sentence: There is now good evidence that , besides triggering mRNA degradation ( in a slicer-dependent or - independent manner ) , the ( mi ) RISC can also cause translation repression of polyribosomal transcripts , in some cases without or with minimal mRNA destabilization , in animals , plants , and some protists like the alga C. reinhardtii ( 2 , 4 , 6 , 11 , 13 ) .