## 3 Results
\begin{table}
\begin{tabular}{l l l l l} \hline \hline
**Variable** & **All Patients** & \begin{tabular}{l} **Cystatin C** \\ **<0.95 mg/mL** \\ \end{tabular} & \
\begin{tabular}{l} **Cystatin C** \\ **\(\geq\)0.95 mg/mL** \\ \end{tabular} &
\begin{tabular}{l} **P Value** \\ **\(P\) Value** \\ \end{tabular} \\ \hline
**No. of Patients** & **n = 31** & **n = 14 \({}^{*}\)** & **n = 17** & \\ \hline _Optical coherence tomography_ & & & & \\ Lipid rich plaques, \(n\) median (25 th–75 th) & 6 (4–8) & 6.5 (5–8) & 6 (4–7) & 0.55 \\ Lipid rich plaques with macrophages, n & 2 (4–5) & 4 (3–5) & 4 (2–5) & 0.78 \\ median (25 th–75 th) & 1 (1–2) & 1 (0–3) & 1 (1–3) & 0.32 \\ TCEA, n median (25 th–75 th) & 1.23 (1.12–1.30) & 1.24 (1.15–1.38) & 1.22 (1.09–1.24) & 0.23 \\ Averaged mean TBR in AA, median (25 th–75 th) & 1.84 (1.71–2.04) & 1.95 (1.80–2.21) & 1.79 (1.61–1.93) & 0.05 \\ Averaged mean TBR in DA, median & 1.21 (1.02–1.33) & 1.29 (1.11–1.41) & 1.15 (0.99–1.29) & 0.07 \\ Averaged max TBR in DA, median (25 th–75 th) & 1.74 (1.54–1.92) & 1.82 (1.62–2.11) & 1.61 (1.50–1.84) & 0.06 \\ Number of active slices in AA, median (25 th–75 th) & 11.5 (9–13) & 13 (11–14) & 11 (9–12) & 0.08 \\ Number of active slices in DA, median & 22.5 (6.5–29) & 25 (12–37) & 18 (1–24) & 0.03 \\ CT _scan_ & & & & \\ Coronary calcium score, median (25 th–75 th) & 955 (224–1300) & 1298 (547–1339) & 466 (57–1183) & 0.07 \\ \hline \hline \end{tabular}  
* AA = ascending aorta, DA = descending aorta, TBR = target to background ratio, TCEA = thin cap fibrotheroma.
* 3 patients did not undergo an \({}^{18}\)F-FDG-PET/CT scan.  
\end{table} 
Table 2: Atherosclerotic features as assessed using a multimodality imaging approach according to cystatin C values. Figure 1: Study flow chart. Abbreviations: LVEF = left ventricle ejection fraction, MDRD eGRF = Modified Diet in Renal Disease estimated Glomerular Filtration Rate, \({}^{18}\)F-FDG-PET/CT = \({}^{18}\)F-Fluorodeoxyglucose-Positron Emission Tomography/Computed Tomography, FD-OCT = Frequency Domain-Optical Coherence Tomography, NSTE-ACS = Non-ST-segment Elevation-Acute Coronary Syndrome. \begin{table}
\begin{tabular}{c c c c c c c} \hline \hline
**Variable** & **Odds** & **95\% CI** & **P Value** & \multicolumn{2}{c}{**Adjusted**} & \multicolumn{1}{c}{**95\% CI**} & \multicolumn{1}{c}{**\(P\) Value**} \\  & **Ratio** & & & & **Odds Ratio \({}^{*}\)** & **95\% CI** & **\(P\) Value** \\ \hline \multicolumn{6}{c}{_Optical coherence tomography_} \\ Lipid rich plaques, \(n\) & 0.87 & 0.63–1.20 & 0.40 & 0.85 & 0.58–1.24 & 0.41 \\ Lipid rich plaques with & 1.00 & 0.69–1.47 & 0.98 & 0.82 & 0.64–1.42 & 0.81 \\ macrophages, \(n\) & 1.07 & 0.65–1.77 & 0.77 & 0.98 & 0.58–1.64 & 0.94 \\ T5F-_PET_/CT & & & & & \\ Averaged mean TRB in A, & 0.31 & 0.03–0.62 & 0.35 & 0.07 & 0.0003–14.8 & 0.33 \\ Averaged max TBR in AA, & 0.19 & 0.002–13.7 & 0.45 & 0.19 & 0.01–3.4 & 0.26 \\ Averaged mean TRB in DA, & 0.017 & 0.0002–1.49 & 0.07 & 0.02 & 0.0002–1.06 & 0.053 \\ Averaged max TBR in DA, & 0.07 & 0.004–1.50 & 0.09 & 0.02 & 0.0004–0.89 & 0.044 \\ Number of active slices in AA, & 0.77 & 0.57–1.06 & 0.11 & 0.69 & 0.47–1.02 & 0.069 \\ Number of active slices in DA, & 0.93 & 0.87–1.002 & 0.060 & 0.89 & 0.82–0.98 & 0.025 \\ _CT scan_ & & & & & \\ Coronary calcium score, & 0.99 & 0.99–1.00 & 0.50 & 0.99 & 0.99–1.00 & 0.39 \\ \hline \hline \end{tabular}  
* AA = ascending aorta, DA = descending aorta, TBR = target to background ratio, TCFA = thin cap fibroatheroma.
* Adjusted for the C reactive protein and the Modified Diet in Renal Disease estimated Glomerular Filtration Rate.  
\end{table} 
Table 3: Relation between atherosclerotic features and cystatin C values. Univariable and adjusted odds ratio * for the highest cystatin C group. Figure 2: Representative \({}^{18}\)F-FDG-PET/CT image of thoracic aorta.