gebhart/patrepeval huggingface dataset:
Context Contrasted Feature and Gated Multi-scale Aggregation for Scene Segmentation (2018)

Scene segmentation is a challenging task as it need label every pixel in the image. It is crucial to exploit discriminative context and aggregate multi-scale features to achieve better segmentation. In this paper, we first propose a novel context contrasted local feature that not only leverages the informative context but also spotlights the local information in contrast to the context. The proposed context contrasted local feature greatly improves the parsing performance, especially for inconspicuous objects and background stuff. Furthermore, we propose a scheme of gated sum to selectively aggregate multi-scale features for each spatial position. The gates in this scheme control the information flow of different scale features. Their values are generated from the testing image by the proposed network learnt from the training data so that they are adaptive not only to the training data, but also to the specific testing image. Without bells and whistles, the proposed approach achieves the state-of-the-arts consistently on the three popular scene segmentation datasets, Pascal Context, SUN-RGBD and COCO Stuff.
Preparation of Co1−zAlz(OH)2(NO3)z Layered Double Hydroxides and Li(Co1−zAlz)O2 (2008)

The precipitate formed by the addition of an aqueous solution of Co(NO3)2 and Al(NO3)3 to LiOH solution has been thoroughly studied as a function of the Al:(Al+Co) ratio, z, for 0 ≤ z ≤ 1, using X-ray diffraction and thermogravimetric analysis. For 0 ≤ z ≤ 0.2, the precipitate was a mixed phase of Co(OH)2 and the layered double hydroxide (LDH) Co0.8Al0.2(OH)2(NO3)0.2·nH2O. For 0.2 ≤ z ≤ 0.4 the precipitate was a single LDH phase containing both NO3− and CO32− ions to compensate the Al3+ charge. As z increases in this range, the amount of NO3− decreases and the amount of CO32− increases. For z > 0.4, the precipitate was a two phase mixture of an LDH phase and Al(OH)3. Li[Co1−zAlz]O2 samples were made from the coprecipitated products for 0 ≤ z ≤ 0.5, by calcining the coprecipitate and Li2CO3. These Li[Co1−zAlz]O2 samples were compared to samples of the same stoichiometries made by the direct solid state reaction of Co3O4, Al(OH)3, and Li2CO3. The lattice constants varied smoothly with z for the Li[Co1−zAlz]O2 samples made from the coprecipitate. The lattice constants of the solid-state samples deviate from these for z > 0.15, suggesting the Al is not uniformly incorporated for z > 0.15 in the solid-state samples. The consequences of this are discussed.
Anti-intercellular substance antibody log titres are correlated with serum concentrations of interleukin-6, interleukin-15 and tumor necrosis factor-alpha in patients with Pemphigus vulgaris relationships with peripheral blood neutrophil counts, disease severity and duration and patients' age. (2000)

Pemphigus vulgaris is a rare dermatosis of autoimmune origin, characterized by autoantibodies directed against intercellular substance (AICS) and presenting with intra-epidermal blisters and/or erosions of the skin and mucous membranes. The aim of this paper is to analyze the relationships between serum AICS titers (after log transformation) and: patients' age, disease duration and disease activity; serum cytokine (IL-6, IL-7, IL-15 and TNF-alpha) concentrations and peripheral blood cell counts (namely neutrophils, lymphocytes and natural killer cells). Fifteen consecutive subjects affected with PV were enrolled. Diagnosis was supported by histological examination as well as by direct and indirect immunofluorescence tests. Cytokine determinations were made by means of commercially available ELISA kits. This study shows for the first time that AICS titers have a significant correlation with age of PV patients (R=0.57, p=0.031) and with the disease duration (R=0.73, p=0.002). A correlation between blood neutrophils count and log (AICS) titres was observed (R=0.6, p=0.021). Furthermore, significant correlations were observed between log (AICS) titres and serum IL-15 (R=0.54, p=0.048), serum IL-6 (R=0.53, p=0.05) or serum TNF-alpha concentrations (R=0.53, p=0.05). These data, taken together, show that there are several connections between the log (AICS) titres, some proinflammatory cytokines, peripheral blood neutrophil counts and the numbers of individuals' lesions, suggesting a relationship between AICS production and lesion development.
ASCENT OF QUADRUPLEXES (2007)

