gebhart/patrepeval huggingface dataset:
Studies on the Zoarcidae (Teleostei: Perciformes) of the southern hemisphere. V. Two new species from the Weddell Sea, Antarctica (2023)

Two new species of deep-water eelpouts are described from specimens trawled in the Weddell Sea, Antarctica. One, Lycenchelys xanthoptera, is characterized by its yellow pectoral fins, absence of pelvic fins and palatine teeth, double lateral line, intermediate counts of the axial skeleton, and relatively few suborbital pores (5-6). The other, Pachycara goni, is characterized by its furcate gill rakers, mediolateral branch of the lateral line beginning on the tail, high precaudal vertebral count (27) and seven suborbital pores, all below the eye.
Oral Hydralazine in Chronic Heart Failure: Sustained Beneficial Hemodynamic Effects (1980)

Hemodynamic effects of oral hydralazine (200 to 400 mg/d) were evaluated in 11 patients with chronic heart failure after short-term (24 hours) and long-term (average, 8.3 months) therapy. In seven of 11 patients, hemodynamic changes were evaluated after withdrawal of hydralazine. During early study, cardiac index, stroke volume index, and stroke work index increased by an average of 56%, 59%, and 68%, respectively, and systemic vascular resistance decreased by 39%. During late study, cardiac index (+65%), stroke volume index (+88%), and stroke work index (+98%) remained higher and systemic vascular resistance (-41%) lower than control values. Withdrawal of hydralazine caused a decrease in cardiac index, stroke volume index, and stroke work index and an increase in systemic vascular resistance. Heart rate and arterial, pulmonary capillary wedge, and right atrial pressures did not change significantly. These findings suggest that oral hydralazine produces sustained beneficial hemodynamic effects in patients with chronic heart failure.
Design of a 28/38 GHz dual-band printed slot antenna for the future 5G mobile communication Networks (2015)

In this article, a dual-band printed slot antenna for the future fifth generation (5G) mobile networks are proposed. The antenna is compact with size of 0.8 λ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sub> × 0.75 λ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sub> at 28 GHz. Matching between a sector-disk shaped radiating patch and the 50-Ω microstrip line is manipulated through aproximity-feed technique. An elliptically shaped aperture is etched in the ground plane to enhance the antenna bandwidth. A shunt stub is used to get more enhancement of the impedance bandwidth of the antenna. To reduce the interference between the 5G system and other systems, π-shaped slot is etched off in the feed line to create a notched band of 30-34 GHz. The simulated results show that the designed antenna has a dual band function at 28/38 GHz that covers future 5G applications. The proposed antenna provides almost omni-directional patterns, relatively flat gain, and high radiation efficiency through the frequency band excluding the rejected band.
Active Reconfigurable Luneburg lens at 60GHz (2015)

International audience
Flexible optofluidic waveguide platform with multi-dimensional reconfigurability (2016)

Dynamic reconfiguration of photonic function is one of the hallmarks of optofluidics. A number of approaches have been taken to implement optical tunability in microfluidic devices. However, a device architecture that allows for simultaneous high-performance microfluidic fluid handling as well as dynamic optical tuning has not been demonstrated. Here, we introduce such a platform based on a combination of solid- and liquid-core polydimethylsiloxane (PDMS) waveguides that also provides fully functioning microvalve-based sample handling. A combination of these waveguides forms a liquid-core multimode interference waveguide that allows for multi-modal tuning of waveguide properties through core liquids and pressure/deformation. We also introduce a novel lifting-gate lightvalve that simultaneously acts as a fluidic microvalve and optical waveguide, enabling mechanically reconfigurable light and fluid paths and seamless incorporation of controlled particle analysis. These new functionalities are demonstrated by an optical switch with >45 dB extinction ratio and an actuatable particle trap for analysis of biological micro- and nanoparticles.
Taming chaos: a numerical experiment using low-order LTI filters (1995)

According to a recent paper by Jonckheere, Hammad, and Wu (1993), it is not possible to reduce the Kohnogorov-Sinai entropy by linear, stationary feedback, if the closed loop system is stable and minimum phase. This paper provides some extra insight into the understanding of this situation by bifurcation diagram (rather than entropy) analysis of three simple examples. In this numerical experiment, a chaotic signal is used as input to a linear filter that models the closed loop system. No forcing or tuning of the chaotic input is available. It appears that low-order LTI filters cannot tame chaos.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
METHOD TO PREVENT SULFUR ACCUMULATION INSIDE MEMBRANE ELECTRODE ASSEMBLY (2009)

