List of the authorised additives in feedingstuffs published in application of Article 9t (b) of Council Directive 70/524/EEC concerning additives in feedingstuffs (Text with EEA relevance)
Date: 2004-02-25
Institutions: European Commission
Subjects: animal nutrition, antibiotic, food additive, food chemistry, medicinal product

25.2.2004

EN

Official Journal of the European Union

C 50/1

I

(Information)

COMMISSION

List of the authorised additives in feedingstuffs (1) published in application of Article 9t (b) of
Council Directive 70/524/EEC concerning additives in feedingstuffs

(2004/C 50/01)

(Text with EEA relevance)

TABLE OF CONTENTS

INTRODUCTION

CHAPTER I: List of additives linked to a person responsible for putting them into circulation and
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
authorised for a period of 10 years

CHAPTER II: List of additives linked to a person responsible for putting them into circulation and authorised
on a provisional basis for no longer than four years or five years in the case of additives which have been the
subject of provisional authorisation before 1 April 1998 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

CHAPTER III: List of other additives authorised for an unlimited period . . . . . . . . . . . . . . . . . . . . . . . . . . .

CHAPTER IV: List of other additives authorised on a provisional basis for no longer than four years or five
years in the case of additives which have been the subject of provisional authorisation before 1 April 1998 . .

ANNEX I: List of the authorised additives belonging to the groups of antibiotics, coccidiostats and growth
promoters in re-evaluation within the scope of Article 9g of Directive 70/524/EEC and included in Annex I
before 1 January 1988 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

ANNEX II: List of the references of the Community Acts having modified the list of the authorised additives
since the 15 November 2001 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

2

3

13

15

57

139

143

(1) Situation as 15 July 2003.

C 50/2

EN

Official Journal of the European Union

25.2.2004

INTRODUCTION

In application of the provisions of Article 9t (b) of Council Directive 70/524/EEC of 23 November 1970
concerning additives in feedingstuffs (1), the Commission publishes each year the list of the authorised
additives in the Official Journal of the European Union C series, subdivided as follows:

— Chapter I: List of additives linked to a person responsible for putting them into circulation and

authorised for a period of 10 years,

— Chapter II: List of additives linked to a person responsible for putting them into circulation and
authorised on a provisional basis for no longer than four years or five years in the case of additives
which have been the subject of provisional authorisation before 1 April 1998,

— Chapter III: List of other additives authorised for an unlimited period,

— Chapter IV: List of other additives authorised on a provisional basis for no longer than four years or
five years in the case of additives which have been the subject of provisional authorisation before
1 April 1998.

Annex I gives the list certain additives belonging to the groups of ‘antibiotics',
‘coccidiostats and other
medicinal substances' and ‘growth promoters' which have been authorised before the 1 January 1988 and
are currently under a re-evaluation period within the scope of Article 9g of Directive 70/524/EEC.

In Annex II, a list gives the references of all the Community Acts having modified the list of the
authorised additives since the 15 November 2001 (2).

(1) OJ L 270, 14.12.1970, p. 1.
(2) List of the authorised additives in feedingstuffs published in application of Article 9t (b) of Council Directive

70/524/EEC concerning additives in feedingstuffs (OJ C 329, 31.12.2002, p. 1).

CHAPTER I: LIST OF ADDITIVES LINKED TO A PERSON RESPONSIBLE FOR PUTTING THEM INTO CIRCULATION AND AUTHORISED FOR A PERIOD OF 10 YEARS

Registration
number of
additive

Name and registration
number of person responsible
for putting additive into
circulation

Antibiotics

Additive
(Trade name)

Composition, chemical formula, description

Species or
category of
animal

Maximum age

Minimum
content

Maximum
content

mg of active substance/kg of
complete feedingstuff

Other provisions

End of period
of
authorisation

E 712

Intervet International bv

Additive composition:

Rabbits

—

2

4

—

30.9.2009

Flavophospholipol
80 g/kg
(Flavomycin 80)

Flavophospholipol
40 g/kg
(Flavomycin 40)

Flavophospholipol: ¯ 80 g activity/kg

Silicon dioxide: 50-150 g/kg

Calcium carbonate: 0-400 g/kg

Flavophospholipol: ¯ 40 g activity/kg

Silicon dioxide: 20-120 g/kg

Calcium carbonate: 200-750 g/kg

Active substance:

Flavophospholipol,

CAS number: 11015-37-5,

(moenomycin A: C69H108N5O34P),

phosphoglycolipid produced by
fermentation of Streptomyces ghanaensis
(DSM 12218).

Composition of antibiotic factors:

Moenomycin A: 40 %-80 %,

Moenomycin A1/2: 0-20 %,

Moenomycin C1: 0-20 %,

Moenomycin C3: 5 %-25 %,

Moenomycin C4: 0-15 %.

.

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2
2
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4

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Registration
number of
additive

Name and registration
number of person responsible
for putting additive into
circulation

Additive
(Trade name)

Composition, chemical formula, description

Species or
category of
animal

Maximum age

Minimum
content

Maximum
content

mg of active substance/kg of
complete feedingstuff

E 716

Intervet International bv

Additive composition:

Piglets

Salinomycin sodium
120 g/kg

(Salocin 120 micro
Granulate)

Salinomycin sodium: ¯ 120 g/kg

Silicon dioxide: 10-100 g/kg

Calcium carbonate: 350-700 g/kg

Four
months

30

60

Pigs for
fattening

Six
months

15

30

Active substance:

Salinomycin sodium,

C42H69O11Na,

CAS number: 53003-10-4,

sodium salt of a polyether
monocarboxylic acid produced by
fermentation of Streptomyces albus
(DSM 12217).

Related impurities:

< 42 mg elaiophylin/kg salinomycin
sodium,

< 40 g 17-epi-20-desoxy-
salinomycin/kg salinomycin sodium.

End of period
of
authorisation

30.9.2009

30.9.2009

Other provisions

Indicate in the
instructions for use:

‘Dangerous for equines'

‘This feedingstuff
contains an ionophore:
simultaneous use with
certain medicinal
substances (e.g. tiamulin)
can be contra-indicated'

Indicate in the
instructions for use:

‘Dangerous for equines'

‘This feedingstuff
contains an ionophore:
simultaneous use with
certain medicinal
substances (e.g. tiamulin)
can be contra-indicated'

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4

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2
2
0
0
4

Registration
number of
additive

Name and registration
number of person responsible
for putting additive into
circulation

Additive
(Trade name)

Composition, chemical formula, description

Species or
category of
animal

Maximum age

Minimum
content

Maximum
content

mg of active substance/kg of
complete feedingstuff

Other provisions

End of period
of
authorisation

E 717

Eli Lilly and Company
Ltd

Additive composition:

Piglets

Four
months

20

40

—

30.9.2009

Avilamycin 200 g/kg

Avilamycin: 200 g activity/kg

(Maxus G200,

Maxus 200)

Soyabean oil or mineral oil: 5-30 g/kg

Soyabean hulls qs 1 kg

Avilamycin 100 g/kg

Avilamycin: 100 g activity/kg

(Maxus G100,

Maxus 100)

Soyabean oil or mineral oil: 5-30 g/kg

Soyabean hulls qs 1 kg

Active substance:

Avilamycin,

C57-62H82-90Cl1-2O31-32,

CAS number of avilamycin A:
69787-79-7, CAS number of
avilamycin B: 73240-30-9,

mixture of oligosaccharides of the
orthosomycin group produced by
Streptomyces viridochromogenes (NRRL
2860), in granular form.

Factor composition:

Avilamycin A: ¯ 60 %.

Avilamycin B: ˜ 18 %.

Avilamycins A+B: ¯ 70 %.

Other single avilamycins: ˜ 6 %.

Pigs for
fattening

Chickens
for fatten-
ing

Turkeys

Six
months

—

—

10

2,5

5

20

10

10

—

—

—

30.9.2009

30.9.2009

20.1.2013

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Registration
number of
additive

Name and registration
number of person responsible
for putting additive into
circulation

Coccidiostats and other medicinal substances

Additive
(Trade name)

Composition, chemical formula, description

Species or
category of
animal

Maximum age

Minimum
content

Maximum
content

mg of active substance/kg of
complete feedingstuff

Other provisions

C

5
0
/
6

End of period
of
authorisation

E 758

Alpharma AS

Additive composition:

Robenidine hydrochlor-
ide 66 g/kg

(Cycostat 66 G)

Robenidine hydrochloride: 66 g/kg

Lignosulfonate: 40 g/kg

Calcium sulfate dihydrate: 894 g/kg

Rabbits for
breeding
purposes

—

50

66

Use prohibited at least
five days before
slaughter

30.9.2009

E
N

Active substance:

Robenidine hydrochloride,

C15H13Cl2N5. HCl,

1,3-bis[(p-chlorobenzylidene)
amino]guanidine hydrochloride,

CAS number: 25875-50-7,

Related impurities:

N,N¡,N¢-Tris[(p-Cl-benzylidene)
amino]guanidine: ˜ 1 %

Bis-[4-Cl-benzylidene]hydrazine: ˜ 1 %

O

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2
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2
2
0
0
4

End of period
of
authorisation

30.9.2009

Registration
number of
additive

Name and registration
number of person responsible
for putting additive into
circulation

Additive
(Trade name)

Composition, chemical formula, description

Species or
category of
animal

Maximum age

Minimum
content

Maximum
content

mg of active substance/kg of
complete feedingstuff

Other provisions

Use prohibited at least
five days before
slaughter

Indicate in the
instructions for use:

‘This feedingstuff
contains an ionophore:
simultaneous use with
certain medicinal
substances can be
contra-indicated'

E 763

Alpharma AS

Additive composition:

Turkeys

12 weeks

90

125

Lasalocid A sodium
15 g/100 g

(Avatec 15 % cc)

Lasalocid A sodium: 15 g/100 g

Corn cob meal: 80,95 g/100 g

Lecithin: 2 g/100 g

Soya oil: 2 g/100 g

Ferric oxide: 0,05 g/100 g

Active substance:

Lasalocid A sodium,

C34H53O8Na,

CAS number: 25999-20-6,

sodium salt of 6-[(3R, 4S, 5S,
7R)-7-[(2S, 3S, 5S)-5-ethyl-5-[(2R, 5R,
6S)-5-ethyl–5-hydroxy-6-methyltet-
rahydro-2H-pyran2-yl]-tetrahydro-
3-methyl-2-furyl]-4-hydroxy-3,5-di-
methyl-6-oxononyl]-2,3-cresotic acid,
produced by Streptomyces lasaliensis
subsp. lasaliensis (ATCC 31180)

Related impurities:

Lasalocid sodium B-E: ˜ 10 %

.

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5
2
2
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4

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Registration
number of
additive

Name and registration
number of person responsible
for putting additive into
circulation

Additive
(Trade name)

Composition, chemical formula, description

Species or
category of
animal

Maximum age

Minimum
content

Maximum
content

mg of active substance/kg of
complete feedingstuff

Other provisions

End of period
of
authorisation

16 weeks

2

3

—

30.9.2009

Chickens
reared for
laying

E 764

Intervet International bv

Additive composition:

Halofuginone hydrobro-
mide 6 g/kg

(Stenorol)

Halofuginone hydrobromide: 6 g/kg

Gelatine: 13,2 g/kg

Starch: 19,2 g/kg

Sugar: 21,6 g/kg

Calcium carbonate: 940 g/kg

Active substance:

Halofuginone hydrobromide,

C16H17BrClN3O3,HBr

DL-trans-7-bromo-6-chloro-3-(3-(3-hy-
droxy-2-piperidyl)acetonyl)-4(3H)-qui-
nazolinone hydrobromide,

CAS number: 64924-67-0.

Related impurities:

Cis-isomer of halofuginone: < 1,5 %

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2
2
0
0
4

Registration
number of
additive

Name and registration
number of person responsible
for putting additive into
circulation

Additive
(Trade name)

Composition, chemical formula, description

E 766

Intervet International bv

Additive composition:

Maximum age

Minimum
content

Maximum
content

mg of active substance/kg of
complete feedingstuff

—

20

25

Species or
category of
animal

Rabbits for
fattening

Salinomycin sodium
120 g/kg

(Sacox 120)

Salinomycin sodium: ¯ 120 g/kg

Silicon dioxide: 10-100 g/kg

Calcium carbonate: 350-700 g/kg

Active substance:

Salinomycin sodium,

C42H69O11Na,

CAS number: 53003-10-4,

sodium salt of a polyether
monocarboxylic acid produced by
fermentation of Streptomyces albus
(DSM 12217)

Related impurities:

< 42 mg elaiophylin/kg salinomycin
sodium,

< 40 g 17-epi-20-desoxy-salinomy-
cin/kg salinomycin sodium,

End of period
of
authorisation

31.5.2011

Other provisions

Use prohibited at least
five days before
slaughter

Indicate in the
instructions for use:

‘Dangerous for equines'

‘This feedingstuff
contains an ionophore:
simultaneous use with
certain medicinal
substances (e.g. tiamulin)
can be contra-indicated'

.

.

2
5
2
2
0
0
4

E
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O

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Registration
number of
additive

Name and registration
number of person responsible
for putting additive into
circulation

Additive
(Trade name)

Composition, chemical formula, description

Species or
category of
animal

Maximum age

Minimum
content

Maximum
content

mg of active substance/kg of
complete feedingstuff

Other provisions

E 770

Alpharma AS

Additive composition:

Maduramicin
ammonium alpha
1 g/100g

(Cygro 1 %)

Maduramicin ammonium alpha:
1 g/100 g

Benzyl alcohol: 5 g/100 g

Corn cob grits qs 100 g

Active substance:

Maduramicin ammonium alpha,

Chickens
for fatten-
ing

—

5

5

C47H83O17N,

Turkeys

16 weeks

5

5

CAS number: 84878-61-5,

ammonium salt of a polyether
monocarboxylic acid produced by
Actinomadura yumaensis (ATCC 31585)
(NRRL 12515).

Related impurities:

Maduramicin ammonium beta: < 10 %

Use prohibited at least
five days before
slaughter

Indicate in the
instructions for use:

‘Dangerous for equines'

‘This feedingstuff
contains an ionophore:
simultaneous use with
certain medicinal
substances (e.g. tiamulin)
can be contra-indicated'

Use prohibited at least
five days before
slaughter

Indicate in the
instructions for use:

‘Dangerous for equines'

‘This feedingstuff
contains an ionophore:
simultaneous use with
certain medicinal
substances (e.g. tiamulin)
can be contra-indicated'

End of period
of
authorisation

30.9.2009

15.12.2011

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Registration
number of
additive

Name and registration
number of person responsible
for putting additive into
circulation

E 771

Janssen Animal Health
B.V.B.A

Other provisions

Use prohibited at least
five days before
slaughter

End of period
of
authorisation

30.9.2009

Use prohibited at least
five days before
slaughter

28.2.2011

—

20.1.2013

Additive
(Trade name)

Composition, chemical formula, description

Species or
category of
animal

Maximum age

Minimum
content

Maximum
content

mg of active substance/kg of
complete feedingstuff

Chickens
for
fattening

—

1

Turkeys for
fattening

12 weeks

16 weeks

Chickens
reared for
laying

1

1

1

1

1

Diclazuril 0,5 g/100 g

(Clinacox 0,5 % Premix)

Diclazuril 0,2 g/100 g

(Clinacox 0,2 % Premix)

Additive composition:

Diclazuril: 0,5 g/100 g
Soybean meal: 99,25 g/100 g
Polyvidone K 30: 0,2 g/100 g
Sodium hydroxyde: 0,0538 g/100 g

Diclazuril: 0,2 g/100 g
Soybean meal: 39,7 g/100 g
Polyvidone K 30: 0,08 g/100 g
Sodium hydroxide: 0,0215 g/100 g
Wheat middlings: 60 g/100 g

Active substance:
Diclazuril,
C17H9Cl3N4O2,
(±)-4-chlorophenyl[2,6-dichloro-
4-(2,3,4,5-tetrahydro-3,5-dioxo-
1,2,4-triazin-2-yl)phenyl]acetonitrile,
CAS number: 101831-37-2,

Related impurities:
Degradation compound (R064318):
˜ 0,2 %
Other related impurities (R066891,
R066896, R068610, R070156,
R068584, R070016): ˜ 0,5 %
individually
Total impurities: ˜ 1,5 %

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Registration
number of
additive

Name and registration
number of person responsible
for putting additive into
circulation

E 772

Eli Lilly and Company
Ltd

Additive
(Trade name)

Composition, chemical formula, description

Species or
category of
animal

Maximum age

Minimum
content

Maximum
content

mg of active substance/kg of
complete feedingstuff

Other provisions

Chickens
for fatten-
ing

—

80

100

Use prohibited at least
five days before
slaughter

Indicate in the
instructions for use:

‘Dangerous for equines'

‘This feedingstuff
contains an ionophore:
simultaneous use with
certain medicinal
substances (e.g. tiamulin)
can be contra-indicated'

Narasin 80 g/kg —
Nicarbazin 80 g/kg

(Maxiban G160)

Additive composition:

Narasin: 80 g activity/kg
Nicarbazin: 80 g/kg
Soyabean oil or mineral oil: 10-30 g/kg
Vermiculite: 0-20 g/kg
Microtracer F-Red: 11 g/kg
Corn cob grits or rice hulls qs 1 kg

Active substance:

(a) Narasin,

C43H72O11,

CAS number: 55134-13-9,

polyether monocarboxylic acid
produced by ‘Streptomyces
aureofaciens' (NRRL 8092), in
granular form,

narasin A activity: ¯ 85 %

(b) C19H18N6O6,

CAS number: 330-95-0,

equimolecular complex of
1,3-bis(4-nitrophenyl) urea and
4,6-dimethylpyrimidin-2-ol, in
granular form

Related impurities:

p-Nitroaniline: ˜ 1 %

End of period
of
authorisation

30.9.2009

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Growth promoters

—

—

—

—

—

—

—

—

—

—

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CHAPTER II: LIST OF ADDITIVES LINKED TO A PERSON RESPONSIBLE FOR PUTTING THEM INTO CIRCULATION AND AUTHORISED ON A PROVISIONAL BASIS FOR NO LONGER

THAN FOUR YEARS OR FIVE YEARS IN THE CASE OF ADDITIVES WHICH HAVE BEEN THE SUBJECT OF PROVISIONAL AUTHORISATION BEFORE 1 APRIL 1998

Regis-
tration
number of
additive

Name and registration
number of person responsible
for putting additive into
circulation

Additive
(Trade name)

Composition, chemical formula, description

Species or
category of
animal

Minimum
content

Maximum
content

Maximum age

Other provisions

mg of active substance/kg of
complete feedingstuff

End of period of
authorisation

—

—

prohibited

at
five days before

Use
least
slaughter

1.6.2006 (v)

Antibiotics

—

—

—

—

—

Coccidiostats and other medicinal substances

29

Phibro Animal
Health, s.p.r.l.

Semduramicin sodium
(Aviax 5 %)

Additive composition:

Semduramicin sodium: 51,3 g/kg

Chickens
for fatten-
ing

—

—

—

20

—

25

Sodium carbonate: 40 g/kg

Mineral oil: 50 g/kg

Sodium aluminosilicate: 20 g/kg

Soybean mill run: 838,7 g/kg

Active substance:

Semduramicin sodium

C45H76O16Na

CAS number 113378-31-7

sodium salt of a monocarboxylic acid
polyether ionophore produced by
Actinomadura roseorufa (ATCC 53664)

Related impurities:

Descarboxylsemduramicin, ˜ 2 %

Desmethoxylsemduramicin, ˜ 2 %

Hydroxysemduramicin, ˜ 2 %

Total: ˜ 5 %

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/
1
3

Regis-
tration
number of
additive

Name and registration
number of person responsible
for putting additive into
circulation

Growth promoters

1

BASF Aktiengesellschaft
α DE RP 1 31401

Additive
(Trade name)

Composition, chemical formula, description

Species or
category of
animal

Minimum
content

Maximum
content

Maximum age

Other provisions

mg of active substance/kg of
complete feedingstuff

End of period of
authorisation

Potassium diformate
(FormiTM LHS)

Additive composition:

Potassium diformate, solid min. 98 %,

Piglets
(weaned)

2 months

6 000

18 000

—

30.6.2005 (s)

Silicate max. 1,5 %,

Water max. 0,5 %

Active substance:

Potassium diformate, solid

KH(COOH)2

CAS No 20642-05-1

Pigs for
fattening

—

6 000

12 000

—

30.6.2005 (s)

C

5
0
/
1
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

CHAPTER III: LIST OF OTHER ADDITIVES AUTHORISED FOR AN UNLIMITED PERIOD

EC No

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

mg/kg of complete feedingstuff

Other provisions

End of period of
authorisation

.

.

2
5
2
2
0
0
4

Antioxidant substances

E 300

L-Ascorbic acid

C6H8O6

E 301

Sodium L-ascorbate

C6H7O6Na

E 302

Calcium L-ascorbate

C12H14O12Ca · 2H2O

E 303

5,6-Diacetyl-L-ascorbic acid

C10H12O8

E 304

6-Palmityl-L-ascorbic acid

C22H38O7

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

E 306

Tocopherol-rich extracts of
natural origin

—

All species or categories of
animals

E 307

Synthetic alpha-tocopherol

C29H50O2

E 308

Synthetic gamma-tocopherol

C28H48O2

E 309

Synthetic delta-tocopherol

C27H46O2

E 310

Propyl gallate

C10H12O5

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

E 311

Octyl gallate

C15H22O5

All species or categories of
animals

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

—

—

—

—

—

—

—

—

—

100 alone or
together with
E 311 or
E 312

100 alone or
together with
E 310 or
E 312

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
1
5

EC No

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

mg/kg of complete feedingstuff

Other provisions

End of period of
authorisation

E 312

Dodecyl gallate

C19H30O5

All species or categories of
animals

—

—

E 320

Butylated hydroxyanisole
(BHA)

C11H16O2

All species or categories of
animals except dogs

—

—

Dogs

—

—

E 321

Butylated hydroxytoluene
(BHT)

C15H24O

All species or categories of
animals except dogs

—

—

Dogs

—

—

E 324

Ethoxyquin

C14H19ON

All species or categories of
animals except dogs

—

—

100 alone or
together with
E 310 or
E 311

150 alone or
together with
E 321 and/or
E 324

150 alone or
together with
E 321

150 alone or
together with
E 320 and/or
E 324

150 alone or
together with
E 320

All feedingstuffs

All feedingstuffs

The mixture of ethoxyquin with
BHA and/or BHT is allowed
provided the total concentration
of the mixture does not exceed
150 mg/kg of complete
feedingstuff.

All feedingstuffs

The mixture of ethoxyquin with
BHA and/or BHT is allowed
provided the total concentration
of the mixture does not exceed
150 mg/kg of complete
feedingstuff.

All feedingstuffs

150 alone or
together with
E 320 and/or
E 321

Dogs

—

—

100

The mixture of ethoxyquin with
BHA and/or BHT is allowed
provided the total concentration
of the mixture does not exceed
150 mg/kg of complete
feedingstuff.

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

C

5
0
/
1
6

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

EC No

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

mg/kg of complete feedingstuff

Other provisions

End of period of
authorisation

.

.

2
5
2
2
0
0
4

—

All species or categories of
animals

—

—

—

Flavouring and appetising substances

1. All natural products and
corresponding synthetic
products

2. Artificial substances:

E 954 (i)

Saccharin

C7H5NO3S

E 954 (ii)

Calcium saccharin

C7H3NCaO3S

E 954 (iii)

Sodium saccharin

C7H4NNaO3S

E 959

Neohesperidine dihydrochal-
cone

C28H36O15

Piglets

Piglets

Piglets

Piglets

Dogs

Calves

Ovines

Emulsifying and stabilising agents, thickeners and gelling agents

E 322

Lecithins

E 400

Alginic acid

E 401

Sodium alginate

—

—

—

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

—

—

—

—

—

—

—

—

All feedingstuffs

All feedingstuffs

All feedingstuffs

Without a
time limit

E
N

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
1
7

Four months

Four months

Four months

Four months

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

150

150

150

35

35

30

30

—

—

—

EC No

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

mg/kg of complete feedingstuff

Other provisions

End of period of
authorisation

E 402

Potassium alginate

E 403

Ammonium alginate

E 404

Calcium alginate

E 405

Propane-1,2-diol alginate
(Propyleneglycol alginate)

E 406

Agar

E 407

Carrageenan

E 410

Locust bean gum (Carob
gum)

E 411

Tamarind seed flour

E 412

Guar gum

E 413

Tragacanth

E 414

Acacia (Gum arabic)

E 415

Xanthan gum

E 418

Gellan gum

—

—

—

—

—

—

—

—

—

—

—

—

All species or categories of
animals

All species or categories of
animals with the exception
of aquarium fish

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

Polytetrasaccharide contain-
ing glucose, glucuronic acid
and rhamnose (2:1:1)
produced by Pseudomonas
elodea (ATCC 31466)

Dogs

Cats

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Feedingstuffs with a moisture
content exceeding 20 %

Without a
time limit

Feedingstuffs with a moisture
content exceeding 20 %

Without a
time limit

C

5
0
/
1
8

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

EC No

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

mg/kg of complete feedingstuff

Other provisions

End of period of
authorisation

.

