The Meselson -- Stahl experiment was an experiment by Matthew Meselson and Franklin Stahl in 1958 which supported the hypothesis that DNA replication was semiconservative .
The Meselson -- Stahl experiment was an experiment done by Matthew Meselson and Franklin Stahl in 1958 , using `` E. coli '' DNA . With their experiment , they concluded that DNA replication was semiconservative .