## 3 Results and Discussion
[PERSON] and coworkers indicated the influence of EB irradiation on the hydrolytic degradation of PLGA films without an analysis of the changes in  
\begin{table}
\begin{tabular}{c c c c c c c c c c} \hline \hline  & & & & & & & & & \\ \hline
**Time** & \(F_{LL}\) & \(F_{GG}\) & \(F_{TMC}\) & \(\Delta H\) (\(\text{J/g}\)) & \(T_{g}\) (\({}^{\circ}\)C) & \(M_{n}\) & \(D\) & _WUI_ (\%) & _WL_ (\%) \\ \hline
0 & 62.7 & 19.4 & 17.9 & _ND_ & _ND_ & 39.9 & 42.2 & 2.061 & 0 & 0 \\
1 & 63.1 & 18.9 & 18.0 & _ND_ & 45.7 & 42.0 & 2.026 & 1.2 & 7.6 \\
15 & 63.1 & 18.6 & 18.3 & _ND_ & _ND_ & 43.5 & 34.3 & 2.365 & 3.0 & 15.0 \\
29 & 63.1 & 18.6 & 18.3 & _ND_ & _ND_ & 42.3 & 22.0 & 2.222 & 3.2 & 16.4 \\
43 & 62.3 & 18.4 & 19.3 & 81.5 & 8.1 & 39.4 & 12.2 & 2.313 & 5.6 & 17.2 \\
57 & 64.5 & 16.8 & 18.7 & 83.8 & 17.0 & 32.4 & 5.0 & 3.031 & 12.4 & 18.7 \\
71 & 66.4 & 15.6 & 18.0 & 88.4 & 26.6 & 33.3 & 2.1 & 1.622 & 46.8 & 49.0 \\
85 & 65.6 & 16.1 & 18.3 & 94.1 & 31.5 & 29.6 & 1.9 & 1.537 & 78.2 & 69.7 \\
99 & 67.8 & 15.3 & 16.9 & 85.5 & 29.6 & 33.1 & 1.9 & 1.544 & 88.6 & 84.1 \\
113 & 69.9 & 14.0 & 16.1 & 91.3 & 39.1 & 30.1 & 1.8 & 1.662 & 97.1 & 98.2 \\ \hline \hline \multicolumn{10}{c}{**EB-P(l-LA:GA:TMC) Matrix-LTP**} \\ \hline
**Time** & \(F_{LL}\) & \(F_{GG}\) & \(F_{TMC}\) & \(\Delta H\) (\(\text{J/g}\)) & \(T_{g}\) (\({}^{\circ}\)C) & \(M_{n}\) & \(D\) & _WUI_ (\%) & _WL_ (\%) \\ \hline
0 & 62.5 & 19.7 & 17.8 & _ND_ & _ND_ & 43.3 & 29.5 & 2.255 & 0 & 0 \\
1 & 63.1 & 18.9 & 18.0 & _ND_ & _ND_ & 37.9 & 29.0 & 2.308 & 2.3 & 3.8 \\
15 & 63.5 & 18.1 & 18.4 & _ND_ & _ND_ & 36.0 & 20.6 & 2.384 & 3.2 & 11.7 \\
29 & 63.5 & 18.1 & 18.4 & _ND_ & _ND_ & 35.8 & 10.3 & 2.460 & 5.5 & 12.5 \\
43 & 62.7 & 17.9 & 19.4 & 79.7 & 4.8 & 34.1 & 4.2 & 2.502 & 35.0 & 15.5 \\
57 & 63.3 & 18.4 & 18.3 & 80.2 & 12.1 & 27.8 & 2.3 & 1.804 & 49.2 & 32.1 \\
71 & 64.9 & 18.0 & 17.1 & 81.1 & 17.7 & 28.9 & 2.2 & 1.822 & 65.7 & 53.1 \\
85 & 65.4 & 16.3 & 18.3 & 83.8 &polymer composition during degradation [66]. For EB-P(l-LA:GA:TMC) matrix-LTP, the EB irradiation did not result in significant changes in the unit distribution of the native matrix. However, during degradation, more dynamic changes for \(F_{LL}\), \(F_{GG}\), and \(F_{TMC}\) to the final values of 76.0 mol%, 12.2 mol%, and 11.8 mol%, respectively, were observed (Table 2). Analogous results were obtained for the degradation of non-irradiated and EB-irradiated P(l-LA:GA:TMC) rods with aripiprazole [46]. The DSC analysis revealed that initially amorphous matrices (Table 1) changed the character and/or the matrix structure underwent a process of ordering during degradation. During the first heating run for P(l-LA:GA:TMC) matrix-LTP, between the 43 rd and 113 th days of degradation, endothermic peaks with maxima ranging from 81.5 \({}^{\circ}\)C to 94.1 \({}^{\circ}\)C were observed (Figure 2, Table 2). These observations are consistent with degradation studies on the degradation of l-PLGA copolymer and P(l-LA:GA:TMC) terpolymers [40; 44; 46]. In this study, the second heating run for P(l-LA:GA:TMC) matrix-LTP showed a decreasing trend for the \(T_{g}\) in the range from 45.7 \({}^{\circ}\)C to 29.6 \({}^{\circ}\)C with fluctuations in values (Figure 2, Table 2). EB irradiation influenced the chain scission of P(l-LA:GA:TMC) [46]. The values of the \(T_{m}\), \(\Delta H\), \(T_{g}\), and \(M_{n}\) during the 1 st and 85 th day of degradation were the result of this phenomenon (Figure 2, Table 2). The \"homogenization\" or \"unification\" of the terpolymer chain can be mentioned here. Clear and visible differences in the degradation characteristics of P(l-LA:GA:TMC) matrix-LTP and EB-P(l-LA:GA:TMC) matrix-LTP are shown in the intensity changes in parameters such as the \(M_{n}\), \(WU\), and \(WL\) (Figure 3, Table 2). In the case of aliphatic polyesters and polyester carbonates, the degradation has a hydrolytic character and results from the hydrolysis of ester bonds [42]. Therefore, degradation changes are closely related to the susceptibility of \(WU\).