gebhart/patrepeval huggingface dataset:
An all-digital phase-locked loop for high-speed clock generation (2003)

An all-digital phase-locked loop (ADPLL) for high-speed clock generation is presented. The proposed ADPLL architecture uses both a digital control mechanism and a ring oscillator and, hence, can be implemented with standard cells. The ADPLL implemented in a 0.3-μm one-poly-four-metal CMOS process can operate from 45 to 510 MHz and achieve worst case frequency acquisition in 46 reference clock cycles. The power dissipation of the ADPLL is 100 mW (at 500 MHz) with a 3.3-V power supply. From chip measurement results, the P/sub k/-P/sub k/ jitter of the output clock is <70 ps, and the root-mean-square jitter of the output clock is <22 ps. A systematic way to design the ADPLL with the specified standard cell library is also presented. The proposed ADPLL can easily be ported to different processes in a short time. Thus, it can reduce the design time and design complexity of the ADPLL, making it very suitable for system-on-chip applications.
O lugar de Otto Maria Carpeaux no campo da crítica (2011)

EnglishThe paper studies Otto Maria Carpeaux`s work in the context of Brazilian literary critic in the decades of 1940-1950. Starting from Pierre Bourdieu`s theoretical formulations about field concept, are set reflections concerning the place occupied by Carpeaux in the light of paradigm shifts occurred in the criticism field and new processes of legitimation resulting from this situation. Two hypotheses developed in this study are: a) Carpeaux`s work was affected by a lack of legitimacy of his contemporaries in the decades of 1940-1950, as can be seen, for example, in peripheral treating conferred on him by the field of diffusion and consecration instances - we can read, the editorial market. b) Carpeaux such as an Alvaro Lins`s heir in the Correio da Manha, also inherited a criticism model that lost prestige in the light of the New Criticism growing influence occurred in the country, which shifts the critical role from the newspaper to the university portuguesO artigo estuda a obra de Otto Maria Carpeaux no contexto da critica literaria brasileira nas decadas de 1940-1950. Partindo das formulacoes teoricas de Pierre Bourdieu sobre o conceito de campo, sao estabelecidas reflexoes sobre o lugar ocupado por Carpeaux em funcao das mudancas de paradigma ocorridas no campo da critica e dos novos processos de legitimacao dai decorrentes. Duas hipoteses sao desenvolvidas neste estudo: a) a obra de Carpeaux sofreu os efeitos da falta de legitimidade de seus contemporâneos nas decadas de 1940-1950, o que pode ser observado, por exemplo, no tratamento periferico a ele conferido pelo campo das instâncias de difusao e consagracao - leia-se mercado editorial. b) herdeiro de Alvaro Lins no Correio da Manha, Carpeaux herda tambem um modelo de critica que perde prestigio em funcao da influencia crescente do New Criticism no pais, que desloca o eixo de atuacao da critica do jornal para a universidade
Damage Radius Study of Gimbaled Forward-Firing Warhead to Tactical Ballistic Missile (2013)

Gimbaled forward-firing warhead (GFFW) is one of the most efficient types for killing enhancement that exist today. This is because almost all the fragments of the warhead are deployed to the targets direction. Static explosion experiment was performed to investigate the spatial distribution of the spray pattern as well as its deployment velocity. The cone angle (θ s ) of fragments bundle at static conditions is 15°, and fragments in the mesial area is dense than that in the marginal area. The average velocity of the fragment in mesial area is 1712m/s, and that in marginal area is 1408m/s. In conjunction with deployment experiments, damage radius study is conducted with the basic criterion that one fragment must hit target payload at least. Damage radius at the dynamic conditions is 150m~165m, which is more farther than conventional uniform warhead.
Modeling Pre-Existing Immunity to Adenovirus in Rodents: Immunological Requirements for Successful Development of a Recombinant Adenovirus Serotype 5-Based Ebola Vaccine (2013)

Pre-existing immunity (PEI) to human adenovirus serotype 5 (Ad5) worldwide is the primary limitation to routine clinical use of Ad5-based vectors in immunization platforms. Using systemic and mucosal PEI induction models in rodents (mice and guinea pigs), we assessed the influence of PEI on the type of adaptive immune response elicited by an Ad5-based vaccine for Ebola with respect to immunization route. Splenocytes isolated from vaccinated animals revealed that immunization by the same route in which PEI was induced significantly compromised Ebola Zaire glycoprotein (ZGP)-specific IFN-γ+ CD8+ T cells and ZGP-specific multifunctional CD8+ T cell populations. ZGP-specific IgG1 antibody levels were also significantly reduced and a sharp increase in serum anti-Ad5 neutralizing antibody (NAB) titers were noted following immunization. These immune parameters correlated with poor survival after lethal challenge with rodent-adapted Ebola Zaire virus (ZEBOV). Although the number of IFN-γ+ CD8+ T cells was reduced in animals given the vaccine by a different route from that used for PEI induction, the multifunctional CD8+ T cell response was not compromised. Survival rates in these groups were higher than when PEI was induced by the same route as immunization. These results suggest that antigen-specific multifunctional CD8(+) T cell and Th2 type antibody responses compromised by PEI to Ad5 are required for protection from Ebola. They also illustrate that methods for induction of PEI used in preclinical studies must be carefully evaluated for successful development of novel Ad5-based vaccines.
Drone detection and tracking based on phase-interferometric Doppler radar (2018)

