## 2 Results
### Identified Staphylococcus Comenes Impacting HMEC-1 Damages
\begin{table}
\begin{tabular}{c c c c} \hline \hline
**Locus** & **Gene Name** & **Description** & **\% EC Damage** \\   SAUSA300\_0244 & hypothetical & zinc-binding dehydrogenase family oxidoreductaseuse & 12.05 \(\pm\) 9.79 \\ SAUSA300\_2022 & _rpeF_ & RNA polymerase sigma factor SigB & 12.05 \(\pm\) 6.83 \\ SAUSA300\_1089 & _lspA_ & lipoprotein signal peptidase & 11.97 \(\pm\) 6.81 \\ SAUSA300\_1618 & _hemX_ & hemA concentration negative effector hemX & 11.88 \(\pm\) 1.05 \\ SAUSA300\_0117 & _sirA_ & iron compound ABC transporter iron compound-binding protein SirA & 11.83 \(\pm\) 7.84 \\ SAUSA300\_0899 & _mcA_ & adaptor protein & 11.58 \(\pm\) 10.37 \\ SAUSA300\_2492 & hypothetical & acetyltransferase family protein & 11.55 \(\pm\) 7.80 \\ SAUSA300\_1433 & hypothetical & putative phage regulatory protein & 11.41 \(\pm\) 8.17 \\ SAUSA300\_1244 & _mscl._ & large conductance mechanosensitive channel protein & 11.32 \(\pm\) 7.21 \\ SAUSA300\_0049 & hypothetical & hypothetical protein & 11.30 \(\pm\) 0.62 \\ SAUSA300\_1667 & hypothetical & putative glycerophosphory! diester phosphodiesterase & 11.30 \(\pm\) 7.51 \\ SAUSA300\_0994 & _pdhB_ & pyruvate dehydrogenase E1 component, beta subunit & 11.20 \(\pm\) 8.12 \\ SAUSA300\_0974 & _purN_ & phosphoriology!lyficamide formyltransferase & 11.07 \(\pm\) 8.08 \\ SAUSA300\_0067 & hypothetical & universal stress protein & 11.02 \(\pm\) 9.02 \\ SAUSA300\_1590 & _rsh (relA)_ & GTP pyrophosphokinase & 10.95 \(\pm\) 7.18 \\ SAUSA300\_0526 & hypothetical & methyltransferases small subunit & 10.80 \(\pm\) 10.78 \\ SAUSA300\_0952 & hypothetical & aminotransferase, class I & 10.57 \(\pm\) 6.79 \\ SAUSA300\_1694 & _trmB_ & tRNA (guanine-N(7)-)-methyltransferase & 10.55 \(\pm\) 16.08 \\ SAUSA300\_0041 & hypothetical & hypothetical protein & 10.41 \(\pm\) 2.09 \\ SAUSA300\_1449 & hypothetical & Mutf/ mutk family protein & 10.11 \(\pm\) 13.24 \\ SAUSA300\_0724 & hypothetical & hypothetical protein & 10.06 \(\pm\) 2.60 \\ SAUSA300\_1757 & _splB_ & serine protease SplB & 9.41 \(\pm\) 4.17 \\ SAUSA300\_0476 & hypothetical & hypothetical protein & 9.18 \(\pm\) 8.05 \\ SAUSA300\_2052 & hypothetical & single-stranded DNA- binding protein family & 9.11 \(\pm\) 18.19 \\ SAUSA300\_2176 & _cbiO_ & cobalt transporter ATP-binding subunit & 9.03 \(\pm\) 9.11 \\ SAUSA300\_1112 & _styl_ & protein phosphatase 2C domain-containing protein & 8.98 \(\pm\) 14.19 \\ SAUSA300\_0789 & hypothetical & putative thioredoxin & 8.89 \(\pm\) 18.33 \\ SAUSA300\_0379 & _alpF_ & alkyl hydroperoxide reductase subunit F & 8.46 \(\pm\) 4.49 \\ SAUSA300\_0348 & _tatA_ & twin arginine-targeting protein translocase & 8.36 \(\pm\) 5.53 \\ SAUSA300\_0469 & _mmV_ & hypothetical protein & 8.35 \(\pm\) 0.35 \\ SAUSA300\_1792 & hypothetical & hypothetical protein & 8.20 \(\pm\) 4.58 \\ SAUSA300\_2061 & _atpH_ & FGFI ATP synthase subunit delta & 7.98 \(\pm\) 