gebhart/patrepeval huggingface dataset:
Application of an intelligent signal processing system to acoustic emission analysis (1989)

This article describes a novel approach for analyzing elastic wave signals to obtain a solution to simple inverse source problems. By using a simulated intelligent system that resembles the structure of a neural network and an acoustic source with its associated field of elastic waves in a plate, a set of pattern vectors is generated. The memory of the system is formed through a learning process in which a systematic series of experiments is presented to the system. In the experiments described here, the system was trained using simulated acoustic emission signals generated by a normal force acting on a thick plate to which information about the source related to its location and characteristics was appended. It is demonstrated, using such a trained system, that one can recover the characteristics of an unknown source from the acoustic signals emitted by it. It is also shown that one can synthesize from the memory the acoustic signals corresponding to an arbitrary source without using any elastodynamic theory.
Dual control of vascular tone and remodelling by ATP released from nerves and endothelial cells. (2008)

Purinergic signalling is important both in short-term control of vascular tone and in longer-term control of cell proliferation, migration and death involved in vascular remodelling. There is dual control of vascular tone by ATP released from perivascular nerves and by ATP released from endothelial cells in response to changes in blood flow (shear stress) and hypoxia. Both ATP and its breakdown product, adenosine, regulate smooth muscle and endothelial cell proliferation. The involvement of these regulatory mechanisms in pathological conditions, including hypertension, atherosclerosis, restenosis, diabetes and vascular pain, are discussed.
Design and Research of Students Integration System Based on SOA (2012)

Students integrated system is established by crossing business department, integrating the affairs flows, covering local business based on SOA, gets integrated management method model and solutions, and expounds the system is composed by students one-stop service center, student affairs, business supervision, comprehensive analysis and supporting platform component, then introduces the technical framework, popularizing and application effect of the system.
&lt;title&gt;3D imaging correlography and coherent image reconstruction&lt;/title&gt; (1999)

By illuminating an object with a laser and collecting far- field speckle intensity patterns, at a regularly spaced sequence of wavelengths, one obtains the squared magnitude of the 3D Fourier transform of the object. Performing 3D phase retrieval to reconstruct a 3D image (consisting of complex-valued voxels) is relatively difficult unless one has a tight support constraint. An alternative is to perform averaging of the autocovariance of the far-field speckle intensities, over an ensemble of speckle realizations, to estimate the square magnitude of the Fourier transform of the underlying (incoherent) reflectivity of the object, by the correlography method. This also gives us an incoherent- image-autocorrelation estimate, from which we can derive an initial support constraint. Since the image, being incoherent, is real-valued and nonnegative, performing phase retrieval on this data is easier and more robust. Unfortunately the resolution for correlography is only moderate since the SNR is low at the higher spatial frequencies. However, one can then use a thresholded version of that reconstructed incoherent image as a tight support constraint for performing phase retrieval on the original speckle intensity patterns to reconstruct a fine-resolution, coherent image. The fact that the objects are opaque plays an important role in the robustness of this approach. We will show successful reconstruction results from real data collected in the laboratory as part of the PROCLAIM (Phase Retrieval with an Opacity Constraint for LAser IMaging) effort.
Identification of Technetium-99m Binding Peptides Using Combinatorial Cellulose-Bound Peptide Libraries (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleIdentification of Technetium-99m Binding Peptides Using Combinatorial Cellulose-Bound Peptide LibrariesReinhard Malin, Renate Steinbrecher, Joerg Janssen, Wolfhard Semmler, Bernhard Noll, Bernd Johannsen, Cornelius Froemmel, Wolfgang Hoehne, and Jens Schneider-MergenerCite this: J. Am. Chem. Soc. 1995, 117, 47, 11821–11822Publication Date (Print):November 1, 1995Publication History Published online1 May 2002Published inissue 1 November 1995https://pubs.acs.org/doi/10.1021/ja00152a031https://doi.org/10.1021/ja00152a031research-articleACS PublicationsRequest reuse permissionsArticle Views105Altmetric-Citations40LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Non-intrusive built-in self-test for FPGA and MCM applications (2002)

Built-In Self-Test (BIST) techniques which are non-intrusive to the circuitry under test are investigated for incorporation in Field Programmable Gate Arrays (FPGAs) and Multi-Chip Modules (MCMs). The purpose is to test and diagnose circuitry external to the FPGAs or the various VLSI devices on MCMs during off-line system level testing. These approaches incur no area or performance penalties yet diagnostic resolution can be obtained to the device level. Design guidelines are developed to assist in the effective application and implementation of these techniques.
SmartTouch: electric skin to touch the untouchable (2004)

