## 3 Results
### Clinical Outcomes  
Marginal Bone Level MBL measurements were conducted on radiographs taken at baseline, 6 and 12-month follow-ups (Table 2). Due to possible differences in MBL values at baseline between test and control implants, a statistical comparison between test and control implants was performed on the difference between MBL values at 6-month or 12-month follow-ups and MBL value at baseline (i.e., \(\Delta\text{MBL}_{\text{6-month}}=\text{MBL}_{\text{6-month}}-\text{MBL}_{ \text{baseline}}\)). \begin{table}
\begin{tabular}{c c c c c} \hline \hline \multirow{2}{*}{**Patient**} & \multirow{2}{*}{**Age**} & \multirow{2}{*}{**Sex**} & \multicolumn{2}{c}{**Control Implant**} & \multicolumn{1}{c}{**Test Implant**} \\  & & & & **(Location; Size-mm)** & **(Location; Size-mm)** \\ \hline Patient 1 & 91 & M & 46; 4.6 \(\times\) 9 & 36; 4.6 \(\times\) 9 \\ Patient 2 & 63 & F & 14; 3.8 \(\times\) 12 & 47; 4.6 \(\times\) 7.5 \\ Patient 3 & 45 & F & 15; 3.8 \(\times\) 10.5 & 46; 4.6 \(\times\) 9 \\ Patient 4 & 45 & F & 35; 3.8 \(\times\) 9 & 36; 4.6 \(\times\) 9 \\ Patient 5 & 77 & F & 36; 3.8 \(\times\) 9 & 35; 3.8 \(\times\) 10.5 \\ Patient 6 & 58 & F & 45; 3.8 \(\times\) 9 & 46; 4.6 \(\times\) 9 \\ Patient 7 & 74 & M & 26; 4.6 \(\times\) 9 & 16; 4.6 \(\times\) 7.5 \\ Patient 8 & 57 & F & 46; 4.6 \(\times\) 9 & 36; 4.6 \(\times\) 9 \\ Patient 9 & 70 & M & 35; 4.6 \(\times\) 7.5 & 36; 4.6 \(\times\) 7.5 \\ Patient 10 & 29 & M & 46; 4.6 \(\times\) 10.5 & 36; 4.6 \(\times\) 9 \\ Patient 11 & 61 & F & 27; 3.8 \(\times\) 9 & 36; 4.6 \(\times\) 9 \\ Patient 12 & 54 & M & 26; 4.6 \(\times\) 7.5 & 25; 3.8 \(\times\) 9 \\ Patient 13 & 56 & F & 36; 4.6 \(\times\) 9 & 35; 3.8 \(\times\) 9 \\ \hline \hline \end{tabular}
\end{table} 
Table 1: Patient demographics, site and size of the implants. Figure 2: Consort Flow Diagram. Mann-Whitney non-parametric tests comparing the \(\Delta\)MBL accounting for the two independent factors (test and control implants) showed no significant differences at 6-month (\(p\) = 0.30) and 12-month follow-ups (\(p\) = 0.85). As second level analyses, the temporal evolution of MBL values for test and control implants was statistically evaluated separately. The [PERSON] nonparametric statistic for correlated samples showed significant differences in MBL values for baseline, 6-month and 12-month follow-ups in test implants (\(p\) = 0.004) (Figure 3). Post-hoc analysis showed a significant difference between MBL values at baseline and at 6-month follow-up (\(p\) = 0.006). The same trend was found in the control implants, but the difference was not considered statistically significant (\(p\) = 0.067). Marginal Tissue Height. As for MTB measurements, a first statistical comparison was performed between test and control implants on the difference of MTH values at 12-month follow-ups and baseline (i.e., \(\Delta\)MTB\({}_{\text{12-month}}\) = MTB\({}_{\text{12 month}}\) - MTB\({}_{\text{baseline}}\)). Mann-Whitney tests showed no difference on \(\Delta\)MTH values at 12-month follow-ups between test and control implants (\(p\) = 0.40). In addition, MTH values were not significantly different at baseline and at 12-month follow-up in test (\(p\) = 0.95) and in control (\(p\) = 0.20) implants when test and control implants were analysed separately. Peri-implant Probing Depths. PPD values where not found to be significantly different between test and control implants at baseline (\(p\) = 0.47) and at 12-month follow-up (\(p\) = 0.25). In addition, PPD values were not significantly different at baseline and at