gebhart/patrepeval huggingface dataset:
Experimental autoimmune myasthenia: A model of myasthenia gravis in rats and guinea pigs. (1975)

Immunization of animals with acetylcholine receptor (AChR) protein from the electric organs of Electrophorus electricus and Torpedo californica induces an autoimmune response to the AChR of mammalian skeletal muscle. Rats and guinea pigs develop experimental autoimmune myasthenia gravis (EAMG) after a single inoculation with small quantities of AChR and adjuvant. The indicence and severity of disease appears to depend on the dose of AChR and stability of the emulsion. EAMG is strikingly similar to myasthenia gravis (MG) of man in its clinical picture and its electrophysiological abnormalities. The presence of antibodies to syngeneic rat muscle AChR in the serum of rats with EAMG documents the existence of autoimmunity in the experimental disease. A common immunopathogenesis is suggested for both EAMG and mg.
Lessons Learned during Dengue Outbreaks in the United States, 2001–2011 (2012)

Since 2001, three autochthonous dengue fever outbreaks have occurred in the United States: in Hawaii (2001); Brownsville, Texas (2005); and southern Florida (2009-2011). We sought to characterize and describe the response to these outbreaks from the perspectives of public health and vector control officials. By conducting a medical literature review through PubMed and news media searches through Google, we identified persons involved in managing each outbreak; 26 persons then participated in qualitative, semistructured interviews. After analyzing the 3 outbreaks, we found the following prominent themes in the response efforts: timely detection of illness; communication of up-to-date, correct information; and development of a rapid response that engages the community. We therefore recommend that public health authorities involve the clinical and laboratory community promptly, provide accurate information, and engage the local community in vector control and case identification and reporting.
Population of sensory neurons essential for asthmatic hyperreactivity of inflamed airways (2014)

Significance Asthma is an inflammatory airway disease characterized by acute attacks in which airway constriction impedes breathing. The variable success of anti-inflammatory treatments in managing asthma attacks suggests that additional mechanisms contribute to this symptom. Here, we used a mouse model of acute asthma to show that a subset of sensory neurons mediates the hyperreactive airway responses. These findings define a cellular substrate outside the immune system that may serve as an important target in the management of asthmatic airway hyperreactivity.
Diagnosis and Treatment of Cystic Fibrosis (2000)

This review discusses some diagnostic aspects of cystic fibrosis (CF) including direct mutational analysis. Treatment of major disease manifestations is discussed in more detail with an emphasis on lung disease, in particular chronic infection with Pseudomonas aeruginosa which is responsible for the majority of excess morbidity and mortality. Centralised care and aggressive antimicrobial treatment have led to increased life expectancy and this may be even further increased by the demonstration that chronic P. aeruginosa infection may be prevented, or at least postponed for many years in a majority of patients. Adjunct treatment such as the use of local and systemic anti-inflammatory agents and inhalation of human recombinant DNase are also briefly touched upon. It is emphasised that important questions concerning the link(s) between the mutated gene and lung disease are still missing but that current research raises hope of a more causal treatment in the near future.
Subsolidus Compatibilities in the Y <sub>2</sub> O <sub>3</sub> ‐BaO‐CuO System via Diamagnetic Susceptibility (1987)

Subsolidus compatibilities in the YO 1.5 ‐BaO‐CuO system involving the superconducting 1:2:3 compound have been determined via optical microscopy, X‐ray diffraction, and diamagnetic susceptibility measurements. The susceptibility is particularly sensitive to the presence or absence of the superconducting phase.
Muscle myostatin signalling is enhanced in experimental cancer cachexia (2008)

These observations suggest that myostatin pathway should be regarded as a potential therapeutic target in cancer cachexia.
Visualization and Clustering of Business Process Collections Based on Process Metric Values (2008)