.

2
5
2
2
0
0
4

E 420

Sorbitol

E 421

Mannitol

E 422

Glycerol

E 432

Polyoxyethylene (20)-sorbitan
monolaurate

E 433

Polyoxyethylene (20)-sorbitan
monooleate

E 434

Polyoxyethylene (20)-sorbitan
monopalmitate

E 435

Polyoxyethylene (20)-sorbitan
monostearate

E 436

Polyoxyethylene (20)-sorbitan
tristearate

E 440

Pectins

E 450b (i)

Pentasodium triphosphate

—

—

—

—

—

—

—

—

—

—

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

Dogs

Cats

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

All feedingstuffs

All feedingstuffs

All feedingstuffs

Milk replacers only

Milk replacers only

Milk replacers only

Milk replacers only

Milk replacers only

5 000 (alone
or with the
other poly-
sorbates)

5 000 (alone
or with the
other poly-
sorbates)

5 000 (alone
or with the
other poly-
sorbates)

5 000 (alone
or with the
other poly-
sorbates)

5 000 (alone
or with the
other poly-
sorbates)

—

All feedingstuffs

5 000

All feedingstuffs

5 000

All feedingstuffs

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
1
9

EC No

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

mg/kg of complete feedingstuff

Other provisions

End of period of
authorisation

E 460

Microcrystalline cellulose

E 460 (ii)

Cellulose powder

E 461

Methylcellulose

E 462

Ethylcellulose

E 463

Hydroxypropylcellulose

E 464

Hydroxypropylmethylcellu-
lose

E 465

Ethylmethylcellulose

E 466

E 470

Carboxymethylcellulose
(Sodium salt of
carboxymethyl ether of
cellulose)

Sodium, potassium and
calcium salts of edible fatty
acids, alone or in mixtures,
derived either from edible
fats or from distilled edible
fatty acids

E 471

Mono- and di-glycerides of
fatty acids

—

—

—

—

—

—

—

—

—

—

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

All feedingstuffs

—

All feedingstuffs

—

All feedingstuffs

—

All feedingstuffs

—

All feedingstuffs

—

All feedingstuffs

—

All feedingstuffs

—

All feedingstuffs

All species or categories of
animals

—

—

—

All feedingstuffs

All species or categories of
animals

—

—

—

All feedingstuffs

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

C

5
0
/
2
0

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

EC No

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

mg/kg of complete feedingstuff

Other provisions

End of period of
authorisation

.

.

2
5
2
2
0
0
4

E 472

Mono- and di-glycerides of
edible fatty acids esterified
with the following acids:

(a) acetic;

(b)

lactic;

(c) citric;

(d)

tartaric;

(e) mono- and

diacetyltartaric

Sucrose esters of fatty acids
(esters of saccharose and
edible fatty acids)

Sucroglycerides (mixture of
esters of saccharose and
mono- and di-glycerides of
edible fatty acids)

Polyglycerol esters of
non-polymerised edible fatty
acids

Mono-esters of
propane-1,2-diol (propyle-
neglycol) and edible fatty
acids, alone or in mixtures
with diesters

E 473

E 474

E 475

E 477

E 480

Stearoyl 2-lactylic acid

E 481

Sodium stearoyl 2-lactylate

E 482

Calcium stearoyl 2-lactylate

E 483

Stearyl tartrate

—

—

—

—

—

—

—

—

—

All species or categories of
animals

—

—

—

All feedingstuffs

Without a
time limit

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

All feedingstuffs

—

All feedingstuffs

—

All feedingstuffs

—

All feedingstuffs

—

—

—

—

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
2
1

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

EC No

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

mg/kg of complete feedingstuff

Other provisions

End of period of
authorisation

E 484

Glyceryl polyethyleneglycol
ricinoleate

E 486

Dextrans

E 487

E 488

E 489

Polyethyleneglycol ester of
fatty acids from soya oil

Polyoxyethylated glyceride of
tallow fatty acids

Ether of polyglycerol and of
alcohols obtained by the
reduction of oleic and
palmitic acids

E 490

Propane-1,2-diol

—

—

—

—

—

—

All species or categories of
animals

All species or categories of
animals

Calves

Calves

Calves

Dairy cows

Cattle for fattening

Calves

Lambs

Kids

Pigs

Poultry

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

All feedingstuffs

—

All feedingstuffs

6 000

Milk replacers only

5 000

Milk replacers only

5 000

Milk replacers only

12 000

All feedingstuffs

36 000

All feedingstuffs

36 000

All feedingstuffs

36 000

All feedingstuffs

36 000

All feedingstuffs

36 000

All feedingstuffs

36 000

All feedingstuffs

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

C

5
0
/
2
2

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

EC No

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

mg/kg of complete feedingstuff

Other provisions

End of period of
authorisation

.

.

2
5
2
2
0
0
4

E 491

Sorbitan monostearate

E 492

Sorbitan tristearate

E 493

Sorbitan monolaurate

E 494

Sorbitan monooleate

E 495

Sorbitan monopalmitate

E 496

Polyethyleneglycol 6 000

E 497

E 498

Polyoxypropylene-polyoxy-
ethylene polymers (M.W.
6 800-9 000)

Partial polyglycerol esters of
polycondensed fatty acids of
castor oil

E 499

Cassia gum

—

—

—

—

—

—

—

—

—

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

Dogs

Dogs

Cats

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

All feedingstuffs

—

All feedingstuffs

—

All feedingstuffs

—

All feedingstuffs

—

All feedingstuffs

300

All feedingstuffs

50

All feedingstuffs

—

All feedingstuffs

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

17 600

Feedingstuffs with a moisture
content exceeding 20 %

Without a
time limit

17 600

Feedingstuffs with a moisture
content exceeding 20 %

Without a
time limit

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
2
3

EC No

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

mg/kg of complete feedingstuff

Other provisions

End of period of
authorisation

Colourants, including pigments

1. Carotenoids and xanthophylls

E 160c

Capsanthin

C40H56O3

Poultry

—

—

E 160e

Beta-apo-8¡-carotenal

C30H40O

Poultry

—

—

E 160f

Ethyl ester of
beta-apo-8¡-carotenoic acid

C32H44O2

Poultry

—

—

E 161b

Lutein

C40H56O2

Poultry

—

—

E 161c

Cryptoxanthin

C40H56O

Poultry

—

—

80 (alone or
with the
other carote-
noids and
xanthophylls)

80 (alone or
with the
other carote-
noids and
xanthophylls)

80 (alone or
with the
other carote-
noids and
xanthophylls)

80 (alone or
with the
other carote-
noids and
xanthophylls)

80 (alone or
with the
other carote-
noids and
xanthophylls)

—

—

—

—

—

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

C

5
0
/
2
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

EC No

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

mg/kg of complete feedingstuff

Other provisions

End of period of
authorisation

.

.

2
5
2
2
0
0
4

E 161g

Canthaxanthin

C40H52O2

Poultry other than laying
hens

—

—

25

Laying hens

—

—

8

Salmon, trout

—

—

25

The mixture of canthaxanthin
with other carotenoids and
xanthophylls is allowed provided
that the total concentration of the
mixture does not exceed 80 mg/kg
in the complete feedingstuff.

The mixture of canthaxanthin
with other carotenoids and
xanthophylls is allowed provided
that the total concentration of the
mixture does not exceed 80 mg/kg
in the complete feedingstuff.

Use permitted from the age of
six months onwards.
The mixture of canthaxanthin
with astaxanthin is allowed
provided that the total
concentration of the mixture
does not exceed 100 mg/kg in
the complete feedingstuff.

E 161h

Zeaxanthin

C40H56O2

Poultry

Dogs, cats and ornamental
fish

E 161i

Citranaxanthin

C33H44O

Laying hens

E 161j

Astaxanthin

C40H52O4

Salmon, trout

—

—

—

—

—

—

—

—

80 (alone or
with the
other carote-
noids and
xanthophylls)

80 (alone or
with the
other carote-
noids and
xanthophylls)

—

—

—

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

—

100

Use only permitted from the age
of six months onwards.

Without a
time limit

The mixture of astaxanthin with
canthaxanthin is allowed
provided that the total
concentration of the mixture
does not exceed 100 mg/kg in
the complete feedingstuff.

Ornamental fish

—

—

—

—

Without a
time limit

C

5
0
/
2
5

EC No

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

mg/kg of complete feedingstuff

Other provisions

End of period of
authorisation

2. Other colourants

E 102

Tartrazine

C16H9N4O9S2Na3

Ornamental fish

E 110

Sunset yellow FCF

C16H10N2O7S2Na2

Ornamental fish

E 124

Ponceau 4 R

C20H11N2O10S3Na3

Ornamental fish

E 127

Erythrosine

C20H6I4O5Na2 H2O

Ornamental fish

E 131

Patent blue V

Calcium salt of the
disulphonic acid of
m-hydroxytetraethyldiamino
triphenylcarbinol anhydride

All species or categories of
animals with the exception
of dogs and cats

Dogs

Cats

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Permitted in animal feedingstuffs
only in products processed from:

Without a
time limit

(i) waste products of foodstuffs,

(ii) denatured cereals or manioc

flour, or

(iii) other base substances

denatured by means of these
agents or coloured during
technical preparation to
ensure the necessary
identification during
manufacture.

—

—

Without a
time limit

Without a
time limit

C

5
0
/
2
6

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

EC No

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

mg/kg of complete feedingstuff

Other provisions

End of period of
authorisation

.

.

2
5
2
2
0
0
4

E 132

Indigotine

C16H8N2O8S2Na2

Ornamental fish

E 141

Chlorophyll copper complex

—

Ornamental fish

E 142

Acid brilliant green BS
(Lissamine green)

Sodium salt of
4,4'-bis(dimethylamino) dip-
henylmethylene-2-naphtol-
3,6-disulphonic acid

All species or categories of
animals with the exception
of dogs, cats and ornamental
fish

Dogs

Cats

Ornamental fish

E 153

Carbon black

C

Ornamental fish

E 160b

Bixin

C25H30O4

Ornamental fish

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

Without a
time limit

Without a
time limit

Permitted in animal feedingstuffs
only in products processed from:

Without a
time limit

(i) waste products of foodstuffs,

(ii) denatured cereals or manioc

flour, or

(iii) other base substances

denatured by means of these
agents or coloured during
technical preparation to
ensure the necessary
identification during
manufacture.

—

—

—

—

—

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
2
7

EC No

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

mg/kg of complete feedingstuff

Other provisions

End of period of
authorisation

E 172

Iron oxide, red

Fe2O3

Ornamental fish

3. Colouring agents

—

authorised for colouring
foodstuffs by Community
rules, other than Patent
blue V, Acid brilliant
green BS, and
Canthaxanthin

All species or categories of
animals with the exception
of dogs and cats

Dogs

Cats

3.1 Canthaxanthin

authorised for colouring
foodstuffs by
Community rules

—

All species or categories of
animals other than poultry,
salmon, trout, dogs and cats

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

Without a
time limit

Permitted in animal feedingstuffs
only in products processed from:

Without a
time limit

(i) waste products of foodstuffs,

or

(ii) other base substances, with
the exception of cereals and
manioc flour, denatured by
means of these agents or
coloured during technical
preparation to ensure the
necessary identification
during manufacture.

—

—

Without a
time limit

Without a
time limit

Permitted in animal feedingstuffs
only in products processed from:

Without a
time limit

(i) waste products of foodstuffs,

or

(ii) other base substances, with
the exception of cereals and
manioc flour, denatured by
means of these agents or
coloured during technical
preparation to ensure the
necessary identification
during manufacture.

C

5
0
/
2
8

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

Dogs

—

—

—

—

Without a
time limit

.

.

2
5
2
2
0
0
4

EC No

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

mg/kg of complete feedingstuff

Other provisions

End of period of
authorisation

Cats

Poultry other than laying
hens, salmon, trout,

—

—

—

—

—

25

—

Without a
time limit

Permitted in animal feedingstuffs
only in products processed from:

Without a
time limit

(i) waste products of foodstuffs,

or

(ii) other base substances, with
the exception of cereals and
manioc flour, denatured by
means of these agents or
coloured during technical
preparation to ensure the
necessary identification
during manufacture.

Laying hens

—

—

8

Permitted in animal feedingstuffs
only in products processed from:

Without a
time limit

(i) waste products of foodstuffs,

or

(ii) other base substances, with
the exception of cereals and
manioc flour, denatured by
means of these agents or
coloured during technical
preparation to ensure the
necessary identification
during manufacture.

Preservatives

E 200

Sorbic acid

C6H8O2

E 201

Sodium sorbate

C6H7O2Na

E 202

Potassium sorbate

C6H7O2K

E 203

Calcium sorbate

C12H14O4Ca

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

—

—

—

—

—

—

—

—

—

—

—

—

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
2
9

EC No

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

mg/kg of complete feedingstuff

Other provisions

End of period of
authorisation

E 214

Ethyl 4-hydroxybenzoate

C9H10O3

E 215

Sodium ethyl
4-hydroxybenzoate

C9H9O3Na

E 216

Propyl 4-hydroxybenzoate

C10H12O3

E 217

Sodium propyl
4-hydroxybenzoate

C10H11O3Na

E 218

Methyl 4-hydroxybenzoate

C8H8O3

E 219

Sodium methyl
4-hydroxybenzoate

C8H7O3Na

Pets

Pets

Pets

Pets

Pets

Pets

E 222

Sodium bisulphite

NaHSO3

Dogs

—

—

—

—

—

—

—

—

—

—

—

—

—

—

Cats

—

—

E 223

Sodium metabisulphite

Na2S2O5

Dogs

—

—

Cats

—

—

—

—

—

—

—

—

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

All feedingstuffs except
unprocessed meat and fish

Without a
time limit

All feedingstuffs except
unprocessed meat and fish

Without a
time limit

All feedingstuffs except
unprocessed meat and fish

Without a
time limit

All feedingstuffs except
unprocessed meat and fish

Without a
time limit

Separately or
together with
E 223: 500
expressed as
SO2

Separately or
together with
E 223: 500
expressed as
SO2

Separately or
together with
E 222: 500
expressed as
SO2

Separately or
together with
E 222: 500
expressed as
SO2

C

5
0
/
3
0

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

EC No

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

mg/kg of complete feedingstuff

Other provisions

End of period of
authorisation

E 236

Formic acid

CH2O2

All species or categories of
animals

—

—

—

Instructions for use must include
the following:

Without a
time limit

.

.

2
5
2
2
0
0
4

E 237

Sodium formate

CHO2Na

E 238

Calcium formate

C2H2O4Ca

All species or categories of
animals

All species or categories of
animals

—

—

E 240

Formaldehyde

CH2O

Pigs

Six months

E 250

Sodium nitrite

NaNO2

E 260

Acetic acid

C2H4O2

E 261

Potassium acetate

C2H3O2K

E 262

Sodium diacetate

C4H7O4Na

All species or categories of
animals

Dogs

Cats

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

—

—

—

—

—

—

‘Formic acid must not be used,
either alone or as a mixture with
other acids where it forms more
than 50 % by weight of the
mixture, for the aerobic acid
preservation of unprocessed
cereals having a moisture
content in excess of 15 %'.

—

All feedingstuffs

—

All feedingstuffs

—

Skimmed milk only:

maximum content: 600 mg/kg

—

For silage only

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

100

100

Feedingstuffs with a moisture
content exceeding 20 %

Without a
time limit

Feedingstuffs with a moisture
content exceeding 20 %

Without a
time limit

—

All feedingstuffs

—

All feedingstuffs

—

All feedingstuffs

Without a
time limit

Without a
time limit

Without a
time limit

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
3
1

—

—

—

—

—

—

—

—

—

EC No

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

mg/kg of complete feedingstuff

Other provisions

End of period of
authorisation

E 263

Calcium acetate

C4H6O4Ca

E 270

Lactic acid

E 280

Propionic acid

C3H6O3

C3H6O2

E 281

Sodium propionate

C3H5O2Na

E 282

Calcium propionate

C6H10O4Ca

E 283

Potassium propionate

C3H5O2K

E 284

Ammonium propionate

C3H9O2N

E 285

Methylpropionic acid

C4H8O2

E 295

Ammonium formate

CH5O2N

E 296

DL-Malic acid

E 297

Fumaric acid

C4H6O5

C4H4O4

E 325

Sodium lactate

C3H5O3Na

E 326

Potassium lactate

C3H5O3K

E 327

Calcium lactate

C6H10O6Ca

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

Ruminants, at the beginning
of rumination

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

1 000

4 000

—

—

—

—

—

—

—

—

—

—

—

—

—

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

C

5
0
/
3
2

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

EC No

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

mg/kg of complete feedingstuff

Other provisions

End of period of
authorisation

.

.

2
5
2
2
0
0
4

E 330

Citric acid

C6H8O7

E 331

Sodium citrates

E 332

Potassium citrates

E 333

Calcium citrates

E 334

L-tartaric acid

C4H6O6

E 335

Sodium L-tartrates

E 336

Potassium L-tartrates

—

—

—

—

—

E 337

Potassium sodium L-tartrate

C4H4O6KNa . 4H2O

E 338

Orthophosphoric acid

H3PO4

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

All species or categories of
animals

E 490

Propane-1,2-diol

C3H8O2

Dogs

E 507

Hydrochloric acid

HCl

E 513

Sulphuric acid

H2SO4

All species or categories of
animals

All species or categories of
animals

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

All feedingstuffs

53 000

All feedingstuffs

—

—

For silage only

For silage only

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
3
3

EC No

Additive

Chemical formula,
description

Species or category of animal

Maximum age

Maximum content
in/kg of complete
feedingstuff or of
the daily ration

Other provisions

End of period of authorisation

Vitamins, provitamins and chemically well-defined substances having similar effect

E 672

1. Vitamin A

—

Chickens for fattening

Ducks for fattening

Turkeys for fattening

Lambs for fattening

Pigs for fattening

Bovines for fattening

Calves for fattening

Others species or categories of
animals

2. Vitamin D

E 670

Vitamin D2

—

Pigs

Piglets

Bovines

Ovines

—

—

—

—

—

—

—

—

—

—

—

—

13 500

13 500

13 500

13 500

13 500

13 500

All feedingstuffs except
feedingstuffs for young animals

Without a time limit

All feedingstuffs except
feedingstuffs for young animals

Without a time limit

All feedingstuffs except
feedingstuffs for young animals

Without a time limit

All feedingstuffs except
feedingstuffs for young animals

Without a time limit

All feedingstuffs except
feedingstuffs for young animals

Without a time limit

All feedingstuffs except
feedingstuffs for young animals

Without a time limit

25 000

Milk replacers only

Without a time limit

—

All feedingstuffs

Without a time limit

2 000

Simultaneous use of vitamin D3
prohibited

Without a time limit

10 000

Milk replacers only.

Without a time limit

Simultaneous use of vitamin D3
prohibited

4 000

4 000

Simultaneous use of vitamin D3
prohibited

Without a time limit

Simultaneous use of vitamin D3
prohibited

Without a time limit

C

5
0
/
3
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

EC No

Additive

Chemical formula,
description

Species or category of animal

Maximum age

Maximum content
in/kg of complete
feedingstuff or of
the daily ration

Other provisions

End of period of authorisation

.

.

2
5
2
2
0
0
4

Calves

Equines

Other species or categories of
animals with the exception of
poultry and fish

E 671

Vitamin D3

—

Pigs

Piglets

Bovines

Ovines

Calves

Equines

Chickens for fattening

Turkeys

—

—

—

—

—

—

—

—

—

—

—

10 000

Milk replacers only.

Without a time limit

Simultaneous use of vitamin D3
prohibited

4 000

2 000

Simultaneous use of vitamin D3
prohibited

Without a time limit

Simultaneous use of vitamin D3
prohibited

Without a time limit

2 000

Simultaneous use of vitamin D2
prohibited

Without a time limit

10 000

Milk replacers only.

Without a time limit

Simultaneous use of vitamin D2
prohibited

4 000

4 000

Simultaneous use of vitamin D2
prohibited

Without a time limit

Simultaneous use of vitamin D2
prohibited

Without a time limit

10 000

Milk replacers only.

Without a time limit

Simultaneous use of vitamin D2
prohibited

4 000

5 000

5 000

Simultaneous use of vitamin D2
prohibited

Without a time limit

Simultaneous use of vitamin D2
prohibited

Without a time limit

Simultaneous use of vitamin D2
prohibited

Without a time limit

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
3
5

EC No

Additive

Chemical formula,
description

Species or category of animal

Maximum age

Other poultry

Fish

Other species or categories of
animals

3. All subtances in the group
except vitamins A and D

—

All species or categories of
animals

—

—

—

—

Maximum content
in/kg of complete
feedingstuff or of
the daily ration

3 000

3 000

2 000

Other provisions

End of period of authorisation

Simultaneous use of vitamin D2
prohibited

Without a time limit

Simultaneous use of vitamin D2
prohibited

Without a time limit

Simultaneous use of vitamin D2
prohibited

Without a time limit

—

All feedingstuffs

Without a time limit

EC No

Element

Additive

Chemical formula

Maximum content of the element in mg/kg of
complete feedingstuff

Other provisions

End of period of
authorisation

Trace elements

E 1

Iron — Fe

Ferrous carbonate

FeCO3

1 250 (total)

Ferrous chloride,
tetrahydrate

Ferric chloride,
hexahydrate

Ferrous citrate,
hexahydrate

FeCl2 . 4H2O

1 250 (total)

FeCl3 . 6H2O

1 250 (total)

Fe3(C6H5O7)2 . 6H2O

1 250 (total)

Ferrous fumarate

FeC4H2O4

1 250 (total)

Ferrous lactate,
trihydrate

Fe(C3H5O3)2 . 3H2O

1 250 (total)

Ferric oxide

Fe2O3

1 250 (total)

—

—

—

—

—

—

—

Without a time limit

Without a time limit

Without a time limit

Without a time limit

Without a time limit

Without a time limit

Without a time limit

C

5
0
/
3
6

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

EC No

Element

Additive

Chemical formula

Maximum content of the element in mg/kg of
complete feedingstuff

Other provisions

Ferrous sulphate,
monohydrate

FeSO4H2O

1 250 (total)

Permitted:

End of period of
authorisation

Without a time limit

(i)

in denatured skimmed-milk powder and
in compound feedingstuffs manufactured
from denatured skimmed-milk powder:

— subject to the mandatory provisions
of Commission Regulations (EEC)
No 368/77 and (EEC) No 443/77,

— declaration of the amount of iron
added, expressed as the element, on
the label or package or container
of
skimmed-milk
powder;

denatured

(ii)

in compound feedingstuffs other than
those listed under (i).

Ferrous sulphate,
heptahydrate

FeSO4 . 7H2O

1 250 (total)

Permitted:

Without a time limit

(i)

in denatured skimmed-milk powder and
in compound feedingstuffs manufactured
from denatured skimmed-milk powder:

— subject to the mandatory provisions
of Commission Regulations (EEC)
No 368/77 and (EEC) No 443/77,

— declaration of the amount of iron
added, expressed as the element, on
the label or package or container
of
skimmed-milk
powder;

denatured

(ii)

in compound feedingstuffs other than
those listed under (i).

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
3
7

EC No

Element

Additive

Chemical formula

Maximum content of the element in mg/kg of
complete feedingstuff

Other provisions

Ferrous chelate of
amino acids, hydrate

Fe(x)1-3 . nH2O

1 250 (total)

E 2

Iodine — I

Calcium iodate,
hexahydrate

(x=anion of any amino
acid derived from
hydrolysed soya protein)

Molecular weight not
exceeding 1 500

Ca(IO3)2 . 6H2O

Equines: 4 (total)

Fish: 20 (total)

species or categories of animals:

Other
10 (total)

Calcium iodate,
anhydrous

Ca(IO3)2

Equines: 4 (total)

Fish: 20 (total)

Sodium iodide

Nal

Potassium iodide

KI

species or categories of animals:

Other
10 (total)

Equines: 4 (total)

Fish: 20 (total)

species or categories of animals:

Other
10 (total)

Equines: 4 (total)

Fish: 20 (total)

species or categories of animals:

Other
10 (total)

E 3

Cobalt — Co

Cobaltous acetate,
tetrahydrate

Basic cobaltous
carbonate, monohy-
drate

Cobaltous chloride,
hexahydrate

Cobaltous sulphate,
heptahydrate

Cobaltous sulphate,
monohydrate

Cobaltous nitrate,
hexahydrate

Co(CH3COO)2 . 4H2O

10 (total)

2CoCO3 . 3Co(OH)2 . H2O 10 (total)

CoCl2 . 6H2O

10 (total)

CoSO4 . 7H2O

10 (total)

CoSO4 . H2O

10 (total)

CO(NO3)2 . 6H2O

10 (total)

—

—

—

—

—

—

—

—

—

—

—

End of period of
authorisation

Without a time limit

Without a time limit

Without a time limit

Without a time limit

Without a time limit

Without a time limit

Without a time limit

Without a time limit

Without a time limit

Without a time limit

Without a time limit

C

5
0
/
3
8

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

EC No

Element

Additive

Chemical formula

Maximum content of the element in mg/kg of
complete feedingstuff

Other provisions

End of period of
authorisation

.

