## 3 Results and Discussion  
### OEO Yield and Chemical Composition  
A greenish-yellow oil with a pungent smell was obtained from dry \(O\). _vulgare_ var. _aureum_ L. (stems, leaves, and flowers), with a 0.34% (\(v/w\)) yield. Our results agree with \begin{table}
\begin{tabular}{c c c} \hline
**Protein** & **PDB ID** & **Native Ligand** & **Grid Box Center** \\ \hline
**CYP2C9** & 1 OG5 & & center\_x = \(-\)20.4200 \\  & & center\_y = 85.2723 \\  & & center\_z = 38.2181 \\  & & size\_x = 9.6524 \\  & & size\_y = 10.6625 \\  & & size\_z = 11.5535 \\  & & & center\_x = 18.4683 \\  & & center\_y = \(-\)5.1659 \\  & & center\_z = \(-\)0.0901 \\  & & size\_x = 12.3286 \\  & & size\_y = 15.3831 \\  & & size\_z = 15.1287 \\  & & & center\_x = 37.6450 \\  & & center\_y = 19.2898 \\  & & center\_z = 17.5578 \\  & & size\_x = 11.6388 \\  & & size\_y = 9.8519 \\  & & size\_z = 10.1251 \\  & & \\ \end{tabular}
\end{table} 
Table 1: _Cont._those mentioned in the literature, which record yields of obtaining EOs from different oregano species as lower than 1% [32]. Table 2 summarizes the chemical compositions of the EO isolated from \(O\). _vulgare_ var. _aureum_ L. by steam distillation. The GC-MS analysis identified 38 compounds in the analyzed sample (Figure 1), with gamma-terpinene (22.96%), para-cymene (14.72%), germacrene (11.64%), beta-trans-ocimeen (9.81%), and cis-beta-ocimeen (7.65%) as main compounds of the oil (Table 2). In addition, beta-linalool (3.61%), isothymol methyl ether (3.34%), beta-phellandrene (2.44%), beta-caryophyllene (2.35%), alpha-terpinene (1.84%), beta-cadinene (1.78%), alpha-farnesene (1.55%), (-)-spathulenol (1.35%), beta-myrcene (1.31%) and alpha-himalachene (1.29%) were identified in smaller quantities. \begin{table}
\begin{tabular}{c c c c c} \hline
**No.** & **Compound Name** & **MW (g/mol)** & **RIexp.** & **Area \%** \\ \hline
**1** & Alpha-thujene & 136.23 & 912 & 0.83 \\ \hline
**2** & Alpha-pinene & 136.23 & 919 & 0.35 \\ \hline
**3** & Camphene & 136.23 & 934 & 0.16 \\ \hline
**4** & Beta-phellandrene & 136.23 & 955 & 2.44 \\ \hline
**5** & Beta-pinene & 136.23 & 960 & 0.26 \\ \hline
**6** & Beta-myrcene & 136.23 & 970 & 1.31 \\ \hline
**7** & Alpha-phellandrene & 136.23 & 987 & 0.15 \\ \hline
**8** & 3-Carene & 136.23 & 990 & 0.05 \\ \hline
**9** & Alpha-terpinene & 136.23 & 998 & 1.84 \\ \hline
**10** & Para-cymene & 134.21 & 1007 & 14.72 \\ \hline
**11** & Beta-terpinyl acetate & 196.29 & 1011 & 0.35 \\ \hline
**12** & Beta-trans-ocimene & 136.23 & 1018 & 9.81 \\ \hline
**13** & Cis-beta-ocimene & 136.23 & 1030 & 7.65 \\ \hline
**14** & Gamma-terpinene & 136.23 & 1044 & 22.96 \\ \hline
**15** & Beta-linalool & 154.25 & 1087 & 3.61 \\ \hline
**16** & Isothymol methyl ether & 164.24 & 1243 & 3.34 \\ \hline
**17** & Dihydroedulan & 194.31 & 1299 & 1.01 \\ \hline
**18** & Carvacrol & 150.22 & 1309 & 0.62 \\ \hline
**19** & Alpha-cubebene & 204.35 & 1363 & 0.06 \\ \hline
**20** & Alpha-copaene & 204.35 & 1394 & 0.27 \\ \hline
**21** & Beta-bourbonene & 204.35 & 1402 & 0.97 \\ \hline
**22** & Beta-elemene & 204.35 & 1408 & 0.71 \\ \hline
**23** & Beta-caryophyllene & 204.35 & 1439 & 2.35 \\ \hline
**24** & Beta-cubebene & 204.35 & 1450 & 0.45 \\ \hline
**25** & Alpha-caryophyllene & 204.35 & 1476 & 0.46 \\ \hline
**26** & Alloarmodandendrene & 204.35 & 1481 & 0.75 \\ \hline
**27** & Germacrene D & 204.35 & 1503 & 11.64 \\ \hline
**28** & Gamma-elemene & 204.35 & 1517 & 0.98 \\ \hline
**29** & Alpha-muurolene & 204.35 & 1520 & 0.52 \\ \hline
**30** & Alpha-farnesene & 204.35 & 1525 & 1.55 \\ \hline \end{tabular}
\end{table} 
Table 2: Chemical composition of OEO as determined by GC-MS analysis. [PERSON] et al. [33] reported linalool (26.54%), para-cymene (20.81%), and gamma-terpinene (13.73%) as the major compounds for the oil isolated from Romanian _O. aureus_. Furthermore, high contents of linalool (25.5%), para-cymene (20.7%), and gamma-terpinene (15.66%) were also documented for the golden oregano oil by [PERSON] et al. [34]. In contrast, the oil obtained from Polish _O.