## 5 Conclusions
and A.A. ([PERSON]); Investigation, V.F., K.M., K.N., K.K, V.M., V.P., P.A., K.T., A.A. ([PERSON]) and A.A. ([PERSON]); Methodology, V.F., K.M. and A.A. ([PERSON]); Project administration, P.D.B. and A.A. ([PERSON]); Resources, A.A. ([PERSON]), P.D.B. and A.A. ([PERSON]); Software, V.F., K.M., P.A. and K.T. ; Supervision, P.D.B., A.A. ([PERSON]) and A.A. ([PERSON]); Validation, V.F., K.M. and A.A. ([PERSON]); Visualization, V.F. and K.M. ; Writing--original draft, V.F., K.M., K.N., V.P. and A.A. ([PERSON]); Writing--review and editing, V.F., K.M., K.N., V.M., V.P., P.A., K.T., M.G.T., A.A. ([PERSON]), P.D.B. and A.A. ([PERSON]). All authors have read and agreed to the published version of the manuscript. This research project was supported by the Hellenic Foundation for Research and Innovation (H.F.R.I) [[https://www.elidek.gr](https://www.elidek.gr)]([https://www.elidek.gr](https://www.elidek.gr)) (accessed on 30 April 2024) under the \"2 nd Call for H.F.R.I. Research Projects to support Faculty Members & Researchers\" (Project Number: 4391). The study was conducted in accordance with the Declaration of Helsinki. The NeuroSuitUp protocol was approved by the Committee for Bioethics and Ethics of the School of Medicine, Aristotle University of Thessaloniki with the protocol number 188117/2022 in the Committee sitting 68/13-7-2022 following the application with the protocol number 165080/2022. The HEROES protocol was approved by the Committee for Bioethics and Ethics of the School of Medicine, Aristotle University of Thessaloniki with the protocol number 266604/2022 in the Committee sitting 73/12-10-2022 following the application with the protocol number 243371/2022. Informed Consent Statement:Informed consent was obtained from all subjects involved in the study. Data Availability Statement:Data from the NeuroSuitUp and HEROES studies will be made publicly available after the completion of the projects and will be accessible through their respective institutional project web pages under an Attribution-NonCommercial-NoDerivatives 4.0 International license. Data of the analysis presented in the current manuscript and the related code can be made available via a request to the authors following a Memorandum of Understanding (MoU) in the context of Open Research Initiative. We would like to thank the following members of the Biomedical Electronics Robotics and Devices (BERD) research group of the Medical Physics and Digital Innovation Laboratory, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki ([PERSON], [PERSON], [PERSON], [PERSON], [PERSON] and [PERSON]) who are collaborators in the NeuroSuitUp and HEROES projects but were not listed as authors in this manuscript. The authors declare no conflicts of interest. The funding body had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results. The following abbreviations are used in this manuscript:  
ADLsActivities of Daily Living  
AESApathy Evaluation Scale  
BAIBeck Anxiety Index  
BDIBeck's Depression Inventory  
ComSSCommunication Software Subsystem