## 2 Materials and Methods
Between the 1 RM shoulder press, deadlift, and squat there was a 10-15 min rest period when participants were allowed to walk, perform light dynamic movements, and consume small amounts of water [16]. After determining 60% of 1 RM, participants performed twothrofe familiarization sessions on separate days before starting the formal training sessions. Sessions 3-8: Before the start of the training session, every participant did pre-stretching and warm up for 5-10 min. Participants performed six RT sessions on separate days in a randomized order (Table 1), each at the same time of day, which consisted of the shoulder press, deadlift, and squat exercises at 60 % of 1 RM, three sets of 10 repetitions at a cadence of 1.5 s up and 1.5 s down using an audible metronome to control for potential variations in the lifting cadence of participants. Between each set, there was 2 min rest period and 8 min rest interval between each type of exercise. A minimum of 24-48 h of a rest interval between each resistance training session was included. The oxygen consumption (VO2) was recorded during each training session through a breath-by-breath analysis using Cortex Metalyzer 3B while wearing a mask. Before beginning training, participants were provided with an explanation of the Borg rate of perceived exertion scale (6-20; RPE). The VO2, RER, and HR were recorded for a total of 52:30 min for each training session, including the resting (10 min), exercise (30 s \(\times\) nine sets), rest after exercise (2-8 min), and recovery (10 min) periods. Blood pressure (systolic and diastolic-SBP and DBP), RPE, and blood lactate (BL) were recorded before the start of \begin{table}
\begin{tabular}{c c c c c} \hline \hline \multirow{2}{*}{**Exercise Order**} & \multirow{2}{*}{
\begin{tabular}{c} **Training** \\ **Sessions** \\ \end{tabular} } & \multicolumn{4}{c}{**Exercises**} \\ \cline{3-5}  & & **1** & **2** & **3** \\ \hline \multirow{2}{*}{Sequence 1} & Session 1 & Shoulder press & Deadlift & Squat \\ \cline{2-5}  & Session 2 & Shoulder press & Deadlift & Squat \\ \hline \multirow{2}{*}{Sequence 2} & Session 3 & Deadlift & Shoulder press & Squat \\ \cline{2-5}  & Session 4 & Deadlift & Shoulder press & Squat \\ \hline \multirow{2}{*}{Sequence 3} & Session 5 & Squat & Shoulder press & Deadlift \\ \cline{2-5}  & Session 6 & Squat & Shoulder press & Deadlift \\ \hline \hline \end{tabular} Each exercise was performed with dumbbells on a separate day total consisting of six training sessions.  
\end{table} 
Table 1: Order of exercise sequences (interval resistance training). training and immediately after each exercise using a portable Omron sphygmomanometer (Omron Healthcare, Inc., IL, USA), RPE scale, and portable THE EDGE Blood Lactate Monitoring System (ApexBio, Hsinchu, Taiwan). For blood lactate monitoring, blood samples were collected and asepsis was performed with 70% ethyl alcohol on the distal fingertips of the left or right hand. The puncture was performed using disposable lancets, and a suspended drop of blood was applied to a lactate test strip for analysis on a lactate meter [12] (Figure 2). Outcome measures: The recorded variables were VO\({}_{2}\) (ml/kg/min), VO\({}_{2}\) (L/min), METs, RER, HR (beats per min (bpm)), SBP (mmHg), DBP (mmHg), BL (mg/dl), and RPE score. For each exercise of six sessions, the METs, RER, and HR during exercise, rest, and recovery periods while blood pressures, RPE, and BL recorded during rest are presented as average values. Statistical analysis: Raw data from the Cortex metalyzer were exported and processed in Excel software. For statistical analysis, SPSS software (IBM SPSS Statistics vs. 19, Armonk, NY, USA) was used. The normality of the data was evaluated by a bell-shaped histogram. Study demographics are presented in the form of descriptive statistics (Table 2). Our study data were continuous repeated measures, so for modeling MET with multiple repeated variables, generalized estimating equations (GEE) [17] with backward deletion method were used in SPSS.