###### Abstract
However, dietary habits do not seem to fully explain the development of micronutrient deficiencies in obesity since the condition may not be simply alleviated by providing an adequate concentration of deficient micronutrients to patients who are obese [13]. At present, the cause of micronutrient deficiencies in the population with obesity remains poorly understood. Nevertheless, given that obesity co-occurs not only with micronutrient deficiencies but also with the dysbiosis of intestinal microbiota [14], in recent years, authors started to link both these conditions and give more interest to the role of microbiota in the nutritional status of individuals with obesity [15]. Indeed, microorganisms may interact with micronutrients in various ways, including modulation of their passage through the intestinal epithelium [16]. Therefore, the hypothesis that the microbiota plays a role in the nutritional status of the organism seems justified. However, the interplay between microbiota, micronutrients, and obesity has not been reviewed in detail so far. In particular, to our knowledge, currently, there is no work available that has gathered scientific evidence on the effects of the supplementation of deficient micronutrients in people with obesity and related disorders at adequate doses and discussed whether microbiota interventions could help to replenish the micronutrient status of this population group. Nevertheless, given the pressing need for the development of effective obesity treatment approaches, such works are much needed. This work aimed to evaluate the role of micronutrients in obesity and review factors that may govern the nutritional status of the body, with a special focus on microbiota. The aim was achieved through gathering the strongest and most recent research evidence on the following:  
1. Effects of micronutrient-deficient diet on obesity;
2. Effects of obesity on micronutrient deficiency;
3. Effects of micronutrient supplementation on weight management and metabolic health in obesity; \begin{table}
\begin{tabular}{c c c c} \hline
**Miconutrient** & **Via 2012 [3]** & **[PERSON] and DiBaise, 2017 \({}^{\star}\)** [4]** & **[PERSON] et al., 2022 \({}^{\star}\)** [5]** \\ \hline Vitamin A & 17 & 0–17 & - \\ Vitamin D & 80–90 & 22–80 & 20–98 \\ Vitamin C & 35–35 & - & - \\ Vitamin B1 & 15–29 & - & - \\ Vitamin B6 & 0–11 & - & - \\ Vitamin B9 & 3–4 & 0–32 & 0–63 \\ Vitamin B12 & 3–8 & 0–12 & 5–34 \\ Magnesium & - & 0–35 & - \\ Calcium & - & 0–14 & - \\ Iron & - & 1–9 & 2–29 \\ Selenium & 58 & 3 & - \\ Zinc & 14–30 & 0–3 & - \\ \hline \end{tabular} \({}^{\star}\)In people with morbid obesity prior to bariatric surgery.  
\end{table} 
Table 1: Prevalence (%) of micronutrient deficiencies in people with obesity quoted in selected reviews. Mechanisms used by microorganisms to impact the bioavailability of micronutrients;
5. Effects of the interventions into microbiota on the micronutrient status of humans. The scientific evidence from both human and knowledge-wise complementary animal studies was gathered. This work was concluded with a highlight of existing knowledge gaps that, when filled, could contribute to the development of effective obesity treatments.