## 4 Conclusions
123), Strasbourg, 18 March 1986; Appendix A. Guidelines for the Care of Laboratory Animals. Animal experiments were agreed to and approved by the Ethics Committee of the Izmerov Research Institute of Occupational Health. \begin{table}
\begin{tabular}{l c c c} \hline \hline  & \multicolumn{3}{c}{**Experimental Groups**} \\ \cline{2-4}
**Investigated Indicators** & **Control No 1** & **Control No 2** & **Main No 3** \\ \cline{2-4}
**Number of white blood cells (WBC), \(10^{9}\)/L** & \(19.3\pm 4.5\) \# & \(18.7\pm 14.1\) & \(14.7\pm 3.4\) * \\ Lymphocytes (LYM), \(10^{9}\)/L** & \(3.0\pm 1.0\) & \(3.4\pm 2.4\) & \(2.5\pm 0.8\) \\ Monocytes and eosinophils (MID), \(10^{9}\)/L** & \(6.0\pm 1.5\) & \(5.3\pm 2.8\) & \(4.7\pm 1.1\) * \\ Granulocytes (GRAN), \(10^{9}\)/L** & \(10.4\pm 3.3\) \# & \(9.3\pm 9.7\) & \(7.5\pm 2.0\) * \\ Erythrocytes (RBC), \(10^{12}\)/L** & \(8.4\pm 2.6\) & \(7.3\pm 1.3\) \# & \(6.4\pm 1.7\) \# \\ Hemoglobin concentration (HGB), g/L** & \(163.8\pm 43.1\) & \(143.5\pm 23.1\) & \(127.9\pm 28.6\) \# \\ Hematocrit (HCT), \% & \(37.6\pm 9.7\) & \(33.0\pm 4.3\) & \(29.4\pm 6.7\) \# \\ Average red blood cell volume (MCV), fl** & \(45.3\pm 2.8\) \# & \(45.4\pm 2.2\) \# & \(40.8\pm 15.3\) \\ Average hemoglobin content in erythrocyte (MCH), pg** & \(19.6\pm 1.2\) \# & \(19.6\pm 1.0\) \# & \(19.5\pm 3.2\) \\ \hline \hline \end{tabular}
\end{table} 
Table 4: Effect of the compared therapy regimens on the composition of rat peripheral blood (M \(\pm\) SD) on the 3 rd day. \begin{table}
\begin{tabular}{l c c c} \hline \hline  & \multicolumn{3}{c}{**Experimental Groups**} \\ \cline{2-4}
**Investigated Indicators** & \multicolumn{2}{c}{**Control \(\mathcal{N}\) 1**} & **Control \(\mathcal{N}\) 2** & **Main \(\mathcal{N}\) 3** \\ \cline{2-4}  & \multicolumn{3}{c}{**14 Days**} \\ \hline Number of white blood cells (WBC), \(10^{9}\)/L & 17.2 \(\pm\) 4.9 \# & 20.0 \(\pm\) 7.6 \# & 15.7 \(\pm\) 3.5 \\ Lymphocytes (LYM), \(10^{9}\)/L & 3.9 \(\pm\) 1.5 \# & 4.4 \(\pm\) 1.7 \# & 3.2 \(\pm\) 1.7 \\ Monocytes and eosinophils (MID), \(10^{9}\)/L & 7.1 \(\pm\) 1.7 \# & 7.4 \(\pm\) 2.6 \# & 6.1 \(\pm\) 1.1 \# \\ Granulocytes (GRAN), \(10^{9}\)/L & 6.2 \(\pm\) 2.7 & 8.2 \(\pm\) 4.3 & 5.8 \(\pm\) 2.9 \\ Erythrocytes (RBC), \(10^{12}\)/L & 7.7 \(\pm\) 1.9 \# & 6.9 \(\pm\) 2.3 \# & 7.6 \(\pm\) 1.9 \\ Hemoglobin concentration (HGB), g/L & 141.5 \(\pm\) 33.0 & 128.7 \(\pm\) 43.8 & 143.6 \(\pm\) 34.7 \\ Hematocrit (HCT), \% & 33.4 \(\pm\) 7.2 & 30.0 \(\pm\) 9.3 & 31.1 \(\pm\) 11.3 \\ Average red blood cell volume (MCV), fl & 44.1 \(\pm\) 3.1 \# & 43.8 \(\pm\) 2.4 \# & 44.1 \(\pm\) 1.8 \# \\ Average hemoglobin content in erythrocyte (MCH), pg & 18.6 \(\pm\) 1.2 \# & 18.7 \(\pm\) 1.1 \# & 18.8 \(\pm\) 0.8 \# \\ Average concentration of hemoglobin in erythrocyte (MCH), g/dL & 400.7 \(\pm\) 90.0 & 426.6 \(\pm\) 18.9 & 428.9 \(\pm\) 18.4 \\ Platelet count (PLT), \(10^{9}\)/L & 326.9 \(\pm\) 124.0 & 328.9 \(\pm\) 108.2 & 327.1 \(\pm\) 120.4 \\ Average platelet volume (MPV), fl & 9.3 \(\pm\) 0.3 & 8.9 \(\pm\) 9.2 & 9.2 \(\pm\) 0.3 \\ Platelet distribution latitude (PDW), fl & 7.8 \(\pm\) 2.3 & 8.9 \(\pm\) 7.5 & 8.3 \(\pm\) 1.0 \\ Plateletcrit, (PCT), \% & 0.3 \(\pm\) 0.1 & 0.2 \(\pm\) 0.3 \# & 0.4 \(\pm\) 0.1 \# \\ \hline \end{tabular}
\end{table} 
Table 6: Effect of the compared therapy regimens on the composition of peripheral rat blood (M \(\pm\) SD) on the 10 th day.