# Artificial Intelligence-Based System for Retinal Disease Diagnosis
## 3 Experimental Results
### RB-Classifier Testing
Particular attention should be paid to the age of 61-80 years, which is characterized by the presence of the diagnosis O2--age-related macular degeneration. The result of the simulation modeling indicates the presence of dry age-related macular degeneration. The fourth group. Here, the following combinations of input variable values I1, I2, I26, I36, I37 and I38 are varied:  
* I1 (age)--\"61-80\"; I2 (gender)--\"m\";
* I26 (mf-ERG, retinal density of the P component),
* I36 (mf-ERG, N1 amplitude), I37 (local ERG a-wave amplitude)--\"under normal\";
* I38 (local ERG a-wave latency)--\"above normal\". With this set of input variables, the result of simulation modeling is diagnosis O2 \"dry age-related macular degeneration\", the key influencing factors of which are age, gender and the results of local and multifocal ERG, which is confirmed by the study [29]. The fifth group. Here, the values of input variables I1, I3, I13, I17, I18, I23, I25, I26, I36, I37 and I39 are set:  
* I1 (age)--\"41-60\"; I3 (diabetes mellitus)--\"2\";
* I13 (cardiovascular pathologies)--\"yes\";* I17 (maximum ERG, peak latency of b-wave),
* I18 (maximum ERG, amplitude of a-wave),
* I25 (mf-ERG, latency of component P1),
* I39 (amplitude of b-wave of local ERG)--\"normal\";
* I23 (rod ERG, b-wave amplitude),
* I26 (mf-ERG, retinal density of the P component),
* I36 (mf-ERG, N1 amplitude),
* I37 (local ERG a-wave amplitude)--\"under normal\". With this set of input variables, the result of the simulation modeling is the diagnoses O2 \"wet age-related macular degeneration\", the key influencing factors of which are age and the results of local and multifocal ERG, and O1 \"non-proliferative diabetic retinopathy\", the occurrence of which in this experiment was influenced by such a key factor as the presence of type 2 diabetes mellitus. The sixth group. Here the values of the input variables I1, I3, I7, I14, I16, I19, I20, I26, I34, I36 and I37 are varied from the following ranges:  
* I1 (age)--\"41-60\"; I3 (diabetes)--\"1\";
* I9 (complaints of photopisa)--\"no\";
* I7 (difficulty reading),
* I14 (hereditary factor)--\"yes\";
* I16 (maximum ERG, b-wave amplitude)--\"reduced/not registered\";
* I19 (maximum ERG peak latency of a-wave)--\"norm\";
* I20 (cone ERG, a-wave amplitude),
* I26 (mf-ERG, retinal density of the P component),
* I34 (oscillatory potentials), I36 (mf-ERG, N1 amplitude),
* I37 (local ERG a-wave amplitude)--\"below normal\". The results of the simulation modeling are the diagnoses O1 \"non-proliferative diabetic retinopathy\", O2 \"age-related macular degeneration of the dry form\" and O3 \"hereditary retinoschisis (X-chromosomal)\". The result O1 \"non-proliferative diabetic retinopathy\" was determined by such factors as the presence of type 1 diabetes mellitus, reduced or undetectable amplitude of the b-wave ERG, as well as reduced oscillatory potentials, which is confirmed by the study [33]. The result O2 \"age-related macular degeneration dry form\" is influenced by age, the subjective indicator \"difficulty in reading\", as well as objective indicators of multifocal ERG and local ERG. The result O3 \"hereditary retinoschisis (X-chromosomal)\" was influenced by the hereditary factor, since this disease is inherited, as well as objective indicators, such as the amplitude of the a-wave of the cone ERG and the amplitude of the b-wave of the maximum ERG. Studies confirming the results of simulation modeling are described in [34]. The seventh group. In situations of this type, the values of the input variables I3, I4, I16, I18, I26, I33, I36 are changed from the following ranges:  
* I3 (diabetes mellitus)--\"2\";
* I4 (duration of diabetes mellitus, years)--\"5-10\";
* I16 (maximum ERG, b-wave amplitude)--\"reduced\";
* I18 (maximum ERG, a-wave amplitude),
* I26 (mf-ERG, retinal density of the P component),
* I33 (optic nerve lability),
* I36 (mf-ERG, N1 amplitude)--\"below normal\".