fenil210/Med-Lamma huggingface dataset:
What is (are) High Blood Cholesterol ?
If TLC (Therapeutic Lifestyle Changes) cannot lower your LDL cholesterol level enough by itself, your doctor may prescribe cholesterol-lowering medicines. The following medicines are used together with TLC to help lower your LDL (bad) cholesterol level. - statins  - ezetimibe  - bile acid sequestrants  - nicotinic acid  - fibrates. statins ezetimibe bile acid sequestrants nicotinic acid fibrates. Statins  - are very effective in lowering LDL (bad) cholesterol levels   - are safe for most people  - have side effects that are infrequent, but potentially serious such as liver and muscle problems. are very effective in lowering LDL (bad) cholesterol levels are safe for most people have side effects that are infrequent, but potentially serious such as liver and muscle problems. Ezetimibe - lowers LDL (bad) cholesterol   - may be used with statins or alone  -  acts within the intestine to block absorption of cholesterol. lowers LDL (bad) cholesterol may be used with statins or alone acts within the intestine to block absorption of cholesterol. Bile acid sequestrants - lower LDL (bad) cholesterol levels  - are sometimes prescribed with statins  - are not usually prescribed alone to lower cholesterol. lower LDL (bad) cholesterol levels are sometimes prescribed with statins are not usually prescribed alone to lower cholesterol. Nicotinic acid - lowers LDL (bad) cholesterol and triglycerides, and raises HDL (good) cholesterol  - should be used only under a doctor's supervision. lowers LDL (bad) cholesterol and triglycerides, and raises HDL (good) cholesterol should be used only under a doctor's supervision. Fibrates - mainly lower triglycerides  - may increase HDL (good) cholesterol levels  - may increase the risk of muscle problems when used with a statin. mainly lower triglycerides may increase HDL (good) cholesterol levels may increase the risk of muscle problems when used with a statin. + NIHSeniorHealth + High Blood Cholesterol
What is (are) Peripheral Arterial Disease (P.A.D.) ?
Arteries Clogged With Plaque Peripheral arterial disease (P.A.D.) is a disease in which plaque (plak) builds up in the arteries that carry blood to your head, organs, and limbs. Plaque is made up of fat, cholesterol, calcium, fibrous tissue, and other substances in the blood. When plaque builds up in the body's arteries, the condition is called atherosclerosis (ATH-er-o-skler-O-sis). Over time, plaque can harden and narrow the arteries. This limits the flow of oxygen-rich blood to your organs and other parts of your body. P.A.D. usually affects the arteries in the legs, but it can also affect the arteries that carry blood from your heart to your head, arms, kidneys, and stomach. Blocked blood flow to your legs can cause pain and numbness. It also can raise your risk of getting an infection in the affected limbs. Your body may have a hard time fighting the infection. Why is P.A.D. Dangerous? Over time, the plaque may crack and cause blood clots to form. These blood clots can block arteries, causing pain, numbness, inflammation, and even permanent tissue damage in the affected part of the body. If severe enough, blocked blood flow can cause tissue death (also called gangrene.) In very serious cases, this can lead to leg amputation. P.A.D. currently affects 8 million to 12 million Americans. About 1 in every 20 Americans over the age of 50 has P.A.D. African Americans are more than twice as likely as Caucasians to have P.A.D. If you have P.A.D., your risk of coronary artery disease, heart attack, stroke, and transient ischemic attack ("mini-stroke") is much higher than in people without P.A.D. If you have coronary artery disease, you have a 1 in 3 chance of having blocked leg arteries. Although P.A.D. is serious, it is treatable. If you have the disease, it's important to see your doctor regularly and treat the underlying atherosclerosis. Other Names for Peripheral Arterial Disease -  Atherosclerotic peripheral arterial disease   -  Claudication (klaw-dih-KA-shen)   -  Hardening of the arteries   -  Leg cramps from poor circulation   -  Peripheral vascular disease   -  Poor circulation   -  Vascular disease  Atherosclerotic peripheral arterial disease Claudication (klaw-dih-KA-shen) Hardening of the arteries Leg cramps from poor circulation Peripheral vascular disease Poor circulation Vascular disease + NIHSeniorHealth + Peripheral Arterial Disease (P.A.D.)
What are the symptoms of Peripheral Arterial Disease (P.A.D.) ?
