## 3 Results
### Haematological Parameters
#### 3.6.2 White Blood Cells
\begin{table}
\begin{tabular}{c c c c c c} \hline \hline \multirow{2}{*}{**Heamological Parameter**} & \multirow{2}{*}{**Days Post T. zinhabitucensis Infection**} & \multicolumn{4}{c}{**Experimental Groups**} \\ \cline{3-6}  & & **Tz** & **D** & **TzD** & **Range of Reference Values** \\  & & Day 35 & 0.25 (0.20-0.42) & 0.20 (0.0-0.22) & 0.20 (0.10-0.35) & \\ \hline \multirow{6}{*}{Eosinophilis (\%)} & Day 0 & 0.65 (0.55-1.40) & 1.00 (0.77-1.12) & 1.00 (0.77-1.12) & 0.54-3.39 \\  & Day 7 & 2.05 (1.65-2.45) & 2.40 (1.12-31.37) & 0.60 (11.7-0.82) & \\  & Day 14 & 2.45 (0.51-3.10) & 1.50 (1.30-2.90) & 4.40 (29.5-4.35) & \\  & Day 21 & 4.70 (1.55-4.67) & 1.90 (0.85-4.47) \({}^{\star}\) & 6.60 (5.70-9.35) \({}^{\star}\) & \\  & Day 28 & 3.60 (2.42-4.95) & 1.00 (0.35-1.40) \({}^{\star}\) & 2.20 (1.55-3.25) & \\  & Day 35 & 2.05 (1.40-3.32) & 1.20 (0.97-3.00) \({}^{\star}\) & 7.80 (3.5-9.30) \({}^{\star}\) & \\ \hline \multirow{6}{*}{Haemoglobin (\%)} & Day 0 & 14.80 (12.75-15.83) & 14.35 (13.40-15.35) & 14.35 (13.40-15.35) & 13.50-15.90 \\  & Day 7 & 15.45 (13.53-17.13) & 13.95 (13.53-17.13) & 16.00 (14.58-17.23) & \\  & Day 14 & 16.55 (12.53-17.30) & 15.60 (15.25-16.95) & 15.10 (13.90-16.15) & \\  & Day 21 & 14.00 (13.58-15.08) & 16.60 (15.95-17.10) \({}^{\star}\) & 16.60 (15.75-17.75) \({}^{\star}\) & \\  & Day 28 & 13.60 (13.43-14.60) & 14.50 (14.06-16.88) & 14.30 (14.10-15.30) & \\  & Day 35 & 15.70 (15.23-16.40) & 14.60 (13.95-15.25) & 14.10 (13.50-15.85) & \\ \hline \multirow{6}{*}{Platelets (\(10^{6}/L\))} & Day 0 & 1006 (025.0-1086) & 1167 (1123-1207) & 1167 (1123-1207) & 923–1580 \\  & Day 7 & 1037 (1007-112) & 1024 (0.943-1082) & 1027 (0995-1206) & \\ \cline{1-1}  & Day 14 & 1011 (94.78-1071) & 9503 (95.93-95.96) & 756.08 (0.80-0.435) & \\ \cline{1-1}  & Day 21 & 801 (791.91-92.02) & 938.08 (97.15-1049) & 1056 (1000-1087) \({}^{\star}\) & \\ \cline{1-1}  & Day 28 & 9205 (868.3-1005) & 1111 (890.1-1156) & 984 (028.5-96.5) & \\ \cline{1-1}  & Day 35 & 1264 (1002–1376) & 964.5 (0.852-3.003) \({}^{\star}\) & 1072 (983.0-1191) & \\ \hline \hline \end{tabular}
\end{table} 
Table 3: _Cont._Percentage of lymphocytes was within the reference value range in all experimental groups on day 0, 7 and 14 pi when compared with reference values (69.68-86.89). At day 21 pi, the percentage lymphocytes were low in some animals, while some were within the reference value in Tz (66.90-75.13), the D (63.35-69.90) and TzD (60.10-67.55) were below the reference value when compared to (69.68-86.89). Additionally, at day 28 pi, a decrease was observed in the D (63.90-79.23) and TzD (64.85-75.80) groups, although some values were within the reference value (69.68-86.89). Percentage lymphocytes were below the reference value range in all the experimental groups, Tz (65.23-75.75), D (43.78-54.20) and TzD (41.00-57.45) at day 35 pi when compared to the reference value (69.68-86.89), although some values were within the reference range in the Tz. Lymphocytes were significantly lower (\(p<0.001\)) in both the D and TzD at day 35 pi compared to the Tz group, and a reduced percentage of lymphocytes was also observed at day 21 and 28 pi; however, this was not significant (Table 3). Basophil concentration was within the reference value range in the Tz group on day 7 pi, and slightly higher in the D (0.15-0.47) and TzD (0.30-0.62) groups, respectively, when compared to the reference values (0.04-0.44). There was an elevation of basophils (%) in the TzD group at day 21 pi (0.05-0.50) when compared to (0.04-0.44). Additionally, there was an increase at day 28 pi in the D (0.35-0.60) group when compared to (0.04-0.44), although some values were still within the reference range. All differences observed among experimental groups were not significant (Table 3). Eosinophil levels were lower than the reference value range in the TzD group on day 7 pi (0.17-0.82), while on day 14 pi (2.95-6.35), the eosinophils levels were within the reference values in some animals, while some were higher when compared with the reference values (0.54-3.39).