gebhart/patrepeval huggingface dataset:
Attributed Social Network Embedding (2018)

Embedding network data into a low-dimensional vector space has shown promising performance for many real-world applications, such as node classification and entity retrieval. However, most existing methods focused only on leveraging network structure. For social networks, besides the network structure, there also exists rich information about social actors, such as user profiles of friendship networks and textual content of citation networks. These rich attribute information of social actors reveal the homophily effect, exerting huge impacts on the formation of social networks. In this paper, we explore the rich evidence source of attributes in social networks to improve network embedding. We propose a generic Attributed Social Network Embedding framework (ASNE), which learns representations for social actors (i.e., nodes) by preserving both the structural proximity and attribute proximity. While the structural proximity captures the global network structure, the attribute proximity accounts for the homophily effect. To justify our proposal, we conduct extensive experiments on four real-world social networks. Compared to the state-of-the-art network embedding approaches, ASNE can learn more informative representations, achieving substantial gains on the tasks of link prediction and node classification. Specifically, ASNE significantly outperforms node2vec with an 8.2 percent relative improvement on the link prediction task, and a 12.7 percent gain on the node classification task.
Laser diode light frequency doubled to blue using a lithium niobate channel waveguide (1989)

Quasi-phase-matching (QFM) based on periodic modulation of the nonlinearity [1,2] is a promising and versatile technique since it makes it possible to phase-match an arbitrary wavelength by appropriate choice of the period of modulation.
Modeling and characterization of large-scale Wi-Fi traffic in public hot-spots (2011)

Server side measurements from several Wi-Fi hot-spots deployed in a nationwide network over different types of venues from small coffee shops to large enterprises are used to highlight differences in traffic volumes and patterns. We develop a common modeling framework for the number of simultaneously present customers. Our approach has many novel elements: (a) We combine statistical clustering with Poisson regression from Generalized Linear Models to fit a non-stationary Poisson process to the arrival counts and demonstrate its remarkable accuracy; (b) We model the heavy tailed distribution of connection durations through fitting a Phase Type distribution to its logarithm so that not only the tail but also the overall distribution is well matched; (c) We obtain the distribution of the number of simultaneously present customers from an M <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">t</sub> /G/∞ queuing model using a novel regenerative argument that is transparent and avoids the customarily made assumption of the queue starting empty at an infinite past; (d) Most importantly, we validate our models by comparison of their predictions and confidence intervals against test data that is not used in fitting the models.
Autonomous driving on vehicle test tracks: overview, implementation and vehicle diagnosis (2003)

This article describes the implementation of the Autonomous Driving project. Furthermore, it shows the concept of the vehicle diagnosis in detail. The vehicle diagnosis monitors a test car on a proving ground and substitutes the surveillance of a human test driver. Therefore, the human diagnostics capabilities have to be replaced by measuring equipment in order to automate the detection of malfunctions. The components of the vehicle diagnosis system and its operating principle are shown. Two test vehicles were equipped with sensors, computers and actuators (driving robots). The vehicles can be driven by a robot while the sensor system observes the entire surroundings in order to be able to avoid obstacles. Furthermore, the vehicle control can be overruled by an electronic copilot in case of an emergency.
Imaging the glycome (2008)

Molecular imaging enables visualization of specific molecules in vivo and without substantial perturbation to the target molecule's environment. Glycans are appealing targets for molecular imaging but are inaccessible with conventional approaches. Classic methods for monitoring glycans rely on molecular recognition with probe-bearing lectins or antibodies, but these techniques are not well suited to in vivo imaging. In an emerging strategy, glycans are imaged by metabolic labeling with chemical reporters and subsequent ligation to fluorescent probes. This technique has enabled visualization of glycans in living cells and in live organisms such as zebrafish. Molecular imaging with chemical reporters offers a new avenue for probing changes in the glycome that accompany development and disease.
Sidewall Carboxylic Acid Functionalization of Single-Walled Carbon Nanotubes (2003)

