Approach for clear versioning: The date (format: "dd_mm_yyyy") and the
initials of the last person modifying the document (each researcher or staff
involved has a identifyer code in the project of 2 or 3 capital letters) are
added after the name of the modified file. If more than one version of the
same document/author is generated same day "v2, v3, v4..." is added after
date. Documents can be locked for access in Drive, so two versions are not
generated simultaneously by different authors. All older versions are kept in
Google-Drive, at least until the final version is generated.

Standards for metadata creation (if any). If there are no standards in your
discipline describe what metadata will be created and how (pending task, see
above)

2.2 Making data openly accessible:

#  ALL POINTS MUST BE REFINED/COMPLETED. INPUT FROM ALL INSTITUTIONS REQUIRED

Patentable and sensitive (IP at risk) data protection will be responsibility
for the IP owners. These data, as well as publishable but not patentable data,
will be protected and can be safely kept in 3D-NEONET folders with restricted
access. Open access (green and gold) Journals and media will be always chosend
in first place for publication. Copies of non-open acess 3D-NEONET articles
(if any) will be kept in UCD Library repositories to enable availability to
the research commnity and the society in general. All multimedia and videos,
as well as management guidelines and tools for clinical trials, generated in
3D-NEONET will be openly accesible in internet (through you tube, Vimeo,
Slide-Share and 3D-NEONET webside).

How the data will be made available: Publications, Internet (Pending task)

Methods and software tools are needed to access the data (Pending task)

Where the data and associated metadata, documentation and code are deposited
(Pending task/described elsewhere in this DMP)

How access will be provided in case there are any restrictions (Pending
task/described in other sections. Different access-levels granted through
google Drive)

2.3 Making data interoperable:

#  ALL POINTS MUST BE REFINED/COMPLETED. INPUT FROM ALL INSTITUTIONS REQUIRED

Interoperability of your data. Data and metadata vocabularies yet to be agreed
in the consortium. In principle, no data sets that require the development of
novel specific standards and methodologies to facilitate interoperability will
be generated in the project. All datasets generated are expected to map to
commonly used ontologies.

3D-NEONET will be using standard vocabulary for all data types present in the
project data assets, to allow inter-disciplinary interoperability.

2.4 Increase data re-use (through clarifying licenses):

#  ALL POINTS MUST BE REFINED/COMPLETED. INPUT FROM ALL INSTITUTIONS REQUIRED

3D-NEONET data will be licenced to permit the widest reuse possible (Pending
task: elaborate and describe how)

When the data will be made available for re-use (If applicable: why and for
what period a data embargo is needed (Pending task: to be discussed/agreed
within the consortium)

Is the data produced and/or used in the project useable by third parties, in
particular after the end of the project? If the re-use of some data is
restricted, explain why (Pending task: to be discussed/agreed within the
consortium)

Data quality assurance processes. Internal review by steering committee,
external review by scientific&medical advisory board,

Peer review for publication and patenting (Pending task: A SOP for Data
quality assurance must be oulined for 3D-NEONET)

Length of time for which the data will remain re-usable: So far, ther is not
any envisaged deadline for 3D-NEONET data re-use availability.

##  3\. ALLOCATION OF RESOURCES

There was no specific budget allocation to data manegement/FAIR in the
original proposal. We estimate that overall costs per researcher/month of
exchange to make 3D-NEONET fair will be roughly: a) €100/researcher-month
(split among sending, host and coordinator institution), plus b)10% time of
the seconded fellow, plus c) 5% time of the project manager, plus 1% time of
the Data Management Boards Members. Economic costs will come from the
"management and indirect costs" budget of each research unit. Project
management in general (including data management) will be overseen by the
Steering Board comprising of a Scientist in Charge from each partner, and the
dedicated Project Manager, working 2 hrs/day on this project. Both sending and
host institutions will be responsible for safe storage and appropiate sharing
(in line with GA, CA, MTA and IP agreements in force) of the data generated by
exchanged fellows. There will be also a Data-Management Board, composed by one
representative researcher from each 3D-NEONET institution and chaired by the
Project Coordinator/Project Manager, that will closely monitor data-management
in the consortium, ensuring implementation of best practices. The Data
Management Board will follow-up with fellows in relation to data generated
during their exchanges. Fellows will be responsible for completing the
required information in the Fellows-Research-Data table described in section 1
(Data Summary) of this document. The Data Management Board will report to the
Seering Board at general meetings and TCs. This board will be responsible for
periodic reviwes and updates (at least every 6 months) of this Data Management
Plan.

