gebhart/patrepeval huggingface dataset:
Chaining Planar Homographies for Fast and Reliable 3D Plane Tracking (2006)

This paper addresses the problem of tracking a 3D plane over a sequence of images acquired by a free moving camera, a task that is of central importance to a wide variety of vision tasks. A feature-based method is proposed which given a triplet of consecutive images and a plane homography between the first two of them, estimates the homography induced by the same plane between the second and third images, without requiring the plane to be segmented from the rest of the scene. Thus, the proposed method operates by "chaining" (i.e. propagating) across frames the image-to-image homographies due to some 3D plane. The chaining operation represents projective space using a "plane + parallax" decomposition, which permits the combination of constraints arising from all available point matches, regardless of whether they actually lie on the tracked 3D plane or not. Experimental results are also provided
Topical Cyclosporin A in the Management of Postkeratoplasty Glaucoma (1997)

Topical cyclosporin A 0.5% may be substituted for topical corticosteroids to aid in the management of postkeratoplasty patients with glaucoma. However, the resultant decrease in IOP may be associated with an increased risk for immune rejections.
The Polymerase Chain Reaction (Nobel Lecture) (1994)

What did it feel like to invent the polymerase chain reaction? In his Nobel Lecture K. B. Mullis gives an entertaining and philosophical account of his journey that resulted in a powerful new method, completely automated in the meantime, for the synthesis of as much identical DNA as desired from one single strand.
A Trust Company - Switzerland or Offshore? (1996)

A Trust Company - Switzerland or Offshore? Get access S. Durr Gerber S. Durr Gerber Bank Julius Baer & Co. Ltd.Bahnhofstrasse 36, 8001 Zurich, Postfach CH-8010, Switzerland, Telephone: (01) 228 51 11, Facsimile: (01) 211 25 60 Search for other works by this author on: Oxford Academic Google Scholar Trusts & Trustees, Volume 2, Issue 5, April 1996, Pages 37–39, https://doi.org/10.1093/tandt/2.5.37 Published: 01 April 1996
SimpleConcepts: Support for constraints on generic types in C++ (2013)

Abstract—Generic programming plays an essential role in C++ software through the use of templates. However, both the creation and use of template libraries is hindered by the fact that the language does not allow programmers to specify constraints on generic types. To date, no proposal to update the language to provide concepts has survived the committee process. Until that time comes, as a form of early support, this paper introduces SimpleConcepts, an extension to C++11 that provides support for concepts, sets of constraints on generic types. SimpleConcepts features are parsed according to an island grammar and source-to-source translation is used to lower concepts to pure C++11 code.
청소년 알레르기성 질환의 복합성과 중증도가 자살 생각에 미치는 영향 (2016)

Background & Objectives: There were increasing evidence about the relationship between allergy related disease such as asthma, atopic dermatitis and allergic rhinitis and suicide ideation. However little was known about the concrete relatedness between severity and comorbidity of allergy related disease with suicide ideation. The objective of this study was to investigate the cases of the prevalence of suicide ideation among adolescents with allergy related disease such as asthma, atopic dermatitis and allergic rhinitis, and examine the association between allergy related disease and suicidal ideation among adolescents in South Korea. Methods: Data was based on Korean Youth Risk Behavior Web-based Survey(2014) which was a cross-sectional study containing 34,874 Korean middle and high school students who diagnosed with allergy related disease. We used the weights, strata and primary sampling unit information provided by the public use dataset to compute descriptive statistics and logistic regressions. Computations were done with SPSS version 20.0. Results: 19.9%, 15.6%, 13.8% of adolescents who suffered from one, two and three of allergy related diseases respectively reported having been thought of suicide ideation. Socio-demographic factors were adjusted as control variables. Students with greater severity of disease were more likely to have suicide ideation. Odds ratio for students who were absent one to three days from school because of allergies was 1.96(95% CI 1.51-2.46), and odds ratio for those who were absent more than four days from school was 3.60 (95% CI 2.46-5.28). Conclusions: Given that adolescents’ severity and comorbidity of allergy related disease were clearly associated with suicide ideation, suicide prevention programs for adolescents with allergy related disease should be improved by strategic approaches towards the severity and comorbidity of disease.
Involvement of SH2-containing Phosphotyrosine Phosphatase Syp in Erythropoietin Receptor Signal Transduction Pathways (1995)

