 As far as known, Oryzomys gorgasi has a disjunct distribution in northwestern South America, including Colombia, Venezuela, and Curaçao. In a 2009 paper, Carleton and Arroyo-Cabrales speculated that its distribution may extend into Central America. The Colombian population is known from the holotype only, caught at Loma Teguerre (7°54'N, 77°W) in Antioquia Department, northwestern Colombia, near the Río Atrato, at about 1 m above sea level. The location is apparently a freshwater swamp, and Hershkovitz suggested that O. gorgasi probably occurred throughout the swamp forests in the Río Atrato basin. On Curaçao, it is known from cave faunas at Tafelberg Santa Barbara, Noordkant, Ser'i Kura, and Hermanus. At Tafelberg Santa Barbara, it was found in association with introduced black rats (Rattus rattus), indicating that the population persisted at least until the first European contact in 1499.