1.29 \\ SAUSA300\_1092 & _prprP_ & uracil permease & 7.85 \(\pm\) 2.60 \\ SAUSA300\_0905 & hypothetical & hypothetical protein & 7.61 \(\pm\) 3.76 \\ SAUSA300\_0444 & _glC_ & LysR family regulatory protein & 7.59 \(\pm\) 2.70 \\ SAUSA300\_2646 & _trmE_ & tRNA modification GTPase TrmE & 7.41 \(\pm\) 8.81 \\ SAUSA300\_2105 & _mtlF_ & PTS system, mannitol specific IIBC component & 6.95 \(\pm\) 0.84 \\ SAUSA300\_2486 & _clpL_ & putative ATP-dependent Clp proteinase & 6.73 \(\pm\) 0.02 \\ SAUSA300\_1887 & _prcB_ & geranylgraphy!ly phosphate synthase-like protein & 6.58 \(\pm\) 3.46 \\ SAUSA300\_1653 & hypothetical & metal-dependent hydrolase & 6.25 \(\pm\) 8.63 \\ SAUSA300\_2393 & _opaCa_ & glycine betaine/carnitine/choline ABC transporter ATP-binding & 6.25 \(\pm\) 7.87 \\ SAUSA300\_1183 & hypothetical & 2-oxoglutarate ferredoxin oxidoreductaseuse subunit beta & 6.19 \(\pm\) 1.88 \\ SAUSA300\_0393 & hypothetical & hypothetical protein & 6.18 \(\pm\) 2.30 \\ SAUSA300\_0174 & hypothetical & hypothetical protein & 6.15 \(\pm\) 1.39 \\ SAUSA300\_0841 & hypothetical & hypothetical protein & 5.97 \(\pm\) 2.99 \\ SAUSA300\_1096 & _carB_ & carbamoyl phosphate synthase large subunit & 5.89 \(\pm\) 2.89 \\ SAUSA300\_2593 & hypothetical & hypothetical protein & 5.84 \(\pm\) 3.04 \\ SAUSA300\_0221 & _pflA_ & pyruvate formate-lyase activating enzyme & 5.68 \(\pm\) 18.96 \\ SAUSA300\_0996 & _lpdA_ & dihydroimpedance dehydrogenase & 5.49 \(\pm\) 2.87 \\ SAUSA300\_1992 & _agrA_ & accessory gene regulator protein A & 5.34 \(\pm\) 14.81 \\ SAUSA300\_1147 & _lshUl_ & ATP-dependent protease ATP-binding subunit HsIU & 4.99 \(\pm\) 6.72 \\ SAUSA300\_1120 & _recG_ & ATP-dependent DNA helicase RecG & 4.60 \(\pm\) 0.15 \\ SAUSA300\_2078 & _mrA_ & UDP-N-acetylglucosamine 1-carboxyvinyltransferase & 3.18 \(\pm\) 3.15 \\ SAUSA300\_1583 & _cymR_ & hypothetical protein & 2.48 \(\pm\) 0.46 \\ SAUSA300\_0992 & hypothetical & hypothetical protein & 2.24 \(\pm\) 20.30 \\ SAUSA300\_0634 & _fhnB_ & ferrichrome transport permease flushB & 2.22 \(\pm\) 4.57 \\ SAUSA300\_0750 & _vniA_ & hypothetical protein & 1.88 \(\pm\) 4.32 \\ SAUSA300\_2485 & hypothetical & methylated DNA-protein cysteine methyltransferase & 1.78 \(\pm\) 9.18 \\ SAUSA300\_0426 & hypothetical & hypothetical protein & 0.95 \(\pm\) 5.09 \\ SAUSA300\_2598 & _capA_ & capsular polysaccharide biosynthesis protein Cap1A & 0.85 \(\pm\) 1.11 \\ SAUSA300\_2246 & hypothetical & hypothetical & 0.51 \(\pm\) 16.59 \\ SAUSA300\_2518 & hypothetical & hydrolase family protein & 0.42 \(\pm\) 7.59 \\ SAUSA300\_0355 & hypothetical & acetyl-CoA acetyltransferaserase & \(-\)0.68 \(\pm\) 4.44 \\ SAUSA300\_0398 & hypothetical & superaemia-like protein & \(-\)0.83 \(\pm\) 2.42 \\ SAUSA300\_2226 & _moB_ & molybdenum cofactor biosynthesis protein B & \(-\)1.15 \(\pm\) 5.09 \\ SAUSA300\_0945 & hypothetical & isochorismate synthase family protein & \(-\)1.17 \(\pm\) 14.05 \\ \hline \hline \end{tabular}
\end{table}