gebhart/patrepeval huggingface dataset:
Performance analysis of a shipborne gyrocompass with a multi-antenna GPS system (2002)

A four-receiver configuration was used to estimate the three attitude parameters and assess the headings obtained with a Sperry Mark 3 Model C gyrocompass mounted on a 1500 tonnes, 72-m vessel. The GPS configuration consisted of four 10-channel NovAtel GPSCards operating in independent mode. The antenna separations varied between 5 and 15 m. The antenna locations in the ship coordinate system were obtained through a combination of a conventional and GPS survey. The remaining misalignment between the gyrocompass and the multi-receiver configuration was estimated by comparing GPS and gyrocompass heading measurements made throughout the sea trial. The formulation used to estimate the above attitude parameters is described. The multi-receiver data was processed with The University of Calgary's MULTINAV attitude software. The performance of the gyrocompass was assessed using 10 hours of data collected over a two-day period in Spring 1993 under a wide range of ship manoeuvres such as acceleration, deceleration and 360/spl deg/ turns. The estimated double difference carrier phase residuals, which provide a measure of receiver carrier phase noise and multipath, were below the 5 mm level. The estimated accuracy of the GPS-derived heading parameter was 2.2 arcmins or 0.04/spl deg/ and the standard deviation of the differences between GPS and gyrocompass headings during straight trajectory segments was 0.16/spl deg/. The use of a two-receiver configuration to determine the heading component was shown to deliver a level of accuracy similar to that obtained with the four-receiver configuration.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Basal ganglia-thalamocortical circuits: parallel substrates for motor, oculomotor, "prefrontal" and "limbic" functions. (1990)

The central theme of the "segregated circuits" hypothesis is that structural convergence and functional integration occurs within, rather than between, each of the identified circuits. Admittedly, the anatomical evidence upon which this scheme is based remains incomplete. The hypothesis continues to be predicated largely on comparisons of anterograde and retrograde labeling studies carried out in different sets of animals. Only in the case of the "motor" circuit has evidence for the continuity of the loop been demonstrated directly in individual subjects; for the other circuits, such continuity is inferred from comparisons of data on different components of each circuit obtained in separate experiments. Because of the marked compression of pathways leading from cortex through basal ganglia to thalamus, comparisons of projection topography across experimental subjects may be hazardous. Definitive tests of the hypothesis of maintained segregation await additional double- and multiple-label tract-tracing experiments wherein the continuity of one circuit, or the segregation of adjacent circuits, can be examined directly in individual subjects. It is worthy of note, however, that the few studies to date that have employed this methodology have generated results consistent with the segregated circuits hypothesis. Moreover, single cell recordings in behaving animals have shown striking preservation of functional specificity at the level of individual neurons throughout the "motor" and "oculomotor" circuits. It is difficult to imagine how such functional specificity could be maintained in the absence of strict topographic specificity within the sequential projections that comprise these two circuits. This is not to say, however, that we expect the internal structure of functional channels (e.g., the "arm" channel within the "motor" circuit) to have cable-like, point-to-point topography. When the grain of analysis is sufficiently fine, anatomical studies have shown repeatedly that the terminal fields of internuclear projections (e.g., to striatum, pallidum, nigra, thalamus, etc.) often appear patchy and highly divergent, suggesting that neighboring groups of projection cells tend to influence interdigitating clusters of postsynaptic neurons. While more intricate and complex than simple point-to-point topography, however, this type arrangement should also be capable of maintaining functional specificity. As discussed briefly above, it is not yet clear to what extent the inputs to the "motor" circuit from the different precentral motor fields (e.g., MC, SMA, APA) are integrated in their passage through the circuit. It now appears that at the level of the putamen such inputs remain segregated.(ABSTRACT TRUNCATED AT 400 WORDS)
A novel predistorter for power amplifier (2003)

In this paper, we propose a novel predistortion scheme with the aid of a piecewise polynomial modeling of the AM/AM and AM/PM characteristics for an high power amplifier (HPA). Multiple polynomials are used to predistort the input signal instead of a single one, by dividing the input signal range into several regions. For a HPA model we considered, we optimized the number of regions, subdivision points and order of polynomial functions in each region to increase the predistortion performance without an increase of computational load. From the simulation results investigated in this paper, the proposed method showed about a 0.5 dB gain in total degradation compared to a conventional polynomial predistortion method.
Role of nitric oxide and protein kinase C in ACh-induced cardioprotection (2001)

