gebhart/patrepeval huggingface dataset:
Effect of Pre-Germination Time on Amino Acid Profile and Gamma Amino Butyric Acid (GABA) Contents in Different Varieties of Malaysian Brown Rice (2010)

Eighteen varieties of Malaysian brown rice were evaluated for their crude protein, total glutamic acid, and gamma amino butyric acid contents after pre-germination at different times. The crude protein and total glutamic acid content increased significantly in all the varieties after pre-germination. Gamma amino butyric acid content increased dramatically with time during the pre-germination process. A significant (p < 0.05) positive correlation was observed between protein, glutamic acid, and gamma amino butyric acid contents before and after pre-germination. The brown rice varieties containing higher glutamic acid and/or protein content before the pre-germination process provided more gamma amino butyric acid content during pre-germination.
Prolactin Binds to Human Endometrial Fibroblasts and Inhibits Mitogenicity of an Endometrial Carcinoma Extract (1993)

Uterine endometrial carcinoma has been reported to synthesize and secrete a putative peptide mitogen that elicits a potent proliferative response in endometrial fibroblasts. The extract from endometrial carcinoma stimulated [3H]thymidine incorporation into human endometrial fibroblasts in a dose-dependent manner. Concomitant exposure of the fibroblasts to prolactin (PRL) led to a remarkable inhibition of the extract-stimulated mitogenic activity of the fibroblasts. This inhibition was dependent on PRL dose, and maximal effect occurred at 1 μM of PRL. PRL (10 nM) suppressed an apparent maximal activity of the extract by 50%, and the half-maximal stimulated effect of the extract on thymidine incorporation was observed at the same concentration in the absence or presence of PRL. This noncompetitive manner may imply that PRL acts at a stage after the interaction of the mitogen in the extract with the specific receptor for mitogen. When the fibroblasts were first exposed to the extract for 12 hr and then to PRL, PRL suppressed the mitogenic activity with no lag. The rapid growth-inhibitory effect of PRL was mimicked by prostaglandin E1, but the combination of both types of ligand was not additive in the inhibitory action on growth. PRLand prostaglandin E1 may inhibit a similar mitogenic signaling cascade. Specific receptor sites for PRL were detected in the endometrial fibroblasts, showing high binding affinity (Kd =16.1 nM) and low binding capacity (Bmax = 1.59 pmol/mg protein). Treatment of the fibroblasts with the endometrial carcinoma extract induced no changes in the level of PRLreceptor, excluding the possibility that PRL competes for the binding sites with the mitogen. These findings would suggest that PRL may block the mitogenic activity of the fibroblasts stimulated by the endometrial carcinoma-derived mitogen via a PRL receptor-mediated mechanism, perhaps prostaglandin production.
Impacts of China’s growth on the Brazilian trade (2011)

We evaluate whether the presence of China in world trade is ultimately beneficial or whether it is a threat to Brazil. Using a gravitational model and a panel data method, we find that the Chinese exports to countries other than Brazil are not hurting the Brazilian exports, although the exports of Brazilian manufactured goods have been displaced by commodities as a result of its commerce with China.
Periodically refreshed multiply exposed photorefractive holograms (1990)

We describe a method for increasing the diffraction efficiency of multiply exposed photorefractive holograms by periodic copying. The method is experimentally demonstrated with photorefractive and thermoplastic recording media.
Virtual reality and telepresence: visual worlds from non-visual sensors (1991)

The Teletact glove system, the high-speed pan-and-tilt system, and the Vision graphics engine are described. The VERDEX test bed is being used in the short term to carry out experimental studies of human performance during and after immersion in a virtual world. Studies planned include a comparactive investigation of speech recognition and gesture control for motion through a virtual world and interaction with virtual objects, and a psycho-physiological study of medium- and long-term immersion.
Engineering domain configurations for enhanced piezoelectricity in barium titanate single crystals (2006)

