gebhart/patrepeval huggingface dataset:
Improving stereotactic surgery using 3-D reconstruction (2002)

In brain surgery, placing a microelectrode from the outer brain to the specific target becomes a new medical resource-reduced technology to alleviate Parkinson's disease. During the operation, the brain atlas is an important and auxiliary tool that cannot completely describe the real brain structure of the patient. Thus, a neurosurgeon usually conjectures the surgical target through experience under the condition that no individual brain atlas is available. Hence, the danger of the surgical operation is high and the automation of the whole process is hard to achieve. In this article, we utilize the patient's computed tomography (CT) data, Schaltenbrand-Wahren (SW) brain atlas, and image processing techniques to develop a novel stereotactic surgical planning system, named Brain Deep Tracer. This system can help a neurosurgeon perform minimally invasive brain surgery (e.g., functional stereotaxy) and diagnose brain disease such as Parkinson's. Generally speaking, this system includes versatile functions such as three-dimensional (3-D) reconstruction of the brain atlas, 3-D localization of the patient's brain CT data, registration of the brain atlas and CT data, fusion of the brain atlas and CT data, and surgical trajectory planning. More importantly, this system can correct the distortion due to the tilt of the head frame and make the localization result more accurate than other systems.
A description model of video content and its application for video structuring (1996)

Abstract A method has been investigated in which the video content description is handled by a computer and is applied to the video database, as a means of desktop video production. In the course of video production, it often happens that the description of the interpretation of the video content by the video producer is retained in the form of a document. Such a description is considered most important to describe the video, but there have been only a few efforts at handling the description by electronic means. This paper proposes a method to analyze the description style of the scenario or the raw memorandum by the on‐site producer, and the corresponding video component scene description model is constructed. The application to the video database is discussed, in order to demonstrate the usefulness of the model. An experiment to extract the layered structure is presented using the video in the actual broadcast program. The effectiveness of the structurization technique and the feasibility of the application of the descriptive model to the video database are demonstrated. An experimentally constructed video browser is also discussed.
Influence of steel casings on electromagnetic signals (1994)

Abstract Most wells in oil fields are cased with metal. The feasibility of measuring low-frequency magnetic fields through such steel-cased wells is of great interest for monitoring fluid movement during production. We report on experimental and modeling results regarding the effect of steel casing on electromagnetic signals transmitted through them. This effect includes the attenuation and phase shift of a signal diffusing through the casing wall. Sample casings are studied under low field strength in the linear regime where the casing's electrical properties are independent of the applied signals. Frequency spectra are measured for transverse-electric and transverse-magnetic polarizations from 0.1 Hz to 1 kHz. Numerical models, developed to simulate the casing response, match the experimental data very well. Finally, studies of the effects of the earth's magnetic field and casing remanent magnetization show that these steady biases do not affect the ac signal detection.
Prediction of Prostate Cancer for Patients Receiving Finasteride: Results From the Prostate Cancer Prevention Trial (2007)

Risk factors for prostate cancer on biopsy for men receiving finasteride include PSA, DRE, age, race, family history, and history of a prior negative biopsy. With the exception of the approximate reduction of PSA by half with finasteride, the impact of these risk factors is similar to men who do not receive finasteride.
Encoding strategies in combinatorial chemistry (1997)

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences.
Online Payment - Innovation in Split Tender Payment (2012)

Online Payment is the fastest and secured way of making payments for various purposes like making utility payments, transferring funds and making purchases online. This paper will help to uncover few important value adding features in Split tender payment method which will increase the utility and make it user friendly.
<i>CalcTav</i>—integration of a spreadsheet and <i>Taverna</i> workbench (2011)

sroka@mimuw.edu.pl.
Conservatism, Dogmatism, and Authoritarianism in British Police Officers (1982)

