gebhart/patrepeval huggingface dataset:
Authentication and authorization orchestrator for microservice-based software architectures (2018)

Nowadays the demand for cloud and IT services is gaining more and more popularity, therefore, the various IT solutions which implement them need to face some challenges. More and more intensive user activities require the use of well-scalable and distributed solutions which (from software technology point of view) disassembles classical monolithic architectures into microarchitectures. Consequently, instead of one or a few well-determined application-level points of access, the system must provide many points of access for the users and the other parts of the application involving many authentication and authorization processes. Moreover, the number and the location of these points of access are constantly changing during the running time implying new challenges in the security and the management field. One of the solutions is to give an encrypted token (typically implemented by a JSON Web Token) to the users after their logins which will be attached to each query. In this paper we develop an authentication and authorization orchestrator for the microservices which can manage the tokens (create and delete) needed to the authentication and authorization of the users. The orchestrator service contains a client API to provide the necessary information for the microservice in Java environment without the modification of the original application.
A Simple and Parameter Method for Computing Flood Hydrographs (1995)

A simple 3-parameter method, possessing the simplicity of the unit hydrograph method but having the positive features of the kinematic wave method, has been introduced. The simplicity arises from the use of the unit hydrograph method of synthesising a hydrograph by computing, first, for separate hydrographs associated with different rainfall intensities, before combining them to get the final hydrograph. The positive features of the kinematic wave method comes from a set of dimensionless equations, derived from kinematic wave theory, used to synthesise the separate hydrographs. Two of the parameters, watershed-averaged slope S and length L, are defined from the physical characteristics of a watershed. Systematic sensitivity analyses were carried out to investigate how the remaining parameter, a watershed-averaged roughness N, varies with a watershed's plane and channel roughnesses, Np and Nc, respectively. A multiple linear regression equation for N, in terms of Np and Nc, was derived. It was tested and found to be adequate for computing N for an actual watershed.
Dynamic recognition in the omni-writer frame: Application to hand-printed text recognition (2002)

We present in this contribution a new system dedicated to the analysis of hand-printed dynamic text. It appears as an alternative to merchandized personal digital assistants (PDAs) which are very user restricting and automatic cursive word recognizers that have been developed in laboratories and have still not reached a marketable target in spite of their accuracy. The whole treatment process, from the acquisition to the efficient reading, is integrated in a user-friendly interface. The results on an omni-writer text database are very encouraging. They should be improved by using a new lexicon driven expert that adapts the recognition to the writer.
Prediction of Radio Channels for OFDM by Autoregressive Modeling (2006)

This paper presents a prediction algorithm for OFDM radio channels in either time or frequency direction that explores the over sampling of the channel transfer function compared to the maximum Doppler shift and the maximum excess delay. The algorithm derives an autoregressive model utilized for prediction. Pre-filtering of channel estimates are concerned and the prediction approach is appraised as a tool for adaptive symbol mapping.
Intra-Nets: open messaging technology and opportunities for user driven information spaces (2002)

The growth of privately held networks (dedicated to specific business and organizational goals) and the migration of Internet style technologies to these networks has been substantial in recent years. This situation has created unique opportunities and challenges to professionals working in this "intra-net" environment. This paper describes some of the technical foundations, unique characteristics and some early results of deploying systems in that environment. It provides an overview for some of the unique characteristics of hypermedia based client server applications on these networks, as well as an introduction to the issues and opportunities within the intra-net environment. Topics addressed include; message based services, "out of band" mail handling, security issues, collaborative opportunities and developing custom information.
Advancing Commercialization of Algal Biofuel through Increased Biomass Productivity and Technical Integration (2016)

