Original: Municipios de Puerto Rico y sus centros administrativos ( in Spanish ) The City of Ponce is the second largest city in Puerto Rico outside of the San Juan metropolitan area , and is named after Juan Ponce de León y Loayza , the grandson of Spanish conquistador Juan Ponce de León .
Simplified: Ponce is the second largest city in Puerto Rico outside of the San Juan metropolitan area . The city was named after Juan Ponce de León y Loayza , the grandson of Spanish conquistador Juan Ponce de León .