 Pricetown Road dates back to the 18th century as a road linking the village of Pricetown to Reading. The road was used by farmers in the Pricetown area who traveled to Reading to buy and sell wares. Pricetown was settled in 1754 and grew into a village with three taverns and a general store that served the trade to and from Reading. In the 19th century, Pricetown Road was used to transport Montana horses from Temple to country auctions in the area. Pricetown Road was originally an unpaved road. Warren Street in Reading was constructed by 1920, running from Fayette Street near the Tulpehocken Creek east to a dead end near the Schuylkill River. In 1927, Pricetown Road was paved in concrete. The road was straightened at the Walnuttown Road intersection by 1940.
