Original sentence: It is believed that the in vivo capabilities require levels as high as 10 ppm F, which only last for brief periods with orally applied topical fluoride Evidence does point to many direct and indirect effects on bacterial cells by fluoride.There have been large amounts of investigation and papers written on the antimicrobial effects of fluoride on oral micro flora, but there exists no consensus on the effects of fluoride on oral bacteria
Edited sentence: Fluoride's effect on oral microflora does not play an important role in fluoride's effectiveness against cavities