.

2
5
2
2
0
0
4

E 4

Copper — Cu

Cupric acetate,
monohydrate

Cu(CH3COO)2 . H2O

Pigs for fattening:

Basic cupric
carbonate, monohy-
drate

CuCO3 · Cu(OH)2 . H2O

Cupric chloride,
dihydrate

CuCl2 . 2H2O

Cupric methionate

Cu(C5H10NO2S)2

Cupric oxide

CuO

Cupric sulphate,
pentahydrate

CuSO4 . 5H2O

— in Member States where the mean
density of
the porcine population is
equal to or higher than 175 pigs per
100 ha of utilisable agricultural land:

— up to 16 weeks: 175 (total),

— from 17th week up to slaughter:

35 (total),

— in Member States where the mean
density of
the porcine population is
lower than 175 pigs per 100 ha of
utilisable agricultural land:

— up to 16 weeks: 175 (total),

— from 17th week up to six months:

100 (total),

— over six months up to slaughter:

35 (total).

Breeding pigs: 35 (total)

Calves:

— milk replacers 30 (total),

— other complete feedingstuffs: 50 (total).

Ovines: 15 (total)

species or categories of animals:

Other
35 (total).

—

—

—

—

—

—

Without a time limit

Without a time limit

Without a time limit

Without a time limit

Without a time limit

Without a time limit

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
3
9

EC No

Element

Additive

Chemical formula

Maximum content of the element in mg/kg of
complete feedingstuff

Other provisions

End of period of
authorisation

Denatured skimmed milk powder and
compound feedingstuffs manufactured from
denatured skimmed milk powder:

Without a time limit

— subject

to the relevant provisions of
(EEC) No

Commission Regulations
368/77 and (EEC) No 443/77,

— declaration of

the amount of copper
added, expressed as the element, on the
container of
label or package or
denatured skimmed milk powder.

Cupric sulphate,
monohydrate

CuSO4 . H2O

Pigs for fattening:

Cupric sulphate,
pentahydrate

CuSO4 . 5H2O

— in Member States where the mean
the porcine population is
density of
equal to or higher than 175 pigs per
100 ha of utilisable agricultural land:

— up to 16 weeks: 175 (total),

— from 17th week up to slaughter:

35 (total).

— in Member States where the mean
the porcine population is
density of
lower than 175 pigs per 100 ha of
utilisable agricultural land:

— up to 16 weeks: 175 (total),

— from 17th week up to six months:

100 (total),

— over six months up to slaughter:

35 (total).

Breeding pigs: 35 (total).

Ovines: 15 (total).

Other species or categories of animals with
the exception of calves: 35 (total).

C

5
0
/
4
0

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

End of period of
authorisation

Without a time limit

EC No

Element

Additive

Chemical formula

Maximum content of the element in mg/kg of
complete feedingstuff

Other provisions

Cupric chelate of
amino acids hydrate

Cu (x)1-3 . nH2O
(x=anion of any amino
acid derived from
hydrolysed soya protein)

Molecular weight not
exceeding 1 500.

Not more than 20 mg/kg of copper in the
complete feedingstuff may come from
cupric chelate of amino acids hydrate

Pigs for fattening:

— in Member States where the mean
density of
the porcine population is
equal to or higher than 175 pigs per
100 ha of utilisable agricultural land:

— up to 16 weeks: 175 (total),

— from 17th week up to slaughter:

35 (total).

— in Member States where the mean
density of
the porcine population is
lower than 175 pigs per 100 ha of
utilisable agricultural land:

— up to 16 weeks: 175 (total),

— from 17th week up to six months:

100 (total),

— over six months up to slaughter:

35 (total).

Breeding pigs: 35 (total).

Other species or categories of animals, with
the exception of calves prior to the start of
rumination and sheep: 35 (total).

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
4
1

EC No

Element

Additive

Chemical formula

Maximum content of the element in mg/kg of
complete feedingstuff

Other provisions

End of period of
authorisation

E 5

Manganese — Mn

Manganous carbon-
ate

MnCO3

250 (total)

Manganous chloride,
tetrahydrate

MnCl2 . 4H2O

250 (total)

Manganous
hydrogen phosphate,
trihydrate

MnHPO4 . 3H2O

250 (total)

Manganous oxide

MnO

250 (total)

Manganic oxide

Mn2O3

250 (total)

Manganous sulphate,
tetrahydrate

MnSO4 . 4H2O

250 (total)

Manganous sulphate,
monohydrate

MnSO4 . H2O

250 (total)

Manganese chelate
of amino acids
hydrate

Mn (x)1-3 . nH2O

250 (total)

(x=anion of any amino
acid derived from
hydrolysed soya protein)

Molecular weight not
exceeding 1 500.

—

—

—

—

—

—

—

Without a time limit

Without a time limit

Without a time limit

Without a time limit

Without a time limit

Without a time limit

Without a time limit

Not more than 40 mg/kg of manganese in
the complete feedingstuff may come from
manganese chelate of amino acids hydrate

Without a time limit

C

5
0
/
4
2

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

Manganomanganic
oxide

MnO Mn2O3

150 (total)

—

Without a time limit

.

.

2
5
2
2
0
0
4

EC No

Element

Additive

Chemical formula

Maximum content of the element in mg/kg of
complete feedingstuff

Other provisions

E 6

Zinc — Zn

Zinc lactate,
trihydrate

Zinc acetate,
dihydrate

Zn(C3H5O3)2 . 3H2O

250 (total)

Zn(CH3COO)2 . 2H2O

250 (total)

Zinc carbonate

ZnCO3

Zinc chloride,
monohydrate

ZnCl2 . H2O

250 (total)

250 (total)

—

—

—

—

End of period of
authorisation

Without a time limit

Without a time limit

Without a time limit

Without a time limit

Zinc oxide

ZnO

250 (total)

Maximum content of lead: 600 mg/kg

Without a time limit

Zinc sulphate,
heptahydrate

Zinc sulphate,
monohydrate

ZnSO4 . 7H2O

250 (total)

ZnSO4 . H2O

250 (total)

Zinc chelate of
amino acids hydrate

Zn (x)1-3 . nH2O

250 (total)

(x=anion of any amino
acid derived from
hydrolysed soya protein)

Molecular weight not
exceeding 1 500.

—

—

Without a time limit

Without a time limit

Not more than 80 mg/kg of zinc in the
complete feedingstuff may come from zinc
chelate of amino acids hydrate

Without a time limit

E 7

Molybdenum — Mo

Ammonium
molybdate

(NH4)6Mo7O24 . 4H2O

2,5 (total)

Sodium molybdate

Na2MoO4 . 2H2O

2,5 (total)

E 8

Selenium — Se

Sodium selenite

Na2SeO3

Sodium selenate

Na2SeO4

0,5 (total)

0,5 (total)

—

—

—

—

Without a time limit

Without a time limit

Without a time limit

Without a time limit

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
4
3

EC No

Additive

Chemical formula, description

Species or
category of animal

Maximum age

Minimum content Maximum content

mg/kg of complete feedingstuff

Other provisions

End of period of
authorisation

C

5
0
/
4
4

Binders, anti-caking agents and coagulants

E 330

Citric acid

C6H8O7

E 470

Sodium, potassium and calcium
stearates

C18H35O2Na

C18H35O2K

C36H70O4Ca

E 516

Calcium sulphate, dihydrate

CaSO4. 2H2O

E 551a

Silicic acid, precipitated and
dried

E 551b

Colloidal silica

E 551c

Kieselgur (diatomaceous earth,
purified)

—

—

—

E 552

Calcium silicate, synthetic

—

E 554

Sodium aluminosilicate,
synthetic

—

All species or
categories of
animals

All species or
categories of
animals

All species or
categories of
animals

All species or
categories of
animals

All species or
categories of
animals

All species or
categories of
animals

All species or
categories of
animals

All species or
categories of
animals

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

All feedingstuffs. Compliance
with the provisions of Article
16(1)(g)

Without a time
limit

E
N

—

All feedingstuffs

Without a time
limit

30 000

All feedingstuffs

—

All feedingstuffs

—

All feedingstuffs

—

All feedingstuffs

—

All feedingstuffs

—

All feedingstuffs

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

EC No

Additive

Chemical formula, description

Species or
category of animal

Maximum age

Minimum content Maximum content

mg/kg of complete feedingstuff

Other provisions

End of period of
authorisation

E 558

Bentonite-montmorillonite

—

All species or
categories of
animals

—

—

20 000

All feedingstuffs.

Without a time
limit

Mixing with additives from the
‘antibiotics', ‘growth promoters',
‘coccidiostats and other medical
substances' groups is prohibited,
except in the case of:

monensin-sodium, narasin,
lasalocid-sodium, flavophosp-
holipol, salinomycin sodium and
robenidine.

Indication on the label of the
specific name of the additive.

E 559

Kaolinitic clays, free of asbestos

Naturally occurring mixtures of
minerals containing at least
65 % complex hydrated
aluminium silicates whose main
constituent is kaolinite

All species or
categories of
animals

—

—

—

All feedingstuffs

E 560

Natural mixtures of steatites and
chlorite

Natural mixtures of steatite and
chlorite, free of asbestos:
minimum purity of the mixtures
85 %

All species or
categories of
animals

—

—

—

All feedingstuffs

—

—

—

All feedingstuffs

Without a time
limit

Without a time
limit

Without a time
limit

E 561

Vermiculite

E 562

Sepiolite

Natural silicate of magnesium,
aluminium and iron, expanded
by heating, free of asbestos

All species or
categories of
animals

Maximum fluorine content:
0,3 %

Hydrated magnesium silicate of
sedimentary origin, containing
at least 60 % sepiolite and
maximum 30 %
montmorillonite, free of asbestos

All species or
categories of
animals

—

—

20 000

All feedingstuffs

Without a time
limit

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
4
5

EC No

Additive

Chemical formula, description

Species or
category of animal

Maximum age

Minimum content Maximum content

mg/kg of complete feedingstuff

Other provisions

E 563

Sepiolitic clay

Hydrated magnesium silicate of
sedimentary origin, containing
at least 40 % sepiolite and 25 %
illite, free of asbestos

All species or
categories of
animals

—

—

20 000

All feedingstuffs

E 565

Lignosulphonates

—

E 566

Natrolite-phonolite

Natural mixture of aluminium
silicates, alkalines and
alkaline-earth and aluminium
hydrosilicates, natrolite (43 to
46,5 %) and feldspar

All species or
categories of
animals

All species or
categories of
animals

E 598

Synthetic calcium aluminates

Mixture of calcium aluminates
containing between 35 and
51 % of AI2O3
Maximum molybdenum content:
20 mg/kg

Poultry

Rabbits

Pigs

Dairy cows

Cattle for
fattening

Calves

Lambs

Kids

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

All feedingstuffs

25 000

All feedingstuffs

20 000

All feedingstuffs

20 000

All feedingstuffs

20 000

All feedingstuffs

8 000

All feedingstuffs

8 000

All feedingstuffs

8 000

All feedingstuffs

8 000

All feedingstuffs

8 000

All feedingstuffs

End of period of
authorisation

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

C

5
0
/
4
6

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

EC No

Additive

Chemical formula, description

Species or
category of animal

Maximum age

Minimum content Maximum content

mg/kg of complete feedingstuff

Other provisions

E 599

Perlite

Natural silicate of sodium and
aluminium, expanded by
heating, free of asbestos

All species or
categories of
animals

—

—

—

All feedingstuffs

Acidity regulators

E 170

Calcium carbonate

296

DL- and L-Malic acid

—

—

Ammonium dihydrogen
orthophosphate

Diammonium hydrogen
orthophosphate

E 339 (i)

Sodium dihydrogen
orthophosphate

E 339 (ii)

Disodium hydrogen
orthophosphate

—

—

—

—

—

—

Dogs

Cats

Dogs

Cats

Dogs

Cats

Dogs

Cats

Dogs

Cats

Dogs

Cats

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

End of period of
authorisation

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
4
7

EC No

Additive

Chemical formula, description

Species or
category of animal

Maximum age

Minimum content Maximum content

mg/kg of complete feedingstuff

Other provisions

E 339 (iii)

Trisodium orthophosphate

E 340 (i)

Potassium dihydrogen
orthophosphate

E 340 (ii)

Dipotassium hydrogen
orthophosphate

E 340 (iii)

Tripotassium orthophosphate

E 341 (i)

Calcium tetrahydrogen
diorthophosphate

E 341 (ii)

Calcium hydrogen
orthophosphate

E 350 (i)

Sodium malate (Salt of DL- or
L-Malic Acid)

—

—

—

—

—

—

—

Dogs

Cats

Dogs

Cats

Dogs

Cats

Dogs

Cats

Dogs

Cats

Dogs

Cats

Dogs

Cats

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

C

5
0
/
4
8

End of period of
authorisation

Without a time
limit

Without a time
limit

E
N

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

EC No

Additive

Chemical formula, description

Species or
category of animal

Maximum age

Minimum content Maximum content

mg/kg of complete feedingstuff

Other provisions

E 450a (i)

Disodium dihydrogen
diphosphate

E 450a (iii)

Tetrasodium diphosphate

E 450a (iv)

Tetrapotassium diphosphate

E 450b (i)

Pentasodium triphosphate

E 450b (ii)

Pentapotassium triphosphate

E 500 (i)

Sodium carbonate

E 500 (ii)

Sodium hydrogen carbonate

—

—

—

—

—

—

—

Dogs

Cats

Dogs

Cats

Dogs

Cats

Dogs

Cats

Dogs

Cats

Dogs

Cats

Dogs

Cats

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

.

.

2
5
2
2
0
0
4

End of period of
authorisation

Without a time
limit

Without a time
limit

E
N

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
4
9

EC No

Additive

Chemical formula, description

Species or
category of animal

Maximum age

Minimum content Maximum content

mg/kg of complete feedingstuff

Other provisions

E 500 (iii)

Sodium sesquicarbonate

E 501 (ii)

Potassium hydrogen carbonate

E 503 (i)

Ammonium carbonate

E 503 (ii)

Ammonium hydrogen carbonate

E 507

Hydrochloric acid

E 510

Ammonium chloride

E 513

Sulphuric acid

—

—

—

—

—

—

—

Dogs

Cats

Dogs

Cats

Dogs

Cats

Dogs

Cats

Dogs

Cats

Dogs

Cats

Dogs

Cats

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

C

5
0
/
5
0

End of period of
authorisation

Without a time
limit

Without a time
limit

E
N

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

EC No

Additive

Chemical formula, description

Species or
category of animal

Maximum age

Minimum content Maximum content

mg/kg of complete feedingstuff

Other provisions

E 524

Sodium hydroxide

E 525

Potassium hydroxide

E 526

Calcium hydroxide

E 529

Calcium oxide

E 540

Dicalcium diphosphate

—

—

—

—

—

Dogs

Cats

Dogs

Cats

Dogs

Cats

Dogs

Cats

Dogs

Cats

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

—

.

.

2
5
2
2
0
0
4

End of period of
authorisation

Without a time
limit

Without a time
limit

E
N

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

Without a time
limit

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
5
1

EC No

Additive

Chemical formula, description Species or category of animal Maximum age

Minimum
content

Maximum
content

Units of activity/kg of
complete feedingstuff

Other provisions

End of period
of
authorisation

Enzymes

E 1600

3-Phytase

EC 3.1.3.8

Piglets

Preparation of 3-phytase
produced by Aspergillus
niger (CBS 114.94)
having a minimum
activity of:

Solid form:
5 000 FTU (3)/g

Liquid form:
5 000 FTU/ml

Two
months

500 FTU

—

1.

In the directions for use of the additive and
premixture, indicate the storage temperature,
storage life, and stability to pelleting.

Without a
time limit

2. Recommended dose per kilogram of complete

feedingstuff: 500 FTU.

3.

For use in compound feed containing more than
0,23 % phytin bound phosphorus.

Pigs for fattening

—

280 FTU

—

1.

In the directions for use of the additive and
premixture, indicate the storage temperature,
storage life, and stability to pelleting.

Without a
time limit

2. Recommended dose per kilogram of complete

feedingstuff: 400-500 FTU.

3.

For use in compound feed containing more than
0,23 % phytin bound phosphorus.

Sows

—

500 FTU

—

1.

In the directions for use of the additive and
premixture, indicate the storage temperature,
storage life, and stability to pelleting.

Without a
time limit

2. Recommended dose per kilogram of complete

feedingstuff: 500 FTU.

3.

For use in compound feed containing more than
0,36 % phytin bound phosphorus.

C

5
0
/
5
2

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

EC No

Additive

Chemical formula, description Species or category of animal Maximum age

Minimum
content

Maximum
content

Units of activity/kg of
complete feedingstuff

Other provisions

End of period
of
authorisation

.

.

2
5
2
2
0
0
4

Chickens for fattening

—

375 FTU

—

1.

In the directions for use of the additive and
premixture, indicate the storage temperature,
storage life, and stability to pelleting.

Without a
time limit

E
N

Laying hens

—

250 FTU

—

E 1601

Endo-1,3(4)-beta-
glucanase

EC 3.2.1.6

Endo-1,4-beta-xylanase

EC 3.2.1.8

Preparation of
endo-1,3(4)-beta-glucan-
ase and
endo-1,4-beta-xylanase
produced by Aspergillus
niger (NRRL 25541)
having a minimum
activity of:

Endo-1,3(4)-beta-
glucanase:
1 100 IU (4)/g

Endo-1,4-beta-
xylanase:
1 600 IU (5)/g

Chickens for fattening

—

—

—

endo-1,3
(4)-beta-
glucanase:
138 U

endo-
1,4-beta-
xylanase:
200 U

2. Recommended dose per kilogram of complete

feedingstuff: 500-700 FTU.

3.

1.

For use in compound feed containing more than
0,23 % phytin bound phosphorus.

In the directions for use of the additive and
premixture, indicate the storage temperature,
storage life, and stability to pelleting.

Without a
time limit

2. Recommended dose per kilogram of complete

feedingstuff: 300-400 FTU.

3.

1.

For use in compound feed containing more than
0,23 % phytin bound phosphorus.

In the directions for use of the additive and
premixture, indicate the storage temperature,
storage life, and stability to pelleting.

Without a
time limit

2. Recommended dose per kilogram of complete

feedingstuff:

endo-1,3(4)-beta-glucanase: 138 U

endo-1,4-beta-xylanase: 200 U.

3.

For use in compound feed rich in non-starch
polysaccharides (mainly arabinoxylans and
beta-glucans), for example mixed diet containing
cereals (e.g. barley, wheat, rye, triticale).

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
5
3

EC No

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

CFU/kg of complete feedingstuff

Other provisions

End of period of
authorisation

Micro-organisms

E 1700

Bacillus licheniformis
(DSM 5749)

Bacillus subtilis
(DSM 5750)

(In a 1/1 ratio)

E 1701

Bacillus cereus var. toyoi
NCIMB 40112/
CNCM I – 1012

Mixture of Bacillus
licheniformis and Bacillus
subtilis containing a
minimum of

3,2 x 109 CFU/g of the
additive (1,6 x 109 CFU/g of
each bacterium)

Preparation of Bacillus cereus
var. toyoi containing a
minimum of 1 × 1010 CFU/g
additive

E 1702

Saccharomyces cerevisiae
NCYC Sc 47

Preparation of Saccharomyces
cerevisiae containing a
minimum of 5 × 109 CFU/g
additive

Piglets

Two months

1,28 x 109

3,2 x 109

Piglets

2 months

1 × 109

1 × 109

Sows

0,5 × 109

2 × 109

from 1 week
prior to
farrowing
until weaning

Cattle for fattening

—

4 × 109

8 × 109

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

Without a
time limit

Without a
time limit

Without a
time limit

Without a
time limit

In the directions for use of
the additive and premixture
indicate the storage
temperature, storage life and
stability to pelleting.

In the directions for use of
the additive and premixture
indicate the storage
temperature, storage life and
stability to pelleting.

In the directions for use of
the additive and the
premixture, indicate the
storage temperature, storage
life and stability to pelletting.

Indicate in the instructions
for use: ‘the quantity of
Saccharomyces cerevisae in the
daily ration must not exceed
2,5 × 109 CFU for 100 kg of
bodyweight and 0,5 × 1010
CFU for each additional
100 kg of bodyweight'.

C

5
0
/
5
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No (or EC No)

Additive

Chemical formula, description

Species or
category of animal

Maximum age

Minimum content Maximum content

mg/kg of complete feedingstuff

Other provisions

End of period of
authorisation

Radionuclide binders

1. Radioactive caesium binders (137Cs and 134 Cs)

1.1.

Ferric (III) ammonium
hexacyanoferrate (II)

NH4Fe(III)[Fe(II)(CN)6)]

Ruminants
(domestic and
wild)

—

50

500

Indicate in the instructions for
use:

Without a time limit

‘Only for limited geographical
areas in case of contamination
with radionuclides'.

‘The quantity of ferric (III)
ammonium hexacyanoferrate (II)
in the daily ration must be
between 10 mg and 150 mg for
10 kg of body weight'.

Calves prior to
the start of
rumination

—

50

500

Indicate in the instructions for
use:

Without a time limit

‘Only for limited geographical
areas in case of contamination
with radionuclides'.

‘The quantity of ferric (III)
ammonium hexacyanoferrate (II)
in the daily ration must be
between 10 mg and 150 mg for
10 kg of body weight'.

Lambs prior to
the start of
rumination

—

50

500

Indicate in the instructions for
use:

Without a time limit

‘Only for limited geographical
areas in case of contamination
with radionuclides'.

‘The quantity of ferric (III)
ammonium hexacyanoferrate (II)
in the daily ration must be
between 10 mg and 150 mg for
10 kg of body weight'.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
5
5

No (or EC No)

Additive

Chemical formula, description

Species or
category of animal

Maximum age

Minimum content Maximum content

mg/kg of complete feedingstuff

Other provisions

End of period of
authorisation

Kids prior to
the start of
rumination

—

50

500

Indicate in the instructions for
use:

Without a time limit

‘Only for limited geographical
areas in case of contamination
with radionuclides'.

‘The quantity of ferric (III)
ammonium hexacyanoferrate (II)
in the daily ration must be
between 10 mg and 150 mg for
10 kg of body weight'.

Pigs (domestic
and wild)

—

50

500

Indicate in the instructions for
use:

Without a time limit

‘Only for limited geographical
areas in case of contamination
with radionuclides'.

‘The quantity of ferric (III)
ammonium hexacyanoferrate (II)
in the daily ration must be
between 10 mg and 150 mg for
10 kg of body weight'.

C

5
0
/
5
6

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

CHAPTER IV: LIST OF OTHER ADDITIVES AUTHORISED ON A PROVISIONAL BASIS FOR NO LONGER THAN FOUR YEARS OR FIVE YEARS IN THE CASE OF ADDITIVES WHICH HAVE

BEEN THE SUBJECT OF PROVISIONAL AUTHORISATION BEFORE 1 APRIL 1998

No (or EC No)

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

mg/kg of complete feedingstuff

Other provisions

End of period of
authorisation

Colourants, including pigments

1. Carotenoids and xanthophylls

E 160a

Beta-carotene

E 161g

Canthaxanthin

C40H56

C40H52O2

12

Astaxanthin-rich Phaffia
rhodozyma (ATCC 74219)

Concentrated biomass of the
yeast Phaffia rhodozyma
(ATCC 74219), killed,
containing at least 4,0 g
astaxanthin per kilogram of
additive and having a
maximum ethoxyquin
content of 2 000 mg/kg.

Canaries

Pet and ornamental birds

Salmon

—

—

—

—

—

—

—

—

100

14.12.2003 (c)

14.12.2003 (c)

14.12.2003 (c)

—

—

The maximum content is
expressed as astaxanthin.

Use permitted only from the
age of six months onwards.

The mixture of the additive
with canthaxanthin is allowed
provided that the total
concentration of astaxanthin
and canthaxanthin does not
exceed 100 mg/kg in the
complete feedingstuff.

Ethoxyquin content to be
declared.

Trout

—

—

100

The maximum content is
expressed as astaxanthin.

14.12.2003 (c)

Use permitted only from the
age of six months onwards.

The mixture of the additive
with canthaxanthin is allowed
provided that the total
concentration of astaxanthin
and canthaxanthin does not
exceed 100 mg/kg in the
complete feedingstuff.

