루트K — 주주총회소집공고 (20220802)
제출인: 루트K

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2.9
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2022?? 08?? 02??

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(???????) http://www.abprobio.co.kr

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(?? ?) 053) 582-8036

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??????? ??°? ???? ????? ???????.

???? ??? ??365???? ???? ??23???? ??? ??19?? ???????????? ????? ???? ????????? ??????? ???? ??????. (????????? ??? ??542????4 ?? ???? ??25???? ?????? ??????? ????? 1% ???? ????????? ??????? ?? ????? ?????????? ????????? ??????? ???? ??????.)

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1. ?? ?? : 2022?? 08?? 23?? (?) ???? 9:00

2. ?? ?? : ???????? ????? ?????? ?????????? 139 ?????????ι???? ???? 3?? ??????

3. ??????????

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??2-1? ??? : ?系??? ?????? ??[????? ??????](????)

??2-2? ??? : ?系??? ?????? ??[????? IAN YAN PUI CHAN](????)

??2-3? ??? : ?系??? ?????? ??[????? EUGENE YAN HO CHAN](????)

??2-4? ??? : ?系??? ?????? ??[????? ROBERT SAMUEL LANGER](????)

??2-5? ??? : ?????? ?????? ??[????? ??????](????)

??2-6? ??? : ?????? ?????? ??[????? ????](????)

??2-7? ??? : ?????? ?????? ??[????? ?????](????)

- ?? 3? ??? : ?и????? ???? ??????????????? ??? ?????? ?????? ??[????? ?????](????)

- ?? 4? ??? : ????????? ???? ?????? ?? [????? ?????](????)

4. ????????? ???? ???

??? ??542???? 4?? ?????? ??????????? ??? ????? ????????? ??????? ?????? ??????????????(???????? ????????)?? ??????????, ????????? ?? ????????? ?????????? ????? ????????? ???????? ??????.

5. ?????????? ???? ??翡 ???? ????

??????? ??? ????????????? ?????????????? ???????? ?????? ????? ?? ???????. ???? ?????????? ?????????????? ??????翡 ???? ?????ø? ??? ??? ??????, ?????? ???? ????????? ??????? ?????? ???? ?????ð?? ??? ?????? ??? ?????? ???? ????? ?? ??????.

6. ??????? ?????? ???

- ??????? : ????? ??? ?????????????

- ????? : ????????????? ??? ???????? ???? ??????(???? ???????? ????, ???峯?? ??? ???????, ???? ?????? ??? ??????? ???? ?? ??????? ???? ÷??) ?? ?????? ?????

(???, 1%???? ????????? ??? ??????? ???????? ???????? ?????? ??????? ??????? ???????? ???????? ??????? ???, ????? ??? ?????? ????? ????????? ??翡 ????? ?????ο? ????? ??????????? ??????????.)

7. ??????? ?? ????????????? ???? ???? : ?????? ??????? ??368????4?? ???? ????????????? ?????????? ??????????? ???? ???? ?????? ??160?? ??5??? ???? ?????????? ?????????? ??? ??????????? ???????? ?????????, ?? ?? ?????? ?????????? ?????????????? ???????????. ?????????? ??????? ???? ????? ???? ????????? ???????? ?????? ??????? ??????? ?????? ?????ð?? ???????????? ??????? ?? ??????.

1) ???????????????????????????????

????? ??? : http://evote.ksd.or.kr

????? ??? : http://evote.ksd.or.kr/m

2) ??????? ??? / ?????????? ?????? : 2022?? 08?? 05?? ????9?? ~ 2022?? 08?? 22?? 17??

(?? ?? 24?ð? ??? ????)

3) ???????? ?????? ???????? ????????? ??? ?? ???? ???? ??? ??? ?????????? ????

- ??????ο? ???????? ???? : ????? ?????????? ??????, ?????????? ???ο?????? ?????? ??

4) ????????? ???: ??????????? ?????? ???? ????? ????????? ?????? ??? ????????? ??????? ???

8. ???????

- ???? ??γ????????(COVID-19)?? ???? ?? ???ĸ? ?????? ????? ????????? ???? ???? ??? ???????? ??????? ????????? ?? ?? ??????, ????? ?????? ????? ??????? ?????? ???? ?? ?? ?????? ????帳???.

- ??γ????????(COVID-19) ???? ??? ?????? ??????? ??????? ??? ??? ?? ??? ??? ??????? ??????? ??????? ?? ??? ???? ????? ??????? ???? ???? ???? ?????? ???????.(??γ?19 ??????? ????, ????? ????? ???????? ???濡 ???? ?????? ?????翡?? ????????.)

- ??? ????????????? ?????? ???????? ???????? ???? ??????? ???? ??????.

2022?? 08?? 02??

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I. ?????? ???? ????????? ?????? ???? ????

1. ?????? ???? ???????

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1
2022-01-14
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2022-01-24
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2022-01-27
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2022-02-24
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2022-03-16
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6
2022-03-23
????? Abpro Corp., ?繫?????? ??
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7
2022-03-29
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2022-03-30
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2022-04-18
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10
2022-05-03
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2022-05-16
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2022-05-27
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2022-05-30
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14
2022-06-08
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2022-06-17
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2022-07-08
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17
2022-07-12
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2022-07-15
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1. ???? ?????? ???????????? ???

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III. ?????????

1. ????? ????

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??????? ?????

1) ????? ???

?? ????

????? ??????? ??? ????? ?????? ????? ????? ??????? ??????? ?????? ?????? ???? ??????. ???? ?????? ????????? ?????? ???????, ?ð?, ???? ??? ???? ??????? ???? ?????????, ????, ?????, ??????? ???? ? ??? ???????? ?????? ???? ????? ???? ????? ?????? ?????? ???? ??????? ????????? ??????. ????? ?????? ??? ????? ???? ????, ?????? ??? ????????? ????????, ????? ?????? ????? ???·? ?????? ??? ???? ??????. ????? ????? ???? ?????? ??? ??????? ???? ??? ????? ?????????? ????? ????????????.

?? ????

??????(Machine Tool)?? "??? ????? ???(Mother Machine)" ??? ??????. ??? ?????? ???? ????? ????? ????? ?????, ????? ??????? ????? ???????? ????????? ????? ??? ??? ???????. ??????? ???????????? ?(Chip)?? ???????? ??????? ?κ??? ??????? ????? ???????? ??????? ??????, ???????? ???????????? ????? ????? ???? ???¸? ??????????? ???????. ???????(ISO)?????? "?? ?????? ????? ?????? ??????, ????? ??? ????? ??????? ??????? ??????? ???????, ??????? ???? ??? ???" ??? ??????? ??????,????????? ????????? ??????(Cutting Machine)?? ???????(Forming Machine)?? ?з???? ?? ???? ????? ???????? ?θ??? ??????. KS(?????????)?????? ?????? ???? ????? ??? ??????? ????, ???? ?? ????? ??????? ?κ??? ?????? ???? ????? ?????? ????? ????? ??????? ??????. ???????? ?????? ?о????, ??????? ????????? ?? KS?? ????? ??????, ?? ??????? ??? ????????? ??????? ???? ?????????.

?? ???

??????? ??????δ? ??????? ????? ????? ???(Mother Machine)???μ? ????????? ??? ?????? ????????? ????? ?????? ????°???? ??????? ??????? ??????? ??????? ???????????? ??? ???? ?? ?? ??????. ???? ???? ??????????? ???????? ???? ????? ????°? ??????? ????? ????? ????????? ?? ????????? ??? ?????μ? ???????? ?????? ???????. ??????? ??????δ? ???, ???, ?????? ????? ????????? ??????? ????????? ????? ??????? ????? ???? ???? ????? ????? ????? ??????, ????????? ??????? ??? ?????? ???? ??????? ?????? ????. ????, ????, ???? ?? ????? ????? ????????, ????? ?? ???????? ????? ?????δн? ????? ??? IT????? ?????? ????? ?????????? ?????? ????? ????? ????? ????? IT??????????????? ????.

2) ????? ???强

??????? ???????? ?????? ?????? ?? ?? CNC??????? ????? ???(NC??????)?? ??? ?????????????, ???????, IT/????-?????????, ?????/??????, ??? ?????????????? ?з? ?? ?? ??????.

CNC??????? ??? ???????? ???? ?? ???, ???? ?????????????? ???????? ???????????? ???? ???? ????? ??? ????? ???????????, IT/????-?????????, ????????? ?? ?????? ??????? ?з? ?? ?? ??????.

????? ???? ???? ????? ????? ?????? ?????? ??????????.

?? ???????????

???? ????????????? ?????? ???????? ????????? ?????? ????? ???????? ????? ???????? ?????? ?????? ?淮??? ????? ????????? ???? ??? ?????? ?????? ?????? ???? ???????????? ??????? ???????.

???????????? ???? ?????? ?????? ???, ???????? ??? ? ??? ????? ????? ?????? ??????, ?????? ???? ?????? ????? ?????? ??????. ???? ?????????? ????? ???? ?????????? ?????? ?淮??? ???? ?????? ?????? ??????, ??????? ?????????? ????? ?????? ???? ?? ?? ??????.

?? IT/????-?????????

???? IT/????-??????????? ??? ??? ???? ?? ?????? ??? ???? ??θ? ?????? ??? ??????????? ??????? ???????? ???? ??????? IT/????-??????????? ? ????? ??????????. ???? IT/????-?????????? ?????? ????????? ???, ?????? ?????? ???? ?????? ??????? ?????????(???)?? ??????????, ????? ???? ?????? ???????? ?????? ???? ????????????? ???? ??????????. ????? ?????? ?????? ???????????? ???????? ? ??? ????????????.

?? ?????????

?????????, ??????????, ????????? ???? ??????????? ????????????? ?????????? ?????? ?淮? ?? ???? ?????? ???? ?????? ??? ?????? ????? ??????, ???? ???????? ??? ???????????? ??? ???? ???????????? ??????? ?????? ?þ??? ??????.

?????????? ?????? ??????? ???? ?????? ???? ??????, ??簡 ??????? ???????????? ??????????????? ????? ????????? ??? IT/????-?????? ?????? ??????? ????? ???? ??????? ???? ?????? ??????.

3) ??????? ???

?????????? ???????? ?????????? IT/????-???????? ???????? ???? ?????????? ???/???? ????? ????? ?????? ??? ???????, ????? ????? ?????????? ??? ??????? ????? ???????. ????, ????????? ???? ??? ???????ι???? ???? ?? ???? ??????? ??? ?????? ?????? ??????, ?????? ??????? ??? ???????? ????? ?????? ???, ??? ????? ??? ???????? ????? ????? ?????? ??????.

???????? ?? ??簡 ??? ??????? ??????????? ????? ???, ? ?????? ????? ???? ???????? ????? ???? ???, ????? ??????? ???? ???? ????? ??? ??????? ????????? ?????? ???? ??????, ??? ??? ???????? IT/????-??????????ĸ? ?????? ???????? ???? ???弼?? ??????? ??????.

??????? ????? ??????? ??????? ????? ????? ???????? IT/????-???????????? ?????????? ??????? ???? ?????? ???????? ??????, ?? ??? ?????? ???? ?????? ???? ???????? ???? ?? ??????.

?? ???????? ????? ??? ?? ???? ???뿡 ???? ??????? ????????? ???? ???????? ????? ?? ??????.
?? ??????? ???? ???????? ?????? ??? ?? ?? ??????. ?? ???? ?Ｚ???? ??????ø????? ??????? ???? ???? ?????? ???? ????????? ????? ???????κ??? ???? ????????????? ???? ???? ???????, ???? ?????þ??? ???? ????? ????? ??????? ???? ?????? ?κ??? ????? ?þ? ???? ?þ??? ???????. ?? ?????? ???濡 ???? ???????ð??? ?þ???? ????? ???????? ????? ?? ??????.
?? ????????? ?????? IT????? ???????? ?????, ????, ??????? ???? ???????? ???? ??ø??? ?????????ν? ????????? ???? ???????? ????? ?? ??????.

4) ??????

?????? ????? ?????? ?????? ??? ??????, ??? ??????????? ???? ???? ?? ????? ???????? ??????? ????? ?þ??? ?????濡 ??? ?????? ?ø???, ??? ?δ??? ????????? ??????? ????? ?????? ????? ????? ?????? ?????????. ?????? ??? IT???? ?? ?????? ?Ｚ?????? ??????? ??????? ??????? ???? ????~???? ?????? ??? ????????? ???? ????? ???????? ??? ???????.

5) ????? ???????????

????? ????????????? ??? ?? ?????? ?з? ?? ?? ??????, ?°?? ??????? ???? ??????? ??°?? ??????????? ???? ??????? ?? ?? ??????.

?°, ???????? ???????? ??????? ????? ??????, ????????? ??? ????? 1?? 10?ð? ?????? ???? ????? ??? 6~8??, 24?ð? ?????? ????????? ??? 4~5?????,????????? ???(?????? ????, ??????????, ???????? ??)?? ???? ??????? 1~2?????? ?? ª???? ?? ??????.

??°, ???????????? ????????? ??????????? ????? ???? ?????? ????濡????, ????? ????? ???? ????? ???????? ?????, ??翡???? ???????? 1?? 1? ???? ???????? ?????? ??????.

6) ???????

?? ???????? ??????????

???????? ???????????? ???? ?????? ????????? ???????? ?????????? ??? ???????? ???? ?? ??????? ????. ????????? ???????? ????? ?????? ????? ??? ?????? ??????? ?????? ?????? ???????? ?? ???????簡 ???????. ??? ???????? ????? ?????? ???????κ??? 15??????. ???, ???? 2012?? 9???? ????????????????? ????? ???? ?? ?? ???? ???? ???? ??? ??? ?? ???????? ???? ?? ?????????? ??? ???? ?±? ??????? ?????ν? ??? ???? ????????¿??? ?????ο? ?? ??????.

?? KCS????(????????????) ????

????????????(KCS???)?? ???????????? ??34???? ?????? ?????? ???????? ?????? ??????????? ?? ??????????????? ???????? ????? ????? ??????????? ????? ???? ?????? ???? ????? ???????? ?????¡???????? ?????????? ?????? ????????????? ?????? ??? ???? ????? ?????????? ??ø? ?? ?? ????? ??? ????????.

??????? ??????????ν?? ??? ??????? ??????? KCS?????? ????? ???????? ??? ?? ?? ??????. ???? ??? ????? KCS?????? ????????? ???????? ??????? ????? ????? ?????? ???? ?????? ???? ????. ???? 2013?? 4???? KCS?????? ??? ???????? ??????? ??????.

?? ?????? ?????????? ??? ????

'???????', '???????н????', '??? ?? ?ð??????' ?? ?????? ?????? ??????(??????? ????)?? ??????? ???? ?????? ?????????? ??????? ????? ISO14955-1(?????? ??? ?????? ???? ?????) ????? ????????????. ??? 2010?? 5?? 1?? ???? ???? ??????? ??????? 4?? ???? ??????? ?? ?????? ISO14955-1 ????? ??? ?????? ?????? ??? 14?? ???? ?? 93%?? 13?????? ???????? ??????? ????????. ??? ?????? ????????, ??? ?? ??????, ?????? ???? ??? ?????? ????????? ???? ??? ???? ????? ?????? ???????.

?? ?????? ?????????? ???????? ????

?????? ?????????? ????????? ErP(The Energy-related Products Directive)?? ???? ???????????????? ?????? ?????? ??????? ???? ????? ??????? ??????. ?? ???? ???????? ?????? ?????? ????? ???? eco-design?? ????? ?????? ??(LCA: Life Cycle Assessment)?? ????? ??????.

???????? ?????? ?о?? ???? ???? ?????? ???????????? ????? ??????? ???? ?? ?????? ???????? ???????? ??????? ????? ???? ????? ????? ?? ?????? ????, ?????? ???? ???? ????? ??? ??????.

?????? ????? ???

1) ????? ???

????? ???????? ????? ?ð??? ???? ???????? ????? ???????? ???? ???????? ?з?????. ??ι? ??? ???? ?? ??? 1~2???? ????? ?????? ???? ???? ???10~15?? ?????? ????? ???? ???? ??????. ????, ??? ??? ???R&D ????????? ??? ???? ????????? ??????μ?, R&D ???? ???? ??? ???????? ????? ???18% ????? ???? ??????. ??????? ???? ?????? ??????? ??? ?????? ??? ??????? ???? ???? ???? ?? ??? ???? ?????? ?????? ???????ν? ????? ????? ????????.
?? ???? ????? ?????? ??????? ???? ??? ????? ????, ???? ??? ????????? ??????? ???? ??? ???????? ????? ?????? ???????? ??????? ????? ??? ?????? ????????. ???????, ?????????? ???? ??? ????????? ??????? ????????? ???????? ????? ?????? ???? ???? ???? ??????? ?????????? ????????. ?????????? ???? ????????? ????? ???????? ??????? ??????? ???, ???1??, ???2??, ???3??, BLA/NDA(Biologic License Application: ???FDA ???? ????? ???????? ???? ?????????/ New Drug Application: ????? ?????? ???? ???????? ?????? ???? ???????)?? ??? ????? ????. ???? ??4?? ?????????? ?з???? ?????? ??????????(PMS: Post-MarketSurveillancd)?? ???? ???????? ?????? ??????? ????뿡 ???? ???? ???????? ??????? ?? ???? ??°? ????? ?????? ?????? ????? ????. (??ι? ??????? ??? ?????????? ?м?, ???????????, 2017.05)

??? r&d ???μ???.jpg
??? r&d ???μ???

???: Pharmaceutical Industry Profile 2012

2) ????? ???强

???? ???? ??????? ?ĸ?¡ ????(Pharmerging Market: ??? ????? ?????? ??? ?ε? ???þ? ?? ???? ???????) ??? ?? ????? ????? ?? 5%?? ????, 2021??濡 ??1.5?? ????? ??? ????????. ???? ???? ?????? ???, EU, ??? ?? ?????? ???? ?????? ??? ?????? ??70%?? ??????? ??????, ?ĸ?¡ ???? ???????? ???? ???????, ???? ?? ??? ???? ???? ?????? ???? ???弼?? ?????? ?????? ???????.
??ι? ???? ???? ???

(???? : ?????, %)

????
2017??
2018??
2019??
2020??
2021??
2022??
2023??

??????

1,142.9

1,206.2

1,250.4

1,318.3

1,385.6

1,452.9

1,518.4

??????

-

5.5

3.7

5.4

5.1

4.9

4.5

(IQVIA Market Prognosis Global, September 2019)
???? ???? ?????? ????? ???? ????? ??? ??? ????? ???? ???????? ?? ?? ??????. ???????? ?α????? ????? ???? ???, ???, ??????? ?? ???μ?????? ???? ??? ???? ?????? ??????? ??????. ???????(WHO)??2020??? ??????, ?索, ?????? ?? ????????? ?? ???? ??????70%?? ?????? ?????? ?????? ?? ???? ?? ??????. ??? ???, ??????? ?? ????????? ??? ?? ???? ?? ??????? ???? ??????? ?? ?????? ???? ???о??? ?????? ??? ????? ??????.

??. ????? ???

??????? ?????

1) ??? ???

???? ???????? ?? ?з??? ???????(MCT) ???? ??????? ????????? ???????? ??????? ??????, ???????? ??/??/???????? ???????? ??? ???????? ???????? ??????? ??????.

???????? ??/??/???????? ?????? ?????? ????????? ?????? ??????(Taper)??? ??? ??????(stroke)????? ?з??? ???, ????????? BT(orNT)30 ????? ????, BT40~50?? ????, BT60 ????? ???????? ?з??? ????. ???? ???? BT30 ????? ??? BT40?? ??????? ??????.

*BT(Bottle grip national Taper shank) : ???????????????

*NT(National Taper shank) : ?????????????

???? IT???????? ???????????, ??? ???????? ??????? ?????? ????????? ?κ???? Unit?????? ????????? ??? ??????, Unit?? ??? ????翡 ????????? ???? ?????? ???, ???????? OEM???? ??? ?????? ????? ???? ??? ?????? ??? ??????.

2) ???? ???

???? ????? ??????? ??????? ????? ????? ???? ?????? ?з??? ??? ?? ?????????.

- 1????:??????(??????+???????)?? ??? ??????? ???

- 2????:??????(?????????+?????????+CNC??????)?? ??? ??????? ???

- 3????:CNC???????? CNC????, CNC??????, CNC?и???, CNC??????, CNC?????, ??????? ???? ??? ???? ??????? ???

1?????? ????? ???????? ???? ???????????? ???? ?????(???), Mazak(???), DMG(????), OKUMA(???), MORI SEIKI(???) ???? ?????? ?????? ?λ???????????, ?????????? ??????.

2?????? ????? ??????? ?????????? ??????????, ???????, ?????, ????????, ????? ???? ??????.

3?????? ????? ??????? ??? ????????? ????? ?????? ?? ?? ???????? ?????? ?з???? ???? ?????? ???? ????? ????? ????? ???????? ???????(??????), ???????н?(??????)?? ???????, ???? ???? ????? ????? ???? ???? ?????? ?????? ?????? ??? ????? ?? ?? ????? ??????? ?λ???????????, ????????? ?? ??????. ???? ???? ???? ????? ???(FANUC), ????(Brother), ????(TSUGAMI), ???? LK ???? ???? ?????? ?????? ???????? ??????? ?????????. 3?????? ????? CNC??????? ????? ??????(?????), ??????????(??????) ???? ??????.

??????? ????? ??? ????? ??????? ??簡 ???????? ?з???? ????? ???(FANUC), ????(Brother), ????(TSUGAMI), ???? LK ?? ????. ?? ?? ???? ??? ?????? ???? ???? ?ε???? ????? ??????? ???? ??? ?????? ???? 1???? ???(FANUC)?? ???? 2?? ????(Brother)????. ???????? ?????? ?????? ???? ?????? ?????? ????? ?? 1,500~3,500?? ?????? ?? 400~800?? ??????? ??????? ???? ??? ?? 100??~300?? ??????? ??? ?? 400????? ?????? ????????.

???????·δ? ????? ???? ????????????? ????????? ??????????? ??(Main) ?????? ??????? ???????, ????? ???? ?? ?? ??? ????Capa?? ???? ???? ???, ????, LK, ??? ?? ??? ?????? ???????????ε? ?? ?? ??????.

?????????δ? ??? ???????? ??????? ????κп??? ?????????? ????????? ??????? ???????? ????? ????? ??? ????? ???? ???? ????? ????? ????? ?????? ??? ????Capa?? ?ø???? ???? ????? ????? ???????? ????? ????? ?? ?? ??????.

3) ?????? ???

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???? ??????? ?????? ???ð? ?Ｚ?????? ?????? ??????? ??? ????? ??????, ?????, ?????? ???IT??????? ??λ????? ???ð? ?Ｚ?????? ???弼?? ??????????? ???? ?? ?Ｚ?????? ?????????? ?????? ??????? ??????? ?????? ?????????? ???????? ?????? ?????? ?? ?????? ???? ??????.

IT????? ????????? ???????? ??簡 ??????? ??? ????????????? ?????? ?????????? ??????? ??????, ????? ??????? ???? ????? ????? ?? ?????? ???? ?????? ??????? ???? ????????? ???? ????? ????? ??? ?????? ?????? ???????????.

?? ????? ?? ???

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IT???

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???????? ???? ?? ??????? 24,000PRM ????????

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??????? ?????? 90% ?? ????/?Ｚ???? ?´? ???????

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?????

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365?? FULL??????? ?? ????? Happy CALL ???

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2013?? 3???η? KCS(????????)?????? ?? KCS???????

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LOHAS?????? ???? ???/???? ??? ???

EU

High Tech ???

????? ?????? ???? ????????? ?? ??????????

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??? ?????? ??????? ??? ?? ??????, OIL ?????????

????? ????

High Tech ?????? ?????? ????

Middle Market, Volume Zone?? ????

???/??? ?? ???

???/??? ???? ???? ??? ????? ???

???????? ?????? ???? ???

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FTA ?????? ???? ?????? ??????? ??? ??????

???? ?³???? ?????? ????

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?????

?????? A/S

A/S?? ????? ?????? ?? 48?ð??? ?? A/S???????

???????

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?????? ????? ???
1) ??? ???

??????? ??????? ??????????, ?????? ?????? ????, ??????? ????, ?????????, ?????? ????? ???? ????? ???? ??'?????? ?????? ????'?? ??????. ?????? ?????? ??????? ?????? ???????? ?????? ??????? ?????? ??? ????? ???? ??????????? ??? ???????? ??? ????, ?????? ??? ?????????, ??????????? ???? ?????? ??????.
1975?? ???ο? ???? ????? ????? ??? ??????2000??뿡 ????? ?????????? ????? ??? ??????????, ????? ??? ?????? ???????? ?????? ? ?κ??? ??????? ??????. Roots Analytics?? ??????, 2024??Top 10 selling ???? ??5?? ?????? ??? ?????? ?????? ????? ?????? ??? ?????? ????/????? ?о翡?? ???????? ??????? ??λ? ??? ??????.
?????????2?? ??? ???? ???? ????? ????? ??? ??? ????????. ????????? ???? ??????1990????? ????????? ???? ???FDA?? ????EMA ?????2009??Removab(??? ???? ?????, ????? ???????). 2014??Blincyto(??????????? ?????? ?????, ????), 2017??Hemlibra(A?? ???? ?????, ?ν?) ?? ??????? ????? ???ε?? ??????. ?????? ????100???? ????? ???? ??? ???? ??? ?÷????? ?????? ?????? ?? ????? 30?????? ??? ?????????? ????????? ??? ????? ??????? ??? ???? ???强?? ??????.

2) ????? ?¡
??簡 ????? ABP-100 ?? ABP-201?? ????????? ???? ???? ??? Abpro Corporation?? ???? ?????? 3???? ??????? ?÷????? TetraBi(????????) ????? ??????? ??????. ??? ???? 1, 2???? ??????? ????? ?????? ?????? ???? ?????? ?????? ??? ???, ???? ??????????? ???? ??? ???? ????? CAR-T(???? ??? ????? T????) ????? ?????? ????, ????? ????, ???? ?? ???? ?????? ??? ?? ?? ???? ?????? ??????.

tetrabi ???? ?? ????.jpg
tetrabi ???? ?? ????

3) ??????????

?? ABP-100
??. ????
ABP-100?? HER2 ??CD3?? ??????? ??? ?????? ??????? ?????????, ????? ??? HER2?? ????????? ??? ????, ?????, ??? ?????? ?? ?????? ????? ??? ???? ?????? ??????.
??. ????? ???? 
???? ?????????? ?? ??? ????? ????? ?? ???? ?????Abpro Corporation???κ??? ?μ???????? ??? ????????? ???, ???, ????? ??????? ??þ? ?? ?????? ???þ?? ??????CIS???? ?? ??? ??????(??48????)????.
??. ??? ????
ABP-100?? ?????, ???? ???? ??????? ??? ??????? ??? ?? ??????? ???? 27?????? ???? ???? ??????, ?? ???? ?? 42,000???? ?????? ?????? ????????. ?? ???????? ?????? ??? ???? 27,510???? ???? ???? ????????? 11,140???? ?????? ?????? ????????. (American Cancer Society, 2019?? ????)

?????? ???? ??? ?α??? 103???????? ?? ?? 74%?? ??þ?? ?????? ???, ???? ???? ??????? ??? ?????????? ??? ??þ? ??? ???? ?????? ????????. ???? ABP-100?? ???? ??? ?? ?????????? ??? ??????? ?? 25?? ????? ??? ?????? ??????? ??????.

?????? ????? ?? ???? ?????.jpg
?????? ????? ?? ???? ?????

???: GLOBOCAN 2018, WHO
??. ??强
?????? ???? ????? ??20%?? HER2?? ???????? ?????? ??????. ABP-100?? ?????? ???? ??? ????, HER2?? ?????? ?? ????????, ?????, ?????, ???, ?????, ??ð?ξ?, ????, ???????? ?? ??? ?????? ????? ??????? ?????? ??? ????????. ???? ??????? ???????? ????? ??? ?????ν?Herceptin ?? ????HER2 ?????????? ?????? ????? ??? ??High HER2+ ??? ??? ???? ??? ????? ?????10~40%?? ???????Intermediate HER2+ ???α??? ??? ????? ????? ?? ??????.
 ??. ???? ???
ABP-100?? ??????? ?????????, ???1a?? ???FDA?? ?????? ???? ?????? ????? ???? IND?? ?????? ???????. ???1a?????? ?????? ?? ?????? ??????(MTD)?? ??????, ???1b?????? ??25???? ???? ???????Proof of Concept study?? ?????? ???????? ????? ???????.

?? ABP-201

??. ????
ABP-201?? ???ο? ???? ?????? ??????? VEGF?? ?????? ???????? ??? ANG-2?? ????? ??????? ??????? ????? ????????? Wet-AMD(???? ??????) ??DME(?索???? ??????) ???? ??? ??? ??? ???? ????? ??? ????? ?????? ????ð??? ?? ?????? ??????? ??????.
??. ????? ????
???? ?????????? ?? ??? ????? ????? ?? ???? ?????Abpro Corporation???κ??? ?μ??????? ??? ????????? ???, ???, ????? ??????? ??þ? ?? ?????? ???þ?? ??????CIS???? ?? ??? ??????(??48????)????.
??. ??? ????
DME?? ?索???? ??? ????? ?? ????? ???????????? ?索?? ??????? ???????? ????DME ??? ???? ?????????? ?????? ?????? ????????. ??ι? ?索?? ???? ???? ??4??????? ???????, 2035????? ??6??????? ?????? ?????? ???????.(Future Market Insights ????)
????AMD?? ?????? ???? ???? ?÷??? ????? ???? ???????, AMD ??? ???? ??15%??Wet-AMD?? ?????? ??? ?? ?????? ???????????? ??????? ?÷? ??? ??? ????? ????????. Wet-AMD?? ??????????FDA ?????? ????Lucentis??Eylea??2016?? ????????83???? ????? ??????? ???????????.
??. ???? ???
????? ??? ?????? ???, ??????? ?????? ??? ???FDA?? ?????? ???? ?????? ????? ???? IND?? ?????? ????????.

4) ???? ????

?? Abpro Corporation?? ??????

??簡 ????? ?????ABP-100 ??ABP-201?? ???????? ????Abpro Corporation?? ????? ???? ??SAB(Scientific Advisory Board)?? ??????? ??????, ?? ????? ?????? ???????.

????
???
?????
???

Chairman
IAN YAN PUI CHAN
Brown University ?????? ?л?
Harvard University MBA
US Genomics
Morgan Stanley
Bear stearns
??? ??????

CEO
EUGENE YAN HO CHAN
Harvard University ?????? ?л?
Harvard University MD
US Genomics
??? ?系???

Senior vice President
Robert Markelewicz, Jr.
Brown University ScB
Brown University MMSc
Brown University MD
Celgene
Acetylon
-

Scientific Advisory
Board
Robert Langer, PhD
?? US FDA Science Board ????
MIT ??а??? ???
Cornell University ??а??а? ?л?
Abpro Corporation
?系??? /
??? ?系???

Laurie Glimcher, MD

Dana-Faber Cancer Institute ???

Harvard University ??????? ????

?? Bristol-Myers Squibb ???? ???

Harvard University MD

Radcliffe College ?л?

-

Rita Colwell, PhD

University of Maryland ????

US FDA ????? ???????

University of Washington ????? ???

Purdue University ?????? ????

Purdue University ?????? ?л?

-

Nai-Kong Cheung, MD, PhD

ABP-100 ??????

Memorial Sloan Kettering Cancer Center

Harvard Medical School

-

Ronald Levy, MD
Stanford University ????
-

Shiv Pillai, MD, PhD
Harvard Medical School ????
-

George C. Tsokos, MD
Harvard Medical School ????
-

Abpro Corporation?? ???? ??? ?? Robert Langer ???? 400 ?? ??? ????, ???, ???????, ????? ??翡 ??? ?????? ?????????, Moderna, Acusphere, BIND Therapeutics, Enzytec, Pervasis, Transform ?? ???? ????? ??????? ?????? ??????????. ????, 1995~2002?? US FDA Science Board ???? (1999~2002 ??????)?? ???????, 1999?? Forbes?κ??? '?? ???? Biotechnology ?????? ???? ????? 25??'?? ??????? ????????.

?? ?÷??? ??? ????
 ??? ??????? ?÷????? ?????? TetraBi(????????) Format ????? ??????? ??? ?????? ???????.

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(Bivalent binding)
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X
X
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?? ?????????? ??强
ABP-100?? ???? ???? ???? ?? ???? ??? ???? ???? ????? ??????? ??? ??? ?????????? ?????? ????? ?? ????????.

??????????
ABP-100
ABP-110
ABP-130
ABP-140
ABP-150

??????
?????, ????
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????
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.

?? ??ι? ??????

??? ?? ??簡 ?????? ??????? ??? Abpro Corporation?? ????? ??ι? ???????? ??????? ??????, ??? ????? ????????? ??? ????? ??ι? ?????? ?? ??????????? ????? ?????? ????????.

??? Abpro?? AstraZeneca?? ??????? MedImmune?? ????????? Abmed?? ??????? ABP-201?? ???? ?о??? ?????????? ??????? ???? ??????. ???? ????? MSKCC(Memorial Sloan Kettering Cancer Center)?? Abpro?? ??? ???? ?? ?? ?????? ABP-100?? ???????? ??????? ??????. ????? ??ι? ???????? ???????? Abpro?? 2019?? 3?? ????? ??¡CTTQ??? 40?? ??? ????? ??????? ???? ???? ????? ?????? ??????.

2. ??????? ????????? ???????

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?? 8????2(??? ???? ??????)

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???? ????

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??12??(?????? ??????)

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?????? ????? ?????.

??14??(??ĸ???????)

?? ???? ????????? ???????? ???????????? 100???? 10 ?????????? ??ĸ????????? ?ο??? ?? ???. ???, ????? ??542????3 ??3???? ?????? ???? ???????????? 100???? 3???? ?????? ?????? ????? ??ĸ????????? ?ο??? ?? ???. ?? ??? ??ĸ????????? ?????? ??? ??????? ?? ??????? ?????????????? ?ο??? ?? ???.

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?? ???? ????????? ???????? ???????????? 100???? 15 ?????????? ??ĸ????????? ?ο??? ?? ???. ???, ????? ??542????3 ??3???? ?????? ???? ???????????? 100???? 3???? ?????? ?????? ????? ??ĸ????????? ?ο??? ?? ???. ?? ??? ??ĸ????????? ?????? ??? ??????? ?? ??????? ?????????????? ?ο??? ?? ???.

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??16????2 (?????? ???????)

?? ???? ???????????κ??? ????????? ???????? ??? ???????? ????? ???? ???????? ??????? ?????θ? ???????????? ???.

????????? ??37????6???? ???? ?????? ?????.

?? ???? 5% ??? ?????? ?????? ????(????????? ???? ???????)?? ????? ?????? ??? ?? ????? ??쿡 ?????????? ????????? ????? ????? ?? ???.

????????? ????? ??31????4????3????? ?????? ????? ??????? ???????? ????????? ??? ?????? ??????.

?? ????? ?????δ? ??? ??352????2?? ???? ????????? ??????.

??? ??352????2 ?????

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?? (????)

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?? (????? ????)

??? ??350?? ??3?? ?????? ???? ???????? ??????? ?????? ??? ?????? ????? ???? ?????? ??????.

??48??(??????????? ????)

?? ?? ?? (????)

??48??(??????????? ????)

?? ?? ?? (????? ????)

?? ??????????????? ?????? ???? ?????? ?????? ??????? ??? ???????????? 4???? 1 ????? ???? ????? ???. ???, ??? ??368????4??1??? ???? ?????? ??????? ?????? ????? ?? ????? ?? ??쿡?? ???? ?????? ?????? ??????ν? ??????????????? ?????? ?????? ?? ???.

??????? ???? ?? ????????????? ?????? ??????? ?????? ????? ???? ?????? ?????.

?? ??????????????? ?????? ???? ?????? ?????? 3???? 2 ????? ???? ???, ???????????? 3???? 1 ????? ???? ????? ???.

????????????? ????? ????? ???? ???? ?????.

?? ??3?????4???? ??????????????? ???? ??? ??????? ???? ??? ???????????? 100???? 3?? ?????? ???? ????? ???? ????(????????? ??쿡?? ?????簡 ??? ??????????????? ???? ??? ?????? ???? ???? ?????????, ??????? ??? ?? ??????????? ??????? ????? ??????? ??, ??????? ??? ?? ????????ο??? ?????? ?????? ??? ??????? ???? ??? ????? ???? ??????)?? ?? ?????? ??Ŀ? ????? ?????? ??????? ?????.

