gebhart/patrepeval huggingface dataset:
Uncertainty estimation of historical bathymetric data from Bayesian networks (2009)

We have developed a Bayesian network to aid estimation of uncertainty for gridded bathymetry data sets in the Digital Bathymetrie Data Base - Variable Resolution, maintained at the Naval Oceanographie Office. These estimates did not previously exist and are now needed so that these data can be stored in the Bathymetrie Attributed Grid files, which require both bathymetry and uncertainty. Monte Carlo simulations have been used in the literature to calculate how navigation error, sensor error, and bottom gradient propagates into bathymetrie uncertainty. This procedure, however, requires the use of original soundings data. Attempting this approach for all soundings used to make the data base is not pragmatic due to the vast quantity of data used. Bayesian networks can be a pragmatic alternative, however, as this approach propagates probability densities of the inputs to calculate probabilities of the end result, resulting in computations that are simpler and more rapid than direct simulations. Valid application of the technique relies on the assumption that measurement errors and bottom slope propagate into bathymetrie uncertainty independent of actual measurement location. We discuss how we used the published Monte Carlo techniques on representative sets of soundings data to train the network and implemented the network to estimate the propagation of navigation error and bottom slope to bathymetrie uncertainty in historic data. We also test the validity of applying this approach to estimate bathymetrie uncertainty through comparisons of these estimates from the Bayesian net and Monte Carlo techniques.
Noncovalent Side-Wall Functionalization of Single-Walled Carbon Nanotubes (2003)

A family of poly[(m-phenylenevinylene)-co-(p-phenylenevinylene)]s, functionalized in the synthetically accessible C-5 position of the meta-disubstituted phenylene rings have been designed and synthesized: they are essentially poly{(5-alkoxy-m-phenylenevinylene)-co-[(2,5-dioctyloxy-p-phenylene)vinylene]} (PAmPV) derivatives. A range of these PAmPV polymers have been prepared both (1) by the polymerization of O-substituted 5-hydroxyisophthaldehydes and (2) by chemical modifications carried out on polymers bearing reactive groups at the C-5 positions. PAmPV polymers solubilize SWNT bundles in organic solvents by wrapping themselves around the nanotube bundles. PAmPV derivatives which bear tethers or rings form pseudorotaxanes with rings and threads, respectively. The formation of the polypseudorotaxanes has been investigated in solution by NMR and UV/vis spectroscopies, as well as on silicon oxide wafers in the presence of SWNTs by AFM and surface potential microscopy. Wrapping of these functionalized PAmPV polymers around SWNTs results in the grafting of pseudorotaxanes along the walls of the nanotubes in a periodic fashion. The results hold out the prospect of being able to construct arrays of molecular switches and actuators.
A mechanical microscope: High-speed atomic force microscopy (2005)

An atomic force microscope capable of obtaining images in less than 20ms is presented. By utilizing a microresonator as a scan stage, and through the implementation of a passive mechanical feedback loop with a bandwidth of more than 2MHz, a 1000-fold increase in image acquisition rate relative to a conventional atomic force microscope is obtained. This has allowed images of soft crystalline and molten polymer surfaces to be collected in 14.3ms, with a tip velocity of 22.4cms−1 while maintaining nanometer resolution.
Bandwidth efficient combination for cooperative spectrum sensing in cognitive radio networks (2010)

In this paper, we investigate bandwidth efficient combination of spectrum sensing information in cooperative cognitive radio (CR) networks. We propose a general approach in which CR users are allowed to simultaneously send local sensing data to a combining node through a common control channel, based on which we discuss bandwidth efficient combination schemes under two different cases. In the proposed schemes, the bandwidth required for reporting is fixed regardless of the number of cooperative users. With proper preprocessing at individual users, the proposed schemes maintain reasonable performance with the superposition of sensing data at the combining node. Simulation results also demonstrate the effectiveness of the proposed approach.
Cross-Correlative Least-Squares Reverse Time Migration - Theory and Field Applications (2015)

