gebhart/patrepeval huggingface dataset:
Inhibition of Campylobacter jejuni colonization in chicks by defined competitive exclusion bacteria (1994)

Campylobacter enteritis in humans has been linked to consumption of chicken. Reducing Campylobacter jejuni colonization in chickens can potentially reduce Campylobacter infections in humans. In this study, the reduction of C. jejuni colonization in chicks by oral administration of defined competitive exclusion (CE) cultures, 2.5% dietary carbohydrates, or CE cultures and carbohydrates was examined. Prevention, elimination, or direct challenge of Campylobacter infection was simulated by administering treatments before, after, or at the same time as that of the Campylobacter inoculation. Additionally, the effect of maintaining high levels of protective bacteria was evaluated by administering CE cultures on days 1 and 4 (booster treatment). All treatments reduced C. jejuni colonization. Protection by aerobically grown CE cultures was not statistically different from that by anaerobically grown CE cultures. A combination of Citrobacter diversus 22, Klebsiella pneumoniae 23, and Escherichia coli 25 (CE 3) was the most effective CE treatment. Maintaining high numbers of CE isolates by administering CE boosters did not increase protection. The greatest reduction of Campylobacter colonization was observed in schemes to prevent or eliminate C. jejuni infection. C. jejuni was not detected in the ceca of birds receiving the prevention treatment, CE 3 with mannose, representing a 62% reduction in the colonization rate. The protection factor (PF), a value combining the colonization rate and the level of infection, for CE 3 with mannose was high (> 13.2). Fructo-oligosaccharides alone strongly prevented Campylobacter colonization. Only 8% of the chicks in this group were colonized, with a PF of > 14.3.(ABSTRACT TRUNCATED AT 250 WORDS)
Painful Lateral Knee Condyle Bone Marrow Edema after Treatment with Lateral Wedged Insole (2010)

A 50-yr-old man arrived at our department for a rehabilitation prescription after a right knee medial collateral ligament sprain. Magnetic resonance imaging showed medial collateral ligament partial rupture and medial femoral condyle increased signal intensity indicating bone edema. After treatment, the patient still complained of weight-bearing knee medial compartment pain. A lateral wedged insole was prescribed to decrease medial compartment compression forces. Initial response to insole use was good, but soon after, the patient complained of severe worsening knee pain. On examination, the lateral joint line and condyle palpation were tender. Insole use discontinuation was recommended, and another magnetic resonance imaging scan was performed. It showed an high T2-weighted signal intensity, representing bone marrow edema comprising a volume of 5 x 5 x 4.5 cm of lateral femoral condyle. Discontinuation of orthosis use relieved the pain, and the edema disappeared. To our knowledge, lateral femoral condyle painful bone marrow edema after lateral wedged insole use has not been previously described. The findings of this case report indicate that lateral wedged insole prescription should be carefully evaluated.
Volunteer computing (2001)

The explosive growth of interest in platform-independent programming languages for the World-Wide-Web, such as Sun Microsystems&apos; Java, is opening exciting new possibilites in parallel computing. This thesis will present and investigate the idea of volunteer computing, which will allow people to volunteer their computers&apos; processing power towards solving a large parallel problem by simply visiting a web page. Because it requires no prior human contact and very little technical knowledge from the client user, volunteer computing makes it possible to very easily build very large networks of computers working together in parallel. This makes supercomputing more readily accessible and &quot;closer to the masses&quot;, and at the same time makes it possible to achieve new heights in performance through the formation of parallel computing networks involving many thousands, or even millions, of computers distributed around the world. This paper proposes thesis research which aims to expose an...
Analysis of human computer interaction behavior for assessment of affect, cognitive load, and credibility (2015)

This dissertation presents three studies consisting of seven experiments that investigate the relationship between human-computer interaction (HCI) behavior and changes in cognitive states by using keystroke dynamics (KD) and mouse dynamics (MD) as physiological indicators of cognitive change. The first two chapters discuss the importance of being able to detect changes in affect, cognitive load, and deception and provide a theoretical base for this research, pulling heavily from cognitive science, psychology and communication literature. We also discuss the current state of the art in keystroke and mouse dynamics and what makes the techniques presented here different. Chapters three and four present five experiments that explore the influence of affect and cognitive load on KD and MD. The results of these experiments suggest that many features of typing and mouse movement behavior including transition time, rollovers, duration, number of direction changes, and distance traveled are influenced by changes in affect and cognitive load. In chapter five we operationalize these findings in a credibility assessment context and describe two experiments in which participants behave deceptively in computer mediated interactions. In both experiments, we find significant differences in typing behavior, in line with the findings of the first two studies. Chapter six summarizes the results and provides a way forward for future research in human computer interaction. The work presented in this dissertation describes a novel approach to inferring cognitive changes using low cost, non-invasive, and transparent monitoring of HCI behavior with important implications for both research and practice.
High-Power DBR-Tapered Laser at 980 nm for Single-Path Second Harmonic Generation (2009)

