## 5 Discussion
Generally, two hypotheses are confirmed for the actions of these compounds by several authors, such as: the power to activate apoptosis in tumor cells and the power to disrupt the mitochondrial membrane potential [49; 50]. Finally, the in vitro antibacterial tests of the two essential oils did not show any activity, except the CSEO, which has an activity against the four bacterial strains _Corynebacterium_ sp., _Staphylococcus aureus, Klebsiella pneumoniae_ and _Pseudomonas aeruginosa_. These results have been proven by several authors who confirmed the absence of antimicrobial activities of species of the genera _Cymbopogon_ spp. and _Nepeta_ spp. [51; 52]. \begin{table}
\begin{tabular}{c c c c} \hline \hline
**Essential Oils** & **Investigator** & **Place** & **Major Constituents** \\ \hline \multirow{6}{*}{CSEO} & [PERSON] (1993) [31] & Jaisalmer (India) & Limonene (19.54\%) and \\  & & & 2-undecanone (14.68\%) \\ \cline{2-3}  & [PERSON] et al. (2005) [32] & Kozah (Togo) & Piperitone (61.01\%) and Carene-2 (23.4\%) \\ \cline{2-3}  & [PERSON] et al. (2012) [33] & Sao Paulo (Brazil) & Geraniol (59.42\%) and Geraniol (13.49\%) \\ \cline{2-3}  & [PERSON] et al. (2020) [34] & Bechar–Ghardaa (Algeria) & Cis-p-menth-2-en-1-ol (22.6-28.5\%), \\  & & & trans-p-menth-2-en-1-ol (15.4–16.3\%) \\ \hline \multirow{2}{*}{NAEO} & [PERSON] et al. (2022) [35] & Ouagadougou (Burkina Faso) & Piperitone (59.8\%) and 2-carene (16.4\%) \\ \cline{2-3}  & [PERSON] (2004) [36] & Central (Kenya) &
\begin{tabular}{c} nepetalactone (14.67\%) and \\ \(\beta\)-cubebene (10.52\%) \\ \end{tabular} \\ \hline \hline \end{tabular}
\end{table} 
Table 7: Investigation on the chemical compositions of CSEO and NAEO. \begin{table}
\begin{tabular}{c c c} \hline \hline
**Essential Oil of Plant** & **Cancer Cell Lines Tested** & **Reference** \\ \hline _Cymbopogon nardus_ & Oral (KB) and blood (P388) & [PERSON] et al. (2006) [38] \\ \hline \multirow{6}{*}{_Cymbopogon flexuosus_} & Colon (HT-29, HCT-15, & \\  & SW-620, 502713), lung (A549, & \\  & HOP-62, H-226), cervix (SiHa), & \\  & oral (KB), prostate (DU-145) & [PERSON] et al. (2009) [39] \\  & and promylocytic leukemia & \\  & (HL-60) & \\ \hline _Cymbopogon citratus_ & Head and neck (HTB43) & [PERSON] et al. (2016) [40] \\ \hline \multirow{6}{*}{_Cymbopogon nardus_} & Breast (MCF-7), Cervic (HeLa) and myelogenous leukemia (K562). & [PERSON] et al. (2019) [41] \\ \cline{2-3}  & & Kidneys (VERO) and Cervic (SiHa) & [PERSON] et al. (2022) [42] \\ \hline \multirow{2}{*}{_Nepeta schirzaiana_} & Liver tissue (Hep-G2) and & \\  & breast (MCF-7). & [PERSON] et al. (2017) [43] \\ \hline \multirow{2}{*}{_Nepeta sibirica_} & Stomach (HL60, Kato III) & [PERSON] et al. (2012) [44] \\ \hline \multirow{6}{*}{_Nepeta tranjensis_} & Cervic (HeLa), myelogenous & \\  & leukemia (K562), Lung (A549), & \\ \cline{1-1}  & colon (LS-174) and breast & [PERSON] et al. (2017) [45] \\ \cline{1-1}  & (MDA-MB-231). & \\ \hline _Nepeta curviflora_ & Cervic (HeLa) & [PERSON] et al. (2020) [46] \\ \hline \multirow{2}{*}{_Nepeta curvidens_} & Lung (A549), oral (KB) and & \\ \cline{1-1}  & prostate (C450). & [PERSON] et al. (2020) [47] \\ \hline \hline \end{tabular}
\end{table} 
Table 8: Investigation of the anticancer activity of some essential oils of _Cymbopogon_ and _Nepeta_ species.