gebhart/patrepeval huggingface dataset:
Unified Inverse Depth Parametrization for Monocular SLAM (2006)

Recent work has shown that the probabilistic SLAM approach of explicit uncertainty propagation can succeed in permitting repeatable 3D real-time localization and mapping even in the 'pure vision' domain of a single agile camera with no extra sensing. An issue which has caused difficulty in monocular SLAM however is the initialization of features, since information from multiple images acquired during motion must be combined to achieve accurate depth estimates. This has led algorithms to deviate from the desirable Gaussian uncertainty representation of the EKF and related probabilistic filters during special initialization steps.
Review of horizontal drilling technology for methane drainage from U.S. coalbeds (1980)

Field demonstrations conducted by the Bureau of Mines showed that horizontal boreholes drilled into coal beds can effectively intercept methane flow while forcing the water out of the hole, making the gas relatively easy to recover via inexpensive gas-water separators. A review of the commercially available equipment for drilling from underground locations discusses the drainage and control technologies and the ongoing demonstration projects at various mining sites. As deeper coal beds are mined, methane drainage will become a necessity rather than an option. Carefully planning the degasification step before the mine is opened can result in a safer work environment and - by reducing ventilation costs and increasing production - a more profitable operation.
Functional compartmentalization of the nucleus (1996)

Recent applications of cell biology and molecular genetics have built an image of nuclear organization in which the molecular machines involved in transcription, RNA processing and replication assemble morphologically distinct nuclear organelles with defined functional properties. These observations indicate a very high level of structural organization for the various metabolic activities occurring within the nucleus. We discuss the possible existence of novel regulatory functions inherent to nuclear architecture itself.
A Bacterial Artificial Chromosome Library for Sequencing the Complete Human Genome (2001)

A 30-fold redundant human bacterial artificial chromosome (BAC) library with a large average insert size (178 kb) has been constructed to provide the intermediate substrate for the international genome sequencing effort. The DNA was obtained from a single anonymous volunteer, whose identity was protected through a double-blind donor selection protocol. DNA fragments were generated by partial digestion with EcoRI (library segments 1--4: 24-fold) and MboI (segment 5: sixfold) and cloned into the pBACe3.6 and pTARBAC1 vectors, respectively. The quality of the library was assessed by extensive analysis of 169 clones for rearrangements and artifacts. Eighteen BACs (11%) revealed minor insert rearrangements, and none was chimeric. This BAC library, designated as "RPCI-11," has been used widely as the central resource for insert-end sequencing, clone fingerprinting, high-throughput sequence analysis and as a source of mapped clones for diagnostic and functional studies.
Insulin-like growth factor I increases bone formation in old or corticosteroid treated rats (1997)

We studied bone induction in subcutaneous implants of demineralized bone matrix with or without insulin-like growth factor I (IGF-I) in aged or corticosteroid-treated rats. Each rat carried one pair of implants, one control and one experiment implant, containing IGF-I dissolved in a hyaluronan solution for slow release. The rats were killed after 3 weeks and the results were evaluated by measuring the calcium content of implants. Young (6-7 weeks) and old (19-27 months) rats were used. A group of young rats was treated for 1 week with subcutaneous injections of 140 micrograms/kg dexamethasone daily. Old rats produced only approximately 1% as much bone as young rats. Local delivery of IGF-I did not increase bone formation in young rats. In old rats, bone formation was increased by IGF-I, 3000 ng/implant. Corticosteroids reduced bone formation in young rats. This effect was partially reversed by local administration of IGF-I.
Interleukin-6 Promoter Genotype and Restenosis after Femoropopliteal Balloon Angioplasty: Initial Observations (2004)

The IL-6 promoter polymorphism (-174)G/C seems to influence the occurrence of restenosis after PTA. Homozygous carriers of the (-174)C allele have an increased rate of intermediate-term restenosis.
Self-Assembled Molecular Films of Aminosilanes and Their Immobilization Capacities (2004)