HyS is conceptually the simplest of the thermochemical cycles and involves only sulfur chemistry. In the HyS Cycle hydrogen gas (H{sub 2}) is produced at the cathode of the electrochemical cell (or electrolyzer). Sulfur dioxide (SO{sub 2}) is oxidized at the anode to form sulfuric acid (H{sub 2}SO{sub 4}) and protons (H{sup +}) as illustrated below. A separate high temperature reaction decomposes the sulfuric acid to water and sulfur dioxide which are recycled to the electrolyzers, and oxygen which is separated out as a secondary product. The electrolyzer includes a membrane that will allow hydrogen ions to pass through but block the flow of hydrogen gas. The membrane is also intended to prevent other chemical species from migrating between electrodes and undergoing undesired reactions that could poison the cathode or reduce overall process efficiency. In conventional water electrolysis, water is oxidized at the anode to produce protons and oxygen. The standard cell potential for conventional water electrolysis is 1.23 volts at 25 C. However, commercial electrolyzers typically require higher voltages ranging from 1.8 V to 2.6 V [Kirk-Othmer, 1991]. The oxidation of sulfur dioxide instead of water in the HyS electrolyzer occurs at a much lower potential. For example, the standard cell potential for sulfur dioxide oxidation at 25 C in 50 wt % sulfuric acid is 0.29 V [Westinghouse, 1980]. Since power consumption by the electrolyzers is equal to voltage times current, and current is proportional to hydrogen production, a large reduction in voltage results in a large reduction in electrical power cost per unit of hydrogen generated.
A Stereospecific Ruthenium-Catalyzed Allylic Alkylation (2002)

Good regioselectivity and chirality transfer for aryl-substituted allyl units is achieved in allylic alkylations with a wide range of nucleophiles by using the highly active ruthenium catalyst 1. This method provides a route to antidepressants such as (−)-fluoxetine from (S)-ephedrine (see scheme; Cp*=η5-C5Me5, TBAT=tetrabutylammonium triphenyldifluorosilicate). Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2002/z18496_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
The humankind genome: from genetic diversity to the origin of human diseases (2013)

Genome-wide association studies have failed to establish common variant risk for the majority of common human diseases. The underlying reasons for this failure are explained by recent studies of resequencing and comparison of over 1200 human genomes and 10 000 exomes, together with the delineation of DNA methylation patterns (epigenome) and full characterization of coding and noncoding RNAs (transcriptome) being transcribed. These studies have provided the most comprehensive catalogues of functional elements and genetic variants that are now available for global integrative analysis and experimental validation in prospective cohort studies. With these datasets, researchers will have unparalleled opportunities for the alignment, mining, and testing of hypotheses for the roles of specific genetic variants, including copy number variations, single nucleotide polymorphisms, and indels as the cause of specific phenotypes and diseases. Through the use of next-generation sequencing technologies for genotyping and standardized ontological annotation to systematically analyze the effects of genomic variation on humans and model organism phenotypes, we will be able to find candidate genes and new clues for disease's etiology and treatment. This article describes essential concepts in genetics and genomic technologies as well as the emerging computational framework to comprehensively search websites and platforms available for the analysis and interpretation of genomic data.
Stimulation of DNA synthesis and c-fos mRNA expression in primary rat hepatocytes by estrogens (2001)