Erythropoietin (Epo) regulates the proliferation and differentiation of erythroid precursors. The phosphorylation of proteins at tyrosine residues is critical in the growth signaling induced by Epo. This mechanism is regulated by the activities of both protein-tyrosine kinases and protein tyrosine phosphatases. The discovery of phosphotyrosine phosphatases that contain SH2 domains suggests roles for these molecules in growth factor signaling pathways. We found that Syp, a phosphotyrosine phosphatase, widely expressed in all tissues in mammals became phosphorylated on tyrosine after stimulation with Epo in M07ER cells engineered to express high levels of human EpoR. Syp was complexed with Grb2 in Epo-stimulated M07ER cells. Direct binding between Syp and Grb2 was also observed in vitro. Furthermore, Syp appeared to bind directly to tyrosine-phosphorylated EpoR in M07ER cells. Both NH2-terminal and COOH-terminal SH2 domains of Syp, made as glutathione S-transferase fusion proteins, were able to bind to the tyrosine-phosphorylated EpoR in vitro. These results suggest that Syp may be an important signaling component downstream of the EpoR and may regulate the proliferation and differentiation of hematopoietic cells.
Rod and cone visual cycle consequences of a null mutation in the 11-<i>cis</i>-retinol dehydrogenase gene in man (2000)

Vertebrate vision starts with photoisomerization of the 11-cis-retinal chromophore to all-trans-retinal. Biosynthesis of 11-cis-retinal is required to maintain vision. A key enzyme catalyzing the oxidation of 11-cis-retinol is 11-cis-retinol dehydrogenase (11-cis-RDH), which is encoded by the RDH5 gene. 11-cis-RDH is expressed in the RPE and not in the neural retina. The consequences of a lack of 11-cis-RDH were studied in a family with fundus albipunctatus. We identified the causative novel RDH5 mutation, Arg157Trp, that replaces an amino acid residue conserved among short-chain alcohol dehydrogenases. Three-dimensional structure modeling and in vitro experiments suggested that this mutation destabilizes proper folding and inactivates the enzyme. Studies using RPE membranes indicated the existence of an alternative oxidizing system for the production of 11-cis-retinal. In vivo visual consequences of this null mutation showed complex kinetics of dark adaptation. Rod and cone resensitization was extremely delayed following full bleaches; unexpectedly, the rate of cone recovery was slower than rods. Cones showed a biphasic recovery with an initial rapid component and an elevated final threshold. Other unanticipated results included normal rod recovery following 0.5% bleach and abnormal recovery following bleaches in the 2-12% range. These intermediate bleaches showed rapid partial recovery of rods with transitory plateaux. Pathways in addition to 11-cis-RDH likely provide 11-cis-retinal for rods and cones and can maintain normal kinetics of visual recovery but only under certain constraints and less efficiently for cone than rod function.
Flexible Reflective Color Displays using Thermochromic Pigments (2013)

This research presents a flexible reflective thermochromic display (TCD) comprised of thermochromic pigments and a patterned indium tin oxide (ITO) film coated on a polyethylene naphthalate (PEN) substrate, and the display's thermo-optical characteristics. The display showed maximum red, green, and blue reflectances of 30%, 38%, and 29%, respectively. Furthermore, the display exhibited a continuous grey color when the temperature was changed continuously. As a flexible display, the display showed reliable thermo-optical performance without image damage even when highly bent. We expect the proposed TCD will be used in outdoor information display applications where low cost is a key factor.
3D motion capture data: motion analysis and mapping to music (2002)

We report research performed on gesture analysis and mapping to music. Various movements were recorded using 3D optical motion capture. Using this system, we produced animations from movements/dance, and generate in parallel the soundtrack from the dancer&amp;apos;s movements. Prior to the actual sound mapping process, we performed various motion analyses. We present here two methods, both independent of specific orientation or location of the subject. The first deals with gestural segmentation, while the second uses pattern recognition.
Beneficial use of fibroblast growth factor 2 and RGTA, a new family of heparan mimics, for endothelialization of PET prostheses (2001)