Ethoxyquin content to be
declared.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
5
7

No (or EC No)

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

mg/kg of complete feedingstuff

Other provisions

End of period of
authorisation

C

5
0
/
5
8

2. Other colourants

E 102

Tartrazine

C16H9N4O9S2Na3

Grain-eating ornamental birds

Small rodents

E 110

Sunset yellow FCF

C16H10N2O7S2Na2

Grain-eating ornamental birds

E 131

Patent blue V

Small rodents

Calcium salt of the
disulphonic acid of
m-hydroxytetraethyldiamino
triphenylcarbinol anhydride

Grain-eating ornamental birds

Small rodents

E 141

Chlorophyll copper complex —

Grain-eating ornamental birds

Small rodents

Preservatives

1

Sodium benzoate: 140 g/kg

Additive composition:

Pigs

Propionic acid: 370 g/kg

Sodium benzoate: 140 g/kg

Sodium propionate: 110 g/kg

Propionic acid: 370 g/kg

Sodium propionate: 110 g/kg

Dairy cows

—

—

—

—

—

—

—

—

—

—

Water: 380 g/kg

Active substance:

Sodium benzoate, C7H5O2Na

Propionic acid, C3H6O2

Sodium propionate,
C3H5O2Na

—

—

—

—

—

—

—

—

150

150

150

150

150

150

150

150

—

—

—

—

—

—

—

—

30.9.2004 (p)

E
N

30.9.2004 (p)

30.9.2004 (p)

30.9.2004 (p)

30.9.2004 (p)

30.9.2004 (p)

30.9.2004 (p)

30.9.2004 (p)

3 000

22 000

3 000

22 000

For the preservation of grain
having a moisture content in
excess of 15 %.

1.8.2006 (w)

For the preservation of grain
having a moisture content in
excess of 15 %.

1.8.2006 (w)

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No (or EC No)

Element

Additive

Chemical formula

Maximum content of the element in mg/kg of complete feedingstuff

Other provisions

Trace elements

E4

Copper — Cu

Copper-lysine
sulphate

Cu(C6H13N2O2)2 . SO4

Pigs for fattening:

— in Member States where the mean density of

the porcine
population is equal to or higher than 175 pigs per 100 ha of
utilisable agricultural land:

— up to 16 weeks: 175 (total)

— in Member States where the mean density of

the porcine
population is lower than 175 pigs per 100 ha of utilisable
agricultural land:

— up to 16 weeks: 175 (total).

Pigs for fattening:

— in Member States where the mean density of

the porcine
population is equal to or higher than 175 pigs per 100 ha of
utilisable agricultural land:

— from 17th week up to slaughter: 35 (total),

— in Member States where the mean density of

the porcine
population is lower than 175 pigs per 100 ha of utilisable
agricultural land:

— from 17th week up to six months: 100 (total),

— over six months up to slaughter: 35 (total).

Breeding pigs: 35 (total).

Other species or categories of animals, with the exception of calves
prior to the start of rumination and sheep: 35 (total).

End of period of
authorisation

31.3.2004 (d)

Not more than 50 mg/kg
of copper in the complete
feedingstuff may come
from copper-lysine
sulphate.

31.3.2004 (d)

Not more than 25 mg/kg
of copper in the complete
feedingstuffs may come
from copper-lysine
sulphate.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
5
9

No (or EC No)

Additive

Chemical formula, description

Species or category of animal

Maximum age

Binders, anti-caking agents and coagulants

3

4

Clinoptilolite of volcanic
origin

Pigs

Rabbits

Poultry

Calcium hydrated
aluminosilicate of volcanic
origin containing a
minimum of 85 % of
clinoptilolite and a
maximum of 15 % of
feldspar, micas and clays free
of fibres and quartz

Maximum lead content: 80
mg/kg

Clinoptilolite of sedimentary
origin

Hydrated calcium
aluminosilicate of
sedimentary origin
containing at least 80 %
clinoptilolite and a
maximum 20 % of clay
minerals, free of fibres and
quartz

Pigs for fattening

Chickens for fattening

Turkeys for fattening

Bovines

Salmon

E 535

Sodium Ferrocyanide

Na4[Fe(CN)6]. 10H2O

All species or categories of
animals

E 536

Potassium Ferrocyanide

K4[Fe(CN)6]. 3H2O

All species or categories of
animals

Acidity regulators

—

—

—

—

—

—

—

—

—

—

Minimum
content

Maximum
content

mg/kg of complete feedingstuff

Other provisions

End of period of
authorisation

C

5
0
/
6
0

—

—

—

—

—

—

—

—

—

—

20 000

All feedingstuffs

21.4.2004 (e)

E
N

20 000

All feedingstuffs

21.4.2004 (e)

20 000

All feedingstuffs

21.4.2004 (e)

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

20 000

All feedingstuffs

26.9.2004 (n)

20 000

All feedingstuffs

26.9.2004 (n)

20 000

All feedingstuffs

26.9.2004 (n)

20 000

All feedingstuffs

26.9.2004 (n)

20 000

All feedingstuffs

26.9.2004 (n)

—

—

Maximum content:
80 mg/kg NaCl (calculated as
ferrocyanide anion)

1.3.2006 (u)

Maximum content:
80 mg/kg NaCl (calculated as
ferrocyanide anion)

1.3.2006 (u)

E 210

Benzoic acid

C7H6O2

Pigs for fattening

—

5 000

10 000

—

25.5.2007 (ad)

.

.

2
5
2
2
0
0
4

No
(or EC No)

Enzymes

1

2

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

End of period of
authorisation

3-Phytase
EC 3.1.3.8

Preparation of 3-phytase produced
by Aspergillus niger (CBS 114.94)
having a minimum phytase
activity of 5 000 FTU (3)/g for
solid and liquid preparations

3-Phytase
EC 3.1.3.8

Preparation of 3-phytase produced
by Aspergillus oryzae (DSM 10 289)
having a minimum activity of:
Coated form: 2 500 FYT (7)/g

Liquid form: 5 000 FYT/g

Turkeys

—

125 FTU

—

1.

Indicate in the directions for use for
the additive and the premixture the
storage temperature, storage duration
and stability on pelleting.

14.12.2003 (c)

2. Recommended dose per kg of

complete feedingstuff: 200-800 FTU.

3.

For use in compound feedingstuffs
with a minimum content of 0,3 %
phytate, e.g. 20 % wheat.

Piglets

Four
months

250 FYT

1 000 FYT

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

30.6.2004 (f)

2. Recommended dose per kg of

complete feedingstuff: 500 FYT.

3.

For use in compound feed rich in
phytates, e.g. containing more than
40 % cereals (maize, barley, oats,
wheat, rye, triticale), oilseeds and
pulses.

Pigs for
fattening

—

400 FYT

1 000 FYT

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

30.6.2004 (f)

2. Recommended dose per kg of

complete feedingstuff: 500 FYT

3.

For use in compound feed rich in
phytates, e.g. containing more than
40 % cereals (maize, barley, oats,
wheat, rye, triticale), oilseeds and
pulses.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
6
1

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

End of period of
authorisation

Chickens for
fattening

—

200 FYT

1 000 FYT

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

30.6.2004 (f)

2. Recommended dose per kg of

complete feedingstuff: 500 FYT.

3.

For use in compound feed rich in
phytates, e.g. containing more than
40 % cereals (maize, barley, oats,
wheat, rye, triticale), oilseeds and
pulses.

Laying hens

—

500 FYT

1 000 FYT

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

30.6.2004 (g)

2. Recommended dose per kg of

complete feedingstuff: 750 FYT.

3.

For use in compound feed rich in
phytates, e.g. containing more than
40 % cereals (maize, barley, oats,
wheat, rye, triticale), oilseeds and
pulses.

C

5
0
/
6
2

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

3

Alpha-galactosidase
EC 3.2.1.22

Preparation of alpha-galactosidase
produced by Aspergillus oryzae
(DSM 10 286) having a minimum
activity of:
Liquid form: 1 000 GALU (8)/g

Chickens for
fattening

—

300 GALU

1 000 GALU

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

30.6.2004 (f)

2. Recommended dose per kg of

complete feedingstuff: 450 GALU.

3.

For use in compound feed rich in
oligosaccharides, e.g. containing more
than 25 % soy meal, cotton seed
cakes, peas.

.

.

2
5
2
2
0
0
4

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

End of period of
authorisation

4

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Preparation of
endo-1,3(4)-beta-glucanase pro-
duced by Aspergillus aculeatus (CBS
589.94) having a minimum
activity of:
Coated form: 50 FBG (9)/g

Liquid form: 120 FBG/ml

Piglets

Four
months

25 FBG

40 FBG

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

30.6.2004 (f)

2. Recommended dose per kg of
complete feedingstuff: 25 FBG.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans), e.g. containing more
than 50 % maize or barley.

Chickens for
fattening

—

10 FBG

100 FBG

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

1.4.2004 (l)

2. Recommended dose per kg of
complete feedingstuff: 20 FBG.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans), e.g. containing more
than 60 % maize.

5

Endo-1,4-beta-xyla-
nase
EC 3.2.1.8

Preparation of
endo-1,4-beta-xylanase produced
by Aspergillus oryzae (DSM 10287)
having a minimum activity of:
Coated form: 1 000 FXU (10)/g

Liquid form: 650 FXU/ml

Chickens for
fattening

—

80 FXU

200 FXU

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

30.6.2004 (f)

2. Recommended dose per kg of

complete feedingstuff: 150 FXU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans), e.g. containing more
than 50 % wheat.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
6
3

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

End of period of
authorisation

Turkeys for
fattening

—

225 FXU

600 FXU

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

30.6.2004 (f)

2. Recommended dose per kg of

complete feedingstuff: 225-600 FXU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans), e.g. containing more
than 50 % wheat.

Piglets

Four
months

200 FXU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

30.6.2004 (f)

6

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Endo-1,4-beta-
glucanase
EC 3.2.1.4

Preparation of
endo-1,4-beta-xylanase and
endo-1,4-beta-glucanase produced
by Humicola insolens (DSM 10442)
having a minimum activity of:

Chickens for
fattening

—

200 FXU

19 FBG

Coated form:
800 FXU (11)/g
75 FBG (9)/g

Microgranulated form:

800 FXU/g

75 FBG/g

Liquid form:

550 FXU/ml

50 FBG/ml

2. Recommended dose per kg of

complete feedingstuff: 200 FXU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans), e.g.containing more
than 50 % wheat.

1 000 FXU

1.

94 FBG

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

30.6.2004 (f)

2. Recommended dose per kg of

complete feedingstuff:

400 FXU

38 FBG.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta- glucans), e.g.
containing more than 30 % barley
and/or oats, wheat.

C

5
0
/
6
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Piglets

Four
months

240 FXU

22 FBG

1 000 FXU

1.

94 FBG

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

400 FXU

38 FBG.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta-glucans), e.g.
containing more than 30 % barley
and/or oats, wheat.

End of period of
authorisation

30.6.2004 (f)

Pigs for
fattening

—

200 FXU

19 FBG

800 FXU

1.

75 FBG

In the conditions of use of the
additive and premixture, indicate the
storage temperature, storage life, and
the stability to pelleting.

30.6.2004 (h)

2. Recommended dose per kg of

complete feedingstuff:

400 FXU

38 FBG.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta-glucans), e.g.
containing more than 30 % barley,
and/or oats, wheat.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
6
5

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

End of period of
authorisation

1.4.2004 (l)

No
(or EC No)

7

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Endo-1,4-beta-
glucanase
EC 3.2.1.4

Preparation of
endo-1,4-beta-xylanase and
endo-1,4-beta-glucanase produced
by Aspergillus niger (CBS 600.94)
having a minimum activity of:

Coated form:
36 000 FXU (12)/g
15 000 BGU (13)/g

Liquid form:

36 000 FXU/g

15 000 BGU/g

Chickens for
fattening

—

3 600 FXU

1 500 BGU

12 000 FXU

1.

5 000 BGU

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

Piglets

Four
months

6 000 FXU

2 500 BGU

—

—

2. Recommended dose per kg of

complete feedingstuff:

3 600-6 000 FXU

1 500-2 500 BGU.

3.

1.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta-glucans), e.g.
containing more than 35 % barley
and 20 % wheat.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

1.4.2004 (l)

2. Recommended dose per kg of

complete feedingstuff:

6 000 FXU

2 500 BGU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta-glucans), e.g.
containing more than 30 % wheat
and 30 % barley.

C

5
0
/
6
6

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Turkeys for
fattening

—

6 000 FXU

2 500 BGU

12 000 FXU

1.

5 000 BGU

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

End of period of
authorisation

1.4.2004 (l)

Laying hens

—

12 000 FXU

5 000 BGU

—

—

2. Recommended dose per kg of

complete feedingstuff:

6 000-12 000 FXU

2 500-5 000 BGU.

3.

1.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta-glucans), e.g.
containing more than 40 % wheat.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

1.4.2004 (l)

2. Recommended dose per kg of

complete feedingstuff:

12 000 FXU

5 000 BGU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta-glucans), e.g.
containing more than 20 % wheat,
10 % barley and 20 % sunflower.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
6
7

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

End of period of
authorisation

30.9.2004 (p)

Preparation of
endo-1,4-beta-xylanase and
endo-1,4-beta-glucanase produced
by Aspergillus niger (CBS 600.94)
having a minimum activity of:

Solid form:
36 000 FXU (12)/g
15 000 BGU (13)/g

Chickens for
fattening

—

3 600 FXU

1 500 BGU

12 000 FXU

1.

5 000 BGU

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

Piglets

Four
months

6 000 FXU

2 500 BGU

—

—

2. Recommended dose per kg of

complete feedingstuff:

3 600-6 000 FXU

1 500-2 500 BGU.

3.

1.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta-glucans), e.g.
containing more than 35 % barley
and 20 % wheat.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

30.9.2004 (p)

2. Recommended dose per kg of

complete feedingstuff:

6 000 FXU

2 500 BGU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta-glucans), e.g.
containing more than 30 % wheat
and 30 % barley.

C

5
0
/
6
8

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Turkeys for
fattening

—

6 000 FXU

2 500 BGU

12 000 FXU

1.

5 000 BGU

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

End of period of
authorisation

30.9.2004 (p)

Laying hens

—

12 000 FXU

5 000 BGU

—

—

2. Recommended dose per kg of

complete feedingstuff:

6 000-12 000 FXU

2 500-5 000 BGU.

3.

1.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta-glucans), e.g.
containing more than 40 % wheat.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

30.9.2004 (p)

2. Recommended dose per kg of

complete feedingstuff:

12 000 FXU

5 000 BGU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta-glucans), e.g.
containing more than 20 % wheat,
10 % barley and 20 % sunflower.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
6
9

No
(or EC No)

8

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Endo-1,4-beta-
glucanase
EC 3.2.1.4

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Preparation of
endo-1,4-beta-glucanase and
endo-1,4-beta-xylanase produced
by Aspergillus niger (CBS 600.94)
having a minimum activity of:

Coated form:
10 000 BGU (13)/g
4 000 FXU (12)/g

Liquid form:

20 000 BGU/g

8 000 FXU/g

Chickens for
fattening

—

3 000 BGU

1 200 FXU

10 000 BGU

1.

4 000 FXU

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

3 000-10 000 BGU

1 200-4 000 FXU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans and arabinoxylans), e.g.
containing more than 60 % barley.

End of period of
authorisation

1.4.2004 (l)

Piglets

Four
months

3 000 BGU

1 200 FXU

5 000 BGU

1.

2 000 FXU

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

1.4.2004 (l)

2. Recommended dose per kg of

complete feedingstuff:

3 000-5 000 BGU

1 200-2 000 FXU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans and arabinoxylans), e.g.
containing more than 30 % barley.

C

5
0
/
7
0

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Laying hens

—

5 000 BGU

2 000 FXU

—

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

5 000 BGU

2 000 FXU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans and arabinoxylans), e.g.
containing more than 60 % barley.

End of period of
authorisation

1.4.2004 (l)

Preparation of
endo-1,4-beta-glucanase and
endo-1,4-beta-xylanase produced
by Aspergillus niger (CBS 600.94)
having a minimum activity of:

Solid form:
20 000 BGU (13)/g
8 000 FXU (12)/g

Chickens for
fattening

—

3 000 BGU

1 200 FXU

10 000 BGU

1.

4 000 FXU

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

30.9.2004 (p)

2. Recommended dose per kg of

complete feedingstuff:

3 000-10 000 BGU

1 200-4 000 FXU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans and arabinoxylans), e.g.
containing more than 60 % barley.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
7
1

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Piglets

Four
months

3 000 BGU

1 200 FXU

5 000 BGU

1.

2 000 FXU

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

End of period of
authorisation

30.9.2004 (p)

Laying hens

—

5 000 BGU

2 000 FXU

—

—

2. Recommended dose per kg of

complete feedingstuff:

3 000-5 000 BGU

1 200-2 000 FXU.

3.

1.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans and arabinoxylans), e.g.
containing more than 30 % barley.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

30.9.2004 (p)

2. Recommended dose per kg of

complete feedingstuff:

5 000 BGU

2 000 FXU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans and arabinoxylans), e.g.
containing more than 60 % barley.

C

5
0
/
7
2

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No
(or EC No)

9

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Preparation of
endo-1,4-beta-xylanase produced
by Aspergillus niger (CBS 270.95)
having a minimum activity of:
Solid form: 28 000 EXU (14)/g

Liquid form: 14 000 EXU/ml

Chickens for
fattening

—

1 400 EXU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

1 400 EXU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans), e.g. containing more
than 50 % wheat.

End of period of
authorisation

30.6.2004 (f)

Laying hens

—

2 400 EXU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

1.4.2004 (l)

2. Recommended dose per kg of

complete feedingstuff:

2 400-7 400 EXU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans) e.g. containing more
than 30 % wheat and 30 % rye.

Turkeys for
fattening

—

2 400 EXU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

1.4.2004 (l)

2. Recommended dose per kg of

complete feedingstuff:

2 400-5 600 EXU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans) e.g. containing more
than 30 % wheat and 30 % rye.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
7
3

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

10

Alpha-amylase
EC 3.2.1.1

Preparation of alpha-amylase
produced by Bacillus
amyloliquefaciens (CBS 360.94)
having a minimum activity of:
Solid form: 45 000 RAU (15)/g

Liquid form: 20 000 RAU/ml

Piglets

Four
months

1 800 RAU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

1 800 RAU.

3.

For use, exclusively, in compound
feed destined for liquid feeding
systems, and containing starch-rich
feed materials (e.g. containing more
than 35 % wheat).

End of period of
authorisation

30.6.2004 (f)

Pigs for
fattening

—

1 800 RAU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

30.6.2004 (f)

2. Recommended dose per kg of

complete feedingstuff:

1 800 RAU.

3.

For use, exclusively, in compound
feed destined for liquid feeding
systems, and containing starch-rich
feed materials (e.g. containing more
than 35 % wheat).

C

5
0
/
7
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Sows

—

1 800 RAU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

End of period of
authorisation

30.6.2004 (f)

Chickens for
fattening

—

endo-1,4-beta-
glucanase: 400 U

endo-1,3(4)-beta-gluc-
anase: 900 U

endo-1,4-beta-
xylanase: 1 300 U

—

—

—

11

Endo-1,4-beta-
glucanase
EC 3.2.1.4

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Preparation of
endo-1,4-beta-glucanase, endo-
1,3(4)-beta-glucanase and
endo-1,4-beta-xylanase produced
by Trichoderma longibrachiatum
(ATCC
74 252) having a minimum
activity of:

Liquid form:

Endo-1,4-beta-glucanase:
8 000 U (16)/ml

Endo-1,3(4)-beta-glucanase:
18 000 U (17)/ml

Endo-1,4-beta-xylanase:
26 000 U (18)/ml

2. Recommended dose per kg of

complete feedingstuff:

1 800 RAU.

3.

1.

For use, exclusively, in compound
feed destined for liquid feeding
systems, and containing starch-rich
feed materials (e.g. containing more
than 35 % wheat).

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

30.6.2004 (f)

2. Recommended dose per kg of

complete feedingstuff:

endo-1,4-beta-glucanase:
400-1 600 U

endo-1,3(4)-beta-glucanase:
900-3 600 U

endo-1,4-beta-xylanase:
1 300-5 200 U.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta-glucans), e.g.
containing more than 30 % wheat or
barley and more than 10 % rye.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
7
5

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Chickens for
fattening

—

endo-1,4-beta-
glucanase: 400 U

endo-1,3(4)-beta-gluc-
anase: 900 U

endo-1,4-beta-
xylanase: 1 300 U

Turkeys for
fattening

—

endo-1,4-beta-
glucanase: 400 U

endo-1,3(4)-beta-gluc-
anase: 900 U

endo-1,4-beta-
xylanase: 1 300 U

—

—

—

—

—

—

Preparation of
endo-1,4-beta-glucanase, endo-
1,3(4)-beta-glucanase and
endo-1,4-beta-xylanase produced
by Trichoderma longibrachiatum
(ATCC
74 252) having a minimum
activity of:

Granular form:

Endo-1,4-beta-glucanase:
8 000 U (16)/g

Endo-1,3(4)-beta-glucanase:
18 000 U (17)/g

Endo-1,4-beta-xylanase:
26 000 U (18)/g

Preparation of
endo-1,4-beta-glucanase, endo-
1,3(4)-beta-glucanase and
endo-1,4-beta-xylanase produced
by Trichoderma longibrachiatum
(ATCC
74 252) having a minimum
activity of:

Liquid and granular form:

Endo-1,4-beta-glucanase:
8 000 U (16)/ml or g

Endo-1,3(4)-beta-glucanase:
18 000 U (17)/ml or g

Endo-1,4-beta-xylanase:
26 000 U (18)/ml or g

End of period of
authorisation

31.5.2005 (r)

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,4-beta-glucanase: 400-1 600 U

endo-1,3(4)-beta-glucanase:
900-3 600 U

endo-1,3(4)-beta-glucanase:
900-3 600 U

endo-1,4-beta-xylanase: 1 300-5 200
U.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta-glucans), e.g.
containing more than 30 % wheat or
barley and more than 10 % rye.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

31.5.2005 (r)

3.

1.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,4-beta-glucanase:
400 - 800 U

endo-1,3(4)-beta-glucanase:
900 - 1 800 U

endo-1,4-beta-xylanase:
1 300 - 2 600 U.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta-glucans), e.g.
containing more than 40 % wheat.

C

5
0
/
7
6

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Laying hens

—

endo-1,4-beta-glucan-
ase: 400 U

endo-1,3(4)-beta-gluc-
anase: 900 U

endo-1,
4-beta-xylanase:
1 300 U

Piglets

—

endo-1,4-beta-glucan-
ase: 400 U

endo-1,3(4)-beta-gluc-
anase: 900 U

endo-1,4-beta-xylana-
se: 1 300 U

—

—

—

—

—

—

End of period of
authorisation

1.1.2007 (y)

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

2. Recommended dosages per kg of

complete feedingstuff:

endo-1,4-beta-glucanase: 400-1 280 U

endo-1,3(4)-beta-glucanase:
900-2 880 U

endo-1, 4-beta-xylanase:
1 300-4 160 U.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta-glucans), e.g.
containing more than 40 % wheat,
triticale or barley.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

1.1.2007 (y)

3.

1.

2. Recommended dosages per kg of

complete feedingstuff:

endo-1,4-beta-glucanase: 400-1 600 U

endo-1,3(4)-beta-glucanase:
900-3 600 U

endo-1, 4-beta-xylanase:
1 300-5 200 U

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta-glucans), e.g.
containing more than 40 % wheat,
triticale or maize or wheat and 20 %
rye.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
7
7

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

No
(or EC No)

12

Chickens for
fattening

—

endo-1,4-beta-
glucanase: 200 U

endo-1,3(4)-beta-gluc-
anase: 450 U

endo-1,4-beta-
xylanase: 650 U

Endo-1,4-beta-
glucanase
EC 3.2.1.4

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Preparation of
endo-1,4-beta-glucanase, endo-
1,3(4)-beta-glucanase and
endo-1,4-beta-xylanase produced
by Trichoderma viride (FERM
BP-4447) having a minimum
activity of:

Endo-1,4-beta-glucanase:
8 000 U (16)/g

Endo-1,3(4)-beta-glucanase:
18 000 U (17)/g

Endo-1,4-beta-xylanase:
26 000 U (18)/g

Laying hens

—

endo-1,4-beta-
glucanase: 640 U

endo-1,3(4)-beta-gluc-
anase: 1 440 U

endo-1,4-beta-
xylanase: 2 080 U

—

—

—

—

—

—

End of period of
authorisation

30.6.2004 (f)

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,4-beta-glucanase:
800-1 200 U

endo-1,3(4)-beta-glucanase:
1 800-2 700 U

endo-1,4-beta-xylanase:
2 600-3 900 U.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta-glucans), e.g.
containing more than 20 % wheat
and 20 % barley, and/or 25 % rye.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

30.6.2004 (f)

3.

1.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,4-beta-glucanase:
640-1 280 U

endo-1,3(4)-beta-glucanase:
1 440-2 880 U

endo-1,4-beta-xylanase:
2 080-4 160 U.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta-glucans), e.g.
containing more than 20 % wheat
and 20 % barley and/or 25 % rye.

C

5
0
/
7
8

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

—

—

—

—

—

Turkeys for
fattening

—

endo-1,4-beta-
glucanase: 800 U

endo-1,3(4)-beta-
glucanase: 1 800 U

endo-1,4-beta-
xylanase: 2 600 U

13

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Preparation of
endo-1,3(4)-beta-glucanase and
endo-1,4-beta-xylanase produced
by Trichoderma longibrachiatum
(CBS 357.94) having a minimum
activity of:

Chickens for
fattening

—

100 BGU

130 EXU

Powder form:
8 000 BGU (19)/g
11 000 EXU (20)/g

Granulated form:

6 000 BGU/g

8 250 EXU/g

Liquid form:

2 000 BGU/ml

2 750 EXU/ml

End of period of
authorisation

30.6.2004 (f)

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,4-beta-glucanase:
800-1 200 U

endo-1,3(4)-beta-glucanase:
1 800-2 700 U

endo-1,4-beta-xylanase:
2 600-3 900 U.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta-glucans), e.g.
containing more than 20 % wheat
and 20 % barley.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

30.6.2004 (f)

3.

