An in vitro study was performed on a PC12 cell line treated with hydrogen peroxide to induce oxidative stress in order to evaluate the neuroprotective effect of strawberries, a fruit rich in anthocyanins, whose antioxidant capacity has also been compared to that of bananas and oranges. Strawberries showed the highest neuroprotective activity, most likely due to the high anthocyanin content [27]. Another study evaluated the antioxidant activity of the frozen pulp of acai berries in the brains of rats given hydrogen peroxide [28]. Pre-treatment with acai considerably reduced the destruction of lipids and proteins induced by hydrogen peroxide. Additionally, in the presence of acai, the activity of antioxidant enzymes was maintained at a basal level [28; 29]. One research study evaluated the protective effects of an ethanoic extract of mulberry fruit (_Morus alba L._) against chemically induced neurotoxicity (6-hydroxyopamine and 1-methyl-4-phenylpyridinium producing changes corresponding to [PERSON]'s disease) [30]. Pre-treatment with mulberry extract of the SH-SY5Y cell line (derived from human neuroblastoma) or of a primary culture of murine dopaminergic neurons, protected cells from the effects of neurotoxins by its antioxidant and antiapoptotic action [30; 31]. An additional study looked at the neuroprotective effects of anthocyanins extracted from black soybean based on a model of \(\beta\)-amyloid-induced neurodegeneration [32]. The extract was used to treat an HT22 cell line and was also injected intra-cerebventrally into adult rats to induce neurotoxicity. Anthocyanin treatment performed for 12 h led to the restoration of cell viability, normalized membrane potentials and Ca\({}^{2+}\) levels, and decreased neuronal death. Furthermore, anthocyanins reversed the effects of \(\beta\)-amyloid on the protein expression of mitochondrial apoptotic pathways, such as cytochrome-C, and Alzheimer's disease-specific markers, such as tau proteins and \(\beta\)-secretase-1, a precursor of \(\beta\)-amyloid [32]. Other studies have shown that supplementing a diet with strawberries or blueberries fruits rich in anthocyanins, led to a reversal of motor and cognitive disabilities specific to old age in rats [33]. Therefore, anthocyanins are a class of compounds with pleiotropic activity, and their ability to modulate several aspects of the installation and progression of neurodegenerative diseases makes them promising candidates in the auxiliary treatment of these pathologies [34]. Among the processes in which they occur are oxidative processes, calcium and protein homeostasis, neuro-inflammation, and apoptotic neural pathways. Moreover, the fact that they are frequently found in a normal diet confirms that their use is safe. However, in order to confirm the evidence obtained on cell lines and animal models, it is necessary to design in vivo studies to be performed on humans; however, currently their number is low [35]. Along with polyphenols, the following compounds are also recognized for their significant antioxidant action: terpen (carotenoids), phytosterols, sulfur compounds, and a series of vitamins (E, C). terpenes are carotenoids, compounds that capture singlet oxygen (\({}^{1}\)O\({}_{2}\)) in the human body [36; 37]. Carotenes take over the extra electron of free radicals and turn into less-reactive radicals that gradually release energy stored in the form of heat with the restoration of carotenes [38]. Phytosterols inhibit lipid peroxidation and superoxide anion radical formation [39]. Sulfur compounds with antioxidant actions include glucosinolates, indoles, and allyl sulfides [40]. Vitamin C is known for its ability to reduce some reactive oxygen species, such as peroxides and superoxide anion radicals [41]. Based on these considerations, attention has been focused on researching those plant products that contain these types of active principles and that by association can induce a clearly superior antioxidant action [42; 43; 44; 45; 46].