## 2 Triterpenoids
### 8,9-ene-triterpenoids
#### 2.2.3 C27 Triterpenoids
\begin{table}
\begin{tabular}{c c c c c} \hline \hline \begin{tabular}{c} **No.** \\ \end{tabular} & \begin{tabular}{c} **Trivial Names** \\ \end{tabular} & \begin{tabular}{c} **Biactivities (IC\({}_{\text{sp}}\)/MIC or ED\({}_{\text{sp}}\))** \\ \end{tabular} & \
\begin{tabular}{c} **Sources** \\ _Ganoderma Species_ \\ \end{tabular} &
\begin{tabular}{c} **References** \\ \end{tabular} \\ \hline
**364.** & 4,414–Trimethyl-3,7-dioxo-5a- \\  & chol-8-en-24-oic acid &
\begin{tabular}{c} Moderate cytotoxicity against \\ HeLa cervical cells (48.0 uM) \\ \end{tabular} & \(G\). _lucidum_ & [215] \\ \hline
**365.** &
\begin{tabular}{c} Cytotoxicity against HL-60 \\ (645 uM), HepG2,25 (1.66 \(\times\) 10\({}^{-1}\) uM), \\ HepG 2,25 (1.66 \(\times\) 10\({}^{-1}\) uM), \\ HepG 1,20 \(\times\) 10\({}^{-2}\) uM) \\ \end{tabular} & \(G\). _lucidum_ & [47; 180] \\ \hline
**366.** &
\begin{tabular}{c} Lucidenic acid D \\ \end{tabular} & - & \(G\). _lucidum_ & [290] \\ \hline
**367.** & \
\begin{tabular}{c} Cytotoxicity against HL-60 \\ (61.0 uM), HepG2,1.64 \(\times\) 10\({}^{-4}\) \\ \end{tabular} &
\begin{tabular}{c} Cytotoxicity against HL-60 \\ (61.0 uM), HepG2,1.5 (2.05 \(\times\) 10\({}^{-1}\) uM), \\ \(\kappa\)B (16.9 uM), CCM2 (27.15 uM), \\ pS88 cells (12.0 \(\times\) 10\({}^{-2}\) uM) \\ \end{tabular} & \(G\). _lucidum_ & [47; 127] \\ \hline
**368.** & \
\begin{tabular}{c} Lucidenic acid B \\ \end{tabular} &
\begin{tabular}{c} Cytotoxicity against HL-60 \\ (9:3 uM), reduces PMA- \\ induced MMP-9 activity \\ and anti-invasive effects \\ \end{tabular} & \(G\). _lucidum_ & [47; 286] \\ \hline
**369.** & \
\begin{tabular}{c} Lucidenic acid C \\ \end{tabular} &
\begin{tabular}{c} Cytotoxicity against HL-60 \\ (45.2 uM) \\ \end{tabular} & \(G\). _lucidum_ & [47; 286] \\ \hline
**370.** & 20(21)-Dehydrolucidenic acid N & Anti-HIV protease (48.0 uM) & \(G\). _sinese_ & [192] \\ \hline
**371.** & 20-Hydroxluidenic acid A & Anti-HIV protease—NE & \(G\). _sinese_ & [192] \\ \hline
**372.** & Methyl lucidenate D & - & \(G\). _lucidum_ & [184] \\ \hline
**373.** & Methyl lucidenate E & - & \(G\). _lucidum_ & [184] \\ \hline
**374.** & Methyl lucidenate F & - & \(G\). _lucidum_ & [184] \\ \hline \hline \end{tabular}
\begin{tabular}{c} Cytotoxicity (inhibition of \\ triglyceride accumulation in \\ between 45%-50% at 80 uM during \\ the differentiation of 3T3-L1 \\ preadipocytes) \\ \end{tabular} & \(G\). _lucidum_ & [292] \\ \hline
**376.** & Methyl lucidenate Ha & - & \(G\). _sinese_ & [198] \\ \hline
**377.** & Ethyl lucidenate A &
\begin{tabular}{c} Cytotoxicity against HL-60 \\ (25.9 uM/mL), CA6 cells \\ (20.4 uM/mL), \\ \end{tabular} & \(G\). _lucidum_ & [242] \\ \hline
**378.** & Butyl lucidenate N &
\begin{tabular}{c} Inhibits adipocyte \\ differentiation in 3T3-L1 cells: \\ inhibition of lipid droplet \\ formation (56\% at 40 ug/mL) \\ \end{tabular} & \(G\). _lucidum_ & [183] \\ \hline
**379.** & Butyl lucidenate A &
\begin{tabular}{c} Inhibits adipocyte \\ differentiation in 3T3-L1 cells: \\ differentiation of lipid droplet \\ differentiation (46\%–48\% at 40 ug/mL) \\ \end{tabular} & \(G\). _lucidum_ & [183] \\ \hline
**380.** & Butyl lucidenate P & Anti-inflammation (7.4 uM) & \(G\). _lucidum_ & [293] \\ \hline
**381.** & Butyl lucidenate D\({}_{2}\) & Anti-inflammation (35 uM) & \(G\). _lucidum_ & [293] \\ \hline \hline \end{tabular}
\end{table} 
Table 3: C27 Triterpenoids and bioactivities from _Ganoderma_. \begin{table}
\begin{tabular}{c c c c c} \hline \hline
**No. ** & **Trivial Names** & **Bioactivities (IC\({}_{\text{eq}}\)/MIC or ED\({}_{\text{eq}}\))** & **Sources** & **References** \\ \hline
**382. ** & Butyl1 lucidenate E\({}_{2}\) & Anti-inflammation (6.4 \(\mu\)M) & _G. lucidum_ & [293] \\ \hline
**383. ** & Butyl1 lucidenate Q & Anti-inflammation (4.3 \(\mu\)M) & _G. lucidum_ & [293] \\ \hline
**384. ** & 20-Hydroxylucidenic acid D\({}_{2}\) & - & _G. lucidum_ & [294] \\ \hline
**385. ** & 20-Hydroxylucidenic acid F & - & _G. lucidum_ & [294] \\ \hline
**386. ** & 20-Hydroxylucidenic acid E\({}_{2}\) & - & _G.