### Carrier Peptides  
The last type of peptide is carrier peptides, and in this case we will look at the copper peptide hidden in cosmetology under the name Copper Tripeptide-1. Gly-His-Lys (GHK, matricryptin) is the biological name of the tripeptide isolated from human plasma, showing a strong affinity for copper (II) ions, with which it forms a complex (GHK-Cu) spontaneously. Initially, it was identified as a growth factor for various mature cells, but more recent studies indicate its physiological role in wound healing and tissue regeneration. GHK-Cu directly supports wound healing and stimulates biological processes essential for tissue repair, such as angiogenesis, nerve development, and chemoattraction of key cells for the healing process (e.g. macrophages, monocytes, mast cells, capillary endothelial cells) [24]. [PERSON] et al. reported that GHK-Cu stimulates collagen synthesis in cultured fibroblasts, independent of the action of growth factors [25]. The presence of the GHK sequence in the \(\alpha\)I(I) chain of human collagen suggests that this tripeptide may be released during the collagen production process. It is also very helpful in the wound healing process, where it supplies copper for matalloproteinase, hence its classification as a carrier peptide [6]. The copper peptide was initially confused with a growth factor, but [PERSON] et al. demonstrated that it has a stimulating effect on fibroblasts [26; 27]. It reduces reactive  
Figure 2: Chemical structure of agireline. Acetyl and amide groups are marked red. oxygen species (ROS) production, increases superoxide dismutase (SOD) activity while decreases TNF-\(\alpha\) and IL-6 production through the suppression of NF-\(\kappa\) B, p65 and p38 MAPK signaling [28]. The tripeptide has been also subject to modification. Pal-GHK stimulates fibrillogenesis probably by activity on TGF-\(\beta\)[8]. Biotinyl-GHK is also capable of binding copper [29]. The proposed mechanisms of action refer to many compounds, and there are many more peptides, contained in preparations under registered names, as listed below, in alphabetic order [9; 19]:  
1. [noitemsep]
2. ActiMatrix: Peptide based mushroom Extract;
3. Actimp 1.9.3: Hydrolyzed Lupine Protein
4. Adifyline: Acetyl Hexapeptide-38
5. Aldenine: Hydrolized Wheat Protein, Hydrolized Soy Protein, Tripeptide-1
6. Ascotide: Ascorbyl Phosphate Succinoyl Pentapeptide-12
7. BeauActive MTP: Hydrolyzed milk protein
8. Bio-Bustyl: Rahnella Soy Protein Ferment, Palmitoyl Oligopeptide
9. Biopeptide CL: Palmitoyl Oligopeptide
10. BONT-L-Peptide: Palmitoyl Hexapeptide-19
11. Caspaline 14: Hexapeptide-42
12. ChroNOgen: Tetrapeptide-26
13. ChroNOline: Caproyl Tetrapeptide-3
14. Colhibin: Hydrolyzed Rice Protein
15. Collaxyl: Hexapeptide-9
16. Cytokino: Hydrolyzed Casein, Hydrolyzed Yeast Protein
17. Decorinol: Tripeptide-9 C citrulline
18. Decorinyl: Tripeptide-10 Citrulline
19. Deepaline: Palmitoyl hydrolyzed Wheat Protein
20. Delisens: Acetyl Hexapeptide-46
21. DermanPeP A350: Myristol Tripeptide-31
22. DermanPeP A420: Myrristoyl Tetrapeptide-6
23. Derman: Acetyl Tetrapeptide-9
24. dSlayer: Lysine HCl, Lecithin, Tripeptide-9 Citrulline
25. Diffuporine: Acetyl Hexapeptide-37
26. Drieline: Yeast Betaglucan
27. Dynachondrine ISR: Hydrolized Soy Protein
28. ECM Moduline: Palmitoyl Tripeptide-28
29. ECM Protect: Tripeptide-2
30. Effipulp: Hydrolyzed Avocado Protein
31. Elhibin: Glycine Soja Protein
32. Extracellular: Hydrolyzed Potato Protein
33. Eyeseryl: Acetyl Tetrapeptide-5
34. Granactive AGE: Palmitoyl Hexapeptide-14
35. Inyline: Acetyl Hexapeptide-30
36. IP 2000: Trifluoracetyl Tripeptide-2
37. Juvefoxo: Acetyl Hexapeptide-50
38. Kollaren: Tripeptide-1
39. Laminixyl IS: Heptapeptide
40. Leuphsyl: Pentapeptide-18
41. Liftline: Hydrolyzed Wheat Protein
42. Lipacide PVB: Palmitoyl hydrolyzed Wheat Protein
43. Lipeptide: Hydrolized Vegetable Protein
44. Marine Filling Spheres: Atelocollagen
45. Pentacare-NA: Hydrolyzed Wheat Gluten
46.