## 3 Results and Discussion
### Previous Studies on the Bioactivity of the Main Components of Azorean C. _japonica Leaf EO_
\begin{table}
\begin{tabular}{c c c} \hline \hline
**Component** & **Biological Activity** & **Ref.** \\ \hline \multirow{8}{*}{\(\alpha\)-Pinene} & Flavoring and Fragrance; Antiseptic and Herbicidal Properties & [53] \\  & Analgesic, Anti-AChE, Antiapoptotic, Antibacterial, Anticancer, Anticoagulant, & \\  & Anticonvulsant, Antidepressant, Antifungal, Anti-Inflammatory, Anti-_Leishmana_, & \\  & Antimalarial, Antimetastatic, Antioxidant, & \\  & Cytoprotective, Gastroprotective, Neuroprotective, & \\  & Nematicidal Properties; Cognitive Impairment and Insomnia Effects & \\  & Substrate for Chemical Reactions & [61; 62] \\  & Mosquito Repellency Effect; Anti-Quorum-Sensing Properties & [38; 59] \\ \hline \multirow{8}{*}{Sabinene} & Flavoring and Fragrance; Antiseptic and Anti-Quorum-Sensing Properties & [53; 59] \\  & Anticancer, Anti-Inflammatory, and Antioxidant Properties & [31] \\  & Antibacterial Properties (e.g., against several oral bacteria and _Helicobacter pylori_) & [24; 53] \\  & Antifungal, Anti-AChE, and Anti-BChE Properties; Skin Penetration Enhancer & [13] \\ \hline \multirow{8}{*}{Limonene} & Flavoring and Fragrance; Antiseptic, Anti-AChE, Anti-Asthmatic, Antibacterial, & \\  & Anticancer, Antidepressant, Antifungal, Anti-Inflammatory, Antimalarial, & \\  & Antimutagenic, Antiproliferative, Antispasmodic, Antiviral, and Anxolytic & [53; 54; 55] \\  & Properties; Detoxicant; Expectant; Gastroprotective and Immunomodulatory & \\  & Properties; Muscle Relaxant; Sedative & \\  & Neuropharmacological Properties; Skin Penetration Enhancer & [13; 23] \\  & Insecticidal Properties; Mosquito Repellency Effect & [38; 52] \\ \hline \multirow{8}{*}{\(\beta\)-Myrrene} & Fragrance; Analgesic, Anti-Inflammatory, and Antipsychotic Properties; Sedative; & [54] \\  & Muscle Relaxant & \\  & Antibacterial, Anticancer, Antifungal, and Antimalarial Properties & [55] \\  & Anti-AChE and Antioxidant Properties & [13] \\  & Larvicidal against _Aedes aegypti_ and _Aedes albopictus_ & [36] \\ \hline \multirow{8}{*}{\(p\)-Cymene} & Anticancer, Antifungal, and Antioxidant Properties & [13; 55] \\  & Neuroprotective Properties; Skin Penetration Enhancer & [13] \\  & Larvicidal against _A. aegypti_ and _A. albopictus_ & [36] \\ \hline \multirow{8}{*}{\(\gamma\)-Terpinene} & Anticancer, Antifungal, and Antioxidant Properties & [54] \\  & Anti-AChE, Anti-BChE, and Antioxidant Properties & [13] \\  & Larvicidal against _A. aegypti_ and _A. albopictus_ & [36] \\  & Mosquito Repellency Effect & [38] \\ \hline \multirow{8}{*}{\(\gamma\)-Terpinene} & Antispecific, Antiallergic, Anti-Asthmatic, Antibacterial (e.g., against several & \\  & oral bacteria), & [24; 53] \\  & Anti-Inflammatory, Antistivasive, and Expectorant Properties & \\  & Anticancer and Antiulcer Properties & [30; 31] \\  & Antioxidant Properties; Relaxing Effects & [54] \\  & Antifungal Properties; Skin Penetration Enhancer & [13] \\  & Mosquito Repellency Effect & [38] \\ \hline \multirow{8}{*}{Elemol} & Anticancer Properties & [54] \\  & Acaricidal against _Tetranychus urticae_ and _Tetranychus kuzzuani_ & [63] \\  & Antitermite Properties & [33] \\  & Silverfish (_Lepisma saccharina_) Repellency Effect & [34] \\ \hline \(\alpha\)-Eudesmol & Antiangiogenic, Anticancer, Antifungal, and Antimicrobial Properties & [56] \\ \hline \multirow{2}{*}{Phyllocadiene} & Anticrawal Properties & [11] \\  & AcNe\(\equiv\)acetylcholinesteraseterase; BChE\(\equiv\)butyrylcholinesteraseterase. & \\ \hline \hline \end{tabular}
\end{table} 
Table 5: Data from the literature on the bioactivity of the main components (\(\geq\)3% of total content of identified EO components) of Azorean C. _japonica_ leaf EO.