RETURN TO ISSUEPREVNewsNEXTASCENT OF QUADRUPLEXESNucleic acid structures become promising DRUG TARGETSCite this: Chem. Eng. News 2007, 85, 22, 12–17Publication Date (Print):May 28, 2007Publication History Published online29 October 2010Published inissue 28 May 2007https://doi.org/10.1021/cen-v085n022.p012Copyright © 2007 AMERICAN CHEMICAL SOCIETYArticle Views21Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (4 MB) SUBJECTS:Chemical structure,Genetics,Guanine Get e-Alerts
All-solid photonic bandgap fiber (2004)

We describe the design and fabrication of a photonic bandgap fiber formed with two different glasses. As in a hollow-core fiber, light is guided in a low-index core region because of the antiresonances of the high-index strands in the fiber cladding. The structure described represents an ideal bandgap fiber that exhibits no interface modes and guides over the full width of multiple bandgaps.
Cartilage grafts—present status (1986)

Cartilage grafts have been in use for almost a century and have proved their usefulness. Many questions about immunology, survival, growth, and role of perichondrium are still debated. We are presenting a review of the literature and of our experimental work on cartilage grafts. Ear cartilage was transplanted from 28 young New Zealand rabbits subcutaneously in the chest walls. The grafts were divided into 1) bare cartilage, 2) perichondrium, 3) cartilage covered with perichondrium on one side, and 4) cartilage covered with perichondrium on both sides. The grafts were measured in length and weight before transplantation, and at 2 and 4 months after transplantation; they were compared to a control piece of cartilage tagged in situ. Histologic examination was performed on all retrieved grafts. Transplanted cartilage survival was good in over 75% of cases; however, cartilage production from perichondrium was minimal and no growth was noticed in any of the grafts.
Recent Approaches to Dialog Management for Spoken Dialog Systems (2010)

A field of spoken dialog systems is a rapidly growing research area because the performance improvement of speech technologies motivates the possibility of building systems that a human can easily operate in order to access useful information via spoken languages. Among the components in a spoken dialog system, the dialog management plays major roles such as discourse analysis, database access, error handling, and system action prediction. This survey covers design issues and recent approaches to the dialog management techniques for modeling the dialogs. We also explain the user simulation techniques for automatic evaluation of spoken dialog systems.
Direct In Vivo Visualization of Intravascular Destruction of Microbubbles by Ultrasound and its Local Effects on Tissue (1998)

Microbubbles can be destroyed by ultrasound, resulting in a bioeffect that could be used for local drug delivery, angiogenesis, and vascular remodeling, or for tumor destruction.
Antibodies with Infinite Affinity:  Origins and Applications (2006)

Antibodies with infinite affinity were developed with the aim of improving targeted delivery of metal complexes to sites of disease. This is part of a series of chemical technology developments for biomedical imaging and therapy. Using a combination of genetics and chemical synthesis, it addresses challenges in developing proteins that specifically bind synthetic molecules and do not release them. The result is a set of reagents that promise to capture any of a large variety of metallic elements under physiological conditions and hold them for long periods of time.
Synthesis of iron(ii), manganese(ii) cobalt(ii) and ruthenium(ii) complexes containing tridentate nitrogen ligands and their application in the catalytic oxidation of alkanes (2005)

A series of Fe(II), Mn(II), Co(II) and Ru(II) complexes containing bis(imino)pyridine or bis(amino)pyridine ligands and weakly coordinating triflate (OTf-) or non-coordinating SbF6- anions have been prepared. The complexes have been fully characterized including several solid-state structure analyses. Two unusual mono-chelate six-coordinate bis(imino)pyridine Fe(II) and Mn(II) complexes have been observed. The catalytic properties of the complexes for the oxidation of cyclohexane with H2O2 have been evaluated. Only the Fe(II) complexes have shown catalytic activity, which is mainly due to Fenton-type free radical auto-oxidation.
Delayed decision-feedback sequence estimation (1989)

The authors delayed-decision-feedback sequence estimation (DDFSE) for uncoded PAM signals is considered. Estimates on the performance of the algorithm are given, and simulation results are provided for several examples. A more general form of DDFSE applicable to coded modulation systems is also presented. As an example, detection of trellis-coded QPSK (quadrature phase-shift keyed) signals over intersymbol interference channels is discussed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Surface Acoustic Wave Devices for Mobile and Wireless Communications (1998)

