sentence: Because most of the genes required for vacuolar biogenesis and protein transport are conserved between S. pombe and S. cerevisiae ( Takegawa et al ., 2003 ) , it is possible that Sst4 / Vps27 is also a component of endosomal sorting complexes in S. pombe.Spo20 , a phosphatidylinositol / phosphatidylcholine transfer protein of S. pombe , is also notable because some of the abnormal FSM morphologies resembled those of mug28 Δ cells in spo20-KC104 mutant cells ( Nakase et al ., 2001 ) .