gebhart/patrepeval huggingface dataset:
Dielectric resonator antennas—a review and general design relations for resonant frequency and bandwidth (1994)

Abstract Open dielectric resonators (DRs) offer attractive features as antenna elements. These include their small size, mechanical simplicity, high radiation efficiency due to no inherent conductor loss, relatively large bandwidth, simple coupling schemes to nearly all commonly used transmission lines, and the advantage of obtaining different radiation characteristics using different modes of the resonator. In this article, we give a comprehensive review of the modes and the radiation characteristics of DRs of different shapes, such as cylindrical, cylindrical ring, spherical, and rectangular. Further, accurate closed form expressions are derived for the resonant frequencies, radiation Q‐factors, and the inside fields of a cylindrical DR. These design expressions are valid over a wide range of DR parameters. Finally, the techniques used to feed DR antennas are discussed. © 1994 John Wiley &amp; Sons, Inc.
Experimental and Biphasic FEM Determinations of the Material Properties and Hydraulic Permeability of the Meniscus in Tension1 (2002)

Tensile tests and biphasic finite element modeling were used to determine a set of transversely isotropic properties for the meniscus, including the hydraulic permeability coefficients and solid matrix properties. Stress-relaxation tests were conducted on planar samples of canine meniscus samples of different orientations, and the solid matrix properties were determined from equilibrium data. A 3-D linear biphasic and tranversely isotropic finite element model was developed to model the stress-relaxation behavior of the samples in tension, and optimization was used to determine the permeability coefficients, k1 and k2, governing fluid flow parallel and perpendicular to the collagen fibers, respectively. The collagen fibrillar orientation was observed to have an effect on the Young's moduli (E1=67.8 MPa, E2=11.1 MPa) and Poisson's ratios (v12=2.13, v21 =1.50, v23=1.02). However, a significant effect of anisotropy on permeability was not detected (k1 =0.09x10(-16) m4/Ns, k2=0.10x10(-16) m4/Ns). The low permeability values determined in this study provide insight into the extent of fluid pressurization in the meniscus and will impact modeling predictions of load support in the meniscus.
&lt;title&gt;Picture quality evaluation based on error segmentation&lt;/title&gt; (1994)

A segmentation-based error metric (SEM) is proposed to evaluate the quality of pictures with impairments resulting from typical source coding algorithms and channel interference. After appropriate visual preprocessing, the error picture is segmented into errors on own edges of the picture, errors representing exotic or spurious edges, and remaining errors in flat regions to describe edge errors like blurring, exotic structures like blocking and contouring, and residual errors like random noise, respectively. Error parameters or distortion factors are derived by appropriate summation over the segmented components. The distortion metric is built by a combination of the parameters using a generalized multiple linear regression procedure. Tests with a picture data base consisting of impairments from various picture coding techniques applied to different types of pictures have shown that the SEM yields very promising results. The correlation coefficient with subjective ratings was 0.875, whereas the widely used PSNR had only a correlation of 0.653. In addition, it is also possible to classify type and amount of individual distortions.
Alternate model for the cooperative equilibrium binding of myosin subfragment-1-nucleotide complex to actin-troponin-tropomyosin. (1983)

In this paper we introduce an alternate model for the equilibrium binding of S-l-N (S-l, subfragment l of myosin; N, nucleotide) on the troponin-tropomyosin-actin complex, including the influence of Ca2+ on this binding. In our previous model [Hill, T. L., Eisenberg, E. & Greene, L. E. (1980) Proc. Natl. Acad. Sci. USA 77, 3186-3190], we assumed that each tropomyosin unit, including one troponin-tropomyosin molecule and seven actin sites on the actin filament, could exist in two conformational states which presumably differed in the position of the tropomyosin on the actin. The binding of S-l-N or Ca2+ to the tropomyosin unit shifted the equilibrium between the two states but did not affect the intrinsic conformation of each state. In contrast, in the present model, we assume that tropomyosin can in principle occupy a continuum of positions on the actin filament. However, in any particular circumstance (N, Ca2+, salt, temperature), the tropomyosin occupies only a single position rather than existing in a dynamic equilibrium between two positions as in our earlier model. The binding of S-l-N or Ca2+ changes the position of tropomyosin on the actin filament and the exact position that the tropomyosin occupies depends on the nucleotide bound to S-l.
RAGE hydrocode modeling of asteroid mitigation: surface and subsurface explosions in porous PHO objects (2011)