Common Symptoms Some people with P.A.D. do not have any symptoms. Others may have a number of signs and symptoms. People who have P.A.D. may notice symptoms when walking or climbing stairs. These symptoms may include pain, aching, or heaviness in the leg muscles. Symptoms may also include - pain  - aching, or heaviness in the leg muscles  - cramping in the affected leg(s) and in the buttocks, thighs, calves, and feet. pain aching, or heaviness in the leg muscles cramping in the affected leg(s) and in the buttocks, thighs, calves, and feet. They may go away after resting. These symptoms are called intermittent claudication (klaw-dih-KA-shen). If You Have Leg Pain If you have leg pain when you walk or climb stairs, talk to your doctor. Sometimes older people think that leg pain is part of aging when it could be P.A.D. Tell your doctor if you're feeling pain in your legs, and discuss whether you should be tested for P.A.D. Other Possible Signs Possible signs of P.A.D. include - weak or absent pulses in the legs or feet  - sores or wounds on the toes, feet, or legs that heal slowly, poorly, or not at all  - a pale or bluish color to the skin  - a lower temperature in one leg compared to the other leg  - poor toenail growth and decreased leg hair growth  - erectile dysfunction, especially in men who have diabetes. weak or absent pulses in the legs or feet sores or wounds on the toes, feet, or legs that heal slowly, poorly, or not at all a pale or bluish color to the skin a lower temperature in one leg compared to the other leg poor toenail growth and decreased leg hair growth erectile dysfunction, especially in men who have diabetes. Should I be Checked for P.A.D.? Even if you don't have symptoms or signs of P.A.D., you could still have the disease. Ask your doctor whether you should get checked for P.A.D. if you are - age 70 or older  - age 50 or older and have a history of smoking or diabetes   - younger than 50 years old and have diabetes and one or more risk factors for atherosclerosis. These risk factors include high cholesterol levels, high blood pressure, smoking, and being overweight. age 70 or older age 50 or older and have a history of smoking or diabetes younger than 50 years old and have diabetes and one or more risk factors for atherosclerosis. These risk factors include high cholesterol levels, high blood pressure, smoking, and being overweight. + NIHSeniorHealth + Peripheral Arterial Disease (P.A.D.)
What is (are) Peripheral Arterial Disease (P.A.D.) ?
Peripheral arterial disease (P.A.D.) is a disease in which plaque (plak) builds up in the arteries that carry blood to your head, organs, and limbs. Plaque is made up of fat, cholesterol, calcium, fibrous tissue, and other substances in the blood. P.A.D. currently affects millions of Americans, and about 1 in every 20 Americans over the age of 50 has P.A.D. + NIHSeniorHealth + Peripheral Arterial Disease (P.A.D.)
What causes Peripheral Arterial Disease (P.A.D.) ?
The most common cause of P.A.D. is atherosclerosis, a buildup of plaque in the arteries. Over time, plaque can harden and narrow the arteries. This limits the flow of oxygen-rich blood to your organs and other parts of your body. + NIHSeniorHealth + Peripheral Arterial Disease (P.A.D.)
Who is at risk for Peripheral Arterial Disease (P.A.D.)? ?
Smoking is the main risk factor for P.A.D. Your risk of P.A.D. increases four times if you smoke. Smoking also raises your risk for other diseases, such as coronary heart disease (CHD). On average, smokers who develop P.A.D. have symptoms 10 years earlier than nonsmokers who develop P.A.D. As you get older, your risk for P.A.D. increases, usually starting in your fifties. Older age combined with other risk factors, such as smoking or diabetes, also puts you at higher risk. African American men and women have a greater risk of developing P.A.D. than Caucasians. Your risk for P.A.D. is higher if you have diabetes, high cholesterol, high blood pressure, heart disease, or have had a stroke. A family history of these conditions also makes P.A.D. more likely. + NIHSeniorHealth + Peripheral Arterial Disease (P.A.D.)
What are the symptoms of Peripheral Arterial Disease (P.A.D.) ?
People who have P.A.D. may have symptoms when walking or climbing stairs. These may include pain, numbness, aching, or heaviness in the leg muscles. Symptoms may also include cramping in the affected leg(s) and in the buttocks, thighs, calves, and feet. Some possible signs of P.A.D. include - weak or absent pulses in the legs or feet  - sores or wounds on the toes, feet, or legs that heal slowly  - a pale or bluish color to the skin  - poor nail growth on the toes and decreased hair growth on the legs  - erectile dysfunction, especially among men who have diabetes. weak or absent pulses in the legs or feet sores or wounds on the toes, feet, or legs that heal slowly a pale or bluish color to the skin poor nail growth on the toes and decreased hair growth on the legs erectile dysfunction, especially among men who have diabetes. + NIHSeniorHealth + Peripheral Arterial Disease (P.A.D.)
