gebhart/patrepeval huggingface dataset:
Vision and IMU Data Fusion: Closed-Form Solutions for Attitude, Speed, Absolute Scale, and Bias Determination (2011)

This paper investigates the problem of vision and inertial data fusion. A sensor assembling that is constituted by one monocular camera, three orthogonal accelerometers, and three orthogonal gyroscopes is considered. The first paper contribution is the analytical derivation of all the observable modes, i.e., all the physical quantities that can be determined by only using the information in the sensor data that are acquired during a short time interval. Specifically, the observable modes are the speed and attitude (roll and pitch angles), the absolute scale, and the biases that affect the inertial measurements. This holds even in the case when the camera only observes a single point feature. The analytical derivation of the aforementioned observable modes is based on a nonstandard observability analysis, which fully accounts for the system nonlinearities. The second contribution is the analytical derivation of closed-form solutions, which analytically express all the aforementioned observable modes in terms of the visual and inertial measurements that are collected during a very short time interval. This allows the introduction of a very simple and powerful new method that is able to simultaneously estimate all the observable modes with no need for any initialization or a priori knowledge. Both the observability analysis and the derivation of the closed-form solutions are carried out in several different contexts, including the case of biased and unbiased inertial measurements, the case of a single and multiple features, and in the presence and absence of gravity. In addition, in all these contexts, the minimum number of camera images that are necessary for the observability is derived. The performance of the proposed approach is evaluated via extensive Monte Carlo simulations and real experiments.
Serum and Dietary Magnesium and Incidence of Atrial Fibrillation in Whites and in African Americans (2013)

Lower serum Mg was associated with a higher AF risk, and this association was not different between whites and African Americans. Dietary Mg was not associated with AF risk.
Screening for Suicidal Ideation and Attempts among Emergency Department Medical Patients: Instrument and Results from the Psychiatric Emergency Research Collaboration (2013)

Joint Commission National Patient Safety Goal 15 calls for organizations "to identify patients at risk for suicide." Overt suicidal behavior accounts for 0.6% of emergency department (ED) visits, but incidental suicidal ideation is found in 3%-11.6%. This is the first multicenter study of suicide screening in EDs. Of 2,243 patients in six diverse emergency settings, 1,068 (47.7%) were screened with a brief instrument. Depression was endorsed by 369 (34.5%); passive suicidal ideation by 79 (7.3%); and active suicidal ideation by 24 (2.3%). One hundred thirty-seven (12.8%) reported prior attempts, including 35 (3.3%) with current suicidal ideation. Almost half of those with current ideation had a prior attempt (43.8%) versus those without current ideation, 10.3%, χ2 (1) = 75.59, p < .001. Twenty cases (25%) were admitted to medical services, but only 10 (12.5%) received mental health assessment; none were admitted directly to a psychiatry service. The prevalence of suicidal ideation here is similar to previous studies but the frequency of prior attempts has not been reported. The 35 cases with current ideation and prior attempt are at risk. As they did not present psychiatrically, they would likely have gone undetected. Despite reporting these cases to clinical staff, few received risk assessment.
Find your Way by Observing the Sun and Other Semantic Cues (2016)

In this paper we present a robust, efficient and affordable approach to self-localization which does not require neither GPS nor knowledge about the appearance of the world. Towards this goal, we utilize freely available cartographic maps and derive a probabilistic model that exploits semantic cues in the form of sun direction, presence of an intersection, road type, speed limit as well as the ego-car trajectory in order to produce very reliable localization results. Our experimental evaluation shows that our approach can localize much faster (in terms of driving time) with less computation and more robustly than competing approaches, which ignore semantic information.
Multi-Rate Convolutional Codes (1998)

