Original sentence: Due to the inhibition of the CYP-450 enzyme, THC, the psychoactive substance in Cannabis, would not be able to be metabolized until the inhibition of the CYP-450 enzyme is lifted, which may take hours, thus increasing the duration of it's effect
Edited sentence: Due to the inhibition of the CYP-450 enzyme, THC, the psychoactive substance in Cannabis, would not be able to be metabolized until the inhibition of the CYP-450 enzyme is lifted, which may take hours, thus increasing the duration of the narcotic effect