gebhart/patrepeval huggingface dataset:
A New Effective Test Case Prioritization for Regression Testing based on Prioritization Algorithm (2014)

Regression Testing is the process of executing the set of test cases which have passed on the previous build or release of the application under test in order to validate that the original features and functions are still working as they were previously. It is impracticable and in-sufficient resources to re-execute every test case for a program if changes occur. This problem of regression testing can be solved by prioritizing test cases. A regression test case prioritization technique involves re-ordering the execution of test suite to increase the rate of fault detection in earlier stages of testing process. In this paper, test case prioritization algorithm is proposed to identify the severe faults and improve the rate of fault detection. This proposed test case prioritization algorithm prioritizes the test cases based on four groups of practical weight factor such as: customer allotted priority, developer observed code execution complexity, changes in requirements, fault impact, completeness and traceability. The proposed prioritization technique is validated with three different validation metrics and is experimented using two projects. The effectiveness of proposed technique is achieved by comparing it with unprioritized ones and by validation metrics.
A web-enabled video indexing system (2004)

Video parsing and indexing is an important early stage of content-based video analysis. In this paper, we present a new web-enabled video indexing system that integrates Synchronized Multimedia Integration Language (SMIL) standard. New algorithms are proposed for video temporal segmentation. Sharp transition detection is achieved by an enhanced histogram-based method that is robust to illumination changes. For gradual transition detection, new features are introduced for dissolve detection. The proposed dissolve detector is based on a combined analysis of mean-variance-skewness of intensity. Compared with existing variance-based approaches, the introduced new features improve the discrimination ability on shot boundaries. We also describe methods for eliminating false positives. Experimental results show that the proposed algorithms can effectively detect shot boundaries. Detected scenes and other cinematic attributes are structured and organized by integrating HTML and SMIL. For each video file, the system generates a table-of-contents indexing file. The user-friendly interface provides web-based interaction, browsing and previewing of video content
Recombinant ob protein reduces feeding and body weight in the ob/ob mouse. (1995)

To determine whether the product of the recently cloned ob gene functions as an adipose-related satiety factor, recombinant murine ob protein was administered intraperitoneally to ob/ob mice. Monomeric ob protein given as single morning injections to groups of three animals at seven doses ranging from 5 to 100 micrograms reduced 24-h chow consumption in a dose-dependent manner from values of 81 +/- 6.8% of control (10-micrograms dose, P = 0.04) to 29 +/- 7.7% of control (100-micrograms dose, P < 0.0001). Daily injections of 80 micrograms of ob protein into six ob/ob mice for 2 wk led to an 11 +/- 1.6% decrease in body weight (P = 0.0009) and suppressed feeding to 26 +/- 4.9% of baseline (P < 0.0001), with significant reduction of serum insulin and glucose levels. The effect of recombinant ob protein on feeding was not augmented by cofactors secreted by adipose tissue, nor did exposure of adipose tissue to ob protein affect intracellular ob mRNA levels. Posttranslational modification of ob protein was not required for activity; however, addition of a hexahistidine tag to the amino terminus of the mature ob protein resulted in prolonged suppression of feeding after injection into ob/ob mice. These results demonstrate a direct effect of the ob protein to suppress feeding in the ob/ob mouse and suggest that this molecule plays a critical role in regulating total body fat content.
RNA‐guided transcriptional regulation <i>in planta</i> via synthetic <scp>dC</scp>as9‐based transcription factors (2014)

