## 6 Conclusions  
This study has conducted an in-depth geostatistical analysis of seismic activity in the Red Sea region, covering the period from 1997 to 2020. Utilizing a GIS framework and a suite of spatial analytic methods--including ANN, QCA, Global Moran's I, Local Moran's I, and the Getis-Ord \(Gi\)* statistic--we have effectively unraveled the complex temporal and spatial dynamics of seismic events in this tectonically active area. Our findings have outlined distinct seismic patterns along the Central Red Sea axis, which are indicative of the rifting dynamics between the African and Arabian plates. The application of ANN and QCA has shed light on the general distribution and density of seismic occurrences, while GMI and LMI have been instrumental in highlighting areas of spatial clustering and dispersion. Notably, LMI has revealed significant clustering of seismic activities across different magnitudes, suggesting a nuanced relationship between earthquake magnitudes and the region's dynamic tectonic setting. Through LISA analysis for various periods, we have demonstrated consistent spatial autocorrelation in seismic activities. The identification of high-high clusters along the central rift axis underscores zones of elevated seismicity, while low-low clusters indicate areas of relative tectonic stability. These findings, corroborated by LISA significance maps, align well with the known tectonic divergence in the Red Sea. Moreover, the analysis of Getis-Ord \(Gi\)* statistic maps has confirmed persistent seismic clustering along the central rift, indicative of active tectonic rifting. The temporal consistency of these patterns underscores the ongoing nature of the rifting process, which is integral to the formation of new oceanic crust in the Red Sea. Kernel Density Estimator analyses across various moment magnitude ranges have revealed concentrations of seismic activity in key areas such as the Gulfs of Aqaba and Suez, as well as the Central and Northern Red Sea. This spatial distribution correlates with known geological features and fault lines. Importantly, higher magnitude events tend to localize in areas of greater tectonic stress, highlighting the complex interplay between seismic events and the underlying geological framework. Our comprehensive analysis revealed pronounced seismic patterns along the Central Red Sea axis, correlating with tectonic rifting between the African and Arabian plates. The spatial analysis techniques employed delineated areas of heightened seismic activity and zones of relative tectonic stability. Notably, the Local Moran's I highlighted significant clustering of seismic activities, with variations in intensity across magnitudes. The Getis-Ord \(Gi\)* statistic maps confirmed persistent seismic hotspots along the central rift, indicative of active tectonic processes. Kernel Density Estimator analyses revealed a concentration of seismic activity in key geological areas, with higher magnitude events localizing in regions of greater tectonic stress. These findings underscore the dynamic tectonic setting of the Red Sea and demonstrate the utility of geostatistical techniques in seismic analysis. Conceptualization, methodology, software development, validation, data collection, analysis and writing: S.S.R.M. ; Conceptualization, review and editing: M.H.Y. and M.M. ; Data collection, analysis A.M.F. and B.E. All authors have read and agreed to the published version of the manuscript. This research was funded by the Deputyship for Research and Innovation, \"Ministry of Education\" in Saudi Arabia (IFKSUOR3-093-2). Not applicable. The data presented in this study are available upon reasonable request from the first author. The data are not publicly available due to official regulations. The authors would like to express their sincere gratitude to the Egyptian National Seismic Network (ENSN) at the National Research Institute of Astronomy and Geophysics (NRIAG) for their invaluable assistance with this research.