Blair Cramer (raised as Blair Daimler; formerly Buchanan, Manning, Holden, McBain, and Clarke) is a fictional character from the American daytime drama series One Life to Live. The niece of leading antagonist Dr. Dorian Cramer Lord of the Cramer family, the role was originally played by actress Mia Korf from 1991 through 1993. Blair has since become most associated with actress Kassie DePaiva, who played the role for nearly 20 years on ABC Daytime, from December 17, 1993 until the original OLTL finale episode January 13, 2012, and in several guest appearances on the last original ABC daytime serial General Hospital from March 2, 2012 through December 3, 2012. DePaiva reprised the role when new regular episodes of OLTL debuted on Hulu, iTunes, and FX Canada via The Online Network April 29, 2013.