## 3 Results  
A total of 52 patients with PD participated in the study, and no patients were discharged for the duration. Table 1 shows the main characteristics of the sample. As is shown, both groups were homogeneous, with no statistically significant differences. \begin{table}
\begin{tabular}{l c c c c} \hline \hline
**Variables** & **All (n = 52)** & \begin{tabular}{c} **EG (MOTOD® + IVR)** \\ **(n = 30)** \\ \end{tabular} & \
\begin{tabular}{c} **CG (MOTOD®)** \\ **(n = 22)** \\ \end{tabular} &
\begin{tabular}{c} **Student’s t and** \\ **Chi-Squared Test** \\ **Results** \\ \end{tabular} \\ \hline Age (years) & 70.79 \(\pm\) 6.59 & 70.87 \(\pm\) 6.67 & 70.59 \(\pm\) 6.67 & t = 0.127; \(p\) = 0.899 \\ Sex (\% of women) & 42.31 & 36.67 & 50 & \\ Time diagnosed (years) & 6.40 \(\pm\) 4.77 & 5.60 \(\pm\) 4.06 & 8.23 \(\pm\) 5.88 & t = 1.470; \(p\) = 0.080 \\ \hline Hoehn and Yahr scale & 1.82 \(\pm\) 0.87 & 1.71 \(\pm\) 0.90 & 2.08 \(\pm\) 0.76 & t = \(-\)1.287; \(p\) = 0.103 \\ Stage 1 (\%) & 37.30 & 51.60 & 23.10 & \\ Stage 2 (\%) & 39.23 & 32.30 & 46.15 & Chi = 5.613; \(p\) = 0.132 \\ Stage 3 (\%) & 23.47 & 16.20 & 30.75 & \\ \hline First symptom & & & & \\ Tremors (\%) & 40.80 & 38.70 & 42.90 & \\ Rigidity (\%) & 20.75 & 12.90 & 28.60 & Chi = 4.729; \(p\) = 0.193 \\ Bradikinesia (\%) & 17.15 & 12.90 & 21.40 & \\ Other (\%) & 21.30 & 35.50 & 7.10 & \\ \hline Pharmacology & & & & \\ Equivalent dose of & & & & \\ levodopa LEDD (mg) & 532.33 \(\pm\) 229.75 & 538.94 \(\pm\) 161.92 & 526.33 \(\pm\) 297.53 & t = 1.001; \(p\) = 0.129 \\ \hline \hline \end{tabular}
\end{table} 
Table 1: General characteristics of the EG and CG (first reading). Figure 2: An example of a virtual scenario and user pedaling on a smart cycloergometer. Regarding the characteristics of the high-intensity aerobic exercise program carried out, it should be noted that the patients as a whole completed an average of 42 sessions during the 6 months of intervention (range: 40-48). Furthermore, taking into account the seven phases that each session consisted of, we should also highlight that of the 25 min each session lasted, on average, 626.62 \(\pm\) 259.72 s (range: 300-1148 s) of exercise were carried out actively while 893.91 \(\pm\) 341.80 s (range: 419-1215 s) were performed passively, and the average distances covered per session were 4400.14 \(\pm\) 1945.84 m actively (range: 1000.15-7966.18 m) and 5496.18 \(\pm\) 2545.53 m passively (range: 2039.75-8001.7 m). In the Supplementary Material (Table S1), the details of the intervention program carried out for both the EG and CG are presented. The following variables were analyzed: duration of the program, distance covered, pedaling symmetry, resistance tolerated, average speeds of the active and passive phases, energy consumed, work performed, muscle tone, any identified spasms, and each participant's perception of effort. The comparative study between both groups indicated no significant differences between the control group and the experimental group. Therefore, the program carried out on the smart cycloergometer was similar for both groups. The use of an IVR headset did not modify the execution parameters of the program undertaken in any of the phases of analysis carried out. Table 2 shows in detail the differential study of the effects of the intervention program in both groups with respect to the functional parameters. These data show that the use of an IVR headset in the EG led to statistically significant improvements when compared with the CG in terms of dynamic balance, gait, and risk of falling, all of which are parameters of vital importance in the population diagnosed with PD. Table 3 shows the comparative study between the two groups in terms of the quality-of-life parameters and disease symptomatology pre-intervention and post-intervention.