gebhart/patrepeval huggingface dataset:
Kiwifruit: our daily prescription for health (2012)

Kiwifruit are unequalled, compared with other commonly consumed fruit, for their nutrient density, health benefits, and consumer appeal. Research into their health benefits has focussed on the cultivars Actinidia deliciosa 'Hayward' (green kiwifruit) and Actinidia chinensis 'Hort 16A', ZESPRI(®) (gold kiwifruit). Compared with other commonly consumed fruit, both green and gold kiwifruit are exceptionally high in vitamins C, E, K, folate, carotenoids, potassium, fibre, and phytochemicals acting in synergy to achieve multiple health benefits. Kiwifruit, as part of a healthy diet, may increase high-density lipoprotein cholesterol, and decrease triglycerides, platelet aggregation, and elevated blood pressure. Consuming gold kiwifruit with iron-rich meals improves poor iron status, and green kiwifruit aids digestion and laxation. As a rich source of antioxidants, they may protect the body from endogenous oxidative damage. Kiwifruit may support immune function and reduce the incidence and severity of cold or flu-like illness in at-risk groups such as older adults and children. However, kiwifruit are allergenic, and although symptoms in most susceptible individuals are mild, severe reactions have been reported. While many research gaps remain, kiwifruit with their multiple health benefits have the potential to become part of our "daily prescription for health."
Estimation of cascade failure probability in electrical transmission networks by Subset Simulation (2010)

International audience
Tempering of cast nickel–aluminium bronze (1983)

AbstractAbstractMicrostructural changes associated with the tempering at 675°C of cast nickel–aluminium bronze, of nominal composition (wt-%) Cu–10Al–5Ni–5Fe, have been investigated using optical, electron optical, and microprobe analysis techniques. The tempering treatment resulted in the elimination of the non-equilibrium martensitic ('retained β') phase, precipitation with the α grains, and a coarsening of the as-cast structure. On heating to 675°C the martensite phase, which contained a high density of NiAl precipitates, reconstituted to form the high temperature bcc β phase and, after extended times at 675°C, this phase progressively decomposed into NiAl and α. The precipitates which formed in α grains were based on NiAl and had the B2 structure. These precipitates nucleated as laths either in the α matrix or on the pre-existing particles of Fe3Al; the two morphologies exhibited the Kurdjumov–Sachs and the Nishiyama–Wasserman orientation relationships, respectively, with α.
The onion technique (2000)

This paper describes the Onion technique, a special indexing structure for linear optimization queries. Linear optimization queries ask for top-N records subject to the maximization or minimization of linearly weighted sum of record attribute values. Such query appears in many applications employing linear models and is an effective way to summarize representative cases, such as the top-50 ranked colleges. The Onion indexing is based on a geometric property of convex hull, which guarantees that the optimal value can always be found at one or more of its vertices. The Onion indexing makes use of this property to construct convex hulls in layers with outer layers enclosing inner layers geometrically. A data record is indexed by its layer number or equivalently its depth in the layered convex hull. Queries with linear weightings issued at run time are evaluated from the outmost layer inwards. We show experimentally that the Onion indexing achieves orders of magnitude speedup against sequential linear scan when N is small compared to the cardinality of the set. The Onion technique also enables progressive retrieval, which processes and returns ranked results in a progressive manner. Furthermore, the proposed indexing can be extended into a hierarchical organization of data to accommodate both global and local queries.
Architectures and Bandwidth Allocation Schemes for Hybrid Wireless-Optical Networks (2014)

