Original sentence: Studies of both treatment methodologies have in general not yielded definitive evidence of efficacy when framed in terms of long-term prevention of problem drinking, although limitations are widely acknowledged in obtaining acceptable data due to the impossibility of applying adequate controls to clinical analysis of AA
Edited sentence: Studies of both treatment methodologies have in general not yielded definitive evidence of efficacy, although limitations are widely acknowledged in obtaining acceptable data due to the impossibility of applying adequate controls to clinical analysis of AA