# Smart Healthcare Applications over 5G Networks: A Systematic Review
## 2 Method  
To develop this systematic literature review about 5G technology applications in smart healthcare, information discrimination was carried out following a systematic process. Through the PRISMA method [16], the research questions (RQ) that guide our study are raised. * RQ1: What are the healthcare applications that can be developed with the 5G implementation in smart health systems? Through this question, we intended to know the different health systems developed with the use of 5G technology, its benefits, and marked trends in terms of the deployment of new supports. * RQ2: What is the type of technology used, and what technical requirements does an intelligent health system demand through the use of 5G? This question was aimed at identifying the devices, tools, and technical characteristics that enable the development and operation of smart healthcare systems. It also aims to detect the technical characteristics that developers consider essential in the generation of applications. RQ3: What are the security mechanisms or protocols required by smart health systems based on 5G? This question was aimed at finding out what security measures are used in smart health systems based on 5G, related to security architectures and encryption protocols in the information transmission. After raising the research questions, the keywords that allow us to structure the research string (RS) were established: \"Mobile network 5G\", \"smart healthcare\", \"IoMT\", \"telemedicine\", and \"eHealth\". The research string (RS) was defined as follows:  
_RS_ = (Mobile network 5G OR 5G) AND (smart healthcare OR telemedicine OR eHealth OR IoMT) AND (applications OR apps OR devices)  
Once the RS was structured, the document search stage began. The databases that were consulted were: IEEE, Science Direct, Scopus, Web of Science, Springer, Wiley Online Library, Gale Power Search, and Association of Computing Machinery (ACM). These databases were selected based on the multidisciplinary nature of their publications and previous work. An attempt has been made to include all those databases used by other authors in previous work. As the number of articles obtained was adequate, no additional technique was applied to expand the results. In order to filter the scientific articles, the systematic process established in the PRISMA method was applied. As shown in Figure 1. We followed three stages, each with inclusion and exclusion criteria. Before starting with the identification stage, a filter was applied in the databases, considering that 5G technology appeared approximately in 2013 [17]. * In stage 1 (identification), the metadata were extracted from the retrieved articles, and the inclusion and exclusion criteria were used, starting with the publication year. As shown in Figure 2, since 2016 there has been an increase in the number of publications produced. With this background, we decided to review the documents published  
Figure 1: Stages of the PRISMA method. from 2016 to 2021. Within this framework, we also eliminated systematic reviews and state-of-the-art studies that were not based on a technological foundation and showed previous analyses that were inappropriate to the objective of this research. * In stage 2 (screening), we reviewed the articles according to title, abstract, and keywords. Articles unrelated to our topic and brief, non-relevant articles were removed. Articles that could not be accessed were also discarded. * In stage 3 (eligibility), we reviewed each article in depth, including for review those that clearly expressed and detailed their applications. Table 1 shows a summary of the basic characteristics of the studies finally included. These are: authors, source, publication year, and country in which each study was conducted. Regarding the type of document, 65.91% (\(n=29\)) are journal articles, 20.45% (\(n=9\)) are conference papers, and finally, 13.64% (\(n=6\)) are chapters and sections of books.