gebhart/patrepeval huggingface dataset:
Characterization of isomeric compounds by gas and plasma chromatography (1979)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCharacterization of isomeric compounds by gas and plasma chromatographyD. F. HagenCite this: Anal. Chem. 1979, 51, 7, 870–874Publication Date (Print):June 1, 1979Publication History Published online1 May 2002Published inissue 1 June 1979https://pubs.acs.org/doi/10.1021/ac50043a022https://doi.org/10.1021/ac50043a022research-articleACS PublicationsRequest reuse permissionsArticle Views252Altmetric-Citations106LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Imported Lassa Fever in Germany: Surveillance and Management of Contact Persons (2003)

This study sought to assess the risk of secondary transmission after import of Lassa fever into Europe. A total of 232 persons exposed to a case of Lassa fever imported into Germany were identified. The level of exposure was determined for 157 persons (68%), and 149 (64%) were tested serologically. High-risk or close contact was reported by 30 (19%) of 157 persons. No symptomatic secondary infections were observed. However, Lassa virus-specific immunoglobulin G antibodies were detected in a serum sample obtained from a physician who examined the index patient on day 9 of illness. The physician received ribavirin prophylaxis and did not develop symptoms of Lassa fever. On the basis of these data, the contact was classified as having a probable secondary infection. The study indicates a low risk of transmission during the initial phase of symptomatic Lassa fever, even with high-risk exposures. The risk may increase with progression of disease and increasing virus load.
Hyperhomocyst(e)inemia as a Risk Factor for Occlusive Vascular Disease (1992)

The objective of this review is to provide an overview of intermittent fasting regimens, summarize the evidence on the health benefits of intermittent fasting, and discuss physiological mechanisms by which intermittent fasting might lead to improved ...Read More
Evolution of the virtual interface architecture (1998)

To provide a faster path between applications and the network, researchers have advocated removing the operating system kernel and its centralized networking stack from the critical path and creating a user level network interface. With these interfaces, designers can tailor the communication layers each process uses to the demands of that process. Consequently, applications can send and receive network packets without operating system intervention, which greatly decreases communication latency and increases network throughput. Unfortunately, the diversity of approaches and lack of consensus has stalled progress in refining research results into products-a prerequisite to the widespread adoption of these interfaces. Recently, however, Intel, Microsoft, and Compaq have introduced the Virtual Interface Architecture, an emerging standard for cluster or system area networks. Products based on the VIA have already surfaced, notably GigaNet's GNN1000 network interface. As more products appear, research into application level issues can proceed and the technology of user level network interfaces should mature. Several prototypes-among them Cornell University's U-Net2-have heavily influenced the VIA. We describe the architectural issues and design trade-offs at the core of these prototype designs.
Extracting age information from local spatially flexible patches (2008)

Motivated by the fact that age information can often be observed from local evidence on the human face, we contribute to the age estimation problem in two aspects. On the one hand, we present a new feature descriptor, called spatially flexible patch (SFP), which encodes the local appearance and position information simultaneously. SFP has the potential to alleviate the problem of insufficient samples owing to that SFPs similar in appearance yet slightly different in position can still provide similar confidence for age estimation. One the other hand, the SFP associated with age label is modeled with Gaussian Mixture Model, and then age estimation is conducted by maximizing the sum of likelihoods from all the SFPs associated with the hypothetic age. Experiments are conducted on the YAMAHA database with 8,000 face images and ages ranging from 0 to 93. Compared with the latest reported results, our new algorithm brings encouraging reduction in mean absolute error for age estimation.
Visualization of telomerase reverse transcriptase (hTERT) promoter activity using a trimodality fusion reporter construct. (2006)

hTERT promoter activity can be monitored by 1 radionuclide and 2 optical reporter systems using a single reporter construct. This in vitro study provides evidence that our multimodality reporter construct can be used to study the expression of a critical tumor growth gene in living subjects.
Encyclopedia of polymer science and engineering, Vol. 11: Photographic applications to polyesters, elastomeric (1987)

