Jerne developed the `` natural selection theory of immunology , '' proposed by Paul Ehrlich 50 years earlier , although he was missing the clonal selection element proposed by David Talmage and then by Frank Macfarlane Burnet .
He developed the `` natural selection theory of immunology , '' which was proposed by Paul Ehrlich 50 years earlier , although he was missing the clonal selection element proposed by David Talmage and later by Frank Macfarlane Burnet .