The assembly of two aminosilanes on silicon dioxide surfaces is investigated in this work. It is found that for 3-aminopropyltrimethoxysilane (APS), a smaller concentration of the silane and trace amounts of water in the deposition medium, an optimum time, and a postdeposition thermal curing are necessary to obtain a high primary-amine content. By optimization of deposition conditions, uniform APS films with a primary-amine content of 88.6% were obtained. The dependence of the primary-amine content on the experimental parameters is related to the extent to which amines are lost to hydrogen bonding with each other or with the substrate surface. Whenp-aminophenyltrimethoxysilane (APhS) was used, the primary-amine content in the film reached 100% and the surface morphology was more uniform than that of APS films under the same conditions. This is attributed to the rigid phenyl component in APhS that reduces opportunities for hydrogen bonding. In a comparison of the immobilization capacities of the different aminosilane substrates for pyromellitic dianhydride (PMDA), it is observed that higher primary-amine content favors higher uptake, and the APhS film yields 100% PMDA coverage. We infer that primary-amine content could be a measure of the film morphology and accessibility of the substrate amine groups.
Studies on the Th-cell Subsets From Peripheral Blood of the Patients with Different Courses of Condyloma Acuminatum (2003)

Objective 


Methods 


Results 


Conclusion 
>To investigate the status of cellular immunity from Th cell polarization in patients with different courses of condyloma acuminatum(CA).Methods The isolated PBMC were polarized by PHA and self-plasma for 72 hours,then followed by two-color immunofluorescent staining with anti-CD4-PE and anti-CCR5-FITC,or with anti-CD4-FITC and anti-CCR3-PE.Finally the stained cells were analyzed by flow-cytometry.Results The percentages of Th1/Th2 cells of the short-course group and long-course group were(25.82±2.22)%/(14.80±1.14)% and(12.20±1.37)%/(13.74±0.99)%,respectively;the differences between normal control and two CA groups were significant(P<0.05).The Th1/Th2 cells ratios of short-course and long-course group were1.75±0.17 or 0.89±0.11,respectively.Conclusions It seems that there was Th1 predominant response in CA patients with short-course and Th2 predominant response in long-course group.These data indicate that there may be an possible switch f


Key words: 
Condylomata acuminata; CD4-positive T-lymphocytes
Gas chromatographic‐mass spectrometric metabolic profiling of patients with fatal infantile mitochondrial myopathy with de Toni‐Fanconi‐Debré syndrome (1996)

The metabolic profiles of three patients with fatal infantile mitochondrial myopathy with de Toni-Fanconi-Debré syndrome were studied by simultaneous analysis, after urease treatment of urinary organic acids, carbohydrates, polyols and amino acids using gas chromatography/mass spectrometry (GC/MS). All three patients persistently showed lactic aciduria, phosphaturia, glucosuria and generalized amino aciduria. This abnormal urinary metabolic profile was observed before the onset of any clinical symptoms, indicating that chemical diagnosis may be done presymptomatically. In one patient, the concentration of lactate increased in parallel with the severity of the clinical condition, whereas the urinary levels of 3-hydroxybutyrate, amino acids and glucose fluctuated and showed only a general tendency to increase with the clinical course. The above results suggest that simultaneous GC/MS analyses, without fractionation, of urinary metabolites facilitate not only the early chemical diagnosis either before or after the first onset, but also follow-up studies, providing an important index for the evaluation of the severity and clinical course in patients with this disorder.
Antithrombotic effect of a monoclonal antibody against tissue factor in a rabbit model of platelet-mediated arterial thrombosis. (1992)

Activation of the coagulation system by contact of circulating blood with tissue factor, a component of the extrinsic blood coagulation pathway that is produced in the vessel wall, may represent a pathway for the initiation of thrombosis in atherosclerotic vessels. This hypothesis was tested in vivo in a rabbit femoral artery eversion (inside-out) graft model, in which the adventitia, with its tissue factor, was exposed to circulating blood. Intra-arterial infusion of a neutralizing monoclonal antibody against tissue factor (D3) at a rate of 12 mg/kg over 15 minutes prevented thrombosis of a 7-8-mm eversion graft within a 2-hour observation period in four of five rabbits, whereas with a control antibody infusion (MA-15C5), occlusion occurred within 2 hours in five of six rabbits. In vitro immersion before reinsertion of the arterial segment in a solution containing 2 mg/ml of the control antibody for 30 minutes was associated with occlusion in all six rabbits, whereas pretreatment with D3 was associated with persistent patency in three of nine rabbits. Stepwise logistic-regression analysis of the results with perfusion status as the dependent variable and type of antibody (D3 or MA-15C5), application method (infusion versus immersion), and graft segment length as independent variables yielded a significant difference in frequency of occlusion with the two antibodies (p = 0.016). It is concluded that exposure of tissue factor to flowing blood may constitute a trigger mechanism for platelet-mediated arterial thrombosis.
A new intra prediction method using channel correlations for the H.264/AVC intra coding (2009)