The Wilson-Patterson Attitude Inventory, Eysenck's Social and Political Attitude Inventory, Rokeach's Dogmatism Scale, and the Lee-Warr Balanced F Scale were administered to 48 recruit police constables at the beginning and end of their basic training, 36 probationer constables with an average of 20 months' police experience, and 30 control subjects matched with the police groups in socioeconomic status. All subjects also gave open-ended responses to questions on controversial issues. Compared with control subjects, the recruits' and probationers' scores were significantly more conservative and authoritarian, and the probationers' open-ended responses on the death penalty and coloured immigration were rated significantly more illiberal/intolerant. The probationers' responses on coloured immigration were also rated significantly more illiberal/intolerant than those of the recruits. Among the recruits, basic training was followed by a reduction in conservatism and authoritarianism. The findings suggest that the police force attracts conservative and authoritarian personalities, that basic training has a temporarily liberalizing effect, and that continued police service results in increasingly illiberal/intolerant attitudes towards coloured immigration.
Synthesis and Characterization of Highly Luminescent CdSe—Core CdS/Zn<sub>0.5</sub>Cd<sub>0.5</sub>S/ZnS Multishell Nanocrystals. (2005)

Abstract For Abstract see ChemInform Abstract in Full Text.
Exogenous ochronosis and pigmented colloid milium from hydroquinone bleaching creams (1975)

An outbreak of ochronosis and colloid milium is described after the use of strong hydroquinone bleaching creams. These phenomena developed only after a few years, and took place when the melanocytes had overcome the bleaching influence. Sun-exposure and thorough inunction of the cream were required for the more advanced changes. Analogous changes have been seen when the skin is exposed to certain crude fuels in individuals working in the sun, and phenolic components in the fuels are suspected. The study presented here covers the clinical, histological, histochemical, electron microscopical and pathogenetic features as seen in thirty-five cases of hydroquinone damage to the dermis in South Africa.
High-speed InGaAsP constricted-mesa lasers (1986)

Recently, the bandwidths of semiconductor lasers, detectors, and optical transmission systems have been dramatically increased. The considerations used to achieve a record 26.5 GHz bandwidth in a 1.3 μm InGaAsP laser at -60°C are described here. The small-signal modulation characteristics of a number of different laser structures are compared. Several large-signal modulation experiments are described with emphasis on the laser response to 8 Gbit/s modulation.
Metagenomic abundance estimation and diagnostic testing on species level (2012)

One goal of sequencing-based metagenomic community analysis is the quantitative taxonomic assessment of microbial community compositions. In particular, relative quantification of taxons is of high relevance for metagenomic diagnostics or microbial community comparison. However, the majority of existing approaches quantify at low resolution (e.g. at phylum level), rely on the existence of special genes (e.g. 16S), or have severe problems discerning species with highly similar genome sequences. Yet, problems as metagenomic diagnostics require accurate quantification on species level. We developed Genome Abundance Similarity Correction (GASiC), a method to estimate true genome abundances via read alignment by considering reference genome similarities in a non-negative LASSO approach. We demonstrate GASiC's superior performance over existing methods on simulated benchmark data as well as on real data. In addition, we present applications to datasets of both bacterial DNA and viral RNA source. We further discuss our approach as an alternative to PCR-based DNA quantification.
A Pilot <i>Ex</i> <i>Vivo</i> Evaluation of a Telerobotic System for Transurethral Intervention and Surveillance (2014)

The dexterous robot allowed for visualization as well as provided adequate ablation and en bloc resection of bladder lesions throughout the entire bladder.
Estrogen Regulation of Cyclin E2 Requires Cyclin D1 but Not c-Myc (2009)

