 "4 Minutes" was released as the lead single from the album on March 17, 2008 by Warner Bros. Records. "4 Minutes" has been praised by many contemporary critics. Some have noted, however, that it was Madonna rather than Timberlake who appeared to be the featured artist on the track. "4 Minutes" achieved international success by topping the charts in 21 countries worldwide. It became Madonna's 13th number-one single in the United Kingdom, the highest total for any female artist in the British charts. In the United States, "4 Minutes" peaked at number three on the Billboard Hot 100, giving Madonna her 37th Top Ten hit, breaking the record previously held by Elvis Presley. In the song's accompanying music video, Madonna and Timberlake sing and run away from a giant black screen that devours everything in its path. At the end of the video, Madonna and Timberlake are consumed by the screen. The song received a Grammy nomination in the Best Pop Collaboration with Vocals category.
