In silico toxicology services for nanoparticle risk assessment C. Helma, D. Gebele, M. Rautenberg in silico toxicology gmbh, Basel, Switzerland Contact: support@in-silico.ch. Information: www.in-silico.ch in silico toxicology gmbh - Rastatterstrasse 41 - CH-4057 Basel, Switzerland http://enanomapper.net This project has received funding from the European Union’s Sev- enth Framework Programme for research, tech- nological development and demonstration under grant agreement no 604134. Abstract During the eNanoMapper project in silico toxicologies (IST) public server infrastructure was adapted to the requirements of the eNanoMapper project and augmented with new developments. This poster gives a comprehensive overview of all IST resources developed within eNanoMapper. Each service is presented with a brief description and links to the public interface, source code, documentation and download links for self-contained docker images. lazar lazar[1] is a framework for read-across predictions. Within eNanoMapper lazar was extended with interfaces for the eNanoMapper infrastructure and capabilities to predict nanomaterial toxicities. ▶lazar source code [2] https://github.com/opentox/lazar ▶lazar Ruby gem library https://rubygems.org/gems/lazar ▶lazar issue tracker https://github.com/opentox/lazar/issues ▶lazar methodology and validation https://github.com/enanomapper/ nano-lazar-paper/blob/master/nano-lazar.pdf ▶lazar tutorial https://github.com/opentox/lazar/blob/master/README.md ▶lazar API documentation http://www.rubydoc.info/gems/lazar nano-lazar The nano-lazar GUI provides a public webinterface for nano-lazar models. ▶nano-lazar public webinterface [3] https://nano-lazar.in-silico.ch ▶nano-lazar source code https://github.com/eNanoMapper/nano-lazar ▶nano-lazar Ruby gem library https://rubygems.org/gems/nano-lazar ▶nano-lazar issue tracker https://github.com/eNanoMapper/nano-lazar/issues ▶nano-lazar API documentation http://www.rubydoc.info/gems/nano-lazar ▶nano-lazar dockerized service on Docker Hub https://hub.docker.com/u/insilicotox/nano-lazar nano-lazar-paper Detailed description of nano-lazar methods and validation results [4]. Results can be reproduced by external researchers with the accompanying docker image. ▶Source code for nano-lazar publication (and oral presentations). https://github.com/enanomapper/nano-lazar-paper ▶Manuscript submitted to Frontiers in Pharmacology https://github.com/ enanomapper/nano-lazar-paper/blob/master/nano-lazar.pdf ▶Tutorial for repeating nano-lazar validation experiments https: //github.com/enanomapper/nano-lazar-paper/blob/master/README.md ▶Docker image for inspection and reproduction of validation experiments https://hub.docker.com/r/insilicotox/nano-lazar-paper/ lazar-rest lazar-rest provides an eNanoMapper compatible REST API for the nano-lazar read-across framework. ▶lazar-rest Swagger UI documentation for API visualization and interaction [5] https://enm.in-silico.ch ▶lazar-rest Swagger API deﬁnition ﬁle https://enm.in-silico.ch/api/api.json ▶lazar-rest source code https://github.com/opentox/lazar-rest ▶lazar-rest Ruby gem library https://rubygems.org/gems/lazar-rest ▶lazar-rest issue tracker https://github.com/opentox/lazar-rest/issues ▶lazar-rest API documentation http://www.rubydoc.info/gems/lazar-rest SPARQL endpoint for eNM ontology and data SPARQL query interface for eNanoMapper data and ontologies ▶SPARQL endpoint https://sparql.enanomapper.net/ ▶Documentation http://enanomapper.net/deliverables/d3/20160420_ eNanoMapper_D3.2_Data_Management_System_with_extended_search_ capabilities_FINAL.pdf ▶Docker image https://hub.docker.com/r/insilicotox/ist-enm-virtuoso/ eNM ontology viewer The eNanoMapper ontology viewer visualizes SPARQL query results from eNM ontologies and data. ▶eNanoMapper ontology viewer [6] https://query.enanomapper.net/ ▶eNanoMapper ontology viewer source code https://github.com/enanomapper/enm-ontoviewer ▶eNanoMapper ontology viewer issue tracker https://github.co