## 3 Results and Discussion
### Determination of Phenolic Compounds  
The analyses to determine the phenolic composition of chamomile and sage aqueous infusions were performed at 80 \({}^{\circ}\)C, which was found to be the optimal temperature concerning bioactivity. In Table 2, the phenolic compounds of both aqueous extracts are presented. Thirteen main phenolic compounds were detected in chamomile aqueous extracts and 11 were identified. Chamomile extract contained six flavonoids including flavone glycosides (apigenin-7-O-glucoside and luteolin-7-O-glucoside) and flavonoids (kaempfer and rutin trihydrate). Phenolic acids as caffe, chlorogenic, cis-3,5-O-dicaffeoylquinic, trans-3,5-O-dicaffeoylquinic, and ferulic acid were also detected in the chamomile infusion, as shown on Figure 3. Compounds 4 and 5 yielded both the same ion [M-H]\({}^{-}\) at \(m\)/\(\varepsilon\) 515, which allowed tentative identification as cis and trans isomers of 3,5-O-dicaffeoylquinic acids, respectively. These phenolic acids presented similar fragmentation pattern to the ones previously reported by [PERSON] et al. Compounds 10 and 11 were identified as apigenin-7-O-acetyl glucose and the other derivative apigenin 7-O-glucuronide, by comparison of mass spectrums with literature data [18; 35]. Rutin trihydrate, ferulic acid, chlorogenic acid, and apigenin-7-O-glucose were the dominant compounds of chamomile infusion. Apigenin-7-O-acetyl glucose and trans-3,5-O-dicaffeoylquinic acid followed. At lower and similar amounts, apigenin 7-O-glucuronide, cis-3,5-O-dicaffeoylquinic acid, caffe acid, kaempfer, and luteolin-7-O-glucose were identified. Figure 2: Box plots and scatterplots, presented as medians and ranges, concerning Folin–Ciocalteu (total phenolic content (TPC)) and 2,2-diphenyl-I-picrylhydrazyl hydrate (DPPH) assays. Flavone glycosides (apigenin-7-\(O\)-glucose and luteolin-7-\(O\)-glucose), chlorogenic acid, caffeic and ferulic acid derivatives were previously identified in chamomile water extracts [18]. Moreover, the presence of apigenin-7-glucoside as the main flavonoid of aqueous chamomile extracts was described by different authors [10; 36; 37]. Luteolin-7-\(O\)-glucose, chlorogenic acid, and dicaffeoylquinic acids have also been detected in aqueous extracts (infusions, decoctions) of chamomile flower heads and leafy flowering stems [8]. Rutin (trihydrate) (quercetin-3-\(O\)-rutinoside), as far as we know, has not been cited in aqueous extracts of chamomile, although other derivatives of quercetin were found in chamomile infusions [18; 35; 38]; although other studies detected rutin at aqueous chamomile obtained by supercritical extraction [19; 39]. The decoctions of _M. recutia_ presented significant contents of caffeic acid, 7-\(O\)-glucose of apigenin, and luteolin [35]. [PERSON] with co-authors also investigated chamomile infusions. The major phenolic compounds in the chamomile infusions were also chlorogenic acid, dicaffeoylquinic acids, apigenin glycoside and acetyl glucose, ferulic acid glycoside, and at low content glucoside of luteolin [38]. Remarkable contents of chlorogenic and caffeic acid were found in chamomile infusions, whilst ferulic acid was found at low contents. Moreover, glucosides (7-\(O\)) of apigenin and luteolin were identified [32]. Another study also examined chamomile aqueous extract at 80 \({}^{\circ}\)C, and demonstrated ferulic, caffeic, and \(p\)-cumaric acids as the main compounds, followed by lower content of chlorogenic acid [1]. In the case of sage aqueous extracts, 11 phenolic compounds were found. Up to 10 different phenolic compounds, consisting of four phenolic acids and six flavonoids, were identified in sage aqueous extract, as presented in Figure 4. The flavonoids were composed of myricitrin, apigenin-7-\(O\)-glucuron, hispidulin glucoside, and luteolin derivatives (7-\(O\)-glucose, 7-\(O\)-glucuron, and 7-\(O\)-rutinoside). Phenolic acids determined in sage aqueous extract were \(p\)-cumaric, rosmarinic, salvianolic B and K acids.