Clinical trial NCT02135614
Conditions: Respiratory Syncytial Virus Infection
Sponsor: Gilead Sciences
Start date: 2014-06-09; Completion date: 2017-04-12
Enrollment: 189 participants; Allocation: RANDOMIZED; Intervention model: PARALLEL

Brief summary:
The primary objective of this study is to evaluate the effects of presatovir on respiratory syncytial virus (RSV) viral load in RSV-positive adults who have been hospitalized with acute respiratory infectious symptoms.

Participants will receive 1 dose of presatovir on Day 1 and followed for 27 days postdose. Nasal swabs will be collected at each study visit (excluding Day 28) and assayed for change in viral load as the primary endpoint.

Detailed description:

Arms: arm 1: Participants will receive a single dose of presatovir. arm 2: Participants will receive a single dose of presatovir placebo.
Interventions: intervention 1: Presatovir intervention 2: Presatovir placebo
Intervention descriptions: intervention 1: Presatovir 200 mg (4 x 50 mg tablets) administered orally intervention 2: Presatovir placebo tablets administered orally

Protocol documents:
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