fenil210/Med-Lamma huggingface dataset:
What is the outlook for Oxygen Therapy ?
During an emergencysuch as a serious accident, possible heart attack, or other life-threatening eventyou might be started on oxygen therapy right away.
                
Otherwise, your doctor will decide whether you need oxygen therapy based on test results. An arterial blood gas test and a pulse oximetry test can measure the amount of oxygen in your blood.
                
For an arterial blood gas test, a small needle is inserted into an artery, usually in your wrist. A sample of blood is taken from the artery. The sample is then sent to a laboratory, where its oxygen level is measured.
                
For a pulse oximetry test, a small sensor is attached to your fingertip or toe. The sensor uses light to estimate how much oxygen is in your blood.
                
If the tests show that your blood oxygen level is low, your doctor may prescribe oxygen therapy. In the prescription, your doctor will include the number of liters of oxygen per minute that you need (oxygen flow rate). He or she also will include how often you need to use the oxygen (frequency of use).
                
Frequency of use includes when and for how long you should use the oxygen. Depending on your condition and blood oxygen level, you may need oxygen only at certain times, such as during sleep or while exercising.
                
If your doctor prescribes home oxygen therapy, he or she can help you find a home equipment provider. The provider will give you the equipment and other supplies you need. + NHLBI + Oxygen Therapy
What is the outlook for Oxygen Therapy ?
During an emergencysuch as a serious accident, possible heart attack, or other life-threatening eventyou might be started on oxygen therapy right away.
                
While you're in the hospital, your doctor will check on you to make sure you're getting the right amount of oxygen. Nurses or respiratory therapists also may assist with the oxygen therapy.
                
If you're having oxygen therapy at home, a home equipment provider will help you set up the oxygen therapy equipment at your house.
                
Trained staff will show you how to use and take care of the equipment. They'll supply the oxygen and teach you how to safely handle it.
                
Because oxygen poses a fire risk, you'll need to take certain safety steps. Oxygen isn't explosive, but it can worsen a fire. In the presence of oxygen, a small fire can quickly get out of control. Also, the cylinder that compressed oxygen gas comes in can explode if it's exposed to heat.
                
Your home equipment provider will give you a complete list of safety steps that you'll need to follow at home and in public. For example, while on oxygen, you should:
                
Never smoke or be around people who are smoking
                
Never use paint thinners, cleaning fluids, gasoline, aerosol sprays, and other flammable materials
                
Stay at least 5 feet away from gas stoves, candles, and other heat sources
                
When you're not using the oxygen, keep it in a large, airy room. Never store compressed oxygen gas cylinders and liquid oxygen containers in small, enclosed places, such as in closets, behind curtains, or under clothes.
                
Oxygen containers let off small amounts of oxygen. These small amounts can build up to harmful levels if they're allowed to escape into small spaces. + NHLBI + Oxygen Therapy
Who is at risk for Oxygen Therapy? ?
Oxygen therapy can cause complications and side effects. These problems might include a dry or bloody nose, skin irritation from the nasal cannula or face mask, fatigue (tiredness), and morning headaches.
                
If these problems persist, tell your doctor and home equipment provider. Depending on the problem, your doctor may need to change your oxygen flow rate or the length of time you're using the oxygen.
                
If nose dryness is a problem, your doctor may recommend a nasal spray or have a humidifier added to your oxygen equipment.
                
If you have an uncomfortable nasal cannula or face mask, your home equipment provider can help you find a device that fits better. Your provider also can recommend over-the-counter gels and devices that are designed to lessen skin irritation.
                
Complications from transtracheal oxygen therapy can be more serious. With this type of oxygen therapy, oxygen is delivered through a tube inserted into your windpipe through the front of your neck.
                
With transtracheal oxygen therapy:
                
Mucus balls might develop on the tube inside the windpipe. Mucus balls tend to form as a result of the oxygen drying out the airways. Mucus balls can cause coughing and clog the windpipe or tube.
                
Problems with the tube slipping or breaking.
                
Infection.
                
Injury to the lining of the windpipe.
                
Proper medical care and correct handling of the tube and other supplies may reduce the risk of complications.
                
Other Risks
                
In certain people, oxygen therapy may suppress the drive to breathe, affecting how well the respiratory system works. This is managed by adjusting the oxygen flow rate.
                
Oxygen poses a fire risk, so you'll need to take certain safety steps. Oxygen itself isn't explosive, but it can worsen a fire. In the presence of oxygen, a small fire can quickly get out of control. Also, the cylinder that compressed oxygen gas comes in might explode if exposed to heat.
                
Your home equipment provider will give you a complete list of safety steps you'll need to take at home and when out in public.
                
For example, when you're not using the oxygen, keep it in an airy room. Never store compressed oxygen gas cylinders and liquid oxygen containers in small, enclosed places, such as in closets, behind curtains, or under clothes.
                
