gebhart/patrepeval huggingface dataset:
Estimation of central aortic forces in the ballistocardiogram under rest and exercise conditions (2009)

The ballistocardiogram (BCG) signal represents the movements of the body in response to cardiac ejection of blood. The BCG signal can change considerably under various physiological states; however, little information exists in literature describing how these forces are generated. A physical analysis is presented using a finite element model of thoracic aortic vasculature to quantify forces generated by the blood flow during the cardiac cycle. The traction at the fluid-solid interface of this deformable wall model generates a Central Aortic Force (CAF) which appears of similar magnitude to recorded BCG forces. The increased pulse pressure in an exercise simulation caused a significant increase in CAF, which is consistent with recent BCG measurements in exercise recovery.
Interdependency of local capillary density, blood flow, and metabolism in rat brains (1986)

Previous investigations have established a strong correlation between local cerebral blood flow (LCBF) and local cerebral glucose utilization (LCGU). In the present study the relationship between density of perfused brain capillaries and LCBF or LCGU was investigated in conscious and anesthetized rats. Perfused capillaries were stained by labeling the plasma with the gamma globulin-coupled fluorochromes, fluorescein isothiocyanate (FITC) and lissamine-rhodamine B 200 (RB 200). The density of perfused capillaries was determined in 12 different brain structures by fluorescence microscopy of embedded brain sections following coronal sectioning in a cryostat. Significant differences were found among brain structures investigated; the lowest density of perfused capillaries was found in the white matter (e.g., corpus callosum 162 fragments/mm2), whereas the highest values were determined in the structures of the auditory system (e.g., inferior colliculus 810 fragments/mm2). LCBF and LCGU were measured in two separate groups of rats using standard autoradiographic methods. In all three experimental groups, the same structures were identified and measured with a high degree of accuracy and local resolution. Density of perfused capillaries correlated well with LCBF (r = 0.93) and even better with LCGU (r = 0.97). In addition to the relationship between LCGU and LCBF established by earlier studies, these data show the intimate interrelationship between LCGU, density of perfused capillaries, and LCBF.
Estimation of Ultrasonic Attenuation and Mean Backscatterer Size via Digital Signal Processing (1984)

The backscattered rf signals from the lungs of fetal sheep during their last trimester of development were digitized and processed in an attempt to correlate ultrasonic parameters with measured functional parameters related to lung maturation. The broadband, post- TGC , rf signal of a commercial B-mode ultrasonic scanner was digitized at a sampling rate of 25 MHz. Sorting excluded data from regions of rib shadowing and other nonlung structures from analysis. The sorted data were used to estimate the slope of the ultrasonic attenuation coefficient with respect to frequency via linear regression on the average difference of the logarithm of power spectra from separated data segments. The power spectra were also corrected for attenuation, averaged and used to compute the power cepstrum of the backscattered signal which can be related to mean backscatterer radius. Results are presented for eight fetal sheep.
Interactive Detection Of 3D Models Of Building''S Roofings For The Estimation Of The Solar Energy Potential (2006)

Publication in the conference proceedings of EUSIPCO, Florence, Italy, 2006
Feature Extraction—A Pattern for Information Retrieval (1998)

to map from a large, complex problem space into a small, simple feature space. The mapping represents the creative part of the solution. Every type of application uses a different kind mapping. Mapping into the feature space is also the hard part of this pattern. Traditional searching algorithms are not viable for problems typical to the information retrieval domain. Since they were designed for exact matching, their use for similarity search is cumbersome. In contrast, feature extraction provides an elegant and efficient alternative. With information retrieval expanding into other fields, this pattern is applicable in a wide range of applications. 1 Context Digital libraries handle large amounts of information. They offer access to collections of documents represented in electronic format. According to Bruce Schatz [Sch97]: A digital library enables users to interact effectively with information distributed across a network. These network informa
A Low Frequency Electromagnetic Sensor for Indirect Measurement of Glucose Concentration: In Vitro Experiments in Different Conductive Solutions (2010)

