gebhart/patrepeval huggingface dataset:
Estimating uncertainties in integrated reservoir studies (2004)

To make sound investment decisions, decision makers need accurate estimates of the uncertainties present in forecasts of reservoir performance. In this work I propose a method, the integrated mismatch method, that incorporates the misfit in the history match into the estimation of uncertainty in the prediction. I applied the integrated mismatch method, which overcomes some deficiencies of existing methods, to uncertainty estimation in two reservoir studies and compared results to estimations from existing methods. The integrated mismatch method tends to generate smaller ranges of uncertainty than many existing methods. When starting from nonoptimal reservoir models, in some cases the integrated mismatch method is able to bracket the true reserves value while other methods fail to bracket it. The results show that even starting from a nonoptimal reservoir model, but as long as the experimental designs encompass the true case parameters, the integrated mismatch method brackets the true reserves value. If the experimental designs do not encompass all the true case parameters, but the true reserves value is covered by the experiments, the integrated mismatch method may still bracket the true case. This applies if there is a strong correlation between mismatch and closeness to the true reserves value. The integrated mismatch method does not need a large number of simulation runs for the uncertainty analysis, while some other methods need hundreds of runs.
Introduction, modification, and characterization of functional groups on the surface of low-density polyethylene film (1977)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIntroduction, modification, and characterization of functional groups on the surface of low-density polyethylene filmJames R. Rasmussen, Erwin R. Stedronsky, and George M. WhitesidesCite this: J. Am. Chem. Soc. 1977, 99, 14, 4736–4745Publication Date (Print):June 1, 1977Publication History Published online1 May 2002Published inissue 1 June 1977https://pubs.acs.org/doi/10.1021/ja00456a035https://doi.org/10.1021/ja00456a035research-articleACS PublicationsRequest reuse permissionsArticle Views1316Altmetric-Citations165LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Low-Complexity Two-Stage Carrier Phase Estimation for 16-QAM Systems using QPSK Partitioning and Maximum Likelihood Detection (2011)

A feedforward carrier phase estimation algorithm using a modified QPSK partition approach followed by maximum-likelihood (ML) detection is proposed. Results demonstrate complexity reduction by more than a factor of 2 compared with other techniques.
Enhanced Activity and Altered Specificity of Phospholipase A 2 by Deletion of a Surface Loop (1989)

Protein engineering and x-ray crystallography have been used to study the role of a surface loop that is present in pancreatic phospholipases but is absent in snake venom phospholipases. Removal of residues 62 to 66 from porcine pancreatic phospholipase A2 does not change the binding constant for micelles significantly, but it improves catalytic activity up to 16 times on micellar (zwitterionic) lecithin substrates. In contrast, the decrease in activity on negatively charged substrates is greater than fourfold. A crystallographic study of the mutant enzyme shows that the region of the deletion has a well-defined structure that differs from the structure of the wild-type enzyme. No structural changes in the active site of the enzyme were detected.
Construction of Varicella-Zoster Virus Recombinants from Parent Oka Cosmids and Demonstration that ORF65 Protein Is Dispensable for Infection of Human Skin and T Cells in the SCID-hu Mouse Model (2003)

We generated an ORF65 deletion mutant by using a cosmid system constructed from the genome of a low-passage clinical isolate (P-Oka). Using the SCID-hu mouse model, we demonstrated that the ORF65 protein is dispensable for viral replication in skin and T cells, which are critical host cell targets during primary varicella-zoster virus infection.
Biofilms can be dispersed by focusing the immune system on a common family of bacterial nucleoid-associated proteins (2011)

Bacteria that cause chronic and/or recurrent diseases often rely on a biofilm lifestyle. The foundation of the biofilm structure is the extracellular polymeric substance (EPS) that acts as a barrier to both effectors of the immune system and antimicrobial agents. Recent work has highlighted extracellular DNA (eDNA) as a key component common to many pathogenic biofilms. Here, we show that the DNABII family of proteins, well known for their strong structural influences on intracellular DNA, was also critical for the integrity of the EPS matrix of biofilms that contain eDNA. In fact, antisera derived against a purified Escherichia coli DNABII family member rapidly disrupts the biofilm EPS formed by multiple human pathogens in vitro. In addition, when a member of this family of proteins was used as an immunogen in an animal model in which the bacteria had already formed a robust biofilm at the site of infection, the resultant targeted immune response strongly ameliorated this biofilm disease in vivo. Finally, this methodology to debulk the biofilm of EPS was shown to work synergistically with otherwise ineffective traditional anti-microbial approaches in vitro. We discuss the prospects for targeting DNABII family members as a potential universal strategy for treating biofilm diseases.
Creatine monohydrate and resistance training increase bone mineral content and density in older men. (2006)

