# Analysis of Potent Odour-Active Volatile Thioids in Foods and Beverages with a Focus on Wine
## 4 Analytical Instrumentation
### Analysis by GC
4** & **Thiods** & **Year** & **Matrix** & **Form 2** & **Informational** & **Implementation** & **Multiplicity columns** & **–** & **–** & **–** & **–** \\ \hline
1 & 1 & 1995 [21] & Wine & Free & GC-CF-DE-MS & DT & \(\bullet\)**B20** (60 m x 0.22 mm, 0.25 mm) & \(-\) & \(-\) & \(-\) & \(-\) \\
2 & 5 & 1998 [22] & Wine & Free & GC-SC-IL-MSMS & QT & \(\bullet\)**B20** (60 m x 0.22 mm, 0.25 mm) & \(-\) & \(-\) & \(+\)10 & \(-\)75-00 \\
3 & 3 & 2003 [25] & Wine & Free & GC-NC-IL-MSMS & QT & \(\bullet\)**B20** (60 m x 0.25 mm, 0.5 mm) & \(-\) & \(\Leftrightarrow\) & \(<\)12 & \(-\) \\  & & & & -AED & QT & \(\bullet\)**B40** (60 m x 0.53 mm, 0.5 mm) & \(\Leftrightarrow\) & \(<\)12 & \(-\) \\  & & & & -AED & QT & \(\bullet\)**C51** (60 m x 0.32 mm, 1.2 mm) & \(\Leftrightarrow\) & & & & \\
4 & 12 & 2006 [12] & Beer & Free & GC-OC-PPP-, -FLD & ID & (CB) (25 m x 0.32 mm, 0.3 mm) & \(\Leftrightarrow\) & \(<\)67 & \(-\) & \(-\) & \(-\) \\  & & & & -EM-MS & \(\bullet\)**D5C**-S (60 m x 0.32 mm, 1.2 mm) & \(\Leftrightarrow\) & & & & & \\  & & & & -EM-MS & \(\bullet\)**D5C**-S (60 m x 0.32 mm, 1.2 mm) & \(\Leftrightarrow\) & & & & & \\  & & & & & -EM-MS & \(\bullet\)**D5C**-S (60 m x 0.32 mm, 1.2 mm) & \(\Leftrightarrow\) & & & & & \\  & & & & & & & & & & & \\
5 & 2 & 2006 [18] & Wine & Deriv. & GC-EC-N-MS & QT & \(\bullet\)**V-S**-S (20 m x 0.15 mm) & Y & \(<\) & 10-20 & \(-\) \\
6 & 2 & 2007 [60] & Wine & Free & GC-EI-MS & QT & \(\bullet\)**V-S**-S (20 m x 0.22 mm, 0.25 mm) & N & \(>\) & \(-\) & \(\approx\)100 \\
7 & 4 & 2007 [29] & Wine & Deriv. & GC-CI-MS & QT & \(\bullet\)**V-S**-S (20 m x 0.15 mm) & \(\forall\)N** & \(<\) & 10-17 & \(-\) \\
8 & 5 & 2008 [61] & Wine & Deriv. & GC-CI-MS & QT & \(\bullet\)**V-S**-S (20 m x 0.15 mm) & Y & \(<\) & 1-20 & \(\mathcal{A}\)\(\uparrow\)123 \\
9 & 2 & 2008 [61] & Wine & Free & GC-CI-MS & QT & \(\bullet\)**T**-MS (80 m x 0.25 mm, 0.25 mm) & \(\Leftrightarrow\) & \(\infty\) & \(-\) & \(-\) \\
10 & 1 & 2008 [25] & Cheese & Free & GC-OC-PPP-,-EI-MS & ID,QT & \(\bullet\)**D5C**-S (60 m x 0.25 mm, 0.5 mm) & \(-\) & \(-\) & \(-\) & \(>\)70 \\
11 & 5 & 2009 [61] & Wine & Free & GC-EI-MS & QT & \(\bullet\)**D5C**-WAT** (60 m x 0.25 mm, 0.25 mm) & \(-\) & \(\Leftrightarrow\) & 6.5\(\uparrow\)123 & \(28\)-123 \\
12 & 3 & 2009 [61] & Wine & Deriv. & GC-CI-MS & QT & \(\bullet\)**D5C**-S (60 m x 0.25 mm, 0.25 mm) & N & \(<\) & \(<\)10 & \(-\) \\
13 & 1 & 2011 [32] & Wine & Deriv. & GC-EI-MS & QT & \(\bullet\)**D5C**-S (60 m x 0.25 mm, 0.25 mm) & N & \(<\) & \(<\)2.5 & \(-\) \\
14 & 3 & 2013 [19] & Wine & Deriv. & GC-EI-MS & QT & \(\bullet\)**H**-WCN**-S (200 m x 0.25 mm) & N & \(\Leftrightarrow\) & 1.9\(\uparrow\)27 & \(94\)-112 \\  & & & & & -ALTE Class (150 m x 2.2 mm, 1.5 mm) & \(\Leftrightarrow\) & & & & \\
15 & 7 & 2013 [37] & Olive oil & Deriv. & HPLC-ES-OHMPMS & QT & \(\star\)**A**: 10 mM ammonium formate in water & Y & \(<\) & \(\approx\)13 & 79-20 \\  & & & & & & & & & & \\  & & & & & & & & & & & \\  & & & & & & & & & & & \\  & & & & & & & & & & & \\  & & & & & & & & & & & \\
16 & 1 & 2014 [43] & Beer & Deriv. & LC-ESI-MSMS & \(\bullet\)**D5C**-S (150 m x 0.2 mm, 5 mm) & & & & & \\  & & & & & & & & & & & \\ \begin{table}
\begin{tabular}{c c c c c c c c c c c c c} \hline \hline
**Entry** & **No. of** & **Unibds** & **Year** & **Matrix** & **Analyte** & **Analytical** & **Aim 3** & **Major Separation Parameters 4** & **ME 5** & **LOD * & **RSD 7 (ex)** & **Recovery 8** \\
23 & 1 & 2016 [64] & Wine & Free & GC-EI-MSMS (QQQ) & QT & \(\bullet\) ZB-1 ms (60 m x 0.25 mm, 1 s/m) & – & \(<\) & 9 & – \\
24 & 2 & 2017 [57] & Wine & Free & GC-EI-MSMS (QQ) & ID & \(\bullet\) ZB-1 ms (60 m x 0.25 mm, 1 s/m) & – & – & – & – \\
25 & 6 & 2017 [28] & Beer, & Free & GC-EI-MSMS(QQ) & QT & \(\bullet\) InertCap Pure-NXA (0.0 x 0.25 mm, 0.25 mm) & – & \(<\) & 2.8-8.4 & 74-113 \\  & & & & hops & & & & & & & & \\ \hline \hline \end{tabular}
\end{table} 
Table 2: _Cont._FPD [21], PFPD, and SCD [23; 34] are important sulfur-selective detectors [65] that are also useful when screening for volatile thiols.