Original sentence: It is difficult to study because it is both unstable and poorly bioavailable.Laboratory and clinical research have not confirmed any medical use for curcumin.The US government has supported US$150 million in research into curcumin through the National Center for Complementary and Integrative Health, and no support has been found for curcumin as a medical treatment
Edited sentence: It is difficult to study because it is both unstable and poorly bioavailable, yet its bioavailability is greatly improved when combined with other digestive compounds like piperine (the active compound of black pepper).Laboratory and clinical research have not confirmed any medical use for curcumin, however there are thousands of papers showing potential anti-inflammatory health benefits in various in vitro, in vivo and randomized clinical trials.Studies support its use as an antioxidant, anti-inflammatory agent, to improve digestion, protect liver function, decrease pain symptoms, increase BDNF in the brain and protect against neurological decline, reduce symptoms of depression, lower various inflammatory cytokines such as IL-6, TNF-a, and may exhibit anti-cancer and anti-inflammatory effects on the GI track for conditions such as colorectal cancer and ulcerative colitis.The US government has supported US$150 million in research into curcumin through the National Center for Complementary and Integrative Health, and mixed results have been found for curcumin regarding its health benefits, it likely needs to be taken with other digestive compounds such as boswellia or piperine (the active compound of black pepper) to reach a meaningful bioavailability