The mechanism(s) of tumour promotion in liver by estrogens is not well understood although growth stimulation is known to be one important element of their action. As a basis for studying mechanisms of growth control by estrogens, effects of both natural and synthetic estrogens on DNA synthesis and protooncogene c-fos mRNA expression were examined in primary cultures of normal rat hepatocytes. 17beta-Estradiol (E(2)) alone was stimulatory and exhibited dramatic synergism with epidermal growth factor (EGF) in stimulating DNA synthesis. All estrogens tested (natural, synthetic, steroidal and non-steroidal) exhibited an ability to stimulate hepatocyte DNA synthesis. This appears to correlate with their ability to induce c-fos mRNA expression. In contrast to a non-estrogenic liver tumour promoter, phenobarbital, insulin is not permissive for the growth-stimulatory action of E(2). Dexamethasone, which is required for stimulation of DNA synthesis by the non-estrogenic tumour promoter alpha-hexachlorocyclohexane and tetradecanoylphorbol acetate, completely blocked E(2)-stimulated DNA synthesis. Such differential requirements for auxiliary factors suggests that estrogen and other non-estrogenic liver tumour promoters act via distinct mechanisms in stimulating hepatocyte DNA synthesis. E(2) alone had no effect, but when in combination with EGF significantly induced c-fos mRNA expression at early times in culture (maximal at 10 h in culture). Such findings, coupled with the observations that (i) E(2) and EGF were synergistic in growth stimulation, (ii) estrogen receptor levels are higher at early times in culture and (iii) the growth-stimulatory ability of E(2) is limited to 4-24 h in culture, support the notion that in hepatocytes E(2) acts via the estrogen receptor to transactivate c-fos expression (an interaction with EGF), which ultimately culminates in enhanced DNA synthesis. Dexamethasone did not block E(2)-induced c-fos gene expression, suggesting that it acts in a pathway(s) distal to activation of fos gene expression. The possible inhibitory mechanisms of action of dexamethasone on E(2)-stimulated DNA synthesis are discussed.
The Feynman path integral approach to atomic interferometry. A tutorial (1994)

Many problems of current interest in atomic interferometry lend themselves to a path integral treatment. We present a practical guide to solving such problems, taking as examples the gravitational experiments of Kasevich and Chu, and the atomic equivalents of the Sagnac and Aharonov-Bohm effects.
Structure from Motion (SfM) Photogrammetry with Drone Data: A Low Cost Method for Monitoring Greenhouse Gas Emissions from Forests in Developing Countries (2017)

Structure from Motion (SfM) photogrammetry applied to photographs captured from Unmanned Aerial Vehicle (UAV) platforms is increasingly being utilised for a wide range of applications including structural characterisation of forests. The aim of this study was to undertake a first evaluation of whether SfM from UAVs has potential as a low cost method for forest monitoring within developing countries in the context of Reducing Emissions from Deforestation and forest Degradation (REDD+). The project evaluated SfM horizontal and vertical accuracy for measuring the height of individual trees. Aerial image data were collected for two test sites; Meshaw (Devon, UK) and Dryden (Scotland, UK) using a Quest QPOD fixed wing UAV and DJI Phantom 2 quadcopter UAV, respectively. Comparisons were made between SfM and airborne LiDAR point clouds and surface models at the Meshaw site, while at Dryden, SfM tree heights were compared to ground measured tree heights. Results obtained showed a strong correlation between SfM and LiDAR digital surface models (R2 = 0.89) and canopy height models (R2 = 0.75). However, at Dryden, a poor correlation was observed between SfM tree heights and ground measured heights (R2 = 0.19). The poor results at Dryden were explained by the fact that the forest plot had a closed canopy structure such that SfM failed to generate enough below-canopy ground points. Finally, an evaluation of UAV surveying methods was also undertaken to determine their usefulness and cost-effectiveness for plot-level forest monitoring. The study concluded that although SfM from UAVs performs poorly in closed canopies, it can still provide a low cost solution in those developing countries where forests have sparse canopy cover (<50%) with individual tree crowns and ground surfaces well-captured by SfM photogrammetry. Since more than half of the forest covered areas of the world have canopy cover <50%, we can conclude that SfM has enormous potential for forest mapping in developing countries.
Immunotherapy of Tumors with Protein Vaccine Based on Chicken Homologous Tie-2 (2006)

Our findings may provide a vaccine strategy for cancer therapy and show the potential utilization of interference with Tie-2 pathway.
Development and Evaluation of a Loop-Mediated Isothermal Amplification Method for Rapid Diagnosis of <i>Bordetella pertussis</i> Infection (2006)

We developed a loop-mediated isothermal amplification (LAMP) method to detect Bordetella pertussis infection. This LAMP assay detected B. pertussis with high sensitivity, but not other Bordetella species. Among nasopharyngeal swab samples from subjects with suspected pertussis, LAMP results showed a high level of agreement with results of conventional PCR. This method is a rapid, sensitive, and specific method for diagnosis of B. pertussis infection even in clinical laboratories with no specific equipment.
Magnetocaloric effects in <b> <i>RTX</i> </b> intermetallic compounds ( <b> <i>R</i> </b> = Gd–Tm, <b> <i>T</i> </b> = Fe–Cu and Pd, <b> <i>X</i> </b> = Al and Si) (2015)

