## 1 Introduction  
Wheat (_Triticum aestivum_) is the most leading cereal crops and major food source for human beings. Unfortunately, agricultural products leads to the increased the risks of the contamination of wheat particularly cadmium (Cd), leads to increase the risk of many inflammatory, metabolic and chronic diseases [1]. Contamination of wheat occurs through anthropogenic and natural sources that are major contributors to decreasing overall yield production [2]. Anthropogenic sources mainly included phosphate fertilizers, industrial emissions, and mining activities that increased the risks of accumulation of cadmium in wheat. Industrial effluents are also a major source of cadmium that enters the freshwater used for the cultivation of wheat and cereal crops including _Triticum aestivum_ L., _Oryza sativa_ L. and _Zea mays_ L [3, 4]. that uptake of cadmium in wheat occurs by roots and is then translocated into the aerial parts. Translocation of cadmium appears to be a fast process where high concentration of cadmium inhibits the growth in aerial parts and also interferes with metabolic processes like photosynthesis, respiration, transpiration, chlorophyll biosynthesis and stomatal conductance [6]. Currently, natural biostimulants are used to overcome the metal toxicity that improves the yield under stress conditions [7]. Biostimulants are rich source of diverse compounds, plant growth promoting substances with positive effects on plants. These compounds regulated the plant activities, diminished oxidative stress and promoted plant growth and developmental stages [8; 9]. Moringa leaf extract (MLE) is one of the most natural biostimulant primarily containing higher nutrient contents that help the plant to improve growth and inhibit the cadmium phytotoxicity in many crops such as _Tritcium aestivum_ L., _Phaseolus vulgaris_ L. and _Lepidium sativum_ L. [10]. According to numerous investigations, MLE is also a rich source of antioxidants, amino acids, riboflavin, ascorbic acid folic acid, pyridoxine, vitamins such as A, B and C, which are essential for the control of physiological, metabolic, enhanced development, yield attributes and zeatin that regulate the physiological and biochemical processes and improve the yield under harsh environmental conditions [11; 12]. MLE is also used for the absorption of toxic metals such as cadmium in soils due to the presence of thiol-containing proteins that biochemically interact hydroxyl group of cadmium. It has been reported that the application of MLE improved the antioxidant enzyme system of wheat. It also reduced the oxidative stress from free radicals species that occurred under high concentrations of cadmium [13]. Fluctuations of plant growing conditions such as temperature, light, humidity, nut rient availability etc. during growing season can have unpredictable effects on plant yield. Such as, changes in solar radiation is one of the factors controlling grain yield. Increased light intensity stimulates leaf production, and it enhances the number of leaves and shoots of plants under light. The intensity of light affects the plant characteristics. Plants grown under shade are more susceptible to photoinhibition, while on the other hand, low light may also result in an over excitation of electron transport systems, potentially resulting (ROS) that promotes oxidative stress, such as hydrogen peroxide, superoxide, and singlet oxygen. The excess of these ROS affects the production of macromolecules, disrupts the antioxidant activities, and decreases plant height, root length, soluble proteins and antioxidant enzyme activities [6; 14]. Keeping in view literature reported, there is a lack of necessary information for revealing the potential of MLE for decreasing the Cd tolerance in wheat. To the best of our knowledge, this type of approach with MLE soil application was not reported in the literature before.