The reactions of single-walled carbon nanotubes (SWNTs) with succinic or glutaric acid acyl peroxides in o-dichlorobenzene at 80-90 degrees C resulted in the addition of 2-carboxyethyl or 3-carboxypropyl groups, respectively, to the sidewalls of the SWNT. These acid-functionalized SWNTs were converted to acid chlorides by derivatization with SOCl(2) and then to amides with terminal diamines such as ethylenediamine, 4,4'-methylenebis(cyclohexylamine), and diethyltoluenediamine. The acid-functionalized SWNTs and the amide derivatives were characterized by a set of materials characterization methods including attenuated total reflectance (ATR) FTIR, Raman and solid state (13)C NMR spectroscopy, transmission electron microscopy (TEM), and thermal gravimetry-mass spectrometry (TG-MS). The degree of SWNT sidewall functionalization with the acid-terminated groups was estimated as 1 in 24 carbons on the basis of TG-MS data. In comparison with the pristine SWNTs, the acid-functionalized SWNTs show an improved solubility in polar solvents, for example, alcohols and water, which enables their processing for incorporation into polymer composite structures as well as for a variety of biomedical applications.
Elicitins from Phytophthora and basic resistance in tobacco. (1995)

Elicitins are a family of small proteins secreted by species of Phytophthora. They are thought to be major determinants of the resistance response of tobacco against these oomycetes, since purified elicitins, alone and at low concentrations, can induce vigorous defense responses in tobacco (i.e., hypersensitive cell death and resistance against subsequent pathogen attack), and in vitro elicitin production by Phytophthora isolates is strongly negatively correlated with their pathogenicity on tobacco plants. A number of elicitins have been purified and their amino acid sequences have been determined and found to be conserved. A three-dimensional structure for elicitin is emerging from nuclear magnetic resonance studies. Two structural classes, alpha and beta, are distinguished by their biological effects when applied to decapitated stems or petioles; the beta class causes more necrosis on leaves and provides better subsequent protection against pathogen attack. However, both these classes of elicitins will similarly cause necrosis when each is, instead, directly infiltrated into tobacco leaf panels. Effects of elicitins on tobacco cells include rapid electrolyte leakage, changes in protein phosphorylation and amounts of active oxygen species, and later production of ethylene and capsidiol. The sites of initial interaction with tobacco cells are unknown, but the interaction appears to induce general defense-related responses.
A frequency-dependent PSTD algorithm for general dispersive media (1999)

Based on the Fourier representation of spatial derivatives, the recursive convolution approaches, and the perfectly matched layer (PML), we develop a pseudospectral time-domain (PSTD) algorithm for electromagnetic problems involving general dispersive media. As a result of the accurate representation of spatial derivatives, the PSTD algorithm for dispersive media requires only a small number of cells per minimum wavelength, significantly reducing the number unknowns. Multidimensional numerical results confirm efficacy of the PSTD algorithm for large-scale inhomogeneous media.
Calcium oxalate crystal deposition in kidneys of hypercalciuric mice with disrupted type IIa sodium-phosphate cotransporter (2008)

The most common theories about the pathogenesis of idiopathic kidney stones consider precipitation of calcium phosphate (CaP) within the kidneys critical for the development of the disease. We decided to test the hypothesis that a CaP substrate can promote the deposition of calcium oxalate (CaOx) in the kidneys. Experimental hyperoxaluria was induced by feeding glyoxylate to male mice with knockout (KO) of NaP(i) IIa (Npt2a), a sodium-phosphate cotransporter. Npt2a KO mice are hypercalciuric and produce CaP deposits in their renal tubules. Experimental hyperoxaluria led to CaOx crystalluria in both the hypercalciuric KO mice and the normocalciuric control B6 mice. Only the KO mice produced CaOx crystal deposits in their kidneys, but the CaOx crystals deposited separately from the CaP deposits. Perhaps CaP deposits were not available for a CaOx overgrowth. These results also validate earlier animal model observations that showed that CaP substrate is not required for renal deposition of CaOx and that other factors, such as local supersaturation, may be involved. The absence of CaOx deposition in the B6 mice despite extreme hyperoxaluria also signifies the importance of both calcium and oxalate in the development of CaOx nephrolithiasis.
Ontological User Profiling and Language Modeling for Personalized Information Services (2009)

