gebhart/patrepeval huggingface dataset:
Clustering with Multiple Graphs (2009)

In graph-based learning models, entities are often represented as vertices in an undirected graph with weighted edges describing the relationships between entities. In many real-world applications, however, entities are often associated with relations of different types and/or from different sources, which can be well captured by multiple undirected graphs over the same set of vertices. How to exploit such multiple sources of information to make better inferences on entities remains an interesting open problem. In this paper, we focus on the problem of clustering the vertices based on multiple graphs in both unsupervised and semi-supervised settings. As one of our contributions, we propose Linked Matrix Factorization (LMF) as a novel way of fusing information from multiple graph sources. In LMF, each graph is approximated by matrix factorization with a graph-specific factor and a factor common to all graphs, where the common factor provides features for all vertices. Experiments on SIAM journal data show that (1) we can improve the clustering accuracy through fusing multiple sources of information with several models, and (2) LMF yields superior or competitive results compared to other graph-based clustering methods.
Myopic Intrastromal Photorefractive Keratectomy With the Neodymium-Yttrium Lithium Fluoride Picosecond Laser in the Cat Cornea (1995)

Intrastromal PRK with the Nd-YLF picosecond laser produces central flattening of the cat cornea with barely perceptible stromal haze and no regression of topographic effect after 6 months in the absence of treatment with anti-inflammatory agents.
Transcranial magnetic stimulation (TMS) inhibits cortical dendrites (2016)

One of the leading approaches to non-invasively treat a variety of brain disorders is transcranial magnetic stimulation (TMS). However, despite its clinical prevalence, very little is known about the action of TMS at the cellular level let alone what effect it might have at the subcellular level (e.g. dendrites). Here, we examine the effect of single-pulse TMS on dendritic activity in layer 5 pyramidal neurons of the somatosensory cortex using an optical fiber imaging approach. We find that TMS causes GABAB-mediated inhibition of sensory-evoked dendritic Ca(2+) activity. We conclude that TMS directly activates fibers within the upper cortical layers that leads to the activation of dendrite-targeting inhibitory neurons which in turn suppress dendritic Ca(2+) activity. This result implies a specificity of TMS at the dendritic level that could in principle be exploited for investigating these structures non-invasively.
Triceps Split Technique for Total Elbow Arthroplasty (2002)

Exposure for total elbow arthroplasty can be challenging. Various different approaches that have been described have advantages and disadvantages. The triceps split technique offers several advantages over other common approaches to elbow arthroplasty with respect to maintenance of the soft tissue envelope, the sequential ability to release collateral ligaments, and the ability to extend the approach both proximally and distally. The author's experience with the triceps split technique for total elbow arthroplasty has been an addition to his armamentarium in approaching the elbow and now is his preferred method to approach most cases treated with total elbow arthroplasty.
Dispersion Behavior of Barium Titanate Nanoparticles Prepared by Using Various Polycarboxylic Dispersants (2007)

The effects of the polycarboxylic dispersant structures on the crystallinity and sedimentation behavior of prepared BaTiO 3 nanoparticles were analyzed using four types of dispersants—ethylenediaminetetraacetic acid dipotassium salt (EDTA), trans ‐aconitic acid (TAA), ammonium acrylate–methyl acrylate co‐polymer (PAA50), and sodium polyacrylate (PAA100). In the case of EDTA and TAA, the adsorbed ratio of the dispersants on BaTiO 3 nanoparticles was relatively low, and only slight improvement of sedimentation behavior was observed. On the other hand, in the case of PAA50 and PAA100, the adsorbed ratio was high, and the sedimentation behavior was gratefully improved. Next, in order to analyze the relationships among the additive amount of polycarboxylic dispersants, crystallinity, and sedimentation behavior, various amounts of PAA100 or PAA50 were treated in the synthesis solution. The sedimentation behavior of BaTiO 3 nanoparticles improved with increasing amounts of PAA100 and PAA50 while their crystal phase became amorphous. Adding PAA50 at a molar ratio of COO − /Ba 2+ =0.266 resulted in BaTiO 3 nanoparticles with the best dispersion stability in an aqueous media.
Evidence for the Use of Activated Prothrombin Complex Concentrates (aPCCs) in the Treatment of Patients with Haemophilia and Inhibitors (2002)

FEIBA and Autoplex T have been used to control bleeding in patients with factor VIII or IX inhibitors for over 25 years. The major components of FEIBA are thought to be activated factor X and prothrombin, whereas the main active components in Autoplex T are thought to be activated factors IX and VII. Both products have been found to effectively control approximately 80% of bleeds involving joints and soft tissues. Published experience of their use in surgery is limited. Thrombotic complications have been reported with high dose FEIBA therapy and have led to maximum dosage guidelines for this product.
SfM with MRFs: Discrete-Continuous Optimization for Large-Scale Structure from Motion (2012)

