## 3 Results  
Juvenile Atlantic salmon fed the fishmeal control dietary treatment displayed normal distal intestine integrity (Figure 1A). There were no major signs of enteritis, only an indication of enteritis progression was noticed in the SBM-based diets illustrated by mild changes in distal intestine morphology, including reduced number and length of mucosal folds, enlargement of the apical zone of mucosal folds, thickening of lamina propria, and changes in abundance of goblet cells (Figure 1B-D). The removal of lipoxygenases, 11 sA4 and A5 globulins of glycinin, and oligosaccharides from SBM failed to prevent morphological changes linked to the inflammatory process. Histology scoring demonstrated statistically higher scores of goblet cells and lamina propria in the SBM treatments than the fishmeal control(Table 4). Scoring of mucosal folds was higher in the speciality SBM groups compared to the control group. Blood biochemistry was largely unaffected by the dietary treatments. Out of the sixteen parameters analyzed, only albumin and protein were statistically higher in TLP SBM than STD SBM (Table 5). Survival was high across the dietary treatments (97-100%; Table 6). No differences in production performance parameters, including CV, final weight, FCR, K, and HSI were noticed between the fishmeal control group and the SBM-based groups at day 28 and day of feeding trial. Figure 1: Light microscopic images illustrating morphological changes in the distal intestine associated with inflammatory process in Atlantic salmon fed different soybean meal types for 56 days (**(A)**—control fishmeal, **(B)**—STD SBM—standard soybean meal, **(C)**—TLP SBM – triple null soybean meal absent of seed lipoxygenases and homozygous for the rs2 allele conditioning and near absent of seed raffinose and stachyose, and **(D)**—11 sA4 null SBM—soybean meal conditioning null 11 sA4 and 11 sA5 globulins of Glycinin). \begin{table}
\begin{tabular}{c c c c c} \hline \hline
**Production** & **FM** & **STD** & **TLP** & **11 sA4 Null** & \\
**Performance** & **Control** & **SBM** & **SBM** & **SBM** & **11 sA4 Null** \\ \hline \hline
0 day & & & & \\ \hline Initial weight (g) & 37.3 \(\pm\) 0.0 & 37.4 \(\pm\) 0.0 & 37.3 \(\pm\) 0.1 & 37.3 \(\pm\) 0.0 \\ Initial CV (\%) & 12.1 \(\pm\) 0.5 & 15.7 \(\pm\) 3.4 & 11.1 \(\pm\) 0.8 & 11.5 \(\pm\) 0.5 \\ \hline
28 days & & & & \\ \hline Survival (\%) & 99 \(\pm\) 0.0 & 97 \(\pm\) 0.0 & 99 \(\pm\) 0.0 & 100 \\ CV (\%) & 12.3 \(\pm\) 1.3 & 13.0 \(\pm\) 0.5 & 12.1 \(\pm\) 0.7 & 13.1 \(\pm\) 0.9 \\ Mid weight (g) & 49.6 \(\pm\) 0.6 & 52.1 \(\pm\) 0.7 & 49.8 \(\pm\) 0.7 & 51.4 \(\pm\) 0.6 \\ FCR & 1.0 \(\pm\) 0.0 & 1.0 \(\pm\) 0.0 & 1.1 \(\pm\) 0.1 & 1.0 \(\pm\) 0.0 \\ K & 1.3 \(\pm\) 0.07 & 1.4 \(\pm\) 0.09 & 1.5 \(\pm\) 0.09 & 1.4 \(\pm\) 0.01 \\ HSI & 1.8 \(\pm\) 0.16 & 1.7 \(\pm\) 0.17 & 1.6 \(\pm\) 0.19 & 1.9 \(\pm\) 0.40 \\ \hline
56 days & & & & \\ \hline Survival (\%) & 98.5 \(\pm\) 1.5 & 97.0 \(\pm\) 1.5 & 98.5 \(\pm\) 1.5 & 100 \\ CV (\%) & 15.2 \(\pm\) 1.5 & 15.5 \(\pm\) 0.8 & 14.6 \(\pm\) 1.0 & 15.2 \(\pm\) 0.7 \\ Final weight (g) & 59.4 \(\pm\) 1.5 & 66.1 \(\pm\) 1.2 & 65.1 \(\pm\) 2.1 & 64.4 \(\pm\) 0.7 \\ FCR & 1.0 \(\pm\) 0.0 & 0.9 \(\pm\) 0.0 & 1.0 \(\pm\) 0.0 & 0.9 \(\pm\) 0.0 \\ K & 1.5 \(\pm\) 0.17 & 1.4 \(\pm\) 0.02 & 1.4 \(\pm\) 0.04 & 1.3 \(\pm\) 0.03 \\ HSI & 1.6 \(\pm\) 0.19 & 1.4 \(\pm\) 0.11 & 1.4 \(\pm\) 0.07 & 1.6 \(\pm\) 0.25 \\ \hline \hline \end{tabular}  
* CV = coefficient of variance. FCR = feed conversion ratio. K = condition factor. HSI = hepatosomatic index.  
\end{table} 
Table 6: Production performance at 28 and 56 days of juvenile Atlantic salmon fed a fishmeal control diet (FM control) and different soybean meal types-based diets (STD SBM—standard soybean meal, C—TLP SBM—triple null soybean meal absent of seed lipoxygenases and homozygous for the rs2 allele conditioning and near absent of seed raffinose and stachyose, and D—11 sA4 null SBM—soybean meal conditioning null 11 sA4 and 11 sA5 globulins of Glycinin).