## 4 Conclusions
However, effective adaptation requires addressing cultural nuances, such as communication styles, interaction preferences, and motivational techniques, alongside careful translation to ensure cultural relevance. Despite these challenges, PANDORA's robust framework and Dialogflow's extensive language support provide a solid foundation for efficient customization across diverse settings. Beyond promoting exercise adherence, PANDORA has the potential to provide emotional support, reduce isolation, and enhance the overall quality of life for People with Parkinson's Disease (PwPD). As a scalable and low-cost solution, it can complement traditional healthcare by offering remote support, particularly valuable for patients in underserved areas. Its design and motivational framework, grounded in Self-Determination Theory, further extend its applicability to broader healthcare contexts. By fostering autonomy, competence, and relatedness, PANDORA could be adapted to support patients managing other chronic or neurodegenerative conditions, such as Fibromyalgiagia, Amyotrophic Lateral Sclerosis (ALS), or stroke recovery, which similarly require sustained engagement with therapeutic routines and benefit from tailored motivational support. Incorporating features such as biometric monitoring and personalized interventions, PANDORA could integrate seamlessly with existing healthcare platforms to enable more holistic and effective care. This adaptability positions it not only as an innovative solution for enhancing patient engagement and well-being in Parkinson's management, but also as a versatile tool for supporting multidisciplinary approaches across a range of chronic conditions. Conceptualization, P.M. ([PERSON]), R.N.M. and P.M. ([PERSON]); methodology, P.M. ([PERSON]), R.N.M., P.M. ([PERSON]) and P.A.S. ; software, P.M. ([PERSON]); validation, P.M., R.N.M., P.M. ([PERSON]), B.A. and C.M.P. ; formal analysis, P.M. ([PERSON]), P.A.S. and R.N.M. ; investigation, P.M. ([PERSON]), R.N.M., P.M. ([PERSON]), P.A.S., B.A. and C.M.P. ; resources, P.M. ([PERSON]), R.N.M. and C.M.P. ; data curation, P.M. ([PERSON]) and R.N.M. ; writing--original draft preparation, P.M. ([PERSON]) and R.N.M. ; writing--review and editing, P.M. ([PERSON]), R.N.M., P.A.S., B.A. and C.M.P. ; supervision, P.M. ([PERSON]) and R.N.M. ; project administration, R.N.M. and C.M.P. ; funding acquisition, P.M. ([PERSON]), R.N.M. and C.M.P. All authors have read and agreed to the published version of the manuscript. This research was funded by Instituto Politecnico de Setibal under the reference MoveONParkinson. The study was conducted according to the guidelines of the Declaration of Helsinki. Ethical review and approval have been obtained consulting ethics committee \"Comissao Especializada de etica para a Investigacao do Instituto Politecnico de Setibal\" (approval code: 76A/CC/2021; approval date: 7 July 2021). Informed Consent Statement: Informed consent was obtained from all subjects involved in the research and studies. The original contributions presented in this study are included in the article. Further inquiries can be directed to the corresponding author. The authors acknowledge the individuals with Parkinson's Disease, their caregivers, and healthcare professionals who generously participated in this study. Special thanks go to the Portuguese Association for People with Parkinson's Disease (APDFk) and Saudis for their support. The authors assume full responsibility for the research, content, analysis and conclusions presented in this work. The authors declare no conflicts of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results.