In recent years there has been considerable interest in the study of glucose-induced dielectric property variations of human tissues as a possible approach for non-invasive glycaemia monitoring. We have developed an electromagnetic sensor, and we tested in vitro its ability to estimate variations in glucose concentration of different solutions with similarities to blood (sodium chloride and Ringer-lactate solutions), differing though in the lack of any cellular components. The sensor was able to detect the effect of glucose variations over a wide range of concentrations (∼78-5,000 mg/dL), with a sensitivity of ∼0.22 mV/(mg/dL). Our proposed system may thus be useful in a new approach for non-invasive and non-contact glucose monitoring.
GPU-Based Volume Ray-Casting with Advanced Illumination (2009)

Volume Abstract raycasting techniques are important for both visual arts and visualization. They allow an efficient generation of visual effects and the visualization of scientific data obtained by tomography or numerical simulation. Thanks to their flexibility, experts agree that GPU-based raycasting is the state-of-the art technique for interactive volume rendering. It will most likely replace existing slice-based techniques in the near future. Volume rendering techniques are also effective for the direct rendering of implicit surfaces used for soft body animation and constructive solid geometry. The lecture starts off with an in-depth introduction to the concepts behind GPU-based ray-casting to provide a common base for the following parts. The focus of this tutorial is on advanced illumination techniques which approximate the physically-based light transport more convincingly. Such techniques include interactive implementation of soft and hard shadows, ambient occlusion and simple Monte-Carlo based approaches to global illumination including translucency and scattering. With the proposed techniques, users are able to interactively create convincing images from volumetric data whose visual quality goes far beyond traditional approaches. The optical properties in participating media are defined using the phase function. Many approximations to the physically based light transport applied for rendering natural phenomena such as clouds or smoke assume a rather homogenous phase function model. For rendering volumetric scans on the other hand different phase function models are required to account for both surface-like structures and fuzzy boundaries in the data. Using volume rendering techniques, artists who create medical visualization for science magazines may now work on tomographic scans directly, without the necessity to fall back to creating polygonal models of anatomical structures.
Mast Cells Promote Blood Brain Barrier Breakdown and Neutrophil Infiltration in a Mouse Model of Focal Cerebral Ischemia (2015)

Blood brain barrier (BBB) breakdown and neuroinflammation are key events in ischemic stroke morbidity and mortality. The present study investigated the effects of mast cell deficiency and stabilization on BBB breakdown and neutrophil infiltration in mice after transient middle cerebral artery occlusion (tMCAo). Adult male C57BL6/J wild type (WT) and mast cell-deficient (C57BL6/J Kit(Wsh/Wsh) (Wsh)) mice underwent tMCAo and BBB breakdown, brain edema and neutrophil infiltration were examined after 4 hours of reperfusion. Blood brain barrier breakdown, brain edema, and neutrophil infiltration were significantly reduced in Wsh versus WT mice (P<0.05). These results were reproduced pharmacologically using mast cell stabilizer, cromoglycate. Wild-type mice administered cromoglycate intraventricularly exhibited reduced BBB breakdown, brain edema, and neutrophil infiltration versus vehicle (P<0.05). There was no effect of cromoglycate versus vehicle in Wsh mice, validating specificity of cromoglycate on brain mast cells. Proteomic analysis in Wsh versus WT indicated that effects may be via expression of endoglin, endothelin-1, and matrix metalloproteinase-9. Using an in vivo model of mast cell deficiency, this is the first study showing that mast cells promote BBB breakdown in focal ischemia in mice, and opens up future opportunities for using mice to identify specific mechanisms of mast cell-related BBB injury.
Christian Anti-Psychology and the Scientific Method (1987)

Christians are becoming increasingly vocal in their criticism of scientific psychology. In their criticisms Christian anti-psychologists have devalued knowledge gained through research and suggested both that the scientific method is inappropriate for studying human behavior and that the deception inherent in psychological research is immoral. This article examines these concerns and argues that the more subjective alternatives suggested by the critics of psychology suffer from many of the same limitations as scientific psychology and that taking such an approach would amount to substituting uncontrolled error for controlled error and uncontrolled deception for controlled deception.
Modulation techniques for multiple access to a hard-limiting satellite repeater (1966)

