## 2 Materials and Methods
### Interventions  
Two experienced physiotherapists conducted the interventions in the center's therapeutic gym. For both groups, the protocol lasted ten weeks, with three non-consecutive sessions per week (total of 30 sessions), and participants were considered adherent if they attended \(\geq\)20 sessions (2/3 of the total) [33]. The exercise intensity ranged from light to moderate according to a perceived exertion scale of 0-10 points, with an equivalent weekly volume of 150 min across groups [34]. Attendance, adverse events, and overall health status were monitored throughout the experimental period. The interventions for each group are described below. Control group: This group followed a protocol consisting of the following phases: (i) physical agents (10 min): simultaneous use of electotherapy (TENS) and superficial thermotherapy (hot packs); (ii) warm-up (5 min): free joint movements; (iii) exercise blocks (50 min): aerobic exercises (e.g., stationary cycling and treadmill walking), muscle strengthening for limbs/trunk (e.g., elastic bands, dumbbells, and bodyweight exercises), postural balance (e.g., unstable surfaces, single-leg stance, tandem and obstacle walking), and general flexibility for limbs/trunk; (iv) cool-down (5 min): breathing exercises; and (v) physical agents (10 min): simultaneous use of electotherapy (TENS) and superficial thermotherapy (hot packs). The specific exercises of each block (aerobic, strength, balance, and flexibility) were alternated in each session and indicated with an individualized approach in series and repetitions according to the tolerance of each participant, considering an approximate rest period of two minutes between blocks. The Supplementary Material in Table S1 provides further description of the conventional exercises incorporated into the protocol. Experimental group: This group performed the same phases as the CG, but the exercise block phase lasted 30 min, which reduced the number of sets and repetitions. After this phase, 20 min of AVGs was added, thus ensuring an equivalent exercise time in both groups (50 min per session). The AVGs were organized into three sets (one for each weekly session). They included a series of analytical exercises, yoga postures, and playful physical activities from the game Ring Fit Adventure (Nintendo Switch(r)). Sixteen exercise games were selected according to the clinical characteristics of the population, which were balanced to cover the basic components of functional fitness (aerobic endurance, strength, balance, and flexibility). Exercises, such as \"Dorsal rotation\" and \"Rotation with inclination\", involve active trunk mobility, the first one in an upright posture and the second one combined with a semi-squat and pauses at the point of maximum rotation. In \"Knee raises\", participants alternately lift their knees, integrating arm flexion and extension, while in \"Squats\", controlled squats with pauses in semi-flexion are performed. \"Lunge with rotation\" requires a forward lunge step, rotating the torso towards the leading leg. \"Lateral inclination\" involves controlled trunk inclinations, while \"Squats with extension\" combines squats with external foot rotation and pauses in semi-flexion. Additionally, three yoga-inspired activities that demand alignment and stability are included: \"The warrior\", \"The chair\", and \"Crescent moon\". Other activities include dynamic games requiring precision, postural control, and strength. In \"Equilibrium\", the participant must move swiftly to avoid obstacles and collect coins. \"Moto aduductors\" is performed seated and requires controlling the movement of a cart by applying pressure on the exercise ring between the knees. \"Trunk swinging\" requires quick, coordinated trunk movements with raised arms. Finally, three running games were included, \"Running path\", \"Monster's lair\",and \"Jogging bridge\", which demand continuous walking or jogging, pace adjustments, and coordinated activities to overcome obstacles in dynamic environments.