gebhart/patrepeval huggingface dataset:
Adaptive predictive text generation and the reactive keyboard (1991)

The paper explores the application of predictive text generation to the human-computer interface. Predictive techniques exploit the statistical redundancy of language to accelerate and amplify user inputs. Acceleration is achieved by making more likely language elements faster to select, while amplification is accomplished by selection of concatenated elements. The language models used are created adaptively, decoupling the prediction mechanism from the application domain and user's vocabulary, and conforming automatically to whatever kind of text is entered. A device called the ‘reactive keyboard’ is described along with two user interface implementations, one for keyboard entry and the other for a mouse/window environment. A clear separation is made between the system's user interface and the underlying model it employs, and the two versions share the same prediction technique and adaptive modelling mechanism. The basic idea is to order context-conditioned candidate strings, which are predicted by the model, according to frequency and display them for selection.
Four novel splice variants of sulfonylurea receptor 1 (2002)

ATP-sensitive K(+) (K(ATP)) channels are composed of pore-forming Kir6.x subunits and regulatory sulfonylurea receptor (SUR) subunits. SURs are ATP-binding cassette proteins with two nucleotide-binding folds (NBFs) and binding sites for sulfonylureas, like glibenclamide, and for channel openers. Here we report the identification and functional characterization of four novel splice forms of guinea pig SUR1. Three splice forms originate from alternative splicing of the region coding for NBF1 and lack exons 17 (SUR1Delta17), 19 (SUR1Delta19), or both (SUR1Delta17Delta19). The fourth (SUR1C) is a COOH-terminal SUR1-fragment formed by exons 31-39 containing the last two transmembrane segments and the COOH terminus of SUR1. RT-PCR analysis showed that these splice forms are expressed in several tissues with strong expression of SUR1C in cardiomyocytes. Confocal microscopy using enhanced green fluorescent protein-tagged SUR or Kir6.x did not provide any evidence for involvement of these splice forms in the mitochondrial K(ATP) channel. Only SUR1 and SUR1Delta17 showed high-affinity binding of glibenclamide (K(d) approximately 2 nM in the presence of 1 mM ATP) and formed functional K(ATP) channels upon coexpression with Kir6.2.
Solder Joint Reliability of BGA, CSP, Flip Chip, and Fine Pitch SMT Assemblies (1996)

Reliability testing and data analysis failure analysis and root cause identification design for reliability solder joint reliability of BGA assemblies solder joint reliability of CSP assemblies solder joint reliability of flip chip assemblies.
Quantification of prolactin receptor mRNA in multiple human tissues and cancer cell lines by real time RT-PCR (2001)

Human prolactin (hPRL) has been reported to be involved in breast and prostate cancer development. The hPRL receptor (hPRLR) is expressed in a wide variety of tissues in at least three isoforms. In this study, a one-step real time reverse transcription PCR technique was used to determine relative expression levels of hPRLR mRNA in eleven human breast cancer cell lines, HeLa cells, three prostate cancer cell lines and nine normal human tissues. The housekeeping gene beta-actin was used for internal normalization. We demonstrate that hPRLR mRNA is up-regulated in six of the eleven breast cancer cell lines tested when compared with normal breast tissue. Of the cancer cell lines tested, we found that T-47D cells have the highest level of hPRLR mRNA, followed by MDA-MB-134, BT-483, BT-474, MCF-7 and MDA-MB-453 cells. In two breast cancer cell lines (MDA-MB-468 and BT-549), the hPRLR levels were found to be comparable to that of normal breast tissue. Three breast cancer cell lines (MDA-MB-436, MDA-MB-157 and MDA-MB-231) expressed hPRLR mRNA at levels lower than that of normal tissue. In contrast, in all three commonly used prostate cancer cell lines (LNCaP, PC-3 and DU 145), the levels of hPRLR mRNA were found to be down-regulated relative to that of normal prostate tissue. Of nine normal human tissues tested, we found that the uterus and the breast have the highest levels of hPRLR mRNA, followed by the kidney, the liver, the prostate and the ovary. The levels of hPRLR mRNA were the lowest among the trachea, the brain and the lung.
Comment on ‘‘Singular-value decomposition and embedding dimension’’ (1988)

