gebhart/patrepeval huggingface dataset:
The Role of Groundwater Recharge in Wastewater Reuse: Israel's Dan Region Project (1980)

Groundwater recharge with tertiary effluent via spreading basins is practiced in the Dan region project for indirect reuse of municipal wastewater from the Tel Aviv metropolitan area. In addition to effluent treatment, groundwater recharge provides seasonal and multiannual storage, ensures economic as well as psychological merits, and enhances the reliability of the reclamation system.
[The observation of the acute toxicity of the lanthanum and cerium to the buccal mucosa and systemic conditions of mice] (1998)

OBJECTIVE:The present study was to investigate the systemic and local acute toxicity of the lanthanum(La) and cerium(Ce) to the mice. METHODS: 0.2% and 1% La and Ce solutions were applied to buccal mucoa of mice.The systemic conditions and local histopathological changes were observed. RESULTS: The mice hadn't any systemic acute toxic reactions. Histological observation found that mucosal structures of most mice were almost normal,only a few mice showed the slight inflammation,but there were no significant differences between experimental and control groups. CONCLUSION: It was safe for local use of 0.2%,1% La and Ce to the buccal mucosa of mice. La and Ce may become a kind of safe caries-preventive drugs for local application.
Mass spectrometry of 1-substituted adamantanes. Effect of functional groups on the primary fragmentation pathways (1973)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMass spectrometry of 1-substituted adamantanes. Effect of functional groups on the primary fragmentation pathwaysK. K. Khullar, Charles L. Bell, and Ludwig BauerCite this: J. Org. Chem. 1973, 38, 5, 1042–1044Publication Date (Print):March 1, 1973Publication History Published online1 May 2002Published inissue 1 March 1973https://pubs.acs.org/doi/10.1021/jo00945a036https://doi.org/10.1021/jo00945a036research-articleACS PublicationsRequest reuse permissionsArticle Views137Altmetric-Citations14LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Quit Now! A Psychoeducational Expressive Therapy Group Work Approach for At-Risk and Delinquent Adolescent Smokers in Singapore (2011)

In this article, we review the risk and protective factors for adolescent smoking, as well as current research on evidence-based practices. The relevance of structured expressive therapy in meeting the maturational and emotional needs of at-risk and delinquent adolescents, and the multicultural context of adolescents in Singapore's Asian society are also explored. We present a framework for an evidence-based psychoeducational structured expressive therapy group work model which was pioneered in Singapore residential rehabilitation programs and high schools under the auspices of CARE Singapore.
Compiler-assisted, selective out-of-order commit (2012)

This paper proposes an out-of-order instruction commit mechanism using a novel compiler/architecture interface. The compiler creates instruction “blocks” guaranteeing some commit conditions and the processor uses the block information to commit certain instructions out of order. Micro-architectural support for the new commit mode is made on top of the standard, ROB-based processor and includes out-of-order instruction commit with register and load queue entry release. The commit mode may be switched multiple times during execution. Initial results for a 4-wide processor show that, on average, 52% instructions are committed out of order resulting in 10% to 26% speedups over in-order commit, with minimal hardware overhead. The performance improvement is a result of an effectively larger instruction window that allows more cache misses to be overlapped for both L1 and L2 caches.
Accurate, Robust, and Flexible Real-time Hand Tracking (2015)

We present a new real-time hand tracking system based on a single depth camera. The system can accurately reconstruct complex hand poses across a variety of subjects. It also allows for robust tracking, rapidly recovering from any temporary failures. Most uniquely, our tracker is highly flexible, dramatically improving upon previous approaches which have focused on front-facing close-range scenarios. This flexibility opens up new possibilities for human-computer interaction with examples including tracking at distances from tens of centimeters through to several meters (for controlling the TV at a distance), supporting tracking using a moving depth camera (for mobile scenarios), and arbitrary camera placements (for VR headsets). These features are achieved through a new pipeline that combines a multi-layered discriminative reinitialization strategy for per-frame pose estimation, followed by a generative model-fitting stage. We provide extensive technical details and a detailed qualitative and quantitative analysis.
Stimulation of the wrist acupuncture point P6 for preventing postoperative nausea and vomiting (2009)