1.

2. Recommended dose per kg of

complete feedingstuff:

100 BGU

130 EXU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans and arabinoxylans), e.g.
containing more than 30 % wheat
and 30 % barley, or 20 % rye.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
7
9

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Laying hens

—

600 BGU

800 EXU

Turkeys for
fattening

—

600 BGU

800 EXU

—

—

—

—

End of period of
authorisation

1.4.2004 (l)

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

3.

1.

600 BGU

800 EXU.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta-glucans), e.g.
containing more than 40 % wheat
and more than 30 % barley.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

1.4.2004 (l)

2. Recommended dose per kg of

complete feedingstuff:

600 BGU

800 EXU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta-glucans), e.g.
containing more than 30 % wheat or
more than 30 % rye.

C

5
0
/
8
0

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No
(or EC No)

14

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Preparation of
endo-1,4-beta-xylanase produced
by Aspergillus niger (CBS 520.94)
having a minimum activity of:

Chickens for
fattening

—

endo-1,4-beta-
xylanase: 300 U

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

End of period of
authorisation

30.6.2004 (f)

Solid form:

Endo-1,4-beta-xylanase:
600 U (21)/g

Liquid form:

Endo-1,4-beta-xylanase: 300 U/ml

2. Recommended dose per kg of

complete feedingstuff:

endo-1,4-beta-xylanase:
300-600 U.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans), e.g. containing more
than 50 % wheat.

15

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Preparation of endo-1,3(4)-beta-
glucanase produced by Trichoderma
viride (CBS 517.94) having a
minimum activity of:

Chickens for
fattening

—

endo-1,3(4)-beta-
glucanase: 325 U

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

30.6.2004 (f)

Solid form:

Endo-1,3(4)-beta-glucanase:
650 U (22)/g

Liquid form:

Endo-1,3(4)-beta-glucanase:
325 U/ml

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase:
325-650 U.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans), e.g. containing more
than 50 % barley.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
8
1

No
(or EC No)

16

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Endo-1,4-beta-
glucanase
EC 3.2.1.4

Chickens for
fattening

Preparation of
endo-1,4-beta-glucanase produced
by Trichoderma longibrachiatum (IMI
SD 142) having a minimum
activity of:
Liquid form: 2 000 CU (23)/ml

—

250 CU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:
500-1 000 CU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans), e.g. containing more
than 40 % barley.

End of period of
authorisation

30.6.2004 (f)

Laying hens

—

250 CU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

30.6.2004 (f)

2. Recommended dose per kg of

complete feedingstuff:
500-1 000 CU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans), e.g. containing more
than 40 % barley.

C

5
0
/
8
2

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Piglets

Four
months

250 CU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.
500-1 000 CU.

2. Recommended dose per kg of

complete feedingstuff:
500-1 000 CU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans), e.g. containing more
than 40 % barley.

End of period of
authorisation

30.6.2004 (f)

Pigs for
fattening

—

250 CU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

30.6.2004 (f)

2. Recommended dose per kg of

complete feedingstuff:
500-1 000 CU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans), e.g. containing more
than 40 % barley.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
8
3

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Chickens for
fattening

Preparation of
endo-1,4-beta-glucanase produced
by Trichoderma longibrachiatum (IMI
SD 142) having a minimum
activity of:
Solid form: 2 000 CU (23)/g

—

250 CU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:
500-1 000 CU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans), e.g. containing more
than 40 % barley.

End of period of
authorisation

17.7.2004 (m)

Laying hens

—

250 CU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

17.7.2004 (m)

2. Recommended dose per kg of

complete feedingstuff:
500-1 000 CU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans), e.g. containing more
than 40 % barley.

Piglets

Four
months

250 CU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

17.7.2004 (m)

2. Recommended dose per kg of

complete feedingstuff:
500-1 000 CU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans), e.g. containing more
than 40 % barley.

C

5
0
/
8
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

End of period of
authorisation

Pigs for
fattening

—

250 CU

—

1. 1. In the directions for use of the

17.7.2004 (m)

additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:
500-1 000 CU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans), e.g. containing more
than 40 % barley.

17

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Chickens for
fattening

Preparation of
endo-1,4-beta-xylanase produced
by Trichoderma longibrachiatum (IMI
SD 135) having a minimum
activity of:
Liquid form: 6 000 EPU (24)/ml

—

750 EPU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

30.6.2004 (f)

2. Recommended dose per kg of

complete feedingstuff: 1 500-3 000
EPU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans), e.g. containing more
than 40 % wheat.

Laying hens

—

750 EPU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

30.6.2004 (p)

2. Recommended dose per kg of

complete feedingstuff: 1 500-3 000
EPU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans), e.g. containing more
than 40 % wheat.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
8
5

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Piglets

Four
months

750 EPU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff: 1 500-3 000
EPU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans), e.g. containing more
than 40 % wheat.

End of period of
authorisation

30.6.2004 (f)

Pigs for
fattening

—

750 EPU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

30.6.2004 (f)

2. Recommended dose per kg of

complete feedingstuff: 1 500-3 000
EPU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans), e.g. containing more
than 40 % wheat.

Chickens for
fattening

Preparation of
endo-1,4-beta-xylanase produced
by Trichoderma longibrachiatum (IMI
SD 135) having a minimum
activity of:
Solid form: 6 000 EPU (24)/g

—

750 EPU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

17.7.2004 (m)

2. Recommended dose per kg of

complete feedingstuff: 1 500-3 000
EPU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans), e.g. containing more
than 40 % wheat.

C

5
0
/
8
6

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Laying hens

—

750 EPU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

End of period of
authorisation

17.7.2004 (m)

2. Recommended dose per kg of

complete feedingstuff:
1 500-3 000 EPU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans), e.g. containing more
than 40 % wheat.

Piglets

Four
months

750 EPU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

17.7.2004 (m)

2. Recommended dose per kg of

complete feedingstuff:
1 500-3 000 EPU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans), e.g. containing more
than 40 % wheat.

Pigs for
fattening

—

750 EPU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

17.7.2004 (m)

2. Recommended dose per kg of

complete feedingstuff:
1 500-3 000 EPU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans), e.g. containing more
than 40 % wheat.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
8
7

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Turkeys for
fattening

—

750 EPU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

End of period of
authorisation

17.7.2004 (m)

2. Recommended dose per kg of

complete feedingstuff:
1 500-3 000 EPU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans), e.g. containing more
than 35 % wheat.

18

19

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Preparation of
endo-1,3(4)-beta-glucanase pro-
duced by Aspergillus niger (MUCL
39199) having a minimum activity
of:
Solid form: 2 000 AGL (25)/g

Liquid form: 500 AGL/ml

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Preparation of
endo-1,3(4)-beta-glucanase pro-
duced by Aspergillus niger (MUCL
39199) having a minimum activity
of:
Solid form: 1 500 AGL (25)/g

Liquid form: 200 AGL/g

Chickens for
fattening

—

100 AGL

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

30.6.2004 (f)

2. Recommended dose per kg of

complete feedingstuff: 100 AGL.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans), e.g. containing more
than 40 % barley and 20 % wheat.

Chickens for
fattening

—

25 AGL

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

30.6.2004 (f)

2. Recommended dose per kg of

complete feedingstuff: 25-100 AGL.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta- glucans), e.g. containing more
than 50 % barley.

C

5
0
/
8
8

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

End of period of
authorisation

30.6.2004 (f)

No
(or EC No)

20

21

22

Endo-1,4-beta-xyla-
nase
EC 3.2.1.8

Preparation of
endo-1,4-beta-xylanase produced
by Trichoderma longibrachiatum
(MUCL 39203) having a minimum
activity of:
Solid form: 2 000 AXC (26)/g

Liquid form: 500 AXC/ml

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Preparation of
endo-1,4-beta-xylanase produced
by Trichoderma longibrachiatum
(MUCL 39203) having a minimum
activity of:
Solid form: 1 500 AXC (26)/g

Liquid form: 200 AXC/g

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Preparation of
endo-1,3(4)-beta-glucanase pro-
duced by Trichoderma
longibrachiatum (CNCM MA 6-10
W) having a minimum activity of:
Solid form: 70 000 BGN (27)/g

Liquid form: 14 000 BGN/ml

Chickens for
fattening

—

100 AXC

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff: 100 AXC.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans), e.g. containing more
than 40 % wheat or rye.

Chickens for
fattening

—

25 AXC

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

30.6.2004 (f)

2. Recommended dose per kg of

complete feedingstuff: 25-100 AXC.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans), e.g. containing more
than 50 % wheat.

Chickens for
fattening

—

1 050 BGN

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

30.6.2004 (f)

2. Recommended dose per kg of

complete feedingstuff: 2 800 BGN.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta- glucans), e.g. containing more
than 50 % barley.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
8
9

No
(or EC No)

23

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Preparation of
endo-1,4-beta-xylanase produced
by Trichoderma longibrachiatum
(CNCM MA 6-10 W) having a
minimum activity of:
Solid form: 70 000 IFP (28)/g

Liquid form: 7 000 IFP/ml

Chickens for
fattening

—

1 050 IFP

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff: 1 400 IFP.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans), e.g. containing more
than 56 % wheat.

End of period of
authorisation

30.6.2004 (f)

Turkeys for
fattening

—

700 IFP

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

28.2.2005 (q)

2. Recommended dose per kg of

complete feedingstuff: 1 400 IFP.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans), e.g. containing more
than 40 % wheat.

Laying hens

—

840 IFP

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

28.2.2005 (q)

2. Recommended dose per kg of
complete feedingstuff: 840 IFP.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans), e.g. containing more
than 40 % wheat.

C

5
0
/
9
0

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No
(or EC No)

24

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Preparation of
endo-1,4-beta-xylanase and
endo-1,3(4)-beta-glucanase pro-
duced by Aspergillus niger (CNCM
I-1517) having a minimum activity
of:
28 000 QXU (29)/g
140 000 QGU (30)/g

Chickens for
fattening

—

420 QXU

1 120 QXU

1.

2 100 QGU

5 600 QGU

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

Laying hens

—

560 QXU

2 800 QGU

—

—

2. Recommended dose per kg of

complete feedingstuff:

560 QXU

2 800 QGU.

3.

1.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta-glucans), e.g.
containing more than 30 % wheat
and 30 % barley.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

560 QXU

2 800 QGU

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta-glucans), e.g.
containing more than 20 % wheat
and/or barley.

End of period of
authorisation

30.6.2004 (f)

1.10.2006 (x)

Turkeys for
fattening

—

280 QXU

840 QXU

1.

1 460 QGU

4 200 QGU

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

28.2.2007 (ab)

2. Recommended dose per kg of

complete feedingstuff:

560 QXU

2 800 QGU

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta-glucans), e.g.
containing more than 20 % wheat
and/or barley.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
9
1

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

No
(or EC No)

25

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Preparation of
endo-1,3(4)-beta-glucanase and
endo-1,4-beta-xylanase produced
by Aspergillus niger (NRRL 25541)
having a minimum activity of:

Endo-1,3(4)-beta-glucanase:
1 100 U (31)/g

Endo-1,4-beta-xylanase:
1 600 U (32)/g

Chickens for
fattening

—

endo-1,3(4)-beta-
glucanase: 138 U

endo-1,4-beta-
xylanase: 200 U

Laying hens

—

endo-1,3(4) -beta-gluc-
anase: 138 U

endo-1,4-beta-
xylanase: 200 U

—

—

—

—

End of period of
authorisation

30.6.2004 (f)

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

3.

1.

endo-1,3(4)-beta-glucanase: 138 U

endo-1,4-beta-xylanase: 200 U.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans and arabinoxylans), e.g.
containing more than 50 % barley or
30 % wheat and 30 % maize.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

30.6.2004 (f)

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase: 138 U

endo-1,4-beta-xylanase: 200 U.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta-glucans), e.g.
containing more than 50 % barley or
30 % wheat and 30 % maize.

C

5
0
/
9
2

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No
(or EC No)

26

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Preparation of
endo-1,3(4)-beta-glucanase pro-
duced by Trichoderma reesei (CBS
526.94) having a minimum
activity of:
Solid form: 350 000 BU (33)/g

Liquid form: 50 000 BU/g

Chickens for
fattening

—

23 000 BU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:
23 000-50 000 BU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
glucans), e.g. containing more than
20 % barley or 30 % rye.

End of period of
authorisation

30.6.2004 (i)

Piglets

Four
months

26 000 BU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

30.6.2004 (i)

2. Recommended dose per kg of

complete feedingstuff:
26 000-35 000 BU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
glucans), e.g. containing more than
60 % barley or wheat.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
9
3

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

No
(or EC No)

27

End of period of
authorisation

30.6.2004 (i)

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Preparation of
endo-1,4-beta-xylanase produced
by Trichoderma reesei (CBS 529.94)
and endo-1,3(4)-beta-glucanase
produced by Trichoderma reesei
(CBS 526.94) having minimum
activities of:

Solid form:
200 000 BXU (34)/g
200 000 BU (33)/g

Liquid form:

30 000 BXU/g

30 000 BU/g

Chickens for
fattening

—

2 500 BXU

—

1.

2 500 BU

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

Piglets

Two months 7 500 BXU

7 500 BU

—

—

2. Recommended dose per kg of

complete feedingstuff:

10 000 BXU

10 000 BU.

3.

1.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and glucans), e.g.
containing more than 40 % wheat or
30 % rye.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

28.2.2005 (q)

2. Recommended dose per kg of

complete feedingstuff:

7 500-15 000 BXU

7 500-15 000 BU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans and arabinoxylans), e.g.
containing more than 50 % wheat.

C

5
0
/
9
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

28

3-Phytase
EC 3.1.3.8

Preparation of 3-phytase produced
by Trichoderma reesei (CBS 528.94)
having a minimum activity of:
Solid form: 5 000 PPU (35)/g

Liquid form: 1 000 PPU/g

Piglets

Four
months

250 PPU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:
500-750 PPU.

3.

For use in compound feed rich in
phytates, e.g. containing more than
50 % cereals (corn, barley, wheat),
tapioca, oilseeds and pulses.

End of period of
authorisation

30.6.2004 (i)

Pigs for
fattening

—

500 PPU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

30.6.2004 (i)

2. Recommended dose per kg of

complete feedingstuff:
500-750 PPU.

3.

For use in compound feed rich in
phytates, e.g. containing more than
50 % cereals (corn, barley, wheat),
tapioca, oilseeds and pulses.

Chickens for
fattening

—

500 PPU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

28.2.2005 (q)

2. Recommended dose per kg of

complete feedingstuff:
500-750 PPU.

3.

For use in compound feed containing
more than 0,22 % phytin bound
phosphorus.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
9
5

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

End of period of
authorisation

30.6.2004 (g)

Chickens for
fattening

—

endo-1,3(4)-beta-gluc-
anase: 250 U

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

No
(or EC No)

29

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Preparation of
endo-1,3(4)-beta-glucanase pro-
duced by Geosmithia emersonii (IMI
SD 133) having a minimum
activity of:

Endo-1,3(4)-beta-glucanase:
5 500 U (36)/g

30

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Preparation of
endo-1,3(4)-beta-glucanase and
endo-1,4-beta-xylanase produced
by Penicillium funiculosum (IMI SD
101) having a minimum activity
of:

Chickens for
fattening

—

endo-1,3(4)-beta-gluc-
anase: 100 U

endo-1,4-beta-
xylanase: 70 U

Powder form:

Endo-1,3(4)-beta-glucanase:
2 000 U (37)/g

Endo-1,4-beta-xylanase:
1 400 U (38)/g

Liquid form:

Endo-1,3(4)-beta-glucanase:
500 U/ml

Endo-1,4-beta-xylanase: 350 U/ml

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase:
250 U.

3.

1.

—

—

For use in compound feed rich in
non-starch polysaccharides, (mainly
beta-glucans), e.g. containing more
than 50 % barley.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

30.6.2004 (g)

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase: 100 U

endo-1,4-beta-xylanase: 70 U.

3.

For use in compound feed rich in
non-starch polysaccharides, (mainly
beta-glucans and arabinoxylans), e.g.
containing more than 50 % barley or
60 % wheat.

C

5
0
/
9
6

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Turkeys for
fattening

—

endo-1,3(4)-beta-
glucanase: 100 U

endo-1,4-beta-
xylanase: 70 U

Laying hens

—

endo-1,3(4)-beta-
glucanase: 100 U

endo-1,4-beta-
xylanase: 70 U

—

—

—

—

End of period of
authorisation

28.2.2005 (q)

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase:
100 U

endo-1,4-beta-xylanase: 70 U.

3.

1.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans and arabinoxylans), e.g.
containing more than 50 % wheat.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

28.2.2005 (q)

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase: 100 U

endo-1,4-beta-xylanase: 70 U.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans and arabinoxylans), e.g.
containing more than 60 % barley or
30 % wheat.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
9
7

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Pigs for
fattening

—

endo-1,3(4)-beta-
glucanase: 100 U

endo-1,4- beta-
xylanase: 70 U

—

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

End of period of
authorisation

28.2.2005 (q)

31

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Preparation of
endo-1,4-beta-xylanase produced
by Trichoderma longibrachiatum
(CBS 614.94) having a minimum
activity of:
Solid form: 300 EU (39)/g

Liquid form: 1 000 EU/g

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase: 100 U

endo-1,4-beta-xylanase: 70 U.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans and arabinoxylans), e.g.
containing more than 50 % barley or
60 % wheat.

Chickens for
fattening

—

600 EU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

30.6.2004 (g)

2. Recommended dose per kg of
complete feedingstuff: 600 EU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans), e.g. containing more
than 60 % wheat.

Laying hens

—

300 EU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

30.6.2004 (g)

2. Recommended dose per kg of
complete feedingstuff: 600 EU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans), e.g. containing more
than 60 % wheat.

C

5
0
/
9
8

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

No
(or EC No)

32

End of period of
authorisation

30.6.2004 (h)

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Preparation of
endo-1,3(4)-beta-glucanase pro-
duced by Trichoderma
longibrachiatum (ATCC 2106)
having a minimum activity of:

Endo-1,3(4)-beta-glucanase:
200 U (22)/ml

Preparation of
endo-1,3(4)-beta-glucanase pro-
duced by Trichoderma
longibrachiatum (ATCC 2106)
having a minimum activity of:

Endo-1,3(4)-beta-glucanase:
1 200 U (22)/ml

Chickens for
fattening

—

endo-1,3(4)-beta-
glucanase: 100 U

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:
endo-1,3(4)-beta-glucanase:
100 U.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans), e.g. containing more
than 30 % barley.

Piglets

Four
months

endo-1,3(4)-beta-
glucanase: 400 U

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

30.6.2004 (h)

2. Recommended dose per kg of

complete feedingstuff:
endo-1,3(4)-beta-glucanase:
400 U.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans), e.g. containing more
than 55 % barley.

Pigs for
fattening

—

endo-1,3(4)-beta-
glucanase: 500 U

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting

30.6.2004 (h)

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase:
500 U.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans), e.g. containing more
than 70 % barley.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
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U
n
o
n

i

C

5
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/
9
9

No
(or EC No)

33

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Preparation of
endo-1,4-beta-xylanase produced
by Trichoderma longibrachiatum
(ATCC 2105) having a minimum
activity of:

Powder form:

Endo-1,4-beta-xylanase:
2 000 U (40)/g

Liquid form:

Endo-1,4-beta-xylanase:
5 000 U/ ml

Chickens for
fattening

—

endo-1,4-beta-
xylanase: 500 U

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,4-beta-xylanase:
500-2 500 U.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans), e.g. containing more
than 55 % wheat or 60 % rye.

End of period of
authorisation

30.6.2004 (h)

Laying hens

—

endo-1,4-beta-
xylanase: 2 000 U

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

30.6.2004 (h)

2. Recommended dose per kg of

complete feedingstuff:

endo-1,4-beta-xylanase: 2 000 U.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans), e.g. containing more
than 35 % wheat.

Preparation of
endo-1,4-beta-xylanase produced
by Trichoderma longibrachiatum
(ATCC 2105) having a minimum
activity of:

Powder form:

Endo-1,4-beta-xylanase:
4 000 U (40)/g

Liquid form:

Endo-1,4-beta-xylanase:
10 000 U/ml

Piglets

Four
months

endo-1,4-beta-
xylanase: 5 000 U

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

30.6.2004 (h)

2. Recommended dose per kg of

complete feedingstuff:

endo-1,4-beta-xylanase: 5 000 U.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans), e.g. containing more
than 45 % wheat.

C

5
0
/
1
0
0

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
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r
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p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

End of period of
authorisation

30.6.2004 (h)

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Preparation of
endo-1,4-beta-xylanase produced
by Trichoderma longibrachiatum
(ATCC 2105) having a minimum
activity of:

Powder form:

Endo-1,4-beta-xylanase:
4 000 U (40)/g

Liquid form:

Endo-1,4-beta-xylanase:
8 000 U/ml

Preparation of endo-1,3
(4)-beta-glucanase and
endo-1,4-beta-xylanase produced
by Aspergillus niger (NRRL 25541)
and of alpha-amylase produced by
Aspergillus oryzae (ATCC 66222)
having a minimum activity of:

Endo-1,3(4)-beta-glucanase:
275 U (31)/g

Endo-1,4-beta-xylanase:
400 U (32)/g
Alpha-amylase: 3 100 U (41)/g

34

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Alpha-amylase
EC 3.2.1.1

Pigs for
fattening

—

endo-1,4-beta-
xylanase: 4 000 U

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

Piglets

Four
months

endo-1,3(4)-beta-
glucanase: 165 U

endo-1,4-beta-
xylanase: 240 U

alpha-amylase:
1 860 U

—

—

—

2. Recommended dose per kg of

complete feedingstuff:

3.

1.

endo-1,4-beta-xylanase: 4 000 U.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans), e.g. containing more
than 35 % wheat.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
the stability to pelleting.

26.7.2004 (j)

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase: 165 U

endo-1,4-beta-xylanase: 240 U

alpha-amylase: 1 860 U.

3.

For use in compound feed containing
cereals rich in starch and non-starch
polysaccharides (mainly arabinoxylans
and beta-glucans), e.g. containing
more than 45 % barley and 10 %
wheat or 10 % maize.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
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a
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U
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o
n

i

C

5
0
/
1
0
1

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

No
(or EC No)

35

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Endo-1,4-beta-
xylanase
EC 3.2.1.8

36

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Laying hens

—

endo-1,3(4)-beta-
glucanase: 80 U

endo-1,4-beta-
xylanase: 180 U

Chickens for
fattening

—

endo-1,3(4)-beta-
glucanase: 300 U

endo-1,4-beta-
xylanase: 300 U

—

—

—

—

Preparation of
endo-1,3(4)-beta-glucanase pro-
duced by Trichoderma
longibrachiatum (ATCC 2106) and
endo-1,4-beta- xylanase produced
by Trichoderma longibrachiatum
(ATCC 2105) having a minimum
activity of:

Endo-1,3(4)-beta-glucanase:
80 U (22)/g

Endo-1,4-beta-xylanase: 180
U (40)/g

Preparation of
endo-1,3(4)-beta-glucanase pro-
duced by Trichoderma
longibrachiatum (ATCC 2106) and
endo-1,4-beta-xylanase produced
by Trichoderma longibrachiatum (IMI
SD 135) having a minimum
activity of:

Endo-1,3(4)-beta-glucanase:
300 U (22)/g

Endo-1,4-beta-xylanase:
300 U (40)/g

End of period of
authorisation

26.7.2004 (j)

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

3.

1.

endo-1,3(4)-beta-glucanase: 80 U

endo-1,4-beta-xylanase: 180 U.

For use in compound feed rich in
non-starch polysaccharides, (mainly
beta-glucans and arabinoxylans), e.g.
containing more than 60 % barley.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

26.7.2004 (j)

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase: 300 U

endo-1,4-beta-xylanase: 300 U.

3.

For use in compound feed rich in
non-starch polysaccharides, (mainly
beta-glucans and arabinoxylans), e.g.
containing more than 40 % barley.

C

5
0
/
1
0
2

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Laying hens

—

endo-1,3(4)-beta-
glucanase: 300 U

endo-1,4-beta-
xylanase: 300 U

37

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Subtilisin
EC 3.4.21.62

Preparation of
endo-1,4-beta-xylanase produced
by Trichoderma longibrachiatum
(ATCC 2105) and subtilisin
produced by Bacillus subtilis (ATCC
2107), with a minimum activity
of:

Endo-1,4-beta-xylanase:
2 500 U (40)/g
Subtilisin: 800 U (42)/g

Chickens for
fattening

—

endo-1,4-beta-
xylanase: 500 U

subtilisin: 160 U

—

—

—

—

End of period of
authorisation

26.7.2004 (j)

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

3.

