## 4 Salt-Tolerant Plants as Sources of Neuroprotective and Mental Health Commodities
### In Vitro Assays
\\ \hline \multirow{4}{*}{_Nitraia retusa_ ([PERSON]) [PERSON]} & \multirow{4}{*}{[PERSON]} & \multirow{4}{*}{Mexoration with 10\% ethanol for 2 weeks} & \multirow{4}{*}{[PERSON]} & \multirow{4}{*}{Amyloid \(\beta\)-induced cytotoxicity and amyloid \(\beta\)} & \multirow{4}{*}{Amyloid \(\beta\)-induced cytotoxicity (increased cell} \\  & & & & & (C\({}_{50}=94\) ug/mL); Acheme \\  & & & & & (C\({}_{50}=951\) ug/mL); Acheme \\  & & & & & (C\({}_{50}=951\) ug/mL); Acheme \\  & & & & & (C\({}_{50}=158\) ug/mL); Acheme-N9 \\  & & & & & (C\({}_{50}=117\) ug/mL). \\ \hline
**Orbchanaceae** & & & & & \\ \hline \multirow{4}{*}{_Cistanucle phelypaa_ (L.) [PERSON]} & \multirow{4}{*}{Flowers, stems and roots} & \multirow{4}{*}{Ethyl acetate, acetone, ethanol and water, overnight stirring} & \multirow{4}{*}{Flowers: tubuloside, and barissoside Sems: tubuloside Roots: echinacoside} & \multirow{4}{*}{Flowers: tubuloside and barissoside enzyme inhibition} & \multirow{4}{*}{Flowers: AchE and BuChE (1.72 mg GALAE/g). Acheme (1.30 mg GALAE/g). Acheme (1.47 mg GALAE/g). Acheme Roots: AchE} & \multirow{4}{*}{Flowers: tubuloside, glucose Sems: AchE and BuChE enzymes inhibition} & \multirow{4}{*}{ArchE and BuChE enzymes: Acheme (1.30 mg GALAE/g). Acheme (1.47 mg GALAE/g). Acheme Roots: AchE} & \multirow{4}{*}{Flowers: AchE (1.72 mg GALAE/g). Acheme (1.72 mg GALAE/g). Acheme (1.30 mg GALAE/g). Acheme (1.47 mg GALAE/g). Acheme Roots: AchE} & \multirow{4}{*}{Flowers: AchE (1.72 mg GALAE/g). Acheme (1.30 mg GALAE/g). Acheme (1. \begin{table}
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**Family/Species** & **Plant Organs** & **Extract** & **Main Constituents** & **Assay** & **Main Results** & **Reference** \\ \hline
**Plumbaginaceae** & & & & & & AChE: Ethanol, Flowers \\ \hline _Armeria pungers_ (Link) [PERSON] and Link) & Flowers, bedunces and leaves & Ethyl acetate, acetone, ethanol and water overnight under stirring, at room temperature & Catechin & AChE and BuCh enzyme inhibition & Ethanol, Leaves (\(\mathrm{C_{S0}}=221\) mg/mL); (\(\mathrm{C_{S0}}=90.3\) mg/mL); Water, Leaves (\(\mathrm{C_{S0}}=87.6\) mg/mL) & [45] \\ \hline _Armeria pungers_ (Link) [PERSON] and Link) & Flowers, bedunces and leaves & Ethyl acetate, acetone, ethanol and water overnight under stirring, at room temperature & Fraction 3: p-comunic acid, catechchin and epigallocatechin-3-glucose spectroscopy (anti-spectroscopy (anti-amyloidogenic activity) & [46] \\ \hline _Limoninstrum_ & & & & & \\ _gavoratim_ Boiss & Aerial parts & Aqueous acetone (64, \(\mathrm{\SIUnitSymbolMicro m}\)/\(\mathrm{\SIUnitSymbolMicro m}\)) extraction followed by partitioning with petroleum ether and ethyl acetate & Fraction 4: gallo-catechin, snapic acid, N-E-catechin and Thymine and & Thioflavin T fluorescence spectroscopy (anti-amyloidogenic activity) & Fractions 3 and 4: inhibition percentage of 57 and 54\%, respectively (at 10 mg/mL) & [47] \\ \hline _Limoninstrum_ & & & & & \\ _gavoratim_ Boiss & Aerial parts & Aqueous acetone (64, \(\mathrm{\SIUnitSymbolMicro m}\)/\(\mathrm{\SIUnitSymbolMicro m}\)) extraction followed by partitioning with petroleum ether and ethyl acetate & Hydroybenzoic acids (gallic and syringic acid), hydroxycinamic acid, N-E-catechin and Thymine acid,  
A total of sixteen species belonging to nine different plant families have been described with in vitro neuroprotective properties, where Chenopodiaceae and Juncaceae families emerged as the most represented. The aerial parts, including stems, leaves, and flowers are the plant organs that have been the focus of most investigations. In turn, a variety of extraction methods and solvents were used, with the most used in the studies being maceration and magnetic stirring, with solvents including methanol, ethanol, and aqueous acetone. Moreover, it is evident that the most active plants used for mental health treatments primarily contain a diverse array of metabolites, with phenolic compounds, flavonoids, and terpenids being the major components.