## 4 Results
### Derivation of Human BDS in Human Infant CHD
\begin{table}
\begin{tabular}{c c c c c c c} \hline \hline
**Dependent** & **Independent** & **N-Used** & **R-Square** & \(p\)**-Value** & **Estimate** \\ \hline BDS & Sex & 344 & 0.008447 & 0.0887 & 0.680037 \\ \hline BDS & Genetic Abnormality & 252 & 0.045926 & **0.0006** & \(-1.66277\) \\ \hline BDS & GA & 341 & 0.00002 & 0.9352 & \(-0.00562\) \\ \hline BDS & PCA & 343 & 0.002649 & 0.3419 & 0.017322 \\ \hline BDS & Birth Weight & 248 & 0.000337 & 0.7737 & \(-9.1\times 10^{-5}\) \\ \hline BDS & Pre/Post operative status & 343 & 0.000662 & 0.6349 & \(-0.18132\) \\ \hline BDS & Term/Preterm & 343 & 0.000651 & 0.6378 & \(-0.23214\) \\ \hline \hline \end{tabular} Note: Bolded values indicate statistically significant results.  
\end{table} 
Table 3: Correlation of Brain Dysplasia Score (BDS) with Demographic Factors (CHD cohort, Univariate Analysis). \begin{table}
\begin{tabular}{c c c c c c c c} \hline \hline
**Dependent** & **Independent** & **N-Used** & **R-Square** & \(p\)**-Value** & **Estimate** \\ \hline BDS & Sex & 490 & 0.000026 & 0.9096 & \(-0.0359\) \\ \hline BDS & GA & 487 & 0.003619 & 0.1851 & 0.058461 \\ \hline BDS & PCA & 489 & 0.001664 & 0.368 & 0.011933 \\ \hline \hline \end{tabular}
\end{table} 
Table 2: Correlation of Brain Dysplasia Score (BDS) with Demographic Factors (entire cohort: Univariate Analysis). \begin{table}
\begin{tabular}{c c c c c c c c} \hline \hline
**Dependent** & **Independent** & **N-Used** & **R-Square** & \(p\)**-Value** & **Estimate** \\ \hline BDS & Sex & 344 & 0.008447 & 0.0887 & 0.680037 \\ \hline BDS & Genetic Abnormality & 252 & 0.045926 & **0.0006** & \(-1.66277\) \\ \hline BDS & GA & 341 & 0.00002 & 0.9352 & \(-0.00562\) \\ \hline BDS & PCA & 343 & 0.002649 & 0.3419 & 0.017322 \\ \hline BDS & Birth Weight & 248 & 0.000337 & 0.7737 & \(-9.1\times 10^{-5}\) \\ \hline BDS & Pre/Post operative status & 343 & 0.000662 & 0.6349 & \(-0.18132\) \\ \hline BDS & Term/Preterm & 343 & 0.000651 & 0.6378 & \(-0.23214\) \\ \hline \hline \end{tabular} Note: Bolded values indicate statistically significant results.  
\end{table} 
Table 4: Correlation of Brain Dysplasia Score (BDS) with Demographic Factors in (CHD cohort, Multivariate Analysis). \begin{table}
\begin{tabular}{c c c c c c c c} \hline \hline  & & & & & **Main Independent Factor** & **PCA** & \\ \hline  & **N-Used** & **Model p** & **R-Square** & \(p\)**-Value** & **Estimate** & \(p\)**-Value** & **Estimate** \\ \hline Hemorrhage & 340 & 0.9876 & 0.000001 & 0.9876 & 0.010146 & — & — \\ \hline Infarction & 341 & 0.604 & 0.000794 & 0.604 & 0.345161 & — & — \\ \hline Hypoxic ischemic injury & 328 & 0.6111 & 0.000794 & 0.6111 & \(-0.55119\) & — & — \\ \hline Punctate white matter lesion & 342 & 0.8922 & 0.000054 & 0.8922 & 0.071424 & — & — \\ \hline Any brain injury, dichotomized & 344 & 0.5548 & 0.001021 & 0.5548 & 0.243539 & — & — \\ \hline Brain injury composite score & 344 & 0.9042 & 0.000042 & 0.9042 & \(-0.03758\) & — & — \\ \hline Maturation, Cortical Fold & 332 & **0.0016** & 0.029645 & 0.0016 & \(-0.7302\) & — & — \\ \hline Maturation, Frontal Cortex & 332 & **<0.0001** & 0.061511 & \(<\)0.0001 & \(-0.80238\) & — & — \\ \hline Maturation, Insular Cortex & 332 & **<0.0001** & 0.067464 & \(<\)0.0001 & \(-1.01932\) & — & — \\ \hline Maturation, Cortical Fold \& PCA & 331 & **0.0044** & 0.032554 & 0.001 & \(-0.78513\) & 0.3255 & 0.02414 \\ \hline Maturation, Frontal Cortex \& PCA & 331 & **<0.0001** & 0.067676 & \(<\)0.0001 & \(-0.86858\) & 0.1531 & 0.034607 \\ \hline Maturation, Insular Cortex \& PCA & 331 & **<0.0001** & 0.07442 & \(<\)0.0001 & \(-1.10484\) & 0.146 & 0.035021 \\ \hline \hline \end{tabular} Note: Bolded values indicate statistically significant results.  
\end{table} 
Table 5: Correlation of Brain Dysplasia Score, Brain Injury, and Cortical Maturation Score (TMS).