## 5 Conclusions  
The goal of this study was to illustrate feasibility of the direct measurement of in vivo vocal fold collision pressures during phonation using the recently developed dual-channel ISP probe. The results successfully demonstrated this feasibility in an individual with a hemilaryngectomy, motivating ongoing data collection that is designed to aid in the development of vocal dose measures that incorporate vocal fold impact collision/stress. Even though further in vivo validation with more subjects is needed, the good agreement in this case study between the vocal fold modeling methods and the experimental results illustrates the potential of the modeling tools for both providing access to additional measures of vocal function that are difficult to obtain and advancing the understanding of the underlying control mechanisms of normal and pathological voice production. **Supplementary Materials:** The following are available online at [[https://www.mdpi.com/article/10.3390/app11167256/s1](https://www.mdpi.com/article/10.3390/app11167256/s1)]([https://www.mdpi.com/article/10.3390/app11167256/s1](https://www.mdpi.com/article/10.3390/app11167256/s1)), Video S1: Laryngeal videostroboscopy of the study participant with a right hemilaryngectomy during sustained phonation at a comfortable pitch and higher pitch. Video S2: Laryngeal high-speed videonedoscopy of vocal fold vibration (2000 frames per second) for the 100 ms phonatory segment during which the intragdial pressure sensor was in the strike zone. Video S3: Graphical user interface displaying the high-speed video of vocal fold vibration (2000 frames per second) and time-aligned signals (8000 Hz sample rate) recorded by an acoustic microphone, electroglottograph, neck-surface vibration accelerometer, intragdital pressure, and subglottal pressure. Video S4: Vocal fold edge contour displayed in the high-speed videoendoscopy data for the Hertzian contact pressure model, along with the input and output variables of the model. Signals S5-S9: The time-aligned signal data in WAV format for visualizing the signal waveforms during the 100 ms phonatory segment when vocal fold collision was detected by the intragdital pressure signal: neck-surface vibration acceleration signal (ACC; S5), electroglottography signal (EGG; S6), ISP probe intraglottal pressure sensor signal (IGP; S7) capturing vocal fold collision pressures during the phonatory closed phase and aerodynamic intragdital pressure during the phonatory open phase, acoustic microphone signal (MIC; S8), and subglottal pressure signal (SGP; S9). **Author Contributions:** Conceptualization, D.D.M. and R.E.H. ; data curation, D.D.M. ; formal analysis, D.D.M., E.J.I., R.M., and G.A.A. ; funding acquisition, D.D.M., M.Z., and R.E.H. ; investigation, D.D.M., J.B.K., S.M.Z., R.H.P., and R.E.H. ; methodology, D.D.M., J.B.K., S.M.Z., M.Z., M.D.E., S.D.P., and R.E.H. ; project administration, R.E.H. ; resources, J.B.K., S.M.Z., and R.E.H. ; software, D.D.M., E.J.I., G.A.A., and R.M. ; supervision, D.D.M. and M.Z. ; validation, D.D.M. ; visualization, D.D.M., M.Z., E.J.I., G.A.A., and R.M. ; writing--original draft preparation, D.D.M. and M.Z. ; writing--review and editing, D.D.M., M.Z., B.D.E., S.D.P., and R.E.H. All authors have read and agreed to the published version of the manuscript. **Funding:** This research was funded by the Voice Health Institute, the U.S. National Institutes of Health (NIH) National Institute on Dearfness and Other Communication Disorders (Grant P50 DC015446 awarded to R.E.H.) and the Chilean National Agency for Research and Development (ANID; BASAL Grant FB0008 awarded to M.Z. and Beca Doctorado Nacional 21190074 awarded to E.J.I.). The APC was funded by the U.S. National Institutes of Health (NIH) National Institute on Dearfness and Other Communication Disorders (Grant P50 DC015446 awarded to R.E.H.). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.