gebhart/patrepeval huggingface dataset:
Inhibition of in Vivo Fertilization by Active Immunization of Male Hamsters against a 26-kDa Sperm Glycoprotein1 (1994)

We have identified a 26-kDa (P26h) epididymal hamster sperm glycoprotein with a species-specific affinity for zona pellucida glycoprotein. Two immunological procedures have been used to document the biological function of this sperm component; active immunization of males against P26h and inhibition of sperm-zona pellucida binding in vitro by anti-P26h antibodies. The immunized male hamsters produced circulating antibodies specific to P26h. Indirect immunofluorescence studies showed that these antibodies bind to the surface of the sperm covering the acrosome. These males were mated with superovulated females, and although spermatozoa were recovered from the genital tract, none of the 194 oocytes recovered were fertilized. In contrast, control males immunized with hamster albumin fertilized 97.4% of the oocytes. Unlike control spermatozoa, those recovered from the cauda epididymidis of males immunized with P26h were characterized by the presence of antibodies at the surface of the acrosome. To establish whether the inhibition of in vivo fertilization by active immunization was occurring at the level of sperm-zona pellucida interaction, a polyclonal antiserum against P26h was raised, and the IgG fraction was added to an in vitro sperm-zona pellucida assay. Compared to the preimmune serum, the IgG inhibited the binding of spermatozoa in a dose-dependent manner. The Fab fragments generated from these IgGs were almost as efficient in inhibiting the binding. These results are discussed with regard to a possible function of P26h in hamster gamete interaction.
Audited credential delegation - a user-centric identity management solution for computational grid environments (2010)

One major problem faced by end-users and administrators of computational grid environments arise in connection with the usability of the security mechanisms usually deployed in these environments, in particular identity management. Many of the existing computational grid environments use Public Key Infrastructure (PKI) and X.509 digital certificates as a corner stone for their security architectures. However, security solutions based on PKI have to be usable to be effective otherwise they will not provide the intended protection. This paper presents the Audited Credential Delegation (ACD), a user-centric security identity management solution that accommodates users and resource providers security requirements including authentication, authorisation and auditing security goals from the design level. The proposed architecture removes any association between users and digital certificates, which is the source of the grid usability problem, while addressing resource providers concerns with regards to accountability. A prototype of this architecture has been implemented in Java and Web Services technologies using the recommendations of the Open Web Application Security consortium (OWASP) for developing secure software. It is currently being tested on TeraGrid, NGS and DEISA grid infrastructures and a detailed usability study is underway.
A model-based complex background gesture recognition system (2002)

In this paper, a hand gesture recognition system is introduced to recognize the gestures of sequential digital number in a complex background. We present a method which uses the flexible models to describe the hand shapes and its variability. First, we present the hand shapes in the training set by the manually labeled points located on the boundary of the objects. Next, we align the all training shapes for examining the statistics of the coordinates of the model points over the training set. This flexible model can only fit the new hand examples which are similar to the shapes of the corresponding training set. From the extracted hand features, we can judge which state it belong to, and present the entire continuous gesture by a state sequence. In the experiments, we illustrate that the system can recognize the gestures of both single digital number and sequential digital number.
The COSCA PaaS platform (2012)

This talk will address our current research projects about cloud computing. The focus is on COSCA an OSGi-inspired PaaS system that allows applications to be composed from components. These can be individually updated and deployed similar to bundles in OSGi. COSCA further supports sockets for arbitrary communication. In the second part of the talk, we will address replication mechanisms and how they can be connected to COSCA. We will present multiple building blocks for fault-tolerant applications that were developed within COSCA's predecessor projects and are ready to be integrated.
A dodecahedral approach to immersive imaging and display (1997)

article Free Access Share on A dodecahedral approach to immersive imaging and display Author: David McCutchen Immersive Media Co., Portland, OR Immersive Media Co., Portland, ORView Profile Authors Info & Claims ACM SIGGRAPH Computer GraphicsVolume 31Issue 2May 1997 pp 35–37https://doi.org/10.1145/271283.271299Online:01 May 1997Publication History 3citation208DownloadsMetricsTotal Citations3Total Downloads208Last 12 Months2Last 6 weeks2 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my Alerts New Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Cytotoxicity of lignans from Lindera erytherocarpa makino (2002)