The combination of the most prestigious optical and wireless technologies for implementing a modern broadband integrated access network has been progressively gaining ground. By extending the network coverage in a cost-efficient way, hybrid wireless-optical networks are able to enclose a larger number of potential subscribers than standalone access architectures. Hence, they are capable of increasing revenue levels and facilitating commercial penetration to the telecom market. At the same time, hybrid wireless-optical networks pose an ambitious, alternative, and efficient solution to coping with new bandwidth-hungry user applications. Hybrid wireless-optical networks incorporate sophisticated modules, fabrics, and network entities to effectively provide adequate quality of service (QoS) provisioning. This survey endeavors to classify the main features of wireless-optical integration. We provide a comprehensive compilation of the latest architectures, integrated technologies, QoS features, and dynamic bandwidth allocation (DBA) schemes. In addition, new trends towards wireless-optical convergence are presented. Moreover, as the up-to-date hybrid network standards remain under development, since there is not yet an integrated standard for approving hybrid network access platforms, we accompany this survey with detailed challenges indicating potential avenues of future research.
A full mesh asynchronous transfer mode (ATM) satellite communications network (2002)

Effective operations in the tactical environment are becoming more dependent on the transfer of large quantities of multimedia information world-wide to both fixed and mobile platforms. Asynchronous transfer mode (ATM) technology offers great potential to meet this challenge. However it must adapt to the tactical environment which is characterized by operations over noisy narrowband wireless channels, changing network topologies, and limited bandwidth availability. Emerging bandwidth-on-demand (BoD) commercial satellite networking technology coupled with ATM can meet these challenges. In essence, providing seamless integration of the satellite network into the terrestrial fiber-optic based network. The resulting hybrid ATM network provides instantaneous, on demand connectivity anywhere in the world. We discuss an architecture providing satellite DAMA services to transport ATM traffic. Special considerations are taken to discuss meeting the quality of service (QoS) requirements for the associated ATM class of service requested. The areas discussed are an overall satellite architecture and ATM interface support which includes the SONET interface, forward error correction, ATM cell switching and call management functions.
Modulation of Cardiac Contractility by the Phopholamban/SERCA2a Regulatome (2012)

Heart disease remains the leading cause of death and disability in the Western world. Current therapies aim at treating the symptoms rather than the subcellular mechanisms, underlying the etiology and pathological remodeling in heart failure. A universal characteristic, contributing to the decreased contractile performance in human and experimental failing hearts, is impaired calcium sequestration into the sarcoplasmic reticulum (SR). SR calcium uptake is mediated by a Ca(2+)-ATPase (SERCA2), whose activity is reversibly regulated by phospholamban (PLN). Dephosphorylated PLN is an inhibitor of SERCA and phosphorylation of PLN relieves this inhibition. However, the initial simple view of a PLN/SERCA regulatory complex has been modified by our recent identification of SUMO, S100 and the histidine-rich Ca-binding protein as regulators of SERCA activity. In addition, PLN activity is regulated by 2 phosphoproteins, the inhibitor-1 of protein phosphatase 1 and the small heat shock protein 20, which affect the overall SERCA-mediated Ca-transport. This review will highlight the regulatory mechanisms of cardiac contractility by the multimeric SERCA/PLN-ensemble and the potential for new therapeutic avenues targeting this complex by using small molecules and gene transfer methods.
Experimental Study on a Self Standing Hybrid Riser System Throughout Tests on a Deep-Sea Model Basin (2005)

The present paper introduces a concept of a hybrid riser, Self Standing Hybrid Riser (SSHR), particularly in development for ultra deepwater around 3000 meters. Main problems faced in the initial definitions for design of such risers in the described scenario are discussed. Unique laboratory test with reduced model carried out in waves, current and riser top oscillation experiments in a very deepwater wave tank is shown. And, experimental results are shown and discussed, especially considering difficulties faced to carry out this experiment. Discussions are addressed in terms of vortex induced vibration (VIV) around buoyancy can, riser line pipe and flexible jumper.
On Real-Time Mean-and-Variance Normalization of Speech Recognition Features (2006)

This work aims at gaining an insight into the mean and variance normalization technique (MVN), which is commonly used to increase the robustness of speech recognition features. Several versions of MVN are empirically investigated, and the factors affecting their performance are considered. The reported experimental work with real-world speech data (Speecon) particularly focuses on the recursive updating of MVN parameters, paying attention to the involved algorithmical delay. First, we propose a decoupling of the look-ahead factor (which determines the delay) and the initial estimation of mean and variance, and show that the latter is a key factor for the recognition performance. Then, several kinds of initial estimations that make sense in different application environments are tested, and their performance is compared.
Evasion planning for autonomous vehicles at intersections (2012)

