gebhart/patrepeval huggingface dataset:
Polarization anisotropy in the electroluminescence of m-plane InGaN–GaN multiple-quantum-well light-emitting diodes (2005)

InGaN – GaN multiple-quantum-well light-emitting diodes were fabricated on (101¯0) m plane GaN films grown on (101¯0) m plane 4H–SiC substrates. The [0001] axis of the epitaxial film is parallel to the [0001] axis of the substrate. The surface is striated, with features running perpendicular to the c axis and a maximum surface height difference of 45nm. Electroluminescence shows strong polarization anisotropy, with 7× more light emitted with polarization perpendicular to the c axis compared to parallel to the c axis. An Ahrrenius fit of the polarization ratio indicates that there is a 49meV difference in the energy gap between the two polarization states. This suggests that a high polarization ratio can be maintained at the high temperatures (&amp;gt;150°C) and drive current densities required for high-power light-emitting diode applications.
Lasers in Periodontics: A Review of the Literature (2006)

Based on this review of the literature, there is a great need to develop an evidence-based approach to the use of lasers for the treatment of chronic periodontitis. Simply put, there is insufficient evidence to suggest that any specific wavelength of laser is superior to the traditional modalities of therapy. Current evidence does suggest that use of the Nd:YAG or Er:YAG wavelengths for treatment of chronic periodontitis may be equivalent to scaling and root planing (SRP) with respect to reduction in probing depth and subgingival bacterial populations. However, if gain in clinical attachment level is considered the gold standard for non-surgical periodontal therapy, then the evidence supporting laser-mediated periodontal treatment over traditional therapy is minimal at best. Lastly, there is limited evidence suggesting that lasers used in an adjunctive capacity to SRP may provide some additional benefit.
Cloning the Soil Metagenome: a Strategy for Accessing the Genetic and Functional Diversity of Uncultured Microorganisms (2000)

Recent progress in molecular microbial ecology has revealed that traditional culturing methods fail to represent the scope of microbial diversity in nature, since only a small proportion of viable microorganisms in a sample are recovered by culturing techniques. To develop methods to investigate the full extent of microbial diversity, we used a bacterial artificial chromosome (BAC) vector to construct libraries of genomic DNA isolated directly from soil (termed metagenomic libraries). To date, we have constructed two such libraries, which contain more than 1 Gbp of DNA. Phylogenetic analysis of 16S rRNA gene sequences recovered from one of the libraries indicates that the BAC libraries contain DNA from a wide diversity of microbial phyla, including sequences from diverse taxa such as the low-G+C, gram-positive Acidobacterium, Cytophagales, and Proteobacteria. Initial screening of the libraries in Escherichia coli identified several clones that express heterologous genes from the inserts, confirming that the BAC vector can be used to maintain, express, and analyze environmental DNA. The phenotypes expressed by these clones include antibacterial, lipase, amylase, nuclease, and hemolytic activities. Metagenomic libraries are a powerful tool for exploring soil microbial diversity, providing access to the genetic information of uncultured soil microorganisms. Such libraries will be the basis of new initiatives to conduct genomic studies that link phylogenetic and functional information about the microbiota of environments dominated by microorganisms that are refractory to cultivation.
Nucleic acid enzymes: Playing with a fuller deck (1998)

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences.
Thin-film micropatterning using polymer microspheres (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThin-film micropatterning using polymer microspheresF. Lenzmann, K. Li, A. H. Kitai, and H. D. H. StoverCite this: Chem. Mater. 1994, 6, 2, 156–159Publication Date (Print):February 1, 1994Publication History Published online1 May 2002Published inissue 1 February 1994https://pubs.acs.org/doi/10.1021/cm00038a010https://doi.org/10.1021/cm00038a010research-articleACS PublicationsRequest reuse permissionsArticle Views1065Altmetric-Citations85LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Obstetric embolotherapy: effect on menses and pregnancy. (1997)

Selective embolization of the uterine vessels with gelatin sponge pledgets is a safe and effective method of managing pregnancy-related hemorrhage. Our results suggest that women who undergo this procedure can expect to have a return of normal menses with no adverse effect on fertility.
Eldecalcitol, a vitamin D analog, reduces bone turnover and increases trabecular and cortical bone mass, density, and strength in ovariectomized cynomolgus monkeys (2013)

Vitamin D insufficiency is common in elderly people worldwide, and intake of supplementary calcium and vitamin D is recommended to those with a high risk of fracture. Several clinical studies and meta-analyses have shown that calcium and vitamin D supplementation reduces osteoporotic fractures, and a strong correlation exists between vitamin D status and fracture risk. Vitamin D supplementations improve calcium balance in the body; however, it remains unclear whether vitamin D directly affects bone metabolism. Recently, eldecalcitol (ELD), an active form of vitamin D analog, has been approved for the treatment of osteoporosis in Japan. A 3-year clinical trial showed ELD treatment increased lumbar spine bone mineral density (BMD) and reduced fracture risk in patients with osteoporosis. To evaluate the mechanism of ELD action in bone remodeling, ovariectomized cynomolgus monkeys were treated with 0.1 or 0.3μg/day of ELD for 6months. This treatment increased lumbar BMD by 4.4% and 10.2%, respectively, and suppressed ovariectomy-induced increases in bone turnover markers compared to OVX-vehicle control. Histomorphometric analysis of bone revealed that both bone formation parameters and bone resorption parameters in the trabecular bone of the lumbar vertebrae were suppressed by ELD treatment. ELD treatment also improved biomechanical properties of the lumbar vertebrae and the femoral neck in the ovariectomized cynomolgus monkeys. These results indicate that, in a bone-remodeling animal model, ELD increases BMD and improves bone biomechanical properties by normalizing bone turnover. Therefore, ELD has a direct and potentially beneficial effect on bone metabolism.
<title>Embedding digital watermarks in halftone screens</title> (2000)

Invisible watermark images can be incorporated in printed halftone images using specially designed halftone screens. The watermark information is embedded into the image by varying the spatial correlation of the halftone texture. The halftone screen with embedded watermarks can be used exactly as a normal halftone screen, so there is no additional image processing required for processing individual images to embed watermarks. Once the binary output image is printed on the paper, the correlation of the binary image is converted into physical spatial correlation between neighboring areas of the printed image. This correlation relation is not visible to the eye but it can be detected by scanning the printed image on a desktop scanner and processing the scanned image. Printer and scanner distortions can interfere with the self-alignment of the scanned image, so localized adjustments are made to detect the embedded spatial correlation information in the watermarked image. The retrieval of this watermark is robust to copying and distortion and it can be detected in reproductions of the halftone image.
VEGF 165 Expressed by a Replication-Deficient Recombinant Adenovirus Vector Induces Angiogenesis In Vivo (1995)

To evaluate the concept that localized delivery of angiogenic factors via virus-mediated gene transfer may be useful in the treatment of ischemic disorders, the replication-deficient adenovirus (Ad) vector AdCMV.VEGF165 (where CMV is cytomegalovirus and VEGF is vascular endothelial growth factor) containing the cDNA for human VEGF165, a secreted endothelial cell-specific angiogenic growth factor, was constructed. Human umbilical vein endothelial cells (HUVECs) and rat aorta smooth muscle cells (RASMCs) infected with AdCMV.VEGF165 (5 and 20 plaque-forming units [pfu] per cell) demonstrated VEGF mRNA expression and protein secretion into the supernatant. Furthermore, the conditioned medium from these cells enhanced vascular permeability in vivo. In contrast, neither VEGF mRNA nor secreted protein was found in uninfected HUVECs or RASMCs or in cells infected with the control vector AdCMV.beta gal (where beta gal is beta-galactosidase). Assessment of starved HUVECs at 14 days demonstrated sixfold more cells for AdCMV.VEGF165-infected HUVECs (20 pfu per cell) than for either infected or uninfected control cells. RASMC proliferation was unaffected by infection with AdCMV.VEGF165. When plated in 2% serum on dishes precoated with reconstituted basement membrane (Matrigel), HUVECs infected with AdCMV.VEGF165 (20 pfu per cell) differentiated into capillary-like structures. Under similar conditions, both uninfected HUVECs and HUVECs infected with AdCMV.beta gal did not differentiate. To evaluate the ability of AdCMV.VEGF165 to function in vivo, either AdCMV. VEGF165 or AdCMV.beta gal (2 x 10(10) pfu) was resuspended in 0.5 mL Matrigel and injected subcutaneously into mice. Immunohistochemical staining demonstrated VEGF in the tissues surrounding the Matrigel plugs containing AdCMV.VEGF165 up to 3 weeks after injection, whereas no VEGF was found in the control plugs with AdCMV.beta gal. Two weeks after injection, there was histological evidence of neovascularization in the tissues surrounding the Matrigel containing AdCMV.VEGF165, whereas no significant angiogenesis was observed in response to AdCMV.beta gal. Furthermore, the Matrigel plugs with AdCMV.VEGF165 demonstrated hemoglobin content fourfold higher than the plugs with AdCMV.beta gal. Together, these in vitro and in vivo studies are consistent with the concept that Ad vectors may provide a useful strategy for efficient local delivery of VEGF165 in the treatment of ischemic diseases.
A Dose-Ranging Study of the Effects of Ethyl-Eicosapentaenoate in Patients With Ongoing Depression Despite Apparently Adequate Treatment With Standard Drugs (2002)

Treatment with ethyl-eicosapentaenoate at a dosage of 1 g/d was effective in treating depression in patients who remained depressed despite adequate standard therapy.
PathFinder: A Negotiation-Based Performance-Driven Router for FPGAs (1995)

Routing FPGAs is a challenging problem because of the relative scarcity of routing resources, both wires and connection points. This can lead either to slow implementations caused by long wiring paths that avoid congestion or a failure to route all signals. This paper presents PathFinder, a router that balances the goals of performance and routability. PathFinder uses an iterative algorithm that converges to a solution in which all signals are routed while achieving close to the optimal performance allowed by the placement. Routability is achieved by forcing signals to negotiate for a resource and thereby determine which signal needs the resource most. Delay is minimized by allowing the more critical signals a greater say in this negotiation. Because PathFinder requires only a directed graph to describe the architecture of routing resources, it adapts readily to a wide variety of FPGA architectures such as Triptych, Xilinx 3000 and mesh-connected arrays of FPGAs. The results of routing ISCAS benchmarks on the Triptych FPGA architecture show an average increase of only 4.5% in critical path delay over the optimum delay for a placement. Routes of ISCAS benchmarks on the Xilinx 3000 architecture show a greater completion rate than commercial tools, as well as 11% faster implementations.
ENZYME DISCOVERY HEATS UP (1996)

RETURN TO ISSUEPREVNewsNEXTENZYME DISCOVERY HEATS UPEnzymes that could maximize industrial processing reactions are reaped from exotic microorganismsMAIRIN B. BRENNANView Author Information C&EN WashingtonCite this: Chem. Eng. News 1996, 74, 42, 31–33Publication Date (Print):October 14, 1996Publication History Published online12 November 2010Published inissue 14 October 1996https://pubs.acs.org/doi/10.1021/cen-v074n042.p031https://doi.org/10.1021/cen-v074n042.p031newsACS PublicationsCopyright © 1996 AMERICAN CHEMICAL SOCIETYArticle Views5Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options SUBJECTS:Peptides and proteins Get e-Alerts
Cuticle damage and the tensile properties of human hair (1991)

Synopsis Oxidation of hair fibers with diperisophthalic acid can produce extensive damage throughout several cuticle layers that is readily observed microscopically. At the same time, no detectable changes in the tensile properties (wet or dry) are detectable. These results are consistent with the hypothesis that the tensile properties of human hair are due primarily to the cortex, with little or no cuticle involvement. human hair. There is a long-standing hypothesis, that the cortex is primarily responsible for the tensile properties of human hair (1), although there is one publication with limited data suggesting the possibility of some cuticle involvement in the tensile properties of hair (2) and some evidence that wool fibers containing a medulla are weaker than non- medullated fibers (3). If the cortex is primarily responsible for the tensile properties of hair fibers, or even if there be only minor cuticle and/or medullary involvement in the tensile properties of hair, then the tensile properties are primarily an index of cortical damage. Therefore, if the tensile properties do not show change, without any further experimental evidence, such data does not stand as an indication of no hair damage. The lack of cuticle involvement in the tensile properties of hair or even minimal in- volvement might seem surprising, because, for a 70-micron hair fiber with a 4-micron- thick band of cuticular material (2), the cuticle represents approximately 22% of the total fiber cross-sectional area. Thus, it would be somewhat surprising if the cuticle were not involved at all in the tensile properties of human hair. With respect to medullary involvement in the tensile properties of hair, such involve- ment has only been demonstrated for selected wool fibers where the medulla represented more than 70 percent of the cross section (3), and such heavy medullation is not common in human hair. A few years ago, we examined an oxidative treatment for hair based on diperisophthalic acid. We found that under certain conditions this reagent could produce extensive
Implications of the Changing Pattern of Bacterial Infections following Total Joint Replacements (2005)

This study found a definite increase in multiple-drug-resistant bacteria isolated from periprosthetic infections around total hip and knee prostheses.
Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling (2009)

Techniques for systematically monitoring protein translation have lagged far behind methods for measuring messenger RNA (mRNA) levels. Here, we present a ribosome-profiling strategy that is based on the deep sequencing of ribosome-protected mRNA fragments and enables genome-wide investigation of translation with subcodon resolution. We used this technique to monitor translation in budding yeast under both rich and starvation conditions. These studies defined the protein sequences being translated and found extensive translational control in both determining absolute protein abundance and responding to environmental stress. We also observed distinct phases during translation that involve a large decrease in ribosome density going from early to late peptide elongation as well as widespread regulated initiation at non-adenine-uracil-guanine (AUG) codons. Ribosome profiling is readily adaptable to other organisms, making high-precision investigation of protein translation experimentally accessible.
Oxcarbazepine (2002)

Oxcarbazepine is one of the recently introduced anti-epileptic drugs (AEDs) in the US. This drug has demonstrated efficacy as adjunctive therapy in adults and children, and as monotherapy in adults for the treatment of seizures of partial onset. There is also convincing evidence of its efficacy in patients with newly diagnosed and refractory trigeminal neuralgia. In addition, the initial efficacy results of oxcarbazepine in other neuropathic pain conditions and in bipolar disorders are encouraging. In this review, recommendations on the optimal clinical use of oxcarbazepine are given based on its pharmacokinetic profile, efficacy and tolerability in those various conditions.
Modeling Axonal Degeneration Within the Anterior Visual System (2008)

A major objective in multiple sclerosis therapeutics is to develop strategic targeting of specific injury pathways to provide neuroprotection and potentially even restoration. Here we underscore the potential utility of the anterior visual system for the purpose of modeling neuroprotection in response to novel therapies.
Finki at SemEval-2016 Task 4: Deep Learning Architecture for Twitter Sentiment Analysis (2016)

In this paper, we present a novel deep learning architecture for sentiment analysis in Twitter messages. Our system finki, employs both convolutional and gated recurrent neural networks to obtain a more diverse tweet representation. The network is trained on top of GloVe word embeddings pre-trained on the Common Crawl dataset. Both neural networks are used to obtain a fixed length representation of variable sized tweets, and the concatenation of these vectors is supplied to a fully connected softmax layer with dropout regularization. The system is evaluated on benchmark datasets from the Sentiment Analysis in Twitter task of the SemEval 2016 challenge where our model achieves best and second highest results on the 2-point and 5-point quantification subtasks respectively. Despite not relying on any hand-crafted features, our system manages the second highest average rank on the considered subtasks.
Therapeutic delivery opportunities, obstacles and applications for cell-penetrating peptides (2010)

Advancements in the development of large bioactive molecules as therapeutic agents have made drug delivery an active and important field of research. Cell-penetrating peptides (CPPs) have the ability to deliver an array of molecules and even nano-size particles into cells in an efficient and non-toxic manner, both in vitro and in vivo. This review aims to give a perspective on the obstacles that CPP-mediated drug delivery is currently facing as well as the great opportunities for improvements that lie ahead. Strategies for delivery of novel gene-modulating agents and enhancing efficacy of classical drugs will be discussed, as well as methods for increasing bioavailability and tissue specificity of CPPs. The usefulness and potential of CPPs as therapeutic drug-delivery vectors will be exemplified by their use in the treatment of cancer, viral infection and muscular dystrophy.
The Classification of Glomerulonephritis in Systemic Lupus Erythematosus Revisited (2004)

The currently used classification reflects our understanding of the pathogenesis of the various forms of lupus nephritis, but clinicopathologic studies have revealed the need for improved categorization and terminology. Based on the 1982 classification published under the auspices of the World Health Organization (WHO) and subsequent clinicopathologic data, we propose that class I and II be used for purely mesangial involvement (I, mesangial immune deposits without mesangial hypercellularity; II, mesangial immune deposits with mesangial hypercellularity); class III for focal glomerulonephritis (involving <50% of total number of glomeruli) with subdivisions for active and sclerotic lesions; class IV for diffuse glomerulonephritis (involving > or = 50% of total number of glomeruli) either with segmental (class IV-S) or global (class IV-G) involvement, and also with subdivisions for active and sclerotic lesions; class V for membranous lupus nephritis; and class VI for advanced sclerosing lesions]. Combinations of membranous and proliferative glomerulonephritis (i.e., class III and V or class IV and V) should be reported individually in the diagnostic line. The diagnosis should also include entries for any concomitant vascular or tubulointerstitial lesions. One of the main advantages of the current revised classification is that it provides a clear and unequivocal description of the various lesions and classes of lupus nephritis, allowing a better standardization and lending a basis for further clinicopathologic studies. We hope that this revision, which evolved under the auspices of the International Society of Nephrology and the Renal Pathology Society, will contribute to further advancement of the WHO classification.
A battery-free object localization and motion sensing platform (2014)

Indoor object localization can enable many ubicomp applications, such as asset tracking and object-related activity recognition. Most location and tracking systems rely on either battery-powered devices which create cost and maintenance issues or cameras which have accuracy and privacy issues. This paper introduces a system that is able to detect the 3D position and motion of a battery-free RFID tag embedded with an ultrasound detector and an accelerometer. Combining tags' acceleration with location improves the system's power management and supports activity recognition. We characterize the system's localization performance in open space as well as implement it in a smart wet lab application. The system is used to track real-time location and motion of the tags in the wet lab as well as recognize pouring actions performed on the objects to which the tag is attached. The median localization accuracy is 7.6cm -- (3.1, 5, 1.9)cm for each (x, y, z) axis -- with max update rates of 15 Sample/s using single RFID reader antenna.