## 3 Criteria for and Types of Probiotics and Its Use in Foods
\begin{table}
\begin{tabular}{c c c} \hline \hline
**Batch** & **Reference** \\ \hline _Bifidobacterium bifidum_ & [55] \\ _Bifidobacterium longum_ & [55] \\ _Bifidobacterium infants_ & [55] \\ _Bifidobacterium adolescents_ & [55] \\ _Bifidobacterium breve_ & [55] \\ _Bifidobacterium animalis_ ssp. _lactis_ & [56] \\ _Weizmannnia coagulans_ (formerly _Bacillus coagulans_) & [57] \\ _Bacillus subtilis_ & [58] \\ _Presita flexa_ (formerly _Bacillus flexus_) & [58] \\ _Bacillus licheniformis_ & [58] \\ _Bacillus nojranensis_ & [58] \\ _Bacillus amyloliquefaciens_ 2 & [59] \\ _Propionibacterium freudenerichii_ ssp. _shermanii_ & [60] \\ _Propionibacterium acidipropionici_ & [61] \\ _Propionibacterium jensenii_ & [62] \\ _Propionibacterium thoeuti (jensenti)_ & [62] \\ _Leuconsoc mesenteroides_ & [63] \\ _Leuconostoc pseudamestreoides_ & [64] \\ _Leuconostoc lactis_ & [65] \\ _Lactococcus lactis_ ssp. _lactis_ (formerly _Streptococcus lactis_) & [44] \\ _Lactococcus cremoris_ (formerly _Streptococcus cremoris_) & [66]3 \\ _Pediococcus acidilactici_ & [67] \\ _Pediococcus pentosacaus_ & [68] \\ _Enterococcus faccuni_ & [69] \\ _Enterococcus faecalis_ & [45] \\ _Enterococcusurans_ & [69] \\ _Enterococcus lactis_ & [68] \\ _Bacteroides vulgatus_ & [70]4 \\ _Bacteroides dorei_ & [70]4 \\ _Faccalibacterium prausnitzii_ & [70]4 \\ _Prerotella copri_ & [70]4,5 \\ _Yeast_ & \\ _Saccharomyces cerevisiae var. boulandii_ & [71] \\ _Kluyveromyces marxianus_ & [72] \\ \hline \end{tabular}  
* This reference describes adding this probiotic within jelly candy enriched with grape seeds extract. 2 This probiotic was isolated from yogurt-flavored cultured beverage Yogu Farm(tm), 3 Although this reference stated that _Lactococcus lactis_ ssp. _cremoris_ was isolated from yogurt, other papers have described this bacterium as a probiotic.
* These new generation probiotics were found in homemade back-slopped ygours. 5 Although this bacterium has been associated with health benefits, an overabundance of this intestinal bacterium was associated with arthritis and intestinal mucositis.  
\end{table} 
Table 2: List of GRAS (generally recognized as safe) substances (viable probiotic, heat-killed microorganism, or spore preparation) that might be able to be used in yogurt or related products as of 30 October 2022. Taken from: [[https://www.cfsanappsexternal.fda.gov/scripts/fdfcc/?set=GRASNotices](https://www.cfsanappsexternal.fda.gov/scripts/fdfcc/?set=GRASNotices)]([https://www.cfsanappsexternal.fda.gov/scripts/fdfcc/?set=GRASNotices](https://www.cfsanappsexternal.fda.gov/scripts/fdfcc/?set=GRASNotices)) (accessed on 30 October 2022). \begin{table}
\begin{tabular}{c c c c} \hline \hline
**GRN Number** & **Substance (Beneficial Microorganism)** & **Notifier** & **Status 1** & **Date of Closure** \\ \hline
1065 & _Annaerobutyticum soelingensii_ CH106 & Caelus Health & Pending & \\
1063 & _Weissella cibaria_ CMU & OraPharm, Inc. & Pending & \\
1022 & _Streptococcus salivarius_ DB-B5 & Dose Biosystems & No questions & 8/22/2022 \\
1013 & _Lactobacillus rhamnosus_ DSM & Chr. Hansen’s, Inc. & No questions & 12/15/2022 \\  & 33156 (LGG) & Morinaga Milk Industry & No questions & 4/26/2022 \\
1003 & _Bifidobacterium longum_ subsp. & Co., Ltd. & No questions & 4/26/2022 \\  & _Bifidobacterium breve_ strain MCC1274 & Morinaga Milk Industry & No questions & 7/22/2022 \\
988 & _Lactobacillus fermentum_ LGI96 & Quorum Innovations & No questions & 3/28/2022 \\ \hline \hline \end{tabular}
\end{table} 
Table 1: _Cont._* [399] Preparation of _Bacillus coagulans_ strain GBI-30, 6086 spores