridize with a target fully matched DNA over single-base mismatched DNA and transport it. This technique is capable of collecting target biomolecules toward one point site to design new methodology of DNA analysis.
High-efficiency, high-dispersion diffraction gratings based on total internal reflection (2004)

We report a new class of high-dispersion immersed diffraction gratings for which the reflective nature of the diffraction is provided by the phenomenon of total internal reflection (TIR) regardless of grating tooth shape. Thus, the component can be fabricated from a single dielectric material and requires no metallic or dielectric film layers for high reflection diffraction efficiency. With the absence of metallic absorption, diffraction efficiencies of these TIR gratings can reach more than 99% for 15-20-nm spectral bandwidths, making them suitable for many laser-based technologies.
Ultrashallow secondary ion mass spectroscopy depth profiling of doping spikes and Si/SiGe/Si heterostructures using different primary species (1998)

We present high resolution secondary ion mass spectroscopy (SIMS) depth profiles for characterization of Si/SiGe/Si heterojunction bipolar transistors (HBT). We show by device simulation that to achieve transit frequencies of more than 90 GHz for a given HBT, it is necessary to keep the decay length of the B profile in the SiGe base layer smaller than 2.5 nm. This formulates stringent requirements for the processing technology and for profile characterization techniques. In time-of-flight secondary ion mass spectroscopy (TOF-SIMS) depth profiling (dual-beam mode), we used a low energy (0.5–3 keV) sputter gun operating with different sputter gases (Ar, O2, SF6) to achieve a profile decay length below 2.5 nm. The full width at half-maximum (FWHM) of 3 nm B doping spikes in HBT structures is well-characterized using an Ar+ ion beam of 1 keV. To measure B base doping with a decay length of about 1 nm it is necessary to lower the energy of the sputtering ion beam to less than 2 keV for SF6 and to 0.6 keV for Ar sputtering. The decay length depends linearly on the sputtering ion beam energy in the low energy range. The slope of this dependence is smaller for SF6 sputtering than for Ar sputtering.
Functional regulatory T cells and allergen immunotherapy (2010)

These findings support a mechanistic role for Treg early in allergen immunotherapy. Research is required to clarify the precise Treg subsets involved, their specificity and how their activity can be enhanced during immunotherapy by appropriate allergen form, optimal site of administration and use of adjuvants and adjunct therapies.
Integrity of Proteins in Human Saliva after Sterilization by Gamma Irradiation (2010)

Microbial contamination of whole human saliva is unwanted for certain in vitro applications, e.g., when utilizing it as a growth substratum for biofilm experiments. The aim of this investigation was to test gamma irradiation for its suitability to sterilize saliva and to investigate the treatment's influence on the composition and integrity of salivary proteins in comparison to filter sterilization. For inhibition of bacterial growth by gamma irradiation, a sterility assurance level of 10(-6) was determined to be reached at a dose of 3.5 kGy. At this dose, the integrity of proteins, as measured by fluorescence, circular dichroism, and gel electrophoretic banding pattern, and the enzymatic activities of salivary amylase and lysozyme were virtually unchanged. Filtration reduced the total protein concentration to about half of its original value and decreased lysozyme activity to about 10%. It can be concluded that irradiation is suitable for sterilizing whole saliva in its native form.