sentence: In any case , their high levels of sequence divergence , particularly at the N-terminal region known to harbor the ligand-binding domain in Epa [ 49 ] , suggest they cannot be functionally equivalent.Other genes shown to be involved in virulence in C. albicans and / or C.glabrata , such as the phospholipase B gene , or the Super Oxide Dismutase genes ( SOD genes ) , exhibit variable presence / absence in the Nakaseomyces , with no obvious correlation to pathogenicity of the species .