_applied sciences_  
_Editorial_  
New Trends in Biosciences  
[PERSON] 1,2,*(), [PERSON] 3(), [PERSON] 4() and [PERSON] 3()  
Footnote 1: [[https://www.mdpi.com/journal/applsci](https://www.mdpi.com/journal/applsci)]([https://www.mdpi.com/journal/applsci](https://www.mdpi.com/journal/applsci))  
the growth performance, intestinal barrier function, fecal short-chain fatty acids (SCFAs) concentration, and fecal _Lactobacillus_ and _Bifidobacterium_ of piglets [11]. In dentistry, silver nanoparticles (AgNPs) have progressively earned great interest as antimicrobial drugs and are widely used in several biomedical fields. Recent progress in the analysis of complex bacterial communities has demonstrated the richness of the oral microbiota and the presence of numerous previously unexplained strains. Several studies have been dedicated to the investigation of antimicrobial peptides (AMPs) [12]. Enamel defects (EDs) are qualitative and/or quantitative disturbances of the dental surface. To date, the responsiveness to remineralizing treatments has been studied ex vivo, on dental sections from extracted teeth. In a proof-of-concept study, [PERSON] et al. [13] aims to establish if in vivo reflectance confocal laser scanning microscopy is able to visualize the changes in the enamel architecture on living teeth before, during, and after remineralizing treatments by casein phosphopeptide-amorphous calcium phosphate (CPP-ACP). Other authors try to quantify the relative bioavailability of microencapsulated vitamins A and E in nursery pigs and compare the effects of vitamin forms and vitamin levels on the plasma vitamin content and growth performance of weaned piglets. Results show that microencapsulation can improve the bioavailability of vitamins, and supplementation with high levels of vitamins was able to improve the growth performance of the piglets [14]. In an interesting review, the authors introduce publicly available databases for drug repositioning and summarize the approaches taken for drug repositioning. They also highlight and compare their characteristics and challenges, which should be addressed for the future realization of drug repositioning [15]. [PERSON] et al. review the mechanisms underlying inflammation-related Temporomandibular disorders (TMD), highlighting the potential role of polyphenols as a promising approach to develop innovative management of temporomandibular diseases [16]. Another group aimed to find whether it is possible that beta-catenin, associated with the development of serious systemic diseases, as well as the neoplastic process, plays a role in the development of pseudoexfoliation syndrome (PEX). It might be possible for PEX, due to it being easily recognizable, to be the first indicator of serious kidney or cardiac diseases, as well as cancer metastases [17]. Because glycogen storage disease (GSD) represents a group of twenty-three types of metabolic disorders which damage the capacity of the body to store glucose classified based on the enzyme deficiency involved and affected patients could present some oro-facial alterations, [PERSON] et al. conducted a systematic review of the literature among different search engines using PICOS criteria, to catalog and characterize oral manifestations in these patients [18]. In an additional original study, the authors propose a technique that can be used by individuals with lower limb amputations for the management of their residual limb's volume variations, especially when using prosthetic socks. The focus of this study was to develop a low-complexity system such that it would be inexpensive, easy to install inside the user's prosthetic socket, less prone to failures, and easy to use from the end-user's perspective. These characteristics would increase the impact that this technology would have on the affected population by enhancing the adaptability of the developed system [19]. Double filtration plasmapheresis (DFPP) is an emerging semi-selective apheretic method for treating immuno-mediated neurological diseases. In this Special Issue, [PERSON] et al.