We have studied the endothelialization of polyethylene terephtalate (PET) prostheses coated with collagen by adult human saphenous endothelial cells (EC) under various in vitro conditions. Collagenous PET was impregnated either by Fibroblast Growth Factor 2 (FGF2), heparin, a synthetic heparan sulfate mimic named RGTA 11 (for ReGeneraTing Agent), or combinations of these products. RGTA 11 belongs to a new family of drugs, which have been previously described as stabilizer and protector of heparin binding growth factors (HBGF), and to act in vivo as to stimulate wounded tissue repair. As endothelialization of prosthesis can be obtained in vivo after EC seeding and/or by transanastomotic, as well as by transprosthetic EC migrations, we have designed in vitro models to study the growth of EC seeded on PET, the EC colonization of an acellular area on PET, and the migration of EC from a collagen gel through the prosthesis. The combinations of either RGTA11 or heparin with FGF2 enhanced after a week by 5-fold the growth of seeded EC compared to RGTA or heparin alone and by 3-fold compared to FGF2 alone (p < 0.05). More than 80% of the colonization of an acellular area was achieved within 6 days when FGF2 was combined with RGTA11 or heparin. In contrast, colonization was only of 20% promoted in presence of FGF2 alone and not promoted in the presence of RGTA or heparin alone (p < 0.05). In addition, transprosthetic migration of EC and endothelialization of the luminal side were observed only when gel contained RGTA11 or heparin in combination with FGF2. The present work did strongly indicate that RGTA11 could be used in vivo as to improve endothelialization and should be the focus of continued investigation.
Disruption of CCR5-Dependent Homing of Regulatory T Cells Inhibits Tumor Growth in a Murine Model of Pancreatic Cancer (2009)

Tumors evade immune destruction by actively inducing immune tolerance through the recruitment of CD4(+)CD25(+)Foxp3(+) regulatory T cells (Treg). We have previously described increased prevalence of these cells in pancreatic adenocarcinoma, but it remains unclear what mechanisms are involved in recruiting Tregs into the tumor microenvironment. Here, we postulated that chemokines might direct Treg homing to tumor. We show, in both human pancreatic adenocarcinoma and a murine pancreatic tumor model (Pan02), that tumor cells produce increased levels of ligands for the CCR5 chemokine receptor and, reciprocally, that CD4(+) Foxp3(+) Tregs, compared with CD4(+) Foxp3(-) effector T cells, preferentially express CCR5. When CCR5/CCL5 signaling is disrupted, either by reducing CCL5 production by tumor cells or by systemic administration of a CCR5 inhibitor (N,N-dimethyl-N-{{4-{[2-(4-methylphenyl)-6,7-dihydro-5H-benzocyclohepten-8-yl]carbonyl}amino}}benzyl]-N,N-dimethyl-N- {{{4-{{{[2-(4-methylphenyl)-6,7-dihydro-5H-benzocycloheptan-8-yl]carbonyl}amino}}benzyl}}}tetrahydro-2H-pyran-4-aminiumchloride; TAK-779), Treg migration to tumors is reduced and tumors are smaller than in control mice. Thus, this study demonstrates the importance of Tregs in immune evasion by tumors, how blockade of Treg migration might inhibit tumor growth, and, specifically in pancreatic adenocarcinoma, the role of CCR5 in the homing of tumor-associated Tregs. Selective targeting of CCR5/CCL5 signaling may represent a novel immunomodulatory strategy for the treatment of cancer.
Exact dual energy material decomposition from inconsistent rays (MDIR) (2011)

At moderate computational burden, the proposed MDIR algorithm yields images of the same high quality as direct raw data-based DECT methods. In contrast to those, MDIR is applicable to the case of inconsistent rays, as it often occurs in clinical or preclinical CT. Compared to image-based methods MDIR reduces artifacts and improves mean density errors in material density images. All dual energy postprocessing methods that are in use today, such as bone removal, virtual noncontrast images, etc., can be applied to the images provided by MDIR.
You Can Make a Difference (2000)

Inaccuracies, injustices, bad advice, and insensitivity are irritating. Most of us feel powerless to do anything about such situations or don't have the time or energy to try to make changes. A strategy is described that allows the author to address her concerns. Examples are given of changes that occurred because of her efforts through writing letters. Childbirth educators become aware of policies and situations that need change; as advocates, they are encouraged to take the risk and enjoy the challenge of creating change.
Two mutations within a feline mucopolysaccharidosis type VI colony cause three different clinical phenotypes. (1998)

