## Results
### Biochemical Analysis
\begin{table}
\begin{tabular}{l l l l l l l l l l l l l l l l} \hline \hline \multicolumn{1}{c}{**VIG**} & \multicolumn{1}{c}{**TCT-04**} & \multicolumn{1}{c}{**FGB**} & \multicolumn{1}{c}{**FPC-06**} & \multicolumn{1}{c}{**TDS-06**} & \multicolumn{1}{c}{**TDS-06**} & \multicolumn{1}{c}{**H-18**} & \multicolumn{1}{c}{**H-18**} & \multicolumn{1}{c}{**H-18**} & \multicolumn{1}{c}{**H-18**} & \multicolumn{1}{c}{**H-18**} & \multicolumn{1}{c}{**H-18**} & \multicolumn{1}{c}{**H-18**} & \multicolumn{1}{c}{**H-18**} & \multicolumn{1}{c}{**H-18**} & \multicolumn{1}{c}{**H-18**} & \multicolumn{1}{c}{**H-18**} & \multicolumn{1}{c}{**H-18**} \\ \hline \multicolumn{14}{l}{**VIG**} \\ \hline \mul  
\begin{table}
\begin{tabular}{c c c c c c c c c c c c c c c} \hline  & \multicolumn{2}{c}{**VIGF**} & \multicolumn{2}{c}{**TGG-M1**} & \multicolumn{2}{c}{**TGB**} & \multicolumn{2}{c}{**TGG-M0**} & \multicolumn{2}{c}{**TNS-M0**} & \multicolumn{2}{c}{**L-M0**} & \multicolumn{2}{c}{**R-M1**} & \multicolumn{2}{c}{**R-M2**} & \multicolumn{2}{c}{**R-M2**} & \multicolumn{2}{c}{**R-M3**} & \multicolumn{2}{c}{**R-M4**} & \multicolumn{2}{c}{**R-M5**} & \multicolumn{2}{c}{**R-M5**} & \multicolumn{2}{c}{**R-M5**} & \multicolumn{2}{c}{**R-M5**} & \multicolumn{2}{c}{**R-M5**} & \multicolumn{2}{c}{**R-M5**} & \multicolumn{2}{c}{**R-M5**} \\ \hline SPD(1)-M0 & Configuration & - & - & - & - & - & - & - & - & - & - & - & - & - & - & - \\  
\begin{table}
\begin{tabular}{l l l l l l l l l l l l l l}  & \multicolumn{1}{c}{**VIGG**} & \multicolumn{1}{c}{**TEG-M1**} & \multicolumn{1}{c}{**FGG**} & \multicolumn{1}{c}{**FGG-M6**} & \multicolumn{1}{c}{**TDS-M6**} & \multicolumn{1}{  
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\begin{table}
\begin{tabular}{l l l l l l l l l l l l l l l} \hline \hline
**Outcome** & \multicolumn{1}{c}{**VEGF**} & \multicolumn{1}{c}{**TGF-91**} & \multicolumn{1}{c}{**FGFb**} & \multicolumn{1}{c}{**PDGF-bb**} & \multicolumn{1}{c}{**TNF-\(\alpha\)**} & \multicolumn{1}{c}{**II–10**} & \multicolumn{1}{c}{**IL–6**} & \multicolumn{1}{c}{**IL–4**} & \multicolumn{1}{c}{**IL–1B**} & \multicolumn{1}{c}{**IL–8**} & \multicolumn{1}{c}{**IL–IRA**} & \multicolumn{1}{c}{**IFN-\(\gamma\)**} \\ \hline Clot & \multicolumn{1}{c}{VAS} & \multicolumn{1}{c}{Spearman \(\rho\)} & \multicolumn{1}{c}{\(-\)0.013} & \multicolumn{1}{c}{0.317} & \multicolumn{1}{c}{0.299} & \multicolumn{1}{c}{0.317} & \multicolumn{1}{c}{\(-\)0.316} & \multicolumn{1}{c}{0.068} & \multicolumn{1}{c}{\(-\)0.273} & \multicolumn{1}{c}{\(-\)0.209} & \multicolumn{1}{c}{\(-\)0.050} & \multicolumn{1}{c}{\(-\)0.387} & \multicolumn{1}{c}{0.046} & \multicolumn{1}{c}{\(-\)0.300} \\ (day 1) & \(p\) value & \multicolumn{1}{c}{0.957} & \multicolumn{1}{c}{0.173} & \multicolumn{1}{c}{0.200} & \multicolumn{1}{c}{0.173} & \multicolumn{1}{c}{0.175} & \multicolumn{1}{c}{0.776} & \multicolumn{1}{c}{0.244} & \multicolumn{1}{c}{0.378} & \multicolumn{1}{c}{0.386} & \multicolumn{1}{c}{0.092} & \multicolumn{1}{c}{0.847} & \multicolumn{1}{c}{0.199} \\ \hline VAS & Spearman \(\rho\) & 0.074 & 0.042 & 0.107 & 0.042 & -0.274 & -0.107 & -0.191 & -0.152 & -0.044 & -0.055 & -0.133 & -0.299 \\ (day 2) & \(p\) value & 0.788 & 0.859 & 0.855 & 0.859 & 0.243 & 0.653 & 0.421 & 0.521 & 0.853 & 0.819 & 0.576 & 0.200 \\ \hline VAS & Spearman \(\rho\) & \(-\)0.020 & \(-\)0.127 & \(-\)0.077 & \(-\)0.127 & \(-\)0.268 & -0.069 & -0.037 & -0.002 & 0.191 & -0.008 & 0.008 & -0.292 \\ (day 3) & \(p\) value & 0.933 & 0.994 & 0.748 & 0.594 & 0.254 & 0.773 & 0.876 & 0.944 & 0.420 & 0.975 & 0.972 & 0.211 \\ \hline CI & Spearman \(\rho\) & \(-\)0.182 & \(-\)0.045 & \(-\)0.010 & \(-\)0.045 & 0.234 & 0.222 & \(-\)0.036 & -0.027 & -0.197 & -0.146 & 0.098 & 0.234 \\ (day 7) & \(p\) value & 0.443 & 0.850 & 0.967 & 0.850 & 0.321 & 0.346 & 0.882 & 0.910 & 0.405 & 0.540 & 0.662 & 0.321 \\ \hline CI & Spearman \(\rho\) & \(-\)0.349 & 0.091 & 0.172 & 0.091 & 0.404 & 0.326 & 0.163 & 0.057 & 0.089 & -0.076 & 0.442 & 0.366 \\ (day 14) & \(p\) value & 0.132 & 0.703 & 0.469 & 0.703 & 0.077 & 0.161 & 0.492 & 0.810 & 0.710 & 0.752 & 0.051 & 0.113 \\ \hline SPID\({}_{24-18}\) & Spearman \(\rho\) & \(-\)0.136 & 0.116 & 0.105 & 0.116 & -0.002 & 0.146 & -0.031 & -0.000 & 0.011 & -0.194 & 0.090 & -0.017 \\  & \(p\) value & 0.567 & 0.618 & 0.599 & 0.216 & 0.992 & 0.533 & 0.895 & 0.814 & 0.950 & 0.412 & 0.707 & 0.042 \\ SPID\({}_{24-27}\) & Spearman \(\rho\) & \(-\)0.686 & 0.345 & 0.216 & 0.214 & 0.781 & 0.547 & 0.538 & 0.544 & 0.515 & 0.268 & 0.888 & -0.691 \\  & \(p\) value & 0.659 & 0.356 & 0.360 & 0.256 & 0.706 & 0.247 & 0.536 & 0.519 & 0.518 & 0.528 & 0.299 & 0.134 & 0.691 \\  & \(p\) value & 0.502 & 0.258 & 0.168 & 0.238 & 0.797 & 0.405 & 0.495 & 0.421 & 0.784 & 0.200 & 0.613 & 0.720 \\ \hline L-PRF & \multicolumn{1}{c}{VAS} & \multicolumn{1}{c}{Spearman \(\rho\)} & \multicolumn{1}{c}{\(-\)0.228} & \multicolumn{1}{c}{\(-\)0.122} & \multicolumn{1}{c}{0.147} & \multicolumn{1}{c}{\(-\)0.403} & \multicolumn{1}{c}{\(-\)0.199} & \multicolumn{1}{c}{0.278} & \multicolumn{1}{c}{\(-\)0.300} & \multicolumn{1}{c}{\(-\)0.250} & \multicolumn{1}{c}{\(-\)0.138} & \multicolumn{1}{c}{\(-\)0.379} & \multicolumn{1}{c}{0.031} & \multicolumn{1}{c}{\(-\)0.240} \\ (day 1) & \(p\) value & 0.333 & 0.609 & 0.556 & 0.078 & 0.400 & 0.235 & 0.198 & 0.288 & 0.560 & 0.100 & 0.896 & 0.309 \\ \hline VAS & Spearman \(\rho\) & \(-\)0.050 & \(-\)0.243 & \(-\)0.302 & \(-\)0.524 & \(-\)0.154 & 0.207 & -0.165 & -0.138 & 0.093 & -0.223 & 0.072 & -0.301 \\ (day 2) & \(p\) value & 0.803 & 0.301 & 0.195 & **0.018** & 0.516 & 0.381 & 0.488 & 0.563 & 0.697 & 0.344 & 0.763 & 0.198 \\ \hline VAS & Spearman \(\rho\) & 0.120 & \(-\)0.208 & \(-\)**0.479*** & \(-\)0.709*** & \(-\)0.091 & \(-\)0.003 & -0.249 & -0.216 & -0.135 & -0.125 & 0.013 & -0.172 \\ (day 3) & \(p\) value & 0.615 & 0.378 & **0.033** & **0.009** & 0.704 & 0.989 & 0.289 & 0.360 & 0.570 & 0.363 & 0.957 & 0.468 \\ \hline CI & Spearman \(\rho\) & \(-\)0.171 & 0.202 & \(-\)0.325 & **0.15*** & \(-\)0.040 & \(-\)0.105 & 0.106 & 0.042 & \(-\)0.007 & 0.052 &