Original sentence: A match is achieved by; matching as a unit, one stem of some length with another of some length in such a way that the two must be connected by canonical base pairs – loops are added to the grammar as appropriate.Purely grammatical context-sensitive method exists: The structural configuration of pseudoknots does not lend itself well to bio-computational detection due to its context-sensitivity or “overlapping” nature.The grammatical method essentially ignores rna molecular energy and “looks for” or matches a specific configuration which can then be further verified via slower and more computationally expensive methods.Thus, popular programs like Mfold or biological sequence search engines such as BLAST cannot predict them
Edited sentence: A candidate configuration is found by matching, as a unit, one stem of some length with another stem of some length in such a way that the two must be connected by canonical base pairs.A purely grammatical context-sensitive method takes a different approach, essentially ignoring RNA molecular energy and searching for specific configurations which can then be further verified via slower and more computationally expensive methods.Loops are added to the grammar as appropriate.The structural configuration of pseudoknots does not lend itself well to bio-computational detection due to its context-sensitivity or “overlapping” nature.Thus, popular programs like Mfold and biological sequence search engines such as BLAST cannot predict them