fenil210/Med-Lamma huggingface dataset:
How to prevent Diabetic Heart Disease ?
Taking action to control risk factors can help prevent or delay heart disease in people who have diabetes and in those who don't. Your risk of heart disease increases with the number of risk factors you have.
                
One step you can take is to adopt a healthy lifestyle. A healthy lifestyle should be part of a lifelong approach to healthy living. A healthy lifestyle includes:
                
Following a healthy diet
                
Maintaining a healthy weight
                
Being physically active
                
Quitting smoking
                
Managing stress
                
You also should know your family history of diabetes and heart disease. If you or someone in your family has diabetes, heart disease, or both, let your doctor know.
                
Your doctor may prescribe medicines to control certain risk factors, such as high blood pressure and high blood cholesterol. Take all of your medicines exactly as your doctor advises.
                
People who have diabetes also need good blood sugar control. Controlling your blood sugar level is good for heart health. Ask your doctor about the best ways to control your blood sugar level.
                
For more information about lifestyle changes and medicines, go to "How Is Diabetic Heart Disease Treated?" + NHLBI + Diabetic Heart Disease
What is (are) Bronchopulmonary Dysplasia ?
Bronchopulmonary (BRONG-ko-PUL-mo-NAR-e) dysplasia (dis-PLA-ze-ah), or BPD, is a serious lung condition that affects infants. BPD mostly affects premature infants who need oxygen therapy (oxygen given through nasal prongs, a mask, or a breathing tube).
                
Most infants who develop BPD are born more than 10 weeks before their due dates, weigh less than 2 pounds (about 1,000 grams) at birth, and have breathing problems. Infections that occur before or shortly after birth also can contribute to BPD.
                
Some infants who have BPD may need long-term breathing support from nasal continuous positive airway pressure (NCPAP) machines or ventilators.
                
Overview
                
Many babies who develop BPD are born with serious respiratory distress syndrome (RDS). RDS is a breathing disorder that mostly affects premature newborns. These infants' lungs aren't fully formed or aren't able to make enough surfactant (sur-FAK-tant).
                
Surfactant is a liquid that coats the inside of the lungs. It helps keep them open so an infant can breathe in air once he or she is born.
                
Without surfactant, the lungs collapse, and the infant has to work hard to breathe. He or she might not be able to breathe in enough oxygen to support the body's organs. Without proper treatment, the lack of oxygen may damage the infant's brain and other organs.
                
Babies who have RDS are treated with surfactant replacement therapy. They also may need oxygen therapy. Shortly after birth, some babies who have RDS also are treated with NCPAP or ventilators (machines that support breathing).
                
Often, the symptoms of RDS start to improve slowly after about a week. However, some babies get worse and need more oxygen or breathing support from NCPAP or a ventilator.
                
If premature infants still require oxygen therapy by the time they reach their original due dates, they're diagnosed with BPD.
                
Outlook
                
Advances in care now make it possible for more premature infants to survive. However, these infants are at high risk for BPD.
                
Most babies who have BPD get better in time, but they may need treatment for months or even years. They may continue to have lung problems throughout childhood and even into adulthood. There's some concern about whether people who had BPD as babies can ever have normal lung function.
                
As children who have BPD grow, their parents can help reduce the risk of BPD complications. Parents can encourage healthy eating habits and good nutrition. They also can avoid cigarette smoke and other lung irritants. + NHLBI + Bronchopulmonary Dysplasia
What causes Bronchopulmonary Dysplasia ?
Bronchopulmonary dysplasia (BPD) develops as a result of an infant's lungs becoming irritated or inflamed.
                
The lungs of premature infants are fragile and often aren't fully developed. They can easily be irritated or injured within hours or days of birth. Many factors can damage premature infants' lungs.
                
Ventilation
                
Newborns who have breathing problems or can't breathe on their own may need ventilator support. Ventilators are machines that use pressure to blow air into the airways and lungs.
                