Three lignans were isolated from a methanol extract of Lindera erytherocarpa Makino (Lauraceae) are evaluated in vitro cytotoxicity using three cancer cell line assay. The compounds were identified as methyllinderone (1), linderone (2), and kanakugiol (3) by spectroscopic methods. Amongst the compounds, methyllinderone (1) showed significant cytotoxicity against mouse melanoma (B16-F10), human acetabulum fibrosarcoma (HT1080), and choronic myelogenous leukemia (K562) cancer cell lines with ED50 values of 2.2, 2.5, 8.3 μg/ml, respectively.
A low profile, low-RF band, small antenna for underground, in-situ sensing and wireless energy-efficient transmission (2014)

A key challenge to underground, in-situ soil sensing with wireless interface is the antenna size. Smaller operating frequency supports lower path losses but enhances the wavelength and hence the size of standard monpole (8.2 cm in height at 915MHz) or rectangular microstrip patch antenna (11.5 cm × 9.3 cm at 915 MHz), which is prohibitive for underground sensors. Lowering the frequency below 915MHz is not an option as it only further enhances the antenna size. To circumvent the size problem, a composite right-left handed (CRLH) microstrip patch antenna for wireless transmission at 915 MHz that doubles up as an underground, sensing element (external capacitor) has been designed and fabricated. The combined antenna/sensing CRLH patch integrates with the previously implemented on-board, multi-frequency dielectric based impedance sensor for soil moisture and nitrate determination and provides almost 93% reduction over the standard microstrip antenna size. As a proof of concept, the input impedance of the CRLH sensor, surrounded by the soil containing moisture and nitrate ions, is measured at multiple frequencies in the lab setting. It is shown that the change in moisture and nitrate can be successfully detected using the sensor. The small profile of the proposed antenna (3 cm × 2 cm), that is almost 93% smaller, makes it ideal for compact packaging.
Implications of methadone maintenance for theories of narcotic addiction (1988)

Clinical success in rehabilitation of heroin addicts with maintenance treatment requires stability of the blood level in a pharmacologically effective range (optimally, 150 to 600 ng/mL)—a phenomenon that emphasizes the central importance of narcotic receptor occupation. It is postulated that the high rate of relapse of addicts after detoxification from heroin use is due to persistent derangement of the endogenous ligand-narcotic receptor system and that methadone in an adequate daily dose compensates for this defect. Some patients with long histories of heroin use and subsequent rehabilitation on a maintenance program do well when the treatment is terminated. The majority, unfortunately, experience a return of symptoms after maintenance is stopped. The treatment, therefore, is corrective but not curative for severely addicted persons. A major challenge for future research is to identify the specific defect in receptor function and to repair it. Meanwhile, methadone maintenance provides a safe and effective way to normalize the function of otherwise intractable narcotic addicts. (<i>JAMA</i>1988;260:3025-3029)
Oblique-cut LiNbO_3 microchannel spatial light modulator (1982)

Significant improvements in the spatial resolution, framing speed, optical quality, and space-domain image-processing capabilities of the microchannel spatial light modulator have been realized by employing oblique-cut rather than z-cut LiNbO(3) crystals, high-strip-current (250-microA) microchannel plates, and an acceleration grid in the gap of the device. In particular, a prototype device employing a 330-microm-thick, optimum-cut (rotated 55 degrees from the z axis) LiNbO(3) crystal exhibited a framing rate in excess of 30 Hz with full modulation depth and a spatial resolution of ~1.9 cycles/mm at 50% contrast (~10 cycles/mm at 10% contrast). Additionally, four-level to two-level intensity image conversion, contrast reversal, contrast enhancement, edge enhancement, and the binary-level operations AND, NAND, OR, NOR, XOR, and NXOR have been demonstrated by operating the device in its space-domain image-processing mode.
The Neovessel Occlusion Efficacy of 15<sup>1</sup>‐Hydroxypurpurin‐7‐Lactone Dimethyl Ester Induced with Photodynamic Therapy (2010)