Fundamentals of Surface Acoustic Waves and Devices: Introduction. Basics of Piezoelectricity and Acoustic Waves. Principles of Linear Phase SAW Filter Design. Equivalent Circuit and Analytic Models for a SAW Filter. SomeMatching and Trade-Off Concepts for SAW Filter Design. Compensation for Second-Order Effects in SAW Filters. Designing SAW Filters for Arbitrary Amplitude/Phase Response. Interdigital Transducers with Chirped or Slanted Fingers. IDT Finger Reflections andRadiation Conductance. Techniques, Devices and Mobile/Wireless Applications: Overview of Systems and Devices. SAW Reflection Gratings and Resonators. Single-Phase Unidirectional Transducers for Low-Loss Filters. RF and Antenna-Duplexer Filters forMobile/Wireless Transceivers. Other RF Front-end and Inter-stage Filters for Mobile/Wireless Transceivers. SAW IF Filters for Mobile Phones and Pagers. Fixed-Code SAW IDTs for Spread-Spectrum Communications. Real-Time SAW Convolvers for Voice and Data Spread-Spectrum Communications. Surface Wave Oscillators and Frequency Synthesizers. SAW Filters for Digital Microwave Radio, Fiber Optic, and Satellite Systems. Postscript. Subject Index.
Molecular cloning and expression of RPE65, a novel retinal pigment epithelium-specific microsomal protein that is post-transcriptionally regulated in vitro (1993)

Studies reported previously from this laboratory have shown that microsomal membranes of the vertebrate retinal pigment epithelium (RPE) contain an RPE-specific 65-kDa protein, RPE65, which bears the determinant recognized by the strictly tissue-specific monoclonal antibody RPE9, and which is developmentally regulated (Hamel, C. P., Tsilou, E., Harris, E., Pfeffer, B. A., Hooks, J. J., Detrick, B., and Redmond, T. M. (1993) J. Neurosci. Res. 34, 414-425). Microsequencing of 17 tryptic and chymotryptic peptides obtained from the in situ digestion of the RPE65 blotted on nitrocellulose yielded primary sequences that were used to generate oligonucleotide probes. An 84-nucleotide guessmer was used to isolate two clones from a bovine RPE lambda Zap II cDNA library. Rapid amplification of cDNA ends was used to complete the 5' and 3' ends, resulting in a 3,115-base pair composite cDNA. The open reading frame encodes a novel protein of 533 amino acid residues with a computed molecular weight of 60,940. This protein does not match any other sequence in the data bases. The 231 amino acids obtained from peptide sequencing match 43% of the amino acid sequence deduced from the cDNA. The protein has a calculated pI of 6.41 and is not predicted to have any transmembrane segments. The open reading frame expressed in Escherichia coli has an apparent molecular weight identical to that of the native protein and is recognized by the monoclonal antibody RPE9, further corroborating its validity. Northern blot analysis detected a major mRNA species of 3.15 kilobases for RPE65, as well as shorter species, only in RPE and not in other tissues (including other ocular tissues). Cultured RPE cells (7 weeks in primary culture) contained RPE65 mRNA in amounts equivalent to fresh RPE. Such cells, however, contained no immunodetectable RPE65. The possible structure of this RPE-specific protein and hypotheses for the absence of translation in vitro are discussed.
Sorting Peanuts by Pod Density to Improve Quality and Kernel Maturity Distribution and to Reduce Aflatoxin1 (1994)

Abstract Peanut maturity and several peanut quality factors are closely related. An examination of peanut physical properties revealed that by sorting farmer-stock peanuts into pod density classes before shelling, the maturity distributions within shelled-stock classes can be manipulated. An unsorted sample of farmer-stock peanut having an initial maturity distribution in No. 1 kernels of 66% immature, 23% mid-mature and 11% mature was sorted using a gravity separator into four pod-density fractions ranging from 98% immature and 2% mid-mature in the least dense fraction to 8% immature, 43% mid-mature and 49% mature in the most dense fraction. Along with improvements in maturity distributions, we also found that the higher test weight fractions (higher pod density) had less aflatoxin and a greater percentage of large kernels than did the low test weight fractions. Many density sorting devices were tested, including air columns, pod cleaners, and gravity tables. All of these devices were capable of sorting pods into maturity groups, but the gravity table was the most precise.
ChemInform Abstract: CYCLOPHOSPHATES. III. SYNTHESIS AND PROPERTIES OF URIDINE 3′,5′‐CYCLOPHOSPHATE ESTERS (1977)