We introduce a new practical least-squares reverse-time migration (LSRTM) scheme and derive a steepest descent method for optimal imaging by adapting reverse-time migration (RTM) and demigration (RTDM) as the migration and modelling operators to maximize the cross-correlation between simulated and acquired seismic data. Through real data experiments, we demonstrate that the proposed LSRTM provides high quality images with balanced amplitudes, improved focusing and enhanced resolution. The method is also capable of removing the free surface ghosts generated in towed streamer acquisition and filling holes in the imaged structures due to imperfect acquisition.Together with impedance perturbation technique, the proposed method is a useful tool for both seismic imaging and inversion.
G-rich Oligonucleotides Inhibit HIF-1α and HIF-2α and Block Tumor Growth (2009)

Hypoxia-inducible factor-1 (HIF-1) plays crucial roles in tumor promotion by upregulating its target genes, which are involved in energy metabolism, angiogenesis, cell survival, invasion, metastasis, and drug resistance. The HIF-1alpha subunit, which is regulated by O2-dependent hydroxylation, ubiquitination, and degradation, has been identified as an important molecular target for cancer therapy. We have rationally designed G-rich oligodeoxynucleotides (ODNs) as inhibitors of HIF-1alpha for human cancer therapy. The lead compounds, JG243 and JG244, which form an intramolecular parallel G-quartet structure, selectively target HIF-1alpha and decreased levels of both HIF-1alpha and HIF-2alpha (IC50 < 2 micromol/l) and also inhibited the expression of HIF-1-regulated proteins [vascular endothelial growth factor (VEGF), Bcl-2, and Bcl-XL], but did not disrupt the expression of p300, Stat3, or p53. JG-ODNs induced proteasomal degradation of HIF-1alpha and HIF-2alpha that was dependent on the hydroxylase activity of prolyl-4-hydroxylase-2. JG243 and JG244 dramatically suppressed the growth of prostate, breast, and pancreatic tumor xenografts. Western blots from tumor tissues showed that JG-ODNs significantly decreased HIF-1alpha and HIF-2alpha levels and blocked the expression of VEGF. The JG-ODNs are novel anticancer agents that suppress tumor growth by inhibiting HIF-1.
Pulsed Electron Gun (1987)

Magnetically-collimated electron gun generates electron pulses with peak instantaneous currents of approximately microA with pulse widths of approximately 0.35 ns.
Fast Wafer-Level Stress-and-Sense Methodology for Characterization of Ring-Oscillator Degradation in Advanced CMOS Technologies (2015)

Ring oscillators (ROs) are widely used to study the degradation of logic CMOS circuits. To successfully link the time dependence of the ROs frequency degradation to the degradation of discrete device, we introduce a novel, fast wafer-level stress-and-sense methodology. With this new methodology, we unambiguously show the close correlation between discrete device degradation and circuit aging at typical wafer-level stress times.
A vertically-loaded diamond microdisk resonator spin-photon interface (2021)

We propose and optimize a vertically-loaded diamond microdisk resonator (VLDMoRt) coupled to a nitrogen-vacancy (NV) center in diamond for efficient collection of zero-phonon-line emission into low numerical aperture (NA) free-space modes. The VLDMoRt achieves a Purcell enhancement of 172 with 39% of the emitted light collected within a NA of 0.6, leading to a total external spin-photon collection efficiency of 0.33. As the design is compatible with established nanofabrication techniques and couples to low-NA modes accessible by cryogenic free-space optical systems, it is a promising platform for efficient spin-photon interfaces based on diamond quantum emitters.
Secure Key Management for Flexible Digital Rights Management of Scalable Codestreams (2005)

The key management for multi-type, multi-level scalable access control of a fine granularity scalability codestream is addressed in this paper. We first present an efficient partially ordered set (poset) to represent scalable access control so that any access control schemes for a poset can be applied and a single secret key is needed to transfer to a user. We then present a secure key scheme modified from our previous scalable access key scheme for the resulting poset. The key scheme is based on the group Diffie-Hellman key agreement, and is secure
Functionalization of Fluoroalkyl Polyhedral Oligomeric Silsesquioxanes (F-POSS) (Post Print) (2012)

