 Inseminoid attracted positive critical reception on its original release. In terms of box office performance, it reached a high of fifth position in the 1981 British charts. At one point it ranked seventh at the box office in France, while in the United States it proceeded to enter the Los Angeles Times list of top ten films. American director Roger Corman congratulated Warren on the film and considered commissioning him for further productions. However, a private screening had failed to impress members of the British Academy of Film and Television Arts, who dismissed Inseminoid as "'Commercial rubbish! ... Not the sort of thing the Academy should be showing ... And certainly not the kind of film the British film industry should be making!'"