The requirement for increased flexibility in order to support the many different services in wireless communication has motivated the search for new, improved convolutional codes with a large number of different code rates. A new design criterion is introduced which results in codes with better performance on both AWGN channels and Rayleigh fading channels. These codes, called Optimum Distance Spectrum (ODS) convolutional codes, are tabulated for code rate 1/2, 1/3 and 1/4, for different constraint lengths. The ODS codes are used as a basis for deriving a large number of codes with different rates. Optimum puncturing patterns and spectra are shown for puncturing periods between 2 and 8, parent code rates 1/2, 1/3, and 1/4 and constraint lengths between 3 and 15. A large set of rate-compatible punctured codes are also presented, as well as a detailed evaluation on RCPC puncturing pattern search. Finally the ODS codes are used as starting codes for searching additional generator polynomi...
The Paragon Algorithm, a Next Generation Search Engine That Uses Sequence Temperature Values and Feature Probabilities to Identify Peptides from Tandem Mass Spectra (2007)

The Paragon Algorithm, a novel database search engine for the identification of peptides from tandem mass spectrometry data, is presented. Sequence Temperature Values are computed using a sequence tag algorithm, allowing the degree of implication by an MS/MS spectrum of each region of a database to be determined on a continuum. Counter to conventional approaches, features such as modifications, substitutions, and cleavage events are modeled with probabilities rather than by discrete user-controlled settings to consider or not consider a feature. The use of feature probabilities in conjunction with Sequence Temperature Values allows for a very large increase in the effective search space with only a very small increase in the actual number of hypotheses that must be scored. The algorithm has a new kind of user interface that removes the user expertise requirement, presenting control settings in the language of the laboratory that are translated to optimal algorithmic settings. To validate this new algorithm, a comparison with Mascot is presented for a series of analogous searches to explore the relative impact of increasing search space probed with Mascot by relaxing the tryptic digestion conformance requirements from trypsin to semitrypsin to no enzyme and with the Paragon Algorithm using its Rapid mode and Thorough mode with and without tryptic specificity. Although they performed similarly for small search space, dramatic differences were observed in large search space. With the Paragon Algorithm, hundreds of biological and artifact modifications, all possible substitutions, and all levels of conformance to the expected digestion pattern can be searched in a single search step, yet the typical cost in search time is only 2-5 times that of conventional small search space. Despite this large increase in effective search space, there is no drastic loss of discrimination that typically accompanies the exploration of large search space.
GLUT1 expression in human breast carcinoma: correlation with known prognostic markers. (1996)

1) Glut1 expression is increased in breast cancers with higher grade and proliferative activity, and 2) glucose transport in the majority of breast cancers may be mediated by a glucose transporters other than Glut1.
Strategies in the Preparation of DNA Oligonucleotide Arrays for Diagnostic Applications (2001)

This report emphasizes the interfacial chemistry that is required to ensure proper attachment of oligonucleotides onto the surface of microarrays. For example, strategies for the covalent attachment of pre-synthesized oligonucleotides to glass slides, gold films, polyacrylamide gel pads, polypyrrole films, and optical fibers are surveyed in an attempt to better define the parameters for optimal formation and detection of DNA hybrids. These parameters include among others, the nature and length of the linkers attaching oligonucleotides to the arrays, and the surface density of oligonucleotides required for unhindered hybridization with DNA targets. Sensitive detection methods such as the use of light-scattering techniques, molecular beacons, surface plasmon resonance, attenuated total internal reflection-FTIR, and the evanescent field excitation of fluorescence from surface-bound fluorophores have been developed to study the kinetics and specificity of hybridization events. Finally, the synthesis of oligonucleotides directly on glass surfaces and polypropylene sheets has been investigated to enable DNA sequencing by hybridization and achieve oligonucleotide densities of ca. 10(6) sequences per cm(2) on DNA chips.
[Risk factors prevalence of subclinical forms of cardiovascular diseases among subjects of working age]. (2009)

