## 6 Nano-Particles and Nano-Structures
\begin{table}
\begin{tabular}{p{113.8 pt} p{113.8 pt} p{113.8 pt} p{113.8 pt} p{113.8 pt} p{113.8 pt}} \hline \hline \multicolumn{1}{c}{**Monolith**} & \multicolumn{1}{c}{**Reaction**} & \multicolumn{1}{c}{**Temperature**} & \multicolumn{1}{c}{**Time**} & \multicolumn{1}{c}{**Nano-Particle**} & \multicolumn{1}{c}{**Reference**} \\ \hline \multicolumn{1}{c}{**Poly(BuMA-co-EDTA)**} & \multicolumn{1}{c}{Introduction of photo-grafted zones of monomers suitable for} & Room & & & \\ \multicolumn{1}{c}{**EDTAA) and**} & \multicolumn{1}{c}{amination, supporting AuNP immobilization. Dual function} & Temperature & N/A & 20 nm Au & [9] \\ \multicolumn{1}{c}{**poly(LMA-co-EDTA)**} & \multicolumn{1}{c}{monolith.} & \multicolumn{1}{c}{(RT)} & & & \\ \hline \multirow{6}{*}{**Poly(GMA-co-EDTA)**} & \multicolumn{1}{c}{For poly(STY-\(co\)-DVB) chlorosulfonic acid in dry} & 60, 60, 70, & 20 h & \multirow{2}{*}{65 nm Late} & \multirow{2}{*}{[28]} \\  & dichloromethane was used for sulfonation. For & & & & \\ \multicolumn{1}{c}{**poly(GMA-co-EDMA)**} & \multicolumn{1}{c}{poly(GMA-co-EDMA), sulfonation was performed in three} & & & & \\ \multicolumn{1}{c}{**and poly(styrene-co-)**} & \multicolumn{1}{c}{tethipalamine, (ii) thiobenzoic acid and triethylamine (thiol} & & & \\ \multicolumn{1}{c}{**DVB)**} & \multicolumn{1}{c}{groups were oxidized by pumping a solution of} & & & \\ \multicolumn{1}{c}{**vert-butyl hydroperoxide. (iii) Sodium sulfite and} & & & & \\ \multicolumn{1}{c}{**tetra-n-butylammonium hydroxide.**} & & & & \\ \hline \multicolumn{1}{c}{**Poly(BuMA-co-AMPS- \(co\)-EDMA)**} & \multicolumn{1}{c}{Co-polymerization of sulfonic acid group suitable for latex} & \multirow{2}{*}{RT} & \multirow{2}{*}{2 h} & \multirow{2}{*}{60 nm Late} & \multirow{2}{*}{[46]} \\  & nano-particle agglomeration. & & & & \\ \multicolumn{1}{c}{**Poly(BuMA-co-AMPS- \(co\)-EDMA)**} & \multicolumn{1}{c}{Co-polymerization of sulfonic acid group suitable for latex} & & & \\ \multicolumn{1}{c}{**poly(BuMA-co-AMPS- \(co\)-EDMA)**} & \multicolumn{1}{c}{Co-polymerization of sulfonic acid group suitable for latex} & & & \\ \multicolumn{1}{c}{**co-EDMA)**} & \multicolumn{1}{c}{Nano-particle agglomeration.**} & & & \\ \multicolumn{1}{c}{**poly(GMA-co-EDMA)**} & \multicolumn{1}{c}{Introduction of surface immobilized AuNPs via cystamine} & & & \\ \multicolumn{1}{c}{**poly(GMA-co-EDMA)**} & \multicolumn{1}{c}{and subsequent cleavage of the disulfide bond, to reveal} & & & \\ \multicolumn{1}{c}{**surface thiols. AuNP modification.**} & & & & \\ \hline \hline \multirow{6}{*}{**Poly(GMA-co-EDMA)**} & \multicolumn{1}{c}{Generation of quaternary ammonium for IONP} & \multirow{2}{*}{RT} & \multirow{2}{*}{N/A} & \multirow{2}{*}{19 nm iron oxide} & \multirow{2}{*}{[119]} \\  & immobilization & & & & \\ \hline \multirow{2}{*}{**Poly(EDMA)**} & \multicolumn{1}{c}{Preparation of AuNP modified extraction pipette tip, for glycoprotein selectivity.} & & & \\ \multicolumn{1}{c}{**Poly(GMA-co-EDMA)**} & \multicolumn{1}{c}{**Coupling of \(\alpha\)-glucosidase to AuNP modified monolith for**} & & & \\ \multicolumn{1}{c}{**PMME.**} & \multicolumn{1}{c}{**PMME.**} & & & \\ \hline \multirow{6}{*}{**Poly(GMA-co-EDMA)**} & \multicolumn{1}{c}{For AuNP immobilization, and functionalizing groups such as 3-mercapto propionic acid (CEC), 1-octadecanethiol} & \multirow{2}{*}{RT} & \multirow{2}{*}{N/A} & \multirow{2}{*}{15 nm Au} & \multirow{2}{*}{[131]} \\  & (RPLC), and sodium 2-mercaptoethanol sulfonate (SCX). & & & & \\ \end{tabular}
\end{table} 
Table 4: Reactions used in the preparation of nano-agglomerated polymeric monoliths.