gebhart/patrepeval huggingface dataset:
Handbook of multisensor data fusion (2001)

MULTISENSOR DATA FUSION Introduction to Multisensor Data Fusion, D. Hall and J. Llinas The JDL Data Fusion Process Model, A. Steinberg and C. Bowman Introduction to the Algorithms of Data Association in Multiple-Target Tracking, J.K. Uhlmann The Principles and Practice of Image and Spatial Data Fusion, E. Waltz Data Registration, R. Brooks and L. Grewe Data Fusion Automation: A Top-Down Perspective, R. Antony Contrasting Approaches to Combine Evidence, J. Carl ADVANCED TRACKING AND ASSOCIATION METHODS Target Tracking Using Probabilistic Data Association-Based Techniques and Applications to Sonar, Radar, and EO Sensors, T. Kirubarajan and Y. Bar-Shalom An Introduction to the Combinatorics of Optimal and Approximate Data Association, J.K. Uhlmann A Bayesian Approach to Multiple-Target Tracking, L. Stone Data Association Using Multiple Frame Assignments, A. Poore, S. Lu, and B.J. Suchomel General Decentralized Data Fusion with Covariance Intersection, S. Julier and J. Uhlmann Data Fusion in Non-Linear Systems, S. Julier and J. Uhlmann Random Set Theory for Target Tracking and Identification, R. Mahler SYSTEMS ENGINEERING AND IMPLEMENTATION Requirements Derivation for Data Fusion Systems, E. Waltz and D. Hall A Systems Engineering Approach for Implementing Data Fusion Systems, C. Bowman and A. Steinberg Studies and Analyses with Project Correlation: An In-Depth Assessment of Correlation Problems and Solution Techniques, J. Llinas, L. McConnell, C. Bowman, D. Hall, and P. Applegate Data Management Support to Tactical Data Fusion, R. Antony Removing the HCI Bottleneck: How the Human-Computer Interface (HCI) Affects the Performance of Data Fusion Systems, M.J. Hall, S.A. Hall, and T. Tate Assessing the Performance of Multisensor Fusion Processes, J. Llinas Dirty Secrets in Data Fusion, D. Hall and A. Steinberg SAMPLE APPLICATIONS A Survey of Multisensor Data Fusion Systems, M. Nichols Data Fusion for Developing Predictive Diagnostics for Electromechanical Systems, C. Byington and A. Garga Information Technology for NASA in the 21st Century, R.J. Hansen, D. Cooke, K. Ford, and S. Zornetzer Data Fusion for a Distributed Ground-Based Sensing System, R. Brooks An Evaluation Methodology for Fusion Processes Based on Information Needs, H. Keithley RESOURCES Web Sites Related to Multi-Sensor Data Fusion Index
Misleading worm signature generators using deliberate noise injection (2006)

Several syntactic-based automatic worm signature generators, e.g., Polygraph, have recently been proposed. These systems typically assume that a set of suspicious flows are provided by a flow classifier, e.g., a honeynet or an intrusion detection system, that often introduces "noise" due to difficulties and imprecision inflow classification. The algorithms for extracting the worm signatures from the flow data are designed to cope with the noise. It has been reported that these systems can handle a fairly high noise level, e.g., 80% for Polygraph. In this paper, we show that if noise is introduced deliberately to mislead a worm signature generator, a much lower noise level, e.g., 50%, can already prevent the system from reliably generating useful worm signatures. Using Polygraph as a case study, we describe a new and general class of attacks whereby a worm can combine polymorphism and misleading behavior to intentionally pollute the dataset of suspicious flows during its propagation and successfully mislead the automatic signature generation process. This study suggests that unless an accurate and robust flow classification process is in place, automatic syntactic-based signature generators are vulnerable to such noise injection attacks.
Analysis of the Induced Stresses in Silicon During Thermcompression Cu-Cu Bonding of Cu-Through-Vias in 3D-SIC Architecture (2007)

