fenil210/Med-Lamma huggingface dataset:
What is (are) Rectal Cancer ?
Key Points
                    - Rectal cancer is a disease in which malignant (cancer) cells form in the tissues of the rectum.     - Health history affects the risk of developing rectal cancer.    - Signs of rectal cancer include a change in bowel habits or blood in the stool.    - Tests that examine the rectum and colon are used to detect (find) and diagnose rectal cancer.    - Certain factors affect prognosis (chance of recovery) and treatment options.
                
                
                    Rectal cancer is a disease in which malignant (cancer) cells form in the tissues of the rectum.
                    The rectum is part of the bodys digestive system. The digestive system takes in nutrients (vitamins, minerals, carbohydrates, fats, proteins, and water) from foods and helps pass waste material out of the body. The digestive system is made up of the esophagus, stomach, and the small and large intestines. The colon (large bowel) is the first part of the large intestine and is about 5 feet long. Together, the rectum and anal canal make up the last part of the large intestine and are 6-8 inches long. The anal canal ends at the anus (the opening of the large intestine to the outside of the body).     See the following PDQ summaries for more information about rectal cancer:         -  Unusual Cancers of Childhood Treatment (see Colorectal Cancer section)    -  Colorectal Cancer Prevention     -   Colorectal Cancer Screening    -  Gastrointestinal Stromal Tumors Treatment     -  Genetics of Colorectal Cancer + CancerGov + Rectal Cancer
Who is at risk for Rectal Cancer? ?
Health history affects the risk of developing rectal cancer. Anything that increases your chance of getting a disease is called a risk factor. Having a risk factor does not mean that you will get cancer; not having risk factors doesnt mean that you will not get cancer. Talk to your doctor if you think you may be at risk for colorectal cancer.    Risk factors for colorectal cancer include the following:            - Having a family history of colon or rectal cancer in a first-degree relative (parent, sibling, or child).     - Having a personal history of cancer of the colon, rectum, or ovary.     - Having a personal history of high-risk adenomas (colorectal polyps that are 1 centimeter or larger in size or that have cells that look abnormal under a microscope).     - Having inherited changes in certain genes that increase the risk of familial adenomatous polyposis (FAP) or Lynch syndrome (hereditary nonpolyposis colorectal cancer).     - Having a personal history of chronic ulcerative colitis or Crohn disease for 8 years or more.     - Having three or more alcoholic drinks per day.     - Smoking cigarettes.     - Being black.     - Being obese.           Older age is a main risk factor for most cancers. The chance of getting cancer increases as you get older. + CancerGov + Rectal Cancer
What are the symptoms of Rectal Cancer ?
Signs of rectal cancer include a change in bowel habits or blood in the stool. These and other signs and symptoms may be caused by rectal cancer or by other conditions. Check with your doctor if you have any of the following:         -  Blood (either bright red or very dark) in the stool.    - A change in bowel habits.               -  Diarrhea.       -  Constipation.      - Feeling that the bowel does not empty completely.      - Stools that are narrower or have a different shape than usual.             - General abdominal discomfort (frequent gas pains, bloating, fullness, or cramps).    - Change in appetite.    - Weight loss for no known reason.    - Feeling very tired. + CancerGov + Rectal Cancer
How to diagnose Rectal Cancer ?
Tests that examine the rectum and colon are used to detect (find) and diagnose rectal cancer. Tests used to diagnose rectal cancer include the following:         -   Physical exam and history : An exam of the body to check general signs of health, including checking for signs of disease, such as lumps or anything else that seems unusual. A history of the patients health habits and past illnesses and treatments will also be taken.    -   Digital rectal exam (DRE): An exam of the rectum. The doctor or nurse inserts a lubricated, gloved finger into the lower part of the rectum to feel for lumps or anything else that seems unusual. In women, the vagina may also be examined.    -   Colonoscopy : A procedure to look inside the rectum and colon for polyps (small pieces of bulging tissue), abnormal areas, or cancer. A colonoscope is a thin, tube-like instrument with a light and a lens for viewing. It may also have a tool to remove polyps or tissue samples, which are checked under a microscope for signs of cancer.    -   Biopsy : The removal of cells or tissues so they can be viewed under a microscope to check for signs of cancer. Tumor tissue that is removed during the biopsy may be checked to see if the patient is likely to have the gene mutation that causes HNPCC. This may help to plan treatment. The following tests may be used:               -  Reverse transcriptionpolymerase chain reaction (RTPCR) test: A laboratory test in which cells in a sample of tissue are studied using chemicals to look for certain changes in the structure or function of genes.      -  Immunohistochemistry : A test that uses antibodies to check for certain antigens in a sample of tissue. The antibody is usually linked to a radioactive substance or a dye that causes the tissue to light up under a microscope. This type of test may be used to tell the difference between different types of cancer.             -   Carcinoembryonic antigen (CEA) assay : A test that measures the level of CEA in the blood. CEA is released into the bloodstream from both cancer cells and normal cells. When found in higher than normal amounts, it can be a sign of rectal cancer or other conditions. + CancerGov + Rectal Cancer
What is the outlook for Rectal Cancer ?
Certain factors affect prognosis (chance of recovery) and treatment options. The prognosis (chance of recovery) and treatment options depend on the following:         - The stage of the cancer (whether it affects the inner lining of the rectum only, involves the whole rectum, or has spread to lymph nodes, nearby organs, or other places in the body).    - Whether the tumor has spread into or through the bowel wall.    - Where the cancer is found in the rectum.    - Whether the bowel is blocked or has a hole in it.    - Whether all of the tumor can be removed by surgery.    -  The patients general health.     - Whether the cancer has just been diagnosed or has recurred (come back). + CancerGov + Rectal Cancer
what research (or clinical trials) is being done for Rectal Cancer ?
Other types of treatment are being tested in clinical trials.
                    Information about clinical trials is available from the NCI website.
                
