## 3 Results
### Patients' Characteristics and Interventions Received in the First and Second Wave
\begin{table}
\begin{tabular}{c c c} \hline \hline \multicolumn{2}{c}{**First Wave (n = 690)**} & \multicolumn{2}{c}{**Second Wave (n = 903)**} \\ \hline  & **Mean \(\pm\) SD; Median (IQR) or n (\%)** & **Mean \(\pm\) SD; Median (IQR) or n (\%)** \\ \hline \multicolumn{2}{c}{**Clinical Characteristics**} \\ \hline
**Signs and Symptoms at** & & \\
**Admission** & & \\ \hline Systolic blood pressure (mmHg) & 134.55 \(\pm\) 156.80; 125.79 (116.88–138.17) & 177.25 \(\pm\) 1414.32; 127.00 (117.50–137.25) & \\ \hline Pulse (beats per minute) & 84.35 \(\pm\) 11.86; 83.79 (76.00–91.73) & 84.35 \(\pm\) 27.40; 81.67 (74.20–91.05) & \\ (n = 612) & (n = 823) & 0.012 \\ \hline Respiratory rate (breaths per minute) & 19.15 \(\pm\) 3.22; 18.33 (17.50–20.00) & 18.87 \(\pm\) 3.46; 18.00 (17.40–19.50) & \\ (n = 586) & (n = 769) & 0.076 \\ \hline Pulse oximetry (\%) & 93.51 \(\pm\) 11.66; 95.33 (92.00–97.00) & 92.33 \(\pm\) 6.48; 94.00 (90.00–96.57) & \\ (n = 550) & (n = 765) & \(<\) 0.01 \\ \hline Glasgow coma scale & 14.75 \(\pm\) 1.38; 15.00 (15.00–15.00) & 14.83 \(\pm\) 0.86; 15.00 (15.00–15.00) & \\ (n = 615) & (n = 820) & 0.140 \\ \hline \multicolumn{2}{c}{**Comorbid Conditions**} \\ \hline Any comorbidity & 482 (70.6) & 722 (80.0) & \\ (n = 683) & (n = 903) & \(<\)0.01 \\ \hline Hypertension & 321 (47.1) & 482 (53.5) & \\ (n = 682) & (n = 901) & 0.013 \\ \hline Cardiovascular diseases & 168 (24.6) & 252 (28.1) & \\ (n = 683) & (n = 898) & 0.137 \\ \hline Diabetes & 147 (21.5) & 160 (17.8) & \\ (n = 683) & (n = 899) & 0.100 \\ \hline Malignancy & 113 (16.5) & 194 (21.6) & \\ (n = 683) & (n = 899) & 0.015 \\ \hline Neurological diseases & 97 (14.3) & 176 (19.6) & \\ (n = 679) & (n = 897) & 0.007 \\ \hline Respiratory diseases & 92 (13.5) & 136 (15.1) & \\ (n = 683) & (n = 900) & 0.396 \\ \hline Chronic kidney diseases & 54 (7.9) & 94 (10.4) & \\ (n = 681) & (n = 900) & 0.107 \\ \hline \multicolumn{2}{c}{**Laboratory Characteristics**} \\ \hline
**Blood Routine** & & \\ \hline White blood cells (\(\times 10^{9}/\)L; & 8.45 \(\pm\) 7.33; 6.89 (5.22–10.08) & 8.83 \(\pm\) 12.85; 7.40 (5.39–10.12) & \\ normal range 4.0–10.0) & (n = 638) & (n = 866) & 0.998 \\ \hline Eosinophils (\(\times 10^{9}/\)L; normal & 0.03 \(\pm\) 0.09; 0.00 (0.00–0.00) & 0.02 \(\pm\) 0.06; 0.00 (0.00–0.00) & \\ range 0.0–0.5) & (n = 650) & (n = 881) & 0.027 \\ \hline Monocytes (\(\times 10^{9}/\)L; normal & 0.63 \(\pm\) 0.65; 0.50 (0.40–0.80) & 0.70 \(\pm\) 2.17; 0.50 (0.40–0.80) & \\ range 0.2–0.8) & (n = 650) & (n = 881) & 0.059 \\ \hline Basophils (\(\times 10^{9}/\)L; normal & 0.01 \(\pm\) 0.04; 0.00 (0.00–0.00) & 0.02 \(\pm\) 0.04; 0.00 (0.00–0.00) & \\ range 0.0–0.1) & (n = 650) & (n = 881) & 0.330 \\ \hline Lymphocytes (\(\times 10^{9}/\)L; normal range 1.0–4.0) & 1.31 \(\pm\) 5.31; 0.90 (0.60–1.30) & 1.40 \(\pm\) 11.12; 0.90 (0.60–1.20) & \\ (n = 650) & (n = 881) & \(<\)0.01 \\ \hline Platelets (\(\times 10^{9}/\)L; normal & 228.09 \(\pm\) 105.68; 212.00 (158.00–275.50) & 228.83 \(\pm\) 106.86; 211.00 (161.00–277.00) & \\ range 150–400) & (n = 651) & (n=881) & 0.338 \\ \hline Hemoglobin (g/dL; normal & 13.44 \(\pm\) 2.04; 13.70 (12.30–14.80) & 13.22 \(\pm\) 2.13; 13.40 (12.00–14.60) & \\ range 13.0–16.0) & (n = 651) & (n = 881) & 0.001 \\ \hline \hline \end{tabular}
\end{table} 
Table 1: _Cont._