A new approach to 3D stacking of chips is being developed at IMEC and is called 3D-stacked IC (3D-SIC). In this approach, interconnection between strata is achieved by thermo-compression bonding of Cu-vias to a Cu-landing pad. In this paper we use finite element methods to study the influence of the resultant induced stresses in silicon as a result of CTE mismatch between silicon and copper and that also caused by the applied thermo-compression bonding force. Bonding temperature is found to be the main cause of induced stresses during thermo-compression bonding. The induced stresses decreased with a decrease in the silicon thickness. The keep-away-zone of the transistors from the influence of stresses from the Cu-vias is found to be dependent on the diameter of the Cu-via and the doping concentration of the transistors.
Deregulation of Listeria monocytogenes virulence gene expression by two distinct and semi-independent pathways (2004)

Expression of the major virulence cluster in Listeria monocytogenes is positively regulated by the transcription factor PrfA and is influenced by several environmental factors, including the presence of readily metabolized carbohydrates such as cellobiose and glucose. Although little is understood about the mechanisms through which environmental factors influence expression of the PrfA regulon, evidence for structural and functional similarities of PrfA to the CRP-FNR family of regulatory proteins suggests the possibility that PrfA activity could be modulated by a small molecule ligand. The identity of components of the PrfA-associated regulatory pathway was sought through the isolation of mutants that exhibit high levels of PrfA-controlled gene expression in the presence of cellobiose or glucose. Here are described the properties and preliminary genetic analysis in two different genetic loci, gcr and csr, both unlinked by general transduction to the major virulence cluster. A mutation in gcr deregulates the expression of PrfA-controlled genes in the presence of several repressing sugars and other environmental conditions, a phenotype similar to that of a G145S substitution in PrfA itself. A mutation in the csr locus, within csrA, results in a cellobiose-specific defect in virulence gene regulation. Gene products encoded by the csr locus share homology with proteins involved in the sensing and transport of beta-glucosides in other bacteria. Mutations in both gcr and csr are required for full relief of cellobiose-mediated repression of the PrfA regulon. These results suggest the existence of two semi-independent pathways for cellobiose-mediated repression and further reconcile conflicting reports in previous literature concerning the repressive effects of carbohydrates on virulence gene expression in L. monocytogenes.
Genetic and Environmental Influences on Premature Death in Adult Adoptees (1988)

To assess genetic and environmental influences on adult mortality, we followed 960 families that included children born during the period 1924 through 1926 who were placed early in life with adoptive parents unrelated to them. We evaluated the risks of dying from all causes or from specific groups of causes between the ages of 16 and 58 years for adoptees with a biologic or adoptive parent who died of the same cause before the age of either 50 or 70. We compared these risks with the adoptees' risk of dying from the same causes between the ages of 16 and 58 when either the biologic or adoptive parents were still alive at the ages of 50 and 70. The death of a biologic parent before the age of 50 resulted in relative risks of death in the adoptees of 1.71 (95 percent confidence interval, 1.14 to 2.57) for all causes, 1.98 (1.25 to 3.12) for natural causes, 5.81 (2.47 to 13.7) for infections, 4.52 (1.32 to 15.4) for cardiovascular and cerebrovascular causes, and 1.19 (0.16 to 8.99) for cancers. The death of an adoptive parent resulted in relative risks of death in the adoptees that were close to unity for all causes, natural causes, and infections, 3.02 (0.72 to 12.8) for vascular causes, and 5.16 (1.20 to 22.2) for cancers. A similar but weaker pattern was observed when either a biologic or adoptive parent died before the age of 70. We conclude that premature death in adults has a strong genetic background--especially death due to infections and vascular causes.(ABSTRACT TRUNCATED AT 250 WORDS)
An Adverse Role for Matrix Metalloproteinase 12 after Spinal Cord Injury in Mice (2003)