Although ventilator support can help premature infants survive, the machine's pressure might irritate and harm the babies' lungs. For this reason, doctors only recommend ventilator support when necessary.
                
High Levels of Oxygen
                
Newborns who have breathing problems might need oxygen therapy (oxygen given through nasal prongs, a mask, or a breathing tube). This treatment helps the infants' organs get enough oxygen to work well.
                
However, high levels of oxygen can inflame the lining of the lungs and injure the airways. Also, high levels of oxygen can slow lung development in premature infants.
                
Infections
                
Infections can inflame the lungs. As a result, the airways narrow, which makes it harder for premature infants to breathe. Lung infections also increase the babies' need for extra oxygen and breathing support.
                
Heredity
                
Studies show that heredity may play a role in causing BPD. More studies are needed to confirm this finding. + NHLBI + Bronchopulmonary Dysplasia
Who is at risk for Bronchopulmonary Dysplasia? ?
The more premature an infant is and the lower his or her birth weight, the greater the risk of bronchopulmonary dysplasia (BPD).
                
Most infants who develop BPD are born more than 10 weeks before their due dates, weigh less than 2 pounds (about 1,000 grams) at birth, and have breathing problems. Infections that occur before or shortly after birth also can contribute to BPD.
                
The number of babies who have BPD is higher now than in the past. This is because of advances in care that help more premature infants survive.
                
Many babies who develop BPD are born with serious respiratory distress syndrome (RDS). However, some babies who have mild RDS or don't have RDS also develop BPD. These babies often have very low birth weights and one or more other conditions, such as patent ductus arteriosus (PDA) and sepsis.
                
PDA is a heart problem that occurs soon after birth in some babies. Sepsis is a serious bacterial infection in the bloodstream. + NHLBI + Bronchopulmonary Dysplasia
What are the symptoms of Bronchopulmonary Dysplasia ?
Many babies who develop bronchopulmonary dysplasia (BPD) are born with serious respiratory distress syndrome (RDS). The signs and symptoms of RDS at birth are:
                
Rapid, shallow breathing
                
Sharp pulling in of the chest below and between the ribs with each breath
                
Grunting sounds
                
Flaring of the nostrils
                
Babies who have RDS are treated with surfactant replacement therapy. They also may need oxygen therapy (oxygen given through nasal prongs, a mask, or a breathing tube).
                
Shortly after birth, some babies who have RDS also are treated with nasal continuous positive airway pressure (NCPAP) or ventilators (machines that support breathing).
                
Often, the symptoms of RDS start to improve slowly after about a week. However, some babies get worse and need more oxygen or breathing support from NCPAP or a ventilator.
                
A first sign of BPD is when premature infantsusually those born more than 10 weeks earlystill need oxygen therapy by the time they reach their original due dates. These babies are diagnosed with BPD.
                
Infants who have severe BPD may have trouble feeding, which can lead to delayed growth. These babies also may develop:
                
Pulmonary hypertension (PH). PH is increased pressure in the pulmonary arteries. These arteries carry blood from the heart to the lungs to pick up oxygen.
                
Cor pulmonale. Cor pulmonale is failure of the right side of the heart. Ongoing high blood pressure in the pulmonary arteries and the lower right chamber of the heart causes this condition. + NHLBI + Bronchopulmonary Dysplasia
How to diagnose Bronchopulmonary Dysplasia ?
Infants who are born earlyusually more than 10 weeks before their due datesand still need oxygen therapy by the time they reach their original due dates are diagnosed with bronchopulmonary dysplasia (BPD).
                
BPD can be mild, moderate, or severe. The diagnosis depends on how much extra oxygen a baby needs at the time of his or her original due date. It also depends on how long the baby needs oxygen therapy.
                
To help confirm a diagnosis of BPD, doctors may recommend tests, such as:
                
Chest x ray. A chest x ray takes pictures of the structures inside the chest, such as the heart and lungs. In severe cases of BPD, this test may show large areas of air and signs of inflammation or infection in the lungs. A chest x ray also can detect problems (such as a collapsed lung) and show whether the lungs aren't developing normally.
                
