gebhart/patrepeval huggingface dataset:
Nutritional Enhancement of n‐3 and n‐6 Fatty Acids in Rotifers and <i>Artemia</i> Nauplii by Feeding Spray‐dried <i>Schizochytrium</i> sp. (1996)

Abstract A docosahexaenoic acid (DHA), 22:6(n‐3), rich strain of Schizochytrium sp. was used in a spray‐dried form to evaluate the enhancement of highly unsaturated fatty acids (HUFAs) in Artemia franciscana nauplii (Utah biotype) and the rotifer Brachionus plicatilis . This heterotrophic microalga was selected because of its high concentration of the longest chain HUFAs in the n‐3 and n‐6 series, DHA and docosapentaenoic acid (DPA), 22:5(n‐6), respectively. When 24‐h‐old Artemia nauplii were fed 400 mg/L of the algae for 24 h, the DHA content of the nauplii went from undetectable levels to 0.8% of dry weight and the omega‐3 HUFA eicosapentaenoic acid (EPA), 20:5n‐3, content went from 0.1% to 0.5% of dry weight in the nauplii. Similarly, 22:5(n‐6) increased in the nauplii from undetectable levels to 0.4% of dry weight, with a concomitant increase in arachidonic acid, (20:4n‐6), from trace to 0.3% of dry weight even though there was no arachidonic acid in the algal biomass. Similar enrichment patterns were observed in rotifers. The results suggest that spray‐dried cells of Schizochytrium sp. are effective in enriching Artemia naupli and rotifers in both n‐3 and n‐6 HUFAs. The results also suggest that Artemia nauplii and rotifers are capable of readily retroconverting 22:6(n‐3) to 20:5(n‐3) and 22:5(n‐6) to 20:4(n‐6) through the process of β‐oxidation, a well‐known process in mammals.
Interactions of <i>Escherichia coli</i> σ <sup>70</sup> within the transcription elongation complex (1999)

A functional transcription elongation complex can be formed without passing through a promoter by adding a complementary RNA primer and core Escherichia coli RNA polymerase in trans to an RNA-primed synthetic bubble-duplex DNA framework. This framework consists of a double-stranded DNA sequence with an internal noncomplementary DNA "bubble" containing a hybridized RNA primer. On addition of core polymerase and the requisite NTPs, the RNA primer is extended in a process that manifests most of the properties of in vitro transcription elongation. This synthetic elongation complex can also be assembled by using holo rather than core RNA polymerase, and in this study we examine the interactions and fate of the sigma(70) specificity subunit of the holopolymerase in the assembly process. We show that the addition of holopolymerase to the bubble-duplex construct triggers the dissociation of the sigma factor from some complexes, whereas in others the RNA oligomer is released into solution instead. These results are consistent with an allosteric competition between sigma(70) and the nascent RNA strand within the elongation complex and suggest that both cannot be bound to the core polymerase simultaneously. However, the dissociation of sigma(70) from the complex can also be stimulated by binding of the holopolymerase to the DNA bubble duplex in the absence of a hybridized RNA primer, suggesting that the binding of the core polymerase to the bubble-duplex construct also triggers a conformational change that additionally weakens the sigma-core interaction.
Cutting Edge: Conventional CD8α+ Dendritic Cells Are Preferentially Involved in CTL Priming After Footpad Infection with Herpes Simplex Virus-1 (2003)

