gebhart/patrepeval huggingface dataset:
A Case Study Of IOI Plantations (2008)

This case study diagnoses IOI internal and external environments of the company and benchmarking IOI performance versus its industry competitors. In addition, this study also seeks to evaluate business strategies that IOI employs and outline strategic plans that are required to reposition itself in strive to maintain competitiveness, sustaining growth and thus generating greater profits.
The DF-dice storage element for immunity to soft errors (2005)

This paper describes the delay filtered dual interlocked storage cell, which is immune to single event transients on any of the inputs and single event upsets within the storage cell. The increase in area and speed of an application specific integrated circuit (ASIC) employing the proposed cells are proportional to the targeted single-event transient (SET) pulse-width. A standard ASIC can easily be converted to a soft-error tolerant design by simply replacing all the storage elements with the proposed cells. The area and speed performance of the proposed cells targeted for an 800ps wide SET have been evaluated. The resulting designs are immune to soft-errors with acceptable area penalty and modest degradation in speed.
Neural-Network Optimized 1-bit Precoding for Massive MU-MIMO (2019)

Base station (BS) architectures for massive multiuser (MU) multiple-input multiple-output (MIMO) wireless systems are equipped with hundreds of antennas to serve tens of users on the same time-frequency channel. The immense number of BS antennas incurs high system costs, power, and interconnect bandwidth. To circumvent these obstacles, sophisticated MU precoding algorithms that enable the use of 1-bit DACs have been proposed. Many of these precoders feature parameters that are, traditionally, tuned manually to optimize their performance. We propose to use deep-learning tools to automatically tune such 1-bit precoders. Specifically, we optimize the biConvex 1-bit PrecOding (C2PO) algorithm using neural networks. Compared to the original C2PO algorithm, our neural-network optimized (NNO-)C2PO achieves the same error-rate performance at 2× lower complexity. Moreover, by training NNO-C2PO for different channel models, we show that 1-bit precoding can be made robust to vastly changing propagation conditions.
Experimental evidence for effects of magnetic fields on moving water (1985)

Observable changes of water by magnetic fields have been investigated in an attempt to contribute to the knowledge of the structure of liquid water. The crystallization mode of the water's mineral content was found to change from a dendritic, substrate-bound solidification habit to the form of separate disc-shaped crystals after the water had moved through a number of magnetic fields. The former scarcity of crystallization nucleii in the water had been turned into an abundance of nucleation centers in the water. The reduction of the number of the substrate-bound crystals has been used as a quantitative measure of the magnetic effect. A mechanism is suggested assuming that resonance between the time sequence of the magnetic fields and the internal vibratory frequency of the water complexes results in the fracture of some of the complexes. Thereby, the formerly encased foreign particles are released and provide the nucleii for the formation of the disc-shaped crystals throughout the volume of the water Further studies are urged in view of the staggering potential benefits for many water uses, such as prevention of hard lime scale build-up, increased effectivity of chemical additions to water for softening, fertilizing, feeding, cleaning purposes.
Dynamics of the phase inversion process (1992)

Abstract An analysis of the dynamics of phase inversion based on mathematical modeling and in situ experimental observations is presented. Calculations based on ternary diffusion models illustrate the effects of casting film composition, evaporation time, and film thickness on the precipitation time and resulting polymer film profiles, which correlate with observed final morphologies. An experimental method based on the use of dark ground optics, interface visualization, and reflected light illumination is used for in situ monitoring of the mass transfer and phase separation dynamics during the quench step. Observations on the systems water—dimethylsulfoxide cellulose acetate and water—dioxane—cellulose acetate show regions in the films corresponding to gel formation and growth, instabilities associated with finger formation, and homogeneous ternary diffusion. Data for the kinetics of the diffusion and gel front motions show that both propagate as the square root of time with rates dependent on the bath—film compositions. Examples of interface structures characteristic of deep quenching and nucleated droplet growth are also shown. Semiquantitative analyses in terms of the ternary models developed earlier and a phenomenological model for diffusion in the growing gel are used to explain the trends seen. © 1992 John Wiley & Sons, Inc.
The Syk Inhibitor TAK-659 Prevents Splenomegaly and Tumor Development in a Murine Model of EBV-Associated Lymphoma (2016)

