## 3 Results and Discussion
### Coefficients of Antioxidant Activity Depending of the Phenolic Compounds and Type of Extract  
[PERSON] et al. [9] found that the antioxidant activities of spices (_Lippia adensis_, _Nigella sativa_, _Piper capense_, _Thymus bschimperi_, and _Trachyspernum ammi_) may vary according to the different solvents used for extraction (H\({}_{2}\)O and MeOH). Most MeOH extracts demonstrated better DPPH radical scavenging capacity than aqueous extracts. High to moderate positive correlations were observed between total polyphenols content and in vitro antioxidant assays. Furthermore, there was a strong positive correlation between total polyphenols content and antioxidant activity when using DPPH for MeOH and H\({}_{2}\)O herbal extracts, a pattern that held true for the extracts tested in the present study (Table 4). This was further confirmed by analyzing correlations among antioxidant activity, phenolic compounds, and four types of thyme/sideritis extract (Table 5). \begin{table}
\begin{tabular}{c c c c c c} \hline \hline  & & & & & \\ \hline
**Compound/AAC** & **TPC** & **TFC** & **TPAC** & **AAC-DPPH** & **AAC-FRAP** \\ \hline TPC & x & 0.106035 & 0.895424 \({}^{\star}\) & 0.148167 & 0.83135 \({}^{\star}\) \\ TFC & \(-\)0.26717 & x & 0.205463 & \(-\)0.4218 & 0.066284 \\ TPAC & 0.57718 \({}^{\star}\) & \(-\)0.93361 \({}^{\star}\) & x & 0.272149 & 0.917172 \({}^{\star}\) \\ AAC\(-\)DPPH & 0.274637 & \(-\)0.99574 \({}^{\star}\) & 0.940963 \({}^{\star}\) & x & 0.048353 \\ AAC\(-\)FRAP & 0.825931 \({}^{\star}\) & \(-\)0.55946 & 0.789627 \({}^{\star}\) & 0.591167 \({}^{\star}\) & x \\ \hline \hline \end{tabular}  
* AAC—antioxidant activity; TPC—total polyphenols content; TFC—total flavonoids content; TPAC—total phenolic acids content, \({}^{\star}\) Significant at \(p<0.05\).  
\end{table} 
Table 4: [PERSON]’s correlation coefficients of antioxidant activities and phenolic compounds content. The correlations between individual phenolic components and AAC depended on the type of solvent used in the extraction process. We found strong positive correlations between total polyphenols content and total phenolic acids content (ACT), total phenolic acids content and total flavonoids content (EtOAc, MeOH), total flavonoids content and total polyphenols content (MeOH, EtOH-H\({}_{2}\)O), antioxidant activity (DPPH) and total polyphenols content (ACT, EtOAc), antioxidant activity (DPPH) and total phenolic acids content (ACT, EtOAc), antioxidant activity (DPPH) and total flavonoids content (EtOH-H\({}_{2}\)O), antioxidant activity (FRAP) and total polyphenols content (ACT), antioxidant activity (FRAP) and total flavonoids content (EtOAc, MeOH), and antioxidant activity (FRAP) and total phenolic acids content (MeOH, EtOH-H\({}_{2}\)O). The data suggest a relationship between the content of specific phenolic compounds and antioxidant activity, but the type of extract (solvent) is a major factor in this regard. The correlation between FRAP and total polyphenols content (Folin-Ciocalteu method) can be attributed to the same single electron transfer mechanism; however, FRAP cannot detect inert phenolic compounds and thiols [18]. On the other hand, the DPPH assay provides insight into various antioxidant properties due to the different reaction mechanism used, can detect the overall antioxidant capacity of a sample, and is not specific to a single antioxidant [15; 18]. [PERSON] et al. [33] investigated the antioxidant capacity of MeOH extract from _Macaranga Napoleuca_ leaves and its fractions using DPPH, ABTS, and FRAP, as well as using the total polyphenols content and total flavonoids content methods. The highest antioxidant activity (DPPH) and ABTS was found for the EtOAc fraction, whereas the highest antioxidant activity (FRAP) was found for the butanol fraction. The butanol fraction also exhibited the highest total polyphenols content and total flavonoids content (27.51 mg GAE/g and 88.42 mg QE/g, respectively).