## 4 Use Case
### Systematic Approach for SCVAD Modeling
#### 4.3.2 Modeling of Intervention Protocols  
Based on the previously presented diagnostic models, mitigation modules for adverse processes are specified, configuring intervention protocols defined by the medical team for the composition of the digital model for adverse process mitigation (DMAPM) shown in Figure 22. To address the patient's needs regarding critical adverse process AE1, the 'adverse process mitigation module (AE1)' was specified, as detailed in the PFS in Figure 23. The medical team specifies mitigation activities which will be detailed below. The activity 'pre-pump thrombosis mitigation AE1.1' is detailed in the PFS in Figure 24. When activated, the first mitigation activity that may be performed is 'thrombectomy', followed by patient supervision by the medical team based on monitoring the execution of required mitigation activities. Based on the recommended actions from the risk identification phase, activities that may be executed for the degeneration of adverse process AE1 include'medical discharge' or 'pump exchange surgery'. Figure 25 illustrates the corresponding PN for the activity 'pre-pump thrombosis mitigation AE1.1', including control elements and resources for data flow sharing and representation with the external environment. Figure 23: PFS and detailing of the thrombosis mitigation module for the device (AE1). Figure 22: PFS and detailing of the digital model for adverse process mitigation (DMAPM). As illustrated in Figure 23, the activities 'pre-pump thrombosis mitigation AE1.1', 'intra-pump thrombosis mitigation AE1.2', and 'post-pump thrombosis mitigation AE1.3' are linked to the adverse process (AE1), which is subdivided into these adverse activities. As shown in Figure 24, after executing the mitigation activity 'thrombectomy', two secondary mitigation activities may be enabled, namely,'medical discharge', if the thrombosis is successfully removed, or 'pump exchange surgery', if thrombosis persists. Figure 25 illustrates the introduction of control elements and resources for sharing and representing data flow with the external environment. The activity 'intra-pump thrombosis mitigation AE1.2' is detailed in PFS in Figure 26. When enabled, the first mitigation activity that may be performed is 'thrombysis', which degrades the adhered thrombus through clinical intervention. As mentioned, real-time information is provided for the medical team to monitor the execution of required mitigation activities. Based on the recommended actions from the risk identification phase, the activities that may be performed for the degeneration of adverse process AE1 include'medical discharge' or 'pump exchange surgery'. Figure 27 illustrates the corresponding PN for the activity 'intra-pump thrombosis mitigation AE1.2', which includes control elements and resources for data flow sharing and representation with the external environment. Figure 24: PFS and detailing of the activity ‘pre-pump thrombosis mitigation AE1.1’. Figure 25: PN corresponding to the activity ‘pre-pump thrombosis mitigation AE1.1’. As shown in Figure 26, after executing the mitigation activity 'thrombysis', two secondary mitigation activities may be enabled, namely,'medical discharge' if the thrombus is successfully degraded or 'pump exchange surgery' if the thrombus persists. Figure 27 illustrates the introduction of the control elements and resources for sharing and representing data flow with the external environment. Similarly to the previous activities, the 'post-pump thrombosis mitigation AE1.3' activity is detailed in PFS in Figure 28. When enabled, the first mitigation activity that may be performed is'stent implant surgery' to restore adequate blood flow to the patient. As mentioned earlier, real-time information is provided to allow the medical team to monitor the execution of the required mitigation activities.