gebhart/patrepeval huggingface dataset:
Spatiotemporal Aquatic Field Reconstruction Using Robotic Sensor Swarm (2012)

Monitoring important aquatic processes like harmful algal blooms is of increasing interest to public health, ecosystem sustainability, marine biology, and aquaculture industry. This paper presents a novel approach to spatiotemporal aquatic field reconstruction using inexpensive, low-power, mobile sensing platforms called robotic fish. Robotic fish networks are a typical example of Cyber-Physical Systems where the design of cyber components (sensing, communication, and information processing) must account for inherent physical dynamics of the robots and the aquatic environment. Our approach features a rendezvous-based mobility control scheme where robotic fish collaborate in the form of a swarm to sense the aquatic environment in a series of carefully chosen rendezvous regions. We design a novel feedback control algorithm that maintains the desirable level of wireless connectivity for a sensor swarm in the presence of significant environment and system dynamics. Information-theoretic analysis is used to guide the selection of rendezvous regions so that the spatiotemporal field reconstruction accuracy is maximized subject to the limited sensor mobility. The effectiveness of our approach is validated via implementation on sensor hardware and extensive simulations based on real data traces of water surface temperature field and on-water ZigBee wireless communication.
The G-quartet containing FMRP binding site in FMR1 mRNA is a potent exonic splicing enhancer (2008)

The fragile X mental retardation protein (FMRP) is a RNA-binding protein proposed to post-transcriptionally regulate the expression of genes important for neuronal development and synaptic plasticity. We previously demonstrated that FMRP binds to its own FMR1 mRNA via a guanine-quartet (G-quartet) RNA motif. However, the functional effect of this binding on FMR1 expression was not established. In this work, we characterized the FMRP binding site (FBS) within the FMR1 mRNA by a site directed mutagenesis approach and we investigated its importance for FMR1 expression. We show that the FBS in the FMR1 mRNA adopts two alternative G-quartet structures to which FMRP can equally bind. While FMRP binding to mRNAs is generally proposed to induce translational regulation, we found that mutations in the FMR1 mRNA suppressing binding to FMRP do not affect its translation in cellular models. We show instead that the FBS is a potent exonic splicing enhancer in a minigene system. Furthermore, FMR1 alternative splicing is affected by the intracellular level of FMRP. These data suggest that the G-quartet motif present in the FMR1 mRNA can act as a control element of its alternative splicing in a negative autoregulatory loop.
Optical and electronic properties of sputtered TiNx thin films (1998)

Thin titanium nitride films were deposited by rf reactive sputtering. The N/Ti ratio varied between 0.88 and 1.12. The optical constants have been determined by ellipsometric measurements between 1.5 and 5 eV. The normal reflectivity was measured between 0.5 and 5.5 eV. The results have been fitted by a model dielectric function based on a set of Drude–Lorentz oscillators. In this way the contributions due to free carriers and to interband transitions could be unambiguously sorted out. The analysis of the optical properties sheds light on the nature of the stoichiometry-related defects of TiNx. It is shown that TiN contains one conduction electron per TiN unit, and that in TiNx the square of the plasma frequency varies in a manner indicating a loss of about one electron to each nitrogen interstitial and a gain of about one conduction electron for each nitrogen vacancy. In substoichiometric material the most significant defect is the nitrogen vacancy and in nitrogen-rich TiNx excess nitrogen behaves like an interstitial defect. The occasional presence of titanium defects is also detected.
Effects of tramadol on experimental inflammation (1999)

