gebhart/patrepeval huggingface dataset:
Effect of Postharvest Ultraviolet Irradiation on Resveratrol and Other Phenolics of Cv. Napoleon Table Grapes (2000)

In the skin of cv. Napoleon table grapes, the anthocyanins malvidin 3-glucoside (and its acetyl and p-coumaroyl derivatives), cyanidin 3-glucoside, peonidin 3-glucoside, cyanidin 3-glucoside, petunidin 3-glucoside, and delphinidin 3-glucoside were identified by HPLC-DAD-MS. In addition, quercetin 3-glucoside and 3-glucuronide, caffeoyltartaric, piceid, and resveratrol were also detected. The content of most phenolics remained quite constant during postharvest refrigerated storage (10 days at 0 degrees C) while the resveratrol derivatives increased 2-fold. Postharvest treatments of grapes with UVC and UVB light induced a large increase in resveratrol derivatives (3- and 2-fold, respectively). This means that a serving of mature Napoleon grapes (200 g) provides approximately 1 mg of resveratrol, which is in the range of the amount supplied by a glass of red wine. This can be increased to 2 or 3 mg of resveratrol per serving in grapes that have been irradiated with UVB or UVC, respectively. These results show that refrigerated storage and UV irradiation of table grapes can be beneficial in terms of increasing the content of potentially health-promoting phenolics.
Architecture of a protein central to iron homeostasis: crystal structure and spectroscopic analysis of the ferric uptake regulator (2003)

Iron is an essential element for almost all organisms, although an overload of this element results in toxicity because of the formation of hydroxyl radicals. Consequently, most living entities have developed sophisticated mechanisms to control their intracellular iron concentration. In many bacteria, including the opportunistic pathogen Pseudomonas aeruginosa, this task is performed by the ferric uptake regulator (Fur). Fur controls a wide variety of basic physiological processes including iron uptake systems and the expression of exotoxin A. Here, we present the first crystal structure of Fur from P. aeruginosa in complex with Zn2+ determined at a resolution of 1.8 A. Furthermore, X-ray absorption spectroscopic measurements and microPIXE analysis were performed in order to characterize the distinct zinc and iron binding sites in solution. The combination of these complementary techniques enables us to present a model for the activation and DNA binding of the Fur protein.
Characterization of RuO2 Thin Films Prepared by Hot‐Wall Metallorganic Chemical Vapor Deposition (1997)

thin films were deposited on substrate at low temperatures by hot‐wall metallorganic chemical vapor deposition using the ruthenocene and oxygen gas mixtures. The preferred orientation of films varied from (200) to (101) as the film thickness increases above 150 nm irrespective of the deposition conditions. deposition reaction was controlled by gas‐phase mass‐transfer in these experiments. The film resistivity increased with increasing oxygen flow rates. The increase of film resistivity with increasing oxygen flow rates was due to the contribution of carrier concentration rather than that of carrier mobility. The film resistivity with increasing the annealing temperatures decreased because of densification of films.
Comfortably numb in the intensive care unit* (2006)

Department of Critical Care Medicine, Neurovascular ICU, University of Pittsburgh Medical Center, Pittsburgh, PA The author has no financial interests to disclose.
Vertical-cavity surface-emitting lasers integratedonto silicon substrates by PdGe contacts (1994)

Vertical-cavity surface-emitting lasers (VCSELs) have been integrated onto an aluminium coated silicon substrate. The InGaAs top-emitting VCSELs were grown by molecular beam epitaxy and individual lasers were defined by high energy proton implantation. The substrate was removed by a new substrate removal process and the lasers were bonded to an aluminised silicon substrate using a Pd/Ge/InSn contact. Threshold currents below 5.5 mA and output powers of ~1 mW were obtained for 40 µm VCSELs bonded to Si.
Biotin radioligand assay with an 125I-labeled biotin derivative, avidin, and avidin double-antibody reagents. (1987)