This paper introduces a new intra prediction algorithm that exploits the correlations between the color channels, for the H.264/AVC intra coding. The main idea is to use the weighted sum of neighboring pixels as a new chroma prediction tool, where the weighting coefficients are determined considering the inter-channel correlations. Specifically the weighting coefficients are determined under the assumption that the similarity of a chrominance channel intensity increases as the distance of the luminance channel intensity decreases. The proposed method is added to the conventional chroma prediction modes with a little modification in the chroma prediction mode binarization. The experiments show that the proposed method provides up to 1.0 dB gain for the color-abundant images.
Differential effect of ultracentrifugation on apolipoprotein A-I-containing lipoprotein subpopulations. (1988)

Two populations of apolipoprotein (apo) A-I-containing lipoprotein particles are found in high density lipoproteins (HDL): those that also contain apo A-II[Lp(A-I w A-II)] and those that do not [Lp(A-I w/o A-II)]. Lp(A-I w/o A-II) comprised two distinct particle sizes with mean hydrates Stokes diameter of 10.5 nm for Lp(A-I w/o A-II)1 and 8.5 nm for Lp(A-I w/o A-II)2. To study the effect of ultracentrifugation on these particles, Lp(A-I w/o A-II) and Lp(A-I w A-II) were isolated from the plasma and the ultracentrifugal HDL (d 1.063-1.21 g/ml fractions) of five normolipidemic and three hyperlipidemic subjects. The size subpopulations of these particles were studied by gradient polyacrylamide gel electrophoresis. Several consistent differences were detected between plasma Lp(A-I w/o A-II) and HDL Lp(A-I w/o A-II). First, in all subjects, the relative proportion of Lp(A-I w/o A-II)1 to Lp(A-I w/o A-II)2 isolated from HDL was reduced. Second, particles larger than Lp(A-I w/o A-II)1 and smaller than Lp(A-I w/o A-II)2 were considerably reduced in HDL. Third, a distinct population of particles with approximate Stokes diameter of 7.1 nm usually absent in plasma was detected in HDL Lp(A-I w/o A-II). Little difference in subpopulation distribution was detected between Lp(A-I w A-II) isolated from the plasma and HDL of the same subject. When plasma Lp(A-I w/o A-II) and Lp(A-I w A-II) were centrifuged, 14% and 4% of A-I were, respectively, recovered in the D greater than 1.21 g/ml fraction. Only 2% A-II was found in this density fraction. These studies show that the Lp(A-I w/o A-II) particles are less stable than Lp(A-I w A-II) particles upon ultracentrifugation. Among the various Lp(A-I w/o A-II) subpopulations, particles larger than Lp(A-I w/o A-II)1 and smaller than Lp(A-I w/o A-II)2 are most labile.
Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease (2010)

Our previous analyses showed that allopregnanolone (APalpha) significantly increased proliferation of rodent and human neural progenitor cells in vitro. In this study, we investigated the efficacy of APalpha to promote neurogenesis in the hippocampal subgranular zone (SGZ), to reverse learning and memory deficits in 3-month-old male triple transgenic mouse model of Alzheimer's (3xTgAD) and the correlation between APalpha-induced neural progenitor cell survival and memory function in 3xTgAD mice. Neural progenitor cell proliferation was determined by unbiased stereological analysis of BrdU incorporation and survival determined by FACS for BrdU+ cells. Learning and memory function was assessed using the hippocampal-dependent trace eye-blink conditioning paradigm. At 3 months, basal level of BrdU+ cells in the SGZ of 3xTgAD mice was significantly lower relative to non-Tg mice, despite the lack of evident AD pathology. APalpha significantly increased, in a dose-dependent manner, BrdU+ cells in SGZ in 3xTgAD mice and restored SGZ proliferation to normal magnitude. As with the deficit in proliferation, 3xTgAD mice exhibited deficits in learning and memory. APalpha reversed the cognitive deficits to restore learning and memory performance to the level of normal non-Tg mice. In 3xTgAD mice, APalpha-induced survival of neural progenitors was significantly correlated with APalpha-induced memory performance. These findings suggest that early neurogenic deficits, which were evident before immunodetectable Abeta, may contribute to the cognitive phenotype of AD, and that APalpha could serve as a regenerative therapeutic to prevent or delay neurogenic and cognitive deficits associated with mild cognitive impairment and Alzheimer's disease.
Photoluminescence of Cerium‐Doped α‐SiAlON Materials (2004)