We examined the ability of the analgesic drug tramadol to affect the development of inflammation in rats. The acute administration of tramadol significantly reduced the edema and the hyperalgesia induced by yeast injection in the paw. Moreover, in the subcutaneous carrageenin-induced inflammation, tramadol reduced the amount of the exudate, as well as the prostaglandin (PG)E2-like bio- and immuno-activity in the exudate; on the contrary, leukotriene (LT)B4 concentrations in the exudate were not changed. However, tramadol did not affect the ability of macrophages to migrate towards the chemotactic peptide N-formyl-L-methionil-L-leucyl-L-phenylalanine (FMLP). Our results suggest that tramadol is able to inhibit the development of different types of inflammation in the rat without affecting immune mechanisms, and contribute to explain the efficacy of this drug in the treatment of inflammatory pain.
The Human Cysteine‐Rich Secretory Protein (CRISP) Family (1996)

We report the isolation and characterisation of cDNAs encoding three different, human members of the cysteine-rich secretory protein (CRISP) family. The novel CRISP-1 exists in five cDNA subtypes differing by the presence or absence of a stretch coding for a C-terminal cysteine-rich domain so far found in all members of the family, and by the length of their 3'-untranslated region. CRISP-2 cDNA corresponds to the previously described TPX1 form, with so far unreported 5'-untranslated sequence heterogeneities while CRISP-3 cDNA codes for a new, unique protein. Northern blot analysis of various human organs indicates that CRISP-1 transcripts are epididymis-specific whereas CRISP-2/TPX1 transcripts are detected mainly in the testis and also in the epididymis. CRISP-3 transcripts are more widely distributed and found predominantly in the salivary gland, pancreas and prostate, and in less abundance in the epididymis, ovary, thymus and colon. A protein reacting with an anti-mouse CRISP-1 antibody was isolated from human epididymal extracts and N-terminal sequencing revealed that it corresponded to the CRISP-1 cDNA we have isolated. In contrast to findings on its rat counterpart epididymal protein DE/acidic epididymal glycoprotein (AEG), no significant association of CRISP-1 with human spermatozoa was observed.
Effect of the ecdysone agonists, RH-2485 and tebufenozide, on the southwestern corn borer, Diatraea grandiosella (1998)

The effect of the ecdysone agonists RH-2485 (proposed name methoxyfenozide) and tebufenozide (RH-5992), was examined on eggs and larvae of the southwestern corn borer, Diatraea grandiosella Dyar. Both compounds exhibited a concentration-dependent ovicidal activity. More than 95% of eggs died when egg masses were dipped in solutions of 100 or 200 mg liter-1 of either compound in acetone+distilled water (1+1 by volume). Although some eggs treated with 1 or 10 mg liter-1 of the compounds hatched, the survival rate was low. Newly hatched larvae were fed for seven days on an artificial diet containing RH-2485 or tebufenozide. The LC50 values were 0·049 mg kg-1 for RH-2485 and 0·185 mg kg-1 for tebufenozide, showing that RH-2485 was about four times more active than was tebufenozide. Although increasing the time of exposure to either compound decreased the LC50 value significantly, the relative potency of RH-2485 versus tebufenozide was not changed. Newly ecdysed 4th-instar larvae fed with diets containing 0·125, 0·25 or 0·5 mg kg-1 RH-2485 or tebufenozide ceased feeding approximately 8 h after exposure, indicating that larvae had prematurely entered a molting cycle. Larvae treated with RH-2485 ecdysed earlier and died more quickly than those treated with tebufenozide. Ingestion of sublethal concentrations of RH-2485 (0·005 and 0·01 mg kg-1) or tebufenozide (0·03 and 0·06 mg kg-1) retarded larval growth, and decreased pupal weight and adult emergence. Increasing exposure time to tebufenozide tended to increase the larval mortality, significantly retarded larval growth, and decreased the mean weights of male and female pupae and adult emergence. RH-2485 (0·125 and 0·25 mg kg-1) and tebufenozide (0·25 and 0·5 mg kg-1) were lethal to newly hatched larvae, even after diets containing these compounds were held for 20 days at 30°C under long days (16 h light: 8 h dark). Our results suggest that field trials to assess the potential of RH-2485 and tebufenozide to control D. grandiosella are warranted. © 1998 SCI
Surface-Enhanced Raman Scattering of 4-Aminothiophenol in Assemblies of Nanosized Particles and the Macroscopic Surface of Silver (2003)

