###### Abstract  
The issue of reducing spatial disparities in access to healthcare is one of the most important healthcare planning issues that policy makers and planners investigate and consider as a key focus until present time. A healthcare system that meets the requirements of availability and affordability will be useless if the spatial accessibility to healthcare is not provided to all equally. Therefore, this study aims to identify and analyze spatial disparities in access to healthcare centers in Jeddah, Saudi Arabia. The two-step floating catchment area (2 SFCA) method was used to measure spatial accessibility of healthcare centers based on the travel time threshold (i.e., 30-min drive time in this study). The GIS technology was used to execute the 2 SFCA method. A geodatabase, which includes the population districts, locations of healthcare centers, and road network, was created. Some procedures were performed within the road network database to set the travel time that is considered as an essential step to compute the origin-destination (OD) cost matrix. The OD matrix was later used as the source for calculating provider-to-population ratios and the spatial accessibility scores for population districts. The results of the study revealed spatial disparities in access to healthcare centers in Jeddah city. The majority of the Jeddah population (i.e., 97.51%) have accessibility to healthcare centers, but with disparate levels. The central districts have a higher access score compared to the rest of the city's districts. Most districts that do not have accessibility to healthcare centers are concentrated in the southeast of the city. The results can help local health planners improve spatial equity in access to healthcare centers through giving the less-served districts a priority when allocating future healthcare centers in Jeddah city. countries, have been seeking to overcome this challenge by providing an equitable and efficient healthcare system [5; 8; 9; 10]. However, the issue of reducing spatial access disparities to healthcare is one of the most important issues of healthcare planning that planners and policy makers investigate and consider as a key focus until the present time. The challenge is how to ensure that spatial accessibility to healthcare is given to all individuals equitably [6; 11; 12]. The spatial access disparities to healthcare in urban contexts resulted from several factors. First, the rapid and continuous increase in the population and urban growth of cities. Second, the urbanization of poverty, where people living under conditions of poverty suffer from health burdens that should not be underestimated. The third factor is the lack of government expenditure on healthcare provision. Governments try to provide healthcare services to all equally, but, in contrast, they face difficulties spending on healthcare sector development, which leads to an inability of healthcare systems to meet the growing demand for healthcare [4; 10]. The fourth factor is structural barriers, such as a limited availability of transportation options, a lack of road network, and poor road conditions. These barriers can prevent or limit access to healthcare providers, which may contribute to creating more spatial disparities [13; 14]. Overall, availability of preceding factors contributes to creating spatial inequality in access to healthcare, thus causing the emergence of some communities spatially facing a difficulty of accessing healthcare in urban areas compared to other communities that have perfect access to healthcare [9; 10]. Spatial disparities in access to healthcare can be identified and analyzed by measuring the spatial accessibility to healthcare that researchers have extensively investigated recently [15; 16; 17; 18]. Measurement of spatial accessibility estimates the movement opportunity between two different destinations and calculates the degree of relative difficulty that individuals face in accessing healthcare [19].