Our purpose was to determine the effects of creatine supplementation combined with resistance training on bone mineral content and density in older men. Twenty-nine older men (age 71 y) were randomized (double blind) to receive creatine (0.3 g/kg creatine for 5 d and 0.07 g/kg thereafter) or placebo while participating in resistance training (12 weeks). Bone mineral content and density were determined by dual energy X-ray absorptiometry before and after training. There was a time main effect for whole-body and leg bone mineral density (p < or = 0.05) with these measures increasing by approximately 0.5%, and 1%, respectively in the combined groups. There was a group by time interaction for arms bone mineral content, with the group receiving creatine increasing by 3.2% (p < 0.01) and the group receiving placebo decreasing by 1.0% (not significant). Changes in lean tissue mass of the arms correlated with changes in bone mineral content of the arms (r = 0.67; p < 0.01). Resistance training of 12 weeks increases bone mineral density in older men and creatine supplementation may provide an additional benefit for increasing regional bone mineral content. The increase in bone mineral content may be due to an enhanced muscle mass with creatine, with potentially greater tension on bone at sites of muscle attachment.
Cutaneous Melanoma (1991)

CUTANEOUS melanoma has become a common form of cancer.1 Decades of steady increases in the incidence and mortality rates of cutaneous malignant melanoma have sparked global interest in the nature of this cancer.2 3 4 5 6 Recent research has advanced our understanding of cutaneous melanoma and its biology, natural history, and treatment.7 This article reviews the current state of knowledge of melanoma and outlines approaches to treatment and control.EpidemiologyThe incidence of melanoma continues to rise throughout the world (Table 1). In the United States, the incidence of melanoma has almost tripled in the past four decades, growing faster than that of . . .
Phantom limb pain: A literature review (2018)

Since the phantom limb sensation was first described by the French military surgeon Ambroise Pare in the 16th century, the number of studies surrounding phantom limb pain has increased every year. Especially in recent decades, scientists have achieved a better understanding of the mechanism and treatment of phantom limb pain. Although many hypotheses have been agreed and many treatments have been proven effective, scientists still do not have a very systematic understanding of the phantom limbs. The purpose of this review article is to summarize recent researches focusing on phantom limb in order to discuss its definition, mechanisms, and treatments.
Duration of Glutamate Release After Acute Ischemic Stroke (1997)

The presence of glutamate increase in the CSF cannot be documented for greater than 6 hours in stable ischemic stroke. The sustained elevation of glutamate observed in progressing stroke suggests that the window to prevent neurological deterioration may be wider.
Beyond the High Efficiency Video Coding standard: an overview (2017)

This paper presents advancements on the state of the art High Efficiency Video Coding Standard (HEVC), in the context of the Joint Exploration Model (JEM). This model is still under development from the ITU and promises significant improvements in the Rate Distortion Performance of HEVC through an assortment of coding tools. These tools are presented in algorithmic detail and comparisons between HEVC and JEM are drawn.
Evaluation of granulocytic ehrlichiosis in dogs of Missouri, including serologic status to Ehrlichia canis, Ehrlichia equi, and Borrelia burgdorferi (1992)

