## 6 Kiwi Bioactives in Cosmetics Applications
### Kivi Bioactives and Skin Health
#### 6.2.1 Phenolic Compounds
\begin{table}
\begin{tabular}{c c c c c} \hline \hline
**Bioactive** & **Potential Functional** & & **Activity** & **References** \\
**Compounds** & **Cosmetic Product** & & & **-** \\ \hline \multirow{6}{*}{\begin{tabular}{c} Phenolic compounds \\ \end{tabular} } & \multirow{6}{*}{\(\bullet\)} & \multirow{6}{*}{\begin{tabular}{c} Sunscreens and \\ sunblocks \\ \end{tabular} } & \multirow{6}{*}{\(\bullet\)} & Antioxidant and photoprotective properties against & [96; 97; 98; 99] \\  & & & UV (UVR, UVA, and UVB) radiation & \\  & & & Improvement to skin density, reduction of wrinkles, & [96; 100; 101; 102] \\  & & & increase in skin elasticity, hydration, and antiaging & [44; 103; 104; 105; 106] \\  & & & Expedited healing process & & [44; 103; 104; 105; 106] \\  & & & Control of overexposure to oxidative stress in the & [44; 103; 104; 105; 106] \\ \hline \multirow{6}{*}{\begin{tabular}{c} Vitamin C \\ \end{tabular} } & \multirow{6}{*}{\(\bullet\)} & \multirow{6}{*}{\begin{tabular}{c} Anti-hyperpigmentation, \\ wound and scar healing \\ formulations \\ \end{tabular} } & \multirow{6}{*}{\(\bullet\)} & Antioxidant and anti-inflammatory activities, with & [107] \\  & & & wound healing properties & \\  & & & Shielding against UV-induced oxidative stress, & [108; 109] \\  & & & providing regenerative benefits & [108; 109] \\  & & & Enhancement of aged skin’s microstructure attributed & [108; 109] \\  & & & to increased collagen synthesis & [108; 109] \\  & & & Capacity to address hyperpigmentation & [108; 109] \\ \hline \multirow{6}{*}{\begin{tabular}{c} Vitamin E \\ \end{tabular} } & \multirow{6}{*}{\(\bullet\)} & \multirow{6}{*}{\begin{tabular}{c} Photoprotective and \\ antioxidant formulations \\ \end{tabular} } & \multirow{6}{*}{\(\bullet\)} & Antioxidant, anti-tumorigenic, and photoprotective & [110] \\  & & & activities, with skin barrier stabilizing properties & \\  & & & Reduction of DNA damage and keratinocyte death in & [110] \\  & & & sunburn & \\  & & antioxidant formulations & & Enhancement of stratum corneum hydration & [110] \\  & & & Diminishes skin roughness & \\  & & & Protection against skin aging, due to its excellent & [111] \\  & & & moisturizing properties & \\ \hline Vitamin C and & \multirow{6}{*}{\(\bullet\)} & \multirow{6}{*}{\
\begin{tabular}{c} Stabilized antiaging \\ action \\ \end{tabular} } & \multirow{6}{*}{
\begin{tabular}{c} Entanglement of sunscreen in preventing DNA \\ damage and inflammation, promoting cell renewal \\ \end{tabular} } & \multirow{6}{*}{[109]} \\  & & & Strong antioxidant and anti-glycosylation properties & [112] \\  & & & Collagen degradation protection potential & [112] \\  & & & Boosting cell proliferation and reducing & [112] \\  & & regeneration. Collagen & oxidative stress & \\  & & and elastin stimulatory & \\  & & formulation & & Microprotection against UV radiation, increasing & \\  & & & microcirculation, diminishing skin roughness, & \\  & & & protection against skin cancer, and prevention of skin & [113; 114] \\  & & & aging and cell damage & \\ \hline \hline \end{tabular}
\end{table} 
Table 5: Bioactive compounds in kiwi fruit and its by-products with potential health-promoting applications in cosmetics. They can act as photoprotectants, since they protect the skin from photo-aging and photo-oxidative damage induced by UV radiation, including UVR, UVA, and UVB [96; 97; 98; 99]. Some substances have also been found to improve the density of the skin, they can reduce wrinkles and increase skin elasticity, as well as moisturize it, promoting an antiaging effect [96; 100; 101; 102]. Additionally, there is evidence from several experiments on rats that show the wound-healing effects of kiwi. A dressing that contained kiwi fruit paste was placed on inflicted burn wounds. The dressing moisturized the wounds and, since kiwi fruit extracts are rich in antibacterial agents and enzymes, it allowed the enzymes to digest the hard eschar in full-thickness burns, making the healing process faster than normal (Table 6) [103; 104; 105; 106].