## 5 Future Perspective and Conclusions  
According to [PERSON] et al. [113], molecularly imprinted polymers have recently become a perfect option for the selective and sensitive detection of target molecules in complex matrices where other structurally identical and related chemicals may coexist. Although MIPs exhibit the inherent qualities of polymers, such as stability, resilience, and ease/low cost of synthesis, when nanoparticles are introduced into their polymeric structure, certain of their characteristics can be increased, and new functions can be produced. The large number of nanoparticles accessible greatly increases the chances of finding the right nanostructured MIP design for any analytical challenge. Furthermore, depending on the synthesis method employed, different structures (such as monolithic solids or MIPs micro/nanoparticles) can be created.  
Conventional SPE methods are typically burdened by the required additional solvents, possible evaporation and reconstitution steps, and additional time involved. Recently, in an attempt to address these limitations, a molecular imprinted solid-phase extraction has been demonstrated to be a reliable and cost-effective technique for the selective isolation and concentration of a wide range of analytes and sample matrices, and offers many improvements over traditional techniques, although there have been some limitations to the methodology, such as the amount of time required to perform any analysis. As there are already multiple measures to prevent or even minimize these limitations, MISPE is regarded as a robust analytical tool. It is worth noting that, while MIPs are difficult to optimize, their versatility and sensitivity make them ideal for identification and purification analysis.  
There are many applications of MIPs in the various scientific fields. We are currently concentrating on their synthesis and characterization. Presently, the preparation of MIPs has been validated by a wide range of scientific experts that are interested in the development of MIPs that can be adapted into microextraction and solvent-free techniques, which bodes well for the future of this field of study. MIPs can be incorporated into contemporary sample preparation microextraction techniques without affecting their inherent selectivity and stability by making clever (and relatively simple) changes to the polymerization procedures. The developed methods for creating MIP-based microextraction devices are reliable and straightforward, and they can be carried out in any laboratory with the necessary equipment.  
S.K. and N.M.N. performed the material preparation, data collection, and analysis. S.K. contributed to the study conception and design. S.K. and N.Y. wrote the first draft of the manuscript. S.K., S.M.M.F, N.Y., W.N.W.I and N.S.M.H. read and approved the final manuscript. All authors have read and agreed to the published version of the manuscript.  
This research was funded by the Ministry of Higher Education, Malaysia under Fundamental Research Grant Scheme (FRGS) through (FRGS/1/2018/STC01/UPM/02/17) with the vote number of 5540122 and Universiti Putra Malaysia (GP-IPM/2015/9456000). This research was funded by the Ministry of Higher Education, Malaysia under Fundamental Research Grant Scheme (FRGS) through (FRGS/1/2018/STG01/UPM/02/17) with the vote number of 5540122 and Universiti Putra Malaysia (GP-IPM/2015/9456000).  
Not applicable.  
All data generated or analyzed during this study are included in this published article.  
The authors declare no competing interests.