# _Helicobacter pylori_--The Bridge between Local and Systemic Inflammation in Children
## 3 Results
\begin{table}
\begin{tabular}{l c c c c} \hline \hline \multirow{2}{*}{**Parameters**} & \multirow{2}{*}{\begin{tabular}{c} _H. pylori_ \\ **Mean \(\pm\) SD, (Median)** \\ \end{tabular} } & \multirow{2}{*}{\begin{tabular}{c} **Non-\(H\). _pylori_ \\ **(n = 26)** \\ **Mean \(\pm\) SD, (Median)** \\ \end{tabular} } & \multirow{2}{*}{\
\begin{tabular}{c} **Control Group** \\ **(n = 28)** \\ **Mean \(\pm\) SD, (Median)** \\ \end{tabular} } & \multirow{2}{*}{
\begin{tabular}{c} _p Value_ \\ **Mean \(\pm\) SD, (Median)** \\ \end{tabular} } \\ \hline Erythrocytes (\(\times 10^{6}\)/\(\mu\)L) & 4.779 \(\pm\) 0.4147 (4.685) & 4.782 \(\pm\) 0.5510 (4.865) & 4.600 \(\pm\) 0.5893 (4.750) & 0.3918 \\ \hline MVP (fL) & 83.00 \(\pm\) 5.088 (82.65) & 81.37 \(\pm\) 4.522 (81.30) & 82.52 \(\pm\) 5.080 (81.70) & 0.5365 \\ \hline Htc (\%) & 39.58 \(\pm\) 3.081 (39.30) & 38.94 \(\pm\) 4.809 (39.70) & 37.87 \(\pm\) 5.601 (39.30) & 0.5653 \\ \hline MCHC (g/dL) & 34.41 \(\pm\) 0.9856 (34.40) & 33.75 \(\pm\) 1.562 (34.20) & 33.46 \(\pm\) 1.486 (33.80) & 0.0803 \\ \hline Hb (g/dl) & 13.64 \(\pm\) 1.235 (13.75) & 13.18 \(\pm\) 1.885 (13.55) & 12.74 \(\pm\) 2.115 (13.25) & 0.3549 \\ \hline Leukocytes (number/\(\mu\)L) & 8.106 \(\pm\) 2.567 (7.630) & 7.104 \(\pm\) 1.433 (6.925) & 8.290 \(\pm\) 3.696 (6.870) & 0.6541 \\ \hline Lymphocytes (number/\(\mu\)L) & 2.259 \(\pm\) 0.5576 (2.100) & 2.660 \(\pm\) 0.8269 (2.565) & 2.287 \(\pm\) 0.5990 (2.160) & 0.1819 \\ \hline Neutrophhls (number/\(\mu\)L) & 4.855 \(\pm\) 2.097 (4.235) & 3.431 \(\pm\) 1.413 (3.075) & 5.177 \(\pm\) 3.696 (3.780) & 0.1307 \\ \hline NLR & 2.223 \(\pm\) 1.034 (1.980) & 1.444 \(\pm\) 0.8351 (1.260) & 2.263 \(\pm\) 1.791 (1.790) & 0.0253 \\ \hline Eosinophils (number/\(\mu\)L) & 0.2214 \(\pm\) 0.1841 (0.1950) & 0.3615 \(\pm\) 0.4889 (0.1550) & 0.1836 \(\pm\) 0.2542 (0.1250) & 0.1017 \\ \hline ESR (mmHg) & 15.75 \(\pm\) 13.19 (14.00) & 11.91 \(\pm\) 14.38 (8.000) & 15.00 \(\pm\) 21.46 (11.00) & 0.2863 \\ \hline Iron (\(\mu\)mol/L) & 18.91 \(\pm\) 7.898 (20.25) & 16.16 \(\pm\) 8.775 (14.15) & 13.84 \(\pm\) 5.749 (14.68) & 0.2499 \\ \hline AST (U/L) & 23.48 \(\pm\) 8.569 (20.90) & 23.04 \(\pm\) 16.14 (19.95) & 22.19 \(\pm\) 11.16 (19.50) & 0.7679 \\ \hline ALT (U/L) & 13.82 \(\pm\) 4.853 (12.20) & 15.95 \(\pm\) 12.09 (12.60) & 18.81 \(\pm\) 24.45 (13.70) & 0.9612 \\ \hline GGT (U/L) & 16.20 \(\pm\) 6.546 (14.50) & 17.45 \(\pm\) 20.19 (13.00) & 20.76 \(\pm\) 30.70 (13.00) & 0.6024 \\ \hline \end{tabular} Legend: ESR—erythrocyte sedimentation rate, AST = _aspartate aminotransferase_, ALT = _alanine aminotransferase_, GGT = gamma-glutamyl transpeptidase, Hb—hemoglobin, Htc—hematocrit, MCHC—mean corpuscular hemoglobin concentration, MVP—mean platelet volume, NLR—neutrophil to lymphocyte ratio, n—number, SD—standard deviation, Mann–Whitney test was used.  
\end{table} 
Table 3: The difference of median values of NLR between the three groups. Figure 1: The difference of median values of NLR between the three groups. Figure 2: The difference of median values of MCHC between the three groups. \begin{table}
\begin{tabular}{l l c} \hline \hline  & **Dunn’s Multiple Comparison Test** & **Significant? \(p\) \(<\) 0.05?** \\ \cline{2-3}
**MCHC** (g/dL) & \(H\). _pylori_-induced gastritis vs. non-_H. pylori_ gastritis & 0.0499 \\ \cline{2-3}  & \(H\). _pylori_-induced gastritis vs. control group & 0.0489 \\ \cline{2-3}  & non-_H. pylori_ gastritis vs. control group & 0.5211 \\ \hline Legend: MCHC—mean corpuscular hemoglobin concentration; statistical significance (\(p\)\(<\) 0.05), Kruskal–Wallis test. & \\ \hline \hline \end{tabular}
\end{table} 
Table 4: The difference of median values of MCHC between the three groups. Assessing the presence of IL 6 on gastric biopsy samples by immunohistochemical method, we did not obtain any correlations between gastritis in children and control group [RR = 1.283, IC (95%): 0.9404-1.751, \(p\) = 0.0988].