# Evaluation of Blue(r)m Mouthwash vs. Chlorhexidine
## 4 Discussion
[31] reported that Blue(r)m mouthwash was effective in managing both gingivitis and periodontitis when used as an adjunct to mechanical debridement, allowing for achieving a reduction of inflammation following the use of Blue(r)m topical oxygen-therapy-based products (toothpaste, mouthwash, and oral gel). The present study tested Blue(r)m mouthwash efficacy in patients with gingivitis in regard to PI, GI, and BOP indices. Despite the plaque reduction at the two-week interval being similar in both the groups, after 30 days, the use of Blue(r)m mouthwash resulted in asignificantly greater reduction in the plaque index than after using chlorhexidine mouthwash. While assessing the gingival index, the reduction after using Blue(r)m mouthwash was similar to the one after chlorhexidine both at the 14 th day and at the one-month intervals. The same observation was made in terms of a reduction in the bleeding on probing sites, wherein the reduction in both the groups was similar and comparable. Our findings corroborate the results of the study conducted by [PERSON] et al. in 2023 [19] which evaluated the efficacy of Blue(r)m mouthwash in reducing plaque calculus and gingival inflammation in comparison to chlorhexidine. The study recruited 20 patients with chronic generalized gingivitis who were asked to rinse their mouths with the respective mouthwashes for one minute, twice daily, for 21 days. The authors concluded that there were no statistically significant differences in efficacy with the Blue(r)m and chlorhexidine mouthwashes in regard to reducing the plaque index, Oral Health Index (OHI), and modified gingival index after 3 weeks of usage. An interesting study was conducted by [PERSON] et al. [32], who evaluated the effect of Blue(r)m mouthwash, used by patients as a mouth wash before ultrasonic scaling, on microbial load in the aerosol produced during ultrasonic scaling. It was concluded that Blue(r)m had a significant effect on reducing bacterial load in the ultrasonic-scaling-induced aerosol when compared to chlorhexidine. In our study, Blue(r)m mouthwash was well tolerated by all the patients and negligible adverse effects were reported by the participants. In a nutshell, chlorhexidine was found to be the superior mouthwash in terms of reducing plaque and the gingival index, as well as a percentage of the bleeding on probing sites, till the second week of the experiment, while the Blue(r)m mouthwash was found to be more effective than chlorhexidine at the end of the month in terms of reducing plaque. The results of the current study should be considered carefully due to the study's limitations, which include its small sample size, short follow up period, as well as the fact that the study was conducted at a single center. Additionally, a microbial analysis could have been performed to assess bacterial load after using Blue(r)m mouthwash and comparing it with other agents and types of oral hygiene products. Moreover, the studies focusing on the cytotoxicity of oxygen-releasing oral antiseptic products should be continued [17; 33; 34]. In the future, long-term, multicenter studies involving different groups of populations should be conducted in order for Blue(r)m to be considered as an alternative to chlorhexidine.