In this paper, drone detection and tracking based on phase-interferometry are investigated. Data collected by a simple dual-channel Doppler radar is used for implementing the joint range-Doppler-azimuth processing. Experimental results show that micro drones can be detected and tracked by applying the joint range-Doppler-azimuth processing. Features extracted from the range-Doppler-azimuth domain can be used to identify drones.
Questions for Artificial Intelligence in Health Care (2018)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
On the Use of Torque-Biasing Systems for Electronic Stability Control: Limitations and Possibilities (2007)

This brief paper focuses on the concept of utilizing torque-biasing systems on a four-wheel drive vehicle for improving vehicle stability and handling performance. In contrast to brake-based yaw stability control systems, torque biasing has the potential to provide yaw stability control without slowing down the longitudinal response of the vehicle. An inexpensive system configuration is considered in which the driveline is based on front-wheel drive with on-demand transfer of torque to the rear. The torque-biasing components of the system are an electronically controlled center coupler and a rear electronically controlled limited slip differential. First, modeling of the torque-biasing devices is briefly introduced. Then, a hierarchical control architecture is presented in which an upper controller determines desired yaw moment for achieving yaw rate and slip angle control. The lower controller attempts to achieve the desired yaw moment using torque biasing. Theoretical analysis shows that transfer of longitudinal tire forces can effectively be used to achieve any desired yaw moment for the vehicle. However, the use of torque biasing cannot always achieve the desired transfer of longitudinal tire forces. Simulations show that the proposed control system can always effectively provide understeering yaw moments but can provide oversteering torque moments only during on-throttle maneuvers. Experimental data show that significant stability improvements are obtained using the proposed system for low-friction slalom maneuvers and a T-junction launch maneuver. The results presented in this brief shed important light on the possibilities and limitations of using torque biasing for vehicle yaw stability control
Development of Smart Shift and Drive Control System Based on the Personal Driving Style Adaptation (2016)

<div class="section abstract"><div class="htmlview paragraph">In general, driving performance is developed to meet preference of average customers. But there is no single standardized guideline which can satisfy various driving tastes of all drivers whose gender, cultural background, and age are different. To resolve this issue, automotive companies have introduced drive mode buttons which drivers can manually select from Normal, Eco, and Sport driving modes. Although this multi-mode manual systems is more efficient than single-mode system, it is in a transient state where drivers need to go through troubles of frequently selecting their preferred drive mode in volatile driving situations It is also doubtful whether the three-categorized driving mode can meet complex needs of drivers.. In order to settle these matters, it is necessary to analyze individual driving style automatically and to provide customized driving performance service in real time. In this paper, we adopted fuzzy algorithm to evaluate user’s short- and long-term driving tendency by analyzing various vehicle signals. We also came with a result of developing a smart shift and drive control system capable of changing power train and chassis control based on personal driving style and road condition to provide drivers with optimal driving performance and experiences.</div></div>
NLOS error mitigation based on modified Kaiman filter for mobile location in cellular networks (2010)

Non-line-of-sight (NLOS) propagation biases Time of Arrival (TOA) and Time Difference of Arrival (TDOA). It causes the principal error for the mobile location in cellular networks. To mitigate the positioning error, a mobile positioning approach based on modified Kalman filter is proposed in this paper. With this approach, the true range is estimated based on the measurements, and the estimated range is utilized to location solution, which can reduce the impact of NLOS effectively. In our approach, the modified Kalman filter adapt its parameters with the estimate of NLOS's standard deviation, which make the approach remain effective in different environments. Simulation results show that this approach presents a good positioning accuracy even under NLOS propagation environments. The approach can be well applicable to mobile location in cellular networks.
Technological challenges on the road toward transparent networking (2008)