We describe a new radioligand assay for determining biotin in biological fluids by using a mixture of N-[beta-(4-OH-3-125I-phenyl)ethyl]- and N-[beta-(4-OH-3,5-di-125I-phenyl)ethyl]biotinamides as radiotracer, avidin as a binding protein, and an avidin double-antibody as a separation reagent. The radiotracer is synthesized by coupling (at pH 8.5, 20-22 degrees C, 90 min) N-hydroxysuccinimidobiotin to radioiodinated tyramine. The assay curve is linear and the assay itself is sensitive (less than 10 ng/L), reproducible (intra- and interassay CVs 4.1% and 7.0%, respectively), and allows the simultaneous handling of more than 100 samples in less than 4 h. Serum samples from apparently normal subjects contained 100-840 ng of biotin per liter (mean 340 ng/L). Pregnant women had low concentrations of biotin (100-300 ng/L) in their serum. Patients undergoing chronic hemodialysis treatment showed high concentrations (0.5-3.0 micrograms/L), which may be ascribable to the inability of avidin, which was used as the assay binding protein, to distinguish biotin from biotinyl derivatives with an intact ureido ring.
Automatic SAR Simulation Technique for Object Identification in Complex Urban Scenarios (2013)

Most of the existing SAR simulators provide simulated images only for visual interpretation. This paper presents a new approach for supporting the automatic interpretation of meter resolution SAR images in complex urban scenarios. To this end, an automatic system for generating and geocoding of simulated images has been developed, based on the SAR simulator RaySAR and digital surface models as geometric information for urban scenes. Various simulated images and different layers (layover, shadow, double bounce, and ground) are generated for the whole scene as well as for individual buildings, with consideration of neighborhood influences. The proposed approach is tested on an area in central Munich with a LiDAR digital surface model as the input. The simulated images are compared with a TerraSAR-X spotlight image and show good geocoding accuracy, reasonable mask layers, and precise individual building layover contours.
In Fibroblasts Vegf-D Expression Is Induced by Cell-Cell Contact Mediated by Cadherin-11 (2001)

Vascular endothelial growth factors (VEGFs) are a highly conserved family of growth factors all angiogenic in vivo with mitogenic and chemotactic activity on endothelial cells. VEGFs are expressed in fibroblasts either in hypoxia or in response to growth factors. Here we report that, differently from the other members of the family, Vegf-D is induced by cell-cell contact. By in situ hybridization we demonstrated that noninteracting fibroblasts express low levels of Vegf-D mRNA, whereas contacting cells express high levels of Vegf-D transcripts. By immunostaining we observed that the surface protein cadherin-11 is localized at the opposite sites of interacting cell surfaces. Ca(2+) deprivation from the culture medium determined the loss of cadherin-11 from the cell surfaces and down-regulation of Vegf-D mRNA. Moreover, a cadherin-11 antisense RNA construct inhibited Vegf-D expression in confluent BALB/c fibroblasts, whereas in NIH 3T3 cells, which express low levels of cadherin-11, Vegf-D induction could be obtained by overexpression of cadherin-11. This suggests that cell interaction mediated by cadherin-11 induces the expression of the angiogenic factor Vegf-D in fibroblasts.
New Wearable Body Sensor for Continuous Diagnosis of Internal Tissue Bleeding (2009)

Continuous monitoring of internal bleeding in tissue is essential for assessment and treatment of medical conditions. In this study we present a new body sensor for diagnosis of internal tissue bleeding based on contact multi-frequency electromagnetic inductive measurements of the tissue. This contributes to the existing family of body network sensors. This sensor can be used in emergency medicine in the field, in a hospital, or during daily life for patients at risk of bleeding. Unlike other sensors that detect bleeding, this sensor is portable, low cost, non-invasive and does not require galvanic coupling between the electrode and the tissue under measurement. Our study includes description of the new body sensor, criteria for data processing, basic diagnostic algorithms and calibration techniques. We show feasibility of this new sensor with a sensor prototype and diagnosis of an experimental simulation of internal bleeding and hypoperfusion conditions in the brain.
A class of codes for a T active users out of N multiple-access communication system (1990)

