## Results
### Moderator Analysis
ub \({}^{\bf 6}\)** & **R\({}^{\bf 2}\) (\%)** \\ \hline \multirow{10}{*}{ZO\(-1\)} & Intercept & \(6.9744\) & \(2.8378\) & \(0.0140\)\({}^{\bf*}\) & \(1.4124\) & \(12.5364\) & \\  & B. _bree_ & \(-3.0068\) & \(3.8836\) & \(0.4388\) & \(-10.6185\) & \(4.6049\) & \\  & B. _fragilis_ & \(-4.4113\) & \(3.2109\) & \(0.1695\) & \(-10.7046\) & \(1.8819\) & \\  & B. _infantis_ & \(-0.1449\) & \(4.1975\) & \(0.9725\) & \(-  
\begin{table}
\begin{tabular}{c c c c c c c c} \hline \hline
**Item 1** & **Subgroup** & **Estimate** & **SE 3** & \(p-\)**Value 4** & **Cl. lb 5** & **Cl. ub 6** & **R2 (\%)** \\ \hline  & Intercept & 8.6724 & 3.3722 & 0.0101 * & 2.0631 & 15.2817 \\  & B. _breve_ & \(-3.6635\) & 4.6024 & 0.4260 & \(-12.6841\) & 5.3571 \\  & B. _fragilis_ & \(-5.6702\) & 3.8086 & 0.1365 & \(-13.1349\) & 1.7945 \\  & B. _infantis_ & 8.7071 & 6.2667 & 0.1647 & \(-3.5755\) & 20.9896 \\  & B. _longtime_ & \(-3.6720\) & 4.6995 & 0.4346 & \(-12.8829\) & 5.5389 \\  & B. _subtilis_ & \(-7.1787\) & 4.5800 & 0.1170 & \(-16.1552\) & 1.7979 \\  & C. _butyricum_ & \(-3.4568\) & 4.2446 & 0.4154 & \(-11.7760\) & 4.8624 \\  & E. _Coli_ Nissle & \(-6.0720\) & 4.0014 & 0.1291 & \(-13.9146\) & 1.7706 \\  & L. _case_ & \(-3.7033\) & 3.8745 & 0.3392 & \(-11.2972\) & 3.8905 \\  & L. _ferrument_ & \(-3.9842\) & 4.5919 & 0.3856 & \(-12.9841\) & 5.0158 \\  & L. _gasseri_ & \(-4.8758\) & 3.8509 & 0.2055 & \(-12.4234\) & 2.6719 \\  & Probiotics & L. _johnstini_ & \(-7.6132\) & 4.5017 & 0.0908 & \(-12.4234\) & 2.6719 \\  & Probiotics & L. _lactis_ & \(-2.0662\) & 3.7498 & 0.5816 & \(-9.4157\) & 5.2833 \\  & strain & L. _paracasei_ & \(-6.8846\) & 4.5278 & 0.1284 & \(-15.7589\) & 1.9897 \\  & L. _platarium_ & \(-4.4105\) & 3.5894 & 0.2192 & \(-11.4457\) & 2.6247 \\  & L. _retretri_ & \(-3.6473\) & 4.6628 & 0.4341 & \(-12.7863\) & 5.4916 \\  & L. _transous_ & \(-4.8075\) & 3.8655 & 0.1922 & \(-12.0329\) & 2.4179 \\  & L. _sakeri_ & \(-7.5784\) & 3.6865 & 0.1922 & \(-12.0329\) & 2.4179 \\  & L. _salitarius_ & \(-5.5702\) & 4.5498 & 0.2208 & \(-15.4050\) & 0.2481 \\  & Medicine & \(-6.9143\) & 3.6598 & 0.0589 & \(-14.0873\) & 0.2587 \\  & Mixed culture & \(-2.6412\) & 3.5224 & 0.4534 & \(-9.5450\) & 4.2625 \\  & Prebiotics & \(20.7735\) & 8.6211 & 0.0160 * & 3.8766 & 3.6705 \\  & _S. thermophiles_ & \(-5.7126\) & 4.5623 & 0.2105 & \(-14.6545\) & 3.2293 \\  & _Sheuemella_ sp. & \(3.2302\) & 5.1308 & 0.5290 & \(-6.8260\) & 13.2863 \\  & Synbiotics & \(4.7622\) & 4.6464 & 0.2105 & \(-14.6545\) & 3.2293 \\  & _Syntechococcus_ & \(-5.7857\) & 4.5603 & 0.2045 & \(-14.7238\) & 3.1524 \\ \hline Administration & Intercept & 6.6502 & 2.0584 & 0.0012 & 2.6159 & 10.6846 \\ time & Day & \(-0.0111\) & 0.0771 & \(-0.1444\) & 0.8852 & \(-0.1623\) & 0.00 \\ \hline Dosage & Intercept & 30.9506 & 13.2133 & 0.0192 & 5.0530 & 56.8463 \\  & Dosage & \(-2.5663\) & 1.3829 & 0.0635 & \(-5.2768\) & 0.1441 \\ \hline  & Intercept & 6.9744 & 2.8378 & 0.0140 * & 1.4124 & 12.5364 \\  & B. _breve_ & \(-3.0068\) & 3.8836 & 0.4388 & \(-10.6185\) & 4.6049 \\  & B. _fragilis_ & \(-4.4113\) & 3.2109 & 0.1695 & \(-10.7046\) & 1.8819 \\  & B. _hatitis_ & \(-0.1449\) & 4.1975 & 0.9725 & \(-8.3718\) & 8.0820 \\  & B.