This paper considers the problem of devising modulation techniques that allow a large number of earth stations to use, simultaneously, a satellite repeater with the transfer characteristics of a wide-band hard-limiting amplifier. Four distinct classes of modulation techniques and their singular properties are described. Three important design considerations are discussed: repeater bandwidth and power sharing, network timing, and operational considerations. The paper provides a framework for further study of the multiple access problem. The hard-limiting repeater is shown to accommodate a wide variety of signal designs. No single class of multiple-access modulation techniques is found to be uniformly best in satisfying all needs of the diverse networks which can use communication satellites.
Optical rotatory dispersion of nitrobenzene derivatives. VII. Application of modified curtis rearrangement for determining the free carboxylic position in some partial esters of 3-nitro-phthalic and 4-nitrohemimellitic acid. (1975)

Conclusive evidence was obtained for the position of chiral alkyl groups in the esters of 3-nitrophthalic and 4-nitrohemimellitic acid, which are key substances demonstrating interesting chiroptical property due to twisting of the nitrobenzene chromophore controlled by the remote chiral groups through in phase twisting of the intervening substituents. Diphenylphosphorylazide (DPPA) was used as the reagent for modified Curtius rearrangement with good success. Since it acts specifically on carboxylic acid but not on ester function, only the former is converted to amine function. The amino compounds so derived were proved to be identical with the known substances. The method seems useful generally for determining the free carboxylic position in some partial esters of polycarboxylic acids.
Subcarrier multiple access for passive optical networks and comparison to other multiple access techniques (2002)

Subcarrier multiple access (SCMA) is described. It is a flexible access technique for passive optical networks (PONs), both for fiber-to-the home and fiber-to-the curb architectures. The main advantages of SCMA are the independence of the channels, which yields flexibility with respect to modulation format and evolution scenario, and the absence of synchronization between the different subscribers. Some results of SCMA experiments are presented. The capability of broadband channels is discussed, taking into account the optical interference effect. A comparison is made with other access techniques.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Preventive Therapy for Periodontal Diseases (1994)

Rational approaches to the prevention of destructive periodontitis should be based on a clear understanding of etiology and pathogenesis. However, we are dealing with a heterogeneous family of diseases in which different factors operate. It is an oversimplification to regard poor oral hygiene, and hence an accumulation of non-specific dental bacterial plaque, as the major risk factor. Epidemiological evidence indicates that host factors are likely to be of overriding importance for the most severe forms. The limitations of nonspecific plaque control are therefore discussed. Specific inhibitors of virulence factors provide a logical approach, but their clinical application awaits improved knowledge. Improvement of general health and resistance to disease by proper nutrition, the avoidance of intercurrent disease, and elimination of smoking and stress-induced risk are encouraged. The genetic basis of susceptibility to periodontitis is increasingly understood, and, while gene therapy is not likely to be a practicable approach to prevention, genetic markers of risk are emerging.
Activation of related transforming genes in mouse and human mammary carcinomas. (1981)

High molecular weight DNAs of five tumors induced by mouse mammary tumor virus (MMTV), two mouse mammary tumors induced by a chemical carcinogen, and one human mammary tumor cell line (MCF-7) were assayed for the presence of transmissible activated transforming genes by transfection of NIH 3T3 mouse cells. DNAs of all five MMTV-induced tumors, one chemical carcinogen-induced tumor, and the human tumor cell line induced transformation with high efficiencies (approximately 0.2 transformant per micrograms of DNA). NIH cells transformed by DNAs of MMTV-induced tumors did not contain exogenous MMTV DNA sequences, indicating that MMTV-induced mammary carcinomas contained activated cellular transforming genes that were not linked to viral DNA. The transforming activities of DNAs of all five MMTV-induced tumors, the chemical carcinogen-induced mouse tumor, and the human tumor cell line were inactivated by digestion with the restriction endonucleases Pvu II and Sac I, but not by BamHI, EcoRI, HindIII, Kpn I, or Xho I. These results indicate that the same or closely related transforming genes were activated in six different mouse mammary carcinomas, induced by either MMTV or a chemical carcinogen, and in a human mammary carcinoma cell line.
Enantioselective synthesis of 1-substituted tetrahydroisoquinoline-1-carboxylic acids (1992)

