sentence: Disappointingly , for patients with relapsed NSCLC , transtracheal injection of Adp53 in addition to docetaxel did not improve overall survival or efficacy.43In 2005 , a case report showed a 23-year-old patient with recurrent hepatocellular carcinoma ( HCC ) who was treated with Gendicine combined with transcatheter arterial chemoembolization ( TACE ) .44 A total of 3 × 10 virus particles of Gendicine were infused via the hepatic artery .