# Plant-Origin Additives from _Boswellia_ Species in Emulgel Formulation for Radiotherapy Skin Care
## Results  
### Physicochemical Properties of Obtained Formulations  
The physicochemical properties of the obtained topical formulations are given in Table 2.  
Under the analyzed storage conditions, the obtained samples were stable; no changes in their color, consistency, or odor were noted. There was also no phase separation. Samples E_P and Em_P, without active substances from the _Boswellia_ spp., were white in color, had a uniform, smooth, creamy or cream-gel consistency, respectiv  
\begin{table}
\begin{tabular}{c c c c c c c} \hline \hline
**Sample** & **Odor** & **Color** & **Consistency** & **Stability** & **pH** &
\begin{tabular}{c} **Mean Droplet Size of** \\ **Dispersed Phase** \(\mu\)**m \\ \end{tabular} \\ \hline E\_P & none & white & creamy & stable & 6.69 \(\pm\) 0.01 a & 19.0 \(\pm\) 1.5 \\ \hline Em\_P & none & white & cream–gel & stable & 5.88 \(\pm\) 0.03 b & 10.9 \(\pm\) 0.5 \\ \hline E\_SCO\({}_{2}\) & intense herbal scent & white & creamy & stable & 5.64 \(\pm\) 0.01 bc & 8.1 \(\pm\) 0.6 \\ \hline Em\_SCO\({}_{2}\) & intense herbal scent & white & creamy & stable & 6.12 \(\pm\) 0.01 ab & 15.1 \(\pm\) 0.9 \\ \hline E\_SO & intense herbal scent & white & creamy & stable & 4.92 \(\pm\) 0.06 cd & 6.6 \(\pm\) 0.7 \\ \hline Em\_SO & intense herbal scent & white & creamy & stable & 4.57 \(\pm\) 0.03 cd & 8.6 \(\pm\) 0.3 \\ \hline Em\_hSCO\({}_{2}\) & intense herbal scent & white & creamy & stable & 5.51 \(\pm\) 0.01 cd & 20.9 \(\pm\) 0.8 \\ \hline Em\_hSO & intense herbal scent & white & creamy & stable & 4.77 \(\pm\) 0.03 d & 7.0 \(\pm\) 0.6 \\ \hline \hline \end{tabular}
\end{table}
Table 2: Physicochemical properties of obtained topical formulations.  
After adding plant raw materials from the _Boswellia_ spp. to the product recipe, there were no changes in their color or consistency. There was a change in the odor, which became intense, and a herbal scent was noticed. The pH of the obtained formulations was 4.57 \(\pm\) 0.03-6.69 \(\pm\) 0.01. Preparations E_SO, EmhSO, and Em_SO, with the addition of _B. carterii_ essential oil, had a lower pH than Em_SCO\({}_{2}\) (with Soxhelt extract and CO\({}_{2}\) extract) and placebo formulations. Moreover, it has been shown that the method of the addition of the _Boswellia_ raw material (either to the emulsion or to the hydrogel) did not affect the pH of the formulation.  
Microscopic images of the preparations confirmed the structure of the oil in water macroemulgel (o/w macroemulgel) (Figure 2), where the continuous phase is a hydrogel matrix, and the dispersed phase is an oil-in-water emulsion (o/w emulsion). The structure of the emulgel was also preserved when the extract and/or oil were added to the hydrogel rather than to the emulsion. The obtained formulations were characterized by different droplet sizes of the dispersed phase: 6.6 \(\pm\) 0.7-20.9 \(\pm\) 0.8 \(\upmu\)m.  
Figure 2: Microscopic images of the obtained formulations: (**a**) E_P; (**b**) Em_P; (**c**) E_SCO\({}_{2}\); (**d**) Em_SCO\({}_{2}\); (**e**) E_SO; (**f**) Em_SO; (**g**) Em_hSCO\({}_{2}\); (**h**) Em_hSO.