## 3 Results  
In the control, none of the 8 implants was ulcerated; 2 of the subjects had developed clinical Baker grade III/IV capsular contracture (Figure 1). Figure 1: Silicon implant non treated–moment of extraction of the implant with the view of the remaining thick capsule. The rifampicin group had 1 ulcerated implant, and 2 implants had developed Baker grade II/III capsular contracture (Figure 2). In the dexamethasone group, 2 of the 12 implants were ulcerated, and no cases of capsular contracture were observed (Figure 3). The autologous centrifuged fat group had no ulcerated implants and no clinical capsular contracture has been found. The capsules with contracture were adherent to the adjacent tissue, dense and stiff (Figure 4). Histology assessment: in the control group was observed an active chronic inflammation associated with giant foreign body cell reaction. More specifically lymphocytes and plasma (Ly-PL) cells were associated with neutrophil _Polymorphonuclear_ leukocytes (PMN) in 10% and giant foreign cell reaction in the proportion of 30% (Figures 5 and 6). Figure 4: Silicon implant treated with autologous centrifugated fat (**a**) moment of insertion and fat harvesting; (**b**) fat injection in the implant pocket; (**c**) moment of extraction of the implant with no capsular contracture. Figure 3: Silicon implant treated with dexamethasone–moment of extraction of the implant with no capsular contracture. Figure 2: Silicon implant treated with rifampicin–moment of extraction of the implant and a remaining capsule thinner. In the rifampicin group, microtextured breast implant induced an inflammatory chronic reaction with low inflammatory infiltrate consisting mostly of Ly-PL cells (90%), associated with a giant foreign body cell reaction in the proportion of 10% and chronic inflammation with moderate inflammatory infiltrates consisting mostly of lymphocytes and plasma cells (80%), associated with a giant foreign cell reaction in the proportion of 20%. In dexamethasone group has been identified acute inflammation with abundant inflammatory infiltrate with PMN (70%), the giant cellular reaction of foreign body in the proportion of (15%), macrophages (10%) and Ly-PL cells about (5%) and chronic active inflammation with abundant inflammatory infiltrate in which Ly-PL cells (30%) were associated with neutrophal PMN in (10%), macrophages (2%) and giant foreign body reaction in the proportion of (58%). Fat cell group had chronic inflammation to the implants with low inflammatory infiltrate consisting mostly of Ly-PL cells (95%), associated with a giant foreign body reaction in a proportion of 5% and in one case chronic active inflammation with reduced Ly-PL inflammatory infiltrate (90%), associated with PMN (10%) (Figures 7 and 8) (Table 1). Figure 5: High level of inflammatory infiltrate at six weeks after surgery. Figure 6: Giant foreign cell reaction at six weeks after surgery. Figure 7: Low inflammatory infiltrate at six weeks after surgery. Statistical analyses revealed low levels of acute and chronic inflammation in the group study treated with autologous centrifugated fat compared to the other three groups. The rifampicin group had a higher rate of acute and chronic inflammation. In the control group, acute inflammation was encountered in half of the study subjects and the rate of chronic inflammation was slightly increased. Dexamethasone intramuscular administration reduced the chronic inflammatory process (Figure 9). Correlations between types of inflammatory cells in the contracture capsule of the silicone implants in the studied groups showed a significant statistical association of macrophage, mastocytes and gigantocellular reaction and the type of treatment applied in each group (Table 2). Also chronic inflammation was statistical significant associated in our