We investigated the role of matrix metalloproteinases (MMPs) in acute spinal cord injury (SCI). Transcripts encoding 22 of the 23 known mammalian MMPs were measured in the mouse spinal cord at various time points after injury. Although there were significant changes in the expression levels of multiple MMPs, MMP-12 was increased 189-fold over normal levels, the highest of all MMPs examined. To evaluate the role of MMP-12 in SCI, spinal cord compression was performed in wild-type (WT) and MMP-12 null mice. Behavioral analyses were conducted for 4 weeks using the Basso-Beattie-Bresnahan (BBB) locomotor rating scale as well as the inclined plane test. The results show that MMP-12 null mice exhibited significantly improved functional recovery compared with WT controls. Twenty-eight days after injury, the BBB score in the MMP-12 group was 7, representing extensive movement of all three hindlimb joints, compared with 4 in the WT group, representing only slight movement of these joints. Furthermore, MMP-12 null mice showed recovery of hindlimb strength more rapidly than control mice, with significantly higher inclined plane scores on days 14 and 21 after SCI. Mechanistically, there was decreased permeability of the blood-spinal barrier and reduced microglial and macrophage density in MMP-12 null mice compared with WT controls. This is the first study to profile the expression patterns of a majority of the known MMPs after spinal cord compression. The data indicate that MMP-12 expression after spinal cord trauma is deleterious and contributes to the development of secondary injury in SCI.
Fedbatch Operation Using Clostridium acetobutylicum Suspension Culture as Biocatalyst for Enhancing Hydrogen Production (2003)

We demonstrated the feasibility of fedbatch operation using Clostridium acetobutylicum suspension culture as a biocatalyst for the continuous production of hydrogen. The optimum operating pH and temperature of the current cultivation system for hydrogen production were pH 6.0 and 37 degrees C, respectively. The volumetric loading of the bioreactor for hydrogen production can be as high as 650 mmol hydrogen/L culture with a yield at approximately 2.0 mol hydrogen/mol glucose. Acetate and butyrate made up approximately 80% of the total metabolites. The inhibitory effect from the two metabolites on the hydrogen production process was investigated. Butyrate at a concentration higher than 13 g/L significantly inhibited not only cell growth but also hydrogen production (i.e., specific hydrogen production rate). Acetate appears to be less toxic than butyrate to the hydrogen production process. While significantly inhibiting cell growth, acetate hardly affected hydrogen production. Finally, the factors limiting cultivation performance were discussed and possible strategies for enhancing the production of hydrogen were proposed.
High performance 5nm radius Twin Silicon Nanowire MOSFET (TSNWFET) : fabrication on bulk si wafer, characteristics, and reliability (2006)

For the first time, we have successfully fabricated gate-all-around twin silicon nanowire transistor (TSNWFET) on bulk Si wafer using self-aligned damascene-gate process. With 10nm diameter nanowire, saturation currents through twin nanowires of 2.64 mA/mum, 1.11 mA/mum for n-channel TSNWFET and p-channel TSNWFET are obtained, respectively. No roll-off of threshold voltages, ~70 mV/dec. of substhreshold swing (SS), and ~20 mV/V of drain induced barrier lowering(DIBL) down to 30 nm gate length are observed for both n-ch and p-ch TSNWFETs
Synthetic methods and reactions. 62. Transformations with chlorotrimethylsilane/sodium iodide, a convenient in situ iodotrimethylsilane reagent (1979)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthetic methods and reactions. 62. Transformations with chlorotrimethylsilane/sodium iodide, a convenient in situ iodotrimethylsilane reagentGeorge A. Olah, Subhash C. Narang, B. G. Balaram Gupta, and Ripudaman MalhotraCite this: J. Org. Chem. 1979, 44, 8, 1247–1251Publication Date (Print):April 1, 1979Publication History Published online1 May 2002Published inissue 1 April 1979https://pubs.acs.org/doi/10.1021/jo01322a012https://doi.org/10.1021/jo01322a012research-articleACS PublicationsRequest reuse permissionsArticle Views6889Altmetric-Citations444LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
[Topical treatment of some dystrophic and inflammatory lesions of the skin and soft tissues]. (1978)

An investigation has been carried out on lysozyme cleasing antiphlogistic granulogenic activity when topically applied to various lesions such as varicous ulcers, bed sores, herpetic infections or actinic ulcerative processes. 38 patients who had undergone surgery and were affected with these lesions, were treated with lysozyme ointment applied twice daily for 15 days. Parameters for evaluating the therapeutic effect of the drug were, besides the typical subjective symptomatology, planimetry of the lesions, hyperemia and perilesional erythema. At the end of the investigation it was observed that lysozyme applications had favourable restorative effects and, in the case of herpetic lesions, complete resolution was achieved. Tolerance was satisfactory, although in 2 cases treatment had to be precautionarily discontinued having the subject complained of reacutization of pruritus.
Circles And Seeds: Adapting Kpelle Ideas About Music Performance For Collaborative Digital Music Performance (2002)