In this Comment we consider the conclusion drawn by Mees, Rapp, and Jennings [Phys. Rev. A 36, 340 (1987)] concerning the usefulness of the singular-system analysis of a trajectory matrix (obtained by applying Takens's construction to time-series data). We point out that this is primarily due to their misinterpretation of our work, and to an assumption they apparently made concerning the conditions under which a map preserves the dimension of a set. We attempt to clarify the issues.
Prostate specific antigen detection using AlGaN∕GaN high electron mobility transistors (2007)

Antibody-functionalized Au-gated AlGaN∕GaN high electron mobility transistors (HEMTs) were used to detect prostate specific antigen (PSA). The PSA antibody was anchored to the gate area through the formation of carboxylate succinimdyl ester bonds with immobilized thioglycolic acid. The AlGaN∕GaN HEMT drain-source current showed a rapid response of less than 5s when target PSA in a buffer at clinical concentrations was added to the antibody-immobilized surface. The authors could detect a wide range of concentrations from 10pg∕mlto1μg∕ml. The lowest detectable concentration was two orders of magnitude lower than the cutoff value of PSA measurements for clinical detection of prostate cancer. These results clearly demonstrate the promise of portable electronic biological sensors based on AlGaN∕GaN HEMTs for PSA screening.
Combined speech and audio coding by discrimination (2002)

We propose in this paper a general solution for combined speech and audio coding. Particularly, we describe a speech/music discrimination procedure for multi-mode wideband coding. The speech/music decision is updated only when a low-energy frame is detected, and kept unchanged otherwise. The signal is classified using second-order statistics of discriminant parameters. An experimental CELP/transform coder operating at 16 kbit/s is demonstrated. Results show improved performance when compared to single-mode encoding.
Reduction of Pathological and Behavioral Deficits Following Spinal Cord Contusion Injury with the Selective Cyclooxygenase-2 Inhibitor NS-398 (2001)

Spinal cord injury (SCI) results in loss of locomotor function and development of abnormal chronic pain syndromes (mechanical allodynia, thermal hyperalgesia). Following injury, secondary mechanisms including release of excitatory amino acids, inflammation and lipid peroxidation damage neural cells through release of cytotoxic free radicals. We hypothesized that selective inhibition of cyclooxygenase-2 (COX-2), an inducible inflammatory mediator, would decrease tissue damage and subsequently reduce locomotor deficits and development of chronic central pain syndromes after injury. Fifteen minutes prior to receiving T13 spinal segment spinal cord contusion injury, 200-225-g male Sprague-Dawley rats received either vehicle (0.5 ml 1:1 v/v DMSO/saline, i.p., n = 20) or the selective COX-2 inhibitor NS-398 (5 mg/kg in DMSO/saline v/v, i.p., n = 20). Locomotor function via the BBB scale, and nociceptive behaviors measured by paw withdrawals to von Frey filaments and radiant heat stimuli were tested for 4 weeks postinjury. Histological examination and volumetric analysis of spinal cord tissue were performed concomitantly. Spinally contused animals receiving NS-398 demonstrated significantly (p < 0.05) reduced locomotor alteration and reductions in both fore- and hindlimb mechanical allodynia and thermal hyperalgesia when compared to vehicle controls. Histological examination of spinal segments at the lesion segment demonstrated reduced lesion extent and increased viable tissue when compared to vehicle controls. Prostaglandin E2 levels were significantly lowered in NS-398-treated but not vehicle-treated animals 12 h after injury. These results support the role of COX-2 in reducing pathological and behavioral deficits after spinal cord injury.
802.11 Wireless Networks: The Definitive Guide, Second Edition (2005)

