###### Abstract  
The gas turbine blades are scoured by high temperature gas sustainedly and long-term in harsh environment. It is of great significance to explore effective cooling methods to lower the turbine blade temperature so as to ensure safe and stable operation of the gas turbine. However, there are few studies on the cooling channel considering the turning vane, variable cross-section characteristics, and rotation effect. In this paper, five kinds of serpentine cooling channel models with variable cross-section properties and different thickness guide vanes are constructed. The effects of different thickness guide vanes on the overall performance of the channel under stationary and rotating conditions are discussed and compared by numerical method. in surface and investigated their heat transfer variation under stationary conditions. [PERSON] et al. [8] studied the turbulent heat transfer in diverse ribbed channels. In recent years, the dimple and protrusion structures have been favored by researchers due to their high efficiency and low resistance characteristics. [PERSON] et al. [9] studied the turbulent friction and thermal transmission features of the channel with dimples. [PERSON] et al. [10] researched the effect of Reynolds number on channels with teardrop-shaped and spherical dimples based on experiments. [PERSON] et al. [11] studied the enhanced heat exchange and resistance performance in a channel with a single-sided socket structure. [PERSON] et al. [12; 13] researched the \(Nu\) and dimple depth effects on channel behavior. [PERSON] et al. [14] investigated the channel comprehensive performance with dimple construction and V-shaped rib. [PERSON] et al. [15] researched the influence of suction hole and dimple structure on flow properties of a U-shaped channel. Owing to the sophisticated flow characteristics, the turning region has a non-negligible impact on the overall cooling behavior of the channel. The arrangement of turning vanes is conducive to strengthen the heat transfer capacity, and scholars have conducted much research on this. [PERSON] et al. [16] explored the thermal exchange properties of U-shaped channels with ribs and turning vanes on different Prandtl Numbers. [PERSON] et al. [17] researched the discrepancy of cooling efficiency in the blade cooling channel after arranging the turning vane. [PERSON] et al. [18] investigated the effect of the turning vane on the thermal exchange capacity of the tip surface. [PERSON] et al. [19] measured the cooling performance of a three-pass channel with turning vanes. [PERSON] et al. [20] analyzed the cooling properties of the channel with diverse shape and location turning vanes. [PERSON] et al. [21] studied the turning vane impact on the thermal performance in the turning zone. Furthermore, the Coriolis force and centrifugal force generated by rotation will exert a great influence on the thermal properties of the channel in the actual operation of the blade. Therefore, owing to obtain the thermal properties accurately, scholars have carried out in-depth research on the cooling channel performance under rotation effect. [PERSON] et al. [22] computed the cooling properties in two-passage channels in the \(Ro\) range of 0-0.28, which \(AR\) of the channel is 1:1, 1:2, and 1:4, respectively. [PERSON] et al. [23] comprehensively considered the effects of ribs, dimples, and protrusions structure and revealed the channel cooling performance difference under rotating condition. [PERSON] et al. [24] studied a rotating U-shape channel with ribs when \(Re\) was high. [PERSON] and [PERSON] [25] discussed the channel orientation impact of a U-shaped channel with ribs when rotating. [PERSON] et al. [26] analyzed the heat exchange and resistance difference of both two-pass channel and the four-pass snake channel with different turning structures under rotating condition. According to the above literature, numerous studies have been performed on the structure of the cooling channel in blade, and plenty of breakthroughs have been obtained.