Targeted genomic regulation is a powerful approach to accelerate trait discovery and development in agricultural biotechnology. Bacteria and archaea use clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) regulatory systems for adaptive molecular immunity against foreign nucleic acids introduced by invading phages and conjugative plasmids. The type II CRISPR/Cas system has been adapted for genome editing in many cell types and organisms. A recent study used the catalytically inactive Cas9 (dCas9) protein combined with guide-RNAs (gRNAs) as a DNA-targeting platform to modulate gene expression in bacterial, yeast, and human cells. Here, we modified this DNA-targeting platform for targeted transcriptional regulation in planta by developing chimeric dCas9-based transcriptional activators and repressors. To generate transcriptional activators, we fused the dCas9 C-terminus with the activation domains of EDLL and TAL effectors. To generate a transcriptional repressor, we fused the dCas9 C-terminus with the SRDX repression domain. Our data demonstrate that dCas9 fusion with the EDLL activation domain (dCas9:EDLL) and the TAL activation domain (dCas9:TAD), guided by gRNAs complementary to selected promoter elements, induce strong transcriptional activation on Bs3::uidA targets in plant cells. Further, the dCas9:SRDX-mediated transcriptional repression of an endogenous gene. Thus, our results suggest that the synthetic transcriptional repressor (dCas9:SRDX) and activators (dCas9:EDLL and dCas9:TAD) can be used as endogenous transcription factors to repress or activate transcription of an endogenous genomic target. Our data indicate that the CRISPR/dCas9 DNA-targeting platform can be used in plants as a functional genomics tool and for biotechnological applications.
Target aspect estimation from single and multi-pass SAR images (2002)

A technique is presented for estimating the aspect of targets in SAR imagery for use in indexing, feature extraction and recognition. Aspect estimation is enhanced by combining multiple images of the same target. In order to properly combine the estimation of multiple passes, it is necessary to accurately register the images to a common coordinate frame. An algorithm for registering multiple high resolution SAR images, is presented. A global affine transformation derived from the sensor acquisition parameters is used to automatically register the images, followed by a refinement to correct for translational errors. The registered SAR images are used for improving the estimates of target orientation angles, detecting the presence of occlusion and indicating poor target segmentation.
A 0.67 μm/sup 2/ self-aligned shallow trench isolation cell (SA-STI cell) for 3 V-only 256 Mbit NAND EEPROMs (2002)

An ultra high-density NAND-structured memory cell, using a new Self-Aligned Shallow Trench Isolation (SA-STI) technology, has been developed for a high performance and low bit cost 256 Mbit flash EEPROM. The SA-STI technology results in an extremely small cell size of 0.67 /spl mu/m/sup 2/ per bit, 67% of the smallest flash memory cell reported so far, by using a 0.35 /spl mu/m technology. The key technologies to realize a small cell size are (1) 0.4 um width Shallow Trench Isolation (STI) to isolate neighboring bits and (2) a floating gate that is self-aligned with the STI, eliminating the floating-gate wings. Even though the floating-gate wings are eliminated, a high coupling ratio of 0.65 can be obtained by using the side-walls of the floating gate to increase the coupling ratio. Using this self-aligned structure. A reliable tunnel oxide can be obtained because the floating gate does not overlap the trench corners, so enhanced tunneling at the trench corner is avoided. Therefore, the SA-STI cell combines a low bit cost with a high performance and a high reliability, such as the fast programming (0.2 /spl mu/sec/byte), fast erasing (2 msec), good write/erase endurance (>10/sup 6/ cycles), and excellent read disturb characteristics(>10 years). This paper describes the process technologies and the device performance of the SA-STI cell, which can be used to realize NAND EEPROMs of 256 Mbit and beyond.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Multicarrier Faster-Than-Nyquist Transceivers: Hardware Architecture and Performance Analysis (2010)

This paper evaluates the hardware aspects of multicarrier faster-than-Nyquist (FTN) signaling transceivers. The choice of time-frequency spacing of the symbols in an FTN system for improved bandwidth efficiency is targeted towards efficient hardware implementation. This work proposes a hardware architecture for the realization of iterative decoding of FTN multicarrier modulated signals. Compatibility with existing systems has been considered for smooth switching between the faster-than-Nyquist and orthogonal signaling schemes. One such being the use of fast Fourier transforms (FFTs) for multicarrier modulation. The performance of the fixed point model is very close to that of the floating point representation. The impact of system parameters such as number of projection points, time-frequency spacing, finite wordlengths and their design tradeoffs for reduced complexity iterative decoders in FTN systems have been investigated. The FTN decoder has been designed and synthesized in both 65 nm CMOS and FPGA. From the hardware resource usage numbers it can be concluded that FTN signaling can be used to achieve higher bandwidth efficiency with acceptable complexity overhead.
Engineering a novel secretion signal for cross-host recombinant protein expression (2002)

