# Smart Healthcare Applications over 5G Networks: A Systematic Review
## 1 Introduction  
Technological evolution has not only allowed intelligent systems' development in the manufacturing, transportation, and automation industries, but also in the medical industry, leading to an improvement in people's quality of life. On this specific topic, smart devices' use originated the concept of smart healthcare--healthcare based on technological support. The main applications of smart healthcare are remote monitoring, telemedicine, telesurgery, and mobile medical assistance [1]. The deployment of smart healthcare applications in recent years has been developed based on the use of 4G [1,2] technology, while also using resources from previous generations. However, these have not been able to meet real needs that the smart health field demands, due to technological restrictions such as: limited bandwidth, slow transfer speed, and high latency [2]. Although 4G has been used in Internet of Medical Things (IoMT) applications for connecting various physical devices, such as cell phones, physiological monitors, bodysensors, and wearable devices [3], it faces numerous challenges when the number of device connections increases. Therefore, to meet the demands of IoMT, a more evolved network than 4G is required in terms of speed, latency, support for simultaneously connected devices, and data storage capacity [2; 3]. To solve this problem, the 5G network presents itself as an excellent alternative thanks to its greater performance compared to the 4G network. With the use of 5G, the current limitations will be fully eliminated. High transmission speed, ultra-low latency, enhanced mobile broadband, and a network capacity superior to that of 4G will enable innovation in healthcare [2]. For example, with ultra-low-latency communication, an ambulance can support remote and diagnostic operations [4]. In addition, smart healthcare is expected to grow significantly by 12.5% by 2025 [5]. Fifth-generation technology in smart healthcare can not only be used for healthcare for sick people, but also facilitates preventive care [6]. At the same time, it has the ability to transfer and manage medical data in bulk, interactive video and real-time remote device control [7]. These data can be archived or transmitted between patients and medical professionals, so the technology can meet the demands of multiple consultations. Likewise, it will be possible to have immediate access from any place and at any moment to the patients' personalized medical data through digital networks [3]. For example, large X-ray (XR) image files, such as magnetic resonances, can be sent by patients to specialists for review [1; 6]. As 5G deployment advances, new studies are emerging in the medicine field, showing an increase in clinical cases covered by this technology. Through the application of telesurgery, teleconsultation, sanitary assistance, diagnosis and preventive care, platforms, systems, and apps have been created to facilitate healthcare. The existence of growth in the development of technological solutions also increases the existing scientific literature in this regard. For this reason, a systematic review analysis is required that allows interested developers and researchers to have a useful and understandable resource where they can learn about the progress of the solutions generated and the new challenges that must be faced. In this context, several authors have made reviews of the states of the art that provide multiple perspectives on the advancement of smart healthcare applications developed on the 5G network. The most significant works and the main differences between them and the work presented in this article are mentioned below. * [PERSON] et al. [8], in 2017, presented the challenges and difficulties that could hinder 5G development in the health sector. The authors mentioned the fact that 5G, in conjunction with IoT devices, big data, artificial intelligence (AI), and machine learning (ML), has the potential to transform health systems globally.