sentence: Similar interaction mesh images could be produced from confocal images of PGRN associated with plaques from low plaque and high plaque cases.Analysis of interactions of PGRN-immunoreactive structures with neuritic plaques were carried out using markers for pTau ( antibody AT180 ) , pan-neurofilaments ( preferentially phosphorylated neurofilaments ) ( antibody SMI312 ) and synaptophysin .