The 3,4-dihydroisoquinolinium salt 1 and its enantiomer have been converted readily and stereoselectively into (+)-and (−)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-methylisoquinoline-1-carboxylic acids. The synthetic route described should be applicable to the enantioselective synthesis of a variety of 1-alkyl- or 1-aryl-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acids. The absolute configuration of the amino acid hydrochloride 11 was established to be as depicted in Scheme 2.
Induction of bone marrow stromal cells to neurons: Differentiation, transdifferentiation, or artifact? (2004)

Differentiation of stem cells toward a neuronal lineage normally involves a gradually progressive restriction in developmental potential and is regulated by a diverse set of specific and temporally precise genetic events. However, recent studies have indicated that both rodent and human bone marrow stromal cells (MSCs) can be rapidly (within minutes to hours) induced to differentiate into neurons in vitro by relatively simple chemical means (using beta-mercaptoethanol [BME] or dimethylsulfoxide [DMSO] and butylated hydroxyanisol [BHA]; Woodbury et al. [ 2000] J. Neurosci. Res. 61:364-370). The ability to transdifferentiate an easily accessible cell source into neurons could have substantial potential for promoting neural repair. We therefore explored the potential of simple chemical methods to transdifferentiate other cell types, including primary rat fibroblasts, primary human keratinocytes, HEK293 cells, rat PC-12 cells, and as positive control rat bone marrow stromal (BMS) cells. Surprisingly, all cells except for keratinocytes adopted at least partial "neuron-like" pyramidal cell morphology with fine-cellular extensions resembling neurites upon stimulation with BME or DMSO/BHA. However, time-lapse microscopy indicated that the chemical exposure of MSCs did not result in new neurite growth but rather cellular shrinkage, with retraction of the majority of existing cell extensions, leaving only few, fine neurite-like processes. To determine whether the chemically induced transdifferentiation resulted from simple cellular toxicity, MSCs were exposed to various stressors, including detergents, high-molarity sodium chloride, and extremes of pH. In all cases, cellular shrinkage and adoption of pseudoneuronal morphology were observed. Concomitantly with cellular shrinkage, apparent increases in immunolabeling for the neuronal markers NSE and NeuN were detected in the cell soma that could not be confirmed by RT-PCR. Furthermore, blockade of protein synthesis with cycloheximide did not prevent cells from adopting "neuron-like" morphology after chemical induction. Thus, morphological changes and increases in immunolabeling for certain cellular markers upon "chemical induction" of MSCs are likely the result of cellular toxicity, cell shrinkage, and changes in the cytoskeleton and do not represent regulated steps in a complicated cellular differentiation process.
Energy metabolism and sperm function. (2007)

Energy metabolism is a key factor supporting sperm function. Sustaining sperm motility and active protein modifications such as phosphorylation could be the reason why sperm require exceptionally more ATP than other cells. Many methods have been used to understand the relationship between energy metabolism and sperm function. These approaches have identified critical metabolic pathways that support specific processes during germ cell development and fertilisation. In round spermatids, lactate and pyruvate are the preferred substrates and the use of glucose is limited, however, during epididymal maturation sperm expand to use glycolysis. While the acrosome reaction requires lactate or pyruvate for ATP production by oxidative phosphorylation, gamete fusion requires glucose to produce NADPH by the pentose phosphate pathway. Sperm motility appears to be supported by relatively low ATP levels, but achievement of high ATP levels are essential for tyrosine phosphorylation linked to hyperactivation. Thus, each individual process and event requires a different substrate and metabolic pathway. Despite different preferences for energy substrates and metabolic pathways between species, analysis of knockout mice revealed that glycolysis is indispensable for mouse sperm function and that oxidative phosphorylation is not essential for male fertility. This suggests that glycolysis could compensate for the lack of oxidative phosphorylation and recover most sperm function. Spermatogenic cell-specific glycolytic enzymes may confer flexible use of substrates and adapt to unexpected conditions for substrates in the female reproductive tract.
Performance and power evaluation of a 3D CMOS/nanomaterial reconfigurable architecture (2007)