Oxygen containers let off small amounts of oxygen. These small amounts can build up to harmful levels if they're allowed to escape into small spaces. + NHLBI + Oxygen Therapy
What is (are) Polycythemia Vera ?
Polycythemia vera (POL-e-si-THEE-me-ah VAY-rah or VE-rah), or PV, is a rare blood disease in which your body makes too many red blood cells.
                
The extra red blood cells make your blood thicker than normal. As a result, blood clots can form more easily. These clots can block blood flow through your arteries and veins, which can cause a heart attack or stroke.
                
Thicker blood also doesn't flow as quickly to your body as normal blood. Slowed blood flow prevents your organs from getting enough oxygen, which can cause serious problems, such as angina (an-JI-nuh or AN-juh-nuh) and heart failure. (Angina is chest pain or discomfort.)
                
Overview
                
Red blood cells carry oxygen to all parts of your body. They also remove carbon dioxide (a waste product) from your body's cells and carry it to the lungs to be exhaled.
                
Red blood cells are made in your bone marrowa sponge-like tissue inside the bones. White blood cells and platelets (PLATE-lets) also are made in your bone marrow. White blood cells help fight infection. Platelets stick together to seal small cuts or breaks on blood vessel walls and stop bleeding.
                
If you have PV, your bone marrow makes too many red blood cells. It also can make too many white blood cells and platelets.
                
A mutation, or change, in the body's JAK2 gene is the major cause of PV. This gene makes a protein that helps the body produce blood cells. What causes the change in the JAK2 gene isn't known. PV generally isn't inheritedthat is, passed from parents to children through genes.
                
PV develops slowly and may not cause symptoms for years. The disease often is found during routine blood tests done for other reasons.
                
When signs and symptoms are present, they're the result of the thick blood that occurs with PV. This thickness slows the flow of oxygen-rich blood to all parts of your body. Without enough oxygen, many parts of your body won't work normally.
                
For example, slower blood flow deprives your arms, legs, lungs, and eyes of the oxygen they need. This can cause headaches, dizziness, itching, and vision problems, such as blurred or double vision.
                
Outlook
                
PV is a serious, chronic (ongoing) disease that can be fatal if not diagnosed and treated. PV has no cure, but treatments can help control the disease and its complications.
                
PV is treated with procedures, medicines, and other methods. You may need one or more treatments to manage the disease. + NHLBI + Polycythemia Vera
What causes Polycythemia Vera ?
Primary Polycythemia
                
Polycythemia vera (PV) also is known as primary polycythemia. A mutation, or change, in the body's JAK2 gene is the main cause of PV. The JAK2 gene makes a protein that helps the body produce blood cells.
                
What causes the change in the JAK2 gene isn't known. PV generally isn't inheritedthat is, passed from parents to children through genes. However, in some families, the JAK2 gene may have a tendency to mutate. Other, unknown genetic factors also may play a role in causing PV.
                
Secondary Polycythemia
                
Another type of polycythemia, called secondary polycythemia, isn't related to the JAK2 gene. Long-term exposure to low oxygen levels causes secondary polycythemia.
                
A lack of oxygen over a long period can cause your body to make more of the hormone erythropoietin (EPO). High levels of EPO can prompt your body to make more red blood cells than normal. This leads to thicker blood, as seen in PV.
                
People who have severe heart or lung disease may develop secondary polycythemia. People who smoke, spend long hours at high altitudes, or are exposed to high levels of carbon monoxide where they work or live also are at risk.
                
For example, working in an underground parking garage or living in a home with a poorly vented fireplace or furnace can raise your risk for secondary polycythemia.
                
Rarely, tumors can make and release EPO, or certain blood problems can cause the body to make more EPO.
                
Sometimes doctors can cure secondary polycythemiait depends on whether the underlying cause can be stopped, controlled, or cured. + NHLBI + Polycythemia Vera
Who is at risk for Polycythemia Vera? ?
Polycythemia vera (PV) is a rare blood disease. The disease affects people of all ages, but it's most common in adults who are older than 60. PV is rare in children and young adults. Men are at slightly higher risk for PV than women. + NHLBI + Polycythemia Vera
What are the symptoms of Polycythemia Vera ?
Polycythemia vera (PV) develops slowly. The disease may not cause signs or symptoms for years.
                
When signs and symptoms are present, they're the result of the thick blood that occurs with PV. This thickness slows the flow of oxygen-rich blood to all parts of your body. Without enough oxygen, many parts of your body won't work normally.
                