3DNEONET Steering Board will be the ultimate responsible for safe storing and
overall redistributing of all raw & processed data generated in the
consortium, ensuring its preservation and accesibility to the research
community beyond the lifetime of this project. Long term preservation and
accesibility to data generated in this project are crucial as they may lead to
the discovery or development of novel therapeutics for cancer or severe eye
disease in future. These will be ensured by (green and gold) Open Access
publication of papers (research articles and reviews), combined with patent
protection of exploitable results. Raw data will be kept in available
repositories at each institution. Raw an processed data can be also safely and
long term stored in the 3D-NEONET Google Drive Collaborative of unlimited
capacity, which is owned and provided free of charge to the consortium by the
coordinator University (UCD).

##  4\. DATA SECURITY

The coordinator and project managerensure appropriate and fluent communication
between partners/researchers, facilitating secure shared filing repositories
(Google Drive storage available at UCD).

The 3D-NEONET Google Drive Collaborative of unlimited capacity provided by the
coordinator (UCD), is an online storage service that allows users to upload,
create, share, and work collaboratively with others on a variety of documents
online. Files uploaded to Google Drive, are stored in secure data centers.  
  
<table>  
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<th>

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</th>  
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If hardware/local drive breaks (computer lost or broken) files can still be
accessed from other registered devices and from the cloud-server, as well as
access by other users.

</th> </tr>  
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<td>



</td>  
<td>

Files deleted by mistake can be recovered from the recycle bin

</td> </tr>  
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<td>



</td>  
<td>

Files are private unless shared. Access to files and directories is restricted
to the coordinator and project manager by default, who control permits granted
to different users (to access, use and share the data).

</td> </tr> </table>

As an additional safety and recovery meassure, we have in the consortium two
mirror copies of the 3D-NEONET collaborative folder were all data is stored.
These are automatically synchronised and one of them is only accesible by the
coordinator and the project manager. The second mirror copy is accessible by
the whole steering committee (including coordinator, project manager and WP-
leaders/scientists in charge at each institution). Fellows (an other member of
the consortium) are given view/donwload access to certain files subject to
specific requirements of the project.

Finally there is Public-3D-NEONET folder with Open view/download Access were
non-IP sensitive files are shared within and beyond the consortium.

##  5\. ETHICAL ASPECTS

3D-NEONET project complies with ethical principles (including the highest
standards of research integrity, as set out, for instance, in the European
Code of Conduct for Research Integrity and including, in particular, avoiding
fabrication, falsification, plagiarism or other research misconduct)

All 3D-NEONET partners are sensitive to the appropriate ethical use of animals
for scientific research and the project will be carried out with maximum
respect to all fundamental ethical principles, including those reflected in
the Charter of Fundamental Rights of the European Union. The use of animals
will be restricted to cases of absolute necessity, where in vitro or ex vivo
experimentation are not valid to address certain aspects of the science
programme. Also, human biological samples (ex vivo explants tissue) from
cancer patients will be used for some experiments. All tissues collected will
be consented for use by the patients attending clinic

The following documentation will be submitted to the coordinator before any
experimentation linked to ethical implications is carried out: 1) copies of
ethics approvals for the research with humans; 2) copies of relevant
authorisations (for breeders, suppliers, users, and facilities) for animal
experiments using genetically modified vertebrates (Zebrafish, Mice, Rabbits);
3) If applicable, the copies of opinion or confirmation by the competent
Institutional Data Protection Officer and/or authorization or notification by
the National Data Protection Authority (which ever applies according to the
Data Protection Directive (EC Directive 95/46, currently under revision, and
the national law). In addition, copies of training certificates/personal
licenses of the staff involved in animal experiments will be provided before
they start their secondments. All the documentation described above will be
safely stored in the 3D-NEONET Google Drive Collaborative folder.

All the experiments undertaken in this project will be carried out in
conformity with EU legislation. All regulations comply with European ethic
guidelines for use of animals and human tissue for research purposes. Full
details on normatives, licences, protocols and technical aspects related to
the project ethics, can be found in the Annex 1 to the Grant Agreement
(Description of the Action), Part B.

##  6\. OTHER

The coordinator Institution (UCD) has a Research Data Management Unit based in
the UCD Library that assist researchers at all different stages of the
research data lifecycle, from funding requirements to data capture and
processing tosharing, storage and preservation. They have published a
comprehensive website on all aspects of Research Data Management
(http://libguides.ucd.ie/data)

UCD IT Services provide the additional following information and support on
data management: Data Classification Guidance, Data Storage (Google Drive) and
IT security.