###### Abstract  
Anthranilic acid analogues and their derivatives hold significant therapeutic potential for crafting designed compounds aimed at regulating cancer-causing pathways and addressing metabolic challenges linked to diabetes, antiviral agents [1], and biologically tolerant anti-inflammatory compounds [2, 3]. Anthranilic acid-based derivatives also have anticoagulant, antiallergic, antipyretic, diuretic, analgesic properties. Anthranilic acid serves as a precursor for crafting numerous commercial drugs and pharmaceuticals, playing a pivotal role as the foundational framework in various drug categories like fenamates and NSAIDs. Anthranilic acids and their derivatives have interesting antimicrobial, antiviral and insecticidal activities. Furthermore, the analogs of anthranilic acid and their derivatives act as initiators of apoptosis, suppressors of the hedgehog signaling pathway, blockers of the mitogen-activated protein kinase pathway, and inhibitors of aldo-keto reductase enzymes. Similarly, their antiviral characteristics emerge through the inhibition of HCV NS5B polymerase, while they exhibit antibacterial efficacy by blocking the UppS pathway. Additionally, anthranilic acid-derived \(\alpha\)-glycosidase inhibitors play a substantial role in diabetes management. The derivatives of anthranilic acid find applications in neuroprotection by downregulating pivotal pathways accountable for the expression of neuropathological traits and neurodegeneration. However, the transition metal compounds of anthranilic acid derivatives provide therapeutic possibilities in diabetes mellitus and obesity through the control of \(\alpha\)-glucosidase activity. Recently, [PERSON] et al. synthesized novel complexes using trifluorinated anthranilic acid derivatives [4]. The complexes' cytotoxic effects on A549 (human lung cancer cells) and Hela (human cervical cancer cells) were also investigated. Structural analysis through single-crystal X-ray crystallography revealed that all three complexes exhibit penta- or six-coordination of Co and Zn atoms, adopting a configuration of a twisted square pyramid or a triangular bi-conical geometry. A novel ligand [N-(4-chlorobenzoyl)-thiooxymethyl]anthranilic acid (CBA) was synthesized [5]. Numerous metal complexes of CBA with Mn, Co, Ni, Cu, Pd, Zn, Cd and Hg were obtained. New metal complexes of N-phenyl anthranilic acid were obtained with copper, nickel, and cobalt [6]. The ligand and its resulting complexes were subjected to testing against various bacterial species including _Shigella somaei_, _Klebsiella pneumoniae_, _Proteus vulgaris_, _Salmonella typhi_, and _Proteus mirabilis_, as well as _fungal species_ such as _Curvularis lunata_, _Aspergillus niger_, _Alternaria solani_, _Bipolaris spp._, and _Aspergillus fumigatus_. The results of the antimicrobial assessments suggest that the complexes exhibit higher activity compared to the ligand itself. A series of nano-sized anthranilic acid metal complexes were successfully synthesized and characterized, involving metals like Zn(II), Bi(III), Fe(II), Co(II), Cu(II), Mn(II), Al(III), Ni(II), and Cr(III) [7]. Additionally, their potential catalytic role in the reduction in 4-nitrophenol was investigated. These complexes, along with the free ligand, were subjected to testing against various plant pathogens encompassing bacteria, fungi, and nematodes. The metal complex with silver showed good antibacterial, antifungal and nematocidal activities. [PERSON] et al. documented the synthesis of ligands derived from anthranilic acid and phthalal anhydride, along with their corresponding metal complexes involving Cd(II), Co(II), Pb(II), and Cu(II) [8]. Furthermore, they assessed the antibacterial properties of these compounds. [PERSON] et al. successfully synthesized a new Schiff base through the reaction of piperonal and anthranilic acid [9]. They then prepared novel complexes involving Cu(II), Ni(II), Pb(II), Sn(II), and Mn(II) with this Schiff base.