## 3 Results
### Segmentation of the Gel-Pad Region with GAC and DRLSE Methods (TLSM Approach)  
In the following tables, the highest values for the F-measure median are reported. Table 4 contains information of transverse images; Table 5 contains information of sagittal images segmented with the GAC method and Table 6 contains information of sagittal images segmented with the DRLSE method. The maximum is shown in bold at the top of the second column. Only the groups with different values for \(u\)0 and _c_gelpad_ (GAC method) and _phi_0 and _a_gelpad_ (DRLSE method) and no significant difference (\(p>0.05\)) are reported in the subsequent lines. The values for the F-measure medians are shown along with the values for Q1, Q3 and IQR. In transverse images the maximum was 0.9589 (0.9446-0.9698, IQR 0.0252). Given this maximum value, the corresponding maximum value of the F-measure median in the segmentation of the tissue region was 0.9133 (0.8427-0.9408, IQR 0.0981). In sagittal images the maximum was 0.9524 (0.9365-0.9610, IQR 0.0245). Given this maximum value, the corresponding maximum value of the F-measure median in the segmentation of the tissue region was 0.9264 (0.8889-0.9470, IQR 0.0581). \begin{table}
\begin{tabular}{c c} \hline \hline
**Parameters Values** & **Highest Values for the F-Measure Median** \\ \hline \(u\)0 = \(W-26\), _c_gelpad \(=-0.6\)_ & **0.9589 (0.9446–0.9698, IQR 0.0252)** \\ \(u\)0 = \(W-25\), _c_gelpad \(=-0.3\)_ & 0.8713 (0.7199–0.9444, IQR 0.2245) \\ \(u\)0 = \(W-25\), _c_gelpad \(=-0.6\)_ & 0.9564 (0.9418–0.9687, IQR 0.0269) \\ \(u\)0 = \(W-25\), _c_gelpad \(=-0.6\)_ & 0.9518 (0.9303–0.9596, IQR 0.0293) \\ \(u\)0 = \(W-26\), _c_gelpad \(=-0.3\)_ & 0.8161 (0.6685–0.9357, IQR 0.2672) \\ \(u\)0 = \(W_{d}-26\), _c_gelpad \(=-0.6\)_ & 0.9675 (0.9229–0.9589, IQR 0.0360) \\ \(u\)0 = \(W-27\), _c_gelpad \(=-0.3\)_ & 0.7828 (0.6327–0.9273, IQR 0.2945) \\ \(u\)0 = \(W-27\), _c_gelpad \(=-0.6\)_ & 0.9568 (0.9388–0.9683, IQR 0.0295) \\ \(u\)0 = \(W_{d}-27\), _c_gelpad \(=-0.6\)_ & 0.9505 (0.9289–0.9597, IQR 0.0308) \\ \(u\)0 = \(W-28\), _c_gelpad \(=-0.6\)_ & 0.9560 (0.9371–0.9677, IQR 0.0306) \\ \(u\)0 = \(W_{d}-28\), _c_gelpad \(=-0.6\)_ & 0.9483 (0.9300–0.9590, IQR 0.0290) \\ \(u\)0 = \(W-29\), _c_gelpad \(=-0.6\)_ & 0.9499 (0.9014–0.9653, IQR 0.0638) \\ \(u\)0 = \(W_{d}-29\), _c_gelpad \(=-0.6\)_ & 0.9477 (0.9321–0.9604, IQR 0.0283) \\ \(u\)0 = \(W-30\), _c_gelpad \(=-0.6\)_ & 0.9532 (0.8452–0.9644, IQR 0.1192) \\ \(u\)0 = \(W_{d}-30\), _c_gelpad \(=-0.6\)_ & 0.9485 (0.9284–0.9586, IQR 0.0303) \\ \(u\)0 = \(W-31\), _c_gelpad \(=-0.6\)_ & 0.9483 (0.7432–0.9632, IQR 0.2201) \\ \(u\)0 = \(W_{d}-31\), _c_gelpad \(=-0.6\)_ & 0.9471 (0.9213–0.9591, IQR 0.0377) \\ \(u\)0 = \(W-32\), _c_gelpad \(=-0.6\)_ & 0.9383 (0.6931–0.9630, IQR 0.2699) \\ \(u\)0 = \(W_{d}-32\), _c_gelpad \(=-0.6\)_ & 0.9477 (0.9251–0.9577, IQR 0.0326) \\ \hline \hline \end{tabular}
\end{table} 
Table 4: Highest values for the F-measure median obtained in the segmentation of the gel-pad region with the GAC segmentation method in transverse images. Maximum is shown in bold. \begin{table}
\begin{tabular}{c c} \hline \hline
**Parameter Value** & **Highest Values for the F-Measure Median** \\ \hline _T_air_ = 0.04 & **0.9680 (0.9589–0.9735, IQR 0.0146)** \\ _T_air_ = 0.03 & 0.9652 (0.9563–0.9706, IQR 0.0143) \\ _T_air_ = 0.05 & 0.9668 (0.9545–0.9731, IQR 0.0187) \\ \hline \hline \end{tabular}
\end{table} 
Table 3: Highest values for the F-measure median obtained in the segmentation of the air region with the threshold segmentation method in sagittal images. Maximum is shown in bold.