The proposed project built on the foundation of over several years years of intensive and ground-breaking R&D work at Cellana's Kona Demonstration Facility (KDF). Phycological and engineering solutions were provided to tackle key cultivation issues and technical barriers limiting algal biomass productivity identified through work conducted outdoors at industrial (1 acre) scale. The objectives of this project were to significantly improve algal biomass productivity and reduce operational cost in a seawater-based system, using results obtained from two top-performing algal strains as the baseline while technically advancing and more importantly, integrating the various unit operations involved in algal biomass production, processing, and refining.
Using IDDs for Packet Filtering (2002)

Firewalls are one of the key technologies used to control the traffic going in and out of a network. A central feature of the firewall is the <em>packet filter</em>. In this paper, we propose a complete framework for packet classification. Through two applications we demonstrate that both performance and security can be improved.<br /> <br />We show that a traditional ordered rule set can always be expressed as a first-order logic formula on integer variables. Moreover, we emphasize that, with such specification, the packet filtering problem is known to be constant time. We propose to represent the first-order logic formula as <em> Interval Decision Diagrams</em>. This structure has several advantages. First, the algorithm for removing redundancy and unnecessary tests is very simple. Secondly, it allows us to handle integer variables which makes it efficient on a generic CPUs. And, finally, we introduce an extension of IDDs called <em>Multi-Terminal Interval Decision Diagrams</em> in order to deal with any number of policies.<br /> <br />In matter of efficiency, we evaluate the performance our framework through a prototype toolkit composed by a <em> compiler</em> and a <em>packet filter</em>. The results of the experiments shows that this method is efficient in terms of CPU usage and has a low storage requirements.<br /> <br />Finally, we outline a tool, called <em>Network Access Verifier</em>. This tool demonstrates how the IDD representation can be used for verifying access properties of a network. In total, potentially improving the security of a network.
Irreversible Electrowetting on Thin Fluoropolymer Films (2007)

A study was conducted to investigate electrowetting reversibility associated with repeated voltage actuations for an aqueous droplet situated on a silicon dioxide insulator coated with an amorphous fluoropolymer film ranging in thickness from 20 to 80 nm. The experimental results indicate that irreversible trapped charge may occur at the aqueous-solid interface, giving rise to contact angle relaxation. The accumulation of trapped charge was found to be related to the applied electric field intensity and the breakdown strength of the fluoropolymer. On the basis of the data, an empirical model was developed to estimate the amount of trapped charge in the fluoropolymer as well as the voltage threshold for the onset of irreversible electrowetting.
Context-aware physiological data acquisition and processing with wireless sensor networks (2010)

Wearable devices are a novel method for sensing physiological parameters of subjects. Even though some of them are equipped with multiple sensors, usually each parameter is analyzed separately. It often leads to false alarm generation and thus limited acceptability of these systems. We propose not only to combine multi-sensor data available on the wearable device, but also to interface the wearable nodes with a mesh network of sensing devices deployed in the environment. Such solution enables context-sensitive analysis of the physiological data leading to correct situation assessment and reliable alarm generation. The wireless sensor network provides reliable and low power communication medium for the wearable devices. We base our system on ECG and acceleration data acquired by the wearable nodes along with descriptive localization and environmental data from the wireless sensor network. We present the architecture of the proposed system and an example implementation both indoors and outdoors. The proposed system is easy to implement, flexible and scalable which makes it suitable for large area deployments.
Photo-Voltaic System Using Micro-Optics (2012)

A photo-voltaic system is under development that uses large arrays of plastic micro-lenses, each illuminating a tiny PV cell stack. This 100-sun system has ±2.5° field of view. Cell efficiency target is >50% with 40% overall system efficiency.
[Application of mesenchymal stem cell in immunotherapy--review]. (2005)

There has been an increasing interest in recent years on mesenchymal stem cell (MSC). It is well known that MSCs are capable of self-renewal and differentiating into many cell lineages. MSC can be expended to a large quantity that is required for clinical transplantation. Recent studies show that MSC have potential application in immune diseases due to their unique immunologic characteristics, such as low immunogenicity and immunoregulatory function. But their immunoregulatory mechanism is not yet clear. This review discusses the advances in researches on the mechanism of MSCs' immunoregulatory function and potential clinical application in immune disease and organ transplantation.
Mechanisms of bacterial persistence during stress and antibiotic exposure (2016)

