## 5 Conclusions  
The interest in resveratrol commercial supplements has increased due to its proven health benefits (e.g., anti-aging, anti-inflammatory, anti-carcinogenic, neuroprotective, and antioxidant agents), and that it could protect against, to a certain extent, heart and metabolic disorders.  
The majority of resveratrol supplements available on the market are made of extracts obtained from the roots of Japanese knotweed (_Polygonum cuspidatum_); some studies showed that emodin, a compound that could have a laxative effect, was found in partially purified extracts of resveratrol. Research studies show that resveratrol could be extracted from vine waste, which is abundant in this compound, without contamination of emodin.  
Moreover, vine waste resulting from annual trimming is utilized as fertilizer by grinding or burning. Agricultural vine waste is an important source for phytochemicals, although economically it is unevaluated.  
During the vineyard trimming process, a considerable amount of green mass (portions of shoots, leaves, tendrils) is removed. Vine shoots contain up to 10 times more trans-resveratrol than tendrils, and up to 40 times more than leaves. Although, besides vine shoots, the vineyard waste also contains trans-resveratrol, extraction and purification are not economically recommended.  
To increase the extraction yield in the pruned vine shoots, these should be kept for 9-10 weeks at a controlled temperature, at around 20 \({}^{\circ}\)C. The increase is 18.063% on day 70 of storage compared to the first day of harvest.  
Mechanical stress did not influence the increase of resveratrol content in vine shoots. A small difference was recorded between the sample that was cut in pieces smaller than 0.5 cm (1641.64 mg/kg D.W.) and the uncut samples (1667.49 mg/kg D.W.).  
A correlation among the resveratrol content, TPC, and DPPH % inhibition could not be established, due to the fact that polyphenols and other compounds with antioxidant activity present in vine shoots, other than trans-resveratrol, can increase, decrease, or remain constant during the 90 days. The only similarity was that resveratrol content and DPPH % inhibition increased, with the difference being that the resveratrol content significantly increased until day 70, and then dropped from day 76; DPPH % inhibition slightly increased until day 85, and then decreased 50% over the next 5 days.  
**Author Contributions:** Conceptualization, A.L.C. and G.G.; methodology, A.L.C.; validation, A.L.C. and G.G.; formal analysis, A.L.C.; investigation, A.L.C.; resources, A.L.C. and G.G.; data curation, A.L.C.; writing--original draft preparation, A.L.C.; writing--review and editing, A.L.C.; visualization, G.G.; supervision, G.G.; project administration, G.G.; funding acquisition, G.G. All authors have read and agreed to the published version of the manuscript.  
**Funding:** This research received no external funding.  
**Institutional Review Board Statement:** Not applicable.  
**Informed Consent Statement:** Not applicable.  
**Data Availability Statement:** All data related to this study are explicitly plotted in the figures in this article.  
**Conflicts of Interest:** The authors declare no conflict of interest.