gebhart/patrepeval huggingface dataset:
Antiresonant reflecting photonic crystal optical waveguides (2002)

We propose a simple analytical theory for low-index core photonic bandgap optical waveguides based on an antiresonant reflecting guidance mechanism. We identify a new regime of guidance in which the spectral properties of these structures are largely determined by the thickness of the high-index layers and the refractive-index contrast and are not particularly sensitive to the period of the cladding layers. The attenuation properties are controlled by the number of high/low-index cladding layers. Numerical simulations with the beam propagation method confirm the predictions of the analytical model. We discuss the implications of the results for photonic bandgap fibers.
Complement and Leukocyte-Mediated Pulmonary Dysfunction in Hemodialysis (1977)

During hemodialysis, cardiopulmonary decompensation may appear in uremic patients, possibly caused by plugging of pulmonary vessels by leukocytes. In 34 patients we noted leukopenia (20% of initial levels) during hemodialysis that in 15 was associated with impaired pulmonary function. When we infused autologous plasma, incubated with dialyzer cellophane, into rabbits and sheep, sudden leukopenia and hypoxia occurred, with doubling of pulmonary-artery pressures and quintupling of pulmonary-lymph effluent. Histologic examination showed severe pulmonary-vessel-leukostasis and interstitial edema. The syndrome was prevented by preinactivation of complement but was reproduced by infusions of plasma in which complement was activated by zymosan. Thus, acute pulmonary dysfunction from complement-mediated leukostasis may play a major part in the acute cardiopulmonary complications of cellophane-membrane hemodialysis.
Mode of Sensitivity and Resistance of Vaccinia Virus Replication to Interferon (1986)

In this study we show that vaccinia virus replication can be sensitive or resistant to interferon (IFN) in the same strain of mouse L cells. When IFN-treated L cells were maintained in suspension culture, infection led to a rapid inhibition of both viral and cellular protein synthesis together with breakdown of viral RNA and of rRNA. When IFN-treated L cells were maintained in monolayer culture, infection did not lead to significant inhibition of viral protein or RNA synthesis and breakdown of viral or of rRNA was not observed. The resistance of vaccinia virus replication to IFN was not dependent on the input multiplicity or state of growth of the cells (actively dividing or resting). Qualitative and quantitative differences in viral transcription and translation were observed between the two virus-cell systems. Our findings are consistent with the hypothesis that the sensitivity or resistance of vaccinia virus to IFN is mediated by specific viral products that act as activators or selective inhibitors of, at least, the dsRNA-dependent ppp(A2'p)nA synthetase/RNase system.
Analysis of Filovirus Entry into Vero E6 Cells, Using Inhibitors of Endocytosis, Endosomal Acidification, Structural Integrity, and Cathepsin (B and L) Activity (2007)

Ebola and Marburg viruses are believed to enter host cells by receptor-mediated endocytosis. The process has been studied through the use of inhibitors that affect host cell properties and recombinant pseudotyping systems in which filovirus structural glycoproteins mediate entry of foreign virus particles. The aim of the present study was to determine the effects of such treatments on the entry of wild-type filoviruses. Vero E6 cells were exposed to various inhibitors before, during, and after infection with filoviruses. Infected cultures were harvested early (18-24 h) and late (72 h) after infection, and effects of treatment on entry were measured by fluorescent antibody staining of cells or by antigen capture immunoassays, respectively. These prelimary results suggest that filoviruses enter host cells through receptor-mediated endocytosis via clathrin-coated pits and caveolae, that actin filaments and microtubules are important in the entry process, and that proteolytic digestion of glycoprotein 1 by endosomal proteases facilitates entry. These observations obtained using wild-type viruses confirm the results of studies utilizing recombinant systems and offer additional insights into filovirus entry.
Partially preemptible hash joins (1993)

With the advent of real-time and goal-oriented database systems, priority scheduling is likely to be an important feature in future database management systems. A consequence of priority scheduling is that a transaction may lose its buffers to higher-priority transactions, and may be given additional memory when transactions leave the system. Due to their heavy reliance on main memory, hash joins are especially vulnerable to fluctuations in memory availability. Previous studies have proposed modifications to the hash join algorithm to cope with these fluctuations, but the proposed algorithms have not been extensively evaluated or compared with each other. This paper contains a performance study of these algorithms. In addition, we introduce a family of memory-adaptive hash join algorithms that turns out to offer even better solutions to the memory fluctuation problem that hash joins experience.
Facile Syntheses and Multi-orthofunctionalizations of Tertiary Benzamides (1993)