Blood tests. Blood tests are used to see whether an infant has enough oxygen in his or her blood. Blood tests also can help determine whether an infection is causing an infant's breathing problems.
                
Echocardiography. This test uses sound waves to create a moving picture of the heart. Echocardiography is used to rule out heart defects or pulmonary hypertension as the cause of an infant's breathing problems + NHLBI + Bronchopulmonary Dysplasia
How to prevent Bronchopulmonary Dysplasia ?
Taking steps to ensure a healthy pregnancy might prevent your infant from being born before his or her lungs have fully developed. These steps include:
                
Seeing your doctor regularly during your pregnancy
                
Following a healthy diet
                
Not smoking and avoiding tobacco smoke, alcohol, and illegal drugs
                
Controlling any ongoing medical conditions you have
                
Preventing infection
                
If your doctor thinks that you're going to give birth too early, he or she may give you injections of a corticosteroid medicine.
                
The medicine can speed up surfactant production in your baby. Surfactant is a liquid that coats the inside of the lungs. It helps keep them open so your infant can breathe in air once he or she is born.
                
Usually, within about 24 hours of your taking this medicine, the baby's lungs start making enough surfactant. This will reduce the infant's risk of respiratory distress syndrome (RDS), which can lead to bronchopulmonary dysplasia (BPD).
                
Corticosteroids also can help your baby's lungs, brain, and kidneys develop more quickly while he or she is in the womb.
                
If your baby does develop RDS, it will probably be fairly mild. If the RDS isn't mild, BPD will likely develop. + NHLBI + Bronchopulmonary Dysplasia
What is (are) Hemophilia ?
Espaol
                
Hemophilia (heem-o-FILL-ee-ah) is a rare bleeding disorder in which the blood doesn't clot normally.
                
If you have hemophilia, you may bleed for a longer time than others after an injury. You also may bleed inside your body (internally), especially in your knees, ankles, and elbows. This bleeding can damage your organs and tissues and may be life threatening.
                
Overview
                
Hemophilia usually is inherited. "Inherited means that the disorder is passed from parents to children through genes.
                
People born with hemophilia have little or no clotting factor. Clotting factor is a protein needed for normal blood clotting. There are several types of clotting factors. These proteins work with platelets (PLATE-lets) to help the blood clot.
                
Platelets are small blood cell fragments that form in the bone marrowa sponge-like tissue in the bones. Platelets play a major role in blood clotting. When blood vessels are injured, clotting factors help platelets stick together to plug cuts and breaks on the vessels and stop bleeding.
                
The two main types of hemophilia are A and B. If you have hemophilia A, you're missing or have low levels of clotting factor VIII (8). About 8 out of 10 people who have hemophilia have type A. If you have hemophilia B, you're missing or have low levels of clotting factor IX (9).
                
Rarely, hemophilia can be acquired. "Acquired means you aren't born with the disorder, but you develop it during your lifetime. This can happen if your body forms antibodies (proteins) that attack the clotting factors in your bloodstream. The antibodies can prevent the clotting factors from working.
                
This article focuses on inherited hemophilia.
                
Outlook
                
Hemophilia can be mild, moderate, or severe, depending on how much clotting factor is in your blood. About 7 out of 10 people who have hemophilia A have the severe form of the disorder.
                
People who don't have hemophilia have a factor VIII activity of 100 percent. People who have severe hemophilia A have a factor VIII activity of less than 1 percent.
                
Hemophilia usually occurs in males (with rare exceptions). About 1 in 5,000 males are born with hemophilia each year. + NHLBI + Hemophilia
What causes Hemophilia ?
A defect in one of the genes that determines how the body makes blood clotting factor VIII or IX causes hemophilia. These genes are located on the X chromosomes (KRO-muh-somz).
                
