## 2 Results and Discussion  
The first step was the accurate configuration of the MW prototype reactor (Ethos LEAN, Milestone; Figure 1). A dedicated vessel (rotating drum; see Figure 1 on the right) was filled with dried _Cannabis_ infloresences, closed and placed inside the oven cavity. The vessel output was connected to three sequential glass bubblers (identified as 1, 2 and 3 from the closest to the MW oven) through PTFE tubes with sealed connections, which were placed outside the oven and connected to a mild vacuum to help air flow from the reactor (Figure 1 on the left). Each bubbler was filled with olive oil (100 mL, Ph. Eur. grade). The fast MW-assisted decarboxylation of acidic cannabinoids was carried out at 120 \({}^{\circ}\)C (30 min) with vessel rotation, as described by [PERSON] et al. [42]. During this process, the volatiles coming from the rotating drum were trapped in the oil fractions (F1, F2 and F3, and no odor was perceived outside the MW cavity. After a cooling step, the drum was removed from the oven and the plant matrix was recovered and used for cannabinoid extraction, while the three oil fractions were mixed and diluted to 1 L with fresh olive oil (Mix F1 \(\div\) 3 dil.). Decarboxylated infloresences were placed in a glass reactor together with the prepared olive oil (matrix/solvent ratio 1:10) and heated under MW irradiation with stirring at 100 \({}^{\circ}\)C for either 30 min (Ext. 100) or at 60 \({}^{\circ}\)C for 30 min using a cold finger, maintained at 8 \({}^{\circ}\)C and directly inserted into the oil (Ext. 60). At the end of the final cooling step, the oil samples were filtered under vacuum to recover the extract in oil. For all samples (F1, F2, F3, Mix F1 \(\div\) 3 dil., Ext. 60 and Ext. 100), an aliquot of 10 mL was taken for analysis. As outlined in the first paragraph, HS-SPME has been considered the analytical extraction technique of choice for _Cannabis_-based preparations and products in recent years [25; 28; 29]. Our protocol is based on Merck technical reports [31; 32]. A DVB/CAR/PDMS fiber assembly (1 cm, 50/30 \(\upmu\)m film thickness, Supelco, Bellefonte, PA, USA) was used with the same injector and detector temperatures, oven ramp and mass parameters being applied (see Section 3). However, a Mega-5 MS column, as in [PERSON] et al. [39], an equilibration time of 10 min and an extraction time of 40 min were used as SPME parameters, as in the Aparicio-Ruiz method for the analysis of volatile compounds in olive oils [43]. The preparation of the samples and internal standard solutions (IS) was also carried out following the detailed protocol in this article, using 2-undecanol as the IS (2.0 \(\pm\) 0.2 mg/g in olive oil) and by adding 0.2 g of IS solution to 2.8 g of the aromatic oil samples. The infloresances were ground in a laboratory blender under liquid nitrogen, and samples were then prepared for SPME analysis by adding 0.2 g of IS solution to 100 mg of plant material. Details are reported in the Section 3. A blank with the olive oil used for trapping the volatiles and cannabinoid extraction was prepared and analyzed under the same conditions to verify that its oil aromatic profile did not interfere with the retention times of the IS (14.93 min, Figure 2) and _Cannabis_ terpenes (between 4 and 9 min for monoterpenes, 9 and 12 min for monoterpenoids, 17 and 21 min for sesquiterpenenes and 22 and 24 min for sesquiterpenoids; Figure 2 and Table 1). Figure 1: Ethos LEAN MW oven configuration for the capture of _Cannabis_ terpenes in olive oil (Milestone Srl). The infloreserences showed a total amount of terpenes and terpenoids equal to 91,324.74 \(\pm\) 2774.36 mg/kg dry matrix (Table 1), which is quite similar to the value found in Bedrocan(r) (-111,400 mg/kg), while higher than that observed in Bediol(r) (-64,000 mg/kg) (29).