## 4 Discussion  
This systematic literature review addresses an important gap by reviewing the studies elucidating the utilization of eHealth devices in the context of transplant care. This review encompasses 60 articles, which collectively explore diverse facets, including different types of users engaging with digital health within the realm of transplant care, the barriers and benefits associated with digital health tools, and the process of developing digital health. Predominantly, the existing literature in this domain focused on the implementation of eHealth in transplantation; therefore, this review addresses the gap by demonstrating the multifaceted aspects entailed in the utilization and integration of eHealth in transplant care that received less attention in the literature. By systematically analyzing and interpreting findings from multiple studies, this review was able to highlight patterns, themes, and underexplored areas that contribute to a more holistic understanding. However, it is important to acknowledge that the insights presented in this review are based on secondary data from the included studies. While this approach is valuable for identifying trends and gaps, conducting empirical research would provide an opportunity to directly engage with eHealth users and stakeholders in transplantation care, offering richer, firsthand insights into their experiences, needs, and challenges. Future studies could build on the findings of this review by undertaking qualitative or mixed-methods research to address these areas in greater depth. In terms of the _users of eHealth tools_, this study identified two main groups of eHealth users: (1) patients, caregivers, and families [30; 37; 40; 73]; (2) transplant providers, clinicians, and pharmacists [10; 11; 23; 26; 34; 46; 47]. The findings indicate that both groups of users are connected through the shared goal of providing and receiving health care servicesfor transplant purposes. Health devices facilitate the seamless exchange of information between patients/families and healthcare providers [40; 46]. Patients can provide real-time health status and symptoms data, enabling healthcare providers to make informed decisions [39; 51; 52]. Health Information Technology (HIT) plays a crucial role in supporting these interactions by ensuring the integration of patient data across various touchpoints in the transplant journey [15; 24]. Interoperable electronic health records (EHRs) are essential for managing patient history, donor-recipient compatibility data, medication adherence, and post-transplant monitoring [15; 47]. Digital platforms further enhance engagement by enabling virtual health for follow-up care, patient portals for medication adherence tracking, and remote monitoring systems to detect early signs of organ rejection or complications [33; 47]. Given that transplant patients often have comorbid conditions such as diabetes, hypertension, or infections, HIT must also support comprehensive care by incorporating these diagnoses into treatment plans and facilitating collaboration between specialties [18; 47]. While most eHealth tools are designed as a single domain [37; 40; 48] through shared platforms, both parties can coordinate care more effectively. For instance, patients can schedule appointments, track medications, and share relevant data with healthcare providers, leading to more personalized and timely care [41; 44; 46; 48]. While most eHealth tools are designed for a single domain [37; 40; 48], shared platforms allow both patients and providers to coordinate care more effectively. Patients can schedule appointments, track medications, and share relevant data with healthcare providers, leading to more personalized and timely care [41; 44; 46; 48]. At the same time, HIT strengthens provider decision-making through real-time access to laboratory results, decision support tools for organ allocation and rejection risk assessment, and predictive analytics for graft survival.