## 1 Introduction
In this case, the plasma is produced by an electromagnetic wave that travels along the interface between the plasma and the dielectric [36]. Standardly, we used argon as a carrier gas for the plasma generation and the yeast treatment because it is much cheaper than helium and colder than common atmospheric pressure discharges in air such as DBDs, corona or glow discharges [34]. In the microwave discharge, the plasma has a higher electron temperature than plasma obtained by the indirect and high-frequency discharge. Due to the high temperature of the electrons, there is also a higher dissociation and ionization degree, which is reflected in a wide range of uses of this type of discharge including wound healing [30, 31, 32, 33], surface decontamination of fruits [34] or deposition of thin layers [35]. This paper focuses on the first use of this discharge in the yeast _Candia glabrata_ as a model microorganism. _Candida glabrata_ is classified as a nondimorphic yeast that exists as a small blastocoid. In fact, _Candida glabrata_ is the only species of the genus _Candida_ that does not form pseudohydphae at temperatures above 37 \({}^{\circ}\)C. A distinguishing feature between _Candida glabrata_ and better known and investigated _Candida albicans_ is its haploid genome (in contrast to the diploid genome of _Candida albicans_). Interestingly, _Candida glabrata_ is more genetically related to baker's yeast (_Saccharomyces cerevisiae_) than to _Candida albicans_ or _Candida parapsilosis_[37,38]. _Candida glabrata_ can be found in the human body as a part of its natural microflora, mainly in the gastrointestinal tract, mouth or genital area. _Candida glabrata_ is usually well controlled or harmless in healthy people. However, it may cause problems to people with a suppressed immune system. Particularly at risk are hospitalized patients, people with HIV, people being treated for cancer and people who have had organ transplants [39]. The danger of the infections caused by _Candida glabrata_ lies in its innate resistance to the azide antifungal therapy, which is very effective in treating infections caused by other _Candida_ species. _Candida glabrata_ retains many other virulence factors, such as the ability to adapt quickly to stressful conditions and the ability to secrete phospholipases, lipases and hemolysis, which contribute to an extreme aggression leading to a low therapeutic response and severe recurrent candidiasis. Among the most crucial virulence factors is the expression of the gene adhesin, thanks to which the organism can adhere to biotic and abiotic surfaces in microbial substrates. Adhesin expression is the mechanism by which _Candida glabrata_ produces fungal biofilms that have been shown to be more resistant to antifungals than planktonic cells. The ability to form biofilms is considered to be the most important virulence factor of _Candida glabrata_. Biofilms are known as the surface-associated communities of microorganisms embedded in the extracellular matrix that require significant antifungal therapy and host immune responses [40; 41]. Infections caused by the yeasts of the genus _Candida_ are called candidiasis. _Candida glabrata_ is currently ranked the second or third in the world as a cause of superficial (oral, esophageal, vaginal, urinary) or systemic candidiasis [40]. Based on these facts, there is an emergent necessity to find new nontraditional ways to inactivate this yeast.