Transmission electron micrograph of chicken ileum, 18-hr after experimental infection with human Salmonella (3,10:r:-) organisms. Microbes (Sal) release bacterial outer membrane vesicles (OMVs) of 80-90 nm diameter size, seen docking on host microvillous membrane, and implicated in signaling host cell cytoplasmic reorganization after focally disrupting microvilli and creating 'corridor' passage (for microbe entry, thick arrow) from a ruffled surface.