Lisa Grimaldi is a fictional character from the CBS soap opera, As the World Turns. The character was portrayed by Eileen Fulton for 50 years from May 1960, until the last episode aired in September 2010, with Fulton becoming one of the longest-serving soap opera actors in the United States. Lisa is considered to be the first soap "vixen" and was one half of the first ever super couple, Bob and Lisa Hughes.