## 2 Materials  
The years of this study are 2014, 2015, 2016, and 2017. To be able to carry it out, data on pollen concentrations in the atmosphere, concentrations of atmospheric pollutants, and episodes of attention of 2 types of allergic diseases have been collected. Pollen data have been supplied by the Palinocam Network of the Regional Ministry of Health of the CAM [20]. In 1992, the Regional Commission for the Prevention and Control of Asthma was created from the Regional Program of the same name to improve the quality of life of patients with asthma in the CAM and, to this end, it began to develop its activity in the form of 4 areas of work. One of them consists of epidemiological surveillance, which initially aimed to know the prevalence and incidence of asthma and its evolution in the territory of the Autonomous Community. Another area of work is environmental surveillance, whose aim is to detect the evolution of atmospheric pollutants, to know the types of pollen and their distributions in time and space, and to disseminate these pollen data to allergists, pulmonologists, pediatricians, emergency services, primary care teams, and allergic patients [14]. The air pollutant data have been provided by the Air Quality Network of the Regional Ministry of Environment, Spatial Planning and Sustainability of the CAM, and by the Air Quality Network of the Madrid City Council [20]. These two data types are collected daily and obtained from measurements made by sampling stations. They have been described in detail in the abovementioned study, in which the correlation between both factors was also analyzed. Thus, in that study, the six types of tree pollen and the six atmospheric pollutants are analyzed, including their mean values, standard deviation, and coefficient of variation of both independent variables. In addition, in the case of the pollen types, their percentage of representation concerning the total pollen collected in the 11 stations of the Palinocam Network is specified. The geographical location and nomenclature of the measurement stations of the two types of variables, the description of the arboreal biodiversity, and the analysis of the benefits of its presence in the CAM are also noted [20]. As for the data on episodes of care, also collected daily, they have been collected by primary care consultations from the Health Centers located in the 11 areas of the Palinocam Network (Table 1) and supplied by the General Subdirectorate of Epidemiology of the Health Department of the Regional Ministry of Health of the CAM. \begin{table}
\begin{tabular}{l l} \hline \hline \multicolumn{1}{c}{**Palinocam Network Stations**} & \multicolumn{1}{c}{**Nearest Health Centers**} \\ \hline
**Alcalá de Henares** & Carmen Calzado (505 m), Reyes Magos (1020 m), Maria de Guzman (1090 m), Manuel Merino (1100 m), Puerta de Madrid (1130 m), Luis Vives (1180 m), Nuestra Señora del Pilar (1550 m), Juan de Austria (1630 m), La Garena (2140 m), Miguel de Cervantes (2800 m). \\ \hline
**Alcobendas** & Marqués de Valdavia (630 m), Valdelasfuentes (880 m), La Chopera (1130 m), Miraflores (1420 m), Arroyo de la Vega (1890 m). \\ \hline
**Aranjuez** & Aranjuez (0 m), Las Olivas (1400 m). \\ \hline
**Coslada** & Doctor Tamames (290 m), El Puerto (816 m), Valleaguado (1930 m), Jaime Vera Coslada (2115 m), Ciudad San Pablo (2137 m). \\ \hline \hline \end{tabular}
\end{table} 
Table 1: Names of the CAM Health Centers from which the data on episodes of care for the allergic pathologies analyzed in this study were obtained. These centers were selected within the areas of influence of the 11 stations of the Palinocam Network. The approximate distances of each Health Center from the corresponding Palinocam Network station, measured with the Google Earth geographic information system, are shown in parentheses. The areas corresponding to the capital of Madrid have been shaded in light blue. The episodes of care for rhinitis and allergic conjunctivitis refer to the number of persons consulted daily about these pathologies.