www.postersession.com g Remote sensing has been used in many environmental studies because of its capacity to provide information rapidly on large and hard-to-reach areas. Recently, many programmes such as ASTER, Landsat and Copernicus Sentinels have provided satellite imagery of both high temporal and spatial resolutions free of charge. These data, combined with fieldworks and geophysical measurement , can lead to the finding of solutions for modern challenges such as climate change, natural hazards and increasing population growth. We used these technologies in a region which is both sensitive to and vulnerable to these phenomena, the karst environment of the Tabular Middle Atlas (TMA) of Morocco, in order to study the vulnerability of its natural water reserves . The TMA of Morocco contains an important water reservoir, located in Liassic carbonate rocks (dolomite and limestone), and used for everyday activities in cities such as Agourai, Fez, El Hajeb, Ifrane and Meknes. Because of its importance and the value it holds in the economy of the region it has been described as château d’eau. The most recent studies conducted in this region show that water quality is deteriorating due to anthropologic activities and natural processes. The present study proposes the use of earth observation, geophysical methods and free available data to map various forms of karst (avens, dolines, poljes...) and fault systems; these are the most fragile hotspots where the water reservoir can be easily penetrated in this karst system, with pollutants infiltrating and reaching groundwater and eventually identify most vulnerable areas. We intend to answer the question related to the part played by each fracture system, in order to find out which one is responsible for the infiltration of surface water and consequently is contributing to the development of sinkholes, and also to find out which system is draining water from the Causse to the basin. The aim of this study is to enhance the understanding of the hydrogeological system of the TMA, to improve the fracture database, to explore the profitability of new methodology combining space technology, applied geophysics and ground-based field work, and to establish a complete picture of vulnerable areas where sinkholes and human activities are degrading the quality of groundwater. There are three priority questions to be answered: -What is the direction of the fault systems involved in water infiltration, and probably led to the development of different karst landforms? -What is the predominant location of the sinkholes responsible for the turbidity and chemicals observed in water springs? -Where are water-soluble substances such as fertilizers, pesticides and herbicides accelerating carbonate dissolution due to human activities? Methods and materials Conclusions A.Muzirafuti1, M. Boualoul 1, G.Randazzo 2 , A. Allaoui1, S. Lanza 2, H. El Ouardi3, H. Habibi3, H. Ouhaddach3 1 Team of applied geophysics, Nat Ress. and Heritage, Dept. of Geology, Fac. of Sciences, University of Moualy Ismail, BP. 11201 Zitoune, Meknes, Morocco 2 Section of Earth Sciences, Dept. of Math and Computer Science, Physical Sciences and Earth Sciences, Univ. of Messina. Via F. Stagno d'Alcontres, 31 98166 - Sant'Agata di Messina, Messina, Italy – 3 Team of tec mapping, Dept. of Geology, Fac. of Sciences, University of Moualy Ismail, BP. 11201 Zitoune, Meknes, Morocco - Synthetic map of various karst landform location Fieldworks conducted in numerous locations around major faults, water springs and on different karst landforms helped us validate remote sensing results. We noticed that a big number of sinkholes are located in fractured carbonate rocks in low laying areas, some of them were identified in agricultural areas filled with basalts or clay sediments. Structural study conducted on carbonate fractures revealed that 37 % represent NE-SW fault system while 22% and 30 % represent Sub-meridian and NW-SE Fault faults systems resp