## 3 Perspectives and Outcomes of the Presented RHMS with a Focus on Diet-Related Approaches
### Schizophrenia, Dietary Habits, and Physical Health  
#### 3.2.1 Link between Schizophrenia, Dietary Habits, and Physical Health  
Because of the complex interplay between medication and lifestyle decisions, people with schizophrenia tend to have an increased chance of developing metabolic syndrome [140]. Although the adverse effects of antipsychotic medications on obesity and problems with the metabolism of carbohydrates in patients with schizophrenia are well established, weight increase is seen even before the start of medication, indicating the important role that lifestyle decisions play. Schizophrenia patients, in comparison with the general population, exhibit inadequate nutritional choices: high daily energy consumption, a substantial intake of animal fats,  
\begin{table}
\begin{tabular}{c c c c} \hline \hline
**Targeted Functionalities of the** & & **Brief Presentation** & **Characteristics and Requirements** \\ \hline \multirow{4}{*}{Sign and symptom evaluation} & - & Includes easy-to-fill sign and symptom & - & Required smart device: \\  & & questionnaires and body temperature & & Withings Thermo \\  & - & monitoring tool & - & Needs patient/caregiver cooperation for \\  & - & Triggers alerts for acute sign and & - & symptom reporting \\  & - & symptom management & - & \\  & - & Triggers alerts in case of rapid weight gain in & - & Crucial for improvement in \\  & - & consecutive days & - & nutritional status \\ \multirow{4}{*}{Ascites management} & - & Enables interventions like a reduction in salt intake, & - & Reduces the risk of SBP and HRS, and \\  & & increase in diuretic dose, and monitors weight loss & - & early intervention may eliminate the \\  & & patterns to determine the need for & - & need for paracents \\  & & additional interventions & - & Required smart device: \\  & & - & Crucial for early intervention and \\  & - & Includes sign and symptom-based evaluation and a & - & prevention of HE \\  & - & validated neurophysiologic screening test for & - & Intricated with age-related cognitive \\  & - & detection of overt HE & - & impairment, alcohol use, certain \\  & - & Triggers immediate intervention (either dietary & medications, or sleep apnoea \\  & - & intervention, BCA supplementation or lactulose & (daytime sleepiness) \\  & & administration) & - & Needs patient/caregiver cooperation for \\  & & symptom reporting & - & Crucial for beta-blocker titration and \\  & - & Enables heart rate monitoring and one-lead ECG & early detection of complications \\  & - & with feature of AF detection & (hypotension, bradycardia \\  & - & Includes blood pressure monitor & - & or arrhythmia) \\  & - & Includes blood pressure monitor & - & Required smart devices: Withings BPM \\  & - & Integrated noninvasive glucose monitoring & - & Core, Withings Move ECG \\  & - & devices and personalized alarm features for & - & Crucial for diabetic patients \\ Continuous glucose monitoring * & - & prompt intervention & - & Advanced LC predisposes to \\  & - & Enables personalized dietary and medical & - & hypoglycaemia and potentially \\  & - & interventions for patients with T2 DM & - & fatal complications \\  & - & Enables sleep pattern monitoring and interpretation & - & Offers important data about sleep \\ Sleep monitoring & - & and sleep apnoea detection & - & patterns and tracks sleep-wake rhythm \\  & - & Offers the possibility for personalized intervention & - & disturbances as a potential indicator of \\  & - & Trades medication adherence, adverse effects, or & early HE \\ Medication adherence monitoring & - & Neighs are not and a lower intake of vegetable fats. This dietary pattern is linked to higher inflammatory markers, potentially contributing to metabolic syndrome development. Global patterns indicate that countries with a higher total intake of dietary fat, particularly saturated fat from land animals, have a higher prevalence of schizophrenia [141].