The magnetocaloric effect (MCE) of RTSi and RT Al systems with R = Gd–Tm, T = Fe–Cu and Pd, which have been widely investigated in recent years, is reviewed. It is found that these RTX compounds exhibit various crystal structures and magnetic properties, which then result in different MCE. Large MCE has been observed not only in the typical ferromagnetic materials but also in the antiferromagnetic materials. The magnetic properties have been studied in detail to discuss the physical mechanism of large MCE in RTX compounds. Particularly, some RTX compounds such as ErFeSi, HoCuSi, HoCuAl exhibit large reversible MCE under low magnetic field change, which suggests that these compounds could be promising materials for magnetic refrigeration in a low temperature range.
From the Editor - 2011 (2011)

A letter from teh editor - Winter 2011
Evaluation of thrombin generating capacity in plasma from patients with haemophilia A and B (2005)

In haemophilia patients, a relationship is usually observed between the clinical expression of the disease and plasmatic factor VIII/factor IX (FVIII/FIX) activity. However, it is known from clinical experience, that some haemophilia patients, despite similar FVIII/FIX plasma levels, could exhibit different bleeding phenotype. After determining preanalytical test conditions, we evaluated the thrombin generation capacity from haemophilia plasma samples in various conditions and the potential usefulness of thrombin generation test (TGT) in haemophilia patients. In a series of 46 haemophilia patients (34 haemophilia A and 12 haemophilia B patients), we found a significant correlation between plasmatic FVIII/FIX levels and endogenous thrombin potential (ETP), peak and time to peak obtained by thrombin generation measurement. In addition, a correlation was found between severe clinical bleeding phenotype and ETP. Our results suggest that TGT could be a promising tool to evaluate haemostasis capacity in patients with haemophilia. Our ex vivo results, obtained 24 hours after FVIII concentrate administration, showed that in patients presenting similar plasmatic FVIIII levels, thrombin generation capacity may be significantly different. These results suggest that in patients with haemophilia, TGT could be useful for individually tailoring prophylactic regimens as well as for adapting clotting factors infusions in surgical situations, in addition to FVIII/FIX plasma clotting activities.
Modeling oscillator arrays for video analytic applications (2014)

Weakly coupled oscillators have shown promise as a computational building block that exploits the power of emerging low power high density nano-devices such as spin torque oscillators and vanadium oxide oscillators. In this paper, we develop a new analytic phase model as well as a circuit simulation to show how clusters and arrays of coupled oscillators can be inserted into three different stages of an image processing pipeline and provide comparable image recognition performance to traditional methods.
FRONT PAGES (2020)

1. Cover2. Editorial Team3. from the editor4. Table of Contents
Comparison of golimumab 100-mg monotherapy to golimumab 50 mg plus methotrexate in patients with rheumatoid arthritis: Results from a multicenter, cohort study (2015)

GLM 100 mg monotherapy improved disease activity as well as GLM 50 mg + MTX combination therapy. GLM 100 mg monotherapy appears to have a sufficient therapeutic effect in RA patients who cannot take MTX.
The role of<i>Pseudomonas aeruginosa</i>elastase as a potent inflammatory factor in a rat air pouch inflammation model (1999)

