###### Abstract  
This study presents a design and evaluation of a mock circulatory platform, which can reproduce blood pressure and its waveforms to provide palpation experience based on the human cardiovascular physiology. To reproduce the human cardiovascular behavior, especially the blood pressure, the proposed platform includes three major modules: heart, artery and reservoir modules. The heart module reproduces source pressure exerted on the whole system with a controlled time-profile. The artery module consists of a resistance valve to adjust the open area of the vessel and a compliance chamber adjusting the wall stiffness of the ascending aorta. The designed platform was cross validated by comparing the theory with a lumped model, i.e., the windkessel model, the measurements from the mock circulatory platform and the real human body data. As a result, the ventricular and aortic pressure waveforms measured from the designed platform were well matched with those of the actual human body. Parametric studies regarding peripheral resistance and aortic compliance were done for the detailed correlation analysis between human cardiovascular physiology and blood pressure. Since the proposed platform is based on the actual cardiovascular physiology, adjusting the structural parameters of the components can reproduce realistic blood pressure waveforms in a controllable manner. This platform is applicable to blood pressure measurement sensor calibration, palpation training, and haptic feedback. cardiovascular; blood pressure; waveform; physiology; circulatory platform; windkessel model; fluid-electric analogy; palpation 2020 10 5433 10.3390/app10165433 10.3390/app10165433 10.  
anatomy of the patient's muscles, bones, and blood vessels [1; 2]. Haptic sensation plays an important role in allowing most surgeons to avoid damage to healthy tissue and unintentional perforation/rupture of blood vessels. For this reason, palpation is an important procedure done before an open surgical process for locating hidden blood vessels beneath tissue by detecting pulses and distinguishing arteries from veins [3]. This procedure requires advanced training experience either on a number of human bodies or using the haptic palpation simulator, which is more cost-effective as long as it gives accurate pulse signatures matched to the human bodies. To date, most haptic palpation simulators have focused on developing portable simulators that deliver artificially created haptic feelings in conjunction with virtual reality, rather than developing devices that reflect human physiology for technical difficulties and costs [4; 5; 6]. Reproduction of the blood pressure waveform is important for palpation training. To be used in medical practice or diagnosis, it is necessary to reproduce the blood pressure waveforms of femoral, radial, and abdominal arteries [7; 8]. For palpation training, a study was performed to implement a blood pressure waveform according to the patient's age through a cam profile and delivering it to a hand phantom with a pneumatic actuator [9]. However, a method transmitting an artificially generated haptic sense based on electric actuators or motor-based multi-degree-of-freedom force feedback devices is limited in training a real feeling to the clinician. In addition, these methods have limitations that cannot provide in-depth training associated with the blood pressure waveforms based on the physiological characteristics of the human body. To overcome these limitations, this study proposes a mock circulatory platform simulating cardiovascular physiology of the human body for advanced haptic palpation training of arteries. This mock circulatory simulator aims not only to reproduce blood pressure waveforms in blood vessels identically, but also to realize the physiology of blood circulation in the human body for further in-depth studies on the cardiovascular physiology. Previous studies on cardiovascular simulators have been intended mainly for endurance testing of an artificial heart, artificial valve, or stent [10; 11].