sentence: Consistent with the roles of D-type cyclins in mediating the G1 / S transition ( reviewed by Inz é and De Veylder 2006 ) , CYCD2 ; 1 - and CYCD5-associated activities were highest prior to cell division in germinating embryo axis cells ( Guti é rrez et al. 2005 ; Lara-N ú ñ ez et al. 2008 ) .