## 3 Results
\begin{table}
\begin{tabular}{c c c c c} \hline \hline
**Characteristics** & **All Patients (n = 47)** & **Survivors (n = 27)** & **Non-Survivors (n = 20)** & \(p\)**-Values** \\ \hline FMD (\%) & 8.2 \(\pm\) 3.6 & 9.71 \(\pm\) 3.53 & 6.13 \(\pm\) 2.62 & \textless{}0.001 \\ Mean C-IMT (mm) & 0.69 \(\pm\) 0.15 & 0.68 \(\pm\) 0.13 & 0.71 \(\pm\) 0.17 & 0.48 \\ APAO (cm) & 1.58 \(\pm\) 0.27 & 1.61 \(\pm\) 0.29 & 1.54 \(\pm\) 0.23 & 0.45 \\ LV EDD (mm) & 43.0 \(\pm\) 8.9 & 40.76 \(\pm\) 3.71 & 46.07 \(\pm\) 12.56 & 0.043 \\ LVESD (mm) & 28.2 \(\pm\) 5.0 & 26.30 \(\pm\) 4.03 & 30.79 \(\pm\) 5.02 & 0.0014 \\ IVS (mm) & 11.1 \(\pm\) 1.8 & 10.9 \(\pm\) 1.7 & 11.3 \(\pm\) 1.8 & 0.42 \\ LA APD (mm) & 36.7 \(\pm\) 5.2 & 36.0 \(\pm\) 5.8 & 37.7 \(\pm\) 4.3 & 0.30 \\ AoR (mm) & 29.5 \(\pm\) 3.2 & 28.6 \(\pm\) 3.0 & 30.7 \(\pm\) 3.2 & 0.03 \\ LVEF (\%) & 59.5 \(\pm\) 3.9 & 60.8 \(\pm\) 3.0 & 57.8 \(\pm\) 4.4 & 0.009 \\ Left E (cm/s) & 67.96 \(\pm\) 22.29 & 61.41 \(\pm\) 13.68 & 76.8 \(\pm\) 28.36 & 0.02 \\ Left A (cm/s) & 76.04 \(\pm\) 20.99 & 79.98 \(\pm\) 18.98 & 70.71 \(\pm\) 22.84 & 0.14 \\ Left E/A ratio & 1.00 \(\pm\) 0.62 & 0.79 \(\pm\) 0.19 & 1.29 \(\pm\) 0.85 & 0.0048 \\ Left e\({}^{\prime}\) (cm/s) & 7.39 \(\pm\) 2.32 & 7.24 \(\pm\) 2.75 & 7.60 \(\pm\) 1.64 & 0.60 \\ Left a\({}^{\prime}\) (cm/s) & 9.37 \(\pm\) 3.14 & 9.37 \(\pm\) 2.41 & 9.38 \(\pm\) 3.98 & 0.99 \\ Left s\({}^{\prime}\) (cm/s) & 7.11 \(\pm\) 1.75 & 7.25 \(\pm\) 1.68 & 6.92 \(\pm\) 1.87 & 0.53 \\ Left IVRT (ms) & 71.49 \(\pm\) 19.75 & 71.48 \(\pm\) 20.13 & 71.50 \(\pm\) 10.74 & 0.99 \\ Left ET(ms) & 282.77 \(\pm\) 39.31 & 284.07 \(\pm\) 34.67 & 281.00 \(\pm\) 45.73 & 0.79 \\ Left IVCT (ms) & 60.32 \(\pm\) 17.52 & 57.78 \(\pm\) 16.25 & 63.75 \(\pm\) 18.98 & 0.25 \\ Left Tei index & 0.47 \(\pm\) 0.12 & 0.46 \(\pm\) 0.12 & 0.49 \(\pm\) 0.13 & 0.45 \\ Left E/e\({}^{\prime}\) ratio & 10.05 \(\pm\) 4.73 & 9.55 \(\pm\) 4.11 & 10.72 \(\pm\) 5.50 & 0.41 \\ TAPSE (mm) & 22.7 \(\pm\) 4.1 & 23.1 \(\pm\) 4.1 & 22.3 \(\pm\) 4.1 & 0.52 \\ Right E (cm/s) & 50.26 \(\pm\) 10.73 & 50.10 \(\pm\) 10.21 & 50.47 \(\pm\) 11.66 & 0.91 \\ Right A (cm/s) & 51.40 \(\pm\) 14.33 & 52.60 \(\pm\) 12.37 & 49.78 \(\pm\) 16.83 & 0.51 \\ Right E/A ratio & 1.04 \(\pm\) 0.36 & 0.99 \(\pm\) 0.27 & 1.12 \(\pm\) 0.45 & 0.23 \\ Right e\({}^{\prime}\) (cm/s) & 11.56 \(\pm\) 3.71 & 10.98 \(\pm\) 2.90 & 12.36 \(\pm\) 4.55 & 0.21 \\ Right a\({}^{\prime}\) (cm/s) & 15.96 \(\pm\) 5.00 & 16.25 \(\pm\) 4.50 & 15.57 \(\pm\) 5.69 & 0.65 \\ Right s\({}^{\prime}\) (cm/s) & 12.91 \(\pm\) 3.23 & 12.94 \(\pm\) 3.13 & 12.88 \(\pm\) 3.45 & 0.95 \\ Right IVRT (ms) & 63.08 \(\pm\) 18.75 & 62.59 \(\pm\) 21.05 & 63.75 \(\pm\) 15.63 & 0.84 \\ Right ET (ms) & 284.04 \(\pm\) 46.28 & 281.11 ROC curve analysis was used in order to identify the cut-offs of the echocardiographic and vascular parameters that were able to predict mortality. Table 3 gathers the main findings from the analysis, where the baseline LVEF \(\leq 57\%\) and baseline FMD value \(\leq 5.8\%\) represent the significant cut-offs retrieved from the analysis. Figure 1: Survival curves for all-cause mortality according to the vascular and echocardiographic parameters dichotomized by their optimal cut-off. FMD: flow-mediated vasodilitation of the branchial artery; LVEF: left ventricle ejection fraction; TAPSE: tricuspid annular plane systolic excursion. Nevertheless, in the multivariate Cox regression analysis, only the LVEF, FMD, and E/A ratio demonstrated that they acted as independent predictors of all-cause mortality in patients suffering from gynecological cancers (Table 4).