With the explosive growth of the information and services deployed to the Web, there is a pressing need to develop an effective service for personalized services discovery and recommendation. Despite personalized services discovery methods have been studied by researchers before, few attempts have been made to explore ontological user profiling and probabilistic language modeling approach for service contextualization and service ranking. This paper makes a novel contribution in terms of developing an agent and ontology based user profiling mechanism to improve the service discovery processes. In particular, a novel probabilistic language modeling approach is developed to conduct service contextualization and service ranking. Our initial experimental results show that the proposed service personalization approach is promising when compared with a baseline system.
B Cell Development in the Spleen Takes Place in Discrete Steps and Is Determined by the Quality of B Cell Receptor–Derived Signals (1999)

Only mature B lymphocytes can enter the lymphoid follicles of spleen and lymph nodes and thus efficiently participate in the immune response. Mature, long-lived B lymphocytes derive from short-lived precursors generated in the bone marrow. We show that selection into the mature pool is an active process and takes place in the spleen. Two populations of splenic B cells were identified as precursors for mature B cells. Transitional B cells of type 1 (T1) are recent immigrants from the bone marrow. They develop into the transitional B cells of type 2 (T2), which are cycling and found exclusively in the primary follicles of the spleen. Mature B cells can be generated from T1 or T2 B cells. Mice with genetic deletions of elements participating in the B cell receptor signaling cascade display developmental arrest at the T1 or T2 stage. The analysis of these defects showed that the development of T2 and mature B cells from T1 precursors requires defined qualitative and quantitative signals derived from the B cell receptor and that the induction of longevity and maturation requires different signals.
Naturally Processed Peptides (1993)

Peptide presentation by major histocompatibility class I molecules, G.M. van Bleek and S.G. Nathenson the ligands of the class II major histocompatibility complex-restricted T cells, S. Demotz mass spectrometric analysis of peptides associated with the human class I MHC molecules HLA-A2.1 and HLA-B7 and identification of structural features that determine binding, V.H. Engelhard et al interactions between peptides and major histocompatibility complex molecules during antigen processing and presentation, F. Forquet et al tissue-specific expression of self peptides bound by MHC class II molecules, J.H. Freed and P. Marrack MHC class I-restricted antigen processing - lessons from natural ligands, H.-G. Rammensee et al studies on naturally processed peptides associated with MHC class II molecules, A. Rudensky and C.A. Janeway isolation and characterization of naturally processed peptides bound by class II molecules and peptides presented by normal and mutant antigen-presenting cells, A. Sette et al identification of naturally occurring peptides associated with MHC molecules, T.J. Tsomides and H.N. Eisen the dichotomy of peptide presentation by class I and class II MHC proteins, R.G. Urban et al.
The effects of practice on the functional anatomy of task performance (1998)

The effects of practice on the functional anatomy observed in two different tasks, a verbal and a motor task, are reviewed in this paper. In the first, people practiced a verbal production task, generating an appropriate verb in response to a visually presented noun. Both practiced and unpracticed conditions utilized common regions such as visual and motor cortex. However, there was a set of regions that was affected by practice. Practice produced a shift in activity from left frontal, anterior cingulate, and right cerebellar hemisphere to activity in Sylvian-insular cortex. Similar changes were also observed in the second task, a task in a very different domain, namely the tracing of a maze. Some areas were significantly more activated during initial unskilled performance (right premotor and parietal cortex and left cerebellar hemisphere); a different region (medial frontal cortex, "supplementary motor area") showed greater activity during skilled performance conditions. Activations were also found in regions that most likely control movement execution irrespective of skill level (e.g., primary motor cortex was related to velocity of movement). One way of interpreting these results is in a "scaffolding-storage" framework. For unskilled, effortful performance, a scaffolding set of regions is used to cope with novel task demands. Following practice, a different set of regions is used, possibly representing storage of particular associations or capabilities that allow for skilled performance. The specific regions used for scaffolding and storage appear to be task dependent.
The CD20 Calcium Channel Is Localized to Microvilli and Constitutively Associated with Membrane Rafts (2004)

