gebhart/patrepeval huggingface dataset:
Seeds of Woody Plants (1992)

Journal Article Seeds of Woody Plants Get access Seeds of Woody Plants James A. Young and Cheryl G. Young Timber Press, Portland, Oregon: 1992, 525 pages, hardcover (large format), $49.95 U.S., ISBN 0-931146-21-6 James A. Young, James A. Young Search for other works by this author on: Oxford Academic PubMed Google Scholar Cheryl G. Young Cheryl G. Young Search for other works by this author on: Oxford Academic PubMed Google Scholar Tree Physiology, Volume 11, Issue 3, October 1992, Page 213, https://doi.org/10.1093/treephys/11.3.213a Published: 01 October 1992
Structure-activity relationships of anti-HIV-1 peptides with disulfide linkage between D- and L-cysteine at positions i and i+3, respectively, derived from HIV-1 gp41 C-peptide (2006)

The constrained a-helical structure of a C-peptide is useful for enhancing anti-HIV-1 activity. The i and i+3 positions in an a-helical structure are located close together, therefore D-Cys (dC) and L-Cys (C) were introduced at the positions, respectively, to make a dC-C disulfide bond in 28mer C-peptides. Accordingly, this study tested whether a dC-C disulfide bond would increase the a-helicity and anti-HIV-1 activity of peptides. A C-peptide can be divided into three domains, the N-terminal hydrophobic domain (HPD), middle interface domain (IFD), and C-terminal hydrogen domain (HGD), based on the binding property with an N-peptide. In general, the dC-C modifications in HPD enhanced the anti-HIV-1 activity, while those in IFD and HGD resulted in no or much less activity. The modified peptides with no activity clearly showed much less a-helicity than the native peptides, while those with higher activity showed an almost similar or slightly increased alpha-helicity. Therefore, the present results suggest that the introduction of a dC-C bridge in the N-terminal hydrophobic domain of a C-peptide may be useful for enhancing the anti-HIV-1 activity.
Heterogeneity-Aware Cluster Scheduling Policies for Deep Learning Workloads (2020)

Specialized accelerators such as GPUs, TPUs, FPGAs, and custom ASICs have been increasingly deployed to train deep learning models. These accelerators exhibit heterogeneous performance behavior across model architectures. Existing schedulers for clusters of accelerators, which are used to arbitrate these expensive training resources across many users, have shown how to optimize for various multi-job, multi-user objectives, like fairness and makespan. Unfortunately, existing schedulers largely do not consider performance heterogeneity. In this paper, we propose Gavel, a heterogeneity-aware scheduler that systematically generalizes a wide range of existing scheduling policies. Gavel expresses these policies as optimization problems, making it easy to optimize for objectives in a heterogeneity-aware way, while also being cognizant of performance optimizations like space sharing. Gavel then uses a round-based scheduling mechanism to ensure jobs receive their ideal allocation given the target scheduling policy. Gavel's heterogeneity-aware policies allow a heterogeneous cluster to sustain higher input load, and improve end objectives such as average job completion time and makespan by up to 3.5x compared to heterogeneity-agnostic policies.
ChemInform Abstract: PYRIMIDINES. 70. RELATIVE REACTIVITY OF THE CHLORINE ATOMS OF 2,2′,4‐TRICHLORO‐4′,5‐BIPYRIMIDINE IN THE REACTION WITH PIPERIDINE (1979)

Abstract Das beim Erhitzen des Dioxobipyrimidins (I) in siedendem Phosphoroxychlorid gebildete Trichlorbipyrimidin (II) zeigt deutliche Unterschiede bei der Substitution der einzelnen Chloratome durch Amine.
Salivacin 140, a novel bacteriocin from Lactobacillus salivarius subsp. salicinius T140 active against pathogenic bacteria (1996)

Fifteen of 353 environmental isolates of lactic acid bacteria consistently showed activity against Listeria monocytogenes, Streptococcus mutans, Actinomyces viscosus, and/or Propionibacterium acnes. Strain T140, isolated from the surface of Japanese pampas grass leaves and identified as Lactobacillus salivarius subsp. salicinius, also had activity against several Lactobacillus species, Staphylococcus aureus and Yersinia enterocolitica. Since the antagonistic factor(s) produced by T140 was sensitive to a proteolytic enzyme, it was concluded that a bacteriocin (named salivacin 140) was involved in the inhibition activity. Strain T140 required a high initial pH (7.5-8.5) in agar plates for bacteriocin production.
Design of an Automated Calibration System for Electromagnetic Tracking Systems (2008)

