gebhart/patrepeval huggingface dataset:
Cu Mesh for Flexible Transparent Conductive Electrodes (2015)

Copper electrodes with a micromesh/nanomesh structure were fabricated on a polyimide substrate using UV lithography and wet etching to produce flexible transparent conducting electrodes (TCEs). Well-defined mesh electrodes were realized through the use of high-quality Cu thin films. The films were fabricated using radio-frequency (RF) sputtering with a single-crystal Cu target--a simple but innovative approach that overcame the low oxidation resistance of ordinary Cu. Hybrid Cu mesh electrodes were fabricated by adding a capping layer of either ZnO or Al-doped ZnO. The sheet resistance and the transmittance of the electrode with an Al-doped ZnO capping layer were 6.197 ohm/sq and 90.657%, respectively, and the figure of merit was 60.502 × 10(-3)/ohm, which remained relatively unchanged after thermal annealing at 200 °C and 1,000 cycles of bending. This fabrication technique enables the mass production of large-area flexible TCEs, and the stability and high performance of Cu mesh hybrid electrodes in harsh environments suggests they have strong potential for application in smart displays and solar cells.
ChemInform Abstract: REACTIVITY OF PYRROLE PIGMENTS. PART II. DEPROTONATION OF 3‐PYRROLIN‐2‐ONES (1981)

Abstract Aus Untersuchungen des ′HPH‐Austausches und vergleichenden photometrischen Bestimmungen der pKia‐Werte der Pyrroline (I)‐(III) ergibt sich,‐daß (I),ein einfaches Modell zum Studium des Verhaltens von Gallenpigmenten, unter der Einwirkung von K‐tert.‐butoxid in tert.‐Butanol am N‐Atom deprotoniert wird.
ChemInform Abstract: 1‐3 ISOMERIZATION IN A SERIES OF PHOSPHORYLATED INDOLES (1978)

Abstract Das 1‐Indolyl‐phosphorigsäurediamid (II) hydrolysiert durch eine äquivalente Menge Wasser unter gleichzeitiger Isomerisierung zum 3‐Indolylphosphonit (I) und durch Alkoholezu "den O,O‐Dialkyl‐3‐indolylphosphoniten (III).
Origin of translocation barriers for polyelectrolyte chains (2009)

For single-file translocations of a charged macromolecule through a narrow pore, the crucial step of arrival of an end at the pore suffers from free energy barriers, arising from changes in intrachain electrostatic interaction, distribution of ionic clouds and solvent molecules, and conformational entropy of the chain. All contributing factors to the barrier in the initial stage of translocation are evaluated by using the self-consistent field theory for the polyelectrolyte and the coupled Poisson-Boltzmann description for ions without radial symmetry. The barrier is found to be essentially entropic due to conformational changes. For moderate and high salt concentrations, the barriers for the polyelectrolyte chain are quantitatively equivalent to that of uncharged self-avoiding walks. Electrostatic effects are shown to increase the free energy barriers, but only slightly. The degree of ionization, electrostatic interaction strength, decreasing salt concentration, and the solvent quality all result in increases in the barrier.
Handling Complex Queries in a Distributed Data Base (1979)

As part of the continuing development of the LADDER system [1] [2], we have substantially expanded the capabilities of the data base access component that serves as the interface between the natural-language front end of LADDER and the data base management systems on which the data is actually stored. SODA, the new data base access component, goes beyond its predecessor IDA [3], in that it accepts a wider range of queries and accesses multiple DBMSs. This paper is concerned with the first of these areas, and discusses how the expressive power of the query language was increased, how these changes affected query processing in a distributed data base, as well as what are some limitations of and planned extensions to the current system.
Cross‐linked trimers of bovine ribonuclease A: activity on double‐stranded RNA and antitumor action (1997)

Trimers of bovine pancreatic RNase A were obtained by cross-linking native RNase A with dimethyl suberimidate. They degrade double-stranded RNA more efficiently than dimers and monomers of RNase A, and display significant cytotoxic and/or cytostatic actions against C4-I cells (a human cell line derived from squamous carcinoma of the uterus cervix). On the same cell line cross-linked dimers of RNase A appear to be ineffective.
Categorization in unsupervised neural networks: the Eidos model (1996)