The contents of this book are: Photographic Applications; Photocrosslinking; Phthaloccyanine Polymers; Pipe; Plant Design; Plasma Polymerizaton; Plastic; Plasticizers; Plastics; Identification; Plastics, Processing; Polyacetals; Poly(alkylidene sulfides); Polyalkylidenes; Polyamides; Polyamides, Aromatic; Polyamides, Fibers; Polyamides, Plastics; Polyamides from Fatty Acids; Polyamides; Polyaminotriazoles; Polyampholtyes; Polyanhydrides; Poly(arylene sulfides); Polybenzimidazoles; Polybenzothiazoles; Polybenzoxazinones; Polybithiazoles; Polycarbonates; Polyelectrolytes; Polyesters, Polyesters, Aromatic; Polyesters, Containers; and Polyesters, Elastomeric.
Theoretical study of a thermoelectric-assisted vapor compression cycle for air-source heat pump applications (2014)

This paper proposes a thermoelectric-assisted vapor compression cycle (TVCC) for applications in air-source heat pump systems which could enhance the heating capacity of the system. Performances of TVCC are calculated and then compared with that of basic vapor compression cycle (BVCC). The simulation results show that when coefficients of performance (COPs) of the two cycles are almost equal, the TVCC under maximum COP condition of the thermoelectric modules still performs better than BVCC by 13.0% in heating capacity through selecting the appropriate intermediate temperature. In addition, the TVCC can also achieve an improvement of 16.4%–21.7% in both the heating COP and capacity when compared with the BVCC with an assistant electric heater that is provided with the equivalent power input of thermoelectric heat exchanger. Thus, the TVCC could be beneficial to the applications in small heat pumps if there is always need for auxiliary electric heat.
Microphthalmia-associated transcription factor as a regulator for melanocyte-specific transcription of the human tyrosinase gene. (1994)

Tyrosinase is a rate-limiting enzyme in melanin biosynthesis and is specifically expressed in differentiated melanocytes. We have identified the enhancer element in the 5'-flanking region of the human tyrosinase gene that is responsible for its pigment cell-specific transcription and have termed it tyrosinase distal element (TDE) (positions -1861 to -1842). Transient expression assays showed that TDE confers efficient expression of a firefly luciferase reporter gene linked to the tyrosinase gene promoter in MeWo pigmented melanoma cells but not in HeLa cells, which do not express tyrosinase. TDE was specifically bound by nuclear proteins of MeWo and HeLa cells, the binding properties of which were indistinguishable in gel mobility shift assays. TDE contains the CATGTG motif in its center, and mutation analysis indicates that the CA dinucleotides of this motif are crucial for protein binding and pigment cell-specific enhancer function. The CATGTG motif is consistent with the consensus sequence recognized by a large family of transcription factors with a basic helix-loop-helix structure, which prompted us to examine the possible involvement of a ubiquitous transcription factor, USF, and a novel factor, microphthalmia-associated transcription factor (MITF), recently cloned as the human homolog of the mouse microphthalmia (mi) gene product. The mi phenotype is associated with a mutant mi locus and characterized by small eyes and loss of melanin pigments. Both USF and MITF are predicted to contain a basic helix-loop-helix structure and a leucine zipper structure. We provide evidence that USF binds to TDE, whereas we were unable to detect the DNA-binding activity of MITF. Transient coexpression assays showed that MITF specifically transactivates the promoter activity of the tyrosinase gene through the CATGTG motif of TDE but not the promoter of the ubiquitously expressed heme oxygenase gene, while USF is able to activate both promoters. These results indicate that MITF is a cell-type-specific factor that is capable of activating transcription of the tyrosinase gene.
Hello, World: A Simple Application for the Field Programmable Port Extender (FPX) (2000)

The FPX provides simple and fast mechanisms to process cells or packets. By performing all computations in FPGA hardware, cells and packets can be processing at the full line speed of the card [currently 2.4 Gbits/sec]. A sample application, called 'Hello World' has been developed that illustrates how easily an application can be implemented on the FPX. This application uses the FPGA hardware to search for a string on a particular flow and selectively replace contents of the payload. The resulting circuit operates at 119 MHz on a Xilinx XCV 1000E-FG680-7, and occupies less than 1% of the available gates on the device.
Improved Method of Software Automation Testing Based on the Robotic Process Automation Technology (2019)

