sentence: Taken together , these results suggest that the SWI / SNF complex recruits the co-activator p300 to enhancer loci via a direct interaction.To further evaluate how the interaction between SWI / SNF and p300 regulates H3K27ac levels , we immunoprecipitated SWI / SNF complexes using an antibody against the core subunit SMARCC1 and measured histone acetylation activity using recombinant histones as a substrate .