During estrogen-induced proliferation, c-Myc and cyclin D1 initiate independent pathways that activate cyclin E1-Cdk2 by sequestration and/or downregulation of the CDK inhibitor p21(Waf1/Cip1), without significant increases in cyclin E1 protein levels. In contrast, cyclin E2 undergoes a marked increase in expression, which occurs within 9 to 12 h of estrogen treatment of antiestrogen-pretreated MCF-7 breast cancer cells. Both E cyclins are important to estrogen action, as small interfering RNA (siRNA)-mediated knockdown of either cyclin E1 or cyclin E2 attenuated estrogen-mediated proliferation. Inducible expression of cyclin D1 upregulated cyclin E2, while siRNA-mediated knockdown of cyclin D1 attenuated estrogen effects on cyclin E2. However, manipulation of c-Myc levels did not profoundly affect cyclin E2. Cyclin E2 induction by estrogen was accompanied by recruitment of E2F1 to the cyclin E1 and E2 promoters, and cyclin D1 induction was sufficient for E2F1 recruitment. siRNA-mediated knockdown of the chromatin remodelling factor CHD8 prevented cyclin E2 upregulation. Together, these data indicate that cyclin E2-Cdk2 activation by estrogen occurs via E2F- and CHD8-mediated transcription of cyclin E2 downstream of cyclin D1. This contrasts with the predominant regulation of cyclin E1-Cdk2 activity via CDK inhibitor association downstream of both c-Myc and cyclin D1 and indicates that cyclins E1 and E2 are not always coordinately regulated.
Regularization of Body Core Temperature Prediction during Physical Activity (2006)

This paper deals with the prediction of body core temperature during physical activity in different environmental conditions using first-principles models and data-driven models. We argue that prediction of physiological variables through other correlated physiological variables using data-driven techniques is an ill-posed problem. To make predictions produced by data-driven models accurate and stable they need to be regularized. We demonstrate on data collected during laboratory study that data-driven models, if regularized properly, can outperform first-principles models in terms of accuracy of core temperature predictions. We also show that data-driven models can be made "portable" from one subject to another, thus, making them a valuable, practical tool when data from only one subject is available to "train" the model.
Renal IL-17 expression in human ANCA-associated glomerulonephritis (2012)

Interleukin-17A (IL-17) promotes inflammatory renal tissue damage in mouse models of crescentic glomerulonephritis, including murine experimental autoimmune anti-myeloperoxidase glomerulonephritis, which most likely depends on IL-17-producing Th17 cells. In human anti-neutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis, however, the cellular sources of IL-17 remain to be elucidated. Therefore, we analyzed human kidney biopsies of active necrotizing and crescentic ANCA-associated glomerulonephritis by immunohistochemistry using an IL-17-specific antibody and by immunofluorescent colocalization with cell type markers. We detected numerous IL-17-expressing (IL-17(+)) cells in the glomeruli and in the tubulointerstitium. Unexpectedly, most of these IL-17(+) cells were polymorphonuclear neutrophilic granulocytes, while IL-17(+) T cells and IL-17(+) mast cells were present at significantly lower frequencies. IL-17 was not detected in other infiltrating or resident kidney cells. In those patients who had not received immunosuppressive treatment before biopsy, serum creatinine levels were positively correlated with tubulointerstitial IL-17(+) neutrophils as well as IL-17(+) T cells. Furthermore, we could demonstrate that purified human blood neutrophils expressed IL-17 protein and released it upon stimulation in vitro. In conclusion, these results support a pathogenic role for IL-17 in human ANCA-associated glomerulonephritis. Our data suggest that in the acute stage of the disease neutrophils may act as an important immediate-early innate source of IL-17 and may thereby initiate and promote ongoing renal inflammation. IL-17 may thus be a target for treating acute ANCA-associated glomerulonephritis.
Urinary Bladder Involvement in Patients with Systemic lupus Erythematosus With Review of the Literature (2000)

Diverse etiologies may cause lower urinary tract symptoms in patients with SLE. Lupus cystitis is strongly associated with gastrointestinal involvement and abdominal CT can be a useful radiologic tool to investigate the gastrointestinal tract involvement in patients with lupus cystitis.
Analysis of Multiloop Control Strategies for LC/CL/LCL-Filtered Voltage-Source and Current-Source Inverters (2005)

