# Nanoparticles Based-Plant Protein Containing
## 1 Introduction
In addition, carnosic acid, carnosol, and botulinic acid have been identified as the main anticancer agents in rosmary [12]. Camphor and alpha-pinene in this aromatic plant also have outstanding anti-cancer activities against breast and prostate cancer [12]. Rheumatic diseases, muscle pains, and migraines are used [13]. Also, rosmary increases \begin{table}
\begin{tabular}{c c c c c c} \hline
**No.** & **Chemical Compound** & **(\%)** & **No.** & **Chemical Compound** & **(\%)** \\ \hline
1 & \(\alpha\)-Thujene & 0.2 & 11 & P-Cymenene & 0.1 \\
2 & \(\alpha\)-Pinen & 18.7 & 12 & Linalool & 12.33 \\
3 & Camphene & 5.19 & 13 & Camphonel & 0.3 \\
4 & Verbenone & 0.8 & 14 & Camphor & 12.9 \\
5 & B-Pinen & 0.34 & 15 & Cis-Verbenole & 0.2 \\
6 & Myrcene & 1.07 & 16 & Iso-Pinocamphene & 0.1 \\
7 & 3-Carene & 0.04 & 17 & Borneol & 4.86 \\
8 & Limonene & 4.6 & 18 & Myrtenole & 1.2 \\
9 & 1,8-Cineole & 21.3 & 19 & Verbenone & 2.21 \\
10 & Trephine & 0.1 & 20 & \(\alpha\)-Humulene & 0.1 \\ \hline \end{tabular}
\end{table} 
Table 1: Chemical composition of rosmary essential oil [11]. blood circulation in the body and can be used to prevent hair loss and treat hair loss [12]. In traditional medicine, the aerial parts of rosmary are mainly used as an anti-inflammatory, headache and Abdominal pain, anti-spasm, arthritis, effects of gout, wound healing, diuretic, analgesic, anti-rheumatism, and anti-depressant are used [14]. Digestive disorders (as an anti-flatulent stimulant for the stomach and intestines), respiratory diseases (as an expectorant and disinfectant), heart pain (as a restorative and stimulant of heart arteries), anti-inflammatory and dizziness and memory enhancement [15]. Essential oil (EO) of plants is chemical compound with biological activities derived usually from the different parts of medicinal plants. Antibiotic, anticancer, antioxidant, antiparasitic, hypoglycemic, antihypertensive, and antifungal properties are the most important and most prominent biological properties of the natural essential oil of medicine plants [16; 17; 18; 19; 20; 21]. However, studies show that the use of plant EO faces several challenges [9]. The EOs are also called volatile oils or ether oils because they evaporate faster when air exposure than other oils. In addition, the targeted storage of plant EOs is another challenge in overcoming their potential therapeutic use. In the other hand, most of the plant essential oils are biologically unstable and insoluble in water and bind incompletely to the target sites. In addition, the targeted delivery of plant EOs is another challenge in overcoming their potential therapeutic use [21]. Based on this, it is necessary to discover new techniques to increase antimicrobial activity before using them for treatment. Currently, the common point of research is the study of the EO's composition, while more attention should be focused on solutions that enable the effective, safe, and direct use of these natural products. One of the most important methods is the use of nanoscience to formulate essential oils to increase the quality of the effect and prolong the biological activities. Encapsulation is a process in which solid, liquid and gas components are included in small capsules and their contents can be released at a controlled rate. Drug-carrying nanoparticles are made from materials such as plant polymers, synthetic polymers, and various materials. Polymeric NPs are one of the newest ways to apply natural essential oils [22]. Biopolymers are one of the types of NMs that are widely used in the pharmaceutical and food industries [22; 23]. Lately, NPs based on biopolymers have been widely used in drug delivery systems. In drug delivery systems, the rate of drug dissolution increases with increasing drug levels and associated carriers. Plant protein-based carriers have several advantages over animal lipids, proteins, or synthetic polymers due to their biodegradability, high drug-binding capacity, and availability [24; 25; 26].