Question: I have 3 different Windows 10 virtual desktops. When the computer starts up, I want python to load all of my applications in the different virtual desktops.  Right now I can only start things in Desktop 1. How do I tell python to launch an app but in Desktop 2 and 3?  I'm using python 3.6.

Answer:  How do I tell python to launch an app but in Desktop 2 and 3?  This can be achieved by launching your applications with subprocess.Popen(), then changing virtual desktop by calling GoToDesktopNumber() from VirtualDesktopAccessor.dll with the help of ctypes, and launching your applications again. Tested with 64-bit Windows 10 Version 10.0.18363.720. VirtualDesktopAccessor.dll by Jari Pennanen exports the functions a part of the mostly undocumented (by Microsoft) Virtual Desktop API. Put the dll in the current working directory. import ctypes, time, shlex, subprocess def launch_apps_to_virtual_desktops(command_lines, desktops=3): virtual_desktop_accessor = ctypes.WinDLL("VirtualDesktopAccessor.dll") for i in range(desktops): virtual_desktop_accessor.GoToDesktopNumber(i) time.sleep(0.25) # Wait for the desktop to switch for command_line in command_lines: if command_line: subprocess.Popen(shlex.split(command_line)) time.sleep(2) # Wait for apps to open their windows virtual_desktop_accessor.GoToDesktopNumber(0) # Go back to the 1st desktop command_lines = r""" "C:\Program Files (x86)\Google\Chrome Beta\Application\chrome.exe" "C:\Program Files (x86)\Adobe\Acrobat Reader DC\Reader\AcroRd32.exe" "C:\StudyGuide.pdf" "C:\Program Files\Mozilla Firefox\firefox.exe" "C:\Program Files\VideoLAN\VLC\vlc.exe" """.splitlines() launch_apps_to_virtual_desktops(command_lines)  The time.sleep() calls are needed because Windows doesn't change virtual desktops instantly (presumably because of animations), and to give the processes time to create windows. You might need to tweak the timings. Note that some applications only allow one instance/process, so you can't get multiple separate windows for each virtual desktop (e.g. Adobe Reader with default settings).  Another strategy I tried was launching the applications, sleeping for a bit to allow the windows to be created, then calling MoveWindowToDesktopNumber() to move every window created by the new processes to different virtual desktops. The problem with that is, for applications like Chrome or Firefox, the new process is immediately closed if an existing process already exists, so it doesn't move the new windows (which actually belong to another, older process) to another desktop. import ctypes, time, shlex, subprocess from ctypes.wintypes import * from ctypes import windll, byref def get_windows(pid): current_window = 0 pid_local = DWORD() while True: current_window = windll.User32.FindWindowExA(0, current_window, 0, 0) windll.user32.GetWindowThreadProcessId(current_window, byref(pid_local)) if pid == pid_local.value: yield current_window if current_window == 0: return def launch_apps_to_virtual_desktops_by_moving(command_lines, desktops=3): virtual_desktop_accessor = ctypes.WinDLL("VirtualDesktopAccessor.dll") for i in range(desktops): pids = [] for command_line in command_lines: if command_line: args = shlex.split(command_line) pids.append(subprocess.Popen(args).pid) time.sleep(3) for pid in pids: for window in get_windows(pid): window = HWND(window) virtual_desktop_accessor.MoveWindowToDesktopNumber(window, i) command_lines = r""" "C:\Program Files (x86)\Google\Chrome Beta\Application\chrome.exe" "C:\Program Files (x86)\Adobe\Acrobat Reader DC\Reader\AcroRd32.exe" "C:\StudyGuide.pdf" "C:\Program Files\Mozilla Firefox\firefox.exe" "C:\Program Files\VideoLAN\VLC\vlc.exe" """.splitlines() launch_apps_to_virtual_desktops_by_moving(command_lines)