## 3 Results
As shown in Figure 4, the chemiluminescence-rescence intensity during longer incubation periods (after 20 and 60 min) increased by 148% and 175%, respectively; however, only the latter value reached statistical significance (\(p<0.05\)). Figure 4: Maximum chemiluminescence intensity of a suspension of neutrophils after the addition of an IFN\(\gamma\) solution jointly or separately incubated with samples of HD Abs to IFN\(\gamma\). The samples contained: suspension of neutrophils—\(2.5\times 10^{5}\) cells; an IFN\(\gamma\) solution (10 ng/mL) incubated for 0, 20, and 60 min in the presence of HD Abs to IFN\(\gamma\) (hatched bar) or in the absence of HD Abs to IFN\(\gamma\) (white bar), which constituted 80% of the total sample volume; fMLF (2 uM); luminol (0.35 mM). Measurements were performed at 37 \({}^{\circ}\)C and pH 7.4; \({}^{\circ}\)\(p<0.05\) (in comparison with \"0 min\" for samples incubated with donor), \({}^{\circ}\)\(p<0.05\) (in comparison with \"0 min\" for samples incubated without donor). Changes in the Properties of Acceptor (0.5% Water-Alcohol Solution) after Joint Incubation with Donor (HD PMA) in CMF, as Well as with Aluminum Foil Shielding  
At the next stage, additional experiments were carried out, the purpose of which was to detect the presence of a distant effect of another HD sample, which was prepared on the day of the study and not in advance. The number of different joint incubation conditions was also increased. For this group of experiments, the donor sample (HD PMA) was prepared by us independently using the same technology of successive multiple dilutions as was used by OOO \"NPF \"MATERIA MEDICA HOLDING\" for the preparation of HD Abs to IFNy. The break-up of studies into preliminary and main with independent preparation of HD donor samples was a necessary condition that greatly increased the objectivity of the results, which describe the phenomenon of distant interaction of samples under CMF conditions. In particular, the absorption of atmospheric gases could have affected the results obtained in the preliminary experiments. Taking into account these circumstances, the conditions in the main group of experiments, performed on HD PMA, were adjusted in such a way that the comparison of the activity of the test samples was carried out relative to the control samples, which had also been incubated in the magnetic field for the same amount of time as the test samples as well as in closed cuvettes. The choice of PMA was due to its well-known activity in the neutrophil respiratory burst test as well as to its previously studied mechanism of action [21]. These experiments were combined with a study of the influence of an aluminum foil shield on the distant interaction between samples under CMF conditions. In these experiments, the samples were incubated in CMF for 60 min and the activity of both solutions was evaluated by cell chemiluminescence assay. If samples of HD PMA and 0.5% water-alcohol solution were jointly incubated in CMF (columns 3 and 4, Figure 5), then their ability to enhance the production of ROS by neutrophils increased approximately 2 times compared to their activity after they were incubated in CMF separately (columns 1 and 2). Figure 5: Maximum chemiluminescence intensity of a suspension of neutrophils after the addition of a 0.5% ethanol solution jointly or separately incubated with HD PMA samples with shielding. The samples contained: suspension of neutrophils—2.5 \(\times\) 10\({}^{5}\) cells; sample of 0.5% ethanol (white bar) or HD PMA (hatched bar) incubated for 60 min: separately (columns 1 and 2), jointly (columns 3 and 4), jointly, but the cuvettes are wrapped with foil on all sides (columns 5 and 6), jointly, but the cuvettes are wrapped with foil on all sides (columns 5 and 6), jointly, but the cuvettes are wrapped with foil on all sides (columns 7 and 8). are wrapped with foil on all sides, except for the side with which the two cuvettes were in contact (**columns 7 and 8**); fMLF (2 uM); luminol (0.35 mM).