Electromagnetic tracking systems used in virtual reality applications are subject to tracking error due to magnetic field distortions caused by metallic objects in the environment. The goal of this research was to create and evaluate an automated data collection systems and calibration methods to allow a hands-free calibration of a complex space with multiple physical objects in the environment. The need was for a suitable device to automatically collect data points for the physical reference system without causing further distortion to the magnetic field. The calibration device was designed in order to accurately position the electromagnetic receiver at user-specified grid points throughout the tracking environment, thereby allowing the calculation of position and orientation error at each location. Novel methods were created to avoid collision of the automated calibration device with objects in the environment. The tests showed that the density of calibration and the flexibility achieved with this device far exceed any previous methods used. This research built on our previous efforts to create a software system to assist in manual data collection for calibration.
Acute stroke therapy: beyond i.v. tPA. (2002)

Although intravenous tissue plasminogen activator (i.v. tPA) has been approved for treating acute ischemic stroke, it must be given within 3 hours of stroke onset and only after ruling out hemorrhagic stroke by computed tomography. Several medical centers are turning to angiography to guide intra-arterial infusion of thrombolytic agents and mechanical endovascular interventions.
Architecting Efficient Interconnects for Large Caches with CACTI 6.0 (2008)

Interconnects play an increasingly important role in determining the power and performance characteristics of modern processors. an enhanced version of the popular CACTI tool primarily focuses on interconnect design for large scalable caches. the new version can help evaluate novel interconnection networks for cache access and accurately estimate the delay, power, and area of large caches with uniform and nonuniform access times.
Cytokine production and heterogeneity of primary stromal cells that support B lymphopoiesis (1993)

Many reports document that bone marrow stromal cells or their cytokine products can influence the formation of B cells in vitro. Most of this data comes from studies using lines or clones of stromal cells after multiple passage in culture, which could alter gene expression. Our aim in the present study was to determine which cytokines are produced by normal stromal cells under conditions that promote B lymphopoiesis. Primary cultured stromal cells were isolated on FACS from active Whitlock cultures. These cells proved to be relatively homogeneous in expression of cell surface antigens (CD44, VCAM-1, MECA10, and a molecule marked by hamster anti-mouse 8.28 monoclonal antibody). RNA from unselected Whitlock cultured adherent cells and sorted stromal cells from the same cultures were subjected to reverse transcriptase polymerase chain reaction to assess constitutive expression of several cytokine genes. Transcripts for interleukin-1 beta (IL-1 beta), IL-7, macrophage (M)-colony-stimulating factor (CSF), stem cell growth factor (SCGF), insulin-like growth factor 1 (IGF-1) and occasionally leukemia inhibitory factor were detected in RNA from intact cultures. Messages for IL-7, M-CSF, and SCGF were selectively contained within the isolated stromal cell fraction; whereas, IL-1 beta was found solely within the non-stromal cell fraction. IGF-1 was transcribed by both stromal cells and macrophages in Whitlock cultures. No evidence was found for constitutive expression of IL-1 alpha, IL-4, IL-6, or granulocyte-macrophage-CSF. This is in contrast to some reported stromal cell lines and clones. To determine if all primary stromal cells from active lymphopoietic cultures produced IL-7, the isolated cells were stained to reveal cytoplasmic IL-7 protein. A majority of the cells produced IL-7, but about 20% had no detectable IL-7 protein. Taken together, our results suggest that the primary stromal cells are a distinguishable cell type but functional subsets may exist. In regard to the differences in IL-7 production, the primary cell phenotype appears to mirror at least one division noted among the stromal cell lines.
Electron- and charge-transfer reactions within zeolites (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTElectron- and charge-transfer reactions within zeolitesKyung Byung YoonCite this: Chem. Rev. 1993, 93, 1, 321–339Publication Date (Print):January 1, 1993Publication History Published online1 May 2002Published inissue 1 January 1993https://pubs.acs.org/doi/10.1021/cr00017a015https://doi.org/10.1021/cr00017a015research-articleACS PublicationsRequest reuse permissionsArticle Views1682Altmetric-Citations283LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Comparison of edge analysis techniques for the determination of the MTF of digital radiographic systems (2005)

The modulation transfer function (MTF) is well established as a metric to characterize the resolution performance of a digital radiographic system. Implemented by various laboratories, the edge technique is currently the most widespread approach to measure the MTF. However, there can be differences in the results attributed to differences in the analysis technique employed. The objective of this study was to determine whether comparable results can be obtained from different algorithms processing identical images representative of those of current digital radiographic systems. Five laboratories participated in a round-robin evaluation of six different algorithms including one prescribed in the International Electrotechnical Commission (IEC) 62220-1 standard. The algorithms were applied to two synthetic and 12 real edge images from different digital radiographic systems including CR, and direct- and indirect-conversion detector systems. The results were analysed in terms of variability as well as accuracy of the resulting presampled MTFs. The results indicated that differences between the individual MTFs and the mean MTF were largely below 0.02. In the case of the two simulated edge images, all algorithms yielded similar results within 0.01 of the expected true MTF. The findings indicated that all algorithms tested in this round-robin evaluation, including the IEC-prescribed algorithm, were suitable for accurate MTF determination from edge images, provided the images are not excessively noisy. The agreement of the MTF results was judged sufficient for the measurement of the MTF necessary for the determination of the DQE.
Cobalt(ii) single-molecule magnets (2010)