In this paper, we introduce a novel reconfigurable architecture, named 3D nFPGA, which utilizes 3D integration techniques and new nanoscale materials synergistically. The proposed architecture is based on CMOS-nano hybrid techniques that incorporate nanomaterials such as carbon nanotube bundles and nanowire crossbars into CMOS fabrication process. Using unique features of FPGAs and a novel 3D stacking method enabled by the application of nanomaterials, 3D nFPGA obtains a 4.5X footprint reduction compared to traditional CMOS-based 2D FPGAs. With a customized design automation flow, we evaluate the performance and power of 3D nFPGA driven by the 20 largest MCNC benchmarks. Results demonstrate that 3D nFPGA is able to provide a performance gain of 2.6X with a small power overhead comparing to the CMOS 2D FPGA architecture.
FLUID COATING ON A FIBER (1999)

▪ Abstract We discuss the thickness of the liquid layer entrained by a solid drawn out of a bath, focusing on the case where the solid is a fiber or a wire. Slow withdrawals out of a pure or a complex fluid are described as well as quick coatings. We specify the general laws of entrainment and stress the cases where the fiber curvature plays a role. We finally give an overview on the further evolution of the coated film.
Activation of Immune Function by Dehydroepiandrosterone (DHEA) in Age-Advanced Men (1997)

Administration of oral DHEA at a daily dose of 50 mg to age-advanced men with low serum DHEAS levels significantly activated immune function. The mechanism(s) to account for the immunoenhancing properties of DHEA are unclear. Consideration is given to the potential role of an increase in bioavailable IGF-I, which by virtue of its mitogenic effects on immune cell function, may mediate the DHEA effects. While extended studies are required, our findings suggest potential therapeutic benefits of DHEA in immunodeficient states.
De-anonymizing social graphs via node similarity (2014)

Recently, a number of anonymization algorithms have been developed to protect the privacy of social graph data. However, in order to satisfy higher level of privacy requirements, it is sometimes impossible to maintain sufficient utility. Is it really easy to de-anonymize "lightly" anonymized social graphs? Here "light" anonymization algorithms stand for those algorithms that maintain higher data utility. To answer this question, we proposed a de-anonymization algorithm based on a node similarity measurement. Using the proposed algorithm, we evaluated the privacy risk of several "light" anonymization algorithms on real datasets.
TÜRKİYE`DE RAKET SPORLARI ALANINDA YAPILAN LİSANSÜSTÜ TEZLERİN İNCELENMESİ (2012)

Bu arastirmada ulkemizdeki universitelerde Raket Sporlari alaninda yapilmis olan ve YOK elektronik tez arsivinde yer alan tezler arastirilmistir. Verilerin degerlendirilmesine SPSS paket programi kullanilmistir.Raket sporlari alaninda hazirlanan tezler; yillarina, spor dali, danisman ve konularina gore siniflandirilmistir.Elde edilen veriler tablolar ve grafiklerle gosterilmistir. Sonuc olarak arastirmanin kapsadigi 1990-2010 yillari arasindaki 20 yillik surecte Raket Sporlari alaninda toplam 66 lisansustu tezin yapildigi tespit edilmistir.Bu tezlerden 10`u doktora, 56`si yuksek lisans tezidir.Tezlerin cogunun(n:50 %76) tenis bransinda hazirlandigi gorulmustur.Hareket ve Antrenman bilimleri ise en cok (n:38 %57)calisilan konu olarak tespit edilmistir.
Bactericidal activity of vancomycin, daptomydn, ampicillin and aminoglycosides against vancomycin-resistant Enterococcus faecium (1990)

Daptomycin, vancomycin, ampicillin and aminoglycosides, alone or in combination, were tested for their bactericidal activity against 15 isolates of vancomycin-resistant Enterococcus faecium from immunocompromised children. The kill-kinetic studies at clinically achievable concentrations demonstrated that daptomycin alone or in combination with ampicillin had the greatest bactericidal activity.
Increased Mitochondrial Activity in Anthrax-Induced Cell Death. (2009)

Pathogenesis of anthrax lethal toxin (LT) is attributed to its ability to cause death of infected cells. New work has demonstrated that increase of mitochondrial F1F0 ATPase activity and subsequent depletion of cellular ATP level are critical early events during LT-induced cell death.