iGEM 2018 — Team Fudan-CHINA

[![](https://static.igem.org/mediawiki/2018/8/8b/HQ_page_logo.jpg)](https://2018.igem.org)

# Team:Fudan-CHINA/Notebook

* [![](https://static.igem.org/mediawiki/2018/6/62/T--Fudan-CHINA--stepLogo1.png)](https://2018.igem.org/Team%3AFudan-CHINA)
* [Fudan-CHINA](https://2018.igem.org/Team%3AFudan-CHINA)
* [Awards](https://2018.igem.org/Team%3AFudan-CHINA/Awards)
* [Team](https://2018.igem.org/Team%3AFudan-CHINA/Team)
  + [Team](https://2018.igem.org/Team%3AFudan-CHINA/Team)
  + [Attributions](https://2018.igem.org/Team%3AFudan-CHINA/Attributions)
* [Notebook](https://2018.igem.org/Team%3AFudan-CHINA/Notebook)
* [Human Practices](https://2018.igem.org/Team%3AFudan-CHINA/Human_Practices)
  + [Overview](https://2018.igem.org/Team%3AFudan-CHINA/Human_Practices)
  + [Silver HP](https://2018.igem.org/Team%3AFudan-CHINA/Human_Practices#mainTitle2)
  + [Integrated HP](https://2018.igem.org/Team%3AFudan-CHINA/Human_Practices#mainTitle3)
  + [Education & Engagement](https://2018.igem.org/Team%3AFudan-CHINA/Public_Engagement)
  + [Collaborations](https://2018.igem.org/Team%3AFudan-CHINA/Collaborations)
  + [Safety](https://2018.igem.org/Team%3AFudan-CHINA/Safety)
* [Parts](https://2018.igem.org/Team%3AFudan-CHINA/Part_List)
  + [Improved Part](https://2018.igem.org/Team%3AFudan-CHINA/Improve)
  + [Best New Basic Part](https://2018.igem.org/Team%3AFudan-CHINA/Basic_Part)
  + [Best New Composite Part](https://2018.igem.org/Team%3AFudan-CHINA/Composite_Part)
  + [Best Part Collection](https://2018.igem.org/Team%3AFudan-CHINA/Part_Collection)
  + [Part List](https://2018.igem.org/Team%3AFudan-CHINA/Part_List)
* [Model](https://2018.igem.org/Team%3AFudan-CHINA/Model)
  + [Model](https://2018.igem.org/Team%3AFudan-CHINA/Model)
  + [Software](https://2018.igem.org/Team%3AFudan-CHINA/Software)
* [Results](https://2018.igem.org/Team%3AFudan-CHINA/Results)
  + [Overview](https://2018.igem.org/Team%3AFudan-CHINA/Results)
  + [STEP System Test](https://2018.igem.org/Team%3AFudan-CHINA/Results_STEP)
  + [Receptor Optimisation](https://2018.igem.org/Team%3AFudan-CHINA/Results_PR)
  + [Demonstrate](https://2018.igem.org/Team%3AFudan-CHINA/Demonstrate)
  + [Interlab](https://2018.igem.org/Team%3AFudan-CHINA/InterLab)
* [Project](https://2018.igem.org/Team%3AFudan-CHINA/Design)
  + [Background](https://2018.igem.org/Team%3AFudan-CHINA/Background)
  + [Design](https://2018.igem.org/Team%3AFudan-CHINA/Design)
  + [Applied Design](https://2018.igem.org/Team%3AFudan-CHINA/Applied_Design)

![](https://static.igem.org/mediawiki/2018/7/7e/T--Fudan-CHINA--notebook.jpg)

Notebook

"All human wisdom is summed up in two words, wait and hope."

