## 3 Results
### The Post-Treatment Assessment and Comparison to Healthy Controls  
The comparison between the myotonometer parameters of the Parkinson's disease patients (post medical treatment, drug administration) and the control group (second measurement) are presented in Table 7 (data of the all four muscle groups). Frequency, stiffness and decrement had significantly increased values for the patients' group. For all the four assessed muscles, frequency was significantly higher in Parkinson's disease patients one hour after medication intake. Moreover, stiffness, relaxation and creep had increased values in the major pectoralis. Stiffness was also significantly higher in biceps brachialis, while for the lower limb muscle groups, decrement had greater values (Tables 8-11). \begin{table}
\begin{tabular}{c c c c} \hline \hline \multirow{2}{*}{**Myoton PRO Parameters**} & \multicolumn{2}{c}{**Parkinson’s Disease**} & \multirow{2}{*}{**Control Group (N = 42)**} & \multirow{2}{*}{\(p\)**} \\  & **Patients (N = 49)** & & \\ \hline Frequency (Hz), mean (SD) & 18.99 (3.08) & 17.70 (3.29) & **0.02** \\ Stiffness (N/m), mean (SD) & 393.16 (7.48) & 336.50 (67.00) & 0.04 \\ Decrement, mean (SD) & 1.67 (0.72) & 1.21 (0.42) & **0.001** \\ Relaxation (ms), mean (SD) & 15.95 (3.92) & 15.15 (3.48) & 0.15 \\ Creep, mean (SD) & 1.03 (0.25) & 0.97 (0.22) & 0.12 \\ \hline \hline \end{tabular}  
N: number of patients; SD: standard deviation; Bold values: \(p<0.05\) indicates statistical significance.  
\end{table} 
Table 6: Myotonometer parameters of anterior tibialis in Parkinson’s disease patients (pre drug administration) and the control group (first measurement). \begin{table}
\begin{tabular}{c c c c} \hline \hline \multirow{2}{*}{**Myoton PRO Parameters**} & \multicolumn{2}{c}{**Parkinson’s Disease**} & \multirow{2}{*}{**Control Group (N = 42)**} & \multirow{2}{*}{\(p\)**} \\  & **Patients (N = 49)** & & \\ \hline Frequency (Hz), mean (SD) & 13.38 (2.70) & 11.84 (1.92) & **0.001** \\ Stiffness (N/m), mean (SD) & 239.62 (26.81) & 228.90 (34.17) & **0.04** \\ Decrement, mean (SD) & 2.00 (0.49) & 1.86 (0.35) & 0.06 \\ Relaxation (ms), mean (SD) & 26.35 (4.14) & 28.12 (4.72) & **0.02** \\ Creep, mean (SD) & 1.64 (0.26) & 1.74 (0.29) & **0.04** \\ \hline \hline \end{tabular}  
N: number of patients; SD: standard deviation; Bold values: \(p<0.05\) indicates statistical significance.  
\end{table} 
Table 4: Myotonometer parameters of biceps brachialis in Parkinson’s disease patients (pre drug administration) and the control group (first measurement). \begin{table}
\begin{tabular}{c c c c} \hline \hline \multirow{2}{*}{**Myoton PRO Parameters**} & \multicolumn{2}{c}{**Parkinson’s Disease**} & \multirow{2}{*}{**Control Group (N = 42)**} & \multirow{2}{*}{\(p\)**} \\  & **Patients (N = 49)** & & \\ \hline Frequency (Hz), mean (SD) & 16.64 (4.36) & 15.14 (3.64) & **0.001** \\ Stiffness (N/m), mean (SD) & 393.16 (7.48) & 302.03 (88.06) & **0.02** \\ Decrement, mean (SD) & 1.92 (0.59) & 1.67 (0.49) & **0.001** \\ Relaxation (ms), mean (SD) & 20.53 (7.65) & 21.49 (6.78) & 0.26 \\ Creep, mean (SD) & 1.30 (0.46) & 1.34 (0.41) & 0.35 \\ \hline \hline \end{tabular}  
N: number of patients; SD: standard deviation; Bold values: \(p<0.05\) indicates statistical significance.  
\end{table} 
Table 7: Myotonometer parameters (all muscle data) of the Parkinson’s disease patients (post medical treatment) and the control group (second measurement).