Abstract Not Provided
Temperatures Measured in Human Cortical Bone when Drilling (1972)

Temperature measurements have been made in cortical bone while drilling under controlled laboratory conditions. Cortical temperatures greater than 100 degrees centigrade were frequently recorded when drilling if no specific provisions for cooling were made. The force applied to the drill was found to be much more important than drilling speed as a factor in both the magnitude and duration of cortical temperature elevations. Increases in the force applied to the drill were associated with decreases in the maximum temperatures and the durations of temperature elevation. Worn drills caused much greater temperature changes than new drills. All forms of irrigation that allowed the stream of irrigating fluid to be directed to the point of penetration of the cortex were effective in limiting the increases in cortical temperature. Tapping did not appear to cause significant temperature elevations.
Hybrid organosiloxane coatings containing epoxide precursors for protecting mild steel against corrosion in a saline medium (2016)

ABSTRACT Hybrid organic–inorganic materials made from sol–gel precursors can be used as anticorrosion barriers on metal substrates. The modification of epoxy resins with silicones is an interesting approach toward the synthesis of hybrid materials that combine the advantages offered by epoxy resins with those of silicones. In this study, novel hybrid epoxy‐silicon materials were synthesized using sol–gel chemistry and subsequently functionalized with 4,4′‐methylenebis(phenyl isocyanate), incorporating urethane functionality into the final polymer. The study screened five different epoxide precursors for use in the synthesis of the new hybrid materials and optimizing their anticorrosion properties. Spectral characterization confirms the proposed chemical structures of the newly synthesized polymers. The newly developed polymers were painted on mild steel panels, thermally cured, and their thermal, surface morphological, adhesion, and anticorrosion properties were fully characterized. The new coatings were found to have excellent thermal stability and adherence properties to steel surface. The results of corrosion testing on coated steel panels following long‐term immersion in a 3.5 wt % aqueous NaCl medium revealed that the polymer prepared using the epoxide precursor bisphenol A diglycidyl ether provided the best anticorrosion protection property among the synthesized polymers. This could be attributed to the excellent integrity and crosslink density properties in addition to the lack of microdefects in the surface of this coated sample as confirmed by scanning electron microscopy analyses. The newly prepared hybrid coatings reported in this study are very promising as an alternative to toxic chromate‐based coatings. © 2016 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2016 , 133 , 43947.
Q($λ$) with Off-Policy Corrections (2016)

We propose and analyze an alternate approach to off-policy multi-step temporal difference learning, in which off-policy returns are corrected with the current Q-function in terms of rewards, rather than with the target policy in terms of transition probabilities. We prove that such approximate corrections are sufficient for off-policy convergence both in policy evaluation and control, provided certain conditions. These conditions relate the distance between the target and behavior policies, the eligibility trace parameter and the discount factor, and formalize an underlying tradeoff in off-policy TD($λ$). We illustrate this theoretical relationship empirically on a continuous-state control task.
Off-track performance of thin film single pole head for perpendicular double-layered media (1998)

Side-fringing is an important factor for high track density recording. Track width written with a flying single pole flying head was measured through off-track profiles. The results show almost no side-fringing. The erase band width was around 25 nm for the off-track overwrite profile.
Pteridine, XXXI. Synthese und Eigenschaften blockierter 7.8‐Dihydro‐pterine (1966)

Abstract Mit der Synthese von 7.7‐Dimethyl‐7.8‐dihydro‐pterinen ( 38 – 40 ) wurden die ersten durch Alkylgruppen blockierten und somit gegen Oxydation stabilen Dihydropteridin‐Derivate dargestellt. Ihr auffallendstes Merkmal ist die starke bathochrome Verschiebung der langwelligen Absorptionsbande beim übergang vom Neutralmolekül zum Kation.
Multilevel imaging system realizing k1=0.3 lithography (1999)