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# Useful Links

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[iGEM Main Page](https://2018.igem.org/Main_Page)

[iGEM Special Pages](https://2018.igem.org/Main_Page)

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# Email

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igem@fudan.edu.cn

kfjin16@fudan.edu.cn

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# Address

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G604, School of Life Sciences, Fudan University
2005 Songhu Road, Yangpu, Shanghai, China

![](https://static.igem.org/mediawiki/2018/f/fc/T--Fudan-CHINA--teamBadgeWhite.png)


[![](https://static.igem.org/mediawiki/2018/8/8b/HQ_page_logo.jpg)](https://2018.igem.org)

# Team:Fudan-CHINA/Experiments

* [![](https://static.igem.org/mediawiki/2018/6/62/T--Fudan-CHINA--stepLogo1.png)](https://2018.igem.org/Team%3AFudan-CHINA)
* [Fudan-CHINA](https://2018.igem.org/Team%3AFudan-CHINA)
* [Awards](https://2018.igem.org/Team%3AFudan-CHINA/Awards)
* [Team](https://2018.igem.org/Team%3AFudan-CHINA/Team)
  + [Team](https://2018.igem.org/Team%3AFudan-CHINA/Team)
  + [Attributions](https://2018.igem.org/Team%3AFudan-CHINA/Attributions)
* [Notebook](https://2018.igem.org/Team%3AFudan-CHINA/Notebook)
* [Human Practices](https://2018.igem.org/Team%3AFudan-CHINA/Human_Practices)
  + [Overview](https://2018.igem.org/Team%3AFudan-CHINA/Human_Practices)
  + [Silver HP](https://2018.igem.org/Team%3AFudan-CHINA/Human_Practices#mainTitle2)
  + [Integrated HP](https://2018.igem.org/Team%3AFudan-CHINA/Human_Practices#mainTitle3)
  + [Education & Engagement](https://2018.igem.org/Team%3AFudan-CHINA/Public_Engagement)
  + [Collaborations](https://2018.igem.org/Team%3AFudan-CHINA/Collaborations)
  + [Safety](https://2018.igem.org/Team%3AFudan-CHINA/Safety)
* [Parts](https://2018.igem.org/Team%3AFudan-CHINA/Part_List)
  + [Improved Part](https://2018.igem.org/Team%3AFudan-CHINA/Improve)
  + [Best New Basic Part](https://2018.igem.org/Team%3AFudan-CHINA/Basic_Part)
  + [Best New Composite Part](https://2018.igem.org/Team%3AFudan-CHINA/Composite_Part)
  + [Best Part Collection](https://2018.igem.org/Team%3AFudan-CHINA/Part_Collection)
  + [Part List](https://2018.igem.org/Team%3AFudan-CHINA/Part_List)
* [Model](https://2018.igem.org/Team%3AFudan-CHINA/Model)
  + [Model](https://2018.igem.org/Team%3AFudan-CHINA/Model)
  + [Software](https://2018.igem.org/Team%3AFudan-CHINA/Software)
* [Results](https://2018.igem.org/Team%3AFudan-CHINA/Results)
  + [Overview](https://2018.igem.org/Team%3AFudan-CHINA/Results)
  + [STEP System Test](https://2018.igem.org/Team%3AFudan-CHINA/Results_STEP)
  + [Receptor Optimisation](https://2018.igem.org/Team%3AFudan-CHINA/Results_PR)
  + [Demonstrate](https://2018.igem.org/Team%3AFudan-CHINA/Demonstrate)
  + [Interlab](https://2018.igem.org/Team%3AFudan-CHINA/InterLab)
* [Project](https://2018.igem.org/Team%3AFudan-CHINA/Design)
  + [Background](https://2018.igem.org/Team%3AFudan-CHINA/Background)
  + [Design](https://2018.igem.org/Team%3AFudan-CHINA/Design)
  + [Applied Design](https://2018.igem.org/Team%3AFudan-CHINA/Applied_Design)

# Experiments

Describe the research, experiments, and protocols you used in your iGEM project. These should be detailed enough for another team to repeat your experiments.

Please remember to put all characterization and measurement data for your parts on the corresponding Registry part pages.

### What should this page contain?

* Protocols
* Experiments
* Documentation of the development of your project

### Inspiration

* [2014 Colombia](https://2014.igem.org/Team%3AColombia/Protocols)
* [2014 Imperial](https://2014.igem.org/Team%3AImperial/Protocols)
* [2014 Caltech](https://2014.igem.org/Team%3ACaltech/Project/Experiments)

[![](https://static.igem.org/mediawiki/2018/8/8b/HQ_page_logo.jpg)](https://2018.igem.org)

