## 3 Results
\begin{table}
\begin{tabular}{c c c c c c c c} \hline \multirow{2}{*}{**Indicators**} & \multirow{2}{*}{**Norm (\(\mu\) = 10)**} & \multirow{2}{*}{**Day 7**} & \multicolumn{3}{c}{**Day 14**} \\  & & & \multicolumn{3}{c}{**Main Groups**} & \multicolumn{3}{c}{**Main Groups**} \\  & & & **Ia** & **IIa** & **(\(\mu\) = 7)** & **Ia** & **IIa** \\  & & & **(\(\mu\) = 7)** & **(\(\mu\) = 7)** & **(\(\mu\) = 7)** & **(\(\mu\) = 7)** \\ \hline Erythrocytes, T/1 & 9.82 \(\pm\) 0.07 & 7.40 \(\pm\) 0.07 \(\,{}^{*}\) & 8.95 \(\pm\) 0.20 & 7.15 \(\pm\) 0.16 \(\,{}^{*}\) & 6.08 \(\pm\) 0.4 \(\,{}^{*}\) & 9.66 \(\pm\) 0.16 & 6.28 \(\pm\) 0.15 \(\,{}^{*}\) \\ Leukocytes, G/1 & 7.40 \(\pm\) 0.16 & 14.60 \(\pm\) 0.57 \(\,{}^{*}\) & 11.80 \(\pm\) 0.18 \(\,{}^{*}\) & 16.10 \(\pm\) 0.25 \(\,{}^{*}\) & 16.30 \(\pm\) 0.52 \(\,{}^{*}\) & 8.50 \(\pm\) 0.20 & 16.15 \(\pm\) 0.41 \(\,{}^{*}\) \\ Haemoglobin, G/1 & 114.0 \(\pm\) 2.37 & 105.0 \(\pm\) 2.93 \(\,{}^{*}\) & 106.0 \(\pm\) 2.79 & 104.0 \(\pm\) 3.83 \(\,{}^{*}\) & 102.0 \(\pm\) 2.50 \(\,{}^{*}\) & 112.0 \(\pm\) 1.68 & 101.0 \(\pm\) 5.48 \(\,{}^{*}\) \\ \hline \end{tabular}  
* \(p\) < 0.05—probability of difference of indicators with values to the norm.  
\end{table} 
Table 3: Haematopoietic parameters during the progression of Ehrlich ascites carcinoma under the treatment with the _Filipendula vulgaris_ extracts on the 7 th and 14 th day. When treating animals of the Ia main group with the _F. vulgaris_ aqueous-alcoholic extract, normalisation of the content of erythrocytes and haemoglobin was observed already on the 7 th day and was maintained at this level until the end of the experiment. The number of leukocytes in the blood normalised only on the 14 th day of the study. The treatment with the _F. vulgaris_ aqueous extract in animals of the IIa main group showed a significantly weaker effect. The studied indicators of the content of erythrocytes, leukocytes, and haemoglobin almost did not differ from the indicators established in the control group and at the end of the experiment did not return to the physiological norm. The development of Ehrlich ascites carcinoma in the control group of mice caused a significant decrease in the activity of such enzymes as ceruloplasmin, catalase, and iron saturation of transferrin throughout the experiment (Table 4), which indicated a significant depletion of the antioxidant system in the animal body. Under the influence of treatment with the _F. vulgaris_ aqueous-alcoholic extract in the Ia main group, the activity of catalase and iron saturation of transferrin normalised already on the 7 th day of the experiment, while the activity of ceruloplasmin gradually increased and on the 14 th day of the study corresponded to the physiological norm. With intra-abdominal administration of the _F. vulgaris_ aqueous extract to mice of the IIa main group throughout the entire study period, no positive effect was found in reducing the activity of the studied enzymes. \begin{table}
\begin{tabular}{c c c c c c c c} \hline \hline  & & & & \multicolumn{3}{c}{**Day 7**} & \multicolumn{3}{c}{**Day 14**} \\  & & & & **Main Groups** & & & **Main Groups** \\  & & & & **Ia** & & **IIa** & & **Ia** \\  & & & **(_n = 7_)** & & & **(_n = 7_)** & & **(_n = 7_)** \\ \hline Ceruloplasmin, & & & & & & & & \\ conventional units & 16.23 \(\pm\) 0.37 & 14.58 \(\pm\) 0.63 * & 14.28 \(\pm\) 0.52 * & 11.50 \(\pm\) 0.51 * & 12.56 \(\pm\) 0.46 * & 15.10 \(\pm\) 0.47 & 11.28 \(\pm\) 0.49 * \\ Transferrin, & & & & & & & \\ conventional units & 0.18 \(\pm\) 0.003 & 0.15 \(\pm\) 0.004 * & 0.16 \(\pm\) 0.006 & 0.14 \(\pm\) 0.004 * & 0.14 \(\pm\) 0.004 * & 0.17 \(\pm\) 0.004 & 0.14 \(\pm\) 0.006 * \\ Catalase, mg H\({}_{2}\)O\({}_{2}\)/mL & 4.45 \(\pm\) 0.15 & 3.45 \(\pm\) 0.10 * & 4.08 \(\pm\) 0.15 & 3.58 \(\pm\) 0.11 * & 3.48 \(\pm\) 0.15 * & 4.28 \(\pm\) 0.14 & 3.28 \(\pm\) 0.4 * \\ \hline \hline \end{tabular}  
* \(p\) < 0.05—probability of difference between indicators and normal values.  
\end{table}