## 2 Case Report
### Diagnosis and Etiology
\begin{table}
\begin{tabular}{c c c c c c} \hline
**Variables** & **Norm** & **T1** & **T2 (6 Months)** & **T3 (15 Months)** & **T4 (22 Months)** \\ \hline SNA (\({}^{\circ}\)) & 82.4 & 81.7 & 81.7 & 81.4 & 81.4 \\ \hline SNB (\({}^{\circ}\)) & 80.4 & 85.4 & 85.4 & 84.6 & 84.6 \\ \hline ANB (\({}^{\circ}\)) & 2.0 & \(-\)3.7 & \(-\)3.7 & \(-\)3.2 & \(-\)3.2 \\ \hline AO-BO (mm) & \(-\)2.2 & \(-\)9.8 & \(-\)8.5 & \(-\)6.6 & \(-\)5.2 \\ \hline APDI & 85.9 & 92.4 & 92.3 & 91.4 & 90.8 \\ \hline ODI & 73.3 & 55.8 & 55.2 & 55.5 & 55.1 \\ \hline SN-MP (\({}^{\circ}\)) & 30.2 & 29.5 & 30.0 & 31.2 & 31.2 \\ \hline AFH (mm) & 136.4 & 140.8 & 141.1 & 143.0 & 142.8 \\ \hline PFH (mm) & 95.4 & 99.2 & 98.5 & 99.2 & 98.9 \\ \hline FHR (\%) & 70.2 & 70.5 & 69.8 & 69.4 & 69.3 \\ \hline U1 to FH (\({}^{\circ}\)) & 116.0 & 127.6 & 121.8 & 126.5 & 127.5 \\ \hline IMPA (\({}^{\circ}\)) & 96.6 & 86.7 & 82.1 & 72.5 & 76.2 \\ \hline U1 to L1 (\({}^{\circ}\)) & 124.0 & 123.0 & 132.8 & 136.7 & 133.0 \\ \hline MxOP to FH (\({}^{\circ}\)) & 14.0 & \(-\)3.5 & 1.5 & 2.2 & 1.1 \\ \hline MnOP to FH (\({}^{\circ}\)) & 14.0 & 7.8 & \(-\)0.9 & \(-\)0.9 & 0.3 \\ \hline UL to EL (mm) & 1.0 & \(-\)4.8 & \(-\)2.4 & \(-\)2.8 & \(-\)2.7 \\ \hline LL to EL (mm) & 1.0 & \(-\)1.3 & 1.4 & 0.3 & \(-\)1.1 \\ \hline NLA (\({}^{\circ}\)) & 100.0 & 99.5 & 91.6 & 92.7 & 92.8 \\ \hline Z angle (\({}^{\circ}\)) & 75.0 & 85.7 & 81.0 & 83.1 & 85.9 \\ \hline \end{tabular}
\end{table} 
Table 1: Two-dimensional cephalometric measurements. \begin{table}
\begin{tabular}{c c c} \hline \hline
**Variables** & **T1 (x, y, z)** & **T3 (x, y, z)** \\ \hline U1 MP & (\(-\)1.95, \(-\)4.31, \(-\)78.07) & (\(-\)2.04, \(-\)3.66, \(-\)81.29) \\ \hline L1 MP & (\(-\)6.22, \(-\)6.41, \(-\)85.15) & (\(-\)1.82, \(-\)0.90, \(-\)79.89) \\ \hline RU6 CP (right) & (\(-\)31.94, 21.69, \(-\)79.64) & (\(-\)31.43, 22.41, \(-\)80.25) \\ \hline LU6 CP (left) & (26.86, 23.34, \(-\)79.75) & (25.86, 23.42, \(-\)81.27) \\ \hline RL6 CP (right) & (\(-\)27.92, 18.54, \(-\)80.58) & (\(-\)28.35, 20.14, \(-\)79.59) \\ \hline LL6 CP (left) & (17.50, 15.99, \(-\)82.42) & (22.63, 21.56, \(-\)79.98) \\ \hline Point A & (\(-\)2.16, 3.21, \(-\)57.25) & (\(-\)1.03, 3.25, \(-\)58.82) \\ \hline Point B & (\(-\)6.81, \(-\)2.83, \(-\)104.40) & (\(-\)4.98, \(-\)1.87, \(-\)103.55) \\ \hline Pogonion & (\(-\)8.04, \(-\)5.77, \(-\)117.50) & (\(-\)6.13, \(-\)5.20, \(-\)119.91) \\ \hline Menton & (\(-\)7.70, \(-\)13.36, \(-\)125.09) & (\(-\)5.46, 0.09, \(-\)126.68) \\ \hline Gonion (right) & (\(-\)50.94, 67.55, \(-\)94.62) & (\(-\)49.93, 69.01, \(-\)94.76) \\ \hline Gonion (left) & (43.92, 65.31, \(-\)91.65) & (44.47, 65.37, \(-\)93.14) \\ \hline Stomion & (\(-\)2.69, \(-\)14.54, \(-\)77.29) & (\(-\)1.37, \(-\)14.40, \(-\)80.00) \\ \hline UL & (\(-\)2.05, \(-\)19.23, \(-\)71.22) & (\(-\)0.84, \(-\)19.52, \(-\)72.61) \\ \hline LL & (\(-\)3.41, \(-\)22.19, \(-\)84.05) & (\(-\)0.64, \(-\)20.06, \(-\)87.60) \\ \hline \hline \end{tabular}  
* T1, pretreatment, T3, posttreatment (15 months); U1 MP, the midpoint of maxillary central incisal tips; L1 MP, the midpoint of mandibular central incisal tips; R, right; L, left; U6 CP, mesiboulocal cuspal point of maxillary first molar; L6 CP, mesiboulocal cuspal point of mandibular first molar; UL, most anterior point of upper lip; LL, most anterior point of the lower lip.  
\end{table} 
Table 2: Three-dimensional cephalometric measurements. Figure 4: Pretreatment CBCT images using 3-dimensional coordinates. (**A**) Frontal image; (**B**) Submentovertex image (arrow means mandibular yawing); (**C**) Sagittal image (right side); (**D**) Sagittal image (left side).