P6 acupoint stimulation prevented PONV. There was no reliable evidence for differences in risks of postoperative nausea or vomiting after P6 acupoint stimulation compared to antiemetic drugs.
Use of Viscogens, dNTPαS, and Rhodium(III) as Probes in Stopped-Flow Experiments To Obtain New Evidence for the Mechanism of Catalysis by DNA Polymerase β<sup>,</sup> (2005)

The kinetic mechanism and the structural bases of the fidelity of DNA polymerases are still highly controversial. Here we report the use of three probes in the stopped-flow studies of Pol beta to obtain new, direct evidence for our previous interpretations: (a) Increasing the viscosity of the reaction buffer by sucrose or glycerol is expected to slow down the conformational change differentially, and it was shown to slow down the first (fast) fluorescence transition selectively. (b) Use of dNTPalphaS in place of dNTP is expected to slow down the chemical step preferentially, and it was shown to slow down the second (slow) fluorescence transition selectively. (c) The substitution-inert Rh(III)dNTP was used to show for the first time that the slow fluorescence change occurs after mixing of Pol beta.DNA.Rh(III)dNTP with Mg(II). These results, along with crystal structures, suggest that the subdomain-closing conformational change occurs before binding of the catalytic Mg(II) while the rate-limiting step occurs after binding of the catalytic Mg(II). These results provide new evidence to the mechanism we suggested previously, but do not support the results of three recent papers of computational studies. The results were further supported by a "sequential mixing" stopped-flow experiment that used no analogues, and thus ruled out the possibility that the discrepancy between experimental and computational results is due to the use of analogues. The methodologies can be used to examine other DNA polymerases to answer whether the properties of Pol beta are exceptional or general.
&lt;title&gt;Novel methods for simultaneous strain and temperature measurements with optical fiber Bragg gratings&lt;/title&gt; (1999)

We report on feasibility studies of two new approaches for simultaneous strain and temperature measurements with optical fiber Bragg gratings. In sensor applications fiber Bragg gratings cannot be thermally isolated. Therefore temperature has to be compensated or measured simultaneously with the measurand of interest. In strain sensing this is often done by measuring the wavelength response of a second Bragg grating attached to an unstrained sample specimen and comparing its response to response of the strained sample. This method is very accurate. However, often it is not possible or difficult to have unstrained samples, e.g., in rockbolt anchors with embedded fiber Bragg gratings. We propose two new simultaneous measurement concepts and compare them to known concepts. The first investigated method uses the different sensitivities to strain and temperature of the main peak of a Bragg grating in transmission compared to the back-reflected cladding modes. We will present first results of simultaneous strain and temperature measurements over a range from 2 degrees Celsius to 95 degrees Celsius up to 3500 micrometer/m in strain. This method leads to a combined resolution in temperature and strain of 4 degrees Celsius and 35 micrometer, respectively. The second method is based on two low reflectivity gratings. They are in close vicinity to each other in the fiber. Both have a small refractive index modulation of about 2 (DOT) 10<SUP>-4</SUP>, but one was homogeneously post-illuminated and has an increased mean refractive index. We will present first results indicating that the additional UV-illumination changes temperature- and strain-sensitivity of the post-illuminated Bragg grating slightly.
Morpholino Antisense Oligomers: Design, Preparation, and Properties (1997)

Antisense promised major advances in treating a broad range of intractable diseases, but in recent years progress has been stymied by technical problems, most notably inadequate specificity, ineffective delivery into the proper subcellular compartment, and unpredictable activity within cells. Herein is an overview of the design, preparation, and properties of Morpholino oligos, a novel antisense structural type that solves the sequence specificity problem and provides high and predictable activity in cells. Morpholino oligos also exhibit little or no nonantisense activity, afford good water solubility, are immune to nucleases, and are designed to have low production costs.
Effects of Vascular Endothelial Growth Factor on Hemodynamics and Cardiac Performance (1996)