The pursuit of ultimate resolution by optical lithography has given rise to many new technologies, such as PSM, oblique illumination etc. In order to realize the benefit of these new technologies in practice, a new exposure technology IDEAL is proposed. First exposure is for fine patterns, which are imaged with high contrast and large depth of focus, while second exposure is done with multileveled light distribution. These two exposures collaborate each other to form fine patterns with reasonable focus margin and good 2D profile. Experimental result of logic gate patterns are shown and demonstrate the possibility of k<SUB>1</SUB> equals 0.3 lithography. Using IDEAL, KrF lithography can be extended to 100-110 nm and ArF to 80 nm resolution.
Closure-aware sketch simplification (2015)

In this paper, we propose a novel approach to simplify sketch drawings. The core problem is how to group sketchy strokes meaningfully, and this depends on how humans understand the sketches. The existing methods mainly rely on thresholding low-level geometric properties among the strokes, such as proximity, continuity and parallelism. However, it is not uncommon to have strokes with equal geometric properties but different semantics. The lack of semantic analysis will lead to the inability in differentiating the above semantically different scenarios. In this paper, we point out that, due to the gestalt phenomenon of closure , the grouping of strokes is actually highly influenced by the interpretation of regions. On the other hand, the interpretation of regions is also influenced by the interpretation of strokes since regions are formed and depicted by strokes. This is actually a chicken-or-the-egg dilemma and we solve it by an iterative cyclic refinement approach. Once the formed stroke groups are stabilized, we can simplify the sketchy strokes by replacing each stroke group with a smooth curve. We evaluate our method on a wide range of different sketch styles and semantically meaningful simplification results can be obtained in all test cases.
Photoluminescence and Raman Scattering in Ag-doped ZnO Nanoparticles (2011)

Effects of Ag doping on the crystallinity and optical properties of zinc oxide (ZnO) nanoparticles have been studied by x-ray diffraction, diffuse reflectance spectroscopy, micro-Raman, and photoluminescence spectroscopy. It has been observed that while Ag-doping at low concentration improves the optoelectronic properties of ZnO nanostructures, Ag-doping at high concentrations drastically modify the emission behavior and lattice vibrational characteristics of the nanostructures. High Ag content in ZnO nanostructures causes lattice deformation, induces silent vibrational modes in Raman spectra, and reduces excitonic UV emission due to concentration quenching.
A Glial Cell Line-Derived Neurotrophic Factor-Secreting Clone of the Schwann Cell Line SCTM41 Enhances Survival and Fiber Outgrowth from Embryonic Nigral Neurons Grafted to the Striatum and to the Lesioned Substantia Nigra (1999)

We have developed a novel Schwann cell line, SCTM41, derived from postnatal sciatic nerve cultures and have stably transfected a clone with a rat glial cell line-derived neurotrophic factor (GDNF) construct. Coculture with this GDNF-secreting clone enhances in vitro survival and fiber growth of embryonic dopaminergic neurons. In the rat unilateral 6-OHDA lesion model of Parkinson's disease, we have therefore made cografts of these cells with embryonic day 14 ventral mesencephalic grafts and assayed for effects on dopaminergic cell survival and process outgrowth. We show that cografts of GDNF-secreting Schwann cell lines improve the survival of intrastriatal embryonic dopaminergic neuronal grafts and improve neurite outgrowth into the host neuropil but have no additional effect on amphetamine-induced rotation. We next looked to see whether bridge grafts of GDNF-secreting SCTM41 cells would promote the growth of axons to their striatal targets from dopaminergic neurons implanted orthotopically into the 6-OHDA-lesioned substantia nigra. We show that such bridge grafts increase the survival of implanted embryonic dopaminergic neurons and promote the growth of axons through the grafts to the striatum.
Infrared absorption of silicon irradiated by protons (1978)

Abstract Hydrogen implantations into silicon samples at room temperature and at 190°C are carried out. Infrared studies are performed on these samples before and following annealing. Previously observed divacancy and hydrogen vibrational bands are found as well as higher‐order‐bands not previously found in proton irradiation. In addition new hydrogen vibrational bands and other bands are observed and discussed.
A new approach to the synthesis of a protected 2-aminopurine derivative and its incorporation into oligodeoxynucleotides containing the Eco RI and Bam HI recognition sites (1988)

