## 3 Results
### Anti-Inflammatory Activity  
From the literature data, it is known that BAC of species of the genus _Melampryrum_ exhibit anti-inflammatory properties [9; 13]. The study of the anti-inflammatory activity of the _M. memorosum_ herb extracts was carried out on white linear male rats (130-240 g) in accordance with the methodological recommendations of the State Centre of the Ministry of Health of Ukraine [27]. Data characterising the anti-inflammatory activity of the extracts are presented in Table 3.  
The results presented in Table 3 indicate that, in animals of the control group, the inflammatory process in the paw was accompanied by a sustained increase in its volume, which persisted until the end of the experiment. In contrast, administration of the herb  
\begin{table}
\begin{tabular}{l c c c c c c c} \hline \hline \multirow{2}{*}{**Quality Indicators**} & \multicolumn{4}{c}{**MN40**} & \multicolumn{4}{c}{**MN70**} \\  & **Batch 001** & **Batch 002** & **Batch 003** & **Batch 001** & **Batch 002** & **Batch 003** \\ \hline Identification A (description) & Meets specs & Meets specs & Meets specs & Meets specs & Meets specs & Meets specs \\ Identification B (main phenolic compounds (TLC)) & Meets specs & Meets specs & Meets specs & Meets specs & Meets specs & Meets specs \\ Quantitative content of flavonoids, \% & 0.86 & 0.85 & 0.81 & 1.01 & 0.98 & 1.05 \\ Heavy metals (not more than 0.002%) & Meets specs & Meets specs & Meets specs & Meets specs & Meets specs & Meets specs \\ Dry residue (not less than 12.0%) & 13.65 & 13.90 & 13.22 & 12.22 & 12.08 & 12.03 \\ Ethanol content, \% & 41 & 39 & 40 & 68 & 71 & 72 \\ Microbiological purity & Meets specs & Meets specs & Meets specs & Meets specs & Meets specs & Meets specs \\ \hline \hline \end{tabular}
\end{table}
Table 2: Results of determining quality indicators in the liquid extracts of _Melampryrum_ _nermost_ herb.  
\begin{table}
\begin{tabular}{l c c c c c c c} \hline \hline \multirow{2}{*}{**Group of Animals (n = 6)**} & \multirow{2}{*}{**Dose, mg/kg**} & \multicolumn{3}{c}{**Rat Paw Volume Increase, \%: \(\pm\Delta\pi\)**} & \multicolumn{3}{c}{**Inflammatory Response Suppression Index, \%**} \\  & & **In 1 h** & **In 3 h** & **In 5 h** & **In 1 h** & **In 3 h** & **In 5 h** \\ \hline Group I (AN40) & 100 & \(29.45\pm 1.57\)** & \(32.13\pm 3.33\)** & \(29.31\pm 5.92\) & 15.89 & 33.47 & 35.36 \\ Group II (MN70) & 100 & \(24.95\pm 3.12\) & \(27.88\pm 1.98\)** & \(24.38\pm 1.46\)** & \(28.82\) & 42.25 & 46.24 \\ Group II (diclofenac sodium) & 8 & \(21.29\pm 2.23\)** & 2018 & \(4.51\)** & \(17.82\pm 4.29\)** & \(39.25\) & 58.21 & 60.69 \\ Group IV (quercetin) & 5 & \(24.51\pm 2.20\) & \(29.15\pm 1.46\) & \(28.43\pm 2.3\) & 30.07 & 39.65 & 37.30 \\ Group V (control animals) & - & \(35.041\pm 4.14\) & \(48.30\pm 5.86\) & \(45.35\pm 6.62\) & - & - & - \\ \hline \hline \end{tabular} Notes: \({}^{*}\)Statistically significant difference compared to the control group (\(\geq 0.05\)); ** statistically significant difference compared to the group of animals treated with diclofenac sodium (\(\geq 0.05\)); MN40, extract obtained with 40% aqueous-ethanol solution; MN70, extract obtained with 70% aqueous-ethanol solution; \(\overline{\pi}\pm\Delta\overline{\pi}\), the results are expressed as the average mean \(\pm\) standard deviation (SD).  
\end{table}
Table 3: The effect of _Melampryrum_ nermost_ herb extracts on the development of limb oedema in rats.  
extracts led to suppression of the inflammatory response of varying intensity compared to the control group, with measurable effects observed as early as 1 h after treatment initiation.