Translating research for human health : major infectious diseases.
Date: 2018-06-29
Institutions: Directorate-General for Research and Innovation
Subjects: EU programme, epidemic, health policy, infectious disease, medical research, public health, research and development, scientific cooperation, sexually transmitted disease, small and medium-sized enterprises

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Translating research 
for human health 
Major  nfectious diseases

i

The activity: ‘Translational research in major infectious diseases: to confront major threats to public health’ is 
divided into four main areas of research: ‘Anti-microbial drug resistance including fungal pathogens’; ‘HIV/AIDS, malaria 
and tuberculosis’; ‘Potentially new and re-emerging epidemics’ and ‘Neglected infectious diseases’.

anti-microbial drug resistance including 
fungal pathogens

The strategic objective of ‘anti-microbial drug resistance’ is to 
confront  the  increasing  emergence  and  spread  of  microbial 
drug resistant pathogens in Europe and the rest of the world 
at  broad  fronts  and  in  a  multidisciplinary  approach  through 
the development of effective infection prevention and control 
strategies.

Topics for second call – Deadline 18 September 2007
• Novel targets for drugs against Gram negative bacteria
Funding scheme: Collaborative Projects  
(small or medium-scale focused research projects with  
maximum contribution of e6.000.000/project)
• Host-pathogen interactions in infections by Streptococcus 

pneumoniae

Funding scheme: Collaborative Projects  
(small or medium-scale focused research projects)
• An integrated platform for development and clinical 

evaluation of point-of-care diagnostic devices for microbial 
detection, antibiotic susceptibility determination and 
biomarkers

Funding scheme: Collaborative Projects  
(large scale Integrating projects)
• Molecular epidemiology to control nosocomial and 

community spreading of highly virulent multi-drug resistant 
strains of bacterial pathogens.

Funding scheme: Collaborative Projects  
(small or medium-scale focused research projects)
• Health and economic cost of antimicrobial resistance
Funding scheme: Coordination and Support action
• Conference on genetic and biochemical tools for post- 
genomic physiological analysis of Staphylococcus, in 
particular MRSA

Funding scheme: Coordination and Support action

conTacT
Anna Lönnroth – Infectious Diseases Unit
Tel: +32 2 2994210 – anna.lonnroth@ec.europa.eu

Cornelius Schmaltz – Infectious Diseases Unit
Tel +32 2 2958984 – cornelius.schmaltz@ec.europa.eu

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HIV/aIDs, malaria and tuberculosis
Under the area ‘HIV/AIDS, malaria and tuberculosis’ research will focus 
on developing new therapies, diagnostic tools, and preventive tools such 
as vaccines and chemicals barriers such as HIV microbicides. Research 
efforts will confront the three diseases at global level, but will also address 
specific European aspects of the three diseases as hepatitis co-infection. 
Preclinical and early clinical research activities will be emphasised. 

Topics for first call – Deadline 19 April 2007
• HIV/AIDS Drug Discovery and Preclinical Development
• Highly Innovative approaches for research into host pathogen 

interaction in tuberculosis

• Development of fast tests for the diagnosis of Multi-Drug Resistant 
strains of HIV, malaria and tuberculosis, and of latent tuberculosis 
infection. 

• Addressing knowledge gaps in pregnancy malaria
Funding scheme: Collaborative Projects (small or medium-scale focused 
research projects)
• Paediatric formulation of drugs against HIV/AIDS, malaria and 

tuberculosis

Funding scheme: Coordination and Support action
• New HIV Vaccines inducing broadly-reactive neutralising antibodies
Funding scheme: Collaborative projects (large scale Integrating projects)

Topics for second call – Deadline 18 September 2007
• Network on HIV and anti HIV drug resistance
Funding scheme: Collaborative projects (large-scale Integrating projects)
• HIV and hepatitis co-infection
Funding scheme: Coordination and Support action
• Blocking the transmission of malaria: the mosquito vector target
Funding scheme: Collaborative Projects (small or medium-scale focused 
research projects)
• European network for study and clinical management of TB drug 

resistance

Funding scheme: Collaborative projects (large-scale Integrating projects)
• Support platform for the development of PRD vaccines
Funding scheme: Coordination and Support action

