sentence: The type I transmembrane receptor Sortilin-related CNS-expressed receptor 2 ( SorCS2 ) , together with SorCS1 and 3 , Sortilin and SorLA constitute the Vacuolar Protein Sorting 10 protein ( VPS10p ) family that is central to many pathways in control of neuronal viability and function , and has been associated with cancer and neurodegenerative diseases such as Alzheimer ’ s and Huntington ’ s .