Canine granulocytic ehrlichiosis was diagnosed in 37 dogs by finding ehrlichial morulae in 0.1 to 26.2% of their blood neutrophils and eosinophils. All 37 dogs had clinical signs of arthritis or muscular stiffness. Titer to Ehrlichia canis was determined in sera from 31 of the 37 dogs; 25 dogs had titer ranging from 1:20 to 1:5,120. In the other 6 dogs, titer to E canis was less than 1:10. The most common hematologic abnormality in these dogs, other than rickettsiemia, was thrombocytopenia. Granulocytes infected with ehrlichial organisms were not found in another 10 dogs that had clinical signs of arthritis or muscular stiffness. Of these 10 dogs, 3 had titer to E canis ranging from 1:40 to 1:320. Titer in the other 7 dogs was less than 1:10. Ehrlichial morulae were not found in the granulocytes of 18 healthy dogs. Of these 18 dogs, 9 had titer to E canis ranging from 1:20 to 1:5,120. Titer in the other 9 dogs was less than 1:10 Titer to Borrelia burgdorferi was determined in dogs with granulocytic ehrlichiosis, arthritic dogs without detected rickettsiemia, and in healthy dogs. Low titer determined by 2 laboratories was considered to be nonspecific reaction in all 3 groups of dogs and, thus, did not indicate that the arthritic disorders were attributable to canine borreliosis.
Mechanistic Studies of the Electro-oxidation Pathway of Ammonia in Several Room-Temperature Ionic Liquids (2007)

A mechanistic study of the direct oxidation of ammonia has been reported in several room-temperature ionic liquids (RTILs), namely, [C4mim][BF4], [C4mim][OTf], [C2mim][NTf2], [C4mim][NTf2], and [C4mim][PF6], on a 10 μm diameter Pt microdisk electrode. In four of the RTILs studied, the cyclic voltammetric analysis suggests that ammonia is initially oxidized to nitrogen, N2, and protons, which are transferred to an ammonia molecule, forming NH4+ via the protonation of the anion(s) (A-). In contrast, NH4+ is formed first in [C4mim][PF6], followed by the protonated anion(s), HA. In all five RTILs, both HA and NH4+ are reduced at the electrode surface, forming hydrogen gas, which is then oxidized. The effect of changing the RTIL anion is discussed, and this may have implications in the defining of pKa in RTIL media. This work also has implications in the possible amperometric sensing of ammonia gas.
Networked virtual worlds (2002)

Networked virtual worlds allow multiple virtual worlds connected on a network to share information with one another. Developing such virtual worlds is, however, fraught with many difficulties. Handling both the networking and user interface needs of virtual worlds in an efficient manner poses interesting trade-off-options. In this paper, we discuss the key requirements of networked virtual worlds and describe a system called BrickNet that addresses these requirements.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
An image reconstruction method using GPR data (1999)

The spatial resolution of a ground penetrating radar (GPR) system using traditional interpretation methods is largely dependent on the isolations of echoes. It is difficult to identify weak echoes that are mixed with either direct waves or other larger echoes; especially, when the media is absorptive, the reflections cannot be identified from the tail of the direct wave. The authors present an iterative algorithm to reconstruct the image of the subsurface using time-domain waveforms. The forward modeling employed in the algorithm is derived from the transmission line matrix (TLM) method with a perfect matched layer (PML) absorbing boundary. One-dimensional (1D) inversion algorithm is briefly described, based on which, a two-dimensional (2D) inversion method is developed. The inversion algorithm proceeds iteratively in space and time step by step. The inversion algorithm is tested in cases in which both lD and 2D variations exist. The developed inversion method is used to reconstruct the images of buried objects using GPR data with echoes buried in the direct waves. The results show a superior resolution and stability.
Topical Use of Tetracycline in the Treatment of Acne (1976)

A group of 75 subjects with moderate or severe acne was divided by random selection into three treatment groups. One group was treated with a topically applied placebo liquid and with 500 mg of orally administered tetracycline hydrochloride daily; one group received orally administered lactose capsules and topically applied placebo liquid each day; and one group was treated with orally administered lactose capsules and with a topical preparation containing tetracycline hydrochloride and n-decylmethyl sulfoxide, an agent intended to enhance antibiotic penetration. At the conclusion of the 13-week study and at several points during the study, the conditions of the subjects receiving topically or orally administered tetracycline hydrochloride were significantly (P less than .05) more improved than the conditions of the subjects receiving lactose capsules and the topically applied placebo liquid. However, there was no significant difference between the effects of topically and orally administered tetracycline hydrochloride.
Conversion of Fructose into 5‐(Hydroxymethyl)furfural in Sulfolane (2011)

