# Biological Activities of Selected Medicinal and Edible Plants Aqueous Infusions
## 3 Results and Discussion
### Antiproliferative Activity of Aqueous Herbal Infusions
\begin{table}
\begin{tabular}{c c c c c} \hline \hline
**Sample (g/L)** & \multicolumn{4}{c}{**Inhibition of Cell Proliferation (\%)**} \\ \hline  & & & t/h & \\ \hline
1.00 & 4 & 24 & 48 & 72 \\ \hline _Geranium macorrhizum_ & 15.82 \(\pm\) 1.06 *** & 17.03 \(\pm\) 2.92 \({}^{\text{b}}\) & 40.48 \(\pm\) 0.46 \({}^{\text{a}}\) & 54.99 \(\pm\) 2.80 \({}^{\text{a}}\) \\ _Verbascum thapsus_ & 12.33 \(\pm\) 3.00 \({}^{\text{ab}}\) & 12.64 \(\pm\) 2.24 \({}^{\text{c}}\) & 16.60 \(\pm\) 1.20 \({}^{\text{d}}\) & 26.79 \(\pm\) 0.70 \({}^{\text{d}}\) \\ _Onontis spitosa_ & 13.61 \(\pm\) 3.10 \({}^{\text{ab}}\) & 19.02 \(\pm\) 0.96 \({}^{\text{b}}\) & 30.11 \(\pm\) 0.85 \({}^{\text{b}}\) & 49.05 \(\pm\) 1.47 \({}^{\text{b}}\) \\ _Achillae millefolium_ & 11.12 \(\pm\) 2.59 \({}^{\text{ab}}\) & 19.61 \(\pm\) 1.94 \({}^{\text{b}}\) & 38.09 \(\pm\) 1.89 \({}^{\text{a}}\) & 48.53 \(\pm\) 3.73 \({}^{\text{b}}\) \\ _Polygosum aviculare_ & 7.95 \(\pm\) 2.45 \({}^{\text{b}}\) & 25.43 \(\pm\) 3.18 \({}^{\text{a}}\) & 27.26 \(\pm\) 0.72 \({}^{\text{c}}\) & 36.30 \(\pm\) 3.03 \({}^{\text{c}}\) \\
0.50 & 4 & 24 & 48 & 72 \\ \hline _Geranium macorrhizum_ & 13.41 \(\pm\) 2.49 \({}^{\text{a}}\) & 16.41 \(\pm\) 1.43 \({}^{\text{ab}}\) & 29.77 \(\pm\) 1.21 \({}^{\text{a}}\) & 46.07 \(\pm\) 1.38 \({}^{\text{a}}\) \\ _Verbascum thapsus_ & / & / & / & / \\ _Onontis spitosa_ & 10.56 \(\pm\) 1.12 \({}^{\text{ab}}\) & 15.41 \(\pm\) 2.39 \({}^{\text{ab}}\) & 30.54 \(\pm\) 2.13 \({}^{\text{a}}\) & 38.05 \(\pm\) 1.17 \({}^{\text{b}}\) \\ _Achillae millefolium_ & 9.71 \(\pm\) 0.43 \({}^{\text{ab}}\) & 13.48 \(\pm\) 2.90 \({}^{\text{b}}\) & 31.70 \(\pm\) 1.78 \({}^{\text{a}}\) & 36.78 \(\pm\) 3.00 \({}^{\text{b}}\) \\ _Polygosum aviculare_ & 8.62 \(\pm\) 2.93 \({}^{\text{b}}\) & 19.07 \(\pm\) 1.27 \({}^{\text{a}}\) & 20.52 \(\pm\) 1.21 \({}^{\text{b}}\) & 28.83 \(\pm\) 1.25 \({}^{\text{c}}\) \\
0.25 & 4 & 24 & 48 & 72 \\ \hline _Geranium macorrhizum_ & 7.35 \(\pm\) 0.88 \({}^{\text{a}}\) & 11.34 \(\pm\) 1.39 \({}^{\text{a}}\) & 27.93 \(\pm\) 1.14 \({}^{\text{a}}\) & 43.98 \(\pm\) 1.36 \({}^{\text{a}}\) \\ _Verbascum thapsus_ & / & / & / & / \\ _Onontis spitosa_ & 8.75 \(\pm\) 1.05 \({}^{\text{a}}\) & 11.69 \(\pm\) 1.04 \({}^{\text{a}}\) & 22.06 \(\pm\) 1.47 \({}^{\text{b}}\) & 37.08 \(\pm\) 2.88 \({}^{\text{b}}\) \\ _Achillae millefolium_ & 10.95 \(\pm\) 3.48 \({}^{\text{a}}\) & 12.74 \(\pm\) 2.45 \({}^{\text{a}}\) & 31.16 \(\pm\) 1.44 \({}^{\text{a}}\) & 40.20 \(\pm\) 3.31 \({}^{\text{ab}}\) \\ _Polygosum aviculare_ & 2.20 \(\pm\) 0.85 \({}^{\text{b}}\) & 12.30 \(\pm\) 1.82 \({}^{\text{a}}\) & 15.60 \(\pm\) 3.31 \({}^{\text{c}}\) & 20.33 \(\pm\) 1.11 \({}^{\text{c}}\) \\
0.10 g/L & 4 & 24 & 48 & 72 \\ \hline _Geranium macorrhizum_ & 2.96 \(\pm\) 0.14 \({}^{\text{b}}\) & 10.57 \(\pm\) 2.87 \({}^{\text{a}}\) & 16.31 \(\pm\) 1.44 \({}^{\text{b}}\) & 22.81 \(\pm\) 2.50 \({}^{\text{b}}\) \\ _Verbascum thapsus_ & / & / & / & / \\ _Onontis spitosa_ & 5.75 \(\pm\) 0.45 \({}^{\text{a}}\) & 13.28 \(\pm\) 3.14 \({}^{\text{a}}\) & 19.56 \(\pm\) 0.94 \({}^{\text{b}}\) & 21.14 \(\pm\) 3.84 \({}^{\text{b}}\) \\ _Achillae millefolium_ & 4.07 \(\pm\) 0.96 \({}^{\text{b}}\) & 9.11 \(\pm\) 1.08 \({}^{\text{ab}}\) & 23.68 \(\pm\) 2.11 \({}^{\text{a}}\) & 30.05 \(\pm\) 1.74 \({}^{\text{a}}\) \\ _Polygosum aviculare_ & 0.41 \(\pm\) 0.58 \({}^{\text{c}}\) & 5.07 \(\pm\) 1.11 \({}^{\text{b}}\) & 9.92 \(\pm\) 2.51 \({}^{\text{c}}\) & 13.47 \(\pm\) 0.70 \({}^{\text{c}}\) \\ Positive control (cisplatin 50 \(\mu\)g/mL) & 13.62 \(\pm\) 2.27 & 20.74 \(\pm\) 1.76 & 50.22 \(\pm\) 0.95 & 79.45 \(\pm\) 1.54 \\ \hline \hline \end{tabular}
\end{table} 
Table 4: In vitro antiproliferative activity (inhibition of cell proliferation (%)) of aqueous infusions at different concentrations from selected plant species against the MD-MBA-231 cancer cells.