Pseudomonas aeruginosa, an opportunistic pathogen, can cause life threatening infections in patients compromised by underlying respiratory disease like bronchiectasis, cystic fibrosis and diffuse panbronchiolitis. Most strains of P. aeruginosa produce some kind of protease with broad substrate specificities during the infectious state in the host. P. aeruginosa elastase, one of the strongest exotoxins, has a tissue-damaging proteolytic activity and is capable of degrading such plasma proteins as immunoglobulins, complement factor and cytokines. The present study focused on the effect of P. aeruginosa elastase and was designed to evaluate the neutrophil accumulation at the inflammation site mediated by P. aeruginosa elastase in the inflammatory response in the host. An air pouch model in rats, considered as a useful model of inflammation, was used to analyze the number of leukocytes, the volume of exudate and the concentration of interleukin-8 after the injection of P. aeruginosa elastase into the pouch cavity. The number of neutrophils and the volume of exudate in the pouch cavity increased significantly at 4 h, peaked at 8 h in a dose-dependent manner and then decreased at 24 h. The concentration of interleukin-8 in pouch fluid peaked 4 h earlier than the peak of the neutrophil number. The enzymatic activity of P. aeruginosa elastase seemed to reinforce the inflammation process. The influence of lipopolysaccharide contamination was negligible. Although these observations were made in the subcutaneous cavity, they indicate that P. aeruginosa elastase plays a role as an immunoprovocative factor in the inflammatory response in cases of infection with P. aeruginosa.
Compact 160-Gb/s Add–Drop Multiplexer With a 40-Gb/s Base Rate Using Electroabsorption Modulators (2004)

We report on the first 40-Gb/s-based 160-Gb/s add-drop multiplexer (ADM) using a pair of standing-wave enhanced electroabsorption modulator (EAM). Direct time-domain switching is performed without interferometers or optical control pulses as required by previously reported approaches, which indicates great advantages in compactness for the EAM-based ADM. Also, a 40-Gb/s base rate is attractive in realizing a more efficient 160-Gb/s system. Error-free operation for all channels is obtained with an average power penalty as low as 1 dB.
Chemical bonding in amorphous Si-coated carbon nanotubes as anodes for Li ion batteries: a XANES study (2014)

The Si–O–C bonding and its evolution upon electrochemical cycling in a Si-coated carbon nanotube anode are unveiled by X-ray absorption spectroscopy studies.
Optimization of 16-APSK by Maximizing Mutual Information Criteria in SC-FDMA Communication Systems (2014)

Single Carrier Frequency Division Multiplexing (SC-FDMA) scheme has been considered to be promising technology for the uplink of the 4G mobile communication systems. The main disadvantage of SC-FDMA is the high envelope fluctuation of signal resulting in a presence of nonlinear distortion in transmitted signal due to the transmitter high power amplifier (HPA). In order to improve the SC-FDMA performance, the 16-ary Amplitude Phase Shift Keying (16-APSK) is proposed as a base-band modulation scheme for SC-FDMA instead of conventional M-QAM. The different types of 16-APSK modulations will be investigated and positions of constellation points will be optimized according to maximizing Mutual Information (MI) criteria. For given value of SNR will be found optimal 16-APSK modulation and it will be proposed adaptive approach of 16-APSK modulation. The performance properties of adaptive approach of 16-APSK and 16-QAM based SC-FDMA transmission scheme will be illustrated using numerical results. The obtained results will show that optimized 16-APSK modulation in SC-FDMA transmitted system provide better performance than 16-QAM SC-FDMA system if the nonlinear model of HPA has to be assumed.
Theoretical Speciation of Ethylenediamine-<i>N</i>-(<i>o</i>-hydroxyphenylacetic)-<i>N</i>‘-(<i>p</i>-hydroxyphenylacetic) Acid (<i>o</i>,<i>p</i>-EDDHA) in Agronomic Conditions (2003)

The presence of ethylenediamine-N-(o-hydroxyphenylacetic)-N'-(p-hydroxyphenylacetic) acid (o,p-EDDHA) as the second largest component in commercial EDDHA iron chelates has recently been demonstrated. Here is reported the speciation of o,p-EDDHA by the application of a novel methodology through the determination of the complexing capacity, protonation, and Ca(2+), Mg(2+), Cu(2+), and Fe(3+) stability constants. The pM values and species distribution in solution, hydroponic, and soil conditions were obtained. Due to the para position of one phenol group in o,p-EDDHA, the protonation constants and Ca and Mg stability constants have different values from those of o,o-EDDHA and p,p-EDDHA regioisomers. o,p-EDDHA/Fe(3+) stability constants are higher than those of EDTA/Fe(3+) but lower than those of o,o-EDDHA/Fe(3+). The sequence obtained for pFe is o,o-EDDHA/Fe(3+) >/= o,p-EDDHA/Fe(3+) > EDTA/Fe(3+). o,p-EDDHA/Fe(3+) can be used as an iron chelate in hydroponic conditions. Also, it can be used in soils with limited Cu availability.