gebhart/patrepeval huggingface dataset:
An Adaptive Droop DC-Bus Voltage Controller for a Grid-Connected Voltage Source Inverter With LCL Filter (2014)

This paper presents a very fast dc-bus voltage controller for a single-phase grid-connected voltage-source inverter (VSI) with an LCL output filter used in renewable energy applications. In single-phase grid-connected inverters, the design of the dc-bus voltage control scheme is very challenging due to the presence of a second harmonic ripple across the dc-bus voltage. The proposed dc-bus voltage control scheme is able to address the difficulties introduced by the second-harmonic ripple. The dc-bus voltage controller is based on an adaptive droop control technique, which is able to provide a very fast transient response for the closed-loop system and ensures the optimal operation of the VSI during steady-state conditions. Also, the simple structure of the controller makes it very practical for grid-connected VSIs used in renewable energy power conditioning systems. Theoretical analysis and experimental results demonstrate the superior performance of the proposed control approach compared to conventional dc-bus voltage control schemes.
Scanning Michelson interferometer for imaging surface acoustic wave fields (2000)

A scanning homodyne Michelson interferometer is constructed for two-dimensional imaging of high-frequency surface acoustic wave (SAW) fields in SAW devices. The interferometer possesses a sensitivity of ~10(-5)nm/ radicalHz , and it is capable of directly measuring SAW's with frequencies ranging from 0.5 MHz up to 1 GHz. The fast scheme used for locating the optimum operation point of the interferometer facilitates high measuring speeds, up to 50,000 points/h. The measured field image has a lateral resolution of better than 1 mu;m . The fully optical noninvasive scanning system can be applied to SAW device development and research, providing information on acoustic wave distribution that cannot be obtained by merely electrical measurements.
Free-Jet Testing of a REST Scramjet at Off-Design Conditions (2006)

Scramjet flowpaths employing elliptical combustors have the potential to improve structural efficiency and performance relative to those using planar geometries. NASA Langley has developed a scramjet flowpath integrated into a lifting body vehicle, while transitioning from a rectangular capture area to both an elliptical throat and combustor. This Rectangular-to-Elliptical Shape Transition (REST) scramjet, has a design point of Mach 7.1, and is intended to operate with fixed-geometry between Mach 4.5 and 8.0. This paper describes initial free-jet testing of the heat-sink REST scramjet engine model at conditions simulating Mach 5.3 flight. Combustion of gaseous hydrogen fuel at equivalence ratios between 0.5 and 1.5 generated robust performance after ignition with a silane-hydrogen pilot. Facility model interactions were experienced for fuel equivalence ratios above 1.1, yet despite this, the flowpath was not unstarted by fuel addition at the Mach 5.3 test condition. Combustion tests at reduced stagnation enthalpy indicated that the engine self-started following termination of the fuel injection. Engine data is presented for the largest fuel equivalence ratio tested without facility interaction. These results indicate that this class of three-dimensional scramjet engine operates successfully at off-design conditions.
PLinda 2.0: a transactional/checkpointing approach to fault tolerant Linda (2002)

Robust parallel computation in Linda requires both tuple space and processes to be resilient to failure. In this paper, we present PLinda 2.0, set of extensions to Linda to support robust parallel computation on loosely coupled processors communicating over a network. The principal extensions of PLinda 2.0 to Linda are transaction mechanisms for reliable tuple space and process-private logging mechanisms for resilient processes. The transaction mechanisms support two kinds of tuple space: stable tuple space always guaranteed to reflect state as of last committed transaction, and unstable tuple space protected by a transaction-consistent checkpoint. The process-private logging mechanisms are provided as tools for a process checkpointing scheme. These mechanisms allow the customization of checkpointing and recovery operations in each process to achieve low runtime overhead.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Performance-driven routing with multiple sources (1997)

