In the video, a man is seen speaking to the camera while holding a piece of paper. He is wearing a blue shirt and tie and is bald. Behind him, there is a screen displaying a graph and some text. The man appears to be giving a presentation or report, as he is looking directly at the camera and appears to be addressing the audience. The graph on the screen shows a downward trend, indicating a decrease in the stock price of Ionis Pharmaceuticals. The text on the screen includes the company's name and the current stock price, which is -0.21. The man seems to be discussing the stock market or financial news, as he is holding a piece of paper that could be a script or notes for his presentation. The overall setting suggests that this is a news broadcast or financial report.