How to diagnose Peripheral Arterial Disease (P.A.D.) ?
There are several tests used to diagnose P.A.D. These include - an ankle-brachial index (ABI). This test compares blood pressure in your ankle to blood pressure in your arm. It shows how well blood is flowing in your limbs.  - a Doppler ultrasound. This test uses sound waves to show whether a blood vessel is blocked. A blood pressure cuff and special device measure blood flow in the veins and arteries of the limbs. A Doppler ultrasound can help find out how where P.A.D. is.   - a treadmill test. This test shows if you have any problems during normal walking, how severe your symptoms are, and what level of exercise brings them on.  - a magnetic resonance angiogram (MRA). This test uses magnetic and radio waves to take pictures of your blood vessels. An MRA can find the location of a blocked blood vessel and show how severe the blockage is.   - an arteriogram. This test is used to find the exact location of a blocked artery. Dye is injected through a needle or catheter (thin tube) into an artery, then an X-ray is taken. The pictures from the X-ray can show the location, type, and extent of the blockage in the artery.   - blood tests. These tests check for P.A.D. risk factors such as diabetes and high blood cholesterol levels.  an ankle-brachial index (ABI). This test compares blood pressure in your ankle to blood pressure in your arm. It shows how well blood is flowing in your limbs. a Doppler ultrasound. This test uses sound waves to show whether a blood vessel is blocked. A blood pressure cuff and special device measure blood flow in the veins and arteries of the limbs. A Doppler ultrasound can help find out how where P.A.D. is. a treadmill test. This test shows if you have any problems during normal walking, how severe your symptoms are, and what level of exercise brings them on. a magnetic resonance angiogram (MRA). This test uses magnetic and radio waves to take pictures of your blood vessels. An MRA can find the location of a blocked blood vessel and show how severe the blockage is. an arteriogram. This test is used to find the exact location of a blocked artery. Dye is injected through a needle or catheter (thin tube) into an artery, then an X-ray is taken. The pictures from the X-ray can show the location, type, and extent of the blockage in the artery. blood tests. These tests check for P.A.D. risk factors such as diabetes and high blood cholesterol levels. + NIHSeniorHealth + Peripheral Arterial Disease (P.A.D.)
How to prevent Peripheral Arterial Disease (P.A.D.) ?
Treatment and prevention for P.A.D. often includes making long-lasting lifestyle changes, such as - quitting smoking  - lowering blood pressure  - lowering high blood cholesterol levels  - lowering high blood glucose levels if you have diabetes  - getting regular physical activity  - following a healthy eating plan that's low in total fat, saturated fat, trans fat, cholesterol, and sodium (salt). quitting smoking lowering blood pressure lowering high blood cholesterol levels lowering high blood glucose levels if you have diabetes getting regular physical activity following a healthy eating plan that's low in total fat, saturated fat, trans fat, cholesterol, and sodium (salt). Two examples of healthy eating plans are Therapeutic Lifestyle Changes (TLC) and  Dietary Approaches to Stop Hypertension (DASH). + NIHSeniorHealth + Peripheral Arterial Disease (P.A.D.)
what research (or clinical trials) is being done for Peripheral Arterial Disease (P.A.D.) ?
The National Heart, Lung, and Blood Institute (NHLBI) supports research aimed at learning more about peripheral arterial disease (P.A.D.). For example, NHLBI-supported research on P.A.D. includes studies that - explore whether group walking sessions increase physical activity in people who have P.A.D.  - compare how effective certain exercise programs are at reducing leg pain in people who have P.A.D.  - examine how inflammation and insulin resistance affect people who have P.A.D.  explore whether group walking sessions increase physical activity in people who have P.A.D. compare how effective certain exercise programs are at reducing leg pain in people who have P.A.D. examine how inflammation and insulin resistance affect people who have P.A.D. Much of this research depends on the willingness of volunteers to take part in clinical trials. Clinical trials test new ways to prevent, diagnose, or treat various diseases and conditions. Carefully conducted clinical trials are the fastest and safest way to find treatments that work in people and ways to improve health. For more information about clinical trials related to P.A.D., talk with your doctor. You also can visit the following Web sites to learn more about clinical research and to search for clinical trials. - http://www.nih.gov/health/clinicaltrials/  - http://www.clinicaltrials.gov/  - http://www.nhlbi.nih.gov/studies/index.htm  - https://www.researchmatch.org/  - http://www.cleverstudy.org/ http://www.nih.gov/health/clinicaltrials/ http://www.clinicaltrials.gov/ http://www.nhlbi.nih.gov/studies/index.htm https://www.researchmatch.org/ http://www.cleverstudy.org/ + NIHSeniorHealth + Peripheral Arterial Disease (P.A.D.)