We examined the roles of nitric oxide and protein kinase C (PKC) in ACh-produced protection of cultured cardiomyocytes during simulated ischemia and reoxygenation. Cell viability was quantified using propidium iodide in chick embryonic ventricular myocytes. O(2) radicals were quantified using 2',7'-dichlorofluorescin diacetate. After a 10-min infusion of ACh (0.5 or 1 mM) and a 10-min drug-free period, we simulated ischemia for 1 h and reoxygenation for 3 h. ACh reduced cardiocyte death [32 +/- 4%; n = 6 and 23 +/- 4%; n = 7 (P < 0.05)] and attenuated oxidant stress during ischemia and reoxygenation in a concentration-dependent manner compared with controls (47 +/- 4%; n = 8; P < 0.05). The increase in O(2) radicals before simulated ischemia [357 +/- 49; n = 4 and 528 +/- 52; n = 8 vs. 211 +/- 34; n = 8; P < 0.05 (arbitrary units)] was abolished by the specific nitric oxide synthase inhibitor N(G)-nitro-L-arginine methyl ester (L-NAME) and was markedly attenuated by N(G)-monomethyl-L-arginine (L-NMMA). L-NAME or L-NMMA blocked the protective effects of ACh, which selectively increased PKC-epsilon isoform activity in the particulate fraction. The PKC inhibitor Gö-6976 had no effect on O(2) radical production before simulated ischemia but it abolished the protection; therefore nitric oxide is a large component of ACh-generated O(2) radicals. Nitric oxide and O(2) radicals activate the PKC-epsilon isoform by which ACh protects against injury.
Cotton (&lt;i&gt;Gossypium hirsutum&lt;/i&gt; L.) (2006)

Considering the economic importance of cotton in many developing and developed countries, there is an urgent need to accelerate the application of biotechnological tools to address the problems associated with the production of this crop and to improve the quality of fiber and seed. This requires a simple yet robust gene delivery/transformant recovery system. A protocol for the production of transgenic cotton plants was refined in our laboratory. It involves Agrobacterium-mediated transformation of cotton cells, selection of stable transgenic callus lines, and recovery of plants via somatic embryogenesis. A detailed description of the protocol is provided in this chapter.
A subcutaneously injected UV-inactivated SARS coronavirus vaccine elicits systemic humoral immunity in mice (2004)

The recent emergence of severe acute respiratory syndrome (SARS) was caused by a novel coronavirus, SARS-CoV. It spread rapidly to many countries and developing a SARS vaccine is now urgently required. In order to study the immunogenicity of UV-inactivated purified SARS-CoV virion as a vaccine candidate, we subcutaneously immunized mice with UV-inactivated SARS-CoV with or without an adjuvant. We chose aluminum hydroxide gel (alum) as an adjuvant, because of its long safety history for human use. We observed that the UV-inactivated SARS-CoV virion elicited a high level of humoral immunity, resulting in the generation of long-term antibody secreting and memory B cells. With the addition of alum to the vaccine formula, serum IgG production was augmented and reached a level similar to that found in hyper-immunized mice, though it was still insufficient to elicit serum IgA antibodies. Notably, the SARS-CoV virion itself was able to induce long-term antibody production even without an adjuvant. Anti-SARS-CoV antibodies elicited in mice recognized both the spike and nucleocapsid proteins of the virus and were able to neutralize the virus. Furthermore, the UV-inactivated virion induced regional lymph node T-cell proliferation and significant levels of cytokine production (IL-2, IL-4, IL-5, IFN-gamma and TNF-alpha) upon restimulation with inactivated SARS-CoV virion in vitro. Thus, a whole killed virion could serve as a candidate antigen for a SARS vaccine to elicit both humoral and cellular immunity.
Dinucleotide repeat polymorphisms at the D11S439 and HBB loci (1992)