A code construction for a T active users out of N multiple-access system (TANMAS) is discussed. The multiple-access channel (MAC) that is used in the TANMAS is a discrete-time noiseless real adder channel used without feedback with N real or binary inputs. Each input may be affected by an unknown, slowly varying channel gain and by an unknown, slowly varying channel offset. A set of N codes is constructed such that the sum of codewords of any known set of T or less active users is uniquely decodable. The sum rate of the codes approaches one from above if the input alphabet of the MAC is binary, and it approaches one from below if the input symbols are real numbers. For the case when the set of active users is unknown. For the case when the set of active users is unknown, it is shown that this set can be identified uniquely (in addition to unique decodability) provided that at most T/2 users are active simultaneously. The sum rate is then reduced to 1/2, which is approached from above and from below, respectively, for binary and for real channel inputs. A simple decoding algorithm which operates over the reals is given for the case when the set of active users is known. It is pointed out that one of the applications of the given codes is in hybrid multiple-access systems that use both multiple-access coding and collision resolution.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Activated carbonates: enabling the synthesis of differentiated polycarbonate resins via melt transcarbonation (2016)

Higher reactivity of activated carbonate (BMSC) enabling polycarbonates based on monomers that are unsuitable for traditional melt polymerization which uses diphenol carbonate (DPC), as demonstrated in the conversion plot.
Extracting Named Entities and Synonyms from Wikipedia for use in News Search (2008)

In news articles the focus on named entities is quite common and usually a news case is tied around a person, a company, or similar. One challenge from an information retrieval point of view is that one entity often have more than one way of referring to it. This means that when users use news search engines they have to use the exact same name for the entity as the articles they are interested in use. Therefore the usage of synonyms to refer to the same entity forms the basis of this thesis. We explore the idea of using Wikipedia as a data source for building a large dictionary of named entities and their synonyms. An entity dictionary like that would be very interesting because it make it possible to link synonyms to the same entity. The evaluation shows that Wikipedia is well suited as a source of named entities and synonyms as the semi-structure aids in recognizing the entities and related synonyms. The use of the dictionary in a modified search solution shows on the other hand mixed results. On problem with evaluating a solution like this is that the precision of the different synonyms is usually very high for popular entities, and when we combine different synonyms in the same query we end up giving more weight to the results that use multiple synonyms.
Microwave plasma reactions of solid monomers with silicone elastomer surfaces: a spectroscopic study (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMicrowave plasma reactions of solid monomers with silicone elastomer surfaces: a spectroscopic studyScott R. Gaboury and Marek W. UrbanCite this: Langmuir 1993, 9, 11, 3225–3233Publication Date (Print):November 1, 1993Publication History Published online1 May 2002Published inissue 1 November 1993https://pubs.acs.org/doi/10.1021/la00035a076https://doi.org/10.1021/la00035a076research-articleACS PublicationsRequest reuse permissionsArticle Views323Altmetric-Citations36LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Molecular cloning and characterization of a cDNA encoding the gibberellin biosynthetic enzyme <i>ent</i>‐kaurene synthase B from pumpkin (<i>Cucurbita maxima</i> L.) (1996)