In this letter, we propose a mechanism for enhanced piezoelectricity that takes advantage of both intrinsic crystalline anisotropy of ferroelectric crystal and extrinsic 90° domain switching of ferroelectric variant. The domain configurations we consider here are not clamped, and thus allow domain switching driven by the competition between external electric field and internal depolarization field. The intrinsic and extrinsic piezoelectric responses of barium titanate single crystals under different crystallographic orientations are calculated using an energy minimization theory, where it is observed that the piezoelectric coefficient is significantly enhanced by the 90° domain switching, especially under the small field measurement where the domain wall movement is reversible, which is consistent with recent experimental observations. The optimal crystallographic orientation is also identified.
Query Prediction in Large Scale Data Intensive Event Stream Analysis Systems (2008)

Hot-spot events accessing has recently received considerable attentions in the event stream historical analysis systems. Noting that predicates in SQL (Structured Query Language) requests usually have similarity features in a short time in event stream systems, that means events frequently queried recently might be queried again in the near future. This paper proposes a prediction model to forecast query predicates and then to choose them for speculative execution. We propose an adaptive two-level scoring (TLS) prediction algorithm, which can adjust parameters according to the system resource usage conditions. We introduce two metrics accuracy rate and efficiency rate, for query prediction evaluation, and make a detailed analysis of system costs. Our experimental results in DBroker system demonstrate the TLS algorithm and local speculative execution method can significantly reduce query response time.
Structural Analysis of a Lotus japonicus Genome. II. Sequence Features and Mapping of Sixty-five TAC Clones Which Cover the 6.5-Mb Regions of the Genome (2002)

Sixty-five TAC (transformation-competent artificial chromosomes) clones were selected from a genomic library of Lotus japonicus accession MG-20 based on the sequence information of expressed sequences tags (ESTs), cDNA and gene information, and their nucleotide sequences were determined. The average insert size of the TAC clone was approximately 100 kb, and the total length of the sequenced regions in this study is 6,556,100 bp. Together with the nucleotide sequences of 56 TAC clones previously reported, the regions sequenced so far total 12,029,295 bp. By comparison with the sequences in protein and EST databases and by analysis with computer programs for gene modeling, a total of 711 potential protein-encoding genes with known or predicted functions, 239 gene segments and 90 pseudogenes were identified in the newly sequenced regions. The average gene density assigned so far was 1 gene/9140 bp. The average length of the assigned genes was 2.6 kb, which is considerably larger than that assigned in the Arabidopsis thaliana genome (1.9 kb for 6451 genes). Introns were identified in approximately 73% of the potential genes, and the average number and length of the introns per gene were 3.4 and 377 bp, respectively. Simple sequence repeat length polymorphism (SSLP) or derived cleaved amplified polymorphic sequence (dCAPS) markers were generated based on the nucleotide sequences of the genomic clones obtained, and each clone was mapped onto the linkage map using the F2 mapping population derived from a cross of two accessions of L. japonicus, Gifu B-129 and Miyakojima MG-20. The sequence data, gene information and mapping information are available through the World Wide Web at http://www.kazusa.or.jp/lotus/.
Multiple Initiations in the <i>c-myc</i> Replication Origin Independent of Chromosomal Location (1998)

At supramolecular resolution, DNA synthesis begins at preferred replication origins in the chromosomes of metazoan cells. To characterize one of these origins in detail, the initiation of replication was examined in the HeLa c-myc origin. Polymerase chain reaction (PCR) amplification of size-fractionated nascent chromosomal DNAs revealed multiple replication initiation sites over a 12-kb region spanning the c-myc origin, including the transcribed region and the 5' and 3' flanking DNA of the gene. Two of the start sites for chromosomal replication occurred inside a 2.4-kb region of the origin that exhibits autonomously replicating sequence (ARS) activity. When a plasmid containing the 2.4-kb ARS region was transfected into HeLa cells, PCR mapping of nascent plasmid DNA confirmed that the plasmid replicated semiconservatively and autonomously and that replication did not initiate at random sites but rather began at multiple sites in a limited zone overlapping the c-myc DNA insert. Within the resolution of the PCR assay, the same sites that were used in the chromosomal c-myc origin were used in the 2.4-kb ARS fragment. The locations of replication start sites determined by PCR are considered in the context of other functional and structural elements of the c-myc origin.
Prediction and verification of mouse tRNA gene families (2009)

