Manhattan plots for the GWAS results for the skin (A), hair (B), and eye (C) pigmentation. The log-transformed p-values from the test of association are plotted as a function of the chromosomal position. Genome-wide significance is defined as the Bonferroni corrected 5% significance threshold (p-value<1.6×10−7) and is indicated as a red line. For skin pigmentation, one SNP on chromosome 3 in the FLNB gene almost reaches genome-wide significance (p-value = 1.8×10−7). No SNP achieves genome-wide significance in the hair pigmentation GWAS. For eye pigmentation, two SNPs, one near the pigmentation gene OCA2 on chromosome 15 and one in the SCIN gene on chromosome 7 achieve genome-wide significance