sentence: Consequently , the significantly increased number of ipsilateral hind paw lifts caused by cold stimulus in the CCI-injured mice from days 17 to 28 after surgery ( p < 0.001 , one-way ANOVA followed by SNK test vs. the corresponding sham-operated mice treated with vehicle ; Figure 1C and Table 1 ) was reduced by oltipraz in a time-dependent manner and was completely normalized after 11 days of treatment .