Charles is perhaps best known as the instigator of the unsuccessful Jacobite uprising of 1745 , in which he led an insurrection to restore his family to the throne of the Kingdom of Great Britain , which ended in defeat at the Battle of Culloden that effectively ended the Jacobite cause .
Charles is perhaps best known as the leading the unsuccessful Jacobite uprising of 1745 , where he led an rebellion which ended in a defeat at the Battle of Culloden that effectively ended the Jacobite cause .