1.

endo-1,3(4)-beta-glucanase: 300 U

endo-1,4-beta-xylanase: 300 U.

For use in compound feed rich in
non-starch polysaccharides, (mainly
beta-glucans and arabinoxylans), e.g.
containing more than 35 % barley.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

26.7.2004 (j)

2. Recommended dose per kg of

complete feedingstuff:

endo-1,4-beta-xylanase:
500-2 500 U

subtilisin: 160-800 U.

3.

For use in compound feed e.g.
containing more than 65 % wheat.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
1
0
3

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Turkeys

—

endo-1,4-beta-
xylanase: 825 U

subtilisin: 265 U

38

39

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Subtilisin
EC 3.4.21.62

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Preparation of
endo-1,4-beta-xylanase produced
by Trichoderma longibrachiatum
(ATCC 2105) and subtilisin
produced by Bacillus subtilis (ATCC
2107) having a minimum activity
of:

Endo-1,4-beta-xylanase:
5 000 U (40)/g
Subtilisin: 500 U (42)/g

Preparation of
endo-1,3(4)-beta-glucanase
produced by Trichoderma
longibrachiatum (ATCC 2106) and
endo-1,4-beta-xylanase produced
by Trichoderma longibrachiatum
(ATCC 2105) having a minimum
activity of:

Endo-1,3(4)-beta-glucanase:
400 U (22)/g

Endo-1,4-beta-xylanase:
400 U (40)/g

Piglets

Four
months

endo-1,4-beta-
xylanase: 5 000 U

subtilisin: 500 U

Pigs for
fattening

—

endo-1,3(4)-beta-
glucanase: 400 U

endo-1,4-beta-xyla-
nase: 400 U

—

—

—

—

—

—

End of period of
authorisation

26.7.2004 (j)

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,4-beta-xylanase:
825-2 500 U

subtilisin: 265-800 U.

For use in compound feed e.g.
containing more than 45 % wheat.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

26.7.2004 (j)

3.

1.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,4-beta- xylanase: 5 000 U

3.

1.

subtilisin: 500 U.

For use in compound feed e.g.
containing more than 40 % wheat.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

26.7.2004 (j)

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase: 400 U

endo-1,4-beta-xylanase: 400 U.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans and arabinoxylans) e.g.
containing more than 65 % barley.

C

5
0
/
1
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No
(or EC No)

40

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Subtilisin
EC 3.4.21.62

41

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Subtilisin
EC 3.4.21.62

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Chickens for
fattening

—

endo-1,3(4)-beta-gluc-
anase: 30 U

endo-1,4-beta-
xylanase: 90 U

subtilisin: 240 U

Chickens for
fattening

—

endo-1,3(4)-beta-gluc-
anase: 25 U

endo-1,4-beta-
xylanase: 625 U

subtilisin: 200 U

Preparation of
endo-1,3(4)-beta-glucanase pro-
duced by Trichoderma
longibrachiatum (ATCC 2106),
endo-1,4-beta- xylanase produced
by Trichoderma longibrachiatum
(ATCC 2105) and subtilisin
produced by Bacillus subtilis (ATCC
2107) having a minimum activity
of:

Endo-1,3(4)-beta-glucanase:
100 U (22)/g

Endo-1,4-beta-xylanase:
300 U (40)/g
Subtilisin: 800 U (42)/g

Preparation of
endo-1,3(4)-beta-glucanase pro-
duced by Trichoderma
longibrachiatum (ATCC 2106),
endo-1,4-beta- xylanase produced
by Trichoderma longibrachiatum
(ATCC 2105) and subtilisin
produced by Bacillus subtilis (ATCC
2107) having a minimum activity
of:

Endo-1,3(4)-beta-glucanase:
100 U (22)/g

Endo-1,4-beta-xylanase:
2 500 U (40)/g
Subtilisin: 800 U (42)/g

—

—

—

—

—

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)- beta-glucanase: 30-100
U

endo-1,4-beta-xylanase: 90-300 U

subtilisin: 240-800 U.

3.

For use in compound feed e.g.
containing more than 60 % barley.

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase:
25-100 U

endo-1,4-beta-xylanase:
625-2 500 U

subtilisin: 200-800 U.

3.

For use in compound feed e.g.
containing more than 30 % wheat
and 10 % barley.

End of period of
authorisation

26.7.2004 (j)

26.7.2004 (j)

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
1
0
5

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Laying hens

—

endo-1,3(4)-beta-gluc-
anase: 100 U

endo-1,4-beta-
xylanase: 2 500 U

subtilisin: 800 U

Piglets

Four
months

endo-1,4-beta-
xylanase: 4 000 U

—

—

—

—

42

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Preparation of
endo-1,4-beta-xylanase produced
by Trichoderma longibrachiatum (IMI
SD 135) having a minimum
activity of:

Solid form:

Endo-1,4-beta-xylanase:
4 000 U (40)/g

Characteristics of the authorised
preparation:

Endo-1,4-beta-xylanase: 1,99 %

Wheat: 97,7 %

Calcium propionate: 0,3 %

Lecithin: 0,01 %

End of period of
authorisation

26.7.2004 (j)

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase: 100 U

endo-1,4-beta-xylanase: 2 500 U

subtilisin: 800 U.

For use in compound feed e.g.
containing more than 50 % wheat
and 25 % barley.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

26.7.2004 (j)

3.

1.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,4-beta-xylanase: 4 000 U.

3.

For use in compound feed rich in
non-starch polysaccharides, (mainly
arabinoxylans), e.g. containing more
than 60 % wheat.

C

5
0
/
1
0
6

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Pigs for
fattening

—

endo-1,4-beta-xyla-
nase: 4 000 U

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

End of period of
authorisation

17.7.2004 (m)

Piglets

Four
months

endo-1,4-beta-
xylanase: 3 975 U

endo-1,3(4)-beta-
glucanase: 125 U

alpha-amylase:
1 000 U

—

—

—

43

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Alpha-amylase
EC 3.2.1.1

Preparation of
endo-1,4-beta-xylanase produced
by Trichoderma longibrachiatum (IMI
SD 135),
endo-1,3(4)-beta-glucanase
produced by Trichoderma
longibrachiatum (ATCC 2106) and
alpha-amylase produced by Bacillus
amyloliquefaciens (DSM 9553)
having a minimum activity of:

Endo-1,4-beta-xylanase:
3 975 U (40)/g

Endo-1,3(4)-beta-glucanase:
125 U (22)/g
Alpha-amylase: 1 000 U (43)/g

2. Recommended dose per kg of

complete feedingstuff:

3.

1.

endo-1,4-beta-xylanase: 4 000 U.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans), e.g. containing more
than 60 % wheat.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

6.1.2004 (k)

2. Recommended dose per kg of

complete feedingstuff:

endo-1,4-beta-xylanase: 3 975 U

endo-1,3(4)-beta-glucanase: 125 U

alpha-amylase: 1 000 U.

3.

For use in compound feed containing
cereals rich in starch and non-starch
polysaccharides (mainly arabinoxylans
and beta-glucans), e.g. containing
more than 30 % wheat and 20 %
barley and 20 % rye.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
1
0
7

No
(or EC No)

44

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Alpha-amylase
EC 3.2.1.1

45

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Alpha-amylase
EC 3.2.1.1

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Piglets

Four
months

endo-1,3(4)-beta-
glucanase: 250 U

endo-1,4-beta-
xylanase: 400 U

alpha-amylase:
1 000 U

Piglets

Four
months

endo-1,3(4)-beta-
glucanase: 250 U

endo-1,4-beta-
xylanase: 400 U

alpha-amylase:
1 000 U

—

—

—

—

—

—

Preparation of
endo-1,3(4)-beta-glucanase
produced by Trichoderma
longibrachiatum (ATCC 2106) and
endo-1,4-beta-xylanase produced
by Trichoderma longibrachiatum
(ATCC 2105) and alpha-amylase
produced by Bacillus
amyloliquefaciens (DSM 9553)
having a minimum activity of:

Endo-1,3(4)-beta-glucanase:
250 U (22)/g

Endo-1,4-beta-xylanase:
400 U (40)/g
Alpha-amylase: 1 000 U (43)/g

Preparation of
endo-1,3(4)-beta-glucanase
produced by Trichoderma
longibrachiatum (ATCC 2106) and
endo-1,4-beta-xylanase produced
by Trichoderma longibrachiatum (IMI
SD 135) and alpha-amylase
produced by Bacillus
amyloliquefaciens (DSM 9553)
having a minimum activity of:

Endo-1,3(4)-beta-glucanase:
250 U (22)/g

Endo-1,4-beta-xylanase:
400 U (40)/g
Alpha-amylase: 1 000 U (43)/g

End of period of
authorisation

6.1.2004 (k)

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase: 250 U

endo-1,4-beta-xylanase: 400 U

alpha-amylase: 1 000 U.

For use in compound feed containing
cereals rich in starch and non-starch
polysaccharides (mainly arabinoxylans
and beta-glucans), e.g. containing
more than 50 % barley.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

6.1.2004 (k)

3.

1.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase: 250 U

endo-1,4-beta-xylanase: 400 U

alpha-amylase: 1 000 U.

3.

For use in compound feed containing
cereals rich in starch and non-starch
polysaccharides (mainly arabinoxylans
and beta-glucans), e.g. containing
more than 35 % barley.

C

5
0
/
1
0
8

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No
(or EC No)

46

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Polygalacturonase
EC 3.2.1.15

47

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Alpha-amylase
EC 3.2.1.1

Polygalacturonase
EC 3.2.1.15

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Pigs for
fattening

—

endo-1,3(4)-beta-
glucanase: 400 U

endo-1,4-beta-
xylanase: 400 U

polygalacturonase:
50 U

Piglets

Four
months

endo-1,3(4)-beta-
glucanase: 150 U

endo-1,4-beta-
xylanase: 4 000 U

alpha-amylase:
1 000 U

polygalacturonase:
25 U

—

—

—

—

—

—

—

Preparation of
endo-1,3(4)-beta-glucanase
produced by Trichoderma
longibrachiatum (ATCC 2106) and
endo-1,4-beta-xylanase produced
by Trichoderma longibrachiatum (IMI
SD 135) and polygalacturonase
produced by Aspergillus aculeatus
(CBS 589.94) having a minimum
activity of:

Endo-1,3(4)-beta-glucanase:
400 U (22)/g

Endo-1,4-beta-xylanase:
400 U (40)/g
Polygalacturonase: 50 U (44)/g

Preparation of
endo-1,3(4)-beta-glucanase
produced by Trichoderma
longibrachiatum (ATCC 2106),
endo-1,4-beta-xylanase produced
by Trichoderma longibrachiatum (IMI
SD 135), alpha-amylase produced
by Bacillus amyloliquefaciens (DSM
9553), polygalacturonase
produced by Aspergillus aculeatus
(CBS 589.94) having a minimum
activity of:

Endo-1,3(4)-beta-glucanase:
150 U (22)/g

Endo-1,4-beta-xylanase:
4 000 U (40)/g
Alpha-amylase: 1 000 U (43)/g
Polygalacturonase: 25 U (44)/g

End of period of
authorisation

6.1.2004 (k)

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase: 400 U

endo-1,4-beta-xylanase: 400 U

polygalacturonase: 50 U.

For use in compound feed containing
cereals rich in starch and non-starch
polysaccharides (mainly arabinoxylans
and beta-glucans), e.g. containing
more than 40 % barley.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

6.1.2004 (k)

3.

1.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase: 150 U

endo-1,4-beta-xylanase: 4 000 U

alpha-amylase: 1 000 U

polygalacturonase: 25 U.

3.

For use in compound feed containing
cereals rich in starch and non-starch
polysaccharides (mainly arabinoxylans
and beta-glucans), e.g. containing
more than 20 % barley and 35 %
wheat.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
1
0
9

No
(or EC No)

48

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Chickens for
fattening

—

10 KNU

17 FBG

Alpha-amylase
EC 3.2.1.1

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Preparation of alpha-amylase and
endo-1,3(4)-beta-glucanase pro-
duced by Bacillus amyloliquefaciens
(DSM 9553) having a minimum
activity of:

Coated form:
Alpha-amylase: 200 KNU (45)/g

Endo-1,3(4)-beta-glucanase:
350 FBG (9)/g

Liquid form:

Alpha-amylase: 130 KNU/ ml

Endo-1,3(4)-beta-glucanase:
225 FBG/ml

40 KNU

1.

70 FBG

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

20 KNU

35 FBG.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta-glucans), e.g.
containing more than 40 % barley.

End of period of
authorisation

1.4.2004 (l)

Turkeys for
fattening

—

40 KNU

70 FBG

80 KNU

1.

140 FBG

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

1.4.2004 (l)

2. Recommended dose per kg of

complete feedingstuff:

40 KNU

70 FBG.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta-glucans), e.g.
containing more than 40 % barley.

C

5
0
/
1
1
0

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No
(or EC No)

49

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Chickens for
fattening

—

endo-1,3(4)-beta-
glucanase: 150 U

endo-1,4-beta-xyla-
nase: 1 500 U

alpha-amylase: 500 U

bacillolysin: 800 U

polygalac-turonase:
50 U

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Alpha-amylase
EC 3.2.1.1

Bacillolysin
EC 3.4.24.28

Polygalacturonase
EC 3.2.1.15

Preparation of
endo-1,3(4)-beta-glucanase
produced by Trichoderma
longibrachiatum (ATCC 2106),
endo-1,4-beta-xylanase produced
by Trichoderma longibrachiatum (IMI
SD 135), alpha-amylase produced
by Bacillus amyloliquefaciens (DSM
9553), bacillolysin produced by
Bacillus amyloliquefaciens (DSM
9554) and polygalacturonase
produced by Aspergillus aculeatus
(CBS 589.94) having a minimum
activity of:

Endo-1,3(4)-beta-glucanase:
150 U (22)/g

Endo-1,4-beta-xylanase:
1 500 U (40)/g
Alpha-amylase: 500 U (43)/g
Bacillolysin: 800 U (42)/g
Polygalacturonase: 50 U (44)/g

Laying hens

—

endo-1,3(4)-beta-
glucanase: 150 U

endo-1,4-beta-
xylanase: 1 500 U

alpha-amylase: 500 U

bacillolysin: 800 U

polygalac- turonase:
50 U

—

—

—

—

—

—

—

—

—

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase: 150 U

endo-1,4-beta-xylanase: 1 500 U

alpha-amylase: 500 U

bacillolysin: 800 U

polygalacturonase: 50 U.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta-glucans), e.g.
containing more than 30 % wheat.

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase: 150 U

endo-1,4-beta-xylanase: 1 500 U

alpha-amylase: 500 U

bacillolysin: 800 U

polygalacturonase: 50 U.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta-glucans), e.g.
containing more than 30 % wheat.

End of period of
authorisation

17.7.2004 (m)

17.7.2004 (m)

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
1
1
1

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

50

6-Phytase
EC 3.1.3.26

Preparation of 6-phytase produced
by Aspergillus oryzae (DSM 11857)
having a minimum activity of:

Chickens for
fattening

—

250 FYT

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

End of period of
authorisation

17.7.2004 (m)

Coated form:
2 500 FYT (46)/g

Liquid form:

5 000 FYT/g

Laying hens

—

250 FYT

—

Turkeys for
fattening

—

250 FYT

—

2. Recommended dose per kg of

complete feedingstuff:

500-1 000 FYT.

3.

1.

For use in compound feed containing
more than 0,25 % phytin bound
phosphorus.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

17.7.2004 (m)

2. Recommended dose per kg of

complete feedingstuff:

500-1 000 FYT.

3.

1.

For use in compound feed containing
more than 0,25 % phytin bound
phosphorus.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

17.7.2004 (m)

2. Recommended dose per kg of

complete feedingstuff:

500-1 000 FYT.

3.

For use in compound feed containing
more than 0,25 % phytin bound
phosphorus.

C

5
0
/
1
1
2

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Piglets

Two months 500 FYT

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

End of period of
authorisation

17.7.2004 (m)

Pigs for
fattening

—

500 FYT

—

Sows

—

750 FYT

—

2. Recommended dose per kg of

complete feedingstuff:

500-1 000 FYT.

3.

1.

For use in compound feed containing
more than 0,25 % phytin bound
phosphorus.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

17.7.2004 (m)

2. Recommended dose per kg of

complete feedingstuff:

500-1 000 FYT.

3.

1.

For use in compound feed containing
more than 0,25 % phytin bound
phosphorus.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

1.2.2007 (aa)

2. Recommended dose per kg of

complete feedingstuff:

750-1 000 FYT

3.

For use in compound feed containing
more than 0,25 % phytin bound
phosphorus.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
1
1
3

No
(or EC No)

51

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Preparation of
endo-1,4-beta-xylanase produced
by Bacillus subtilis (LMG-S 15136)
having a minimum activity of:
100 IU (47)/g

Chickens for
fattening

—

10 IU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

10 IU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans), e.g. containing more
than 40 % wheat.

End of period of
authorisation

17.7.2004 (m)

Piglets

Two months 10 IU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

31.5.2005 (r)

Pigs for
fattening

—

10 IU

—

2. Recommended dose per kg of
complete feedingstuff: 10 IU.

3.

1.

For use in compound feed rich in
arabinoxylan, e.g. containing more
than 40 % wheat.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

1.2.2007 (aa)

2. Recommended dose per kg of
complete feedingstuff: 10 IU.

3.

For use in compound feed rich in
arabinoxylans e.g. minimum 40 %
wheat or barley.

C

5
0
/
1
1
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Preparation of
endo-1,4-beta-xylanase produced
by Bacillus subtilis (LMG S-15136)
having a minimum activity of:
Liquid: 100 IU (47)/ml

Chickens for
fattening

—

10 IU

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

End of period of
authorisation

1.1.2007 (y)

Preparation of
endo-1,4-beta-xylanase produced
by Bacillus subtilis (LMG S-15136)
having a minimum activity of:

Chickens for
fattening

Solid and liquid:
100 IU (47)/g or ml

—

10 IU

—

52

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Endo-1,4-beta-
glucanase
EC 3.2.1.4

Alpha-amylase
EC 3.2.1.1

Preparation of
endo-1,3(4)-beta-glucanase pro-
duced by Aspergillus aculeatus (CBS
589.94), endo-1,4-beta-glucanase
produced by Trichoderma
longibrachiatum (CBS 592.94) and
alpha-amylase produced by Bacillus
amyloliquefaciens (DSM 9553)
having a minimum activity of:

Chickens for
fattening

—

endo-1,3(4)-beta-gluc-
anase: 1 000 U

endo-1,4-beta-
glucanase: 12 000 U

alpha-amylase: 40 U

—

—

—

Liquid form:

Endo-1,3(4)-beta-glucanase:
10 000 U (48)/ml

Endo-1,4-beta-glucanase:
120 000 U (49)/ml
Alpha-amylase: 400 U (50)/ml

2. Recommended dose per kg of
complete feedingstuff: 10 IU.

3.

1.

For use in compound feed rich in
arabinoxylan, e.g. containing
minimum 40 % wheat or barley.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

1.1.2007 (y)

2. Recommended dose per kg of
complete feedingstuff: 10 IU.

3.

1.

For use in compound feed rich in
arabinoxylan, e.g. containing
minimum 40 % wheat or barley.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

17.7.2004 (m)

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase:
1 000-2 000 U

endo-1,4-beta-glucanase: 12 000-24
000 U

alpha-amylase: 40-80 U.

3.

For use in compound feed rich in
non starch polysaccharides (mainly
arabinoxylans and beta-glucans) e.g.
containing more than 20 % wheat
and 15 % sorghum and 5 % maize.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
1
1
5

No
(or EC No)

53

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Endo-1,4-beta-
glucanase
EC 3.2.1.4

Alpha-amylase
EC 3.2.1.1

Bacillolysin
EC 3.4.24.28

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Preparation of
endo-1,3(4)-beta-glucanase
produced by Aspergillus aculeatus
(CBS 589.94),
endo-1,4-beta-glucanase produced
by Trichoderma longibrachiatum
(CBS 592.94), alpha-amylase
produced by Bacillus
amyloliquefaciens (DSM 9553),
bacillolysin produced by Bacillus
amyloliquefaciens (DSM 9554) and
endo-1,4-beta-xylanase produced
by Trichoderma viride (NIBH FERM
BP 4842) having a minimum
activity of:

Endo-1,3(4)-beta-glucanase:
2 350 U (48)/g

Endo-1,4-beta-glucanase:
4 000 U (49)/g
Alpha-amylase: 400 U (51)/g
Bacillolysin: 450 U (52)/g

Endo-1,4-beta-xylanase:
20 000 U (53)/g

Piglets

Two months

endo-1,3(4)-beta-
glucanase: 2 350 U

endo-1,4-beta-
glucanase: 4 000 U

alpha-amylase: 400 U

bacillolysin: 450 U

endo-1,4-beta-
xylanase: 20 000 U

—

—

—

—

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase:
2 350 U

endo-1,4-beta-glucanase: 4 000 U

alpha-amylase: 400 U

bacillolysin: 450 U

endo-1,4-beta-xylanase:
20 000 U.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans and arabinoxylans), e.g.
containing more than 25 % barley
and 20 % maize.

End of period of
authorisation

23.11.2004 (o)

C

5
0
/
1
1
6

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Chickens for
fattening

—

endo-1,3(4)-beta-
glucanase: 1 175 U

endo-1,4-beta-
glucanase: 2 000 U

alpha-amylase: 200 U

bacillolysin: 225 U

endo-1,4-beta-
xylanase: 10 000 U

Chickens for
fattening

—

endo-1,3(4)-beta-
glucanase: 1 000 U

endo-1,4-beta-
glucanase: 12 000 U

alpha-amylase: 40 U

endo-1,4-beta-
xylanase: 21 000 U

54

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Endo-1,4-beta-
glucanase
EC 3.2.1.4

Alpha-amylase
EC 3.2.1.1

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Preparation of
endo-1,3(4)-beta-glucanase pro-
duced by Aspergillus aculeatus (CBS
589.94), endo-1,4-beta-glucanase
produced by Trichoderma
longibrachiatum (CBS 592.94),
alpha-amylase produced by Bacillus
amyloliquefaciens (DSM 9553) and
endo-1,4-beta-xylanase produced
by Trichoderma viride (NIBH FERM
BP 4842) having a minimum
activity of:

Endo-1,3(4)-beta-glucanase:
10 000 U (48)/g

Endo-1,4-beta-glucanase:
120 000 U (49)/g
Alpha-amylase: 400 U (51)/g

Endo-1,4-beta-xylanase:
210 000 U (53)/g

—

—

—

—

—

—

—

—

—

End of period of
authorisation

23.11.2004 (o)

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase:
1 175-2 350 U

endo-1,4-beta-glucanase:
2 000-4 000 U

alpha-amylase: 200-400 U

bacillolysin: 225-450 U

endo-1,4-beta-xylanase:
10 000-20 000 U.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans and arabinoxylans), e.g.
containing more than 45 % wheat.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

23.11.2004 (o)

3.

1.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase:
1 000-2 000 U

endo-1,4-beta-glucanase:
12 000-24 000 U

alpha-amylase: 40-80 U

endo-1,4-beta-xylanase:
21 000-42 000 U.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans and arabinoxylans), e.g.
containing more than 45 % wheat.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
1
1
7

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Turkeys for
fattening

—

endo-1,3(4)-beta-
glucanase: 500 U

endo-1,4-beta-
glucanase: 6 000 U

alpha-amylase: 20 U

endo-1,4-beta-
xylanase: 10 500 U

Piglets

Two months

endo-1,3(4)-beta-
glucanase: 1 500 U

endo-1,4-beta-
glucanase: 2 500 U

alpha-amylase: 270 U

bacillolysin: 225 U

55

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Endo-1,4-beta-
glucanase
EC 3.2.1.4

Alpha-amylase
EC 3.2.1.1

Bacillolysin
EC 3.4.24.28

Preparation of
endo-1,3(4)-beta-glucanase pro-
duced by Aspergillus aculeatus (CBS
589.94), endo-1,4-beta-glucanase
produced by Trichoderma
longibrachiatum (CBS 592.94),
alpha-amylase produced by Bacillus
amyloliquefaciens (DSM 9553) and
bacillolysin produced by Bacillus
amyloliquefaciens (DSM 9554)
having a minimum activity of:

Endo-1,3(4)-beta-glucanase:
3 000 U (48)/g

Endo-1,4-beta-glucanase:
5 000 U (49)/g
Alpha-amylase: 540 U (51)/g
Bacillolysin: 450 U (52)/g

—

—

—

—

—

—

—

—

End of period of
authorisation

13.10.2005 (t)

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

2. Recommended dose per kilogram of

complete feedingstuff:

endo-1,3(4)-beta-glucanase:
500-1 500 U

endo-1,4-beta-glucanase:
6 000-18 000 U

alpha-amylase: 20-60 U

endo-1,4-beta-xylanase:
10 500-31 500 U

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans and arabinoxylans), e.g.
containing more than 30 % wheat.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

23.11.2004 (o)

3.

