## 2 Precision Medicine and Cardiology
\begin{table}
\begin{tabular}{p{56.9 pt} p{56.9 pt} p{56.9 pt} p{56.9 pt} p{56.9 pt}} \hline
**S.N.** & **Authors** & **Year** & **Results** & **Clinical Significance** & **References** \\ \hline
1 & [PERSON] et al. & 2022 & The research focuses on how AI may bridge the gap between data-rich technologies and their deployment. It will be possible to use human pluripotent stem cells (hPSCs) in cardiovascular clinical care by developing isogenic hPSC cell lines as a control for hPSCs with disease-specific mutations and a large number of hPSC lines with gene mutations, for the in vitro modeling of human diseases with complex genotypes and phenotypes. & [12] \\ \hline
2 & [PERSON] et al. & 2021 & Novel biomarkers can distinguish between left and right ventricular hypertrophy/failure. & Novel biomarkers can distinguish left ventricular hypertrophy/failure, assess right ventricular disease severity, and potentially identify maladaptive changes in RV size, function, and architecture. & [13] \\ \hline
4 & [PERSON] et al. & 2021 & In both healthy and pathological cardiovascular tissues, scRNA-seq has enabled the characterization of heterogeneous cell subpopulations with distinct genetic profiles. & Novel biomarkers can distinguish left ventricular hypertrophy/failure, assess right ventricular disease severity, and potentially identify maladaptive changes in RV size, function, and architecture. & [14] \\ \hline
5 & [PERSON] et al. & 2021 & In both healthy and pathological cardiovascular tissues, scRNA-seq has enabled the characterization of heterogeneous cell subpopulations with distinct genetic profiles. & In pro-inflammatory macrophages of the human carotid plaque, elevated HDAC9 was related to matrix metalloproteinase 1 (MMPI) and MMP2 production, while decreased HDAC9 was seen to promote resolution of inflammation and reverse cholesterol transfer, which may halt or reverse the disease process. & [15] \\ \hline
6 & [PERSON] et al. & 2020 & Emerging biomarkers—cardiac myosin binding protein C, SNPs, and non-coding RNAs. & In pro-inflammatory macrophages of the human carotid plaque, elevated HDAC9 was related to matrix metalloproteinase 1 (MMPI) and MMP2 production, while decreased HDAC9 was seen to promote resolution of inflammation and reverse cholesterol transfer, which may halt or reverse the disease process. & In pro-inflammatory macrophages of the human carotid plaque, elevated HDAC9 was related to matrix metalloproteinase 1 (MMPI) and MMP2 production, while decreased HDAC9 was seen to promote resolution of inflammation and reverse cholesterol transfer, which may halt or reverse the disease process. & [16] \\ \hline
7 & [PERSON] et al. & 2020 & In cardiovascular medicine, AI has shown promise as a tool to improve patient care and increase the efficiency of cardiologists. & The integration of AI and laboratory medicine can enable personalized care in cardiovascular medicine. & [18] \\ \hline
8 & [PERSON] et al. & & New technologies in heart failure, atrial fibrillation, and cardiac rehabilitation offer a low-cost, non-invasive solution to long-term monitoring and management. & The availability of current devices with massive datasets offers a valuable tool for predicting the progression and outcome of various cardiovascular illnesses. Due to continuous monitoring, this new guided therapy can provide rapid and tailored treatment while also having a substantial psychological impact on patients. & [19] \\ \hline
9 & [PERSON] et al. & 2020 & Building personalized maps of cardiovascular risk and designing individualized diagnostic and treatment approaches can be made possible by the integration of epigenetic and genetic data. & [20] \\ \hline \end{tabular}
\end{table} 
Table 1: A compilation of important reviews underlining the role of precision medicine in cardiology.