Augmented haptics lets users touch surface information of any modality. SmartTouch uses optical sensors to gather information and electrical stimulation to translate it into tactile display. Augmented reality is an engineer's approach to this dream. In AR, sensors capture artificial information from the world, and existing sensing channels display it. Hence, we virtually acquire the sensor's physical ability as our own. Augmented haptics, the result of applying AR to haptics, would allow a person to touch the untouchable. Our system, SmartTouch, uses a tactile display and a sensor. When the sensor contacts an object, an electrical stimulation translates the acquired information into a tactile sensation, such as a vibration or pressure, through the tactile display. Thus, an individual not only makes physical contact with an object, but also touches the surface information of any modality, even those that are typically untouchable.
A Review of Japanese Government Response to the Public Crises of Earthquakes (2014)

The disaster prevention plans and laws formulated by the Japanese government have successfully coped with the public crisis resulting from the Great East Japan (magnitude 9.0) earthquake. Meanwhile, the Japanese government took effective measures to cut losses, maintain social order, and organize the post-disaster reconstruction. However, some problems, such as delayed rescue, mishandling of nuclear leakage, and opaque information have been questioned by the public. This article will employ the theory of public management and public policy to review and analyze the above phenomena.
A new approach to pipeline FFT processor (2002)

A new VLSI architecture for a real-time pipeline FFT processor is proposed. A hardware-oriented radix-2/sup 2/ algorithm is derived by integrating a twiddle factor decomposition technique in the divide-and-conquer approach. The radix-2/sup 2/ algorithm has the same multiplicative complexity as the radix-4 algorithm, but retains the butterfly structure of the radix-2 algorithm. The single-path delay-feedback architecture is used to exploit the spatial regularity in the signal flow graph of the algorithm. For length-N DFT computation, the hardware requirement of the proposed architecture is minimal on both dominant components: log/sub 4/N-1 complexity multipliers and N-1 complexity data memory. The validity and efficiency of the architecture have been verified by simulation in the hardware description language VHDL.
High-affinity reactions between antigen-specific T-cell receptors and peptides associated with allogeneic and syngeneic major histocompatibility complex class I proteins. (1994)

We report here that the intrinsic affinities of the antigen-specific T-cell receptors (TCR) of two unrelated CD8+ T-cell clones for their respective peptide-major histocompatibility complex (MHC) ligands are higher than the values generally thought to prevail for TCR. The TCR of one clone (2C) binds an allogeneic class I MHC protein (Ld) in association with an alpha-ketoglutarate dehydrogenase nonapeptide (QLSPFPFDL, termed QL9) with an intrinsic affinity (intrinsic equilibrium association constant) of 1-2 x 10(7) M-1. The TCR of the other clone (4G3) binds a syngeneic class I MHC protein (Kb) in association with an ovalbumin octapeptide (SIINFEKL, termed pOV8) with an intrinsic affinity of 1.5 x 10(6) M-1. A comparison of the two clones, combined with current views of T-cell repertoire selection in the thymus, leads us to propose that TCR affinities are generally likely to be higher for allogeneic MHC-peptide complexes than for syngeneic MHC-peptide complexes.
Effects of clozapine on cognitive function in schizophrenia. (1994)

Cognitive dysfunction may underlie some of the psychopathology of schizophrenia as well as contribute to impaired social and vocational function in this disorder. Chronic treatment with typical neuroleptics has been reported to produce only minimal improvement in and may impair cognitive function in schizophrenia. We have studied the effect of clozapine, an atypical antipsychotic drug, on cognitive function in 36 patients with treatment-resistant schizophrenia. In addition, patients with non-treatment-resistant schizophrenia were randomly assigned to clozapine (N = 24) or typical neuroleptics (N = 23). Cognitive function in the treatment-resistant schizophrenia group was studied after 6 weeks and 6 months of treatment, while the non-treatment-resistant patients were also studied at 12 months of treatment. Clozapine treatment improved several domains of cognitive function, especially attention and verbal fluency in both treatment-resistant schizophrenia and non-treatment-resistant schizophrenia. On the other hand, typical neuroleptic treatment produced minimal improvement in cognitive function. The effect of clozapine on some tests of attention and verbal fluency was significantly greater than that of typical neuroleptic treatment in non-treatment-resistant schizophrenia. These data suggest that clozapine treatment was superior to typical neuroleptics in improving cognitive function in schizophrenia. The possibility that this is related to normalization of dopaminergic function by clozapine is discussed.
An Efficient Fully Implicit Simulator (1980)

