## 3 Results
### Baseline Characteristics of the Study
\begin{table}
\begin{tabular}{c c c c c c c c} \hline  & \multicolumn{2}{c}{**Overall Cohort**} & \multicolumn{2}{c}{**sPAP \textless{} 40 mmHgg**} & \multicolumn{2}{c}{**sPAP \textgreater{} 40 mmHgg**} & \\  & \multicolumn{2}{c}{**n = 85**} & \multicolumn{2}{c}{**n = 32**} & \multicolumn{2}{c}{**n = 53**} & \\ \hline \multicolumn{2}{c}{**Clinical Data**} & & & & & & \multicolumn{2}{c}{_p-value_} \\ \hline Age (years)—mean \(\pm\) SD & 82.34 & 5.41 & 81.50 & 5.48 & 83.25 & 5.09 & 0.140 \\ Gender (male)—\% (n) & 50.60 & (43) & 50.00 & (16) & 50.90 & (27) & 0.933 \\ Weight (kg)—mean \(\pm\) SD & 72.39 & 12.50 & 73.09 & 14.77 & 70.59 & 8.44 & 0.556 \\ Height (cm)—mean \(\pm\) SD & 165.75 & 8.07 & 165.14 & 9.19 & 166.75 & 6.02 & 0.518 \\ BMI (kg/m\({}^{2}\))—mean \(\pm\) SD & 26.30 & 4.09 & 27.08 & 4.49 & 25.14 & 3.03 & 0.122 \\ NYHA—median \(\pm\) IQR & 3.00 & 0.75 & 3.00 & 1.00 & 3.00 & 1.00 & 0.624 \\ STSScore—mean \(\pm\) SD & 3.08 & 1.62 & 2.56 & 1.29 & 3.29 & 1.51 & **0.025** \\ \hline \multicolumn{2}{c}{**Concomitant Disease**} & & & & & & \multicolumn{2}{c}{_p-value_} \\ \hline Diabetes mellitus—\% (n) & 24.70 & (21) & 21.90 & (7) & 26.40 & (14) & 0.638 \\ Arterial Hypertension—\% (n) & 77.60 & (66) & 78.10 & (25) & 83.00 & (44) & 0.576 \\ CVD—\% (n) & 61.20 & (52) & 59.40 & (19) & 62.30 & (33) & 0.791 \\ CVD—1 vessel—\% (n) & 14.10 & (12) & 15.60 & (5) & 13.20 & (7) & 0.756 \\ CVD—2 vessels—\% (n) & 12.90 & (11) & 9.40 & (3) & 15.1 & (8) & 0.447 \\ CVD—3 vessels—\% (n) & 23.50 & (20) & 21.90 & (7) & 24.50 & (13) & 0.780 \\ Myocardial infarction—\% (n) & 4.70 & (4) & 3.10 & (1) & 5.70 & (3) & 0.593 \\ Atrial fibrillation—\% (n) & 32.90 & (28) & 12.50 & (4) & 45.30 & (24) & **0.002** \\ Malignancy—\% (n) & 22.40 & (19) & 21.90 & (7) & 22.60 & (12) & 0.943 \\ Stroke—\% (n) & 9.40 & (8) & 9.40 & (3) & 9.40 & (5) & 0.993 \\ PAD—\% (n) & 9.40 & (8) & 3.10 & (1) & 13.20 & (7) & 0.123 \\ COPD—\% (n) & 8.20 & (7) & 9.40 & (3) & 7.50 & (4) & 0.766 \\ Pacemaker—\% (n) & 3.50 & (3) & 0.00 & (0) & 5.70 & (3) & 0.171 \\ \hline \multicolumn{2}{c}{**Echocardiography**} & & & & & \multicolumn{2}{c}{_p-value_} \\ \hline LVEF (\%)—mean \(\pm\) SD & 53.42 & 9.99 & 55.25 & 6.17 & 52.00 & 11.50 & 0.099 \\ LVEDD (mm)—mean \(\pm\) SD & 4.69 & 0.61 & 4.63 & 0.71 & 4.66 & 0.53 & 0.838 \\ IVSd (mm)—mean \(\pm\) SD & 13.36 & 2.50 & 13.23 & 2.28 & 13.54 & 2.04 & 0.523 \\ AV Vmax (m/s)—mean \(\pm\) SD & 4.43 & 0.55 & 4.34 & 0.61 & 4.43 & 0.52 & 0.535 \\ AV dPmean (mmHg)—mean \(\pm\) SD & 49.55 & 11.52 & 46.55 & 11.39 & 50.61 & 11.83 & 0.147 \\ AV dPmax (mmHg)—mean \(\pm\) SD & 81.61 & 20.15 & 77.59 & 19.49 & 82.67 & 21.00 & 0.299 \\ sPAP (mmHg)—mean \(\pm\) SD & 46.36 & 17.49 & 31.75 & 6.86 & 54.42 & 15.10 & **<0.001** \\ TAPSE (mm)—mean \(\pm\) SD & 22.25 & 3.78 & 23.12 & 3.21 & 20.95 & 4.06 & **0.017** \\ AVI \(\geq\) II—\% (n) & 16.50 & (14) & 21.90 & (7) & 13.20 & (7) & 0.561 \\ MVI \(\geq\) II—\% (n) & 41.20 & (35) & 34.40 & (11) & 45.30 & (24) & 0.304 \\ TVI \(\geq\) II—\% (n) & 29.40 & (25) & 12.50 & (4) & 39.60 & (21) & 0.007 \\ \hline \multicolumn{2}{c}{**Laboratory data**} & & & & & \multicolumn{2}{c}{_p-value_} \\ \hline Creatinine (mg/dL)—median \(\pm\) IQR & 1.00 & 0.37 & 0.95 & 0.30 & 1.10 & 0.50 & **0.002** \\ BNP (pg/mL)—median \(\pm\) IQR & 1599.50 & 3117.45 & 1122.50 & 1017.53 & 3162.00 & 4440.00 & **0.001** \\ cTnI (pg/mL)—median \(\pm\) IQR & 21.00 & 21.00 & 16.00 & 15.50 & 31.00 & 41.00 & **0.002** \\ Hkt (\%)—median \(\pm\) IQR & 39.60 & 7.18 & 41.20 & 5.75 & 37.40 & 8.50 & **0.037** \\ Hb (g/dL)—median \(\pm\) IQR & 12.95 & 2.53 & 13.05 & 1.78 & 12.30 & 3.40 & 0.052 \\ CK (U/L)—median \(\pm\) IQR & 67.50 & 74.75 & 77.00 & 115.50 & 59.00 & 71.00 & 0.492 \\ \hline \end{tabular}
\end{table} 
Table 1: Baseline characteristics of study cohort.