Nowadays the automation of repetitive and time consuming tasks for employees is becoming more and more popular. Automation of software testing has lots of benefits but it also has limited functions and strictly rely on the system under the test (SUT). One of the technologies that may be used to leverage its disadvantages is Robotic Process Automation (RPA). RPA is an approach to business workflow automation, in which the program emulates user actions within graphical user interface to achieve the desired result. In this paper the basic approaches for automation of software testing using RPA are investigated. This paper describes the proposed method for software test automation which allows to execute tests in a faster and more reliable way.
Petroleum Drilling and Production in the United States: Yield per Effort and Net Energy Analysis (1981)

For the past three decades the quantity of petroleum (both oil and oil plus gas) found per foot of drilling effort in the United States for any given year can be expressed as a secular decrease of about 2 percent per year combined with an inverse function of drilling effort for that year. Extrapolation of energy costs and gains from petroleum drilling and extraction indicates that drilling for domestic petroleum could cease to be a net source of energy by about 2004 at low drilling rates and by 2000 or sooner at high drilling rates, and that the net yield will be less at higher drilling rates.
Enhanced Expression, Native Purification, and Characterization of CCR5, a Principal HIV-1 Coreceptor (1999)

Seven-transmembrane segment, G protein-coupled receptors (GPCRs) play important roles in many biological processes in which pharmaceutical intervention may be useful. High level expression and native purification of GPCRs are important steps in the biochemical and structural characterization of these molecules. Here, we describe enhanced mammalian cell expression and purification of a codon-optimized variant of the chemokine receptor CCR5, a GPCR that plays a central role in the entry of the human immunodeficiency virus-1 (HIV-1) into immune cells. CCR5 could be solubilized in its native state as determined by its ability to be precipitated by 2D7, a conformation-dependent anti-CCR5 antibody, and by the HIV-1 gp120 envelope glycoprotein. The 2D7 antibody recognized immature and mature forms of CCR5 equally, whereas gp120 preferentially recognized the mature form, a result that underscores a role for posttranslational modification of CCR5 in its HIV-1 coreceptor function. The methods described herein contribute to the analysis of CCR5 and are likely to be applicable to many other GPCRs.
Efficiency and Safety of Mechanical Ventilation with a Heat and Moisture Exchanger Changed Only Once a Week (2000)

The cost of mechanical ventilation (MV) is high. Efforts to reduce this cost, as long as they are not detrimental for the patients, are needed. MV with heat and moisture exchangers (HME) changed every 48 h is safe, efficient, and cost-effective. Preliminary reports suggest that the life span of these filters may be prolonged. We determined prospectively whether a hygroscopic and hydrophobic HME (Hygrobac-Dar; Mallinckrodt) provided safe and efficient heating and humidification of the inspired gases when changed only once a week. Patients who were considered to require mechanical ventilation for more than 48 h were included in the study. HMEs were initially set for 7 d. Efficient airway heating and humidification were assessed by clinical parameters (number of tracheal suctionings and instillations required, peak airway pressures) and hygrometric measurements performed by psychrometry. Resistance was measured from Day 0 to Day 7. Bacterial colonization of circuits and HMEs was studied. A total of 377 days of mechanical ventilation with 60 HMEs was studied. Clinical parameters and hygrometric measurements did not change between Day 0 and Day 7. Mean absolute humidity was 30.3 +/- 1.3 mg H(2)O/L on Day 0 and 30.8 +/- 1.5 mg H(2)O/L on Day 7 (p = 0.7). Endotracheal tube occlusion never occurred. Three HMEs were replaced prematurely because of insufficient absolute humidity. This rare event occurred only in patients with COPD and after the third day of use. In addition, the absolute humidity delivered by the HMEs was significantly lower in patients with COPD than in the rest of the population. Resistance did not change from Day 0 to Day 7 (2.4 +/- 0.3 versus 2.7 +/- 0.3 cm H(2)O/L/s; p = 0.4). Bacterial samples of both circuits and ventilator sides of HMEs were sterile in most cases. We conclude that mechanical ventilation can be safely conducted in non-COPD patients using an HME changed only once a week, leading to substantial cost savings (about $110,000 per year if these findings were applied to the university-affiliated hospitals in Paris).
幻境中的莫扎特——民族音乐学、科技和描述中存在的问题 (2000)

