sentence: The significant difference was observed on inter-comparison of the VEGF expression in the connective tissue of KCOT and DC , whereas no significant difference was observed in the VEGF expression in the connective tissue of KCOT and DC. Conclusion :. The present study data supports the literature finding that angiogenesis can be important in the progression and enlargement of odontogenic cysts similarly to what occurs in neoplastic conditions and further it can be concluded that the higher positivity for VEGF of KCOT could help to explain in part the aggressive biological behavior of the lesion .