The quality parameters (quality losses, antioxidant properties and enzyme activities) were evaluated at different time periods (from 7 to 21 days) at cold storage (1 \({}^{\circ}\)C) and shelf life (25 \({}^{\circ}\)C), comparing post-harvest treatments with methyl jasmonate and salicylic acid. As a general trend, both post-harvest treatments significantly decreased the quality loss of chilling injury and fruit decay on all dates. The antioxidant capacity and the phenolic patterns increased for both treatments at all dates, and almost all the antioxidant enzyme activities increased significantly on all dates for both treatments (except catalase activities, which decreased with the methyl jasmonate treatment). In conclusion, both methyl jasmonate and salicylic acid are useful and inexpensive techniques to maintain the apricot fruit quality in both cold storage and shelf life conditions [6]. The second step for the evaluation of the health potential of fruit vegetables is testing the product in an in vitro model. Usually, in this step the capacity of the fruit/vegetable extract is evaluated to limit the viability of pathological cells, or to protect the healthy cellsfrom an induced external stress. In this special issue, a study evaluating the effect of olive (_Olea europaea_ L.) vegetation water on human cells regarding its antioxidant properties and radical scavenger bioactivities was published. The study involved the treatment of two cell lines, human hepatocellular carcinoma and human keratinocytes, with two food supplements containing concentrated olive water in combination with 6% lemon juice or 70% grape juice, respectively. The first analysis of the extracts revealed that hydroxytyrosol was the most abundant polyphenol in both formulations, followed by tyrosol and oleuropein (for the olive-derived concentrate with lemon juice), and by proanthocyanidins and tyrosol (for the olive concentrate with grape juice). Both extracts were demonstrated to be effective antioxidants, also preventing the advanced glycation end product formation. In addition, preliminary data indicate that the administration of hydroxytyrosol through these hydrophilic matrices is better absorbed into the human body [7]. After the demonstration of the beneficial effects of fruit and vegetable consumption in in vitro models, the following step is the evaluation of the positive effects also in in vivo animal models. A trial on morbidity and mortality in the context of sepsis and septic shock on male Sprague Dawley(r) rats was presented in this special issue. In this study, a thiosulfinate-enriched _Allium sativum_ extract was used as adjuvant in the management of sepsis induced by intraperitoneal _Escherichia coli_ ATCC 25922 inoculation. To evaluate the efficacy in the sepsis-induced management, clinical, analytical, microbiological and histopathological parameters were evaluated in the control group, in the group treated with antibiotic, and in the group treated with antibiotic plus _Allium sativum_ extract. The results confirmed that the utilization of _Allium sativum_ extract as an adjuvant to antibiotic treatment in the management of sepsis could improve the sepsis attenuation, ameliorating clinical parameters of rats as weight, ocular secretions, whiskers separation and physical activity level, inhibiting _Escherichia coli_ proliferation and thus, reducing overall mortality after an animal peritonitis model [8]. The final step for the valorization of the potential health benefits of fruit and vegetable consumption is the introgression of these products in the human diet. With this aim, two studies were published in this special issue. The first study involved a particular group of people affected by prediabetes mellitus, whose glucose levels did not meet the criteria for diabetes but were higher than those considered normal. These people were fed with two servings per day of _Gymura bicolor_, a red purple-colored vegetable, and the effect on glycemic control and antioxidant ability was evaluated.