Existing routing problems for delay minimization consider the connection of a single source node to a number of sink nodes, with the objective of minimizing the delay from the source to all sinks, or a set of critical sinks. In this paper, we study the problem of routing nets with multiple sources, such as those found in signal busses. This new model assumes that each node in a net may be a source, a sink, or both. The objective is to optimize the routing topology to minimize the total weighted delay between all node pairs (of a subset of critical node pairs). We present a heuristic algorithm for the multiple-source performance driven routing tree problem based on efficient construction of minimum diameter minimum-cost Steiner trees. Experimental results on random nets with submicrometer CMOS IC and MCM technologies show an average of 12.6% and 21% reduction in the maximum interconnect delay, when compared with conventional minimum Steiner tree based topologies. Experimental results on multisource nets extracted from an Intel processor show as much as a 16.1% reduction in the maximum interconnect delay, when compared with conventional minimum Steiner tree based topologies.
Optimal preparation of preimplantation embryo interphase nuclei for analysis by fluorescence in-situ hybridization (1994)

A new method was developed to prepare and isolate interphase nuclei from murine preimplantation embryos for analysis by fluorescence in-situ hybridization. Embryos were washed with phosphate-buffered saline and disaggregated in a small drop of bidistilled water containing HCl and Tween 20. During the disaggregation procedure embryos were watched continuously with an inverted microscope. Embryonic nuclei were digested with pepsin to make them accessible for hybridization to the probes and to remove remnants of cytoplasm. Nuclear and probe DNA were denatured simultaneously and hybridization was done overnight, followed by immunocytochemical detection of the probes. Using this method we were able to perform successful in-situ hybridization on all preimplantation stages of the mouse embryo (pronuclei, 2-cell, 4-cell, morula and blastocyst). Probes for the X and Y chromosomes were applied for sex determination. From the results described in this paper we conclude that the preparation and isolation of interphase nuclei from murine embryos with acid and Tween 20 offers high reproducibility, good morphology of the cells and a high hybridization efficiency.
Potent Fc Receptor Signaling by IgA Leads to Superior Killing of Cancer Cells by Neutrophils Compared to IgG (2019)

Antibody therapy of cancer is increasingly used in the clinic and has improved patient's life expectancy. Except for immune checkpoint inhibition, the mode of action of many antibodies is to recognize overexpressed or specific tumor antigens and initiate either direct F(ab')<sub>2</sub>-mediated tumor cell killing, or Fc-mediated effects such as complement-dependent cytotoxicity (CDC) and antibody-dependent cell-mediated cytotoxicity/phagocytosis (ADCC/P) after binding to activating Fc receptors. All antibodies used in the clinic are of the IgG isotype. The IgA isotype can, however, also elicit powerful anti-tumor responses through engagement of the activating Fc receptor for monomeric IgA (FcαRI). In addition to monocytes, macrophages and eosinophils as FcαRI expressing immune cells, neutrophils are especially vigorous in eliminating IgA opsonized tumor cells. However, with IgG as single agent it appears almost impossible to activate neutrophils efficiently, as we have visualized by live cell imaging of tumor cell killing. In this study, we investigated Fc receptor expression, binding and signaling to clarify why triggering of neutrophils by IgA is more efficient than by IgG. FcαRI expression on neutrophils is ~2 times and ~20 times lower than that of Fcγ receptors FcγRIIa and FcγRIIIb, but still, binding of neutrophils to IgA- or IgG-coated surfaces was similar. In addition, our data suggest that IgA-mediated binding of neutrophils is more stable compared to IgG. IgA engagement of neutrophils elicited stronger Fc receptor signaling than IgG as indicated by measuring the p-ERK signaling molecule. We propose that the higher stoichiometry of IgA to the FcαR/FcRγ-chain complex, activating four ITAMs (Immunoreceptor Tyrosine-based Activating Motifs) compared to a single ITAM for FcγRIIa, combined with a possible decoy role of the highly expressed FcγRIIIb, explains why IgA is much better than IgG at triggering tumor cell killing by neutrophils. We anticipate that harnessing the vast population of neutrophils by the use of IgA monoclonal antibodies can be a valuable addition to the growing arsenal of antibody-based therapeutics for cancer treatment.
ETA and ETB Receptors Modulate the Proliferation of Human Pulmonary Artery Smooth Muscle Cells (2002)