Recent work in structure from motion (SfM) has built 3D models from large collections of images downloaded from the Internet. Many approaches to this problem use incremental algorithms that solve progressively larger bundle adjustment problems. These incremental techniques scale poorly as the image collection grows, and can suffer from drift or local minima. We present an alternative framework for SfM based on finding a coarse initial solution using hybrid discrete-continuous optimization and then improving that solution using bundle adjustment. The initial optimization step uses a discrete Markov random field (MRF) formulation, coupled with a continuous Levenberg-Marquardt refinement. The formulation naturally incorporates various sources of information about both the cameras and points, including noisy geotags and vanishing point (VP) estimates. We test our method on several large-scale photo collections, including one with measured camera positions, and show that it produces models that are similar to or better than those produced by incremental bundle adjustment, but more robustly and in a fraction of the time.
Different approaches (1992)

Examines various approaches to implementing TQM in the service industry, specifically within the Avon Training and Enterprise Council. Explains how management commitment to TQM can be achieved and maintained in service organizations. Details the key differences and similarities between service and manufacturing organizations. Outlines different methods of measuring TQM progress in the organization.
Human immunodeficiency virus type 1 envelope glycoprotein oligomerization requires the gp41 amphipathic alpha-helical/leucine zipper-like sequence (1997)

Human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein (Env) oligomerization was investigated by coexpressing wild-type and truncated envelope glycoproteins to determine the minimum sequence required for mutant-wild-type hetero-oligomerization. The gp41 putative amphipathic alpha-helix, Leu-550 to Leu-582, was essential for hetero-oligomer formation. Alanine substitution of 9 of the 10 residues composing the gp41 amphipathic alpha-helix 4-3 hydrophobic repeat sequence was required to inhibit mutant-wild-type hetero-oligomerization and to render the envelope glycoprotein precursor, gp160, monomeric. This indicates that multiple hydrophobic contacts contribute to the stable envelope glycoprotein oligomeric structure. Single alanine substitutions within the hydrophobic repeat sequence did not affect gp160 oligomeric structure but abolished syncytium-forming function. Some mutations also diminished gp160 processing efficiency and the association between gp120 and gp41 in a position-dependent manner. These results indicate that the gp41 amphipathic alpha-helix 4-3 hydrophobic repeat sequence plays a central role in HIV-1 envelope glycoprotein oligomerization and fusion function.
Optical sensing system based on wireless paired emitter detector diode device and ionogels for lab-on-a-disc water quality analysis (2012)

This work describes the first use of a wireless paired emitter detector diode device (PEDD) as an optical sensor for water quality monitoring in a lab-on-a-disc device. The microfluidic platform, based on an ionogel sensing area combined with a low-cost optical sensor, is applied for quantitative pH and qualitative turbidity monitoring of water samples at point-of-need. The autonomous capabilities of the PEDD system, combined with the portability and wireless communication of the full device, provide the flexibility needed for on-site water testing. Water samples from local fresh and brackish sources were successfully analysed using the device, showing very good correlation with standard bench-top systems.
Cellular adaptation to amino acid availability : mechanisms involved in the regulation of gene expression (2006)

Bien que l’étude du rôle des nutriments dans la régulation de l’expression des gènes chez les Mammifères soit devenue un domaine de recherche important, les mécanismes impliquant les acides aminés sont encore peu connus. Du fait de l’importance de leurs rôles physiologiques, l’homéostasie des acides aminés doit être finement régulée. Cependant, les concentrations plasmatiques des acides aminés peuvent être affectées par certaines conditions nutritionnelles ou différentes formes d’agression. En régulant l’expression d’un grand nombre de gènes, l’organisme a la capacité d’ajuster certaines de ses fonctions impliquées dans l’adaptation à la disponibilité en acides aminés. Cette revue vise à rassembler les données actuelles concernant le rôle des acides aminés dans la régulation de l’expression des gènes et des fonctions physiologiques chez les Mammifères. Pour plusieurs acides aminés dits «indispensables » , une diminution de leur concentration entraîne la stimulation de l’expression de gènes cibles spécifiques tels que les gènes codant pour IGFBP-1, CHOP et l’asparagine synthétase (AS). Les mécanismes moléculaires impliqués dans l’activation transcriptionnelle de CHOP et AS en réponse à une carence en acide aminé ont été en partie identifiés. En particulier, une voie de signalisation faisant intervenir la protéine kinase GCN2 et le facteur de transcription ATF4 joue le rôle de senseur des déficits en acides aminés. Au niveau physiologique, des travaux récents montrent que l’activation de cette voie permet, par le biais d’un circuit neuronal, d’inhiber la prise alimentaire lorsque l’apport nutritionnel en acides aminés est déséquilibré. L’ensemble des données présentées dans cette revue montre que les acides aminés peuvent agir comme des molécules «signal » contrôlant l’expression de gènes afin de réguler certaines fonctions physiologiques.
Controlling The Code (2012)

