## Materials and Methods
### CMF Water Treatment with a Series of Dilutions and Vigorous Shaking  
In addition to the experiments with direct exposure of neutrophil suspension to the CMF (described in the subsection \"Neutrophil suspension exposure to the combined magnetic field\"), we performed studies in which water samples used for the subsequent preparation of neutrophil suspensions were similarly exposed to the natural (GMF) or various artificial (CMF, \"magnetic vacuum\") magnetic fields. More detailed description of the magnetic fields, at which water exposure was carried out, are presented below in the relevant subsections. Water sample exposure to the CMF was performed in 18 mL optic glass spectrophotometric cubic cuvettes (Hellma Analytics, Germany, Cat. No. 704-001-30-10) and lasted for 40 min in the magnetic field induction device (described in \"CMF generation\") at room temperature (23-24 \({}^{\circ}\)C). Moreover, 20 h prior to the CMF exposure, water samples were purified to high degree (specific resistance of 18.2 MOhm-cm at 25 \({}^{\circ}\)C, at the time of purification). The exposed water samples were then added to the suspension of intact neutrophils under the GMF, and the intensity of cell chemiluminescence was measured (using the procedure described in the Materials and Methods subsection \"Measurement of luminol-enhanced cell chemiluminescence\"). 5.1 Sample Preparation for Investigation of Water-Mediated Activation of Neutrophils. The Role of Dilutions, Magnetic Vacuum, and Methods of Mechanical Treatment  
The experiment included five groups of water samples, some of which were exposed to both magnetic field and the serial dilution process. \"Control\" sample was purified water incubated outside the magnetic field induction device (under the GMF conditions). The results of all other measurements were normalized according to the results of these sample measurements. \"Experimental\" sample was a water sample similar to \"Control\" sample, but incubated under the CMF conditions with static component of 60 uT and alternating component of 100 nT formed according to the sinusoidal regime with 12.6 Hz frequency. The resulting \"Experimental\" sample was divided into four parts: \begin{table}
\begin{tabular}{c c c c c} \hline \hline \multirow{2}{*}{**AMF Parameters**} & \multicolumn{4}{c}{**Chemiluminescence Intensity**} \\ \cline{2-5}  & \multicolumn{2}{c}{**Control**} & \multicolumn{2}{c}{**Experimental**} \\ \cline{2-5}  & \% & **V** & \% & **V** \\ \hline
12.6 Hz, 100 nT & 100 \(\pm\) 3.0 & 4.23 \(\pm\) 0.13 & 136.6 \(\pm\) 8.6 &
\begin{tabular}{c} 5.78 \(\pm\) 0.50 \\ \(p\) = 0.002165 \\ \end{tabular} \\ \hline
48.5 Hz, 100 nT & 100 \(\pm\) 6.8 & 4.33 \(\pm\) 0.29 & 81.5 \(\pm\) 8.4 &
\begin{tabular}{c} 3.53 \(\pm\) 0.30 \\ \(p\) = 0.002165 \\ \end{tabular} \\ \hline \hline \end{tabular} All measurements were performed in six replicates. Intergroup statistical comparison was made relative to control group. The conditions of sample preparation are described in detail in the section “Materials and methods: Neutrophil suspension exposure to the combined magnetic field”. Data is presented as M \(\pm\) SD.  
\end{table} 
Table 2: Intensity of chemiluminescence (maximum value) of neutrophil suspension after direct exposure to CMF (with static component of 60 uT and varying conditions of alternating magnetic field (AMF)). 1. Homonymous \"Experimental\" sample measured without any additional exposure. 2. \"GMF, dilution factor 1099\"--the sample was subjected to 50 serial centesimal dilutions with vigorous shaking between dilution steps. Both dilution and shaking procedures were performed under the GMF conditions (outside the magnetic field induction device). 3. \"Magnetic vacuum\", dilution factor 1099\"--the sample was subjected to 50 serial centesimal dilutions with vigorous shaking between dilution steps. However, dilutions were made under the GMF conditions and each shaking was performed inside the magnetic field induction device with disconnected power supply and with residual magnetic field intensity \(\sim\)10 nT.