In this study, the photodynamic therapy (PDT) induced efficacy of a semi-synthesized analogue 15(1)-hydroxypurpurin-7-lactone dimethyl ester or G2, in terms of chick chorioallantoic membrane blood vessel occlusion was evaluated in reference to verteporfin. Early formulation studies showed that G2 prepared in a system of cremophor EL 2.5% and ethanol 2.5% in saline was biocompatible up to 20 microL volume of injection. Following injection, G2 accumulation peaked within the first minute and its extravasation from intra- to extra-vascular occurred somewhat slower as compared with verteporfin. In the PDT study, closure of capillaries and small neovessels was observed with 4 microg per embryo of G2 and a light dose of 20 J cm(-2) at a fluence rate of 40 mW cm(-2) filtered at 400-440 nm-a result that may be considered optimum for the treatment of age-related macular degeneration (AMD). Also, partial occlusion of the large vessels was observed using the same dose of G2 and light-an effect which is desirable for cancer treatment. From this study, we conclude that G2 has the potential to be developed as a therapeutic agent for photodynamic treatment for AMD and cancer.
RecoBERT: A Catalog Language Model for Text-Based Recommendations (2020)

Language models that utilize extensive selfsupervised pre-training from unlabeled text, have recently shown to significantly advance the state-of-the-art performance in a variety of language understanding tasks. However, it is yet unclear if and how these recent models can be harnessed for conducting text-based recommendations. In this work, we introduce RecoBERT, a BERT-based approach for learning catalog-specialized language models for text-based item recommendations. We suggest novel training and inference procedures for scoring similarities between pairs of items, that don't require item similarity labels. Both the training and the inference techniques were designed to utilize the unlabeled structure of textual catalogs, and minimize the discrepancy between them. By incorporating four scores during inference, RecoBERT can infer text-based item-to-item similarities more accurately than other techniques. In addition, we introduce a new language understanding task for wine recommendations using similarities based on professional wine reviews. As an additional contribution, we publish annotated recommendations dataset crafted by human wine experts. Finally, we evaluate Re-coBERT and compare it to various state-of-theart NLP models on wine and fashion recommendations tasks.
Nonvolumetric methods of detecting impaired intracranial compliance or reactivity (1979)

The authors have attempted to find a clinically reliable method of measuring intracranial pressure (ICP) compliance or reactivity that does not require volumetric manipulation. An analysis was undertaken of ICP, pulse widths and of the presence or absence of B waves, both experimentally in dogs and clinically in postoperative human patients. In both dogs and humans, ICP pulse width generally increased with increasing ICP and with increasing intracranial mass, and definitely increased with systolic arterial blood pressure. Nonetheless, ICP pulse width commonly failed to increase with increasing cerebral reactivity, and low ICP pulse width measurements were at times recorded in distinctly pathological situations. From the clinical study it was found that B waves were encountered more commonly in patients with increased ICP or increased ICP pulse width. However, the correlation between B waves alone or in combination with increased ICP or ICP pulse width and quantitative measurements of ICP reactivity was not significant. Mean reactivity and the range of reactivity measurements were almost identical in patient groups with and without B waves. For the time being the "ICP reserve test" remains the most accurate, the safest, and the most clinically useful method of quantitating ICP reserve.
Noninvasive Visualization and Analysis of Parafoveal Capillaries in Humans (2010)

Using motion cues to enhance vessel contrast is a powerful tool for visualizing the capillary network, in the absence of contrast agents. The authors demonstrate a tool to study the microcirculation of healthy subjects noninvasively.
High rate of multiple genital HPV infections detected by DNA hybridization (1992)