Journal Article Dinucleotide repeat polymorphisms at the D11S439 and HBB loci Get access X. Y. Hauge, X. Y. Hauge Departments of Biochemistry and Medical Genetics, Oregon Health Sciences UniversityPortland, OR 97201, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar R. Litt, R. Litt Departments of Biochemistry and Medical Genetics, Oregon Health Sciences UniversityPortland, OR 97201, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar M. Litt M. Litt * Departments of Biochemistry and Medical Genetics, Oregon Health Sciences UniversityPortland, OR 97201, USA *To whom correspondence should be addressed Search for other works by this author on: Oxford Academic PubMed Google Scholar Human Molecular Genetics, Volume 1, Issue 7, October 1992, Page 548, https://doi.org/10.1093/hmg/1.7.548 Published: 01 October 1992
Toward adaptive radiotherapy for head and neck patients: Feasibility study on using CT‐to‐CBCT deformable registration for “dose of the day” calculations (2014)

Deforming a planning CT to match a daily CBCT provides the tools needed for the calculation of the "dose of the day" without the need to acquire a new CT. The initial clinical application of our method will be weekly offline calculations of the "dose of the day," and use this information to inform adaptive radiotherapy (ART). The work here presented is a first step into a full implementation of a "dose-driven" online ART.
Peak Experiences with Electronic Dance Music (2019)

This paper investigates the role of musical features in shaping peak-pleasurable experiences of electronic dance music (EDM). Typically, large structural and dynamic changes occur in an EDM track, which can be referred to as the break routine, consisting of breakdown, build-up, and drop. Twenty-four participants listened to four EDM excerpts featuring break routines, and one excerpt without a break routine. Measures were taken of skin conductance, self-reported affect, and embodied aspects of subjective experience, and incidence of pleasant bodily sensations. Participants reported intense affective experience with EDM despite being removed from the club context, and attributed this experience to the drop in particular. They described these experiences as energizing and uplifting, and pointed to an embodied, kinaesthetic experience of the music. Drop sections of the music were associated with significantly higher skin conductance response than other sections of the break routine. Analysis confirms correlation between specific acoustic and musical features and peak-response as observed with other music genres, and also identifies novel musical characteristics particular to EDM associated with peak experience. This shows that pleasurable peak experience with EDM is related to specific musical features, and has embodied spatial and kinaesthetic experiential qualities even when listened to without dancing and away from the club context.
Ocular allergy: recognizing and diagnosing hypersensitivity disorders of the ocular surface (2012)

Ocular allergy includes several clinically different conditions that can be considered as hypersensitivity disorders of the ocular surface. The classification of these conditions is complex, and their epidemiology has not been adequately studied because of the lack of unequivocal nomenclature. Ocular allergy symptoms are often, but not always, associated with other allergic manifestations, mostly rhinitis. However, specific ocular allergic diseases need to be recognized and managed by a team that includes both an ophthalmologist and an allergist. The diagnosis of ocular allergy is usually based on clinical history and signs and symptoms, with the support of in vivo and in vitro tests when the identification of the specific allergic sensitization is required for patient management. The aims of this Task Force Report are (i) to unify the nomenclature and classification of ocular allergy, by combining the ophthalmology and allergy Allergic Rhinitis and its Impact on Asthma criteria; (ii) to describe current methods of diagnosis; (iii) to summarize the therapeutic options for the management of ocular allergic inflammation.
Does facial sebum excretion really affect the development of acne? (2005)

Increased levels of facial sebum secretion were observed in patients with acne. Our findings indicate that increased sebum levels do not directly cause development of acne lesions.
Studies on the Interaction between Collagen and a Plasma Kallikrein-Like Activity EVIDENCE FOR A SURFACE-ACTIVE ENZYME SYSTEM (1972)

