sentence: The msr family ABC-F type ribosomal protection gene , which is homologous to the coding sequence of MrsE ( 99 % query coverage , 79 % similarity ) , encodes resistance to streptogramins , phenicols , pleuromutilins , lincosamides , oxazolidinones , tetracyclines , macrolides and other antibiotics which target the peptidyl-transferase region of the ribosomal subunit .