The prevalence of preclinical forms of cardiovascular diseases diagnosed by EchoCG, Holter monitoring, functional test, ultrasound of extracranial arteries was analysed among practically healthy subjects at risk of CHD who underwent primary outpatient examination in 1986-1995 Another 172 persons at high risk of cardiovascular disorders were included in the "vascular run" program for short-term medical examination. It is shown that the frequency of pathological conditions diagnosed by the above methods increases in case of combined arterial hypertension and metabolic disturbances (dyslipidemia, excessive body mass, glucose intolerance). Prospective observations revealed high prognostic value of comprehensive assessment of the cardiovascular system. It is concluded that a program of primary evaluation of the cardiovascular system using functional diagnostic tests for the discovery of preclinical disorders in practically healthy subjects should be developed on an individual basis with regard for risk factors and their magnitude.
Study on the characteristics of an imaging spectrum system by means of an acousto-optic tunable filter (1993)

The spectrally agile staring sensor (SASS) is an instrument system that is able to acquire image and spectrum information simultaneously. We analyze the expression of SNR and overall perlormance of the SASS system consisting of an acousto-optic tunable filter and point out improvement methods and limiting factors of the system performance. The complete SASS system setup is constructed. By means of this setup, the theoretical analysis is verified and the image and spectrum information of the simulated target is obtained. These results demonstrate the ability of the SASS to acquire image and spectrum information.
Effect of poly(lactic‐co‐glycolic acid) contact on maturation of murine bone marrow‐derived dendritic cells (2006)

Understanding of biomaterial adjuvant effect and its mechanisms is essential for the effective design and selection of appropriate materials for specific applications. We have previously shown that poly(lactic-co-glycolic acid) (PLGA), one of the most commonly studied polymers in tissue engineering, supports an adjuvant effect as measured by enhanced immune response against a co-delivered model antigen, which was dependent on the form of the biomaterial. Furthermore, we have shown that PLGA induces the maturation of human peripheral blood mononuclear cell-derived dendritic cells (DCs) in vitro. In this study, the effect of PLGA contact on the maturation of murine bone marrow-derived DCs was investigated in part to explain the biomaterial adjuvant effect observed. Treatment of bone marrow-derived DCs from C57BL6 mice with PLGA microparticles or films lead to maturation of these cells as exemplified by increased expression of co-stimulatory molecules CD80 and CD86 and production of proinflammatory cytokines TNF-alpha and IL-6. These results suggest that PLGA contact induces maturation of murine DCs, supporting our observations with human DCs. With the techniques developed in this study and given the results, our future goal is to utilize transgenic murine models to delineate the mechanisms of biomaterial-induced DC maturation.
A coaxial-radial line junction with a top loading disk for broadband matchings (1999)

A new coaxial–radial transmission-line junction is proposed and characterized by a rigorous full-wave modal-expansion method. The proposed structure modifies the conventional coaxial–radial junction by introducing a circular disk on the top plate of the radial transmission line whose parameters can be adjusted for broadband matchings. Two examples are presented to demonstrate the junction's practicality. ©1999 John Wiley &amp; Sons, Inc. Microwave Opt Technol Lett 22: 87–90, 1999.
Purification and characterization of the mu opiate receptor from rat brain using affinity chromatography. (1985)

Opiate receptors have been solubilized from rat neural membranes and purified 500-fold (relative to the crude solubilized extract) by affinity chromatography. Active receptors were solubilized by using 3-[( 3-cholamidopropyl)-dimethylammonio]-1-propanesulfonate (CHAPS), a zwitterionic derivative of cholic acid. Affinity chromatography was carried out using Affi-Gel 401, a sulfhydryl derivative of agarose to which "hybromet," a newly synthesized opioid ligand with high affinity for the mu receptor, had been attached. Scatchard analysis of [3H]etorphine binding to the purified receptor revealed a single class of high-affinity sites (Kd = 1.4 nM; Bmax = 2800 fmol/mg of protein). Half-maximal binding was achieved at approximately equal to 1 nM. Activity was markedly inhibited by protein modifying reagents, findings which suggest that the sites are proteinaceous. Opiate binding activity was also inhibited by the guanyl nucleotide GTP. Electrophoresis of the purified material under denaturing conditions revealed three subunits of molecular weights 94,000, 44,000, and 35,000. The inhibitory guanyl nucleotide binding protein (Ni) implicated in opiate action has been shown to be comprised of two subunits of molecular weights 42,000 and 35,000. Thus, the opiate receptor may be an aggregate of multiple protein components that may include a guanyl nucleotide binding protein.
Monoclonal antibodies to human renal cell carcinoma: recognition of shared and restricted tissue antigens. (1985)