Protein secretion is conferred by a hydrophobic secretion signal usually located at the N-terminal of the polypeptide. We report here, the identification of a novel secretion signal (SS) that is capable of directing the secretion of recombinant proteins from both prokaryotes and eukaryotes. Secretion of fusion reporter proteins was demonstrated in Escherichia coli, Saccharomyces cerevisiae and six different eukaryotic cells. Estrogen-inducibility and secretion of fusion reporter protein was demonstrated in six common eukaryotic cell lines. The rate of protein secretion is rapid and its expression profile closely reflects its intracellular concentration of mRNA. In bacteria and yeast, protein secretion directed by SS is dependent on the growth culture condition and rate of induction. This secretion signal allows a flexible strategy for the production and secretion of recombinant proteins in numerous hosts, and to conveniently and rapidly study protein expression.
Analysis and Improvement of Wired Equivalent Privacy Protocol (2019)

The aim of this study was to investigate the mechanism for the security of a wireless network. The research of the wired equivalent privacy algorithm and statistical probability model approach was adopted, in addition, a new WEP encryption algorithm based on this was introduced. The results revealed that this encryption algorithm is insufficient, and concluded the time to crack the key and the amount of encryption package needed capturing. The findings of this study may make wireless network more safety in the aspect of data transmission, thus it may be beneficial to widespread of the wireless network.
UTBOX SOI Substrate with Composite Insulating Layer (2013)

Ultra thin body and Buried Oxide (BOX) SOI substrates are of high interest for the fabrication of high performance CMOS Fully Depleted (FD) devices. We have investigated the fabrication of SOI wafers with an Ultra Thin alumina BOX (UTBOX). 300 mm SOI substrates with composite SiO2 / Alumina / SiO2 buried insulating layer have been manufactured using industrial Smart CutTM technology and a BOX dissolution stage. The substrates quality is in line with standard UTBOX products in terms of layers morphology, defectivity and thickness uniformity. It is shown that the thin SiO2 capping layers prevent the collapse of the alumina layer at high temperature and bring excellent BOX/silicon interface electrical quality with low DIT and good carrier mobility. The alumina layer exhibits a stable embedded negative charge of 3 × 1012 cm−2 and a low EOT according to its high permittivity. These unique properties make composite BOX substrates especially interesting for charge trapping applications or in FD devices manufacturing where alumina can act as an embedded etch stop layer.
Expedient chemical synthesis of sequence-specific 2',5'-oligonucleotides (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTExpedient chemical synthesis of sequence-specific 2',5'-oligonucleotidesJiro Imai and Paul F. TorrenceCite this: J. Org. Chem. 1985, 50, 9, 1418–1426Publication Date (Print):May 1, 1985Publication History Published online1 May 2002Published inissue 1 May 1985https://pubs.acs.org/doi/10.1021/jo00209a014https://doi.org/10.1021/jo00209a014research-articleACS PublicationsRequest reuse permissionsArticle Views400Altmetric-Citations33LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
&lt;title&gt;New spectroscopic methods for environmental measurement and monitoring&lt;/title&gt; (1999)