Abstract : Incompletely-condensed fluoroalkyl-functional Polyhedral Oligomeric SilSesquioxanes (F-POSS) have been synthesized via a scaleable three-step synthetic process with an overall yield of 52%. The primary byproduct of each step in the synthesis is the completely-condensed F-POSS starting material, which enables the recycling of the starting materials. The incompletely condensed structures were readily reacted with a variety of functional dichlorosilanes to introduce reactive or unreactive functionality and produce unsymmetrical F-POSS structures. Chemical structures were confirmed by elemental analysis, multinuclear NMR (1H, 13C, 19F, and 29Si), and FT-IR methods. Single crystal X-ray diffraction was used to elucidate the crystal structure of the precursor F-POSS disilanol. The functionalized F-POSS structures were found to possess variable solubility properties, generally superior to those of the closed-cage F-POSS starting material. Dynamic contact angle measurements of these compounds were examined using water and hexadecane as the wetting liquids. Copolymers of poly(methyl methacrylate) containing F-POSS were synthesized from methacrylate F-POSS macromers. These novel structures can be used as building blocks for the development of low surface energy materials.
Direct fermentation of 2-keto-l-gulonic acid in recombinantGluconobacter oxydans (1998)

We isolated Gluconobacter oxydans T-100 that had an activity to produce 2-KLGA from D-sorbitol; however, the yield of 2-KLGA was quite insufficient. Therefore, enzymes involved in the biosynthesis of L-sorbosone and 2-KLGA, L-sorbose dehydrogenase (SDH) and L-sorbosone dehydrogenase (SNDH), respectively, were purified from G. oxydans T-100. A genomic library of G. oxydans T-100 was screened to clone both genes for SDH and SNDH based on their amino acid sequences. SNDH and SDH were encoded in sequential open reading frames with 1497 and 1596 nucleotides, respectively, which were verified by the expression in Escherichia coli. The amino acid sequence of SDH and SNDH showed close similarity with E. coli choline dehydrogenase (CDH) and betaine-aldehyde dehydrogenase (BADH), respectively, which cooperatively play a key role for conferring osmotic tolerance. Because the yield of 2-KLGA by G. oxydans introduced with the genes for SDH and SNDH were insufficient, replacement of the promoter with that of Escherichia coli tufB1 in combination with chemical mutagenesis by N-methyl-N'-nitro-N-nitrosoguanidine resulted in improvement of the production level.
Using Analytics to Minimize Errors in the Connectivity Model of a Power Distribution Network (2015)

The connectivity model of a power distribution network can easily become outdated due to system changes. Maintaining and sustaining an accurate connectivity model is a key challenge for most distribution utilities today. This work presents novel analytics techniques that can infer the connectivity model from measurements already available from a distribution network. Our techniques utilize voltage data from customer smart meters and circuit metering points to identify and correct errors in the connectivity model. We report analysis results based on data collected from multiple feeders of a large electric distribution network in North America. Our analysis shows that customer voltage measurements exhibit hierarchical correlations, which can be exploited to cluster customers under the same distribution transformer or same phase with high accuracy. To the best of our knowledge, this is the first large scale measurement study of voltage data collected from smart meters and its use in inferring customer to transformer and phase connectivity information.
Non-mechanical zoom system (2004)

In order to optically vary the magnification of an imaging system, mechanical zoom lenses, such as those found on 35mm cameras, require multiple optical elements and use cams or gears to adjust the spacing between individual or groups of lenses. By incorporating active elements in the optical design, we can eliminate the need to change lens separations and create an imaging system with variable optical magnification that has no macroscopic moving parts.
Type 3 porous liquids based on non-ionic liquid phases – a broad and tailorable platform of selective, fluid gas sorbents (2020)

We describe a series of Type 3 porous liquids, denoted "T3PLs", based on a wide range of microporous solids including MOFs, zeolites and a porous organic polymer (PAF-1). These solids are dispersed in various non-ionic liquid phases (including silicone oils, triglyceride oils, and polyethylene glycols) which have a range of structures and properties, and that are in many cases sterically excluded from the pores of the solids. Several stable dispersions with high gas uptakes are obtained. We show how these dispersions can be tailored toward important gas separation processes (CO<sub>2</sub>/CH<sub>4</sub>, C<sub>2</sub>H<sub>4</sub>/C<sub>2</sub>H<sub>6</sub>) and applications that require biocompatibility.
Developments in Ethanol Production from Citrus Peel Waste (2008)