Cervical smears collected from 450 patients involved in a clinical follow-up of cervical human papillomaviruses (HPV) infections were screened for the presence of HPV 6b, 11, 16, and 18 DNA by both dot blot and southern blot hybridization methods. Using very high stringency hybridization assays, the four HPV types could be easily distinguished by dot blotting. After a preliminary clinical sorting, 42.9% of the samples were found to be HPV-positive. Among the samples infected by a single HPV, type 16 was the most frequent (25.4% of the positive samples) followed by 6b (19.7%), 11 (8.3%), and 18 (7.2%). Double or even multiple infections by the different HPV types were detected at a very high rate (39.4% of the positive samples).
Spherical tokamak generation and merging on UTST using ex‐vessel poloidal field coils only (2012)

Abstract We successfully generated two spherical tokamaks (ST) at two null points by using ex‐vessel poloidal field (PF) coils only and succeeded in merging them. This scheme is called a double null merging (DNM) scheme. First, two pairs of ex‐vessel PF coils generate two null points where the poloidal field is zero at the upper and lower regions inside the vacuum vessel. Then a poloidal flux swing generates two STs at two null points, because the distance to the wall along the magnetic field is long at the null points. Finally, the coil currents push two STs toward the mid‐plane and merge them into a single ST. Since a magnetic reconnection during merging transforms magnetic energy into thermal energy, this merged ST plasma is expected to have a high beta. It must be noted that the DNM scheme generates an ST without a center solenoid coil. The DNM scheme was demonstrated on the TS‐3/4 (Japan) and MAST (UKAEA). However, these devices have all PF coils inside the vacuum vessels, and the initial plasmas were generated around the PF coils, not the null points. Since internal coils are not feasible in a fusion reactor due to high neutron flux, it is important to demonstrate the DNM scheme by using ex‐vessel PF coils. © 2012 Wiley Periodicals, Inc. Electr Eng Jpn, 179(4): 18–24, 2012; Published online in Wiley Online Library ( wileyonlinelibrary.com ). DOI 10.1002/eej.21254
Interprocedural register allocation for lazy functional languages (1995)

Article Free Access Share on Interprocedural register allocation for lazy functional languages Author: Urban Boquist Department of Computing Science, Chalmers University of Technology, Göteborg, Sweden Department of Computing Science, Chalmers University of Technology, Göteborg, SwedenView Profile Authors Info & Claims FPCA '95: Proceedings of the seventh international conference on Functional programming languages and computer architectureOctober 1995 Pages 270–281https://doi.org/10.1145/224164.224215Online:01 October 1995Publication History 6citation236DownloadsMetricsTotal Citations6Total Downloads236Last 12 Months4Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
Pluggable authentication modules for Windows NT (1998)

To meet the challenge of integrating new methods and technologies into the Internet security framework, it is useful to hide low-level authentication mechanisms from application programmers, system administrators, and users, replacing them with abstractions at a higher level. The Pluggable Authentication Method approach popular in Linux, Solaris, and CDE offers one such abstraction. To implement
Detection of Equine Antibodies to<i>Babesia caballi</i>by Recombinant<i>B. caballi</i>Rhoptry-Associated Protein 1 in a Competitive-Inhibition Enzyme-Linked Immunosorbent Assay (1999)

