These synthetic EDCs are widely distributed throughout the environment, with their highest concentration in water, though they are also present in air, soil, sludge, and sediments [24; 25; 26; 27; 28]. The principal sources of surface water contamination are industrial and urban sewage discharge effluents [29]. Conventional wastewater treatment plants, WWTPs, are usually ineffective at removing EDCs [30]. The typical concentration ranges of these pollutants in WWTP influents are as follows: 41.1-2466 ng/L of MeP, 47.4-5700 ng/L of PrP, 7.05-1602 ng/L of BuP [31], 321-951 ng/L of BP [13], 46.4-986 ng/L of BPA [32], and 49-98.9 ng/L of E [33; 34]. Various processes have been investigated for removing these EDCs, including adsorption by activated carbon, chemical advanced oxidation, chemical precipitation, and ozonation [35]. However, these treatments have drawbacks, such as low efficiencies when applied to real wastewater and high operational costs [36]. In this context, microalgae provide a promising solution for EDC elimination. Microalgae are photosynthetic, free-floating microorganisms capable of forming filaments and colonies. They exhibit a remarkable ability to adapt to extreme ecological habitats. Through cellular activities, microalgae convert light and carbon dioxide (CO\({}_{2}\)) into various specialised chemicals, including carbohydrates, proteins, lipids, vitamins, and pigments [37]. Compared to the previously mentioned processes, the microalgae-based removal of EDCs offers distinct advantages, including the ability to fix CO\({}_{2}\)[38] and the removal of nutrients from contaminated water [39]. Moreover, the biomass produced can be further processed for other uses, such as energy production [40]. The removal of EDCs using photosynthetic microorganisms can be driven through four main mechanisms: bioadsorption, bioaccumulation, biodegradation, and photodegradation [41]. The most crucial step in the bioremediation process is the selection of microalgae, as their removal capacity can be influenced by heavy metals or other contaminants in wastewater [42]. Although various genera can remove EDCs from wastewater, _Chlorella_ and _Scenedesmus_ are the most frequently reported in the literature [43; 44; 45; 46; 47; 48]. Another advantage of these two microalgae is that they can be isolated from WWTPs [49; 50; 51]. The existing literature includes several examples demonstrating the effectiveness of microalgae in removing EDCs. For instance, _Scenedesmus obliquus_ and _C. vulgaris_ have been shown to achieve removal rates of 99% for BPA, 87% for E, and 100% for both MeP and PrP within 7 days [52]. Additionally, _S. obliquus_ biodegraded 96.66 and 74.38% of 0.5 and 2 mg of BP-3/L, respectively, in 10 days [53]. Other studies have evaluated the elimination of EDCs using a consortium with different microalgae and cyanobacteria, such as _Anabena cylindrica_, _Chlorococcus_, _Spirulina platensis_, _Chorella_, _Scenedesmus quadricuala_, and _Anabaena_ sp., achieving approximately 80% removal within 6 days in an algae pond system [54]. Furthermore, _Chlamydomonas mexicana_ and _C. vulgaris_ can biodegradable 40% of BPA in 10 days [55]. However, all these studies primarily focus on eliminating one or two specific compounds or micropollutants within the same family, often with similar chemical structures [48, 56, 57, 58]. Consequently, there is still a lack of research on the simultaneous removal of mixtures of EDCs from different families using these microorganisms. Thus, the novelty of our work is aligned with this challenge as it is focused on developing a microalgae-based system for the simultaneous removal of EDCs from different families, aiming to provide new insights into this field, including the study of EDC fate. In this context, _C. vulgaris_ and _Scenedesmus_ sp. were cultivated to simultaneously remove EDCs (MeP, PrP, BuP, BP, BPA, and E) and nutrients from wastewater. The proposed system utilises microalgae to treat effluent from primary decantation, enabling the simultaneous removal of both nutrients and EDCs.