# Effects of a Short-Term Supervised Exercise Program in Women with Breast Cancer
## 2 Materials and Methods
### Participants  
Thirty women with breast cancer participated in the study (Table 1). All of them met the inclusion criteria, which were as follows: (1) aged between 18 and 70 years, (2) diagnosed with oncological stage I, II, or III, who were currently receiving or had received chemotherapy, radiotherapy, or hormonal therapy in the last year, (3) scoring between 1 and 3 on the Eastern Cooperative Oncology Group (ECOG) scale, (4) having completed treatment and within one year of completion (surgery, chemotherapy, radiotherapy, or hormonal treatments: aromatase inhibitors, tamoxifenfen), (5) scoring between 1 and 3 on the Eastern Cooperative Oncology Group (ECOG) scale, (6) absence of musculoskeletal pathology, (7) absence of cardiopulmonary pathology limiting physical activity.  
Additionally, none met any of the exclusion criteria, which were: (1) refusal to sign informed consent, (2) inability to read, understand, and complete questionnaires, (3) inability to read and understand an explanatory leaflet, (4) inability to understand and follow verbal instructions (e.g., illiteracy, dementia, or blindness), (5) significant neurological alterations affecting balance, coordination, or ataxia, (6) sports activity of moderate intensity greater than 120 min/week and/or previous experience in strength work, (7) symptomatic anemia, (8) fecal incontinence, (9) digestive stoma, (10) decompensated heart disease, (11) heart  
\begin{table}
\begin{tabular}{c c c} \hline \hline  & **Mean \(\pm\) SD** & **(95\% CI) Min–Max** \\ \hline Age (years) & 55.9 \(\pm\) 6.3 & (45.6 to 62.7) 36–67 \\ Weight (kg) & 72.9 \(\pm\) 10.5 & (68.1 to 77.4) 55–69.4 \\ Height (cm) & 160.8 \(\pm\) 6.6 & (151.4 to 166.4) 151–181 \\ BMI & 28.2 \(\pm\) 3.9 & (22.6 to 29.2) 21.0–30.0 \\ \hline
**TREATMENT** & \(\mathbf{n}\) & **(\%)** \\ Chemotherapy & 26 & (86.6) \\ Radiotherapy & 29 & (96.6) \\ Hormonal therapy & 22 & (73.3) \\ Completed treatment & 19 & (63.3) \\ \hline \hline \end{tabular} Abbreviations: SD, standard deviation; CI, confidence interval.  
\end{table}
Table 1: Descriptive data measurements for anthropometric variables, age, and BMI.  
Figure 1: Study design. 6 MWT = 6 min walking test; 30s-stst = 30 s sit to stand test; EORTC QLQ-C30 = European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C-30; FACIT-F = Functional Assessment of Chronic Illness Therapy—Fatigue.  
failure, (12) cardiotoxicity with hemodynamic repercussions, (13) uncontrolled arrhythmias, and (14) uncontrolled hypertension.  
The study design was approved by the ethics committee of the Hospital Universitario Infanta Leonor and the Virgen de la Torre Hospital (internal code 012-23) and conducted in accordance with the Helsinki Declaration for human studies [43]. Data confidentiality of the participants was ensured in compliance with Organic Law 3/2018 of 5 December on Data Protection and Guarantee of Digital Rights. The study population was recruited by the oncology service of the hospital, which informed potential participants about the study and provided them with an information sheet and informed consent form (Figure 2). Subsequently, those patients who decided to participate attended an appointment where any doubts or questions were addressed, they signed the informed consent form in duplicate, and baseline measurements were taken. In the week prior to the start of the study, a training session was organized with all participants, where they were instructed on the prescribed exercise protocol, follow-up, frequency of controls, etc., and provided with a dossier containing all the information on the applied therapeutic exercise protocol. All participants were measured in the week before beginning the study and again in the week after completing the intervention.