 Once it enters the San Joaquin Valley, SR 46, known as the Paso Robles Highway, follows an almost perfectly straight eastward alignment, crossing SR 33 at Blackwells Corner, passing through the Lost Hills Oil Field, and intersecting I-5 about two miles (3 km) past Lost Hills and the crossing of the California Aqueduct. SR 46 then passes through the Semitropic Oil Field about seven miles west of Wasco. SR 46 and SR 43 overlap for a short distance in the city of Wasco, and then SR 46 passes over Calloway Canal and Friant Canal before it ends at SR 99 in Famoso. The county-maintained Famoso Road continues east across SR 65 and into the Sierra Nevada foothills.