The sustainable growth of high-bandwidth services and on-demand applications has introduced new challenges to next-generation networks in terms of capacity, configurability, and resiliency. Significant networking advancements need to be achieved with architectures and technologies that are scalable with respect to cost, size, and power requirements, while they should be capable of handling high traffic volumes and dynamically changing connection patterns. Transparent networking has the potential to meet those requirements and offer significant benefits in terms of performance and cost. We present the key enabling technologies, review the state-of-the-art achievements, and discuss the new opportunities that optical transparency has and will introduce.
Organic negative-resistance devices using PPV containing electron-transporting groups on the main chain (2001)

A kind of novel structure polymer, a poly(phenylenevinylene) (PPV) derivative containing electron-transporting groups on the main chain (OPPV), was developed according to the polycondensation mechanism. The I–V characteristics at the low-voltage region with negative differential resistance were observed in the same model of organic light-emitting diodes with the OPPV polymer. The different external parameters, including the device structure, layer thickness, morphology, and homogeneity of indium tin oxide and the polymer, were also investigated. The performance improvement in the organic negative differential resistance and a possible mechanism are discussed. © 2001 John Wiley & Sons, Inc. J Polym Sci B: Polym Phys 39: 589–593, 2001
In Vivo Tumor Response End Points (2002)

The field of cancer research is very fortunate, because only recently has it come the forefront of human scientific endeavor, allowing cancer to take advantage of the experience of others. Before the organized investigation of malignant disease, researchers had worked out scientific methodology and recognized the importance of laboratory models for infectious diseases, allowing rapid progress in antibacterial drug development. Cancer research has also benefited from the early research of the 1950s and 1960s, which took a very orderly and rigorously scientific approach to the development of in vivo models and to the development of the most informative end points available from their experiments.
Evaluación de mezclas asfálticas reciclables con aditivos: Una alternativa de reducción de impactos económicos y ambientales (2016)

This research project is a contribution, from an academic point of view, to the use of new asphalt mixtures aimed at solving priority needs in road network maintenance. Its main goal was the evaluation of four asphalt mixtures [MDC - 19], via the Marshall method, using recycled material from planed pavement [RAP] with variations in the content of the mixture. The pre-experimental stage included laboratory testing for the characterization of the components of the design mixes, in accordance with the standards set by the National Roads Institute; the experimental phase evaluated the mixture with regard to the dynamic module, the resistance to distortion due to fatigue and the adhesion. According to the results we determined that the optimum amount of asphalt increases according to the relation of RAP content in the mixture and there was evidence of an improvement of the same regarding resistance and distortion; moreover, the study validated as satisfactory the use of the rejuvenating additive material in the recycled RAP material which allows us to confirm that the additive significantly improved the conditions of the asphalt.
Next Generation Mobile Fronthaul and Midhaul Architectures [Invited] (2015)

Centralized processing is expected to bring about substantial benefits for wireless networks both on the technical side and on the economic side. While this concept is considered an important part of future radio access network architectures, it is more and more recognized that the current approach to fronthauling by employing the Common Public Radio Interface protocol will be inefficient for large-scale network deployments in many respects, and particularly for the new radio network generation 5G. In this paper, an overview is given of currently available optical fronthaul technologies, and of recently started activities toward more efficient and scalable solutions, and finally an outlook is given into which 5G specific service characteristics may further impact future backhaul, midhaul, and fronthaul networks.
Dip-coated sheet silicon solar cells (1976)

A cost-effective method is being developed for producing solar cell quality sheet silicon by dip coating inexpensive ceramic substrates with a thin layer of large grain silicon. Mullite (Aluminum Silicate) ceramic substrates coated with a thin layer of graphite have been dipped into molten silicon to produce 20-150 micron thick layers having grain sizes as large as .4 cm x 4 cm. With these silicon layers photovoltaic diodes have been fabricated with measured and inherent conversion efficiencies of 4% and 7%, respectively.
Programmable protein–protein conjugation via DNA-based self-assembly (2012)

Protein molecules were precisely arrayed on a designable DNA scaffold close to each other using a DNA aptamer. By adding a chemical cross-linker, the neighboring protein molecules were effectively and covalently cross-linked to each other without losing their activities.
Upregulation of Interleukin-4 and IFN-gamma Expression by IFN-tau, a Member of the Type I IFN Family (1999)