Proulx and Begin (1995) recently explained the power of a learning rule that combines Hebbian and anti-Hebbian learning in unsupervised auto-associative neural networks. Combined with the brain-state-in-a-box transmission rule, this learning rule defines a new model of categorization: the Eidos model. To test this model, a simulated neural network, composed of 35 interconnected units, is subjected to an alphabetical characters recognition task. The results indicate the necessity of adding two parameters to the model: a restraining parameter and a forgetting parameter. The study shows the outstanding capacity of the model to categorize highly altered stimuli after a suitable learning process. Thus, the Eidos model seems to be an interesting option to achieve categorization in unsupervised neural networks.
Feasibility and acceptability of orientation and mobility instructors delivering the LiFE falls prevention program to older people with vision impairment. (2017)

Abstract Older people with vision impairment are at an increased risk of falls. Though exercise-based intervention can reduce falls in the general population, this strategy has not been successful among people with vision impairment. We evaluated the feasibility and acceptability of the LiFE program, a home-based fall prevention program, for people aged over 50 with vision impairment (n=16). The program was successfully delivered by orientation and mobility instructors to clients of Guide Dogs NSW/ACT, a community service organisation. Interviews with study participants showed engagement and adherence and there were positive trends in physical outcome measures supporting this program as a promising approach to enhance strength and balance, ultimately reducing the likelihood of falls in older people with vision impairment.
Effect of Various Levels of Avilamycin on the Performance of Growing-Finishing Swine1 (1987)

A series of 12 trials involving 1,710 crossbred pigs was conducted at eight geographical locations in the United States to determine the effect of avilamycin on average daily gain (ADG), average daily feed (ADF) and feed-to-gain ratio (F/G) of growing-finishing swine. Eight of 12 trials evaluated avilamycin concentrations at 0, 5, 10, 20, 40 and 60 ppm, while an additional four trials evaluated avilamycin concentrations at 0, 10, 20 and 40 ppm in swine grower and finisher diets fed ad libitum. All trials were conducted using a randomized complete block design with data from the 12 trials pooled for statistical analysis. Pigs fed 5, 10, 20, 40 or 60 ppm avilamycin had increased (P less than .05) ADG over control pigs. No differences were detected for ADF between control and avilamycin-fed pigs. Pigs fed 10, 20, 40 or 60 ppm avilamycin had improved (P less than .05) F/G over control animals. Average daily gain, ADF and F/G for pigs fed 0, 5, 10, 20, 40 or 60 ppm avilamycin were: 749, 763, 767, 769, 771 and 771 g; 2.38, 2.40 2.39, 2.41, 2.38 and 2.38 kg; and 3.17, 3.15, 3.12, 3.13, 3.09 and 3.09, respectively. Linear plateau procedures showed that the effective dose range of avilamycin for the growing-finishing phase is 5 to 10 ppm for improving ADG and 10 to 60 ppm for improving F/G.
Functional properties of proteins in foods: A survey (1976)

Proteins for foods, in addition to providing nutrition, should also possess specific functional properties that facilitate processing and serve as the basis of product performance. Functional properties of proteins for foods connote the physicochemical properties which govern the behavior of protein in foods. This general article collates the published information concerning the major functional properties of food proteins, e.g., solubility, binding properties, surfactant properties, viscogenic texturizing characteristics, etc. The effects of extraction and processing on functional properties and possible correlations between structure and function are discussed, in relation to practical performance in food systems. Modification of proteins to improve functional characteristics is briefly mentioned.
Simulated annealing inversion of multimode Rayleigh wave dispersion curves for geological structure (2002)

A R Y Simulated annealing was used to invert fundamental and higher-mode Rayleigh wave dispersion curves simultaneously for an S-wave velocity profile. The inversion was applied to near-surface seismic data (with a maximum depth of investigation of around 10 m) obtained over a thick lacustrine clay sequence. The geology was described either in terms of discrete layers or by a superposition of Chebyshev polynomials in the inversion and the contrasting results compared. Simulated annealing allows for considerable flexibility in model definition and parametrization and seeks a global rather than a local minimum in a misfit function. It has the added advantage in that it can be used to determine uncertainties in inversion parameters, thereby highlighting features in an inverted profile that should be interpreted with caution. Results show that simulated annealing works well for the inversion of multimodal near-surface Rayleigh wave dispersion curves relative to the same inversion that employs only the fundamental mode.
Prototypical Networks for Few-shot Learning (2017)

