###### Abstract  
Background:This is the first ethnobotanical study focused on medicinal plants traditionally recommended by traditional healers (THs) of Eastern Morocco. In this work, we documented the medicinal plants recommended by THs and highlighted the value and importance of medicinal plants recommended by specialist healers. **Methods:** A quali-quantitative ethnobotanical method has been performed, snowball sampling and structured interviews were used to evaluate the traditional plant knowledge by traditional healers in the study area. Species identification was performed and verified from the African Plant Database and Plant List. Two Relative Cultural Importance indices were used for this analysis \"Informat Consensus Factor (ICF) and Frequency of Citation (FC)\". Results: A total of 135 plants were inventoried in our surveys. These species belong to 64 families and were reported to be used to treat 23 different categories of ailments. The botanical profile of the plants listed is dominated by LAMIACEAE's Family with 12 species, followed by FABACEAE (11 species) and ASTERACEAE (10 species). In the category of the digestive system, nutrition problems and nervous system problems seem to be the predominant diseases treated. The Informat Consensus Factor (ICF) results indicated that cancer and gastrointestinal disorders had a higher concordance among informants (ICF = 0.60 and 0.58 respectively). **Conclusion:** Our results, showed that the Traditional healers, in Eastern Morocco, hold impressive knowledge related to the use of medicinal plants. This observation is reflected in the high number of medicinal plants recommended for the medication of the population. Furthermore, the consistency of healers in this area of study is justified by the ICF values. Keywords:indigenous knowledge; traditional healers; medicinal plant; Informat Consensus Factor +
Footnote †: journal: _Sciences_  
pharmacopeia was further developed and enriched by other knowledge brought in by various ethnic groups that migrated to Morocco from many areas, including the Arabs from the Middle East, the Andalusians, Jews from Europe, and the Blacks from Sudan, Senegal, and Niger. According to several distinguished authors such as [PERSON] (1877-1883) [1], who synthesized all medicinal drugs used by the Arabs up to the 13 th century. Different works of literature confirm the progression of the knowledge of the Arab civilization through North Africa and the South of Spain [1,2]. So, Moroccan folk medicine is composite and complex. It is based on Arab-Islamic medicine but also hosts the elements of Greek medicine, Indian, Chinese, European, and black Africa since Morocco has been a major stopover and the crossroads of goods and cultures in Southern Europe, the Middle East, Central Asia, and Black Africa. Currently, in Morocco, several medical systems co-exist and give rise to a plural offer of therapeutic resources. Moroccan folk medicine in Morocco is a multidisciplinary and multispectral field. According to [PERSON]. [3] and [PERSON]. [4], Moroccan traditional healers are classed into three groups  
* The _fuqaha_ (singular: _faflt_), _tolba_ (singular: _taleb_) or _tobba_ (singular: _tabtb_), and the healers of all kinds (_kuvway_ or cautery installer, _hajjam_ or barber phlebotomist, _jabbar_ or bonestter, _mul ssnan_ or tooth puller, _qabla_ or traditional birth attendant... )
* The apothecaries who divide themselves into two very distinct guilds _'attarin_ (singular: _'atftar_) and the _'asSabin_ (singular: _'asSab_). _'atftarin_ represents what could be called the apotheary grocers, traders of spices, aromatics, and medicinal drugs expensive and imported from distant lands. The _'asSabin_ are the herbalists proper or merchants of medicinal and aromatic plants whose range, more diverse, has a large number of medicinal and magical drugs (roots, dried plants, seeds, bark, minerals, animal products) or confections, crammed together with various ingredients used in magic.