RETURN TO ISSUEPREVNewsNEXTControlling The CodeView Author Information C&EN Northeast News BureauCite this: Chem. Eng. News 2012, 90, 16, 12–19Publication Date (Print):April 16, 2012Publication History Published online29 March 2013Published inissue 16 April 2012https://pubs.acs.org/doi/10.1021/cen-09016-cover1https://doi.org/10.1021/cen-09016-cover1newsACS PublicationsCopyright © 2012 Chemical & Engineering NewsArticle Views16Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options SUBJECTS:Genetics Get e-Alerts
Size-Controlled Synthesis of Magnetite Nanoparticles (2002)

Monodisperse magnetite nanoparticles have been synthesized by high-temperature solution-phase reaction of Fe(acac)3 in phenyl ether with alcohol, oleic acid, and oleylamine. Seed-mediated growth is used to control Fe3O4 nanoparticle size, and variously sized nanoparticles from 3 to 20 nm have been produced. The as-synthesized Fe3O4 nanoparticles have inverse spinel structure, and their assemblies can be transformed into gamma-Fe2O3 or alpha-Fe nanoparticle assemblies, depending on the annealing conditions. The reported procedure can be used as a general approach to various ferrite nanoparticles and nanoparticle superlattices.
Das Anti-Jo-1-Syndrom – eine Sonderform der Myositis mit interstitieller Lungenerkrankung (2010)

Interstitial lung disease (ILD) may be associated with systemic inflammatory disorders and autoantibody production. The development of ILD has been described in detail in patients with polymyositis and dermatomyositis. Anti-synthetase antibodies, including anti-Jo-1 antibodies (antihistidyl-tRNA syntase), are found in up to 35 % of patients with myositis, 80 % of which constitute anti-Jo-1 antibodies. The anti-Jo-1 syndrome characteristically presents with myositis, shortness of breath, fever, polyarthritis/arthralgia, mechanic's hands, dermatomyositis-like skin lesions, signs of a connective tissue disease and/or Raynaud's phenomenon. ILD is an early diagnostic sign and shows focal infiltrates and an acinar pattern in CT scan. Non-specific interstitial pneumonitis with T-lymphocytic infiltrates in lung histology (VATS) or elevated IFN-gamma-inducible chemokines are further indicators for anti-Jo-1 syndrome. Corticosteroids eventually combined with an immunosuppressant drug are often required with reported beneficial effects, although not many therapeutic studies have been performed. Here we present a review of the current literature and a case report on anti-Jo-1 syndrome.
Production of Polyhydric Alcohols from Wood Polysaccharides (1963)

Abstract By hydrolysis and hydrogenolysis, plant polysaccharides, i.e. mainly cellulose and hemicelluloses, can be converted with high yields into polyhydric alcohols (hexitols, pentitols, glycerol, ethylene glycol, propylene glycol). Procedures which have been developed in the U.S.S.R. are described. Of particular interest is the simultaneous hydrolysis and hydrogenolysis of plant polysaccharides with noble metal catalysts. Here yields are almost quantitative.
Preparation of Macroporous Metal Films from Colloidal Crystals (1999)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTPreparation of Macroporous Metal Films from Colloidal CrystalsPeng Jiang, Joel Cizeron, Jane F. Bertone, and Vicki L. ColvinView Author Information Department of Chemistry, Rice University Houston, Texas 77005 Cite this: J. Am. Chem. Soc. 1999, 121, 34, 7957–7958Publication Date (Web):August 13, 1999Publication History Received26 April 1999Published online13 August 1999Published inissue 1 September 1999https://pubs.acs.org/doi/10.1021/ja991321hhttps://doi.org/10.1021/ja991321hrapid-communicationACS PublicationsCopyright © 1999 American Chemical SocietyRequest reuse permissionsArticle Views2644Altmetric-Citations317LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Crystals,Deposition,Genetics,Metals,Silica Get e-Alerts
Sources of Variability in Rat Caries Studies: Weaning Age and Diet Fed During Tooth Eruption (1977)

A factorial design (2x2) was used to study the caries effect of two diets (starch based versus stock) fed to rat dams and their litters, and also of variations in the weaning age (19 versus 25 days). Higher and reproducible caries scores were obtained in rats which were fed a purified starch-based diet, weaned at 19 days of age, and subsequently given a cariogenic challenge.
Bereitschaft (readiness potential) and supplemental motor area interaction in movement generation: spinal cord injury and normal subjects. (2004)