Good yields were usually obtained in Pd(O)-catalyzed Suzuki aryl-aryl coupling reaction, even when both coupling partners had an ortho tertiary benzamide functional group. The direct ortho functionalization of oligomeric tertiary benzamides at Snieckus condition is dependent on the chain length. Tertiary benzamide 1 can be o,o-dilithiated only by metal-halogen exchange of the 2,6-dihalo-compound. Bis-tertiary benzamide 9 can be o,o'-dilithiated with excess(4.1 equivalents) s-butyllithium/TMEDA as the lithiating agent. Tris-tertiary benzamide 21 is hard to o,o-difunctionalize due to steric interactions among the tertiary benzamide functional groups, and due to steric interactions between these functional groups and others (if present) on the termini of the terphenyl unit.
Accuracy and stability of numerical algorithms (1996)

From the Publisher:
What is the most accurate way to sum floating point numbers? What are the advantages of IEEE arithmetic? How accurate is Gaussian elimination and what were the key breakthroughs in the development of error analysis for the method? The answers to these and many related questions are included here. 
This book gives a thorough, up-to-date treatment of the behavior of numerical algorithms in finite precision arithmetic. It combines algorithmic derivations, perturbation theory, and rounding error analysis. Software practicalities are emphasized throughout, with particular reference to LAPACK and MATLAB. The best available error bounds, some of them new, are presented in a unified format with a minimum of jargon. Because of its central role in revealing problem sensitivity and providing error bounds, perturbation theory is treated in detail. 
Historical perspective and insight are given, with particular reference to the fundamental work of Wilkinson and Turing, and the many quotations provide further information in an accessible format. 
The book is unique in that algorithmic developments and motivations are given succinctly and implementation details minimized, so that attention can be concentrated on accuracy and stability results. Here, in one place and in a unified notation, is error analysis for most of the standard algorithms in matrix computations. Not since Wilkinson's Rounding Errors in Algebraic Processes (1963) and The Algebraic Eigenvalue Problem (1965) has any volume treated this subject in such depth. A number of topics are treated that are not usually covered in numerical analysis textbooks, including floating point summation, block LU factorization, condition number estimation, the Sylvester equation, powers of matrices, finite precision behavior of stationary iterative methods, Vandermonde systems, and fast matrix multiplication. 
Although not designed specifically as a textbook, this volume is a suitable reference for an advanced course, and could be used by instructors at all levels as a supplementary text from which to draw examples, historical perspective, statements of results, and exercises (many of which have never before appeared in textbooks). The book is designed to be a comprehensive reference and its bibliography contains more than 1100 references from the research literature. 
Audience 
Specialists in numerical analysis as well as computational scientists and engineers concerned about the accuracy of their results will benefit from this book. Much of the book can be understood with only a basic grounding in numerical analysis and linear algebra. 
About the Author 
Nicholas J. Higham is a Professor of Applied Mathematics at the University of Manchester, England. He is the author of more than 40 publications and is a member of the editorial boards of the SIAM Journal on Matrix Analysis and Applications and the IMA Journal of Numerical Analysis. His book Handbook of Writing for the Mathematical Sciences was published by SIAM in 1993.
Worldlets---3D thumbnails for wayfinding in virtual environments (1997)

Virtual environment landmarks are essential in wayfinding: they anchor routes through a region and provide memorable destinations to return to later. Current virtual environment browsers provide user interface menus that characterize available travel destinations via landmark textual descriptions or thumbnail images. Such characterizations lack the depth cues and context needed to reliably recognize 3D landmarks. This paper introduces a new user interface affordance that captures a 3D representation of a virtual environment landmark into a 3D thumbnail, called a worldlet. Each worldlet is a miniature virtual world fragment that may be interactively viewed in 3D, enabling a traveler to gain first-person experience with a travel destination. In a pilot study conducted to compare textual, image, and worldlet landmark representations within a wayfinding task, worldlet use significantly reduced the overall travel time and distance traversed, virtually eliminating unnecessary backtracking.
Pulse glucometry: a new approach for noninvasive blood glucose measurement using instantaneous differential near-infrared spectrophotometry (2006)

