Original sentence: Other highly disputed studies indicate a variety of negative effects associated with constant, long-term use, including memory loss, depression and loss of motivation, though anecdotal evidence gives a very different picture.The long-term effects of THC on humans is highly disputed, and the issue is highly politicized because of its status as an illegal drug
Edited sentence: Other studies indicate a variety of negative effects associated with constant, long-term use, including memory loss, depression and loss of motivation.The long-term effects of THC on humans is highly disputed, and the issue is politicized because of its status in the United States as a schedule I drug, according to the Controlled Substances Act (other tetrahydrocannibinol analogues such as Δ6-tetrahydrocannabinol are also listed in the Controlled Substances Act