Chromosomes come in pairs. Females have two X chromosomes, while males have one X and one Y chromosome. Only the X chromosome carries the genes related to clotting factors.
                
A male who has a hemophilia gene on his X chromosome will have hemophilia. When a female has a hemophilia gene on only one of her X chromosomes, she is a "hemophilia carrier and can pass the gene to her children. Sometimes carriers have low levels of clotting factor and have symptoms of hemophilia, including bleeding. Clotting factors are proteins in the blood that work together with platelets to stop or control bleeding.
                
Very rarely, a girl may be born with a very low clotting factor level and have a greater risk for bleeding, similar to boys who have hemophilia and very low levels of clotting factor. There are several hereditary and genetic causes of this much rarer form of hemophilia in females.
                
Some males who have the disorder are born to mothers who aren't carriers. In these cases, a mutation (random change) occurs in the gene as it is passed to the child.
                
Below are two examples of how the hemophilia gene is inherited.
                
Inheritance Pattern for HemophiliaExample 1
                

                
Each daughter has a 50 percent chance of inheriting the hemophilia gene from her mother and being a carrier. Each son has a 50 percent chance of inheriting the hemophilia gene from his mother and having hemophilia.
                
Inheritance Pattern for HemophiliaExample 2
                

                
Each daughter will inherit the hemophilia gene from her father and be a carrier. None of the sons will inherit the hemophilia gene from their father; thus, none will have hemophilia. + NHLBI + Hemophilia
What are the symptoms of Hemophilia ?
The major signs and symptoms of hemophilia are excessive bleeding and easy bruising.
                
Excessive Bleeding
                
The extent of bleeding depends on how severe the hemophilia is.
                
Children who have mild hemophilia may not have signs unless they have excessive bleeding from a dental procedure, an accident, or surgery. Males who have severe hemophilia may bleed heavily after circumcision.
                
Bleeding can occur on the body's surface (external bleeding) or inside the body (internal bleeding).
                
Signs of external bleeding may include:
                
Bleeding in the mouth from a cut or bite or from cutting or losing a tooth
                
Nosebleeds for no obvious reason
                
Heavy bleeding from a minor cut
                
Bleeding from a cut that resumes after stopping for a short time
                
Signs of internal bleeding may include:
                
Blood in the urine (from bleeding in the kidneys or bladder)
                
Blood in the stool (from bleeding in the intestines or stomach)
                
Large bruises (from bleeding into the large muscles of the body)
                
Bleeding in the Joints
                
Bleeding in the knees, elbows, or other joints is another common form of internal bleeding in people who have hemophilia. This bleeding can occur without obvious injury.
                
At first, the bleeding causes tightness in the joint with no real pain or any visible signs of bleeding. The joint then becomes swollen, hot to touch, and painful to bend.
                
Swelling continues as bleeding continues. Eventually, movement in the joint is temporarily lost. Pain can be severe. Joint bleeding that isn't treated quickly can damage the joint.
                
Bleeding in the Brain
                
Internal bleeding in the brain is a very serious complication of hemophilia. It can happen after a simple bump on the head or a more serious injury. The signs and symptoms of bleeding in the brain include:
                
Long-lasting, painful headaches or neck pain or stiffness
                
Repeated vomiting
                
Sleepiness or changes in behavior
                
Sudden weakness or clumsiness of the arms or legs or problems walking
                
Double vision
                
Convulsions or seizures + NHLBI + Hemophilia
How to diagnose Hemophilia ?
If you or your child appears to have a bleeding problem, your doctor will ask about your personal and family medical histories. This will reveal whether you or your family members, including women and girls, have bleeding problems. However, some people who have hemophilia have no recent family history of the disease.
                
You or your child also will likely have a physical exam and blood tests to diagnose hemophilia. Blood tests are used to find out:
                
How long it takes for your blood to clot
                
Whether your blood has low levels of any clotting factors
                
Whether any clotting factors are completely missing from your blood
                
The test results will show whether you have hemophilia, what type of hemophilia you have, and how severe it is.
                