在科幻小说中,时空穿梭可能是最常用到的情节。在电子旁克式的科幻小说《幻境中的莫扎特》(斯特灵和施奈尔,Stering and Shiner,1985)中,作者将改变历史的构思进行了带有讽刺意味的后现代式的变形。在这部采用调侃的方式来描写欧洲强势文化与美国弱势文化的冲突的故事里,时间并非是按过去、现在和将来连接的。其延展的可能性
Towards the reconstruction of central nervous system white matter using neural precursor cells (2001)

Epidermal growth factor-responsive neural precursor cells were used as donor cells for transplantation into wild-type and myelin-deficient shiverer (shi) mice. The cells engrafted robustly within the CNS following intracerebroventricular and cisternal transplantation in neonatal mice. The cells adopted glial phenotypes, and some functioned as oligodendrocytes, producing myelin basic protein and morphologically normal internodal myelin sheaths. When individual shi mice received two transplants (on post-natal days 1 and 3), donor-derived cells disseminated widely and expressed myelin basic protein in central white matter tracts throughout the brain.
Role of Integrins in Cancer: Survey of Expression Patterns (1999)

Tumor cells are characterized by uncontrolled growth, invasion to surrounding tissues, and metastatic spread to distant sites. Mortality from cancer is often due to metastasis since surgical removal of tumors can enhance and prolong survival. The integrins constitute a family of transmembrane receptor proteins composed of heterodimeric complexes of noncovalently linked alpha and beta chains. Integrins function in cell-to-cell and cell-to-extracellular matrix (ECM) adhesive interactions and transduce signals from the ECM to the cell interior and vice versa. Hence, the integrins mediate the ECM influence on cell growth and differentiation. Since these properties implicate integrin involvement in cell migration, invasion, intra- and extra-vasation, and platelet interaction, a role for integrins in tumor growth and metastasis is obvious. These findings are underpinned by observations that the integrins are linked to the actin cytoskeleton involving talin, vinculin, and alpha-actinin as intermediaries. Such cytoskeletal changes can be manifested by rounded cell morphology, which is often coincident with tumor transformation via decreased or increased integrin expression patterns. For the various types of cancers, different changes in integrin expression are further associated with tumor growth and metastasis. Tumor progression leading to metastasis appears to involve equipping cancer cells with the appropriate adhesive (integrin) phenotype for interaction with the ECM. Therapies directed at influencing integrin cell expression and function are presently being explored for inhibition of tumor growth, metastasis, and angiogenesis. Such therapeutic strategies include anti-integrin monoclonal antibodies, peptidic inhibitors (cyclic and linear), calcium-binding protein antagonists, proline analogs, apoptosis promotors, and antisense oligonucleotides. Moreover, platelet aggregation induced by tumor cells, which facilitates metastatic spread, can be inhibited by the disintegrins, a family of viper venom-like peptides. Therefore, adhesion molecules from the integrin family and components of angiogenesis might be useful as tumor progression markers for prognostic and for diagnostic purposes. Development of integrin cell expression profiles for individual tumors may have further potential in identifying a cell surface signature for a specific tumor type and/or stage. Thus, recent advances in elucidating the structure, function, ECM binding, and signaling pathways of the integrins have led to new and exciting modalities for cancer therapeutics and diagnoses.
High Power Factor Operation of a Three-Phase Rectifier for an Adjustable-Speed Drive (2008)

