A central concept of toxicology is that effects are dose-dependent ; even water can lead to water intoxication when taken in too high a dose , whereas for even a very toxic substance such as snake venom there is a dose below which there is no detectable toxic effect .
Effects are dose-dependent : even water can lead to ` water intoxication ' when taken in too much . For even a very toxic substance such as elapid snake venom there is a dose below which there is no toxic effect .