gebhart/patrepeval huggingface dataset:
A probabilistic model for estimating driver behaviors and vehicle trajectories in traffic environments (2010)

This paper presents a filter that is able to simultaneously estimate the behaviors of traffic participants and anticipate their future trajectories. This is achieved by recognizing the type of situation derived from the local situational context, which subsumes all information relevant for the drivers decision making. By explicitly taking into account the interactions between vehicles, it achieves a comprehensive situational understanding, inevitable for autonomous vehicles and driver assistance systems. This provides the necessary information for safe behavior decision making or motion planning. The filter is modeled as a Dynamic Bayesian Network. The factored state space, modeling the causal dependencies, allows to describe the models in a compact fashion and reduces the computational complexity of the inference process. The filter is evaluated in the context of a highway scenario, showing a good performance even with very noisy measurements. The presented framework is intended to be used in traffic environments but can be easily transferred to other robotic domains.
Development of a Web-Based Intelligent Agent for the Fashion Selection and Purchasing Process via Electronic Commerce (1998)

This paper describes a conceptual, web-based, intelligent fashion agent designed to assist the consumer in the fashion selection and purchasing process via electronic commerce. The agent is a hybrid system combining expert system software and web technology. Fashion selection is a complex process involving multiple objectives, criteria and alternatives that can be resolved by an expert system. Based on the development of the prototype Web-Based Interactive Fashion Expert (WIFE) system, problems with the conceptual system are identified and solutions proposed where applicable.
Concise and Efficient Synthesis of 1H-Pyrazoles: Reaction of [Hydroxy(tosyloxy)iodo]benzene with Ethyl 2,3-Dioxobutanoate-2-arylhydrazones (1991)

Abstract Ethyl 2,3-dioxobutanoate-2-arylhydrazones 1 on treatment with [hydroxy(tosyloxy)iodo]benzene 2 at reflux temperature and followed by heating in the presence of N-ethyldiisopropylamine afforded the cyclized ethyl 1-aryl-4-hydroxy-1H-3-pyrazolecarboxylates 4 in good yield.
Microfluid Mechanics: Principles and Modeling (2005)

PET and SPECT are important investigations to localize the epileptic focus in temporal lobe and nonlesional extratemporal epilepsies. Postprocessing for both modalities is important to increase diagnostic value.
Automatic dialect identification of extemporaneous conversational, Latin American Spanish speech (2002)

A dialect identification technique is described that takes as input extemporaneous, conversational speech spoken in Latin American Spanish and produces as output a hypothesis of the dialect. The system has been trained to recognize Cuban and Peruvian dialects of Spanish, but could be extended easily to other dialects (and languages) as well. Building on our experience in automatic language identification, the dialect-ID system uses an English phone recognizer trained on the TIMIT corpus to tokenize training speech spoken in each Spanish dialect. Phonotactic language models generated from this tokenized training speech are used during testing to compute dialect likelihoods for each unknown message. This system has an error rate of 16% on the Cuban/Peruvian two-alternative forced-choice test. We introduce the new "Miami" Latin American Spanish speech corpus that is capable of supporting our research efforts into the future.
Spectroscopic Methods (1971)

Physical methods have greatly influenced carotenoid research. Prior to the systematic application of these methods polyene chemistry was a rather troublesome field in comparison with the situation today.
Expression of killer cell inhibitory receptors on human uterine natural killer cells (1997)

