gebhart/patrepeval huggingface dataset:
DETECTION OF GSTP1 HYPERMETHYLATION AND HEPSIN ACTIVITY FOR PROSTATE NON-INVASIVE CANCER DIAGNOSTICS (2008)

You have accessJournal of Urology1 Apr 2008DETECTION OF GSTP1 HYPERMETHYLATION AND HEPSIN ACTIVITY FOR PROSTATE NON-INVASIVE CANCER DIAGNOSTICS Evgenia Vasileva, Maria Savvateeva, Ekaterina Kuznetsova, Dmitriy Fiev, Olga Abakumova, Alla Lyashenko, Andrey Vinarov, and Evgeniy Severin Evgenia VasilevaEvgenia Vasileva More articles by this author , Maria SavvateevaMaria Savvateeva More articles by this author , Ekaterina KuznetsovaEkaterina Kuznetsova More articles by this author , Dmitriy FievDmitriy Fiev More articles by this author , Olga AbakumovaOlga Abakumova More articles by this author , Alla LyashenkoAlla Lyashenko More articles by this author , Andrey VinarovAndrey Vinarov More articles by this author , and Evgeniy SeverinEvgeniy Severin More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(08)61999-0AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "DETECTION OF GSTP1 HYPERMETHYLATION AND HEPSIN ACTIVITY FOR PROSTATE NON-INVASIVE CANCER DIAGNOSTICS." The Journal of Urology, 179(4S), p. 685 © 2008 by American Urological AssociationFiguresReferencesRelatedDetails Volume 179Issue 4SApril 2008Page: 685 Advertisement Copyright & Permissions© 2008 by American Urological AssociationMetricsAuthor Information Evgenia Vasileva More articles by this author Maria Savvateeva More articles by this author Ekaterina Kuznetsova More articles by this author Dmitriy Fiev More articles by this author Olga Abakumova More articles by this author Alla Lyashenko More articles by this author Andrey Vinarov More articles by this author Evgeniy Severin More articles by this author Expand All Advertisement PDF downloadLoading ...
Fabrication of Low‐Tortuosity Ultrahigh‐Area‐Capacity Battery Electrodes through Magnetic Alignment of Emulsion‐Based Slurries (2018)

Abstract High energy‐density, low‐cost batteries are critically important to a variety of applications ranging from portable electronics to electric vehicles (EVs) and grid‐scale storage. While tremendous research effort has been focused on new materials or chemistries with high energy‐density potential, design innovations such as low‐tortuosity thick electrodes are another promising path toward higher energy density and lower cost. Growing demand for fast‐charging batteries has also highlighted the need for negative electrodes that can accept high rate charging without metal deposition; low tortuosity can be a benefit in this regard. However, a general and scalable fabrication method for low‐tortuosity electrodes is currently lacking. Here an emulsion‐based, magnetic‐alignment approach to producing thick electrodes (>400 µm thickness) with ultrahigh areal capacity (up to ≈14 mAh cm −2 vs 2–4 mAh cm −2 for conventional lithium ion) is reported. The process is demonstrated for LiCoO 2 and meso‐carbon microbead graphite. The LiCoO 2 cathodes are confirmed to have low tortuosity via DC‐depolarization experiments and deliver high areal capacity (>10 mAh cm −2 ) in galvanostatic discharge tests at practical C‐rates and model EV drive‐cycle tests. This simple fabrication method can potentially be applied to many other active materials to enable thick, low‐tortuosity electrodes.
Analysis of marijuana samples from different origins by high-resolution gas-liquid chromatography for forensic application (1976)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAnalysis of marijuana samples from different origins by high-resolution gas-liquid chromatography for forensic applicationMilos. Novotny, M. L. Lee, Chow-Eng. Low, and Alain. RaymondCite this: Anal. Chem. 1976, 48, 1, 24–29Publication Date (Print):January 1, 1976Publication History Published online1 May 2002Published inissue 1 January 1976https://pubs.acs.org/doi/10.1021/ac60365a039https://doi.org/10.1021/ac60365a039research-articleACS PublicationsRequest reuse permissionsArticle Views592Altmetric-Citations42LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The Protocol Independent Multicast (PIM) Join Attribute Format (2008)

A Protocol Independent Multicast - Sparse Mode Join message sent by
a given node identifies one or more multicast distribution trees that
that node wishes to join. Each tree is identified by the combination
of a multicast group address and a source address (where the source
address is possibly a wild card). Under certain conditions it can be
useful, when joining a tree, to specify additional information related
to the construction of the tree. However, there has been no way to do
so until now. This document describes a modification of the Join
message that allows a node to associate attributes with a particular
tree. The attributes are encoded in Type-Length-Value format.
[STANDARDS-TRACK]
Association Between Systemic Inflammation and Incident Diabetes in HIV-Infected Patients After Initiation of Antiretroviral Therapy (2010)

Inflammatory markers 48 weeks after ART initiation were associated with increased risk of diabetes. These findings suggest that systemic inflammation may contribute to diabetes pathogenesis among HIV-infected patients.
Host-Plant Resistance and Management of Bacterial Spot of Pepper (2008)

PP-255, a 3-page illustrated fact sheet by Ken Pernezny, Jeff Jones, Russell Nagata, and Nikol Havranek, describes the developments in the campaign to develop cultivars resistant to Xanthomonas euvesicatoria. Published by the UF Department of Plant Pathology, June 2008.
Dimensional metrology with the NIST calibrated atomic force microscope (1999)

AFMs are increasingly used in the semiconductor industry as tools for sub-micrometer dimensional metrology. The scale of an AFM must be calibrated in order to perform accurate measurements. We have designed and developed the calibrated AFM (C-AFM) at the NIST to calibrate standards. Specifically, our primary calibrations are expected to be of combined pitch/height, or 3D magnification standards for AFM. THe C-AFM has metrology traceable to the International System of Units meter for all three axes. This is accomplished through the integration of a flexure x-y translation stage, heterodyne laser interferometers, and a z-axis piezoelectric actuator with an integrated capacitance sensor. Our first pitch measurements for an outside customer were recently compete, in which we were able to report relative expanded uncertainties as low as 1 percent on sub- micrometer pitches. The uncertainty budget for these measurements includes the effect of sample non-uniformity, which is the dominant contribution for some of the reported uncertainties. Four samples were measured - two with grid patterns and two with grid recently made considerable improvements in our uncertainty budget for step height measurements. For example, we recently achieved 0.2 nm expanded uncertainty on a 20 nm step, and achieved 0.008 nm expanded uncertainty in the measurement of the approximately 0.3 nm single atom step on Si. We also participated in the recently competed first round of the NIST linewidth correlation project, in which linewidht measurements obtained from different methods are compared. In this paper, we will report on the current status of the C-AFM, and on our plans for further development.
Detecting and preventing the electronic transmission of illicit images (2009)

The sexual exploitation of children remains a very serious problem and is rapidly increasing globally through the use of the Internet. This work focuses on the current methods employed by criminals to generate and distribute child pornography, the methods used by law enforcement agencies to deter them, and the drawbacks of currently used methods, as well as the surrounding legal and privacy issues. A proven method to detect the transmission of illicit images at the network layer is presented within this paper. With this research, it is now possible to actively filter illicit pornographic images as they are transmitted over the network layer in real-time. It is shown that a Stochastic Learning Weak Estimator learning algorithm and a Maximum Likelihood Estimator learning algorithm can be applied against Linear Classifiers to identify and filter illicit pornographic images. In this thesis, these two learning algorithms were combined with algorithms such as the Non-negative Vector Similarity Coefficient-based Distance algorithm, Euclidian Distance, and Weighted Euclidian Distance. Based upon this research, a prototype was developed using the abovementioned system, capable of performing classification on both compressed and uncompressed images. Experimental results showed that classification accuracies and the overhead of network-based approaches did have a significant effect on routing devices. All images used in our experiments were legal. No actual child pornography images were ever collected, seen, sought, or used.
The binding of steroids to myometrium and leiomyomata (fibroids) in women treated with the gonadotrophin-releasing hormone agonist Zoladex (ICI 118630) (1989)

Since uterine leiomyomata (fibroids) are not found in conditions where oestradiol is either absent or present only in low concentrations, oestradiol is considered to be an important factor in the control of fibroid growth. To investigate whether this is due to a direct effect on the tissue, oestradiol and progestogen receptors were measured in tissue removed at hysterectomy from 12 normally cycling women and 13 women who had received the gonadotrophin-releasing hormone (GnRH) agonist Zoladex (ICI 118630) as a subcutaneous depot given at monthly intervals for 3 months preoperatively and a third group of three women who had received the antioestrogen tamoxifen (20 mg daily) for 3 months before surgery. Both unoccupied oestradiol receptors (measured by separating bound from free hormone with dextran-coated charcoal; DCC) and 'total' receptor populations (as measured by an enzyme immunoassay) were measured in each fibroid and adjoining myometrium. There was significantly more binding of both oestradiol and progestogen to fibroid than to myometrium in both the control (P less than 0.01) and agonist-treated groups (P less than 0.05). Oestradiol binding to fibroids in women treated with Zoladex exceeded that in the normally cycling women (P less than 0.05) which in turn exceeded that in the tamoxifen-treated group (P less than 0.05). However, the binding of progestogen, measured by DCC showed the reverse trend. These results may be explained by the low circulating oestradiol concentration in the GnRH agonist-treated women leading to low receptor occupancy.
Characteristics of hematopoietic stem cells of umbilical cord blood (2014)

Umbilical cord blood collected from the postpartum placenta and cord is a rich source of hematopoietic stem cells (HSCs) and is an alternative to bone marrow transplantation. In this review we wanted to describe the differences (in phenotype, cytokine production, quantity and quality of cells) between stem cells from umbilical cord blood, bone marrow and peripheral blood. HSCs present in cord blood are more primitive than their counterparts in bone marrow or peripheral blood, and have several advantages including high proliferation. With using proper cytokine combination, HSCs can be effectively developed into different cell lines. This process is used in medicine, especially in hematology.
Downregulation of Orai1 expression in the airway alleviates murine allergic rhinitis (2012)

Orai1 is the key subunit of the Ca(2+)-release-activated Ca(2+) channel. Our previous report has demonstrated that Orai1 expression in the airway was upregulated in the ovalbumin (OVA)-induced allergic rhinitis (AR) mouse models. To observe whether inhibition of Orai1 expression in the airway could suppress symptoms in a murine model of AR and to assess the impacts of this inhibition on the responses of local and systemic immunocytes, we administered recombinant lentivirus vectors that encoded shRNA against ORAI1 (lenti-ORAI1) into the nostrils of OVA-sensitized mice before the challenges, and analyzed its effect on allergic responses, as compared with the unsensitized mice and untreated AR mice. Administration of lenti-ORAI1 into the nasal cavity successfully infected cells in the epithelial layer of the nasal mucosa, and significantly decreased the frequencies of sneezing and nasal rubbing of the mice. Protein levels of leukotriene C4, OVA-specific IgE, and IL-4 in the nasal lavage fluid and serum and eosinophil cation protein in the serum were also significantly reduced by lenti-ORAI1, as were the mRNA levels of these factors in the nasal mucosa and spleen. These data suggested that administration of lenti-ORAI1 into the nasal cavity effectively decreased Orai1 expression in the nasal mucosa, alleviated AR symptoms, and partially inhibited the hyperresponsiveness of the local and systemic immune cells including T cells, B cells, mast cells and eosinophils that are involved in the pathogenesis of AR.
Activating the Hot Spot Problem by Switching Multiple Sinks in Wireless Sensor Networks (2009)

In many-to-one wireless sensor networks, there exists an unbalanced power consumption problem; that is, nodes near the data sink or base station, called hot spots, have a high probability of forwarding a high amount of packets and die early. Most of previous work is dedicated to constructing a long-lived aggregation tree, while leaving the hot spot problem unsolved. When the locations of sinks are given and thus fixed, this work attempts to alleviate the hot spot problem by exploiting techniques to balance power consumption for nodes in the tree by switching multiple fixed sinks. The first balancing technique is called manipulating multiple long-lived trees (MMLT), which constructs multiple long-lived data aggregation trees for multiple sinks, and cyclically switches a data aggregation tree to another, after a sink collects information for a predefined period of time. To reduce overhead, we further propose another technique which constructs only a single tree and shares it with all sink nodes. To evaluate the performance of these two balancing techniques, we run simulations with various setup environments and compare them with the balanced tree method.
Target manoeuvre detection using radar glint (1998)

A novel target manoeuvre detection system for radar guided homing missiles is described. The system operates by extracting glint noise to detect changes in orientation made as the target manoeuvres. A brief introduction to the detection principle is presented, along with feasibility study results from a fuzzy-logic based implementation.
Gabapentin Successfully Manages Chronic Unexplained Irritability in Children With Severe Neurologic Impairment (2007)

Neurologically impaired children have an increased frequency of recurrent pain and irritability that persist in some despite comprehensive evaluation and management of possible pain sources. We hypothesized that visceral hyperalgesia was a source of chronic unexplained irritability and report the outcome of gabapentin treatment in 9 severely neurologically impaired children. Caregivers reported marked improvement after treatment ranging from 3 months to 3 years. Nystagmus in 1 child was the only noted adverse effect. Visceral hyperalgesia may be a source of unexplained irritability in the neurologically impaired child. Symptoms may improve with gabapentin treatment.
Ultrafast and Continuous Synthesis of Unaccommodating Inorganic Nanomaterials in Droplet- and Ionic Liquid-Assisted Microfluidic System (2011)

Despite many efforts on the synthesis of inorganic nanomaterials with uniform structure and narrow size distribution in a fast and continuous way, it is still a critical challenge in the chemistry research community due to the uncontrollable mass and heat transfer and the harsh experimental conditions of high temperature and pressure. Here we report a droplet- and ionic liquid-assisted microfluidic (DIM) synthesis method, which takes full advantage of both ionic liquids and droplet-assisted microreaction systems, for an ultrafast, mild, and continuous synthesis of various inorganic nanomaterials that takes only tens of minutes rather than days that are usually needed to synthesize. In particular, unaccommodating inorganic nanomaterials that are difficult to produce, such as nanoporous ZSM-5, γ-AlOOH, and β-FeOOH nanorods, were synthesized in only "20 minutes" of reaction time even with simple instrument. The DIM method delineated herein would offer a breakthrough synthetic approach for functional but unaccommodating inorganic nanomaterials in a continuous and mild manner.
Ketamine plus midazolam, a most effective paediatric oral premedicant (1995)

Healthy children, 1.5 to seven years old, were divided into three groups of 20 each. Group 1 received midazolam 0.5 mg.kg-1, Group 2, ketamine 6 mg.kg-1 and Group 3 a mixture of midazolam 0.4 mg.kg-1 + ketamine 4 mg.kg-1. Each dose was mixed with atropine 0.02 mg.kg-1 plus an equal volume of cherry syrup and was given orally 20 to 30 min prior to surgery. A grade of 1 (asleep, difficult to arouse), 2 (asleep, easily aroused), 3 (awake, calm), 4 (awake, anxious, occasional cry), or 5 (crying, agitated), was assigned at the time of parental separation and again when mask induction was begun. A grade of 1-3 was considered successful. For parental separation, the mixture of ketamine+midazolam was 100% successful, ketamine 90% and midazolam 75%. Successful mask induction for the mixture of ketamine+midazolam was 85%, midazolam 65% and ketamine 42%. This study indicates that a mixture of ketamine+midazolam is the most effective.
The isolated resonant modular multilevel converters with large step-ratio for MVDC applications (2017)

The dc-dc conversion will play an important role in multi-terminal dc networks and dc grids. This paper presents two isolated resonant modular multilevel converters (IRMMCs) to fulfill the large step-ratio conversion for medium voltage dc (MVDC) networks. The conventional resonant modular multilevel converters (RMMCs) suffer the common problems of non-isolation and high current stress, which are solved in the proposed IRMMCs. They not only inherit the beneficial features of inherent sub-module (SM) voltage-balancing and soft-switching operation from RMMCs, but also develop multi-module configurations to neutralize the current ripples on both sides of the dc-links. The theoretical analysis is verified by a set of full-scaled simulations for different application examples in MVDC collection and distribution. The results demonstrate the proposed IRMMCs and its derived configurations have good potential for operation as large step-ratio MVDC transformers.
Understanding the Processes Behind Student Designing: Cases from Singapore (2023)

A common perception of designing is that it represents a highly complex activity that is manageable by only a few. However it has also been argued that all individuals are innately capable of designing. Taking up this latter view, we explored the processes behind student designing in the context of Design and Technology (D&T), a subject taught at the Secondary school level in Singapore. We examined the design journey undertaken by two students to understand what designing is like at their level. Case study methodology was adopted to develop a rich data set emerging from the students’ design journals, maps of the students’ design process, and interviews with the students and supervising teachers. The findings revealed that these students had innate capacities to design. Although the approach taken by each student differed, as reflected in visual representations reflecting the design process as well as their commentary, each displayed similar forms of design thinking. That is, both students proposed a novel and innovative solution to their design problem and were able to articulate sound reasoning of their design decisions throughout the entire design process. The supervising teachers enacted a more facilitative pedagogy that supported each student’s design process; this approach differs from traditional pedagogical practices in Singaporean D&T that can be characterised as modelfocused and ‘top down’ in nature.
The Warranty Problem: Its Statistical and Game-Theoretic Aspects (1993)

Manufacturers of consumer products, such as automobiles, usually offer warranties guaranteeing the product or its parts, for example, for five years or 50,000 miles, whichever comes first. There are at least two issues of interest to applied mathematicians and statisticians that arise from warranty considerations. The first is the specification of an optimum price-warranty combination, and the second is the forecast of a reserve fund to meet warranty claims against the product. The former involves a consideration of the item’s reliability, its rate of usage, the consumer’s attitude toward a specific warranty, and the competitor’s actions, all of which lead towards a game theoretic formulation of the problem. The latter involves the analysis of a special kind of time series in two-dimensions, for which the use of dynamic linear models appears to be natural. This is an expository paper. Due to the timeliness of the topic, the focus here is on problem definition, its scope, and its formulation in a manner that facilitates analysis. Imbedded in the discussion are strategies for addressing some of the ensuing issues. The overall goal is to enlighten the reader about an area of research in the mathematical sciences that has an impact on industrial competitiveness and the manufacturing sciences.
Interpleural catheter technique for perioperative pain management. (2006)

Management of pain in surgical patient is very crucial. It is more so in thoracic and upper abdominal surgery. Lots of technique and drugs have been used to control postoperative pain including thoracic epidural analgesia. We describe a case in whom Intraoperative and Postoperative pain was managed by injecting 0.5% bupivacaine 20 ml in the interpleural space through the catheter, followed by continuous infusion of 0.1% bupivacaine 10 ml/ hour for 24 hours. The whole perioperative and postoperative period was uneventful. The first series of patients in whom this technique was used was described by Murphy in 1983, (1) who used it in patients with multiple fractured ribs and in postoperative patients after gallbladder and kidney surgery. One year later, Reiestad and Kvalheim published their results of continuous intercostal nerve block for postoperative pain relief and presented their modification of the technique, which is now termed interpleural analgesia.