Vascular endothelial growth factor (VEGF), a major regulator of angiogenesis, has therapeutic benefit in animal models of coronary or limb ischemia. However, the hemodynamic effects of VEGF have not been investigated. We examined the effects of VEGF on hemodynamics and cardiac performance. Mean arterial pressure (MAP), heart rate (HR), cardiac output, stroke volume, left ventricular (LV) dP/dt, and hematocrit were measured before and after intravenous injection of VEGF in conscious, instrumented rats. VEGF caused a dose-dependent reduction in MAP and an associated increase in HR. VEGF (250 micrograms/kg) significantly decreased cardiac output and stroke volume without affecting the inotropic state of the left ventricle, as determined by dP/dt. VEGF significantly increased hematocrit. Furthermore, VEGF did not affect contractility or HR in the isolated rat heart in vitro. The data suggest that the VEGF-induced decrease in cardiac output is due to reduced stroke volume, which may be caused by a decrease in venous return rather than a direct effect on myocardial contractility. In addition, pretreatment with N omega-nitro-L-arginine methyl-ester (L-NAME), a nitric oxide (NO) synthase inhibitor, significantly attenuated the depressor and tachycardic responses to VEGF, suggesting that VEGF-induced hypotension may be mediated by NO.
Human NK Cells in Health and Disease: Clinical, Functional, Phenotypic and DNA Genotypic Characteristics (1992)

Natural killer (NK) cells are the subject of great current interest because of their possible (in vivo) role in tumour cell surveillance and killing, and because of the potential application of cytokine-modulated NK cells in cancer immunotherapy. In addition, clonal proliferations of NK-associated (NKa) cell populations represent a high proportion of chronic (non-B) lymphoid malignancies and abnormal (both clonal and non-clonal) NKa components are being increasingly reported in association with diverse clinical pictures such as autoimmune disease. This communication extensively reviews what is presently known regarding normal and leukaemic NKa phenotypic diversity, the mechanisms of NK-mediated cytolysis, the role of NK cells in malignancy, and the diagnostic and cellular aspects of malignant NKa proliferations.
Coiled-coil protein composition of 22 proteomes – differences and common themes in subcellular infrastructure and traffic control (2005)

MultiCoil predicts proteins with extended coiled-coil domains (more than 250 amino acids) to be largely absent from bacterial genomes, but present in archaea and eukaryotes. The structural maintenance of chromosomes proteins and their relatives are the only long coiled-coil protein family clearly conserved throughout all kingdoms, indicating their ancient nature. Motor proteins, membrane tethering and vesicle transport proteins are the dominant eukaryote-specific long coiled-coil proteins, suggesting that coiled-coil proteins have gained functions in the increasingly complex processes of subcellular infrastructure maintenance and trafficking control of the eukaryotic cell.
Resonant Raman spectroscopy on InN (2005)

Abstract The novel use of resonant Raman spectroscopy to elucidate the band gap of InN is illustrated in a study of MBE‐grown films. This technique can distinguish between electronic transitions related to the InN from transitions related to defects and impurities that are so typical for current InN material. Using excitation energies from 1.49 eV (830 nm) to 2.54 eV (488 nm), we identify a critical point in the InN band structure within ≈200–300 meV below 1.5 eV. The origin of this critical point, whether band gap or higher critical point, is discussed. Furthermore, Raman results are presented on the temperature dependence of the InN phonons. Analysis of the data provides information on phonon lifetimes and decay mechanisms, important to assess whether hot phonon effects need to be considered in future InN devices. (© 2005 WILEY‐VCH Verlag GmbH &amp; Co. KGaA, Weinheim)
Opinion: phones down, for literacy's sake (2016)

As adults, what do we expect from children when we talk with them? Should we expect their close attention and active engagement in return? Do we wish that they'd put down their electronic device so we could talk with them without distractions? And how often do we stop to consider what we are modelling for them ourselves?
Cytokine targeting in tumors using a bispecific antibody directed against carcinoembryonic antigen and tumor necrosis factor alpha. (1996)

