## 1 Introduction
Figure 2: Diagram of the biotextronics insert: 4—heating insert (A—insert with applied essential oils; B and D—electrical insulating layers; C—system heating element); 2—textile signal line; and 3—battery [1]. maintaining the appropriate temperature during therapy. The textronics insert together with the replaceable insert (Figure 1(5) and Figure 2(A)) with applied essential oils form the biotextronics insert. Power to the biotextronics system can be supplied via a 5 V lithium-polymer battery [1]. The essential oil is applied on the insert with an agar film and cellulose or microcrystalline cellulose as carriers. Cellulose is the most abundant biopolymer with extensive sources in nature [14; 15]. It is a natural long-chain polymer that plays an important role in the human food cycle, indirectly. This polymer has versatile uses in many industries such as veterinary foods, wood and paper, fibers and clothes, and the cosmetic and pharmaceutical industries as an excipient. Pure cellulose is available in different forms in the market with very different mechanical and pharmaceutical properties. The difference between various forms of cellulose is related to the shape, size, and degree of crystallinity of their particles (fibrous or agglomerated). Microcrystalline cellulose is the most known cellulose, which is extensively used in pharmaceutical industries. Microcrystalline cellulose grades are multifunctional pharmaceutical excipients which can be used as compressibility enhancers, binders in wet and dry granulation processes, thickeners and viscosity builders in liquid dosage forms, and free-flowing agents in solid dosage forms. The mechanical properties of microcrystalline cellulose grades are greatly influenced by their particle size and degree of crystallization [16]. In the previous research, there was an investigation of five essential oils from _Matricaria chamonilla_ L., _Salvia officinalis_ L., _Salvia lawandulaefolia_ [PERSON], and _Juniperus communis_ L. _Thymus vulgaris_ L., which were concluded to have anti-inflammatory and antibacterial activity. EOs were investigated to examine their antimicrobial activity against bacteria that cause lower urinary tract inflammations: _Escherichia coli_, _Staphylococcus epidermidis_, _Pseudomonas aeruginosa_, and _Enterococcus faecalis_. Chamomile essential oil was chosen to be used in a model outer insert with antibacterial activity [1]. Chamomile essential oil was obtained during classic steam distillation, lasting from 7 to 13 h. The repeated distillation allowed the oil extraction efficiency to be increased by 30%. The efficiency of the process was low and amounted to approximately 0.20-0.63%. The EO was characterized by a light blue color, which was caused by the terpenoid-chamazulene [17]. The main ingredients of chamomile EO include \(\alpha\)-bisabolol (1-60%), chamazulene (2-25%), en-in-dicycloether (6%), \(\alpha\)-bisabolol A oxide (2-60%), n-octanal (6.0%), \(\alpha\)-bisabolol B oxide (3-50%), \(\alpha\)-bisabolone A oxide (0.4-12%), 1.8-cineole (3.9%), (E)-\(\beta\)-farnesene (5-40%), \(\alpha\)-terpineol (approx. 3%), germacrene D (3%), (E)-(Z)-spiroethers (4-18%), and polyacetylene derivatives [18; 19; 20]. It is \(\alpha\)-bisabolol which is mainly responsible for the antibacterial properties; however, chamazulene also has antimicrobial activity against Gram-positive bacteria [21]. \(\alpha\)-Bisabolol, one of the main ingredients of chamomile oil, has a relaxing effect on intestinal smooth muscles. It also has anti-inflammatory, antibacterial, antifungal, and antipyretic properties, and prevents the formation of ulcers. Chamazulene, produced in the oil during distillation, has anti-inflammatory, antiallergic, and antispasmodic properties. Other components of the oil have similar properties, as well as carminative properties due to apigenin, flavonoids, and luteolin. Apigenin also binds to GABA receptors (\(\gamma\)-aminobutyric acid-binding membrane receptors) and has a mild sedative effect.