The establishment of the human placenta in early pregnancy is characterized by the presence of large numbers of natural killer (NK) cells within the maternal decidua in close proximity to the fetally-derived invading extravillous trophoblast which expresses at least two HLA class I molecules, HLA-G and HLA-C. These NK cells have an unusual phenotype, CD56(bright) CD16, distinguishing them from adult peripheral blood NK cells. They may control key events in trophoblast migration and therefore placentation. Human NK cells in peripheral blood express receptors for polymorphic HLA class I molecules. This family of receptors, known as killer cell inhibitory receptors (KIR), are expressed on overlapping subsets of NK cells to give an NK cell repertoire which differs between individuals. Using a panel of monoclonal antibodies to several members of the KIR family and analysis by flow cytometry, we have found that KIR are expressed by decidual NK cells. There is variation in both the percentage of cells expressing a particular receptor and the density of receptor expression between decidual NK cells from different individuals. Comparison of NK cells from decidua and peripheral blood of the same individual showed that NK cells from these two different locations express different repertoires of KIR. Receptors are present in individuals who do not possess the relevant class I ligand, raising the possibility that these NK receptors may be involved in recognition of the allogeneic fetus by the mother at the implantation site.
RNA Sequences Involved in Transcriptional Termination of Respiratory Syncytial Virus (2001)

RNA signals at the ends of the genes of respiratory syncytial (RS) virus direct polyadenylation and termination of viral transcription. These gene ends contain two conserved regions, a pentanucleotide and a tract of uridylate (U) residues, separated by an A/U-rich central region that is less well conserved. The U tract is thought to be the template for polyadenylation of viral mRNAs by reiterative transcription. The cis-acting requirements for termination were investigated by mutagenesis of the matrix (M) gene end (3'-UCAAUUAUUUUUU-5') in a dicistronic RNA replicon. Termination efficiencies were quantitated by intracellular metabolic labeling of monocistronic mRNAs and the dicistronic readthrough RNAs that result when termination fails to occur. All three regions of the gene end were necessary for termination. Mutation of each of the first 8 nucleotides of the M gene end to all other nucleotides showed that nucleotides 2 to 6 were important for termination and intolerant of change, whereas nucleotides 1 and 7 were tolerant of change. At position 8, A or U allowed termination, but G or C did not. Both the length and the position of the U tract were important for termination. U residues at positions 9 to 12 were necessary, while additional U residues at position 8, and especially position 13, enhanced termination efficiency. Altering the length of the central region abolished termination, suggesting that the position of the U tract with respect to the 3'-UCAAU-5' sequence was critical. The termination efficiencies of each of the 10 genes of RS virus are different. Since transcription is obligatorily sequential and termination of each gene is required for transcription of the next gene downstream, these differences may contribute to gene regulation. In agreement with our data, the naturally occurring gene ends of RS virus that terminate inefficiently have short U tracts or other sequence features that correlated with decreased termination when similar mutations were analyzed in RNA replicons.
Influence of atrioventricular nodal reentrant tachycardia ablation on right to left inter-atrial conduction. (2005)

RF ablation of AVNRT results in prolongation of IACT. The degree of prolongation is associated with the duration and number of RF ablations given. The relationship between this conduction delay and late arrhythmogenesis need to be evaluated.
Cutting Edge: Critical Role of Inducible Costimulator in Germinal Center Reactions (2001)

Inducible costimulator (ICOS) is a new member of the CD28/CTLA-4 family that is expressed on activated and germinal center (GC) T cells. Recently, we reported that ICOS-deficient mice exhibited profound defects in T cell activation and effector function. Ab responses in a T-dependent primary reaction and in a murine asthma model were also diminished. In the current study, we investigate the mechanism by which ICOS regulates humoral immunity and examine B cell GC reactions in the absence of ICOS. We found that ICOS(-/-) mice, when immunized with SRBC, had smaller GCs. Furthermore, IgG1 class switching in the GCs was impaired. Remarkably, GC formation in response to a secondary recall challenge was completely absent in ICOS knockout mice. These data establish a critical role of ICOS in regulation of humoral immunity.
An adaptive query execution system for data integration (1999)