Abstract Die Uridincyclophosphate (I) werden mit den Diazoverbindungen (II) zu den Estern (III) alkyliert"; als Nebenreaktioneqspeziell bei höherem pH, tritt hauptsächlich mit CH 3 ‐CHN" weniger mit CH,N, und fast nicht mit CöHs‐CHN, eine Alkylierung des Uridins am N‐3 ein.
A 6‐Month Controlled Naltrexone Study: Combined Effect With Cognitive Behavioral Therapy in Outpatient Treatment of Alcohol Dependence (2003)

This study supports the effect of naltrexone in outpatient treatment of alcohol dependence and suggests that a beneficial interaction effect with CBT can be expected.
High Temperature Compatibility Issues for Fusion Reactor Structural Materials (2003)

The primary functions of the blanket in a deuterium/tritium-fueled fusion reactor are to convert neutron kinetic energy into heat, breed tritium for the fuel cycle and accommodate a heat transfer system. Various blanket concepts have been considered including those incorporating liquid metals, molten salts, water and He. The objective of this review is to outline some of the critical compatibility issues associated with structural materials being considered for designs operating at >500°C. Examples are given for vanadium alloys, magnetohydrodynamic coatings, oxide dispersion strengthened ferritic alloys and silicon carbide composites.
Terahertz-wave surface-emitted difference frequency generation in slant-stripe-type periodically poled LiNbO3 crystal (2002)

We demonstrate terahertz-wave (THz-wave) surface-emitted difference frequency generation with nanosecond pulse duration. A slant-stripe-type periodically poled lithium niobate (PPLN) crystal was used to realize the quasi-phase-matching in two mutually perpendicular directions of optical and THz-wave propagation. A THz-wave with a wavelength near 200 μm was generated by mixing the radiation of a dual-signal-wave optical parametric oscillator based on a periodically phase-reversed PPLN crystal.
Cancer-specific mutations in PIK3CA are oncogenic in vivo (2006)

The PIK3CA gene, coding for the catalytic subunit p110alpha of class IA phosphatidylinositol 3-kinases (PI3Ks), is frequently mutated in human cancer. Mutated p110alpha proteins show a gain of enzymatic function in vitro and are oncogenic in cell culture. Here, we show that three prevalent mutants of p110alpha, E542K, E545K, and H1047R, are oncogenic in vivo. They induce tumors in the chorioallantoic membrane of the chicken embryo and cause hemangiosarcomas in the animal. These tumors are marked by increased angiogenesis and an activation of the Akt pathway. The target of rapamycin inhibitor RAD001 blocks tumor growth induced by the H1047R p110alpha mutant. The in vivo oncogenicity of PIK3CA mutants in an avian species strongly suggests a critical role for these mutated proteins in human malignancies.
MobiDesk (2004)

We present MobiDesk, a mobile virtual desktop computing hosting infrastructure that leverages continued improvements in network speed, cost, and ubiquity to address the complexity, cost, and mobility limitations of today's personal computing infrastructure. MobiDesk transparently virtualizes a user's computing session by abstracting underlying system resources in three key areas: display, operating system, and network. It provides a thin virtualization layer that decouples a user's computing session from any particular end-user device, and moves all application logic to hosting providers. The virtualization layer decouples a user's computing session from the underlying operating system and server instance, enabling high-availability service by transparently migrating sessions from one server to another during server maintenance or upgrades. We have implemented a prototype in Linux that works with existing unmodified applications and operating system kernels. Our experimental results demonstrate that MobiDesk has very low virtualization overhead, can provide a full featured desktop experience including full-motion video support, and is able to migrate users' sessions efficiently and reliably for high-availability, while maintaining existing network connections.
Inhibitors of Nitric Oxide Production from Hops (Humulus lupulus L.). (2003)

Nitric oxide (NO) plays an important role in many inflammatory responses and is also involved in carcinogenesis. In the present study, we investigated the inhibitory effect of extracts from Humulus lupulus L. on both the production of NO and the expression of inducible NO synthase (iNOS) in mouse macrophage RAW 264.7 cells. The production of NO was induced by a combination of lipopolysaccharide (LPS) and IFN-gamma, and determined by Griess assay. The expression of iNOS was detected by Western blotting. The LPS/IFN-gamma-induced production of NO and expression of iNOS were significantly inhibited by the ethyl acetate soluble fraction of Humulus lupulus L. Through bioactivity guided fractionation, humulene, five chalcones, 2,2-di-(3-methyl-2-butyleyl)-4,5-dihydoxy-cyclopent-4-en-1,3-dione, lupulone and three of its derivatives were isolated from the ethyl acetate soluble fraction. The chalcones, including xanthohumol, significantly inhibited the production of NO by suppressing the expression of iNOS.
Annexin V Inhibition of Factor IXa-Catalyzed Factor X Activation on Human Platelets and on Negatively-Charged Phospholipid Vesicles (1996)