We present experimental results about edge-emitting distributed-Bragg-reflector-tapered diode lasers emitting at 980 nm. The investigated lasers show an output power of up to 12 W with a conversion efficiency of about 45%. The lasers also exhibit a small vertical divergence <15deg full-width at half maximum (FWHM), a nearly diffraction-limited beam quality, and a narrow spectral linewidth with FWHM smaller than 12 pm. These properties allow efficient single-pass second harmonic generation with power levels of more than 1 W at 488 nm.
A Design and Implementation of Application S/W Based on a Quality Evaluation of S/W (2002)

In general, most of koreans usually have used Hangul and MS-word as a Word Processor. We studied about the functional efficiency by comparing and analyzing Text Mode Equation Mode, Table Mode, Frame Editor & OLE Mode, Chart Mode and the other Modes to evaluate the common utility used Hangul 97 and MS-word 97 as a Word Processor. As a result, File size, Drag & Drop. Compression and storage etc. have been recognized characters remarkably in each case. We studied about Hangul 97, MS-word 97 as a user for evaluation criteria items. As a matter of fact, we used Tool Book and Director. So, we designed, developed and materialized S/W “garbage generation, separation, and collection” and then we also compared and examined those Text Mode. Sound Mode. Summation Algorithm Mode and Moving image Mode. In consequence, a user's point of view, characters of Tool Book and Director are showed remarkably through the findings of the questionnaire.
Defining and Overcoming the Contact Resistance Challenge in Scaled Carbon Nanotube Transistors (2014)

Carbon nanotubes (CNTs) continue to show strong promise as the channel material for an aggressively scaled, high-performance transistor technology. However, there has been concern regarding the contact resistance (Rc) in CNT field-effect transistors (CNTFETs) limiting the ultimate performance, especially at scaled contact lengths. In this work, the contact resistance in CNTFETs is defined in the context of a high-performance scaled transistor, including how the demonstrated Rc relates to technology targets. The impact of different source/drain contact metals (Pd, Pt, Au, Rh, Ni, and Ti) on the scaling of Rc versus contact length is presented. It is discovered that the most optimal contact metal at long contact lengths (Pd) is not necessarily the best for scaled devices, where a newly explored scaled metal contact, Rh, yields the best scaling trend. When extrapolated for a sub-10 nm transistor technology, these results show that the Rc in scaled CNTFETs is within a factor of 2 of the technology target with much potential for improvement through enhanced understanding and engineering of transport at the metal-CNT interface.
Spatial resolution correction for wall-bounded turbulence measurements (2011)

A correction for streamwise Reynolds stress data acquired with insufficient spatial resolution is proposed for wall-bounded flows. The method is based on the attached eddy hypothesis to account for spatial filtering effects at all wall-normal positions. This analysis reveals that outside the near-wall region the spatial filtering effect scales inversely with the distance from the wall, in contrast to the commonly assumed scaling with the viscous length scale. The new formulation is shown to work very well for data taken over a wide range of Reynolds numbers and wire lengths.
A Randomized Clinical Trial of a Single Dose of Intravitreal Triamcinolone Acetonide for Neovascular Age-Related Macular Degeneration (2003)

A single dose of intravitreal triamcinolone had no effect on the risk of loss of visual acuity during the first year of the study in eyes with age-related macular degeneration and classic choroidal neovascularization, despite a significant antiangiogenic effect found 3 months after treatment. This biological effect warrants further study.
Evaluating the Impact of Binning 2D Scalar Fields (2016)

The expressiveness principle for visualization design asserts that a visualization should encode all of the available data, and only the available data, implying that continuous data types should be visualized with a continuous encoding channel. And yet, in many domains binning continuous data is not only pervasive, but it is accepted as standard practice. Prior work provides no clear guidance for when encoding continuous data continuously is preferable to employing binning techniques or how this choice affects data interpretation and decision making. In this paper, we present a study aimed at better understanding the conditions in which the expressiveness principle can or should be violated for visualizing continuous data. We provided participants with visualizations employing either continuous or binned greyscale encodings of geospatial elevation data and compared participants' ability to complete a wide variety of tasks. For various tasks, the results indicate significant differences in decision making, confidence in responses, and task completion time between continuous and binned encodings of the data. In general, participants with continuous encodings were faster to complete many of the tasks, but never outperformed those with binned encodings, while performance accuracy with binned encodings was superior to continuous encodings in some tasks. These findings suggest that strict adherence to the expressiveness principle is not always advisable. We discuss both the implications and limitations of our results and outline various avenues for potential work needed to further improve guidelines for using continuous versus binned encodings for continuous data types.
Geysers advanced direct contact condenser research (1997)