We determined the distribution of ET(A) and ET(B) receptors in pulmonary arteries from pulmonary hypertensive patients and control subjects, using in vitro autoradiography, and investigated their role in mediating the proliferative effects of endothelin-1 (ET-1) on distal human pulmonary artery smooth muscle cells (PASMCs). Distal arteries possessed more medial [(125)I]-ET-1 binding sites (105 +/- 10 versus 45 +/- 6 amol/mm(2); p < 0.001) and a greater proportion of ET(B) receptors than proximal arteries (36 +/- 3% versus 3 +/- 1%; p < 0.001). Receptor density in distal arteries and lung parenchyma was twofold greater (p < 0.05) in pulmonary hypertensive patients than in control subjects. ET-1 (10(-9)-10(-7) mol/L) stimulated DNA synthesis (147 +/- 10% of control subjects; p < 0.05) and attenuated the antiproliferative action of cicaprost and forskolin on PASMCs, these effects being mediated via ET(A) and ET(B) receptors. Serum-stimulated proliferation was attenuated by inhibiting either endogenous ET-1 release with phosphoramidon (10(-5) mol/L) or its action with PD145065 (10(-5) mol/L). Cicaprost (10(-10)-10(-7) mol/L) inhibited ET-1 release from PASMCs (49 +/- 16% of control after 24 h; p < 0.001) and increased intracellular cAMP levels, whereas ET(B) receptor stimulation selectively reduced cAMP levels. In conclusion, ET(A) and ET(B) receptors are differentially distributed in human pulmonary arteries. Both receptors promote the proliferation of PASMCs in vitro and may contribute to vascular remodeling in pulmonary hypertension.
DAVO: A Domain-Adaptable, Visual BPEL4WS Orchestrator (2009)

The Business Process Execution Language for Web Services (BPEL4WS) is the de facto standard for the composition of web services into complex, valued-added workflows in both industry and academia. Since the composition of web services into a workflow is challenging and error-prone, several graphical BPEL4WS workflow editors have been developed. These tools focus on the composition process and the visualization of workflows and mainly address the needs of web service experts.To increase the acceptance of BPEL4WS in new application domains, it is mandatory that non web service experts are also empowered to easily compose web services into a workflow. This paper presents the Domain-Adaptable Visual Orchestrator (DAVO), a graphical BPEL4WS workflow editor which offers a domain-adaptable data model and user interface. DAVO can be easily customized to domain needs and thus is suitable for non web service experts.
Fat quantification using multiecho sequences with bipolar gradients: Investigation of accuracy and noise performance (2013)

The bipolar technique was found to provide accurate fat quantification with noise performance similar to the unipolar technique given an appropriate choice of inter-echo time.
Bubble oscillations of large amplitude (1980)

A new equation is derived for large amplitude forced radial oscillations of a bubble in an incident sound field. It includes the effects of acoustic radiation, as in Keller and Kolodner’s equation, and the effects of viscosity and surface tension, as in the modified Rayleigh equation due to Plesset, Noltingk and Neppiras, and Poritsky. The free and forced periodic solutions are computed numerically. For large bubbles, such as underwater explosion bubbles, the free oscillations agree with those obtained by Keller and Kolodner. For small bubbles, such as cavitation bubbles, with small or intermediate forcing amplitudes, the results agree with those calculated by Lauterborn from the modified Rayleigh equation of Plesset et al. For large forcing amplitudes that equation yielded unsatisfactory results whereas the new equation yields quite satisfactory ones.
BADGR: A practical GHR implementation for TAGE branch predictors (2016)

In this work, we explore global history register (GHR) implementations for Tagged Geometric length (TAGE) style branch predictors with speculative updates. We break down the requirements to both update and recover TAGE predictors' history registers during normal operation and after mispeculation, discussing where various designs exhibit large checkpoint and/or operation overheads. To reduce these inefficiencies, we introduce BADGR, a novel GHR design for TAGE predictors that lowers power consumption and chip area over naive checkpointing techniques by 90% and 85%, respectively.
Multi-hop path splitting and multi-pathing optimizations for data transfers over shared wide-area networks using gridFTP (2008)