Sulfolane, an industrial solvent, allows for the efficient conversion of fructose into 5-(hydroxymethyl)furfural (HMF), a key platform chemical. Yields of ≥90 % are attainable with catalytic HBr in 1 h at 100 °C. The use of an inexpensive catalyst at a low concentration, low temperature, and short reaction time makes the process amenable for large-scale access to HMF.
NIST Recommended Practice Guide Fractography of Ceramics and Glasses (2016)

Certain commercial entities, equipment, or materials may be identified in this document in order to describe an experimental procedure or concept adequately. Such identification is not intended to imply recommendation or
Lung cancer mortality risk among breast cancer patients treated with anti‐estrogens (2011)

Compared with expected outcomes in the general population, breast cancer patients receiving anti-estrogen treatment for breast cancer had lower lung cancer mortality. This study further supports the hypothesis that estrogen therapy modifies lung cancer prognosis.
Analysis and design-optimization of LCC resonant inverter for high-frequency AC distributed power system (1995)

The analysis and design of an LCC resonant inverter for a 20 kHz AC distributed power system are presented. Several resonant converter topologies are assessed to determine their suitability for high efficiency power conversion, under resistive and reactive loads. Two LCC-resonant inverter designs were implemented. One with all switches operating with zero voltage switching (ZVS), and another with two switches operating with ZVS and two switches with zero current switching (ZCS). The experimental results are presented along with a performance comparison of the two versions.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Oxidation of Highly Unstable <4 nm Diameter Gold Nanoparticles 850 mV Negative of the Bulk Oxidation Potential (2012)

Here we describe the oxidation of <4 nm diameter Au nanoparticles (NPs) attached to indium tin oxide-coated glass electrodes in Br(-) and Cl(-) solution. Borohydride reduction of AuCl(4)(-) in the presence of hexanethiol or trisodium citrate (15 min) led to Au NPs <4 nm in diameter. After electrochemical and ozone removal of the hexanthiolate ligands from the thiol-coated Au NPs, Au oxidation peaks appeared in the range 0-400 mV vs Ag/AgCl (1 M KCl), which is 850-450 mV negative of the bulk Au oxidation peak near 850 mV. The oxidation potential of citrate-coated Au NPs is in the 300-500 mV range and those of 4 and 12 nm diameter Au NPs in the 660-780 mV range. The large negative shift in potential agrees with theory for NPs in the 1-2 nm diameter range. The oxidation potential of Au in Cl(-) solution is positive of that in Br(-) solution, but the difference decreases dramatically as the NP size decreases, showing less dependence on the halide for smaller NPs.
Specific Pseudomonas Immunoglobulin E Antibodies in Sera of Patients with Cystic Fibrosis (1981)

Immunoglobulin E antibodies to Psuedomonas aeruginosa were demonstrated in patients with cystic fibrosis colonized with the bacterium.
Regulation of Glucocorticoid Receptor Activity by 14–3-3-Dependent Intracellular Relocalization of the Corepressor RIP140 (2001)

Proteins belonging to the 14--3-3 family interact with various regulatory proteins involved in cellular signaling, cell cycle regulation, or apoptosis. 14--3-3 proteins have been suggested to act by regulating the cytoplasmic/nuclear localization of their target proteins or by acting as molecular scaffolds or chaperones. We have previously shown that overexpression of 14--3-3 enhances the transcriptional activity of the glucocorticoid receptor (GR), which is a member of the nuclear receptor family. In this study, we show that 14--3-3 interacts with the nuclear receptor corepressor RIP140. In transfection assays, RIP140 antagonizes 14--3-3- enhanced GR transactivation. Using colocalization studies we demonstrate that 14--3-3 can export RIP140 out of the nucleus and, interestingly, can also change its intranuclear localization. Moreover, we also observed that 14--3-3 can bind various other nuclear receptors and cofactors. In summary, our findings suggest that 14--3-3-mediated intracellular relocalization of the GR corepressor RIP140 might be a novel mechanism to enhance glucocorticoid responsiveness of target genes. They furthermore indicate a more general role for 14--3-3 protein by influencing the nuclear availability of nuclear receptor-associated cofactors.
Microbial Production of 2-Keto-l-Gulonic Acid froml-Sorbose andd-Sorbitol byGluconobacter melanogenus (1990)

