gebhart/patrepeval huggingface dataset:
A study of an evaluation methodology for unbuffered multistage interconnection networks (2004)

Interconnection network performance is a key factor when constructing parallel computers. The choice of an interconnection network used in a parallel computer depends on a large number of performance factors which are very often application dependent. We give the outline of a performance evaluation and comparison methodology using what we think of as the most important parameters to be considered when solving such a problem. This methodology is applied on a new interconnection network called MCRB network and on Omega network.
Metastable nanosized aluminum powder as a reactant in energetic formulations (1998)

Aluminum powder is an important ingredient in many propellant, explosives and pyrotechnic applications. The production of nanosized aluminum powder by the electroexplosion of metal wire has been practices in the former USSR since the mid 1970`s. Differential scanning calorimetry, differential thermal analysis and x-ray phase analysis was performed on aluminum powder both before and after air passivation, as well as aluminum that was protected under kerosene, pentane, toluene and hexane. Earlier Soviet reports of unexplained thermal releases and metastable behavior have been investigated. Anomalous behavior previously reported included phase transformations at temperatures far below melting with the release of heat and chemoluminescence and self sintering of particles with a heat release large enough to melt the powders.
Atomic force microscopy of conventional and unconventional nucleic acid structures (1992)

Images of conventional (Watson-Crick base paired) and unconventional (G4 RNA) nucleic acid structures have been obtained by atomic force microscopy. The images are reproducibly generated from samples deposited on freshly cleaved mica. Periodic substructural features are evident in fibres observed in both cases. In the case of G4 RNA, tip-induced formation of large fibres is observed.
Ultrafast impulsive excitation of coherent longitudinal acoustic phonon oscillations in highly photoexcited InSb (2001)

We report on the direct time-resolved measurement of high-frequency coherent longitudinal acoustic (LA) phonon oscillations in InSb. Two LA-phonon modes are impulsively generated in a highly photoexcited InSb sample and detected through reflectivity modulation with a temporal resolution of 15 fs. The measured frequencies, νLA(L1)=4.34 THz and νLA(X3)=3.75 THz, are in excellent agreement with those obtained through time-independent techniques. A frequency redshift in the LA(L1)-phonon frequency, as the energy fluence is increased beyond 10% of the damage threshold fluence, is attributed to an anisotropic impulsive softening of the InSb lattice.
Insect Antifeedant Activity of Flavones and Chromones against Spodoptera litura (2002)

The antifeedant polymethylated flavones 5-hydroxy-3,6,7,8,4'-heptamethoxyflavone, 5-hydroxy-3,6,7,8-tetramethoxyflavone, and 5,6-dihydroxy-3,7-dimethoxyflavone have been isolated from the cudweed, Gnaphalium affine D. Don (Compositae). These flavonoids and authentic analogues showed insect antifeedant activity against the common cutworm (Spodoptera litura F.). In a previous paper, it was suggested that there was no substituent on the B-ring of the flavonoid for the beneficial antifeedant activity against the common cutworm. These flavonoids having a phenyl group as the B-ring and the chromone as elimination of the B-ring from the flavonoids were used to test the hypothesis of the previously described B-ring effect. The known fact is that Sculletaria baicarensis (Rutaceae) produced the 2-phenyl flavone. Test compounds and their methylated derivatives were prepared from this material for the structure-activity relationship (SAR) study of insect antifeedant activity. In spite of the 2-phenyl flavonoids, some tested compounds did not show any insect antifeedant activity against the common cutworm, although these inactive flavonoids were deficient in the 6-substituent group on the A-ring of the flavonoid. This 6-position-substituted derivative almost showed strong insect antifeedant activity against common cutworm. Moreover, the tested flavonoids having a hydroxyl group as a substituent on any of the positions tended to increase the activity. These results suggested the importance of the 6-position substitution on the flavonoid; however, hydrophilic substituents decreased the activity. Baicalein (5,6,7-trihydroxyflavone) derivatives did not show any activity despite having the 6-substituent derivative. Although the activity of some chromones increased the activity of the flavone, the bulky B-ring was a disadvantage for the antifeedant activity. It was suggested that the charge on C(3) and C(5) of the flavonoid was important for the biological activity. Additionally, an adequate hydrogen bonding property, which is different from lipophilicity, was an advantage for the activity on the basis of a QSAR analysis.
The Commonality of Risk Factors for Nosocomial Colonization and Infection with Antimicrobial-Resistant Staphylococcus aureus, Enterococcus, Gram-Negative Bacilli, Clostridium difficile, and Candida (2002)

