sentence: To further assess how c-di-GMP impacts early sporulation events , we measured the transcript levels of additional early-sporulation-specific genes , including spo0A , murG ( a Spo0A-dependent gene ) , sigF ( encodes the early sporulation-specific sigma factor that is expressed in the forespore compartment ) , gpr ( a SigF-dependent gene ) , and spoIID ( a SigE-dependent gene ) .