Woods Hole is a census-designated place ( CDP ) in the town of Falmouth in Barnstable County , Massachusetts , United States . It lies at the extreme southwest corner of Cape Cod , near Martha 's Vineyard and the Elizabeth Islands .
Woods Hole is a census-designated place and village within the town of Falmouth in Barnstable County , Massachusetts , at the extreme southwest corner of Cape Cod , near Martha 's Vineyard and the Elizabeth Islands .