Query processing in data integration occurs over network-bound, autonomous data sources. This requires extensions to traditional optimization and execution techniques for three reasons: there is an absence of quality statistics about the data, data transfer rates are unpredictable and bursty, and slow or unavailable data sources can often be replaced by overlapping or mirrored sources. This paper presents the Tukwila data integration system, designed to support adaptivity at its core using a two-pronged approach. Interleaved planning and execution with partial optimization allows Tukwila to quickly recover from decisions based on inaccurate estimates. During execution, Tukwila uses adaptive query operators such as the double pipelined hash join, which produces answers quickly, and the dynamic collector, which robustly and efficiently computes unions across overlapping data sources. We demonstrate that the Tukwila architecture extends previous innovations in adaptive execution (such as query scrambling, mid-execution re-optimization, and choose nodes), and we present experimental evidence that our techniques result in behavior desirable for a data integration system.
The serological classification of Neisseria gonorrhoeae. I. Isolation of the outer membrane complex responsible for serotypic specificity. (1976)

Neisseria gonorrhoeae has been subdivided into several classes of serological distinct groups. The serotyping system is based upon the antigenic specificity of a protein serotype antigen. This protein is the major polypeptide of the outer membrane of the gonococcus and accounts for over 60% of that membrane's total protein. The serotype antigen complex was isolated by mild extraction of intact organisms in 200 mM lithium acetate buffer, pH 6.0 with 10 mM EDTA for 2 h at 45 degrees C. The extract was fractionated on Sepharose 6B and partially purified by precipitation at pH 4.2 by addition of 10% (vol/vol) acetic acid. Each serotype antigen has a unique subunit molecular size as determined by sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE). Preliminary typing of a gonococcal strain may be performed by comparative SDA-PAGE. To date, 16 different serotypes, representing a diverse distribution, have been isolated.
Five-Year Follow-Up After Clinical Islet Transplantation (2005)

Islet transplantation can restore endogenous beta-cell function to subjects with type 1 diabetes. Sixty-five patients received an islet transplant in Edmonton as of 1 November 2004. Their mean age was 42.9 +/- 1.2 years, their mean duration of diabetes was 27.1 +/- 1.3 years, and 57% were women. The main indication was problematic hypoglycemia. Forty-four patients completed the islet transplant as defined by insulin independence, and three further patients received >16,000 islet equivalents (IE)/kg but remained on insulin and are deemed complete. Those who became insulin independent received a total of 799,912 +/- 30,220 IE (11,910 +/- 469 IE/kg). Five subjects became insulin independent after one transplant. Fifty-two patients had two transplants, and 11 subjects had three transplants. In the completed patients, 5-year follow-up reveals that the majority ( approximately 80%) have C-peptide present post-islet transplant, but only a minority ( approximately 10%) maintain insulin independence. The median duration of insulin independence was 15 months (interquartile range 6.2-25.5). The HbA(1c) (A1C) level was well controlled in those off insulin (6.4% [6.1-6.7]) and in those back on insulin but C-peptide positive (6.7% [5.9-7.5]) and higher in those who lost all graft function (9.0% [6.7-9.3]) (P < 0.05). Those who resumed insulin therapy did not appear more insulin resistant compared with those off insulin and required half their pretransplant daily dose of insulin but had a lower increment of C-peptide to a standard meal challenge (0.44 +/- 0.06 vs. 0.76 +/- 0.06 nmol/l, P < 0.001). The Hypoglycemic score and lability index both improved significantly posttransplant. In the 128 procedures performed, bleeding occurred in 15 and branch portal vein thrombosis in 5 subjects. Complications of immunosuppressive therapy included mouth ulcers, diarrhea, anemia, and ovarian cysts. Of the 47 completed patients, 4 required retinal laser photocoagulation or vitrectomy and 5 patients with microalbuminuria developed macroproteinuria. The need for multiple antihypertensive medications increased from 6% pretransplant to 42% posttransplant, while the use of statin therapy increased from 23 to 83% posttransplant. There was no change in the neurothesiometer scores pre- versus posttransplant. In conclusion, islet transplantation can relieve glucose instability and problems with hypoglycemia. C-peptide secretion was maintained in the majority of subjects for up to 5 years, although most reverted to using some insulin. The results, though promising, still point to the need for further progress in the availability of transplantable islets, improving islet engraftment, preserving islet function, and reducing toxic immunosuppression.
Proteolytic enzymes from recombinant Streptomyces lividans TK24 (1989)