Motivated by ideas of software measurement, the area of process measurement has attracted attention in recent time. Numerous process metrics have been proposed to measure (often structural) properties of business processes.In this paper, we propose heatmaps, a visualization technique for high-dimensional data originally used in genetics, for visualizing the process metric values of business process collections. So, new insights into the distribution of the metric values among the processes could be gained. Additionally, we use clustering for analyzing (1) the correlations between different process metrics and (2) finding (structurally) similar processes among business process collections. Our approach has been successfully applied to the SAP Reference Model processes.
Semantic Web Fundamentals (2005)

The World Wide Web (Berners-Lee, Cailliau, & Groff, 1992; Berners-Lee, 1999) has changed the way people communicate with each other and the way business is conducted. It lies at the heart of a revolution that is currently transforming the developed world toward a knowledge economy (Neef, 1997), and more broadly speaking, to a knowledge society.
Power converter based method for suppressing power capacitor harmonic current (2004)

The damage to power capacitors caused by harmonic pollution was very serious in recent years due to the wide spread of power electronic related, nonlinear loads. The violent failure of power capacitors may result in power interruption and even accidents in industry. In this paper, a novel converter based protection method is proposed for protecting the power capacitor from harmonic damage. A power converter, serially connected to the power capacitor, is used to generate the harmonic components of utility voltage in the proposed method. Hence, the harmonic voltage across the power capacitor is cancelled. It means that the voltage dropped in the power capacitor will be maintained as sinusoidal, despite the waveform distortion of the utility voltage; the current flowing through the power capacitor is then also sinusoidal. Therefore, the power capacitor will not be damaged by the harmonic. A prototype is developed and tested to verify the performance of the proposed method. The test results show that the proposed method has the expected performance.
Human-Computer Interaction in the Control of Dynamic Systems (1981)

Modes of human-computer interaction in the control of dynamic systems are discussed, and the problem of allocating tasks between human and computer considered. Models of human performance in a variety of tasks associated with the control of dynamic systems are reviewed. These models are evaluated in the context of a design example involving human-computer interaction in aircraft operations. Other examples include power plants, chemical plants, and ships.
Health effects of omega-3,6,9 fatty acids: Perilla frutescens is a good example of plant oils (2011)

Perilla frutescens seeds are a good source of polyunsaturated fatty acids (PUFAs). The seeds of perilla are small end globular weight about 4 g/1000, contained approximately 35-45% oil. However the leaves are a very poor source of oil, since they contain only 0.2%. In addition, only the seed oil contains the omega 3 fatty acid alpha-linolenic acid (ALA). In comparing to other plant oils, perilla seed oil consistently contains the one of the highest proportion of omega-3 (ALA) fatty acids, at 54-64%. The omega-6 (linoleic acid) component is usually around 14% and omega-9 (Oleic acid) is also present in perilla oil. These polyunsaturated fatty acids are most beneficial to human health and in prevention of different diseases like cardiovascular disorders, cancer, inflammatory, rheumatoid arthritis etc.
MCM systems with waveform shaping in multi-user environments: effects of fading, interference and timing errors (2002)

A unified procedure to characterize the effect of interchannel and intersymbol interference, Doppler and fading in multicarrier modulation (MCM) systems, is presented. The effect of different waveform shapes is considered in order to check the possibility of utilizing MCM as a multiple access technique. The degradation of system performance due to time and frequency offsets typical of multi-user environments is evaluated. In order to compare in a concise way different schemes, graphs showing time-frequency signatures, are introduced. The effect of the number of subcarriers and sampling frequency offsets in FFT-based implementation is also taken into account.
Altered expression and endocytic function of CD205 in human dendritic cells, and detection of a CD205–DCL‐1 fusion protein upon dendritic cell maturation (2006)

