## 3 Results and Discussion  
### Selection of the FSI Calculation Method  
Table 3 summarizes the results obtained with 5 different calculation methods applied to a 400 \(\upmu\)m 3D scaffold. Using these results, it was possible to choose the best FSI method that led to the continuation of the study. The K-\(\epsilon\) model was rejected, as its outputs showed noticeable discrepancies compared with those obtained with the rest of the models. Similarly, the Reynolds model was discarded based on the outputs observed in the turbulence graphic. Despite the fact that the remaining three models showed minor differences, the DES model was finally selected, as the other two models (K-\(\omega\) and SAS) provided similar turbulence results. The DES model reached a better performance by considering smaller or lower energy eddies. For each of the materials used in the comparison, the parallel between the DES calculation in the scaffolds containing different pore sizes (300, 400 and 500 \(\upmu\)m) is shown in Figure 4. Despite a higher speed value than reported in previous studies, the used material supported the blood-induced viscous stress in the three configurations of the pores. As the size of the pore increased, the decreasing tendencies in all the physical properties showed significant improvements, resulting in permeability enhancement [17; 18; 19]. It is interesting to observe that the pressure drops as low as 300 \(\upmu\)m for PLA, while PEI turns out to be the highest of all. In all the physical properties studied, PLA shows similar results to PEI, highlighting an improvement in pore size of 400 \(\upmu\)m in viscous tension. This reveals that this pore size could be very suitable for this material. PLA shows improvement ratios between pore sizes in all the properties studied. The Re that were determined taking into account [PERSON]'s law were between 1000-1200 (300 \(\upmu\)m-500 \(\upmu\)m, respectively). The results are based on the parameters obtained from maximum velocities inside different pores. [PERSON] et al., 2021 [34] have evaluated Re for cases of stenosis due to the disparity of the values used in these cases. The values obtained here are significantly higher than those shown in their study. \begin{table}
\begin{tabular}{l c} \hline Tensile Modulus 1 [MPa] & 3310 \\ Tensile Stress 1 [MPa] & 110 \\ Specific Gravity [g/cm\({}^{3}\)] & 1.24 \\ \hline \end{tabular}
\end{table} 
Table 2: PLA biocompatible used in this study. \begin{table}
\begin{tabular}{c c c c c} \hline \hline
**K-\(\epsilon\)** & **K-\(\omega\)** & **Reynoldss** & **SAS** & **DES** \\
**Realizable** & **SST** & **Stress-\(\omega\)** & **SAS** & **K-\(\omega\) SST** \\ \hline \hline \end{tabular}
\end{table} 
Table 3: Comparative results of the physical properties obtained when 5 different methods were applied. Furthermore, plots included in Figure 3 illustrate the comparative results for each property. Figure 4: Comparative graphic representation of the results obtained for each physical property and pore sizes evaluated and applied on each material (PEI-ULTEM 1010 and PLA). Figure 3: Graphic representation of the quantitative results obtained for each physical property evaluated. However, the parameters considered by these authors would not be similar to the case studied in this paper. This trend also indicates that if the size of the pore increases, the flow within becomes more turbulent. Nevertheless, the size of the pore shall be chosen according to biochemical criteria and convenience for cell growth, as the larger the pores, the more difficult it is for the cell to find a stable and inductive specific surface to reproduce. The observation shows the influence of the surface on the scaffold at regular intervals of cell growth and how the size of the pores progressively diminishes.