Recent years have witnessed a rapidly growing crisis in antimicrobial resistance, especially among microorganisms that cause nosocomial infection. To better understand common risk factors among multiresistant organisms, this review explores risk factors for nosocomial infection with methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococcus, Clostridium difficile, extended-spectrum beta-lactamase-producing gram-negative bacilli, and Candida. This review comprises data from 74 published studies; 53 (71%) were retrospective studies and addressed few risk factors or did not quantify risk. The analysis shows impressive commonality of risk factors across these diverse multiresistant organisms: advanced age; underlying diseases and severity of illness; inter-institutional transfer of the patient, especially from a nursing home; prolonged hospitalization; gastrointestinal surgery or transplantation; exposure to invasive devices of all types, especially central venous catheters; and exposure to antimicrobial drugs, especially cephalosporins. More restricted use of antibiotics, especially cephalosporins, and strategies to prevent medical device-related infection and cross-infection in the hospital would yield benefit with all types of resistant organisms. Preemptive isolation of all patients with risk factors for infection by resistant organisms would very likely reduce secondary spread within the hospital. Conversely, programs that focus on only one organism or one antimicrobial drug are unlikely to succeed. Prospective studies of sufficient size that address all potential risk factors, especially individual anti-infective agents, and that use matched controls who are shown by surveillance cultures to be free of colonization by resistant organisms would enhance understanding of the epidemiology of antimicrobial resistance in institutions and guide efforts to develop more effective strategies for prevention.
The elastase-mediated pathway of fibrinolysis (1990)

Plasmin and elastase degrade fibrin and inhibit the blood coagulation system by degrading key proteins. Elastase can facilitate plasmin expression via an alternative pathway of plasminogen activation. Elastase modifies plasminogen to yield a zymogen that is a better substrate for activators than native plasminogen. Furthermore, elastase inactivates the inhibitor system of plasmin and plasminogen activators without affecting plasmin and plasminogen activators. While plasmin activity develops from a blood zymogen as a consequence of activators synthesized and secreted by endothelium and possibly other cells, elastase is secreted in an active form primarily by polymorphonuclear leukocytes. Plasmin and elastase may play mutual roles in thrombolysis, inflammation, and tumour invasion and metastasis.
Current-voltage characteristics of high current density silicon Esaki diodes grown by molecular beam epitaxy and the influence of thermal annealing (2000)

We present the characteristics of uniformly doped silicon Esaki tunnel diodes grown by low temperature molecular beam epitaxy (T/sub growth/=275/spl deg/C) using in situ boron and phosphorus doping. The effects of ex situ thermal annealing are presented for temperatures between 640 and 800/spl deg/C. A maximum peak to valley current ratio (PVCR) of 1.47 was obtained at the optimum annealing temperature of 680/spl deg/C for 1 min. Peak and valley (excess) currents decreased more than two orders of magnitude as annealing temperatures and times were increased with rates empirically determined to have thermal activation energies of 2.2 and 2.4 eV respectively. The decrease in current density is attributed to widening of the tunneling barrier due to the diffusion of phosphorus and boron. A peak current density of 47 kA/cm/sup 2/ (PVCR=1.3) was achieved and is the highest reported current density for a Si-based Esaki diode (grown by either epitaxy or by alloying). The temperature dependence of the current voltage characteristics of a Si Esaki diode in the range from 4.2 to 325 K indicated that both the peak current and the excess current are dominated by quantum mechanical tunneling rather than by recombination. The temperature dependence of the peak and valley currents is due to the band gap dependence of the tunneling probability.
Improved procedure for the construction of neoglycolipids having antigenic and lectin-binding activities, from reducing oligosaccharides (1988)

