Original sentence: As of early 2007, the COURAGE clinical trial  , reported during the ACC convention, which compared "optimal medical therapy" with or without additional angioplasty +/- stents, demonstrated that angioplasty +/- stents did not improve survival over "optimal medical therapy".The success of "optimizing" lipoprotein levels, not just to low adult but to at or near childhood levels, before the typical onset of atheromas, the key lesion of atherosclerosis, is one of the most effective results of "optimal medical therapy"