## 1 Introduction  
Breast cancer continues to be a significant health concern globally; it represents the primary cause of cancer-linked women's mortality worldwide [1]. The complexity of breast cancer is due to many factors, such as lifestyle, genetics, hormones, and the environment. All these factors influence the development and progression of breast cancer [2]. In addition to being multifactorial, breast cancer is also distinguished by a variety of molecular subtypes, each of which has distinct molecular traits and genetic patterns that influence its clinical behaviors, treatment responses, and prognostic outcomes [3]. Impressively, progress in medical science has resulted in many effective drugs against breast cancer; for instance, anthracyclines (e.g., doxorubicin), taxanes (e.g., paclitaxel), cyclophosphamide, and platinum-based drugs (e.g., cisplatin) are used for their efficacies in the disease treatment either as adjuvants or neoadjuvants [4; 5; 6; 7]. Unfortunately, these drugs usually have their efficacies limited by linked toxicities [4; 8]. The complexity of breast cancer, its wide range of molecular subtypes, and the treatment toxicity outcomes justify the development of novel prevention and therapeutic approaches. Due to their wide range of bioactive qualities and relative lack of toxicity compared to conventional chemotherapeutic drugs, naturally occurring chemicals originating from plants have become interesting candidates for cancer research throughout time [9]. Through their antioxidant properties, bioactive substances originating from plants can have anticancer properties as a result of their ability to neutralize damaging reactive oxygen species (ROS) and reduce oxidative stress [10]. Antioxidants are essential for cellular defense [11] and the maintenance of cellular homeostasis [12]. These plant-derived antioxidants prevent oxidative damage to DNA, lipids, and proteins that promote carcinogenesis [13]. Polyphenols and flavonoids are examples of plant compounds that typically function as strong antioxidants, neutralizing ROS and protecting cellular components from oxidative damage [14]. However, polysaccharides have recently gained more attention due to their potential as antioxidants, having capacities to neutralize free radicals and potential free radicals through their side-chain glycosidic bonds and hydroxyl groups [15]. These complex molecules, which are made up of sugar units that are intricately linked together and have antioxidative potential as well, are the subject of extensive research because they have proven to slow the growth of cancer cells both in vitro and in vivo [16; 17]. In controlled laboratory settings, polysaccharides derived from various sources, including plants, fungi, and marine organisms, have demonstrated promising anticancer properties [18; 19]. P Plant polysaccharides have shown promising anticancer properties in both laboratory settings (in vitro) and inside living organisms (in vivo) [20]. These plant-based polysaccharides, such as those found in dietary staples and medicinal herbs, demonstrate a multifaceted strategy to fight cancer [21]. They have proven to be capable of inducing apoptosis in cancer cells [22], disrupting critical signaling pathways for tumor growth [23], and preventing tumor-related angiogenesis [24]. Surprisingly, despite their well-known health benefits, there is a dearth of research regarding the anticancer properties of polysaccharides derived from certain plants. _Ginkgo biloba_, _Taraxacum officinal_, _Ocimum sanctum_, _Moringa oleifera_, _Allium sativum_, and _Allium cepa_ are some examples of plants with a long history of being used for therapeutic and medicinal purposes. A well-known medicinal plant, _Ginkgo biloba_ is a source of bioactive compounds with a range of biological effects, including antiproliferative effects [25]. It is unknown, however, whether these plants' antiproliferative properties are due to their polysaccharide contents.