Original sentence: In accordance with these definitions, the three largest population centers in the Americas are: Mexico City, the largest metropolitan area in the Americas; New York City, the largest urban area in the Americas; and São Paulo, the largest city proper in the Americas
Edited sentence: In accordance with these definitions, the three largest population centers in the Americas are: Mexico City, anchor to the largest metropolitan area in the Americas; New York City, anchor to the largest urban area in the Americas; and São Paulo, the largest city proper in the Americas