This study has demonstrated that collagen particles, after exposure to platelet-poor human plasma and subsequent washing, generate a kinin-like agent when incubated with prekinin substrate. The binding of kinin-generating activity to collagen in the plasma collagen incubation mixture occurs rapidly, whereas the loss of this activity in the incubation mixture occurs relatively slowly. The Hageman factor appeared to be necessary for the surface-bound kinin-generating activity, as this activity was absent in collagen exposed to Hageman factor-deficient plasma. These studies have partially characterized the plasma-derived enzymatic activity bound to collagen. Incubation of collagen with plasma caused a concentration-dependent reduction in the kinin-producing activity which was generated by the addition of ellagic acid, a known activator of plasma kallikrein. The kinin-inducing activity bound to collagen is inhibited by soybean trypsin inhibitor, Trasylol, serum C1 inactivator and the plasma alpha(2)-macroglobulin, but not by lima bean trypsin inhibitor. An eluate prepared from plasma-treated collagen, when compared with purified plasma kallikrein, shared a similar inhibitor profile. Selective chemical blockage of the free carboxyl groups on the collagen molecule, or heat denaturation, inactivated the ability of the collagen to generate kinin-like activity after incubation with plasma. Removal of the collagen telopeptides or blockage of the free amino groups failed to affect the collagen-plasma interaction. The binding of partially purified plasma kallikrein to collagen was found to have similar structural and chemical requirements. These data indicate that there is a structural and chemical specificity for the activation and binding of plasma kallikrein-like activity by collagen. These studies suggest that a plasma kallikrein may function as a surface-bound enzyme system.
Eficácia da utilização de grânulos de argila como veículo para a aplicação aérea de sulfentrazone e isoxaflutole em área de implantação de eucalipto (2010)

Realizou-se um experimento em uma área de implantação da cultura do eucalipto no município de São Miguel Arcanjo-SP, com o objetivo de avaliar a eficácia da aplicação aérea de grânulos de argila como veículo dos herbicidas sulfentrazone e isoxaflutole, no controle de plantas daninhas. Foi realizada aplicação aérea dos herbicidas sulfentrazone, nas doses de 500 e 750 g i.a. ha-1, e isoxaflutole, nas doses de 150 e 225 g i.a. ha-1, utilizando-se como veículo grânulos de argila com densidade de 1,05 g cm ³, alta capacidade de absorção (24 mL 100 g-1), alta resistência ao desgaste e tamanho das partículas entre 500 mícrons e 1 mm. Também foram feitas aplicações via líquida dos mesmos herbicidas e doses com um pulverizador convencional, acoplado a um trator. Além desses tratamentos, foi mantida uma parcela testemunha, sem aplicação dos herbicidas. Nas parcelas experimentais foram semeadas as espécies de plantas daninhas Brachiaria decumbens, Ipomoea grandifolia, Merremia cissoides e Panicum maximum, sendo realizadas avaliações visuais de controle aos 75 e 110 dias após a aplicação. Em geral, foram observados, nas plantas daninhas avaliadas, resultados de controle semelhantes ou superiores para a aplicação aérea (via grânulos) até 75 DAA e superiores para essa modalidade de aplicação aos 110 DAA, indicando uma extensão no período do efeito do residual dos herbicidas estudados.
Genetic transformation: a tool to study protein targeting in diatoms. (2007)

Diatoms are unicellular photoautotrophic eukaryotes that play an important role in ecology by fixing large amounts of CO2 in the oceans. Because they evolved by secondary endocytobiosis-- a process of uptake of a eukaryotic alga into another eukaryotic cell--they have a rather unusual cell biology and genetic constitution. Because the preparation of organelles is rather difficult as a result of the cytosolic structures, genetic transformation and expression of preproteins fused to green fluorescent protein (GFP) became one of the major tools to analyze subcellular localization of proteins in diatoms. Meanwhile several groups successfully attempted to develop genetic transformation protocols for diatoms. These methods are based on "biolistic" DNA delivery via a particle gun and allow the introduction and expression of foreign genes in the algae. Here a protocol for the genetic transformation of the diatom Phaeodactylum tricornutum is described as well as the subsequent characterization of the transformants.
Comparisons of volatile organic chemical content of news, sheetfed, and heatset ink formulations (2001)