We describe a new optical method for noninvasive blood glucose (BGL) measurement. Optical methods are confounded by basal optical properties of tissues, especially water and other biochemical species, and by the very small glucose signal. We address these problems by using fast spectrophotometric analysis in a finger, deriving 100 transmittance spectra per second, to resolve optical spectra (900 to 1700 nm) of blood volume pulsations throughout the cardiac cycle. Difference spectra are calculated from the pulsatile signals, thereby eliminating the effects of bone, other tissues, and nonpulsatile blood. A partial least squares (PLS) model is used with the measured spectral data to predict BGL levels. Using glucose tolerance tests in 27 healthy volunteers, periodic optical measurements were made simultaneously with collection of blood samples for in vitro glucose analysis. Altogether, 603 paired data sets were obtained in all subjects and two-thirds of the data or of the subjects randomly selected were used for the PLS calibration model and the rest for the prediction. Bland-Altman and error-grid analyses of the predicted and measured BGL levels indicated clinically acceptable accuracy. We conclude that the new method, named pulse glucometry, has adequate performance for safe, noninvasive estimation of BGL.
Solvolysis of Cyclohexenyliodonium Salt, a New Precursor for the Vinyl Cation: Remarkable Nucleofugality of the Phenyliodonio Group and Evidence for Internal Return from an Intimate Ion-Molecule Pair (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSolvolysis of Cyclohexenyliodonium Salt, a New Precursor for the Vinyl Cation: Remarkable Nucleofugality of the Phenyliodonio Group and Evidence for Internal Return from an Intimate Ion-Molecule PairTadashi Okuyama, Tomoki Takino, Takuya Sueda, and Masahito OchiaiCite this: J. Am. Chem. Soc. 1995, 117, 12, 3360–3367Publication Date (Print):March 1, 1995Publication History Published online1 May 2002Published inissue 1 March 1995https://pubs.acs.org/doi/10.1021/ja00117a006https://doi.org/10.1021/ja00117a006research-articleACS PublicationsRequest reuse permissionsArticle Views2386Altmetric-Citations242LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Phosphorylation by p34cdc2 Protein Kinase Regulates Binding of the Kinesin-related Motor HsEg5 to the Dynactin Subunit p150Glued (1997)

The kinesin-related motor HsEg5 is essential for centrosome separation, and its association with centrosomes appears to be regulated by phosphorylation of tail residue threonine 927 by the p34(cdc2) protein kinase. To identify proteins able to interact with the tail of HsEg5, we performed a yeast two-hybrid screen with a HsEg5 stalk-tail construct as bait. We isolated a cDNA coding for the central, alpha-helical region of human p150(Glued), a prominent component of the dynactin complex. The interaction between HsEg5 and p150(Glued) was enhanced upon activation of p34(CDC28), the budding yeast homolog of p34(cdc2), provided that HsEg5 had a phosphorylatable residue at position 927. Phosphorylation also enhanced the specific binding of p150(Glued) to the tail domain of HsEg5 in vitro, indicating that the two proteins are able to interact directly. Immunofluorescence microscopy revealed co-localization of HsEg5 and p150(Glued) during mitosis but not during interphase, consistent with a cell cycle-dependent association between the two proteins. Taken together, these results suggest that HsEg5 and p150(Glued) may interact in mammalian cells in vivo and that p34(cdc2) may regulate this interaction. Furthermore, they imply that the dynactin complex may functionally interact not only with dynein but also with kinesin-related motors.
A multilayer organic package with 64 dual-polarized antennas for 28GHz 5G communication (2017)

An organic-based multi-layered phased-array antenna package for a 28GHz 5G radio access applications is hereby introduced. The package incorporates 64 dual-polarized antenna elements and features an air cavity common to all antennas. Direct antenna probing measurements of the package show over 3GHz bandwidth and 3dBi gain at 28GHz. A phased array transceiver module has been developed with the package and four SiGe BiCMOS ICs are attached using flip-chip assembly. Module-level measurements in TX mode show 54dBm EIRP and near-ideal 35dB gain increase for 64-element power combining. 64-element radiation pattern measurements are reported with a steering range of > ±40 degrees without tapering in off-boresight direction.
On the universality of inversion layer mobility in Si MOSFET's: Part II-effects of surface orientation (1994)

For part I see ibid., vol.41, no.12, pp.2357-62 (1994). This paper reports the studies of the inversion layer mobilities in n-channel MOSFET's fabricated on Si wafers with three surface orientations ([100], [110], and [111]) from the viewpoint of the universal relationship against the effective field, E/sub eff/(=q(N/sub dpl/+/spl eta//spl middot/N/sub s/)//spl epsi/Si). It is found that the universality does hold for the electron mobilities on [110] and [111], when the value of /spl eta/ is taken to be 1/3, different from the electron mobility on [100], where /spl eta/ is 1/2. Also, the E/sub eff/ dependence of the electron mobility is found to differ among [100], [110], and [111] surfaces. This is attributed to the differences in the E/sub eff/ dependence of the mobility limited by surface roughness scattering among the orientations. The origins of E/sub eff/ and /spl eta/ are discussed on the basis of the relaxation time approximation for a 2DEG (2-dimensional electron gas). While the surface orientation dependence of /spl eta/ in phonon scattering can be understood in terms of the subband occupation, it is found that the theoretical formulation of surface roughness scattering, used currently, needs to be refined in order to explain the differences in E/sub eff/ dependence and the value of /spl eta/ among the three orientations.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Familial predisposition for otitis media in Apache Indians at Canyon Day, Arizona (1987)

