 The episode utilised props and costumes from previous Star Trek series in order to represent the Borg and is where they make their last canon appearance. The guest cast including Bonita Friedericy, the wife of main cast member John Billingsley. The ratings received by the episode were similar to those received during the previous week, and the number of viewers were one of the highest for the year. The critical response to "Regeneration" was mixed, with concerns directed at potential continuity problems, and that the appearance of the Borg was a little obvious. A follow-up episode to "Regeneration" featuring the return of Alice Krige as the Borg Queen was pitched for the fifth season of Star Trek: Enterprise but the show was cancelled before the fifth season could be released and thus the episode never aired.
