sentence: Epac1 : exchange protein activated by cAMP ; ER : endoplasmic reticulum ; IP3 : inositol 1,4,5 - trisphosphate ; G β γ G-protein β γ subunits ; GDP β S : guanosine 5 ' - O - ( 2-thiodiphosphate ) ; Gp ( CH ) pp : guanosine 5 ' , α - β - methylene triphosphate ; PKA : protein kinase A ; mSIRK : myr-SIRKALNILGYPDYD-OH ; L9A : myr-SIRKALNIAGYPDYD-OH ; 2-APB : 2-aminoethoxydiphenyl borate ; W-5 : N - ( 6-aminohexyl ) -1 - naphthalenesulfonamide ; 8-pMeOPT : 8-( 4-Methoxyphenylthio ) -2 ' - O-methyladenosine-3 ' ,5 ' - cyclic monophosphate ; β ARK-CT : C-terminal domain of β - adrenergic receptor kinase ; YM58483 : 4-methyl-4 ' - [ 3,5 - bis ( trifluoromethyl ) -1 H-pyrazol-1-yl ] -1,2,3 - thiadiazole-5-carboxanilide ; CRAC : Ca release-activated Ca channels ; TRP : transient receptor potential ; Competing interests .