TAM2 [5; 6], unified theory of acceptance and use of technology, UTAUT [7]). These extensions added independent variables, as well as mediators and moderators, to increase the model's explanatory power. For example, a meta-analysis [8] revealed that a user's perception that most people who are important to him (her) think he (she) should, or should not, use the technology (referred to as \"subjective norm\") influences perceived usefulness, behavioral intention, and actual system use. Because human perception and behavior in general, hence also users' technology perceptions and acceptance behavior, are influenced by personality, it is not surprising that researchers have also investigated the role of personality in technology acceptance (hereafter: TA). Personality is defined as people's \"stable individual differences in cognitive, emotional and motivational aspects of mental states that result in stable behavioral action (especially emotional) tendencies [...]\" [9] (p. 1). In fact, it has been found that personality affects technology perceptions and TA decisions [10; 11; 12; 13]. Moreover, it is an established fact that significant gender differences exist in personality (see meta-analyses by [PERSON], [PERSON], and [PERSON] [14] and [PERSON] [15] as well as studies by [PERSON] and [PERSON] [16] and [PERSON], [PERSON], and [PERSON] [17]). In addition, evidence indicates that computer usage decisions of women are more strongly influenced by perceived ease of use, whereas men's decisions are more strongly influenced by perceived usefulness [18]. Thus, gender affects TA decisions. This effect possibly has its root cause in gender differences that are related to personality. Specifically, women typically have less self-efficacy with regards to computers (computer self-efficacy) and higher levels of computer anxiety than men [7; 18] making factors related to ease of use (e.g., interface usability) more salient to them. In contrast, men usually have more achievement needs and are more task-oriented than women, making factors related to usefulness (e.g., functions of a software tool) more salient to them (please also see consideration of user gender in early works of [PERSON] [7; 18]). However, the role of user gender in the personality-TA relationship, to the best of our knowledge, has not been empirically studied so far; except for one study which, however, only touches on the topic (see our discussion of [PERSON] et al. [11] in the next section). A contribution to filling this research gap is not only important from an academic perspective. Rather, shedding light on the role of user gender in TA perceptions under consideration of personality is also critical for systems engineering in practice. Evidence [19; 20; 21] indicates that consideration of user gender in systems development (e.g., user interface design) may have beneficial effects on important outcome variables in human-technology interaction that are related to TA decisions, such as user satisfaction, trust, or sales in online shopping contexts. Thus, an answer to the question whether gender moderates the relationship between user personality and TA decisions is important. If a moderation effect exists, consideration of the interaction between users' personality and gender is critical in systems engineering and design. If a moderation effect does not exist, consideration of personality and gender in engineering and design does not become less important. However, what a missing moderation effect would indicate is that their joint consideration (i.e., personality and gender) is less complex because their influence on TA would be independent from each other. Against the background of this research gap, we conducted a survey study with a large sample (\(N=686\)) to investigate possible gender differences in the personality-TA relationship. The remainder of this paper is structured as follows. First, we discuss related work. This discussion is organized along the conceptual framework as shown in Figure 1. Afterwards, we describe the methods of our study.