# Acute Effect of a Single Functional Neurology Intervention on Muscular Trigger Point
## 1 Introduction  
Myofasical trigger points (MTrPs) are hyperiritable spots within a taut band of skeletal muscle, often presenting as palpable nodules [1]. They are a prevalent source of musculoskeletal pain, contributing to significant functional impairments and reduced quality of life [2]. Multiple therapeutic modalities have been investigated to mitigate MTrP-related pain, such as manual therapy, dry seedling, and pharmacological treatments. Nonetheless, these interventions frequently offer transient relief, underscoring the necessity for more efficacious and durable treatment strategies [3]. Including trigger point dry needing in multimodal physical therapy programs has proven effective for postoperative shoulder pain [4]. Trigger point injections with local anesthetics or corticosteroids have also shown positive outcomes [5]. Additionally, compression techniques have demonstrated efficacy in reducing pain and improving muscle function [6]. The pathophysiology of myofascal trigger points is linked to mechanoreceptors within the muscle tissue, specifically the Pacinian corpuscles [7]. These receptors, sensitive to pressure and vibration, provide feedback to the central nervous system regarding mechanical changes in the muscles. Dysfunctional or overstimulated receptors can create an abnormal feedback loop, leading to sustained muscle tension and trigger point formation [8]. Factors such as muscle overuse, trauma, or prolonged static positions can contribute to this dysfunction [9]. Myofascal trigger points are common in individuals with musculoskeletal pain conditions, with many chronic pain patients exhibiting trigger points as a primary or secondary source of pain [10; 11; 12]. The pressure pain threshold (PPT) is a crucial metric for evaluating the sensitivity and pain response of MTrPs. Measured with an algometer, the PPT is the point at which increased pressure produces pain. This measure is vital for assessing MTrP severity and monitoring therapeutic interventions' effectiveness. Studies have shown that MTrPs have a lower PPT than non-affected muscle tissues, indicating higher sensitivity and pain levels [13]. Physical therapy techniques, including manual therapy and dry needing, have been shown to increase the PPT, reducing pain and improving muscle function [14]. Reliable PPT measurement is essential for diagnosing MTrPs and evaluating treatment outcomes, ensuring effective and tailored interventions [15]. Thermography, or infrared thermography, is a valuable non-invasive imaging technique for detecting and monitoring physiological changes associated with various medical conditions. In musculoskeletal disorders, thermography visualizes temperature variations on the skin surface, corresponding to underlying vascular and metabolic activities [16]. Thermography can correlate skin temperature variations with MTrPs' vascular and metabolic activity [17]. This imaging technique provides real-time feedback on changes in blood flow and inflammation, making it a valuable tool for evaluating treatment efficacy for MTrPs, such as manual therapy and dry needing. Clinicians can better understand the physiological changes in MTrPs through thermography, aiding in precise diagnosis and treatment monitoring [10]. The prevalence and impact of myofascali trigger points on quality of life are significant, as they are a common source of musculoskeletal pain, affecting a large portion of the population and leading to chronic discomfort and disability [18]. Current therapeutic approaches vary in effectiveness, highlighting the need for empirical evidence to support innovative treatments that can provide relief and improve function. The modulation of pain in myofascali trigger points through functional neurology interventions likely involves several neurophysiological mechanisms. One key hypothesis is the regulation of central sensitization, a process in which persistent nociceptive input leads to increased excitability of neurons in the dorsal horn of the spinal cord, amplifying pain perception [19].