# Editorial on Special Issue \"Biomaterials, Polymers and Tissue Engineering\"
###### Abstract  
The development of new materials, new manufacturing methods, and new techniques has attracted interest from many researchers in recent decades. Polymers used in biomedical applications should be nontoxic, biodegradable in most cases, biocompatible, easy to process and sterilize, and meet regulatory requirements specific to their given application. As compared with metals or ceramics, polymers can be easily processed into various shapes and their overall properties can be tailored by changing the molecular architecture (e.g., crosslinking, branching, and increasing the molecular weight of the polymer chains) and adding different additives. In recent years, significant advances have been made to develop new polymer-based biomaterials in the form of biodegradable and biocompatible scaffolds, diagnostic systems, and pharmaceutical formulations [1]. These polymers can be either of natural or synthetic origin and have been engineered to interact with biological systems to regenerate, repair, and restore the function of damaged tissues or organs. Polymeric biomaterials have gained intensive interest in both research and clinical settings and have contributed to the development of personalized biomedical devices and customized implants. In light of the above, the present Special Issue was introduced to collect articles that addresses the very important topic of biomaterials, with a special focus on application of polymers in the biomedical engineering field. This collection comprises four research articles, one communication, and five review articles. In the present editorial, the most interesting findings of each research paper are presented, along with a brief description of each review article. 202210390902222103909000000000000000000000000000000000000000000  
designed as wound dressings, is also presented in this review. Besides cellulose-based biomaterials, lipid nanoparticles are shown also to be successful in promoting the wound-healing process, being very effective in application to burn wounds and chronic wounds [3]. In their review, [PERSON] et al. focus on nanosized, lipid-based drug-delivery systems, describing their numerous applications in managing skin wounds. Lipid nanoparticles can maintain skin hydration due to an occlusive biofilm formed at the surface of the stratum corneum. Interesting research approaches refer to the incorporation of nucleic acid into lipid nanoparticles developed for chronic ischemic wounds or the encapsulation of capsaicin and anti-TNF \(\alpha\) to treat skin inflammation, or delivery of fusidic acid using lipid nanoparticles, to treat burn infections. The authors concluded that nanosized, lipid-based drug-delivery systems can enhance the efficacy of wound-healing therapies [3]. The paper by [PERSON] and [PERSON] also focuses on wound dressings, specifically the biomaterials using curcumin, vitamins, and essential oils [4]. The article describes the synthesis and modifications of biomaterials with bioactive compounds (including curcumin and essential oils) and summarizes the biological effects of the novel wound dressings on the enhancement of skin regeneration. Tissue engineering is an interdisciplinary field that seeks to repair, replace, or regenerate tissues or organs. Biomaterials for tissue engineering should have controlled surface chemistry and porosity, tunable biodegradability, and must be able to promote cell adhesion, migration, and differentiation. An overview on the biomaterials used to design scaffolds for retinal tissue engineering is presented in the paper by [PERSON] et al. [5]. These biomaterials include natural polymers, synthetic polymers, hybrid polymers, decellularized tissues, and thermoresponsive hydrogel polymers. The authors discuss the advances in the fabrication of scaffolds for retinal repair using stem-cell-derived grafts, detailing the transplantation studies in animal models and their application in current clinical trials. In this Special Issue, in vivo experiments were reported by [PERSON] et al. using adult rats as an animal model [6].