gebhart/patrepeval huggingface dataset:
Pincer and Diamine Ru and Os Diphosphane Complexes as Efficient Catalysts for the Dehydrogenation of Alcohols to Ketones (2011)

The ruthenium and osmium complexes [MCl(2)(diphosphane)(L)] (M=Ru, Os; L=bidentate amino ligand) and [MCl(CNN)(dppb)] (CNN=pincer ligand; dppb=1,4-bis-(diphenylphosphino)butane), containing the N−H moiety, have been found to catalyze the acceptorless dehydrogenation of alcohols in tBuOH and in the presence of KOtBu. The compounds trans-[MCl(2)(dppf)(en)] (M=Ru 7, Os 13; dppf=1,1'-bisdiphenylphosphino)ferrocene; en=ethylenediamine) display very high activity and different substrates, including cyclic and linear alcohols, are efficiently oxidized to ketones by using 0.8-0.04 mol % of catalyst. The effect of the base and the comparison of the catalytic activity of the Ru versus Os complexes are reported. The ruthenium complex 7 generally leads to a faster conversion into ketones with respect to the osmium complex 13, which displays better activity in the dehydrogenation of 5-en-3β-hydroxy steroids. The synthesis of new Ru and Os complexes [MCl(2)(PP)(L)] (PP=dppb, dppf; L=(±)-trans-1,2-diaminocyclohexane,2-(aminomethyl)pyridine, and 2-aminoethanol) of trans and cis configuration is also reported.
FastRoute 2.0: A High-quality and Efficient Global Router (2007)

Because of the increasing dominance of interconnect issues in advanced IC technology, it is desirable to incorporate global routing into early design stages to get accurate interconnect information. Hence, high-quality and fast global routers are in great demand. In this paper, we propose two major techniques to improve the extremely fast global router, FastRoute (Pan and Chu, 2006) in terms of solution quality : (1) monotonic routing, (2) multi-source multi-sink maze routing. The new router is called FastRoute 2.0. Experimental results show that FastRoute 2.0 can generate high-quality routing solutions with fast runtime compared with three state-of-the-art academic global routers FastRoute, Labyrinth (Kastner et al., 2000) and Chi Dispersion router (Hadsell and Madden, 2003). On the set of benchmarks used in Pan and Chu, 2006 and Hadsell and Madden (2003), the total overflow of FastRoute 2.0 is 98, compared to 1012 (FastRoute), 2846 (Labyrinth) and 1271 (Chi Dispersion Router). The runtime of FastRoute 2.0 is 73% slower than FastRoute, but 78times and 37times faster than Labyrinth and Chi Dispersion router. The promising results make it possible to integrate global routing into early design stages. This could dramatically improve the design solution quality.
Pyrolysis of the tosylhydrazone sodium salts of two bicyclic lactones (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPyrolysis of the tosylhydrazone sodium salts of two bicyclic lactonesSemiramis Ayral-Kaloustian and William C. AgostaCite this: J. Org. Chem. 1982, 47, 2, 284–287Publication Date (Print):January 1, 1982Publication History Published online1 May 2002Published inissue 1 January 1982https://pubs.acs.org/doi/10.1021/jo00341a020https://doi.org/10.1021/jo00341a020research-articleACS PublicationsRequest reuse permissionsArticle Views170Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Low-cost and efficient logo insertion scheme in MPEG video transcoding (2002)

In this paper, we work on the problem of inserting logo into part of a previously compressed video sequence while transcoding it to a video stream with lower rate. In most of the transcoding architecture, it has been widely accepted to reuse the motion information extracted from the original incoming bit stream. For our transcoding and logo insertion process, we preserve the same motion information as the incoming video stream for the parts that were unaffected by logo, and propose an efficient algorithm to code logo areas. We first find the proper range of pictures that might be affected by logo insertions, analyze logo-affected parts of those pictures, and perform corresponding algorithms depending on the picture types. In addition, we develop a method to achieve better bit allocation during logo insertion. The efficiency of our algorithm is demonstrated by simulation.
Stabile, selbstorganisierte, äquilibrierende Katalysatoren für Grüne Chemie (2004)

Weniger anfällige Katalysatoren für Oxidationen werden durch Selbstorganisation stabiler Vorstufen unter Katalysebedingungen erhalten. Der beschriebene Polyoxometallat(POM)-Epoxidierungs-Katalysator ist schnell, selektiv und sicher – und das unter umweltfreundlichen Bedingungen. Das selbstorganisierende System ist ein wichtiger Schritt in Richtung grüner Katalyse (siehe Schema).
Purification and characterization of hormone-regulated isoforms of the regulatory subunit of type II cAMP-dependent protein kinase from rat ovaries. (1985)