Journal Article Microbial Production of 2-Keto-l-Gulonic Acid from l-Sorbose and d-Sorbitol by Gluconobacter melanogenus Get access Teruhide Sugisawa, Teruhide Sugisawa Department of Applied Microbiology, Nippon Roche Research Center, 200, Kajiwara, Kamakura, Kanagawa 247, Japan Search for other works by this author on: Oxford Academic Google Scholar Tatsuo Hoshino, Tatsuo Hoshino Department of Applied Microbiology, Nippon Roche Research Center, 200, Kajiwara, Kamakura, Kanagawa 247, Japan Search for other works by this author on: Oxford Academic Google Scholar Setsuko Masuda, Setsuko Masuda Department of Applied Microbiology, Nippon Roche Research Center, 200, Kajiwara, Kamakura, Kanagawa 247, Japan Search for other works by this author on: Oxford Academic Google Scholar Setsuko Nomura, Setsuko Nomura Department of Applied Microbiology, Nippon Roche Research Center, 200, Kajiwara, Kamakura, Kanagawa 247, Japan Search for other works by this author on: Oxford Academic Google Scholar Yutaka Setoguchi, Yutaka Setoguchi Department of Applied Microbiology, Nippon Roche Research Center, 200, Kajiwara, Kamakura, Kanagawa 247, Japan Search for other works by this author on: Oxford Academic Google Scholar Masaaki Tazoe, Masaaki Tazoe Department of Applied Microbiology, Nippon Roche Research Center, 200, Kajiwara, Kamakura, Kanagawa 247, Japan Search for other works by this author on: Oxford Academic Google Scholar Masako Shinjoh, Masako Shinjoh Department of Applied Microbiology, Nippon Roche Research Center, 200, Kajiwara, Kamakura, Kanagawa 247, Japan Search for other works by this author on: Oxford Academic Google Scholar Satoko Someha, Satoko Someha Department of Applied Microbiology, Nippon Roche Research Center, 200, Kajiwara, Kamakura, Kanagawa 247, Japan Search for other works by this author on: Oxford Academic Google Scholar Akiko Fujiwara Akiko Fujiwara Department of Applied Microbiology, Nippon Roche Research Center, 200, Kajiwara, Kamakura, Kanagawa 247, Japan Search for other works by this author on: Oxford Academic Google Scholar Agricultural and Biological Chemistry, Volume 54, Issue 5, 1 May 1990, Pages 1201–1209, https://doi.org/10.1080/00021369.1990.10870125 Published: 01 May 1990 Article history Received: 07 November 1989 Published: 01 May 1990
Conversion of Pentoses to Ethanol by Yeasts and Fungi (1989)

Fermentation of D-xylose is of interest in enhancing the yield of ethanol obtainable from lignocellulosic hydrolysates. Such hydrolysates can contain both pentoses and hexoses, and while technology to convert hexoses to ethanol is well established, the fermentation of pentoses had been problematical. To overcome the difficulty, yeasts and fungi have been sought and identified in recent years that can convert D-xylose into ethanol. However, operation of their cultures in the presence of the pentose to obtain rapid and efficient ethanol production is somewhat more complex than in the archetype alcoholic fermentation, Saccharomyces cerevisiae on D-glucose. The complexity stems, in part, from the association of ethanol accumulation in cultures where D-xylose is the sole carbon source with conditions that limit growth, by oxygen in particular, although limitation by other nutrients might also be implicated. Aspects of screening for appropriate organisms and of the parameters that play a role in determining culture variables, especially those associated with ethanol productivity, are reviewed. Performance with D-xylose as sole carbon source, in sugar mixtures, and in lignocellulosic hydrolysates is discussed. A model that involves biochemical considerations of D-xylose metabolism is presented that rationalizes the effects of oxygen on cultures where D-xylose is the sole carbon source, notably effects of the specific rate of oxygen use on the rate and extent of ethanol accumulation. Alternate methods to direct fermentation of D-xylose have been developed that depend on its prior isomerization to D-xylose, followed by fermentation of the pentulose by certain yeasts and fungi. Factors involved in the biochemistry, use, and performance of these methods, which with some organisms involves sensitivity to oxygen, are reviewed.