## 5 Applications of Pla/Metal Biocomposites  
This study demonstrates how interfacial compuabilization plays an essential role in the development of PLA/Mg composites for use in bone regeneration [138]. To facilitate physical connections between the biopolymer matrix and the metallic filler, a synthetic amphiphilic poly-diblock polymer containing a predetermined composition was employed as an interface. (i) Modifying the composite hydrophilicity, bioactivity, and biological behavior and (ii) overcoming the PLA/Mg interface adsorption weakness were both made possible by this strategy. The last step was to conduct stem cell-based biological investigations. The findings demonstrated that the addition of the hydrophilic Mg filler to the hydrophobic PLA matrix increased the interfacial adhesion [139]. The stabilization of the interface was verified by the fact that the damping factor (tan8) decreased afterthe copolymer was added. By causing a notable increase in protein adsorption through the specific surface adaptation of the hydrophilic PEO, the latter also demonstrates the advantageous impact of the composite hydrophilicity. In addition, over eight weeks of soaking in the SBF, hydroxyapatite developed in bulk, indicating that its bioactivity is significantly enhanced with the inclusion of the diblock polymer. The ceramic has the potential to act as an inherent binding junction through the osteoregeneration process, connecting the implant to the broken bone. Composite mechanical performances, however, did show a small decline [140]. Figure 17 indicates the entire process of PLA magnesium.  
PLA-metal composites widely applied in industry for many applications. PLA-magnesium is used to fabricate anterior cruciate ligament (ACL) screws whereas PLA-zinc (plasma based) is applied in tissue engineering of bone scaffolds at the same time PLA-zinc doped with ZnO and SiC is effectively utilized in triboelectric generators which could transform mechanical energy from their surroundings into electrical energy. PLA-copper is used to fabricate and test dog bone specimens for tensile testing. PLA-bronze is utilized to 3D print items that require a metallic appearance and feel, such as jewelry, statues, artwork, and functional prototypes, and polished to make them shine like metal. PLA-brass is popular for tooling in various applications, like jigs, fixtures, and molds. PLA-titanium is well known for its strength and biocompatibility which could make PLA-based scaffolds and composite filaments for biomedical applications such as bone tissue engineering and orthopedic implants. PLA-aluminum filled filaments are used to print crafts, models. PLA-iron composites find numerous applications, including in magnetic and biological devices. PLA-silver parts could pave the way for the upcoming of low-cost, healthcare, on-demand PPE, and nosocomial devices due to their manufacturing process, their ability to interact with surfaces to prevent adhesion, and their inherent antimicrobial properties. PLA-cobalt is commonly used to create a biodegradable substrate that could work in conjunction with a colorimetric humidity indicator to detect moisture in food packaging [65]. Finally, PLA-nickel composites could create strong and corrosion-resistant parts. These parts could be used in aerospace, automotive, and medical implants. Table 2 shows the various applications of different infill metal with PLA biocomposites.  
Figure 17: Process of PLA magnesium (**_p_ \(<\) 0.01; ***_p_ \(<\) 0.001; ***_p_ \(<\) 0.0001) [140].