## 1 Introduction  
Taiwan has a geographic location and environment conducive to aquaculture development. Aquaculture in Taiwan has a long history of more than three centuries, and it has rapidly expanded, diversified, intensified, and technologically advanced from 1960 to the 1990s [1]. Despite Taiwan's land and water resource limitations, it is one of the major aquaculture producers in the world; therefore, it was once called the \"kingdom of aquaculture\" [2]. Until now, over 35 major and candidate species have been cultured for commercial purposes [3]. The average revenue of Taiwan from aquaculture reached US $11 billion between 2010 and 2015 [3]. Moreover, the annual aquaculture production was approximately 300,000 t during the 2010s. Specifically, shrimp culture production has been notable because Taiwan's government has strongly supported aquaculture since the 1980s [4], in particular, aquaculture of shrimp--including whiteleg shrimp (_Litopenaeus vannanei_), grass shrimp (_Penaeus monodon_), giant river shrimp (_Macrobrachium rosenbergii_), sand shrimp (_Metapenaeus ensis_), and kuruma shrimp (_Penaeus japonicus_). Moreover, the average revenue from the shrimp aquaculture industry reached US $3000 million between 2010 and 2016. Intensive and large-scale breeding is preferred by aquaculture farmers in Taiwan because the farmers are limited to land use [5]. Moreover, their farms are generally situated near residential and agricultural areas, which makes biological control difficult [6]. The cultured species became more susceptible to bacterial, viral, parastical, and fungal infections, necessitating the use of various veterinary drugs for the prevention and treatment of these infections. However, when such drugs are heavily employed in aquaculture, aquaculture products may contain drug residues, potentially exposing the consumers of the products to these residues. This has an inadvertent ecological impact and raises health concerns such as increased risk of allergies, carcinogen exposure, and the development of bacteria resistant to antibiotics [5]. Because of their benthic feeding behavior, shrimp can be used to indicate the levels of chemicals in aquatic environments [7]. Analyzing the amounts of pollutants in shrimp indicates the environmental levels of veterinary drugs and the extent to which drugs are transferred through the trophic chain. In Taiwan, shrimp are the crustaceans cultured most extensively in land-based ponds [3], and in the inner regions of the island, shrimp are generally bred in a mix with other aquatic products. Typically, veterinary drugs are used to prevent or treat diseases in nonshrimp targets, which pollutes water and soil environments while contaminating shrimp. In this regard, shrimp products have played a crucial role in seafood safety. Residues of veterinary drugs in shrimp are a crucial concern regarding public health, especially when the residues are of banned chemicals that have been employed illegally. Therefore, in this study, we detected in shrimp samples the levels of the following banned veterinary compounds in Taiwan: leucomalachite green (LMG), malachite green (MG), nitrofuran metabolites, and chloramphenicol. These compounds' maximum residue limits (MRLs) in shrimp have not been established by the Taiwan Food and Drug Administration (TFDA). In addition, we detected florfenicol, thiamphenicol, and quinolone residues, including danofloxacin, diffusacin, enrofloxacin, flumequine, and sarafloxacin, in shrimp. The TFDA defined the MRL levels of these quinolones in livestock and chicken in 2018; however, the use of these compounds in the cultivation of shrimp is banned. The present study's detection of the residues of these compounds in shrimp thus indicates the degree of legal compliance regarding the use of these products. In addition, the seafood-consumption-based estimated daily intake (EDI) of these contaminants was determined to identify the effects of exposure to these veterinary drugs on the health of the Taiwanese public.