Biohybrid device controlled by electronic signals - The biohybrid device receives both chemical and electronic inputs, and through biochemical intermediates, translates them to both electrochemical signals and biological cell responses. A representation of the components of the multi-domain fusion protein is shown in the enlarged box. By varying the electronic inputs through the electrodes on which HLPT is attached, they can vary the attenuation of HLPT activity and thus affect the electrochemical and biological responses in proportion to the input.