Edited sentence: 240, 407-415, 1994).52, 1519-1524, 2004; N Marty, J.Clinical Investigation vol, 115, 3545, 2005).Gomori-positive astrocytes.Gomori-positive astrocytes are much more abundant within the arcuate nucleus of the hypothalamus and in the hippocampus than in other brain regions.Histochemistry & Cytochemistry vol.It is now know that these granules are formed from the remnants of degenerating mitochondria engulfed within lysosomes (JR Brawer, Anatomical Record vol.Some type of oxidative stress appears to be responsible for the mitochondrial damage within these specialized astrocytes.These are a subset of protoplasmic astrocytes that contain numerous cytoplasmic inclusions, or granules, that stain positively with Gomori's chrome-alum hematoxylin stain.They may have a role in regulating the response of the hypothalamus to glucose (JK Young, J