## 4 Results
\begin{table}
\begin{tabular}{l c c c} \hline \hline
**Clinical Symptoms** & **Abs.** & **P ES (\%)** & **95\% CI** \\ \hline Epileptic seizures: & 321 & 88.7 & 87.03–90.37 \\ focal motor seizures involving a limb & 211 & 65.7 & 63.05–68.35 \\ \hline Apnea attacks & 185 & 51.1 & 48.47–53.73 \\ \hline Impaired consciousness & 269 & 74.3 & 72.0–76.6 \\ \hline Generalized movement disorders (hypotonia) & 243 & 67.1 & 64.63–69.57 \\ \hline Tremors & 169 & 46.7 & 44.08–49.32 \\ \hline Resuscitation required & 142 & 39.2 & 36.63–41.77 \\ \hline Pathologic irritability & 99 & 27.3 & 24.96–29.64 \\ \hline Convergent strabismus & 93 & 25.7 & 23.4–28.0 \\ \hline \hline \end{tabular}
\end{table} 
Table 1: Clinical manifestations of ischemic stroke in newborns (Number of cases = 362), abs., %. head trauma (previously known as shaken baby syndrome) and may indicate intense pain [7]. Some infants also displayed additional manifestations such as rotatory nystagmus (6.07%) and leg clonus (5%). Consequently, newborns present clinical signs reminiscent of various central nervous system disorders, necessitating a thorough differential diagnosis. These events, documented in the neonatal period, are closely linked to cognitive and/or motor outcomes in childhood, often resulting in varying degrees of disability. The logistic regression analysis revealed a significant association between clinical symptoms and the child's age. Specifically, epileptic seizures (\(p<0.001\); RR = 5.118), impaired consciousness (\(p=0.006\); RR = 2.909), generalized movement disorders (\(p=0.004\); RR = 3.963), and apnea attacks (\(p=0.002\); RR = 2.861) were identified as the most significant suggestive symptoms for diagnosing ischemic strokes in newborns. The clinical presentation of childhood stroke varies depending on factors such as age, developmental characteristics of the central nervous system, affected artery, and the underlying cause of the disease. To account for these variations, the clinical manifestations of IS were evaluated in 148 children aged between 28 days and 18 years. They were categorized according to the stages of child development: infants (28 days-1 year), young children (1-3 years), preschoolers (4 years-6 years), schoolchildren (7-12 years), and adolescents (13-18 years), with grouping based on similarities of IS clinical symptoms to those observed in adults (Figure 1). logical deficits that may go unnoticed by parents and doctors, such as reduced one-sided body strength, preferential use of one hand, fist clenching or leg clonus, psychomotor agitation, mainly focal epileptic seizures, as well as respiratory and consciousness disorders in severe cases. The clinical symptoms in young children (from 1 to 3 years old) are characterized by slight focal neurological deficits such as hemiparesis, focal movement disorders, and one-sided body weakness. Motor deficits often manifest on one side of the body, more commonly on the right, followed by injury to the left cerebral hemisphere. Other predominant symptoms include focal epileptic seizures, impaired consciousness, psychomotor agitation, and less commonly, coordination disorders, tremor, nystagmus, impaired eyesight, and vomiting. Children over three years of age may present the following clinical manifestations: focal neurological deficit, commonly followed by hemiparesis, less often by hemiplegia, focal epileptic seizures, mental disorders, headaches, and agitation. Less common symptoms observed are ataxia, nystagmus, dizziness, hemianopia, and speech disorder. Based on the child's age, disease onset, clinical symptoms, and imaging findings, neurological examination results suggested significant logistic regression outcomes. Moreover, the data analysis, modeling the relationship between a series of independent variables and a dichotomous dependent variable, identified the most important suggestive symptoms for diagnosing IS, depending on the child's age.