Trophoblast interferon-tau (IFN-tau) is a new member of the type I IFN family that is produced in large quantities by the ruminant conceptus. Like other type I IFN, IFN-tau inhibits viral replication and activates natural killer (NK)-mediated cytotoxicity. In mice and humans, type I IFN enhances type 1 T helper (Th) cell responses, but the effects of type I IFN, including IFN-tau, on cytokine expression by bovine Th cells have not been described. The present study determined the effects of IFN-tau on interleukin-4 (IL-4), IFN-gamma, and IL-10 expression by antigen-specific, CD4+ T cell lines derived from cattle immune to either Babesia bovis, Babesia bigemina rhoptry-associated protein-1, or Anaplasma marginale. IFN-tau upregulated IFN-gamma secretion and steady-state levels of IFN-gamma and IL-4 mRNA by cell lines cultured for 3-6 weeks. In contrast, the steady-state levels of IL-10 mRNA were either not changed or inhibited at these times. Similar effects were obtained with human IFN-alpha. Comparison of the quantities of IFN-gamma, IL-4, and IL-10 transcripts in IFN-tau-treated or IFN-alpha-treated cultures revealed that even though IFN-gamma was the predominant cytokine expressed by all T cell lines, both IFN-gamma and IL-4 steady-state transcript levels were upregulated by a comparable degree. Thus, these studies demonstrate that IFN-tau is an immunomodulatory cytokine that promotes enhanced IL-4 and IFN-gamma responses by effector T cells but not, strictly speaking, Thl-biased responses in cattle. These results indicate the potential use of this cytokine as an adjuvant in ruminants to boost cell-mediated immune responses.
Transgenic Mouse Model to Study the Role of EGF Receptor in Breast Cancer (1999)

Abstract : Epidermal growth factor (EGF) receptor is expressed in many normal tissues, including mammary epithelium. Overexpression or mutation of the EGF receptor causes neoplastic transformation in many cell types. Several studies have implicated the EGF receptor as a good prognostic marker in breast cancer, but its role in the etiology and progression of this malignancy is still under dispute. We propose to utilize a genetic approach to investigate this issue, by developing transgenic mice in which the EGF receptor gene in the mammary gland will be inactivated at the onset of the first lactation. The construct for the gene targeting was made and was introduced into the ES cells. Positive clones by Southern blot analysis were injected to generate chimeric mice. Germline transmission from those chimeric animals were also generated. Several matings and crossings were needed to generate female mice of which both alleles of exon 1 is flanking by two loxP sites. We are now at the final stage of the mating and crossing. We hope very soon we will have our mouse model to study the question whether the EGF receptor plays a functional role in the etiology and progression of mammary carcinoma. The answer to this question would indicate the feasibility of using the EGF receptor as a target in breast cancer therapy.
Electrocatalytically Active Graphene–Porphyrin MOF Composite for Oxygen Reduction Reaction (2012)

Pyridine-functionalized graphene (reduced graphene oxide) can be used as a building block in the assembly of metal organic framework (MOF). By reacting the pyridine-functionalized graphene with iron-porphyrin, a graphene-metalloporphyrin MOF with enhanced catalytic activity for oxygen reduction reactions (ORR) is synthesized. The structure and electrochemical property of the hybrid MOF are investigated as a function of the weight percentage of the functionalized graphene added to the iron-porphyrin framework. The results show that the addition of pyridine-functionalized graphene changes the crystallization process of iron-porphyrin in the MOF, increases its porosity, and enhances the electrochemical charge transfer rate of iron-porphyrin. The graphene-metalloporphyrin hybrid shows facile 4-electron ORR and can be used as a promising Pt-free cathode in alkaline Direct Methanol Fuel Cell.
A same-frequency cellular repeater using adaptive feedback cancellation (2012)

A same-frequency cellular repeater is proposed that uses adaptive signal processing to cancel the feedback path, thereby allowing high gain while maintaining stability. This technique has application wherever it is desired to boost signal strength in outlying areas of cell coverage, particularly inside homes and buildings. It is intended to provide useful gain without needing special donor/transmit antennas requiring directional gain, separation beyond a meter or so, or roof installation. A simulation of a 900-MHz repeater with 10-MHz bandwidth is presented that demonstrates the feasibility and determines the effect of parameter values on convergence and cancellation performance.
Performance of GMSK with two-bit differential detection in a land mobile radio channel (1994)

The performance of two-bit differential detection of Gaussian minimum-shift keying (GMSK) in a cellular mobile communication channel is theoretically analyzed. The channel is modelled to reflect those encountered in a practical system; i.e., a frequency-selective fast Rayleigh-fading channel corrupted by cochannel interference and additive white Gaussian noise. A two-ray model for the channel is used and a single cochannel interferer is considered in the analysis. The Doppler effect is included as well. A closed-form expression for the probability of error is obtained. Numerical computation is used to obtain GMSK bit-error-rate performance for various combinations of channel parameters. The results are compared with those for limiter-discriminator detection with the same channel parameters. The performance of limiter-discriminator detection is found to be superior to that of two-bit differential detection. As two-bit differential detection is generally simpler to implement, the choice of detection method involves a performance versus complexity trade-off. The results presented can be used to make this trade-off.