The ability to detect a broad range of chemical species in the atmosphere, geosphere, and hydrosphere, over a wide range of ambient levels and conditions, is a key enabling technology both for environmental monitoring and for sensing the presence of hazardous materials such as explosives or chemical agents. In this paper we describe several recent developments in the area of high-sensitivity chemical monitoring, including Cavity RingDown Spectroscopy (CRDS) and Raman spectroscopy. Significant improvements in the sensitivity of both ultraviolet and infrared CRDS have been made in our laboratory during the past year. Infrared CRDS, employing tunable infrared optical parametric oscillators, multilayer dielectric high-reflectivity mirrors, and membrane preconcentrator technology, may have the potential for detecting vapors from concealed explosives as well as a wide variety of volatile organic compounds present at parts-per-billion levels or below. Sensitivity enhancement techniques for Raman spectroscopy, such as Surface-Enhanced Raman Spectroscopy, may achieve similar sensitivities for samples in ultra-dilute solutions. We also address the relationship of novel monitoring techniques, such as these high-sensitivity detection methods, to current and future regulatory issues.
A Fully Pipelined Single-Precision Floating-Point Unit in the Synergistic Processor Element of a CELL Processor (2006)

The floating-point unit (FPU) in the synergistic processor element (SPE) of a CELL processor is a fully pipelined 4-way single-instruction multiple-data (SIMD) unit designed to accelerate media and data streaming with 128-bit operands. It supports 32-bit single-precision floating-point and 16-bit integer operands with two different latencies, six-cycle and seven-cycle, with 11 FO4 delay per stage. The FPU optimizes the performance of critical single-precision multiply-add operations. Since exact rounding, exceptions, and de-norm number handling are not important to multimedia applications, IEEE correctness on the single-precision floating-point numbers is sacrificed for performance and simple design. It employs fine-grained clock gating for power saving. The design has 768K transistors in 1.3 mm/sup 2/, fabricated SOI in 90-nm technology. Correct operations have been observed up to 5.6 GHz with 1.4 V and 56/spl deg/C, delivering 44.8 GFlops. Architecture, logic, circuits, and integration are codesigned to meet the performance, power, and area goals.
A Survey of ReRAM-Based Architectures for Processing-In-Memory and Neural Networks (2018)

As data movement operations and power-budget become key bottlenecks in the design of computing systems, the interest in unconventional approaches such as processing-in-memory (PIM), machine learning (ML), and especially neural network (NN)-based accelerators has grown significantly. Resistive random access memory (ReRAM) is a promising technology for efficiently architecting PIM- and NN-based accelerators due to its capabilities to work as both: High-density/low-energy storage and in-memory computation/search engine. In this paper, we present a survey of techniques for designing ReRAM-based PIM and NN architectures. By classifying the techniques based on key parameters, we underscore their similarities and differences. This paper will be valuable for computer architects, chip designers and researchers in the area of machine learning.
The NASA light-emitting diode medical program—progress in space flight and terrestrial applications (2000)

This work is supported and managed through the NASA Marshall Space Flight Center—SBIR Program. Studies on cells exposed to microgravity and hypergravity indicate that human cells need gravity to stimulate cell growth. As the gravitational force increases or decreases, the cell function responds in a linear fashion. This poses significant health risks for astronauts in long termspace flight. LED-technology developed for NASA plant growth experiments in space shows promise for delivering light deep into tissues of the body to promote wound healing and human tissue growth. This LED-technology is also biologically optimal for photodynamic therapy of cancer.
Parallel Coordinate Descent Methods for Big Data Optimization (2012)

In this work we show that randomized (block) coordinate descent methods can be accelerated by parallelization when applied to the problem of minimizing the sum of a partially separable smooth convex function and a simple separable convex function. The theoretical speedup, as compared to the serial method, and referring to the number of iterations needed to approximately solve the problem with high probability, is a simple expression depending on the number of parallel processors and a natural and easily computable measure of separability of the smooth component of the objective function. In the worst case, when no degree of separability is present, there may be no speedup; in the best case, when the problem is separable, the speedup is equal to the number of processors. Our analysis also works in the mode when the number of blocks being updated at each iteration is random, which allows for modeling situations with busy or unreliable processors. We show that our algorithm is able to solve a LASSO problem involving a matrix with 20 billion nonzeros in 2 hours on a large memory node with 24 cores.
TOXICITY OF POLYOXYETHYLENE HYDROGENATED CASTOR OIL 60 (HCO-60) IN EXPERIMENTAL ANIMALS (1993)

