Target family: Aminoacyl-tRNA synthetases (type: other_protein)
Target: Plasmodium falciparum lysyl-tRNA synthetase

Ligand: cladosporin (Natural product)
Interaction type: None
Action: None
Ligand approved: no
Primary target: no
Median affinity: 7.409999847412109 pIC50
Reference (Journal): Selective and specific inhibition of the plasmodium falciparum lysyl-tRNA synthetase by the fungal secondary metabolite cladosporin.
Published in: Cell Host Microbe

Ligand: cladosporin (Natural product)
Interaction type: None
Action: None
Ligand approved: no
Primary target: no
Median affinity: 7.340000152587891 pIC50
Reference (Journal): Selective and specific inhibition of the plasmodium falciparum lysyl-tRNA synthetase by the fungal secondary metabolite cladosporin.
Published in: Cell Host Microbe

Ligand: cladosporin (Natural product)
Interaction type: None
Action: None
Ligand approved: no
Primary target: no
Median affinity: 7.139999866485596 pIC50
Reference (Journal): Selective and specific inhibition of the plasmodium falciparum lysyl-tRNA synthetase by the fungal secondary metabolite cladosporin.
Published in: Cell Host Microbe

Ligand: cladosporin (Natural product)
Interaction type: None
Action: None
Ligand approved: no
Primary target: no
Median affinity: 7.099999904632568 pIC50
Reference (Journal): Selective and specific inhibition of the plasmodium falciparum lysyl-tRNA synthetase by the fungal secondary metabolite cladosporin.
Published in: Cell Host Microbe

Ligand: cladosporin (Natural product)
Interaction type: None
Action: None
Ligand approved: no
Primary target: no
Median affinity: 7.059999942779541 pIC50
Reference (Journal): Selective and specific inhibition of the plasmodium falciparum lysyl-tRNA synthetase by the fungal secondary metabolite cladosporin.
Published in: Cell Host Microbe

Ligand: compound 5 [PMID: 30894487] (Synthetic organic)
Interaction type: None
Action: None
Ligand approved: no
Primary target: no
Median affinity: 6.019999980926514 pEC50
Reference (Journal): Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.
Published in: Proc Natl Acad Sci USA

Ligand: compound 5 [PMID: 30894487] (Synthetic organic)
Interaction type: None
Action: None
Ligand approved: no
Primary target: no
Median affinity: 6.570000171661377 pEC50
Reference (Journal): Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.
Published in: Proc Natl Acad Sci USA

Ligand: compound 5 [PMID: 30894487] (Synthetic organic)
Interaction type: None
Action: None
Ligand approved: no
Primary target: no
Median affinity: 6 pEC50
Reference (Journal): Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.
Published in: Proc Natl Acad Sci USA

Ligand: compound 5 [PMID: 30894487] (Synthetic organic)
Interaction type: None
Action: None
Ligand approved: no
Primary target: no
Median affinity: 5 pEC50
Reference (Journal): Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.
Published in: Proc Natl Acad Sci USA

Ligand: compound 5 [PMID: 30894487] (Synthetic organic)
Interaction type: None
Action: None
Ligand approved: no
Primary target: no
Median affinity: 6.409999847412109 pEC50
Reference (Journal): Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.
Published in: Proc Natl Acad Sci USA