Abstract Epstein-Barr virus (EBV) is associated with the development of several cancers including Burkitt's Lymphoma, Hodgkin Lymphoma, Nasopharyngeal and Gastric Carcinomas. EBV-encoded Latent Membrane Protein 2A (LMP2A), a BCR mimic, is expressed in cancer cells and is essential for transformation, migration and inhibition of differentiation. LMP2A/λ-MYC double transgenic mice develop splenomegaly and lymphoma much faster than mice that express Myc only. LMP2A induces cancer phenotype by recruiting and activating BCR signaling components such as Lyn and Syk kinases to the SH2 motifs found on its N terminal cytoplasmic domain. In this study, we explored inhibition of Syk kinase activity with a novel Syk/FLT-3 inhibitor TAK-659, in lymphomas from these transgenic mice to assess SYK inhibition as a potential therapeutic strategy for EBV-associated malignancies. The cell lines developed from LMP2A/Myc transgenic mice derived lymphomas showed higher basal pSYK levels than Myc lymphoma cell lines. TAK-659 treatment resulted in early apoptosis within 8hrs in LMP2A/Myc lymphoma cells in comparison to 24 hrs in Myc lymphoma cells. In both pre-tumor and tumor transfer models in vivo, compared with placebo and Myc tumors, LMP2A/MYC mice treated with TAK-659 did not develop splenomegaly and tumor development was totally inhibited in these mice indicating SYK signaling is essential for tumor development in LMP2A/Myc mice. In addition, metastasis of tumor cells into BM was abrogated. TAK-659 killed tumor cells but not host cells in spleen and tumors. Taken together our data show that TAK-659, even in low nanomolar concentrations, inhibits pSYK and induces apoptosis in LMP2A/Myc tumor cells. It also inhibits splenomegaly and tumor development in our autochthonous and syngeneic tumor transfer models of EBV-associated lymphoma by targeting tumor cells while sparing non-tumor cells. Therefore, TAK-659 may provide an effective therapeutic option for the treatment of EBV-associated malignancies and should be explored further in clinical trials. Disclosures Kannan: Millennium Pharmaceuticals Inc., Cambridge, MA, USA, a wholly owned subsidiary of Takeda Pharmaceutical Company Limited: Employment. Huck:Takeda Pharmaceuticals International Co, Cambridge, MA: Employment. Yu:Takeda Pharmaceuticals International Co, Cambridge, MA: Employment. Zhang:Takeda Pharmaceuticals International Co, Cambridge, MA: Employment. Gordon:Northwestern University: Patents & Royalties: Patent for gold nanoparticles pending.
A New Strategy for Storage and Transportation of Sensitive High‐Energy Materials: Guest‐Dependent Energy and Sensitivity of 3D Metal–Organic‐Framework‐Based Energetic Compounds (2014)

Reaction of Co(II) with the nitrogen-rich ligand N,N-bis(1H-tetrazole-5-yl)-amine (H2bta) leads to a mixed-valence, 3D, porous, metal-organic framework (MOF)-based, energetic material with the nitrogen content of 51.78%, [Co9(bta)10(Hbta)2(H2O)10]n⋅(22 H2O)n (1). Compound 1 was thermohydrated to produce a new, stable, energetic material with the nitrogen content of 59.85% and heat of denotation of 4.537 kcal cm(-3), [Co9(bta)10(Hbta)2(H2O)10]n (2). Sensitivity tests show that 2 is more sensitivity to external stimuli than 1, reflecting guest-dependent energy and sensitivity of 3D, MOF-based, energetic materials. Less-sensitive 1 can be regarded as a more safe form for storage and transformation to sensitive 2.
Performance of a 50 Gbit/s optical time domain multiplexed system using a terahertz optical asymmetric demultiplexer (1994)

