Original sentence: Callen openly denied the HIV theory of AIDS and was especially critical of AZT monotherapy when it was first introduced: "The HIV paradigm has produced nothing of value for my life and I actually believe that treatments based on the arrogant belief that HIV has proven to be the sole and sufficient cause of AIDS has hastened the deaths of many of my friends
Edited sentence: Callen was openly doubtful of the HIV theory of AIDS and especially critical of AZT monotherapy when it was first introduced: "The HIV paradigm has produced nothing of value for my life and I actually believe that treatments based on the arrogant belief that HIV has proven to be the sole and sufficient cause of AIDS has hastened the deaths of many of my friends