1.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase:
1 500-3 000 U

endo-1,4-beta-glucanase:
2 500-5 000 U

alpha-amylase: 270-540 U

bacillolysin: 225-450 U.

3.

For use in compound feed rich in
starch and non-starch
polysaccharides, e.g. containing more
than 35 % wheat and 15 % barley.

C

5
0
/
1
1
8

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Pigs for
fattening

—

endo-1,3(4)-beta-
glucanase: 1 500 U

endo-1,4-beta-
glucanase: 2 500 U

alpha-amylase: 270 U

bacillolysin: 225 U

Chickens for
fattening

—

endo-1,3(4)-beta-
glucanase: 1 500 U

endo-1,4-beta-
glucanase: 2 500 U

alpha-amylase: 270 U

bacillolysin: 225 U

—

—

—

—

—

—

—

—

End of period of
authorisation

23.11.2004 (o)

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase:
1 500-3 000 U

endo-1,4-beta-glucanase:
2 500-5 000 U

alpha-amylase: 270-540 U

bacillolysin: 225-450 U.

For use in compound feed rich in
starch and non-starch
polysaccharides, e.g. containing more
than 50 % barley.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

23.11.2004 (o)

3.

1.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase:
1 500-3 000 U

endo-1,4-beta-glucanase:
2 500-5 000 U

alpha-amylase: 270-540 U

bacillolysin: 225-450 U.

3.

For use in compound feed rich in
starch and non-starch
polysaccharides, e.g. containing more
than 50 % maize or 50 % wheat.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
1
1
9

No
(or EC No)

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Laying hens

—

endo-1,3(4)-beta-
glucanase: 1 500 U

endo-1,4-beta-
glucanase: 2 500 U

alpha-amylase: 270 U

bacillolysin: 225 U

Chickens for
fattening

—

endo-1,3(4)-beta-
glucanase: 6 000 U

Uendo-1,4-beta-
glucanase: 3 500 U

alpha-amylase:
1 400 U

bacillolysin: 450 U

56

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Endo-1,4-beta-
glucanase
EC 3.2.1.4

Alpha-amylase
EC 3.2.1.1

Bacillolysin
EC 3.4.24.28

Preparation of
endo-1,3(4)-beta-glucanase pro-
duced by Aspergillus aculeatus (CBS
589.94), endo-1,4-beta-glucanase
produced by Trichoderma
longibrachiatum (CBS 592.94),
alpha-amylase produced by Bacillus
amyloliquefaciens (DSM 9553) and
bacillolysin produced by Bacillus
amyloliquefaciens (DSM 9554)
having a minimum activity of:

Endo-1,3(4)-beta-glucanase: 6 000
U (48)/g

Endo-1,4-beta-glucanase: 3 500
U (49)/g
Alpha-amylase: 1 400 U (51)/g
Bacillolysin: 450 U (52)/g

—

—

—

—

—

—

—

—

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase:
1 500-3 000 U

endo-1,4-beta-glucanase:
2 500-5 000 U

alpha-amylase: 270-540 U

bacillolysin: 225-450 U.

3.

1.

For use in compound feed rich in
starch and non-starch
polysaccharides, e.g. containing more
than 40 % maize and 10 % rye.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase:
6 000 U

endo-1,4-beta-glucanase: 3 500 U

alpha-amylase: 1 400 U

bacillolysin: 450 U.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
arabinoxylans and beta-glucans), e.g.
containing more than 40 % barley.

End of period of
authorisation

23.11.2004 (o)

23.11.2004 (o)

C

5
0
/
1
2
0

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No
(or EC No)

57

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Endo-1,4-beta-
glucanase
EC 3.2.1.4

Alpha-amylase
EC 3.2.1.1

Bacillolysin
EC 3.4.24.28

58

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Endo-1,4-beta-
glucanase
EC 3.2.1.4

Alpha-amylase
EC 3.2.1.1

Bacillolysin
EC 3.4.24.28

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

Chickens for
fattening

—

endo-1,3(4)-beta-
glucanase: 3 000 U

endo-1,4-beta-
glucanase: 9 000 U

alpha-amylase: 540 U

bacillolysin: 450 U

Piglets

Two months

endo-1,3(4)-beta-
glucanase: 2 350 U

endo-1,4-beta-
glucanase: 5 000 U

alpha-amylase: 400 U

bacillolysin: 5 000 U

—

—

—

—

—

—

—

—

Preparation of
endo-1,3(4)-beta-glucanase pro-
duced by Aspergillus aculeatus (CBS
589.94), endo-1,4-beta-glucanase
produced by Trichoderma
longibrachiatum (CBS 592.94),
alpha-amylase produced by Bacillus
amyloliquefaciens (DSM 9553) and
bacillolysin produced by Bacillus
amyloliquefaciens (DSM 9554)
having a minimum activity of:

Endo-1,3(4)-beta-glucanase:
3 000 U (48)/g

Endo-1,4-beta-glucanase:
9 000 U (49)/g
Alpha-amylase: 540 U (51)/g
Bacillolysin: 450 U (52)/g

Preparation of
endo-1,3(4)-beta-glucanase pro-
duced by Aspergillus aculeatus (CBS
589.94), endo-1,4-beta-glucanase
produced by Trichoderma
longibrachiatum (CBS 592.94),
alpha-amylase produced by Bacillus
amyloliquefaciens (DSM 9553) and
bacillolysin produced by Bacillus
amyloliquefaciens (DSM 9554)
having a minimum activity of:

Endo-1,3(4)-beta-glucanase:
2 350 U (48)/g

Endo-1,4-beta-glucanase:
5 000 U (49)/g
Alpha-amylase: 400 U (51)/g
Bacillolysin: 5 000 U (52)/g

End of period of
authorisation

23.11.2004 (o)

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase:
3 000 U

endo-1,4-beta-glucanase: 9 000 U

alpha-amylase: 540 U

bacillolysin: 450 U.

For use in compound feed rich in
starch and non-starch polysaccharides
(mainly cellulose and hemicellulose),
e.g. containing more than 20 %
sunflower meal and 10 % soya meal.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life, and
stability to pelleting.

23.11.2004 (o)

3.

1.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,3(4)-beta-glucanase:
2 350 U

endo-1,4-beta-glucanase: 5 000 U

alpha-amylase: 400 U

bacillolysin: 5 000 U.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans and arabinoxylans), e.g.
containing more than 30 % barley.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
1
2
1

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

Other provisions

No
(or EC No)

59

Endo-1,4-beta-
xylanase
EC 3.2.1.8

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Subtilisin
EC 3.4.21.62

Alpha-amylase
EC 3.2.1.1

Polygalacturo-
nase
EC 3.2.1.15

60

Endo-1,4-beta-xyla-
nase
EC 3.2.1.8

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Chickens for
fattening

—

endo-1,4-beta-
xylanase: 300 U

endo-1,3(4)-beta-
glucanase: 150 U

subtilisin: 4 000 U

alpha-amylase: 400 U

polygalacturonase:
25 U

Chickens for
fattening

—

endo-1,4-beta-
xylanase: 500 U

endo-1,3(4)-beta-gluc-
anase: 5 U

—

—

—

—

—

—

—

Preparation of
endo-1,4-beta-xylanase produced
by Trichoderma longibrachiatum
(ATCC 2105),
endo-1,3(4)-beta-glucanase and
alpha-amylase produced by Bacillus
amyloliquefaciens (DSM 9553),
subtilisin produced by Bacillus
subtilis (ATCC 2107),
polygalacturonase produced by
Aspergillus aculeatus (CBS 589.94)
having a mimimum activity of:

Endo-1,4-beta-xylanase: 300
U (40)/g

Endo-1,3(4)-beta-glucanase:
150 U (22)/g
Subtilisin: 4 000 U (42)/g
Alpha-amylase: 400 U (43)/g
Polygalacturonase: 25 U (44)/g

Preparation of
endo-1,4-beta-xylanase produced
by Trichoderma longibrachiatum
(ATCC 2105),
endo-1,3(4)-beta-glucanase pro-
duced by Trichoderma
longibrachiatum (ATCC 2106)
having a minimum activity of:

Endo-1,4-beta-xylanase:
5 000 U (40)/ml

Endo-1,3(4)-beta-glucanase:
50 U (22)/ml

End of period of
authorisation

28.2.2005 (q)

1.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,4-beta-xylanase: 300 U

endo-1,3(4)-beta-glucanase: 150 U

subtilisin: 4 000 U

alpha-amylase: 400 U

polygalacturonase: 25 U.

For use in compound feed rich in
starch and non-starch polysaccharides
(mainly arabinoxylans and
beta-glucans), e.g. containing more
than 40 % maize.

In the directions for use of the
additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

28.2.2005 (q)

3.

1.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,4-beta-xylanase: 500-2 500 U

endo-1,3(4)-beta-glucanase: 5-25 U.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans and arabinoxylans), e.g.
containing more than 20 % barley
and 40 % wheat.

C

5
0
/
1
2
2

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No
(or EC No)

61

Additive

Chemical formula, description

Species or category
of animal

Maximum age

Endo-1,4-beta-xyla-
nase
EC 3.2.1.8

Endo-1,3(4)-beta-
glucanase
EC 3.2.1.6

Preparation of
endo-1,4-beta-xylanase produced
by Trichoderma reesei (CBS 529.94),
endo-1,3(4)-beta-glucanase pro-
duced by Trichoderma reesei (CBS
526.94) having a minimum
activity of:

Chickens for
fattening

—

Minimum content

Maximum
content

Units of activity/kg of complete feedingstuff

endo-1,4-beta-
xylanase:
17 000 BXU

endo-1,3(4)-beta-gluc-
anase: 11 000 BU

—

—

Powder form:

Endo-1,4-beta-xylanase:
17 000 BXU (34)/g

Endo-1,3(4)-beta-glucanase:
11 000 BU (33)/g

Liquid form:

Endo-1,4-beta-xylanase:
22 000 BXU/ml

Endo-1,3(4)-beta-glucanase:
15 000 BU/ml

Other provisions

End of period of
authorisation

1. 1. In the directions for use of the

28.2.2005 (q)

additive and premixture, indicate the
storage temperature, storage life and
stability to pelleting.

2. Recommended dose per kg of

complete feedingstuff:

endo-1,4-beta-xylanase: 17 000 BXU

endo-1,3(4)-beta-glucanase: 11 000 BU.

3.

For use in compound feed rich in
non-starch polysaccharides (mainly
beta-glucans and arabinoxylans), e.g
containing more than 40 % barley or
55 % wheat.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
1
2
3

No (or EC No)

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

CFU/kg of complete feedingstuff

Other provisions

End of period of
authorisation

C

5
0
/
1
2
4

Micro-organisms

1

Bacillus cereus var. toyoi

NCIMB 40112/CNCM I-1012

Preparation of Bacillus cereus
var. toyoi containing a
minimum of: 1 × 1010 CFU/g
additive

Chickens for fattening

—

0,2 × 109

1 × 109

Laying hens

—

0,2 × 109

1 × 109

Calves

Six months

0,5 × 109

1 × 109

Cattle for fattening

—

0,2 × 109

0,2 × 109

7.10.2004 (h+u)

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

7.10.2004 (h+u)

7.10.2004 (h+u)

7.10.2004 (h+u)

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

May be used in compound
feed containing the permitted
coccidiostats: monensin
sodium, lasolacid sodium,
salinomycin sodium,
decoquinate, robenidine,
narasin, halofuginone.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

The quantity of Bacillus cereus
var. toyoi in the daily ration
must not exceed 1,0 × 109
CFU for 100 kg body weight.
Add 0,2 × 109 CFU for each
additional 100 kg body
weight.

.

.

2
5
2
2
0
0
4

No (or EC No)

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

CFU/kg of complete feedingstuff

Other provisions

End of period of
authorisation

.

.

2
5
2
2
0
0
4

Breeding does

—

0,1 × 109

5 × 109

Rabbits for fattening

—

0,1 × 109

5 × 109

3

Saccharomyces cerevisiae

NCYC Sc 47

Preparation of Saccharomyces
cerevisiae containing a
minimum of: 5 × 109 CFU/g
additive

Rabbits for fattening

—

2,5 × 109

5 × 109

Sows

—

5 × 109

2,5 × 1010

7.10.2004 (h+u)

7.10.2004 (h+u)

30.6.2004 (f)

30.6.2004 (f)

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

May be used in compound
feed containing the permitted
coccidiostat: robenidine.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

May be used in compound
feed containing the permitted
coccidiostats: robenidine,
salinomycin sodium.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life, and
stability to pelleting.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life, and
stability to pelleting.

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
1
2
5

No (or EC No)

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

CFU/kg of complete feedingstuff

Other provisions

End of period of
authorisation

Piglets

Four months

5 × 109

1 × 1010

Dairy cows

—

4 × 108

2 × 109

5

Saccharomyces cerevisiae

CBS 493.94

Preparation of Saccharomyces
cerevisiae containing a
minimum of: 1 × 108 CFU/g
additive

Calves

Six months

2 × 108

2 × 109

Cattle for fattening

—

1,7 × 108

1,7 × 108

30.6.2004 (f)

31.5.2005 (r)

30.6.2004 (f)

30.6.2004 (g)

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life, and
stability to pelleting.

In the directions for use of
the additive and the
premixture, indicate the
storage temperature, storage
life and stability to pelleting.

The quantity of Saccharomyces
cerevisiae in the daily ration
must not exceed 5,6 × 109
CFU per 100 kg of body
weight. Add 8,75 × 109 CFU
per each additional 100 kg
body weight.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life, and
stability to pelleting.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

The quantity of Saccharomyces
cerevisiae in the daily ration
must not exceed 7,5 × 108
CFU for 100 kg body weight.
Add 1 × 108 CFU for each
additional 100 kg body
weight.

C

5
0
/
1
2
6

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No (or EC No)

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

CFU/kg of complete feedingstuff

Other provisions

Dairy cows

—

5 × 107

3,5 × 108

6

Saccharomyces cerevisiae

CNCM I-1079

Preparation of Saccharomyces
cerevisiae containing a
minimum of: 2 × 1010 CFU/g
additive

Sows

—

2 × 109

1 × 1010

Piglets

Four months

6 × 109

3 × 1010

7

Saccharomyces cerevisiae

CNCM I-1077

Preparation of Saccharomyces
cerevisiae containing a
minimum of: 2 × 1010 CFU/g
additive

Dairy cows

—

5,5 × 108

2,1 × 109

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

The quantity of Saccharomyces
cerevisiae in the daily ration
must not exceed 1,2 × 109
CFU for 100 kg body weight.
Add 1,7 × 108 CFU per each
additional 100 kg body
weight.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life, and
stability to pelleting.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life, and
stability to pelleting.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life, and
stability to pelleting.

The quantity of Saccharomyces
cerevisiae in the daily ration
must not exceed 8,4 × 109
CFU for 100 kg body weight.
Add 1,8 × 109 CFU for each
additional 100 kg body
weight.

End of period of
authorisation

31.5.2005 (r)

30.6.2004 (f)

30.6.2004 (f)

30.6.2004 (f)

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
1
2
7

No (or EC No)

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

CFU/kg of complete feedingstuff

Other provisions

Cattle for fattening

—

1 × 109

1,5 × 109

8

Enterococcus faecium

Mixture of:

Chickens for fattening

—

1 × 108

1 × 108

ATCC 53519

Enterococcus faecium

ATCC 55593

[In a 1/1 ratio]

encapsulated Enterococcus
faecium ATCC 53519 and
encapsulated Enterococcus
faecium ATCC 55593
containing a minimum of
2 × 108 CFU/g of the additive
(i.e. a minimum of 1 × 108
CFU/g of each bacterium)

9

Pediococcus acidilactici

CNCM MA 18/5M

Preparation of Pediococcus
acidilactici containing a
minimum of 1 × 1010 CFU/g
of additive

Chickens for fattening

—

1 × 109

1 × 1010

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life, and
stability to pelleting.

The quantity of Saccharomyces
cerevisiae in the daily ration
must not exceed 4,6 × 109
CFU for 100 kg bodyweight.
Add 2 × 109 CFU for each
additional 100 kg
bodyweight.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life, and
stability to pelleting.

May be used in compound
feed containing the permitted
coccidiostats: decoquinate,
halofuginone, lasalocid
sodium, maduramicin
ammonium, monensin
sodium, narasin,
narasin/nicarbazin,
salinomycin sodium.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

May be used in compound
feed containing the permitted
coccidiostats: decoquinate,
halofuginone, narasin,
salinomycin sodium,
maduramicin ammonium,
diclazuril.

C

5
0
/
1
2
8

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

End of period of
authorisation

30.6.2004 (f)

30.6.2004 (f)

30.6.2004 (g)

.

.

2
5
2
2
0
0
4

No (or EC No)

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

CFU/kg of complete feedingstuff

Other provisions

End of period of
authorisation

.

.

2
5
2
2
0
0
4

10

Enterococcus faecium

NCIMB 10415

Preparation of Enterococcus
faecium containing a
minimum of:

Microencapsulated form:
1,0 × 1010 CFU/g additive
1,75 × 1010 CFU/g additive

Piglets

Four months

1 × 109

1 × 109

Pigs for fattening

—

1 × 109

1 × 109

Chickens for fattening

—

0,3 × 109

2,8 × 109

Pigs for fattening

—

0,35 × 109

1,5 × 109

Sows

—

0,2 × 109

1,25 × 109

30.6.2004 (g)

30.6.2004 (g)

30.6.2004 (g)

30.6.2004 (g)

30.6.2004 (g)

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

May be used in compound
feed containing the permitted
coccidiostats: diclazuril,
halofuginone, maduramicin
ammonium, monensin
sodium, robenidine,
salinomycin sodium.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
1
2
9

No (or EC No)

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

CFU/kg of complete feedingstuff

Other provisions

End of period of
authorisation

Cattle for fattening

—

0,25 × 109

0,6 × 109

Piglets

Four months

0,3 × 109

1,4 × 109

Preparation of Enterococcus
faecium containing a
minimum of:

Microencapsulated form:
1,0 × 1010 CFU/g additive
1,75 × 1010 CFU/g additive

and

Granulated form:
3,5 × 1010 CFU/g additive

Calves

Six months

0,35 × 109

6,6 × 109

11

Enterococcus faecium

DSM 5464

Preparation of Enterococcus
faecium containing a
minimum of:
5 × 1010 CFU/g additive

Piglets

Four months

0,5 × 109

1 × 109

30.6.2004 (g)

30.6.2004 (g)

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

The quantity of Enterococcus
faecium in the daily ration
must not exceed 1 × 109 CFU
for 100 kg body weight. Add
1 × 109 CFU for each
additional 100 kg body
weight.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

Granulated form to be used
exclusively in milk replacers.

30.6.2004 (g)

30.6.2004 (g)

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

Granulated form to be used
exclusively in milk replacers.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

C

5
0
/
1
3
0

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No (or EC No)

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

CFU/kg of complete feedingstuff

Other provisions

End of period of
authorisation

Chickens for fattening

—

0,5 × 109

1 × 109

Calves

Four months

0,5 × 109

1 × 109

Piglets

Four months

1 × 109

1 × 1010

Piglets

Four months

1 × 109

1 × 1010

1.4.2004 (l)

1.4.2004 (l)

30.6.2004 (h)

30.6.2004 (h)

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

May be used in compound
feed containing the permitted
coccidiostats: diclazuril,
halofuginone,
monensin-sodium.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

12

Lactobacillus farciminis

CNCM MA 67/4R

13

Enterococcus faecium

DSM 10 663/ NCIMB
10 415

Preparation of Lactobacillus
farciminis containing a
minimum of
1 × 109 CFU/g additive

Preparation of Enterococcus
faecium containing a
minimum of:

Powder and granulated forms:
3,5 × 1010 CFU/g additive

Coated form:
2,0 × 1010 CFU/g additive

Liquid form:
1 × 1010 CFU/ml additive

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
1
3
1

No (or EC No)

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

CFU/kg of complete feedingstuff

Other provisions

End of period of
authorisation

Calves

Six months

1 × 109

1 × 1010

Chickens for fattening

—

1 × 109

1 × 1010

14

Saccharomyces cerevisiae

MUCL 39 885

Preparation of Saccharomyces
cerevisiae containing a
minimum of:

Powder, spheric and oval
granulated forms:
1 × 109 CFU/g additive

Piglets

Four months

3 × 109

3 × 109

26.7.2004 (j)

26.7.2004 (j)

30.6.2004 (h)

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

May be used in compound
feed containing the permitted
coccidiostats: decoquinate,
diclazuril, halofuginone,
lasalocid sodium,
maduramicin ammonium,
monensin sodium, narasin,
nicarbazin, robenidine,
salinomycin sodium.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

C

5
0
/
1
3
2

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No (or EC No)

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

CFU/kg of complete feedingstuff

Other provisions

Cattle for fattening

—

9 × 109

9 × 109

15

Enterococcus faecium

NCIMB 11181

Preparation of Enterococcus
faecium containing a
minimum of:

Powder form:
4 × 1011 CFU/g additive

Coated form:
5 × 1010 CFU/g additive

Calves

Six months

5 × 108

2 × 109

Piglets

Four months

5 × 108

2 × 109

16

Enterococcus faecium

Mixture of:

Calves

Six months

1 × 109

6 × 109

DSM 7134

Lactobacillus rhamnosus

DSM 7133

Enterococcus faecium
containing a minimum of:
7 × 109 CFU/g

and of

Lactobacillus rhamnosus
containing a minimum of:
3 × 109 CFU/g

End of period of
authorisation

30.6.2004 (h)

6.1.2004 (k)

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

The quantity of Saccharomyces
cerevisiae in the daily ration
must not exceed 1,6 × 1010
CFU per 100 kg body weight.
Add 3,2 × 109 CFU for each
additional 100 kg body
weight.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

6.1.2004 (k)

6.1.2004 (k)

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
1
3
3

No (or EC No)

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

CFU/kg of complete feedingstuff

Other provisions

Piglets

Four months

1 × 109

5 × 109

17

Lactobacillus casei

NCIMB 30096

Enterococcus faecium

NCIMB 30098

18

Enterococcus faecium

CECT 4515

Mixture of Lactobacillus casei
and Enterococcus faecium
containing a minimum of:
Lactobacillus casei 2 × 109
CFU/g

and:
Enterococcus faecium 6 × 109
CFU/g

Preparation of Enterococcus
faecium containing a
minimum of 1 × 1010 CFU/g
additive

Calves

Six months

Lactobacillus
casei
0,5 × 109

Enterococcus
faecium
1,5 × 109

Lactobacillus
casei
1 × 109

Enterococcus
faecium
3 × 109

Piglets

Four months

1 × 109

1 × 109

Calves

Six months

1 × 109

1 × 109

19

Streptococcus infantarius

Mixture of:

Calves

Six months

CNCM I-841

Lactobacillus plantarum

CNCM I-840

Streptococcus infantarius and
Lactobacillus plantarum
containing a minimum of:

Streptococcus infantarius
0,5 × 109 CFU/g

and:

Lactobacillus plantarum
2 × 109 CFU/g

Streptococcus
infantarius:
1 × 109

Lactobacillus
plantarum:
0,5 × 109

Streptococcus
infantarius:
1 × 109

Lactobacillus
plantarum:
0,5 × 109

End of period of
authorisation

6.1.2004 (k)

1.4.2004 (l)

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

1.4.2004 (l)

1.4.2004 (l)

17.7.2004 (m)

In the directions for use of
the additive and premixture
indicate the storage
temperature, storage life and
stability to pelleting.

In the directions for use of
the additive and premixture
indicate the storage
temperature, storage life and
stability to pelleting.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life and
stability to pelleting.

C

5
0
/
1
3
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

No (or EC No)

Additive

Chemical formula, description

Species or category of animal

Maximum age

20

Bacillus licheniformis

DSM 5749

Bacillus subtilis

DSM 5750

(In a 1/1 ratio)

Sows

Mixture of Bacillus
licheniformis and Bacillus
subtilis containing a
minimum of:
3,2 × 109 CFU/g of the
additive (1,6 × 109 CFU/g of
each bacterium)

15 days pre
partum and
during lac-
tation period

Minimum
content

Maximum
content

CFU/kg of complete feedingstuff

0,96 × 109

1,92 × 109

Other provisions

End of period of
authorisation

23.11.2004 (o)

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life, and
stability to pelleting.

Pigs for fattening

—

0,48 × 109

1,28 × 109

Chickens for fattening

—

3,2 × 109

3,2 × 109

23.11.2004 (o)

23.11.2004 (o)

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life, and
stability to pelleting.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life, and
stability to pelleting.

May be used in compound
feed containing the permitted
coccidiostats: diclazuril,
halofuginone, monensin
sodium, robenidine and
salinomycin sodium.

.

.

2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
1
3
5

No (or EC No)

Additive

Chemical formula, description

Species or category of animal

Maximum age

Minimum
content

Maximum
content

CFU/kg of complete feedingstuff

Other provisions

End of period of
authorisation

Turkeys for fattening

—

1,28 × 109

3,2 × 109

Calves

Six months

1,28 × 109

1,6 × 109

21

Enterococcus faecium

DSM 3530

Preparation of Enterococcus
faecium containing a
minimum of:
2,5 × 109 CFU/g

Calves

Six months

1 × 109

1 × 109

22

Enterococcus faecium DSM 7134 Preparation of Enterococcus

Piglets

—

0,5 × 109

4 × 109

faecium containing a
minimum of:

Powder:
1 × 1010 CFU/g of additive

Granules (micro-encapsu-
lated):
1 × 1010 CFU/g of additive

Pigs for fattening

—

0,2 × 109

1 × 109

23.11.2004 (o)

28.2.2005 (q)

28.2.2005 (q)

15.4.2007 (ac)

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life, and
stability to pelleting.

May be used in compound
feed containing the permitted
coccidiostats: diclazuril,
halofuginone, monensin
sodium, nifursol and
robenidine.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life, and
stability to pelleting.

In the directions for use of
the additive and premixture,
indicate the storage
temperature, storage life, and
stability to pelleting.

The directions for use must
indicate storage temperature,
shelf life and pelleting
stability of the additive and
the premixture.

15.4.2007 (ac)

The directions for use must
indicate storage temperature,
shelf life and pelleting
stability of the additive and
the premixture.

C

5
0
/
1
3
6

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

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2
5
2
2
0
0
4

(3) 1 FTU is the amount of enzyme which liberates 1 micromole of inorganic phosphate per minute from sodium phytate at pH 5,5 and 37 °C.
(4) 1 IU is the amount of enzyme which liberates 1 micromole of reducing sugar (glucose equivalent) from oat beta-glucan per minute at pH 4,0 and 30 °C.
(5)
1 IU is the amount of enzyme which liberates 1 micromole of reducing sugars (xylose equivalents) from oat xylan per minute at pH 4,0 and 30 °C.
(7)
1 FYT is the amount of enzyme which liberates 1 micromole of inorganic phosphate per minute from sodium phytate at pH 5,5 and 37 °C.
(8)
1 GALU is the amount of enzyme which hydrolyses 1 micromole of p-nitrophenyl-alpha-galactopyranoside per minute at pH 5,5 and 37 °C.
(9) 1 FBG is the amount of enzyme which liberates 1 micromole of reducing sugars (glucose equivalents) from barley beta-glucan per minute at pH 5,0 and 30 °C.
(10) 1 FXU is the amount of enzyme which liberates 7.8 micromoles of reducing sugars (xylose equivalents) from azo-wheat arabinoxylan per minute at pH 6,0 and 50 °C.
(11) 1 FXU is the amount of enzyme which liberates 3.1 micromoles of reducing sugars (xylose equivalents) from azo-wheat arabinoxylan per minute at pH 6,0 and 50 °C.
(12) 1 FXU is the amount of enzyme which liberates 0,15 micromoles of xylose from azurine-cross-linked xylan per minute at pH 5,0 and 40 °C.
(13) 1 BGU is the amount of enzyme which liberates 0,15 micromoles of glucose from azurine-cross-linked beta-glucan per minute at pH 5,0 and 40 °C.
(14) 1 EXU is the amount of enzyme which liberates 1 micromole of reducing sugars (xylose equivalents) from arabinoxylan per minute at pH 3,5 and 55 °C.
(15) 1 RAU is the amount of enzyme which converts 1 mg of soluble starch into a product having an equal absorption to a reference colour at 620 nm after reaction with iodine, per minute at pH 6,6 and 30 °C.
(16) 1 U is the amount of enzyme which liberates 0,1 micromoles of glucose from carboxymethylcellulose per minute at pH 5,0 and 40 °C.
(17) 1 U is the amount of enzyme which liberates 0,1 micromoles of glucose from barley beta-glucan per minute at pH 5,0 and 40 °C.
(18) 1 U is the amount of enzyme which liberates 0,1 micromoles of glucose from oat spelt xylan per minute at pH 5,0 and 40 °C.
(19) 1 BGU is the amount of enzyme which liberates 0,278 micromoles of reducing sugars (glucose equivalents) from barley beta-glucan per minute at pH 3,5 and 40 °C.
(20) 1 EXU is the amount of enzyme which liberates 1 micromole of reducing sugars (xylose equivalents) from wheat arabinoxylan per minute at pH 3,5 and 55 °C.
(21) 1 U is the amount of enzyme which liberates 1 micromole of xylose from birchwood xylan per minute at pH 5,3 and 50 °C.
(22) 1 U is the amount of enzyme which liberates 1 micromole of reducing sugars (glucose equivalents) from barley beta-glucan per minute at pH 5,0 and 30 °C.
(23) 1 CU is the amount of enzyme which liberates 0,128 micromoles of reducing sugars (glucose equivalents) from barley beta-glucan per minute at pH 4,5 and 30 °C.
(24) 1 EPU is the amount of enzyme which liberates 0,0083 micromoles of reducing sugars (xylose equivalents) from oat spelt xylan per minute at pH 4,7 and 30 °C.
(25) 1 U is the amount of enzyme which liberates 5,55 micromoles of reducing sugars (maltose equivalents) from barley beta-glucan per minute at pH 5,0 and 50 °C.
(26) 1 AXC is the amount of enzyme which liberates 17,2 micromoles of reducing sugars (maltose equivalents) from oat xylan per minute at pH 4,7 and 30 °C.
(27) 1 BGN is the amount of enzyme which liberates 1 micromole of reducing sugar (glucose equivalents) from barley beta-glucan per minute at pH 4,8 and 50 °C.
(28) 1 IFP is the amount of enzyme which liberates 1 micromole of reducing sugars (xylose equivalents) from oat xylan per minute at pH 4,8 and 50 °C.
(29) 1 QXU is the amount of enzyme which liberates 1 micromole of reducing sugars (xylose equivalents) from oat xylan per minute at pH 5,1 and 50 °C.
(30) 1 QGU is the amount of enzyme which liberates 1 micromole of reducing sugars (glucose equivalents) from barley beta-glucan per minute at pH 4,8 and 50 °C.
(31) 1 U is the amount of enzyme which liberates 1 micromole of reducing sugars (glucose equivalents) from oat beta-glucan per minute at pH 4,0 and 30 °C.
(32) 1 U is the amount of enzyme which liberates 1 micromole of reducing sugar (glucose equivalent) from oat xylan per minute at pH 4,0 and 30 °C.
(33) 1 BU is the amount of enzyme which liberates 0,06 micromoles of reducing sugars (glucose equivalents) from barley beta-glucan per minute at pH 4,8 and 50 °C.
(34) 1 BXU is the amount of enzyme which liberates 0,06 micromoles of reducing sugars (xylose equivalents) from birch xylan per minute at pH 5,3 and 50 °C.
(35) 1 PPU is the amount of enzyme which liberates 1 micromole of inorganic phosphate from sodium phytate per minute at pH 5 and 37 °C.
(36) 1 U is the amount of enzyme which liberates 2,78 micromoles of reducing sugars (maltose equivalents) from barley beta-glucan per minute at pH 5,0 and 50 °C.
(37) 1 U is the amount of enzyme which liberates 5,55 micromoles of reducing sugars (maltose equivalents) from barley beta-glucan per minute at pH 5,0 and 50 °C.
(38) 1 U is the amount of enzyme which liberates 4,00 micromoles of reducing sugars (maltose equivalents) from birchwood xylan per minute at pH 5,5 and 50 °C.
(39) 1 EU is the amount of enzyme which liberates 1 micromole of reducing sugars (xylose equivalents) from oat xylan per minute at pH 4,5 and 40 °C.
(40) 1 U is the amount of enzyme which liberates 1 micromole of reducing sugars (xylose equivalents) from oat spelt xylan per minute at pH 5,3 and 50 °C.
(41) 1 U is the amount of enzyme which liberates 1 micromole of reducing sugar (glucose equivalent) from wheat starch per minute at pH 4,0 and 30 °C.
(42) 1 U is the amount of enzyme which liberates 1 microgram of phenolic compound (tyrosine equivalents) from a casein substrate per minute at pH 7,5 and 40 °C.
(43) 1 U is the amount of enzyme which hydrolyses 1 micromole of glucosidic linkages from a water insoluble cross-linked starch polymer substrate per minute at pH 6,5 and 37 °C.
(44) 1 U is the amount of enzyme which liberates 1 micromole of reducing material (galacturonic acid equivalents) from a poly D-galacturonic substrate per minute at pH 5,0 and 40 °C.
(45) 1 KNU is the amount of enzyme which liberates 672 micromoles of reducingsugars (glucose equivalent)fromsoluble starch per minute at pH 5,6 and 37 °C.
(46) 1 FYT is the amount of enzyme which liberates 1 micromole of inorganic phosphate per minute from sodium phytate at pH 5,5 and 37 °C.
(47) 1 IU is the amount of enzyme which liberates 1 micromole of reducing sugars (xylose equivalents) from birchwood xylan per minute at pH 4,5 and 30 °C.
(48) 1 U is the amount of enzyme which liberates 0,0056 micromoles of reducing sugars (glucose equivalents) from barley beta-glucan per minute at pH 7,5 and 30 °C.
(49) 1 U is the amount of enzyme which liberates 0,0056 micromoles of reducing sugars (glucose equivalents) from carboxymethylcellulose per minute at pH 4,8 and 50 °C.
(50) 1 U is the amount of enzyme which hydrolyses 1 micromole of glucose from a cross-linked starch polymer per minute at pH 7,5 and 37 °C.
(51) 1 U is the amount of enzyme which hydrolyses 1 micromole of glucosidic linkages from water insoluble cross-linked starch polymer per minute at pH 7,5 and 37 °C.
(52) 1 U is the amount of enzyme which makes 1 microgram of azo-casein soluble in trichloracetic acid per minute at pH 7,5 and 37 °C.
(53) 1 U is the amount of enzyme which liberates 0,0067 micromoles of reducing sugars (xylose equivalents) from birchwood xylan per minute at pH 5,3 and 50 °C.
(c)
(d)
(e)
(f)
(g)
(h)
(h+u) First authorisation Commission Regulation (EC) No 1411/1999 (OJ L 164, 30.6.1999, p. 56), as amended by Commission Regulation (EC) No 256/2002 (OJ L 41, 13.2.2002, p. 6).
(i)
(j)
(k)

First authorisation Commission Regulation (EC) No 2316/98 (OJ L 289, 28.10.1998, p. 4)
First authorisation Commission Regulation(EC) No 639/1999 (OJ L 82, 26.3.1999, p. 6).
First authorisation Commission regulation (EC) No 1245/1999 (OJ L 150, 17.6.1999, p. 15).
First authorisation Commission Regulation (EC) No 1436/98 (OJ L 191, 7.7.1998, p. 15).
First authorisation Commission Regulation (EC) No 866/1999 (OJ L 108, 27.4.1999, p. 21).
First authorisation Commission Regulation (EC) No 1411/99 (OJ L 164, 30.6.1999, p. 56).

First authorisation Commission Regulation (EC) No 2374/98 (OJ L 295, 4.11.1998, p. 3).
First authorisation Commission Regulation (EC) No 1636/1999 (OJ L 194, 27.7.1999, p. 17).
First authorisation Commission Regulation (EC) No 2690/1999 (OJ L 326, 18.12.1999, p. 33).

.

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2
5
2
2
0
0
4

E
N

O

f
f
i
c
i
a
l

J
o
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r
n
a
l

o
f

t
h
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E
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7

(l)
First authorisation Commission Regulation (EC) No 654/2000 (OJ L 79, 30.3.2000, p. 26).
(m)
First authorisation Commission Regulation (EC) No 1353/2000 (OJ L 155, 28.6.2000, p. 15).
(n)
First authorisation Commission Regulation (EC) No 1887/2000 (OJ L 227, 7.9.2000, p. 13).
(o)
First authorisation Commission Regulation (EC) No 2437/2000 (OJ L 280, 4.11.2000, p. 28).
(p)
First authorisation Commission Regulation (EC) No 2697/2000 (OJ L 319, 16.12.2000, p. 1).
(q)
First authorisation Commission Regulation (EC) No 418/2001 (OJ L 62, 2.3.2001, p. 3).
(r)
First authorisation Commission Regulation (EC) No 937/2001 (OJ L 130, 12.5.2001, p. 25).
(s)
First authorisation Commission Regulation (EC) No 1334/2001 (OJ L 180, 3.7.2001, p. 18), as amended by Commission Regulation (EC) No 676/2003 (OJ L 97, 15.04.2003, p. 29).
(t)
First authorisation Commission Regulation (EC) No 2013/2001 (OJ L 272, 13.10.2001, p. 24).
(u)
First authorisation Commission Regulation (EC) No 256/2002 (OJ L 41, 13.2.2002, p. 6).
(v)
First authorisation Commission Regulation (EC) No 1041/2002 (OJ L 157, 15.6.2002, p. 41).
(w)
First authorisation Commission Regulation (EC) No 1252/2002 (OJ L 183, 12.7.2002, p. 10).
(x)
First authorisation Commission Regulation (EC) No 1876/2002 (OJ L 284, 22.10.2002, p. 7).
(y)
First authorisation Commission Regulation (EC) No 2188/2002 (OJ L L 333, 10.12.2002, p. 5).
(aa)
First authorisation Commission Regulation (EC) No 261/2003 (OJ L 37, 13.2.2003, p. 12).
(ab) First authorisation Commission Regulation (EC) No 316/2003 (OJ L 46, 20.2.2002, p. 15).
(ac)
First authorisation Commission Regulation (EC) No 666/2003 (OJ L 96, 12.4.2003, p. 11).
(ad) First authorisation Commission Regulation (EC) No 877/2003 (OJ L 126, 22.5.2003, p. 24).

C

5
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/
1
3
8

E
N

O

f
f
i
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i
a
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J
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4

LIST OF THE AUTHORISED ADDITIVES BELONGING TO THE GROUPS OF ANTIBIOTICS, COCCIDIOSTATS AND GROWTH PROMOTERS IN RE-EVALUATION WITHIN THE SCOPE OF
ARTICLE 9G OF DIRECTIVE 70/524/EEC AND INCLUDED IN ANNEX I BEFORE 1 JANUARY 1988

ANNEX I

.

.

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5
2
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4

Additive
(Trade name)

Composition,
chemical formula,
description

Species or category
of animal

Maximum age

Minimum
content

Maximum
content

mg of active substance/kg of
complete feedingstuff

Other provisions

End of
period of
authorisation

E
N

Name and
registration
number of person
responsible for
putting additive
into circulation

Registration
number of
additive

Antibiotics

E 712

Flavophospholipol

C70H124O40N6P

Laying hens

—

Turkeys

26 weeks

Chickens for
fattening

16 weeks

2

1

1

Piglets

Three months

10

Pigs

Six months

Calves

Six months

Six months

—

1

6

8

2

—

10

40

E 714

Monensin sodium

Cattle for
fattening

Cattle for
fattening

C36H61O11Na
(sodium salt of
a polyether
monocarboxylic
acid produced
by Streptomyces
cinnamonensis)

5

20

20

25

20

16

16

10

—

—

—

Milk replacers only

—

—

Milk replacers only

Indicate in the instructions for use:
‘The quantity of flavophospholipol in the daily
ration must not exceed 40 mg for 100 kg body
weight and 1,5 mg for each additional 10 kg body
weight'.

Indicate in the instructions for use:
‘The quantity of monensin sodium in the daily
ration must not exceed 140 mg for 100 kg body
weight and 6 mg for each additional 10 kg body
weight'.
‘Dangerous for equines'.
‘This feedingstuff contains an ionophore:
simultaneous use with certain medicinal substances
(e.g. tiamulin) can be contra-indicated'.

—

—

—

—

—

—

—

—

—

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
1
3
9

Registration
number of
additive

Name and
registration
number of person
responsible for
putting additive
into circulation

Additive
(Trade name)

Composition,
chemical formula,
description

Species or category
of animal

Maximum age

Minimum
content

Maximum
content

mg of active substance/kg of
complete feedingstuff

Other provisions

End of
period of
authorisation

Chickens for
fattening

—

20

40

Use prohibited at least three days before slaughter

—

Coccidiostats and other medicinal substances

E 756

Decoquinate

E 757

Monensin sodium

3-ethoxycar-
bonyl-4-hy-
droxy-6-decy-
loxy-7-ethoxy-
quinoline

C36H61O11Na
(sodium salt of
a polyether
monocarboxylic
acid produced
by Streptomyces
cinnamonensis)

Chickens for
fattening

—

100

125

Chickens reared
for laying

16 weeks

100

120

Turkeys

16 weeks

90

100

Use prohibited at least three days before slaughter.
Indicate in the instructions for use:
‘Dangerous for equines'.
‘This feedingstuff contains an ionophore:
simultaneous use with certain medicinal substances
(e.g. tiamulin) can be contra-indicated'.

Indicate in the instructions for use:
‘Dangerous for equines'.
‘This feedingstuff contains an ionophore:
simultaneous use with certain medicinal substances
(e.g. tiamulin) can be contra-indicated'.

Use prohibited at least three days before slaughter.
Indicate in the instructions for use:
‘Dangerous for equines'.
‘This feedingstuff contains an ionophore:
simultaneous use with certain medicinal substances
(e.g. tiamulin) can be contra-indicated'.

E 758

Robenidine

1,3-bis[(4-chlor-
obenzylidene)
amino]guani-
dine hydro-
chloride

Chickens for
fattening

Turkeys

Rabbits for
fattening

—

—

—

30

30

50

36

Use prohibited at least five days before slaughter.

36

Use prohibited at least five days before slaughter.

66

Use prohibited at least five days before slaughter.

C

5
0
/
1
4
0

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

—

—

—

—

—

—

Registration
number of
additive

Name and
registration
number of person
responsible for
putting additive
into circulation

Additive
(Trade name)

Composition,
chemical formula,
description

Species or category
of animal

Maximum age

Minimum
content

Maximum
content

mg of active substance/kg of
complete feedingstuff

Other provisions

End of
period of
authorisation

.

.

2
5
2
2
0
0
4

E 763

Lasalocid sodium

E 764

Halofuginone

E 765

Narasin

C34H53O8Na
(sodium salt of
a polyether
monocarboxylic
acid produced
by Streptomyces
lasaliensis)

DL-trans-
7-bromo-
6-chloro-
3-(3-(3-hy-
droxy-2-pi-
peridy)acetonyl)
quinazolin-
4(3H)-one
hydrobromide

C43H72O11
(polyether
monocarboxylic
acid produced
by Streptomyces
aureofaciens)

Chickens for
fattening

—

75

125

Use prohibited at least five days before slaughter.
Indicate in the instructions for use:
‘This feedingstuff contains an ionophore:
simultaneous use with certain medicinal substances
can be contra-indicated'.

—

E
N

Chickens reared
for laying

16 weeks

75

125

Indicate in the instructions for use:
‘This feedingstuff contains an ionophore:
simultaneous use with certain medicinal substances
can be contra-indicated'.

—

Chickens for
fattening

—

Turkeys

12 weeks

2

2

3

Use prohibited at least five days before slaughter.

—

3

Use prohibited at least five days before slaughter.

—

Chickens for
fattening

—

60

70

Use prohibited at least five days before slaughter.
Indicate in the instructions for use:
‘Dangerous for equines'.
‘This feedingstuff contains an ionophore:
simultaneous use with certain medicinal substances
(e.g. tiamulin) can be contra-indicated'.

—

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

C

5
0
/
1
4
1

Name and
registration
number of person
responsible for
putting additive
into circulation

Registration
number of
additive

E 766

Additive
(Trade name)

Composition,
chemical formula,
description

Species or category
of animal

Maximum age

Minimum
content

Maximum
content

mg of active substance/kg of
complete feedingstuff

Other provisions

Chickens for
fattening

—

50

70

Use prohibited at least five days before slaughter.
Indicate in the instructions for use:
‘Dangerous for equines'.
‘This feedingstuff contains an ionophore:
simultaneous use with certain medicinal substances
(e.g. tiamulin) can be contra-indicated'.

Salinomycin
sodium

C42H69O11Na
(sodium salt of
a polyether
monocarboxylic
acid produced
by Streptomyces
albus)
Elaiophylin con-
tent: less than
42 mg per kg
of salinomycin
sodium
17-epi-20-
desoxy-sali-
nomycin con-
tent: less than
40 g per kg of
salinomycin
sodium

End of
period of
authorisation

—

Growth promoters

—

—

—

—

—

—

—

—

—

—

C

5
0
/
1
4
2

E
N

O

f
f
i
c
i
a
l

J
o
u
r
n
a
l

o
f

t
h
e

E
u
r
o
p
e
a
n

U
n
o
n

i

.

.

2
5
2
2
0
0
4

25.2.2004

EN

Official Journal of the European Union

C 50/143

LIST OF THE REFERENCES OF THE COMMUNITY ACTS HAVING MODIFIED THE LIST OF THE
AUTHORISED ADDITIVES SINCE THE 15 NOVEMBER 2001 (1)

ANNEX II

Reg. 2380/2001

Commission Regulation (EC) No 2380/2001 of 5 December
2001 concerning the 10 year authorisation of an additive in
feedingstuffs

OJ L 321, 6.12.2001, p. 18

Reg. 256/2002

Commission Regulation (EC) No 256/2002 of 12 February
2002 concerning the provisional authorisation of new
additives, the prolongation of provisional authorisation of an
additive and the permanent authorisation of an additive in
feedingstuffs

OJ L 41, 13.2.2002, p. 6

Reg. 1041/2002

Commission Regulation (EC) No 1041/2002 of 14 June 2002
concerning the provisional authorisation of a new additive in
feedingstuffs

OJ L 157, 15.6.2002, p. 41

Reg. 1252/2002

Commission Regulation (EC) No 1252/2002 of 11 July 2002
concerning the provisional authorisation of a new additive in
feedingstuffs

OJ L 183, 12.7.2002, p. 10

Reg. 1756/2002

Council Regulation (EC) No 1756/2002 of 23 September
2002 amending Directive 70/524/EEC concerning additives in
feedingstuffs as regards withdrawal of the authorisation of an
additive and amending Commission Regulation (EC) No
2430/1999

OJ L 265, 3.10.2002, p. 1

Reg. 1876/2002

Commission Regulation (EC) No 1876/2002 of 21 October
2002 concerning the provisional authorisation of a new use
of an additive in feedingstuffs

OJ L 284, 22.10.2002, p. 7

Reg. 2188/2002

Commission Regulation (EC) No 2188/2002 of 9 December
2002 concerning the provisional authorisation of new uses of
additives in feedingstuffs

OJ L 333, 10.12.2002, p. 5

Dir. 2003/7/EC

Commission Directive 2003/7/EC of 24 January 2003
amending the conditions for authorisation of canthaxanthin
in accordance with Council Directive
in feedingstuffs
70/524/EEC

OJ L 22, 25.1.2003, p. 28

Reg. 162/2003

Commission Regulation (EC) No 162/2003 of 30 January
in
2003 concerning the
feedingstuffs

authorisation of

an additive

OJ L 26, 31.1.2003, p. 3

Reg. 261/2003

Commission Regulation (EC) No 261/2003 of 12 February
2003 concerning the provisional authorisation of new uses of
additives in feedingstuffs

OJ L 37, 13.2.2003, p. 12

Reg. 316/2003

Reg. 355/2003

Commission Regulation (EC) No 316/2003 of 19 February
2003 concerning the permanent authorisation of an additive
in feedingstuffs and the provisional authorisation of a new
use of an additive already authorised in feedingstuffs

OJ L 46, 20.2.2002, p. 15

Council Regulation (EC) No 355/2003 of 20 February 2003
avilamycin in
on the
feedingstuffs

authorisation of

additive

the

OJ L 53, 28.2.2003, p. 1

(1) List of the authorised additives in feedingstuffs published in application of Article 9t (b) of Council Directive 70/524/EEC concerning

additives in feedingstuffs (OJ C 329, 31.12.2002, p. 1)

C 50/144

EN

Official Journal of the European Union

25.2.2004

Reg. 666/2003

Commission Regulation (EC) No 666/2003 of 11 April 2003
provisionally authorising the use of certain micro-organisms
in feedingstuffs

OJ L 96, 12.4.2003, p. 11

Reg. 668/2003

Commission Regulation (EC) No 668/2003 of 11 April 2003
concerning the permanent authorisation of an additive in
feedingstuffs

OJ L 96, 12.4.2003, p. 14

Reg. 676/2003

Reg. 871/2003

Reg. 877/2003

Commission Regulation (EC) No 676/2003 of 14 April 2003
amending Regulation (EC) No 1334/2001 concerning the
provisional authorisation of a new additive in feedingstuffs

OJ L 97, 15.4.2003, p. 29

Commission Regulation (EC) No 871/2003 of 20 May 2003
permanently authorising a new additive manganomanganic
oxide in feedingstuffs

OJ L 125, 21.5.2003, p. 3

Commission Regulation (EC) No 877/2003 of 21 May 2003
provisionally authorising the use of
the acidity regulator
‘Benzoic acid' in feedingstuffs'

OJ L 126, 22.5.2003, p. 24

Dir. 2003/57/EC

Commission Directive 2003/57/EC of 17 June 2003
amending Directive 2002/32/EC of the European Parliament
and of the Council on undesirable substances in animal feed

OJ L 151, 19.6.2003, p. 38