 GameSpot gave the game an 8 out of 10, praising the game's characters, art, voice acting and challenging gameplay. However, they noted that at times that spoken dialogue sometimes did not match the displayed text dialogue. A reviewer of PC Gamer scored the game 69 out of 100, noting that Space Run attempts to reverse the typical tower defense concept, but ultimately relies on memorizing missions rather than clever design. The reviewer considered the best part of the game to be the time bonus, which is necessary to earn full reputation.