Abstract This paper describes PORES, an efficient general purpose implicit three-phase three-dimensional black oil reservoir simulator. Efficiency is achieved by solving the coupled equations using a new sequential method which automatically ensures material balance. A new iterative method for the solution of the linear equations is described. This method also conserves material and uses a truncated conjugate gradient technique to accelerate convergence. Simultaneous and direct solution options are also provided. PORES contains an extensive well model which is numerically stable, meets production targets precisely, and apportions flows accurately to individual layers of the reservoir model. Other practical features include a numerical aquifer model, flexible pseudo function facilities, and a two-point upstream option for the control of numerical dispersion. Two examples are presented to illustrate the use of the fully-implicit sequential method.
CD200 Expression on Tumor Cells Suppresses Antitumor Immunity: New Approaches to Cancer Immunotherapy (2007)

Although the immune system is capable of mounting a response against many cancers, that response is insufficient for tumor eradication in most patients due to factors in the tumor microenvironment that defeat tumor immunity. We previously identified the immune-suppressive molecule CD200 as up-regulated on primary B cell chronic lymphocytic leukemia (B-CLL) cells and demonstrated negative immune regulation by B-CLL and other tumor cells overexpressing CD200 in vitro. In this study we developed a novel animal model that incorporates human immune cells and human tumor cells to address the effects of CD200 overexpression on tumor cells in vivo and to assess the effect of targeting Abs in the presence of human immune cells. Although human mononuclear cells prevented tumor growth when tumor cells did not express CD200, tumor-expressed CD200 inhibited the ability of lymphocytes to eradicate tumor cells. Anti-CD200 Ab administration to mice bearing CD200-expressing tumors resulted in nearly complete tumor growth inhibition even in the context of established receptor-ligand interactions. Evaluation of an anti-CD200 Ab with abrogated effector function provided evidence that blocking of the receptor-ligand interaction was sufficient for control of CD200-mediated immune modulation and tumor growth inhibition in this model. Our data indicate that CD200 expression by tumor cells suppresses antitumor responses and suggest that anti-CD200 treatment might be therapeutically beneficial for treating CD200-expressing cancers.
Radiation hardened micron and submicron MOSFETs containing fluorinated oxides (1989)

The generation of interface traps and oxide trapped charge in fluorinated MOSFETs and MOS capacitors has been found to depend strongly on the amount of fluorine introduced. In this study, the fluorine is introduced by low-energy F implantation into the surface layer of the polycrystalline silicon gate electrode, followed by annealing at 950 degrees C to diffuse F into the gate SiO/sub 2/, toward the SiO/sub 2//Si interface The improved interface radiation hardness is attributed to the strain relaxation near the SiO/sub 2//Si interface due to fluorine incorporation. An optimum F implant dose has been found to exist for a given technology; in the present case the optimum dose appears to be 2*10/sup 15/ cm/sup -2/. The results demonstrate the potential of the technique for producing radiation hard micron and submicron MOS devices.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Evaluation of Naf Formulations, Dursban Pro, and Scimitar Cs for Management of Black Cutworm on Creeping Bentgrass, 1995 (1997)

Abstract Treatment plots were 10 X 8 ft, arranged in a RCB design and replicated 4 times at University Park, PA. Liquid formulations were applied by using a CO2 compressed air sprayer with 6 8002VS TeeJet nozzles mounted on an 8 ft boom, operating at 28 psi, and applied in 350 ml of water/80 ft2 or delivering 1.1 gal/1,000 ft2. Treatments were made on 31 Jul when black cutworm feeding damage was first observed on close cut bentgrass. An average of 5.0/yd2 cutworm larvae was recorded on 31 Jul prior to treatment. At treatment time (31 Jul), the following soil and environment conditions existed: air temperature, 74°F; soil temperature at 1 inch depth, 82°F; soil temperature at 2 inch depth, 72°F; RH, 68%; amount oJ thatch, 0.125-0.25 inch; soil textural class, sandy loam; soil particle size analysis: 52.8% sand, 35.2% silt, 12.0% clay; soil moisture (oven dry weight). 31.3%; organic matter, 3.3%; water pH, 7.0; soil pH, 6.6; time of application, early morning; and clear skies. The area received 0.1 inch of irrigation immediately after treatment. Evaluation was done on three sampling dates (3 Aug, 7 Aug, 15 Aug) by counting the number of black cutworm larvae flushed to the surface within a 1.0 yd2 wood frame sampling area using a soap irritant drench of 15 ml Lemon Joy™ dishwashing detergent in 2 gal of water. Extremely high temperatures reduced natural occurring black cutworm populations. All treatments on the last two of the 3 sampling dates provided significant reduction of black cutworm larvae relative to untreated check. No phytotoxicity was noted.
[Characteristics of the mutagenic and toxic effects of ethylene imine and its oligomers. Comparative study in the automated SOS-chromotest system and in standard bacterial test systems]. (1988)

