sentence: Point mutations in 3A and ACBD3 at the binding interface inhibited the activation of PI4KB ( 17 ) , suggesting that PI4KB recruitment to membranes via 3A-ACBD3-PI4KB interaction is necessary for kobuviruses to exploit PI4KB activity.Enteroviruses also express a viral protein called 3A , but this differs from Kobuvirus 3A both in sequence and in structure .