CD205 (DEC-205) is a member of the macrophage mannose receptor family of C-type lectins. These molecules are known to mediate a wide variety of biological functions including the capture and internalization of ligands for subsequent processing and presentation by dendritic cells. Although its ligands await identification, the endocytic properties of CD205 make it an ideal target for those wishing to design vaccines and targeted immunotherapies. We present a detailed analysis of CD205 expression, distribution and endocytosis in human monocyte-derived dendritic cells undergoing lipopolysaccharide-induced maturation. Unlike other members of the macrophage mannose receptor family, CD205 was up-regulated upon dendritic cell maturation. This increase was a result of de novo synthesis as well as a redistribution of molecules from endocytic compartments to the cell surface. Furthermore, the endocytic capacity of CD205 was abrogated and small amounts of the recently identified CD205-DCL-1 fusion protein were detected in mature DC. Our results suggest that CD205 has two distinct functions -- one as an endocytic receptor on immature dendritic cells and a second as a non-endocytic molecule on mature dendritic cells -- and further highlight its potential as an immuno-modulatory target for vaccine and immunotherapy development.
Experimental Realization of Decoy State Polarization Encoding Measurement-device-independent Quantum Key Distribution (2013)

Quantum key distribution (QKD) allows two remote parties to generate secret keys for cryptographic purposes. Its security has been proven with some assumptions. However, practical realizations may not comply with all the assumptions, leading to various attacks. Founded on the observation that almost all attacks are on the detection part, measurement-device-independent QKD (MDI-QKD) was proposed to remove all such attacks. This thesis presents an implementation of the protocol. In our implementation, key bit information was encoded in the polarization states of weak coherent pulses at 1542 nm wavelength in optical fibers, and decoy state techniques were employed. We ensured stable polarization preparation and alignment and developed a QKD system over 10 km of standard Telecom fibers at 500 KHz repetition rate. Our work demonstrates the practicality of MDI-QKD protocol of removing all attacks, existing and yet to be discovered, on the detection part of a QKD system.
Loaded Custom‐Made Zirconia and Titanium Implants Show Similar Osseointegration: An Animal Experiment (2004)

Within the limits of this animal experiment, it can be concluded that the custom-made zirconia implants osseointegrated to the same extent as custom-made titanium control implants and show the same peri-implant soft tissue dimensions.
Reactions of a Cyclic Rhodium Carbenoid with Aromatic Compounds and Vinyl Ethers (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReactions of a Cyclic Rhodium Carbenoid with Aromatic Compounds and Vinyl EthersMichael C. Pirrung, Jiancun Zhang, Karen Lackey, Daniel D. Sternbach, and Frank BrownCite this: J. Org. Chem. 1995, 60, 7, 2112–2124Publication Date (Print):April 1, 1995Publication History Published online1 May 2002Published inissue 1 April 1995https://pubs.acs.org/doi/10.1021/jo00112a036https://doi.org/10.1021/jo00112a036research-articleACS PublicationsRequest reuse permissionsArticle Views1356Altmetric-Citations84LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information Get e-Alerts
Control of emission spectra in quantum dot microdisk/microring lasers (2014)

Focused ion beam is applied to quantum dot based microresonators to form pits or groove on their surface. The emission spectra of the resonators based lasers are significantly thinned out after the ion beam milling, and one or two modes become dominant instead of a group of modes having comparable intensities. The linewidth of the lasing mode is kept unchanged, whereas the lasing threshold demonstrates an insignificant growth.
Controlling the Resonance of a Photonic Crystal Microcavity by a Near-Field Probe (2005)

We demonstrate theoretically that the resonance frequencies of high-Q microcavities in two-dimensional photonic crystal membranes can be tuned over a wide range by introducing a subwavelength dielectric tip into the cavity mode. Three-dimensional finite-difference time-domain simulations show that by varying the lateral and vertical positions of the tip, it is possible to tune the resonator frequency without lowering the quality factor. Excellent agreement with a perturbative theory is obtained, showing that the tuning range is limited by the ratio of the cavity mode volume to the effective polarizability of the nanoperturber.
The 'voetstoots clause' in property sale agreements : property (2012)

This is no longer an automatic defence against defects that come to light after the agreement has been signed.
<i> <scp>C</scp> ognatishimia </i> (2019)

