 Drosera regia is often described as being a difficult species to cultivate, though modern reports on its cultivation have indicated which conditions have led to success for some. For optimal growth, D. regia appears to require good soil drainage and sufficient light levels, and prefers cooler temperatures. Cool nights and warm days have been reported to induce vigorous growth. Asexual propagation is frequently achieved through small root cuttings instead of leaf cuttings, which tend to rot before roots can form. Seed germination occurs as early as 10 days to 3 or 4 weeks with fresh seed, faster than many other Drosera species. Germination is phanerocotylar (non-glandular cotyledons exposed, free from seed coverings), with the first true leaves being alternate in arrangement.