Hemophilia A and B are classified as mild, moderate, or severe, depending on the amount of clotting factor VIII or IX in the blood.
                
The severity of symptoms can overlap between the categories. For example, some people who have mild hemophilia may have bleeding problems almost as often or as severe as some people who have moderate hemophilia.
                
Severe hemophilia can cause serious bleeding problems in babies. Thus, children who have severe hemophilia usually are diagnosed during the first year of life. People who have milder forms of hemophilia may not be diagnosed until they're adults.
                
The bleeding problems of hemophilia A and hemophilia B are the same. Only special blood tests can tell which type of the disorder you or your child has. Knowing which type is important because the treatments are different.
                
Pregnant women who are known hemophilia carriers can have the disorder diagnosed in their unborn babies as early as 12 weeks into their pregnancies.
                
Women who are hemophilia carriers also can have "preimplantation diagnosis" to have children who don't have hemophilia.
                
For this process, women have their eggs removed and fertilized by sperm in a laboratory. The embryos are then tested for hemophilia. Only embryos without the disorder are implanted in the womb. + NHLBI + Hemophilia
What is (are) Coronary Heart Disease ?
Espaol
                
Coronary heart disease (CHD) is a disease in which a waxy substance called plaque builds up inside the coronary arteries. These arteries supply oxygen-rich blood to your heart muscle.
                
When plaque builds up in the arteries, the condition is called atherosclerosis. The buildup of plaque occurs over many years.
                
Atherosclerosis
                

                
Over time, plaque can harden or rupture (break open). Hardened plaque narrows the coronary arteries and reduces the flow of oxygen-rich blood to the heart.
                
If the plaque ruptures, a blood clot can form on its surface. A large blood clot can mostly or completely block blood flow through a coronary artery. Over time, ruptured plaque also hardens and narrows the coronary arteries.
                
Overview
                
If the flow of oxygen-rich blood to your heart muscle is reduced or blocked, angina or a heart attack can occur.
                
Angina is chest pain or discomfort. It may feel like pressure or squeezing in your chest. The pain also can occur in your shoulders, arms, neck, jaw, or back. Angina pain may even feel like indigestion.
                
A heart attack occurs if the flow of oxygen-rich blood to a section of heart muscle is cut off. If blood flow isnt restored quickly, the section of heart muscle begins to die. Without quick treatment, a heart attack can lead to serious health problems or death.
                
Over time, CHD can weaken the heart muscle and lead to heart failure and arrhythmias. Heart failure is a condition in which your heart can't pump enough blood to meet your bodys needs. Arrhythmias are problems with the rate or rhythm of the heartbeat.
                
Outlook
                
Lifestyle changes, medicines, and medical procedures can help prevent or treat coronary heart disease. These treatments may reduce the risk of related health problems. + NHLBI + Coronary Heart Disease
What causes Coronary Heart Disease ?
Research suggests that coronary heart disease (CHD) starts when certain factors damage the inner layers of the coronary arteries. These factors include:
                
Smoking
                
High levels of certain fats and cholesterol in the blood
                
High blood pressure
                
High levels of sugar in the blood due to insulin resistance or diabetes
                
Blood vessel inflammation
                
Plaque might begin to build up where the arteries are damaged. The buildup of plaque in the coronary arteries may start in childhood.
                
Over time, plaque can harden or rupture (break open). Hardened plaque narrows the coronary arteries and reduces the flow of oxygen-rich blood to the heart. This can cause angina (chest pain or discomfort).
                
If the plaque ruptures, blood cell fragments called platelets (PLATE-lets) stick to the site of the injury. They may clump together to form blood clots.
                
Blood clots can further narrow the coronary arteries and worsen angina. If a clot becomes large enough, it can mostly or completely block a coronary artery and cause a heart attack. + NHLBI + Coronary Heart Disease