HCO-60, a polyoxyethylene castor oil derivative, is used as a solubilizer in the injectable formulations of lipophilic agents. This study was performed to examine the toxicity of HCO-60 in various experimental animals including dogs, monkeys, rabbits, guinea pigs and rats. With 1.25 or 2.5 mg/kg of HCO-60 injected i.v. to dogs, blood pressure decreased, flush, swelling and itching appeared after injection, and with 10 mg/kg of HCO-60 there was additionally a decrease of spontaneous motility. In the two higher dose groups, these symptoms paralleled an increase of histamine levels. Since degranulation was observed after injection in the mast cells of the skin, but not in the liver of dogs, the histamine in the plasma was considered to be released from the mast cells of the skin. Pretreatment with diphenhydramine, a H1-receptor antagonist, suppressed the decrease of blood pressure induced by HCO-60. These findings show that the toxicity of HCO-60 is associated with histamine release from the mast cells. No symptoms occurred in monkeys, rabbits, guinea pigs or rats with 50 or 100 mg/kg of i.v. of HCO-60, and there was no change in plasma histamine levels. This study demonstrated that the toxicity of HCO-60 is species specific to dogs among the animals tested.
A 77GHz 4-Element Phased Array Receiver with On-Chip Dipole Antennas in Silicon (2006)

On-chip antennas are used in a fully integrated phased-array receiver at 77GHz. The complete down-conversion, power-combining, and phase-generation functions are integrated in silicon with no external mm-wave electrical connections. Each of the 4 receiver elements has 41dB of gain with a NF of 8dB with a system BW of 3GHz
Gene-modified T cells for adoptive immunotherapy of renal cell cancer maintain transgene-specific immune functions in vivo (2007)

ScFv(G250)-receptor-mediated functions of the scFv(G250)(+) T lymphocytes are, by and large, preserved in vivo upon administration, and may be reflected by fluctuations in plasma IFN-gamma levels.
An empirical analysis of the demand for commercial television advertising (1999)

The purpose of this paper is to provide an empirical analysis of the demand for commercial television advertising in the Sydney metropolitan market as a case study using unpublished quarterly data. Though the focus of the paper is empirical in nature, prior to this a simple oligopolistic framework is used to examine the influence of competition on TV advertising prices. Particular attention is paid to justifying the use of both short-and long-run time-series modelling techniques in order to derive respective short-and long-run price elasticities of demand. Results seem to suggest that the price elasticity of demand is robust in terms of theoretical expectation in sign and statistical significance, but substantially less than unity in the short run, and neighbouring unity in the long-run. These results seem to be consistent with the findings of Cave and Swann (Report of Committee on Financing the BBC, 1986) and Tavakoli, Swann and Cave (mimeo, Brunel University, 1989) for the British TV market, but differ from those of Hendry (Journal of Policy Modeling 14 (3), 1992) who estimated much larger elasticities for the same market. Without digressing into welfare implications, we also discuss what implications our results would have for the TV industry if policy initiatives likely to expand advertising supply on commercial TV were implemented.
Restructuring Databases for knowledge discovery by consolidation and link formation (1995)

Databases often inaccurately identify entities of interest. Two operations, consolidation and link formation, which complement the usual machine learning techniques that use similarity-based clustering to discover classifications, are proposed as essential components of KDD systems for certain applications. Consolidation relates identifiers present in a database to a set of real world entities (RWE’s) which are not uniquely identified the database. Consolidation may also be viewed as a transformation of representation from the identifiers present in the original database to the RWE’s. Link formation constructs structured relationships between consolidated RWE’s through identifiers and events explicitly represented in the database. An operational knowledge discover?, system which identifies potential money laundering in a database of large cash transactions implements consolidation and link formation. Consolidation and link formation are easily implemented as index creation in relational database management systems.