Bacterial persister cells avoid antibiotic-induced death by entering a physiologically dormant state and are considered a major cause of antibiotic treatment failure and relapsing infections. Such dormant cells form stochastically, but also in response to environmental cues, by various pathways that are usually controlled by the second messenger (p)ppGpp. For example, toxin-antitoxin modules have been shown to play a major role in persister formation in many model systems. More generally, the diversity of molecular mechanisms driving persister formation is increasingly recognized as the cause of physiological heterogeneity that underlies collective multistress and multidrug tolerance of persister subpopulations. In this Review, we summarize the current state of the field and highlight recent findings, with a focus on the molecular basis of persister formation and heterogeneity.
Automated peritoneal dialysis with 'on-line'-prepared bicarbonate-buffered dialysate: technique and first clinical experiences (1998)

On-line preparation of PD fluid with the AK 100 Ultra is easy and safe to handle. APD with dialysate containing 37 mmol/l bicarbonate provides improved acid base balance and possibly improved biocompatibility, and may lead to a significant cost reduction. Further development in order to provide smaller machines and more precise ways of achieving a desired dialysate glucose concentration is necessary.
The Clinical Study on the Constitutional symptomatic pattern of Soyangin and Taeumin inpatients in stroke (2000)

Objective ; The purpose of this study is to find out the constitutional symptomatic pattern of Soyangin and Taeumin through investigation of difference between two groups in stroke. Method ; 70 inpatients(Soyangin 31, Taeumin 39) in stroke, admitted into Kyung-Hee Oriental Hospital from 1. July. 1999 to 20. Sept. 1999, were investigated through questionnare which consists of 16 parts 155 questions, and the problems which have significant difference between Soyangin and Taeumin group were analyzed statistically. Result 1. The analysis of general characteristic difference between Soyangin and Taeumin group (1) The number of Soyangin patients is 31, Taeumin 39 and the number of Male patients 43, Female 27. (2) The mean weight of Taeumin group is heavier than that of Soyangin group and the degree of obesity of Taeumin group higher. (3) The number of patients who have smoking history is more at Soyangin group. (4) In neurological problem, dizziness is more complained of in Soyangin group. 2. The analysis about the result of Questionnare (1) In problems related with 'Sleeping', the time of going to bed and getting up and the duration of sleeping are more irregular in Taeumin group. (2) In problems related with 'Defecation', the shape of stool is more variable in Taeumin group. (3) In problems related with 'Urination', Soyangin group have more complaint. (4) In problems related with 'The condition of digestion', Taeumin group have a good appetite and more compalint in lower abdominal region, but on the contrary Soyangin group lose appetite and have more complaint in upper abdominal region. (5) In problems related with 'Head and Face', Soyangin group have more complaint. (6) In problems related with 'Eye, Ear and Nose', Soyangin group have more complaint at eye and ear. (7) In promlems related with 'Chest region', Soyangin group easily feel choked up and Taeumin group heart throbs. (8) In problems related with 'Skin', Taeumin group easily feel change of color tone at skin and Soyangin group dry.
Clinical Perspectives on Hereditary Hemochromatosis (2008)

Hereditary hemochromatosis (HH) comprises a group of inherited disorders of iron metabolism that can result in progressive iron overload, morbidity, and mortality, generally in adulthood. HFE-related HH is the most common type of HH and will form the core of this discussion. The discovery of new proteins and gene mutations has defined other types of HH, termed non-HFE HH. The regulatory protein hepcidin has a central role in iron homeostasis in these disorders. While the liver is the predominant organ of iron deposition and iron-overload-related disease in HFE-related HH, involvement of extrahepatic tissue can also result in morbidity and mortality if the disorder is not diagnosed before organ damage develops. This review traverses the road from HFE genotype to phenotype with a focus on clinical penetrance, modifier factors for disease expression, and current thoughts and controversies on HH diagnosis and screening.
Type II adenylylcyclase integrates coincident signals from Gs, Gi, and Gq (1993)

Agonists for Gi-coupled receptors augment Gs-stimulated cAMP synthesis in human embryonic kidney (HEK) 293 cells transiently expressing the type II isozyme of adenylylcyclase (AC-II). This augmentation, mediated by beta gamma subunits released from activated Gi, can be blocked by expression of the alpha subunit (alpha t) of retinal transducin (Gt), which presumably sequesters free beta gamma (Federman, A. D., Conklin, B. R., Schrader, K. A., Reed, R. R., and Bourne, H. R. (1992) Nature 356, 159-161). The alpha subunit of Gq, representing a G protein family distinct from both Gs and Gi, mimicked the inhibitory effect of alpha t, suggesting that hormonal stimulation of endogenous Gq might also release beta gamma subunits and thereby augment AC-II activity. Agonists for either of two Gq-coupled receptors did augment Gs-stimulated cAMP synthesis in HEK-293 cells expressing AC-II, but this effect was not blocked by expression of alpha t. The increased stimulation of AC-II was probably not mediated by the release of beta gamma subunits from Gq but rather by activation of protein kinase C (PKC) because of the following. (a) Phorbol esters, which activate PKC directly, elevated cAMP 2-fold in HEK-293 cells transfected with AC-II; this increase was synergistic with Gs-mediated activation of AC-II. (b) Treatments that partially inhibit or down-regulate PKC also partially prevented stimulation of AC-II by phorbol esters or by agonists for Gq-coupled receptors. Taken together, these results indicate that AC-II can integrate regulatory signals transmitted by at least three classes of G proteins; extracellular signals acting through Gs are enhanced synergistically by simultaneous signals transduced by Gi or Gq and mediated via beta gamma or PKC, respectively.
Structure-activity studies of human sterol carrier protein 2. (1994)

Recombinant human sterol carrier protein 2 (SCP2) variants were generated by site-directed mutagenesis and expression in Escherichia coli. The ability of the variants to stimulate microsomal conversion of 7-dehydrocholesterol to cholesterol (sterol carrier activity) and to transfer cholesterol and phosphatidylcholine from donor small unilamellar vesicles to acceptor membranes (cholesterol and phosphatidylcholine transfer activities) was compared with wild-type recombinant SCP2. Our results indicate that all measured activities of recombinant human pre-SCP2 (including the 20-amino acid leader sequence) and mature SCP2 were similar. Expressed glutathione S-transferase fusion proteins (GST-SCP2 and GST-pre-SCP2) possessed considerable activity, suggesting that steric obstruction at the amino terminus causes only minor inactivation. The effect of progressive removal of peptides from the carboxyl terminus showed that amino acids between Lys100 and Asn104 are essential for SCP2 activity. This conclusion was substantiated by the observation that replacing Asn104 with Asp or Ile caused considerable inactivation, whereas replacing Met105 with Leu had almost no effect. Since N-ethylmaleimide is known to inhibit SCP2 activity, substitutions were also introduced in the vicinity of Cys71. Whereas Val71 and Ser71 variants possessed wild-type activity, replacing Asp70 with Asn almost completely abolished SCP2 activity. Further, the importance of residues located close to the amino terminus was indicated by complete inactivation of a 10-amino-terminal amino acid deletion mutant and by replacing Leu20 with Glu. Circular dichroism results showed that Leu20 and Asp70 may serve to stabilize the overall fold, whereas residue 104 appears to play a role in the specific lipid binding and/or transfer activity of SCP2.
Mechanotherapy: how physical therapists’ prescription of exercise promotes tissue repair (2009)

