###### Abstract  
The aim of this clinical study was to investigate and compare implant survival rates, marginal bone loss, and surgical and prosthetic complications of healthy patients and subjects affected by hypertension receiving full-arch implant-prosthetic rehabilitation. From January 2016 to November 2016, patients affected by total dentulism of one or both arches or severe impairment of residual teeth who needed full-arch implant-prosthetic rehabilitation and who had the absence of any systemic diseases or the presence of hypertension as a single pathology were randomly selected. According to the inclusion criteria, 39 patients were enrolled for this study. The sample was divided into two groups: A total of 18 patients were included in Group A (healthy patients), and 21 patients were included in Group B (patients affected by hypertension). No statistically significant difference in implant survival rates, marginal bone loss, and prosthetic complications were observed between Group A and Group B. Except for variable bleeding, the results of the Pearson's chi-square test and z-test at a 99% confidence level suggest that there is no statistically significant difference in clinical complications between the groups. Within the limitations of this study, full-arch implant-prosthetic rehabilitation could be a feasible option for treating patients with hypertension, provided that hypertension is compensated and controlled.  
hypertension; dental implants; immediate loading; systemic diseases +
Footnote †: journal: Medical  
pathway, which helps regulate blood pressure, although the specific impact on dental implant stability remains unclear and could be associated with potential effects on bone metabolism and wound healing [9].  
Considering the increasing average age associated with a higher incidence of systemic diseases, hypertension seems to be an emerging important factor in the management of totally edentulous patients undergoing implant-prosthetic rehabilitation [10; 11; 12].  
While there is no direct link between hypertension and dental implants, it is important for individuals with hypertension to take certain precautions before undergoing implant surgery. This is because high blood pressure can increase the risk of bleeding during and after surgery, which can affect the success of the procedure and the healing process [13; 14].  
In addition, several drugs applied as treatment, such as beta blockers, could cause dry mouth, which can increase the risk of dental implant failure [15; 16].  
Dry mouth can also increase the risk of developing gum disease and tooth decay, which can further compromise the success of dental implants [17].  
Therefore, before undergoing dental implant surgery, it is important for individuals with hypertension to have their blood pressure under control. They should work closely with their healthcare provider to manage their blood pressure and ensure that it is at a safe level for surgery [18; 19].  
In addition, individuals with hypertension may need to avoid certain medications, such as aspirin or other blood thinners, prior to surgery to minimize the risk of bleeding [20; 21].  
The aim of this clinical study was to estimate and compare implant survival rates, marginal bone loss, and surgical and prosthetic complications of healthy patients and hypertensive subjects receiving full-arch implant-prosthetic rehabilitation.