The use of free gesture in making music has usually been confined to instruments that use direct mappings between movement and sound space. Here we demonstrate the use of categories of gesture as the basis of musical learning and performance collaboration. These are used in a system that reinterprets the approach to learning through performance that is found in many musical cultures and discussed here through the example of Kpelle music.
Immunological properties of Escherichia coli heat-stable enterotoxins: development of a radioimmunoassay specific for heat-stable enterotoxins with suckling mouse activity (1981)

Antiserum was raised against the purified heat-stable enterotoxin (ST) produced by enterotoxigenic Escherichia coli strain 431, a class II porcine enteropathogen. The antiserum was used to examine the antigenic determinants of STs produced by enterotoxigenic strains of different host origins and develop a sensitive radioimmunoassay specific for ST having biological activity in suckling mice and piglets (STA). The antiserum neutralized one effective dose of toxin at a dilution of 1:5,000 and neutralized approximately 40 microgram of toxin per ml of serum. In the radioimmunoassay, protein A-bearing staphylococci was used as the primary solid-phase adsorbent. The purified STs produced by a class I enteropathogen (strain 667) and by a bovine enterotoxigenic strain (B-41) exhibited patterns of competitive inhibition identical to those of homologous unlabeled strain 431 ST in the radioimmunoassay when specific antibody to strain 431 ST was used. The levels of ST in culture supernatants determined by the suckling mouse assay correlated with the concentrations of toxin measured by the radioimmunoassay. The antiserum was specific for STA produced by enterotoxigenic E. coli of porcine, bovine, and human origins and did not react with heat-labile enterotoxin or with ST that had biological activity in piglets but not in suckling mice (STB). These results suggest that STA molecules having different host origins share at least one antigenic determinant.
Promoting Axon Regeneration in the Adult CNS by Modulation of the PTEN/mTOR Pathway (2008)

The failure of axons to regenerate is a major obstacle for functional recovery after central nervous system (CNS) injury. Removing extracellular inhibitory molecules results in limited axon regeneration in vivo. To test for the role of intrinsic impediments to axon regrowth, we analyzed cell growth control genes using a virus-assisted in vivo conditional knockout approach. Deletion of PTEN (phosphatase and tensin homolog), a negative regulator of the mammalian target of rapamycin (mTOR) pathway, in adult retinal ganglion cells (RGCs) promotes robust axon regeneration after optic nerve injury. In wild-type adult mice, the mTOR activity was suppressed and new protein synthesis was impaired in axotomized RGCs, which may contribute to the regeneration failure. Reactivating this pathway by conditional knockout of tuberous sclerosis complex 1, another negative regulator of the mTOR pathway, also leads to axon regeneration. Thus, our results suggest the manipulation of intrinsic growth control pathways as a therapeutic approach to promote axon regeneration after CNS injury.
Bovine Inner Cell Mass Cells as Donor Nuclei in the Production of Nuclear Transfer Embryos and Calves1 (1994)

