FIGURE 1: Statistical parametric mapping (SPM) showing clusters in the left pregenual anterior cingulate cortex and the right ventral premotor cortex. There are significant differences in gray matter volume between the PTSD and control groups. doi:10.1371/journal.pone.0042560.g001 Conclusion: Volume reduction in the premotor cortex that is observed in victims of urban violence with PTSD may be associated with a disruption in the dynamical modulation of the safe space around the body. The finding that PTSD patients presented a smaller volume of pregenual anterior cingulate cortex is consistent with the results of other PTSD neuroimaging studies that investigated different types of traumatic events.