# Team:Fudan-CHINA/Results

* [![](https://static.igem.org/mediawiki/2018/6/62/T--Fudan-CHINA--stepLogo1.png)](https://2018.igem.org/Team%3AFudan-CHINA)
* [Fudan-CHINA](https://2018.igem.org/Team%3AFudan-CHINA)
* [Awards](https://2018.igem.org/Team%3AFudan-CHINA/Awards)
* [Team](https://2018.igem.org/Team%3AFudan-CHINA/Team)
  + [Team](https://2018.igem.org/Team%3AFudan-CHINA/Team)
  + [Attributions](https://2018.igem.org/Team%3AFudan-CHINA/Attributions)
* [Notebook](https://2018.igem.org/Team%3AFudan-CHINA/Notebook)
* [Human Practices](https://2018.igem.org/Team%3AFudan-CHINA/Human_Practices)
  + [Overview](https://2018.igem.org/Team%3AFudan-CHINA/Human_Practices)
  + [Silver HP](https://2018.igem.org/Team%3AFudan-CHINA/Human_Practices#mainTitle2)
  + [Integrated HP](https://2018.igem.org/Team%3AFudan-CHINA/Human_Practices#mainTitle3)
  + [Education & Engagement](https://2018.igem.org/Team%3AFudan-CHINA/Public_Engagement)
  + [Collaborations](https://2018.igem.org/Team%3AFudan-CHINA/Collaborations)
  + [Safety](https://2018.igem.org/Team%3AFudan-CHINA/Safety)
* Parts
  + [Improved Part](https://2018.igem.org/Team%3AFudan-CHINA/Improve)
  + [Best New Basic Part](https://2018.igem.org/Team%3AFudan-CHINA/Basic_Part)
  + [Best New Composite Part](https://2018.igem.org/Team%3AFudan-CHINA/Composite_Part)
  + [Best Part Collection](https://2018.igem.org/Team%3AFudan-CHINA/Part_Collection)
  + [Part List](https://2018.igem.org/Team%3AFudan-CHINA/Part_List)
* [Model](https://2018.igem.org/Team%3AFudan-CHINA/Model)
  + [Model](https://2018.igem.org/Team%3AFudan-CHINA/Model)
  + [Software](https://2018.igem.org/Team%3AFudan-CHINA/Software)
* [Results](https://2018.igem.org/Team%3AFudan-CHINA/Results)
  + [Overview](https://2018.igem.org/Team%3AFudan-CHINA/Results)
  + [STEP System Test](https://2018.igem.org/Team%3AFudan-CHINA/Results_STEP)
  + [Receptor Optimisation](https://2018.igem.org/Team%3AFudan-CHINA/Results_PR)
  + [Demonstrate](https://2018.igem.org/Team%3AFudan-CHINA/Demonstrate)
  + [Interlab](https://2018.igem.org/Team%3AFudan-CHINA/InterLab)
* [Project](https://2018.igem.org/Team%3AFudan-CHINA/Design)
  + [Background](https://2018.igem.org/Team%3AFudan-CHINA/Background)
  + [Design](https://2018.igem.org/Team%3AFudan-CHINA/Design)
  + [Applied Design](https://2018.igem.org/Team%3AFudan-CHINA/Applied_Design)

![](https://static.igem.org/mediawiki/2018/6/63/T--Fudan-CHINA--bkg3.jpg)

Results Overview

"No road of flowers lead to glory."

To develop and optimise our STEP system to achieve the goal of efficient tumour marker recognition, we set out to test the whole system in human cell lines, and at the same time combine computational design and wet lab experiment to optimise existing receptors.

We successfully proved that the STEP receptors can appropriately locate across the cell membrane, and that they are able to bind to activate the downstream receptor when target ligand is added.

![](https://static.igem.org/mediawiki/2018/2/2f/T--Fudan-CHINA--ResOv01.png)

STEP System Test

[READ MORE](https://2018.igem.org/Team%3AFudan-CHINA/Results_STEP)

![](https://static.igem.org/mediawiki/2018/8/89/T--Fudan-CHINA--ResOv02.png)

Receptor Optimisation

[READ MORE](https://2018.igem.org/Team%3AFudan-CHINA/Results_PR)

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# Useful Links

---

![]()

# Email

---

igem@fudan.edu.cn

kfjin16@fudan.edu.cn

![]()

# Address

---

G604, School of Life Sciences, Fudan University
2005 Songhu Road, Yangpu, Shanghai, China

![](https://static.igem.org/mediawiki/2018/f/fc/T--Fudan-CHINA--teamBadgeWhite.png)