Topics for specific International cooperation action (sIca) –  
Deadline 18 September 2007
• Highly innovative research in HIV/AIDS, malaria and tuberculosis 

between Indian and European partners

Funding scheme: Collaborative Projects (small or medium-scale focused 
research projects)
• Coordination of European research activities with global initiatives, 

including Public-Private Partnerships

Funding scheme: Coordination and Support action
• Next Generation of researchers for HIV/AIDS, malaria, tuberculosis and 

neglected infectious diseases

Funding scheme: Coordination and Support action

conTacT
Manuel Romaris – Infectious Diseases Unit
Tel +32 2 2998733 – manuel.romaris@ec.europa.eu
Hannu Laang – Infectious Diseases Unit
Tel +32 2 2969602 – hannu.laang@ec.europa.eu

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neglected infectious diseases

Under  the  area  ‘Neglected  infectious  diseases’,  research 
will  focus  on  an  integrated  approach  for  the  development 
of  preventive,  therapeutic  and  control  tools  for  neglected 
infectious  diseases:  diseases  caused  by  Trypanosomatidae 
species  and  a  wider  range  of  vector-borne  diseases,  as  well 
as  other  neglected  infectious  diseases,  including  childhood 
infections.

Topics for specific International cooperation action 
(sIca) – Deadline 18 September 2007
• Development of new tools to control infections due to 

parasites of the Trypanosomatidae family.

• Development of a Leishmania vaccine
• Bio prospecting for drug leads
Funding scheme: Collaborative Projects (small or medium-
scale focused research projects)

conTacT
Ole Olesen – Infectious Diseases Unit
Tel +32 2 2953999 – ole.olesen@ec.europa.eu
Andreas Holtel – Infectious Diseases Unit
Tel +32 2 2953716 – andreas.holtel@ec.europa.eu

potentially new and re-emerging epidemics
The area related to ‘Potentially new and re-emerging epidemics’ 
intends  to  confront  emerging  pathogens  with  pandemic 
potential including zoonoses (e.g. SARS and highly pathogenic 
influenza).  Call  topics  aim  to  cover  the  full’  value  chain’  of 
health research: from innovative basic research to early stage 
clinical  trials  of  new  prevention,  diagnostic  and  therapeutic 
measures all the way to implementation research supporting 
effective public health responses. 

Topics for first call – Deadline 19 April 2007
• Development of broadly protective influenza vaccine 

candidates

Funding scheme: Collaborative Projects (small or medium-
scale focused research with maximum EC contribution of 
e6.000.000/ project)
• Identifying immunological mechanisms of protection for 

influenza vaccines

Funding scheme: Collaborative Projects  
(small or medium-scale focused research projects)
• Standardisation of immunological assays including sur-

rogate markers for evaluation of new influenza vaccines in 
clinical trials

Funding scheme: Coordination and Support action
• Innovative point-of-care diagnostic tests for influenza
• Development of additional treatment strategies for patients 

suffering from highly pathogenic influenza

• Development of pandemic influenza containment and 

mitigation strategies

Funding scheme: Collaborative Projects  
(small or medium-scale focused research projects)
• Supporting highly innovative inter-disciplinary research on 
influenza 
Funding scheme: Collaborative Projects (small or medium-
scale focused research with maximum EC contribution of 
e1.500.000/project)

Topics for specific International cooperation action 
(sIca) – Deadline 19 April 2007
• Influenza research in collaboration with Asian partners
Funding scheme: Collaborative Projects (small or medium-
scale focused research projects)

Topics for second call – Deadline 18 September 2007
• Strengthening  research on prediction, identification, 

modelling and surveillance of newly emerging infectious 
diseases in humans

Funding scheme: Collaborative projects  
(large-scale integrating projects)
• Definition of research needs and priorities in Europe in 

the area of Emerging Infectious Epidemics

Funding scheme: Coordination and Support action

conTacT
Anna Lönnroth – Infectious Diseases Unit
Tel +32 2 2994210 – anna.lonnroth@ec.europa.eu
Cornelius Schmaltz – Infectious Diseases Unit
Tel +32 2 2958984 – cornelius.schmaltz@ec.europa.eu

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