Monoclonal antibodies (MABs) reactive with human renal cell carcinoma (RCC) were generated following immunization of mice with either RCC homogenates, RCC cell lines, or fetal kidney homogenates. The characteristics of four highly reactive immunoglobulin G1 MABs, designated UMVA-RCC-A6H, UMVA-RCC-A36, UMVA-RCC-C5H and UMVA-RCC-D5D are presented. The screening process consisted of a cell binding enzyme-linked immunosorbent assay and immunohistological examination of tumor, normal, and fetal tissue sections. The MABs illustrated various degrees of antigen restriction: A6H identified an antigen common to RCC, some lung and colon carcinomas, the proximal renal tubules but no other normal tissues; A36 reacted with most human tumors, the renal tubules, and many other normal tissues; C5H reacted with nearly every human cancer but of the normal tissues, only the renal glomerulus shared this antigen; D5D was very restrictive, reacting with many although not all RCC and no other cancers or normal tissues with the exception of an occasional reactivity with a Bowman's capsule. Metastatic RCC and RCC xenografts expressed these antigens. None of the MABs participated in complement-mediated cytotoxicity. In immunoprecipitation studies with L-[methyl-3H]methionine and [3H]glucosamine-HCl metabolically labeled RCC cells, C5H was shown to be associated with an antigen of Mr 115,000.
The North American Menopause Society at 25 years (2014)

Utian, Wulf H. MD, PhD, DSc(Med); Schiff, Isaac MD; Kronenberg, Fredi PhD; Shifren, Jan L. MD, NCMP; Gass, Margery L.S. MD, NCMP Author Information
Improved induction of melanoma-reactive CTL with peptides from the melanoma antigen gp100 modified at HLA-A*0201-binding residues (1996)

Recognition of the melanoma Ag gp100 by tumor-infiltrating lymphocytes (TIL) in vitro has been correlated with tumor regression in patients with metastatic melanoma treated with the adoptive transfer of TIL plus IL-2. Three common gp100 epitopes have been identified that are recognized in the context of HLA-A2 by TIL from different patients: G9154 (KTWGQYWQV), G9209 (ITDQVPFSV), and G9280 (YLEPGPVTA). Upon stimulation with these peptides, melanoma-reactive CTL could be induced in vitro from PBL of some HLA-A2+ melanoma patients. However, numerous restimulations were required, and specific reactivity could not be generated in many patients. Therefore, to enhance the immunogenicity of gp100 peptides, amino acid substitutions were introduced into G9154, G9209, and G9280 at HLA-A*0201-binding anchor positions, but not at TCR contact residues, to increase peptide class I MHC-binding affinity. Several modified gp100 peptides bound with greater affinity to HLA-A*0201 than unmodified peptides and were recognized by TIL specific for the natural epitopes. These peptides were used to sensitize PBL from HLA-A2+ melanoma patients in vitro using peptide-pulsed autologous PBMC as stimulators. After five weekly restimulations with either the native G9209 or G9280 peptide, melanoma-reactive CTL could only be induced from two of seven patients. However, amino acid substitutions in these peptides enabled the induction of melanoma-reactive CTL from all seven patients. These results suggest that modified gp100 peptides may be more immunogenic than the native epitopes, and may be useful in immunotherapy protocols for patients with melanoma.
Continuous‐Flow CH Borylation of Arene Derivatives (2010)

Abstract A new continuous‐flow system for CH borylation has been developed. An insoluble catalyst prepared from chloro(1,5‐cyclooctadien)iridium(I) dimer and 2,2′‐bipyridine‐4,4′‐dicarboxylic acid in the presence of bis(pinacolato)diboron exhibited high reactivity under continuous‐flow processing without the loss of expensive iridium metal.
Discourse Structure and Anaphora (1987)

