###### Abstract  
This study's goals were to determine the health status of a group of heart transplant recipients (HTRs) and their level of physical activity and to compare the health status among them and with a group of healthy sedentary individuals. Fifty-four HTRs and eighteen sedentary individuals (S) were assigned to four groups, according to their level of physical activity (determined with the International Physical Activity Questionnaire); patients with a low, moderate, and high level of physical activity (HTRL, HTRM, and HTRH, respectively) and S participants underwent a basic blood analysis and several tests to assess their cardiovascular, neuromuscular, and functional mobility condition and their quality of life. The S and HTRH were very similar in terms of BP, HR, and blood analysis while HTRM and HTRL differed from both S and HTRH in these parameters. Regarding the cardiovascular, neuromuscular, functional mobility, and quality of life variables assessed in this study, HTRH showed the best results across all of them, followed by S, HTRM, and HTRL. It is suggested that the weekly level of physical activity of HTRs should be high, which might help them to enhance their health and quality of life.  
heart transplant; exercise; cardiovascular function; neuromuscular function; functional mobility condition; quality of life +
Footnote †: journal: Medical  
recipients. [PERSON] et al. (2015) [6] demonstrated how blood pressure values improved in heart transplant patients after twelve weeks of resistance training. [PERSON] et al. (2017) [7] evaluated the effects of high-intensity interval training in a group of forty-one heart transplant patients for five years and observed that their anxiety levels decreased. [PERSON] et al. (2018) [8] detected the relationship between good physical capacity after heart transplantation and long-term survival, finding that high-intensity interval training produced superior effects compared to conventional moderate exercise. [PERSON] et al. (2020) [9] observed that resistance and strength training can greatly improve muscle function and maximal aerobic performance in heart transplant patients, and it can reduce the side effects of immunosuppressive therapy and control risk factors for cardiac allograft vasculopathy. Nonetheless, the health status of HTRs in relation to their level of physical activity ((PA), low, moderate, or high) remains unknown. This information would be relevant and valuable for researchers and professionals. Among other key utilities, it would provide a deeper understanding of the effect of the exercise on HTRs, guide the design of interventional studies aiming to assess the effect of different training protocols and optimize the supervised exercise that they must perform (e.g., addressing the exercise to higher or lower intensity and volume, in more or fewer sessions per week).  
Thus, considering the importance of physical exercise as a non-pharmacological therapy for HTRs and the lack of studies examining the health status of these patients in relation to their PA level, the objectives of this study were to assess the health status of a group of HTRs and their PA level and to compare their health status with that of a group of healthy sedentary individuals (S). It was hypothesized that HTRs with higher levels of PA would exhibit better health statuses than those with moderate or low PA levels, and similar health statuses to the sedentary group.