CD20 is a B cell-specific membrane protein that functions in store-operated calcium entry and serves as a useful target for antibody-mediated therapeutic depletion of B cells. Antibody binding to CD20 induces a diversity of biological effects, some of which are dependent on lipid rafts. Rafts are isolated as low density detergent-resistant membranes, initially characterized using Triton X-100. We have previously reported that CD20 is soluble in 1% Triton but that antibodies induce the association of CD20 with Triton-resistant rafts. However, by using several other detergents to isolate rafts and by microscopic co-localization with a glycosylphosphatidylinositol-linked protein, we show in this report that CD20 is constitutively raft-associated. CD20 was distributed in a punctate pattern on the cell surface as visualized by fluorescence imaging and was also localized to microvilli by electron microscopy. The mechanism underlying antibody-induced association of CD20 with Triton-resistant rafts was investigated and found not to require cellular ATP, kinase activity, actin polymerization, or antibody cross-linking but was dependent on the epitope recognized. Thus, antibody-induced insolubility in 1% Triton most likely reflects a transition from relatively weak to strong raft association that occurs as a result of a conformational change in the CD20 protein.
A B-Spline Least-Squares Surface-Fitting Method for Articular Surfaces of Diarthrodial Joints (1993)

The B-spline least-squares surface-fitting method is employed to create geometric models of diarthrodial joint articular surfaces. This method provides a smooth higher-order surface approximation from experimental three-dimensional surface data that have been obtained with any suitable measurement technique. Akima's method for surface interpolation is used to provide complete support to the B-spline surface. The surface-fitting method is successfully tested on a known analytical surface, and is applied to the human distal femur. Applications to other articular surfaces are also shown. Results show that this method is precise, highly flexible, and can be successfully applied to a large variety of articular surface shapes.
Human neutrophil elastase in temporal (giant cell) arteritis: plasma and immunohistochemical studies. (1998)

High levels of pHNE-alpha1AT were associated with TA. Our preliminary results indicate this could be a diagnostic marker for TA. Further studies are needed to confirm its reliability. Because HNE was not detected locally, no conclusions can be drawn as to its pathogenic role in TA.
Can Metal–Organic Framework Materials Play a Useful Role in Large‐Scale Carbon Dioxide Separations? (2010)

Metal-organic frameworks (MOFs) are a fascinating class of crystalline nanoporous materials that can be synthesized with a diverse range of pore dimensions, topologies, and chemical functionality. As with other well-known nanoporous materials, such as activated carbon and zeolites, MOFs have potential uses in a range of chemical separation applications because of the possibility of selective adsorption and diffusion of molecules in their pores. We review the current state of knowledge surrounding the possibility of using MOFs in large-scale carbon dioxide separations. There are reasons to be optimistic that MOFs may make useful contributions to this important problem, but there are several critical issues for which only very limited information is available. By identifying these issues, we provide what we hope is a path forward to definitively answering the question posed in our title.
Uniformly redundant array imaging of laser driven compressions: preliminary results (1979)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text E. E. Fenimore, T. M. Cannon, D. B. Van Hulsteyn, and P. Lee, "Uniformly redundant array imaging of laser driven compressions: preliminary results," Appl. Opt. 18, 945-947 (1979) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
The Role of Publishing Houses in Developing Legal Research and Publication: The United States (1990)