Multiloop control strategies have commonly been used to control power inverters of both the voltage-source and current-source topologies for power conversion applications including uninterruptible power supplies and utility interfaces for distributed power generation. However, these control strategies tend to be developed and comparatively evaluated for a particular application, with strategies for other applications presented as independent new developments. This paper presents a generalized analysis of different multiloop control approaches using alternative feedback control variables for several popularly adopted system configurations, highlighting similarities and identifying a generalized optimal control-variable selection criterion that is applicable across most multiloop-controlled inverter systems. The generality of the presented optimal variable selection criterion has been verified through the close similarities between the time-domain waveforms of the different inverter systems simulated in MATLAB Simulink and implemented experimentally in the laboratory.
Fatty acid amide hydrolase inhibitors confer anti-invasive and antimetastatic effects on lung cancer cells (2016)

Inhibition of endocannabinoid degradation has been suggested as tool for activation of endogenous tumor defense. One of these strategies lies in blockade of fatty acid amide hydrolase (FAAH) which catalyzes the degradation of endocannabinoids (anandamide [AEA], 2-arachidonoylglycerol [2-AG]) and endocannabinoid-like substances (N-oleoylethanolamine [OEA], N-palmitoylethanolamine [PEA]). This study addressed the impact of two FAAH inhibitors (arachidonoyl serotonin [AA-5HT], URB597) on A549 lung cancer cell metastasis and invasion. LC-MS analyses revealed increased levels of FAAH substrates (AEA, 2-AG, OEA, PEA) in cells incubated with either FAAH inhibitor. In athymic nude mice FAAH inhibitors were shown to elicit a dose-dependent antimetastatic action yielding a 67% and 62% inhibition of metastatic lung nodules following repeated administration of 15 mg/kg AA-5HT and 5 mg/kg URB597, respectively. In vitro, a concentration-dependent anti-invasive action of either FAAH inhibitor was demonstrated, accompanied with upregulation of tissue inhibitor of matrix metalloproteinases-1 (TIMP-1). Using siRNA approaches, a causal link between the TIMP-1-upregulating and anti-invasive action of FAAH inhibitors was confirmed. Moreover, knockdown of FAAH by siRNA was shown to confer decreased cancer cell invasiveness and increased TIMP-1 expression. Inhibitor experiments point toward a role of CB2 and transient receptor potential vanilloid 1 in conferring anti-invasive effects of FAAH inhibitors and FAAH siRNA. Finally, antimetastatic and anti-invasive effects were confirmed for all FAAH substrates with AEA and OEA causing a TIMP-1-dependent anti-invasive action. Collectively, the present study provides first-time proof for an antimetastatic action of FAAH inhibitors. As mechanism of its anti-invasive properties an upregulation of TIMP-1 was identified.
Modification of proinflammatory cytokine production by the antirheumatic agents tenidap and naproxen. A possible correlate with clinical acute phase response (1992)

The cytokines IL-6, IL-1, and TNF play a key role in the pathogenesis of rheumatoid arthritis (RA) and initiate hepatic serum amyloid A (SAA) expression after injury. To provide a possible mechanistic explanation for the previous observation that plasma SAA concentrations decreased during treatment of RA patients with tenidap, but increased during treatment with naproxen, the present study compared the effects of tenidap and naproxen on the two stages of SAA expression: cytokine production by human PBMC and cytokine-stimulated SAA synthesis by human Hep3B hepatoma cells. Tenidap inhibited production of IL-6 greater than TNF greater than IL-1; the effect of naproxen on production of all three cytokines was lesser and least on IL-6. Indeed, an increase in IL-6 production was observed after exposure to naproxen. PBMC beta-2-microglobulin production and total protein synthesis were unaffected at concentrations and times at which effects on cytokine production were observed. Cell density was a significant factor in the extent to which cytokines were stimulated by LPS. Approximately physiologic cell densities, 0.5 to 1 x 10(6) cells/ml, were optimal for stimulation of IL-1-beta and IL-6 production by LPS; however, greater amounts of TNF were produced at lower cell densities. Because neither tenidap nor naproxen inhibited SAA synthesis by cytokine-stimulated Hep3B cells and because they differ most significantly in their effect on IL-6 production, the results support a role for IL-6 in the continued stimulation of SAA production during RA.
Rate adaptive indoor infrared wireless communication systems using repeated and punctured convolutional codes (2003)

