# Hyperlipidemic Rabbit Models for Anti-Atherosclerotic Drug Development
## Abbreviations
(1976)_ [PERSON]; [PERSON]; [PERSON] Competitive inhibition of 3-hydroxy-3-methylglutaryl coenzyme a reductase by ML-236A and ML-236B fungal metabolites, having hypocholesterolemic activity. _FEBS Lett._**1976**, _72_, 323-326. [CrossRef]* [PERSON] et al. (1979) [PERSON]; [PERSON] [PERSON]; [PERSON] [PERSON]; [PERSON] [PERSON] Effects of ML-236B on cholesterol metabolism in mice and rats: Lack of hypocholesterolemomic activity in normal animals. _Biochim. Biophys. Acta (BBA)/Lipids Lipid Metab._**1979**, _575_, 266-276. [CrossRef]
* [PERSON] (1980) [PERSON] Regulation of cholesterol synthesis, as focused on the regulation of HMG-CoA reductase. _Seikagaku_**1980**, _52_, 1033-1049. [PubMed]
* [PERSON] et al. (1981) [PERSON]; [PERSON]; [PERSON] [PERSON]; [PERSON] [PERSON]; [PERSON] [PERSON]; [PERSON] [PERSON]; [PERSON] [PERSON]; [PERSON] [PERSON] Hypolipidemic effects of CS-500 (ML-236B) in WHHLL-rabbit, a heritable animal model for hyperlipidemia. _Atherosclerosis_**1981**, _38_, 27-31. [CrossRef]
* [PERSON] et al. (1979) [PERSON]; [PERSON] [PERSON]; [PERSON] [PERSON]; [PERSON]; [PERSON] Hypolipidemic effects in dogs of ML-236B, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme a reductase. _Atherosclerosis_**1979**, _32_, 307-313. [CrossRef]
* [PERSON] et al. (1979) [PERSON]; [PERSON]; [PERSON]; [PERSON] Hypolipidemic effects in monkeys of ML-236B, a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase. _Lipids_**1979**, _14_, 585-589. [CrossRef]
* [PERSON] (1999) [PERSON] Drug Treatment of Lipid Disorders. _N. Engl. J. Med._**1999**, _341_, 498-511. [CrossRef]
* [PERSON] et al. (1994) [PERSON]; [PERSON]; [PERSON] [PERSON]; [PERSON]; [PERSON]; [PERSON]; [PERSON]; [PERSON]; [PERSON]; [PERSON]; et al. Antiatherosclerotic activity of inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase in cholesterol-fed rabbits: A biochemical and morphological evaluation. _Atherosclerosis_**1994**, _111_, 127-142. [CrossRef]
* [PERSON] et al. (1988) [PERSON] [PERSON]; [PERSON] [PERSON]; [PERSON] [PERSON]; [PERSON] [PERSON]; [PERSON] [PERSON]; [PERSON] [PERSON]; [PERSON] [PERSON]; [PERSON] Preventive effect of pravastatin sodium, a potent inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase, on coronary atherosclerosis and xanthoma in WHHLL rabbits. _Biochim. Biophys. Acta (BBA)/Lipids Lipid Metab._**1988**, _960_, 294-302. [CrossRef]
* [PERSON] et al. (1982) [PERSON]; [PERSON]; [PERSON]; [PERSON] The effects of mevinolin on serum cholesterol levels of rabbits with endogenous hypercholesterolemia. _Atherosclerosis_**1982**, _44_, 41-48. [CrossRef]
* [PERSON] (1981) [PERSON]; [PERSON]; [PERSON] Influence of mevinolin on experimental atherosclerosis in rabbits. _Pharmacol. Res. Commun._**1981**, _13_, 921-926. [CrossRef]
* [PERSON] et al. (1989) [PERSON]; [PERSON]; [PERSON]; [PERSON]; [PERSON] [PERSON]; [PERSON] [PERSON]; [PERSON] [PERSON] Preventive effect of MK-733 (simvastatin), an inhibitor of HMG-CoA reductase, on hypercholesterolemia and atherosclerosis induced by cholesterol feeding in rabbits. _Jpn. J. Pharmacol._**1989**, _49_, 125-133. [CrossRef] [PubMed]
* [PERSON] et al. (1995) [PERSON]; [PERSON]; [PERSON]; [PERSON] Comparative effects of HMG-CoA reductase inhibitors on apo B production in the casein-fed rabbit: Atorvastatin versus lovastatin. _Atherosclerosis_**1995**, _115_, 173-180. [CrossRef]
* [PERSON] et al. (2001) [PERSON]; [PERSON] [PERSON]; [PERSON] [PERSON]; [PERSON] [PERSON]; [PERSON] [PERSON]; [PERSON] [PERSON]; [PERSON] [PERSON]; [PERSON] [PERSON]; [PERSON] [PERSON] Anti-oxidative properties of fluvastatin, an HMG-CoA reductase inhibitor, contribute to prevention of atherosclerosis in cholesterol-fed rabbits. _Atherosclerosis_**2001**, _154_, 87-96. [CrossRef]
* [PERSON] et al. (2004) [PERSON]; [PERSON]; [PERSON]; [PERSON] [PERSON]; [PERSON]; [PERSON]; [PERSON] [PERSON]; [PERSON] [PERSON]; [PERSON] [PERSON]; [PERSON]; et al. A new HMG-CoA reductase inhibitor, pitavastatin remarkably retards the progression of high cholesterol induced atherosclerosis in rabbits.