Different proteases from the culture fluids of recombinant Streptomyces lividans strains were isolated. Several individual proteases were separated and characterized. A chymotrypsin-chylike activity (CLA) was identified that specifically degrades a fusion protein between the alpha-amylase inhibitor from S. tendae (Tendamistat, HOE467) and proinsulin from the monkey Macaca fascicularis. The effective chemical inhibition of the degrading enzyme is demonstrated.
Improved survival of gastric cancer with tumour Epstein–Barr virus positivity: an international pooled analysis (2013)

Our findings suggest that tumour EBV positivity is an additional prognostic indicator in gastric cancer. Further studies are warranted to identify the mechanisms underlying this protective association.
Human neutrophil lipocalin is a unique marker of neutrophil inflammation in ulcerative colitis and proctitis (2002)

We conclude that the increased release of HNL and MPO in colorectal perfusion fluids indicates neutrophil involvement in the local inflammatory process, and suggest that HNL may serve as a specific marker of intestinal neutrophil activation in UC. GM-CSF, and to some extent IL-8, may play a role in neutrophil accumulation and priming in this disease.
Combining infliximab and methotrexate in fistulizing Crohn's disease resistant or intolerant to azathioprine (2004)

A combination of infliximab with long-term methotrexate may be a promising concept in fistulizing Crohn's disease. Our data indicate the need for larger controlled trials.
La organización del Prácticum: una inversión con importantes rendimientos (2001)

La organizacion del Practicum ha pasado en los ultimos 15 anos por diversas situaciones y circunstancias. Un analisis en el tiempo requeriria analizar la situacion tomando como referencia la implementacion de los nuevos Planes de Estudios desde el curso 1993/94 y la posterior puesta en marcha de Practicum como asignatura Troncal. Este analisis lo vamos a realizar desde la perspectiva del Departamento de Didactica y Organizacion Escolar y desde las estructuras organizativas y experiencias que desde el se han realizado.
Blastocystis hominis revisited (1996)

Blastocystis hominis is a unicellular organism found commonly in the intestinal tract of humans and many other animals. Very little is known of the basic biology of the organism, and controversy surrounds its taxonomy and pathogenicity. There morphological forms (vacuolar, granular, and ameboid) have been recognized, but recent studies have revealed several additional forms (cyst, avacuolar, and multivacuolar). The biochemistry of the organism has not been studied to any extent, and organelles and structures of unknown function and composition are present in the cells. Several life cycles have been proposed but not experimentally validated. The form used for transmission has not been defined. Infections with the organism are worldwide and appear in both immunocompetent and immunodeficient individuals. Symptoms generally attributed to B. hominis infection are nonspecific, and the need for treatment is debated. If treatment appears warranted, metronidazole is suggested as the drug of choice, although failures of this drug in eradicating the organism have been reported. Infection is diagnosed by light microscopic examination of stained smears or wet mounts of fecal material. Most laboratories identify B. hominis by observing the vacuolar form, although morphological studies indicate that other forms, such as the cyst form and multivacuolar form, also should be sought for diagnosis.
Covalent Bonding of Alkene and Alkyne Reagents to Graphitic Carbon Surfaces (2005)