The signs and symptoms of PV include:
                
Headaches, dizziness, and weakness
                
Shortness of breath and problems breathing while lying down
                
Feelings of pressure or fullness on the left side of the abdomen due to an enlarged spleen (an organ in the abdomen)
                
Double or blurred vision and blind spots
                
Itching all over (especially after a warm bath), reddened face, and a burning feeling on your skin (especially your hands and feet)
                
Bleeding from your gums and heavy bleeding from small cuts
                
Unexplained weight loss
                
Fatigue (tiredness)
                
Excessive sweating
                
Very painful swelling in a single joint, usually the big toe (called gouty arthritis)
                
In rare cases, people who have PV may have pain in their bones.
                
Polycythemia Vera Complications
                
If you have PV, the thickness of your blood and the slowed blood flow can cause serious health problems.
                
Blood clots are the most serious complication of PV. Blood clots can cause a heart attack or stroke. They also can cause your liver and spleen to enlarge. Blood clots in the liver and spleen can cause sudden, intense pain.
                
Slowed blood flow also prevents enough oxygen-rich blood from reaching your organs. This can lead to angina (chest pain or discomfort) and heart failure. The high levels of red blood cells that PV causes can lead to stomach ulcers, gout, or kidney stones.
                
Some people who have PV may develop myelofibrosis (MY-e-lo-fi-BRO-sis). This is a condition in which your bone marrow is replaced with scar tissue. Abnormal bone marrow cells may begin to grow out of control.
                
This abnormal growth can lead to acute myelogenous (my-eh-LOJ-eh-nus) leukemia (AML), a cancer of the blood and bone marrow. This disease can worsen very quickly. + NHLBI + Polycythemia Vera
How to prevent Polycythemia Vera ?
Primary polycythemia (polycythemia vera) can't be prevented. However, with proper treatment, you can prevent or delay symptoms and complications.
                
Sometimes you can prevent secondary polycythemia by avoiding things that deprive your body of oxygen for long periods. For example, you can avoid mountain climbing, living at a high altitude, or smoking.
                
People who have serious heart or lung diseases may develop secondary polycythemia. Treatment for the underlying disease may improve the secondary polycythemia. Following a healthy lifestyle to lower your risk of heart and lung diseases also will help you prevent secondary polycythemia. + NHLBI + Polycythemia Vera
What causes Childhood Interstitial Lung Disease ?
Researchers don't yet know all of the causes of childhood interstitial lung disease (chILD). Many times, these diseases have no clear cause.
                
Some conditions and factors that may cause or lead to chILD include:
                
Inherited conditions, such as surfactant disorders. Surfactant is a liquid that coats the inside of the lungs. It helps with breathing and may help protect the lungs from bacterial and viral infections.
                
Birth defects that cause problems with the structure or function of the lungs.
                
Aspiration (as-pih-RA-shun). This term refers to inhaling substancessuch as food, liquid, or vomitinto the lungs. Inhaling these substances can injure the lungs. Aspiration may occur in children who have swallowing problems or gastroesophageal (GAS-tro-eh-so-fa-JE-al) reflux disease (GERD). GERD occurs if acid from the stomach backs up into the throat.
                
Immune system disorders. The immune system protects the body against bacteria, viruses, and toxins. Children who have immune system disorders aren't able to fight illness and disease as well as children who have healthy immune systems.
                
Exposure to substances in the environment that can irritate the lungs, such as molds and chemicals.
                
Some cancer treatments, such as radiation and chemotherapy.
                
Systemic or autoimmune diseases, such as collagen vascular disease or inflammatory bowel disease. Systemic diseases are diseases that involve many of the body's organs. Autoimmune diseases occur if the body's immune system mistakenly attacks the body's tissues and cells.
                
A bone marrow transplant or a lung transplant. + NHLBI + Childhood Interstitial Lung Disease
Who is at risk for Childhood Interstitial Lung Disease? ?
Childhood interstitial lung disease (chILD) is rare. Most children are not at risk for chILD. However, some factors increase the risk of developing chILD. These risk factors include:
                
Having a family history of interstitial lung disease or chILD.
                
Having an inherited surfactant disorder or a family history of this type of disorder. Surfactant is a liquid that coats the inside of the lungs. It helps with breathing and may help protect the lungs from bacterial and viral infections.
                
Having problems with aspiration. This term "aspiration" refers to inhaling substancessuch as food, liquid, or vomitinto the lungs.
                
Having an immune system disorder. The immune system protects the body against bacteria, viruses, and toxins. Children who have immune system disorders aren't able to fight illness and disease as well as children who have healthy immune systems.
                
Being exposed to substances in the environment that can irritate the lungs, such as molds and chemicals.
                
Having a systemic or autoimmune disease, such as collagen vascular disease or inflammatory bowel disease. Systemic diseases are diseases that involve many of the body's organs. Autoimmune diseases occur if the body's immune system mistakenly attacks the body's tissues and cells.
                
Undergoing some cancer treatments, such as radiation and chemotherapy.
                