What is (are) Peripheral Arterial Disease (P.A.D.) ?
Here are links to more information about P.A.D. from the National Heart, Lung, and Blood Institute. -  What Is Peripheral Arterial Disease?  -  Atherosclerosis  -  The DASH Eating Plan  - Facts about P.A.D.   - Facts about P.A.D. (Spanish)  - Facts About P.A.D. for African Americans  -  Keep the Beat: Heart Healthy Recipes  - Smoking and Your Heart  -   Your Guide to Physical Activity and Your Heart  -  Stay in Circulation: Take Steps to Learn about P.A.D. - Stay in Circulation: Take Steps to Learn about P.A.D. Wallet Card  - Your Guide to Lowering Your Blood Pressure with DASH  -  Your Guide to Lowering Your Cholesterol with TLC What Is Peripheral Arterial Disease? Atherosclerosis The DASH Eating Plan Facts about P.A.D.  Facts about P.A.D. (Spanish) Facts About P.A.D. for African Americans  Keep the Beat: Heart Healthy Recipes Smoking and Your Heart  Your Guide to Physical Activity and Your Heart Stay in Circulation: Take Steps to Learn about P.A.D. Stay in Circulation: Take Steps to Learn about P.A.D. Wallet Card Your Guide to Lowering Your Blood Pressure with DASH Your Guide to Lowering Your Cholesterol with TLC For print resources and materials on P.A.D. visit http://www.nhlbi.nih.gov/health/public/heart/pad/index.html + NIHSeniorHealth + Peripheral Arterial Disease (P.A.D.)
What is (are) Prescription and Illicit Drug Abuse ?
Addiction is a chronic disease in which a person craves, seeks, and continues to abuse a legal (medication, alcohol, tobacco) or an illicit (illegal) drug, despite harmful consequences. People who are addicted continue to abuse the substance even though it can harm their physical or mental health, lead to accidents, or put others in danger. For more on drugs and the brain, see  Drugs, Brains and Behavior: The Science of Addiction. + NIHSeniorHealth + Prescription and Illicit Drug Abuse
What is (are) Prescription and Illicit Drug Abuse ?
Physical dependence is a normal process that can happen to anyone taking a medication for a long time. It means that the body (including the brain) is adapting to the presence of the drug, and the person may require a higher dosage or a different medication to get relief; this condition is known as tolerance. They may also suffer from withdrawal or feel sick when they stop taking the medication abruptly. However, the symptoms of withdrawal can usually be prevented or managed by a physician, which is why it is so important to talk to a doctor before stopping a medication. Someone who is addicted to a drug may also be physically dependent on it, but rather than benefitting from the drugs effects, an addicted person will continue to get worse with continued or increasing drug abuse. An addicted person compulsively seeks and abuses drugs, despite their negative consequences. + NIHSeniorHealth + Prescription and Illicit Drug Abuse
What are the symptoms of Prescription and Illicit Drug Abuse ?
A persons behavior, especially changes in behavior, can signal a possible substance abuse problem. For example, you may notice that an older adult seems worried about whether a medicine is really working, or complains that a doctor refuses to write a prescription. He or she may have new problems doing everyday tasks or withdraw from family, friends, and normal activities. Other possible warning signs include - rapid increases in the amount of medication needed  - frequent requests for refills of certain medicines  - a person not seeming like themselves (showing a general lack of interest or being overly energetic)  - "doctor shopping" -- moving from provider to provider in an effort to get several prescriptions for the same medication  - use of more than one pharmacy  - false or forged prescriptions. rapid increases in the amount of medication needed frequent requests for refills of certain medicines a person not seeming like themselves (showing a general lack of interest or being overly energetic) "doctor shopping" -- moving from provider to provider in an effort to get several prescriptions for the same medication use of more than one pharmacy false or forged prescriptions. + NIHSeniorHealth + Prescription and Illicit Drug Abuse
What is (are) Prescription and Illicit Drug Abuse ?
