# Advances in Wearable Smart Chemical Sensors for Health Monitoring
## 3 Conclusions and Outlook  
This review provides a concise overview of the latest advancements in five types of wearable smart chemical sensors for health monitoring. While a variety of commercial health monitoring sensors are available on the market, they often face significant limitations,  
Figure 6: Wearable chemical sensors based on energy storage devices. **(a)** Schematic of a supercapacitor-based gas detection system. **(b)** Schematic of a printable fabrication procedure and system operation mechanism for a self-powered smart sensor system. **(c)** Hybrid self-powered power textile system. **(d)**Self-powered textile fabric using weaving under motion conditions. **(e)** The preparation process of self-healable hydrogel electrolyte with high-performance supercapacitors. **(f)** Self-healing process of self-healable hydrogel electrolyte. such as complex structures, high costs and cumbersome operation, which hinder their widespread adoption in practical scenarios. In contrast, wearable chemical sensors offer advantages including convenience, real-time monitoring and continuous detection, making them highly promising for applications in healthcare, environmental monitoring and safety assessment. Notwithstanding their inherent potential, the extensive dissemination and application of wearable smart chemical sensors in the domain of health monitoring are confronted with a multiplicity of critical issues that warrant further in-depth consideration. In order to surmount these challenges, the following aspects are deserving of particular and meticulous attention: (1) Interference resistance and signal stability: Variations in external environmental factors, such as humidity and temperature, can severely impact signal output stability, thereby reducing the reliability and consistency of detection results. This issue can be mitigated by enhancing device encapsulation or employing materials and components that are less sensitive to environmental changes. (2) Comfort and breathability: Non-stretchable, rigid and non-breathable materials can significantly compromise wearing comfort, limiting prolonged usage and negatively affecting user experience. To address this, lightweight, breathable, and skin-friendly materials should be prioritized to enhance user comfort. (3) Equipment Durability: Prolonged health monitoring requires that equipment has the ability to operate for long periods of time, which places stringent demands on the durability of equipment materials. Solutions include the use of wear-resistant and self-repairing materials, the incorporation of protective coatings, and the optimization of structural design. In summary, while wearable chemical sensors demonstrate immense potential for health monitoring applications, their development is hindered by significant technical and practical challenges. Future research should focus on developing skin-friendly, flexible materials and structural optimization to minimize wear and increase durability. In addition, relying on advanced packaging technology also solves the problem of environmental interference, thus ensuring the reliability and stability of sensor performance. Addressing these challenges is essential to realize the potential of wearable smart chemical sensors for health monitoring applications. Conceptualization, methodology, investigation, analysis, writing--original draft and visualization, N.B. and W.Y. ; writing--review and editing, W.W.; conceptualization, methodology and writing--review, C.C. and P.C. ; All authors have read and agreed to the published version of the manuscript. Not applicable. * [PERSON] et al. (2019) [PERSON]; [PERSON]; [PERSON] [PERSON]; [PERSON]; [PERSON]; [PERSON] Electrochemical micro analytical device interfaced with portable potentiostat for rapid detection of chlorpyrifos using acetylcholinesterasecholinesteraseerase conjugated metal organic framework using Internet of things. _Sci. Rep._**2019**, \(9\), 19862. [CrossRef] [PubMed]
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