A protected 2-aminopurine nucleoside suitable for incorporation into oligodeoxynucleotides using phosphite triester chemical synthesis procedures has been prepared via oxidation of a purine hydrazino derivative with silver (I) oxide. Five oligodeoxynucleotides containing Eco RI and Bam HI recognition sites have been prepared such that, in the double stranded form, the 2-aminopurine base has either a complementary thymine or cytosine nucleobase. The helix character and thermodynamic parameters for helix formation have been examined.
Are We Really Close? Verifying Proximity in Wireless Systems (2017)

Current proximity verification and ranging systems are prone to distance modification attacks that can lead to loss of property or even human life. The authors survey the various approaches currently used to determine proximity and analyze their resilience against distance modification attacks. Drawing on these observations, they offer suggestions for design requirements that might help systems prove proximity with high-security guarantees.
Rescuing Mutant CFTR: A Multi-task Approach to a Better Outcome in Treating Cystic Fibrosis (2013)

Correcting multiple defects of mutant CFTR with small molecule compounds has been the goal of an increasing number of recent Cystic Fibrosis (CF) drug discovery programmes. However, the mechanism of action (MoA) by which these molecules restore mutant CFTR is still poorly understood, in particular of CFTR correctors, i.e., compounds rescuing to the cells surface the most prevalent mutant in CF patients--F508del-CFTR. However, there is increasing evidence that to fully restore the multiple defects associated with F508del-CFTR, different small molecules with distinct corrective properties may be required. Towards this goal, a better insight into MoA of correctors is needed and several constraints should be addressed. The methodological approaches to achieve this include: 1) testing the combined effect of compounds with that of other (non-pharmacological) rescuing strategies (e.g., revertants or low temperature); 2) assessing effects in multiple cellular models (non-epithelial vs epithelial, non-human vs human, immortalized vs primary cultures, polarized vs non polarized, cells vs tissues); 3) assessing compound effects on isolated CFTR domains (e.g., compound binding by surface plasmon resonance, assessing effects on domain folding and aggregation); and finally 4) assessing compounds specificity in rescuing different CFTR mutants and other mutant proteins. These topics are reviewed and discussed here so as to provide a state-of-the art review on how to combine multiple ways of rescuing mutant CFTR to the ultimate benefit of CF patients.
Photochemical Formation of Substituted Pentacenes (2008)

Substituted pentacenes (8a, 8b, 14a, and 14b) were prepared by Strating-Zwanenburg photodecarbonylation of diones (7a, 7b, 13a, and 13b). The compounds are red and stable in the solid state under inert atmosphere as well as in degassed solutions, but not in air. Each is soluble in common organic solvents where, unless protected, they are oxygen sensitive.
The role of immunotherapy in type I diabetes mellitus. (1987)

Type I diabetes mellitus appears to result from an insidious immunologic destruction of pancreatic beta-cells in genetically susceptible persons exposed to one or a series of environmental insults. This genetic susceptibility is related to alleles located on the sixth chromosome in the HLA-DR or an adjacent region. With superimposition of a viral or other environmental triggering event, cell-and antibody-mediated events are activated that lead to the specific autorejection of beta-cells and consequent insulin deficiency. Immunosuppressive strategies to impede or halt complete destruction of beta-cells, using cyclosporine, have already been initiated in both animals and humans with diabetes mellitus. Because of the potential toxicity of all current immunosuppressive regimens, such therapies cannot, at this time, be considered for wide-scale use in persons with type I diabetes. Reported inductions, however, of insulin independence in patients with newly diagnosed type I diabetes using cyclosporine or other agents underscore the role of the immune system in the pathogenesis of the disease and highlight the need to develop safer, more specific immunomodulation designed to avoid complete beta-cell destruction.
Industrial applications of electron accelerators (2006)