The use of tumor necrosis factor alpha (TNFalpha) in cancer therapy is limited by its short circulatory half-life and its severe systemic side effects. To overcome these limitations, we evaluated the capability of a bispecific antibody (BAb) directed against carcinoembryonic antigen (CEA) and human TNFalpha to target this cytokine in tumors. A BAb was constructed by coupling the Fab' fragments from an anti-CEA monoclonal antibody (MAb) to the Fab' fragments from an anti-TNFalpha MAb via a stable thioether linkage. The double specificity of the BAb for CEA and TNFalpha was demonstrated using a BIAcoreTM two-step analysis. The affinity constants of the BAb for CEA immobilized on a sensor chip and for soluble TNFalpha added to the CEA-BAb complex were as high as those of the parental MAbs (1.7 x 10(9) M-1 and 6.6 x 10(8) M-1, respectively). The radiolabeled 125I-labeled BAb retained high immunoreactivity with both CEA and TNFalpha immobilized on a solid phase. In nude mice xenografted with the human colorectal carcinoma T380, the 125I-labeled BAb showed a tumor localization and biodistribution comparable to that of 131I-labeled anti-CEA parental F(ab')2 with 25-30% of the injected dose (ID)/g tumor at 24 h and 20% ID/g tumor at 48 h. To target TNFalpha to the tumor, a two-step i.v. injection protocol was used first, in which a variable dose of 125I-labeled BAb was injected, followed 24 or 48 h later by a constant dose of 131I-labeled TNFalpha (1 microg). Mice pretreated with 3 microg of BAb and sacrificed 2, 4, 6, or 8 h after the injection of TNFalpha showed a 1.5- to 2-fold increased concentration of 131I-labeled TNFalpha in the tumor as compared to control mice, which received TNFalpha alone. With a higher dose of BAb (25 microg), mice showed a better targeting of TNFalpha with a 3.2-fold increased concentration of 131I-labeled TNFalpha in the tumor: 9.3% versus 2.9% ID/g in control mice 6 h after TNFa injection. In a one-step injection protocol using a premixed BAb-TNFalpha preparation, similar results were obtained 6 h postinjection (3.5-fold increased TNFalpha tumor concentration). A longer retention time of TNFalpha was observed leading to an 8.1-fold increased concentration of TNFalpha in the tumor 14 h postinjection (4.4 versus 0.5% ID/g tumor for BAb-treated and control mice, respectively). These results show that our BAb is able, first, to localize in a human colon carcinoma and, there, to immunoabsorb the i.v.-injected TNFalpha, leading to its increased concentration at the tumor site.
A study of the ring-opening of lactides and related cyclic esters by Ph<sub>2</sub>SnX<sub>2</sub>and Ph<sub>3</sub>SnX compounds (X = NMe<sub>2</sub>, OR) (2003)

Ph3SnX reacts with L-lactide in the order X = NMe2 ∼ OMe ≫ OPri > OBut in the initial ring-opening event. The rate of ring-opening of methyl substituted 1,4-dioxane-2,5-diones decreases with methyl substitution and ring-opening of 3,3,6,6-tetramethyl-1,4-dioxane-2,5-dione is not observed. From studies of the reaction between Ph3SnOPri and L-lactide the activation parameters ΔH≠ = 13(1) kcal mol−1 and ΔS≠ = −37(3) eu have been determined. Ph3SnNMe2 reacts with cyclic esters and propylene carbonate at low temperatures to give isolable ring-opened products. The compound Ph3Sn[OCHMeC(O)OCHMeC(O)X] (where X = NMe2, OMe) are labile in solution at room temperature, yielding Ph3Sn[OCHMeC(O)X] and Ph3Sn[OCHMeC(O)]nX, where n ≥ 3, by transesterification, along with other minor products due to phenyl/OR group transfer (i.e., Ph4Sn). Ph2Sn(NMe2)2 and L-lactide react to give Ph2Sn[OCHMeC(O)NMe2]2 by ring-opening of L-lactide followed by rapid amidation. A related compound, Ph2Sn[OCHMeC(O)OPri]2, is also formed in the reaction between Ph2Sn(OPri)2 and L-lactide but is more labile toward further ring-opening of L-lactide.
A Vehicle Number to Predict Tractive Performance (1995)

