## 3 Results
### Total As Concentrations in the Various Organss of the Experimental Animals  
Figure 2 represents the median total As concentrations expressed as mg/kg DW in livers (Figure 2a), kidneys (Figure 2b), spleens (Figure 2c), and lungs (Figure 2d) of the studied animals. The groups As and As + CBZ had significantly higher tissue total As concentrations compared to the control and the CBZ groups in all tissues analysed. Despite higher numerical total As concentrations in the As + CBZ group, no significant difference from the As group was detected. Likewise, the total As concentration in the control and CBZ were similar in all tissues analysed. Regarding the median total As concentrations in the liver (Figure 2a), statistically significant differences (\(p<0.05\)) were determined between the very high As treatment groups (the As group and the As + CBZ group) and the very low As treatment groups (the control group and the CBZ group). In the kidney (Figure 2b), the control and CBZ groups appeared to show comparable and low total As concentrations. In contrast, the groups exposed to very high As (the As group and the As + CBZ group) showed increased total As concentrations (\(p<0.05\)) in comparison to both the control and CBZ groups. Also, from the data, the As + CBZ group tended to accumulate the greatest amount of total As, but with no statistical difference (\(p>0.05\)) when compared to the As group. The total As concentrations in the spleens of the studied animals are shown in Figure 2c. The control and CBZ groups appeared to demonstrate comparable and low levels of total As concentrations. On the other hand, the As and As + CBZ groups had an enhanced total As amount (\(p<0.05\)) than the control and CBZ groups. Furthermore, the As + CBZ group appeared to have accumulated the highest quantity of total As than the As group, but the difference was not statistically significant (\(p>0.05\)). Figure 2d shows the total As concentrations in the lungs among the treatment animal groups after the termination of the experiment. The data show that the control and CBZ groups had low variations and similar and low concentrations of total As. However, the As and As + CBZ groups showed high variations and accumulated more (\(p<0.05\)) total As than the control and the CBZ groups. Even though the As + CBZ group seemed to have accumulated the most total As in the lungs, it was not statistically significant (\(p>0.05\)) compared to the As group. In summary, the sequence of total As concentrations across all studied organs was as follows: As + CBZ group \(>\) As group \(>>\) CBZ group \(\equiv\) control group. Furthermore,  
Figure 1: Body weights of experimental animals (medians \(\pm\) median absolute deviations) in grams (g); the columns marked by the same letter did not significantly differ at \(p<0.05\) within individual groups. when comparing the studied organs, kidney > liver > spleen > lungs was the order of total. As concentrations across the individual treatment animal groups. Individual As Species Concentrations and Methylation Capacities in the Liver of Experimental Animals  
Figure 3 shows inorganic As(III) (Figure 3a), inorganic As(V) (Figure 3b), dimethylarsinic acid (DMA; Figure 3c), and monomethylarsonic acid (MMA; Figure 3d) concentrations in the dried liver of the experimental animal groups, expressed in mg/kg. The As(III) concentrations in the control and CBZ groups tended to show low variations with similarly low concentrations, while the As and As + CBZ groups accumulated higher levels (\(p\) < 0.05) and were characterised by wider variations than the control and the CBZ groups. Figure 2: The median arsenic concentrations in mg/kg DW of (**a**) liver, (**b**) kidney, (**c**) spleen, (**d**) lungs of experimental animal groups; the columns marked by the same letter did not significantly differ at \(p\) < 0.05 within individual groups. From the data, the As + CBZ group seems to have accumulated the highest level of As(III) species.