We propose prototypical networks for the problem of few-shot classification, where a classifier must generalize to new classes not seen in the training set, given only a small number of examples of each new class. Prototypical networks learn a metric space in which classification can be performed by computing distances to prototype representations of each class. Compared to recent approaches for few-shot learning, they reflect a simpler inductive bias that is beneficial in this limited-data regime, and achieve excellent results. We provide an analysis showing that some simple design decisions can yield substantial improvements over recent approaches involving complicated architectural choices and meta-learning. We further extend prototypical networks to zero-shot learning and achieve state-of-the-art results on the CU-Birds dataset.
Content-Based Networking: A New Communication Infrastructure (2001)

1 Introduction Distributed auction systems, such as e-BayTM, and information sharing systems, such as NapsterTM and Gnutella, are classes of network applications that have had an impressive growth in popularity over the past few years. Other examples are applications especially suited to mobile and wireless computing platforms, such as instant messaging, personalized news distribution, and service discovery. E-bay implements a traditional auction system, where sellers advertise items for sale and where buyers can bid on selected items. Napster and Gnutella allow users
Leukotriene B4-induced neutrophil-mediated endothelial leakage in vitro and in vivo (1991)

The vascular leakage of macromolecules seen in several models after application of leukotriene B4 (LTB4) is mediated by neutrophil granulocytes. We describe here an in vitro assay for this event. Human umbilical vein endothelial cells were grown on polycarbonate filters separating luminal and abluminal compartments of fluid. Both clearance rate of fluorescein isothiocyanate albumin and neutrophil migration through the endothelial monolayer were increased when LTB4 (10-100 nM) was added to the abluminal compartment. However, if LTB4 was instead added to the luminal compartments together with the neutrophils, no migration or change in clearance could be detected. These findings were confirmed in vivo in the cheek pouches of anesthetized hamsters, where extravascular application of LTB4 induced intravascular adhesion of neutrophils, accompanied by neutrophil-dependent vascular leakage. On the other hand, intravascular deposition of LTB4 with micropipettes induced adhesion of leukocytes but no leakage. In conclusion, the presence of neutrophils adhering to endothelium does not necessarily imply the development of neutrophil-mediated vascular leakage. Instead, the leakage appears connected to the process of neutrophil chemotaxis.
PROTEIN FAMILIES AND THEIR EVOLUTION—A STRUCTURAL PERSPECTIVE (2005)

We can now assign about two thirds of the sequences from completed genomes to as few as 1400 domain families for which structures are known and thus more ancient evolutionary relationships established. About 200 of these domain families are common to all kingdoms of life and account for nearly 50% of domain structure annotations in the genomes. Some of these domain families have been very extensively duplicated within a genome and combined with different domain partners giving rise to different multidomain proteins. The ways in which these domain combinations evolve tend to be specific to the organism so that less than 15% of the protein families found within a genome appear to be common to all kingdoms of life. Recent analyses of completed genomes, exploiting the structural data, have revealed the extent to which duplication of these domains and modifications of their functions can expand the functional repertoire of the organism, contributing to increasing complexity.
Interleukin-1β and Tumor Necrosis Factor-α Produce Distinct, Time-dependent Patterns of Acute Arthritis in the Rat Knee (2004)

Interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha) synergistically induce and sustain arthritis. Two competing hypotheses of arthritis induction are 1) that TNF preferentially mediates inflammation, whereas IL-1 impels bone destruction, or 2) that either cytokine controls the entire process. In this study, these propositions were tested in two experiments by instilling IL-1beta or TNF-alpha into one knee of Lewis rats (n = 6/group) to incite arthritis, after which semiquantitative scores for inflammation, bone resorption, osteoclasts, and cartilage integrity were acquired. In the induction study, IL-1beta or TNF-alpha (3, 10, or 30 micro g) was given once to incite arthritis. After 2 days, IL-1beta induced significant, dose-dependent increases in inflammation (mild to marked), bone resorption (minimal to moderate), and osteoclasts (minimal to moderate). In contrast, TNF-alpha induced minimal to mild inflammation but had little impact on resorption or osteoclasts. Both IL-1 and TNF (>/=10 micro g) yielded mild cartilage degeneration. Most lesion scores in TNF-treated rats were significantly lower than those in animals given the same dose of IL-1beta. In the persistence study, rats were injected once with IL-1 or TNF (10 micro g) and maintained for 2, 3, or 7 days. IL-1beta significantly enhanced inflammation (all 3 days), bone resorption (days 2 and 3), osteoclasts (days 2 and 3), and cartilage matrix loss (days 2 and 3), whereas TNF-alpha augmented inflammation (days 2 and 3) and cartilage degeneration (day 2) but not bone resorption or osteoclasts. Thus, both IL-1beta and TNF-alpha can launch inflammation, but IL-1beta drives skeletal destruction.
Thymine DNA Glycosylase Can Rapidly Excise 5-Formylcytosine and 5-Carboxylcytosine (2011)

Thymine DNA glycosylase (TDG) excises T from G·T mispairs and is thought to initiate base excision repair (BER) of deaminated 5-methylcytosine (mC). Recent studies show that TDG, including its glycosylase activity, is essential for active DNA demethylation and embryonic development. These and other findings suggest that active demethylation could involve mC deamination by a deaminase, giving a G·T mispair followed by TDG-initiated BER. An alternative proposal is that demethylation could involve iterative oxidation of mC to 5-hydroxymethylcytosine (hmC) and then to 5-formylcytosine (fC) and 5-carboxylcytosine (caC), mediated by a Tet (ten eleven translocation) enzyme, with conversion of caC to C by a putative decarboxylase. Our previous studies suggest that TDG could excise fC and caC from DNA, which could provide another potential demethylation mechanism. We show here that TDG rapidly removes fC, with higher activity than for G·T mispairs, and has substantial caC excision activity, yet it cannot remove hmC. TDG excision of fC and caC, oxidation products of mC, is consistent with its strong specificity for excising bases from a CpG context. Our findings reveal a remarkable new aspect of specificity for TDG, inform its catalytic mechanism, and suggest that TDG could protect against fC-induced mutagenesis. The results also suggest a new potential mechanism for active DNA demethylation, involving TDG excision of Tet-produced fC (or caC) and subsequent BER. Such a mechanism obviates the need for a decarboxylase and is consistent with findings that TDG glycosylase activity is essential for active demethylation and embryonic development, as are mechanisms involving TDG excision of deaminated mC or hmC.
Management of herpes zoster (shingles) and postherpetic neuralgia. (2000)

Herpes zoster (commonly referred to as "shingles") and postherpetic neuralgia result from reactivation of the varicella-zoster virus acquired during the primary varicella infection, or chickenpox. Whereas varicella is generally a disease of childhood, herpes zoster and post-herpetic neuralgia become more common with increasing age. Factors that decrease immune function, such as human immunodeficiency virus infection, chemotherapy, malignancies and chronic corticosteroid use, may also increase the risk of developing herpes zoster. Reactivation of latent varicella-zoster virus from dorsal root ganglia is responsible for the classic dermatomal rash and pain that occur with herpes zoster. Burning pain typically precedes the rash by several days and can persist for several months after the rash resolves. With postherpetic neuralgia, a complication of herpes zoster, pain may persist well after resolution of the rash and can be highly debilitating. Herpes zoster is usually treated with orally administered acyclovir. Other antiviral medications include famciclovir and valacyclovir. The antiviral medications are most effective when started within 72 hours after the onset of the rash. The addition of an orally administered corticosteroid can provide modest benefits in reducing the pain of herpes zoster and the incidence of postherpetic neuralgia. Ocular involvement in herpes zoster can lead to rare but serious complications and generally merits referral to an ophthalmologist. Patients with postherpetic neuralgia may require narcotics for adequate pain control. Tricyclic antidepressants or anticonvulsants, often given in low dosages, may help to control neuropathic pain. Capsaicin, lidocaine patches and nerve blocks can also be used in selected patients.
Continuous Compartment Pressure Monitoring for Tibia Fractures: Does It Influence Outcome? (2006)

