## 1 Introduction  
Polymeric nano and micron-sized particles are extensively used in various areas, such as for paints and coatings, oil and gas explorations, adhesives, composites, cosmetics, personal grooming products, medicine and for fabrication of medical devices, life sciences, biotechnology, etc. [1] Particularly in recent years, the uses of submicro-/ microparticles derived from natural and synthetic polymers have been investigated more for biomedical applications. The production methods of polymer microparticles have become increasingly important for applications such as controlled drug delivery, medical diagnostic tests, obtaining superhydrophobic surfaces, optimum design of toughened polymeric composites and food technology [2; 3; 4]. Suspension or emulsion polymerization, solvent evaporation, spray drying, spraying a polymer solution through a small hole and the Shirasu Porous Glass (SPG) membrane emulsification technique are the methods used to produce polymeric microparticles. However, conventional manufacturing methods have many drawbacks such as the fact that they are time-consuming, the coalescence among particles and obtaining of non-homogeneous particle sizes and non-uniformity of shapes [5]. These limitations can be overcome by introducing the electrospray method. In addition to this, the electrospray method has huge advantages over traditional methods in terms of generating little residue, using fewer solvents, being low-cost and using high molecular weight polymers [6]. The electrospray method became widespread with the use of ions as a method for mass spectrometry analysis [7]. Electrospray is an electrohydrodynamic process in which monodisperse droplets are formed by passing a liquid of sufficient electrical conductivity through a capillary channel or nozzle to a high potential [8]. Further, the electrospray technique is capable of producing droplets of different sizes and shapes from solutions with high viscosity. The production of the droplets with the desired size is a vital processing step in advanced engineering applications such as dispersion and particle production [9]. Electrospraying can be influenced by many variable parameters, such as electrostatic field strength, needle size solution flow rate and conductivity, physical properties and concentration [10]. The microparticles produced by these techniques are usually monodisperse, and the size of these particles can be easily controlled by varying the flow rates [11]. Additionally, it is a potential process to fabricate particles with a small amount of material with minimum losses. Thus, it has features such as simplicity and easy applicability [12]. Compared to traditional production methods, the electrospray method has several unique superiorities, including an improved encapsulation ability of hydrophilic and hydrophobic agents, strict control over particle size, excellent particle reproducibility and obtaining particle size micron to the submicron range [13]. The electrospray method is a remarkable role in pharmacological applications due to its ability to form smaller particles, better size distribution and less agglomeration [14]. In the previous report, [PERSON] et al. demonstrated a method of producing monodispersed polymeric microparticles with uniform size and surface morphology using low molecular weight polystyrene with the electrospray method [5]. In another work, [PERSON] et al. produced micro- and nanoparticles of chitosan using a one-step electrospray method. Nanospheres with a size of around 128 nm were obtained from a 22 G needle under an effective voltage of 33 kV with a 0.2 mL/s flow rate [15]. Biodegradable polymeric porous microparticles are used in tissue regenerative medicine; various applications in pharmaceutical science, for example, use biomedical applications, such as for controlled drug delivery [16]. Pore structure and porosity are the main factors that govern controlled drug release in particular applications. Porous microparticles have very low mass densities and large surface areas.