Coming from modest beginnings in Savona , Liguria , the family rose to prominence through nepotism and ambitious marriages arranged by two Della Rovere popes , Francesco della Rovere , who ruled as Pope Sixtus IV ( 1471-1484 ) and his nephew Giuliano ( Pope Julius II , 1503-1513 ) .
These marriages were arranged by two Della Rovere popes , Francesco della Rovere ( Pope Sixtus IV , 1471-1484 ) and his nephew Giuliano ( Pope Julius II , 1503-1513 ) .