????????????? ???? ??? ????? ???? ????? ???? ???? ?????.

??48????2 (?????????? ?и??????????)

?? ??48???? ???? ??????? ??????????? ???????? ?? 1???? ??????? ????? ??? ????? ?и???? ??????????????? ??? ???? ????????? ???.

?????????? ?и?????? ???? ?????? ?????.

?? ??1??? ???? ?и??????? ??????????????? ??????? ??? ???? ??????????????? ?????? ??? ??????.

????????????? ????? ??? ???? ???? ???? ?????? ?????.

??49?? (????????? ???? ?? ????? ????)

?? ???????? ?????????? ??????? ???? ???? ????? ?????? ??????? ????? 100???? 3?? ?????? ???? ?????? ???? ????? ?? ?????? ??Ŀ? ????? ?????? ??????? ?????.

?? ??????????? ?? ????? ??????? ????? ????????? ???. ?? ??? ???????? ?????????? ???.

?? ???????? ????, ??? ???? ?????? ???????? ???? ?? ?????? ???? ??????????? ???????? ?????? ??? ?? ?????? ????? ?? ??????? ??????? ??????????? ?? ???? ???????? ????? ???.

??49?? (????????? ????? ????)

?? ??????????? ?? ????? ??????? ????? ????????? ???. ?? ??? ???????? ?????????? ???.

?? ???????? ????, ??? ???? ?????? ???????? ???? ?? ?????? ???? ??????????? ???????? ?????? ??? ?? ?????? ????? ?? ??????? ??????? ??????????? ?? ???? ???????? ????? ???.

???? ????

??51??(??????????? ?????? ???)

?? (????)

?? ??????????? ?????? ????? ????????? ?????????? ???? ???? ???(????????? ??? ??쿡?? ????????? ?????. ???? ????.)???? ??????? ???? ?????? ????? ?? ???.

?? ??2???? ????? ???????? ??簡 ??????? ?????? ???????? ?????? ?? ????? ??????????? ?????? ?????? ?? ???.

?? ??????????? ????? ????????? ?????? ?????? ?????? ?????? ?????? ??????? ???????????? ?????? ????? ?? ???.

?? ??????????? ?? ?????? ??????? ????? ????? ?????? ????翡 ????? ?????? ???? ???? ?? ???. ?? ??? ????簡 ??????? ???? ???? ????? ?? ??? ?? ?????? ?????? ????? ??? ??? ?????? ??????? ?????? ?????¸? ?????? ?? ???.

?? ??????????? ?????????? ????, ???? ?? ??????? ??? ???? ???? ?? ????????? ?????? ???? ?????? ??????.

?? ??????????? ?? 1?? ???? 5?? ??? ?????? ?????? ?????? ??????.

?? ????????? ????? ????? ?????? ??????? ?? ????.

?? ??????????? ????? ??? ????? ??????? ???????? ?????? ???? ?? ???.

??51??(??????????? ???? ??)

?? (????? ????)

?? ??????????? ????? ????????? ?????? ?????? ?????? ?????? ?????? ??????? ???????????? ?????? ????? ?? ???.

?? ??????????? ????? ??? ????? ??????? ???????? ?????? ???? ?? ???.

?? ??????????? ?? ?????? ??????? ????? ????? ?????? ????翡 ????? ?????? ???? ???? ?? ???. ?? ??? ????簡 ??????? ???? ???? ????? ?? ??? ?? ?????? ?????? ????? ??? ??? ?????? ??????? ?????? ?????¸? ?????? ?? ???.

?? ??????????? ?? 1?? ???? 4?? ??? ?????? ?????? ?????? ??????.

?? ??????????? ?????? ????? ????????? ?????????? ???? ???? ???(????????? ??? ??쿡?? ????????? ?????. ???? ????.)???? ??????? ???? ?????? ????? ?? ???.

?? ??6???? ????? ???????? ??簡 ??????? ?????? ???????? ?????? ?? ????? ??????????? ?????? ?????? ?? ???.

???? ????

??58??(??????)

?? ~ ?? (????)

?? ???????? ????????? ????? ?????.

??58??(??????)

?? ~ ?? (????)

?? ???????? ????????? ????? ?????. ???, ??55?? ??6??? ???? ?繫????? ?????? ??????? ??? ???? ????? ???????? ?????.

???? ????

?? ??? ???????

- ??? ???? ???????.

?? ????? ????

??. ??????? ?????????????????Τ??????????? ???????????????? ?? ????

????????
???????
??????
????????

????????? ??????

??? ?и????? ????

?????????? ????
?????

??????
1977.07.03
??
??
?????
????

IAN YAN PUI CHAN
1972.10.29
??
??
-
????

EUGENE YAN HO CHAN
1973.10.05
??
??
-
????

ROBERT SAMUEL LANGER
1948.08.29
??
??
-
????

??????
1967.03.03
??
??
-
????

????
1976.08.05
??
??
-
????

?????
1968.06.27
??
??
-
????

?????
1975.09.20
??
??
-
????

?? ( 8 ) ??

??. ??????? ??????????????¤?????????? ???3?? ???????

????????
???????
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?????????
???3?? ???????

??
????

??????

?????????ι???? ??????

???????????ĸ? ??????

Abpro Bio International. Inc President

??????????? ??????????? ??????

-

?????б? ?????а?

??????????????? ???

???÷????, ????????? ???

-

IAN YAN PUI CHAN

Abpro Corporation ???

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