Having a bone marrow transplant or a lung transplant.
                
Certain types of chILD are more common in infants and young children, while others can occur in children of any age. For more information, go to "Types of Childhood Interstitial Lung Disease."
                
The risk of death seems to be higher for children who have chILD and pulmonary hypertension, developmental or growth disorders, bone marrow transplants, or certain surfactant problems. + NHLBI + Childhood Interstitial Lung Disease
What are the symptoms of Childhood Interstitial Lung Disease ?
Childhood interstitial lung disease (chILD) has many signs and symptoms because the disease has many forms. Signs and symptoms may include:
                
Fast breathing, which also is called tachypnea (tak-ip-NE-ah)
                
Labored breathing, which also is called respiratory distress
                
Low oxygen levels in the blood, which also is called hypoxemia (hi-POK-se-ah)
                
Recurrent coughing, wheezing, or crackling sounds in the chest
                
Shortness of breath during exercise (in older children) or while eating (in infants), which also is called dyspnea (disp-NE-ah)
                
Poor growth or failure to gain weight
                
Recurrent pneumonia or bronchiolitis
                
If your child has any of these signs and symptoms, contact his or her doctor. The doctor may refer you to a pediatric pulmonologist. This is a doctor who specializes in diagnosing and treating children who have lung diseases and conditions. + NHLBI + Childhood Interstitial Lung Disease
What are the treatments for Childhood Interstitial Lung Disease ?
Childhood interstitial lung disease (chILD) is rare, and little research has been done on how to treat it. At this time, chILD has no cure. However, some children who have certain diseases, such as neuroendocrine cell hyperplasia of infancy, may slowly improve over time.
                
Current treatment approaches include supportive therapy, medicines, and, in the most serious cases, lung transplants.
                
Supportive Therapy
                
Supportive therapy refers to treatments that help relieve symptoms or improve quality of life. Supportive approaches used to relieve common chILD symptoms include:
                
Oxygen therapy. If your child's blood oxygen level is low, he or she may need oxygen therapy. This treatment can improve breathing, support growth, and reduce strain on the heart.
                
Bronchodilators. These medications relax the muscles around your childs airways, which helps open the airways and makes breathing easier.
                
Breathing devices. Children who have severe disease may need ventilators or other devices to help them breathe easier.
                
Extra nutrition. This treatment can help improve your child's growth and help him or her gain weight. Close monitoring of growth is especially important.
                
Techniques and devices to help relieve lung congestion. These may include chest physical therapy (CPT) or wearing a vest that helps move mucus (a sticky substance) to the upper airways so it can be coughed up. CPT may involve pounding the chest and back over and over with your hands or a device to loosen mucus in the lungs so that your child can cough it up.
                
Supervised pulmonary rehabilitation (PR). PR is a broad program that helps improve the well-being of people who have chronic (ongoing) breathing problems.
                
Medicines
                
Corticosteroids are a common treatment for many children who have chILD. These medicines help reduce lung inflammation.
                
Other medicines can help treat specific types or causes of chILD. For example, antimicrobial medicines can treat a lung infection. Acid-blocking medicines can prevent acid reflux, which can lead to aspiration.
                
Lung Transplant
                
A lung transplant may be an option for children who have severe chILD if other treatments haven't worked.
                
Currently, lung transplants are the only effective treatment for some types of chILD that have a high risk of death, such as alveolar capillary dysplasia and certain surfactant dysfunction mutations.
                
Early diagnosis of these diseases gives children the chance to receive lung transplants. So far, chILD doesn't appear to come back in patients' transplanted lungs.
                
For more information about this treatment, go to the Health Topics Lung Transplant article. + NHLBI + Childhood Interstitial Lung Disease
How to prevent Childhood Interstitial Lung Disease ?
At this time, most types of childhood interstitial lung disease (chILD) can't be prevented. People who have a family history of inherited (genetic) interstitial lung disease may want to consider genetic counseling. A counselor can explain the risk of children inheriting chILD.
                
You and your child can take steps to help prevent infections and other illnesses that worsen chILD and its symptoms. For example:
                
Make hand washing a family habit to avoid germs and prevent illnesses.
                
Try to keep your child away from people who are sick. Even a common cold can cause problems for someone who has chILD.
                
Talk with your child's doctor about vaccines that your child needs, such as an annual flu shot. Make sure everyone in your household gets all of the vaccines that their doctors recommend.
                
Talk with your child's doctor about how to prevent your child from getting respiratory syncytial (sin-SIT-e-al) virus. This common virus leads to cold and flu symptoms for most people. However, it can make children who have lung diseases very sick.
                
Avoid exposing your child to air pollution, tobacco smoke, and other substances that can irritate his or her lungs. Strongly advise your child not to smoke now or in the future. + NHLBI + Childhood Interstitial Lung Disease