###### Abstract  
The objective of this study was to devise effective safety management systems for enclosed living modified organism (LMO) fields regulated by the Ministry of Environment (MOE), achieved through an assessment of the impact of LM crops on the surrounding flora. A combination of conventional survey methods and cutting-edge drone-based monitoring systems was employed, with a keen focus on their efficacy. Our investigation spans three distinct zones (forest, non-forest, and enclosed field), involving vegetation surveys, biodiversity index analyses, and drone-powered aerial observations to study topographical shifts. Over time, wild plants adjacent to the enclosed LMO field exhibited stability in terms of species composition. Nevertheless, disparities in growth patterns emerged across various areas. Predominantly, herbs thrived in enclosed and non-forest areas, while trees and shrubs flourished in forested regions. Annual plants predominantly populated the non-forest regions, whereas perennials dominated the forested areas. To this end, drones captured aerial photographs of a 31.65-hectare expanse with 40% coverage overlap, furnishing a real-time vegetation map that transcends the capacities of conventional methods. By combining vegetation surveys, drone-generated vegetation mapping, and dynamic monitoring of topographical changes, our research endeavors to facilitate the formulation of a robust safety management framework for LMO confined fields overseen by the MOE. This holistic approach aspires to prevent ecosystem contamination and establish a resilient, enduring system that averts LMO leakage, thereby safeguarding the environment. confined field; living modified organism; risk assessment; vegetation survey; safety management; drone-based mapping +
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release, and safety assessment [5]. LMO confined field management demands multifaceted actions, including risk evaluation, leakage monitoring, contingency planning, and the formulation of standard operating procedures [6]. Monitoring environmental indicators is a pivotal facet of managing regions frequently planted with LMOs. Specifically, LMOs spread and escape into the surrounding environment [7]. Since LM crops can disseminate through pollen and seeds, meticulously evaluating their impact on neighboring plant communities is imperative [8]. The surveillance of vegetation adjacent to LMO confined fields provides vital insights into the real-world spread and persistence of LMOs [9]. In Korea, confined field experiments mandate investigating the distribution of indigenous or closely related wild species capable of hybridizing with tested LM crops. If they exist within the hybridization range, their removal becomes essential. Additionally, safety measures must be established to preclude transgene transfer or leakage from LM crops within the confined field. Parallelly, effective safety management of LMO confined fields demands LMO leakage detection and scrutinizing changes within the surrounding flora and vegetation. Utilizing standardized biodiversity indices, like the Shannon-Weaver and Simpson diversity indices, enables a quantitative assessment of LMO impacts on plant biodiversity [10]. Modern times have witnessed the ascendancy of drone-based aerial photography as a potent tool in LMO confined field management [11]. Drone imagery analysis, which surpasses the conventional resolution of satellite images, improves agricultural productivity as well as environmental conservation by supporting crop yield prediction and invasive species detection [12; 13; 14; 15]. In addition, drones also serve as effective tools for animal monitoring and optimization of livestock management systems, resulting in cost reductions [16; 17; 18; 19; 20; 21]. Therefore, this innovative technology can solve immediate issues such as environmental preservation, marine waste cleaning, or forest fire monitoring [22; 23].