Bit error rate measurements were performed on a 50 Gbit/s optical time domain multiplexed system which utilized the newly developed terahertz optical asymmetric demultiplexer (TOAD) device as the front end of a receiver. Bit error rates of less than 10/sup /spl minus/9/ were measured when 800 fj control pulses were used to gate the demultiplexer. These measurements, which were made on a 50 Gbit/s peak line-rate train, also quantified the tolerance of the TOAD to signal-control pulse jitter.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Very Deep Convolutional Neural Networks for Raw Waveforms (2016)

Learning acoustic models directly from the raw waveform data with minimal processing is challenging. Current waveform-based models have generally used very few (~2) convolutional layers, which might be insufficient for building high-level discriminative features. In this work, we propose very deep convolutional neural networks (CNNs) that directly use time-domain waveforms as inputs. Our CNNs, with up to 34 weight layers, are efficient to optimize over very long sequences (e.g., vector of size 32000), necessary for processing acoustic waveforms. This is achieved through batch normalization, residual learning, and a careful design of down-sampling in the initial layers. Our networks are fully convolutional, without the use of fully connected layers and dropout, to maximize representation learning. We use a large receptive field in the first convolutional layer to mimic bandpass filters, but very small receptive fields subsequently to control the model capacity. We demonstrate the performance gains with the deeper models. Our evaluation shows that the CNN with 18 weight layers outperform the CNN with 3 weight layers by over 15% in absolute accuracy for an environmental sound recognition task and matches the performance of models using log-mel features.
Use of oregano extract and oregano essential oil as antioxidants in functional dairy beverage formulations (2011)

To increase health benefits, dairy beverages can be enriched with omega-3 fatty acids, although these fatty acids are susceptible to oxidation. The use of oregano extract (OE) and oregano essential oil (OEO) as antioxidants in dairy beverages enriched with 2 g/100 g linseed oil was studied. The OE contained 269 mg gallic acid equivalents per gram and was shown by the DPPH radical assay to have powerful antioxidant activity. During 10 days of storage under light or heat conditions, color, conjugated diene hydroperoxides, hexanal, propanal, and dissolved oxygen concentrations were evaluated in dairy beverages containing various concentrations of OE or OEO. It was found that OE was more efficient than OEO in preventing the formation of conjugated dienes, hexanal, and propanal as well as the depletion of oxygen induced by heat or light oxidation. The addition of OE or OEO did not affect dairy beverage physical stability during storage.
Coherent ultrasonic backscatter within a textured titanium alloy (2019)

The ultrasonic scattering from microtexture regions within a Ti-6Al-4V titanium alloy are analyzed for mode-converted shear wave interactions. Crystallographic orientation information gathered from electron backscatter diffraction (EBSD) measurements is used to guide the analysis, where critical orientations of the microtexture crystallites were identified and analyzed with respect to misorientation states, grain feature sizes, and shear wave propagation directions. The analysis suggests that large, aligned microtexture features within the titanium alloys can efficiently scatter and reflect the ultrasonic energy in a coherent manner when feature size, grain misorientation states, and grazing-incidence conditions are met for the shear-wave inspection fields. Analysis results are provided for a representative MTR feature which had generated a strong backscatter signal response. The results are expected to be important for NDE polycrystalline material inspections and characterization in titanium material aerospace applications.
Cranial Reshaping Using Methyl Methacrylate (2009)

Reconstruction of the facial skeleton and cranial vault has always posed difficult problems. To obtain a good result, various autologous, homologous, and heterologous grafts and biomaterials can be used. In this work, the authors present their experience in the use of methyl methacrylate (MMA) presenting a simple technique for application of the material that reduces the risk of complications. The authors also performed a review of the international bibliography relative to the use of MMA as an autologous bone substitute, analyzing the risks, complications, and results obtained.Between October 2003 and September 2007, the authors used MMA in procedures of cranial reshaping on 9 patients who underwent surgery to repair the damage caused by cranial-facial traumas and malformations.The technique of layered application of MMA made it possible to obtain excellent aesthetic and functional results in 8 patients, whereas in 1 case, the material had to be removed when the patient developed complications due to infection.Methyl methacrylate still remains the material of choice for cranioplasty on adult patients. The application of the material and sequenced layers makes it possible to reduce perioperative complications to the utmost, providing an excellent aesthetic and functional result.
TypA is involved in virulence, antimicrobial resistance and biofilm formation in Pseudomonas aeruginosa (2013)