This short tutorial review covers recent progress in the field of polynuclear cobalt(ii)-based complexes, which display slow magnetic relaxation at low temperature. Cobalt(ii) single-molecule magnets (SMMs) can display much larger magnetic anisotropies and hence, potentially higher blocking temperatures than SMMs based on ions where the zero-field splitting originates from a second order spin-orbit coupling, such as manganese(iii).
Analysis of a Ferric Uptake Regulator (Fur) Mutant of <i>Desulfovibrio vulgaris</i> Hildenborough (2007)

Previous experiments examining the transcriptional profile of the anaerobe Desulfovibrio vulgaris demonstrated up-regulation of the Fur regulon in response to various environmental stressors. To test the involvement of Fur in the growth response and transcriptional regulation of D. vulgaris, a targeted mutagenesis procedure was used for deleting the fur gene. Growth of the resulting Deltafur mutant (JW707) was not affected by iron availability, but the mutant did exhibit increased sensitivity to nitrite and osmotic stresses compared to the wild type. Transcriptional profiling of JW707 indicated that iron-bound Fur acts as a traditional repressor for ferrous iron uptake genes (feoAB) and other genes containing a predicted Fur binding site within their promoter. Despite the apparent lack of siderophore biosynthesis genes within the D. vulgaris genome, a large 12-gene operon encoding orthologs to TonB and TolQR also appeared to be repressed by iron-bound Fur. While other genes predicted to be involved in iron homeostasis were unaffected by the presence or absence of Fur, alternative expression patterns that could be interpreted as repression or activation by iron-free Fur were observed. Both the physiological and transcriptional data implicate a global regulatory role for Fur in the sulfate-reducing bacterium D. vulgaris.
High Molecular Weight Plant Polyphenolics (Tannins) as Biological Antioxidants (1998)

Representative condensed and hydrolyzable tannins and related simple phenolics were evaluated as biological antioxidants using cyclic voltammetry, the metmyoglobin assay, and the deoxyribose assay. The redox potentials of the tannins were similar to those of structurally related simple phenolics. However, the tannins were 15-30 times more effective at quenching peroxyl radicals than simple phenolics or Trolox. One of the tannins, polygalloyl glucose, reacted an order of magnitude more quickly with hydroxyl radical than mannitol. These results suggest that tannins, which are found in many plant-based foods and beverages, are potentially very important biological antioxidants.
Document structure extraction for interactive document retrieval systems (1993)

We have developed an automatic document structure extraction system for interactive document R trieval.'l%esystemmalizes inefficient and dynamic fall-text retrieval system.By analyzing document
Stability and bifurcations of periodically modulated, optically injected laser diodes (2001)

Recent experiments using lasers subject to external injection [T. B. Simpson, Opt. Commun., 170, 93 (1999)] have shown remarkable locking performances when a small reference current modulation is added to the dc-bias current. The locking problem is studied analytically by using a multiple scale perturbation method. We derive a slow time amplitude equation for the laser rapid limit-cycle oscillations. The solution of this equation is then investigated both analytically and numerically using a continuation method. We find that the intensity of the laser field can be time periodic (locking) or quasiperiodic (unlocking) and that there exist two distinct bifurcation mechanisms leading to locking. Finally, we compare bifurcation diagrams based on our amplitude equation with diagrams obtained from the laser original equations and find a good quantitative agreement.
Absolute Fiber-Optic Linear Position and Displacement Sensor (1997)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text G. Duplain, C. Belleville, S. Bussière, and P. A. Bélanger, "Absolute Fiber-Optic Linear Position and Displacement Sensor," in 12th International Conference on Optical Fiber Sensors, Vol. 16 of 1997 OSA Technical Digest Series (Optica Publishing Group, 1997), paper OTuD5. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Visible and near infrared reflectance characteristics of dry plant materials (1990)

Abstract Laboratory reflectance spectra of dry plant materials are distinctly different from green plant materials. The dry plant materials have diagnostic ligno-cellulose absorption features at 2·09 and in the 2·3μm region. The visible portion of spectrum is dominated by an absorption wing produced by intense blue and UV absorption. This absorption wing breaks down as plant decay progresses.
A prospective, randomised comparative study of weekly versus biweekly application of dehydrated human amnion/chorion membrane allograft in the management of diabetic foot ulcers (2014)

