HMS Medusa (1801)
 HMS Medusa was a 38-gun 5th rate frigate of the Royal Navy that served in the Napoleonic Wars. Launched on 14 April 1801 she took part in the Action of 5 October 1804 against a Spanish squadron in the River Plate Expedition in 1807 and made several captures of enemy ships before being converted to a hospital ship in 1813. She was broken up in 1816.