The Role of Publishing Houses in Developing Legal Research and Publication: The United States Byron D. Cooper Byron D. Cooper 1Byron D. Cooper is Law Library Director and Associate Professor of Law, University of Detroit School of Law. The author is grateful to the University of Detroit School of Law for a Faculty Research Grant, which underwrote the three surveys described infra nn. 113, 139, & 145. In addition, he would like to thank Evelyn Tadros for helping with these surveys and to acknowledge in general the expert research assistance provided by the staff of the University of Detroit Law Library. Search for other works by this author on: Oxford Academic Google Scholar The American Journal of Comparative Law, Volume 38, Issue suppl_1, Supplement 1990, Pages 611–640, https://doi.org/10.2307/840562 Published: 01 December 1990
Concentration and purification of beef extract mock eluates from water samples for the detection of enteroviruses, hepatitis A virus, and Norwalk virus by reverse transcription-PCR (1995)

In this study we developed a concentration and purification procedure to facilitate reverse transcription (RT)-PCR detection of enteric viruses in water sample concentrates obtained by conventional filter adsorption-elution methods. One liter of beef extract-glycine eluate with or without humic acid and seeded with poliovirus type 1, hepatitis A virus, and Norwalk virus was used as a model system, and the eluent was further processed for RT-PCR compatibility. The sample concentration and purification procedures which we used included polyethylene glycol precipitation, Pro-Cipitate precipitation, a second polyethylene glycol precipitation, spin column chromatography, and ultrafiltration. The sample volumes were reduced from 1 liter to 20 to 50 microliters, and the samples were purified enough so that viruses could be detected by the RT-PCR. The ability to detect low levels of enteric viruses by molecular techniques was compared directly with the ability to detect enteric viruses by cell culture infectivity procedures. As little as 3 PFU of poliovirus type 1 in an initial 1 liter of mock eluate was detected by the RT-PCR.
Enhancing CAR T cell persistence through ICOS and 4-1BB costimulation (2018)

Successful tumor eradication by chimeric antigen receptor-expressing (CAR-expressing) T lymphocytes depends on CAR T cell persistence and effector function. We hypothesized that CD4+ and CD8+ T cells may exhibit distinct persistence and effector phenotypes, depending on the identity of specific intracellular signaling domains (ICDs) used to generate the CAR. First, we demonstrate that the ICOS ICD dramatically enhanced the in vivo persistence of CAR-expressing CD4+ T cells that, in turn, increased the persistence of CD8+ T cells expressing either CD28- or 4-1BB-based CARs. These data indicate that persistence of CD8+ T cells was highly dependent on a helper effect provided by the ICD used to redirect CD4+ T cells. Second, we discovered that combining ICOS and 4-1BB ICDs in a third-generation CAR displayed superior antitumor effects and increased persistence in vivo. Interestingly, we found that the membrane-proximal ICD displayed a dominant effect over the distal domain in third-generation CARs. The optimal antitumor and persistence benefits observed in third-generation ICOSBBz CAR T cells required the ICOS ICD to be positioned proximal to the cell membrane and linked to the ICOS transmembrane domain. Thus, CARs with ICOS and 4-1BB ICD demonstrate increased efficacy in solid tumor models over our current 4-1BB-based CAR and are promising therapeutics for clinical testing.
Roles of FtsA and FtsZ in Activation of Division Sites (1998)

Increasing FtsZ induces the formation of minicells at cell poles but does not increase the frequency or timing of central divisions. A coordinate increase in both FtsZ and FtsA, however, increases the frequency of both polar and central divisions.
A high-resolution optical see-through head-mounted display with eyetracking capability (2013)

A head-mounted display system with fully-integrated eyetracking capability offers multi-fold benefits, not only to fundamental scientific research but also to emerging applications of such technology. A key limitation of the state-of-the-art eyetracked head-mounted display (ET-HMD) technology is the lack of compactness and portability. In this paper, we present an innovative design of a high resolution optical see-through ET-HMD system based on freeform optical technology. A prototype system is demonstrated, which offers a goggle-like compact form factor, non-obstructive see-through field of view and true high-definition image resolution for the virtual display. The see-through view, via the combination of a freeform prism and corrector, achieved better than 0.5 arc minute of angular resolution for the central region of approximately 40-degrees to ensure minimal impacts on the see-through vision of an HMD user.