Assemblies consisting of nanosized silver particles, 4-aminothiophenol, and the smooth macroscopic surface of silver metal (Ag/PATP/Ag) were prepared and characterized by surface-enhanced Raman spectroscopy. The Raman spectrum of 4-aminothiophenol in the assemblies is similar to that obtained on the electrochemically roughened electrode, although spectral differences, including slight frequency shifts and changes in relative intensity of the characteristic bands, were observed. The enhancement of the spectrum of 4-aminothiophenol in the assemblies is ascribed to the electromagnetic coupling between the silver particles and the surface of the silver metal. The fact that only the SERS spectrum of 4-aminothiophenol was observed for the assembly, where 4-aminothiophenol is partially replaced with N,N‘-diphenylthiourea, demonstrates that the electromagnetic field is mainly localized in the region between the silver particles and the surface of the silver metal.
High-Resolution Inkjet Printing of All-Polymer Transistor Circuits (2000)

Direct printing of functional electronic materials may provide a new route to low-cost fabrication of integrated circuits. However, to be useful it must allow continuous manufacturing of all circuit components by successive solution deposition and printing steps in the same environment. We demonstrate direct inkjet printing of complete transistor circuits, including via-hole interconnections based on solution-processed polymer conductors, insulators, and self-organizing semiconductors. We show that the use of substrate surface energy patterning to direct the flow of water-based conducting polymer inkjet droplets enables high-resolution definition of practical channel lengths of 5 micrometers. High mobilities of 0.02 square centimeters per volt second and on-off current switching ratios of 10(5) were achieved.
DETECTION OF METAL ION HYDROLYSIS BY COAGULATION: II. THORIUM1,2 (1960)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDETECTION OF METAL ION HYDROLYSIS BY COAGULATION: II. THORIUM1,2E. Matijević, M. B. Abramson, K. F. Schulz, and M. KerkerCite this: J. Phys. Chem. 1960, 64, 9, 1157–1161Publication Date (Print):September 1, 1960Publication History Published online1 May 2002Published inissue 1 September 1960https://pubs.acs.org/doi/10.1021/j100838a013https://doi.org/10.1021/j100838a013research-articleACS PublicationsRequest reuse permissionsArticle Views66Altmetric-Citations40LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Metallo-β-lactamases— new therapeutic challenge (1993)

Microbiology Society journals contain high-quality research papers and topical review articles. We are a not-for-profit publisher and we support and invest in the microbiology community, to the benefit of everyone. This supports our principal goal to develop, expand and strengthen the networks available to our members so that they can generate new knowledge about microbes and ensure that it is shared with other communities.
Predictive Significance of the Alterations of p16INK4A, p14ARF, p53, and Proliferating Cell Nuclear Antigen Expression in the Progression of Cervical Cancer (2004)

Our results suggested that altered states of p16INK4A, p14ARF, p53, and PCNA may be valuable markers to predict the progression of cervical neoplasia.
Acylation-dependent Protein Export inLeishmania (2000)

The surface of the protozoan parasite Leishmania is unusual in that it consists predominantly of glycosylphosphatidylinositol-anchored glycoconjugates and proteins. Additionally, a family of hydrophilic acylated surface proteins (HASPs) has been localized to the extracellular face of the plasma membrane in infective parasite stages. These surface polypeptides lack a recognizable endoplasmic reticulum secretory signal sequence, transmembrane spanning domain, or glycosylphosphatidylinositol-anchor consensus sequence, indicating that novel mechanisms are involved in their transport and localization. Here, we show that the N-terminal domain of HASPB contains primary structural information that directs both N-myristoylation and palmitoylation and is essential for correct localization of the protein to the plasma membrane. Furthermore, the N-terminal 18 amino acids of HASPB, encoding the dual acylation site, are sufficient to target the heterologous Aequorea victoria green fluorescent protein to the cell surface of Leishmania. Mutagenesis of the predicted acylated residues confirms that modification by both myristate and palmitate is required for correct trafficking. These data suggest that HASPB is a representative of a novel class of proteins whose translocation onto the surface of eukaryotic cells is dependent upon a "non-classical" pathway involving N-myristoylation/palmitoylation. Significantly, HASPB is also translocated on to the extracellular face of the plasma membrane of transfected mammalian cells, indicating that the export signal for HASPB is recognized by a higher eukaryotic export mechanism.
High Prevalence of Simian T-Lymphotropic Virus Type L in Wild Ethiopian Baboons (2002)

