## 2 Case Report
By assessing the healing of the mandible through radiograph in the first 10 months, the progression of routine irrigation can be assessed, time for drain removal can be decided, the sign of early recurrence due to possible residual lesion can be monitored earlier, and finally, the next treatment step can be proceeded. Eight months after surgery, mandibular and maxillary arch impressions were created for fabrication of functional appliance, Frankel type, which was delivered to the patient one month later. The patient was instructed to wear the functional appliance for 19-20 h per day for myofunctional therapy to guide normal growth of the jaw (Figure 5a,b). In addition, appliance cleaning and oral hygiene maintenance was explained to the patient. Since the patient was in a growth period, regular adjustment of the functional appliance was required. Therefore, clinical and radiograph follow-up was performed at one month,  
Figure 3: Representative histopathological features. (**a**) Well-circumscribed, solid mass with a thin fibrous capsule. (**b**) Long, anastomosing cords of ameloblastic epithelium (arrowheads) in the fibrous stroma (H&E staining). Figure 2: Intraoperative and postoperative view. (**a**) The main mass of the tumor was identified after flap incision. (**b**) The obtained main mass of the tumor from the excision procedure; it can be seen that the cortical bone on the buccal part was already damaged by the tumor. (**c**) The excised gray-white mass 4.6 \(\times\) 3.1 \(\times\) 1.8 cm in size containing the permanent canine. (**d**) Post-operative panoramic view revealed the silastic drain inserted (arrowheads) for decompression after removal of the mass. (**e**)The clinical view of the drain (arrow) sutured along with the wound. and then on a trimonthly follow-up schedule. Follow-up comprised adjustment of the wire and acrylic components of the appliance and examination of the condition of the soft tissue surrounding the appliance, to observe signs of recurrence and to monitor the growth pattern (Figure 4d-g). The patient was cooperative and wore the functional appliance routinely for four years. At four years after surgery, the persistent #74, #75, and #85 teeth were extracted, and Augmentin 5 cc syrup was prescribed three times per day for three days. Routine follow-up was scheduled to assess eruption of teeth. Eight years after surgery, radiographic examination revealed no recurrence of the lesion and eruption of permanent teeth. Teeth #43 and #44 were missing due to the ameloblastoma and further orthodontic therapy and prosthodontic management are required (Figures 4h and 5c,d). Relevant data from this episode of care are organized as a timeline and presented in Figure 6.  
Figure 4: Monthly radiograph examination follow-ups. (**a**) Panoramic view revealed the condition of the lesion four days after surgery. The lesion looked slightly smaller than before surgery, in which the daily copious irrigation through drain (arrowheads) was provided for one week following surgery. (**b**) Four months of copious irrigation through drain (arrowheads) showed the increased radiopacity of the cavity. (**c**) The 10-month follow-up showed an increase of radiopacity intensity, with the border of the cavity merging with the surrounding healthy bone indicating bone formation at the previous lesion site. (**d**) The 19-month follow-up showed no sign of lesion recurrence. (**e**) The 40-month follow-up showed no sign of recurrence and exhibited improvement of anterior tooth alignment in the jaw. (**f**) The 48-month follow-up showed normal eruption of the right mandibular posterior teeth with no sign of recurrence. (**g**) The 58-month follow-up showed complete posterior left mandibular teeth eruption with no sign of recurrence. (**h**) The 8-year follow-up showed normal dental development with healthy bone density in the site of the previous lesion. Figure 5: Functional appliance therapy. (**a**) The upper view of the functional appliance, Frankel type.