## 3 Results
### Characterization of Normal Liver Structures and Liver Tissue Integrity
\begin{table}
\begin{tabular}{c c c c} \hline \hline
**Case Number** & **Surgical Specim Type** & **Indication** & **Final Diagnosis** \\ \hline
1 & Total hepatectomy & \
\begin{tabular}{c} ALD-related cirrhosis \\ (transplantation) \\ \end{tabular} &
\begin{tabular}{c} Cirrhosis with grade 1 steatosis and \\ bilirubinostasis \\ \end{tabular} \\ \hline
2 & Total hepatectomy & \
\begin{tabular}{c} DILI (Anakina)-related acute liver failure \\ (transplantation) \\ \end{tabular} &
\begin{tabular}{c} Acute hepatitis, necroinflammatory + cholestatic \\ pattern, with submassive hepatic necrosis \\ \end{tabular} \\ \hline
3 & Total hepatectomy & Discarded donor liver & Moderate sinusoidal dilatation \\ \hline
4 & Total hepatectomy & \
\begin{tabular}{c} MASLD-related cirrhosis with HCC \\ (transplantation) \\ \end{tabular} &
\begin{tabular}{c} 1.6 cm HCC \\ Cirrhosis with grade 1 steatosis \\ \end{tabular} \\ \hline
5 & Partial hepatectomy & ICC on HCV-related cirrhosis &
\begin{tabular}{c} 4.8 cm ICC. Advanced fibrosis (F3) without \\ necroinflammatory activity \\ \end{tabular} \\ \hline
6 & Total hepatectomy & \
\begin{tabular}{c} AIH-related cirrhosis \\ (transplantation) \\ \end{tabular} &
\begin{tabular}{c} Cirrhosis with moderate necroinflammatory \\ activity, plasma cells and bilirubinostasis \\ \end{tabular} \\ \hline
7 & Partial hepatectomy & ICC in a MASLD-related cirrhosis &
\begin{tabular}{c} 2.7 cm ICC \\ Cirrhosis with grade 1 steatosis \\ \end{tabular} \\ \hline
8 & Total hepatectomy & \
\begin{tabular}{c} ALD-related cirrhosis \\ (transplantation) \\ \end{tabular} &
\begin{tabular}{c} Inactive cirrhosis \\ \end{tabular} \\ \hline
9 & Partial hepatectomy & ICC on a steatotic liver & 6.9 cm ICC. Grade 1 steatosis \\ \hline
10 & Total hepatectomy &
\begin{tabular}{c} DILI vs. AIH related acute liver failure \\ (transplantation) \\ \end{tabular} & Acute hepatitis, necroinflammatory pattern with  bridging confluent necrosis \\ \hline
11 & Partial hepatectomy & ICC on HCV-related cirrhosis & 1.8 cm ICC. Inactive cirrhosis \\ \hline
12 & Partial hepatectomy & HCC on HCV-related cirrhosis. &
\begin{tabular}{c} 1.7 cm HCC \\ Inactive cirrhosis \\ \end{tabular} \\ \hline
13 & Total hepatectomy & \
\begin{tabular}{c} HBV-related cirrhosis with HCC \\ (transplantation) \\ \end{tabular} &
\begin{tabular}{c} 3 and 1.3 cm HCC. Cirrhosis with slight \\ necroinflammatory activity \\ \end{tabular} \\ \hline
14 & Partial hepatectomy & Complex liver mass & 5.2 cm mature cystic teratoma \\ \hline
15 & Partial hepatectomy & Left lobe mass in a MASLD-related & 1.6 cm ICC \\ Cirrhosis & Cirrhosis with grade 3 steatosis & Cirrhosis with grade 3 steatosis \\ \hline
16 & Partial hepatectomy & HCC on a HBV and enol related cirrhosis & 4.6 cm HCC. Advanced fibrosis (F3), without \\  & & &
\begin{tabular}{c} necorin Inflammatory activity \\ \end{tabular} \\ \hline
17 \(\dagger\) & Partial hepatectomy & Right lobe mass on HCV chronic hepatitis &
\begin{tabular}{c} 5 cm HCC. Advanced fibrosis (F3), without \\ necroinflammatory activity \\ \end{tabular} \\ \hline
18 \(\dagger\) & Partial hepatectomy & Right lobe mass on HCV chronic hepatitis &
\begin{tabular}{c} 5 cm HCC. Advanced fibrosis (F3), without \\ necroinflammatory activity \\ \end{tabular} \\ \hline
19 & Total hepatectomy & \
\begin{tabular}{c} MetALD-related cirrhosis with HCC \\ (transplantation) \\ \end{tabular} &
\begin{tabular}{c} Multifocal HCC \\ Inactive cirrhosis \\ \end{tabular} \\ \hline
20 & Partial hepatectomy & CRC metastasis & 3.6 cm CRC metastasis. Grade 1 steatosis \\ \hline
21 & Total hepatectomy & \
\begin{tabular}{c} ALD-related cirrhosis with ablated HCC \\ (transplantation) \\ \end{tabular} &
\begin{tabular}{c} 3.5 and 2 2 necrotic lesions (treated HCC). \\ Cirrhosis with slight necroinflammatory activity \\ \end{tabular} \\ \hline
22 & Total hepatectomy & \
\begin{tabular}{c} Hepatorenal polycystic disease \\ (transplantation) \\ \end{tabular} &
\begin{tabular}{c} Polycystic liver \\ \end{tabular} \\ \hline
23 & Total hepatectomy & \
\begin{tabular}{c} AIH-related acute liver failure \\ (transplantation) \\ \end{tabular} &
\begin{tabular}{c} Acute hepatitis, necroinflammatory pattern, \\ with submassive hepatic necrosis \\ \end{tabular} \\ \hline \hline \end{tabular}
\end{table}