sentence: Variants in several loci of the sortilin-related receptor L1 gene ( SORL1 , also known as SORLA , SORLA1 or LR11 ) can increase the risk of AD ( Rogaeva et al ., 2007 ; Pottier et al ., 2012 ; Wen et al ., 2013 ; Felsky et al ., 2014 ; Louwersheimer et al ., 2015 ; Verheijen et al ., 2016 ) .