# Emerging Trends in Research on Food Compounds and Women's Fertility: A Systematic Review
## 3 Results
\begin{table}
\begin{tabular}{c c c c} \hline \hline
**Study** & **Sample** & **Assessment Tool** & **Results** \\ \hline \hline \multicolumn{4}{c}{**Folate**} \\ \hline
**[PERSON] et al.** & \multirow{4}{*}{n = 304 ART} & FFQ & \multirow{4}{*}{Supplemental folate intake} \\
**2019**[34], **USA** & & residence-based daily & \\
**[PERSON] et al.** & & nitrogen dioxide (NO\({}_{2}\)), & \\
**2019**[34], **USA** & & ozone, fine particulate, and & \\  & & black carbon & \\  & & concentrations & \\ \hline
**Minguez-Alarón** & \multirow{4}{*}{n = 178 ART} & FFQ & High BPA was associated with a lower probability of \\
**et al.** & & Urinary BPA & implantation among women with \(<\)400 ug/day intake \\
**USA** & & of folate, but not among women with \(\geq\)400 ug/day \\ \hline
**[PERSON] et al.** & \multirow{4}{*}{
\begin{tabular}{c} \(n=132\) healthy \\
**[36], USA** \\ \end{tabular} } & Serum 25(OH)D, 24h diet & Women with vit. D intake below EAR and serum \\  & & & recalls every 3 months \\
**[PERSON] et al.** & \multirow{4}{*}{n = 16212 infertile} & Vitamin D fortification in \\
**[49], Denmark** & & margarine (mandatory in \\  & & the nation since 1985) & Exposition to fortified margarine was associated \\ \hline \multicolumn{4}{c}{**Antioxidants**} \\ \hline
**[PERSON] et al.** &
\begin{tabular}{c} \(n=150\) healthy \\
**Rusia** \\ \end{tabular} &
\begin{tabular}{c} \\ \(n=169\) pregnant \\
**n = 75 miscarriage** \\
**n = 91 primary** \\
**infertility** \\ \end{tabular} &
\begin{tabular}{c} Serum metal levels \\
**Iron, copper, manganese** \\
**inductive health problems** \\ \end{tabular} \\ \hline
**[PERSON] et al.** 2019**[37], **USA** & \
\begin{tabular}{c} \(n=349\) ART \\ \end{tabular} & FFQ &
\begin{tabular}{c} There were inverse associations of \(\beta\)-carotene intake \\ from foods and of lutein and zexaanthin intake with \\ live birth rates. Total consumption of vitamins A, C, and E before infertility treatment was not associated \\ with live birth rates. \\ \end{tabular} \\ \hline
25(OH)D-25-_hydroxyvitamin D, ART_—Assistive Reproductive Technologies_, AMH—Anti-Mullerian Hormone, FSH—Follicle-stimulating Hormone, FFQ—Food Frequency Questionnaire, EAR—Estimated Average Requirement, BPA—Bisphenol A, FA—fatty acid, IVF—In Vitro Fertilization, ICSI—Intracytoplasmic Sperm Injection. \\ \hline \hline \end{tabular}
\end{table} 
Table 2: Quantitative studies concerning bioactive food components and female fertility qualified for the review. \begin{table}
\begin{tabular}{c c c c c c c} \hline \hline
**Study** & **Treatment** & **Sample** & \begin{tabular}{c} **Clinical** \\ **Pregnancy** \\ **Rate [\%]** \\ \end{tabular}  & \begin{tabular}{c} **Embryo** \\ **Quality** \\ \end{tabular}  & \ \begin{tabular}{c} **Fertilisation** \\ **Rate [\%]** \\ \end{tabular}  & \begin{tabular}{c} **Live** \\ **Birth** \\ **Rate [\%]** \\ \end{tabular}  \\ \hline
**[PERSON] et al. ** & \multirow{4}{*}{ \begin{tabular}{c} Coenzyme Q10 600 mg/day 60 days \\ preceding IVF \\ \end{tabular}  } & Control group n = 93 & \multirow{4}{*}{25} & 0 (0.17.5) & 45 & 22 \\
**2018**[48], **China** & & & Study group n = 76 & \multirow{4}{*}{32} & 1 (0;2) & 67 & 32 \\  & & poor ovarian response & & 2.3 & \multirow{4}{*}{51.1} & 50 \\
**[PERSON] et al. ** & \multirow{4}{*}{\ \begin{tabular}{c} Melatonin \\ 3 mg/day and 6 mg/day for 40 days \\ \end{tabular}  } &
\begin{tabular}{c} Melatonin \\ subjected to 2 nd IVF: \\
**no melatonin n = 10** \\
3 mg/day n = 10 \\
**6 mg/day n = 10** \\
**[PERSON] et al. ** & Multiple micronutrient supplement \\ \begin{tabular}{c} 20 \\ (7.4) \\ \end{tabular}  \\
**[PERSON] et al. ** & \multirow{4}{*}{ \begin{tabular}{c} Vitamin E, 400 mg/day and vitamin \\ D3, 50,000 IU/one in two weeks, \\ placebo 8 weeks \\ \end{tabular}  } & \begin{tabular}{c} 62.1 \\ \(\text{n = 52}\) \\ Placebo n = 53 \\ Women scheduled for \\ ICSI \\ \end{tabular}  & \ \begin{tabular}{c} 71.20\% \\ (7.4) \\ \end{tabular}  &
**[PERSON] et al. ** & \multirow{4}{*}{