 In 1947 Hollywood, "toons" act out theatrical cartoon shorts as with live-action films; they regularly interact with real people and animals and reside in Toontown, an animated portion of Los Angeles. Private detective Eddie Valiant and his brother, Teddy, once worked closely with the toons on several famous cases, but after Teddy was killed by a toon, Eddie lapsed into alcoholism and vowed never to work for toons again. One day, R.K. Maroon, head of Maroon Cartoon Studios, is concerned about the recent poor acting performances of one of his biggest stars, Roger Rabbit. Maroon hires Valiant to investigate rumors about Roger's voluptuous toon wife Jessica being romantically involved with businessman and gadgets inventor, Marvin Acme, owner of both Acme Corporation and Toontown. After watching Jessica perform at the underground Ink & Paint Club, Valiant secretly takes photographs of her and Acme playing patty-cake in her dressing room, which he shows to Roger. Maroon suggests to Roger that he should leave Jessica, but a drunken Roger refuses and flees.