CTL play a major role in immunity to HSV type 1, but little is known about the priming process. In this study, we have examined the class I-restricted presentation of an immunodominant determinant from HSV-1 glycoprotein B after footpad infection. We have found that the only cell types capable of presenting this determinant in draining popliteal lymph nodes within the first 3 days after infection are the CD11c(+)CD8alpha(+)CD45RA(-) dendritic cells. Given that such class I-restricted presentation is essential for CTL priming, this implies that these conventional CD8alpha(+) dendritic cells are the key subset involved in CTL immunity to this virus.
General, Efficient Route to Thiophene-1-Oxides and Well-Defined, Mixed Thiophene-Thiophene-1-Oxide Oligomers (1999)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTGeneral, Efficient Route to Thiophene-1-Oxides and Well-Defined, Mixed Thiophene-Thiophene-1-Oxide OligomersBiwang Jiang and T. Don TilleyView Author Information Department of Chemistry, University of California at Berkeley, Berkeley, California 94720-1460 Cite this: J. Am. Chem. Soc. 1999, 121, 41, 9744–9745Publication Date (Web):September 30, 1999Publication History Received8 July 1999Published online30 September 1999Published inissue 1 October 1999https://pubs.acs.org/doi/10.1021/ja992365thttps://doi.org/10.1021/ja992365trapid-communicationACS PublicationsCopyright © 1999 American Chemical SocietyRequest reuse permissionsArticle Views1671Altmetric-Citations72LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Anions,Oligomers,Oxidation,Sandwich compounds,Thiophenes Get e-Alerts
A Tensor-Based Multiattributes Visual Feature Recognition Method for Industrial Intelligence (2020)

Industrial Internet-of-Things (IIoT) has revolutionized almost every aspect of industrial manufacturing through industrial intelligence by incorporating production equipment, mobile terminals, and smart devices with wireless or wired networks. However, industrial visual information, such as images, videos, graphs, and texts, generated and collected from the industrial processes, contains various kinds of hidden value for industrial intelligence. Therefore, for the trend of providing ubiquitous industrial intelligence, new paradigms of perception and processing technologies of visual information such as recognition methods are required. However, industrial visual information is heterogeneous and complex with multiattributes, which presents significant challenges on visual information perception and processing technologies such as multiattributes recognition method. In this article, to provide industrial intelligence, a tensor-based visual feature recognition method is used to recognize the object from the perspective of multiattributes with the combination of attributes. To demonstrate its practical implementation, a case study about the industrial intelligence on the faulty location and diameter of bearings in the IIoT is described. Also, experiments on object recognition are carried out on the public image set COIL-100 to demonstrate the performance of the proposed method.
An Effective Method of Probe Calibration in Phase-Resolved Near-Field Scanning for EMI Application (2012)

Near-field scanning can be used to determine the far-field emissions of electronic devices. In general, this requires phase-resolved electric and magnetic near-field data. To capture a broad frequency range relatively quickly, a multichannel oscilloscope can be used for data capture. The phase relationship of the fields between different space points and between the electric and the magnetic field needs to be known. Consequently, it is required to determine the complex-valued probe factor (PF) of the probe, cable, and amplifier chain. This paper presents a fast and efficient calibration method which uses the same setup and instruments during calibration and measurement, and it allows for easy and economical integration of the calibration hardware and software into the scanning system. Known fields are created by a microstrip trace driven with a comb generator. By referencing measured data to this known field, the PF is obtained over a broad frequency range by capturing one time-domain waveform.
Acute decompensated heart failure (2007)

[The authors respond:] In our review, in particular in the section on loop diuretics, we attempted to outline many of the controversies associated with the treatment of volume overload in acute decompensated heart failure.[1][1] We provided 3 references to support the statement that use of loop
Magnetic properties of α‐Fe <sub>2</sub> O <sub>3</sub> nanopallets (2017)

Abstract It is the result of a systemic study about uniform hematite nanopallets with length of about 100 nm, width of about 30 nm, and thickness of less than 10 nm. The sample has superparamagnetic (SPM) properties above the blocking temperature of ~16 K. The temperature dependence of magnetization was well fitted by Bloch T 3/2 law considering the dipolar interaction of the particles. The field dependence of magnetization was fitted with revised Langevin equation. The magnetization of the weak ferromagnetic (WF) canted spins contributes to the linear portion in the high field region; the surface uncompensated spins and the parasitic ferromagnetic moments due to the canted spins both contribute to the particle moments and the superparamagnetic behavior.
Synthesis of Polyethylene Magnetic Nanoparticles (2002)

