## 3 Results
### Metabolic Variables  
Table 3 shows the mean and standard deviation values of metabolic variables (HbA1c, HDL, LDL, and TG) in both groups before and after the intervention. Additionally, results from the repeated-measures ANOVA are presented, including the main effect of time and the time \(\times\) group interaction.  
A significant group \(\times\) time interaction was observed for HbA1c (F(1,72) = 1351.57, \(p<0.001\), \(\eta^{2}_{\text{P}}\) = 0.952), indicating a differential effect between groups over time. Post hoc analyses confirmed a significant reduction in HbA1c in the algae-based supplement group (\(p<0.001\)), while the control group showed a significant increase (\(p<0.001\)). The between-group difference at post-intervention was also statistically significant (\(p<0.001\)).  
Similarly, a significant interaction effect was found for LDL cholesterol (F(1,68) = 6893.35, \(p<0.001\), \(\eta^{2}_{\text{P}}\) = 0.990). Post hoc tests revealed a significant decrease in LDL levels in the algae-based supplement group (\(p<0.001\)) and a slight, non-significant increase in the control group. The between-group difference at post-intervention was significant (\(p<0.001\)).  
\begin{table}
\begin{tabular}{c c c c} \hline \hline
**Variable** & **Category** & \
\begin{tabular}{c} **Algae Supplement** \\ **Group, n (\%)** \\ \end{tabular} &
\begin{tabular}{c} **Control Group, n** \\ **(\%)** \\ \end{tabular} \\ \hline \multirow{3}{*}{Lactose Intolerance} & High risk & 3 (4.3\%) & 1 (1.4\%) \\ \cline{2-4}  & Low risk & 20 (28.6\%) & 21 (30.0\%) \\ \cline{2-4}  & Medium risk & 12 (17.1\%) & 13 (18.6\%) \\ \hline \multirow{3}{*}{Fructose} & Low risk & 28 (40.0\%) & 27 (38.6\%) \\ \cline{2-4}  & Medium risk & 7 (10.0\%) & 8 (11.4\%) \\ \hline \multirow{3}{*}{Blood Clot Risk} & Average & 21 (30.0\%) & 21 (30.0\%) \\ \cline{2-4}  & At risk & 5 (7.1\%) & 5 (7.1\%) \\ \cline{2-4}  & Protected & 9 (12.9\%) & 9 (12.9\%) \\ \hline \multirow{3}{*}{Vitamin D Levels} & Average & 15 (21.4\%) & 15 (21.4\%) \\ \cline{2-4}  & High levels & 6 (8.6\%) & 5 (7.1\%) \\ \cline{2-4}  & Low levels & 14 (20.0\%) & 15 (21.4\%) \\ \hline \multirow{3}{*}{Vitamin B12 Levels} & Average & 14 (20.0\%) & 17 (24.3\%) \\ \cline{2-4}  & High levels & 11 (15.7\%) & 8 (11.4\%) \\ \cline{2-4}  & Low levels & 10 (14.3\%) & 10 (14.3\%) \\ \hline \hline \end{tabular} Values are expressed as absolute frequencies and percentages (%), where the percentage indicates the proportion of participants within each group who presented a given genetic category. No significant differences were observed between groups in the distribution of any genotype (\(p>0.05\) for all comparisons, chi-square test).  
\end{table}
Table 2: _Cont._Triglycerides (TGs) also showed a significant group \(\times\) time interaction (F(1,68) = 1574.76, \(p\) < 0.001, \(\eta^{2}_{\rm P}\) = 0.959). While the algae-based supplement group experienced a notable reduction (\(p\) < 0.001), the control group showed an increase, with a significant difference observed between groups at post-intervention (\(p\) = 0.041).  
Finally, for HDL cholesterol, the interaction effect was significant though with a smaller effect size (F(1,68) = 6344.15, \(p\) < 0.001, \(\eta^{2}_{\rm P}\) = 0.989). Post hoc comparisons showed a decrease in HDL levels in the algae-based supplement group and an increase in the control group. The between-group difference post-intervention was significant (\(p\) = 0.026), although the clinical interpretation may require caution due to the divergent nature of the response.