###### Abstract
The resulting compounds were subjected to testing for both antibacterial and antioxidant activities. [PERSON] and [PERSON] reported that metal complexes derived from anthranilic acid derivatives represent a novel category of non-competitive inhibitors for \(\alpha\)-glucosidase [10]. Their in vitro analysis indicated a notably improved biological profile for the complexes when compared to both the free ligands and the metal ions themselves. Among these complexes, those containing Ag(I) exhibited the most remarkable inhibition of \(\alpha\)-glucosidase activity, showcasing a 4000-fold increase in potency compared to the free ligands. Recently, novel mixed-ligand dinuclear metal(II) complexes, consisting of nthranilic acid and pyridine-2-aldoxime, were obtained with Mn(II), Ni(II), Co(II), Cu(II), Zn(II), and Cd(II) [11]. All of these metal complexes were subject to assessment against various microbial strains. Notably, the Cd(II) complex exhibited promising inhibitory activity against _Staphylococcus aureus_, _Bacillus subtilis_, _Escherichia coli_, _Pseudomonas aeruginosa_, and _Candida albicans_. In a related study, six mixed-ligand complexes involving anthranilic acid, leucine, and monochloroacetic acid with copper, nickel, and cobalt were synthesized [12]. In their study, [PERSON] et al. presented the spectroscopic, structural, and antibacterial characteristics of mixed ligand complexes formed using a Schiff base along with anthranilic acid [13]. The research involved evaluating these compounds against two categories of bacteria: Gram-positive and Gram-negative strains. [PERSON] investigated a study where several mixed-ligand complexes incorporating Co(II), Ni(II), Cu(II), and Zn(II), along with anthranilic acid and 2-(1H-benzimidazol-2-yl)aniline derivatives, were synthesized and characterized [14]. The results indicated that the complexes exhibit an octahedral geometry with the presence of two water molecules. In the PhD thesis of [PERSON] in 2011, mixed-ligand complexes with Cu(II), Ni(II), Zn(II), Mn(II) from sulfonamides of antranilic acid and 2,3,4-aminopyridines [15] were reported. Anthranilic acid readily undergoes reactions with W(VI) oxo or organoimido tetrachlorides, resulting in the formation of complexes with the following structure: [W(X)Cl3(HO\({}_{2}\)C C\({}_{6}\)H\({}_{4}\)NH-2)] [X = O (1), NPh (2)] [16]. The chelating ligand derived from anthranilic acid coordinates in an acid/amide form. Comparative structural analysis has been conducted, drawing parallels between related complexes involving salicylic acid. [PERSON] et al. presented a study involving the immobilization of the rhodium/anthranilic acid complex onto fishbone carbon nanofibers [17]. [PERSON] et al. reported the synthesis and analgesic activity of hydrazides derived from 2-phenoxybenzoic acid and N-phenyl anthranilic acid [18]. Additionally, they explored the oxidative polymerization of N-phenyl anthranilic acid within a heterophase system. [PERSON] et al. focused on the synthesis of anthranilic acid derivatives [19]. They achieved this through an iron-catalyzed ortho amination process involving aromatic carboxamides and N-chloroamines. Recently, [PERSON] and [PERSON] presented a mini-review exploring the medicinal chemistry of anthranilic acid derivatives [20]. In conclusion, we have summarized that the anthranilic acid and their derivatives and various metal complexes have interesting antimicrobial activities [6; 7; 8; 9; 10; 11; 12; 13], cytotoxic [4], anti-inflammatory properties [2; 3] and are the inhibitors of aldo-keto reductase enzymes [21]. **Author Contributions:** Conceptualization, P.M. and M.H. ; writing--original draft preparation P.M. and M.H. ; writing--review and editing P.M. All authors have read and agreed to the published version of the manuscript. **Funding:** We acknowledge the financial support from the Fund for Scientific Research of the Plovdiv University, project CTI 23-XPh-006. **Conflicts of Interest:** The authors declare no conflict of interest.