sentence: However , it was notable that the magnitude of the effect of tiotropium / olodaterol compared with tiotropium monotherapy for the risk of first moderate-to-severe COPD exacerbation in this study was consistent with that observed in the DYNAGITO Japanese subpopulation ( current study : HR : 0.85 ; 95 % CI : 0.63 – 1.15 ; DYNAGITO Japanese subpopulation : HR : 0.81 ; 99 % CI : 0.57 – 1.17 ) .