# A Review: Using Multiple Templates for Molecular Imprinted Polymer: Is It Good?
## 3 A Review of MT-MIPs That Have Been Created
### Template
#### 3.1.2 Organic Compounds  
Organic compounds, including phenolic compounds, are often used as templates [9]. Phenolic compounds, particularly chlorinated compounds, are harmful and persistent in the environment at low concentrations and have been added to the priority pollutant list [9; 122]. Hence, researchers have synthesised MT-MIPs to recognise these compounds, including polycyclic aromatic hydrocarbons (PAHs) as templates. PAHs are a type of persistent organic pollutant that is typically detected in low concentrations in the environment. Household human and chemical waste, automobile exhaust products, storm water run-off from both impervious and pervious areas such as roads, parking lots, and construction sites, industrial effluents from chemical manufacturing, and carbonaceous waste incineration are all sources of PAHs in urban areas. They subsequently make their way into wastewater treatment plants through the sewage system [61; 123; 124; 125; 126]. PAHs have also been added to priority pollution lists due to environmental and possibly carcinogenic health concerns [127; 126]. [PERSON] et al. [102] used nitrogen compounds (aniline, indole, and 3-methylindole) in oil as templates; these compounds are pollutants and harmful to the environment. Other research has also used organic compounds that are harmful to the environment as templates, including dibutyl phthalate (DBP), diethyl phthalate, and dimethyl phthalate, which are phthalate esters (PAEs), synthetic organic compounds intensively used as important additives in plastic industry. PAEs can escape from plastic materials into the environment because they are not chemically linked to the polymeric matrix [101]. In one study, the authors used methyl parathion and quianphos, organophosphorus pesticides (OPPs) that are irreversible acetylcholine esterase (AChE) inhibitors, as templates. OPPs are frequently used to control pests in agriculture. However, OPP residues are a human health risk because prolonged exposure to OPPs might damage several organs [128]. For the enrichment of tracing this toxic organic compound, many traditional and novel pretreatment strategies have been reported, including SPE. It is a simple and easy-to-automate approach that has been widely used in environmental sectors. Target analytes are frequently retained on their functionalised surface by physicochemical interaction for the most commonly used SPE sorbents. Other matrix molecules may unintentionally be retained on SPE sorbents in addition to the target. Thus, MIPs with artificial recognition cavities complementary to the template molecules in shape, size, and chemical functionality can specifically rebind the template molecules from the complicated matrices that are being utilised for SPE [9; 129; 27]. In addition to analysing components that are harmful to the environment and health, MIPs with organic compounds as a template are used to separate compounds from herbal plants. Researchers have used phenyl pyruvate acid and DL-tyrosine as templates. These compounds contain an amino (-NH2) group, a carboxylic acid (-COOH) group, and a keto acid (-COCOOH) group, which is present in dencichine. This compound is the primary component of _Panax notoginseng_ and other traditional Chinese medications; it increases platelets and promotes haemostasis [130; 131]. Numerous analytical techniques have been developed for its identification due to the positive and negative pharmacological