# Predictability of ClinCheck in Overbite Correction with Aligners: A Systematic Review
## 2 Materials and Methods
### Data Collection and Data Items  
Two calibrated reviewers ([PERSON] and [PERSON]) removed duplicate records from the database using Rayyan software (Qatar Computing Research Institute, Doha Quatar, [[https://www.rayyan.ai](https://www.rayyan.ai)]([https://www.rayyan.ai](https://www.rayyan.ai))). Then, they screened the records, first by title and then by abstract, excluding those that did not meet the eligibility criteria. For papers where the reviewers were uncertain, the full text was reviewed.  
All disagreements were discussed between the two primary reviewers ([PERSON] and [PERSON]). If consensus was not achieved, a third reviewer was consulted as arbitrator ([PERSON].)  
A structured data extraction table was developed to systematically record and analyze the key characteristics of each included study. The items reviewed were the following: authors and year of publication, study design, sample size, sex, age, aligner system, number of aligners, material, presence of second molars, presence of bite block, bite ramp and type of attachments, use of elastics or TADs, type of software used by the authors to extract the data, overbite, clinical references adopted by the author to measure the overbite, type of  
\begin{table}
\begin{tabular}{c p{284.5 pt}} \hline \hline
**Articles** & **Reason of Exclusion** \\ \hline
[31] & The authors analyze overbite in a heterogeneous sample considering patients who underwent extraction and genioplasty \\ \hline
[32] & The authors analyze extraction cases \\ \hline
[33] & Two of the 24 patients included in the sample underwent extraction of four premolars \\ \hline
[34] & Patients \textless{}18 years old are also analysed from a cephalometric perspective between T1 and T2, without considering the data provided by ClinCheck \\ \hline
[35] & Patients \textless{}18 years old and evaluation of deep bite in terms of the IMPA value \\ \hline
[16] & The authors consider only the value of intrusion and do not report overbite values \\ \hline
[36] & The authors evaluate the leveling of the Spee curve, but the overbite data is not analyzed \\ \hline
[37] & There is a loss of the sample at T3. At T1, 36 patients are analyzed, and at T3, only 14 remain. Additionally, there is no evaluation of overbite through ClinCheck (T2) \\ \hline
[38] & The study compares two groups, but it does not analyze the correction of overbite through the ClinCheck software (T2) \\ \hline
[39] & Cephalometric evaluation between two groups of patients treated with two different devices in hyperdivergent patients, without considering the correction of overbite through software (T2) in patients treated with aligners \\ \hline
[14] & The correction of overbite at T2 through ClinCheck is not considered \\ \hline
[13] & The correction of overbite at T2 through ClinCheck is not considered \\ \hline
[40] & The correction of overbite at T2 through ClinCheck is not considered \\ \hline
[41] & The correction of overbite at T2 through ClinCheck is not considered \\ \hline
[18] & The correction of overbite at T2 through ClinCheck is not considered \\ \hline
[42] & The authors compare whether there are differences between the ClinCheck software and Geomagic Control X software in predicting the correction of overbite in open-bite subjects. However, they do not analyze the actual correction after treatment (T3) \\ \hline
[43] & The correction of overbite at T2 through ClinCheck is not considered \\ \hline
[24] & The correction of overbite at T2 through ClinCheck is not considered in the comparison between a group of patients treated with fixed appliances and a group treated with aligners \\ \hline
[27] & The correction of overbite at T2 through ClinCheck is not considered \\ \hline
[44] & The correction of overbite at T2 through ClinCheck is not considered \\ \hline \hline \end{tabular}
\end{table}
Table 1: Articles and reason for exclusion.  
overbite, measure of overbite, skeletal pattern, treatment duration, aligners, and change regime (Table 2).  
\begin{table}
\begin{tabular}{c c c c c c c c} \hline \hline