ABSTRACT Very low molecular weight polyethylene (average MW 700 g/mole) magnetic nanocomposite particles were synthesized by nonsolvent and temperature induced crystallization along with ultrasonication. The particles are further coated with poly dl-lactic acid to functionalize the polyethylene particles for biomedical applications. A solvent-nonsolvent emulsion was made with polyethylene and surface modified iron oxide and was raised to very high temperature followed by rapid cooling. Decalin and octamethylcyclotetrasiloxane (OMCTS) were used as solvent and tetraglyme as nonsolvent. The synthesized particles were found to have two different types of morphology. Particles sizes can be varied depending on the choice of solvent, polymer concentration and amplitude of ultrasonication. The composite particles were characterized by scanning transmission electron microscopy. Magnetic properties of the composite particles were also studied.
Tibiofemoral movement 3: full flexion in the living knee studied by MRI (2000)

We studied active flexion from 90 degrees to 133 degrees and passive flexion to 162 degrees using MRI in 20 unloaded knees in Japanese subjects. Flexion over this arc is accompanied by backward movement of the medial femoral condyle of 4.0 mm and by backward movement laterally of 15 mm, i.e., by internal rotation of the tibia. At 162 degrees the lateral femoral condyle lies posterior to the tibia.
Analysis and Performance Investigation of a Cascaded Multilevel STATCOM for Power System Voltage Regulation (2007)

This paper presents an analysis of a cascaded multilevel STATCOM based on space vector theory. Simple relationships between reactive current, capacitor current and delayed angle are derived from the steady state analysis. The switching pattern design and the optimization technique to achieve the output voltage waveform which conforms to the IEC standard for harmonics are described and the design results are verified by the harmonics analysis. A typical 230 kV power system with a 100 MVA cascaded 5-link, 11-level STATCOM is simulated on PSCAD/EMTDC digital simulator. Due to unequal duty cycles, the voltage drops across DC capacitors of the converters are unequal and a simple voltage equalization technique without additional control loop is proposed. The dynamic performances of the casc aded multilevel STATCOM, which was subjected to disturbances and change of commands, are illustrated. Simulation results indicate that the proposed system can provide fast reactive current response and fast equalization the DC capacitor voltages. The harmonics content of the output voltage waveform can be controlled within an acceptable level even it is only a 5-link, 11-level cascaded STATCOM.
Natural and synthetic coumarins as potential anticancer agents (2015)

Coumarins, natural or synthetic, due to their wide range of biological activities, have become an interesting subject of investigation for many researchers. Coumarin scaffold has proven to have an important role in anticancer drug development due to a fact that many of its derivatives have shown an anticancer activity on various cell lines. Action of coumarins on tumour cells is carried out via different mechanisms and some of them show very good selectivity toward the cancer cells. In this work a brief literature review (2010-2015) on coumarins as potential anticancer drugs is given, which can serve as an excellent tool for future investigations on design and synthesis of such derivatives.
Wnt4 Participates in the Formation of Vertebrate Neuromuscular Junction (2012)

Neuromuscular junction (NMJ) formation requires the highly coordinated communication of several reciprocal signaling processes between motoneurons and their muscle targets. Identification of the early, spatially restricted cues in target recognition at the NMJ is still poorly documented, especially in mammals. Wnt signaling is one of the key pathways regulating synaptic connectivity. Here, we report that Wnt4 contributes to the formation of vertebrate NMJ in vivo. Results from a microarray screen and quantitative RT-PCR demonstrate that Wnt4 expression is regulated during muscle cell differentiation in vitro and muscle development in vivo, being highly expressed when the first synaptic contacts are formed and subsequently downregulated. Analysis of the mouse Wnt4⁻/⁻ NMJ phenotype reveals profound innervation defects including motor axons overgrowing and bypassing AChR aggregates with 30% of AChR clusters being unapposed by nerve terminals. In addition, loss of Wnt4 function results in a 35% decrease of the number of prepatterned AChR clusters while Wnt4 overexpression in cultured myotubes increases the number of AChR clusters demonstrating that Wnt4 directly affects postsynaptic differentiation. In contrast, muscle structure and the localization of several synaptic proteins including acetylcholinesterase, MuSK and rapsyn are not perturbed in the Wnt4 mutant. Finally, we identify MuSK as a Wnt4 receptor. Wnt4 not only interacts with MuSK ectodomain but also mediates MuSK activation. Taken together our data reveal a new role for Wnt4 in mammalian NMJ formation that could be mediated by MuSK, a key receptor in synaptogenesis.
Finally! A human pancreatic β cell line (2011)