The regulatory subunit (R-II) of cAMP-dependent protein kinase type II is induced in rat ovarian granulosa cells by the synergistic actions of estradiol and follicle-stimulating hormone. The R-II from rat ovaries was compared with R-II from rat heart, rat brain, bovine heart, and bovine brain using immunological methods, 8-N3[32P]cAMP photoaffinity labeling and sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Three isoforms of R-II were identified in rat ovarian cell extract (R-II54 Mr = 54,000, R-II52 Mr = 52,000, R-II51 Mr = 51,000), two isoforms of R-II in rat brain cell extract (Mr = 54,000, Mr = 52,000), and one isoform of R-II in rat heart cell extract (Mr = 54,000). Rat ovarian R-II54, heart R-II, and brain R-II (Mr = 54,000) were recognized by antiserum against rat heart R-II, whereas rat ovarian R-II52/R-II51 and rat brain R-II (Mr = 52,000) were not. In contrast, an antiserum raised against bovine heart R-II recognized all three isoforms of ovarian R-II as well as the lower molecular weight form of rat brain R-II. Ovarian types R-II52 and R-II51 but not R-II54 were increased selectively in granulosa cells by estradiol and follicle-stimulating hormone. In addition: 1) ovarian R-II52/51 subunits were purified to homogeneity and shown to recombine with C subunit from bovine heart to form a cAMP-dependent protein kinase; 2) pure R-II52/51 were not interconvertible to a higher molecular weight form by C subunit-dependent phosphorylation; 3) pure rat heart R-II (Mr = 54,000) and ovarian R-II52/51 exhibited distinct differences based on one- and two-dimensional peptide mapping; and 4) by two-dimensional sodium dodecyl sulfate-polyacrylamide gel electrophoresis pure R-II52/51 were resolved as three (rather than two) isoelectric variants which were clearly different from pure rat heart R-II54. Thus, the hormone-regulated form of R-II in rat ovarian granulosa cells appears to represent a gene product distinct from R-II54 in rat heart.
Refractive indices of lithium niobate as a function of wavelength and composition (1993)

An interferometric method is applied to determine the refractive indices of lithium niobate single crystals over a wide wavelength and composition range. A generalized two term Sellmeier equation is proposed that describes the refractive indices as a function of wavelength and stoichiometry. On the basis of this generalized Sellmeier equation the parameters of nearly all optical characterization methods for LiNbO3 can be calculated. By means of a Kramers–Kronig analysis the shift in the UV absorption edge and the change in the extraordinary refractive index with the composition can be referred to each other. Excellent agreement is found with the respective experimental values.
Preparation of a Novel Macroporous Silica-based Diglycolamide Derivative-impregnated Polymeric Composite and its Adsorption Mechanism for Rare Earth Metal Ions (2007)

Diethylenetriaminepentaacetic acid (DTPA), a multi-dentate acidic chelating agent containing five carboxyl and three amine groups all capable of protonation, is a pentabasic acid. To separate minor actinide [MA(III)] and rare earth [RE(III)] elements effectively from a HNO 3 solution containing DTPA generated in the MAREC process, a functional polymeric composite impregnated with a novel macroporous silica-based diglycolamide compound, N,N,N′,N′-tetraoctyl-3-oxapentane-1,5-diamide (TODGA), was prepared. Thus, the impregnated functional polymeric composite (TODGA/SiO 2 -P) was obtained by impregnating and immobilizing TODGA molecules in the pores of the SiO 2 -polymer (SiO 2 -P) particles (ca. 50 μm diameter) via a vacuum sucking technique. The effects of H + ions within the concentration range 0.01–3.0 M and of NO 3 − ions within the range 0.1–3.115 M on the adsorption of RE(III) ions onto TODGA/SiO 2 -P were investigated at 298 K. It was found that in the presence of 0.05 M DTPA, the DTPA species strongly affected the adsorption of RE(III) ions. The adsorption capability of TODGA/SiO 2 -P depended on the competitive reactions of RE(III) ions with two species, viz. H 4 DTPA − and H 2 DTPA 3− . The distribution coefficient (K d ) for RE(III) ions increased with increasing NO 3 − concentration, with one RE(III) ion reacting with two NO 3 − ions. The adsorption mechanism of RE(III) ions towards the TODGA/SiO 2 -P polymeric composite in HNO 3 solution containing 0.05 M DTPA was suggested as: [Formula: see text] The formation of H 4 DTPA − and RE(H 4 DTPA)(NO 3 ) 2 which are both capable of adsorbing with TODGA/SiO 2 -P was the main reason why RE(III) ions exhibited such significant adsorption in the presence of 0.05 M DTPA.
Recurrence of nephrotic syndrome after transplantation in a mixed population of children and adults: course of glomerular lesions and value of the Columbia classification of histological variants of focal and segmental glomerulosclerosis (FSGS) (2009)

