gebhart/patrepeval huggingface dataset:
Time course of subjective pain ratings, and wound and leg tenderness after hysterectomy (1997)

These results indicate that wound pressure algometry correlates to postoperative pain at rest and during movement and may be an alternative way of assessing wound pain and tenderness. Increased tenderness to mechanical stimulation remote from the surgical wound could not be demonstrated.
A flying saucer lifted with Coand&#x0103; effect (2014)

In this work, we present a flying saucer, a kind of unmanned aerial vehicle(UAV), lifted based on Coandă effect. Coandă effect is an interesting fluid dynamic phenomenon that the interaction between the flow and curved surfaces produce attraction, which results in the lifting of the object. The flying saucer adopting Coandă effect is easy to hover while keeping its posture stable, and vertical take-off and landing(VTOL) is possible. Its design procedures via optimization and manufacturing procedures are explained in details, and the preliminary tests in the indoor and outdoor are successfully demonstrated.
Chemical Composition and Mosquito Repellency of Essential Oil ofTagetes minutafrom the Southern Slopes of Mount Elgon in Western Kenya (2013)

Ethnopharmacologically, Tagetes minuta has a lot of applications in the history of human life. The study aimed at characterizing the essential oil from fresh aerial parts of T. minuta and evaluating its repellent effect on the host-seeking female Anopheles arabiensis mosquitoes, the vector of African malaria. The oil was obtained by hydrodistillation and analyzed by gas chromatography (GC) and gas chromatographymass spectrometry (GC-MS). Compounds were identified by comparison of their mass spectra with those in Wiley NBS and NIST databases and GC retention times to those of authentic samples. The repellent effect of the essential oil was evaluated using a human-bait technique to simulate field situation. The percentage yield of the essential oil of T. minuta was 0.00029 % w/w with a specific gravity of 0.8953 mg/ml. The oil showed a complex composition of about 119 hydrocarbon compounds and may be richer in monoterpenes (47.90 %) than in any other type of compounds. The main principal constituents of the essential oil of T. minuta included: ocimene, dihydrotagetone, tagetones, ocimenones, piperitenone, 3,9-epoxy-p-metha-1,8(10) diene, βcaryophyllene, bicyclogermacrene and AR-turmerone. Some of these constituents reported in literature have shown insecticidal, acaricidal, pesticidal and/or repellent properties. Although not manifesting a clear general trend, the essential oil however showed a significant dose-response effect of repellency (p < 0.05). More mosquitoes significantly landed and bit the control arm treated with vaseline pure petroleum jelly than the arm treated with the essential oil of T. minuta (p < 0.05), thus showing repellency properties of the oil against An. Arabiensis mosquitoes. Nevertheless, the underlying mechanism of repellency remains unknown. However, the oil may represent a potentially new, most practical and economic way and readily available and applicable malaria vector control tool for incorporation into integrated vector management strategies and contribute to the provision of prophylactic measures, particularly at an individual level.
Synthesis of Terminal Vanadium(V) Imido, Oxo, Sulfido, Selenido, and Tellurido Complexes by Imido Group or Chalcogenide Atom Transfer to Trigonal Monopyramidal V[N3N] (N3N = [(Me3SiNCH2CH2)3N]3-) (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of Terminal Vanadium(V) Imido, Oxo, Sulfido, Selenido, and Tellurido Complexes by Imido Group or Chalcogenide Atom Transfer to Trigonal Monopyramidal V[N3N] (N3N = [(Me3SiNCH2CH2)3N]3-)Christopher C. Cummins, Richard R. Schrock, and William M. DavisCite this: Inorg. Chem. 1994, 33, 7, 1448–1457Publication Date (Print):March 1, 1994Publication History Published online1 May 2002Published inissue 1 March 1994https://pubs.acs.org/doi/10.1021/ic00085a038https://doi.org/10.1021/ic00085a038research-articleACS PublicationsRequest reuse permissionsArticle Views1626Altmetric-Citations117LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Nanofibers and Nanoparticles for Orthopaedic Surgery Applications (2008)

The ability of nanostructures to elicit altered cell behaviors, including cell adhesion, proliferation, orientation, motility, integrin expression, cytoskeletal organization, and modulation of intracellular signaling, has raised heightened interest in these materials for various biomedical applications, including orthopaedic repair and regeneration. Studies have demonstrated that nanofibrous structures can favorably modulate osteoblast, osteoclast, and fibroblast activities toward implant and/or scaffold materials. Nanomaterials based on silver nanoparticles have received significant attention. Apart from their unique wound-healing ability, silver nanoparticles also exhibit high antibacterial properties, making them potential candidates for use in the development of infection-resistant biomaterials.
Thouless-Anderson-Palmer approach for lossy compression (2004)

We study an ill-posed linear inverse problem, where a binary sequence will be reproduced using a sparse matrix. According to the previous study, this model can theoretically provide an optimal compression scheme for an arbitrary distortion level, though the encoding procedure remains an NP-complete problem. In this paper, we focus on the consistency condition for a dynamics model of Markov-type to derive an iterative algorithm, following the steps of Thouless-Anderson-Palmer approach. Numerical results show that the algorithm can empirically saturate the theoretical limit for the sparse construction of our codes, which is also very close to the rate-distortion function.
Can laser speckle flowmetry be made a quantitative tool? (2008)

The ultimate objective of laser speckle flowmetry (and a host of specific implementations such as laser speckle contrast analysis, LASCA or LSCA; laser speckle spatial contrast analysis, LSSCA; laser speckle temporal contrast analysis, LSTCA; etc.) is to infer flow velocity from the observed speckle contrast. Despite numerous demonstrations over the past 25 years of such a qualitative relationship, no convincing quantitative relationship has been proven. One reason is a persistent mathematical error that has been propagated by a host of workers; another is a misconception about the proper autocorrelation function for ordered flow. Still another hindrance has been uncertainty in the specific relationship between decorrelation time and local flow velocity. Herein we attempt to dispel some of these errors and misconceptions with the intent of turning laser speckle flowmetry into a quantitative tool. Specifically we review the underlying theory, explore the impact of various analytic models for relating measured intensity fluctuations to scatterer motion, and address some of the practical issues associated with the measurement and subsequent data processing.
On reliable distributed IPC/RPC design for interactive mobile applications (2010)

The reliable asynchronous Remote Procedure Call (RPC) is widely employed to realize mobile computing applications. However, the high-end mobile computing applications are interactive in nature, which require integration of Inter-Process Communication (IPC) mechanism between a mobile-client process and the remote RPC process executing at a server. This paper proposes the design and implementation of distributed IPC and RPC mechanisms in an integrated framework supporting interactive mobile applications. The framework offers location transparent, reliable and, scalable IPC/RPC integrated-architecture to the interactive mobile applications. The design of the framework considers mobile-client/server computing model supporting doze mode of operations.
T cell receptor peptide vaccination in rheumatoid arthritis: A placebo-controlled trial using a combination of V3, V14, and V17 Peptides (1998)

Objective Restricted T cell receptor (TCR) gene usage has been demonstrated in animal models of autoimmune disease and has resulted in the successful use of TCR peptide therapy in animal studies. This clinical trial was undertaken to determine the safety and efficacy of a combination of Vβ3, Vβ14, and Vβ17 TCR peptides in Freund's incomplete adjuvant (IFA) in patients with rheumatoid arthritis (RA). Methods A double-blind, placebo-controlled, multicenter, phase II clinical trial was undertaken using IR501 therapeutic vaccine, which consists of a combination of 3 peptides derived from TCRs (Vβ3, Vβ14, and Vβ17) in IFA. A total of 99 patients with active RA received either 90 µg (n = 31) or 300 µg (n = 35) of IR501 or IFA alone (n = 33) as a control. The study medication and placebo were administered as a single intramuscular injection (1 ml) at weeks 0, 4, 8, and 20. Results Treatment with IR501 was safe and well tolerated. None of the patients discontinued the trial because of treatment-related adverse events. Efficacy was measured according to the American College of Rheumatology 20% improvement criteria. Using these criteria, patients in both IR501 dosage groups showed improvement in disease activity. In the most conservative analysis used to evaluate efficacy, an intent-to-treat analysis including all patients who enrolled, the 90-µg dosage group showed a statistically significant improvement compared with control patients at the 20-week time point after the third injection. Trends toward improvement were shown in both the 90-µg and the 300-µg dosage groups at week 24 after the fourth injection. Conclusion IR501 therapeutic vaccine therapy was safe and well tolerated, immunogenic, and demonstrated clinical improvement in RA patients. Additional clinical trials are planned to confirm and extend these observations.
Self-adaptive asymmetric on-line boosting for detecting anatomical structures (2012)

In this paper, we propose a self-adaptive, asymmetric on-line boosting (SAAOB) method for detecting anatomical structures in CT pulmonary angiography (CTPA). SAAOB is novel in that it exploits a new asymmetric loss criterion with self-adaptability according to the ratio of exposed positive and negative samples and in that it has an advanced rule to update sample's importance weight taking account of both classification result and sample's label. Our presented method is evaluated by detecting three distinct thoracic structures, the carina, the pulmonary trunk and the aortic arch, in both balanced and imbalanced conditions.
Humoral Immunity to the Opportunistic Pathogen, Pneumocystis, in a Simian Model of HIV Infection. (2010)

The fungal opportunistic pathogen, Pneumocystis jirovecii (formerly Pneumocystis carinii f. sp. hominis) (Pc) is the causative agent of Pneumocystis Pneumonia (PcP) in immunocompromised persons. Despite improvements in anti-retroviral treatments and Pc prophylaxis, Pc remains an important pathogen in immunocompromised populations. Pc colonization, the presence of Pc in subjects without clinical signs or symptoms of PcP, is common in HIV+ subjects; however, the clinical consequences of colonization are undefined. The non-human primate model of Pc infection in simian immunodeficiency virus (SIV)- or chimeric simian-human immunodeficiency virus (SHIV)-infected macaques has been developed to study Pc colonization pathogenesis in the context of AIDS immunosuppression. Using this model, immunologic parameters associated with natural Pc colonization of macaques were evaluated to gain understanding of protective immune responses to Pc. Humoral immunity to the recombinant Pc-antigen, kexin (KEX1), correlated with protection from subsequent Pc colonization, despite declining CD4+ T cells. Furthermore, macaques that remained Pc-negative were protected against lung injury observed in macaques that became Pc-colonized, supporting a role for Pc in pulmonary obstruction development. These experiments suggest KEX1-specific antibodies may provide protection of immunocompromised individuals from developing obstructive pulmonary disease. Because B cell deficits and dysfunctions are reported in HIV+ subjects, we examined peripheral blood B cell populations in SHIV-infected macaques. We report declines in total (CD20+), memory (CD20+CD27+) and IgM+ memory B cell numbers, increased percentages of activated (CD95+) B cells, and hypergammaglobulinemia in SHIV-infected macaques, similar to what has been reported for HIV+ patients, suggesting the relevance of this model for studying HIV-related B cell dysfunctions. Pc colonization status did not correlate with deficits in total B cell populations. Rather, protection from Pc-colonization appears associated with a KEX1-specific memory B cell pool, despite early loss of total CD27+ B cells. These results suggest exposure to Pc prior to immunosuppression, resulting in high levels of circulating antibodies/plasma cells, contributes to maintenance of a Pc-specific memory B cell pool following immunosuppression. These results demonstrate importance of a Pc-specific humoral response in protection from Pc colonization and pulmonary damage, thereby providing a rationale for Pc-KEX1 vaccine development to protect at-risk populations against this opportunistic pathogen.
Injectable, Cellular-Scale Optoelectronics with Applications for Wireless Optogenetics (2013)

Successful integration of advanced semiconductor devices with biological systems will accelerate basic scientific discoveries and their translation into clinical technologies. In neuroscience generally, and in optogenetics in particular, the ability to insert light sources, detectors, sensors, and other components into precise locations of the deep brain yields versatile and important capabilities. Here, we introduce an injectable class of cellular-scale optoelectronics that offers such features, with examples of unmatched operational modes in optogenetics, including completely wireless and programmed complex behavioral control over freely moving animals. The ability of these ultrathin, mechanically compliant, biocompatible devices to afford minimally invasive operation in the soft tissues of the mammalian brain foreshadow applications in other organ systems, with potential for broad utility in biomedical science and engineering.
Radiation‐induced oxidative degradation of poly(vinyl chloride) (1981)

