###### Abstract  
The purpose of this study was to investigate the benefits of a 12-week plyometric training program intervention on lower limb joint mobility, explosive strength, advanced layup success rates, and injury rates. The study recruited 15 collegiate male basketball players as participants. They underwent basketball training five times per week, each lasting two hours, and additionally received plyometric training twice a week. The study utilized image processing software (ImageJ, version 1.54f, National Institutes of Health, Bethesda, MD, USA) to measure the lower limb joint mobility during the take-off phase of a layup and employed a force plate to assess the explosive strength of the lower limbs during the jump. Furthermore, the study examined the success rate and injury rate of advanced layups--including crossover layups, spin layups, and straight-line layups--as well as the sports injury rate. The results demonstrated that plyometric training significantly enhanced the hip, knee, and ankle joint mobility as well as lower limb explosive strength, with a strong positive correlation between these variables. Furthermore, plyometric training improved joint mobility and lower limb explosive strength. The success rate of advanced layups increased from 50% to 72%, while the sports injury rate decreased from 18% to 8%. In conclusion, plyometric training significantly improved participants' lower limb joint mobility and explosive strength, which in turn enhanced advanced layup performance and reduced the sports injury rate. Although this study provided preliminary evidence supporting the effectiveness of plyometric training, further research is needed to examine its long-term effects and other influencing factors. title: 10.11.10. Plyometric training was widely recognized as an effective method for enhancing muscular explosiveness. Its core mechanism was based on the stretch-shortening cycles (SSCs), which improved neuromuscular adaptation through rapid muscle stretching and contraction [3]. Moreover, the effects of this training on muscle injury risk [4] and the rehabilitation process had yet to reach a consensus. Existing research indicated that enhancing athletes' technical stability and joint control abilities effectively reduced the risk of injuries [5]. Therefore, combining glyometric training with injury prevention strategies could provide athletes with more comprehensive protection. The range of motion in lower limb joints was critical for movement efficiency and technical performance in basketball, especially during high-intensity actions like rapid direction changes and landing from jumps. Studies revealed that restricted joint range of motion could lead to movement compensations, thereby increasing joint load and elevating the risk of injuries [6]. Additionally, biomechanical parameters, such as ground reaction force, joint angles, and muscle activity patterns, directly reflected the effectiveness of training and the details of technical performance [7]. Improving these parameters contributed to optimizing movement techniques, reducing movement errors and injury risks. Meanwhile, sports injuries, particularly lower limb joint injuries (such as knee ligament damage), had become common issues faced by collegiate basketball players [8]. Excessive training or incorrect movement patterns could increase the risk of injuries [9]. Therefore, designing training programs that balance the enhancement of athletic performance and injury prevention became particularly important. Therefore, further exploration of the mechanisms, applicability, and potential limitations of glyometric training not only contributed to the refinement of sports science theories but also provided coaches, athletes, and rehabilitation specialists with more precise guidelines. The necessity of this research lays in addressing gaps in the existing literature, clarifying points of contention, and providing a solid scientific foundation for future applications and practices.