The familial occurrence of otitis media was studied in White Mountain Apache Indians at Canyon Day, Arizona. Of the 760 residents, 366 persons were seen during a village survey for otitis media. There were 133 first-degree relatives involving 113 first-degree relative pairs. Of these, there were 38 children involving 19 separate sibling pairs, for whom age- and sex-matched controls could be assigned. Tympanic membrane scarring was assumed to be a marker of prior otitis media. The findings suggested (P less than .01 for the nonindependent first-degree relative pairs, and P less than .05 for the independent sibling pairs) a familial predisposition. With the additional assumption that the severity of tympanic membrane scarring can be ranked, no association of severity of otitis media was apparent in the first-degree relatives.
Organic photochemistry. Part 94. Triethylamine-photosensitized reduction of a ketone via a chemical sensitization mechanism (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOrganic photochemistry. Part 94. Triethylamine-photosensitized reduction of a ketone via a chemical sensitization mechanismZheng Zhi Wu, Gordon L. Hug, and Harry MorrisonCite this: J. Am. Chem. Soc. 1992, 114, 5, 1812–1816Publication Date (Print):February 1, 1992Publication History Published online1 May 2002Published inissue 1 February 1992https://doi.org/10.1021/ja00031a040Request reuse permissionsArticle Views338Altmetric-Citations15LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (696 KB) Get e-Alertsclose Get e-Alerts
Precise Point Positioning with Ambiguity Resolution in Real-Time (2008)

We have developed and implemented a method to
resolve carrier phase ambiguities in precise point
positioning (PPP) mode at the satellite single
difference (difference between two satellites
observed from one receiver) level. The corrections
needed for PPP with single difference ambiguity
resolution can be generated in real-time and
transmitted to static or moving dual frequency GPS
client users. We call the real-time point positioning
with ambiguity resolution “PPP-RTK”.
We demonstrate that “PPP-RTK” has several
significant advantages over PPP positioning without
ambiguity resolution or standard PPP. Compared to
PPP, PPP-RTK converges significantly faster to the
correct position in static and kinematic applications.
In kinematic applications PPP RTK provides superior
positions of the moving platform compared to
standard PPP. PPP-RTK has the main advantage
over traditional network RTK techniques that the
client user of the PPP RTK corrections can be in a
highly kinematic environment like a buoy or an
airplane at a significant distance (several 100 to 1000
km) from the reference network and still achieve 1-2
cm horizontal position accuracy.
This paper summarizes the technique to obtain PPP
and PPP RTK corrections and shows representative
example results
Up-Regulation and Profibrotic Role of Osteopontin in Human Idiopathic Pulmonary Fibrosis (2005)

Our results provide a potential mechanism by which osteopontin secreted from the alveolar epithelium may exert a profibrotic effect in IPF lungs and highlight osteopontin as a potential target for therapeutic intervention in this incurable disease.
Prevention of growth arrest‐induced cell death of vascular smooth muscle cells by a product of growth arrest‐specific gene, gas6 (1996)

We have purified Gas6 as a growth-potentiating factor for vascular smooth muscle cells (VSMCs) [Nakano, T. et al. (1995) J. Biol. Chem. 270, 5702-5705]. However, specific production of Gas6 in growth-arrested cells raises an intriguing question as to the physiological function of Gas6. In this study, we found that serum-starved VSMCs secreted some survival factors and depletion of the factors induced cell death of VSMCs. Finally, we demonstrated that cell death was prevented by the addition of Gas6, suggesting that one of the major biological activities of Gas6 is protection of growth-arrested VSMCs from death.
Energy-efficient processor design using multiple clock domains with dynamic voltage and frequency scaling (2004)

As clock frequency increases and feature size decreases, clock distribution and wire delays present a growing challenge to the designers of singly-clocked, globally synchronous systems. We describe an alternative approach, which we call a multiple clock domain (MCD) processor, in which the chip is divided into several clock domains, within which independent voltage and frequency scaling can be performed. Boundaries between domains are chosen to exploit existing queues, thereby minimizing inter-domain synchronization costs. We propose four clock domains, corresponding to the front end , integer units, floating point units, and load-store units. We evaluate this design using a simulation infrastructure based on SimpleScalar and Wattch. In an attempt to quantify potential energy savings independent of any particular on-line control strategy, we use off-line analysis of traces from a single-speed run of each of our benchmark applications to identify profitable reconfiguration points for a subsequent dynamic scaling run. Using applications from the MediaBench, Olden, and SPEC2000 benchmark suites, we obtain an average energy-delay product improvement of 20% with MCD compared to a modest 3% savings from voltage scaling a single clock and voltage system.
Self-expandable valved stent of large size: off-bypass implantation in pulmonary position (2003)

(a) Off-bypass implantation of self-expandable valved stent is feasible in pulmonary position; (b) off-bypass surgical approach allows for valved stent implantation of adult size with adequate hemodynamic functioning; and (c) intra-vascular ultrasound makes implantation and evaluation easy and reproducible.