## 3 Results
### Predicted Studies of GMDR Analysis in the Case and Control Women  
In this study, we included all the genotype data from the cases and controls and tabulated in Table 9 to show the gene-gene interaction analysis. All three thrombophilic SNPs were combined to study the gene-gene interactions, dendrograms (Figure 1) and depletion models (Figure 2). The combination of G20210A/C677T SNPs (OR-6.126 (95%CI: 1.31-28.49); \(p\) = 0.0096) and G20210A/G1691A/C677T SNPs (OR-6.270 (95%CI: 1.75-22.36); \(p\) = 0.0016) showed positive associations, while the G20210A SNP showed negative associations (OR-1.454 (95%CI: 0.72-2.91); \(p\) = 0.2903). The dendogram analysis revealed moderate association with G20210A SNP and redundancy associations between the G1691A and C677T SNPs. High, moderate and low risks were used to analyze the overall findings of this study. High risks are defined by dark boxes, lower risks by light boxes and the lack of data by blank or white boxes. The overall analysis confirmed that moderate risk exists between the thrombophilic SNPs, indicating combinations of high, low and no risk are involved in the studied population.  
\begin{table}
\begin{tabular}{c c c c c} \hline
**Genotypes** & **Infertile (\(n\) = 100)** & **Fertile (\(n\) = 100)** & **OR (95\%CI)** & \(p\)**-Value** \\ \hline GG/GG/CC genotypes & 262 (87.33\%) & 269 (89.67\%) & 1 Reference & 1 Reference \\ \hline GA/GA/CT genotypes & 31 (10.33\%) & 29 (9.67\%) & OR-1.098 (95%CI: 0.64–1.87) & 0.732 \\ \hline AA/AA/TT genotypes & 07 (2.33\%) & 02 (0.67\%) & OR-3.594 (95\%CI: 0.73–17.46) & 0.090 \\ \hline GA/GA/CT + AA/AA/TT vs. GG/GG/CC & 38 (12.67\%) & 31 (10.33\%) & OR-1.259 (95\%CI: 0.76–2.08) & 0.374 \\ \hline AA/AA/TT + GG/GG/CC vs. GA/GA/CAT & 269 (89.67\%) & 225 (75\%) & OR-1.077 (95\%CI: 0.63–1.83) & 0.785 \\ \hline GG/GC/CC + GA/GA/CAT vs. AA/AA/TT & 293 (97.67\%) & 274 (91.33\%) & OR-3.972 (95\%CI: 1.69–9.29) & 0.0006 * \\ \hline G/G/C alleles & 555 (92.5\%) & 567 (94.5\%) & 1 Reference & 1 Reference \\ \hline A/A/T alleles & 45 (7.5\%) & 33 (5.5\%) & OR-1.393 (95\%CI: 0.87–2.21) & 0.160 \\ \hline \end{tabular}
* indicates statistical significant which is \(p\) \(<\) 0.05.  
\end{table}
Table 8: Combined genotype and allele frequencies among the thrombophilic variants present in infertile and fertile women.  
\begin{table}
\begin{tabular}{l l l l l l l l l l l l l l} \hline \hline
**Model No.** & **Best Combinations** & \begin{tabular}{} \end{tabular} & \begin{tabular}{} \end{tabular} & \begin{tabular}{} \end{tabular} & \begin{tabular}{} \end{tabular} & \begin{tabular}{} \end{tabular} & \begin{tabular}{} \end{tabular} & \begin{tabular}{} \end{tabular} & \begin{tabular}{} \end{tabular} & \begin{tabular}{} \end{tabular} & \begin{tabular}{} \end{tabular} & \begin{tabular}{} \end{tabular} & \begin{tabular}{} \end{tabular} & \begin{tabular}{} \end{tabular} & \
\begin{tabular}{} \end{tabular} &
\begin{tabular}{} \end{tabular} \\ \hline
1 & G20210A & 0.5278 & 0.495 & 6/10 & 0.8 & 0.2668 & 1.118 & 1.454 (95\%C1.0 272-291) & 0.2503 & 0.6316 & 0.0667 \\
2 & G20210A + C677T & 0.5511 & 0.515 & 7/10 & 0.1222 & 0.9778 & 6.715 & 6.126 (95\%C1.1 31-28.49) & 0.0096 & 0.2136 & 0.1 \\
3 & G20210A + C1691A + C677T & 0.5700 & 0.565 & 10/10 & 0.1778 & 0.9667 & 9.944 & 6.270 (95\%C1.1 75-22.36) & 0.0016 & 0.2936 & 0.1444 \\ \hline \hline \end{tabular}
\end{table}
Table 9: Estimation of gene-gene interactions among the thumbophilic variants in infertile women.