The aim of this study is to determine if weekly application of dehydrated human amnion/chorion membrane allograft reduce time to heal more effectively than biweekly application for treatment of diabetic foot ulcers. This was an institutional review board-approved, registered, prospective, randomised, comparative, non-blinded, single-centre clinical trial. Patients with non-infected ulcers of ≥ 4 weeks duration were included for the study. They were randomised to receive weekly or biweekly application of allograft in addition to a non-adherent, moist dressing with compressive wrapping. All wounds were offloaded. The primary study outcome was mean time to healing. Overall, during the 12-week study period, 92·5% (37/40) ulcers completely healed. Mean time to complete healing was 4·1 ± 2·9 versus 2·4 ± 1·8 weeks (P = 0·039) in the biweekly versus weekly groups, respectively. Complete healing occurred in 50% versus 90% by 4 weeks in the biweekly and weekly groups, respectively (P = 0·014). Number of grafts applied to healed wounds was similar at 2·4 ± 1·5 and 2·3 ± 1·8 for biweekly versus weekly groups, respectively (P = 0·841). These results validate previous studies showing that the allograft is an effective treatment for diabetic ulcers and show that wounds treated with weekly application heal more rapidly than with biweekly application. More rapid healing may decrease clinical operational costs and prevent long-term medical complications.
Cerebral amyloid deposition and diffuse plaques in ``normal'' aging (1996)

The presence of senile plaques in the neocortex of apparently nondemented elderly persons often is accepted as part of "normal" aging. Alternatively, because cerebral deposition of beta-amyloid may be a key mechanism in the development of Alzheimer's disease (AD), the presence of beta-amyloid-containing plaques may represent very early AD. To examine the relationships of cognitively normal aging, very mild dementia of the Alzheimer type, and the presence of neocortical senile plaques, we performed clinicopathologic correlation in 21 longitudinally studied healthy elderly subjects (84.5 +/- 6.6 years old at death). Nine subjects had strikingly high plaque densities in the neocortex; two of these subjects died of head injury before which there was no evidence of cognitive impairment. The other seven subjects with high plaque densities had clinical evidence for very mild cognitive impairment (Clinical Dementia Rating score of 0.5) at some time during their course and mildly impaired psychometric performance at last assessment before death. The remaining 12 subjects had no clinical or psychometric impairment and had few or no neocortical AD lesions. These results suggest that senile plaques may not be part of normal aging but instead represent presymptomatic or unrecognized early symptomatic AD. The high density of senile plaques (predominately of the diffuse subtype) in the cortex of subjects just at the threshold of detectable dementia is consistent with the hypothesis that beta-amyloid deposition is an initial pathogenetic event in the development of AD.
Exosomes Derived from Hypoxic Leukemia Cells Enhance Tube Formation in Endothelial Cells (2013)

Hypoxia plays an important role during the evolution of cancer cells and their microenvironment. Emerging evidence suggests communication between cancer cells and their microenvironment occurs via exosomes. This study aimed to clarify whether hypoxia affects angiogenic function through exosomes secreted from leukemia cells. We used the human leukemia cell line K562 for exosome-generating cells and human umbilical vein endothelial cells (HUVECs) for exosome target cells. Exosomes derived from K562 cells cultured under normoxic (20%) or hypoxic (1%) conditions for 24 h were isolated and quantitated by nanoparticle tracking analysis. These exosomes were then cocultured with HUVECs to evaluate angiogenic activity. The exosomes secreted from K562 cells in hypoxic conditions significantly enhanced tube formation by HUVECs compared with exosomes produced in normoxic conditions. Using a TaqMan low-density miRNA array, we found a subset of miRNAs, including miR-210, were significantly increased in exosomes secreted from hypoxic K562 cells. We demonstrated that cancer cells and their exosomes have altered miRNA profiles under hypoxic conditions. Although exosomes contain various molecular constituents such as proteins and mRNAs, altered exosomal compartments under hypoxic conditions, including miR-210, affected the behavior of endothelial cells. Our results suggest that exosomal miRNA derived from cancer cells under hypoxic conditions may partly affect angiogenic activity in endothelial cells.
Effect of prostaglandin F-2α on plasma levels of progesterone and pregnenolone in the hysterectomized guinea-pig (1979)

Summary. Repeated injections of PGF-2α were given to hysterectomized guinea-pigs. Within 12 h after the first injection, plasma progesterone levels were significantly reduced (P &amp;lt; 0·001) and declined to &amp;lt;1 ng/ml by the 4th day after the end of PGF-2α treatment. A decline in plasma levels of pregnenolone paralleled that of progesterone. PGF-2α treatment did not affect the metabolic clearance rate of [3H]pregnenolone, but the conversion of [3H]pregnenolone to [3H]progesterone was reduced by about 50%.