# Gene Networks and Pathways Involved in _Escherichia coli_ Response to Multiple Stressors
## 3 Results
### Functional Categories Involved in E. coli Response to Multiple Stressors
\begin{table}
\begin{tabular}{c c c c c c c c c} \hline \hline \multirow{2}{*}{**Functional Category**} & \multirow{2}{*}{**Function Type**} & \multirow{2}{*}{**Names of Genes**} & \multirow{2}{*}{**Names of Genes**} & \multirow{2}{*}{**Notes**} & \multirow{2}{*}{**Notes**} & \multirow{2}{*}{**Notes**} & \multirow{2}{*}{**Notes**} & \multirow{2}{*}{**Notes**} & \multirow{2}{*}{**Notes**} \\  & & & & & & & & & \\  & & & & & & & & & \\ \hline \multirow{8}{*}{**Metabolic processes**} & Transfeses & 2 & _tusb_, _trlmB_ & \(\times\) & \(\times\) & \(\times\) & \(\times\) & \(\times\) \\  & Hydrolaseses & 2 & _ycaC_, _yliE_ & \(\times\) & \(\times\) & \(\times\) & \(\times\) & \(\times\) \\  & Amino acids biosynthesis and & 2 & _ilvM_, _fluB_ & \(\times\) & \(\times\) & \(\times\) & \(\times\) & \(\times\) \\  & metabolism & & & & & & & \\  & Oxidoreductase & 1 & _Ndh_ & \(\times\) & \(\times\) & \(\times\) & & \(\times\) \\  & Lipid metabolism & 1 & _pgpC_ & \(\times\) & & \(\times\) & \(\times\) & \(\times\) \\  & Starch and sucrose & 1 & _treF_ & \(\times\) & \(\times\) & \(\times\) & \(\times\) & \(\times\) \\  & metabolism & & & & & & & \\  & Secondary metabolites & 1 & _cadA_ & \(\times\) & \(\times\) & \(\times\) & \(\times\) & \\  & biosynthesis & & & & & & & \\ \hline \multirow{8}{*}{**Cellular response**} & DNA damage & 8 & _ycgB_, _blc_, _gadX_, _gadW_, _yyjl_, & & & & & \\  & Stress & 4 & _rmf_, _uspC_, _mysA_, _boLA_ & \(\times\) & \(\times\) & \(\times\) & \(\times\) & \(\times\) \\  & Oxidative stress & 1 & _grxA_ & \(\times\) & \(\times\) & & \(\times\) & \(\times\) \\  & Acid stress & 5 & _slp_, _ydeP_, _ygaC_, _ycgZ_, _mgrB_ & \(\times\) & \(\times\) & \(\times\) & \(\times\) & \(\times\) \\  & Osmotic stress & 1 & _osmB_ & \(\times\) & \(\times\) & \(\times\) & \(\times\) & \(\times\) \\  & Phosphate starvation & 1 & _psiE_ & \(\times\) & & \(\times\) & \(\times\) & \(\times\) \\  & Heat & 1 & _ldhA_ & \(\times\) & \(\times\) & & \(\times\) & \(\times\) \\  & Nitrogen starvation & 1 & _yeaG_ & \(\times\) & & \(\times\) & \(\times\) & \(\times\) \\ \hline \multirow{8}{*}{**Trasnport**} & Amino acid & 3 & _leuE_, _gltP_, _alaE_ & \(\times\) & \(\times\) & \(\times\) & \(\times\) & \(\times\) \\  & Sugar & 1 & _bglF_ & \(\times\) & \(\times\) & \(\times\) & \(\times\) & \(\times\) \\  & Iron & 2 & _fecl_, _ferD_ & \(\times\) & \(\times\) & \(\times\) & \(\times\) & \(\times\) \\  & Metal ion & 2 & _corA_, _mtA_ & \(\times\) & \(\times\) & \(\times\) & \(\times\) & \(\times\) \\  & Bacterial secretion & 1 & _gspO_ & \(\times\) & \(\times\) & \(\times\) & \(\times\) & \(\times\) \\  & Multidrug efflux & 1 & _entrD_ & \(\times\) & \(\times\) & \(\times\) & \(\times\) & \(\times\) \\  & Others & 3 & _tehA_, _yphS_, _ytfl_ & \(\times\) & \(\times\) & \(\times\) & & \(\times\) \\ \hline \multirow{2}{*}{**Cell adhesion and biofilm formation**} & & & \multirow{2}{*}{10} & _ychH_, _yhCN_, _yodD_, _bsS_, & & & & \\  & & & _ycff_, _ymgA_, _qgcZ_, _cnu_, & \(\times\) & \(\times\) & \(\times\) & \(\times\) & \(\times\) \\  & & & _tomB_, _ybfG_ & & & & & \\ \hline \multirow{2}{*}{**Transcription regulation**} & & & \multirow{2}{*}{4} & _eutR_, _yddm_, _mtR_, _dsdC_ & \(\times\) & \(\times\) & \(\times\) & \(\times\) & \(\times\) \\ \hline \multirow{2}{*}{**DNA repair**} & & & \multirow{2}{*}{5} & _recF_, _nrdE_, _nrdF_, _nrdH_, _nrdl_ & \(\times\) & \(\times\) & \(\times\) & \(\times\) & \(\times\) \\ \hline \multirow{2}{*}{**Motility**} & Formation and regulation & 1 & _fgL_ & \(\times\) & \(\times\) & \(\times\) & \(\times\) & \(\times\) \\ \hline \multirow{2}{*}{**Others**} & & & \multirow{2}{*}{3} & _bluf_, _sra_, _essQ_ & \(\times\) & \(\times\) & \(\times\) & \(\times\) & \(\times\) \\ \hline \multirow{2}{*}{**Uncharacterized proteins**} & & & \multirow{2}{*}{15} & _yqfa_, _ybfG_, _yhhA_, _ybgS_, & & & & \\  & & & _arpA_, _ygaE_, _ydfY_, _yaiY_, & & & & & \\  & & & _yebE_, _ydiE_, _yvjG_, _yiiX_, _ycjF_, & & & & & \\  & & & _yihF_, _yidX_ & & & & & \\ \hline \hline \end{tabular}  
* An \(\times\) denotes that half or more of the genes within a functional category are differentially expressed.  
\end{table}