## 3 Results  
The effect of guarana extract and/or WBV on the biodistribution of radiopharmaceutical sodium pertechnate was evaluated. The %ATI/g of the Na\({}^{99\text{m}}\)ToC\({}_{4}\) on the organs isolated from the rats submitted to the different treatments are shown in Table 1. The uptake of the radiopharmaceutical in muscle increased (i) significantly (\(p<0.05\)) in the GUA group and (ii) did not increase in the GUA + WBV-E as compared with the CON group, with a moderate relationship (\(\epsilon^{2}=0.4979\)). No differences were observed in the other organs and the \(\epsilon^{2}\) was small (0.0177 to 0.4280). Although without significant difference, the uptake of sodium pertechnate in the prostate increased in the GUA, WBV-E, and GUA+WBV-E. The effect of guarana extract and/or WBV on the concentration of blood biomarkers are shown in Table 2. After 6-weeks of all interventions, there was an increase in the calcium levels (\(p>0.05\)) of the animals submitted to WBV (WBV-E and GUA + WBV-E) as compared with the animals in the GUA group. No differences were found in the other biomarkers. The \(\varepsilon^{2}\) revealed values from 0.0291 to 0.3995 (small relationship). The evaluation of the effect of guarana extract and/or WBV on the enzymatic activities after 6-weeks revealed no differences in the blood concentration of the enzymes evaluated amongst the rats submitted to the always treatments (Table 3). The \(\varepsilon^{2}\) indicated no relationship. \begin{table}
\begin{tabular}{c c c c c c c} \hline
**OGANS** & **CON** & **GUA** & **WBV-E** & **GUA+WBV-E** & \(p\) & \(\epsilon^{2}\) \\ \hline Thyroid & \(7.82\pm 2.75\) & \(7.76\pm 2.30\) & \(7.81\pm 1.25\) & \(7.91\pm 0.54\) & 0.8142 & 0.0631 \\ Stomach & \(5.16\pm 1.54\) & \(5.69\pm 2.05\) & \(5.93\pm 1.46\) & \(8.55\pm 1.43\) & 0.1134 & 0.3727 \\ Bowel & \(1.15\pm 0.28\) & \(1.65\pm 0.21\) & \(1.22\pm 0.22\) & \(1.39\pm 0.27\) & 0.1120 & 0.4280 \\ Kidney & \(1.57\pm 0.11\) & \(1.60\pm 0.23\) & \(1.66\pm 0.38\) & \(1.60\pm 0.14\) & 0.5756 & 0.1103 \\ Liver & \(1.86\pm 0.45\) & \(2.45\pm 0.63\) & \(2.33\pm 0.42\) & \(2.42\pm 0.43\) & 0.4078 & 0.1525 \\ Pancreas & \(1.30\pm 0.16\) & \(0.85\pm 0.34\) & \(1.31\pm 0.25\) & \(1.29\pm 0.40\) & 0.2268 & 0.2554 \\ Brain & \(0.07\pm 0.04\) & \(0.10\pm 0.02\) & \(0.09\pm 0.03\) & \(0.10\pm 0.01\) & 0.8185 & 0.0546 \\ Bone & \(0.41\pm 0.19\) & \(0.69\pm 0.20\) & \(0.51\pm 0.10\) & \(0.66\pm 0.18\) & 0.1718 & 0.2632 \\ Lung & \(1.85\pm 0.64\) & \(1.95\pm 0.29\) & \(1.81\pm 0.53\) & \(2.01\pm 1.38\) & 0.9529 & 0.0177 \\ Heart & \(1.01\pm 0.73\) & \(0.92\pm 0.42\) & \(1.02\pm 0.18\) & \(1.14\pm 0.39\) & 0.7160 & 0.0797 \\ Spleen & \(1.00\pm 0.09\) & \(1.17\pm 0.18\) & \(1.15\pm 0.26\) & \(1.06\pm 0.10\) & 0.5052 & 0.1299 \\ Muscle & \(0.27\pm 0.11\) & \(0.43\pm 0.07\) * & \(0.28\pm 0.06\) & \(0.35\pm 0.02\) & 0.0298 & 0.4979 \\ Penis & \(1.63\pm 0.26\) & \(1.79\pm 0.36\) & \(1.69\pm 0.21\) & \(1.73\pm 0.39\) & 0.7487 & 0.0641 \\ Prostate & \(0.53\pm 0.14\) & \(0.90\pm 0.23\) & \(0.77\pm 0.29\) & \(0.93\pm 0.21\) & 0.0983 & 0.3311 \\ Seminal vesicle & \(0.54\pm 0.21\) & \(0.54\pm 0.16\) & \(0.44\pm 0.14\) & \(0.54\pm 0.19\) & 0.7489 & 0.0641 \\ Bladder & \(1.28\pm 0.15\) & \(1.68\pm 0.46\) & \(1.32\pm 0.34\) & \(1.30\pm 0.55\) & 0.4659 & 0.1963 \\ Testis & \(0.55\pm 0.17\) & \(0.51\pm 0.19\) & \(0.48\pm 0.04\) & \(0.56\pm 0.16\) & 0.6125 & 0.0953 \\ Blood & \(2.58\pm 0.61\) & \(2.52\pm 0.35\) & \(2.79\pm 1.66\) & \(2.95\pm 0.88\) & 0.7817 & 0.0721 \\ \hline \end{tabular}
\end{table} 
Table 1: %ATI/g of the Na\({}^{99}\)mT\(\rm{CO_{4}}\) from organs isolated from the rats submitted to some interventions.