The first geothermal application of the Advanced Direct Contact Condenser (ADCC) technology developed by the National Renewable Energy Laboratory (NREL) is now operational and is being tested at The Geysers Power Plant Unit 11. This major research effort is being supported through the combined efforts of NREL, The Department of Energy (DOE), and Pacific Gas and Electric (PG&E). NREL and PG&E have entered into a Cooperative Research And Development Agreement (CRADA) for a project to improve the direct-contact condenser performance at The Geysers Power Plant. This project is the first geothermal adaptation of an advanced condenser design developed for the Ocean Thermal Energy Conversion (OTEC) systems. PG&E expects this technology to improve power plant performance and to help extend the life of the steam field by using steam more efficiently. In accordance with the CRADA, no money is transferred between the contracting parties. In this case the Department of Energy is funding NREL for their efforts in this project and PG&E is contributing funds in kind. Successful application of this technology at The Geysers will provide a basis for NREL to continue to develop this technology for other geothermal and fossil power plant systems.
Corticosteroids for the Prevention of Atrial Fibrillation After Cardiac Surgery (2007)

clinicaltrials.gov Identifier: NCT00442494.
The UBIAD1 Prenyltransferase Links Menaquione-4 Synthesis to Cholesterol Metabolic Enzymes (2012)

Schnyder corneal dystrophy (SCD) is an autosomal dominant disease characterized by germline variants in UBIAD1 introducing missense alterations leading to deposition of cholesterol in the cornea, progressive opacification, and loss of visual acuity. UBIAD1 was recently shown to synthesize menaquinone-4 (MK-4, vitamin K(2) ), but causal mechanisms of SCD are unknown. We report a novel c.864G>A UBIAD1 mutation altering glycine 177 to glutamic acid (p.G177E) in six SCD families, including four families from Finland who share a likely founder mutation. We observed reduced MK-4 synthesis by UBIAD1 altered by SCD mutations p.N102S, p.G177R/E, and p.D112N, and molecular models showed p.G177-mutant UBIAD1 disrupted transmembrane helices and active site residues. We show UBIAD1 interacts with HMGCR and SOAT1, enzymes catalyzing cholesterol synthesis and storage, respectively, using yeast two-hybrid screening and immunoprecipitation. Docking simulations indicate cholesterol binds to UBIAD1 in the substrate-binding cleft and substrate-binding overlaps with GGPP binding, an MK-4 substrate, suggesting potential competition between these metabolites. Impaired MK-4 synthesis is a biochemical defect identified in SCD suggesting UBIAD1 links vitamin K and cholesterol metabolism through physical contact between enzymes and metabolites. Our data suggest a role for endogenous MK-4 in maintaining cornea health and visual acuity.
Star Synthesis Using Macroinitiators <i>via</i> Electrochemically Mediated Atom Transfer Radical Polymerization (2013)

Electrochemically mediated atom transfer radical polymerization (eATRP) was investigated for synthesis of star polymers using macroinitiators (MIs), achieving high star yield with low Cu catalyst loading (∼100 ppm, w/w). The arm first method, using MIs, is one of the most robust procedures for star polymer synthesis. During the polymerization, MIs can react with cross-linkers (divinyl or multivinyl compounds) for initial chain extension followed by the cross-linking reaction. The MIs can be transformed to arms of the star, and the cross-linker can form the star core. In this study, poly(ethylene oxide) (PEO, Mn = 2000) based MIs (PEO MIs) were prepared, and the chain-end functionalities were confirmed by 1H NMR analysis. The ATRP functionalized PEO MIs were then used for the star synthesis by reacting with ethylene glycol diacrylate cross-linkers. Various experimental conditions were conducted for optimizing star formation, including MI concentration, MI to cross-linker molar ratio, and applied potential (Eapp).
Unconstrained global optimization using stochastic intergral equations (1995)

A stochastic method is described for solving unconstrained global optimization problems based on a special class of stochastic integral equations. An efficient algorithm is developed using a semi-implicit Euler method for the numerical solution of the stochastic integral equations. Interesting properties and a parallel implementation of the algorithm enable the treatment of problems with a large number of variables
Stable Positional Cloning of Long Continuous DNA in the Bacillus subtilis Genome Vector (2003)