In conclusion, the Columbia classification is of no help in predicting recurrence after renal transplantation or histological lesions in the case of recurrence of proteinuria.
Analytical modeling of an active noise control system in a duct (1987)

Making use of the transfer matrices and electroacoustic analogies, a standing wave analysis of the active noise control system in a duct is presented incorporating the characteristics of the primary source, as well as the auxiliary source. Analytical expressions have thus been derived for the ratio of the two source pressures and certain other ratios or relations of interest for complete cancellation of noise downstream of the auxiliary source. These expressions are then compared with those obtained from transfer functions of the various blocks constituting the block diagram of the entire system. In the process, equivalence has been established between the different entities involved in the two approaches, one of which is used in acoustics and the other in system theory. In particular, it has been shown that the pressure generated by a source against a load impedance can be looked upon as a sum of two pressure waves, one generated by the source against the characteristic impedance and the other by reflecting the rearward wave (incident on the source) off the source impedance. This principle is seminal in linking the two approaches.
Explaining Anomalies in Groups with Characterizing Subspace Rules (2017)

Anomaly detection has numerous applications and has been studied vastly. We consider a complementary problem that has a much sparser literature: anomaly description. Interpretation of anomalies is crucial for practitioners for sense-making, troubleshooting, and planning actions. To this end, we present a new approach called x-PACS (for eXplaining Patterns of Anomalies with Characterizing Subspaces), which "reverse-engineers" the known anomalies by identifying (1) the groups (or patterns) that they form, and (2) the characterizing subspace and feature rules that separate each anomalous pattern from normal instances. Explaining anomalies in groups not only saves analyst time and gives insight into various types of anomalies, but also draws attention to potentially critical, repeating anomalies. In developing x-PACS, we first construct a desiderata for the anomaly description problem. From a descriptive data mining perspective, our method exhibits five desired properties in our desiderata. Namely, it can unearth anomalous patterns (i) of multiple different types, (ii) hidden in arbitrary subspaces of a high dimensional space, (iii) interpretable by the analysts, (iv) different from normal patterns of the data, and finally (v) succinct, providing the shortest data description. Furthermore, x-PACS is highly parallelizable and scales linearly in terms of data size. No existing work on anomaly description satisfies all of these properties simultaneously. While not our primary goal, the anomalous patterns we find serve as interpretable "signatures" and can be used for detection. We show the effectiveness of x-PACS in explanation as well as detection on real-world datasets as compared to state-of-the-art.
Relationships between UBE3A and SNORD116 expression and features of autism in chromosome 15 imprinting disorders (2020)

Chromosome 15 (C15) imprinting disorders including Prader-Willi (PWS), Angelman (AS) and chromosome 15 duplication (Dup15q) syndromes are severe neurodevelopmental disorders caused by abnormal expression of genes from the 15q11-q13 region, associated with abnormal DNA methylation and/or copy number changes. This study compared changes in mRNA levels of UBE3A and SNORD116 located within the 15q11-q13 region between these disorders and their subtypes and related these to the clinical phenotypes. The study cohort included 58 participants affected with a C15 imprinting disorder (PWS = 27, AS = 21, Dup15q = 10) and 20 typically developing controls. Semi-quantitative analysis of mRNA from peripheral blood mononuclear cells (PBMCs) was performed using reverse transcription droplet digital polymerase chain reaction (PCR) for UBE3A and SNORD116 normalised to a panel of internal control genes determined using the geNorm approach. Participants completed an intellectual/developmental functioning assessment and the Autism Diagnostic Observation Schedule-2nd Edition. The Dup15q group was the only condition with significantly increased UBE3A mRNA levels when compared to the control group (p < 0.001). Both the AS and Dup15q groups also had significantly elevated SNORD116 mRNA levels compared to controls (AS: p < 0.0001; Dup15q: p = 0.002). Both UBE3A and SNORD116 mRNA levels were positively correlated with all developmental functioning scores in the deletion AS group (p < 0.001), and autism features (p < 0.001) in the non-deletion PWS group. The findings suggest presence of novel interactions between expression of UBE3A and SNORD116 in PBMCs and brain specific processes underlying motor and language impairments and autism features in these disorders.
Relative importance of direct and indirect dissociative recombination for polyatomic ions (1991)

Indirect dissociative recombination is unimportant compared with direct dissociative recombination because it depends on a breakdown of the Born-Oppenheimer approximation and there are consequential restrictions on the changes in the normal vibrational modes of the system.
Rapid and sensitive immunomagnetic-electrochemiluminescent detection of P53 protein from human lung cancer cell (2002)