Mucopolysaccharidosis type VI (MPS VI) is a lysosomal storage disease caused by a deficiency of N -acetylgalactosamine-4-sulfatase (4S). A feline MPS VI model used to demonstrate efficacy of enzyme replacement therapy is due to the homozygous presence of an L476P mutation in 4-sulfatase. An additional mutation, D520N, inherited independently from L476P and recently identified in the same family of cats, has resulted in three clinical phenotypes. L476P homozygotes exhibit dwarfism and facial dysmorphia due to epiphyseal dysplasia, abnormally low leukocyte 4S/ hexosaminidase ratios, dermatan sulfaturia, lysosomal inclusions in most tissues including chondrocytes, corneal clouding, degenerative joint disease, and abnormal leukocyte inclusions. Similarly, D520N/D520N and L476P/D520N cats have abnormally low leukocyte 4S/ hexosaminidase ratios, mild dermatan sulfaturia, lysosomal inclusions in some chondrocytes, and abnormal leukocyte inclusions. However, both have normal growth and appearance. In addition, L476P/D520N cats have a high incidence of degenerative joint disease. We conclude that L476P/D520N cats have a very mild MPS VI phenotype not previously described in MPS VI humans. The study of L476P/D520N and D520N/ D520N genotypes will improve understanding of genotype to phenotype correlations and the pathogenesis of skeletal dysplasia and joint disease in MPS VI, and will assist in development of therapies to prevent lysosomal storage in chondrocytes. (
Mesoporous zirconia obtained with anionic templates (1997)

G. Pacheco, E. Zhao, A. Garcia, A. Sklyarov and J. J. Fripiat, Chem. Commun., 1997, 491 DOI: 10.1039/A607438C
Enhanced cytotoxicity of mitomycin C in human tumour cells with inducers of DT-diaphorase (1999)

DT-diaphorase is a two-electron reducing enzyme that activates the bioreductive anti-tumour agent, mitomycin C (MMC). Cell lines having elevated levels of DT-diaphorase are generally more sensitive to MMC. We have shown that DT-diaphorase can be induced in human tumour cells by a number of compounds, including 1,2-dithiole-3-thione. In this study, we investigated whether induction of DT-diaphorase could enhance the cytotoxic activity of MMC in six human tumour cell lines representing four tumour types. DT-diaphorase was induced by many dietary inducers, including propyl gallate, dimethyl maleate, dimethyl fumarate and sulforaphane. The cytotoxicity of MMC was significantly increased in four tumour lines with the increase ranging from 1.4- to threefold. In contrast, MMC activity was not increased in SK-MEL-28 human melanoma cells and AGS human gastric cancer cells, cell lines that have high base levels of DT-diaphorase activity. Toxicity to normal human marrow cells was increased by 50% when MMC was combined with 1,2-dithiole-3-thione, but this increase was small in comparison with the threefold increase in cytotoxicity to tumour cells. This study demonstrates that induction of DT-diaphorase can increase the cytotoxic activity of MMC in human tumour cell lines, and suggests that it may be possible to use non-toxic inducers of DT-diaphorase to enhance the efficacy of bioreductive anti-tumour agents.
Mass spectrometric beheviour of some 5,5‐diphenylglycocyamidine and ‐hydantoin derivatives (1975)

Abstract The mass spectra and main fragmentation pathways are presented for thirteen 1‐ and 3‐substituted 5,5‐diphenylglycocyamidine and ‐hydantoin derivatives. The principal decomposition routes of these compounds are also of diagnostic value for ascertaining positional isomerism when the substituents are eliminated in the initial stage of fragmentation.
Dehydrogenative Silylation of Ketones with a Bifunctional Organosilane by Rhodium-Pybox Catalysts (1993)

Abstract Dehydrogenative silylation of ketones with 1,2-bis(dimethylsilyl)ethane is catalyzed by a mixture of RhCl3(pybox) and AgOTf to form the corresponding silylenol ether in high yields. Only one Si-H group of 1,2-bis(dimethylsilyl)ethane is converted to the corresponding silyl enol ether.
T cell protocols : development and activation (2000)