For decades, investigators have made numerous attempts to generate human pancreatic β cell lines that could be used to advance β cell biology, facilitate drug discovery, and provide a pathway to β cell replacement therapy for the treatment of diabetes. In this issue of the JCI, Ravassard and colleagues report that this has finally been achieved successfully with a multistep process that led to the generation of cells, which they termed EndoC-βH1 cells, that secreted insulin in response to glucose challenge.
Cultura virtual e subjetividade na idade mídia: contemplações críticas com Joana Peixoto (2019)

A temática da cultura virtual e midiática presente nas discussões instauradas na academia traz pontos e contrapontos que oportunizam críticas e debates. Por um lado, desafiam consensos capazes de cristalizar e engessar ideias e ações, por outro, distorcem imagens tão bem desenhadas na história das telecomunicações. Nessa direção, o propósito dessa entrevista é trazer à tona algumas contemplações sobre as controvertidas relações entre educação e tecnologias na sociedade neoliberal e seus efeitos na produção de subjetividades. Para tanto, debruçamo-nos sobre esse campo de conhecimento, por meio de uma entrevista realizada com a pesquisadora brasileira, Joana Peixoto (J.P.), que se destaca no cenário nacional pelos legados e inúmeras contribuições registradas na área em que atua. Considerando a larga experiência como pesquisadora e docente na área da educação, apresentamos, de modo breve, um panorama da formação da entrevistada, bem como os interesses que possui. Joana Peixoto possui produção arbitrada e divulgada em periódicos qualificados com trabalhos científicos. Por essa razão pensamos ser muito relevantes as experiências constituídas pela Professora no terreno da formação de professores, assim como as relações com as mídias eletrônicas e tecnologias digitais.
Near-Real-Time Cloud Auditing for Rapid Response (2012)

Due to the rapid emergence of Information Technology, cloud computing provides assorted advantages to service providers, developers, organizations, and customers with respect to scalability, flexibility, cost-effectiveness, and availability. However, it also introduces new challenges and concerns, especially in terms of security and privacy. One of the major security obstacles to widespread adoption of cloud computing is the lack of near-real-time audit ability. In particular, near-real-time cloud auditing, which provides timely evaluation results and rapid response, is the key to assuring the cloud. In this paper, we discuss security and privacy concerns in cloud computing and the current status of cloud auditing efforts. Next, we address the strategies for reliable cloud auditing and analyze the deficiencies of current approaches. We then discuss the summary of our case study with Amazon Cloud Watch, which is one of the most developed cloud-monitoring APIs.
People Detection in Fish-eye Top-views (2017)

Is the detection of people in top views any easier than from the much researched canonical fronto-parallel views (e.g. Caltech and INRIA pedestrian datasets)? We show that in both cases people appearance variability and false positives in the background limit performance. Additionally, we demonstrate that the use of fish-eye lenses further complicates the top-view people detection, since the person viewpoint ranges from nearly-frontal, at the periphery of the image, to perfect top-views, in the image center, where only the head and shoulder top profiles are visible. We contribute a new top-view fish-eye benchmark, we experiment with a state-of-the-art person detector (ACF) and evaluate approaches which balance less variability of appearance (grid of classifiers) with the available amount of data for training. Our results indicate the importance of data abundance over the model complexity and additionally stress the importance of an exact geometric understanding of the problem, which we also contribute here.
EGF-receptor-mediated mammary epithelial cell migration is driven by sustained ERK signaling from autocrine stimulation (2007)

