sentence: Lasso peptides show a variety of biological properties ; bacteriocin-like activity against Gram-negative bacteria caused by those produced by Gram-negative bacteria ( microcin J25 , capistruin and astexins ) and promiscuous activities ranging from microbial activity5678910111213141516 to receptor antagonistic activity171819 and enzyme inhibitory activity2021 caused by those produced by Gram-positive bacteria .