# Challenge of Utilization Vegetal Extracts as Natural Plant Protection Products
## 3 Next Level: Natural Plant Protection Products (Biopesticides)  
Today, the concern for people's life quality has become more obvious by ensuring the protection of the environment and food safety. Food quality is closely related to raw material production conditions. Vegetable crops, seed production and preservation are influenced by the quality of pest control products and management of weeds as well as parasitic crops. A few regulations were permitted to reduce the usage of synthetic chemical plant protection products in agriculture where it was possible [20]. At the same time, it was expanded the phenomenon of resistance of the insects and harmful organisms to the action of synthetic chemical plant protection products dispersed on vegetal plants as a result of repeated use and increased doses [21]. In this context, new concepts appear and develop, such as the nano-biopesticides [22; 23; 24] and ecological organic agriculture. The concept of ecological organic agriculture does not accept the use of chemical synthesis compounds in order to protect, stimulate the growth or preservation of plants, fruits, and seeds [1; 25], and thus a new category of compounds, natural plant protection products, appeared as a challenging alternative. Natural plant protection products (biopesticides) are natural compounds obtained from the mineral, plant, or animal kingdom, including microorganisms, by various methods of extraction of active compounds or classes of active compounds/ingredients with beneficial effects in pest control through various mechanisms [13; 26; 27; 28]. The natural plant protection products are considered the third-generation of chemical plant protection products (pesticides) that are rapidly gaining popularity. Starting with the 19 th century, agriculture begun to use natural insecticides such as pyrethrum and rotenone, derived from chrysanthemum flower powders and _Derris_ roots [20]. A wide range of microbial products derived from microorganisms and other natural sources have been added to its [13; 15; 21; 29; 30]. The natural compounds of the general category of biopesticides may belong to the next subclasses: biofungicides (e.g., _Trichoderma_ spp. ), bioherbicides (_Plytophthora_ spp. ), bioinsecticides (spores forming bacteria, _Bacillus thuringiensis_ and _B. popilliae_, _Actinomycetes_), entomopathogenic fungus (_Beauveria bassiana_), microscopic roundworms (Entomopathogenic nematodes) [31], spinosad (_Saccharomyces spinosa_), insect hormones, and insect growth regulators [3; 17; 29; 14]. Among the natural plant protection products, bioinsecticides used in the protection of crops and seeds in storage conditions and the management of weed control are of particular interest. There are known situations when it was applied different volatile oils obtained from different plants for their bioinsecticide effect, although the mechanism of action is insufficiently known [16; 21; 32; 33]. In a recent review, [PERSON] and [PERSON] (2014) make a remarkable systematization for an impressive number of plants (227) belonging of many botanical species (259) from which volatile oils with a very complex chemical composition were obtained (i.e., spathulenol (8.6%), cryophyllene oxide (7.5-10.6%), cis-3-hexen-1-ol (11.3%), 1-hexanol (5.8%), \(\beta\)-caryophyllene (9.7%), \(\gamma\)-cadinene (5.0%)), which showed insecticidal activity [16]. The classes of biologically active compounds in most essential vegetable oils are terpenes and terpenoids (-25,000 types, 55%), alkaloids (-12,000 types, 27%), and phenolic compounds (-8000 types, 18%) which can be framed into two major classes: phytoalaxins which are compounds that are synthesized _de novo_ (as opposed to be released by, for example, hydrolytic activity) and phytoanticipins which are pre-formed infectious inhibitors [32]. The authors also systematized the results of some studies performed for determination of the essential vegetal oils' effect on insects.