Autonomous intersection management (AIM) is a new intersection control protocol that exploits the capabilities of autonomous vehicles to control traffic at intersections in a way better than traffic signals and stop signs. A key assumption of this protocol is that vehicles can always follow their trajectories. But mechanical failures can occur in real life, causing vehicles to deviate from their trajectories. A previous approach for handling mechanical failure was to prevent vehicles from entering the intersection after the failure. However, this approach cannot prevent collisions among vehicles already in the intersection or too close to stop because (1) the lack of coordination among vehicles can cause collisions during the execution of evasive actions; and (2) the intersection may not have enough room for evasive actions. In this paper, we propose a preemptive approach that pre-computes evasion plans for several common types of mechanical failures before vehicles enter an intersection. This preemptive approach is necessary because there are situations in which vehicles cannot evade without pre-allocation of space for evasion. We present a modified AIM protocol and demonstrate the effectiveness of evasion plan execution on a miniature autonomous intersection testbed.
Strategies for consistent image partitioning (2004)

Graphic display technologies have traditionally targeted devices with midsize screens. However, devices with small and large screen sizes are gaining popularity, with users increasingly attempting to access complex images using small-screen devices. To display high-quality images irrespective of screen size, new methods of visualization become necessary. This article starts to address the difficult problem of finding acceptable methods to deal with screen-size variations. Instead of approaching the problem from a technology perspective, my techniques preserve graphic communication impact for specific visual analysis tasks without extensively modifying existing images or overly constraining authors of new images. Adapting visual content to retain graphic communication impact is essential to maximize the effectiveness of new devices.
Renin inhibitors containing new P1-P1' dipeptide mimetics with heterocycles in P1' (1992)

A series of renin inhibitors containing new P1-P1' dipeptide mimetics are presented. The P1-P1' mimetics were obtained from (4S,5S)-3-(tert-butoxycarbonyl)-4-(cyclohexylmethyl)-5-[(omega- mesyloxy)alkyl]-2,2-dimethyloxazolidines 5b, 9, and 11b by nucleophilic substitution of the mesylate groups with the sodium salts of mercapto- and hydroxyheterocycles. Removal of the protecting groups and stepwise acylations with amino acid derivatives provided renin inhibitors with a length of a tripeptide. Replacement of P2 histidine by other amino acids maintained or enhanced renin inhibitory potency. By alteration of P3 phenylalanine, compounds with IC50 values in the nanomolar range and stability against chymotrypsin were obtained. Finally, the effect of the C-terminal heterocycle on the renin inhibition was studied. Compound XVII was examined in vivo for its hypotensive effects. In salt-depleted cynomolgus monkeys, XVII inhibited plasma renin activity and lowered blood pressure after oral administration of a dose of 10 mg/kg.
Variable classification technique for software maintenance and application to the year 2000 problem (2002)

To support the maintenance of COBOL application systems, we have developed a variable classification technique that classifies program variables according to what domain entities they represent. Business application systems require frequent changes because the business rules associated with the domain entities are frequently changed. To modify the system, a source code containing variables of the same domain entity must be properly identified. Our variable classification technique supports the finding of all variables of a particular domain entity by analyzing programs. The paper describes the algorithm used for variable classification and its application to the year 2000 problem. The paper also evaluates the performance of the variable classification technique implemented in a commercial CASE tool.
Radioisotopes in Biology : A Practical Approach (2002)

1. Introduction 2. Radioisotope Use 3. Risk Assessments for the Use of Radioisotopes in Biology 4. Radioisotope Detection Using X-Ray Film 5. The Scintillation Counter 6. In vitro labelling of nucleic acids and proteins 7. Subcellular localization of biological molecules 8. Radioisotopes and immunoassay 9. Pharmacological Techniques 10. Summary of Legislation in Radiological Protection in the United Kingdom 11. Federal regulations on use of radionucleotides in the USA
Alienation and mobility (2016)

