## Appendix A Test and Questionnaires  
This section describes the tests and questionnaires used in the study. These are the following:  
* The University of Pennsylvania Smell Identification Test (UPSIT) is a standardized test used to evaluate a person's sense of smell. It consists of 40 microencapsulated odorants embedded in a \"scratch and sniff\" booklet. The subject must identify each odorant from a list of four possible choices. * The Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) is a clinical tool used to assess the motor and non-motor symptoms of PD. It consists of four parts: Part I evaluates non-motor experiences of daily living, Part II assesses motor experiences of daily living, Part III is a motor examination, and Part IV evaluates motor complications related to treatment. * The Hoehn and Yahr (HY) scale is a system commonly used to describe the progression of PD based on the severity of symptoms. It classifies the disease into five stages, ranging from Stage 1 (unilateral involvement only) to Stage 5 (wheelchair-bound or bedridden unless aided). * The Rapid Eye Movement Sleep Behavior Disorder Screening Questionnaire (RBDSQ) is used to assess the presence and severity of the Rapid Eye Movement (REM) sleep behavior disorder (RBD), a condition characterized by the absence of normal muscle paralysis during REM sleep, leading to movements and behaviors during sleep that can be harmful. The RBDSQ consists of 10 questions related to RBD symptoms and behaviors, with a score calculated based on the responses. * The Epworth Sleepiness Scale (ESS) is a questionnaire used to assess a person's likelihood of falling asleep during various daily activities. The individual rates their likelihood of falling asleep in eight different situations on a scale of 0-3. * Autonomic (SCOPA-AUT) is a clinical assessment tool used to evaluate the severity of autonomic dysfunction in PD patients. It consists of 25 items assessing symptoms related to autonomic function, including cardiovascular, gastrointestinal, genitourinary, thermoregulatory, and pupil-lomotor functions. * The Hopkins Verbal Learning Test-Revised (HVLT-R) is a neuropsychological test used to assess verbal memory and learning abilities. It involves the presentation of 12 words over three learning trials, followed by a delayed recall trial after 20-30 minand a recognition trial where the patient identifies the previously presented words from a list that includes distractors. * The Benton Judgement of Line Orientation Test (BJLOT) is a neuropsychological assessment that measures an individual's ability to perceive and reproduce the orientation of lines in space. The test consists of 30 black-and-white illustrations of line pairs, with the individual asked to match the angles to one of several response options. * The Semantic Fluency Test (SFT) is a neuropsychological test that assesses a person's ability to produce words belonging to a specific category, such as animals or fruits. * Letter Number Sequencing (LNS) is a cognitive assessment test that evaluates an individual's working memory and attention. The examiner reads a series of alternating letters and numbers aloud, and the individual is then asked to repeat them back in numerical and alphabetical order. * The Symbol Digit Modalities Test (SDMT) is a neuropsychological test that assesses cognitive processing speed and attention. The subject is given a key that pairs specific numbers with corresponding abstract symbols. They are then presented with a series of symbols and asked to match each symbol to its corresponding number as quickly and accurately as possible within a fixed time frame. * The State-Trait Anxiety Inventory (STAI) is a psychological assessment tool used to measure anxiety in individuals. The inventory consists of two sets of 20 items each, measuring two different aspects of anxiety: State Anxiety, which refers to an individual's current feelings of anxiety, and Trait Anxiety, which refers to their general tendency to be anxious across different situations.