In this paper, we propose to employ two optimizations - multi-hop path splitting and multi-pathing - to improve the performance of data transfers over shared public networks. We present a path determination algorithm which integrates the aforesaid optimizations in order to improve the performance of single file transfers. Finally, we develop a file transfer scheduling algorithm based on this framework, and evaluate its effectiveness on a wide-area testbed.
Fine-grained dynamic instrumentation of commodity operating system kernels (1999)

We have developed a technology, fine-grained dynamic instrumentation of commodity kernels, which can splice (insert) dynamically generated code before almost any machine code instruction of a completely unmodified running commodity operating system kernel. This technology is well-suited to performance profiling, debugging, code coverage, security auditing, runtime code optimizations, and kernel extensions. We have designed and implemented a tool called Kernlnst that performs dynamic instrumentation on a stock production Solaris kernel running on an UltraSPARC, On top of KernInst, we have implemented a kernel performance profiling tool, and used it to understand kernel and application performance under a Web proxy server workload. We used this information to make two changes (one to the kernel, one to the proxy) that cumulatively reduce the percentage of elapsed time that the proxy spends opening disk cache files from 40% to 7%.
VeDi: A vehicular crowd-sourced video social network for VANETs (2014)

As one of the important members of Internet of Things (IoT), vehicles have seen steep advancement in communication technology.With the advent of Vehicular Ad-Hoc Networks (VANETs), vehicles now can evolve into social interactions to share safety, efficiency, and comfort related messages with other vehicles. In this paper, we study vehicular social network from Social Internet of Things (SIoT) perspective and propose VeDi, a vehicular crowd-sourced video social network for VANETs.When a user shares a video in the VeDi, it can be accessed by other surrounding vehicles. Any social interaction (e.g. view, comment, like) with the video on the roadway are stored in the social network cloud along with the video itself. In VeDi, every vehicle maintains a list of video related metadata (e.g. blur and shakiness) of available videos which are used to selectively retrieve quality videos by surrounding vehicles. We also present a method to determine representative quality scores for an entire video clip using blur and shakiness values. The prototype implementations and experimental results denote that the proposed system can be a viable option to create video social networks such as youtube, vine, and vimeo by employing vehicular crowd.
Sailing the Information Ocean with Awareness of Currents: Discovery and Application of Source Dependence (2009)

The Web has enabled the availability of a huge amount of useful information, but has also eased the ability to spread false information and rumors across multiple sources, making it hard to distinguish between what is true and what is not. Recent examples include the premature Steve Jobs obituary, the second bankruptcy of United airlines, the creation of Black Holes by the operation of the Large Hadron Collider, etc. Since it is important to permit the expression of dissenting and conflicting opinions, it would be a fallacy to try to ensure that the Web provides only consistent information. However, to help in separating the wheat from the chaff, it is essential to be able to determine dependence between sources. Given the huge number of data sources and the vast volume of conflicting data available on the Web, doing so in a scalable manner is extremely challenging and has not been addressed by existing work yet. In this paper, we present a set of research problems and propose some preliminary solutions on the issues involved in discovering dependence between sources. We also discuss how this knowledge can benefit a variety of technologies, such as data integration and Web 2.0, that help users manage and access the totality of the available information from various sources.
Phase II Study of Gemcitabine and Oxaliplatin in Combination With Bevacizumab in Patients With Advanced Hepatocellular Carcinoma (2006)

GEMOX-B could be safely administered with close monitoring and had moderate antitumor activity for patients with advanced HCC. The high 6-month PFS rate is encouraging, and this regimen is worthy of further investigation.
Targeting the Inflammatory Pathway as a Therapeutic Tool for Major Depression (2014)

In the last decades convergent findings from several lines of evidence has revealed a robust association between major depressive disorder (MDD) and inflammatory pathways. Despite this, the translation of these findings into new and better treatments for MDD has not occurred. The objective of this study is to comprehensively review what is already known with reasonable certainty on inflammatory pathways in MDD, to clarify some points that have been insufficiently studied and to discuss the implications of these findings for future studies targeting inflammatory pathways as a therapeutic tool for individuals with MDD.
Characterizations of MONOS structures with a superthin nitride film for the low voltage NVSM using TSC techniques (2002)