Simian T-cell leukemia viruses (STLVs) are the simian counterparts of human T-cell leukemia viruses (HTLVs). A novel, divergent type of STLV (STLV-L) from captive baboons was reported in 1994, but its natural prevalence remained unclear. We investigated the prevalence of STLV-L in 519 blood samples from wild-living nonhuman primates in Ethiopia. Seropositive monkeys having cross-reactive antibodies against HTLV were found among 22 out of 40 hamadryas baboons, 8 of 96 anubis baboons, 24 of 50 baboons that are hybrids between hamadryas and anubis baboons, and 41 of 177 grivet monkeys, but not in 156 gelada baboons. A Western blotting assay showed that sera obtained from seropositive hamadryas and hybrid baboons exhibited STLV-L-like reactivity. A PCR assay successfully amplified STLV sequences, which were subsequently sequenced and confirmed as being closely related to STLV-L. Surprisingly, further PCR showed that nearly half of the hamadryas (20 out of 40) and hybrid (19 out of 50) baboons had STLV-L DNA sequences. In contrast, most of the seropositive anubis baboons and grivet monkeys carried typical STLV-1 but not STLV-L. These observations demonstrate that STLV-L naturally prevails among hamadryas and hybrid baboons at significantly high rates. STLV-1 and -2, the close relative of STLV-L, are believed to have jumped across simian-human barriers, which resulted in widespread infection of HTLV-1 and -2. Further studies are required to know if STLV-L is spreading into human populations.
Human tumor antigens for cancer vaccine development (1999)

The adoptive transfer of tumor-infiltrating lymphocytes (TIL) along with interleukin (IL)-2 into autologous patients with cancer resulted in the objective regression of tumor, indicating that T cells play an important role in tumor regression. In the last few years, efforts have been made towards understanding the molecular basis of T-cell-mediated antitumor immunity and elucidating the molecular nature of tumor antigens recognized by T cells. Tumor antigens identified thus far could be classified into several categories: tissue-specific differentiation antigens, tumor-specific shared antigens and tumor-specific unique antigens. CD4+ T cells play a central role in orchestrating the host immune response against cancer, infectious diseases and autoimmune diseases, and we thus have attempted to identify major histocompatibility complex (MHC) class II-restricted tumor antigens as well. The identification of tumor rejection antigens provides new opportunities for the development of therapeutic strategies against cancer. This review will summarize the current status of MHC class I- and class II-restricted human tumor antigens, and their potential application to cancer treatment.
Understanding and Treating Alcohol Dependence (2006)

This article represents the proceedings of a symposium presented at the 158th Annual Meeting of the American Psychiatric Association held in Atlanta, Georgia, on May 24, 2005. The organizer/chairman was Bankole A. Johnson, DSc, MD, PhD. The presentations included the following: (1) Neuropharmacological Basis of Alcohol Dependence, by George F. Koob, PhD; (2) Recent Developments in the Genetics of Alcohol Dependence, by Marc A. Schuckit, MD; (3) New Pharmacological Strategies for Treating Alcohol Dependence, by Barbara J. Mason, PhD; (4) New Medications: The Use of Anticonvulsants, Both Alone and in Combination, with Various Forms of Psychotherapy, by Bankole A. Johnson, DSc, MD, PhD; and (5) Differential Effects of Pharmacological Agents on Craving, by Nassima Ait-Daoud, MD.
Production of dense plasmas in a hypocycloidal pinch apparatus (1977)

