# A Concise Review of Silver Diamine Fluoride on Oral Biofilm
## 2 Materials and Methods
\begin{table}
\begin{tabular}{c c c c c c}
**Author, Year** & **Setting; Substrate** & **Microbiota** & **Period;** & **Intervention** & **Antibacterial Effect** \\  & & & & **Assessment** & & **CFU 15 min** \\  & & & & & **Gp1: Ca(OH)2** & **Gp2, Grp3** \textless{} Gp1, \\ [PERSON] et al., 2010 & In vitro; human dentin & _E. faecalis_ & 15 min, 60 min; CFU & **Gp2: SDF** & **Gp4** \\  & & & & **CFU 603: NaOCl** & **CFU 60 min:** \\  & & & & **Gp4: NaCl** & **G2, Grp3 had no** _E. faecalis_ \\  & In vitro; human dentin & _S. mutans_, _A. naslundii_ & 7 days; CFU, CLSM & **Gp1: SDF** & **CFU: Grp1 \textless{} Gp2** \\ [PERSON] et al., 2013a & In vitro; human dentin & _S. mutans_ & 7 days; GP1: SDF** & **CFU: Grp1 \textless{} Gp2** \\  & & _L. acidophilus_ & **CFU, CLSM** & **Gp2: Water** & **CLSM: Grp2 \textless{} Gp1** \\  & & _Consortium of_ & _S. mutans_, _S. subruns_, _S. mutans_, _S. subruns_, _L. acidophilus_, _L. rhamnus_, _A. naslund_ & **7 days, 14 days, 21 days; CFU, CLSM** & **Gp1: SDF** & **CFU: Grp1 \textless{} Gp2** \\  & & & & **CFU, CLSM** & **Gp2: Water** & **CLSM: Grp2 \textless{} Gp1** \\  & & & & **BL, 3 days, 6** & & \\ [PERSON] et al., 2013 & In vivo & _S. mutans_ & 12 months, 18 months; CFU & **Gp1: SDF** & **CFU: Grp2** \\  & & & & **12 months, 18 months; CFU** & **Gp2: NaF + CaF** & **Gp1 \textless{} Gp2** \\  & & & & **Gp3: APF gel** & **Gp1 \textless{} Gp3** \\ [PERSON] et al., 2015 & In vitro; bovine enamel & _S. mutans_ & 7 days; TBC, pH & **Gp1: Water** & **Antibacterial activity:** \\ [PERSON] et al., 2017 & In vitro; bovine dentine & _L. rhamnus_ & 6 days; CFU & **Gp1: Water** & **CFU: Grp2** \textless{} Gp1** \\  & & & & & **Gp2: SDF** & **Gp2 \textless{} Gp1** \\  & & & & & **Gp2: slice** & **MIC:** \\  & & & & & **Gp2: 3\%-_S. mutans_, _S. mutans_, _S.*_E. faecalis_; & **Gp1: SDF** & **3\%-_E. faecalis_; \\ [PERSON] et al., 2017 & In vitro & _S. mutans_, _E. faecalis_ & 1 day; MIC, MBC & **Gp2: NSF** & **Gp3: 3\%-_S. mutans_, _S.*_E. faecalis_; & **Gp3: PPF** & **Gp3: 3\%-_S. mutans_, _S.*_E. faecalis_; \\  & & & & & **Gp1: SDF** & **Gp3: 10\%-_S. mutans_, _S.*_E. faecalis_; \\  & & & & & **Gp1: SDF** & **CFU: Grp2: CHX** & **No significant difference** \\  & & & & & **Gp1: SDF** & **CFU: Grp3 \textless{} Gp2** \\  & & & & & **Gp2: SDF + KI** & **Gp1** \\  & & & & & **Gp3: K1** & **Gp1** \\  & & & & & **Gp1: SDF + NaF** & **CFU: Grp2 \textless{} Gp1** \textless{} Gp3** \\  & & & & & **Gp2: SDF** & **Gp4 \textless{} Gp3** \\  & & & & & **Gp3: NaF** & **CLSM: Grp2 \textgreater{} Gp1** \\  & & & & & **Gp4: Water** & \textgreater{} Gp3,Gp4** \\ [PERSON] et al., 2019 & In vitro; human dentin & _E. faecalis_ & 21 days; CLSM & **Gp1: SDF** & **Gp2: CHX** & **CLSM: Grp3 \textless{} Gp1** \\  & & & & & **Gp3: NaOCl** & **J** \textless{} Gp2** \\  & & & & & **Gp1**: SDF** & **Gp1,Grp3 \textless{} Gp2**, \\ [PERSON] et al., 2019 & In vitro & _S. mutans_ & 4 days: inhibition zone; 7 days: biofilm assay & **Gp3: AgNO3** & **Antibacterial activity:** **Gp1** \textgreater{} \\  & & & & & **Gp2** \\ \end{tabular}
\end{table} 
Table 1: Studies on the antibacterial effect of silver diamine fluoride (SDF).