Lesley Webber is a fictional character from General Hospital, an American soap opera on the ABC network. Denise Alexander originated the role from 1973 through February 28, 1984, as a series regular and from 1996 to 2009 in a recurring status. Alexander returned to the series briefly in 2013, to celebrate its 50th anniversary, and has made subsequent appearances in 2017, 2019 and 2021.