## 3 Materials and Methods
### Fermentation, Extraction, and Isolation  
The fungus was cultivated in a potato dextrose agar (PDA) plate under 25 \({}^{\circ}\)C for four days, and then the fresh mycelia and spores were inoculated into 500 mL Erlenmeyer flasks (\(\times\)2), each containing 100 mL potato dextrose broth (PDB) medium and followed by cultivation in a rotary shaker under 25 \({}^{\circ}\)C at 200 rpm for four days. The seed cultures were subsequently inoculated to 30 Erlenmeyer flasks (1 L) (each containing 80 g rice and 120 mL sea water) after autoclaving at 121 \({}^{\circ}\)C for 22 min. The fermentation was performed under static conditions at 25 \({}^{\circ}\)C for 26 days. The fermented material was fragmented using a stick and extracted successively with EtOAc three times, and then evaporated under reduced pressure to get an EtOAc extract (16.2 g). The extract was subjected to the vacuum liquid chromatography column on silica gel eluting with a gradient of CH\({}_{2}\)Cl\({}_{2}\) and MeOH (1:0 to 0:1) to furnish fractions A and B. The fraction B (8.5 g) was subsequently separated by CC on ODS with MeOH/H\({}_{2}\)O elution (30-100%) to obtain fourteen fractions (Fr.1-Fr.14). Fraction Fr.3 (147 mg) was separated by CC on silica gel eluting with petroleum ether (PE)/EtOAc (10:1) to obtain two subfractions. The former was further purified by semi-preparative HPLC with the mobile phase of MeOH/H\({}_{2}\)O (3:7) to yield **2** (1.8 mg) and **5** (21.0 mg), whereas the latter was separated by semi-preparative HPLC (CH\({}_{3}\)CN/H\({}_{2}\)O, 1:9) to get **1** (0.5 mg). Fraction Fr.5 (333 mg) was chromatographed by CC on silica gel eluting with CH\({}_{2}\)Cl\({}_{2}\)/MeOH (30:1) to furnish two subfractions, whereas the former was further separately purified by semi-preparative HPLC using CH\({}_{3}\)CN/H\({}_{2}\)O (19:81) elution to obtain **10** (4.0 mg), and the latter using MeOH/H\({}_{2}\)O (7:18) elution to yield **4** (3.0 mg). Fraction Fr.7 (489 mg) was subjected to silica gel CC with CH\({}_{2}\)Cl\({}_{2}\) and MeOH gradient elution (1:0\(\rightarrow\)0:1) to yield two subfractions (Fr.7-1 and Fr.7-2). Subtraction Fr.7-1 was separated by semi-preparative HPLC purification (CH\({}_{3}\)CN/H\({}_{2}\)O, 23:77) to get **1** (1.4 mg) and **3** (3.8 mg). Subtraction Fr.7-2 was purified by semi-preparative HPLC (CH\({}_{3}\)CN/H\({}_{2}\)O, 37:63) to yield **9** (1.2 mg). Fraction Fr.11 (146 mg) was separated by silica gel CC eluting with CH\({}_{2}\)Cl\({}_{2}\)/acetone gradient from 1:0 to 0:1 to furnish two subfractions, whereas the former was further separated using CC on a Sephadex LH-20 (MeOH) and semi-preparative HPLC (CH\({}_{3}\)CN/H\({}_{2}\)O, 3:7) to obtain **7** (18.5 mg) and **8** (3.0 mg), respectively. Fraction Fr.13 (545 mg) was subjected to CC on silica gel eluting with PE/EtOAc (1:0\(\rightarrow\)0:1) to get four subfractions (Fr.13-1-Fr.13-4). Subtraction Fr.13-1 was subjected to semi-preparative HPLC with the mobile phase of CH\({}_{3}\)CN/H\({}_{2}\)O (39:61) to yield **6** (1.0 mg). Aspermonoterpenoid A (**1**): colorless oil; \(\left[\alpha\right]_{\rm D}^{25}\)+54 (\(c\) 0.06, MeOH); UV (MeOH) \(\lambda_{\rm max}\) (log \(\varepsilon\)) 223 (1.59) nm; \({}^{1}\)H and \({}^{13}\)C NMR data, see Table 1; HRESIMS \(m/z\) 221.0784 [M + Na]\({}^{+}\) (calcd. for C\({}_{10}\)H\({}_{14}\)O\({}_{4}\)Na, 221.0790). Aspermonoterpenoid B (**2**): colorless oil; \(\left[\alpha\right]_{\rm D}^{25}\) -38 (\(c\) 0.07, MeOH); UV (MeOH) \(\lambda_{\rm max}\) (log \(\varepsilon\)) 229 (0.96) nm; ECD (MeOH) \(\lambda_{\rm max}\) (\(\Delta\varepsilon\)) 199 (-21.88), 222 (-5.77), 231 (-13.46), 260 (-0.15) nm; \({}^{1}\)H and \({}^{13}\)C NMR data, see Table 1; HRESIMS \(m/z\) 205.0845 [M + Na]\({}^{+}\) (calcd. for C\({}_{10}\)H\({}_{14}\)O\({}_{3}\)Na, 205.0841). Asperphenylpyrone (**3**): colorless oil; UV (MeOH) \(\lambda_{\text{max}}\) (log \(\varepsilon\)) 204 (1.67), 248 (0.85), 315 (0.28) nm; \({}^{1}\)H and \({}^{13}\)C NMR data, see Table 2; HRESIMs _m_/z 333.0741 [M + Na]\({}^{+}\) (caled.