As we all know by now, wireless networks offer many advantages over fixed (or wired) networks. Foremost on that list is mobility, since going wireless frees you from the tether of an Ethernet cable at a desk. But that's just the tip of the cable-free iceberg. Wireless networks are also more flexible, faster and easier for you to use, and more affordable to deploy and maintain. The de facto standard for wireless networking is the 802.11 protocol, which includes Wi-Fi (the wireless standard known as 802.11b) and its faster cousin, 802.11g. With easy-to-install 802.11 network hardware available everywhere you turn, the choice seems simple, and many people dive into wireless computing with less thought and planning than they'd give to a wired network. But it's wise to be familiar with both the capabilities and risks associated with the 802.11 protocols. And 802.11 Wireless Networks: The Definitive Guide, 2nd Edition is the perfect place to start. This updated edition covers everything you'll ever need to know about wireless technology. Designed with the system administrator or serious home user in mind, it's a no-nonsense guide for setting up 802.11 on Windows and Linux. Among the wide range of topics covered are discussions on: deployment considerationsnetwork monitoring and performance tuningwireless security issueshow to use and select access pointsnetwork monitoring essentialswireless card configurationsecurity issues unique to wireless networks With wireless technology, the advantages to its users are indeed plentiful. Companies no longer have to deal with the hassle and expense of wiring buildings, and households with several computers can avoid fights over who's online. And now, with 802.11 Wireless Networks: The Definitive Guide, 2nd Edition, you can integrate wireless technology into your current infrastructure with the utmost confidence.
Overexpression of the Cell Adhesion Molecules DDR1, Claudin 3, and Ep-CAM in Metaplastic Ovarian Epithelium and Ovarian Cancer (2004)

These results suggest that up-regulation of DDR1, CLDN3, and epithelial cell adhesion molecule are early events in the development of EOC and have potential application in the early detection of disease.
Therapeutic myocardial angiogenesis using percutaneous intrapericardial drug delivery (1999)

In this manuscript, we describe the potential role of the pericardial space as a drug delivery reservoir to administer angiogenic agents to the heart resulting in functionally significant angiogenesis with single bolus basic fibroblast growth factor (bFGF) delivery. We also describe a percutaneous subxyphoid pericardial access technique that is safe, rapid, and reliable.
Composite document extended retrieval (1985)

Experimental information retrieval (IR) systems, some dating back to the sixties, have demonstrated the viability of fully automatic document storage and retrieval methodologies with small to medium size bibliographic collections [72]. Many of these experimental systems utilize the vector space model in which each important term (such as a word stem) identifies a different dimension in a space, so that matrix methods and vector operations can be defined on queries and documents. Statistical techniques have been very effective, and probabilistic enhancements have given additional improvements [84]. However, the basic vector space model is oriented towards recording the essential information in the text of a title/abstract combination rather than describing more complex document structures. It is necessary to extend the model in order to handle composite documents.
Synthesis and characterization of chemically bonded stationary phases on hydride surfaces by hydrosilation of alkynes and dienes (2005)

A hydrosilation reaction was used to bind four compounds with one or more alkyne groups or two alkene functionalities. The diffuse reflectance infrared Fourier transform, the 29Si cross-polarization magic-angle spinning (CP-MAS) NMR, and the 13C CP-MAS NMR spectra were used to characterize the various bonded materials. The bonded phase density was determined from carbon elemental analysis. The two ten-carbon hydrophobic stationary phases were characterized chromatographically and static stability tests were run in acidic and basic solutions.
Expression and characterization of a multivalent human respiratory syncytial virus protein (2010)