Barbara Fox's thoughtful study examines the use of anaphora in both written and spoken discourse. Any treatment of anaphora must consider the hierarchical of its source texts-type. Texts may be produced and heard or read linearly, but they are designed and understood hierarchically. Discourse Structure and Anaphora goes beyond the information processing concerns of cognitive science to assess the critical role played in all text-types by social, interactional and affective factors. It also considers the fact that texts are organised by socially accepted conventions. Using conversation analysis and rhetorical structure analysis, this book looks at the distribution of pronouns and full noun phrases in three different genres of English, taking data from naturally occurring face-to-face and telephone conversations, small newspaper and magazine articles and a psychoanalytic biography.
A comparative sequence analysis to revise the current taxonomy of the family Coronaviridae (2003)

The Coronaviridae family, comprising the Coronavirus and Torovirus genera, is part of the Nidovirales order that also includes two other families, Arteriviridae and Roniviridae. Based on genetic and serological relationships, groups 1, 2 and 3 were previously recognized in the Coronavirus genus. In this report we present results of comparative sequence analysis of the spike (S), envelope (E), membrane (M), and nucleoprotein (N) structural proteins, and the two most conserved replicase domains, putative RNA-dependent RNA polymerase (RdRp) and RNA helicase (HEL), aimed at a revision of the Coronaviridae taxonomy. The results of pairwise comparisons involving structural and replicase proteins of the Coronavirus genus were consistent and produced percentages of sequence identities that were distributed in discontinuous clusters. Inter-group pairwise scores formed a single cluster in the lowest percentile. No homologs of the N and E proteins have been found outside coronaviruses, and the only (very) distant homologs of S and M proteins were identified in toroviruses. Intragroup sequence conservation was higher, although for some pairs, especially those from the most diverse group 1, scores were close or even overlapped with those from the intergroup comparisons. Phylogenetic analysis of six proteins using a neighbor-joining algorithm confirmed three coronavirus groups. Comparative sequence analysis of RdRp and HEL domains were extended to include arterivirus and ronivirus homologs. The pairwise scores between sequences of the genera Coronavirus and Torovirus (22-25% and 21-25%) were found to be very close to or overlapped with the value ranges (12 to 22% and 17 to 25%) obtained for interfamily pairwise comparisons, but were much smaller than values derived from pairwise comparisons within the Coronavirus genus (63-71% and 59-67%). Phylogenetic analysis confirmed toroviruses and coronaviruses to be separated by a large distance that is comparable to those between established nidovirus families. Based on comparison of these scores with those derived from analysis of separate ranks of several multi-genera virus families, like the Picornaviridae, a revision of the Coronaviridae taxonomy is proposed. We suggest the Coronavirus and Torovirus genera to be re-defined as two subfamilies within the Coronavirdae or two families within Nidovirales, and the current three informal coronavirus groups to be converted into three genera within the Coronaviridae.
Prognostic Value of Tubular Proteinuria and Enzymuria in Nonoliguric Acute Tubular Necrosis (2004)

In nonoliguric ATN, increased urinary excretion of cystatin C and alpha(1)-microglobulin may predict an unfavorable outcome, as reflected by the requirement for RRT.
Olefin Metathesis in the Ionic Liquid 1‐Butyl‐3‐methylimidazolium Hexafluorophosphate Using a Recyclable Ru Catalyst: Remarkable Effect of a Designer Ionic Tag (2003)

Designer labels: Ruthenium carbene complex 1 bearing an ionic tag was shown to be a highly reactive catalyst for the ring-closing metathesis of various diene and enyne substrates in minimally ionic solvent systems (see scheme; Bmim=1-butyl-3-methylimidazolium, Ts=toluene-4-sulfonyl). The catalyst can be repeatedly recycled and reused (up to at least 10 cycles) without significant loss of its activity, whereas other catalysts tested exhibited a dramatic diminishment in their activity upon recovery from the ionic layer.