## 3 Results  
### Qualitative Synthesis  
As depicted in the PRISMA flowchart (Figure 1), 14 studies [17; 18; 19; 20; 21; 22; 23; 24; 25; 26; 27; 28; 29; 30] entered qualitative synthesis, involving a total of 1190 patients (Table 1). Figure 1: PRISMA flowchart. \begin{table}
\begin{tabular}{c c c c c c c c c c c c c} \hline \hline
**Author** & **Year** & **Geographic** & **Study** & **Elustography** & **Sil fitness** & **Manufacturer** & **Model** & **Probe and Frequency** & **Measurements** & **Reference** & **Histopathology** & **Imaging** \\  & & **Origin** & **Type** & **Technique** & **Measurement** & **Massurement** & **Model** & **Probe and Frequency** & **User** & **Estimation** & **Standard** & **Modality** & **Imaging** \\ \hline [PERSON] et. al. & 2009 & Europe & OP & SWE & m/s & Siemens & Acuson & Convex probe (4C1), & - & Histopathology & & US/CT/MR \\  & & & & & & & & 1-MHz & - & + Imaging & & \\ \hline [PERSON] et. al. & 2013 & Europe & OP & SE & Strain ratio & CE & LogQ D9 & & Convex probe, & - & Histopathology & Post-operative & CT/MR \\  & & & & & & & 2-S-MHz & - & + Imaging & pathology/3 bgy & & \\ \hline [PERSON] et. al. & 2014 & Asia & OP & SWE & m/s & Siemens & Acuson & Convex probe (4C1), & - & Histopathology & & Post-operative & CT/MR \\  & & & & & & & & 52000 & 1-MHz & - & + Imaging & pathology/3 bgy & & \\ \hline [PERSON] et. al. & 2014 & Europe & OP & SE & Strain ratio & Toshiba & Apollo NG & Convex probe, 35 MHz & - & Histopathology & & Post-operative & CT/MR \\  & & & & & & & & & & - Imaging & pathology/3 bgy & & \\ \hline [PERSON] et. al. & 2015 & Europe & OP & SWE & m/s & Siemens & Acuson & Convex probe (4C1), & 16 & Histopathology & Post-operative & \\  & & & & & & & & 52000 & 1-MHz & + Imaging & pathology & \\ \hline [PERSON] et. al. & 2015 & Europe & OP & SE & Strain ratio & Toshiba & Apollo NG & Convex probe & - & Histopathology & Post-operative & CT/MR \\  & & & & & & & & & 2.5-S-MHz & - & pathology & \\ \hline [PERSON] et. al. & 2015 & Asia & OP & SWE & m/s & Siemens & Acuson & Convex probe (4C1), & 10 & Histopathology & Post-operative & CT/MR \\  & & & & & & & & 52000 & 1-MHz & + Imaging & pathology & \\ \hline Incl et. al. & 2016 & Europe & OP & SE & Strain ratio & Toshiba & Apollo 500 & Convex probe, & - & Histopathology & Post-operative & - \\  & & & & & & & & 3.5-S-MHz & - & Histopathology & & \\ \hline [PERSON] et. al. & 2018 & Europe & OP & SWE & kPa & Pbilips & U22 & Convex probe (5-1), & 3 & Histopathology & Post-operative & - \\  & & & & & & & 1-S-MHz & + Imaging & pathology & \\ \hline [PERSON] et. al. & 2018 & Europe & OP & SWE & m/s & Siemens & Acuson & Convex probe (4C1), & - & Histopathology & Post-operative & - \\  & & & & & & 3000 HELL & HD), 15-MHz & + Imaging & pathology & & \\ \hline [PERSON] et. al. & 2019 & Asia & OP & SWE & kPa & Axplorer & Axplorer & Axplorer & Axplorer & Axplorer & - & Histopathology & Post-operative & - \\  & & & & & & & 1-MHz & - & + Imaging & pathology & \\ \hline [PERSON] et. al. & 2019 & America & OP & SWE & - & Siemens & Acuson & Convex probe (4C1) & 10 & Histopathology & Post-operative & CT/MR \\  & & & & & & & & 52000 & HD), 15-MHz & + Imaging & pathology & \\ \hline [PERSON] et. al. & 2020 & Asia & OR & SWE & m/s & Siemens & Acuson & Convex probe (4C1), & 5 & - & - & - \\  & & & & & & & & 52000 & 1-MHz & + Imaging & & \\ \hline [PERSON] et. al. & 2023 & Europe & OP & SWE & m/s & Pbilips & U22 & Convex probe (5-1), & 2 & Histopathology & Post-operative & US/CT/MR \\  & & & & & & & & 2.5-S-MHz & 2 & + Imaging & pathology & \\ \hline \hline \end{tabular}  
* OP = observational prospective OR = observational retrospective; SWE = shear-wave elastography; SE = strain elastography.  
\end{table} 
Table 1: Methodological study characteristics and technical features. All studies were observational, with 13/14 (93%) having a prospective design, whereas only the study by [PERSON] et al. (2018) had a retrospective design. Study size varied widely, from 15 patients with 15 masses in the study by [PERSON] et al.