Various aromatic and aliphatic alkynes and one alkene were covalently bonded to sp2-hybridized carbon surfaces by heat treatment in an argon atmosphere. X-ray photoelectron spectroscopy, Raman, and FTIR spectra of the modified surfaces showed that the molecules were intact after the 400 °C heat treatment but that the alkyne group had reacted with the surface to form a covalent bond. Alkynes with ferrocene and porphyrin centers exhibited chemically reversible voltammetric waves that could be cycled many times. Atomic force microscopy of the modified surfaces indicated a thickness of the molecular layer consistent with monolayer coverage, and surface coverage determined by voltammetry was also in the monolayer range. Raman spectroscopy of the porphyrin monolayers formed from a porphyrin alkyne showed no evidence for dimer formation, although multilayer formation may occur at undetected levels. FTIR spectra of the porphyrin-modified carbon surfaces were well-defined, similar to the parent molecule, and indicative of an average tilt angle between the porphyrin plane and the surface normal of 37°. The bond between the molecular monolayer and the carbon surface was quite stable, withstanding sonication in tetrahydrofuran, mild aqueous acid and base, and repeated voltammetric cycling in propylene carbonate electrolyte. Heat treatment of alkynes and alkenes appears to be a generally useful method for modifying carbon surfaces, which can be applied to both aromatic and aliphatic molecules.
Quantum chemistry study of proteins in bacterial photosynthetic reaction center (2001)

Quantum chemistry study on proteins L and M in the Rhodopseudomonas viridis (Rh. viridis) photosynthetic reaction center (PRC) are presented. The calculations were performed at ab initio level with Clementi minimal basis set by means of the overlapping-dimer approximation (ODA)–extended negative factor counting (ENFC) method. Additional point charges were added to individual residues to simulated ionized aqueous environment of the proteins in the calculations. Meanwhile, the electronic structure of protein complex MH (protein M plus the α-helix segment of protein H) was studied as well to examine the weak interaction between proteins M and H. As the first case of global quantum chemistry calculation for proteins in PRC, details of the electronic structure and the influence of proteins on the electron transfer process (ET) were studied. Moreover, new three-dimensional structure plots of subunit L and M were given based on the distribution of the components of frontier orbitals in order to more clearly understand the structure–function relationship of the proteins in electron transfer reactions. Calculation results indicated that the components of frontier orbitals are extremely localized at individual residues. Amino acid residues, having contributed to the frontier orbitals of protein L, are located at the flexible random area of L, while those having contributed to the frontier orbitals of protein M are located at the rigid α-helix area. This asymmetry of proteins L and M provides new understanding the ET reaction that takes place mainly along branch L in the PRC of Rh. viridis. Meanwhile, there is frontier orbital localized amino acid distribution around the V-shaped pocket areas of protein L (M) that were expected to have an important interaction with QA (QB). All results indicate that protein provided a heterogeneous environment for pigment molecules and some important interaction between protein residues and pigment molecules are worthy of further investigation. © 2001 John Wiley & Sons, Inc. Int J Quant Chem 83: 30–40, 2001
Gram stain method shows better sensitivity than clinical criteria for detection of bacterial vaginosis in surveillance of pregnant, low-income women in a clinical setting (1998)

The Gram stain method is a rapid and cost-effective test that is also highly reproducible and readily available in many laboratories. These features make the Gram stain method a more desirable screening procedure for bacterial vaginosis in a clinic population.
Rhodium carbonyl catalyzed carbonylation of unsaturated compounds. 2. Synthesis of 5-alkoxy-2(5H)-furanones by the carbonylation of acetylenes in alcohol (1983)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRhodium carbonyl catalyzed carbonylation of unsaturated compounds. 2. Synthesis of 5-alkoxy-2(5H)-furanones by the carbonylation of acetylenes in alcoholTakaya Mise, Pangbu Hong, and Hiroshi YamazakiCite this: J. Org. Chem. 1983, 48, 2, 238–242Publication Date (Print):January 1, 1983Publication History Published online1 May 2002Published inissue 1 January 1983https://pubs.acs.org/doi/10.1021/jo00150a018https://doi.org/10.1021/jo00150a018research-articleACS PublicationsRequest reuse permissionsArticle Views198Altmetric-Citations23LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts