id	label	title	paragraph	sentence
6892	0	1004724/1004724_10K_2018.htm	54	Notably, the Healthcare Reform Law resulted in expanded health care coverage to millions of previously uninsured people beginning in 2014 and has resulted in significant changes to the U.S. health care system.
6996	0	1004724/1004724_10K_2018.htm	89	In addition to the asset tests set forth above, to qualify and be subject to tax as a REIT, we would generally be required, after the utilization of any available federal net operating loss carryforwards, to distribute at least 90% of our REIT taxable income (determined without regard to the dividends paid deduction and excluding any net capital gain) each year to our shareholders.
12543	0	1006837/1006837_10K_2018.htm	108	Price fluctuations in our common stock could result from general market and economic conditions and a variety of other factors.
13779	0	1007330/1007330_10K_2018.htm	14	In addition, our credit agreements may limit our ability to take several of these actions.
18768	0	1012620/1012620_10K_2018.htm	48	The MSRS scheme, which was for a five-year period, expires in March 2020, and at present, there is no certainty as to how any successor scheme, if any, will be structured.
18950	0	1012620/1012620_10K_2018.htm	99	The Withdrawal Agreement was rejected by the U.K. Parliament and as a result, the U.K. Government is seeking to renegotiate the terms of the Withdrawal Agreement with the EU.
19072	0	1012771/1012771_10K_2018.htm	18	These values may not ultimately be realizable in a market transaction, and such values may change rapidly as market conditions change and valuation assumptions are modified.
19608	0	1013606/1013606_10K_2018.htm	33	The implementation of these rules could adversely affect the sourcing, supply and pricing of materials used in our products.
20906	0	1013880/1013880_10K_2018.htm	47	Our contracts seldom address the impacts of currency fluctuation on our costs of delivery.
23881	1	1017480/1017480_10K_2018.htm	48	Increases in transportation or shipping costs, climate change regulation and other factors may negatively impact our results of operations.
29290	0	1020214/1020214_10K_2018.htm	46	In addition, existing lots of these red blood cell compounds manufactured under cGMP may be dispositioned by regulators or ourselves as unsuitable for either commercial or clinical use which would impact our ability to produce INTERCEPT-treated red blood cells for ongoing and future clinical trials and may require changes to the manufacturing process of our red blood cell compounds or new production of the compounds, all of which would be costly and time consuming and impact our ability to perform under our contract with BARDA.
32772	0	1021635/1021635_10K_2018.htm	155	Consequently, it is possible that any of these occurrences, or a combination of them, could adversely affect Enable's financial position, results of operations and ability to make cash distributions to unitholders, including us.
34496	0	1022652/1022652_10K_2018.htm	73	Our inability to adapt to rapid technological change in our markets could impair our ability to remain competitive and adversely affect our results of operations.
35300	0	1023024/1023024_10K_2018.htm	73	The resulting accruals are significant, and as Medicaid utilizationtrends change, we may need to change our estimates accordingly.
46179	0	1034670/1034670_10K_2018.htm	67	Some of our customers are (or may be) owned by a governmental entity, receive various forms of governmental aid or support or are subject to governmental influence in other forms, which may impact us as a supplier to these customers.
49464	1	1035443/1035443_10K_2018.htm	253	For example, most of our properties are located along the east and west coasts of the U.S. To the extent that climate change impacts changes in weather patterns, our markets could experience increases in storm intensity and rising sea levels.
49732	0	1035976/1035976_10K_2018.htm	25	FNCB may also be subject to potentially adverse regulatory consequences.
51492	0	103730/103730_10K_2018.htm	80	• changes in GAAP or interpretations of GAAP by governmental agencies and self-regulatory groups;.
54798	0	1038357/1038357_10K_2018.htm	112	If any of the Company's swaps do not qualify for the commercial end-user exception, the posting of collateral could reduce its liquidity and cash available for capital expenditures and could reduce its ability to manage commodity price volatility and the volatility in its cash flows.
56936	0	1040161/1040161_10K_2018.htm	58	A change in these principles or interpretations could have a significant effect on our reported financial results and could materially and adversely affect the transactions completed before the announcement of a change.
65038	0	1045450/1045450_10K_2018.htm	137	Likewise, our Board of Trustees is authorized to cause us to issue preferred shares in one or more series, the holders of which would be entitled to dividends and voting and other rights as our Board of Trustees determines, and which could be senior to or convertible into our common shares.
69979	0	1048286/1048286_10K_2018.htm	8	Weak economic conditions in one or more parts of the world, changes in oil prices and currency values, disruptions in national, regional, or global economies generally and the travel business in particular that might result from changing governmental policies in areas such as trade, travel, immigration, healthcare, and related issues, political instability in some areas, and the uncertainty over how long any of these conditions could continue, could have a negative impact on the lodging industry.
72685	0	1050441/1050441_10K_2018.htm	7	As it is in the short seller’sinterest for the price of the stock to decline, some short sellers publish, or arrange for the publication of, opinions or characterizationsregarding the relevant issuer, its business practices and prospects and similar matters calculated to or which may create negativemarket momentum, which may permit them to obtain profits for themselves as a result of selling the stock short.
73022	0	1050446/1050446_10K_2018.htm	11	• any major change in our Board of Directors, management, or governing documents;.
79013	1	1054905/1054905_10K_2018.htm	69	We may be exposed to certain regulatory and financial risks related to climate change
81598	0	1056386/1056386_10K_2018.htm	18	• avoid labor issues impacting our suppliers, such as a strike; and.
92796	0	1065280/1065280_10K_2018.htm	40	Given this, along with the fact that we cannot easily switch our AWS operations to another cloud provider, any disruption of or interference with our use of AWS would impact our operations and our business would be adversely impacted.
102963	1	1070423/1070423_10K_2018.htm	14	Supply and demand for crude oil and other hydrocarbon products we handle is dependent upon a variety of factors, including price, the impact of future economic conditions, fuel conservation measures, alternative fuel adoption, governmental regulation, including climate change regulations, and technological advances in fuel economy and energy generation devices.
103145	0	1070423/1070423_10K_2018.htm	65	We do not have cost-of-service rates that would be impacted by this policy change; our FERC regulated tariffs are either grandfathered or based on negotiated rates.
106985	0	107263/107263_10K_2018.htm	46	An event such as those described above could have a material adverse effect on our financial condition and results of operations, particularly if the event is not fully covered by insurance.
115905	1	1084384/1084384_10K_2018.htm	3	The current economic climate, especiallyin Europe, may have an adverse effect in the markets in which we operate.
117745	0	108516/108516_10K_2018.htm	40	If there is a change in ownership, a change of control, a change in management or management philosophy, a change in business strategy or another event with respect to a member of a joint venture that adversely impacts the relationship between the joint venture members, it could adversely impact that joint venture.
119740	1	108772/108772_10K_2018.htm	61	Other potentially relevant initiatives throughout the world include proposals for more extensive chemical registration requirements and/or possible bans on the use of certain chemicals, various efforts to limit energy use in products and other environmentally related-programs impacting products and operations, such as those associated with climate change accords, agreements and regulations.
120153	0	1088856/1088856_10K_2018.htm	117	Provisions in our charter and bylaws may delay or prevent an acquisition of us or a change in our management.
122126	1	1090727/1090727_10K_2018.htm	16	For example, in 2009 the European Commission approved the extension to the airline industry of the European Union Emissions Trading Scheme (“ETS”) for GHG emissions.
122136	1	1090727/1090727_10K_2018.htm	19	We may face additional regulations regarding GHG emissions internationally and in the United States.
126697	1	1094285/1094285_10K_2018.htm	12	• climate change regulation that provide incentives to conserve energy or use alternative energy sources.
126774	0	1094285/1094285_10K_2018.htm	28	If the fair market value is less than the carrying value, including goodwill, we could be required to record an impairment charge.
128067	0	1094810/1094810_10K_2018.htm	48	Banks, securities firms and insurance companies can merge under the umbrella of a bank holding company, which can offer virtually any type of financial service, including banking, securities underwriting, insurance (both agency and underwriting) and merchant banking.
132286	0	1096343/1096343_10K_2018.htm	482	Change in fair value of equity securities held at the end of the period
134512	1	1099219/1099219_10K_2018.htm	115	In addition, climate change regulation may affect the prospects of companies and other entities whose securities we hold or our willingness to continue to hold their securities.
134803	0	1099590/1099590_10K_2018.htm	36	Content owners and other intellectual property rights owners have been active in asserting their purported rights against online companies.
136562	0	1101215/1101215_10K_2018.htm	99	These include our Board’s authority to issue shares of preferred stock without further stockholder approval.
145549	0	1110805/1110805_10K_2018.htm	89	If the FERC’s ratemaking methodologies change, such change or new methodologies could result in rates that generate lower revenues and cash flow and could adversely affect our ability to make distributions to our unitholders and to meet our debt service requirements.
147420	0	1113148/1113148_10K_2018.htm	227	A stockholder lawsuit could also divert the time and attention of our management.
174694	0	1137883/1137883_10K_2018.htm	53	We face competition in our effortsto develop cell therapies for ALS and other neurodegenerative diseases.
190992	0	1160958/1160958_10K_2018.htm	119	While we are not aware of any other current or proposed export or import regulations which would materially restrict our ability to sell our products in other countries, any change in export or import regulations or related legislation, shift in approach to the enforcement or scope of existing regulations, or change in the countries, persons or technologies targeted by these regulations, could result in decreased use of our products by, or in our decreased ability to export or sell our products to, existing or potential customers with international operations.
192797	0	1163739/1163739_10K_2018.htm	32	We also have various financial commitments, such as leases, contracts and purchase commitments.
193375	1	1164727/1164727_10K_2018.htm	107	Conference of the Parties of the United Nations Framework Convention on Climate Change (“UNFCC”) held in Paris in 2015, the Paris Agreement was adopted which was intended to govern emission reductions beyond 2020.
193378	1	1164727/1164727_10K_2018.htm	107	Industrialized nations (e.g., Australia) are likely to implement national emission reduction targets that require an investment shift towards low carbon technologies and systems, shifting away from coal and diesel power generation.
194602	0	1166388/1166388_10K_2018.htm	83	In addition, because our indebtedness under our 2017 Credit Agreement bears interest at a variable rate, we are exposed to risk from fluctuations in interest rates.
201633	1	1172358/1172358_10K_2018.htm	55	These regulations are designed to reduce volatile organic compound (“VOC”) emissions from hydraulically fractured wells and other equipment.
211321	0	1178711/1178711_10K_2018.htm	196	A default under the indenture or the fundamental change itself could also lead to a default under the Hercules Loan Agreement, as amended, or agreements governing our future indebtedness.
221913	0	1217234/1217234_10K_2018.htm	111	We completed its analysis of the impacts of the 2017 Tax Act in the fourth quarter of 2018 with no net change to its provisional estimates due to the valuation allowance.
222139	0	1217234/1217234_10K_2018.htm	171	Further, our combination with Allenex will also change how these provisions could impact our business.
225684	1	1223389/1223389_10K_2018.htm	83	Because of fears of climate change and adverse effects of drilling explosions and oil spills in the Gulf of Mexico, legislation has been considered, and governmental regulations and orders have been issued, which, combined with the local economic and employment conditions caused by both, could materially adversely impact the oil and gas industries and the economic health of areas in which a significant number of our stores are located.
227050	0	1226616/1226616_10K_2018.htm	104	• in certain circumstances, including with respect to the commercialization of our product candidates in Europe, increased dependence on the commercialization efforts of our distributors or strategic partners;.
240084	0	1262039/1262039_10K_2018.htm	69	Non-compliance with the GDPR could result in significant penalties, including data protection audits and heavy fines.
241067	1	1262823/1262823_10K_2018.htm	38	The United States signed the Paris Agreement in April 2016, and the Paris Agreement went into effect in November 2016.
241266	0	1262823/1262823_10K_2018.htm	90	"If the Internal Revenue Service (""IRS"") were to treat Westlake Partners as a corporation for federal income tax purposes, or if Westlake Partners become subject to entity-level taxation for state tax purposes, its cash available for distribution would be substantially reduced, which would also likely cause a substantial reduction in the value of its common units that we hold."
251053	0	1273685/1273685_10K_2018.htm	47	A change in our investment strategy, financing strategy or hedging strategy may increase our exposure to real estate values, interest rates, prepayment rates, credit risk and other factors and there can be no assurance that we will be able to effectively identify, manage, monitor or mitigate these risks.
255686	0	1276187/1276187_10K_2018.htm	112	The prices for natural gas, NGLs, crude oil and refined petroleum products reflect market demand that fluctuates with changes in global and United States economic conditions and other factors, including:.
256823	0	1276520/1276520_10K_2018.htm	130	In addition, we cannot be certain that affordable alternativefinancing would be available.
264802	1	1283140/1283140_10K_2018.htm	57	Requiring reductions in greenhouse gas emissions could cause us to incur substantial costs to (i) operate and maintain our facilities, (ii) install new emission controls at our facilities and (iii) administer and manage any greenhouse gas emissions programs, including the acquisition or maintenance of emission credits or allowances or the payment of carbon taxes.
266165	1	1285785/1285785_10K_2018.htm	110	Our Saskatchewan Potash facilities will be subject to the Saskatchewan climate change plan regarding emissions at our facilities; however, indirect costs from the carbon tax associated with electricity, natural gas consumption, and transportation may be passed through to Mosaic.
269000	0	1280784/1280784_10K_2018.htm	29	A number of BBA member banks entered into settlements with their regulators and law enforcement agencies with respect to alleged manipulation of LIBOR, and investigations by regulators and governmental authorities in various jurisdictions are ongoing.
280954	0	1294133/1294133_10K_2018.htm	107	Additionally, significant changes to U.S. GAAP resulting from the FASB’s and IASB’s efforts may require that we change how we process, analyze and report financial information and that we change financial reporting controls.
283197	0	1297184/1297184_10K_2018.htm	125	Any such changes could have a material adverse effect on our business, financial position and results of operations and could cause the market value of our common stock to decline.
293818	0	1305323/1305323_10K_2018.htm	100	We may be required to reduce our tuition or increase marketing spending in order to attract or retain students or to pursue new market opportunities.
294243	0	1305773/1305773_10K_2018.htm	54	ACOs use these payments to provide care for their patients.
296184	1	1309082/1309082_10K_2018.htm	86	Methane, a primary component of natural gas, and carbon dioxide, a by-product of the burning of oil, naturalgas and refined petroleum products, are considered greenhouse gases.
297434	0	1311241/1311241_10K_2018.htm	111	If any of the analysts who cover us change their recommendations regarding our stock adversely, or provide more favorable relative recommendations about our competitors, our stock price would likely decline.
302618	0	1321646/1321646_10K_2018.htm	17	Conditions in the global economy and capital markets which may have an adverse effect on our results of operations, financial condition, and cash flow .
302927	0	1321646/1321646_10K_2018.htm	116	Provisions of our charter and bylaws may have the effect of delaying, deferring or preventing a change in control of our company.
303394	0	1321732/1321732_10K_2018.htm	120	We are required to register with the FDA as a device manufacturer and as a result, we are subject to periodic inspection by the FDA for compliance with the FDA’s Quality System Regulation (“QSR”) requirements, which requires manufacturers of medical devices to adhere to certain requirements, including testing, quality control and documentation procedures.
304676	0	1322439/1322439_10K_2018.htm	124	Accordingly, no assurance can be given that the IRS or a court of law will accept our position, and there is a risk that the IRS or a court of law could determine that we are a PFIC.
307964	1	1324404/1324404_10K_2018.htm	85	A facility whose carbon emissions exceed this benchmark will be required to offset excess emissions by obtaining and retiring surplus emission credits; obtaining qualifying emission offsets; or paying a fee of $20 per ton of excess CO 2 e for calendar year 2019, which fee will rise by $10 per ton each year through 2022.
308984	0	1325670/1325670_10K_2018.htm	113	In recent years, we have incurred significant expense towards improving the reliability of our systems and their security from attack.
309438	0	1325702/1325702_10K_2018.htm	127	Due to the inherent uncertainty of the litigation process, the resolution of any particular legal claim or proceeding could have a material effect on our business, financial condition,results of operations or cash flows.
325926	0	1337553/1337553_10K_2018.htm	59	In our Phase 3 registration trials, some patients also experienced conjunctival hemorrhages, or petechiae, corneal verticillata, blurry vision, and decreased visual acuity as adverse events.
327177	0	1337619/1337619_10K_2018.htm	129	Bribery Act, import and export control laws, tariffs, trade barriers, economic sanctions and other regulatory or contractual limitations on our ability to sell our solutions in certain foreign markets, and the risks and costs of compliance;.
338129	0	1348036/1348036_10K_2018.htm	102	We may not be able to determine in the future that our internal controls over financial reporting are effective, and we may not receive an auditor attestation regarding our internal controls in the foreseeable future.
341776	0	1351636/1351636_10K_2018.htm	52	• limiting our flexibili ty to plan for and adjust to changing business and market conditions and increasing our vulnerability;.
348155	0	1358403/1358403_10K_2018.htm	144	The EMA's, FDA’s and other regulatory authorities’ policies may change, and additional government regulations may be enacted that could prevent, limit or delay regulatory approval of our product candidates.
352959	0	1262039/1262039_10K_2018.htm	91	Any change in export or import regulations, economic sanctions or related legislation, shift in the enforcement or scope of existing regulations, or change in the countries, governments, persons or technologies targeted by such regulations, could result in decreased use of our products by, or in our decreased ability to export or sell our products to, existing or potential customers with international operations.
362690	0	1367083/1367083_10K_2018.htm	25	While we havetaken precautions against flooding, we cannot assure that heavy rain will not cause significant disruption to our business.
367467	0	1369568/1369568_10K_2018.htm	41	We cannot be sure that we will successfully manufacture any product, either independently or under manufacturing arrangements, if any, with third party manufacturers.
373256	0	1372807/1372807_10K_2018.htm	155	Our distributions have over the last several years included a significant return of capital component.
374975	0	1374310/1374310_10K_2018.htm	119	Legislation may be proposed, both domestically and internationally, that could add a transaction tax on our products or change the way that our market participants are taxed on the products they trade on our markets.
390927	0	1385613/1385613_10K_2018.htm	93	Registered investment companies are subject to extensive, restrictive and potentially adverse regulation relating to, among other things, operating methods, management, capital structure, leverage, dividends and transactions with affiliates.
395586	1	1389170/1389170_10K_2018.htm	120	In the United States, no comprehensive climate change legislation has been implemented at the federal level, to date.
404153	0	1394156/1394156_10K_2018.htm	77	We review goodwill for impairment annually, or whenever circumstances change in a way which could indicate that impairment may have occurred.
412901	1	1401680/1401680_10K_2018.htm	13	These laws and regulations are complex and change frequently, at times due to differing economic conditions and changes in political climate, with new laws and regulations proposed frequently and existing laws and regulations subject to different and conflicting interpretations.
419212	0	1403853/1403853_10K_2018.htm	122	On January 9, 2014, the EPA issued a revised CWA permit requiring oil and natural gas companies using hydraulic fracturing off the coast of California to disclose the chemicals they discharge into the ocean.
425761	0	1408198/1408198_10K_2018.htm	52	It is possible that laws or regulations could cause us to restrict or change the way we license and price our products or could impose additional costs on us.
429725	0	1410384/1410384_10K_2018.htm	126	• reduced or varied protection for intellectual property rights in some countries; and.
440805	0	1419041/1419041_10K_2018.htm	87	The Loan Agreement includes affirmative and negative covenants applicable to us and any subsidiaries we create in the future.
443463	0	1420302/1420302_10K_2018.htm	120	If securities or industry analysts who cover us, our business or our market publish a negative report or change their recommendations regarding our stock adversely, our stock price and trading volume could decline.
453272	0	1425205/1425205_10K_2018.htm	66	Any of these challengescould delay completion of clinical trials, require bridging clinical trials or the repetition of one or more clinical trials, increaseclinical trial costs, delay approval of our product candidate, impair commercialization efforts, increase our cost of goods, andhave an adverse effect on our business, financial condition, results of operations and growth prospects.
477642	0	1441816/1441816_10K_2018.htm	140	If we are unable to assert that our internal control over financial reporting is effective, or if our independent registered public accounting firm is unable to express an opinion on the effectiveness of our internal control over financial reporting, we could lose investor confidence in the accuracy and completeness of our financial reports, which could have an adverse effect on our business and results of operations and could cause a decline in the price of our Class A common stock, and we may be subject to investigation or sanctions by the SEC.
479385	0	1443646/1443646_10K_2018.htm	35	Any adjustment as a result of a change in estimate is recognized as events become known.
487453	0	1449792/1449792_10K_2018.htm	6	• a change in the demand or production of our products caused by severe weather conditions;.
488656	0	1453593/1453593_10K_2018.htm	33	We are highly reliant on our Belgrade, Montana facilities.Any natural or man-made event that impacts our ability to utilize these facilities could have a significant impact on our operatingresults, reputation and ability to continue operations.
498952	0	1463172/1463172_10K_2018.htm	136	An adverse change in market conditions, particularly a change resulting in a significant decrease in our share price, or if such change has the effect of changing one of our critical assumptions or estimates, could result in a change to the estimation of fair value that could result in an impairment charge to our goodwill or intangible assets.
502924	0	1465128/1465128_10K_2018.htm	59	In order for us to borrow funds under a repurchase agreement, our lender must have the right to review the potential assets for which we are seeking financing and approve such assets in its sole discretion.
512431	0	1469367/1469367_10K_2018.htm	47	These incentives have had a significant impact on the development of solar energy but they could change at any time, especially in light of the recent change in administration, as further described below.
513767	0	1469443/1469443_10K_2018.htm	147	Any unanticipated change in revenues or operating results is likely to cause our stock price to fluctuate since such changes reflect new information available to investors and analysts.
519627	0	1476150/1476150_10K_2018.htm	8	If our revenue does not keep pace with these potential acquisition costs, we may not be able to maintain our current or expected earnings as we absorb these additional expenses.
523932	0	1479094/1479094_10K_2018.htm	119	If the credit environment is constrained at the time the balloon payment is due, we may not be able to refinance the existing financing on acceptable terms and may be forced to choose from a number of unfavorable options.
527016	0	1481832/1481832_10K_2018.htm	87	If any of the foregoing events occur, the returns on our investments, our ability to make distributions to stockholders and the value of our stockholders' investment may suffer.
533364	0	1487712/1487712_10K_2018.htm	66	Although we anticipate that the financial obligations relating to these liens are the responsibility of our lessees, if they fail to fulfill such obligations, the liens may attach to our aircraft and ultimately become our responsibility.
547638	0	1234006/1234006_10K_2018.htm	115	These requirements could have the effect of inhibiting a change in control even if a change in control were in our stockholders’ interest.
559382	0	1501989/1501989_10K_2018.htm	199	• actions taken by regulatory agencies with respect to our products, clinical studies, manufacturing process or sales and marketing terms;.
562011	0	1505155/1505155_10K_2018.htm	14	• record goodwill and non-amortizable intangible assets that are subject to impairment testing and potential impairment charges;.
562666	1	1505413/1505413_10K_2018.htm	59	In 2009, the EPA published its findings that emissions of carbon dioxide, methane and other GHGs present an endangerment to publichealth and the environment because emissions of such gases are, according to the EPA, contributing to the warming of the earth's atmosphere and other climate changes.
562677	1	1505413/1505413_10K_2018.htm	60	"Inaddition, in November 2016, the U.S. Department of the Interior Bureau of Land Management, or ""BLM,"" issued final rules to reduce methane emissions from venting, flaring, and leaksduring oil and gas operations on federal and tribal lands that are substantially similar to the EPA's Methane Rule."
565980	0	1507079/1507079_10K_2018.htm	164	Our Board has the authority to cause us to issue, without any further vote or action by our stockholders, shares of preferred stock, par value $0.001 per share, in one or more series, to designate the number of shares constituting any series and to fix the rights, preferences, privileges and restrictions thereof, including dividend rights, voting rights, rights and terms of redemption, redemption price or prices and liquidation preferences of such series.
566059	0	1507957/1507957_10K_2018.htm	23	Accordingly, there are no assurances our change in strategicfocus will be successful, which may have an adverse effect on our results of operations and financial condition.
573910	0	1512673/1512673_10K_2018.htm	12	If we are unable to generate adequate revenue growth and manage our expenses, we may continue to incur significant losses and may not achieve or maintain profitability.
578704	0	1514281/1514281_10K_2018.htm	179	The management agreement provides that it may be terminated annually by us without cause upon the affirmative vote of at least two-thirds of our independent directors or by a vote of the holders of at least two-thirds of our outstanding common stock, in each case based upon (i) our Manager’s unsatisfactory performance that is materially detrimental to us or (ii) our determination that the management fees payable to our Manager are not fair, subject to our Manager’s right to prevent termination based on unfair fees by accepting a reduction of management fees agreed to by at least two-thirds of our independent directors.
582861	0	1517022/1517022_10K_2018.htm	193	Further, we may not pursue or obtain patent protection in all major markets.
584004	1	1517175/1517175_10K_2018.htm	92	Increased regulation regarding GHG emissions, especially diesel engine emissions, could impose substantial costs upon us.
586997	0	1520048/1520048_10K_2018.htm	74	In December 2016 the EPA issued a final report on the potential impacts of hydraulic fracturing on drinking water resources.
590809	1	1522727/1522727_10K_2018.htm	77	Specifically, the EPA’s rule package included New Source Performance Standards to address emissions of sulfur dioxide and volatile organic compounds (“VOCs”) and a separate set of emissions standards to address hazardous air pollutants frequently associated with oil and natural gas production and processing activities.
601761	1	1527709/1527709_10K_2018.htm	79	In May 2016, the EPA issued new regulations that set methane and VOC emission standards for certain oil and natural gas facilities.
601777	1	1527709/1527709_10K_2018.htm	84	As an example, until December 31, 2014, owners and operators of hydraulically fractured gas wells could either flare their emissions or use emissions reduction technology called “green completions” technologies already deployed at wells.
602160	0	1528849/1528849_10K_2018.htm	28	Customer response depends substantially on product assortment, product availability and creative presentation, the selection of customers to whom the catalogs are mailed, changes in mailing strategies, page size, page count, frequency and timing of delivery of catalogs, as well as the general retail sales environment and current domestic and global economic conditions.
613442	0	1537028/1537028_10K_2018.htm	35	The EPA conducted a study of the potential impacts of hydraulic fracturing on drinking water and issued a final report in December 2016.
618011	0	1539029/1539029_10K_2018.htm	213	These registered shares will be available for sale in the public market subject to vesting arrangements and exercise of options, the lock-up agreements described above and, in the case of our affiliates, the restrictions of Rule 144.
620835	0	1540755/1540755_10K_2018.htm	191	We currently intend to retain any future earnings to finance the operation andexpansion of our business, and we do not expect to declare or pay any dividends in the foreseeable future.
646022	0	1377121/1377121_10K_2018.htm	262	We are an “emerging growth company” and as a result of the reduced disclosure and governance requirements applicable to emerging growth companies, our common stock may be less attractive to investors.
659638	0	1567345/1567345_10K_2018.htm	81	In March 2018 Congress authorized an additional $1 billion to be used for reimbursements related to repacking and directed that a portion of the additional funds be usedto reimburse low power television stations, television translator stations and FM stations that are required to modify their facilities on a temporary or permanent basis to accommodate changes made bytelevision stations being repacked as well as for consumer education efforts.
671507	1	1575051/1575051_10K_2018.htm	114	Although the U.S. Congress has not adopted such legislation at this time, many states continue to pursue regulations to reduce GHG emissions.
671945	0	1575189/1575189_10K_2018.htm	36	In order for us to succeed, our systems and infrastructures must perform well on a consistent basis.
676054	1	1576940/1576940_10K_2018.htm	48	In addition, there is a variety of new legislation being enacted, or considered for enactment, at the federal, state and local level relating to energy and climate change, and as climate change concerns continue to grow, legislation and regulations of this nature are expected to continue.
676126	0	1561680/1561680_10K_2018.htm	72	A major health and safety incident relating to our business could be costly in terms of potential liabilities and reputational damage.
682356	0	1579214/1579214_10K_2018.htm	89	• our ability to complete and integrate new acquisitions;.
685905	0	1580345/1580345_10K_2018.htm	82	The effect of this change and any further rules or regulations are and could be complex and far-reaching, and the change and any future laws or regulations or changes thereto could negatively impact our operations, cash flows or financial condition, impose additional costs on us, intensify the regulatory supervision of us or otherwise adversely affect our business, financial condition and results of operations.
694241	0	1585583/1585583_10K_2018.htm	161	If one or more of the analysts who cover us downgrade our common stock or change their opinion on our common stock, our stock price would likely decline.
698284	0	1587987/1587987_10K_2018.htm	36	To the extent we borrow money to finance investments, our net investment income will depend, in part, upon the difference between the rate at which we borrow funds and the rate at which we invest those funds.
701000	0	1590584/1590584_10K_2018.htm	87	We may not be able to reduce our indebtedness to comply with these covenants.
703868	0	1590955/1590955_10K_2018.htm	96	Projections are also based upon specific assumptions with respect to future business decisions, some of which will change.
705784	0	1591763/1591763_10K_2018.htm	10	We depend on a small number of customers for a significant portion of our gathering and processing revenues and our transportation and storage revenues.
707817	0	1592057/1592057_10K_2018.htm	4	• the effects of Brexit on our and our customers’ businesses; and.
713503	1	1594466/1594466_10K_2018.htm	107	Facilities required to obtain PSD permits for their GHG emissions also will be required to meet “best available control technology” standards for these emissions.
715116	0	1596532/1596532_10K_2018.htm	104	• greater risk of changes in diplomatic and trade relationships, including new tariffs, trade protection measures, import or export licensing requirements, trade embargoes and other trade barriers;.
722274	0	1599617/1599617_10K_2018.htm	11	Oil and natural gas prices have been and are expected to remain volatile.
725713	1	1539838/1539838_10K_2018.htm	114	As our operations also emit greenhouse gases directly, current and future laws or regulations limiting such emissions could increase our own costs.
730747	1	1262823/1262823_10K_2018.htm	44	Various jurisdictions have considered or adopted laws and regulations on GHG emissions, with the general aim of reducing such emissions.
743724	0	1610092/1610092_10K_2018.htm	17	Further, the timing of assessments, changes in the manner in which DIR fees are assessed and methodology in computing DIR fees may materially impact our ability to provide accurate financial guidance to investors and analysts, and may result in a future change in the estimated DIR fees we have recognized.
744429	0	1610250/1610250_10K_2018.htm	43	If we encounter any disruptions to our operations at these locations or if they were to shut down for any reason, including due to fire, tornado or other natural disaster, then we may be prevented from effectively operating our stores and our e-commerce businesses.
745884	0	1610618/1610618_10K_2018.htm	131	We are subject to laws and regulations governing data privacy and the protection of personal information.
748026	0	1611983/1611983_10K_2018.htm	29	Charter’s services may not allow it to compete effectively.
759532	0	1619739/1619739_10K_2018.htm	21	We do not maintain insurance coverage against all potential losses and could suffer losses for uninsurable or uninsured risks or in amounts in excess of existing insurance coverage.
765919	0	1621443/1621443_10K_2018.htm	177	• delaying, deferring or preventing a change in control of our company;.
780590	0	1629137/1629137_10K_2018.htm	9	In addition, we may seek additional capital due to favorable marketconditions or strategic considerations even if we believe we have sufficient funds for our current or future operating plans.
784253	0	1631574/1631574_10K_2018.htm	69	Key participants in pharmaceutical marketplaces, such as physicians, third-party payors and consumers, may not adopt a product intended to improve therapeutic results that is based on the technology employed by oligonucleotides.
784700	0	1631574/1631574_10K_2018.htm	165	Some of our cases have been filed in, for example, Argentina, Australia, Brazil, Canada, Chile, China, Europe, Hong Kong, Indonesia, Israel, India, Japan, Malaysia, New Zealand, South Korea, Mexico, Russia, Singapore, South Africa, Taiwan, United Arab Emirates, and Venezuela.
786684	1	1633651/1633651_10K_2018.htm	157	In May 2016, the EPA issued final rules that update new source performance standard requirements and that will impose more stringent controls on methane and volatile organic compounds emissions from oil and gas development and production operations, including hydraulic fracturing and other well completion activity.
787015	0	1633651/1633651_10K_2018.htm	273	Our current tax treatment may change, which could affect the value of our Class A shares or reduce our cash available for dividends.
792417	0	1636050/1636050_10K_2018.htm	176	Our in-licensed and owned patent portfolio alone may not provide us with sufficient rights to exclude others from commercializing products similar or identical to ours.
798107	0	1590976/1590976_10K_2018.htm	49	We compete with a variety of other activities for consumers’ scarce leisure time.
800885	0	1274792/1274792_10K_2018.htm	188	In the United States and some foreign jurisdictions, there have been and continue to be a number of legislative and regulatory changes and proposed changes regarding the healthcare system that could, among other things, prevent or delay marketing approval of our product candidates, restrict or regulate post-approval activities and affect our ability, or the ability of any future collaborators, to profitably sell any products for which we, or they, obtain marketing approval.
801131	0	1070081/1070081_10K_2018.htm	245	Current and future legislation may significantly change the approval requirements in ways that could involve additional costs and cause delays in obtaining approvals.
820099	0	1651094/1651094_10K_2018.htm	98	In the states in which we originate Rise under a state-license, the rates and terms vary based on specific state laws.
821240	0	1651235/1651235_10K_2018.htm	181	These requirements have increased and will continue to increase our legal, accounting and financial compliance costs and have made and will continue to make some activities more time consuming and costly.
822980	0	1651561/1651561_10K_2018.htm	154	These laws and regulations, including their interpretation by governmental agencies, are subject to frequent change.
824169	1	1652044/1652044_10K_2018.htm	79	We may experience supply shortages and price increases driven by raw material availability, manufacturing capacity, labor shortages, industry allocations, natural disasters, the effects of climate change (such as sea level rise, drought, flooding, wildfires, and increased storm severity), and significant changes in the financial or business condition of our suppliers.
832276	0	1485003/1485003_10K_2018.htm	99	Current and future legislation may significantly change the approval requirements in ways that could involve additional costs and cause delays in obtaining approvals.
835782	0	1657788/1657788_10K_2018.htm	51	Furthermore, many factors could impair our access to future acquisitions, including a change in control of any of our Sponsors and the Contributing Parties.
842403	1	1660734/1660734_10K_2018.htm	33	As of January 1, 2020, the International Maritime Organization regulation referred to as IMO 2020 will require all vessels to burn fuel with a sulfur content of no more than 0.5% unless fitted with an exhaust gas emissions cleaner (scrubber) capable of reducing sulfur emissions to 0.5% or less.
842895	0	1661053/1661053_10K_2018.htm	10	We will need to seek additional funds in the future through equity or debt financings, or strategicalliances with third parties, either alone or in combination with equity financings to complete our product development initiatives.These financings could result in substantial dilution to the holders of our common stock, or require contractual or other restrictionson our operations or on alternatives that may be available to us.
844373	0	1661920/1661920_10K_2018.htm	51	Unless production is established on the undeveloped acreage covered by our leases, such leases will expire.
849427	0	1666071/1666071_10K_2018.htm	172	A change in these principles or interpretations could have a significant effect on our reported financial results, and could affect the reporting of transactions completed before the announcement of a change.
851662	0	1668105/1668105_10K_2018.htm	47	Additionally, the success of new product introductions depends on a number of factors including, but not limited to, timely and successful product development, market acceptance, our ability to manage the risks associated with new product releases, our ability to successfully plan and execute on a sales strategy for our new products, the availability of software components for new products, the effective management of development and other spending in connection with anticipated demand for new products, the availability of newly developed products and the risk that new products may have bugs, errors or other defects or deficiencies in the early stages of introduction.
855171	0	1669162/1669162_10K_2018.htm	105	We may change our underwriting guidelines or our strategy without stockholder approval.
859515	0	1671933/1671933_10K_2018.htm	70	Our privacy policies and business operations may have to change to adapt to any such changes in our business environment .
868901	0	1677703/1677703_10K_2018.htm	114	Any such indemnification obligation could materially adversely affect our results of operations and financial condition.
874851	1	1539838/1539838_10K_2018.htm	59	The resulting Paris Agreement calls for the parties to undertake “ambitious efforts” to limit the average global temperature, and to conserve and enhance sinks and reservoirs of greenhouse gases.
875773	0	1681087/1681087_10K_2018.htm	2	We expect to incur net losses for the foreseeable future and may never achieve or maintainprofitability.
876567	0	1681087/1681087_10K_2018.htm	192	If we fail to comply with environmental, health and safety laws and regulations, wecould become subject to fines or penalties or incur costs that could have a material adverse effect on the success of our business.
892224	0	1690769/1690769_10K_2018.htm	249	If FERC were to consider the status of an individual facility and the character of a crude oil or NGL shipment, and determine that the shipment is in interstate commerce, the rates for, and terms and conditions of, transportation services provided by such facility would be subject to regulation by FERC under the ICA.
894576	0	1692412/1692412_10K_2018.htm	194	Withholding of 25% of gross sale proceeds is required of the buyer only if the latter is a Mexican resident.
895579	1	1692787/1692787_10K_2018.htm	113	The Paris Agreement was signed by the United States in April 2016 and entered into force in November 2016; however, the GHG emission reductions called for by the Paris Agreement are not binding.
903278	0	1049782/1049782_10K_2018.htm	71	If the models used to mitigate these risks are inadequate, we may incur losses.
903569	1	1699039/1699039_10K_2018.htm	75	In addition, in 2015, the U.S. participated in the United Nations Conference on Climate Change, which led to the creation of the Paris Agreement.
907910	0	1701732/1701732_10K_2018.htm	120	• modification of existing or implementation of new tariffs;.
908265	0	1702750/1702750_10K_2018.htm	19	Therefore, any change in general market interest rates, including changes in federal fiscal and monetary policies can have a significant effect on our net interest income and results of operations.
912957	0	1704715/1704715_10K_2018.htm	184	As a result of any of these actions, the restrictions and covenants that apply to us may become more restrictive or otherwise change.
918203	0	1404281/1404281_10K_2018.htm	259	• delay, defer or prevent a change in control;.
919653	0	1637207/1637207_10K_2018.htm	150	These provisions may limit a stockholder’s ability to bring a claim in a judicial forum that it finds favorable for disputes with us or our directors, officers or other employees, which may discourage such lawsuits against us and our directors, officers and employees.
926751	0	1710155/1710155_10K_2018.htm	5	• participate in managed care arrangements for new stores;.
929986	0	1711291/1711291_10K_2018.htm	36	We may be required to recognize impairment of goodwill based on future events or circumstances which could include a significant change in the business climate, a change in strategic direction, legal factors, operating performance indicators, a change in the competitive environment, the sale or disposition of a significant portion of a reporting unit or future economic factors such as unfavorable changes in the estimated future discounted cash flows of our reporting units.
932066	0	1709682/1709682_10K_2018.htm	161	Provisions in our amended and restatedmemorandum and articles of association may inhibit a takeover of us, which could limit the price investors might be willing topay in the future for our Class A ordinary shares and could entrench management.
932410	0	1712923/1712923_10K_2018.htm	92	Industries change rapidly, and we make no assurance that we will be able to accurately forecast demand (or the lack thereof) for our solution or that those industries will grow.
932490	0	1614178/1614178_10K_2018.htm	118	A change in these principles or interpretations could have a significant effect on our reported financial results and could affect the reporting of transactions completed before the announcement of a change.
934122	0	1716621/1716621_10K_2018.htm	140	Reimbursement rates are unpredictable, and we cannot project how our business may be affected by future legislative and regulatory developments.
936506	1	1717547/1717547_10K_2018.htm	145	If we, or other companies with which we do business, particularly utilities that provide our facilities with electricity, become subject to laws or regulations related to climate change, it could have a material adverse effect on us.
941445	0	1720580/1720580_10K_2018.htm	116	Regulatory authorities have substantial discretion in the approval process and may refuse to accept any application or may decide that our data are insufficient for approval and require additional preclinical, clinical or other studies.
942798	0	1718405/1718405_10K_2018.htm	165	The warrant agreementprovides that the terms of the warrants may be amended without the consent of any holder to cure any ambiguity or correct any defectiveprovision, but requires the approval by the holders of at least 65% of the then outstanding public warrants to make any changethat adversely affects the interests of the registered holders of public warrants.
946701	1	1722287/1722287_10K_2018.htm	113	In addition, the U.S. Environmental Protection Agency (the “EPA”) has stated that climate change may lead to the increased frequency and severity of extreme weather events.
950882	0	1724009/1724009_10K_2018.htm	43	Higher oil and natural gas prices generally stimulate demand and result in increased process for drilling rigs, crews and associated supplies, equipment and services.Shortages of field personnel and equipment or price increases could hinder the ability to conduct operations.
952210	0	1212458/1212458_10K_2018.htm	11	• future accounting pronouncements or changes in our accounting policies.
962063	0	1730430/1730430_10K_2018.htm	26	As a result, we believed that the FDA’s communications with MedImmune suggested that the FDA could find an acceptable risk/benefit for a clinical trial of mavrilimumab in the United States in GCA, a disease with high morbidity and limited treatment options.
962356	0	1631650/1631650_10K_2018.htm	99	Furthermore, environmental laws and regulations are complex, change frequently and have tended to become more stringent.
963141	0	1718108/1718108_10K_2018.htm	283	• delaying, deferring or preventing a change of control of us;.
963483	0	17313/17313_10K_2018.htm	49	In June 2016, the United Kingdom held a referendum in which voters approved an exit from the European Union
970022	0	1435049/1435049_10K_2018.htm	53	Further, new studies may change the estimated incidence or prevalence of these cancers.
975072	1	1739445/1739445_10K_2018.htm	86	There is also a potential for climate change legislation and regulation that could adversely impact the cost of certain manufacturing inputs, including the cost of energy and electricity.
984416	0	1746129/1746129_10K_2018.htm	64	We have benefited from the recent low interest rate environment, which has provided us with high net interest margins which we use to grow our business.
987049	0	1747009/1747009_10K_2018.htm	221	A consensus on the characteristics, such as the effective tax rate, or enactment of a state severance tax has yet to be reached.
989873	0	1559053/1559053_10K_2018.htm	183	Current and future legislation may significantly change the approval requirements in ways that could involve additional costs and cause delays in obtaining approvals.
999731	1	225648/225648_10K_2018.htm	20	There has been substantial debate recently in the United States and abroad in the context of environmental and energy policies affecting climate change, the outcome of which could have a positive or negative influence on our existing business and our prospects for growing our business.
1001432	0	23197/23197_10K_2018.htm	113	A change in our relationship with our large wireless carrier customers could have a material adverse effect.
1005265	1	27093/27093_10K_2018.htm	40	Regulationsand pending legislation governing issues involving climate change could result in increased operating costs, which could havea material adverse effect on our business.
1011251	1	313927/313927_10K_2018.htm	33	As climate change, ingredients, packaging and other sustainability concerns become more prevalent, federal, state and local governments and our customers, consumers and investors are increasingly sensitive to these issues.
1017741	1	1738827/1738827_10K_2018.htm	80	Moreover, incentives to conserve energy or use alternative energy sources could reduce demand for oil and natural gas.
1020084	0	33185/33185_10K_2018.htm	66	Changes to tax laws can have immediate impacts, either favorable or unfavorable, on our
1020969	0	34563/34563_10K_2018.htm	5	We consider our roasting and blending methods essential to the flavor and richness of our coffees and, therefore, essential to our brand.
1028231	0	356130/356130_10K_2018.htm	23	• an unfavorable change in the liquidity of an investment, or.
1028837	0	3570/3570_10K_2018.htm	30	• there is a change in the expected differential between the underlying price in the hedging agreement and actual prices received.
1032653	1	37785/37785_10K_2018.htm	5	Any of these actions could adversely impact our net sales, undermine goodwill established with our customers, damage commercial prospects for our products and materially adversely affect our results of operations.. • Climate change regulation - Changes in the regulation of greenhouse gases, depending on their nature and scope, could subject our manufacturing operations to significant additional costs or limits on operations.. • Fluctuations in commodity prices - Our operating results could be significantly affected by the cost of commodities.
1035729	1	42316/42316_10K_2018.htm	39	However, the physical effects of climate change could have a material adverse effect on our properties, operations and business.
1036801	1	4447/4447_10K_2018.htm	11	In addition, our production is sold to third parties that produce petroleum fuels, which through normal end user consumption result in the emission of greenhouse gases.
1038266	1	48039/48039_10K_2018.htm	45	Although the U.S. Congress has previously considered legislation to reduce GHG emissions, federal legislative action appears unlikely at this time.
1039898	0	4962/4962_10K_2018.htm	75	Even if we were not required to change our merchant agreements, changes in Visa’s and Mastercard’s policies or practices as a result of legal proceedings, lawsuit settlements or regulatory actions pending against them could result in changes to our business practices and materially and adversely impact our profitability.
1044713	1	56047/56047_10K_2018.htm	12	Although the EPA has stated a preference that greenhouse gas regulation be based on new federal legislation rather than the existing Clean Air Act, many sources of greenhouse gas emissions may be regulated without the need for further legislation.
1047616	0	60086/60086_10K_2018.htm	106	• 🌑   the amount of debt and the amount it must pay to service its debt obligations could place Diamond Offshore ata competitive disadvantage compared to its competitors that have less debt; and.
1051502	0	64803/64803_10K_2018.htm	50	In addition, the rapid pace of change as the industry evolves towards a consumer-focused retail marketplace, including Insurance Exchanges, and the
1055705	0	700923/700923_10K_2018.htm	45	Current or future market conditions, including losses incurred in the construction industry or as a result of large corporate bankruptcies, as well as changes in our sureties’ assessment of our operating and financial risk, could cause our surety providers and lenders to decline to issue or renew, or substantially reduce the amount of, bid or performance bonds for our work and could increase our costs associated withcollateral.
1055857	1	700923/700923_10K_2018.htm	75	Additionally, legislative and regulatory responses related to climate change and new interpretations of existing laws through climate change litigation may also negatively impact our operations.
1061906	0	708955/708955_10K_2018.htm	55	Moreover, as technology and cyberattacks change over time, we must continually monitor and change systems to guard against new threats.
1062007	0	1598646/1598646_10K_2018.htm	92	Additionally, controls can be circumvented by the individual acts of some persons, by collusion of two or more people or by an unauthorized override of the controls.
1067375	0	1624322/1624322_10K_2018.htm	4	All of these factors are detrimental to our business, and the interplay between these factors can be complex and unpredictable.
1068447	0	715957/715957_10K_2018.htm	77	If its goodwill or other intangible assets become impaired in the future, Dominion Energy may be required to record a significant, non-cash charge to earnings and reduce itsshareholders’ equity.
1069451	0	716634/716634_10K_2018.htm	3	While several private lawsuits are currently pending challenging the practice of certain competitors to prevent or limit their access to film product, these are private lawsuits.
1071523	0	1724344/1724344_10K_2018.htm	94	These provisions could discourage potential acquisition proposals and could delay or prevent a change in control transaction.
1072687	0	719413/719413_10K_2018.htm	75	For those that exist, we face strong competition from other mining companies, many of which have greater financial resources than we do.
1080390	0	730263/730263_10K_2018.htm	95	•   Changes in global economic conditions or general market conditions in our industry;.
1082348	0	732834/732834_10K_2018.htm	57	Business—Regulation of the Crude Oil and Natural Gas Industry for a discussion of regulations impacting the transportation of crude oil and natural gas.
1082396	1	732834/732834_10K_2018.htm	70	Finally, some scientists have concluded that increasing concentrations of greenhouse gases in the Earth’s atmosphere may produce climate changes that have significant physical effects, such as increased frequency and severity of storms, droughts, floods or other climatic events.
1083698	1	738214/738214_10K_2018.htm	45	Our business is affected by greenhouse gas and climate changeregulation.
1084006	0	740663/740663_10K_2018.htm	19	In addition, the Bank can purchase overnight federal funds under its existing line and the Corporation can raise funds through its DRIP.
1087269	1	745308/745308_10K_2018.htm	68	In addition to hurricanes, the occurrence of other natural disasters and climate conditions in Florida, such as tornadoes, floods, fires, unusually heavy or prolonged rain, droughts, extreme heat, or other adverse weather events could have a material adverse effect on our ability to develop and sell properties or realize income from our projects.
1087647	1	745732/745732_10K_2018.htm	42	Risks in importing and selling such merchandise include import duties and quotas, compliance with anti-dumping regulations, economic uncertainties and adverse economic conditions (including inflation, recession, and exchange rate fluctuations), foreign government regulations, employment and labor matters, concerns relating to human rights, working conditions, and other issues in factories or countries where merchandise is produced, transparency of sourcing and supply chains, exposure on product warranty and intellectual property issues, consumer perceptions of the safety of imported merchandise, wars and fears of war, political unrest, natural disasters, regulations to address climate change, and trade restrictions.
1094449	0	763901/763901_10K_2018.htm	41	For 2018, the FDIC deposit insurance expense of Popular totaled $ 28 million.
1096987	0	76605/76605_10K_2018.htm	3	The RV, MH, marine and industrial markets in which we operate are subject to cycles of growth and contraction in consumer demand, and volatility in production levels, shipments, sales and operating results, due to external factors such as general economic conditions, consumer confidence, employment rates, financing availability, interest rates, inflation, fuel prices, and other economic conditions affecting consumer demand and discretionary spending.
1100960	0	77360/77360_10K_2018.htm	78	Also, the tax laws of the U.S., the U.K., Ireland and other jurisdictions could change in the future, and such changes could cause a material change in our worldwide effective corporate tax rate.
1101109	0	315852/315852_10K_2018.htm	55	For example, in December 2016, the EPA released its final report on the potential impacts of hydraulic fracturing on drinking water resources.
1104240	1	776867/776867_10K_2018.htm	38	If you are a U.S. person who might be a U.S. 10% shareholder, we encourage you to consult your own tax advisor concerning the CFC rules.
1109016	1	78890/78890_10K_2018.htm	44	Furthermore, the potential effects of climate change and related regulation on our customers are highly uncertain and may adversely affect our operations.
1115798	0	1300514/1300514_10K_2018.htm	42	The LIBOR calculation method may change and LIBOR is expected to be phased out after 2021.
1116531	1	799165/799165_10K_2018.htm	70	Current and future legislation or regulation relating to climate change or hydraulic fracturing could negatively affect the exploration and production of oil and gas and adversely affect demand for our services.
1119048	0	805022/805022_10K_2018.htm	19	Our distributable cash flow does not depend solely on profitability, which is affected by non-cash items.
1121810	0	811212/811212_10K_2018.htm	49	International operations also may be limited or disrupted by political, economic or social instability, price controls, trade restrictions and changes in tariffs as ordered by various governmental agencies.
1121901	0	811240/811240_10K_2018.htm	7	We believe these disruptions are likely to have an ongoing adverse effect on the world economy.
1122202	1	768408/768408_10K_2018.htm	80	Proposed and existing legislative efforts to control or limit greenhouse gas emissions could affect our energy source and supply choices as well as increase the cost of energy and raw materials derived from sources that generate greenhouse gas emissions.
1131579	1	82020/82020_10K_2018.htm	23	There is no assurance that changes in the law or regulations will not be adopted, such as the imposition of a carbon tax, a cap-and-trade program requiring companies to purchase carbon credits, or other measures that would require reductions in emissions or changes to raw materials, fuel use or production rates.
1132512	0	821130/821130_10K_2018.htm	89	Any litigation to determine the validity of claims that U.S. Cellular’s products or services infringe or may infringe intellectual property rights of another, regardless of their merit or resolution, could be costly and divert the effort and attention of U.S. Cellular’s management and technical personnel.
1133148	0	823768/823768_10K_2018.htm	20	In addition, other countries have limited or restricted the import of certain recyclables.
1136266	0	833079/833079_10K_2018.htm	21	Another decline in the homebuilding market may require us to re-evaluate the value of our land holdings and we could incur additional impairment charges, which would decrease both the book value of our assets and stockholders’ equity.
