# Magnetic Nanoparticles: Synthesis, Characterization, and Their Use in Biomedical Field
###### Abstract  
In recent years, the use of magnetic nanoparticles (MNPs) in biomedical applications has gained more and more attention. Their unusual properties make them ideal candidates for the advancement of diagnosis, therapy, and imaging applications. This review addresses the use of MNPs in the field of biomedicine encompassing their synthesis, biofunctionalization, and unique physicochemical properties that make them ideal candidates for such applications. The synthesis of magnetic nanoparticles involves a range of techniques that allow for control over particle size, shape, and surface modifications. The most commonly used synthesis techniques that play a crucial role in tailoring the magnetic properties of nanoparticles are summarized in this review. Nevertheless, the main characterization techniques that can be employed after a successful synthesis procedure are also included together with a short description of their biomedical applications. As the field of magnetic nanoparticles in biomedical applications is rapidly evolving, this review aims to serve as a valuable resource, especially for young researchers and medical professionals, offering basic but very useful insights into recent advancements and future prospects in this highly interdisciplinary research topic.  
magnetic nanoparticles; biomedical applications; nanomaterials +
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corresponding oxides, while the coating shell is responsible for limiting the interaction of the NPs with the medium, thus preserving their structure and properties. The high surface area of MNPs allows for easy surface modifications, making them versatile for various applications. In view of their use in biomedical applications, the coating plays a crucial role in providing the enhanced biocompatibility of MNPs, without affecting their unique magnetic properties. However, the characterization of such nanostructures is of major importance when it comes to biomedical applications. In this regard, many different techniques were developed that can be used to evaluate the physical and chemical properties of MNPs.  
Since MNPs simultaneously possess magnetic properties and experience confinement effects in all three dimensions, a wider range of novel properties that can be harnessed for practical biomedical applications and the exploration of fundamental scientific phenomena can be envisaged.  
This paper explores the remarkable properties of MNPs, offering insights into their synthesis and characterization methodologies alongside their applications in the biomedical field. In biomedicine, MNPs show promise for targeted drug delivery, magnetic hyperthermia for cancer treatment, and improved contrast in magnetic resonance imaging. Furthermore, MNPs provide a platform for interdisciplinary research with broad implications for practical applications and scientific exploration. The comprehensive and complete review of relevant aspects related to the synthesis, characterization, and potential applications of MNPs is reflected in the abundance of high-quality bibliographic resources within this scientific work. The novelty lies in its friendly approach to the subject matter and the clear delivery of concepts. This article has the potential to introduce even the most inexperienced readers to the captivating world of magnetic nanoparticles.