# Recent Advances in Optical Detection of Aminoglycosodies
## Abbreviations  
ABTS 2,2'-Azinobis-(3-ethylbenzthiaazoline-6-sulphonate)  
AGs  Aminoglycososides  
Ag NCs  Silver nanoclusters  
ALP  Alkalaine phosphatase  
Ag NPs  Silver nanoparticles  
APTES  Aminopropyltriethoxysilane  
Au NCs  Gold nanoclusters  
Au NPs  Gold nanoparticles  
BSA  Bovine serum albumin  
CDs  Carbon dots  
CE  Capillary electrophoresis  
CL  Chemiluminescence  
CNTs  Carbon nanotubes  
dsDNA  Double-strand DNA  
dNTP  Deoxy-ribonucleoside triphosphate  
ECL  Electogenerated chemiluminescence  
ECCG  Epigallocatechin gallate  
ELISA  Enzyme-linked immunosorbent assay  
ELSD  Evaporative light-scattering detection  
Exo III  Exonuclease III  
FAM  Carboxyfluorescein  
FL  Fluorescence  
FRET  Fluorescence resonance energy transfer  
GC  Gas chromatography  
GFP  Fluorescent protein  
GO  Graphene oxide  
GQDs  Graphene oxide quantum dots  
HCA  Hierarchical clustering analysis  
HCR  Hybridization chain reaction  
HPLC  High-performance liquid chromatography  
HRP  Horseradish peroxidase  
LOD  Limit of detection  
LFA  Lateral flow assay  
MIPs  Molecular imprinting polymers  
MOFs  Metal-organic frameworks  
MRL  Maximum residue limit  
MS  Mass spectrometry  
OPD \(o\)-phenylenediamine  
PAD  Pulsed amperometric detectors  
PATP 4-aminothiophen  
PCA  Principal component analysis  
PCR  Polymerase chain reaction  
PDDA  Poly(diallyl dimethyl ammonium chloride)  
POCT  Point of care test  
QDs  Quantum dots  
RCA  Rolling circle amplification  
RRS  Resonance Rayleigh scattering  
RRS-ET  Resonance Rayleigh scattering-energy transfer  
SDS  Sodium dodecyl sulfate  
SELEX  Systemic evolution of ligands by exponential enrichment  
SERS  Surface-enhanced Raman spectroscopy  
SPR  Surface plasmon resonance  
SSB  Single-stranded DNA-binding protein  
ssDNA  Single-strand DNA  
TAMRA  Carboxytetramethylrhodamine  
TCP  Tetrakis(4-carboxyphenyl)porphyrin  
TEOS  Tetraethoxysilane  
TMB  Tetramethyl benzidine  
\begin{table}
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\begin{table}
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**Target** & **Recognition** & **Detection Mechanism** & **Linear Range** & **LOD** & **Time** & \multicolumn{2}{c}{**Seletivity \(\mathbf{\mathbf{\mathbf{\mathbf{\mathbf{\mathbf{\mathbf{\mathbf{\mathbf{\mathbf{\mathbf{\mathbf{\mathbf{\mathbf{\mathbf{\mathbf{\mathbf{\mathbf{\mathbf{\mathbf{\bm}}}}}}}} }}}}}}  
\begin{table}
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**Target** & **Principle/Mode** & **Amplification Method** & **Linear Range** & **LOD** & **Time** & \multicolumn{2}{c}{**Selectivity ***} & \multicolumn{1}{c}{**Sample**} \\  & **(nM)** & **(nM)** & **(nM)** & **(min)** & **A** & **B** & **C** & **(Recovery, \%)** & **Ref** \\ \hline \multirow{8}{*}{Kanamycin} & HRF-catalysed TMB reaction & Au NPs as amplification carrier & \(1.7\times 10^{-4}\)-\(1.7\times 10^{5}\) & \(1.7\times 10^{-4}\) & 150 & - & \(\circ\) & \(\circ\) & \(\circ\) & Milk (100–104) & [84] \\  & Microfluidic chip chip & RCA & 1.36–17,000 & 0.51 & 160 & \(\circ\) & \(\circ\) & \(\circ\) & & Milk and fish & [88] \\  & with label-free FL & Target-assisted recycling and & & & & & & & & (90–106) & [88] \\  & Turn-on FL & HCR & & & & & & & & Milk (\(\cdot\)) & [86] \\  & DNAzyme-catalyzed & & & & & & & & & & \\  & colorimetric reaction & & & & & & & & & \\  & Spilt C- & & & & & & & & & \\  & Quadrupple DNAzyme & Dual nicking enzyme signal & & & & & & & & \\  & catalyzed AIST5 colorimetric & & amplification & & & & & & & \\  & reaction & & & & & & & & & Milk, fish, and & [21] \\  & Label-free FL & Target recycling and HCR & & & & & & & & Milk, honey, & \\  & & & & & & & & & & \\ \hline \multirow{4}{*}{Streptopomycin} & Colorimetric immunoassay based on [Fe(T)-Phen] system & Liposome & 1.7–34,000 & 0.68 & 130 & \(\circ\) & \(\circ\) & - & muscle and & [85] \\  & & & & & & & & & kidney (86–114) & \\ \hline \hline \end{tabular}  
* no data.  
\end{table}
Table 4: Assay performance of the optical detection methods for AGs with amplification strategies *.