EGF family ligands are synthesized as membrane-anchored precursors whose proteolytic release yields mature diffusible factors that can activate cell surface receptors in autocrine or paracrine mode. Expression of these ligands is altered in pathological states and in physiological processes, such as development and tissue regeneration. Despite the widely documented biological importance of autocrine EGF signaling, quantitative relationships between protease-mediated ligand release and consequent cell behavior have not been rigorously investigated. We thus explored the relationship between autocrine EGF release rates and cell behavioral responses along with activation of ERK, a key downstream signal, by expressing chimeric ligand precursors and modulating their proteolytic shedding using a metalloprotease inhibitor in human mammary epithelial cells. We found that ERK activation increased monotonically with increasing ligand release rate despite concomitant downregulation of EGF receptor levels. Cell migration speed was directly related to ligand release rate and proportional to steady-state phospho-ERK levels. Moreover, migration speed was significantly greater for autocrine stimulation compared with exogenous stimulation, even at comparable phospho-ERK levels. By contrast, cell proliferation rates were approximately equivalent at all ligand release rates and were similar regardless of whether the ligand was presented endogenously or exogenously. Thus, in our mammary epithelial cell system, migration and proliferation are differentially sensitive to the mode of EGF ligand presentation.
Interferometric scanning optical microscope for surface characterization (1992)

A phase-sensitive scanning optical microscope is described that can measure surface height changes down to 0.1 nm. This is achieved by using two heterodyne Michelson interferometers in parallel. One interferometer probes the sample with a tightly focused beam, and the second has a collimated beam that illuminates a large area of the surface, providing a large area on sample reference. This is facilitated by using a specially constructed objective lens that permits the relative areas illuminated by the two probe beams to be varied both arbitrarily and independently, thus ensuring an accurate absolute phase measurement. We subtracted the phase outputs from each interferometer to provide the sample phase information, canceling the phase noise resulting from microphonics in the process. Results from a prototype version of the microscope are presented that demonstrate the advantages of the system over existing techniques.
MagicEyes: A Large Scale Eye Gaze Estimation Dataset for Mixed Reality (2020)

With the emergence of Virtual and Mixed Reality (XR) devices, eye tracking has received significant attention in the computer vision community. Eye gaze estimation is a crucial component in XR -- enabling energy efficient rendering, multi-focal displays, and effective interaction with content. In head-mounted XR devices, the eyes are imaged off-axis to avoid blocking the field of view. This leads to increased challenges in inferring eye related quantities and simultaneously provides an opportunity to develop accurate and robust learning based approaches. To this end, we present MagicEyes, the first large scale eye dataset collected using real MR devices with comprehensive ground truth labeling. MagicEyes includes $587$ subjects with $80,000$ images of human-labeled ground truth and over $800,000$ images with gaze target labels. We evaluate several state-of-the-art methods on MagicEyes and also propose a new multi-task EyeNet model designed for detecting the cornea, glints and pupil along with eye segmentation in a single forward pass.
Simple Reduction of Heteroaromatic Esters to Alcohols Using a Sodium Borohydride–Methanol System (2005)

Núbia Boechata, Jorge Carlos Santos da Costaa, Jorge de Souza Mendonçaa, Karla Ceodaro Paesa, Elisa Lopes Fernandesa, Pedro Santos Mello de Oliveiraa, Thatyana Rocha Alves Vasconcelosa & Marcus Vinícius Nora de Souzaa* a FioCruz-Fundação Oswaldo Cruz , Instituto de Tecnologia em Fármacos‐Far Manguinhos , Manguinhos , Rio de Janeiro , Brazil
Thermal imaging research needs for first responders : (2005)

Certain commercial entities, equipment, or materials may be identified in this document in order to describe an experimental procedure or concept adequately. Such identification is not intended to imply