A new type of high-power pinch apparatus consisting of disk electrodes was developed and diagnostic measurements to study its mechanism of dense plasma production have been made. The collapse fronts of the current sheets are well organized and dense plasma foci are produced on the axis with radial stability in excess of 5 μsec. A plasma density greater than 1018 cm−3 is determined with Stark broadening and CO2 laser absorption. Essentially complete absorption of a high-energy CO2 laser beam has been observed. A plasma temperature of approximately 1 keV is measured with differential transmission of soft x rays through thin foils. The advantages of this apparatus over the coaxial plasma focus are improvements in (1) plasma volume, (2) stability, (3) containment time, (4) access to additional heating by laser or electron beams, and (5) the possibility of scaling up to a multiple array for high-power operation.
BUSH'S PLAN TO CUT AIR POLLUTION (2002)

RETURN TO ISSUEPREVNewsNEXTBUSH'S PLAN TO CUT AIR POLLUTIONEmissions of nitrogen, mercury, sulfur from power plants targetedJEFF JOHNSONCite this: Chem. Eng. News 2002, 80, 8, 10Publication Date (Print):February 25, 2002Publication History Published online13 November 2010Published inissue 25 February 2002https://pubs.acs.org/doi/10.1021/cen-v080n008.p010ahttps://doi.org/10.1021/cen-v080n008.p010anewsACS PublicationsCopyright © 2002 AMERICAN CHEMICAL SOCIETYArticle Views15Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options SUBJECTS:Air pollution Get e-Alerts
Intracranial pressure regulation: a comparative model of cerebrospinal fluid systems. (1978)

A comparative model of the cerebrospinal fluid (CSF) system in rat, dog and man was derived from manometric data using low volume, short duration infusions into the subarchanoid space in order to describe the mechanisms governing intracranial pressure dynamics. The mathematical model indicates that steady-state elevations of intracranial pressure are regulated primarily by a nonlinear, pressure dependent outflow resistance to CSF reabsorption. While the form of the resistance relationship is similar for the three species tested, differences in the magnitude of CSF outflow parameters are apparent. Model stimulation on a digital computer suggests that parameter changes within the resistance relationship can have a profound effect on the intracranial pressure. In contrast, intracranial compliance acts only to buffer transient changes in volume prior to the establishment of steady-state CSF pressures.
Characterization of FN-C/H-V, a novel synthetic peptide from fibronectin that promotes rabbit corneal epithelial cell adhesion, spreading, and motility. (1993)

These data suggest that the amino acid sequence defined by peptide FN-C/H-V contributes to the adhesion-, spreading-, and motility-promoting activity of the 33/66 kD carboxy-terminal heparin-binding fragments of fibronectin. Given the important role of fibronectin in corneal wound healing, these findings provide additional insight into the complex molecular basis of corneal epithelial cell interactions with fibronectin and may be important in the context of corneal wound healing.
Data link control for multiple input multiple output wireless systems (2006)

This paper investigates the adaptation of data link error control protocols to be more efficient over MIMO wireless links. Data link mechanisms control, among other things, the transmission errors at the link layer, whereas MIMO is a physical layer technology that handles the wireless link with a notably high efficiency and flexibility. A new cross layer protocol is proposed in this paper in order to improve the performance of error control mechanism by making use of the multi-channel transmission characteristics. The main idea is to divide each link layer data unit (block) into sub-blocks and transmit the sub-blocks from different transmit antennas and therefore take advantage of the spatial "diversity". Besides, the division helps the receiver to recognize some error-free parts of a block; consequently new algorithms that exploit this feature are proposed and analyzed. In addition, different methods for providing higher link reliability to retransmitted data are explored.