TITLE: Impact of preventive oral health interventions during the prenatal care on preterm delivery, an integrative review protocol.
AUTHORS: Cristina Dutra Vieira, Andreza Nayla de Assis Aguiar, Camila Aparecida Silva de Oliveira Lima, Zilma Reis

[DESCRIPTION]
<div class = "text-blocks"><div class = "text-block">Background: Spontaneous preterm birth is a worldwide concern due to the impact on infant mortality. Good quality of antenatal care pregnancy has the potential to reduce the rate of prematurity and improve neonatal outcome. Periodontal disease suppose to affect preterm labor. The impact of interventions to promote the oral health of pregnant women in the prevention of preterm birth is still controverse.</div><div class = "text-block">Objective: To assess evidence on the impact of oral health interventions during prenatal care in preventing spontaneous preterm birth.</div><div class = "text-block">Methods: A comprehensive integrative literature review to respond to the primary research question: Which the interventions to promote oral health during antenatal care associated with higher duration of gestation? </div><div class = "text-block">First version, March-09-2019.</div><div class = "text-block">Stage of review: Ongoin</div></div>

[STEPS]
?. Search strategyThe search strategy was performed using the following keyword combination for the composition of key-words and descriptors of health: Health Education; Health Education, Dental; Health Promotion; Pregnant Women; Pregnancy Outcome; Infant, Low Birth Weight; Premature Birth; Infant, Small for Gestational Age; Gestational Age; Periodontitis; Periodontal Diseases; Periodontal health; Periodontal treatment; Periodontal therapy; Number of teeth; Oral Hygiene.
?. Data synthesisThe authors prepared the review protocol using the application software StArt (Systematic Review System).Ref: 14. Whitlock EP, Lin JS, Chou R, et al. Using existing systematic reviews in complex systematic reviews. Ann Intern Med. 2008;148(10):776–82.
?. SuportThere is no finantial suport.ZSNR is under period of CAPES-Brazil grant (PVE 88881.172810/2018-01) The authors declare no conflit of interest
?. Eligibility criteriaStudies describing the effect of oral health preventive interventions during prenatal care.
?. Information sourcesThe authors will conduct a comprehensive search for published evidence in the BBO, CUMED, IBECS, BINACIS, SOF, PubMed, Lilacs, Scielo, BVS library databases.
?. Study records - Selection processSpecified inclusion criteria were: Human pregnancy, Oral or dental health; Oral health education; Health promotion; Premature birth outcome. Exclusion criteria were: nonhuman pregnancy; Opinion of specialist; Literature review or recommendations without scientific evidence; No clinical approach; Protocols of research without results; No intervention in oral health.
?. Data itemsDuring data extraction the variable were:Institution= Private, Public, University, Philanthropic, Non applicable.Population (sampling)= Multicentric, National, Regional, Local, None-applicable, Systematic Review.Groups of study: inclusion criteria Type of approach= Prevention, Education, Treatment, Health promotion, Diagnosis, Educational media, Non applicable.Type of source= Sistematic Review, Clinical Trial (randomised), Clinical Trial (no-randomised), Observational study, Thesis or dissertation, Specialist opinion, Chapter of book, Protocol of scientific society, Literature Review, Other source.Dental approach= Periodontal treatment, Dental scale and polish, Dental hygiene, Periodontal therapy, Periodontal disease, Periodontitis, Gengivitis, Dentist evaluation, Non applicable (Disease index).Moment of approach= Initial prenatal care, During prenatal care, After birth, Premature birth risk factors, Premature birth, Non applicable.Duration of the approach= Once, More than one, Non applicableNumber of assessment (during approch) = NumberOutcomes= Premature rate or diagnosis, Costs reduction, Birth weight, Gestational age, Comprehensiveness of action, Non applicable.Lessons learnt; Limitations (publication)
?. Outcomes and prioritizationDuring selection process the priority are: Clinical trials (randomised / non-randomised / after-before), Systematic reviews, Case-control studies.