Original sentence: As with many diseases with diffuse symptoms, there is controversy, among physicians, if RLS is a distinct syndrome.Other clinicians associate it with lumbosacral spinal subluxations and life stress.Some physicians doubt that RLS actually exists as a legitimate clinical entity, but believe it to be a kind of "catch-all" category, perhaps related to a general heightened sympathetic nervous system (SNS) response that could be caused by any number of physical or emotional factors.The US National Institute of Neurological Diseases and Stroke publishes an information sheet  characterizing the syndrome but acknowledging it is a difficult diagnosis
Edited sentence: Incidentally, the side effects of some Restless Leg Syndrome drugs can be very serious.Lumbosacral spinal subluxations and life stress are two of these.Many physicians doubt that RLS actually exists as a legitimate clinical entity, but believe it to be a kind of "catch-all" category...perhaps related to a general heightened sympathetic nervous system (SNS) response that could be caused by any number of physical or emotional factors.This must be considered by anyone seeking a medical solution for RLS