## 3 Results and Discussion
### The Antimicrobial Activity of Medicinal Plant Extracts  
The extracts with the highest values recorded in terms of TPC, TFC, and AA content for each analyzed medicinal plant were tested against 9 standard strains. Figure 9a-1 present the analyzed strains and the BIR (%) calculated according to formula 5 for the analyzed extracts. Figure 8: Linear correlations between AA, TPC, and TFC; linear and quadratic dependence of AA with respect to TPC and TFC. Figure 9: _Cont_. Regarding the antimicrobial effect of the MP extract (Figure 9a), the trend is positive and increasing with the tested concentration in the cases of _S. pyogenes_, _H. influenzae_, _S. flexneri_, _S. typhimurium_, _C. albicans_, _and_ C. _parapsilosis_. In the case of _P. aeruginosa_, it can be considered to have a positive trend correlated with the increase in MP concentration, but the results are negative, the tested concentration not being sufficient to reach the MIC. With increasing concentration, the reducing inhibition effect was observed when MP extract was applied against _S. aureus_ and _E. coli_. However, even at the minimum concentrations applied (15 mg/mL), a positive BIR is observed, which means that there is antimicrobial potential, but it does not increase when the concentration of the extract is higher. The results obtained in the case of TS extract (Figure 9b) highlighted a good antimicrobial effect, with a positive trend in the majority of tested strains and an average inhibition of around 65% in the maximum concentration tested. The best result was obtained against _E. coli_, where the BIR values ranged between 85.98-132.93%. In the case of _S. pyogenes_, the first two concentrations tested (15 and 30 mg/mL) showed negative BIR% results, but the concentration of 60 mg/MI TS in the extract led to a BIR% of 24.27%. The SO1 extract (Figure 9c) showed similar, positive antimicrobial efficacy against _S. aureus_, _E. coli_, _S. flexneri_, _H. influenzae_, _S. typhimurium_, and both strains of fungi, with maximum values between 59.25% and 73.79%. For all strains tested, the evolution is directly correlated with the increase in concentration of SO1 extract. The effectiveness of the sage extract was average in the case of _S. pyogenes_, with values varying between 21.84% and 31.55%. _P. aeruginosa_ showed negative results, although there was a positive trend in the first three tested concentrations; the concentration of 75% was the only positive value of 7%. Regarding the alcoholic extract of AM (Figure 9d), positive results were obtained against _H. influenzae_, _S. aureus_, _E. coli_, _S. flexneri_, _S. typhimurium_, _C. albicans_, and _C. parapsilosis_  
Figure 9: The antimicrobial activity of the extracts  
strains. _P. aeruginosa_ proved more resistant to the activity of the extract, with the BIR% values obtained varying between 3.05 and 18.29%. In the case of _S. pyogenes_, the trend is negative, with a value of 20.395% for a concentration of 15 mg/mL AM in the extract, a value that decreases to \(-\)39.32% BIR in the case of a concentration of 60 mg/mL. The antimicrobial effect of OV extract (Figure 9e) is good against _S. flexneri_, _S. aureus_, _E. coli_, _H. influenzae_, _S. typhimurium_, and the two strains of Candida. _S. pyogenes_ proved the first effective concentration at 30 mg/mL OV, and in the case of _P. aeruginosa_, only the highest concentration of 60 mg/L was effective with a BIR% of 3.05%. The EP extract (Figure 9f) showed above-average antimicrobial activity on most ATCC strains tested, with BIR% values that varied between 37.24% for the highest concentration of EP tested against _E. coli_ and 66.79% against _H. influenzae_. _P. aeruginosa_ showed MIC for the second concentration tested (30 mg/mL), the first concentration tested having a negative BIR% value (\(-\)32.93%). Regarding the antimicrobial activity of the HO extract (Figure 9g), _S. pyogenes_ was the most resistant, with a MIC value only proven at a concentration of 50% HO. At the maximum concentration, the BIR% obtained was 18.45%.