Abstract Cog.na.ti.shi'mi.a. L. masc. adj. cognatus relative, related, kindred; N.L. fem. n. Shimia a bacteria generic name; N.L. fem. n. Cognatishimia related to Shimia . Gram‐negative‐staining, aerobic, and catalase‐ and oxidase‐positive rods. Optimal growth occurs at 30°C, 2% (w/v) NaCl, and pH 7.0–8.0. Capable of degrading a variety of carbon sources including carbohydrates, alcohols, carboxylic acids, and amino acids. The principal fatty acid is C 18 :1 ω7 c . The major respiratory quinone is Q‐10. The type species was isolated from the seawater of the South Sea of Korea. Member of the family Rhodobacteraceae . The type species is Cognatishimia maritima . DNA G + C content (mol%) : 57 (LC). Type species : Cognatishimia maritima (Park, Lee, Lee, Oh and Yoon 2012) Wirth and Whitman 2018, 2403 VP (Park, Lee, Lee, Oh and Yoon 2012, 11). Taxonomic and Nomenclature Notes According to the List of Prokaryotic names with Standing in Nomenclature (LPSN), the taxonomic status of the genus Cognatishimia is: correct name (last update, February 2025) * . LPSN classification: Bacteria / Pseudomonadati / Pseudomonadota / Alphaproteobacteria / Rhodobacterales / Roseobacteraceae / Cognatishimia The genus Cognatishimia can also be recovered in the Genome Taxonomy Database (GTDB) as g__Cognatishimia (version v220) ** . GTDB classification: d__Bacteria / p__Pseudomonadota / c__Alphaproteobacteria / o__Rhodobacterales / f__Rhodobacteraceae / g__Cognatishimia * Meier‐Kolthoff et al. ( 2022 ). Nucleic Acids Res , 50 , D801 – D807 ; DOI: 10.1093/nar/gkab902 ** Parks et al. ( 2022 ). Nucleic Acids Res , 50 , D785 – D794 ; DOI: 10.1093/nar/gkab776
Induction of a protective response in swine vaccinated with DNA encoding foot-and-mouth disease virus empty capsid proteins and the 3D RNA polymerase (2001)

This work focuses on the development of a potential recombinant DNA vaccine against foot-and-mouth disease virus (FMDV). Such a vaccine would have significant advantages over the conventional inactivated virus vaccine, in particular having none of the risks associated with the high security requirements for working with live virus. The principal aim of this strategy was to stimulate an antibody response to native, neutralizing epitopes of empty FMDV capsids generated in vivo. Thus, a plasmid (pcDNA3.1/P1-2A3C3D) was constructed containing FMDV cDNA sequences encoding the viral structural protein precursor P1-2A and the non-structural proteins 3C and 3D. The 3C protein was included to ensure cleavage of the P1-2A precursor to VP0, VP1 and VP3, the components of self-assembling empty capsids. The non-structural protein 3D was also included in the construct in order to provide additional stimulation of CD4(+) T cells. When swine were immunized with this plasmid, antibodies to FMDV and the 3D polymerase were synthesized. Furthermore, neutralizing antibodies were detected and, after three sequential vaccinations with DNA, some of the animals were protected against challenge with live virus. Additional experiments suggested that the antibody response to FMDV proteins was improved by the co-administration of a plasmid encoding porcine granulocyte-macrophage colony-stimulating factor. Although still not as effective as the conventional virus vaccine, the results encourage further work towards the development of a DNA vaccine against FMDV.
사회변화 대응형 공공시설관리(P-FM)서비스 수립을 위한 국내외 시설관리기준 비교분석 연구 (2017)

Public facilities in korea are managed by a limited budget and follow-up management, and about 35 % of them are over 20 years after construction. Despite growing demand for repair, it is more difficult to acquire a budget due to low growth rates and rising debt ratios. As the service level of public FM increases gradually, there is no proper response to deterioration due to a lack of understanding of social change. This is a time to plan public facilities management strategies in the life cycle of public facilities. In this study, the basic research was conducted to establish efficient FM service system for the public facilities reflecting needs of public and society, and to compare and analyze the facility management standards of Korea, Japan, Europe, the United States, and Australia. Ultimately, it should have integrated facility management for proper operation and management in the building's life cycle.
Freqüência de diabetes mellitus e hiperglicemia em mulheres chagásicas e não-chagásicas (1999)