Cerium‐doped α‐SiAlON (M x Si 12−( m + n ) Al m + n O n N 16– n ) materials have been prepared by gas‐pressure sintering and post‐hot‐isostatic‐press (HIP) annealing, using four powder mixtures of α‐Si 3 N 4 , AlN, and either (i) CeO 2 , (ii) CeO 2 + Y‐α‐SiAlON seed, (iii) CeO 2 + Y 2 O 3 , or (iv) CeO 2 + CaO. Cerium‐containing CeAl(Si 6– z Al z )(N 10– z O z ) (JEM) phase, rather than Ce‐α‐SiAlON phase, forms in the sample with only CeO 2 , whereas a single‐phase α‐SiAlON generates in samples with dual doping (CeO 2 + Y 2 O 3 and CeO 2 + CaO). On ultraviolet‐light excitation, JEM gives one broad emission band with maximum at 465 nm and a shoulder at 498 nm; α‐SiAlON shows an intense and broad emission band that peaks at 500 nm. The unusual long‐wavelength emissions in JEM and α‐SiAlON are due to increases in the nephelauxetic effect and the ligand‐field splitting of the 5 d band, because the coordination of Ce 3+ in JEM and α‐SiAlON is nitrogen enriched.
Structural Biology and Evolution of the TGF-β Family (2016)

We review the evolution and structure of members of the transforming growth factor β (TGF-β) family, antagonistic or agonistic modulators, and receptors that regulate TGF-β signaling in extracellular environments. The growth factor (GF) domain common to all family members and many of their antagonists evolved from a common cystine knot growth factor (CKGF) domain. The CKGF superfamily comprises six distinct families in primitive metazoans, including the TGF-β and Dan families. Compared with Wnt/Frizzled and Notch/Delta families that also specify body axes, cell fate, tissues, and other families that contain CKGF domains that evolved in parallel, the TGF-β family was the most fruitful in evolution. Complexes between the prodomains and GFs of the TGF-β family suggest a new paradigm for regulating GF release by conversion from closed- to open-arm procomplex conformations. Ternary complexes of the final step in extracellular signaling show how TGF-β GF dimers bind type I and type II receptors on the cell surface, and enable understanding of much of the specificity and promiscuity in extracellular signaling. However, structures suggest that when GFs bind repulsive guidance molecule (RGM) family coreceptors, type I receptors do not bind until reaching an intracellular, membrane-enveloped compartment, blurring the line between extra- and intracellular signaling. Modulator protein structures show how structurally diverse antagonists including follistatins, noggin, and members of the chordin family bind GFs to regulate signaling; complexes with the Dan family remain elusive. Much work is needed to understand how these molecular components assemble to form signaling hubs in extracellular environments in vivo.
Epstein-Barr virus-coded BHRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell death. (1993)

Epstein-Barr virus, a human herpesvirus that persists within the B-lymphoid system, can enhance the survival potential of latently infected B cells in vitro through up-regulation of the cellular survival protein Bcl-2. The possibility that an analogous effect is operative in lytically infected cells was suggested by the observation of distant sequence homology between an Epstein-Barr virus-coded early lytic cycle protein, BHRF1, and Bcl-2. Here we show by gene transfer that BHRF1 resembles Bcl-2 both in its subcellular localization and in its capacity to enhance B-cell survival. Thus confocal microscopic analysis of cells acutely cotransfected with BHRF1 and Bcl-2 expression vectors revealed substantial colocalization of the two proteins in the cytoplasm. In subsequent experiments, stable BHRF1 gene transfectants of Burkitt lymphoma cells paralleled Bcl-2 transfectants in their enhanced survival under conditions that induce cell death by apoptosis. Despite their limited sequence conservation, therefore, the two proteins appear to be functionally homologous. We suggest that BHRF1 provides an alternative, Bcl-2-independent, means of enhancing B-cell survival that may operate during the virus lytic cycle.
Functional gene cassettes in development. (1993)

Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans the biological, physical, and social sciences.
Imaging gold nanorods in excised human breast carcinoma by spectroscopic optical coherence tomography (2009)

Plasmon-resonant gold nanorods (GNRs) can serve as imaging agents for spectroscopic optical coherence tomography (SOCT). The aspect ratio of the GNRs are adjusted for maximum absorption in the far red to create a partial spectral overlap with the low-wavelength edge of the near-infrared SOCT imaging band. The spectroscopic absorption profile of the GNRs is incorporated into a depth-resolved algorithm for mapping the relative GNR density within OCT images. This technique enables us to image GNR distributions in excised human breast carcinomas, demonstrating their potential as OCT contrast agents in heteregeneous, highly scattering tissues.
MIRADAS SUBVERSIVAS REÚNE AFICIONES, VIVENCIAS Y REFLEXIONES CRÍTICAS DE SERGIO FERNÁNDEZ (1997)

SERGIO FERNANDEZ, AUTOR DEL LIBRO MIRADAS SUBVERSIVAS, EDITADO POR EL CONSEJO NACIONAL PARA LA CULTURA Y LAS ARTES, DIJO QUE ES UN TEXTO EN PARTE DE VIAJES, EN PARTE DE CHISMES Y EN PARTE DE CURIOSIDADES. TAMBIEN ES UN LIBRO DE ARTE EN DONDE SE INTERCALAN RECADOS, CARTAS Y CONVERSACIONES, Y EN DONDE EL INTERES FUNDAMENTAL ES LA PLASTICA. EN MIRADAS SUBVERSIVAS, SERGIO FERNANDEZ UBICA A LOS ARTISTAS DEL RENACIMIENTO COMO LOS GRANDES RENOVADORES DEL MUNDO Y DE LA CARNE, Y DEL GOZO DE LOS SENTIDOS. ADEMAS, RELATA EXPERIENCIAS PORNOGRAFICAS PARA VER HASTA QUE PUNTO PUEDE CONVERTIRSE ESTO EN LITERATURA. AL COMENTAR LA OBRA, PRESENTADA EN LA FACULTAD DE FILOSOFIA Y LETRAS, MIGUEL ANGEL QUEMAIN, DIRECTOR DE LA REVISTA MEXICANA DE CULTURA, SUPLEMENTO DOMINICAL DEL PERIODICO EL NACIONAL, APUNTO QUE EL LIBRO CONTIENE DIVERSIDAD DE GENEROS, TODOS EN TRANCE, A PUNTO DE PRESENTARSE INTEGRAMENTE Y A PUNTO DE INSINUARSE. UNO DE ELLOS ES LA NOVELA.
Stable Operation of Femtosecond Laser Frequency Combs with Uncertainty at the 10-17 Level toward Optical Frequency Standards (2009)

We have developed two femtosecond laser frequency combs (FLFCs) employing different designs and no external spectral broadening devices. The FLFCs referenced to a microwave standard were directly compared and confirmed to have a relative fractional uncertainty of 8.1 ×10-17 mainly due to imperfection in our comparison technique. They have also achieved uninterrupted daily operation typically more than 8 hours. They are found to be suitable for the optical standards from the absolute frequency measurement for a clock transition of 40Ca+ ions, that was recently performed in National Institute of Information and Communications Technology.
Synthesis of alkylsalicylic acids as antimicrobial agents (1971)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of alkylsalicylic acids as antimicrobial agentsD. Buckley and John ThomasCite this: J. Med. Chem. 1971, 14, 3, 265Publication Date (Print):March 1, 1971Publication History Published online1 May 2002Published inissue 1 March 1971https://pubs.acs.org/doi/10.1021/jm00285a031https://doi.org/10.1021/jm00285a031research-articleACS PublicationsRequest reuse permissionsArticle Views197Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts