Frederick Akbar Mahomed ( d. 1884 ) , who worked at Guy 's Hospital in London , made substantial contributions to the process of clinical trials , where `` he separated chronic nephritis with secondary hypertension from what we now term essential hypertension .
Frederick Akbar Mahomed ( d. 1884 ) , who worked at Guy 's Hospital in London , made substantial contributions to the process of clinical trials during his detailed clinical studies , where `` he separated chronic nephritis with secondary hypertension from what we now term essential hypertension . ''