# Machine Learning and rs-fMRI to Identify Potential Brain Regions Associated with Autism Severity
## 2 Methodology
### Materials
#### 2.1.1 Automated Anatomical Labeling (AAL)  
An atlas is a brain mapping that allows us to evaluate brain activity through its regions. We used the AAL atlas [34] available at ABIDE, as it is the most used atlas in the literature for ASD classification using fMRI and ML [21], reaching meaningful outcomes in [18; 20; 35; 36; 37].  
In its third version, AAL segments the human brain into 116 ROIs. A detailed explanation of these regions can be seen in [34]. Table 1 presents the AAL's labels.  
\begin{table}
\begin{tabular}{c c c c c c} \hline \hline
**ID** & **Label Name** & **ID** & **Label Name** & **ID** & **Label Name** \\ \hline
**0** & Precentral.L & **39** & ParaHippocampal.R & **78** & Heschl.L \\ \hline
**1** & Precentral.R & **40** & Amygdala.L & **79** & Heschl.R \\ \hline
**2** & Frontal.S.L & **41** & Amygdala.R & **80** & Temporal.S.L \\ \hline
**3** & Frontal.S.R & **42** & Calcarine.L & **81** & Temporal.S.R \\ \hline
**4** & Frontal.S.Orb.L & **43** & Calcarine.R & **82** & Temporal.Pole.S.L \\ \hline
**5** & Frontal.S.Orb.R & **44** & Cureus.L & **83** & Temporal.Pole.S.R \\ \hline
**6** & Frontal.Mid.L & **45** & Cureus.R & **84** & Temporal.Mid.L \\ \hline
**7** & Frontal.Mid.R & **46** & Lingual.L & **85** & Temporal.Mid.R \\ \hline
**8** & Frontal.Mid.Orb.L & **47** & Lingual.R & **86** & Temporal.Pole.Mid.L \\ \hline
**9** & Frontal.Mid.Orb.R & **48** & Occipital.S.L & **87** & Temporal.Pole.Mid.R \\ \hline
**10** & Frontal.Inf.Oper.L & **49** & Occipital.S.R & **88** & Temporal.Inf.L \\ \hline
**11** & Frontal.Inf.Oper.R & **50** & Occipital.Mid.L & **89** & Temporal.Inf.R \\ \hline
**12** & Frontal.Inf.Tri.L & **51** & Occipital.Mid.R & **90** & Cerebelum.Crus1.L \\ \hline
**13** & Frontal.Inf.Tri.R & **52** & Occipital.Inf.L & **91** & Cerebelum.Crus1.R \\ \hline
**14** & Frontal.Inf.Orb.L & **53** & Occipital.Inf.R & **92** & Cerebelum.Crus2.L \\ \hline
**15** & Frontal.Inf.Orb.R & **54** & Fusiform.L & **93** & Cerebelum.Crus2.R \\ \hline
**16** & Rolandic.Oper.L & **55** & Fusiform.R & **94** & Cerebelum.3.L \\ \hline
**17** & Rolandic.Oper.R & **56** & Postcentral.L & **95** & Cerebelum.3.R \\ \hline
**18** & Sp.Motor.Area.L & **57** & Postcentral.R & **96** & Cerebelum.4.5.L \\ \hline
**19** & Sp.Motor.Area.R & **58** & Parietal.S.L & **97** & Cerebelum.4.5.R \\ \hline
**20** & Olfactory.L & **59** & Parietal.S.R & **98** & Cerebelum.6.L \\ \hline
**21** & Olfactory.R & **60** & Parietal.Inf.L & **99** & Cerebelum.6.R \\ \hline
**22** & Frontal.S.Medial.L & **61** & Parietal.Inf.R & **100** & Cerebelum.7b.L \\ \hline
**23** & Frontal.S.Medial.R & **62** & SraMarginal.L & **101** & Cerebelum.7b.R \\ \hline
**24** & Frontal.Med.Orb.L & **63** & SraMarginal.R & **102** & Cerebelum.8.L \\ \hline
**25** & Frontal.Med.Orb.R & **64** & Angular.L & **103** & Cerebelum.8.R \\ \hline
**26** & Rectus.L & **65** & Angular.R & **104** & Cerebelum.9.L \\ \hline
**27** & Rectus.R & **66** & Precuneus.L & **105** & Cerebelum.9.R \\ \hline
**28** & Insula.L & **67** & Precuneus.R & **106** & Cerebelum.10.L \\ \hline
**29** & Insula.R & **68** & Parcentral.Lobule.L & **107** & Cerebelum.10.R \\ \hline
**30** & Cingulum.Ant.L & **69** & Parcentral.Lobule.R & **108** & Vermis.1.2 \\ \hline
**31** & Cingulum.Ant.R & **70** & Caudate.L & **109** & Vermis.3 \\ \hline
**32** & Cingulum.Mid.L & **71** & Caudate.R & **110** & Vermis.4.5 \\ \hline
**33** & Cingulum.Mid.R & **72** & Putamen.L & **111** & Vermis.6 \\ \hline
**34** & Cingulum.Post.L & **73** & Putamen.R & **112** & Vermis.7 \\ \hline
**35** & Cingulum.Post.R & **74** & Pallidum.L & **113** & Vermis.8 \\ \hline
**36** & Hippocampus.L & **75** & Pallidum.R & **114** & Vermis.9 \\ \hline
**37** & Hippocampus.R & **76** & Thalamus.L & **115** & Vermis.10 \\ \hline
**38** & ParaHippocampapal.L & **77** & Thalamus.R & \\ \hline \hline \end{tabular}
\end{table}
Table 1: Automated anatomical labeling (ID and name).