Wan Shakira Rodzlan Hasani , Shubash Shander Ganapathy , Chong Zhuo Lin , Halizah Mat Riﬁn , Mohammad Nazaruddin Bahari , Muhammad Haikal Ghazali , Noor Aliza Lodz , Muhammad Haﬁzuddin Tauﬁk Ramli , Nur Liana Ab Majid , Jane Ling Miaw Yn , Muhammad Fadhli Mohd Yusoﬀ , Noor Ani Ahmad , Anita Suleiman , Ahmad Faudzi Yusoﬀ , Venugopalan Balan , Sha’ari Ngadiman Institute for Public Health, National Institutes of Health, Ministry of Health Malaysia, Setia Alam, Selangor, Malaysia Selangor State Health Department (JKNS), Ministry of Health Malaysia, Shah Alam, Selangor, Malaysia Disease Control Division, Ministry of Health Malaysia, WP Putrajaya, Malaysia Institute for Medical Research, National Institutes of Health, Ministry of Health Malaysia, Setia Alam, Selangor, Malaysia NMRR-20-720-54598 1. Wold Health Organization. WHO announces COVID-19 outbreak a pandemic - WHO Director-General’s opening remarks at the media briefing on COVID-19- 11 March 2020. Geneva2020 [cited 2020 14 April]. Available from: https://www.who.int/dg/speeches/detail/who-director-gener- al-s-opening-remarks-at-the-media-briefing-on-covid-19---11-march-2020. 2. Ministry of Health Malaysia. Official Portal Ministry of Health Malaysia, Latest COVID-19 Statistic in Malaysia by MOH as at 5:00pm, April 14th: Ministry of Health Malaysia; 2020 [cited 2020 14 April]. Available from: http://ww- w.moh.gov.my/index.php/pages/view/2019-ncov-wuhan. 3. Li B, Yang J, Zhao F, Zhi L, Wang X, Liu L, et al. Prevalence and impact of cardiovascular metabolic diseases on COVID-19 in China. Clinical Research in Cardiology. 2020:1-8. 4. Ruan Q, Yang K, Wang W, Jiang L, Song J. Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China. Intensive care medicine. 2020:1-3. 5. Guan W-j, Ni Z-y, Hu Y, Liang W-h, Ou C-q, He J-x, et al. Clinical characteristics of coronavirus disease 2019 in China. New England Journal of Medicine. 2020. 6. Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavi- rus in Wuhan, China. The Lancet. 2020;395(10223):497-506. 7. Novel CPERE. The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China. Zhonghua liu xing bing xue za zhi= Zhonghua liuxingbingxue zazhi. 2020;41(2):145. 8. COVID-19 Surveillance Group. Characteristics of COVID-19 patients dying in Italy: report based on available data on March 20th, 2020. Rome, Italy: Instituto Superiore Di Sanita; 2020. 2020. 9. Yang J, Zheng Y, Gou X, Pu K, Chen Z, Guo Q, et al. Prevalence of comorbidities in the novel Wuhan coronavirus (COVID-19) infection: a systematic review and meta-analysis. International Journal of Infectious Diseases. 2020. References related to Invasive Ventilatory Support among COVID-19 cases in Selangor, Malaysia P-16 Coronavirus disease 2019 (COVID-19) is an infectious disease caused by a Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). On March 11, 2020, the World Health Organization declared COVID-19 a pandemic1. Malaysia has also not been spared from the pandemic with a total of 4,987 infected people and 82 deaths up to April 14, 2020 2. A number of studies have shown that underlying comorbidities are predictors of severe disease outcome and greatly aﬀect the prognosis of the COVID-19 patients3-4. COVID-19 causes severe acute respiratory syndrome and is often associated with intensive care unit (ICU) admission and subsequent mortality. Identifying the risk factors that predicts severity and outcome of COVID-19 patients early in the presentation would be extremely helpful for clinicians in managing the patients • This is a retrospective study using data collected during COVID-19 outbreak in Selangor, Malaysia. • COVID-19 conﬁrmed cases in Selangor that were notiﬁed up to 13th April 2020 were included into this study. • A positive case of COVID-19 is conﬁrmed based on positive Reverse Transcriptase-Polymerase Chain React