Original: Cairanne is a commune in the Vaucluse department in the Provence-Alpes-C Ã te d'Azur region in southeastern France whose inhabitants were locally nicknamed leis afrontaires de Cairana , the cheeky ones from Cairanne .
Simplified: Cairanne is a commune of 850 people ( 1999 ) . It is located in the region Provence-Alpes-C Ã te d'Azur in the Vaucluse department in the south of France .