Tractor tractive performance is traditionally predicted by summing the performance of individual tires. This process requires iteration to determine dynamic load on each tire. A vehicle number, Vn, for all-wheel drive vehicles was calculated from static front and rear mobility numbers and static axle loads as a simplified method of describing tractor and traction surface interaction. Results of predicting the dynamic traction ratio with the Vn and Brixius methods were compared for two tractor chassis types. Three vehicle loads, load distributions, and soil conditions give a total of 27 conditions to evaluate the proposed prediction method for each of the two tractor chassis types. The results indicate that Vn is adequate to predict tractor and traction surface interaction in the situations considered. A method of addressing the differences of two-wheel drive tractors and limits of applicability will need to be developed.
BLAST 2 Sequences, a new tool for comparing protein and nucleotide sequences (1999)

'BLAST 2 Sequences', a new BLAST-based tool for aligning two protein or nucleotide sequences, is described. While the standard BLAST program is widely used to search for homologous sequences in nucleotide and protein databases, one often needs to compare only two sequences that are already known to be homologous, coming from related species or, e.g. different isolates of the same virus. In such cases searching the entire database would be unnecessarily time-consuming. 'BLAST 2 Sequences' utilizes the BLAST algorithm for pairwise DNA-DNA or protein-protein sequence comparison. A World Wide Web version of the program can be used interactively at the NCBI WWW site (http://www.ncbi.nlm.nih.gov/gorf/bl2.++ +html). The resulting alignments are presented in both graphical and text form. The variants of the program for PC (Windows), Mac and several UNIX-based platforms can be downloaded from the NCBI FTP site (ftp://ncbi.nlm.nih.gov).
Video-Based Traffic Flow Parameters Monitoring and Integrated Traffic Information System (2013)

Road traffic flow parameters are the important basic information for traffic safety management, traffic condition evaluation and decision-making. This project designs a video-based traffic flow parameters monitoring terminal (ITS monitoring terminal), which is based on MENLOW embedded platform and expands its hardware and software resources. CCD cameras are used to capture image in video sequences in traffic environment. Image processing and analysis technologies are used to track vehicles and analyze the vehicle conditions in real time, and a vision measurement model which computes the traffic flow parameters, such as length, width, speed, distance between two vehicles, traffic flow density, and occupancy ratios, etc. is constructed. Furthermore, BP neural network is used to classify vehicles. ITS terminals interconnected with each other through public network or private network (optical ring network of transport agency, WLAN, Internet, and 3G) and connected with monitoring center of transport agency, which achieves dynamic data exchange and share among ITS terminals. It realized a wide-area distributed and integrated transport information system which synthesizes transport information guidance, traffic tracking; condition evaluation, decision-making, and real time transport information release.
BSIM3V3 MOSFET MODEL (1998)

The BSIM3v3 compact MOSFET model is reviewed. It is a physics-based model that is accurate, smooth, continuous, scalable, predictive and computationally robust over different regions of operation and a wide geometry range. BSIM3v3 considers all major physical effects in deep submicron MOSFETs, making it a good base for future sub-0.1m device models and for statistical circuit designs. A key feature of the model lies in its thorough, accurate and functional mathematical representation of MOS device physics, which has made BSIM3v3 selected by an international consortium of semiconductor companies as the first industry standard MOSFET model.
Efficient type-ahead search on relational data (2009)

Existing keyword-search systems in relational databases require users to submit a complete query to compute answers. Often users feel "left in the dark" when they have limited knowledge about the data, and have to use a try-and-see approach for modifying queries and finding answers. In this paper we propose a novel approach to keyword search in the relational world, called Tastier. A Tastier system can bring instant gratification to users by supporting type-ahead search, which finds answers "on the fly" as the user types in query keywords. A main challenge is how to achieve a high interactive speed for large amounts of data in multiple tables, so that a query can be answered efficiently within milliseconds. We propose efficient index structures and algorithms for finding relevant answers on-the-fly by joining tuples in the database. We devise a partition-based method to improve query performance by grouping highly relevant tuples and pruning irrelevant tuples efficiently. We also develop a technique to answer a query efficiently by predicting the highly relevant complete queries for the user. We have conducted a thorough experimental evaluation of the proposed techniques on real data sets to demonstrate the efficiency and practicality of this new search paradigm.