Medical records of > or = 40 years old female seen at University Hospital from June/93 to July/95 were submitted to a cross-sectional study. According to Chagas' disease tests, patients were divided into chagasic (n = 362) and controls (n = 285). Diabetes mellitus was defined on the basis of two fasting blood glucose levels > or = 140 mg/dl and hyperglycemia as fasting blood glucose > 110 mg/dl. Chagasic patients were divided into groups with the cardiac form of the disease (n = 179), with megas (n = 58), and asymptomatic (n = 125). Groups were compared by the chi 2 test, analysis of variance, Student's "t" test, and Kruskal-Wallis and Mann-Whitney tests. A significant difference was assumed when p < 0.05. Chagasic and control groups were matched for age, white color and body mass index. Diabetes mellitus was more prevalent in patients with the cardiac form of Chagas' disease than in controls, or patients with the megas or the asymptomatic form (15.1%, 7.4%, 7.4%, and 5.6%, respectively); the same was observed for hyperglycemia (37.4%, 26.7%, 25.9%, 27.2%), in agreement with the hypothesis that the reduced parasympathetic activity caused by Trypanosoma cruzi leads to relative sympathetic hyperactivity.
Effect of Composition on Resist Dry-Etching Susceptibility (1982)

Plasma and reactive-ion etching and ion-milling etch rates for a group of vinyl polymer resists and photoresists have been determined and found to vary by over a factor of 20 as the vinyl side-group substituents were altered synthetically or the photoresist varied. Lower etch rates or better etch compatibilities are observed for vinyl polymer resists containing multiply-bonded and unsaturated side-groups, as well as for lithographically negative behaving systems. Generally, better etch compatibilities were observed for the photoresist systems although a couple of the vinyl systems did perform as well. The etch selectivities and trends, measured versus PMMA or Si02 , are reasonably constant for the three etch techniques, except for the negative photoresists. Polymer resists (1) serve as masking layers in the patterning of the dielectric and conducting layers encountered in integrated circuit (IC) fabrication. When IC device geometries were greater than 5 micrometers, the critical dimensions of these IC
The AM/sup 3/ associative processor (1995)

As an associative 32-bit processor based on a modified Harvard architecture, the Associative Microprogrammable Multipurpose Monoprocessor (AM/sup 3/) uses a standard address-bus system to handle von Neumann data and instructions. A separate addressless associative bus system links it to associative memory components. Its microprogrammability enables the AM/sup 3/ to adapt to a variety of associative memory circuits. After discussing the AM/sup 3/ architecture and programming environment, we present two application paradigms.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
A modular method for the extraction of DNA and RNA, and the separation of DNA pools from diverse environmental sample types (2015)

A method for the extraction of nucleic acids from a wide range of environmental samples was developed. This method consists of several modules, which can be individually modified to maximize yields in extractions of DNA and RNA or separations of DNA pools. Modules were designed based on elaborate tests, in which permutations of all nucleic acid extraction steps were compared. The final modular protocol is suitable for extractions from igneous rock, air, water, and sediments. Sediments range from high-biomass, organic rich coastal samples to samples from the most oligotrophic region of the world’s oceans and the deepest borehole ever studied by scientific ocean drilling. Extraction yields of DNA and RNA are higher than with widely used commercial kits, indicating an advantage to optimizing extraction procedures to match specific sample characteristics. The ability to separate soluble extracellular DNA pools without cell lysis from intracellular and particle-complexed DNA pools may enable new insights into the cycling and preservation of DNA in environmental samples in the future. A general protocol is outlined, along with recommendations for optimizing this general protocol for specific sample types and research goals.