## 5 Discussion
The middle kidney section usually has the largest area, while the end sections (first and last) are the smallest. Depending on the way the verification data is prepared by the expert, the end section may even have several pixels. With such a small pixel value, even a small and insignificant error (several pixels) is reflected in a large decrease of F1-score. In the CI test, after rejecting the extreme values, it can be seen that most of the data is in the range of 86-92 and measured in paired-sample \(t\)-test a value of \(p\) is below 0.0004 which shows significant reliability of the presented method. The proposed techniques can be successfully used in hospitals and other medical centers dealing with medical imaging diagnostics. Our study has some limitations. Left and right kidneys are detected separately. This problem can be partially solved by using parallel computing. Our technique for the analysis of subsequent slices requires a prior calculation of the previous slice. Therefore, it is not possible to selectively analyze individual scans without keeping the order of image processing. Despite the satisfactory results of the developed system, it is necessary to continue research and development of computer-aided medical diagnostics methods to increase the sensitivity and precision of detection, as well as the ability to recognize other pathophysiological changes and organs. Conceptualization: T.L., T.M. ; methodology: T.L., T.M. ; software: T.L. ; resources: M.D. and M.L. ; data curation: M.L. ; writing--T.L. ; writing--review and editing, T.L. and T.M. ; visualization, T.L. ; supervision, T.M. All authors have read and agreed to the published version of the manuscript. This research was funded by the National Science Centre, Poland, grant number 2016/23/B/ST6/00621. The authors declare no conflict of interest. The Institute for Health Metrics and Evaluation. Available online: [[http://www.healthdata.org](http://www.healthdata.org)]([http://www.healthdata.org](http://www.healthdata.org)) (accessed on 23 October 2020). [PERSON] et al. (2012) [PERSON]; [PERSON]; [PERSON] [PERSON]; [PERSON] [PERSON]; [PERSON] [PERSON]; [PERSON]; [PERSON] _Campbell-Walsh Urlogy 10 th Edition_; Elsevier: Amsterdam, The Netherlands, 2012. [PERSON]; [PERSON] _Nowotwory i Torbiele Nerek_; PZWL: Warsaw, Poland, 2002. [PERSON]; [PERSON]; [PERSON] [PERSON]; [PERSON]; [PERSON]; [PERSON]; [PERSON]; [PERSON]; [PERSON]; [PERSON]; et al. _Guidelines on Renal Cell Carcinoma_; European Association of Urology: Arnhem, The Netherlands, 2015. [PERSON]; [PERSON] [PERSON]; [PERSON]; [PERSON]; [PERSON] Histopathology of surgically managed renal tumors: analysis of a contemporary series. _Urology_**2003**, _62_, 827-830. [CrossRef]  
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