## 3 Results
### Phase 2. System Design  
Based on the analysis of FGI results, the main menu of the application was designed to comprise health management, laboratory test results, medications, meals, concomitant medications, adverse reactions, questionnaires, and My Alarm. To optimize usability, all menu items were displayed on the main screen, which was the first screen after login [27]. The design of the information architecture of the application is schematically illustrated in Figure 2a, as applied to the menu in needs and the procedures of clinical trials.  
\begin{table}
\begin{tabular}{c c c} \hline \hline
**No.** & **Needs** & **Details** \\ \hline \multirow{2}{*}{1} & Checking for side & A function for recording side effects and adverse reactions is required. \\  & effects and & (This information is currently recorded in the comment section because there is no separate section for recording it) \\  & adverse reactions & \\ \hline \multirow{2}{*}{2} & Concomitant & Taking photos and uploading concomitant drug function information is required to check drug relationships. \\  & drug check & \\ \hline \multirow{3}{*}{3} & Remote feedback & In addition to the traditional method of calling or texting the Clinical Research Coordinator, a function to give feedback to the patient based on the data recorded in the application is required (e.g., by analyzing a chat message). \\  & function function & \\ \hline \multirow{2}{*}{4} & Data sharing with the & A function to share data such as laboratory test results, doctors’ feedback, and a brief history of the patient, from the hospital system, is required. \\  & hospital system & \\ \hline \multirow{2}{*}{5} & Application menu & Separate menus to check medication, diet, concomitant medications, and adverse reactions \\  & & are required \\ \hline \multirow{2}{*}{6} & Standard form use & The form of the application should be based on the standard form currently used in the clinical trial center. \\ \hline \multirow{2}{*}{7} & Design requirements & The design should be based on the target audience of users under 60 years of age. \\ \hline \hline \end{tabular}
\end{table}
Table 1: Collected needs for the real-time clinical trial monitoring system.  
The rows of the information architecture of the main screen are ordered according to the general procedures of clinical trials, such as recording symptoms, checking test results, entering medicine records, etc. Columns of the information architecture were organized by listing the contents to be recorded in each menu.  
A wireframe with more detailed descriptions of buttons and functions was created, as shown in Figure 2b. The mobile application screen was designed to be intuitively understandable, as shown in the lower-left panel. The global navigation bar is located at the top of the screen, and management items such as weight, blood pressure, daily steps, and blood sugar level are displayed in a single row for easy recognition. Each item can also have a separate graph display with the most recent data. The value of each item can be manually entered by the user, and data is linked with the Samsung Health app, so when using a wearable device or another measuring device that works with the Samsung Health  
Figure 2: (**a**) Information architecture; (**b**) Wireframe. ECG, electrocardiogram. BMI, body mass index.  
app, it can also be entered through the device. The user interface suggested for the trial version application was developed by adopting the CRPs' feedback to remove unnecessary text and medical terms to make the screen less complicated and to include pictograms for easy understanding for non-professional trial participants.