## 3 Results
The aspects recorded at seven days capture the biochemical events when the cascade of reaction of the inflammatory response, allergen type reaction, continues with the particularities corresponding to the stage of intercellular interaction upon material type, a fact iterated by the obtained values statistically interpreted as MTA 178, 9 IU/L, Bioaggregate 181.9 IU/L, Sealapex 167.3 IU/L. Through the above-mentioned procedures, we tried to validate the information, using rehabilitation treatments methodology, based on various prosthetic devices and all kinds of possible, biocompatible, materials used in prosthesis technology, with regard to the electronic-microscopically studied root filling materials, in order to be used in dental practice, especially in the prosthetic stability rehabilitation accompanied by aesthetic response of periodontal tissue support therapy. \begin{table}
\begin{tabular}{c c c c c c c c c} \hline \hline \multirow{2}{*}{**Rabit No.**} & \multirow{2}{*}{**Control Rabbit**} & \multicolumn{6}{c}{**Implanted Material**} \\ \cline{3-8}  & & & **Sealapex** & **MTA** & **BioAggregate** \\ \hline
1 & & 162.8 & 164.2 & 164.8 \\
2 & 163.6 & 163.4 & 165.4 & 164.1 \\
3 & & 165.2 & 167.5 & 166.4 \\ \hline \hline \end{tabular}
\end{table} 
Table 3: Alkaline phosphatase values at 30 days postoperatively (IU/L). \begin{table}
\begin{tabular}{c c c c c c c c c c} \hline \hline \multirow{2}{*}{**Implanted Material**} & \multirow{2}{*}{**Evaluation**} & \multirow{2}{*}{**Mean**} & \multicolumn{3}{c}{**Average**} & \multirow{2}{*}{**Std Dev.**} & \multirow{2}{*}{**Std Er.**} & \multirow{2}{*}{**Min.**} & \multirow{2}{*}{**Max.**} & \multirow{2}{*}{**Median**} \\ \cline{3-8}  & & & & **\(-\)95\%** & & & & & \\ \hline Sealapex & 7 days & 167.25 & 165.24 & 169.26 & 1.92 & 0.78 & 164.30 & 169.10 & 167.85 \\ \hline Sealapex & 30 days & 181.18 & 171.41 & 190.94 & 6.14 & 3.07 & 173.90 & 188.90 & 180.95 \\ \hline Sealapex & 60 days & 163.10 & 159.29 & 166.91 & 0.42 & 0.30 & 162.80 & 163.40 & 163.10 \\ \hline MTA & 7 days & 178.95 & 177.13 & 180.77 & 1.73 & 0.71 & 176.50 & 181.30 & 178.95 \\ \hline MTA & 30 days & 193.80 & 186.97 & 200.63 & 4.29 & 2.15 & 189.80 & 198.40 & 193.50 \\ \hline MTA & 60 days & 164.80 & 157.18 & 172.42 & 0.85 & 0.60 & 164.20 & 165.40 & 164.80 \\ \hline BioAggregate & 7 days & 181.93 & 180.22 & 183.65 & 1.63 & 0.67 & 179.80 & 183.80 & 182.35 \\ \hline BioAggregate & 30 days & 196.15 & 191.94 & 200.36 & 2.65 & 1.32 & 193.10 & 199.40 & 196.05 \\ \hline BioAggregate & 60 days & 164.45 & 160.00 & 168.90 & 0.49 & 0.35 & 164.10 & 164.80 & 164.45 \\ \hline control & & 163.60 & & & & & & 163.60 & 163.60 & 163.60 \\ \hline \hline \end{tabular}
\end{table} 
Table 4: Statistical indicators of alkaline phosphatase in the study group according to the biomaterial used and time of determination. Therefore, we applied endodontic treatments to the patients using the mentioned materials, followed by prosthetic restorations, special fixed restorations: composite crowns in the lateral arch, premolar area, in ten women (35.71%) and seventeen men (60.71%) as well as ceramic restorations placed in the frontal area in two women (7.14%) and five men (17.85%). In the posterior arch area, metal ceramic prosthetic devices were applied bilaterally in seven women (28%), and in the frontal area for two women (7.14%), while for men there were six (21.42%) metal-ceramic prosthetic devices in the frontal area and four (14.28%) prosthetic appliances in the posterior area. Periodonal cure has been used in twelve cases (42.85%) through etiological curettage, surfacing also followed by gingivectomy interventions and subsequent occlusal interventions, orthodontic treatments, and mouthguard appliances. Considering the aspects revealed by the individual pathologies, it is absolutely necessary to take into account the more complex situations that would require a special approach.