This paper will explore matters of alienation in personal mobility. It begins by outlining the present car system that dominates and has led to transport becoming an increasingly large issue terms of sustainability. The car system will then be located within the process of reification, an approach to alienation that identifies the car as a capitalist commodity pushed onto ordinary people. The paper will go on to explore the legacy that these developments have had on the twenty-first century landscape with cities made for cars and a countryside rendered car dependant. Possible alternatives to overcome the current car system will be identified, paying specific regard to schemes in Finland and Wales. The paper suggests that mobility should be construed as a common right and that there is a need to see past the current car system.
Distributed Misbehavior Detection in VANETs (2009)

In any vehicular adhoc network, there is always a possibility of incorrect messages being transmitted either due to faulty sensors and/or intentional malicious activities. Detecting and evicting sources of such misbehavior is an important problem. We observe that the performance of misbehavior detection schemes will depend on the application under consideration and the mobility dynamics of the detecting vehicle. Further, the underlying tradeoff in any such detection algorithm is the balance between False Positives and False Negatives; one would like to detect as many misbehaviors as possible, while at the same time ensuring that the genuine vehicles are not wrongly accused. In this work we propose and analyze (via simulations) the performance of a Misbehavior Detection Scheme (MDS) for Post Crash Notification (PCN) application. We observe that the performance of this proposed scheme is not very sensitive to the exact dynamics of the vehicle on small scales, so that slight error in estimating the dynamics of the detecting vehicle does not degrade the performance of the MDS.
Markerless real-time garment retexturing from monocular 3D reconstruction (2011)

We present a fusion of augmented reality (AR) and virtual try on (VTO) that incorporates sparse 3D point recovery by exploiting distance constraints based on 2D point correspondences between a deformed texture in monocular video and a reference texture which is derived from the start of the sequence by face detection aided segmentation. A hierarchical and multi-resolution surface reconstruction approach is proposed, employing thin-plate splines, cloth modeling, and patch tessellation. Our method attempts to accurately recover a rectangular surface from a deformed arbitrarily shaped texture. We also propose a hue-based method for segmenting garment cloth and printed texture. The methods are demonstrated in an AR framework for real-time visualization of a virtual garment worn in a real scene. Real-time AR cloth retexturing from monocular vision is a state-of-the-art field. Previous work lacks realism and accuracy, only recovering the 2D cloth layout and lacks robustness, requiring a special T-shirt color and simple texture along with lab hardware. Our approach alleviates these limitations. We design a practical approach which considers a typical consumer environment with a mid-range PC and webcam. Our results are convincing and photorealistic with robustness to arbitrary T-shirts, subjects, and backgrounds. Future work will focus on extending our global model and quantitative analysis.
Fetal haemoglobin induction in sickle cell disease (2017)

Fetal haemoglobin (HbF, α2γ2) induction has long been an area of investigation, as it is known to ameliorate the clinical complications of sickle cell disease (SCD). Progress in identifying novel HbF-inducing strategies has been stymied by limited understanding of gamma (γ)-globin regulation. Genome-wide association studies (GWAS) have identified variants in BCL11A and HBS1L-MYB that are associated with HbF levels. Functional studies have established the roles of BCL11A, MYB, and KLF1 in γ-globin regulation, but this information has not yielded new pharmacological agents. Several drugs are under investigation in clinical trials as HbF-inducing agents, but hydroxycarbamide remains the only widely used pharmacologic therapy for SCD. Autologous transplant of edited haematopoietic stem cells holds promise as a cure for SCD, either through HbF induction or correction of the causative mutation, but several technical and safety hurdles must be overcome before this therapy can be offered widely, and pharmacological therapies are still needed.
Sharp beveled tip hollow microneedle arrays fabricated by LIGA and 3D soft lithography with polyvinyl alcohol (2006)