Abstract Gas evolution and oxygen consumption in the γ‐irradiation of PVC were studied. The gas evolution and the oxidative degradation are retarded by the presence of plasticizers and stabilizers. The G (HCI) and G (H 2 ) and 8 and 0.24 for the irradiation of pure PVC under vacuum and 0.02 and 0.14 for that of plasticized PVC, respectively. Gas evolution increases in the presence of oxygen, specially for the pure PVC. The G (–O 2 ) values for the pure and plasticized PVC are 30 and 12, respectively. The dependence of gas evolution and oxygen consumption on the oxygen pressure is more pronounced for the plasticized PVC than pure PVC because the oxygen diffusion is controlled.
Animal model of depression. (1979)

A behavioural procedure is described which may provide an animal model for some aspects of human depression. Rats or mice when forced to swim in a restricted space will rapidly cease attempts to escape and become immobile. Immobility is reduced by many clinically effective antidepressant treatments suggesting that the immobile behaviour may reflect a state of lowered mood in the animal. If so the method could be useful as a simple experimental tool for research into the biology and therapeutics of depression.
Circulating MicroRNAs, miR-21, miR-122, and miR-223, in patients with hepatocellular carcinoma or chronic hepatitis (2010)

Numerous studies have shown that aberrant microRNA (miRNA) expression is associated with the development and progression of various types of human cancer and serum miRNAs are potential biomarkers. This study examined whether some commonly deregulated miRNAs in hepatocellular carcinoma (HCC) are presented in serum of patients with HCC and can serve as diagnostic markers. Serum miRNAs (miR-21, miR-122, and miR-223) were quantified by real-time quantitative RT-PCR in 101 patients with HCC and 89 healthy controls. In addition, 48 patients with chronic type B hepatitis were also analyzed for comparison. We found that the median levels of miR-21, miR-122, and miR-223 were significantly higher in patients with HCC than those in healthy controls (P = 7.48 x 10⁻¹³, P = 6.93 x 10⁻⁹, and P = 3.90 x 10⁻¹², respectively). However, these elevated serum miRNAs were also detected in patients with chronic hepatitis (P = 2.05 x 10⁻¹², P = 4.52 x 10⁻¹⁶, and P = 1.65 x 10⁻¹¹, respectively). Moreover, serum miR-21 and miR-122 in patients with chronic hepatitis were higher than in patients with HCC (P = 3.99 x 10⁻⁴ and P = 4.97 x 10⁻⁸), although no such significant difference was found for miR-223. Receiver-operator characteristic (ROC) curve analyses suggest that these serum miRNAs may be useful markers for discriminating patients with HCC or chronic hepatitis from healthy controls, but not patients with HCC from patients with chronic hepatitis. Our results indicate that serum miR-21, miR-122 and miR-223 are elevated in patients with HCC or chronic hepatitis and these miRNAs have strong potential to serve as novel biomarkers for liver injury but not specifically for HCC.
Automatic Detection of Pulmonary Embolism in CTA Images (2009)

Pulmonary embolism (PE) is a common life-threatening disorder for which an early diagnosis is desirable. We propose a new system for the automatic detection of PE in contrast-enhanced CT images. The system consists of candidate detection, feature computation and classification. Candidate detection focuses on the inclusion of PE--even complete occlusions--and the exclusion of false detections, such as tissue and parenchymal diseases. Feature computation does not only focus on the intensity, shape and size of an embolus, but also on locations and the shape of the pulmonary vascular tree. Several classifiers have been tested and the results show that the performance is optimized by using a bagged tree classifier with two features based on the shape of a blood vessel and the distance to the vessel boundary. The system was trained on 38 CT data sets. Evaluation on 19 other data sets showed that the system generalizes well. The sensitivity of our system on the evaluation data is 63% at 4.9 false positives per data set, which allowed the radiologist to improve the number of detected PE by 22%.
Time and frequency synchronization of orthogonal frequency division multiple access systems (2002)

