## 3 Discussion
\begin{table}
\begin{tabular}{c c c c c c} \hline \hline \multirow{2}{*}{**No.**} & \multirow{2}{*}{**Protein ID**} & \multirow{2}{*}{**Protein Name**} & \multicolumn{4}{c}{**Log2 Protein Abundance**} \\ \cline{3-6}  & & & **WT0** & **RII-2\_0** & **WT24** & **RII-2\_24** \\ \hline
1 & Q5V70 & Auxin efflux carrier component 3a & 0 & 0.00 & 0 & 13.89 \\
2 & Q942P9 & Probable protein phosphatase 2C 1 & 0 & 0.00 & 0 & 13.40 \\
3 & Q8H3C8 & IAA-amino acid hydrolase LIR1-like 8 & 0 & 0.00 & 0 & 12.32 \\
4 & Q75 KV9 & Transcription factor BHLH148 & 14.86 & 0.00 & 0.00 & 12.16 \\
5 & Q53Q70 & Transcription factor TGA4 & 12.27 & 14.91 & 0.00 & 15.84 \\
6 & Q9 FWX2 & NAC domain-containing protein 7 & 13.61 & 13.03 & 0.00 & 15.28 \\
7 & Q9 FY82 & NAC domain-containing protein 82 & 14.16 & 17.64 & 11.13 & 13.48 \\
8 & Q6K537 & Dof zinc finger protein 3 & 0.00 & 15.55 & 12.77 & 11.53 \\
9 & A4 LBC0 & B3 domain-containing protein LFL1 & 12.15 & 17.90 & 16.00 & 0.00 \\
10 & Q7Y0V7 & Homeobox-leucine zipper protein ROC6 & 12.86 & 16.98 & 15.16 & 0.00 \\
11 & Q6 ZB88 & Transcription factor TGAL10 & 0.00 & 12.66 & 12.05 & 0.00 \\
12 & Q40636 & Expansion-A2 & 14.33 & 0.00 & 0.00 & 13.32 \\
13 & B9 FFA3 & Kinesin-like protein KIN-7E & 15.97 & 14.95 & 15.44 & 17.06 \\
14 & Q5Z7L0 & Beta-galactosidase 9 & 13.81 & 0.00 & 12.71 & 13.43 \\
15 & Q7 XPY5 & Putative beta-glucosidase 15 & 11.39 & 18.11 & 10.45 & 15.45 \\
16 & Q6K669 & Leucine aminopeptidase 2 & 0.00 & 12.06 & 15.04 & 17.61 \\
17 & Q3 EB68 & Endoribonuclease dicer homolog 2 & 13.73 & 18.60 & 14.93 & 16.27 \\
18 & QQDV66 & Pheophophide a oxygenase & 15.81 & 0.00 & 14.65 & 16.10 \\
19 & QOD5R3 & Cysteine-rich receptor-like protein kinase 6 & 14.21 & 19.46 & 0.00 & 14.71 \\
20 & Q6Z8P4 & Plant intracellular Ras-group-related LRR protein 4 & 14.85 & 15.68 & 13.29 & 14.80 \\
21 & Q7X7X4 & Cytochrome P450 & 13.27 & 17.21 & 0.00 & 13.74 \\
22 & P48642 & Glutathione reductase & 15.75 & 15.39 & 15.06 & 0.00 \\
23 & P93407 & Superoxide dismutase & 0.00 & 14.93 & 12.14 & 11.05 \\
24 & Q65 XA0 & Probable glutathione S-transferase DHAR1 & 0.00 & 13.86 & 16.46 & 11.51 \\
25 & B9 FSC8 & Putative 12-oxophytodenoate reductase 11 & 13.27 & 15.73 & 12.51 & 0.00 \\ \hline \hline \end{tabular}
\end{table} 
Table 2: Differentially expressed proteins in wild-type (WT) and _OsVTC1-1_ RII-2 line at 0 and 24 h post inoculation with 10100 isolate. peroxidation caused by ROS. Increased lipid peroxidation was observed in HR cell death after _M. oryzae_ infection in rice [32]. _OsVTC1-1_ gene silencing enhances resistance to _M. oryzae_ by disturbing gene and protein expression in multiple pathways, including defense response and hormone signaling. DEGs and DEPs between WT and _OsVTC1-1_ RI1-2 line at 0 and 24 hpi were identified. Among the up-regulated DEGs associated with defense response, determined in this study and reported in previous studies, include germin-like protein family (GLP), peroxidase, and pathogenesis-related (PR) proteins. GLPs play an essential role in defense against _Aspergillus flavus_[40]. Peroxidases are associated with ROS generation and interacting with plant defense molecules, such as salicylic acid (SA), chitololigosaccharides (COSs), and aromatic monoamines (AMAs) [41]. Additionally, the RNA-seq data revealed that the _peroxidase_ gene was expressed at the highest level at 12 hpi with rice blast fungus in Nipponbare [42]. PR proteins are generated during plant-pathogen interactions, which can inhibit the growth of pathogens [43]. A previous study reported that the expression of the _PR-3_ (At2g43590) gene was induced at 6 and 24 h after inoculation with _Alternaria brassicae_[44].