# Industrial Mass Production of Platelet Dry Powder
## 4 Discussion
Studies have shown favorable effects among animal models when using PRP from different species in allogeneic or heterogeneous treatments; examples include the use of canine PRP gel on wound healing among rabbits [30], the use of canine PRP on treating skin wounds among cats [31], the extraction of GFs from equine blood on repairing cartilage defects among rabbits [18], the use of equine PRP treatments to accelerate healing in rabbits with surgically induced skin wounds [32], and human PRP to induce apoptosis in rabbit chondrocytes [33]. These examples demonstrate the applicability of platelets and GFs between species. Successful examples of cross-species applications of platelets and GFs allow us to find versatile and effective platelet and GF applications through in-depth research, contributing to the further development of regenerative medicine. In addition to further research into the role of GFs in autologous repair and regeneration, a new research direction will be their cross-species applications and effects. Numerous studies have reported the application of freeze-dried PRP or PRF in areas such as wound healing [34], bone repair [18], and ophthalmic diseases [35]. Compared to fresh autologous PRP, the shelf-life of freeze-dried growth factors is significantly longer, typically ranging from 12 to 18 months [18], as opposed to only 4 to 8 h or even less for autologous PRP. Recent research has confirmed that freeze-dried growth factors significantly enhance the healing of induced wounds in dogs [36]. The technique of freeze-drying is a commonly used method to improve the stability of tissue regeneration proteins and prolong their preservation [35]. This technique not only enhances the stability and storage potential of proteins but also retains their original biological activity. These properties make freeze-dried proteins an ideal choice for therapeutic applications. Therefore, based on these findings, the platelet dry powder we have prepared also holds potential for application in these fields, demonstrating its value in promoting wound healing and tissue regeneration. This further underscores the clinical significance and potential application scope of our research findings. Using pig blood to mass-produce platelet dry powder can yield many benefits. In addition to a steady supply, there are also economic benefits--a byproduct of the slaughter process can be transformed into high-value biomedical products, increasing the economic value of pig blood and reducing raw material costs. Platelet dry powder can also be preserved for a long time. At normal temperatures, preparing platelet dry powder from pig blood can ensure long-term storage and immediate availability when necessary, reducing the reliance on fresh blood and enhancing the convenience of platelet dry powder for medical centers and professionals in unseen ways. Furthermore, a heightened environmental consciousness has increased the appeal of preparing platelet dry powder from pig blood. Instead of viewing pig blood as waste, this type of resource recycling contributes to environmental protection and complies with modern concepts of a green, circular economy. Last, as pig blood is rich in platelets and GFs, platelet dry powder prepared from such sources is high in quality and concentrations of both properties. Therefore, using pig blood to prepare platelet dry powder is undoubtedly a strategy with many advantages that will promote its widespread usage in biomedicine.