## 3 Results
### Genetic Risk Score for Obesity and Eating Behavior  
Based on the sample participant's anthropometric and genotypic description, the resulting genetic risk score (GRS) categories were Q1: \(\leq\)19 points; Q2: 20-22 points; Q3: 23-25 points; and Q4: \(>\)25 points. Table 3 presents the mean scores of the eight subscales of the CEBQ, stratifying the results according to GRS quartile categories. The trend is increasing for the pro-eating scales and decreasing for the anti-eating scales. The pro-eating subscales of food responsiveness (FR) and emotional overeating (EOE), as well as the anti-eating subscale of emotional undereating (EUE), were the eating behavioral traits significantly associated with GRS. As genetic predisposition to obesity increases, items related to food cravings and emotional hunger score higher. The multinomial logistic regression model highlighted associations between all pro-intake subscales and selected SNPs, analyzed independently (Figure 1). \begin{table}
\begin{tabular}{c c c c c c c} \hline  & \multicolumn{3}{c}{**6–10 Years**} & \multicolumn{3}{c}{**11–16 Years**} \\  & \multicolumn{3}{c}{**(Mean \(\pm\) SD)**} & \multicolumn{3}{c}{**(Mean \(\pm\) SD)**} \\ \cline{2-7}  & **Male** & **Female** & **\(p\)** & **Male** & **Female** & **\(p\)** \\ \hline Weight (kg) & 33.54 \(\pm\) 10.50 & 34.46 \(\pm\) 8.18 & 0.440 & 51.28 \(\pm\) 13.30 & 50.53 \(\pm\) 12.52 & 0.939 \\ \hline Height (cm) & 134.42 \(\pm\) 10.15 & 136.23 \(\pm\) 9.42 & 0.161 & 155.48 \(\pm\) 11.46 & 155.92 \(\pm\) 8.30 & 0.179 \\ \hline Waist circumference (cm) & 65.10 \(\pm\) 10.54 & 63.91 \(\pm\) 8.12 & 0.323 & 75.45 \(\pm\) 11.31 & 70.61 \(\pm\) 8.70 & \(<\)0.001 * \\ \hline Tricipital skinfold (mm) & 12.64 \(\pm\) 6.17 & 13.82 \(\pm\) 4.94 & 0.100 & 14.70 \(\pm\) 9.60 & 15.76 \(\pm\) 6.12 & 0.179 \\ \hline Bicipital skinfold (mm) & 8.06 \(\pm\) 4.83 & 8.76 \(\pm\) 3.75 & 0.202 & 9.66 \(\pm\) 5.34 & 9.61 \(\pm\) 4.25 & 0.838 \\ \hline Subescapular skinfold (mm) & 9.14 \(\pm\) 6.37 & 10.00 \(\pm\) 4.87 & 0.235 & 12.01 \(\pm\) 7.50 & 12.52 \(\pm\) 6.50 & 0.548 \\ \hline Suprailiac skinfold (mm) & 10.57 \(\pm\) 7.84 & 11.24 \(\pm\) 6.57 & 0.477 & 15.16 \(\pm\) 8.77 & 14.30 \(\pm\) 6.92 & 0.372 \\ \hline \hline \end{tabular}
*Significant differences between groups.  
\end{table} 
Table 1: Direct anthropometric measurements of the sample as a function of sexual dimorphism by age group. The SNPs rs1801725 (CASR) and rs1137101 (LEPR) were independently associated with enjoyment of food (EF), showing, in the first case, an increase in the score of this scale with an OR of 1.846 (95% CI: 1.023-3.329; \(p=0.024\)). In the second case, the same scale (EF) was reduced, with an OR of 0.586 (95% CI: 0.329-0.980; \(p=0.024\)). Food responsiveness (FR) was increased by 1.827-fold (95% IC: 1.090-3.062; \(p=0.041\)) for each risk allele in SNP rs10887741 (PAPSS2) and by 2.224-fold in SNP rs1421085 (95% IC: 1.117-4.427 \(p=0.042\)). In contrast, for each risk allele in SNP rs693839 (SPRY2), FR was reduced, with an OR of 0.519 (95% IC: 0.309-0.872; \(p=0.019\)). Emotional overeating (EOE) subscale scores were increased by 1.628-fold for each risk allele of SNP rs10887741 (PAPSS2) (95% IC: 1.016-2.698; \(p=0.049\)). Finally, the desire to drink (DD) subscale score was reduced for each risk allele of SNP rs3761445 (PLA2G6), with an OR of 0.501 (95% IC: 0.291-0.864; \(p=0.021\)).