                
                    Patients may want to think about taking part in a clinical trial.
                    For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the cancer research process. Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment.   Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.   Patients who take part in clinical trials also help improve the way cancer will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
                
                
                    Patients can enter clinical trials before, during, or after starting their cancer treatment.
                    Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or reduce the side effects of cancer treatment.   Clinical trials are taking place in many parts of the country. See the Treatment Options section that follows for links to current treatment clinical trials. These have been retrieved from NCI's listing of clinical trials. + CancerGov + Rectal Cancer
What causes Childhood Astrocytomas ?
The cause of most childhood brain tumors is not known. + CancerGov + Childhood Astrocytomas
Who is at risk for Childhood Astrocytomas? ?
Anything that increases your risk of getting a disease is called a risk factor. Having a risk factor does not mean that you will get cancer; not having risk factors doesnt mean that you will not get cancer. Talk with your child's doctor if you think your child may be at risk. Possible risk factors for astrocytoma include:          - Past radiation therapy to the brain.    - Having certain genetic disorders, such as neurofibromatosis type 1 (NF1) or tuberous sclerosis. + CancerGov + Childhood Astrocytomas
What are the symptoms of Childhood Astrocytomas ?
The signs and symptoms of astrocytomas are not the same in every child. Signs and symptoms depend on the following:          - Where the tumor forms in the brain or spinal cord.    - The size of the tumor.    - How fast the tumor grows.    - The child's age and development.        Some tumors do not cause signs or symptoms. Signs and symptoms may be caused by childhood astrocytomas or by other conditions. Check with your child's doctor if your child has any of the following:         - Morning headache or headache that goes away after vomiting.    -  Nausea and vomiting.    - Vision, hearing, and speech problems.     - Loss of balance and trouble walking.     - Worsening handwriting or slow speech.    - Weakness or change in feeling on one side of the body.    - Unusual sleepiness.    - More or less energy than usual.    - Change in personality or behavior.    -  Seizures.    - Weight loss or weight gain for no known reason.     - Increase in the size of the head (in infants). + CancerGov + Childhood Astrocytomas
What is the outlook for Childhood Astrocytomas ?
Certain factors affect prognosis (chance of recovery) and treatment options. The prognosis (chance of recovery) and treatment options depend on the following:         - Whether the tumor is a low-grade or high-grade astrocytoma.    - Where the tumor has formed in the CNS and if it has spread to nearby tissue or to other parts of the body.    - How fast the tumor is growing.    - The child's age.    - Whether cancer cells remain after surgery.    - Whether there are changes in certain genes.    - Whether the child has NF1 or tuberous sclerosis.    - Whether the child has diencephalic syndrome (a condition which slows physical growth).    - Whether the child has intracranial hypertension (cerebrospinal fluid pressure within the skull is high) at the time of diagnosis.    - Whether the astrocytoma has just been diagnosed or has recurred (come back).        For recurrent astrocytoma, prognosis and treatment depend on how much time passed between the time treatment ended and the time the astrocytoma recurred. + CancerGov + Childhood Astrocytomas
What are the stages of Childhood Astrocytomas ?
Key Points
                    - The grade of the tumor is used to plan cancer treatment.          - Low-grade astrocytomas     - High-grade astrocytomas        - An MRI is done after surgery.
                
