Oral biofilms consist of a high number of species of bacterial (approximately 700 species) and fungal (more than 100 species) origins [5; 6]. When the microbial balance is disturbed (due to a plethora of factors, including lack of hygiene, inappropriate diet, immunosuppression and many others), the overgrowth of pathogenic biofilms leads to the progression of caries and periodontal diseases. This increase in the biomass of dysbiotic biofilms may lead to inflammation of the oral cavity and to severe local infections, referred to as periodontitis and periimplantitis, as well as to tooth decay [6]. The biofilms formed by opportunistic pathogens, such as _Pseudomonas aeruginosa_, _Staphylococcus aureus_ and _Candida albicans_, may result in a spectrum of infections, which may not be only localized in the oral cavity or throat but may further spread to the respiratory system, lower parts of the alimentary tract and also, after crossing the blood-brain barrier, may lead to the infection of the human nervous system [7; 8; 9]. Overall, due to the complexity of the microbial communities and relatively high possibility of disturbing the host-microbe balance, oral infections affect more than 3 billion people around the world, and they are considered the chronic disease with the highest frequency of occurrence [10]. Therefore, the maintenance of oral hygiene and counter-acting ongoing inflammatory, microbe-caused infections are of pivotal importance regarding the maintenance of general human health. The prophylaxis and treatment of oral cavity infections include scaling, brushing and the use of topically administered antimicrobials (of an antiseptic nature). This procedure is also applied to fight ongoing infections caused by pathogenic biofilms. An antiseptic may be administered by, for example, gels, liquids or lozenges. Of note, the oral application of these measures also has an impact on the microbiota of the throat, which is a niche that neighbors the oral cavity. An example of a common throat pathogen is the Gram-positive bacterium _Str. pyogenes_ (group A), causing (among others) a disease referred to as streptococcal pharyngitis, also known as streptococcal sore throat or \"strep throat\". The spectrum of antiseptic which may be provided in the above-mentioned formulations is vast and includes, among others: chlorhexidine, polihexanide, cetylpyridinium chloride or ocetendiine dihydrochloride. The last-mentioned antiseptic substance is a bipyridine cationic antiseptic with a wide range of action, including on the cell walls of Gram-negative and Gram-positive bacteria, fungal species and specific viruses. The antimicrobial activity of ocetendiine (OCT) against cariogenic microorganisms (when OCT was provided in the form of mouth wash) has already been presented in earlier research, both in vitro and in vivo. In these analyses, performed by other research teams, the efficacy of OCT (in the applied setting) was indicated as being higher than the presently most common oral antiseptic, referred to as chlorhexidine [11; 12]. One reason behind the high activity of OCT is its non-specific action mechanism that relies on its interplay with the microbial cell wall/membrane, disturbances in its continuity, leaking of cytoplasm to the external environment and, inevitably, the death of the cell. It should be noticed that the eradicative potential of oral antiseptic depends not only on its mechanism of action, but also (and to a high extent) on the mode of administration. The formulation of the drug has a pivotal impact on its release and absorption. Regarding the matter discussed, the formulation referred to as lozenges is considered to provide (comparing to a liquid antiseptic) a greater control over drug concentration, a more stable therapeutic effect and, finally, a higher convenience of application and removal [13].