Among the first to use botulinum toxin ( `` botox '' ) and fillers , Brandt was noted for his role in the FDA approval of numerous fillers and botulinum toxins for cosmetic use in the United States .
He was known for using the first botulinum toxin ( `` botox '' ) and fillers . Brandt was also known for his role in the FDA approval of numerous fillers and botulinum toxins for cosmetic use in the United States .