sentence: In a Phase I study , patients received increasing doses of erlotinib ( 100 – 150 mg / day orally ) and cisplatin ( 30 – 40 mg / m / day intravenously ) for 7 weeks , in combination with a standard radiotherapy regimen ( 1.8 Gy daily [ five fractions / week ] to a total dose of 63 Gy in 7 weeks ) , and the regimen was well tolerated.22A Phase II trial conducted by the Sarah Cannon Oncology Research Consortium investigated combined modality treatment with erlotinib , bevacizumab , chemotherapy , and radiotherapy in patients with locally advanced SCCHN .