Direct cloning of a long continuous genome segment in a Bacillus subtilis genome vector was demonstrated for the first time. Two small DNA fragments had to be installed in the vector prior to cloning. The DNA between these two fragments was cloned via homologous recombination. The efficiency of cloning was estimated using the 3,573-kb genome of a cyanobacterium, Synechocystis sp. PCC 6803. Recombinants were selected using the internal selection system of the Bacillus genome vector or with the antibiotic resistance marker in the cyanobacterial genome. Designated genomic segments as large as 77-kb were cloned by means of a single procedure. Cloning efficiency is affected by the molecular weight of the donor DNA and the size of the DNA to be cloned. The method is suitable for direct target cloning of large-sized DNA.
Graded-index Fresnel lenses for integrated optics (1982)

Fresnel waveguide lenses having a graded-index (GRIN) distribution for the segmented quadratic phase modulation are demonstrated. The GRIN Fresnel lenses exhibit excellent focusing characteristics and a very high efficiency, both limited only by diffraction. Graded-index Fresnel lenses (F/5, 1-mm aperture) were fabricated for the first time in amorphous As(2)S(3) film waveguides on a thermally oxidized silicon substrate by the electron-beam direct writing technique. The nearly diffraction-limited focusing characteristics and a high efficiency (48%) were experimentally obtained. The theoretical analysis and fabrication process are presented, and experimental results are discussed on the focusing characteristics of the fabricated GRIN Fresnel waveguide lens.
Full-screen high-resolution stereoscopic 3D display using LCD and EL panels (2006)

A display system that does not require viewers to wear special glasses to see 3D images is useful technology. Conventional 2-views lenticular and parallax-barrier display systems have disadvantages such that horizontal resolution is reduced by half because each eye only sees half the pixels. We describe a method to generate orthogonal polarized parallax images and a thin stereoscopic 3D display with a polarized parallax barrier. The advantage of the polarized parallax barrier is that the resolution of presented parallax images is much greater than that possible with conventional displays. This compact display has liquid crystal display(LCD) panels and/or Electoro Luminescence(EL) devices to present stereo views and to control polarization. It has twice the 3D image resolution, because the image plane can multiplex images with horizontal and vertical polarization to display stereo views.
ChemInform Abstract: Further Measurements of the Rotational Spectrum of COF2: Improved Molecular Constants for the Ground and ν2 States. (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Analysis of peptide residues interacting with MHC molecule or T cell receptor. Can a peptide bind in more than one way to the same MHC molecule? (1990)

It has generally been assumed implicitly that one can define amino acid residues of a T cell antigenic determinant peptide that interact with the MHC molecule, i.e., residues that form the "agretope." However, if the same peptide can be seen in different conformations or orientations in the same MHC molecule by different T cells, then we would predict that some residues would appear to interact with the TCR of one T cell clone but with the MHC molecule as the peptide is seen by another T cell clone. To test this hypothesis, we synthesized 36 analogue peptides of an immunogenic fragment (P133-146) of sperm whale myoglobin with three different substitutions for each of 12 amino-acid residues and analyzed the role of each residue for I-Ed-binding and for activation of two Th clones, 14.1 and 14.5, specific for the peptide. The two T cell clones showed slightly different fine specificity from each other in that the truncated peptide P136-144 could stimulate 14.5 but not 14.1. The binding activity of nonstimulatory analogues to the I-Ed molecule was measured by functional inhibition analyses using truncated wild-type peptides as stimulators and nonstimulatory analogues as inhibitors. Paradoxical results were obtained that could not be explained by the peptide binding in a single way to the same I-Ed molecule. Some residues appeared to reciprocally reverse their roles for binding to I-Ed vs binding to the TCR when assessed using T-cell clone 14.5 compared to clone 14.1. These results fit the prediction of the above hypothesis and indicate the possibility that the same peptide, P133-146, can bind in more than one way to the same Ia molecule. The T cell clones, 14.1 and 14.5, appear to recognize different P133-146-I-Ed complexes in which the peptide is bound differently. Moreover, a given residue may not have a unique function of always interacting with the MHC molecule or TCR, but may change from one role to the other as it is presented to different T cells.
Dupilumab as a Treatment for Allergic Contact Dermatitis (2018)

Chipalkatti, Naina BS; Lee, Nicole BA; Zancanaro, Pedro MD; Dumont, Nicole; Donovan, Courtney RN; Rosmarin, David MDAuthor Information
Thermal deactivation of strong-acid ion-exchange resins in water (1981)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThermal deactivation of strong-acid ion-exchange resins in waterLeonardus Petrus, Eize J. Stamhuis, and Geert E. H. JoostenCite this: Ind. Eng. Chem. Prod. Res. Dev. 1981, 20, 2, 366–371Publication Date (Print):June 1, 1981Publication History Published online1 May 2002Published inissue 1 June 1981https://pubs.acs.org/doi/10.1021/i300002a026https://doi.org/10.1021/i300002a026research-articleACS PublicationsRequest reuse permissionsArticle Views409Altmetric-Citations38LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts