gebhart/patrepeval huggingface dataset:
AUTONOMOUS MOBILE ROBOT WITH HYBRID PEM FUEL-CELL AND ULTRACAPACITORS ENERGY SYSTEM. DEDALO 2.0 (2017)

This paper presents a hybrid configuration combining a hydrogen fuel cell and ultracapacitors to create an energy storage system. Hybrid topology is constructed using a SEPIC converter, which connects the fuel cell with the DC bus whereas a bidirectional Buck-Boost converter links the ultracapacitors group with the DC bus. The main aim is to increase the efficiency of the hybrid power system applied about an autonomous mobile robot. An active Fuel Cell voltage control strategy is presented to manage the power flows. In addition, the overall efficiency of the proposed hybrid power system at overload operation is higher than the conventional one. In this paper, an autonomous mobile robot was converted from a conventional lead-acid or lithium-ion battery to a hybrid PEM Fuel-Cell and ultracapacitors as the power source. The integration of UCaps as element of energy storage on the robot was studied with the aim to improve the energetic solution
ChemInform Abstract: Synthesis of Diarylsulfides and Diarylsulfones Containing Pyrazoline, Isoxazoline, Pyrimidine and Condensed Pyridazine Moieties. (1992)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Spectrographic Study of Vowel Reduction (1963)

Measurements of formant frequencies and duration are reported for 8 Swedish vowels uttered by a male talker in three consonantal environments under varying timing conditions. An exponential function is used to describe the extent to which formant frequencies in the vowels reach their target values as a function of vowel-segment duration. A target is specified by the asymptotic values of the first two formant frequencies of the vowel and is independent of consonantal context and duration. It is thus an invariant attribute of the vowel. The results suggest an interpretation in terms of a simple dynamic model of vowel articulation.
Olefin Metatheses and Related Reactions Initiated by Carbene Derivatives of Metals in Low Oxidation States (2005)

Experiments carried out 24 years ago with tantalum carbenes have led to the much cited hypothesis that metals (other than ruthenium) must be in their highest oxidation states for their carbene derivatives to initiate olefin metatheses. The hypothesis legitimizes the uniqueness of high-oxidation-state molybdenum and tungsten carbenes as effective initiators, and it means that the Fischer tungsten carbenes that even earlier were found to initiate olefin metatheses and related transformations must be oxidized before they can be effective. The newer initiators have been termed "well-defined", the older "ill-defined". But what does the evidence show?
Expression of liver‐specific genes coding for plasma proteins in protein deficiency (1989)

Protein deficiency leads to a decreased concentration of plasma proteins, although it is not clear whether this response is caused by alterations in gene transcription or in post‐transcriptional events. The aim of this study was to investigate the expression of some liver‐specific genes coding for plasma proteins in rats kept on a protein‐free diet for 30 days. Cloned cDNA probes for the albumin, transthyretin, retinol‐binding protein and prothrombin genes were used in Northern hybridizations to total liver RNA to compare their transcript levels in protein‐deficient and control animals. Liver polysomes were also isolated and fractionated from the two groups of animals to examine the possible effects of protein deficiency on translation of the mRNAs. The results indicate that the albumin and transthyretin mRNAs are present in lower amounts in protein deficiency. The distribution profile along sucrose gradients shows that all mRNAs are undergoing translation, but in protein‐deficient animals a small but consistent fraction of each mRNA is also present in the non‐polysomal, low molecular weight fractions.
Testosterone gel for the treatment of male hypogonadism (2008)

Testosterone gel has proved to be a valuable contribution to the existing modes of testosterone treatment, combining therapeutic efficacy, convenience and safety.
Human Milk Supplementation (1988)

Human milk when fed to preterm infants is frequently supplemented with human milk fortifiers that provide an additional source of protein, energy, and minerals. Human milk that was provided by the mother of a preterm infant, and that was supplemented with commercially available human milk fortifiers, was assessed under simulated syringe-pump and bolus feeding circumstances for the delivery of energy, calcium, phosphorus, copper, magnesium, and zinc to an infant. In general, the nutrients were not completely delivered with syringe-pump feedings, with the greatest losses occurring in the concentrations of calcium and phosphorus. The losses were more pronounced with the use of a powdered fortifier than with the use of a liquid fortifier. Little or no change in the concentrations of the various nutrients were observed with simulated bolus feeding. We suggest that human milk fortified with supplements be fed with care to assure complete delivery of the nutrients and that infants receiving such feedings be monitored to assure adequate nutritional status.
Full-field optical coherence microscopy (1998)

We present a new microscopy system for imaging in turbid media that is based on the spatial coherence gate principle and generates in parallel a complete two-dimensional head-on image without scanning. This system has been implemented in a commercial microscope and preserves the lateral resolution of the optics used. With a spatially incoherent source, speckle-free images with diffraction-limited resolution are recorded at successive depths with shot-noise-limited detection. The setup comprises a photoelastic modulator for path difference modulation and a two-dimensional CCD array and uses a multiplexed lock-in detection scheme.
50 nm Polystyrene Particles via Miniemulsion Polymerization (2001)

ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXT50 nm Polystyrene Particles via Miniemulsion PolymerizationChristopher D. Anderson, E. David Sudol, and Mohamed S. El-AasserView Author Information Emulsion Polymers Institute, Department of Chemical Engineering, Lehigh University, Bethlehem, Pennsylvania 18015 Cite this: Macromolecules 2002, 35, 2, 574–576Publication Date (Web):December 18, 2001Publication History Received9 February 2001Revised16 October 2001Published online18 December 2001Published inissue 1 January 2002https://pubs.acs.org/doi/10.1021/ma010242zhttps://doi.org/10.1021/ma010242zbrief-reportACS PublicationsCopyright © 2002 American Chemical SocietyRequest reuse permissionsArticle Views1303Altmetric-Citations53LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Emulsions,Liquids,Nucleation,Polymer particles,Surfactants Get e-Alerts
A Polarization Control System for Satellite Communications with Multiple Uplinks (1978)

Several groups have designed polarization control systems to solve the rain-crosspolarization problem in satellite communications. However, the multiple-uplink problem still exists, i.e., one system cannot receive signals from different uplink stations with different rain conditions simultaneously. In order to solve this problem, a new scheme is developed in this paper based on the assumption that an obtainable correlation exists between the uplink and downlink crosspolarizations and the concept that uplink and downlink can be compensated separately. The currently designed systems can be used directly in this scheme; only the addition of similar devices is necessary. The feasibility is checked by a practical example, and satisfactory performance is observed.
OC30.08: Stage‐related outcome in severe mid‐trimester twin–twin transfusion syndrome treated by fetoscopic laser coagulation (2005)

To assess perinatal outcome in monochorionic diamniotic twin pregnancies with different stages of severe mid-trimester twin–twin transfusion syndrome (TTTS) managed by fetoscopic laser coagulation of the placental vascular anastomoses. In a prospective study fetoscopic laser therapy was performed in 200 consecutive pregnancies with severe mid-trimester TTTS between 16 and 26 weeks of gestation; outcome data was analysed for the whole group and separately for stage I (n = 29), stage II (n = 81), stage III (n = 80) and stage IV (n = 10) according to the Quintero staging system. The overall survival rate for all 200 pregnancies was 71% (284/400), with survival of both twins in 59% (118/200) and survival of ≥ 1 twin in 83% (166/200). The median gestational age at delivery of liveborn babies was 34.3 weeks (range 23.1–40.4). Overall survival rates were 84.5% for stage I (49/58), 71% for stage II (115/162), 67.5% for stage III (108/160) and 60% for stage IV (12/20); The percentage of pregnancies with survival of both fetuses was 75.9% for stage I (22/29), 59.3% for stage II (48/81), 53.8% for stage III (43/80) and 50% for stage IV (5/10). At least one of the twins survived in 93.1% in group I (27/29), 82.7% in group II (67/81), 81.3% in group III (65/80) and 70% in group IV (7/10). These data show that laser therapy is the most effective therapeutic option also in advanced stages of TTTS and provide information to counsel patients more detailed according to the stage of syndrome.
Inflammatory Corneal Neovascularization: Etiopathogenesis (2011)

There is a delicate balance between pro-angiogenic stimuli and anti-angiogenic stimuli in the normal cornea. This balance allows the cornea to normally exist in a relatively avascular state, which is needed for optical clarity and vision. However, in the setting of inflammation, this balance may be shifted in favor of neovascularization. This paper reviews the literature on corneal inflammatory neovascularization beginning with the pro-angiogenic factors, such as Vascular Endothelial Growth Factor and Fibroblast Growth Factor, which help to facilitate the development of new corneal vessels. Subsequently the anti-angiogenic factors and their role in preventing neovascularization in the normal cornea are reviewed. Finally, a review of several etiologies of inflammatory neovascularization is presented with attention to the processes that allow the pro-angiogenic stimuli to overwhelm the anti-angiogenic factors.
Microlithographic process for patterning conjugated emissive polymers (1997)

The spatially confined synthesis of emissive conjugated polymers —compatible with existing 1C fabrication technology—is described, which can be used to create well‐defined micrometerscale patterned organic LEDs (see cover). The Figure shows the first step in the photolithographic process, which is followed by irradication, to produce a latent image, and development, resulting in patterned polymer. magnified image
Image feature analysis and computer‐aided diagnosis in digital radiography: Automated delineation of posterior ribs in chest images (1991)

In order to facilitate computerized quantitative analysis of digital chest radiographs, an automated method for accurate delineation of posterior ribs in frontal chest images is being developed. This method is based on an analysis of vertical profiles in the lung regions and a statistical analysis of edge gradients and their orientations in small selected regions-of-interest (ROIs). A shift-variant function is fitted to vertical profiles to obtain initial estimates of locations of rib edges. Rib edges are then determined more accurately by analyzing cumulative edge gradients and their orientations in small ROIs that are located adjacent to the initially estimated edges. The present computerized method can achieve a good agreement between the detected and the actual rib structures for posterior ribs in 74% of 50 cases examined. This suggests that automated detection of posterior ribs by a computerized method is feasible, and may be useful for computer-aided diagnostic schemes in the chest.
Vertical-cavity surface-emitting lasers come of age (1996)

This manuscript reviews our efforts in demonstrating state-of-the-art planar, batch-fabricable, high-performance vertical-cavity surface-emitting lasers (VCSELs). All performance requirements for short-haul data communication applications are clearly established. We concentrate on the flexibility of the established proton-implanted AlGaAs-based (emitting near 850 nm) technology platform, focusing on a standard device design. This structure is shown to meet or exceed performance and producibility requirements. These include &gt; 99% device yield across 3-in-dia. metal-organic vapor phase epitaxy (MOVPE)-grown wafers and wavelength operation across a &gt; 100-nm range. Recent progress in device performance [low threshold voltage (V<SUB>th</SUB> equals 1.53 V); threshold current (I<SUB>th</SUB> equals 0.68 mA); continuous wave (CW) power (P<SUB>cw</SUB> equals 59 mW); maximum and minimum CW lasing temperature (T equals 200 degree(s)C, 10 K); and wall-plug efficiencies ((eta) <SUB>wp</SUB> equals 28%)] should enable great advances in VCSEL-based technologies. We also discuss the viability of VCSELs in cryogenic and avionic/military environments. Also reviewed is a novel technique, modifying this established platform, to engineer low-threshold, high-speed, single- mode VCSELs.
Wound healing - A literature review (2016)

Regeneration and tissue repair processes consist of a sequence of molecular and cellular events which occur after the onset of a tissue lesion in order to restore the damaged tissue. The exsudative, proliferative, and extracellular matrix remodeling phases are sequential events that occur through the integration of dynamic processes involving soluble mediators, blood cells, and parenchymal cells. Exsudative phenomena that take place after injury contribute to the development of tissue edema. The proliferative stage seeks to reduce the area of tissue injury by contracting myofibroblasts and fibroplasia. At this stage, angiogenesis and reepithelialization processes can still be observed. Endothelial cells are able to differentiate into mesenchymal components, and this difference appears to be finely orchestrated by a set of signaling proteins that have been studied in the literature. This pathway is known as Hedgehog. The purpose of this review is to describe the various cellular and molecular aspects involved in the skin healing process.
Prenatal diagnosis of carbamoyl phosphate synthetase I deficiency by identification of a missense mutation in CPS1 (1998)

Carbamoyl phosphate synthetase I (CPS1) deficiency is an autosomal recessive metabolic disorder affecting the first enzymatic step of urea cycle. We report a consanguineous family in which the index patient died at 11 days of age from a severe form of CPS1 deficiency. Initial diagnosis was based on clinical histopathological, and enzymatic investigations. Direct sequencing of the complete CPS1 coding region revealed a disease-associated homozygous Thr544Met mutation in CPS1. On the basis of the molecular data, prenatal diagnosis was established for genomic DNA and performed at gestational week 12, after chorionic villus sampling. The fetus was homozygous for the Thr544Met mutation, and termination of pregnancy was elected. Histopathological signs of the hepatocellular metabolic disorder similar to that of the index patient were found in fetal liver thus giving morphological evidence for this hereditary error of urea cycle function as early as gestational week 12. Hum Mutat 12:206–211, 1998. © 1998 Wiley-Liss, Inc.
Roles of Glu 349 and Asp 352 in membrane insertion and translocation by diphtheria toxin (1996)

Acidic conditions within the endosomal lumen induce the T domain of receptor-bound diphtheria toxin (DT) to insert into the endosomal membrane and mediate translocation of the toxin's catalytic domain to the cytosol. A conformational rearrangement in the toxin occurring near pH5 allows a buried apolar helical hairpin of the native T domain (helices TH8 and TH9) to undergo membrane insertion. If the inserted hairpin spans the bilayer, as hypothesized, then the two acidic residues within the TL5 interhelical loop, Glu 349 and Asp 352, should become exposed at the neutral cytosolic face of the membrane and reionize. To investigate the roles of these residues in toxin action, we characterized mutant toxins in which one or both acidic residues had been replaced with nonionizable ones. Each of two double mutants examined showed a several-fold reduction in cytotoxicity in 24-h Vero cell assays (sixfold for E349A + D352A and fourfold for E349Q + D352N), whereas the individual E349Q and D352N mutations caused smaller reductions in toxicity. The single and double mutations also attenuated the toxin's ability to permeabilize Vero cells to Rb+ at low pH and decreased channel formation by the toxin in artificial planar bilayers. Neither of the double mutations affected the pH-dependence profile of the toxin's conformational rearrangement in solution, as measured by binding of the hydrophobic fluorophore, 2-p-toluidinyl-naphthalene 6-sulfonate. The results demonstrate that, although there is no absolute requirement for an acidic residue within the TL5 loop for toxicity, Glu 349 and Asp 352 do significantly enhance the biological activity of the protein. The data are consistent with a model in which ionization of these residues at the cytosolic face of the endosomal membrane stabilizes the TH8/TH9 hairpin in a transmembrane configuration, thereby facilitating channel formation and translocation of the toxin's catalytic chain.
Controlled gene expression systems for lactic acid bacteria: transferable nisin-inducible expression cassettes for Lactococcus, Leuconostoc, and Lactobacillus spp (1997)

A transferable dual-plasmid inducible gene expression system for use in lactic acid bacteria that is based on the autoregulatory properties of the antimicrobial peptide nisin produced by Lactococcus lactis was developed. Introduction of the two plasmids allowed nisin-inducible gene expression in Lactococcus lactis MG1363, Leuconostoc lactis NZ6091, and Lactobacillus helveticus CNRZ32. Typically, the beta-glucuronidase activity (used as a reporter in this study) remained below the detection limits under noninducing conditions and could be raised to high levels, by addition of subinhibitory amounts of nisin to the growth medium, while exhibiting a linear dose-response relationship. These results demonstrate that the nisin-inducible system can be functionally implemented in lactic acid bacteria other than Lactococcus lactis.
Inhibitors of Vascular Endothelial Growth Factor in Cancer (2008)

Angiogenesis is a complex process that is regulated by pro- and antiangiogenic factors. These factors can emanate from diverse sources including cancer cells, stromal cells, blood and extracellular matrix. Their relative contribution is likely to change with tumor type and tumor site. Vascular endothelial growth factor (VEGF) is now well confirmed as the primary and the most potent inducer of angiogenesis. To activate cellular signaling pathways, VEGF binds to receptor kinases VEGF-R1, R2 and R3. It then promotes several events required for the formation of new blood vessels, such as endothelial cell survival, proliferation, migration and vascular permeability. Activation of endothelial cells, leads to the secretion of enzymes which degrade the extracellular matrix (ECM) and hence promote metastasis. Similarly it promotes survival by inducing Bcl-2 expression on VEGF receptor positive leukemia. Besides being a potent mitogen for macrovascular cells derived from arteries, veins and lymphatics, it is also highly involved in a number of angiogenic related disorders including inflammatory diseases, rheumatoid arthritis, psoriasis, retinopathies and age related macular degeneration. Neovascularization and increased vessel permeability are being recognized as major causes of VEGF related pathogenesis. Therefore, inhibition of VEGF pathway is a strategy being widely pursued to provide new therapeutics for the treatment of VEGF related disorders. Over twenty compounds with anti-angiogenic properties ranging from VEGF neutralizing antibody, soluble receptors, receptor antagonists or tyrosine kinase inhibitors (TKIs) are either approved or are currently under clinical (phase I - III) study. This review aims to provide an updated account of how VEGF inhibitors are shaping up to become an important class of drugs used in the treatment of cancer.
The bioequivalence of frozen plasma prepared from whole blood held overnight at room temperature compared to fresh‐frozen plasma prepared within eight hours of collection (2014)

Leukoreduced FFP and PF24RT24WB prepared using the LEUKOSEP HWB-600-XL system has been shown to be BE to control leukoreduced FFP with an expected decrease in FVIII activity after overnight hold.