                
                    The grade of the tumor is used to plan cancer treatment.
                    Staging is the process used to find out how much cancer there is and if cancer has spread. It is important to know the stage in order to plan treatment.    There is no standard staging system for childhood astrocytoma. Treatment is based on the following:          - Whether the tumor is low grade or high grade.    - Whether the tumor is newly diagnosed or recurrent (has come back after treatment).        The grade of the tumor describes how abnormal the cancer cells look under a microscope and how quickly the tumor is likely to grow and spread.   The following grades are used:     Low-grade astrocytomas    Low-grade astrocytomas are slow-growing and rarely spread to other parts of the brain and spinal cord or other parts of the body. There are many types of low-grade astrocytomas. Low-grade astrocytomas can be either:            - Grade I tumors pilocytic astrocytoma, subependymal giant cell tumor, or angiocentric glioma.     - Grade II tumors diffuse astrocytoma, pleomorphic xanthoastrocytoma, or choroid glioma of the third ventricle.            Children who have neurofibromatosis type 1 may have more than one low-grade tumor in the brain. Children who have tuberous sclerosis have an increased risk of subependymal giant cell astrocytoma.       High-grade astrocytomas     High-grade astrocytomas are fast-growing and often spread within the brain and spinal cord. There are several types of high-grade astrocytomas. High grade astrocytomas can be either:            - Grade III tumors anaplastic astrocytoma or anaplastic pleomorphic xanthoastrocytoma.      - Grade IV tumors glioblastoma or diffuse midline glioma.             Childhood astrocytomas usually do not spread to other parts of the body.
                
                
                    An MRI is done after surgery.
                    An MRI (magnetic resonance imaging) is done in the first few days after surgery. This is to find out how much tumor, if any, remains after surgery and to plan further treatment. + CancerGov + Childhood Astrocytomas
what research (or clinical trials) is being done for Childhood Astrocytomas ?
New types of treatment are being tested in clinical trials.
                    This summary section describes treatments that are being studied in clinical trials. It may not mention every new treatment being studied. Information about clinical trials is available from the NCI website.     Other drug therapy     Lenalidomide is a type of angiogenesis inhibitor. It prevents the growth of new blood vessels that are needed by a tumor to grow.
                
                
                    Patients may want to think about taking part in a clinical trial.
                    For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the cancer research process. Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment.   Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.   Patients who take part in clinical trials also help improve the way cancer will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
                
                
                    Patients can enter clinical trials before, during, or after starting their cancer treatment.
                    Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or reduce the side effects of cancer treatment.   Clinical trials are taking place in many parts of the country. See the Treatment Options section that follows for links to current treatment clinical trials. These have been retrieved from NCI's listing of clinical trials. + CancerGov + Childhood Astrocytomas
What is (are) Metastatic Squamous Neck Cancer with Occult Primary ?
Key Points
                    - Metastatic squamous neck cancer with occult primary is a disease in which squamous cell cancer spreads to lymph nodes in the neck and it is not known where the cancer first formed in the body.    - Signs and symptoms of metastatic squamous neck cancer with occult primary include a lump or pain in the neck or throat.     - Tests that examine the tissues of the neck, respiratory tract, and upper part of the digestive tract are used to detect (find) and diagnose metastatic squamous neck cancer and the primary tumor.    - Certain factors affect prognosis (chance of recovery) and treatment options.
                
