Original sentence: According to National Institute for Health and Clinical Excellence, benzodiazepines can be used in immediate management of generalized anxiety disorder (GAD), if necessary
Edited sentence: According to National Institute for Health and Clinical Excellence, benzodiazepines can be used in the immediate management of generalized anxiety disorder (GAD), if necessary.Furthermore, evidence suggests that after 4-6 weeks the effect of benzodiazepines may decrease to the level of placebo.Generally, benzodiazepines are less effective than antidepressants in alleviating ruminative worry, the core symptom of GAD.In this light, CPA notes that, although benzodiazepines can be used any time for severe anxiety and agitation, such use should be, ideally, short-term.Nevertheless, some patients may require prolonged treatment with benzodiazepines as the add-on to an antidepressant.Similarly, Canadian Psychiatric Association (CPA) recommends benzodiazepines alprazolam, bromazepam, lorazepam, and diazepam only as a second-line choice, if the treatment with two different antidepressants was unsuccessful