Abstract Background Pseudomonas aeruginosa is an important opportunistic human pathogen and is extremely difficult to treat due to its high intrinsic and adaptive antibiotic resistance, ability to form biofilms in chronic infections and broad arsenal of virulence factors, which are finely regulated. TypA is a GTPase that has recently been identified to modulate virulence in enteric Gram-negative pathogens. Results Here, we demonstrate that mutation of typA in P. aeruginosa resulted in reduced virulence in phagocytic amoebae and human macrophage models of infection. In addition, the typA mutant was attenuated in rapid cell attachment to surfaces and biofilm formation, and exhibited reduced antibiotic resistance to ß-lactam, tetracycline and antimicrobial peptide antibiotics. Quantitative RT-PCR revealed the down-regulation, in a typA mutant, of important virulence-related genes such as those involved in regulation and assembly of the Type III secretion system, consistent with the observed phenotypes and role in virulence of P. aeruginosa . Conclusions These data suggest that TypA is a newly identified modulator of pathogenesis in P. aeruginosa and is involved in multiple virulence-related characteristics.
Feature Selection for Intrusion Detection Using Random Forest (2016)

An intrusion detection system collects and analyzes information from different areas within a computer or a network to identify possible security threats that include threats from both outside as well as inside of the organization. It deals with large amount of data, which contains various ir-relevant and redundant features and results in increased processing time and low detection rate. Therefore, feature selection should be treated as an indispensable pre-processing step to improve the overall system performance significantly while mining on huge datasets. In this context, in this paper, we focus on a two-step approach of feature selection based on Random Forest. The first step selects the features with higher variable importance score and guides the initialization of search process for the second step whose outputs the final feature subset for classification and in-terpretation. The effectiveness of this algorithm is demonstrated on KDD’99 intrusion detection datasets, which are based on DARPA 98 dataset, provides labeled data for researchers working in the field of intrusion detection. The important deficiency in the KDD’99 data set is the huge number of redundant records as observed earlier. Therefore, we have derived a data set RRE-KDD by eliminating redundant record from KDD’99 train and test dataset, so the classifiers and feature selection method will not be biased towards more frequent records. This RRE-KDD consists of both KDD99Train+ and KDD99Test+ dataset for training and testing purposes, respectively. The experimental results show that the Random Forest based proposed approach can select most im-portant and relevant features useful for classification, which, in turn, reduces not only the number of input features and time but also increases the classification accuracy.
Stochastic Insulator-to-Metal Phase Transition-Based True Random Number Generator (2017)

An oscillator-based true random number generator (TRNG) is experimentally demonstrated by exploiting inherently stochastic threshold switching in the insulator-to-metal transition (IMT) in vanadium dioxide. Through experimentation and modeling, we show that the origin of stochasticity arises from small perturbations in the nanoscale domain structure, which are then subsequently amplified through a positive feedback process. Within a 1T1R oscillator, the stochastic cycle-to-cycle variations in the IMT trigger voltage result in random timing jitter, which is harnessed for a TRNG. The randomness of the IMT TRNG output is validated using the NIST SP800-22 statistical test.
Necrosis as a prognostic factor in glioblastoma multiforme (1996)

The survival of patients with astrocytic neoplasms containing endothelial proliferation and no necrosis conforms best to the pattern expected for patients with GM rather than AA. This supports the classification of these tumors as GM in the revised World Health Organization grading system and as grade 4 astrocytomas in the St. Anne-Mayo grading system.
A neural network computation algorithm for discrete-time linear system state estimation (2003)

A neurocomputing approach is developed to solve the problem of state estimation for a discrete-time, linear dynamic system. Dynamic optimization techniques are used to develop the online adaptation laws for modifying the weights and biases of a deterministic Hopfield neural network, which in turn produces the estimate of the system state when the net reaches its stationary point. Simulation results show that the proposed approach performs similarly to the Kalman filter. Due to the parallel computational mode of the neural net, the proposed approach is more attractive for real-time implementation, from the computational point of view, than classical estimators.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
Pilot Study Evaluating Preference for 3‐mg Versus 6‐mg Subcutaneous Sumatriptan (2005)