Continuous compartment pressure monitoring is not indicated in alert patients who are adequately observed.
Development of apoptosis‐resistant dihydrofolate reductase‐deficient Chinese hamster ovary cell line (2003)

Apoptosis-resistant dihydrofolate reductase-deficient CHO cell line (dhfr(-) CHO-bcl2) was developed by introduction of the bcl-2 gene into the dhfr(-) CHO cell line (DUKX-B11, ATCC CRL-9096) and subsequent selection of clones stably overexpressing Bcl-2 in the absence of selection pressure. When the dhfr(-) CHO-bcl2 cell line was used as a host cell line for development of a recombinant CHO (rCHO) cell line expressing a humanized antibody, it displayed stable expression of the bcl-2 gene during rCHO cell line development and no detrimental effect of Bcl-2 overexpression on specific antibody productivity. Taken together, the results obtained demonstrate that the use of an apoptosis-resistant dhfr(-) CHO cell line as the host cell line saves the effort of establishing an apoptosis-resistant rCHO cell line and expedites the development process of apoptosis-resistant rCHO cells producing therapeutic proteins.
Nucleolysis of the Rabbit Intervertebral Disc Using Chondroitinase ABC (1991)

Spine is an international, peer-reviewed, bi-weekly periodical that considers for publication original articles in the field of spine. It is the leading subspecialty journal for the treatment of spinal disorders. Only original papers are considered for publication with the understanding that they are contributed solely to Spine. The Journal does not publish articles reporting material that has been reported at length elsewhere.
Conduction-based modeling of the biofilm anode of a microbial fuel cell (2007)

The biofilm of a microbial fuel cell (MFC) experiences biofilm-related (growth and mass transport) and electrochemical (electron conduction and charger-transfer) processes. We developed a dynamic, one-dimensional, multi-species model for the biofilm in three steps. First, we formulated the biofilm on the anode as a "biofilm anode" with the following two properties: (1) The biofilm has a conductive solid matrix characterized by the biofilm conductivity (kappa(bio)). (2) The biofilm matrix accepts electrons from biofilm bacteria and conducts the electrons to the anode. Second, we derived the Nernst-Monod expression to describe the rate of electron-donor (ED) oxidation. Third, we linked these components using the principles of mass balance and Ohm's law. We then solved the model to study dual limitation in biofilm by the ED concentration and local potential. Our model illustrates that kappa(bio) strongly influences the ED and current fluxes, the type of limitation in biofilm, and the biomass distribution. A larger kappa(bio) increases the ED and current fluxes, and, consequently, the ED mass-transfer resistance becomes significant. A significant gradient in ED concentration, local potential, or both can develop in the biofilm anode, and the biomass actively respires only where ED concentration and local potential are high. When kappa(bio) is relatively large (i.e., > or =10(-3) mS cm(-1)), active biomass can persist up to tens of micrometers away from the anode. Increases in biofilm thickness and accumulation of inert biomass accentuate dual limitation and reduce the current density. These limitations can be alleviated with increases in the specific detachment rate and biofilm density.
What's in the eyes for attentive input (2003)

Eye-tracking systems hold some of the greatest potential among AUIs. Here, two systems that focus on eye gazing demonstrate how this simple form of visual attention can perform a level of common interactive tasks.
A study in clinical cancer immunotherapy (1970)

Twenty patients with advanced cancer have been treated by a vigorous course of immunotherapy, with the dual aim of clinical improvement and obtaining evidence of enhancement of immune response to the tumor. Although the clinical response has not been striking, it has proved to be a safe procedure, and evidence has been obtained that cellular immune response can be enhanced by this procedure. Usefulness of dermal hypersensitivity reactions in monitoring cancer immunity has been confirmed and correlation has been found between this enhanced immune response and apparent clinical improvement. It is believed that the results of this investigation add further justification for carefully controlled trials of immunization earlier in the disease. However, some results suggest that antigenic modulation of cancer cells has occurred in the face of immune attack. If substantiated, this may be a further factor militating against successful immunotherapy of cancer.
Preparation of some new intercalating europium(III) sensitizers (1996)

The synthesis of phenanthridinium salts linked to a chelating phenanthroline-2,9-dicarboxylic acid group, as in 1 and 2, is described. These derivatives behave as useful probes for the identification of DNA single strands in a new homogeneous assay.