Bovine inner cell mass (ICM) cells were used as donor nuclei in nuclear transfer procedures to determine their totipotency. ICMs were isolated by immunosurgery from expanded Day 7-9 blastocysts that had been produced in vitro. Each individual ICM cell was transferred into an enucleated oocyte. Oocytes were checked for enucleation with Hoechst dye to ensure that all DNA was removed, thus eliminating the possibility of parthenogenetic development. ICM cell-oocyte units were fused by a brief electrical pulse (110 V DC, 15 microseconds in a 500-microns chamber), and the resulting zygotes were placed into CR1 bovine embryo culture medium supplemented with amino acids and fetal calf serum. The nuclear transfer embryos were scored for development to the blastocyst stage on Day 7 (day of fusion = 0). A total of 948 nuclear transfers were completed in 25 trials. In 12 of the trials, development to the blastocyst stage (5%, 30 of 629) was observed. This resulted in an overall developmental rate of 3% for all trials. Twenty-six of the ICM-derived blastocysts were transferred. The initial pregnancy rate at 30 days was 23% with six pregnant recipients. Two pregnancies were lost after 60 days, and four calves were born, two of which were stillborn. These results demonstrated that nucleic of ICM cells from expanded bovine blastocysts were pluripotent, if not in fact totipotent, since these nuclei after nuclear transfer to enucleated oocytes could direct embryonic and fetal development resulting in live offspring.
Transactivation-Competent Bovine Papillomavirus E2 Protein Is Specifically Required for Efficient Repression of Human Papillomavirus Oncogene Expression and for Acute Growth Inhibition of Cervical Carcinoma Cell Lines (1998)

The papillomavirus E2 proteins can function as sequence-specific transactivators or transrepressors of transcription and as cofactors in viral DNA replication. We previously demonstrated that acute expression of the bovine papillomavirus type 1 (BPV1) E2 protein in HeLa and HT-3 cervical carcinoma cell lines greatly reduced cellular proliferation by imposing a specific G1/S phase growth arrest. In this report, we analyzed the effects of a panel of point mutations in the BPV1 E2 protein to identify the functional requirements for acute growth inhibition. Disruption of E2-specific transactivation by mutations within either the transactivation domain or the DNA binding domain severely impaired E2-mediated growth inhibition in HeLa and HT-3 cells, even though these mutants retain various other E2 activities. This result indicates that functional transactivation activity is required for acute E2-mediated growth inhibition. HeLa cells, which contain a wild-type p53 gene, and HT-3 cells, which contain a transactivation-defective p53 gene, exhibited similar responses to the E2 mutants, suggesting that identical functions of the E2 protein were required for growth arrest regardless of p53 status. Replacement of the E2 transactivation domain with that of the herpes simplex virus VP16 generated a chimeric transactivator that efficiently stimulated expression of an E2-responsive reporter plasmid yet was completely defective for growth inhibition, suggesting that an E2-specific transactivation function is required for growth arrest. Surprisingly, the transactivation-defective E2 mutants were also markedly defective in their ability to repress transcription of the native human papillomavirus type 18 (HPV18) E6/E7 oncogenes in HeLa cells and of the HPV18 promoter present in a transfected reporter plasmid. These mutants were also defective in their ability to increase p53 levels. Therefore, efficient repression of the HPV18 promoter in HeLa cells is not merely a consequence of the binding of an E2 protein to appropriately situated binding sites in the promoter.
Nucleotide sequence of the 3' end of MCF 247 murine leukemia virus (1983)

We isolated DNA clones of MCF 247, a leukemogenic, recombinant type C virus obtained from the thymus of an AKR mouse. We determined the nucleotide sequence of the viral long terminal repeat (LTR) and the 3' end of env, and we compared the sequences to corresponding sequences of the genome of Akv virus, the putative ecotropic parent of MCF 247. By analogy with Moloney leukemia virus, we identified the amino terminus of Prp15E, the C-terminal proteolytic cleavage product of env and precursor to mature virion p15E. In MCF 247 the presumptive Prp15E is encoded by a 603-nucleotide open reading frame. The majority of this sequence is identical to that of Akv. However, a recombination event near the 3' end of the Prp15E-coding region introduces nonecotropic sequences into MCF 247, and these extend to the 3' end through the U3 portion of the LTR. The U3 regions of Akv and MCF 247 are about 83% homologous. The R and U5 regions of the LTR of MCF 247 and Akv are identical. Large RNase T1-resistant oligonucleotides analyzed previously in numerous ecotropic and MCF viral genomes were located within the Akv and MCF 247 DNA sequences. The resulting precise T1 oligonucleotide maps of the 3' ends of MCF viral genomes reveal that the biologically defined, leukemogenic class I MCFs isolated from thymic neoplasms of inbred mice all share the sequence pattern seen in MCF 247, a representative of this group; they possess recombinant Prp15E genes and derive U3 from their nonecotropic parents.