These confirmed tRNA genes represent all anticodons and all known mammalian tRNA structural groups, as well as a variety of predicted "rogue" tRNA genes within families with altered anticodon identities.
An Integrated Phase Change Memory Cell With Ge Nanowire Diode For Cross-Point Memory (2007)

We demonstrate a novel phase change memory cell utilizing doped Ge nanowire pn-junction diode both as a bottom electrode and a memory cell selection device. This memory cell can be used for a cross-point memory array with diode selection. Using selective growth of isolated vertical nanowires in each cell, we have minimized the contact area below the lithography limit. A very low SET programming current of 10's of μA was achieved. RESET/SET resistance ratio of 100x was obtained. The diode provides 100x isolation between forward and reverse bias in the SET state.
Asymptotic performance analysis of ESPRIT, higher order ESPRIT, and virtual ESPRIT algorithms (1996)

In this paper, we present an asymptotic performance analysis of three subspace-based methods for direction of arrival (DOA) estimation-the ESPRIT algorithm using second order statistics, the higher order ESPRIT algorithm using fourth-order cumulants, and the virtual ESPRIT (VESPA) algorithm using fourth-order cumulants. We examine the least-squares version of these algorithms, derive the expressions for the asymptotic variance of the estimated DOAs, and use specific examples to compare the relative performance of the algorithms. Finally, we present Monte Carlo simulations to validate the theoretical analysis.
Molecular analysis of a UDP-GlcNAc:polypeptide α-N-acetylglucosaminyltransferase implicated in the initiation of mucin-type O-glycosylation in Trypanosoma cruzi (2009)

Trypanosoma cruzi, the causative agent of Chagas disease, is surrounded by a mucin coat that plays important functions in parasite survival/invasion and is extensively O-glycosylated by Golgi and cell surface glycosyltransferases. The addition of the first sugar, alpha-N-acetylglucosamine (GlcNAc) linked to Threonine (Thr), is catalyzed by a polypeptide alpha-GlcNAc-transferase (pp-alphaGlcNAcT) which is unstable to purification. Here, a comparison of the genomes of T. cruzi and Dictyostelium discoideum, an amoebazoan which also forms this linkage, identified two T. cruzi genes (TcOGNT1 and TcOGNT2) that might encode this activity. Though neither was able to complement the Dictyostelium gene, expression in the trypanosomatid Leishmania tarentolae resulted in elevated levels of UDP-[(3)H]GlcNAc:Thr-peptide GlcNAc-transferase activity and UDP-[(3)H]GlcNAc breakdown activity. The ectodomain of TcOGNT2 was expressed and the secreted protein was found to retain both activities after extensive purification away from other proteins and the endogenous activity. Product analysis showed that (3)H was transferred as GlcNAc to a hydroxyamino acid, and breakdown was due to hydrolysis. Both activities were specific for UDP-GlcNAc relative to UDP-GalNAc and were abolished by active site point mutations that inactivate a related Dictyostelium enzyme and distantly related animal pp-alphaGalNAcTs. The peptide preference and the alkaline pH optimum were indistinguishable from those of the native activity in T. cruzi microsomes. The results suggest that mucin-type O-glycosylation in T. cruzi is initiated by conserved members of CAZy family GT60, which is homologous to the GT27 family of animal pp-alphaGalNAcTs that initiate mucin-type O-glycosylation in animals.
Examining Discourse When Talking with Women (2005)

This paper discusses the ongoing responsibility we have as therapists for opening spaces to examine cultural and social conditions that can easily remain invisible. The author asks: 'How can I step outside my own ideology and question it', and 'What steps can I take to expand the range of discourses which are brought into therapeutic conversations?' A postmodern feminist orientation is discussed as a way to examine and explore the dominant discourses which are powerfully shaping of identity. Through the story of Rosanna's life we see how these explorations are linked with re-authoring conversations.
A Systematic Mapping Study on Service Oriented Computing in the Context of Quality of Services (2013)