Raising total positive charge of a chemical mutagen does increase its local concentration in the area of biological target-DNA, and, as a consequence, causes increase in the rate of interaction of a mutagen with the target. Experimental evidence of this idea has been obtained in three test systems: the Ames test, Trp+ reversions in Escherichia coli WP2 and in the automated "SOS-chromotest" system with E. coli PQ 37 ("Labsystems", Finland).
Plant Communication from Biosemiotic Perspective (2006)

As in all organisms, the evolution, development and growth of plants depends on the success of complex communication processes. These communication processes are primarily sign mediated interactions and not simply an exchange of information. They involve active coordination and active organization-conveyed by signs. A wide range of chemical substances and physical influences serve as signs.Different abiotic or biotic influences require different behaviors. Depending on the behavior, the core set of signs common to species, families, genera and organismic kingdoms is variously produced, combined and transported. This allows entirely different communication processes to be carried out with the same types of chemical molecules.Almost without exception, plant communication are parallel processes on multiple levels, (A) between plants and microorganisms, fungi, insects and other animals, (B) between different plant species as well as between members of the same plant species; (C), between cells and in cells of the plant organism.
Transistor sine-wave<i>LC</i>oscillators. Some general considerations and new developments (1959)

The paper begins by showing that various well-known simple oscillator circuits, usually analysed separately, are essentially equivalent to one another if certain reasonable assumptions are made, and appreciation of this fact simplifies the design problem.A discussion follows concerning class-C oscillators and the difficulty of combining high efficiency with a satisfactory degree of independence of transistor parameters. The problem of avoiding squegging is also considered.A simple push-pull high-efficiency oscillator is then described, in which substantially constant current flows in each transistor for the whole of its 180° conduction angle. This oscillator is believed to possess a unique combination of desirable features.Another unusual high-efficiency oscillator is then presented, which is more elaborate than the previous one but which has advantages in certain respects.The paper ends with a description of an oscillator based on the ‘long-tailed-pair’ circuit. The oscillator is exceptionally easy to design and make, and is suitable for applications where high efficiency is not important. It can supply either a sine wave or a square wave, or both.
Neutral catecholate derivatives of manganese and iron: synthesis and characterization of the metal-oxygen cubane-like species M4(DBCat)4(py)6 (M = Mn, Fe), the trinuclear complex Mn3(DBCat)4(py)4, and the dimers M2(DBCat)2(py)n (M = Mn, n = 6; M = Fe, n = 4,6) (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNeutral catecholate derivatives of manganese and iron: synthesis and characterization of the metal-oxygen cubane-like species M4(DBCat)4(py)6 (M = Mn, Fe), the trinuclear complex Mn3(DBCat)4(py)4, and the dimers M2(DBCat)2(py)n (M = Mn, n = 6; M = Fe, n = 4,6)Steven C. Shoner and Philip P. PowerCite this: Inorg. Chem. 1992, 31, 6, 1001–1010Publication Date (Print):March 1, 1992Publication History Published online1 May 2002Published inissue 1 March 1992https://pubs.acs.org/doi/10.1021/ic00032a016https://doi.org/10.1021/ic00032a016research-articleACS PublicationsRequest reuse permissionsArticle Views459Altmetric-Citations51LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Single Ion Channel Recordings with CMOS-Anchored Lipid Membranes (2013)

We present single-ion-channel recordings performed with biomimetic lipid membranes which are directly attached to the surface of a complementary metal-oxide-semiconductor (CMOS) preamplifier chip. With this system we resolve single-channel currents from several types of bacterial ion channels, including fluctuations of a single alamethicin channel at a bandwidth of 1 MHz which represent the fastest single-ion-channel recordings reported to date. The platform is also used for high-resolution α-hemolysin nanopore recordings. These results illustrate the high signal fidelity, fine temporal resolution, small geometry, and multiplexed integration which can be achieved by leveraging integrated semiconductor platforms for advanced ion channel interfaces.
The c-Abl inhibitor, Nilotinib, protects dopaminergic neurons in a preclinical animal model of Parkinson's disease (2014)

c-Abl is activated in the brain of Parkinson's disease (PD) patients and in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-intoxicated mice where it inhibits parkin through tyrosine phosphorylation leading to the accumulation of parkin substrates, and neuronal cell death. In the present study, we evaluated the in vivo efficacy of nilotinib, a brain penetrant c-Abl inhibitor, in the acute MPTP-induced model of PD. Our results show that administration of nilotinib reduces c-Abl activation and the levels of the parkin substrate, PARIS, resulting in prevention of dopamine (DA) neuron loss and behavioral deficits following MPTP intoxication. On the other hand, we observe no reduction in the tyrosine phosphorylation of parkin and the parkin substrate, AIMP2 suggesting that the protective effect of nilotinib may, in part, be parkin-independent or to the pharmacodynamics properties of nilotinib. This study provides a strong rationale for testing other brain permeable c-Abl inhibitors as potential therapeutic agents for the treatment of PD.