This paper presents a novel approach to improve the power factor (PF) and reduce the harmonics generated by an adjustable-speed drive (ASD). A high-frequency (HF) current injection technique is used to improve the PF and harmonic performance. The HF current at the same switching frequency (33 kHz) is injected into the input of a front-end rectifier from the output of an HF inverter. The main feature of the circuit is that it does not require any additional active devices for current injection. The inverter driving the induction motor is operated using a sinusoidal pulsewidth-modulation technique. The circuit simulation and experimental prototype results are presented for 67-hp (50 kW) and 3-hp three-phase induction motors, respectively.
Nucleoporin NUP153 Phenylalanine-Glycine Motifs Engage a Common Binding Pocket within the HIV-1 Capsid Protein to Mediate Lentiviral Infectivity (2013)

Lentiviruses can infect non-dividing cells, and various cellular transport proteins provide crucial functions for lentiviral nuclear entry and integration. We previously showed that the viral capsid (CA) protein mediated the dependency on cellular nucleoporin (NUP) 153 during HIV-1 infection, and now demonstrate a direct interaction between the CA N-terminal domain and the phenylalanine-glycine (FG)-repeat enriched NUP153 C-terminal domain (NUP153(C)). NUP153(C) fused to the effector domains of the rhesus Trim5α restriction factor (Trim-NUP153(C)) potently restricted HIV-1, providing an intracellular readout for the NUP153(C)-CA interaction during retroviral infection. Primate lentiviruses and equine infectious anemia virus (EIAV) bound NUP153(C) under these conditions, results that correlated with direct binding between purified proteins in vitro. These binding phenotypes moreover correlated with the requirement for endogenous NUP153 protein during virus infection. Mutagenesis experiments concordantly identified NUP153(C) and CA residues important for binding and lentiviral infectivity. Different FG motifs within NUP153(C) mediated binding to HIV-1 versus EIAV capsids. HIV-1 CA binding mapped to residues that line the common alpha helix 3/4 hydrophobic pocket that also mediates binding to the small molecule PF-3450074 (PF74) inhibitor and cleavage and polyadenylation specific factor 6 (CPSF6) protein, with Asn57 (Asp58 in EIAV) playing a particularly important role. PF74 and CPSF6 accordingly each competed with NUP153(C) for binding to the HIV-1 CA pocket, and significantly higher concentrations of PF74 were needed to inhibit HIV-1 infection in the face of Trim-NUP153(C) expression or NUP153 knockdown. Correlation between CA mutant viral cell cycle and NUP153 dependencies moreover indicates that the NUP153(C)-CA interaction underlies the ability of HIV-1 to infect non-dividing cells. Our results highlight similar mechanisms of binding for disparate host factors to the same region of HIV-1 CA during viral ingress. We conclude that a subset of lentiviral CA proteins directly engage FG-motifs present on NUP153 to affect viral nuclear import.
Vacant-Site Octahedral Tilings onSrTiO3(001), the(13×13)R33.7°Surface, and Related Structures (2011)

The structure of the SrTiO(3) (001) (sqrt[13]×sqrt[13])R33.7° surface reconstruction has been determined using transmission electron diffraction combined with direct methods and density functional theory. It has a TiO(2)-rich surface with a 2D tiling of edge or corner-sharing TiO(5)□ octahedra. Additionally, different arrangements of these octahedral units at the surface, dictated by local bond-valence sums, form 2D networks that can account for many ordered surface reconstructions as well as disordered glasslike structures consistent with the multitude of structures observed experimentally, and potentially other materials and interfaces.
Scalable Attribute-Value Extraction from Semi-structured Text (2009)

This paper describes a general methodology for extracting attribute-value pairs from Web pages. It consists of two phases: candidate generation, in which syntactically likely attribute-value pairs are annotated; and candidate filtering, in which semantically improbable annotations are removed. We describe three types of candidate generators and two types of candidate filters, all of which are designed to be massively parallelizable. Our methods can handle 1 billion Web pages in less than 6 hours with 1,000 machines. The best generator and filter combination achieves 70% F-measure compared to a hand-annotated corpus.