## 4 Discussion
\begin{table}
\begin{tabular}{l l l||r r r r} \hline \hline
**Gene ID** & **Function** & **Chromosome** & \begin{tabular}{c} **Log2 Ratio** \\ **MK-1/MK-2** \\ \end{tabular} & \begin{tabular}{c} **Log2 Ratio** \\ **DK/FB-A** \\ \end{tabular} & \begin{tabular}{c} **Log2 Ratio** \\ **DK/FB-B** \\ \end{tabular} & \begin{tabular}{c} **Log2 Ratio** \\ **DK/FB-C** \\ \end{tabular} \\ \hline _Her003788_ & \begin{tabular}{c} Linoleate 10R-lipoxygenase5 ygenase \\ \end{tabular} & Chr04 & \(-0.66\) & \(0.57\) & \(-0.26\) & \(-0.10\) \\ _Her003832_ & \
\begin{tabular}{c} Linoleate 10R-lipoxygenase5 ygenase \\ \end{tabular} & Chr04 & \(-1.55\) & \(-1.88\) & \(-0.07\) & \(-1.00\) \\ _Her005338_ &
\begin{tabular}{c} Linoleate 10R-lipoxygenase5 ygenase \\ \end{tabular} & Chr05 & \(-0.91\) & \(-0.04\) & \(-1.54\) & \(-0.99\) \\ _Her02337_ & Alpha-muroulene synthase & Chr02 & \(-0.79\) & \(-0.42\) & \(-0.45\) & \(0.45\) \\ _Her005433_ & Alpha-muroulene synthase & Chr05 & \(-0.47\) & \(-0.14\) & \(-1.37\) & \(-1.24\) \\ _Her006723_ & Trichadiene synthase & Chr06 & \(-2.60\) & \(0.44\) & \(0.24\) & \(-0.07\) \\ _Her006724_ & Trichadiene synthase & Chr06 & \(0.87\) & \(-1.69\) & \(-3.21\) & \(-3.83\) \\ _Her010605_ & Trichadiene synthase & Chr12 & \(1.51\) & \(-1.38\) & \(-2.54\) & \(-2.08\) \\ _Her010608_ & Trichadiene synthase & Chr12 & \(-2.63\) & \(-0.88\) & \(-1.8\) & \(-1.38\) \\ \hline \hline \end{tabular}  
* MK-1 and MK-2: mononuclear mycelium; DK: dikaryotic mycelium; FB-A: primitive stage; FB-B: fruiting body stalk; FB-C: fruiting body spines. Orange indicates a significantly up-regulated gene; green indicates a significantly down-regulated gene; gray indicates no significant difference in expression.  
\end{table} 
Table 7: Genes and enzymes of sesquiterpene biosynthesis pathway. **Supplementary Materials:** The following supporting information can be downloaded at: [[https://www.mdpi.com/article/10.3390/jof10100704/s1](https://www.mdpi.com/article/10.3390/jof10100704/s1)]([https://www.mdpi.com/article/10.3390/jof10100704/s1](https://www.mdpi.com/article/10.3390/jof10100704/s1)): Figure S1: Calibration plot of scutellarity; Figure S2: Protoplast mononuclearization results of DK. **(A)** Morphology of protoplas DK under 40\(\times\) microscope, the protoplasts are circled in red. **(B)** Electrophrogram of ITS-PCR. Figure S3: KEGG enrichment analysis of DEGs under different groups. **(A,B)** Up-regulated DEGs and down-regulated DEGs in MK-1 and MK-2 comparison groups. **(C,D)** Up-regulated DEGs and down-regulated DEGs in DK and FB-A comparison groups. **(E,F)** Up-regulated DEGs and down-regulated DEGs in DK and FB-B comparison groups. **(G,H)** Up-regulated DEGs and down-regulated DEGs in DK and FB-C comparison groups; Figure S4: KEGG pathway annotation of DEGs in different groups. **(A,B)** Up-regulated DEGs **(left)** and down-regulated DEGs **(right)** in MK-1 and MK-2 comparison groups. **(C,D)** Up-regulated DEGs **(left)** and down-regulated DEGs **(right)** in DK and FB-A comparison groups. **(E,F)** Up-regulated DEGs **(left)** and down-regulated DEGs **(right)** in DK and FB-B comparison groups. **(G,H)** Up-regulated DEGs **(left)** and down-regulated DEGs **(right)** in DK and FB-C comparison groups. Table S1: Count of HiFi reads and de novo assembly contigs; Table S2: _H. coralloides_ genome assessed by BUSCO pipeline; Table S3: Statistics of telomeres of the both ends of chromosomes in _H. coralloides_; Table S4: Classification of repetitive sequences in _H. coralloides_; Table S5: Statistics of tRNA in _H. coralloides_; Table S6: Metabolic pathways and gene distribution related to the synthesis of terpenoids in each group; Table S7: Identification of the putative gene clusters for terpen in _H. coralloide_ genome; Data S1: The amino acid coding sequence of genes. **Author Contributions:** Q.H., J.F. and B.X. ; methodology, T.Z., Y.Z., B.H. and P.Z. ; software, K.M. and J.L. ; resources, Y.L. and K.M. ; data curation, K.M. ; writing--original draft preparation, K.M. ; writing--review and editing, B.X. and K.M.