Graft-versus-Host Disease and Liver Transplantation (1992)

Letters15 July 1992Graft-versus-Host Disease and Liver TransplantationAlex M. DePaoli, MD, Jacob Bitran, MDAlex M. DePaoli, MD, Jacob Bitran, MDAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-117-2-170_1 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the Editors: We offer another case in support of the supposition by Collins and colleagues (1) that graft-versus-host disease (GVHD) in liver transplantation is more common than previously thought.An 18-year-old white woman (A-positive) received an ABO-mismatched orthotopic liver transplant from a previously healthy man (O-positive) for cryptogenic cirrhosis after her first transplant failed secondary to biliary obstruction. The procedure was uncomplicated. Her hemoglobin fell rapidly from 10.2 mg/dL to 6.6 mg/dL between days 5 and 9 after surgery without evidence of bleeding. High titers of anti-A antibodies were found in the patient's serum, believed to be the result...References1. CollinsCooperNikaeinKlintmalmFay RCAGJ. Graft versus host disease in a liver transplant recipient. Ann Intern Med. 1992; 116:391-2. LinkGoogle Scholar2. RamseyNusbacherStarzlLindsay GJTG. Isohemagglutinins of graft origin after ABO-unmatched liver transplantation. N Engl J Med. 1984;311:1167-70. CrossrefMedlineGoogle Scholar3. RobertsAscherLakeCapperPurohitGarovoy JNJJSM. Graft vs. host disease after liver transplantation in humans: a report of four cases. Hepatology. 1991;14:274-81. CrossrefMedlineGoogle Scholar4. Von FliednerHigbyKim VDU. Graft-versus-host reaction following blood product transfusion. Am J Med. 1982;72:951-61. CrossrefMedlineGoogle Scholar1. Sachs D. Specific transplantation tolerance. N Engl J Med. 1992; 325:1240-2. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Lutheran General Hospital Park Ridge, IL 60068 PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byPost-liver transplantation GVHD: time to consider histocompatibility testingImproved survival after LTx-associated acute GVHD with mAb therapy targeting IL2RAb and soluble TNFAb: Single-center experience and systematic reviewGraft Versus Host Disease After Liver Transplantation in AdultsAbsence of peripheral blood chimerism in graft-vs-host disease following orthotopic liver transplantation: case report and review of the literatureGraft-Versus-Host Disease After Intestinal and Multivisceral TransplantationGraft versus host disease after liver transplantation – a single center experience and review of literatureGraft vs. host disease after liver transplantation: A new approach is neededRecipient and donor factors influence the incidence of graft-vs.-host disease in liver transplant patientsGraft-vs.-host disease in lung and other solid organ transplant recipientsAcute Graft versus Host Disease After Liver Transplantation: Patterns of Lymphocyte ChimerismRash and pancytopenia as initial manifestations of acute graft-versus-host disease after liver transplantationAcute Graft Versus Host Disease Following Liver Transplantation: The Enemy WithinLiver transplant-associated graft-versus-host diseaseMicrochimerism, GVHD, and tolerance in solid organ transplantationHUMAN HERPESVIRUS-6 IN LIVER TRANSPLANT RECIPIENTSRapid method for the analysis of peripheral chimerism in suspected graft-versus-host disease after liver transplantationCutaneous lesions as the presenting sign of acute graft-versus-host disease following liver transplantationB-CELL-MEDIATED GRAFT-VERSUS-HOST DISEASE IN TRANSPLANTATIONDonor-Derived Long-Term Multilineage Hematopoiesis in a Liver-Transplant Recipient 15 July 1992Volume 117, Issue 2Page: 170-171KeywordsAntibodiesCirrhosisGraft vs host diseaseHemoglobinHemorrhageLiver diseasesLiver transplantationOrthotopic liver transplantationSurgery Issue Published: 15 July 1992 PDF downloadLoading ...