The Florida citrus juice industry produces about 3.5 to 5.0 million tons of wet peel waste annually. This material currently is dried and sold, often at a loss, as cattle feed to dispose of the waste residue. Profitability could be greatly improved if higher value products could be developed and produced from the peel waste. In this paper, the development of a new process to make ethanol along with improved recovery of D-limonene from citrus peel waste is discussed. The process consists of four parts: pretreatment to remove and recover D-limonene, simultaneous saccharification and fermentation (SSF) to produce ethanol, distillation to remove the ethanol and treatment of the residue for use as cattle feed or other co-products. Pilot plant studies have demonstrated that citrus processing waste can be fermented to produce ethanol (approximately 4% w/v) with D-limonene obtained as co-product. In order to design an efficient and cost-effective distillation column to strip off ethanol, the heat transfer coefficient and specific heat of fermented citrus processing waste was measured under forced convection using a heat exchanger. The technical difficulties of stripping off ethanol from fermented peels are also discussed. This new technology provides an alternative disposal of citrus peel waste in the citrus industry.
Novel sorbents for high-temperature regenerative H/sub 2/S removal. Final report (1985)

The overall objective of this program was to develop improved regenerable sorbents for the high-temperature desulfurization of coal-derived gas streams. The aim is to reduce the H/sub 2/S level, preferably in a single-stage, from 0.5 to 1.0 mol % down to 1 ppM. The specific objectives of this project were to synthesize, characterize and test two classes of sorbents. One consists of eutectic mixtures of metal oxides (e.g., ZnO-V/sub 2/O/sub 5/, CuMoO/sub 4/-MoO/sub 3/) in the form of a melt coating the pore surface of a high surface area solid support. The second class of sorbents includes unsupported mixed oxides, in the form of solid solutions or solid compounds, e.g., Zn-Fe/sub x/-O/sub y/, Cu-Fe/sub x/-O/sub y/, prepared as highly dispersed microcrystalline solids. The principal characteristics of both classes of sorbents are rapid kinetics of absorption, high absorption capacity and good regenerability. The rapid absorption kinetics are realized by eliminating or minimizing the resistance associated with solid state diffusion. With these properties, the sorbents would be suitable for coal gasification/molten carbonate fuel cell (MCFC) applications, but could also be applied to combined cycle power generation and the purification of synthesis gas. 22 refs., 31 figs., 31 tabs.
Immunological Abnormalities in Kawasaki Disease with Coronary Artery Lesions (1991)

A review of our previous immunological studies on Kawasaki disease (KD) was undertaken. The results showed that peripheral blood macrophages/monocytes, T-cells and B-cells become activated during acute KD in terms of numerical changes in immunocompetent cells, expression of activated antigens on the cell surfaces and cytokine production. Also, during acute KD with coronary artery lesions (CALs) the numbers of macrophages/monocytes are increased. In addition, both the increased levels of tumor necrosis factor-alpha and shed intercellular adhesion molecule-1 in serum are more evident in KD patients with CALs than in those without. Our results further suggest that the main characteristics of the pathogenesis of KD are increased numbers of peripheral blood macrophages/monocytes with the secretion of monokines by these activated cells, and the expression of adhesion molecules on immunocompetent cells. These immune responses develop more vigorously in KD patients with CALs.
Superantigens in Kawasaki Syndrome (1995)

Kawasaki syndrome (KS) is an acute multisystem vasculitis of infancy and early childhood associated with the development of myocarditis and coronary artery abnormalities. Despite the widely held belief that KS is caused by an infectious agent, there remains considerable controversy over its etiology. Recent immunologic and microbiologic studies suggest a potential role for staphylococcal and streptococcal toxins (superantigens) in the pathogenesis of KS. Confirmation of these findings could result in more effective diagnostic and therapeutic approaches to this common cause of acquired heart disease in children.
CD70 antibody therapy for the prevention and treatment of experimental Inflammatory Bowel Disease (IBD). (2008)

