 The first volcanic activity of Tuzgle occurred 650,000 years ago and formed the Tuzgle Ignimbrite. Subsequently, lava domes were erupted and three lava flow units were named San Antonio, Azufre, and Tuzgle. The latest lava flows are dated at 17.5 and 1.5 Ma and volcanic activity may have continued into the Holocene. Several thermal springs are associated with the volcano, and some have been investigated for possible geothermal energy production. Sulfur was formerly mined on the mountain. Argentina's National Route 40 runs along the foot of the volcano.
