###### Abstract  
In this paper, a new method for the preparation of a molecularly imprinted polymer (MIPs)-coated magnetic stir bar for bisphenol A (BPA) is proposed. The MIPs were prepared using BPA as the template molecule, and the sol-gel technique was employed to coat the MIPs onto the surface of a glass tube, which contained an internal magnetic core. The morphology and structure of the MIPs and the coating on the glass stir bar were analyzed using scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FT-IR). Parameters affecting the extraction efficiency, such as extraction time, stirring speed, desorption solvent, and desorption time, were optimized. To evaluate the selective adsorption performance of the BPA-MIPs coating, molecularly imprinted stir bar sorptive extraction (MIPs-SBSE) was used in combination with high-performance liquid chromatography (HPLC) for the detection of BPA in deionized water, tap water, bottled water, and reservoir water. The results showed that under the optimized conditions, the MIPs coating exhibited better adsorption capacity and selectivity for BPA compared to the non-imprinted coating. The BPA-MIPs-SBSE could be reused for at least five cycles without a significant decrease in its selective adsorption ability. The recoveries of BPA in the four actual water samples ranged from 70.53% to 93.10%, with relative standard deviations of 4.49% to 8.69%. The practical application demonstrated that this method is simple, convenient, selective, and sensitive, making it suitable for the analysis and detection of trace amounts of BPA in complex samples. bisphenol A; molecularly imprinted polymer; sol-gel method; stir bar sorptive extraction Article Preparation of Molecularly Imprinted Magnetic Stir Bar for Bisphenol A and Its Analysis on Trace Bisphenol A and Its Analysis on Trace Bisphenol A in Actual Water Samples [PERSON]  
1 AECC Shenyang Engine Research Institute, Shenyang 110015, China; [EMAIL_ADDRESS]  
2 State Key Laboratory of Urban Water Resource and Environment, School of Environment, Harbin Institute of Technology, Harbin 150090, China; [EMAIL_ADDRESS] (Z.W. ); [EMAIL_ADDRESS] (Z.C. ); [EMAIL_ADDRESS] (Z.C. ); chenzhonglin_hit@163. Currently, the main analytical methods for detecting BPA include high-performance liquid chromatography (HPLC), gas chromatography (GC), chemiluminescence (CL), and enzyme-linked immunosorbent assay (ELISA). However, due to the complexity of real samples and the presence of trace amounts of BPA in various forms, appropriate sample pretreatment is necessary before applying these analytical methods [4; 5; 6]. Existing sample pretreatment techniques include solid-phase extraction (SPE), liquid-liquid extraction, stir bar sorptive extraction (SBSE), solid-phase microextraction (SPME), liquid-phase microextraction, dispersive liquid-liquid extraction, matrix solid-phase dispersion, and ultrasound-assisted extraction [4; 5; 6]. Among these techniques, SBSE has gained wide popularity as a novel and effective sample pretreatment method. Its advantages over SPME lie in its larger adsorption capacity and higher extraction efficiency. SBSE can achieve the enrichment of target analytes through self-stirring, thus avoiding the competitive adsorption brought by external stirring. Despite being proposed as early as 1999, SBSE has made significant progress only in the past decade. In its early applications, PDMS was used as the coating material. PDMS, being nonpolar, exhibited good affinity for nonpolar compounds but weaker affinity for polar compounds. Therefore, researchers have proposed several new types of stir bar coatings, such as composite coatings [7; 8; 9], biphasic coatings [10; 11], polymer phase coatings [12; 13; 14; 15; 16], integral coatings [17; 18; 19], restricted access material coatings [20], cation exchange membrane coatings [21], zirconia coatings [22], C18 coatings [23], graphene [24], and polydimethylsiloxane/metal-organic framework coatings [25].