1 Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University, Czech Republic; 2 Department of Statistical Modelling, The Czech Academy of Science, Czech Republic; 3 Department of Geriatrics and Gerontology, 1st Faculty of Medicine, Charles University, Czech Republic Correspondence: jovanabrkic37@gmail.com; gajdosp1@faf.cuni.cz; veronika.kubikova11@gmail.com; jreissigova@seznam.cz; fialovad@faf.cuni.cz Jovana Brkić1, Petra Gajdošová1, Veronika Kubíková1 , Jindra Reissigová2 , Daniela Fialová1,3 Introduction Potentially inappropriate prescribing, including prescribing potentially inappropriate medications (PIMs) and potential prescribing omissions (PPOs), is highly prevalent in older adults.1-7 The aim of our study was to determine the prevalence of cardiovascular (CV) PIM use in older patients admitted to acute care in the Czech Republic. This poster presents preliminary results of in-progress research within Horizon 2020 EuroAgeism project (10 countries, 4500 patients) and relates also to the scientific work of the European INOMED project. Analyses of potentially inappropriate cardiovascular medication use in acutely hospitalized older patients in the Czech Republic Methods The data for this preliminary analysis were collected at two acute care geriatric departments in two bigger cities in the Czech Republic (Brno and Hradec Kralové) from August 2018 to January 2019. Patients admitted to geriatric wards were assessed, excluding subjects severely cognitively impaired (Mini-Mental State Examination, MMSE <10), terminally ill or admitted to the intensive care unit. Data were collected from medical records and interviews with healthcare professionals and patients using a comprehensive instrument. Several scales of interRAI Organization were used for assessment of functional status, namely Depression Rating Scale (DRS), Cognitive Performance Scale (CPS) and ADL and IADL hierarchy scales. Also, other information related to diseases, symptoms, medication use, utilization of healthcare services, and satisfaction with care provision were collected. CV PIM use was assessed by trained researchers using several consensus‐based explicit criteria, namely Screening Tool of Older Person’s Prescriptions (STOPP)3, Screening Tool to Alert doctors to the Right Treatment (START)3, EU(7)-PIM list4 and Beers criteria 20195. In total, 99 individual criteria were applied. The study was approved by the Ethical Committee of the Charles University, Faculty of Pharmacy and by Ethical Committees of participating acute care hospitals. Results Of the 288 patients assessed, 57 % (164) were women. The patient age distribution was as follows: 35.8 % were 65-74 years, 35.4 % were 75-84 years, 27.1 % were 85-94 years and 1.7 % were 95 years and older. Overall, 77.6 % of patients were exposed to CV PIMs. The highest prevalence of CV PIMs was identified by START criteria (63.2 % of older patients), followed by EU(7)-PIM list (31 %). The lowest prevalence was documented using Beers criteria 2019 (16.1 %). (see Tables 1,2,3) Conclusion The use of CVS PIMs is highly prevalent in older hospitalized patients in the Czech Republic. The results varied according to different criteria and the highest prevalence was identified by START criteria. We intend to conduct further analyses using data of the whole Horizon EuroAgeism H2020 project when data collection is finalized in December 2020. For more information on Horizon 2020 EuroAgeism and INOMED projects visit websites:https://portal.faf.cuni.cz/Projects/Euroageism-Project/; https://portal.faf.cuni.cz/Careers/InoMed- Researcher-201910/ Tables 1) Prevalence of patients with 1+ CV PIM 2) Prevalence of patients using 0,1,2,3,3+ CV PIMs 3)Top 3 most often used CV PIMs Literature cited 1.O’Connor et al. Drugs Aging. 2012. 2. Fialová et al. Eur J Clin Pharmacol. 2019. 3. Fialová et al. J Am Med Assoc. 2005. 4. Gallagher et al. Eur J Clin Pharmacol. 2011. 5. Morin et al. J Am Med Dir Ass