## Appendix A
\begin{table}
\begin{tabular}{c c c c c c c c c} \hline \hline
**Plant** & **Phytocompounds** & **Binding Affinity** & **RMSD** & **H/C-H Bond** & **Bond** & **Hydrophobic Interaction** & **Alkyl Interaction** & **Pi-Sigma/ Cation Stacked Interaction** \\ \hline  & Chlorogenic acid & \(-6.1\) & 2.307 & PHE86, ASN196, & 4.34, 2.65, & ASN87, ILE97, & & \\  & Chlorogenic acid & \(-6.1\) & 2.307 & PHE86, ASN196, & 4.34, 2.65, & ASP198, GLY199, & & \\  & Chlorogenic acid & \(-6.1\) & 2.307 & ILE235 & 5.55 & TYPE200, GLY232, & & \\  & & & & & & ILE233, GLN234, & & \\ _M. specisa_ & & & & & & THR236 & & \\ _Korthi_ & Isoquercitrin & \(-6.4\) & 2.484 & ASN196, ILE233, & 6.26\({}^{\circ}\), 4.25, & LEU54, PHE86, & & \\  & Isoquercitrin & \(-6.4\) & 2.484 & GLN234, ILE235, & 4.43, 5.59, & ILE197, ASP198, & & \\  & Isoquercitrin & & & & ASN87\({}^{\circ}\) & 4.47 & GLY199, THR236 & & \\  & & & & ASN196, & & PHE86, ASN87, & & \\  & Rutin & \(-6.1\) & 2.149 & ASN196\({}^{\circ}\), & 3.79, 4.05\({}^{\circ}\), & ASP88, GLY199, & & \\  & R\(\ddot{\rm a}\)ttin & & & ASP198, & 3.85, 3.67\({}^{\circ}\), & GLY232, ILE233, & & \\  & & & & GLN234\({}^{\circ}\), ILE235 & 5.01 & THR236 & & \\ \hline \multicolumn{2}{c}{Kabasura kudineer} & & & & & & & & \\ \hline  & Acteoside & \(-7.3\) & 2.804 & PHE86, ASN87, & 4.45, 6.04, & & & \\  & Acteoside & \(-7.3\) & 2.804 & ASP88, ASN196, & 3.09, 4.34, & LEU54, YSP195, & & \\  & & & & ASP198, GLY199, & 3.47, 5.84, & THR236 & & \\  & Serratogenic acid & \(-6.8\) & 2.404 & ASP88, GLN234 & 4.33, 4.54 & - & - & - \\  & Verbascoside & \(-7.1\) & 1.904 & ASN87, ASP88\({}^{\circ}\), & 6.07, 3.99, & GLN52, PR085, & LEU54, & \\  & Verbascoside & \(-7.1\) & 1.904 & ASN196, ASN196, & 3.49, 4.04, & ILE235 & & \\  & & & GLN234 & 5.37, 473 & & & \\ \hline  & Apigenin & \(-6.5\) & 2.588 & ASN87, ASN196, & 5.13, 3.54, & PHE86, ASP88, & & \\  & 7-O-glucose & & & GLY199, & 3.65, 3.42, & ILE233 & & \\  & & & & GLN234, ILE235 & 3.95, 4.52 & PHE86, ASN87, & & \\ \(H.\)_aritciutta_ & & & & & ASP88, THR108, & & \\  & Cucurbitacin B & \(-6.2\) & 2.838 & GLN234, GLY199 & 3.34, 4.84 & THR114, ILE197, & & - \\  & & & & & ASP198, ILE233, & & \\  & & & & & ILE235, THR236 & & \\ \hline _A. panixulata_ & Neoandrographolide & \(-6.3\) & 1.466 & ASN87, ASN196, & 3.79, 4.2, & GLN52, ASP53, & \\  & Neoandrographolide & \(-6.3\) & 1.466 & GLN234, ILE235, & 5.13, 4.25, & LEU54, PHE86, & & ASP88 \\  & & PRO272\({}^{\star}\) & & 5.55 & THR236 & & \\ \hline  & Orientin & \(-6.2\) & 1.189 & ASN87\({}^{\star}\), ASP88, & 4.32, 421, & PHE86, ASN87, & & \\  & Orientin & \(-6.2\) & 1.189 & ASN196, ILE233, & 5.42, 4.98, & ASP198, GLY199, & ILE197 & - \\  & Orienta & & & ASN87, ASP88, & & & \\  & Vitexin & \(-6.2\) & 1.562 & GLN234, & 3.24, 3.52, & - & - & - \\  & & & & GLN234\({}^{\prime}\), & 4.21 & & \\  & & & & ILE235, ASP198 & & & \\ \hline _T. invlucente_ L. & Rutin & \(-6.4\) & 1.702 & ASP88\({}^{\star}\), ASN196, & 4.39, 2.93, & GLN89, ILE231, & LEU54, & \\  & & & & & ILE233, GLN234 & 4.48, 4.79 & GLY232, ILE235, & ILE197 & \\  & & & & & PRO272 & & \\ _T. coridifolia_ & Tinosporide & \(-6.1\) & 2.551 & ASN87\({}^{\star}\), ASP198, & PHE86, ASP88, & & \\  & & & GLY199, ILE233, & 4.50, 3.59, & ASN196, TYR200, & & \\  & & & & ILE235\({}^{\star}\) & 5.90 & GLN234 & & \\ \hline \hline \end{tabular} Note: * indicates the carbon-hydrogen bond.  
\end{table} 
Table 1: _Cont._ \begin{table}
\begin{tabular}{p{42.7 pt} p{42.7 pt} p{42.7 pt} p{42.7 pt} p{42.7 pt} p{42.7 pt} p{42.7 pt} p{42.7 pt} p{42.7 pt} p{42.7 pt}} \hline \hline
**Plant** & **Phytocompounds** & **Binding Affinity** & **RMSD (Å)** & **H/C-H Bond Interaction (Å)** & **Bond Length** & **Hydrophobic Interaction** & **Alkyl Interaction Interaction** & **Pi-Sigma/ Cation Stacked Interaction** \\ \hline B.1.617.2. S-Protein–RBD-Domain & & & & & & & & \\ \hline \hline \end{tabular}
\end{table} 
Table 2: Binding affinity, RMSD, and interacting residues of the screened phytocompounds against RBD domain.