We propose a non-data aided synchronization algorithm for orthogonal frequency division multiple access systems. The method is applied to both quasisynchronous and asynchronous systems. The proposed algorithm does not require the transmission of training sequences or of repeated symbols and, differently from all available methods, our frequency estimator has performance independent of the channel zero locations. We provide an analytic expression for the variance of the frequency offset estimator and then we validate our theoretical findings with simulation results.
Efficacy and Safety of Nicardipine Prolonged-Release Implants for Preventing Vasospasm in Humans (2002)

Vasospasm was completely prevented for the arteries in thick clot cisterns, when NPRI were placed adjacent to the arteries during surgery. This drug-delivery system offers a promising approach for preventing vasospasm.
Canine transmissible venereal tumor: a large-animal transplantable tumor model. (2005)

The canine transplantable venereal tumor is a naturally occurring transplantable round-cell tumor in dogs. Although experimental transplantable tumor models in rodents and rabbits are readily available, a reliable transplantable tumor model in a large animal that more closely resembles the physical dimensions of humans has not been available. A tumor model in a large animal would have a wide range of biomedical research applications, including the study of various interventional imaging techniques. In this report, we characterize the experimental transplantation of the canine transmissible venereal tumor in the brain, skin, muscle, prostate, lung, liver, and bone of dogs and provide X-ray computed tomographic and magnetic resonance imaging characteristics of the tumors in the brain, muscle, lung, and prostate.
1,2,3‐Triazoles (2005)

Abstract For Abstract see ChemInform Abstract in Full Text.
Explore First, Exploit Next: The True Shape of Regret in Bandit Problems (2018)

We revisit lower bounds on the regret in the case of multiarmed bandit problems. We obtain nonasymptotic, distribution-dependent bounds and provide simple proofs based only on well-known properties of Kullback–Leibler divergences. These bounds show in particular that in the initial phase the regret grows almost linearly, and that the well-known logarithmic growth of the regret only holds in a final phase. The proof techniques come to the essence of the information-theoretic arguments used and they involve no unnecessary complications.
SOI Photonic Wire Waveguide Ring Resonators using MMI Couplers (2006)

We demonstrate a novel SOI photonic wire ring resonator that uses a MMI coupler which has a compact size of 3times9 mum <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> The resonators exhibited quality factor of 5000, and resonance depth of 20 dB
3D Videocommunication (2005)

List of Contributors. Symbols. Abbreviations. Introduction by O. Schreer, P. Kauff, T. Sikora. SECTION I: APPLICATIONS OF 3D VIDEOCOMMUNICATION. 1. History of Telepresence (W.A. IJsselsteijn). 2. 3D TV broadcasting (C. Fehn). 3. 3D in Content Creation and Post-Production (O. Grau). 4. Free Viewpoint Systems (M. Tanimoto). 5. Immersive Videoconferencing (P. Kauff, O. Schreer). SECTION II: 3D DATA REPRESENTATION AND PROCESSING. 6. Fundamentals of Multiple View Geometry (E. Trucco, S. Ivekovic, A. Fusiello). 7. Stereo Analysis (N. Atzpadin, J. Mulligan). 8. Reconstruction of Volumetric 3D Models (P. Eisert). 9. View Synthesis and Rendering Methods (R. Koch, J.-F. Evers-Senne). 10. 3D Audio Capture and Analysis (M. Schwab, P. Noll). 11. Coding and Standardization (A. Smolic, Th. Sikora). SECTION III: 3D REPRODUCTION. 12. Human Factors of 3D Displays (W.A. IJsselsteijn, P.J.H. Seuntiens, L.M.J. Meesters). 13. 3D Displays (S. Pastoor). 14. Mixed Reality Displays (S. Pastoor, C. Conomis). 15. Spatialised Audio and 3D Audio Rendering (Th. Sporer, S. Brix). SECTION IV: 3D DATA SENSORS. 16. Sensor-Based Depth Capturing (Joao G.M. Goncalves, V. Sequeira). 17. Tracking and User Interface for Mixed Reality (T. Ebrahimi, Y. Abdeljaoued, D. Marimon). Index.