Combining efficacy and tolerability endpoints may be clinically meaningful and reflective of real-world expectations. In some patients, a lower dose of sumatriptan injection may be beneficial.
Dual Mode Phased Array Antenna using Silicon RFICs based Integrated Beamforming Network (2021)

A dual mode (TM <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">11</sub> and TM <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">21</sub> ) phased array antenna at Ku-band is proposed using silicon RFICs based integrated beamforming network. The radiating element is a dual mode concentric ring patch and is capable of pattern reconfiguration between broadside and conical pattern. We can also excite both modes (TM <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">11</sub> and TM <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">21</sub> ) with proper amplitude and phase values so that we can suppress sidelobe/grating lobe present in the array performance. The array utilizes Anokiwave RFICs (AWMF-0117) which provides flat panel integration of the beamforming network with the antenna aperture. A suitable beamforming network for this array is being investigated. Array will be built and tested and additional results will be presented during the conference.
Stimuli-Responsive Polymers and their Potential Applications in Oil-Gas Industry (2015)

Polymers with properties well-controlled by minor environmental variations have been widely utilized in nanoscience, nanotechnology, and nanomedicine. Herein, the classification of stimuli-responsive polymers will be discussed and related to some possible applications in the oil-gas industry. Current studies of stimuli-responsive polymers in the oil-gas production are mainly focused on enhanced oil recovery (EOR) processes. Still, their potential applications in various aspects of the oil-gas industry from upstream, midstream, and downstream processes are found to be promising.
MiR-138 suppresses expression of hypoxia-inducible factor 1α (HIF-1α) in clear cell renal cell carcinoma 786-O cells. (2011)

miR-138 could inhibit the expression of HIF-1a and regulate the apoptosis and migration of ccRCC cells.
An Approach to Photonic Generation of High-Frequency Phase-Coded RF Pulses (2007)

A novel method to generate high-frequency phase-coded RF pulses using all-fiber components is proposed. The system consists of a mode-locked fiber laser (MLFL), a dispersive element, an unbalanced Mach-Zehnder interferometer (UMZI), an optical phase modulator (PM), and a photodetector (PD). The PM is incorporated in one arm of the UMZI. In the system, an ultrashort pulse generated by the MLFL is broadened and chirped after passing through the dispersive element, which is then sent to the UMZI, to get two time-delayed chirped pulses. By beating the time-delayed chirped pulses at the PD, an RF pulse with its frequency dependent on the time delay difference is obtained. The generated RF pulse can be phase coded if an encoding signal is applied to the PM. A theoretical model is presented which is verified by experiments. The generation of RF pulses with binary phase coding is also experimented
Validated HPLC method for the standardization of <i>Phyllanthus niruri</i> (herb and commercial extracts) using corilagin as a phytochemical marker (2009)

Abstract Phyllanthus niruri L., commonly known in Brazil as ‘quebra‐pedra’, has long been used in the treatment of diverse diseases and especially urolithiasis. The therapeutic effects of P. niruri are attributed to various compounds present in the plant, including the hydrolysable tannin corilagin. In the present study, high‐performance liquid chromatography (HPLC‐/PAD) profiles of leaves and commercial extracts of P. niruri were examined and three compounds, found to be present in all of the samples studied, were isolated by open column chromatography over C 18 silica gel followed by preparative HPLC. These compounds were identified by nuclear magnetic resonance as corilagin, rutin and ethyl 3,4,5‐trihydroxybenzoate. Corilagin, which has been proposed as a phytochemical marker for P. niruri , was employed as an external standard in the development and validation of a rapid and efficient qualitative and quantitative HPLC assay for the analyte. The method may be applied in the standardization of herbs and phytomedicines commercialized in Brazil as quebra‐pedra. Copyright © 2009 John Wiley & Sons, Ltd.