Conditions have been established for the rapid and efficient conjugation of reducing oligosaccharides (di- to deca-saccharides) to dipalmitoyl phosphatidylethanolamine. The resulting neoglycolipids derived from several naturally occurring oligosaccharides and a series of N-linked high-mannose-type oligosaccharides released by hydrazinolysis from RNAase B showed specific and potent reactivities, as appropriate, with monoclonal antibodies to blood group Lewis(b), blood group A or a stage-specific embryonic (SSEA-1) antigen, or the lectin concanavalin A.
Graph-based data fusion of pedometer and WiFi measurements for mobile indoor positioning (2014)

We propose a graph-based, low-complexity sensor fusion approach for ubiquitous pedestrian indoor positioning using mobile devices. We employ our fusion technique to combine relative motion information based on step detection with WiFi signal strength measurements. The method is based on the well-known particle filter methodology. In contrast to previous work, we provide a probabilistic model for location estimation that is formulated directly on a fully discretized, graph-based representation of the indoor environment. We generate this graph by adaptive quantization of the indoor space, removing irrelevant degrees of freedom from the estimation problem. We evaluate the proposed method in two realistic indoor environments using real data collected from smartphones. In total, our dataset spans about 20 kilometers in distance walked and includes 13 users and four different mobile device types. Our results demonstrate that the filter requires an order of magnitude less particles than state-of-the-art approaches while maintaining an accuracy of a few meters. The proposed low-complexity solution not only enables indoor positioning on less powerful mobile devices, but also saves much-needed resources for location-based end-user applications which run on top of a localization service.
85nm gate length enhancement and depletion mode InSb quantum well transistors for ultra high speed and very low power digital logic applications (2006)

We demonstrate for the first time 85nm gate length enhancement and depletion mode InSb quantum well transistors with unity gain cutoff frequency, f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</sub> , of 305 GHz and 256 GHz, respectively, at 0.5V V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">DS</sub> , suitable for high speed, very low power logic applications. The InSb transistors demonstrate 50% higher unity gain cutoff frequency, f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</sub> , than silicon NMOS transistors while consuming 10 times less active power
Feste Lösungen durch Schmelzextrusion - ein integriertes Herstellkonzept (2000)

Die Schmelzextrusionstechnologie stellt einen effizienten Herstellungsprozeß für orale Arzneiformen dar. Aus der Prozeß Technologie Extrusion wurde ein Drug-Delivery System entwickelt. Einhergehend mit der Möglichkeit, amorphe Wirkstoffzubereitungen durch Schmelzextrusion in einem lösemittelfreiem Prozeß erhalten zu können, sind die In-Situ-Salzbildung, die Homogenisierung der Korngrößenverteilung und die maßgeschneiderte Einstellung von Freisetzungsprofilen weitere Stärken des Schmelzextrusionsprozesses.
Adding a Test for Human Papillomavirus DNA to Cervical-Cancer Screening (2003)

It is now clear that virtually all squamous-cell cervical carcinomas contain one of 18 types of human papillomavirus (HPV) DNA, as shown definitively in the article by Muñoz et al. in this issue of the Journal (pages 518–527). Although the observation that HPV DNA is routinely detected in cervical cancers is not proof that it has a causal role, the relative risk of cervical cancer associated with high-risk types of HPV is even higher than the risk of lung cancer associated with smoking. Several oncogenes have been identified in high-risk (oncogenic) types of HPV, and the biologic mechanisms of malignant . . .
Counting absolute number of molecules using unique molecular identifiers (2011)

Abstract Advances in molecular biology have made it easy to identify different DNA or RNA species and to copy them. Identification of nucleic acid species can be accomplished by reading the DNA sequence; currently millions of molecules can be sequenced in a single day using massively parallel sequencing. Efficient copying of DNA-molecules of arbitrary sequence was made possible by molecular cloning, and the polymerase chain reaction. Differences in the relative abundance of a large number of different sequences between two or more samples can in turn be measured using microarray hybridization and/or tag sequencing. However, determining the relative abundance of two different species and/or the absolute number of molecules present in a single sample has proven much more challenging. This is because it is hard to detect individual molecules without copying them, and even harder to make defined number of copies of molecules. We show here that this limitation can be overcome by using unique molecular identifiers (umis), which make each molecule in the sample distinct.
Synthesis and evaluation of the analgesic and antiinflammatory activities of N-substituted salicylamides. (1989)