The first committed step in the formation of diterpenoids leading to gibberellin (GA) biosynthesis is the conversion of geranylgeranyl diphosphate (GGDP) to ent-kaurene. ent-Kaurene synthase A (KSA) catalyzes the conversion of GGDP to copalyl diphosphate (CDP), which is subsequently converted to ent-kaurene by ent-kaurene synthase B (KSB). A full-length KSB cDNA was isolated from developing cotyledons in immature seeds of pumpkin (Cucurbita maxima L.). Degenerate oligonucleotide primers were designed from the amino acid sequences obtained from the purified protein to amplify a cDNA fragment, which was used for library screening. The isolated full-length cDNA was expressed in Escherichia coli as a fusion protein, which demonstrated the KSB activity to cyclize [3H]CDP to [3H]ent-kaurene. The KSB transcript was most abundant in growing tissues, but was detected in every organ in pumpkin seedlings. The deduced amino acid sequence shares significant homology with other terpene cyclases, including the conserved DDXXD motif, a putative divalent metal ion-diphosphate complex binding site. A putative transit peptide sequence that may target the translated product into the plastids is present in the N-terminal region.
Methyl jasmonate upregulates biosynthetic gene expression, oxidation and conjugation of polyamines, and inhibits shoot formation in tobacco thin layers (2001)

The effect of methyl jasmonate (MJ) on de novo shoot formation and polyamine metabolism was investigated in thin layer explants of tobacco (Nicotiana tabacum L. cv. Samsun). A relatively low concentration of MJ (0.1 microM) enhanced explant fresh weight, but had no effect on the final number of shoots per explant while higher concentrations (1 and 10 microM) significantly inhibited organogenesis. The histological study revealed that, with increasing concentrations of MJ, the formation of meristemoids and shoot domes declined and the incidence of cell hypertrophy increased. In explants cultured with 0.1, 1 or 10 microM MJ, the endogenous levels of free putrescine, spermidine and spermine generally declined compared with controls, after 7 and 15 d. Perchloric acid-soluble conjugated polyamines accumulated dramatically during culture, but much more so in the presence of MJ than in controls. Acid-insoluble conjugated spermidine alone increased in response to the elicitor. Activities of the putrescine biosynthetic enzymes arginine decarboxylase (ADC, EC 4.1.1.19) and ornithine decarboxylase (ODC, EC 4.1.1.17) in the soluble fraction of MJ-treated explants displayed up to 3-fold increases relative to control explants. However, the most relevant increases in these enzyme activities occurred in the particulate fraction. The activity of S:-adenosylmethionine decarboxylase (SAMDC, EC 4.1.1.21), an enzyme involved in spermidine and spermine biosynthesis, was also stimulated by exposure to MJ. Northern analyses revealed MJ-induced, generally dose-dependent, increases in the mRNA levels of all three enzymes. Diamine oxidase (DAO, EC 1.4.3.6) activity was stimulated by MJ mainly in the cell wall fraction. The upregulation of polyamine metabolism is discussed in relation to the morphogenic behaviour of MJ-treated explants.
Performance of calibration standards for antigen quantitation with flow cytometry (1998)

In the frame of the activities initiated by the Task Force for Antigen Quantitation of the European Working Group on Clinical Cell Analysis (EWGCCA), an experiment was conducted to evaluate microbead standards used for quantitative flow cytometry (QFCM). An unified window of analysis (UWA) was established on three different instruments (EPICS XL [Coulter Corporation, Miami, FL], FACScan and FACS Calibur [Becton Dickinson, San Jose, CA]) with QC3 microbeads (FCSC, PR). By using this defined fluorescence intensity scale, the performance of several monoclonal antibodies directed to CD3, CD4, and CD8 (conjugated and unconjugated), from three manufacturers (BDIS, Coulter [Immunotech], and DAKO) was tested. In addition, the QIFI system (DAKO) and QuantiBRITE (BDIS), and a method of relative fluorescence intensity (RFI, method of Giorgi), were compared. mAbs reacting with three more antigens, CD16, CD19, and CD38 were tested on the FACScan instrument. Quantitation was carried out using a single batch of cryopreserved peripheral blood leukocytes, and all tests were performed as single color analyses. Significant correlations were observed between the antibody-binding capacity (ABC) values of the same CD antigen measured with various calibrators and with antibodies differing in respect to vendor, labeling and possible epitope recognition. Despite the significant correlations, the ABC values of most monoclonal antibodies differed by 20-40% when determined by the different fluorochrome conjugates and different calibrators. The results of this study indicate that, at the present stage of QFCM consistent ABC values may be attained between laboratories provided that a specific calibration system is used including specific calibrators, reagents, and protocols.
Adjoint-Based Well-Placement Optimization Under Production Constraints (2007)

Abstract Determining the optimal location of wells with the aid of an automated search algorithm can significantly increase a project's Net Present Value (NPV) as modeled in a reservoir simulator. This paper has two main contributions: first to determine the effect of production constraints on optimal well locations, and second to determine optimal well locations using a gradient-based optimization method. Our approach is based on the concept of surrounding the wells whose locations have to be optimized by so-called pseudo-wells. These pseudo-wells produce or inject at a very low rate, and thus have a negligible influence on the overall flow throughout the reservoir. The gradients of NPV over the lifespan of the reservoir with respect to flow rates in pseudo-wells are computed using an adjoint model. These are subsequently used to approximate ‘improving directions’, i.e. directions in which to move the wells to achieve an increased NPV, based on which improving well positions can be determined. The main advantage over previous approaches, such as finite difference or stochastic perturbation methods, is that the method computes improving directions for all wells in only one forward and one backward (adjoint) simulation. The process is repeated until no further improvements are obtained. The method is illustrated by two waterflooding examples. In the first the location of a single injector is optimized to maximize NPV. Starting from four different initial injector locations the algorithm converges to four similar local optima. The second example involves optimization of the locations of 9 producers and 4 injectors. Starting from two different initial well configurations we obtain nearly the same (local) optimum.
An LSI adaptive array processor (1983)

Describes an LSI adaptive array processor (AAP) for two-dimensional data processings. The AAP contains a large number of one-bit processing elements (PEs) arranged in a square array. The large degree of parallelism and control registers in each PE allow for high speed and flexible operations. High transfer capability is also obtained by a simple inter-PE connection network with hierarchical bypasses. The high applicability to various data processings is indicated by a matrix multiplication example, utilizing an algorithm similar to a systolic one. An AAP LSI composed of 8/spl times/8 PEs with powerful functions has been implemented in a 96.0 mm/SUP 2/ chip by using 2 /spl mu/m Si-gate p-well CMOS technology. A high-speed cycle time of 55 ns, low power dissipation of 1.1 W, and high packing density of 1170 transistors/mm/SUP 2/ has been achieved by a skilful manual design. Though the LSI contains as many as 111900 transistors, the design effort has only required one man-year due to cellular array regularity. This LSI is expected to realize a high-performance AAP compactly.
SimGNN: A Neural Network Approach to Fast Graph Similarity Computation (2018)

Graph similarity search is among the most important graph-based applications, e.g. finding the chemical compounds that are most similar to a query compound. Graph similarity computation, such as Graph Edit Distance (GED) and Maximum Common Subgraph (MCS), is the core operation of graph similarity search and many other applications, but very costly to compute in practice. Inspired by the recent success of neural network approaches to several graph applications, such as node or graph classification, we propose a novel neural network based approach to address this classic yet challenging graph problem, aiming to alleviate the computational burden while preserving a good performance. The proposed approach, called SimGNN, combines two strategies. First, we design a learnable embedding function that maps every graph into a vector, which provides a global summary of a graph. A novel attention mechanism is proposed to emphasize the important nodes with respect to a specific similarity metric. Second, we design a pairwise node comparison method to supplement the graph-level embeddings with fine-grained node-level information. Our model achieves better generalization on unseen graphs, and in the worst case runs in quadratic time with respect to the number of nodes in two graphs. Taking GED computation as an example, experimental results on three real graph datasets demonstrate the effectiveness and efficiency of our approach. Specifically, our model achieves smaller error rate and great time reduction compared against a series of baselines, including several approximation algorithms on GED computation, and many existing graph neural network based models. To the best of our knowledge, we are among the first to adopt neural networks to explicitly model the similarity between two graphs, and provide a new direction for future research on graph similarity computation and graph similarity search.