Biopython is vulnerable to doctype XML external entity (XXE) injection through Bio.Entrez
Date: 2025-12
Affected: pip/biopython
Attack vector: other
Category: vulnerability-disclosure
Severity: Medium
CVE: CVE-2025-68463
CWE: CWE-611
CVSS: 4.9 (CVSS:3.1/AV:N/AC:H/PR:L/UI:N/S:C/C:L/I:N/A:L)

Bio.Entrez in Biopython through 1.86 allows doctype XXE.


Mitigations:

Architectural layers (MAESTRO):