## 3 Perspectives and Outcomes of the Presented RHMS with a Focus on Diet-Related Approaches
### Schizophrenia, Dietary Habits, and Physical Health
#### 3.2.1 Link between Schizophrenia, Dietary Habits, and Physical Health
Additional findings show that a significant percentage of schizophrenia patients have fast eating habits [142], low fruit and fish consumption, and various nutrient deficiencies [143]. Out of all the metabolic abnormalities associated with schizophrenia, obesity, and dyslipidemia appear to have the greatest negative consequences on cognitive function. Diffuse brain alterations may be independently associated with obesity in the early phases of this disorder. In metabolic syndrome patients, there appears to be a correlation between poor eating practices and the degree of negative symptoms. One study found that individuals with schizophrenia had lower cognitive function when their negative and general symptoms were more severe [144]. Research also suggests that people who experience extreme negative symptoms have significant impairments in their working memory, indicating that the affected individuals have a larger chance of acquiring cognitive impairment over time if their diet quality remains unchanged and their negative symptoms do not improve. Schizophrenia significantly affects physical health as well, considering the compelling link between this psychosis and the heightened risk of various physical health issues. Among the prominent concerns is an increased susceptibility to cardiovascular risks, such as hypertension, atherosclerosis, and coronary heart disease, compared to the general population. Additionally, these individuals are at a greater risk of developing diabetes mellitus [145] and respiratory diseases [146]. The interplay between schizophrenia, dietary habits, and physical health is intricate and multifaceted. Lifestyle factors, including diet, contribute significantly to the overall well-being of individuals with schizophrenia. Poor dietary choices, such as high consumption of saturated fats and inadequate intake of essential nutrients, may not only exacerbate the symptoms of schizophrenia but also contribute to the development of physical health issues. The relationship between mental health and diet is bidirectional, as the symptoms of schizophrenia can influence an individual's dietary habits. Understanding this complex interplay is essential for developing comprehensive interventions that address both mental and physical aspects of health in individuals with schizophrenia. As the complex landscape of schizophrenia is more and more investigated, it becomes increasingly apparent that there is a critical relationship between this mental illness and eating patterns. The connection between these elements transcends mere coincidence, offering a compelling avenue for understanding the holistic health profile of individuals grappling with schizophrenia. Therefore, one of the nonpharmacological strategies that can be used to help individuals living with schizophrenia improve their overall health is dietary management. The urgency of comprehending the holistic impact of schizophrenia can be done through innovative approaches to management, particularly with the integration of RHMS, like the NeuroPredict Platform, which holds promise in revolutionising how to perceive, monitor, and intervene in the lives of individuals living with schizophrenia by bridging the gaps and providing real-time insights into the dynamic interplay between schizophrenia, dietary habits, and physical health. Despite significant progress in understanding the connections between schizophrenia--diet--and physical activities, there are currently notable gaps and areas of uncertainty. One critical gap lies in the limited exploration of the specific mechanisms through which dietary habits impact the onset and progression of schizophrenia. Understanding these mechanisms is essential for developing targeted interventions. Additionally, there is a need for more research on the long-term effects of dietary interventions on the mental and physical health outcomes of individuals with schizophrenia.