## 3 Results and Discussion
### Estimation of Analytical Characteristics
In the investigation by [PERSON] et al., the authors [51] studied the mechanism of action of an anti-leishmaniosis drug with antimony compounds as the main components. Some molecules targeting antimony, trypanothione synthetase and trypanothone synthetase [52], are involved in this mechanism. Influencing the oxidative stress of bacteria also happens when antimony (III) blocks the reduction of the above-mentioned enzyme by NADPH and interacting with two catalytical cysteines (Cys52 and Cys57) in the active center [53]. \begin{table}
\begin{tabular}{c c c c c c c} \hline \hline
**N** & \ \begin{tabular}{c} **Heavy** \\ **Metal** \\ \end{tabular}  & **Sensing Unit** & **Detection Method** & \begin{tabular}{c} **LOD, Dynamic** \\ **Range** \\ \end{tabular}  & **Probe** & **Ref. ** \\ \hline
5 & \(\text{S}\text{S}^{3+}\) & Quercetin-5’-sulfonic acid & \begin{tabular}{c} Adsorptive stripping \\ voltammetric method \\ \end{tabular}  & \ \begin{tabular}{c} 3.6 pg/ml. (608) and \\ 1.6 pg/ml. (180s) \\ 1.0-5.0 ng/ml. \\ \end{tabular}  & \begin{tabular}{c} Tap water and a \\ commercial mineral \\ water \\ \end{tabular}  & [45] \\ \hline
6 & \(\text{A}\text{S}^{3+}\), \(\text{S}\text{S}^{3+}\) & AgNPs as a modifier & \begin{tabular}{c} Electothermal atomic \\ absorption spectrometry \\ \end{tabular}  & \ \begin{tabular}{c} As\({}^{3+}\): 0.022 ng/mL \\ \end{tabular}  & \begin{tabular}{c} Seawater and tap \\ water \\ \end{tabular}  & [9] \\ \hline
7 & \(\text{A}\text{S}^{3+}\), \(\text{S}\text{S}^{3+}\) & GNPs & \ \begin{tabular}{c} As\({}^{3+}\): 2.3 ng/mL \\ \end{tabular}  & \begin{tabular}{c} Seawater and tap \\ water \\ \end{tabular}  & [10] \\ \hline
8 & \(\text{S}\text{S}^{3+}\) & - & \ \begin{tabular}{c} Trap-flame atomic absorption \\ spectrometry \\ \end{tabular}  & \begin{tabular}{c} 0.75 ng/mL \\ 5.0-10.0 ng/mL \\ \end{tabular}  & Tap and mineral water & [46] \\ \hline
9 & \(\text{S}\text{S}^{3+}\), \(\text{S}\text{S}^{3+}\) & \begin{tabular}{c} EDTA and \\ pyridine-2,6-dicarboxylic acid for chelating reaction with Sb \\ \end{tabular}  & \begin{tabular}{c} Anion exchange \\ high-performance liquid \\ chromatography \\ \end{tabular}  & \ \begin{tabular}{c} Sb\({}^{3+}\): 0.5 ug/mL \\ Sb\({}^{3+}\): 0.8 ug/mL \\ 5-200 ug/mL. \\ \end{tabular}  & \begin{tabular}{c} Hot spring samples \\ from New Zealand \\ \end{tabular}  & [18] \\ \hline
10 & \(\text{S}\text{S}^{3+}\) & - & Electrothermal atomic absorption spectrometry & 0.45 ug/mL & Soils and alfalfa \\ \hline
11 & \(\text{S}\text{S}^{3+}\) & - & Hydride generation coupled to atomic fluorescence & 0.08 ug/mL & Soils and alfalfa \\ \hline
12 & \(\text{S}\text{S}^{3+}\) & - & \ \begin{tabular}{c} Multi-spring flow injection \\ analysis with hydride \\ generation-atomic fluorescence \\ \end{tabular}  & 0.25–250 ug/mL & \begin{tabular}{c} Soils and alfalfa \\ samples \\ \end{tabular}  & [8] \\ \hline
13 & \(\text{S}\text{S}^{3+}\) & - & \ \begin{tabular}{c} Multi-spring flow injection \\ analysis with hydride \\ generation-atomic fluorescence \\ \end{tabular}  & 0.08 ng/mL & \begin{tabular}{c} Hard drinking water, \\ filtered and diluted \\ lake water \\ \end{tabular}  & [13] \\ \hline
14 & \(\text{S}\text{S}^{3+}\) & - & \begin{tabular}{c} HSA activated \\ (TGA)-capped CdTe \\ quantum dot name-generator \\ \end{tabular}  & \ \begin{tabular}{c} detection \\ Fluorescence \\ \end{tabular}  & 0.294 ng/mL & \begin{tabular}{c} Artificial pond water, \\ spring water, sewage \\ \end{tabular}  & [47] \\ \hline
14 & \(\text{S}\text{S}^{3+}\) & - & \begin{tabular}{c} Atmospheric pressure glow \\ discharge atomic emission \\ spectrometry \\ \end{tabular}  & 0.14 ng/mL & Groundwater samples & [48] \\ \hline
15 & \(\text{S}\text{S}^{3+}\) & \ \begin{tabular}{c} Absorbance at 198 nm after \\ hydride generation \\ \end{tabular}  & \begin{tabular}{c} UV-visible molecular \\ absorption spectrophotometry \\ with diode-array detection \\ \end{tabular}  & 3-440 ug/mL & PVC sample & [7] \\ \hline
16 & \(\text{S}\text{S}^{3+}\), \(\text{S}\text{S}^{3+}\) & Pyrogallol red & \