This paper describes a fabrication process of hollow microneedle arrays with a sharp beveled tip for transdermal drug delivery. A master is fabricated through a double deep x-ray lithography process. First, a polymethylmethacrylate (PMMA) sheet is exposed to produce single PMMA parts with a sawtooth profile. The tip angle of each tooth determines the final tip angle of the microneedles. The PMMA parts are assembled and glued on a conductive substrate and then exposed through a second x-ray mask containing an array of hollow triangles as absorbing structures. A metal layer is then electrodeposited around the needles in order to form the future base of the array. A polyvinyl alcohol (PVA) solution is cast on top of the master to form a negative mold of the microneedle array after a low temperature curing and peel-off steps. A liquid PMMA solution is cast on top of the PVA negative mold and after the full PMMA polymerization the PVA is dissolved in water. This fabrication method can be performed in a non-clean room environment and requires little instrumentation. It is therefore compatible with a low-cost mass-fabrication scheme.
CRM - neue Perspektiven für das Marketing-Controlling (2002)

Month by month, Controlling - Zeitschrift für erfolgsorientierte Unternehmenssteuerung publishes peer-reviewed, applied research contributions for business management, accounting and reporting. Key elements of succesful corporate controlling are presented in an analytic, well-structured manner.
A 4-Gbps Uncompressed Wireless HD A/V Transceiver Chipset (2008)

Wireless transmission of uncompressed lossless HD video provides higher image quality with lower latency and cost than compressed-content transmission. however, it requires data rates of about 4 Gbps for 1080p resolution, exceeding the capabilities of existing wireless technologies. using the 60-GHZ band as detailed by the wirelessHD specification, SlBeam's chipset makes such data rates economically achievable.
A Survey of the Stability of Omeprazole Products from 13 Countries (1996)

The results of an independent survey of the stability of omeprazole solid dosage forms (20 mg) show that products available in many countries worldwide exhibit a very wide range of stability characteristics. Stability testing under the ICH accelerated test conditions (40°C/75% RH; 6 months) was performed on a total of 34 products obtained in 13 countries by independent sampling officers. The samples were visually examined for physical change and analyzed for their total content of impurities, remaining omeprazole, and the amount of omeprazole released in vitro. Twenty-seven of the products (79%) exhibited a change in one or more of the stability-indicating parameters during the 6-month study. These included 16 products that had more than 10% of decomposition products at 6 months and 10 other products that contained 2-10% of decomposition products at 6 months. In most samples, the formation of decomposition products was accompanied by a corresponding measurable decrease in the content of omeprazole. Of the eight samples containing less than 2% of decomposition products after 6 months storage, one showed a large reduction in the amount of omeprazole released in vitro. Another product which contained 1.2% decomposition products at 6 months released lower amounts of omeprazole in vitro at all time points than most other products. Only six products (18%) were considered to demonstrate good physical and chemical stability over the course of the study, viz. Losec Capsules (Astra, Sweden), Losec Capsules (Astra, Korea), Losec Capsules (Astra, Turkey), Miracid Capsules (Berlin Pharm. Ind. Co., Thailand), Mopral Capsules (Astra-Ifesa, Spain), and OMP Tablets (Chon Kun Dang Corp., Korea).
Practical theory of the multilayered transition radiation detector (1975)

The transition radiation detector for ultrarelativistic particles with a multifoil radiator is studied in the following aspects: x-ray spectrum, $\ensuremath{\gamma}$ dependence, interference effects, saturation at high $\ensuremath{\gamma}$, effects of irregularities, and multiple scattering. The analysis is simplified by reducing the various parameters to essentially three dimensionless quantities: a scaled Lorentz factor $\ensuremath{\Gamma}$, a scaled frequency $\ensuremath{\nu}$, and the ratio $\ensuremath{\tau}=\frac{\mathrm{foil} \mathrm{spacing}}{\mathrm{foil} \mathrm{thickness}}$. Large threshold effects due to interference are predicted which can be used to build a threshold detector or to measure the x-ray index of refraction of a material. Theoretical curves are given. Photon statistics, optimization of the detector, and computational method are discussed briefly.