sentence: Wang and colleagues reported the ability of pomegranate extract ( POM Wonderful , Los Angeles , CA , USA ) , a standardized pomegranate extract containing 37 – 40 % punicalagin and 3.4 % free ellagic acid , to induce a potent in vitro cytotoxic effect on metastatic castration-resistant prostate cancer cell lines such as C4-2 ( IC = 42 μ g / mL ) , PC3 ( IC = 78 μ g / mL ) , and ARCaP ( IC = 161 μ g / mL ) [ 83 ] .