sentence: Additionally , rare FTD-causing mutations have been found in : the Valosin gene ( VCP ) , that was first reported to be mutated in families with hereditary inclusion body myopathy with Paget disease of the bone and FTD ; the Charged multivesicular body protein 2B ( CHMP2B ) , with only one proven pathogenic mutation described in 2005 and segregating with FTD ; the TAR DNA binding protein ( TARDP ) and the Fused in Sarcoma ( FUS ) genes , two well established ALS-associated genes , playing a minor role also in FTD ( Pottier et al ., 2015 ) .