Chemical Curation of Lantana camara Emissions across Native and Invaded Habitats Vipin Kumara, Sonali Chauhanb, Manish Kumara, Renu Kumaria, Suresh Babub, and Gitanjali Yadava a. Computational Biology Laboratory, National Institute of Plant Genome Research, Aruna Asaf Ali Marg, New Delhi 110067, India b. School of Human Ecology, Lothian Road, Kashmere Gate 110006, Ambedkar University Delhi Lantana camara is a major threat to biodiversity in many parts of the globe. Chemical profiling is an effective tool to decipher this complex genus, to support ecology. This study compares chemical profiles of Lantana in native and invaded habitats. ØChemical curation led to accurate identification of compounds ØDistinct chemical profiles in native and invaded habitats ØGreater chemical diversity in Invaded Habitats. INTRODUCTION METHODOLOGY SUMMARY & PERSPECTIVES This work has been funded by NIPGR Core funds, Hamied Award from University of for support anCambridge and TIGR2ESS grant. Authors thank Ucam & NIPGR d Infrastructure. 0 2 4 6 8 10 12 14 16 18 20 22 24 26 28 30 32 34 (Z)-3-hexenol n-hexanol alpha-pinene sabinene beta-pinene myrcene alpha-phellandrene delta-3-carene o-cymene limonene 1,8-cineole (e)-beta- ocimene terpinolene linalool camphor alpha-copaene beta-bourbonene beta-cubebene beta-elememe beta-caryophyllene beta-copaene beta-guaiene alpha-humulene (e)-beta-farnesene alloaromadendrene t-muurolene germacrene D alpha-chamigrene alpha-farnesene delta-cadinene germacrene b spathulenol caryophyllene oxide % Area Compounds Chemical profile of Lantana camara var. in Native Range (Venezuela) 0 2 4 6 8 10 12 14 16 18 20 3-hexen-1-ol, (Z) α-pinene camphen Sabinene β-pinene 1-octen-3-Ol myrcene hexanol, ethyl α-phellandrene δ-3-carene α-terpinene p-cymene eucalyptol (E)-ocimene (Z)-ocimene 𝛾-terpinene 4-thujanol terpinolene linalool geranyl nitrile 2-p-menthen-1-ol camphor L-borneol 4-terpineol methyl salicylate α-terpineol 1-verbenone isobutenyl methyl ketone pentanoate,cis-3-hexenyl acetald bicyclogermacrene bicycloelemene δ-elemene α-cubebene cyclosativene α-copaene β-elemene elemene caryophyllene 𝛾-cadinene α-humulene neoalloocimene 𝛾-muurolene germacrene D bicyclogermacrene germacrene A cubebol sesquilavandulol (Z) davanone B davanone D nerolidol,E denderalasin spathulenol humulene oxide β-atlantone isoaromadendrene epoxide germacrene D-4-ol geranyl linalool isomer B guaia-3,9-dien-11-ol, cis- cedreanol lanceol,cis 6-epi-shyobunol farnesol, (2E,6Z) β-davanone-2ol β-chamigrene aromadendrene-4,10-diol thujopsan-2-α-ol longipinanol % Area Compounds Chemical profile of Lantana camara complex in Invaded Range (India) 11.98 25.10 0.59 53.60 3.96 3.57 % Area of Metabolome in Essential oil Alcohol Monoterpene Monoterpene alcohol Sesquiterpene Azulenic sesquiterpenol Not Classified 1.4 30.2 1 62.8 0.80.9 % Area of Metabolome in Essential oil Alcohol Monoterpene Monoterpene alcohol Sesquiterpene Azulenic sesquiterpenol Sesquiterpene oxide Foliar chemical profiles: Leaf samples of Lantana camara complex were collected in the month of March- April 2019 in Delhi (India). Hydro-distillation : For extraction of essential oil profiles using Clevenger assembly for 3-4 hours. Recovery: Pure essential oil yield via anhydrous sodium sulphate and diethylether Chemical profiling via GC-FID and GC-MS instrument Shimadzu QP2010. Bibliometry and Comparative Analysis: Chemical profiles obtained above were compared Venezuelan nativ datasets (Tesch, et. al. 2011). Statistics in R. REFERENCES 1. Love, A., Naik, D., Basak, S. K., Babu, S., Pathak, N., & Babu, C. R. (2009). Variability in foliar essential oils among different morphotypes of Lantana species complexes, and its taxonomic and ecological significance. Chemistry & biodiversity, 6(12), 2263- 2274. 2. Tesch, N. R., Mora, F., Rojas, L., Díaz, T., Velasco, J., Yánez, C., ... & Pasquale, S. (2011). Chemical composition and antibacterial activity of the essential oil of Lantana ØDifficulties to compare com