This paper addresses the industrial applications of electron accelerators for modifying the physical, chemical or biological properties of materials and commercial products by treatment with ionizing radiation. Many beneficial effects can be obtained with these methods, which are known as radiation processing. The earliest practical applications occurred during the 1950s, and the business of radiation processing has been expanding since that time. The most prevalent applications are the modification of many different plastic and rubber products and the sterilization of single-use medical devices. Emerging applications are the pasteurization and preservation of foods and the treatment of toxic industrial wastes. Industrial accelerators can now provide electron energies greater than 10 MeV and average beam powers as high as 700 kW. The availability of high-energy, high-power electron beams is stimulating interest in the use of X-rays (bremsstrahlung) as an alternative to gamma rays from radioactive nuclides.
Dynamically Controlled Thermal Flying-Height Control Slider (2008)

To achieve ultra-low flying height, magnetic spacing variations due to manufacturing tolerances and temperature-induced thermal protrusion need to be reduced. We have developed a thermal flying-height control (TFC) slider that carries a micro-thermal actuator. Previous TFC sliders were mainly statically controlled by a constant power supply. Our purpose is to demonstrate dynamic control of a TFC slider to compensate for high-speed magnetic signal modulation using feed-forward control methods. In this report, to dynamically compensate for magnetic signal modulation using TFC, two methods were examined. In method 1, TFC power was adjusted by using only time domain information. In Method 2, TFC power was adjusted by using frequency domain information in addition to time domain information. Method 2 showed better compensation for magnetic signal modulation due to better compensation at higher frequencies. These results showed that a dynamically controlled TFC slider is feasible in compensating for kilohertz order modulation.
Hydrophilic surface modification of polyethylene by NO-plasma treatment (1990)

The surface modification of polyethylene surfaces by NO-plasma irradiation was investigated from the point of view of the hydrophilicity and chemical composition. The hydrophilicity was evaluated from the advancing contact angle of water and the surface energy. The chemical composition of the modified surfaces was determined by diffuse reflectance Fourier transform infrared spectroscopy and XPS. NO-plasma irradiation for 5 min made the polyethylene surfaces hydrophilic. The advancing contact angle of water on the modified polyethylene surfaces reached 28 deg, and the surface energy was 57.6 mJ/m2. The incorporation of oxygen and nitrogen moieties on the polyethylene surfaces occurred during the NO-plasma irradiation. The main oxygen moieties were carbonyl groups, hydroxyl groups, and ether linkages; the nitrogen moieties were amino groups. NO-plasma irradiation was more effective in improving the hydrophilicity than the O2 plasma, N2 plasma, or corona discharge treatment.
CotA laccase: high-throughput manipulation and analysis of recombinant enzyme libraries expressed in <i>E. coli</i> using droplet-based microfluidics (2014)

We present a high-throughput droplet-based microfluidic analysis/screening platform for directed evolution of CotA laccase: droplet-based microfluidic modules were combined to develop an efficient system that allows cell detection and sorting based on the enzymatic activity. This platform was run on two different operating modes: the "analysis" mode allowing the analysis of the enzymatic activity in droplets at very high rates (>1000 Hz) and the "screening" mode allowing sorting of active droplets at 400 Hz. The screening mode was validated for the directed evolution of the cytoplasmic CotA laccase from B. subtilis, a potential interesting thermophilic cathodic catalyst for biofuel cells. Single E. coli cells expressing either the active CotA laccase (E. coli CotA) or an inactive frameshifted variant (E. coli ΔCotA) were compartmentalized in aqueous droplets containing expression medium. After cell growth and protein expression within the droplets, a fluorogenic substrate was "picoinjected" in each droplet. Fluorescence-activated droplet sorting was then used to sort the droplets containing the desired activity and the corresponding cells were then recultivated and identified using colorimetric assays. We demonstrated that E. coli CotA cells were enriched 191-fold from a 1 : 9 initial ratio of E. coli CotA to E. coli ΔCotA cells (or 437-fold from a 1 : 99 initial ratio) using a sorting rate of 400 droplets per s. This system allows screening of 10(6) cells in only 4 h, compared to 11 days for screening using microtitre plate-based systems. Besides this low error rate sorting mode, the system can also be used at higher throughputs in "enrichment" screening mode to make an initial purification of a library before further steps of selection. Analysis mode, without sorting, was used to rapidly quantify the activity of a CotA library constructed using error-prone PCR. This mode allows analysis of 10(6) cells in only 1.5 h.