sentence: In relation to the NMTs of other kinetoplastids , the residues predicted to form the peptide binding groove in L. donovani NMT ( Fig. 6 ) are fully conserved in the NMTs from the pathogenic Leishmania species L. major , L. infantum and L. braziliensis and different in the NMTs of T. brucei and T. cruzi at two ( Ile328 replaced by Leu and Leu421 by Val ) and four ( Tyr326 replaced by Phe , Ile328 by Leu , Gly234 by Leu , and Gln238 by His ) positions , respectively .