Background: In the last years, the field of service oriented computing (SOC) has received a growing interest from researchers and practitioners, particularly with respect to quality of service (QoS).Aim: This paper presents a mapping study to aggregate literature in this field in order to find trends and research opportunities regarding QoS in SOC.Method: Following well established mapping study protocol, we collected data from major digital libraries and analysed 364 papers aided by a tool developed for this purpose.Results: With respect to SOC contributions dealing with QoS properties, we were able to find out which SOC as well as which QoS facets are the focus of research. Our mapping was also able to identify those research groups that have mostly published in the context of our study. Conclusions: Most of the studies concentrate on runtime issues, such as monitoring and adaptation. Besides, an expressive amount of papers focused on metrics, computational models or languages for the context of Qos in SOC. Regarding quality attributes, a vast majority of the papers use generic models, so that the proposed solutions are independent of the particularities of a quality attribute. In spite of that, our study reveal that availability, performance and reliability were the major highlights. With respect to research type, many of the reviewed studies propose new solutions, instead of evaluating and validating existing proposals -- a symptom of a field that still needs established research paradigms.
Isolation and nucleotide sequence of the gene encoding cytotoxic necrotizing factor 1 of Escherichia coli (1993)

Cytotoxic necrotizing factors (CNFs) are dermonecrotic protein toxins produced by human and animal clinical isolates of Escherichia coli. In this study, the CNF1 determinant was isolated and sequenced, showing that expression of biologically active toxin is governed by a unique open reading frame encoding a protein of 1,014 amino acids with a predicted molecular mass of 113.7 kDa. Nucleotide and protein data base searches showed significant homology between CNF1 and the dermonecrotic toxin of Pasteurella multocida. In particular, the two toxins were found to share a hydrophobic region of about 220 amino acids which is a potential membrane-spanning domain.
A Karhunen-Loeve-like expansion for 1/f processes via wavelets (1990)

While so-called 1/f or scaling processes emerge regularly in modeling a wide range of natural phenomena, as yet no entirely satisfactory framework has been described for the analysis of such processes. Orthonormal wavelet bases are used to provide a new construction for nearly 1/f processes from a set of uncorrelated random variables.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Exploratory landscape analysis (2017)

tutorial Share on Exploratory landscape analysis: advanced tutorial at GECCO 2017 Authors: Pascal Kerschke University of Münster, Germany University of Münster, GermanyView Profile , Mike Preuss University of Münster, Germany University of Münster, GermanyView Profile Authors Info & Claims GECCO '17: Proceedings of the Genetic and Evolutionary Computation Conference CompanionJuly 2017 Pages 762–781https://doi.org/10.1145/3067695.3067696Published:15 July 2017Publication History 2citation134DownloadsMetricsTotal Citations2Total Downloads134Last 12 Months12Last 6 weeks3 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Role of Weathered Coal Tar Pitch in the Partitioning of Polycyclic Aromatic Hydrocarbons in Manufactured Gas Plant Site Sediments (2006)

Polycyclic aromatic hydrocarbons (PAHs) in manufactured gas plant (MGP) site sediments are often associated with carbonaceous particles that reduce contaminant bioavailability. Although black carbon inclusive partitioning models have been proposed to describe elevated PAH partitioning behavior, questions remain on the true loading and association of PAHs in different particle types in industrially impacted sediments. In the studied MGP sediments, the light density organic particles (coal, coke, wood, and coal tar pitch) comprised 10-20% of the total mass and 70-95% of the PAHs. The remainder of the PAHs in sediment was associated with the heavy density particles (i.e., sand, silt, and clays). Among the different particle types, coal tar pitch (quantified by a quinoline extraction method) contributed the most to the bulk sediment PAH concentration. Aqueous partition coefficients for PAHs measured using a weathered pitch sample from the field were generally an order of magnitude higher than reported for natural organic matter partitioning, and match well with theoretical predictions based on a coal tar-water partitioning model. A pitch-partitioning inclusive model is proposed that gives better estimates of the measured site-specific PAH aqueous equilibrium values than standard estimation based on natural organic matter partitioning only. Thus, for MGP impacted sediments containing weathered pitch particles, the partitioning behavior may be dominated by the sorption characteristics of pitch and not by natural organic matter or black carbon.
Linguistic Diversity and Plurality in North America (2020)

