# Benefits of Probiotics--Biodetoxification
## 4 Probiotics--Advantages of Biodetoxification  
According to the literature, detoxifying can improve the human body's ability to absorb nutrients [32]. Removing toxins from the body helps prevent inflammation and supports immune system function. When combined, probiotics and biodetoxification work synergistically to enhance overall wellness. Probiotics promote a healthy gut, which is essential for effective detoxification. A well-balanced microbiome helps the body break down and eliminate toxins more efficiently. Food contamination by mycotoxins is a great threat to food safety [148]. With mycotoxin detoxification by microorganisms, the biological process is reliable, efficient, less costly, and easier to use than physical and chemical ones. However, it is important to discover the metabolite's toxicity resulting from mycotoxin biodegradation. Microorganisms exhibiting activity against mycotoxins have important properties that can be used in the future to develop biological preservation methods based on enzymes produced by these microorganisms.  
In vitro studies show promising results for the use of probiotics to detoxify xenobiotics and pollutants. These studies evaluate the effectiveness of different probiotic strains in breaking down harmful substances and converting them into less toxic forms. This approach can lead to safer food products that do not have a negative impact on the health of the consumer. Although probiotic supplementation may reduce the toxicity of xenobiotics, it should be recognized that food is a complex matrix containing many different xenobiotics that may exhibit synergistic or additive properties [149]. This should be taken into account when evaluating the effectiveness of biodetoxification methods. A common source of probiotics is fermented foods. As fermentation is a natural, traditional, and effective method of food preservation, the use of chemical preservatives is significantly reduced or they are not used at all. The presence of xenobiotics in such products is rather the result of contamination of the raw product, the source of which is, among other things, environmental pollution. [PERSON] et al. highlighted that the consumption of fermented dairy products supplemented with xenobiotic-binding probiotic strains could provide a simple and effective method of mitigating the adverse effects of food contaminants. In this regard, the use of probiotic biodegradation appears to be particularly relevant in regions with high levels of pollution [150]. [PERSON] et al. tested the ability of 37 LAB and 13 yeast strains in binding acrylamide. The most effective acrylamide binding ability was found in _Pediococcus acidilactici_, achieving reduction of acrylamide levels by 87.6%. It should be noticed that the acrylamide binding ability remained comparably high when non-viable cells (thermally inactivated) were used. In addition to detoxification, the tested strains decreased acrylamide-induced DNA damage, therefore reducing its genotoxicity. The reported findings indicate that LAB and yeast possess great potential for the detoxification of food contaminated with acrylamide and reducing its harmful genotoxic effects [151].  
The large-scale application of biodetoxification methods in both agriculture and the food industry is a challenge for the future. The widespread and successful implementation of probiotic microorganisms in this field may be of great importance for food safety. It can contribute to the limited use or even replacement of the traditional chemical and physical methods by an eco-friendly biological approach [62; 152]. In addition, it should be mentioned that the use of probiotics can support the detoxification of xenobiotics already present in the body and has many other health-promoting benefits for the host [32].