Some N-heterocyclic salicylamide derivatives were prepared by fusion of phenyl salicylate and heterocyclic amines, whereas other ones were synthesized by ring closure using N-salicyloyl-N'-anthranylhydrazine as starting material. All the compounds were tested for their analgesic and antiinflammatory activities, as well as for their acute toxicity and ulcerogenic effects, in order to ascertain if the N-substitution would offer any advantages. Some derivatives were more effective than salicylamide and ulcerogenic activity was variably lowered.
Synthesis of isomaltooligosaccharides and oligodextrans in a recycle membrane bioreactor by the combined use of dextransucrase and dextranase (2004)

A recycle ultrafiltration membrane reactor was used to develop a continuous synthesis process for the production of isomaltooligosaccharides (IMO) from sucrose, using the enzymes dextransucrase and dextranase. A variety of membranes were tested and the parameters affecting reactor stability, productivity, and product molecular weight distribution were investigated. Enzyme inactivation in the reactor was reduced with the use of a non-ionic surfactant but its use had severe adverse effects on the membrane pore size and porosity. During continuous isomaltooligosaccharide synthesis, dextransucrase inactivation was shown to occur as a result of the dextranase activity and it was dependent mainly on the substrate availability in the reactor and the hydrolytic activity of dextranase. Substrate and dextranase concentrations (50-200 mg/mL(-1) and 10-30 U/mL(-1), respectively) affected permeate fluxes, reactor productivity, and product average molecular weight. The oligodextrans and isomaltooligosaccharides formed had molecular weights lower than in batch synthesis reactions but they largely consisted of oligosaccharides with a degree of polymerization (DP) greater than 5, depending on the synthesis conditions. No significant rejection of the sugars formed was shown by the membranes and permeate flux was dependent on tangential flow velocity.
Direitos e deveres das mulheres e dos homens na Idade Média: o testemunho dos Costumes e Foros portugueses. (2015)

Neste trabalho pretendemos analisar o perfil das mulheres, os papeis de genero e as relacoes entre homens e mulheres nos concelhos medievais portugueses (Alfaiates, Castelo Rodrigo, Castelo Melhor, Castelo Bom, Guarda, Santarem, Evora e Beja), na Idade Media, tendo como ponto de partida os seus costumes e foros (seculo XIII). Utilizamos exclusivamente esta fonte, porque nos oferece multiplos campos de analise para o estudo da sociedade municipal medieval
Sequence of a full length cDNA coding for human protein HC (α1microglobulin) (1986)

Journal Article Sequence of a full length cDNA coding for human protein HC (α1microglobulin) Get access Cinzia Traboni, Cinzia Traboni Search for other works by this author on: Oxford Academic PubMed Google Scholar Riccardo Cortese Riccardo Cortese 1European Molecular Biology Laboratory, Meyerhofstrasse6900 Heidelberg, FRG Search for other works by this author on: Oxford Academic PubMed Google Scholar Nucleic Acids Research, Volume 14, Issue 15, 11 August 1986, Page 6340, https://doi.org/10.1093/nar/14.15.6340 Published: 11 August 1986 Article history Received: 19 June 1986 Published: 11 August 1986
Synthesis of g‐C3N4 Nanoparticles in Mesoporous Silica Host Matrices (2005)

Highly crystalline g-C3N4 nanoparticles have been synthesized from molecular precursors via polycondensation, using mesoporous silica with different pore sizes as host matrices. The particles isolated after removal of the host matrix (see Figure) are characterized using electron microscopy and various spectroscopic techniques. Structural and electronic size effects are identified by comparing nanoparticles that are 5, 13, and 60 nm in diameter. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2089/2005/c1756_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Diffuse Reflectance Infrared Spectroscopic Characterization of Silica Dehydroxylation (1990)