Background Inflammatory bowel disease is a chronic disorder of the gastrointestinal tract, characterized by an aberrant mucosal T cell‐mediated inflammation. The costimulatory molecule CD70 is constitutively expressed by a unique antigen presenting cell in the lamina propria and its interaction with T cells is critical for the gut mucosal T cell activation. Objective To test if blockade of CD70 reduces intestinal inflammation in an experimental model of colitis Methods Colitis was induced by adoptively transferring CD45RB hi CD4 + T cells into Rag 1 −/− mice, the mice were treated with control Ig or a blocking anti‐CD70 antibody twice weekly for 6‐8 weeks and the animals were monitored for disease development. Results Treatment with CD70 blocking antibody dramatically reduced the colitis‐associated weight loss, clinical symptoms and intestinal hisopathology. Importantly, anti‐CD70 antibody treatment initiated after onset of the disease was also able to partially reverse the features of colitis. The Th‐1 related cytokine IFNγ as well as key proinflammatory cytokines of the Th17 pathway, including IL‐23, IL‐17, IL‐6, and TNFα were significantly reduced after CD70 antibody treatment as compared to control group (p<0.001). Conclusion: This study shows that both Th1 and Th17 related cytokines play a dominant role in the pathogenesis of IBD and that CD70 blockade can effectively suppress these cytokines leading to reduction of inflammation. Source of Research support Crohn's and Colitis foundation of America (CCFA)
Surface roughness imaging using the acoustic emission induced by the dynamic radiation force of ultrasound (2006)

High frequency ultrasound imaging systems are traditionally used in industry to obtain high resolution images of solid surfaces, and in some cases, to evaluate surface roughness. In this study we show that imaging fine surface roughness in the order of few microns is achievable at audio range frequencies (kilohertz range) by using the vibroacoustography (VA) technique. This technique allows one to image surface roughness on the basis of the ultrasound radiation force stimulated acoustic emission in a standing ultrasound wave field. Images obtained here demonstrate that VA may be used as a powerful tool for nondestructive inspection and imaging of surface roughness.
Space-Variant Polarization-State Manipulation with Computer-Generated Subwavelength Gratings (2001)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text Ze'ev Bomzon, Gabriel Biener, Vladimir Kleiner, and Erez Hasman, "Space-Variant Polarization-State Manipulation with Computer-Generated Subwavelength Gratings," Optics & Photonics News 12(12), 33-33 (2001) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Optical fiber sensor using tailored porous sol-gel fiber core (2003)

Novel techniques for fabricating a porous sol-gel fiber, doping chemical reagent into the fiber, and constructing an optical fiber chemical sensor using the porous fiber as a transducer, have been invented. A moisture sensor employing a CoCl/sub 2/ doped porous sol-gel fiber as a transducer has been constructed as an example. The test result of the moisture sensor verified a conclusion from theoretical analysis. That is an optical fiber chemical sensor using an active fiber core as a transducer should have a much higher sensitivity than that of active coating based sensor.
ChemInform Abstract: SYNTHESIS OF PERFLUOROPOLYETHERS VIA HYDROCARBON POLYESTERS: A NEW GENERAL METHOD (1985)

Abstract Der verzweigte Polyester(I) sowie der lineare Polyester(VI) werden zunächst mit Fluor direkt in Perfluorpolyester übergeführt, die anschließend mit SF, in Perfluorpolyether umgewandelt werden.
Quantification of Prothrombin in Human Plasma Amplified by Autocatalytic Reaction (2012)

By site directed mutagenesis, we have produced recombinant mutants of human and mouse prethrombin-2 which are able to convert themselves autocatalytically into α-thrombin. We also have created a new method to amplify the signal of bioanalytical assays based on the autocatalytic activation of these mutated proenzymes. The activation of the mutants by active α-thrombin triggers an autocatalytic reaction which leads to more active thrombin resulting in the amplification of the readout signal. Addition of mutated mouse prethrombin-2 into the conventional assay for prothrombin level in human plasma, employing ecarin and the fluorogenic substrate, resulted in improvement of the detection limit by 2 orders of magnitude.