The prescription medications most commonly abused by people of any age are opioids (painkillers), depressants, and stimulants. Doctors prescribe opioids to relieve pain and, sometimes, to treat severe coughs and diarrhea. Common opioid prescription medications include the following: - morphine (MS Contin, Kadian, Avinza), which is used before and after surgical procedures to treat severe pain  - codeine (Tylenol with Codeine, Robitussin AC), which is prescribed for mild pain  - hydrocodone (Vicodin, Lortab, Zydone), which is prescribed to relieve moderate to severe pain  - oxycodone (OxyContin, Percodan, Percocet, Tylox, Roxicet), which is used to relieve moderate to severe pain   - fentanyl (Duragesic), which is a strong pain medication typically delivered through a pain patch and prescribed for severe ongoing pain  morphine (MS Contin, Kadian, Avinza), which is used before and after surgical procedures to treat severe pain codeine (Tylenol with Codeine, Robitussin AC), which is prescribed for mild pain hydrocodone (Vicodin, Lortab, Zydone), which is prescribed to relieve moderate to severe pain oxycodone (OxyContin, Percodan, Percocet, Tylox, Roxicet), which is used to relieve moderate to severe pain fentanyl (Duragesic), which is a strong pain medication typically delivered through a pain patch and prescribed for severe ongoing pain For more on opioids, see  What Are the Possible Consequences of Opioid Use and Abuse?" Depressants are used to treat anxiety and sleep disorders. The types of depressants that are most commonly abused are barbiturates (Secobarbital ,Mebaral and Nembutal) and benzodiazepines (Valium, Librium, and Xanax). For more on depressants, see What Are the Possible Consequences of CNS Depressant Use and Abuse?"  Stimulants are used to treat narcolepsy (a sleep disorder), attention deficit hyperactivity disorder (ADHD), and depression that has not responded to other treatments. These medications increase alertness, attention, and energy. Stimulants include methylphenidate (Ritalin and Concerta), and amphetamines (Adderall). For more on stimulants, see  What Are the Possible Consequences of Stimulant Use and Abuse?" + NIHSeniorHealth + Prescription and Illicit Drug Abuse
What causes Prescription and Illicit Drug Abuse ?
Medications affect older people differently than younger people because aging changes how the body and brain handle these substances. As we age, our bodies change and cannot break down and get rid of substances as easily as before. This means that even a small amount of a medicine or a drug can have a strong effect. If you take medications the wrong way or abuse illicit drugs, this can have a serious effect on your health and make existing health problems worse. As people age, they may also become more sensitive to alcohols effects. For more information on the dangers of mixing alcohol and medicines, see Alcohol Use and Older Adults." + NIHSeniorHealth + Prescription and Illicit Drug Abuse
What is (are) Prescription and Illicit Drug Abuse ?
Marijuana is the most abused illicit drug among people 50 and older. + NIHSeniorHealth + Prescription and Illicit Drug Abuse
What are the treatments for Prescription and Illicit Drug Abuse ?
Although under federal law, marijuana is illegal to use under any circumstance, in some states doctors are allowed to prescribe it for medical use. However, solid data on marijuanas health benefits is lacking, and for smoked marijuana many health experts have concerns about the potential negative effects on the lungs and respiratory system. The U.S. Food and Drug Administration has not approved smoked marijuana to treat any disease. They have approved two medications that are chemically similar to marijuana to treat wasting disease (extreme weight loss) in people with AIDS and to treat nausea and vomiting associated with cancer treatment. + NIHSeniorHealth + Prescription and Illicit Drug Abuse
What are the symptoms of Prescription and Illicit Drug Abuse ?
Not always. Some warning signs, such as sleep problems, falls, mood swings, anxiety, depression, and memory problems -- can also be signs of other health conditions. As a result, doctors and family members often do not realize that an older person has a drug problem, and people may not get the help they need. + NIHSeniorHealth + Prescription and Illicit Drug Abuse
What are the treatments for Prescription and Illicit Drug Abuse ?
Depending on the substance(s) involved, treatment may include medications, behavioral treatments, or a combination. A doctor, substance abuse counselor, or other health professional can determine the right treatment for an individual. Treatment helps people reduce the powerful effects of drugs on the body and brain. In doing so, treatment helps people improve their physical health and everyday functioning and regain control of their lives. Once in treatment, older adults do just as well or better than younger adults. + NIHSeniorHealth + Prescription and Illicit Drug Abuse