We propose a rate adaptive transmission scheme using repeated and punctured convolutional codes for indoor infrared wireless communications. The proposed system uses a coding scheme consisting of an outer punctured convolutional code and an inner repetition code of length RR used for each punctured convolutional code symbol, and varies the code rate of the punctured convolutional codes and the rate reduction factor of the repetition codes, that is, the bit rate varies adaptively depending on the channel conditions. We analyze the performance and show that the proposed system can realize communications in worse channel conditions at the expense of the bit rate, while maximizing the throughput available to a user on his position.
Expression of human SOX18 in normal tissues and tumors (2002)

SOX proteins are a family of transcription factors with high-mobility-group DNA-binding domain (HMG box) homologous to SRY, which play key roles in embryogenesis. Xenopus Sox17α, Sox17β, Sox3 and mouse Sox7 are reported to be negative regulators of the WNT-β-catenin-TCF signaling pathway. SOX7, SOX17, and SOX18 constitute a subfamily among the SOX gene family. Here, expression of SOX18 mRNA was investigated using Northern blot analysis, RNA dot blot analysis, and cDNA-PCR. SOX18 mRNA was significantly highly expressed in ventricles and inter-ventricular septum of adult heart among various normal human tissues. SOX18 mRNA was relatively highly expressed in stomach and jejunum in the gastrointestinal tract. SOX18 mRNA was relatively highly expressed in TMK1 and MKN45 among 7 gastric cancer cell lines. SOX18 mRNA was expressed in all out of 7 pancreatic cancer cell lines, and was relatively highly expressed in PANC-1, Hs700T, Hs766T and MIA PaCa-2. Expression level of SOX18 mRNA in MCF-7 cells (breast cancer) was not affected by β-estradiol. SOX18 mRNA was expressed in all out of 5 embryonal tumor cell lines, and was relatively highly expressed in NT2 with the potential to differentiate into neuronal cells. Expression level of SOX18 mRNA in NT2 cells was down-regulated by all-trans retinoic acid. This is the first report on comprehensive expression analyses of SOX18 mRNA in normal human tissues and tumors.
Study of sol–gel processing for fabrication of hollow silica–aerogel spheres (1990)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation K. Y. Jang, K. Kim, R. S. Upadhye; Study of sol–gel processing for fabrication of hollow silica–aerogel spheres. J. Vac. Sci. Technol. A 1 May 1990; 8 (3): 1732–1735. https://doi.org/10.1116/1.576839 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAVS: Science & Technology of Materials Interfaces and ProcessingJournal of Vacuum Science & Technology A Search Advanced Search |Citation Search
Investigation of bone formation using calcium phosphate glass cement in beagle dogs (2010)

Purpose: Among available biomaterials, bioceramics have drawn special interest due to their bioactivity and the possibility of tailoring their composition. The degradation rate and formulation of bioceramics can be altered to mimic the compositions of the mineral phase of bone. The aim of this study was to investigate the bone formation effect of amorphous calcium phos phate glass cement (CPGC) synthesized by a melting and quenching process. Methods: In five male beagle dogs, 4 × 4 mm 1-wall intrabony defects were created bilaterally at the mesial or distal aspect of the mandibular second and fourth premolars. Each of the four defects was divided according to graft materials: CPGC with collagen membrane (CM), biphasic calcium phosphate (BCP) with CM, CM alone, or a surgical flap operation only. The dogs were sacrificed 8 weeks post-surgery, and block sections of the defects were collected for histologic and histometric analysis. Results: There were significant differences in bone formation and cementum regeneration between the experimental and control groups. In particular, the CPGC and BCP groups showed greater bone formation than the CM and control groups. Conclusions: In conclusion, CPGC was replaced rapidly with an abundant volume of new bone; CPGC also contributed slightly to regeneration of the periodontal apparatus.