## 4 Results and Discussion
### Reported Experiments  
In Table 3, the parameters utilized for validating the meal and insulin models are shown. The abbreviations in the column names are experiment number (Exp), carbohydrate grams in breakfast (B-CHO), carbohydrate grams in lunch (L-CHO), carbohydrate grams in dinner (D-CHO), insulin units at breakfast (B-u), insulin units at lunch (L-u), insulin units at dinner (D-u). In the first experiment, the default values for carbohydrate and insulin units are used. In the second experiment, carbohydrate grams are reduced to half, but the insulin units are left at their default values. In the third experiment, default values for carbohydrate grams are used, but the insulin dose is doubled, and in the last experiment, carbohydrate grams are reduced to half, and the insulin dose is doubled. Figure 5 shows a glucose concentration plot for a 5-day simulation for each experiment reported in Table 3. In Figure 5a, the maximum glucose peak is close to 195 mg/dL every day of the reported simulation. In contrast, in Figure 5b, the maximum glucose peak surpasses 175 mg/dL due to the reduction of carbohydrate intake. In Figure 5c, the same carbohydrate intake is used, but both prolonged and rapid insulin doses are doubled. It can be shown that glucose levels are lower when compared with the plot of experiment 1, and in Figure 5d, also the carbohydrate intake is reduced to half to validate both meal and insulin models. In both experiments (3 and 4), it can be shown for its corresponding plots that even a risk of hyperglycemia is present due to the high insulin dose. \begin{table} \begin{tabular}{c c} \hline
**Insulin Model** & \\ \hline Rapid effect insulin type & Lispro \\ Prolonged effect insulin Type & NPH \\ Rapid effect insulin units at breakfast & 2 \\ Rapid effect insulin units at lunch & 2 \\ Rapid effect insulin units at dinner & 2 \\ Prolonged effect insulin units at breakfast & 3 \\ Prolonged effect insulin units at dinner & 3 \\ \hline \multicolumn{2}{c}{**Exercise Model**} \\ \hline Intensity & Light \\ Duration & 10 min \\ Start time & 9:00 AM \\ Routine & Monday checked \\ \hline \end{tabular} 
\begin{tabular}{c c} **Insulin** \\ **Dossification** \\In Figure 6, a validation of the exercise models through the corresponding simulation plots are shown. In order to obtain the reported plots, the used exercise intensities are light, moderate, and heavy, and the exercise durations are 10, 30, and 90 min. The default values for grams of carbohydrate intake and insulin doses are used. In Figure 5(a), the simulation using 10 min of light exercise is shown. The value of the glucose peaks after exercise (at 9:00 AM) is close to 185 mg/dL, but using 30 min of light exercise, this is under 180 mg/dL (Figure 5(b)), and when using 90 min of light exercise, the glucose peaks is close to 175 mg/dL (Figure 5(c)). Similar behavior is shown when using the same duration but with moderate exercise (Figure 5(d)-f). The value of the glucose peaks after exercise (at 9:00 AM) is close to 175 mg/dL, and it is low when compared with the same peak obtained when using light exercise (180 mg/dL). Finally, this behavior remains when using heavy exercise (Figure 5(g)-i). For comparing exercise intensities, it can be shown from plots that the glucose peaks after 10 min exercise are: close to 175 mg/dL, and it is low when compared with the same peak obtained when using light exercise (180 mg/dL). Figure 5: Comparison of blood glucose plots generated by AEDMA application for several values of carbohydrate grams and insulin units. (**a**) Experiment 1. (**b**) Experiment 2. (**c**) Experiment 3. 185 mg/dL for light exercise, over 175 mg/dL for moderate exercise, and below 170 mg/dL for heavy exercise. Similar results are obtained for 30 and 90 min of exercise duration. In general, there are many applications, however, long-term prediction of glucose still remains a challenge [20].