## 3 Results
### Results of Synthesis
#### 3.4.2 Cornea Preservation Qualitative Parameters  
Endothelial cell morphology was assessed in eight studies [13; 23; 25; 26; 29; 30; 31] by the methods of slit-lamp biomicroscopy [23; 26; 31], specular microscopy [26], and electron microscopy [20; 25; 26; 31] (Table 10). Three studies assessed the corneal transparency [13; 23; 30] (Table 10). The complete data characterizing the studies are provided in Tables 4, 9 and 10. Most studies reported no statistical difference in qualitative results (corneal transparency and EC morphology) [29; 30]. The comparative study conducted by [PERSON] et al., 2014 reported that Cornea Cold performed better than Optisol-GS, subjectively, for all parameters (\(p\) < 0.05) [13]. \begin{table}
\begin{tabular}{l l l l l} \hline \hline
**Author Year** & **Endothelial Cell (EC) Mortality (\%)-42\%** & **Endothelial Cell (EC) Mortality (\%) \(<\)2\%** & **Study Conclusion** \\
**Optical-CS** & **Distinct Media** & & \\ \hline [PERSON] and [PERSON], 2016 [22] & Optisol-CS & Cornised & This study concludes that CS is as effective as OS & This study concludes that CS is as effective as OS & for storing corneal tissues at 2-8 \({}^{\circ}\)C. \\  & Endothelial cell loss (\%) & Endothelial cell loss (\%) \(p=0.1563\) & & for storing corneal tissues at 2-8 \({}^{\circ}\)C. \\  & Day 3.7, \(l\) (\(n=31\)) & Day 3.3, \(p=0.979\) & & \\ Day 7: \(9.4\) (\(n=30\)) & Day 7: \(9.4\) (\(n=30\)) & Day 10: \(13.5\) (\(n=27\)) & & \\ Day 10: \(13.5\) (\(n=27\)) & Day 14: \(14.0\) (\(p=6.637\) & & \\ Day 14: \(15.7\) (\(n=19\)) & Day 14: \(17.4\) (\(p=8.024\) & & \\ \hline [PERSON] et al., 2020 [30] & Optisol-CS & Kerasawe with amphotericin B and Optisol. & Day 14, EC mortality (\(3.07\%\pm.093\%\) in Kerasawe and \(3.8\%\pm.07\%\) in Optisol-CS) was higher in & \\  & \(\times\)EC mortality (\(n=16\)) & \(\times\)EC mortality (\(n=16\)) & and \(3.38\%\pm.07\%\) in Optisol-CS) was higher in & \\  & Central ozone: & Central ozone: Day 14: \(0.54\), \(p=0.021\) & both groups as compared to the initial values & \\  & Day 14: \(0.14\), \(p=0.0029\) & Peripheral cornea. & (\(p=0.033\) for corneas in Kerasawe and \(p=0.002\) in Optisol-CS), it was comparable between groups & \\  & Payel 1: \(0.38\pm.020\) & Day 1: \(0.35\pm.034\), \(p=0.07\) & Optisol-CS), it was comparable between groups & \\  & Day 1: \(3.38\%\pm.020\) & Day 14: \(3.07\%\pm.035\), \(p=0.003\) & \(p=0.62\)). Day 14, the extent of mortality was & higher in the peripheral area of contrast has in the central area for both storage groups (\(p=0.021\) for Kerasawe and \(p=0.002\) for Optisol-CS), whereas it was comparable at the initial evaluation (\(p=0.17\) for Kerasawe and \(p=0.15\) for Grobis-CS). & \\ \hline [PERSON] et al., 2000 [31] & Optisol-CS & Chen medium & The two storage media did not differ with respect to & \\  & Cell loss (\%) (\(n=9\)) & Cell loss (\%) (\(n=9\)) & endothelial cell loss during storage or to the & \\  & After 21 days: \(5\pm 5\) & After 21 days: \(11\pm 10\), \(p=0.18\) & percentage of TUNEL-positive cells for keratocyte & \\ \hline \hline \end{tabular}
\end{table} 
Table 9: Endothelial cell (EC) mortality or loss.