In T Cell Protocols: Development and Activation, Kelly P. Kearse and a panel of laboratory experts describe the step-by-step execution of a wide variety of basic and specialized techniques for the study of T cell developmental biology and of their subsequent activation. Readily reproducible, the techniques are explained concisely, but in such detail that they are suitable for both the novice and experienced investigator. Coverage includes treatment of both fundamental and novel experimental protocols for the analysis of the role T cells play in immune function and in the prevention and cure of human diseases. Practical and timely, T Cell Protocols: Development and Activation offers basic scientists and clinical investigators a valuable compendium of key protocols that will improve skills with existing methods, as well as afford rapid mastery of powerful new techniques
Rifaximin (L/105), a new topical intestinal antibiotic: pharmacokinetic study after single oral administration of 3H-rifaximin to rats. (1984)

Tritiated rifaximin was administered in a single oral dose of 10 mg/kg (specific activity 8.998 microCi/mg) and 100 mg/kg (specific activity 0.786 microCi/mg) to rats. After treatment, at fixed times, the animals were sacrificed and the radioactivity in plasma, urine, feces, and in the principal organs and tissues was measured. The radioactivity present in the feces of the two groups of rats was more than 95% of the administered dose, while the amounts found in the urine ranged between 1.15% and 1.5% of the dose. In the plasma and tissues the radioactivity levels were very low. This evidence confirmed the scanty gastroenteric absorption of L/105. Furthermore, as the radioactivity levels maintained almost the same value during the trial, there was the possibility that the amounts found were in part due to isotopic exchange between tritium of 3H-L/105 and hydrogen of water.
Drugs for pain in the elderly. (1982)

Aspirin and acetaminophen are, as a rule, effective and well-tolerated compounds for use in mild pain of various etiologies. The major advantage of acetaminophen is the absence of gastrointestinal irritation. Tricyclic antidepressants, such as amitriptyline, imipramine, doxepin, and amoxapine are often given with good results to patients who manifest pain as a somatization of depression.
An international consensus statement on the management of postoperative anaemia after major surgical procedures (2018)

Despite numerous guidelines on the management of anaemia in surgical patients, there is no pragmatic guidance for the diagnosis and management of anaemia and iron deficiency in the postoperative period. A number of experienced researchers and clinicians took part in a two-day expert workshop and developed the following consensus statement. After presentation of our own research data and local policies and procedures, appropriate relevant literature was reviewed and discussed. We developed a series of best-practice and evidence-based statements to advise on patient care with respect to anaemia and iron deficiency in the postoperative period. These statements include: a diagnostic approach to iron deficiency and anaemia in surgical patients; identification of patients appropriate for treatment; and advice on practical management and follow-up that is easy to implement. Available data allow the fulfilment of the requirements of Pillar 1 of Patient Blood Management. We urge national and international research funding bodies to take note of these recommendations, particularly in terms of funding large-scale prospective, randomised clinical trials that can most effectively address the important clinical questions and this clearly unmet medical need.
Resonant Interaction of Surface Plasmons with a Dye Monolayer (1981)

Abstract Surface plasmons on silver films covered with organic monolayers (dye molecules (S 120) deposited on cadmium arachidate Scheibe or ϳ aggregate) are studied in detail. The optical properties of this system derived from reflection measurements can be described by a rather simple one electron oscillator model. The damping of its eigenfrequency is rather small due to the regular arrangement of the dye molecules. ATR measurements showed a strong influence of this narrow resonance on the dispersion relation of surface plasmons. These observations can be well described by the dielectric function derived from the reflection measurements. The dye molecules are deposited on a cadmium arachidate film of 27 Å thickness. In the case of more than one cadmium arachidate space layer between dye and metal the agreement of observed data with those calculated using the oscillator constants gets worse. This is explained by the decreasing order of the dye molecules in the ^'-aggregates with increasing number of space layers
The Pharmacokinetics and Pharmacodynamics of Propofol in a Modified Cyclodextrin Formulation (Captisol??) Versus Propofol in a Lipid Formulation (Diprivan??): An Electroencephalographic and Hemodynamic Study in a Porcine Model (2003)

A modified cyclodextrin-based formulation of propofol has been developed that may mitigate some of the problems associated with propofol in lipid emulsion. However, reformulation of propofol may change its clinical characteristics. This study in a pig model showed that the novel propofol formulation was substantially similar to the lipid emulsion propofol formulation.