## 1 Introduction  
Agriculture is facing a tremendous challenge associated with the increase in the global population, which has already surpassed 8 billion people [1]. It is estimated that by 2050 the number of humans on Earth will reach 9.1 billion, and to feed such a population, food production must increase by 70% [1]. To ensure an adequate supply of high-quality non-instrument, it is necessary to address contemporary issues related to crop losses associated with the presence of phytopathogens. Currently, up to 40% [2] of the crop yield is lost worldwide due to plant diseases, caused by various agrophages, e.g., nematodes, viruses, fungi, and bacteria. There are roughly 150 species of bacteria that are pathogenic to diverse plant species [3]. Owing to climate change, the ease of the spread of plant pathogenic bacteria and the risk of the occurrence of plant diseases will increase [4], resulting in a higher number of disease outbreaks and a notable decrease in the soil of a number of beneficial plant growth-promoting bacteria [4]. As an example, the recorded temperature changes and more frequently registered events of severe weather, such as hurricanes, may contribute to the potent expansion of the agrophages [4]. On the other hand, in addition to elongated vegetation periods, the elevated CO\({}_{2}\) concentrations may positively impact the amount of potato yields, contrarily to the quality of tubers, which, due to larger size, may possess higher concentrations of dry matter [5]. Nowadays, the commonly applied methods to control bacterial plant pathogens rely on sustainable cultivation, biocontrol, and the use of pesticides. Since the Green Revolution, pesticides have been responsible for a rise in global food productivity [6] and until today remain the main element of the integrated pest management strategy [7]. In 2021, global pesticide usage reached overall 3.53 tons, which corresponds with 2.26 kg per hectare [8]. Despite a significant role in limiting damage to crops, the application of these preparations is linked with notable drawbacks. A major hazard resulting from the usage of pesticides is the toxicity towards non-target organisms, even humans. In particular, these compounds pollute water and soil, exhibit negative impact on soil fertility, or inactivate plant beneficial microflora [9]. Furthermore, phytopathogens tend to increasingly gain resistance to chemicals [7]. In 2022, there was a proposal of Green Deal policy by the European Commission, which aims to cut down the use of chemical pesticides by up to 50% by 2030 [10]. For this reason, there is a high need for searching for alternative methods for limiting the spread of phytopathogens and, by these means, reducing losses in the food production sector. Having this in mind, one could consider applying biopesticides; however, their current scale of usage is small, as these formulations represent only 2.5% of the whole pesticide market [11]. Such a small percentage of market share is associated with several drawbacks, being a narrow spectrum of activity, short shelf lives, weather sensitivity, delayed results, and the relatively high cost of the commercially available products [12]. Another approach for substituting pesticides might be utilization of antibiotics to limit bacteria-triggered damage in crops. It needs to be stressed that antibiotics are not permitted for use against plant pathogens in the European Union (EU) [13], though they are allowed in some countries in North and South America, as well as in Asia [14]. Currently, there are at least fifteen antibiotics used in agriculture, with five most commonly implemented, i.e., streptomycin, oxytetracycline, kasugamycin, oxolinic acid, and gentamicin [14]. Sadly, the use of antibiotics to control pests in agriculture poses a significant risk of development and spread ofdrug resistance into human pathogens threatening modern medicine [7]. On this basis, we may conclude that antibiotics do not seem like a viable option in the plant protection field.