## 3 Results
### Antibacterial Activities of Mushroom Extracts against Wild-Type Bacteria
_pseudobulbosa_ against (**a**) _E. faecalis_; (**b**) _S. aureus_; (**c**) _S. epidermidis_; (**d**) _E. coli_; (**e**) _P. aeruginosa_. Figure 2: TLC bioautograms obtained with EtOAc extracts from 1: _Neoboletus erythropus_ #1; 2: _Peziza vesiculosa_; 3: _Scloderma citrium_ #2; 4: _Amanita muscaria_; 5: _Fomitopsis pinicola_; G: gentamicin, against (**a**) _E. faecalis_; (**b**) _S. aureus_; (**c**) _S. epidermidis_. Results from this initial screening on wild-type bacteria have orientated the selection of mushroom extracts to be evaluated against multidrug-resistant strains. We have selected mushrooms according to (i) their antibacterial activity profile, including number of active compounds but also selectivity and effect against Gram-negative bacteria, (ii) the available biomass necessary to further purify active compounds, and (iii) the lack of knowledge regarding mycochemistry, which could increase chances to identify novel bioactive chem \begin{table}
\begin{tabular}{l l c c c c c c c c c c} \hline \hline  & & & & & & & & & & & & & \\ \hline
**Order** & **Mushroom Species** & _Ef_ & _Sa_ & _Se_ & _Ec_ & _Pa_ & _Ef_ & _Sa_ & _Se_ & _Ec_ & _Pa_ \\ \hline Agarclas & _Agaricus bisporus_ & 2 & 3 & 2 & 3 & 0 & **5** & 1 & 1 & 2 & 0 \\  & _Amantia citrina_ & 4 & 3 & 3 & 3 & 1 & 2 & 1 & 1 & 2 & 0 \\  & _Amantia musaria_ & **8** & **7** & 2 & 2 & 1 & 2 & 2 & 2 & 1 & 0 \\  & _Armillaria cquisipes_ var. _pseudobulosa_ & & & & & & & & & & & \\  & _Armillaria ostoyae_ & 1 & 4 & 2 & 3 & 0 & 0 & 0 & 0 & 0 & 0 \\  & _Bolbitius varicolor_ & 2 & 1 & 2 & 1 & 0 & 3 & 1 & 2 & 1 & 0 \\  & _Clitocyhe nebularis_ & 2 & 4 & 2 & 2 & 2 & 0 & 0 & 0 & 0 & 0 \\  & _Cortinarius semisanguineus_ & 1 & 3 & 3 & 0 & 0 & 0 & 0 & 2 & 0 & 0 \\  & _Gymopus luxvirains_ & 4 & 0 & 0 & 1 & 1 & 0 & 0 & 2 & 0 & 0 \\  & _Hypholoma fasciculare_ & 4 & 2 & 3 & 2 & 1 & 5 & 3 & 1 & 0 & 4 \\  & _Macrolepiota procera_ & 5 & 2 & 0 & 0 & 0 & 0 & 0 & 2 & 0 & 0 \\  & _Mycena rosea_ & 4 & 4 & 4 & 2 & 2 & 0 & 0 & 0 & 0 & 0 \\  & _Parasola auricoma_ & 4 & 5 & 2 & 2 & 1 & 0 & 0 & 1 & 0 & 0 \\  & _Pleurotus ostreatus_ & 2 & 4 & 6 & 3 & 1 & 0 & 0 & 1 & 0 & 0 \\  & _Voloplutteus gloiccephalus_ & 11 & 6 & 3 & 3 & 2 & 0 & 0 & 1 & 0 & 0 \\ \[PERSON] & _Hygrohoropsis aurantiaca_ & 5 & 1 & 2 & 2 & 0 & 1 & 0 & 2 & 0 & 0 \\  & _Neoboletus erythropus_ #1 & 6 & 2 & 2 & 2 & 0 & 0 & 0 & 0 & 0 & 0 \\  & _Neoboletus erythropus_ #2 & 4 & 6 & 6 & 1 & 2 & 0 & 3 & 1 & 0 & 0 \\  & _Paxillus involutus_ & 5 & 3 & 1 & 1 & 1 & 0 & 0 & 1 & 0 & 0 \\  & _Scleroderma citriumu_ #1 & 5 & 6 & 3 & 2 & 4 & 0 & 0 & 1 & 0 & 0 \\  & _Scleroderma citriumu_ \#2 & 7 & 6 & 2 & 2 & 2 & 0 & 0 & 1 & 0 & 0 \\  & _Scleroderma citriumu_ \#3 & 4 & 4 & 1 & 3 & 0 & 0 & 5 & 1 & 1 & 0 \\ \hline [PERSON] & _Morchelle esculent_ \#1 & 1 & 2 & 1 & 0 & 1 & 1 & 4 & 0 & 1 & 0 \\  & _Morchelle esculent_ \#2 & 4 & 0 & 4 & 2 & 2 & 0 & 1 & 0 & 0 & 0 \\  & _Peziza vesicidosa_ & 5 & 2 & 1 & 1 & 0 & 2 & 4 & 2 & 1 & 2 \\ \hline [PERSON] & _Fomitopsis pinicola_ & 15 & 10 & 4 & 5 & 3 & 5 & 1 & 8 & 3 & 3 \\  & _Ganoderma aplanatum_ & 4 & 3 & 1 & 1 & 0 & 1 & 4 & 1 & 2 & 0 \\  & _Meripilus giganteus_ & 7 & 4 & 2 & 2 & 0 & 0 & 0 & 2 & 1 & 0 \\  & _Polyporus umbellatus_ & 8 & 3 & 4 & 3 & 0 & 2 & 1 & 2 & 0 & 0 \\  & _Trametes versicolor_ & 2 & 4 & 4 & 2 & 0 & 0 & 1 & 1 & 0 & 0 \\ \hline Russuales & _Lacarius helvus_ & 4 & 6 & 3 & 6 & 2 & 0 & 1 & 1 & 1 & 0 \\  & _Lactifluts piperatus_ & 3 & 2 & 3 & 2 & 1 & 2 & 0 & 0 & 0 & 0 \\  & _Russula integra_ & 7 & 1 & 3 & 1 & 1 & 2 & 0 & 2 & 0 & 0 \\  & _Russula lepida_ & 5 & 8 & 1 & 5 & 2 & 0 & 0 & 2 & 0 & 0 \\  & _Scutiger pes-caprae_ & 7 & 2 & 3 & 1 & 0 & 1 & 1 & 1 & 1 & 0 \\ \hline \hline \end{tabular}
\end{table} 
Table 2: Number of inhibition zones induced by mushrooms extracts on bioautograms (the higher the number of zones, the darker the background). _Ef_: _Enterococcus faecalis_, _Sa: Staphylococcus aureus_, _Se: Staphylococcus epidermidis_, _Ec: Escherichia coli_, _Pa: Pseudomonas aeruginosa_. ical structures.