Premise: In the preamble to the final rule, the FDA addresses the various issues raised by commenters in this area, including the preemption of State and local laws which are different from or in addition to the requirements under the final rule; whether there is an infringement on the States' right to regulate tobacco and businesses within the State and protect the health of its citizens; the allocation of a State's resources and the rule's possible impact on the States' economies.

Hypothesis: The FDA addresses the various issues raised by commenters in this area.
Relation: entailment