# The Central Dogma of Information
## 7 Comparison between Info-Autopoiesis and Genomic Flow of Information
The essence of both the central dogma of molecular biology and the central dogma of information lies in a comparing Figure 6b to Figure 8b. In each instance we need to recognize that there are three unknown transfers that can never occur: For the prokaryotic cell: Protein from Protein, RNA Synthesis and DNA Synthesis; for the human being: Syntactic Information from Syntactic Information, Semantic Information from Syntactic Information, Info-autopoiesis from Syntactic Information. It is a time-tested fact that the three unknown transfers strictly hold for the central dogma of molecular biology. As to the three unknown transfers for the central dogma of information a cursory review shows that they hold as well, after gaining a clear understanding of info-autopoiesis. A cautionary note is that if only one instance is found that contradicts this, the central dogma of information falls apart. Let us briefly examine each of the three unknown transfers associated with the central dogma of information to at least gain some understanding of their validity:  
Syntactic Information from Syntactic Information--let us consider a written text in digital form as an example of syntactic information. We might then ask, can this piece of written text at on its own to create a different piece of written text? The same thing can be asked of any human artifact, whatever its nature and the result is that it is as inactive as when it was created. Some might wonder whether artificial intelligence (AI) might fall outside of this sphere of artifacts since much has been done in the field of AI. AI relies mainly on computations performed by a computer that depend on software. The software and computer used are syntactic human products. They can only act because of human actions. Neither can act on its own. Whether a cursory or a deep dive is carried out to explore this issue, the result will be the same: it is not possible for syntactic information to generate other syntactic information, except by the action of a human. Semantic Information from Syntactic Information--The generation of semantic information from syntactic information is another impossibility. Looking again at the example of generated written text, what we find is that when another human looks at the written text, she will need to interpret it to generate semantic information. Additionally, each different individual that looks at it might find different semantic meaning. This is the lesson learned from [PERSON] (1948) and the mathematical theory of communication. Info-autopoiesis from Syntactic Information--This is another instance where once syntactic information is generated the only access that humans have to it is through our senses. Using our sensory organs, we gain cognition of it so that we can interpret the syntactic information in front of us and give it meaning through info-autopoiesis. The result is that we can never gain access to syntactic information directly by info-autopoiesis. In short, this comparison of the central dogma of molecular biology and the central dogma of information shows many common features. The main common feature is that both a prokaryotic cell and a human are living organisms-in-their-environment that must satisfy their physiological and/or relational needs to prosper. The cell and the human exhibit an ability to process 'cell signals' and'sensory signals,' respectively. In the case of the cell, DNA takes care of biochemical processing these signals (transcription) in the nucleus to produce semantic information in the form of mRNA, which through translation outside the nucleus produces syntactic information in the form of proteins. Or 'Once information has got into a protein it can't get out again'. In the case of a human, sensory signals are info-autopoietically processed in the central nervous system to endogenously produce semantic information which on externalization becomes exogeneous syntactic information. Or similarly, 'once semantic information has got into syntactic information it can't get out again'.