Linguistic diversity and plurality in contemporary North America is shaped by the continent's history of colonization by Britain, France, and Spain, European settlement, the genocide and forced assimilation of indigenous populations resulting in the decimation of the vast diversity of Native North American languages, and involuntary and voluntary migration of peoples from across global contexts. The majority language of contemporary North America is English, spoken either monolingually, or in addition to French, Spanish, or other minority languages. But despite English's hegemony, linguistic diversity persists in the range of languages spoken as well as regional and ethnic variation present within language groups. Language use in North America is shaped by the tensions between nationalist ideologies of linguistic homogeneity and laws and practices that foster plurality in the form of linguistic and cultural self‐determination and preservation for indigenous peoples, immigrant groups, and regional and ethnic minority groups.
The Future of Antibiotics and Resistance (2013)

Antibiotic resistance and the collapse of the antibiotic research-and-development pipeline continue to worsen despite our ongoing efforts. If we're to develop countermeasures that have lasting effects, new ideas that complement traditional approaches are needed.
Main features of 5G New Radio for Non-Terrestrial Networks (2021)

As the non-terrestrial networks can provide a wide range of service coverage and the vulnerability of the spaceborne or airborne platform is reduced, interest in providing 5G service using the non-terrestrial networks has been increasing. To benefit from the economies of scale of the 5G ecosystem, interest in integration of the non-terrestrial networks (NTN) into the terrestrial networks has been growing. Integration with the existing terrestrial networks can also provide global connectivity and communications resiliency. Standardization efforts to integrate NTN into the 3rd generation partnership project (3GPP) ecosystem have been ongoing. In this paper, we provide an overview of the state of the art in the non-terrestrial networks working on the 3GPP. Furthermore, we analyze technical challenges, solutions and remaining issues dealing in 3GPP NTN regarding to two main characteristics of the long propagation delay and fast movement of NTN platforms. Finally, our views on 6G standardization towards realization of three-dimensional spatial networks are presented.
Effects of Substance P and Other Peptides on the Release of Somatostatin, Insulin, and Glucagon in Vitro* (1980)

We studied the actions of substance P, bombesin, vasoactive intestinal peptide (VIP), and the octapeptide of cholecystokinin (CCK-8-S) on the release of somatostatin, insulin, and glucagon from the isolated perfused pancreatico-duodenal canine preparation. Substance P at concentrations ranging from 0.2-5.0 nM stimulated the secretion of somatostatin, insulin, and glucagon in a dose-dependent manner. However, the responses evoked by substance P were modified by the prevailing glucose level; higher somatostatin and insulin and lower glucagon responses were obtained at the high glucose concentration of 8.3 mM rather than at the low glucose concentration of 2.8 mM. At a glucose concentration of 5.5 mM, somatostatin release was above the prestimulation level in response to 1 nM substance P (89 +/- 15%; P less than 0.01), VIP (49 +/- 7%; P less than 0.01), or CCK-8-S (99 +/- 21%; P less than 0.01); bombesin was without effect (16 +/- 14; P = NS). Insulin release was enhanced by substance P (150 +/- 45%; P less than 0.05), bombesin (162 +/- 56%; P less than 0.05), VIP (44 +/- 5%; P less than 0.01), and CCK-8-S (190 +/- 17%; P less than 0.001). Furthermore, a significant release of glucagon was evoked by 1 nM substance P (501 +/- 158%; P less than 0.05), bombesin (30 +/- 10%; P less than 0.05), VIP (43 +/- 8%; P less than 0.01), or CCK-8-S (140 +/- 19%; P less than 0.001).