## 2 Traditional Uses  
_Elaodendron buchananii_ (Loes.) Loes. is an evergreen shrub or tree with a branching, rounded crown found in eastern Africa, particularly Uganda and Kenya [12]. Despite its toxic nature, _E. buchananii_ is occasionally utilized in conventional practice of medicine. Leaf extracts are used to treat fever, as an abortifacient, oxytocin, tonic, and vermifuge [13, 14, 15]. Chewing the leaves is considered beneficial for the treatment of diarrhea. Gastrointestinal problems, bloody coughing, excessive uterine bleeding, and infertility are treated using root decoctions. Syphilis is treated using root powder [13,16,17]. On wounds, the root powder is administered topically. The bark decoction is also used to cure leukemia [12]. _Elaodendron crocum_ (Thunb.) DC., also known as saffron, saffron wood, and forest saffron, is an evergreen tree with a tidy, vertical frame found in various parts of South Africa (Ladismith, KwaZulu-Natal, Limpopo, Southern Cape forests) and in Zimbabwe (Mount Cherinda) [7]. The bark of this plant is used as a febrifuge and emetic in therapeutic approaches to treat opportunistic infections caused by the human immunodeficiency virus (HIV) [7,18]. Tuberculosis and other associated disorders, such as blood in sputum, chest congestion, cough, and sore throat have historically been treated and managed using the bark [18]. The roots, bark, and leaves of the plant are used as herbal treatments to clear the gastrointestinal system and control fever [19]. Preparations of _Elaodendron glacum_ (Rottb.) Pers. have been employed by conventional healers as a remedy for a number of diseases such as diabetes. As scruntatories, the dried and powdered leaves are employed [20]. The dried leaves are also burned, and the resulting smoke is utilized as a disinfect to treat some nerve illnesses, especially to rouse women from hysterics [21]. Headache is relieved by snuffing the powdered leaves. Fresh root bark is ground into a paste with water and applied to swellings as a poultice. The root is reported to have anti-snake-venom properties. As an emetic, cold-water infusion of the pulverized roots is employed [4; 22]. _Elaeedendron orientale_ Jacq., sometimes known as the fake olive, is an indigenous plant of the Mascarene Islands and Madagascar [9]. The bark has traditionally been used to cure chest infections, venereal illness, and scorpion fish poisoning. The leaves are emetic and asringent. The combination of leaves with those of _Kalancheo pinnata_ (Crassulaceae) generate bufadienolides, used to alleviate hypertension and treat seafood allergies [9]. _Elaeedendron roxburghii_ Wight and Arn. Is found in India, Japan, China, Thailand, and Nepal and its roots are used to treat snake bite [23]. _Elaeedendron schweinfurthianum_ ([PERSON].) [PERSON] is a species of evergreen deciduous trees and shrub. The herb exhibits antibacterial, anti-HIV, and anti-plasmodial properties, among many others [4]. In Tanzania, traditional medicinal claims have been made for treating a variety of non-infectious disorders using _Elaeedendron schlechteranum_ ([PERSON].) [PERSON]. An oral decoction of the root is used to treat male dysfunction, female fertility problems, menstrual irregularities, inflammatory diseases, anemia, and heart issues such as high blood pressure and basic body discomfort. On foul-smelling septic wounds, root and stem bark powder is used [24]. Carbuncles and boils are treated using a slurry made from the leaves. Root bark extracts were shown to have a powerful antimicrobial effect. Anti-HIV activity was also reported against HIV-2 (ROD strain) and HIV-1 (IIIB strain) [24]. _Elaeedendron transvalense_ ([PERSON]) [PERSON] is a medium and small deciduous tree frequently known as a bushveld safron or anthill safron. In Zambia, Zimbabwe, Mozambique, Swaziland, Botswana, Namibia, Angola, and South Africa, the genus is found as evergreen woods, near rivers, stony highlands, and insect piles [25]. In southern Africa, the root macerate and bark of _E.