Studies indicate that, once inside the human body, they can accumulate in the intestine, causing local inflammation, altering the endocrine system, and affecting gastrointestinal functions [9]. Unfortunately, agricultural soils receive these MPs on a regular or constant basis through the use of plastic mulches, the use of biosolids and composs as organic amendments, irrigation with treated water, etc. However, the effects of MPs are still being investigated and, due to their non-biodegradability, they may bioaccumulate with a high toxicity in many organisms [10]. It is estimated that there are from 4 to 23 times more MPs in terrestrial environments than in aquatic environments [11], and concentrations of up to 7% of MPs have been reported in highly contaminated soils [4,12]. Due to its structure, different chemical composition, and surface properties, plastic generates a series of abrupt changes in the physical, chemical, and biological properties of soil [13]. [PERSON] et al. [14] used sandy loam soil with different MPs in different forms and found that these decreased soil aggregates. Moreover, due to the low density of most plastics, they tend to decrease the apparent density of soil [15]. These antecedents indicate that these physical changes are closely related to other changes at the chemical and biological levels. The COVID-19 pandemic had a high impact on the use and disposal of medical plastic waste, especially face masks, causing a global crisis in their management. The improper management of face masks can cause various effects on the environment, animals, and humans [16]. According to estimates by the World Health Organization (WHO), approximately 89 million face masks were demanded each month to deal with the spread of COVID-19 [17]. However, after COVID-19, the use of single-use protective equipment by the population has increased to an estimated global consumption of 129 billion face masks [18]. A recent finding showed that 8.4 \(\pm\) 1.4 million tons of pandemic-associated plastic waste had been generated in 193 countries as of 23 August 2021 [19]. Furthermore, according to empirical data, the supply of medical plastic waste will continue to increase at an annual rate of 20% between 2020 and 2025, which could produce approximately 20.9 million tons of medical plastic waste in 2025 [20]. Furthermore, it was estimated that the increase in plastic waste would reach 250 million metric tons by 2025 [21], indicating that waste from single-use protective equipment could represent 8.36% of the total amount of plastic waste [22]. This demand has led to an unprecedented increase in the global production of face masks made from polymeric materials. New sources of MPs fibers are, therefore, emerging, since these disposable (single-use) face masks can fragment or decompose in the environment to sizes smaller than 5 mm [17]. Once face masks are discarded into the environment, they undergo physical processes that cause them to fragment into smaller plastic particles, which eventually become MPs [23]. These fragmented plastic particles are resistant to further degradation and can persist in the environment for up to 450 years [24]. This causes an increase in MP concentrations, especially in soil. Due to the abovementioned issues, it is important to determine the effects that MPs from disposable face masks can have on the different physicochemical, biological, and ecophysiological properties of soil. On the other hand, it is also important to determine their effects on the quality level of soils containing these MPs. Unfortunately, the existing studies related to soil with MPs only focus on their effects on certain properties of the soil, and not on the quality of the soil as a whole. For example, [PERSON] et al. [25], in a very similar study at the microcosm level for 92 days, determined that a concentration of 5% (w w\({}^{-1}\)) of these face mask MPs decreased the soil's bulk density (BD) and cation exchange capacity (CEC); on the other hand, it increased the soil's pH and total organic carbon (TOC).