## 3 Results
### Pain Analysis
During the first month, a trend appeared in which BG patients had described a higher level of pain compared to IG patients, except for the first 4 h (T1), 8 h (T2), and 7 days (T9). The maximum pain peak occurred at 24 h (T3) in both treatment groups (BG: 4.366 \(\pm\) 1.947; IG: 3.729 \(\pm\) 2.716). Upon the fifth day (T7), the level of pain decreased, reaching minimum levels (Figure 2). During the fourth month after the initial orthodontic treatment (Table 4), statistically significant differences were observed in pain scores at 4 h (T1) (\(p\) < 0.01), 8 h (T2) (\(p\) < 0.05), 4 days (T6) (\(p\) < 0.05), 5 days (T7) (\(p\) < 0.05), and 7 days (T9) (\(p\) < 0.05). During this month, it was expected that BG patients would report a lower pain score compared to IG patients. The BG patients described their highest pain levels at 24 h (1.381 \(\pm\) 1.265), while the IG patients reported their highest pain score on the visual analog scale at 8 h (1.905 \(\pm\) 1.970). At the fourth month after the initial treatment, BG patients had a new 0.016\" \(\times\) 0.022\" thermal CuNiTi orthodontic archive installed, which likely influenced the pain score in \begin{table}
\begin{tabular}{c c c c c c} \hline \hline \multirow{2}{*}{**Moment (Month 1)**} & \multicolumn{2}{c}{**Brackets (BG) (\(n\) = 70)**} & \multicolumn{2}{c}{**Invasilagin (IG) (\(n\) = 70)**} & \multirow{2}{*}{**} \\ \cline{2-2} \cline{4-5}  & **Mean** & **SD** & **Mean** & **SD** & **\(p\) between Groups** \\ \hline
**T1 \({}^{\text{\textasci{}}}\)** **\(\ast\)** & 1.537 & 1.220 & 2.550 & 2.390 & 0.002 \\ \hline
**T2 \({}^{\text{\textasci{}}}\)** & 3.231 & 1.754 & 3.424 & 2.475 & 0.606 \\ \hline
**T3 \({}^{\text{\textasci{}}}\)** & 4.366 & 1.947 & 3.729 & 2.716 & 0.108 \\ \hline
**T4 \({}^{\text{\textasci{}}}\)** & 3.679 & 1.906 & 3.003 & 2.521 & 0.072 \\ \hline
**T5 \({}^{\text{\textasci{}}}\)** & 3.351 & 1.588 & 2.259 & 2.121 & 0.001 \\ \hline
**T6 \({}^{\text{\textasci{}}}\)** & 2.328 & 1.447 & 1.557 & 1.703 & 0.004 \\ \hline
**T7 \({}^{\text{\textasci{}}}\)** & 1.649 & 1.387 & 1.201 & 1.546 & 0.071 \\ \hline
**T8 \({}^{\text{\textasci{}}}\)** & 1.119 & 1.197 & 1.006 & 1.561 & 0.615 \\ \hline
**T9 \({}^{\text{\textasci{}}}\)** & 0.425 & 0.698 & 0.629 & 1.235 & 0.241 \\ \hline \hline \end{tabular}  
* Statistically significant at \(p\) < 0.01. The different superscript letters in the rows indicate which groups show significant differences according to the Bonferroni post hoc tests.  
\end{table} 
Table 3: Comparison of pain between both treatment groups during the first month of treatment. Figure 2: Comparison of pain between both treatment groups during the first month of treatment. this group of patients. In addition, in this month, from the fifth day (T7) after the check-up appointment, the level of pain decreased to almost zero (Figure 3). At 8 months (Table 5), statistically significant differences were observed in pain scores at 4 h (T1) (\(p<0.01\)), 5 days (T7) (\(p<0.05\)), and 7 days (T9) (\(p<0.05\)). At this time, IG (\(p<0.05\)) patients described higher levels of pain compared to BG patients, except for the first 24 h (T3) and at 3 days (T5). In addition, as previously stated, the archive was changed in BG patients with multibracket fixed appliances. This arch change may have influenced pain scores, as seen in Table 5.  
As in the fourth month, the peak of maximum pain in the BG patients was at 24 h (1.5 \(\pm\) 1.285) and, in the IG patients, at 8 h (1.401 \(\pm\) 1.722). From the fifth day (T7), the pain is described by the patients was almost nil (Figure 4).