## 3 Results
### Organic Filters
#### 3.1.1 UVB Filters  
UV filters allowed in cosmetic products in Europe are regulated in Annex VI of Cosmetics Regulation (EC) No. 1223/2009 [63].  
* Octyldimethyl PABA or Padimate O: EDC (estrogenic), liberator of free radicals, allergen reactions, ecotoxixin and environmental pollutant. Always avoid (EWG sec 5 fair)
- Ethylhexyl triazone (octyl triazone): Not authorized in the USA. Increases the effectiveness of other filters. Free radical released in sunlight. Very little data. Prudence (EWG 1 None)
* Octinoxate (Octyl Methoxycinnamate, OMC, Ethylhexyl Methoxycinnamate, EHMC): confirmed EDC, persistent and bioaccumulative, is absorbed through the skin and can increase the absorption of other substances. It appears in breast milk. Ecotoxic. One of the most problematic filters today. Banned in Denmark in creams for children. It pollutes rivers and affects the populations of fish and other aquatic animals. It appears in tap water and even some bottled water. Always avoid (EWG 6 limited)
- Cinoxato (2-Ethoxyethyl-P-Methoxycinnamate): In disuse. There is little data on its safety. Avoid as a precaution (EWG 3 limited)
* Octisalate (ethylhexyl salicate, 2-Ethylhexyl 2-Hydroxybenzoate): It is quite safe, it is frequently used in association with Avobenzene to extend the duration of protection. Ecotoxin. Today, it is an acceptable chemical filter (EWG sec 3)
- Homosalate (3,3,5-Trimethyl-Salicylate Cyclohexanol; 3,3,5-Trimethylcyclohexyl 2-Hydroxybenzoate): Highly polluting, weak endocrine disruptor, decomposes with light into oxidizing substances that are harmful to the skin. Increases the absorption of other substances. Avoid (EWG 4 limited)
* Octocrylene or octocrilene (CAS n. 6197-30-4) (2-ethylhexyl1 2-cyano-3,3-diphenyl-2-propenoate; 2-ethylhexyl 2-cyano-3,3-diphenylxylate or the 2-ethylhexyl ester of 2  
Figure 1: Type of filters and its mechanism of action.  
cyano-3,3-diphenyl acrylic acid): It is an organic ultraviolet (UV) filter with an aromatic structure, which absorbs mainly UVB radiation and short UVA wavelengths [64]. It is used in sunscreens with other UV filters to provide an adequate sun protection factor (SPF) due to its UV radiation absorption properties [65]. According to regulation, octocylene is authorized as a UV filter in cosmetic formulations at a maximum concentration of 10.0% in acid form in Europe (Annex VI/10). Octorylene seems to have endocrine disrupting activity and may cause allergies and/or (photo)allergies. It is included in the list elaborated in 2019 by the European Commission that collected 14 ingredients with potential disrupting properties used in cosmetic products [66].
* Ensiluzole: (2-Pheny 1H-benzimidazole 5-Sulfonic acid, PBSA): In contact with the sun, it produces free radicals that can damage DNA and potentially cause skin cancer. Avoid if possible (EWG 3 limited)
* 4-MBC (4-Methylbenzylidene Camphor) (1,7,7-Trimethyl-3- [(4-Methylphenyl) Methylene] Bicyclo [2.2.1] Heptan-2-On)): EDC, persistent and bioaccumulative. Not authorized in the US for sun creams. Possible thyroid toxicity. Important environmental contaminant, affects aquatic populations. Always avoid. (EWG 7 fair)  
Some studies have reported that Sulphonated compounds act as DNA alkylating agents, and genotoxic agents in bacterial and mammalian cells [67].