The readiness potential (BP) consists of movement-related cortical potentials (MRCPs) peaking in the motor potential (MP). Our objective was to better understand the role of the BP and MP in the production of voluntary movements and to help define the relative roles of the supplementary motor area (SMA) and the BP in the generation of self-paced and passive finger movements. The ultimate goal was to relate the BP (or the SMA) to external devices via conversion of potentials to a language "understood" by the receiving devices.
Pharmacodynamic and pharmacokinetic study of chronic low-dose metronomic cyclophosphamide therapy in mice (2007)

Prolonged, frequently administered low-dose metronomic chemotherapy (LDM) is being explored (pre)clinically as a promising antiangiogenic antitumor strategy. Although appealing because of a favorable side effect profile and mostly oral dosing, LDM involves new challenges different from conventional maximum tolerated dose chemotherapy. These include possible altered pharmacokinetic characteristics due to long-term drug exposure potentially resulting in acquired resistance and increased risk of unfavorable drug interactions. We therefore compared the antitumor and antivascular effects of LDM cyclophosphamide (CPA) given to mice that had been pretreated with either LDM CPA or normal saline, obtained blood 4-hydroxy-CPA (activated CPA) concentrations using either gas chromatography/mass spectrometry or liquid chromatography/tandem mass spectrometry in mice treated with LDM CPA, and measured hepatic and intratumoral activity of enzymes involved in the biotransformation of CPA and many other drugs [i.e., cytochrome P450 3A4 (CYP3A4) and aldehyde dehydrogenase]. Exposure of mice to LDM CPA for >or=8 weeks did not compromise subsequent activity of LDM CPA therapy, and biologically active 4-hydroxy-CPA levels were maintained during long-term LDM CPA administration. Whereas the effects on CYP3A4 were complex, aldehyde dehydrogenase activity was not affected. In summary, our findings suggest that acquired resistance to LDM CPA is unlikely accounted for by altered CPA biotransformation. In the absence of reliable pharmacodynamic surrogate markers, pharmacokinetic parameters might become helpful to individualize/optimize LDM CPA therapy. LDM CPA-associated changes of CYP3A4 activity point to a potential risk of unfavorable drug interactions when compounds that are metabolized by CYP3A4 are coadministered with LDM CPA.
ANIMAL VIRUS DNA REPLICATION (1989)

The Hippo pathway was initially discovered in Drosophila melanogaster as a key regulator of tissue growth. It is an evolutionarily conserved signaling cascade regulating numerous biological processes, including cell growth and fate decision, organ size ...Read More
Surface-machined micromechanical membrane pump (2002)

An electrostatic micromechanical membrane pump for fluids and gases has been designed and fabricated with a process that is compatible with integrated circuits. The process consists of six photolithography steps and eight low-pressure chemical vapor depositions. No bulk silicon etchants or wafer bonding techniques are used. Each pump consists of an input valve, a pumping membrane, and an output valve. All parts are encapsulated by silicon nitride and are actuated by electrostatic forces. Actuation voltages of approximately 50 V are required for observable valve closure and membrane deflections. Typical gas pumping displacements are between 12 to 640 nL per cycle.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Calibration and 3-D sound reproduction in the Immersive Audio Environment (2011)

The effectiveness of virtual environments depends largely on how efficiently they recreate the real world. In the case of auditory virtual environments, the importance of accurate recreation is enhanced since there are no visual cues to assist perception, as in the case of audio-visual virtual environments. In this paper, we present the Immersive Audio Environment (IAE), an easily constructible and portable structure, which is capable of 3-D sound auralization with very high spatial resolution. A novel method for acoustically positioning loudspeakers in space, which is required by the IAE for simulation of sound sources, is presented in this paper. Our contribution is the creation of a system that uses existing and modifications of existing techniques such as Vector Based Amplitude Panning (VBAP) in order to recreate an audio battle environment. The IAE recreates the audio effects of battle scenes and can be used as a virtual battle environment for the training of soldiers. It can also easily be used in other areas such as commercial entertainment.
A Technique for Faster Pulse-Decay Permeability Measurements in Tight Rocks (1997)

Summary Laboratory pulse-decay measurements using a gas or liquid are effective for determining the permeability of rocks in the range from 0.1 md to 0.01 μd. The actual measurement time with this pressure-transient technique is fairly short, but pressure pre-equilibration sometimes requires hours. This paper shows how the total time can be reduced significantly, especially if the sample's pore volume (PV) is measured independently or estimated accurately. Permeability is calculated from "late-time" measurements. Strategies for minimizing errors and increasing sample throughput are presented.