                
                    Metastatic squamous neck cancer with occult primary is a disease in which squamous cell cancer spreads to lymph nodes in the neck and it is not known where the cancer first formed in the body.
                    Squamous cells are thin, flat cells found in tissues that form the surface of the skin and the lining of body cavities such as the mouth, hollow organs such as the uterus and blood vessels, and the lining of the respiratory (breathing) and digestive tracts. Some organs with squamous cells are the esophagus, lungs, kidneys, and uterus. Cancer can begin in squamous cells anywhere in the body and metastasize (spread) through the blood or lymph system to other parts of the body.    When squamous cell cancer spreads to lymph nodes in the neck or around the collarbone, it is called metastatic squamous neck cancer. The doctor will try to find the primary tumor (the cancer that first formed in the body), because treatment for metastatic cancer is the same as treatment for the primary tumor. For example, when lung cancer spreads to the neck, the cancer cells in the neck are lung cancer cells and they are treated the same as the cancer in the lung. Sometimes doctors cannot find where in the body the cancer first began to grow. When tests cannot find a primary tumor, it is called an occult (hidden) primary tumor. In many cases, the primary tumor is never found. + CancerGov + Metastatic Squamous Neck Cancer with Occult Primary
What are the symptoms of Metastatic Squamous Neck Cancer with Occult Primary ?
Signs and symptoms of metastatic squamous neck cancer with occult primary include a lump or pain in the neck or throat. Check with your doctor if you have a lump or pain in your neck or throat that doesn't go away. These and other signs and symptoms may be caused by metastatic squamous neck cancer with occult primary. Other conditions may cause the same signs and symptoms. + CancerGov + Metastatic Squamous Neck Cancer with Occult Primary
What is the outlook for Metastatic Squamous Neck Cancer with Occult Primary ?
Certain factors affect prognosis (chance of recovery) and treatment options. The prognosis (chance of recovery) and treatment options depend on the following:         - The number and size of lymph nodes that have cancer in them.    - Whether the cancer has responded to treatment or has recurred (come back).    - How different from normal the cancer cells look under a microscope.    - The patient's age and general health.        Treatment options also depend on the following:         - Which part of the neck the cancer is in.    - Whether certain tumor markers are found. + CancerGov + Metastatic Squamous Neck Cancer with Occult Primary
What are the stages of Metastatic Squamous Neck Cancer with Occult Primary ?
Key Points
                    - After metastatic squamous neck cancer with occult primary has been diagnosed, tests are done to find out if cancer cells have spread to other parts of the body.    - There are three ways that cancer spreads in the body.
                
                
                    After metastatic squamous neck cancer with occult primary has been diagnosed, tests are done to find out if cancer cells have spread to other parts of the body.
                    The process used to find out if cancer has spread to other parts of the body is called staging. The results from tests and procedures used to detect and diagnose the primary tumor are also used to find out if cancer has spread to other parts of the body.    There is no standard staging system for metastatic squamous neck cancer with occult primary. The tumors are described as untreated or recurrent. Untreated metastatic squamous neck cancer with occult primary is cancer that is newly diagnosed and has not been treated, except to relieve signs and symptoms caused by the cancer.
                
                
                    There are three ways that cancer spreads in the body.
                    Cancer can spread through tissue, the lymph system, and the blood:         - Tissue. The cancer spreads from where it began by growing into nearby areas.     - Lymph system. The cancer spreads from where it began by getting into the lymph system. The cancer travels through the lymph vessels to other parts of the body.     - Blood. The cancer spreads from where it began by getting into the blood. The cancer travels through the blood vessels to other parts of the body. + CancerGov + Metastatic Squamous Neck Cancer with Occult Primary
what research (or clinical trials) is being done for Metastatic Squamous Neck Cancer with Occult Primary ?
New types of treatment are being tested in clinical trials.
                    This summary section describes treatments that are being studied in clinical trials. It may not mention every new treatment being studied. Information about clinical trials is available from the NCI website.     Chemotherapy     Chemotherapy is a cancer treatment that uses drugs to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. When chemotherapy is taken by mouth or injected into a vein or muscle, the drugs enter the bloodstream and can reach cancer cells throughout the body (systemic chemotherapy). When chemotherapy is placed directly into the cerebrospinal fluid, an organ, or a body cavity such as the abdomen, the drugs mainly affect cancer cells in those areas (regional chemotherapy).        Hyperfractionated radiation therapy     Hyperfractionated radiation therapy is a type of external radiation treatment in which a smaller than usual total daily dose of radiation is divided into two doses and the treatments are given twice a day. Hyperfractionated radiation therapy is given over the same period of time (days or weeks) as standard radiation therapy.
                
                
                    Patients may want to think about taking part in a clinical trial.
                    For some patients, taking part in a clinical trial may be the best treatment choice. Clinical trials are part of the cancer research process. Clinical trials are done to find out if new cancer treatments are safe and effective or better than the standard treatment.   Many of today's standard treatments for cancer are based on earlier clinical trials. Patients who take part in a clinical trial may receive the standard treatment or be among the first to receive a new treatment.   Patients who take part in clinical trials also help improve the way cancer will be treated in the future. Even when clinical trials do not lead to effective new treatments, they often answer important questions and help move research forward.
                
                
                    Patients can enter clinical trials before, during, or after starting their cancer treatment.
                    Some clinical trials only include patients who have not yet received treatment. Other trials test treatments for patients whose cancer has not gotten better. There are also clinical trials that test new ways to stop cancer from recurring (coming back) or reduce the side effects of cancer treatment.   Clinical trials are taking place in many parts of the country. See the Treatment Options section that follows for links to current treatment clinical trials. These have been retrieved from NCI's listing of clinical trials. + CancerGov + Metastatic Squamous Neck Cancer with Occult Primary