# Colorectal Cancer Detection Tool Developed with Neural Networks
## 2 Materials and Methods
### The Datasets
\begin{table}
\begin{tabular}{c c} \hline
**Variable Name** & **Impact of the Variable** \\ \hline Albumin & It can be used to track the nutritional and systematic inflammatory status of cancer patients. It has been found to be an independent prognostic in colorectal cancer, lung cancer, lymphoma, and even breast cancer. Usually, symptoms associated with high levels of albumin are dehydration and diarrhea. \\ \hline Alkaline Phosphatase (ALP) & It is an enzyme associated with hepatobilary diseases. Several reports show that ALP is used as a prognostic for colon, lung, and liver cancer (or other liver-associated diseases). \\ \hline Gamma GT & It is known as gamma-glutamyl transferase, and it has been shown to have an increase in cancer patients. Usually a marker for diabetes, cardiovascular, or kidney-associated diseases, but recently it has been proven to be related to different cancer types as well. \\ \hline GOT & An enzyme found in the liver and heart cells is released in the blood when either of these are damaged. A high value can be associated with cancer. \\ \hline GPT & An enzyme that is found in the liver and some other tissues. If it is found in the blood, it may be a sign of liver damage or cancer. People who present high values for the GPT are sent to get evaluated by gastroenterologists. \\ \hline Total Protein & Parameters are usually measured to detect the amount of protein in a person’s blood. These tests can be used to diagnose several conditions like cancer and kidney or liver diseases. \\ \hline Iron & Excess iron, which cannot be assimilated by metabolism, can be associated with cancer. The most relevant one is leukemia, but in the case of colorectal cancer, there is a deficiency of iron and anemia. \\ \hline Hemoglobin & The level of hemoglobin in a cancer patient is usually found in a declining state; it can start even 4 years before the diagnosis of the disease. A low hemoglobin level is associated with anemia. \\ \hline MCV & It is used to measure the average red blood cell in a person. It can be used to detect B12 deficiency, but if the value is high, it can be associated with cancer. \\ \hline Erythrocytes & Red blood cells in low numbers can be associated with cancer. \\ \hline MCH & Mean corpuscular hemoglobin is the average amount of hemoglobin found in the blood cells. \\ \hline MCHC & Mean corpuscular hemoglobin concentration is the average amount of hemoglobin found in a group of red blood cells. \\ \hline Hematocrits & It is the volume percentage of red blood cells in blood. \\ \hline Thrombocytes & Also known as platelets, they are the cells in the blood that form the clots. An elevated platelet count can be linked to the development of tumors. \\ \hline \end{tabular}
\end{table} 
Table 3: The impact of the main variable. As previously stated, the public Kvasir dataset is employed, comprising a total of 1000 images of colonoscopies. The images are divided into two categories: one for healthy images and one for images that contain polyps (patients affected by CRC). In experimental settings, a third label is incorporated for images depicting ulcerated colons. Given that dimensions constitute a significant challenge, the images undergo resizing to ensure manageability. Initially, the images are resized to 128 \(\times\) 156, and subsequently to a range of larger resolutions, with the objective of preserving a substantial amount of information. Given that the issue pertains to the computational capacity, the images undergo a transformation from RGB to gray format. Consequently, the input matrix undergoes a reduction from a three-dimensional array to a one-dimensional array (the RGB format utilizes three matrices as inputs, whereas the grayscale format employs a single matrix). The benefit of this approach is that it significantly reduces the number of computations. However, it should be noted that this reduction in computations also results in a concomitant reduction in the amount of information.