Respiratory syncytial virus (RSV) has been recognized as one of the most common causes of severe respiratory tract infection in infants worldwide. As yet, a safe and effective vaccine has not been developed to protect humans from RSV. The F and G surface proteins have been widely investigated due to their potential to induce protective immunity. In addition, the M2 protein has been shown to be important in inducing a T-cell response. Our project involved the cloning of the immunodominant regions of the RSV F, M2 and G proteins into a bacterial vector, pET-32a (+). The recombinant RFM2G protein was expressed in Escherichia coli and purified using His Bind columns. The purified rRFM2G protein was analyzed by polyacrylamide gel electrophoresis and Western blotting. The predicted structure of the recombinant protein built by the Swiss PDB Viewer program suggested a rod shape with a distinct swollen head and neck which was confirmed by transmission electron microscopy and atomic force microscopy. BALB/c female mice were immunized with either RSV, rRFM2G alone, or rRFM2G in combination with flagellin as a mucosal adjuvant. Serum was collected on days 0, 14, 28 and 49 to assess the immune response by Enzyme-linked immunosorbent assay. Intranasal immunization of mice with the rRFM2G protein yielded significantly high serum IgG titers. Co-administration of the rRFM2G protein with flagellin did not augment the serum antibody response.
Automatic Projector Calibration Using Self-Identifying Patterns (2006)

Calibrating multiple monitor or projector display elements to provide a composite image can be a time-consuming task if performed manually. Ideally the user would like to roughly aim a number of projectors at a surface, define the desired display corners, and have some automatic method to align the display. A digital camera and computer vision can be used to calibrate the projectors with the assistance of self-identifying patterns. To account for distortion effects and to equalize brightness, it is desirable to know the mapping of many points within each projector image. A small set of images can be projected from each display element if a self-identifying pattern is used. An array of ARTag markers are used as a self-identifying pattern which is displayed in turn by each of the display monitors or projectors and recognized in the camera image. In this way an ad-hoc arrangement of projectors can be calibrated in seconds. Experimental results are shown validating this architecture.
From deoxynucleotides to DNA synthesis. (1978)

The deoxyribonucleotides required for DNA synthesis are provided by reduction of ribonucleotides. Our studies aim at an understanding of the interplay between the processes involved in the production of deoxyribonucleotides and in their consumption. The enzyme system reducing ribonucleotides has been characterized in some detail, and its regulatory aspects were investigated with pure enzymes. Knowledge gained in this way made it possible to interfere specifically with the activity of ribonucleotide reductase in intact cells and to study effects on DNA synthesis. In this connection, the replication of polyoma DNA was used as a model that allowed dissection of DNA synthesis into different steps involved in the initiation and elongation processes.
3D Retrieval System based on Cognitive Level (2004)

This paper shows a media-linkage method on cognitive level based on adjective annotation method. The method consists of mapping from still-images and 3D models to adjective texts because adjective texts as a cognitive level can be used for different multimedia data to link texts, images, 3D object models, etc. The method automatically obtains adjective scores and labels adjective texts for all the images and 3D models in the database. To construct the mapping, we have analyzed the relationship between adjectives and graphical parameters of not only street images but also 3D building models. We set up a pilot study to find 3D buildings from the database in a street image of Minato Mirai 21 (Yokohama) by using the media-linkage method.
A study on speaker adaptation of the parameters of continuous density hidden Markov models (1991)

For a speech-recognition system based on continuous-density hidden Markov models (CDHMM), speaker adaptation of the parameters of CDHMM is formulated as a Bayesian learning procedure. A speaker adaptation procedure which is easily integrated into the segmental k-means training procedure for obtaining adaptive estimates of the CDHMM parameters is presented. Some results for adapting both the mean and the diagonal covariance matrix of the Gaussian state observation densities of a CDHMM are reported. The results from tests on a 39-word English alpha-digit vocabulary in isolated word mode indicate that the speaker adaptation procedure achieves the same level of performance as that of a speaker-independent system, when one training token from each word is used to perform speaker adaptation. It shows that much better performance is achieved when two or more training tokens are used for speaker adaptation. When compared with the speaker-dependent system, it is found that the performance of speaker adaptation is always equal to or better than that of speaker-dependent training using the same amount of training data.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Information transfer from DNA to peptide nucleic acids by template- directed syntheses (1997)

Peptide nucleic acids (PNAs) are analogs of nucleic acids in which the ribose-phosphate backbone is replaced by a backbone held together by amide bonds. PNAs are interesting as models of alternative genetic systems because they form potentially informational base paired helical structures. Oligocytidylates have been shown to act as templates for formation of longer oligomers of G from PNA G2 dimers. In this paper we show that information can be transferred from DNA to PNA. DNA C4T2C4 is an efficient template for synthesis of PNA G4A2G4 using G2 and A2 units as substrates. The corresponding synthesis of PNA G4C2G4 on DNA C4G2C4 is less efficient. Incorporation of PNA T2 into PNA products on DNA C4A2C4 is the least efficient of the three reactions. These results, obtained using PNA dimers as substrates, parallel those obtained using monomeric activated nucleotides.
Data-driven modeling of skin and muscle deformation (2008)

In this paper, we present a data-driven technique for synthesizing skin deformation from skeletal motion. We first create a database of dynamic skin deformations by recording the motion of the surface of the skin with a very large set of motion capture markers. We then build a statistical model of the deformations by dividing them into two parts: static and dynamic. Static deformations are modeled as a function of pose. Dynamic deformations are caused by the actions of the muscles as they move the joints and the inertia of muscles and fat. We approximate these effects by fitting a set of dynamic equations to the pre-recorded data. We demonstrate the viability of this approach by generating skin deformations from the skeletal motion of an actor. We compare the generated animation both to synchronized video of the actor and to ground truth animation created directly from the large marker set.
Emulating short-term synaptic dynamics with memristive devices (2016)

Neuromorphic architectures offer great promise for achieving computation capacities beyond conventional Von Neumann machines. The essential elements for achieving this vision are highly scalable synaptic mimics that do not undermine biological fidelity. Here we demonstrate that single solid-state TiO2 memristors can exhibit non-associative plasticity phenomena observed in biological synapses, supported by their metastable memory state transition properties. We show that, contrary to conventional uses of solid-state memory, the existence of rate-limiting volatility is a key feature for capturing short-term synaptic dynamics. We also show how the temporal dynamics of our prototypes can be exploited to implement spatio-temporal computation, demonstrating the memristors full potential for building biophysically realistic neural processing systems.
Regression of established tumors and metastases by potent vascular endothelial growth factor blockade (2003)

Vascular endothelial growth factor (VEGF) is a critical promoter of blood vessel growth during embryonic development and tumorigenesis. To date, studies of VEGF antagonists have primarily focused on halting progression in models of minimal residual cancer. Consistent with this focus, recent clinical trials suggest that blockade of VEGF may impede cancer progression, presumably by preventing neoangiogenesis. However, VEGF is also a key mediator of endothelial-vascular mural cell interactions, a role that may contribute to the integrity of mature vessels in advanced tumors. Here, we report that high-affinity blockade of VEGF, using the recently described VEGF-Trap, abolishes mature, preexisting vasculature in established xenografts. Eradication of vasculature is followed by marked tumor regression, including regression of lung micrometastases. Thus, the contribution of relatively low levels of VEGF to vessel integrity may be critical to maintenance of even very small tumor masses. Potent blockade of VEGF may provide a new therapeutic option for patients with bulky, metastatic cancers.
Mink Lung Cells and Mixed Mink Lung and A549 Cells for Rapid Detection of Influenza Virus and Other Respiratory Viruses (2000)

Mink lung cells were more sensitive than the commonly used MDCK or pRhMK cells for rapid detection of influenza virus A from clinical specimens. Mixed Mv1Lu and A549 cells in a single shell vial were synergistic for detection of influenza virus A and were as sensitive as individual cells for detection of other respiratory viruses.
Fetal ECG extraction from single-channel maternal ECG using singular value decomposition (1997)

The extraction of fetal electrocardiogram (ECG) from the composite maternal ECG signal obtained from the abdominal lead is discussed. The proposed method employs singular value decomposition (SVD) and analysis based on the singular value ratio (SVR) spectrum. The maternal ECG (M-ECG) and the fetal ECG (F-ECG) components are identified in terms of the SV-decomposed modes of the appropriately configured data matrices, and elimination of the M-ECG and determination of F-ECG are achieved through selective separation of the SV-decomposed components. The unique feature of the method is that only one composite maternal ECG signal is required to determine the F-ECG component. The method is numerically robust and computationally efficient.