sentence: Recently , analysis of a growth defect of a SixA-null strain identified a different regulatory pathway that appears to be a physiological target of SixA ( 33 ) : the nitrogen-related phosphotransferase system.In contrast to the classical carbohydrate phosphotransferase systems , the nitrogen-related phosphotransferase system does not participate in sugar phosphorylation and uptake , but , like the carbohydrate systems , it regulates a diverse set of cellular processes , including potassium homeostasis , nitrogen and carbon metabolism , the stringent response , and two-component signaling ( 10 , 43 ) .