A competitive-inhibition enzyme-linked immunosorbent assay (cELISA) was developed for detection of equine antibodies specific for Babesia caballi. The assay used recombinant B. caballi rhoptry-associated protein 1 (RAP-1) and monoclonal antibody (MAb) 79/17.18.5, which is reactive with a peptide epitope of a native 60-kDa B. caballi antigen. The gene encoding the recombinant antigen was sequenced, and database analysis revealed that the gene product is a rhoptry-associated protein. Cloning and expression of a truncated copy of the gene demonstrated that MAb 79/17.18.5 reacts with the C-terminal repeat region of the protein. The cELISA was used to evaluate 302 equine serum samples previously tested for antibodies to B. caballi by a standardized complement fixation test (CFT). The results of cELISA and CFT were 73% concordant. Seventy-two of the 77 serum samples with discordant results were CFT negative and cELISA positive. Further evaluation of the serum samples with discordant results by indirect immunofluorescence assay (IFA) demonstrated that at a serum dilution of 1:200, 48 of the CFT-negative and cELISA-positive serum samples contained antibodies reactive with B. caballi RAP-1. Four of five CFT-positive and cELISA-negative serum samples contained antibodies reactive with B. caballi when they were tested by IFA. These data indicate that following infection with B. caballi, horses consistently produce antibody to the RAP-1 epitope defined by MAb 79/17.18.5, and when used in the cELISA format, recombinant RAP-1 is a useful antigen for the serologic detection of anti-B. caballi antibodies.
Switching distributions and write reliability of perpendicular spin torque MRAM (2010)

We report data from 4-kbit spin torque MRAM arrays using tunnel junctions (TJs) with magnetization perpendicular to the wafer plane. We show for the first time the switching distribution of perpendicular spin torque junctions. The percentage switching voltage width, σ(V <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">c</inf> )/&#60;V <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">c</inf> > = 4.4%, is sufficient to yield a 64 Mb chip. Furthermore we report switching probability curves down to error probabilities of 5×10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">−9</sup> per pulse which do not show the anomalous switching seen in previous studies of in-plane magnetized bits.
Identification of the DNA-binding site for the phosphorylated VanR protein required for vancomycin resistance in Enterococcus faecium (1994)

The vancomycin resistance operon of Enterococcus faecium encodes a two-component regulatory system comprising VanS and VanR. In vitro experiments showed that about 5% of a labile phosphorylated VanR (P-VanR) was accumulated from ATP and a maltose-binding protein-VanS fusion protein (MBP-VanS). Alternatively, about an 8% abundance of P-VanR was produced with acetyl phosphate. In such incubations, gel shift experiments revealed that P-VanR selectively bound to a 254-bp DNA fragment that contains the vanH promoter for the vanH, vanA, and vanX structural genes. When VanS was added with a mole ratio for VanS:VanR of higher than 1:1, VanS competed with DNA for P-VanR and abolished the gel shift. P-VanR bound 500-fold more tightly to the vanH promoter region, with an estimated EC50 of 40 nM, than the unphosphorylated VanR. A second DNA fragment of 197 bp containing the proposed vanR promoter for the vanR and vanS regulatory genes also exhibited gel shift, but with much lower affinities. A mutant VanR(D53A) was shown to be incompetent for phosphorylation by phosphorylated MBP-VanS or by acetyl phosphate; however, it still bound DNA specifically, albeit with low affinity. DNase I footprinting by P-VanR revealed that a ca. 80-bp region was protected on the vanH promoter and a ca. 40-bp region was protected on the vanR promoter. The unphosphorylated VanR footprinted the same 80 bp on the vanH promoter, but only 20 bp on the vanR promoter.(ABSTRACT TRUNCATED AT 250 WORDS)
‘Fuzz Button’ interconnects at microwave and mm-wave frequencies (2000)

The important parameters which effect the performance of a connector at high data rates and rf frequencies are: crosstalk, signal propagation delay, capacitance, inductance, signal bandwidth, skin effect and phase shift amongst others. The characteristic impedance that is an important parameter of this type of connector is determined largely from the capacitance value and in some minor ways by the inductance value. This capacitance value, which is very low on a Fuzz Button connection, also affects directly the amount of crosstalk between adjacent pins. Capacitance and inductance also produce the phase shift between voltage and current and play an important role in the signal bandwidth. The higher the capacitance and the lower the value of inductance gives a lower characteristic impedance and vice versa. Characteristic impedance increases as the conductor cross section decreases.