1150315	0	860413/860413_10K_2018.htm	27	We may be adversely affected by declining oil and gas prices, and declining demand for coal.
1153432	0	861884/861884_10K_2018.htm	69	Factors that may be considered a change in circumstances, indicating that the carrying value of our goodwill or indefinite‑lived intangible assets may not be recoverable, include a decline in stock price and market capitalization, declines in the market conditions of our products, viability of end markets (such as the energy market in which we have downsized a business and lower oil prices impacted the demand for the products we sell - see discussion of our 2018 and 2016 impairment charges in Note 18 — “Impairment and Restructuring Charges” of Part II, Item 8 “Financial Statements and Supplementary Data” ), loss of customers, reduced future cash flow estimates, and slower growth rates in our industry.
1159317	0	871763/871763_10K_2018.htm	2	• failure to keep pace with technological change and marketplace demand in the development and implementation of our services and solutions;.
1163271	0	1658566/1658566_10K_2018.htm	104	Conservation measures and technological advances could reduce demand for oil and natural gas.
1163353	1	874499/874499_10K_2018.htm	132	In addition, substantial limitations on GHG emissions could adversely affect demand for the oil and natural gas we produce.
1163360	1	1602065/1602065_10K_2018.htm	134	Moreover, there has been public discussion that climate change may be associated with extreme weather conditions such as more intense hurricanes, thunderstorms, tornadoes and snow or ice storms, as well as rising sea levels.
1170242	0	1539029/1539029_10K_2018.htm	105	In addition, while it is our policy to require our employees and contractors who may be involved in the development of intellectual property to execute agreements assigning such intellectual property to us, we may be unsuccessful in executing such an agreement with each party who in fact develops intellectual property that we regard as our own.
1174966	0	878927/878927_10K_2018.htm	16	To date, several governments, including the European Union, China, and India, have imposed tariffs on certain goods imported from the United States.
1176239	0	879585/879585_10K_2018.htm	28	Some of these changes have had a significant impact on our operations in India in the short-term.
1179073	0	88205/88205_10K_2018.htm	48	Governmental laws and regulations could negatively affect our business.
1179600	1	882095/882095_10K_2018.htm	97	Our worldwide operations, third party manufacturers or corporate partners could be subject to business interruptions stemming from natural or man-made disasters, including those related to climate change, for which we or they may be uninsured or inadequately insured.
1179604	0	882095/882095_10K_2018.htm	99	We are dependent upon information technology systems, infrastructure and data, including our Kite Konnect platform, which is critical to ensure chain of identity and chain of custody of Yescarta.
1179979	0	882104/882104_10K_2018.htm	87	Despite the time, effort and cost, we cannot assure you that any particular device will be approved or cleared by the FDA.
1183012	0	883948/883948_10K_2018.htm	53	Current accounting guidance requires goodwill to be tested for impairment, and the Company performs such impairment analysis at least annually.
1184990	0	884713/884713_10K_2018.htm	26	In addition, because our financial statements are denominated in U.S. dollars, changes in currency exchange rates between the U.S. dollar and other currencies have had, and will continue to have, an impact on our results of operations.
1185336	1	884887/884887_10K_2018.htm	24	Increases in the frequency, severity or duration of severe weather events, including those related to climate change, could exacerbate their impact and cause further disruption to our operations or make certain destinations less desirable.
1188816	0	1355754/1355754_10K_2018.htm	143	The impact of this tax reform on holders of our common stock is also uncertain and could be adverse.
1189157	1	886835/886835_10K_2018.htm	38	At this stage, we cannot predict the impact of these or other initiatives on our or our customers operations, nor can we predict whether, or which of, other currently pending greenhouse gas emission proposals will be adopted, or what other actions may be taken by domestic or international regulatory bodies.
1189898	0	887247/887247_10K_2018.htm	45	In addition, the law or regulatory policies governing pharmaceuticals may change.
1193319	0	889331/889331_10K_2018.htm	33	The Company’s operating activities are subject to a number of risks generally associated with multi-national operations, including risks relating to the following:.
1194531	1	890319/890319_10K_2018.htm	4	• changes in the global, national, regional, and/or local economic and geopolitical climates.
1195121	0	890394/890394_10K_2018.htm	56	A failure to fully enforce the royalty provisions of our license agreements could cause our revenue to decrease and impede our ability to achieve and maintain profitability.
1196488	0	89089/89089_10K_2018.htm	22	The surety bonds are used for various business purposes; however, the majority of the surety bonds issued and outstanding have been issued to support our preneed funeral and cemetery activities.
1197009	0	1488039/1488039_10K_2018.htm	22	We may not be able to adequately manage and oversee the manufacturers we choose, they may not perform as agreed or they may terminate their agreements with us.
1197297	0	891293/891293_10K_2018.htm	100	• such regulatory agencies might change their approval policies or adopt new regulations.
1201641	0	894627/894627_10K_2018.htm	69	The nature of our operations exposes us to further possible litigation claims in the future.
1204714	0	896264/896264_10K_2018.htm	13	Additionally, we are subject to the risk that the regulations, or a regulator's interpretation and enforcement of the regulations, could change.
1206034	1	896985/896985_10K_2018.htm	103	In addition, we cannot control the actions of our third party manufacturers or the public’s perceptions of them, nor can we assure that these manufacturers will conduct their businesses using climate change proactive or sustainable practices.
1206779	0	898174/898174_10K_2018.htm	41	• potential reduction in opportunities resulting from market access restrictions.
1225816	0	914025/914025_10K_2018.htm	96	• recent economic sanctions imposed, and the potential for additional economic sanctions, by the United States as well as the actual and threatened retaliatory responses by impacted nations, some of which may affect or materially delay our ability to import or sell all or a portion of our products into impacted countries;.
1229648	0	916540/916540_10K_2018.htm	19	We also require a significant amount of electricity in operating certain of our facilities, a disruption of which or a significant increase in the cost of which could have a material adverse effect on the business and results of operations of the affected facility.
1229667	0	916540/916540_10K_2018.htm	27	• change in existing trade agreements, such as the North American Free Trade Agreement (NAFTA), which could negatively impact our business;.
1233519	0	920448/920448_10K_2018.htm	38	In addition, effective January 1, 2018, we began to recognize a portion of the arrangement fees allocated to our QuickSilver software licenses as revenue upon delivery resulting in revenues for these QuickSilver arrangements generally being recorded in an earlier period than prior to the adoption of Topic 606.
1237834	0	1593936/1593936_10K_2018.htm	284	This choice of forum provision may limit a stockholder’s ability to bring a claim in a judicial forum that it finds favorable for disputes with us or our directors, officers or other employees, which may discourage such lawsuits against us and our directors, officers and employees.
1241499	0	926326/926326_10K_2018.htm	106	We are dependent on technologies provided by third-party vendors, the loss of which could negatively and materially affect our ability to market, sell, or distribute our products.
1255035	0	1286043/1286043_10K_2018.htm	36	In addition, we may be required to make distributions to shareholders at disadvantageous times or when we do not have funds readily available for distribution.
1255284	0	944695/944695_10K_2018.htm	50	Although we have estimated the effect that the TCJA will have on our current deferred tax position, there can be no assurance that these estimates won’t change based on new interpretations of the TCJA or in the event that new information related to our current tax position becomes known.
1257825	0	946644/946644_10K_2018.htm	48	Toprotect our rights, we require all employees and certain consultants to enter into confidentiality agreements with us.
1266053	0	9984/9984_10K_2018.htm	33	We assess whether there has been an impairment in the value of our goodwill during each calendar year or sooner if triggering events warrant.