Diffuse reflectance Fourier transform infrared spectroscopy (DRIFTS) is employed to study the dehydroxylation of amorphous silica. Dehydroxylation results in the appearance of infrared absorption bands at 1022, 1107, and 1240 cm −1 assigned to asymmetric stretching vibrations for three different siloxane bridge types. The 1107-cm −1 absorbance band represents a siloxane bridge that is indistinguishable from bulk species. The 1022-cm −1 absorbance band represents a siloxane bridge with a bond angle that is smaller than the bulk, with little change in the stretching vibration force constant. The 1240-cm −1 absorbance band derives from a siloxane bridge characterized by a stretching force constant significantly larger than that of bulk siloxane bridges. This band may be indicative of a highly strained or broken siloxane bridge.
Intelligent network overview (1993)

The International Consultative Committee for Telephone and Telegraph (CCITT) program of work that addresses global international intelligent network (IN) standards and a framework for the standardized evolution of IN are described. Bell Communication Research's (Bellcore's) IN work, referred to as the Advanced Intelligent Network (AIN), is also discussed in relation to the CCITT IN Recommendations. In addition, IN activities of the European Telecommunications Standards Institute (ETSI) and the Telecommunications Technology Committee (TTC) of Japan are described.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Environmental Effects on Oleic Acid in Soybean Seed Oil of Plant Introductions with Elevated Oleic Concentration (2009)

ABSTRACT Soybean [ Glycine max (L.) Merr.] oil with oleic acid (18:1) content &gt;500 g kg −1 is desirable for a broader role in food and industrial uses. Seed oil in commercially grown soybean genotypes averages about 230 g kg −1 oleic acid. Some maturity group (MG) II to V plant introductions (PIs) have elevated oleic concentrations of 300 to 500 g kg −1 Temperature of the growing environment during the reproductive growth stage affects oleic concentration in soybean oil. The objective of this study was to evaluate stability of oleic acid content among 15 PIs with elevated 18:1 and three checks grown in 16 environments. Oleic acid concentration of the high 18:1 checks N98‐4445A and M23 ranged from 383 to 694 g kg −1 and 428 to 572 g kg −1 with averages of 575 g kg −1 and 508 g kg −1 , respectively. The PIs with the highest 18:1 were MG II to III, with most lines averaging &gt;400 g kg −1 oleic acid concentration over 16 environments. Generally, PIs in MG II to III were less stable across environments than those in MG V. However, MG III PI 379559D ranged from 381 to 513 g kg −1 with an average 439 g kg −1 oleic acid concentration and was the most stable in oleic acid content of the 15 PIs studied. PI379559D was more stable than N98‐4445A or M23. PI417360 and PI506852 averaged highest in 18:1 (&gt;330 g kg −1 ) among MG V PIs studied. Combining genes from these PIs and other sources with elevated 18:1 may be useful in developing higher oleic acid soybean genotypes.
LyF-1, a transcriptional regulator that interacts with a novel class of promoters for lymphocyte-specific genes. (1991)

We have studied transcriptional control of the murine terminal deoxynucleotidyltransferase (TdT) gene, which is activated specifically in immature B and T lymphocytes. This analysis has led to the identification and purification of a 50-kDa sequence-specific DNA-binding protein, LyF-1, that interacts with the approximate consensus sequence PyPyTGGGAGPu and is enriched in cells at most stages of B- and T-cell differentiation. LyF-1 binds tightly to an element in the TdT promoter that we show is required for transcription in lymphocytes. LyF-1 also interacts with an element in the immunoglobulin mu enhancer, called microB, that was recently shown to be important for lymphocyte-specific enhancer activity. Moreover, LyF-1 binds to the promoters for the lymphocyte-specific genes lambda 5, VpreB, and lck, all of which we speculate have additional features in common with the TdT promoter. Thus, LyF-1 may be a general transcriptional activator for genes whose expression is restricted to the B- and/or T-lymphocyte lineages.
Safety results from a pooled analysis of randomized, controlled phase II and III clinical trials and interim data from an open‐label extension trial of the interleukin‐12/23 monoclonal antibody, briakinumab, in moderate to severe psoriasis (2012)

Pooled briakinumab safety results from five parent studies and an OLE suggest increased rates of infections, malignancies and MACE, and that patients receiving anti-IL-12/23 treatment for moderate to severe psoriasis should be monitored for these potential safety signals.