## 3 Results
\begin{table}
\begin{tabular}{c c c c} \hline \hline
**Parameter** & **PRP Group** & **Control Group** & **\(p\)-Value** \\ \hline \multicolumn{4}{c}{WOMAC Total mean (\(\pm\)SD)} \\ Preoperative & 1354.2 (\(\pm\)627.3) & 1122.6 (\(\pm\)542.9) & n. s (\(p\) = 0.327) \\ Postoperative 6 weeks & 602.6 (\(\pm\)604.9) & 487.8 (\(\pm\)574.6) & n. s (\(p\) = 0.625) \\ Postoperative 12 weeks & 626.4 (\(\pm\)686.5) & 467.7 (\(\pm\)581.1) & n. s (\(p\) = 0.534) \\ Postoperative 24 weeks & 681.8 (\(\pm\)731.3) & 573.5 (\(\pm\)665.3) & n. s (\(p\) = 0.698) \\ \hline \multicolumn{4}{c}{WOMAC Pain mean (\(\pm\)SD)} \\ Preoperative & 268.6 (\(\pm\)133.5) & 307.1 (\(\pm\)129.7) & n. s (\(p\) = 0.463) \\ Postoperative 6 weeks & 116.2 (\(\pm\)120.1) & 127.5 (\(\pm\)145.1) & n. s (\(p\) = 0.828) \\ Postoperative 12 weeks & 122.5 (\(\pm\)139.7) & 114.1 (\(\pm\)137.7) & n. s (\(p\) = 0.878) \\ Postoperative 24 weeks & 131.6 (\(\pm\)147.2) & 145.3 (\(\pm\)167.1) & n. s (\(p\) = 0.825) \\ \hline \multicolumn{4}{c}{WOMAC Stiffness mean (\(\pm\)SD)} \\ Preoperative & 110.2 (\(\pm\)61.2) & 71.5 (\(\pm\)38.4) & n. s (\(p\) = 0.070) \\ Postoperative 6 weeks & 41.8 (\(\pm\)49.3) & 39.5 (\(\pm\)47.7) & n. s (\(p\) = 0.903) \\ Postoperative 12 weeks & 50.3 (\(\pm\)59.2) & 41.5 (\(\pm\)51.6) & n. s (\(p\) = 0.692) \\ Postoperative 24 weeks & 52.7 (\(\pm\)64.0) & 46.4 (\(\pm\)55.8) & n. s (\(p\) = 0.793) \\ \hline \multicolumn{4}{c}{WOMAC Function mean (\(\pm\)SD)} \\ Preoperative & 975.4 (\(\pm\)449.2) & 744.0 (\(\pm\)397.2) & n. s (\(p\) = 0.178) \\ Postoperative 6 weeks & 444.6 (\(\pm\)449.2) & 320.8 (\(\pm\)387.9) & n. s (\(p\) = 0.462) \\ Postoperative 12 weeks & 453.6 (\(\pm\)495.9) & 312.1 (\(\pm\)397.4) & n. s (\(p\) = 0.435) \\ Postoperative 24 weeks & 497.4 (\(\pm\)530.4) & 381.8 (\(\pm\)444.9) & n. s (\(p\) = 0.556) \\ \hline \multicolumn{4}{c}{Lysholm. mean (\(\pm\)SD)} \\ Preoperative & 49.25 (\(\pm\)12.86) & 53.08 (\(\pm\)11.06) & n. s (\(p\) = 0.427) \\ Postoperative 24 weeks & 77.06 (\(\pm\)17.01) & 76.54 (\(\pm\)18.93) & n. s (\(p\) = 0.941) \\ \hline \hline \end{tabular}
\end{table} 
Table 4: Comparison of results in PRP and the control group. Figure 3: Preoperative vs postoperative total WOMAC score. Figure 4: Preoperative vs postoperative stiffness WOMAC scores. Figure 5: Preoperative vs postoperative function WOMAC scores. Figure 6: Preoperative vs postoperative pain WOMAC scores. The statistical analysis at the assumed level of significance showed that both in the control and the PRP group there are significant differences with respect to the preoperative examination. Presumably, the changes observed after six weeks are positively correlated with those observed in the following weeks. A single-factor ANOVA analysis was conducted in order to determine in detail the changes in individual parameters over time, the results of which are presented in Table 3.  
In the case of WOMAC  
potentially beneficial method of minimally invasive treatment of arthroscopic microfracturation of chondral defects in the early stages of osteoarthritis. Based on the assumptions that administration of PRP improves the mechanical and histological properties of the cartilage covering the defect, the study reported in this work set out to investigate the clinical effect of PRP augmentation of arthroscopic microfractures in elderly population. Our results show that arthroscopic microfracturation has a beneficial effect on pain and daily activities, which is represented in the decrease in WOMAC and the increase in Lysholm scores. In the past, it was widely believed that microfractures yield best effects in younger population with isolated cartilage defects [12]. Our study shows that age does not compromise the therapeutic effects in older individuals with osteoarthritis changes over 60 years of age. Moreover, good clinical outcome is shown to be attainable in as short as 6 weeks with PRP administration during MFx. Recent studies have indicated that microfractures were the treatment of choice for early osteoarthritis changes in knee and ankle joints.