In this work, we have designed an electrochemiluminescence (ECL) reaction system used to indicate P53 protein from human lung cancer cells. And we optimized the working electrode firstly in this experiment. The electrochemiluminescence magnetic immunoassay is quantitative, reproducible, and requires only minimal sample processing. A single photon counter was used to heighten the ECL detection limit. The homologous immunoassay format consisted of a double antibody sandwich in which a biotinylated capture antibody, pre-bound to streptavidin-coated magnetic beads, was used to bind antigen from test samples. A detector antibody, labeled with ruthenium( II ) tris-bipyridal chelate, was added and, when bounded to the bead immunocomplex, light was generated in the presence of an excess of tripropylamine. The light was detected and measured by the ECL reaction system we designed. High-sensitive, rapid and reproducible detection of tumor marker P53 protein was actualize with this detection system. The results showed that the electrode with many holes on it can enhance the ECL efficiency, so the detection limit of the system can be improved to 1/1000 fmol/L free labeled Ru(bpy)32+. Ru(bpy)32 + TPA(tripropylmine) ECL reaction system was used to indicate P53 protein from human lung cancer cells. This method could have potential applications in early-stage tumor diagnosis and environmental inspection.
Learning Through Play, the Old School Way: Teaching Information Ethics to Millennials (2014)

Incorporating gaming and active learning elements into library instruction in academic libraries has proven to be an effective way to engage Millennials and increase their retention of knowledge. This article ties research on the learning preferences of Millennials to elements of active and game-based learning. The author describes the process of creating an innovative game based on Candy Land to teach undergraduates about information ethics and makes recommendations for creating non-digital games for instructional purposes based on this experience.
Characteristics of offset-structure polycrystalline-silicon thin-film transistors (1988)

In order to reduce anomalous leakage current from n-channel polycrystalline-silicon thin-film transistors (poly-Si TFTs), an offset structure that has an n/sup -/ region between channel and n/sup +/ source-drain electrodes has been proposed. Drain-current measurements of the poly-Si TFT prove that the offset structure is effective in reducing the anomalous leakage current, and that the optimization of the offset length and the doping concentration in the offset region enlarge the ON/OFF current ratio. Implantation of 5*10/sup 13/ cm/sup -2/ phosphorus ions in the offset region makes the ON/OFF current ratio more than one order of magnitude larger than that of conventional structure TFTs.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Pharmacological removal of serum amyloid P component from intracerebral plaques and cerebrovascular Aβ amyloid deposits<i>in vivo</i> (2016)

Human amyloid deposits always contain the normal plasma protein serum amyloid P component (SAP), owing to its avid but reversible binding to all amyloid fibrils, including the amyloid β (Aβ) fibrils in the cerebral parenchyma plaques and cerebrovascular amyloid deposits of Alzheimer's disease (AD) and cerebral amyloid angiopathy (CAA). SAP promotes amyloid fibril formation in vitro, contributes to persistence of amyloid in vivo and is also itself directly toxic to cerebral neurons. We therefore developed (R)-1-[6-[(R)-2-carboxy-pyrrolidin-1-yl]-6-oxo-hexanoyl]pyrrolidine-2-carboxylic acid (CPHPC), a drug that removes SAP from the blood, and thereby also from the cerebrospinal fluid (CSF), in patients with AD. Here we report that, after introduction of transgenic human SAP expression in the TASTPM double transgenic mouse model of AD, all the amyloid deposits contained human SAP. Depletion of circulating human SAP by CPHPC administration in these mice removed all detectable human SAP from both the intracerebral and cerebrovascular amyloid. The demonstration that removal of SAP from the blood and CSF also removes it from these amyloid deposits crucially validates the strategy of the forthcoming 'Depletion of serum amyloid P component in Alzheimer's disease (DESPIAD)' clinical trial of CPHPC. The results also strongly support clinical testing of CPHPC in patients with CAA.
Subclinical Disease as an Independent Risk Factor for Cardiovascular Disease (1995)

The measurement of subclinical disease provides an approach for identifying high-risk older individuals who may be candidates for more active intervention to prevent clinical disease.
Early Cardiac Tamponade in a Patient with Postsurgical Hypothyroidism (2015)

Pericardial effusion is a common cardiac manifestation of hypothyroidism, but effusion resulting in cardiac tamponade is extremely rare. We present a case of a 56-year-old African American woman with slurred speech and altered mental status that was initially suspected to have stroke. Her chest X-ray revealed cardiomegaly and subsequent echocardiogram showed a large pericardial effusion with echocardiographic evidence of cardiac tamponade. Clinically, patient did not have pulsus paradoxus or hypotension. Further questioning revealed a history of total surgical thyroidectomy and noncompliance with thyroid replacement therapy. Pericardiocentesis was performed promptly and thyroxine replacement therapy was started. Thereafter, her mental status improved significantly. The management of pericardial effusion associated with hypothyroidism varies depending on size of effusion and hemodynamic stability of the patient. The management strategy ranges from conservative management with close monitoring and thyroxine replacement to pericardiocentesis or creation of a pericardial window.