## 1 Introduction  
Influenza viruses, causing serious illness, deaths, and fear, have globally devastated the human and poultry population [1]. Avian Influenza viruses belonging to the orthomyx-ovriidae family are generally categorized by two surface antigens, Hemagglutinin (HA) and neuraminidase (NA), which bridge the biological system to infect birds, humans, and other mammalians [2]. The Avian Influenza Virus H9N2, initially isolated from china poultry forms in 1994, has been shown to infect humans by crossing species barriers [3]. The concerns about its pandemic potential have been compelling researchers to recognize and sort alternative anti-influenza agents with a different mechanism of action [4]. However, the shifting and drifting of the various influenza virus strains, their emerging drug resistance, and the limitations of antiviral drugs have posed a serious threat against the survival of humans and animals [5]. Different kinds of influenza have different abilities to resist antiviral medicines, but mainly two approaches, injectable vaccines and antiviral agents, are used to control it [1]. In the biomedical field, metal nanoparticles have been studied enormously to develop vaccines and antiviral drugs against influenza viruses. [PERSON] et al. comprehensively studied the antiviral activity of silver nanoparticles (AgNPs) on the H3N2 virus, where AgNPs selectively destroyed the virus structure [6]. In another previous investigation, AgNPs showed an efficient inhibitory activity on H1N1 influenza A virus in the hemagglutination of a chicken RBCs Assay Inhibition test by using an embryonated chicken egg as a cell culture [7]. Gold nanoparticles (AuNPs) have ideal opportunities to have bio conjunctions, particularly with influenza viruses, and can interact directly with the cell surface and block viral attachments [8]. More recently, [PERSON] and co-workers reported a strong antiviral activity of porous AuNPs on H1N1 and H9N2 influenza virus strains in an HA protocol using MDCK cells as a culture medium [9]. In one of the previous cases of research, gold nanoparticles of a size of 14 nm were found to be more effective in inactivating hemagglutination than that of a 2 nm size [10]. It is seen in previous research that metallic NPs have been extensively explored as antimicrobial agents, but at the same time, there have been stability, biocompatibility, non-degradability, and toxicity issues [11; 12]. These issues have limited their applications in the medical field [13]. Thus, the researchers have revisited their strategies in exploring noble metal nanostructures in the medical field [14]. The behavior of a mixture of nanoparticles (NPs) and polymers, referred to as nanocomposites (NCs), has piqued the scientific community's curiosity. A nanocomposite is a mixture of a metal-polymer material with at least one dimension in a nanoscale regime of 1-100 nm [15]. PVP and PEG are WHO-endorsed synthetic polymers, known to be well tolerated by the human body [16]. Their association with noble metal NPs makes most admirable hybrid nanostructures. These nanocomposites can mitigate the effects of microbial infections by enhancing stability, boosting biological activity, and lowering toxicity [17]. Recently an enhanced antiviral activity of ZnO-PEG NPs as compared to bare ZnO NPs has been reported [18]. In another research activity, small silver NPs in chitosan showed a stronger capability for inhibiting the H1N1 virus [19]. For the synthesis of metallic NPs/NCs, different approaches have been adopted, including physical [20], Chemical [21], and biological routes [22]. Among these techniques, atmospheric pressure microplasma has been the most admired bottom-up approach to nanoparticle synthesis [23]. In this process, electrons with other plasma species are produced in an argon/helium gas-assisted DC microplasma discharge at the surface of the metal precursor solution. The reduction of metal cations occurs due to interaction with microplasma-generated energetic electrons.