tokens: Freshly isolated T cells from lupus patients , rheumatoid arthritis ( RA ) patients , and normal individuals were activated physiologically via the TCR with anti-CD3 and anti-CD28 Abs to assess proximal membrane signaling , and with PMA and a calcium ionophore ( A23187 ) to bypass membrane-mediated signaling events .
folded_tokens: freshly isolated t cells from lupus patients , rheumatoid arthritis ( ra ) patients , and normal individuals were activated physiologically via the tcr with anti-cd3 and anti-cd28 abs to assess proximal membrane signaling , and with pma and a calcium ionophore ( a23187 ) to bypass membrane-mediated signaling events .
labels: O O B-cell_type I-cell_type O B-multi_cell B-multi_cell O B-other_name I-other_name O B-other_name O B-multi_cell O O B-multi_cell I-multi_cell O O O O O B-protein_family_or_group O B-protein_family_or_group O B-protein_family_or_group I-protein_family_or_group O O O O O O O O B-other_organic_compound O O B-other_organic_compound I-other_organic_compound O B-other_organic_compound O O O B-other_name I-other_name I-other_name O