TSC (thermally stimulated current) technique has been applied to investigate the characteristics of MONOS (metal-oxide-nitride-oxide-semiconductor) structures with superthin nitride film of 46 /spl Aring/ thick for the low voltage NVSM. A new discharging model bans been developed and formulated for analysis of TSC curves due to memory traps such as the blocking oxide-nitride interface trap and the nitride bulk trap. By best fitting method, the blocking oxide-nitride interface traps are found to be energetically distributed in the range of 1.17/spl sim/1.18 eV below the top of the nitride conduction band with a density of N/sub ON/=2.3/spl times/10/sup 15/ cm/sup -2/ eV/sup -1/. The discharging mechanism can be explained that the holes trapped in the blocking oxide-nitride interface traps, distributed uniformly in energy, are first thermally excited into the nitride valence band, then drifted to the nitride-tunneling oxide interface, and finally tunneled into the Si valence band to contribute to TSC.
Evaluating the Competing Assumptions of Gottfredson and Hirschi's (1990) A General Theory of Crime and Psychological Explanations of Agression (2005)

Gottfredson and Hirschi’s (1990) A General Theory of Crime, argues individual criminal propensity manifests itself as a general tendency to engage in a variety of criminal and delinquent acts. In contrast, Psychological explanations of aggression assume that the causal processes explaining individual variation in aggression are somehow different from those explaining other forms of crime and deviance. The current work assessed the relative strength of the assumptions of these two positions by testing the relationships among hostile attributional bias, selfcontrol, and three indicators of criminal intent. Hostile attributional bias is an individual characteristic important in psychological research on social information processing models of aggression. As defined by Gottfredson and Hirschi (1990), self-control represents a general tendency towards a variety of criminal and delinquent acts. Results support the assumptions of both general theories and act-specific explanations of aggression. When demographic control variables and self-control are accounted for, hostile attributional bias is uniquely associated with aggressive intent. However, when compared to hostile attributional bias, self-control explains a larger amount of variation in all intent measures including aggression.
Global Genetic Structure and Molecular Epidemiology of Encapsulated Haemophilus influenzae (1990)

A collection of 2,209 isolates of six polysaccharide capsule types of Haemophilus influenzae, including 1,975 serotype b isolates recovered in 30 countries was characterized for electrophoretically demonstrable allele profiles at 17 metabolic enzyme loci. Two hundred eighty distinct multilocus genotypes were distinguished, and cluster analysis revealed two primary phylogenetic divisions. The population structure of encapsulated H. influenzae is clonal. Currently, most of the invasive disease worldwide is caused by serotype b strains of nine clones. Strains producing serotype c, e, and f capsules belong to single divisions and have no close genetic relationships to strains of other serotypes. Serotype a and b strains occur in both primary phylogenetic divisions, probably as a result of transfer and recombination of serotype-specific sequences of the cap region between clonal lineages. A close genetic relatedness between serotype d isolates and some strains of serotypes a and b was identified. There are strong patterns of geographic variation, on an intercontinental scale, in both the extent of genetic diversity and the clonal composition of populations of encapsulated strains. The analysis suggests that the present distribution of clones is, in part, related to patterns of racial or ethnic differentiation and historical demographic movements of the human host populations.
The hB-tree: a multiattribute indexing method with good guaranteed performance (1990)

A new multiattribute index structure called the hB-tree is introduced. It is derived from the K-D-B-tree of Robinson [15] but has additional desirable properties. The hB-tree internode search and growth processes are precisely analogous to the corresponding processes in B-trees [1]. The intranode processes are unique. A k-d tree is used as the structure within nodes for very efficient searching. Node splitting requires that this k-d tree be split. This produces nodes which no longer represent brick-like regions in k-space, but that can be characterized as holey bricks, bricks in which subregions have been extracted. We present results that guarantee hB-tree users decent storage utilization, reasonable size index terms, and good search and insert performance. These results guarantee that the hB-tree copes well with arbitrary distributions of keys.