###### Abstract  
The enrichment of oils with intraceutical bioactive phytomolecules allows the achievement of functional oil-based products of great interest in the food, pharmaceutical, and cosmetic fields. Carotenoids, such as lycopene and \(\beta\)-carotene, are available at a high concentration in tomatoes and tomato waste products, as peels, seeds, and pulp; their recovery is recently attracting growing interest and economic importance in the food industry, and also in consideration of the huge amount of industrial waste produced. The aim of this work is to study the production of an oil functionalized with carotenoids from tomato peels. The extractions were carried out using an innovative process based on the use of commercial Norflurane as solvent in subcritical conditions. Extraction trials were performed on dried tomato peels, with the addition of tomato seeds or wheat germ flour as sources of oily co-solvents, capable of also preserving the biological characteristics of the carotenoids extracted. Although lycopene solubility in Norflurane is quite low, the solvent recirculation and regeneration were allowed to reach a concentration in the oily extracts of approximately 0.3 mg/g\({}_{\text{oil}}\) after 2 h of the process. The enrichment in \(\beta\)-carotene was more pronounced, and concentrations of 0.733 mg/g\({}_{\text{oil}}\) and 0.952 mg/g\({}_{\text{oil}}\) were observed in wheat germ and tomato seed oils, respectively. The results obtained in this study were compared with those obtained by traditional and supercritical CO\({}_{2}\) extraction methods. functional enriched oils; tomato by-products; extraction yield; oleaginous co-matrix; carotenoid solubility; hydrofluorocarbon solvent; fatty acids profile Article  
Recovery of Carotenoids from Tomato Pomace Using a Hydrofluorocarbon Solvent in Sub-Critical Conditions  
[PERSON] [PERSON]; [PERSON]; [PERSON]; [PERSON]; [PERSON] [PERSON]; [PERSON] [PERSON]. a waste of resources. Moreover, these wastes can impact negatively on the environment since they are a potential source of methane, a gas that negatively contributes to global warming [3]. The proper disposal of these abundant residues represents an economical issue for the food industries due to the average cost for their removal. On the other hand, it is possible to evaluate the reuse of this tomato pomace, which could be converted into useful resources: this principle is at the base of bioeconomy, which finds industrial application in bio-refinery. To respect the principles of bioeconomy, tomato wastes are currently reused for animal feeding or as fertilizers, and they have been proposed to produce different products, such as chemicals biocatalysts, biopolymers suitable for different applications and energy production [4]. Tomato contains large amounts of high added-value compounds such as carotenoids (around 90-180 mg/kg of fresh weight), mainly lycopene (80-90% of the total carotenoids) and \(\beta\)-carotene (2-3% of the total carotenoids) [5]. Low amounts of other carotenoids such \(\alpha\)-\(\gamma\)-and \(\varepsilon\)-carotenes, phytoene, phytofluene, neurosporene, and lutein are also present [6]. [PERSON] et al. [7] showed that carotenoids have positive effects on human health due to their strong antioxidant activity. Furthermore, epidemiological studies suggested an important role of lycopene in protecting against cancer and cardiovascular diseases [8; 9]. For these reasons, tomato can be used as a functional ingredient in food formulations, and several studies on its potential functionalization were carried out in order to enhance its beneficial properties and broaden the field of applications in which it can be involved [10; 11; 12; 13]. lycopene (\(\psi\), \(\psi\)-carotene) is an acyclic tetraterpene hydrocarbon with 13 carbon-carbon double bonds, 11 of which are conjugated.