Mechanotransduction is the physiological process where cells sense and respond to mechanical loads. This paper reclaims the term "mechanotherapy" and presents the current scientific knowledge underpinning how load may be used therapeutically to stimulate tissue repair and remodelling in tendon, muscle, cartilage and bone. The purpose of this short article is to answer a frequently asked question "How precisely does exercise promote tissue healing?" This is a fundamental question for clinicians who prescribe exercise for tendinopathies, muscle tears, non-inflammatory arthropathies and even controlled loading after fractures. High-quality randomised controlled trials and systematic reviews show that various forms of exercise or movement prescription benefit patients with a wide range of musculoskeletal problems.1(-)4 But what happens at the tissue level to promote repair and remodelling of tendon, muscle, articular cartilage and bone? The one-word answer is "mechanotransduction", but rather than finishing there and limiting this paper to 95 words, we provide a short illustrated introduction to this remarkable, ubiquitous, non-neural, physiological process. We also re-introduce the term "mechanotherapy" to distinguish therapeutics (exercise prescription specifically to treat injuries) from the homeostatic role of mechanotransduction. Strictly speaking, mechanotransduction maintains normal musculoskeletal structures in the absence of injury. After first outlining the process of mechanotransduction, we provide well-known clinical therapeutic examples of mechanotherapy-turning movement into tissue healing.
Wet Etching of Doped and Nondoped Silicon Oxide Films Using Buffered Hydrogen Fluoride Solution (1995)

Wet etching of various silicon oxide films using BHF solution was studied as a means of post‐RIE wet cleaning to form small contact holes with the designed shape. Measurements show a dependence of etching rate on concentration for thermal and CVD oxide films. Thermal and ECR‐CVD oxide films showed lower etching rates than doped/nondoped APCVD, LPCVD, and PCVD oxide films showed. The etching rate dependence on concentration was linear for the lower etching rate films but nonlinear for the higher etching rate films. This suggests that, for etching of the higher etching rate films, the dominant etching species is , while plays only a small role.
<title>Frequency-modulation absorption spectroscopy for trace species detection: theoretical and experimental comparison among methods</title> (1991)

Theoretical and practical limits for detection of trace concentrations of gas phase species using frequency modulation spectroscopy are described. A variety of frequency modulation schemes are examined, including wavelength modulation (harmonic detection) spectroscopy (WMS) and one-tone and two-tone frequency modulation spectroscopy (FMS). The distinctions among these methods are mostly semantic and all of these techniques can be described by a single theory. The goal of this research is to define guidelines useful for implementing the optimum modulation technique for specific measurement needs. Applying this formalism, expected sensitivities for each method are compared for selected absorption systems. The results suggest that the choice among techniques is most strongly driven by the individual laser tuning characteristics, the absorption linewidth and the detection bandwidth; no individual method is a priori superior. Results of experimental diode laser measurements which confirm these calculations are presented. Predicted minimum detectable concentrations for a representative variety of gas phase species are also shown.
A highly stretchable and sensitive strain sensor based on graphene–elastomer composites with a novel double-interconnected network (2016)

A facile assembly approach was firstly reported to fabricate a highly stretchable and sensitive strain sensor based on graphene–rubber composites with a novel double-interconnected network.
A simple and effective RF predistorter for use in the HPAs of base stations in cellular mobile systems (2008)

This paper presents the design of using a simple mixer circuit, constructed with Schottky diodes as the nonlinear device, to generate the intermodulation (IM) products for predistortion of high-power amplifiers (HPAs) in the base stations of cellular mobile systems. The design has a simple structure and requires no external dc bias voltage. A complex polynomial is used to model the characteristic of the HPA and the predistorter generates the in-phase and quadrature components of the intermodulation distortion (IMD) products for predistortion of the HPA. Experimental results using a practical HPA show that, for a modulated CDMA (IS-95) signal, the predistorter can reduce the adjacent-channel-power ratio (ACPR) by 15 dB.