Abstract Volatile organic compound (VOC) contents of news, sheetfed, and heatset inks were evaluated by using different methods, and comparison of data with significant differences is reported. Environmental Protection Agency (EPA) Method 24, EPA Method 24A, and Bay Area Method 30 were the methods used. Ingredients of news inks were tested with Method 24, and experimental and calculated percentage VOC values of formulated inks were compared. Along with United States Department of Agriculture's 100% vegetable oil‐based inks, commercial vegetable oil‐based, and petroleum‐based inks were used for comparison. Significant differences between methods, colors, and sources are discussed.
Carcinogenicity of Epoxides, Lactones, and Peroxy Compounds. IV. Tumor Response in Epithelial and Connective Tissue in Mice and Rats&lt;xref ref-type="fn" rid="FN2"&gt;2&lt;/xref&gt; (1966)

The carcinogenic potencies of a series of alkylating and peroxy compounds were compared by the use of various routes of administration in mice and rats. Twelve of these compounds, earlier tested on mouse skin, were tested by one or more of the following routes: subcutaneous injection in mice and rats and intragastric feeding in rats. These experiments showed that those compounds tumorigenic to mouse skin are also active by other routes. These compounds are: β-propiolactone, β-butyrolactone, &lt;it&gt;d,l&lt;/it&gt;-diepoxybutane, glycidaldehyde, and 1,2,5,6-diepoxyhexane. Those compounds inactive on mouse skin are weakly active or inactive by other routes. These compounds are: cumene hydroperoxide, 9,10-epoxy-stearic acid, diketene, 2,2,4-trimethylhydroxypentenoic acid-β-lactone, cyclohexenehydroperoxide, and lauroyl peroxide. β-Propiolactone and β-butyrolactone are mouse-skin carcinogens and induce gastric cancers when fed repeatedly to rats; however, 3 epoxides carcinogenic to mouse skin (glycidaldehyde, &lt;it&gt;d,l&lt;/it&gt;-diepoxybutane, and 1-ethyleneoxy-3,4-epoxy cyclohexane) do not induce gastric cancers in rats. This finding is related to the rapid acid-catalyzed hydrolysis of epoxides in the rat stomach. The compounds tested induced tumors mainly at the site of application and did not give any significant incidence of tumors at sites distant from the site of application. These experiments indicate that connective tissue of rats is not unusually sensitive to tumor induction by these compounds and that subcutaneous injection in the rat is a useful system for the evaluation of potential carcinogens.
In Vivo and Ex Vivo Evaluation of the Antithrombogenicity of Human Thrombomodulin Immobilized Biomaterials (1995)

Human thrombomodulin (hTM) is a newly described endothelial cell associated protein that functions as a potent natural anticoagulant by converting thrombin from a procoagulant protease to an anticoagulant. Focusing on the establishment of the practical evaluation of hTM immobilized materials, the activity of immobilized hTM was evaluated by in vivo and ex vivo blood contacting tests. As the basis for immobilization, regenerated cellulose films and hollow fibers were used. For the in vivo test, hTM immobilized cellular hollow fibers were implanted into dog blood vessels. Using hTM immobilized cellulose hollow fibers, a small scale dialyzer was assembled and its antithrombogenic activity was studied using human blood. As a result, it was revealed that the immobilized hTM still has co-enzymatic activity for activation of Protein C and anticoagulant activity. The coagulation time of the human blood passed through the hTM immobilized small dialyzer was effectively prolonged. It is expected that hTM immobilized cellulose should be a useful antithrombogenic biomaterial.
Rate-one Space Frequency Block Codes with Maximum Diversity Gain for MIMO-OFDM (2004)

A novel rate-1, space-frequency (SF) code for an orthogonal frequency division multiplexing (OFDM) system with transmit (M) and receive (N) antennas that achieves the maximum diversity attainable over frequency-selective channels is proposed. Since the SF code symbol is transmitted in one OFDM block duration, it has smaller processing delay than previously proposed space-time-frequency (STF) block codes.
Propulsion of Ripples on Glass by Ion Bombardment (2006)

The propulsion of surface ripples on SiO(2) by an ion beam was investigated by in situ electron microscopy. The observed propagation of the ripples contradicts existing models for ion-beam-induced ripple development. A new model based on the Navier-Stokes relations for viscous flow in a thin layer is introduced. It includes inhomogeneous viscous flow, driven by spatial variations in the deposition of the energy of the ion beam. The model explains the observed reversed propagation. The hitherto unknown propulsion mechanism is important for understanding nanoscale pattern formation by ion bombardment.