sentence: Recently , several studies have shown that ABCA1 reduces inflammatory responses by inhibiting the secretion of interleukin-1 β ( IL-1 β ) and tumor necrosis factor ( TNF - α ) and the NF - κ B signaling pathway via the removal of reactive oxygen species ( ROS ) ( Babashamsi et al. 2019 ) , and ABCA1 may be linked to these functions via apoA-I .