Target family: Prolactin-releasing peptide receptor (type: gpcr)
Target: PrRP receptor

Ligand: [125I]PrRP-20 (human) (Peptide)
Interaction type: Agonist
Action: Full agonist
Ligand approved: no
Median affinity:  pKd
Reference (Journal): Characterization of the binding of [(125)I]-human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor.
Published in: Br J Pharmacol

Ligand: PTHrP (Peptide)
Interaction type: Agonist
Action: Full agonist
Ligand approved: no
Median affinity:  -

Ligand: PrRP-31 (Peptide)
Interaction type: Agonist
Action: Full agonist
Ligand approved: no
Median affinity: 9.5 pKi
Reference (Journal): Characterization of the binding of [(125)I]-human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor.
Published in: Br J Pharmacol

Ligand: PrRP-31 (Peptide)
Interaction type: Agonist
Action: Full agonist
Ligand approved: no
Primary target: no
Median affinity:  pKi
Reference (Journal): Characterization of the binding of [(125)I]-human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor.
Published in: Br J Pharmacol

Ligand: PrRP-31 (Peptide)
Interaction type: Agonist
Action: Full agonist
Ligand approved: no
Primary target: no
Median affinity:  pKi
Reference (Journal): Prolactin releasing peptide has high affinity and efficacy at neuropeptide FF2 receptors.
Published in: J Pharmacol Exp Ther

Ligand: PrRP-(24-31) (human) (Peptide)
Interaction type: Agonist
Action: Full agonist
Ligand approved: no
Median affinity: 7.3 pKi
Reference (Journal): Prolactin releasing peptide has high affinity and efficacy at neuropeptide FF2 receptors.
Published in: J Pharmacol Exp Ther

Ligand: PrRP-20 (Peptide)
Interaction type: Agonist
Action: Full agonist
Ligand approved: no
Median affinity: 9.7 pKi
Reference (Journal): Characterization of the binding of [(125)I]-human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor.
Published in: Br J Pharmacol

Ligand: PrRP-20 (Peptide)
Interaction type: Agonist
Action: Full agonist
Ligand approved: no
Primary target: no
Median affinity:  pKi
Reference (Journal): Characterization of the binding of [(125)I]-human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor.
Published in: Br J Pharmacol

Ligand: PrRP-20 (Peptide)
Interaction type: Agonist
Action: Full agonist
Ligand approved: no
Primary target: no
Median affinity:  pKi
Reference (Journal): Prolactin releasing peptide has high affinity and efficacy at neuropeptide FF2 receptors.
Published in: J Pharmacol Exp Ther

Ligand: NPY-(18-36) (human, pig) (Peptide)
Interaction type: Agonist
Action: Partial agonist
Ligand approved: no
Median affinity: 5.1 pKi
Reference (Journal): Prolactin releasing peptide has high affinity and efficacy at neuropeptide FF2 receptors.
Published in: J Pharmacol Exp Ther

Ligand: neuropeptide Y (Peptide)
Interaction type: Antagonist
Action: Antagonist
Ligand approved: no
Median affinity: 5.4 pKi
Reference (Journal): Origin of the prolactin-releasing hormone (PRLH) receptors: evidence of coevolution between PRLH and a redundant neuropeptide Y receptor during vertebrate evolution.
Published in: Genomics

Ligand: [125I]PrRP31 (Peptide)
Interaction type: Agonist
Action: Full agonist
Ligand approved: no
Primary target: no
Median affinity:  -
Reference (Journal): Characterization of a naturally-occurring polymorphism in the UHR-1 gene encoding the putative rat prolactin-releasing peptide receptor.
Published in: Peptides