Annexin V was found to inhibit factor IXa-catalyzed factor X activation on both thrombin-activated human platelets and artificial lipid vesicles containing phosphatidylserine, supporting previous observations of the importance of negatively-charged lipid in potentiating the reaction. Annexin V reduced the Vmax of factor X activation in factor IXa titrations on the platelet surface with an IC50 of 4 nM in the absence of thrombin-activated factor VIII (factor VIIIa), and 4.5 nM in its presence, whereas there was no effect on the EC50,FIXa. This noncompetitive inhibition is consistent with interference of recognition of the factor IXa binding site on the platelet, which was confirmed by equilibrium binding of [125I]-factor IXa to thrombin-activated platelets where, in the absence of factor VIIIa and factor X, annexin V reduced the number of factor IXa binding sites/platelet from 610 to 320, without changing the Kd,app. In the presence of factor VIIIa and factor X, annexin V reduced the number of binding sites, but also raised the Kd,app. Although factor VIIIa improved the affinity of factor IXa for the lipid surface from Kd approximately 60 nM in its absence to Kd 1 nM in its presence, addition of annexin V to factor IXa titrations on lipid vesicles in the presence of factor VIIIa increased the EC50,FIXa with an IC50 of 1.5 nM, without affecting the Vmax. These data provide evidence that factor IXa, although requiring negatively-charged phospholipid for part of its binding site, is accommodated differently on platelets and on artificial vesicles.
Cholesterol binding at the cholesterol recognition/ interaction amino acid consensus (CRAC) of the peripheral-type benzodiazepine receptor and inhibition of steroidogenesis by an HIV TAT-CRAC peptide (2001)

We previously defined a cholesterol recognition/interaction amino acid consensus (CRAC; ATVLNYYVWRDNS) in the carboxyl terminus of the peripheral-type benzodiazepine receptor (PBR), an outer mitochondrial membrane protein involved in the regulation of cholesterol transport into the mitochondria, the rate-determining step in steroid biosynthesis. We examined (i) the PBR-cholesterol interaction by UV crosslinking of the C17 side-chain containing progestin, promegestone, and (ii) the role of the CRAC domain of PBR in Leydig cell steroidogenesis by using a transducible peptide composed of the TAT domain of HIV and the CRAC domain of PBR. [(3)H]Promegestone photoincorporated into recombinant PBR, and this labeling was displaced by cholesterol. [(3)H]Promegestone also photoincorporated into the TAT-CRAC peptide. [(3)H]Promegestone crosslinking to TAT-CRAC could be displaced by cholesterol and promegestone, with IC50 values of 1 and 200 microM, respectively. TAT-CRAC efficiently transduced into MA-10 Leydig cells and inhibited the hCG- and cAMP-stimulated steroid production in a dose-dependent manner. TAT-CRAC did not affect the hCG-induced cAMP synthesis and the 22R-hydroxycholesterol-supported steroidogenesis. Mutated TAT-CRAC lost its ability to bind [(3)H]promegestone and to inhibit the hCG-stimulated steroidogenesis. These results show that TAT-CRAC binds cholesterol and competes for cholesterol interaction with endogenous PBR, suggesting that the cytosolic carboxyl-terminal domain of PBR is responsible for taking up and bringing steroidogenic cholesterol into the mitochondria.
Comparative Analysis of the 16S rRNA Gene Sequence of the Putative Agent of Proliferative Ileitis of Hamsters (1994)

Proliferative ileitis of hamsters is consistently associated with the presence of intracellular bacteria in affected ileal epithelial cells. The 16S rRNA gene sequence of the putative etiologic agent of proliferative ileitis was determined by using cell culture-maintained organisms. The highest level of relatedness (98.4%) was observed with a newly described obligately intracellular bacterium obtained from porcine intestines, and the level of homology with Desulfovibrio desulfuricans was 87.5%.