## 3 Results
\begin{table}
\begin{tabular}{c c c c c c c c} \hline  & **Group 1** & **Group 2** & **Group 3** & **Group 4** & **Group 5** & **Group 6** & \({}^{a}\)_p_ \\ \cline{2-8}  & **Mean \(\pm\) sd** & **Mean \(\pm\) sd** & **Mean \(\pm\) sd** & **Mean \(\pm\) sd** & **Mean \(\pm\) sd** & **Mean \(\pm\) sd** & \\ \hline Baseline & 0.043 \(\pm\) 0.009 & 0.060 \(\pm\) 0.004 & 0.083 \(\pm\) 0.005 & 0.086 \(\pm\) 0.006 & 0.094 \(\pm\) 0.005 & 0.098 \(\pm\) 0.006 & \(<\)0.001 ** \\
1 st day & 0.047 \(\pm\) 0.011 & 0.072 \(\pm\) 0.003 & 0.089 \(\pm\) 0.007 & 0.097 \(\pm\) 0.006 & 0.106 \(\pm\) 0.003 & 0.113 \(\pm\) 0.004 & \(<\)0.001 ** \\
2 nd day & 0.053 \(\pm\) 0.013 & 0.080 \(\pm\) 0.006 & 0.095 \(\pm\) 0.007 & 0.105 \(\pm\) 0.005 & 0.113 \(\pm\) 0.004 & 0.125 \(\pm\) 0.009 & \(<\)0.001 ** \\
7 th day & 0.069 \(\pm\) 0.006 & 0.084 \(\pm\) 0.005 & 0.103 \(\pm\) 0.006 & 0.115 \(\pm\) 0.007 & 0.120 \(\pm\) 0.004 & 0.131 \(\pm\) 0.012 & \(<\)0.001 ** \\
30 th day & 0.079 \(\pm\) 0.006 & 0.103 \(\pm\) 0.008 & 0.117 \(\pm\) 0.004 & 0.129 \(\pm\) 0.003 & 0.139 \(\pm\) 0.006 & 0.157 \(\pm\) 0.009 & \(<\)0.001 ** \\ \hline \({}^{b}\)_p_ & \(<\)0.001 ** & \(<\)0.001 ** & \(<\)0.001 ** & \(<\)0.001 ** & \(<\)0.001 ** & \(<\)0.001 ** & \(<\)0.001 ** \\ \hline
**Post hoc** & **Mean \(\pm\) sd** & **Mean \(\pm\) sd** & **Mean \(\pm\) sd** & **Mean \(\pm\) sd** & **Mean \(\pm\) sd** & **Mean \(\pm\) sd** & \({}^{a}\)_p_ \\ \hline Baseline-1 st day & 0.004 \(\pm\) 0.003 & 0.012 \(\pm\) 0.003 ** & 0.007 \(\pm\) 0.005 & 0.011 \(\pm\) 0.006 * & 0.012 \(\pm\) 0.003 ** & 0.016 \(\pm\) 0.006 ** & \(<\)0.001 ** \\ Baseline-2 nd day & 0.011 \(\pm\) 0.006 * & 0.020 \(\pm\) 0.005 ** & 0.012 \(\pm\) 0.006 * & 0.019 \(\pm\) 0.006 ** & 0.019 \(\pm\) 0.005 ** & 0.027 \(\pm\) 0.010 ** & 0.001 ** \\ Baseline-7 th day & 0.026 \(\pm\) 0.005 ** & 0.024 \(\pm\) 0.004 ** & 0.021 \(\pm\) 0.006 ** & 0.029 \(\pm\) 0.009 ** & 0.026 \(\pm\) 0.006 ** & 0.033 \(\pm\) 0.013 ** & 0.094 \\ Baseline-30 th day & 0.037 \(\pm\) 0.007 * & 0.043 \(\pm\) 0.012 ** & 0.035 \(\pm\) 0.002 * & 0.043 \(\pm\) 0.007 * & 0.045 \(\pm\) 0.007 * & 0.059 \(\pm\) 0.012 * & \(<\)0.001 ** \\
1 st-2 nd day & 0.007 \(\pm\) 0.006 & 0.008 \(\pm\) 0.006 & 0.006 \(\pm\) 0.002 ** & 0.007 \(\pm\) 0.002 ** & 0.007 \(\pm\) 0.003 ** & 0.011 \(\pm\) 0.006 * & 0.345 \\
1 st-7 th day & 0.022 \(\pm\) 0.007 ** & 0.012 \(\pm\) 0.004 ** & 0.014 \(\pm\) 0.004 ** & 0.018 \(\pm\) 0.005 ** & 0.015 \(\pm\) 0.005 ** & 0.018 \(\pm\) 0.010 * & 0.051 \\
1 st-30 th day & 0.032 \(\pm\) 0.009 ** & 0.031 \(\pm\) 0.009 ** & 0.028 \(\pm\) 0.005 ** & 0.032 \(\pm\) 0.005 ** & 0.033 \(\pm\) 0.006 ** & 0.044 \(\pm\) 0.007 ** & 0.004 ** \\
2 nd-7 th day & 0.016 \(\pm\) 0.009 * & 0.004 \(\pm\) 0.002 & 0.008 \(\pm\) 0.002 & 0.010 \(\pm\) 0.004 ** & 0.008 \(\pm\) 0.003 * & 0.006 \(\pm\) 0.004 & 0.001 ** \\
2 nd-30 th day & 0.026 \(\pm\) 0.011 ** & 0.023 \(\pm\) 0.012 * & 0.022 \(\pm\) 0.006 ** & 0.024 \(\pm\) 0.003 ** & 0.026 \(\pm\) 0.004 ** & 0.032 \(\pm\) 0.006 * & 0.182 \\
7 th-30 th day & 0.010 \(\pm\) 0.006 & 0.019 \(\pm\) 0.010 * & 0.014 \(\pm\) 0.005 ** & 0.014 \(\pm\) 0.004 ** & 0.018 \(\pm\) 0.003 ** & 0.026 \(\pm\) 0.006 ** & 0.001 ** \\ \hline \end{tabular} \({}^{a}\) One-way ANOVA; \({}^{b}\) Repeated measures ANOVA. * \(p\) \(<\) 0.05, ** \(p\) \(<\) 0.01.  
\end{table} 
Table 1: Evaluations by group and time. \begin{table}
\begin{tabular}{c c c} \hline  & **Tests for Within-Group Effects** \\ \cline{2-4}  & **F** & **_p_ \\ \hline
**Group** & 140.326 & \(<\)0.001 ** \\ \hline \({}^{a}\) indicates \(p\) \(<\) 0.01. \\ \end{tabular}
\end{table} 
Table 3: Pairwise comparisons between groups at five different time points.