sentence: Sciatic nerve injury caused a significant increase in the expression of p-JNK ( F ( 2,12 ) = 11.40 , p < 0.002 , one-way ANOVA vs. the sham-operated mice treated with vehicle ; Figure 5A ) , p-ERK 1/2 ( F ( 2,12 ) = 14.79 , p < 0.001 , one-way ANOVA vs. the sham-operated mice treated with vehicle ; Figure 5B ) , and p-P38 ( F ( 2,12 ) = 12.53 , p < 0.001 , one-way ANOVA vs. the sham-operated mice treated with vehicle ; Figure 5C ) in the spinal cord , and these changes were reversed by oltipraz treatment .