## 4 Discussion  
A large number of works have been carried out in the past decades to identify genetic markers for both endometriosis and RPL [25; 26; 27; 28; 29; 30; 31; 32; 33]. However, a trustworthy molecular marker having significant prognostic value has not yet been determined. Moreover, the lack of potential drug targets is also one of the probable causes for several unsuccessful \begin{table}
\begin{tabular}{c c c c c c c c c c} \hline \hline \multirow{2}{*}{**Name**} & \multirow{2}{*}{**Description**} & \multicolumn{2}{c}{**Average**} & \multirow{2}{*}{**Betweenness**} & \multirow{2}{*}{**Cloneness**} & \multirow{2}{*}{**Neighborhood**} & \multirow{2}{*}{**Node**} & \multirow{2}{*}{**Coenes**} & \multirow{2}{*}{**Genes**} & \multirow{2}{*}{**Coenes**} & \multirow{2}{*}{**Size**} & \multirow{2}{*}{**Coenes**} & \multirow{2}{*}{**Adjusted**} \\  & & **Path Length** & & & & & & & \\ \hline \multirow{4}{*}{31323} & regulation of the & & & & & & & & \\  & cellular & & & & & & & & \\  & metabolic & & & & & & & & \\  & process & & & & & & & & \\ \hline
23052 & signaling & 2.625 & 0.012372 & 0.380952 & 5.666667 & 12 & 36 & 0.00789 \\ \hline \multirow{4}{*}{32502} & developmental & 2.858824 & 0.112328 & 0.349794 & 7 & 11.6619 & 34 & 0.0216 \\ \hline \multirow{4}{*}{7275} & multicellular & & & & & & & \\  & organism & & & & & & & \\  & development & & & & & & & \\ \hline \multirow{4}{*}{10468} & regulation of & & & & & & & & \\  & gene expression & & & & & & & \\  & & & & & & & & \\ \hline \multirow{4}{*}{48856} & anatomical & & & & & & & & \\  & structure & & & & & & & & \\  & development & & & & & & & \\ \hline \multirow{4}{*}{16043} & cellular & & & & & & & & \\  & component & & & & & & & \\  & organization & & & & & & & & \\ \hline \multirow{4}{*}{48731} & system & & & & & & & & \\  & development & & & & & & & & \\ \hline \multirow{2}{*}{23033} & signaling & & & & & & & & \\  & pathway & & & & & & & \\ \hline \multirow{4}{*}{48869} & cellular & & & & & & & & \\  & developmental & & & & & & & \\  & process & & & & & & & \\ \hline \multirow{4}{*}{48523} & negative & & & & & & & & \\  & regulation of & & & & & & & \\  & cellular process & & & & & & & \\ \hline \multirow{4}{*}{30154} & cell & & & & & & & & \\  & differentiation & & & & & & & \\ \hline \multirow{4}{*}{48513} & organ & & & & & & & & \\  & development & & & & & & & \\ \hline \multirow{4}{*}{7166} & cell surface & & & & & & & & \\  & receptor linked & & & & & & & \\  & signaling & & & & & & & \\  & pathway & & & & & & & \\ \hline \multirow{4}{*}{51239} & regulation of the & & & & & & & & \\  & multicellular & & & & & & & \\  & organism & & & & & & & \\  & process & & & & & & & \\ \hline \multirow{4}{*}{35466} & regulation of & & & & & & & & \\  & signaling & & & & & & & \\  & pathway & & & & & & & \\ \hline \hline \end{tabular}
\end{table} 
Table 4: _Cont._attempts to ameliorate the diseases. Therefore, there is an urgent need for the identification of potential biomarkers for the two diseases. This study is one of the pioneers in finding a common potential biomarker for the two diseases for successful diagnostic purposes and for effective drug delivery systems. The literature survey provided epidemiological evidence to establish a probable link between endometriosis and RPL [34]. A recent investigation by [PERSON] et al. demonstrated an increased rate of spontaneous miscarriages in endometriosis-affected females [35]. Another interesting study in 2017 claimed mild endometriosis to be a potential risk for miscarriages [36]. Later in 2019, a study claimed that endometriosis affected the efficacy of assisted reproductive technology by increasing the risk of miscarriage [37]. More recently, [PERSON] et al. identified the NOLC1 gene as the most common gene in the phase I and II endometriosis and affects menstruation, while in phases III and IV, the genes _CDKN1B_, _DLD_, _ELOVL5_, _H2 AFZ_, _IDI1_, _ME1_, _MTHFD2_, _NOLC1_, and _SOD1_ play a major role.