## 3 Results
### Influence of Other Factors  
Wilcoxon signed-rank tests were performed to determine whether pain assessment and bacterial concentrations depended on the patients' sex, but no statistically significant results were obtained. \begin{table}
\begin{tabular}{c c c c c c c c c c c} \hline \hline
**Type of Bacteria** & **Interval** & **Treatment** & **Mean** & \begin{tabular}{c} **Standard** \\ **Deviation** \\ \end{tabular} & **Median** & **Min** & **Max** & **Range** & **Q1** & **Q3** \\ \hline \multirow{4}{*}{aerobic bacteria} & first 24 h & \multicolumn{1}{c}{Nipas} & \(-0.876\) & \(0.874\) & \(-0.540\) & \(-2.98\) & \(0.67\) & \(3.65\) & \(-1.320\) & \(-0.323\) \\ \cline{2-10}  & first 24 h & \multicolumn{1}{c}{PRF} & \(-1.379\) & \(1.079\) & \(-0.975\) & \(-3.41\) & \(-0.16\) & \(3.25\) & \(-2.350\) & \(-0.447\) \\ \cline{2-10}  & second 24 h & \multicolumn{1}{c}{Nipas} & \(0.168\) & \(0.710\) & \(0.145\) & \(-1.65\) & \(2.22\) & \(3.87\) & \(-0.097\) & \(0.458\) \\ \cline{2-10}  & \multirow{2}{*}{\begin{tabular}{c} first 24 h \\ \end{tabular} } & PRF & \(0.347\) & \(0.963\) & \(0.130\) & \(-1.35\) & \(2.45\) & \(3.80\) & \(-0.007\) & \(1.008\) \\ \hline \multirow{4}{*}{anaerobic bacteria} & first 24 h & \multicolumn{1}{c}{Nipas} & \(-1.105\) & \(0.779\) & \(-0.920\) & \(-2.80\) & \(-0.11\) & \(2.69\) & \(-1.360\) & \(-0.545\) \\ \cline{2-10}  & first 24 h & \multicolumn{1}{c}{PRF} & \(-1.279\) & \(1.109\) & \(-0.680\) & \(-3.83\) & \(0.10\) & \(3.93\) & \(-1.900\) & \(-0.485\) \\ \cline{2-10}  & second 24 h & \multicolumn{1}{c}{Nipas} & \(0.492\) & \(0.795\) & \(0.730\) & \(-1.02\) & \(2.33\) & \(3.35\) & \(0.035\) & \(0.990\) \\ \cline{2-10}  & second 24 h & \multicolumn{1}{c}{PRF} & \(0.284\) & \(0.556\) & \(0.210\) & \(-0.85\) & \(2.18\) & \(3.03\) & \(0.050\) & \(0.440\) \\ \hline \multirow{4}{*}{streptococci} & first 24 h & \multicolumn{1}{c}{Nipas} & \(-1.469\) & \(0.884\) & \(-1.180\) & \(-3.60\) & \(0.34\) & \(3.94\) & \(-2.058\) & \(-0.895\) \\ \cline{2-10}  & first 24 h & \multicolumn{1}{c}{PRF} & \(-1.559\) & \(1.052\) & \(-1.330\) & \(-4.44\) & \(-0.30\) & \(4.14\) & \(-2.383\) & \(-0.735\) \\ \cline{2-10}  & second 24 h & \multicolumn{1}{c}{Nipas} & \(0.141\) & \(0.493\) & \(0.170\) & \(-1.00\) & \(0.94\) & \(1.94\) & \(-0.115\) & \(0.432\) \\ \cline{2-10}  & second 24 h & \multicolumn{1}{c}{PRF} & \(0.325\) & \(0.529\) & \(0.320\) & \(-1.01\) & \(1.54\) & \(2.55\) & \(0.085\) & \(0.767\) \\ \hline \multirow{4}{*}{enterococci} & first 24 h & \multicolumn{1}{c}{Nipas} & \(-1.597\) & \(0.932\) & \(-1.495\) & \(-3.78\) & \(0.45\) & \(4.23\) & \(-2.095\) & \(-0.995\) \\ \cline{2-10}  & first 24 h & \multicolumn{1}{c}{PRF} & \(-1.433\) & \(1.090\) & \(-1.320\) & \(-3.99\) & \(0.17\) & \(4.16\) & \(-2.065\) & \(-0.663\) \\ \cline{2-10}  & second 24 h & \multicolumn{1}{c}{Nipas} & \(1.137\) & \(0.514\) & \(1.120\) & \(-0.04\) & \(2.13\) & \(2.17\) & \(0.697\) & \(1.590\) \\ \cline{2-10}  & \multirow{2}{*}{\begin{tabular}{c} second 24 h \\ \end{tabular} } & PRF & \(0.459\) & \(0.509\) & \(0.420\) & \(-0.57\) & \(2.10\) & \(2.67\) & \(0.160\) & \(0.698\) \\ \hline \multirow{4}{*}{\begin{tabular}{c} lactic acid \\ bacilli \\ \end{tabular} } & first 24 h & \multicolumn{1}{c}{Nipas} & \(-0.306\) & \(0.575\) & \(-0.155\) & \(-2.74\) & \(0.71\) & \(3.45\) & \(-0.302\) & \(-0.103\) \\ \cline{2-10}  & first 24 h & \multicolumn{1}{c}{PRF} & \(0.175\) & \(0.411\) & \(0.210\) & \(-1.10\) & \(1.40\) & \(2.50\) & \(0.025\) & \(0.272\) \\ \cline{2-10}  & \multirow{2}{*}{\
\begin{tabular}{c} second 24 h \\ \end{tabular} } & Nipas & \(-0.218\) & \(0.256\) & \(-0.135\) & \(-1.03\) & \(0.16\) & \(1.19\) & \(-0.240\) & \(-0.100\) \\ \cline{2-10}  & \multirow{2}{*}{
\begin{tabular}{c} second 24 h \\ \end{tabular} } & PRF & \(-0.642\) & \(0.575\) & \(-0.655\) & \(-2.33\) & \(0.67\) & \(3.00\) & \(-0.848\) & \(-0.335\) \\ \hline \hline \end{tabular}
\end{table} 
Table 4: Summary statistics for changes in concentration of bacteria (kCFU/mL). Figure 11: Differences in concentrations of lactic acid bacilli.