sentence: Having said this , it is important to acknowledge that the Grm2 / 3 mouse is not a ‘ disease model ’ in itself ; although there is evidence for the altered dimerisation of mGlu3 in schizophrenia [ 53 ] , neither mGlu2 or mGlu3 are completely absent in the brains of schizophrenia patients.Group II metabotropic glutamate receptors could be relevant to SCRD in neuropsychiatric disorders besides schizophrenia .