dkoterwa/mlqa_filtered huggingface dataset:
Mutations alter an organism's genotype and occasionally this causes different phenotypes to appear. Most mutations have little effect on an organism's phenotype, health, or reproductive fitness. Mutations that do have an effect are usually detrimental, but occasionally some can be beneficial. Studies in the fly Drosophila melanogaster suggest that if a mutation changes a protein produced by a gene, about 70 percent of these mutations will be harmful with the remainder being either neutral or weakly beneficial.

Question: Which fly was studied?
Answer: Drosophila melanogaster

Question: What appears differently sometimes when mutations occur?
Answer: phenotypes
Population genetics studies the distribution of genetic differences within populations and how these distributions change over time. Changes in the frequency of an allele in a population are mainly influenced by natural selection, where a given allele provides a selective or reproductive advantage to the organism, as well as other factors such as mutation, genetic drift, genetic hitchhiking, artificial selection and migration.Over many generations, the genomes of organisms can change significantly, resulting in evolution. In the process called adaptation, selection for beneficial mutations can cause a species to evolve into forms better able to survive in their environment. New species are formed through the process of speciation, often caused by geographical separations that prevent populations from exchanging genes with each other.By comparing the homology between different species' genomes, it is possible to calculate the evolutionary distance between them and when they may have diverged. Genetic comparisons are generally considered a more accurate method of characterizing the relatedness between species than the comparison of phenotypic characteristics. The evolutionary distances between species can be used to form evolutionary trees; these trees represent the common descent and divergence of species over time, although they do not show the transfer of genetic material between unrelated species (known as horizontal gene transfer and most common in bacteria).

Question: What is it called when mutations can cause a species to evolve into better forms and have a higher survival rate in their habitat?
Answer: adaptation
The genome of a given organism contains thousands of genes, but not all these genes need to be active at any given moment. A gene is expressed when it is being transcribed into mRNA and there exist many cellular methods of controlling the expression of genes such that proteins are produced only when needed by the cell. Transcription factors are regulatory proteins that bind to DNA, either promoting or inhibiting the transcription of a gene. Within the genome of Escherichia coli bacteria, for example, there exists a series of genes necessary for the synthesis of the amino acid tryptophan. However, when tryptophan is already available to the cell, these genes for tryptophan synthesis are no longer needed. The presence of tryptophan directly affects the activity of the genes—tryptophan molecules bind to the tryptophan repressor (a transcription factor), changing the repressor's structure such that the repressor binds to the genes. The tryptophan repressor blocks the transcription and expression of the genes, thereby creating negative feedback regulation of the tryptophan synthesis process.

Question: How many genes are contained within a genome?
Answer: thousands
The use of ligation enzymes allows DNA fragments to be connected. By binding ("ligating") fragments of DNA together from different sources, researchers can create recombinant DNA, the DNA often associated with genetically modified organisms. Recombinant DNA is commonly used in the context of plasmids: short circular DNA molecules  with a few genes on them. In the process known as molecular cloning, researchers can amplify the DNA fragments by inserting plasmids into bacteria and then culturing them on plates of agar (to isolate clones of bacteria cells—"cloning" can also refer to the various means of creating cloned ("clonal") organisms).

Question: What process is allows for the DNA to amplify fragments?
Answer: Recombinant DNA
Within eukaryotes, there exist structural features of chromatin that influence the transcription of genes, often in the form of modifications to DNA and chromatin that are stably inherited by daughter cells. These features are called "epigenetic" because they exist "on top" of the DNA sequence and retain inheritance from one cell generation to the next. Because of epigenetic features, different cell types grown within the same medium can retain very different properties. Although epigenetic features are generally dynamic over the course of development, some, like the phenomenon of paramutation, have multigenerational inheritance and exist as rare exceptions to the general rule of DNA as the basis for inheritance.

Question: What features do the cell types have?
Answer: epigenetic
After receiving his Juris Doctor in 1973 from the University of Virginia School of Law, Mueller worked as a litigator at the firm Pillsbury, Madison and Sutro in San Francisco until 1976. He then served for 12 years in United States Attorney offices. He first worked in the office of the U.S. Attorney for the Northern District of California in San Francisco, where he rose to be chief of the criminal division, and in 1982, he moved to Boston to work in the office of the U.S. Attorney for Massachusetts as an Assistant United States Attorney, where he investigated and prosecuted major financial fraud, terrorism and public corruption cases, as well as narcotics conspiracies and international money launderers.After serving as a partner at the Boston law firm of Hill and Barlow, Mueller returned to government service. In 1989, he served in the United States Department of Justice as an assistant to Attorney General Dick Thornburgh and as acting Deputy Attorney General. James Baker, with whom he worked on national security matters, said he had "an appreciation for the Constitution and the rule of law".In 1990, he became the United States Assistant Attorney General in charge of the United States Department of Justice Criminal Division. During his tenure, he oversaw prosecutions including that of Panamanian leader Manuel Noriega, the Pan Am Flight 103 (Lockerbie bombing) case, and of the Gambino crime family boss John Gotti.In 1991, he declared the government had been investigating the Bank of Credit and Commerce International (BCCI) since 1986 in more-than-usual media exposure. Also in 1991, he was elected a fellow of the American College of Trial Lawyers.In 1993, Mueller became a partner at Boston's Hale and Dorr, specializing in white-collar crime litigation. He returned to public service in 1995 as senior litigator in the homicide section of the District of Columbia United States Attorney's Office. In 1998, Mueller was named U.S. Attorney for the Northern District of California and held that position until 2001.

Question: Where did Mueller earn his Juris Doctor?
Answer: University of Virginia School of Law
Visual impairment, also known as vision impairment or vision loss, is a decreased ability to see to a degree that causes problems not fixable by usual means, such as glasses. Some also include those who have a decreased ability to see because they do not have access to glasses or contact lenses. Visual impairment is often defined as a best corrected visual acuity of worse than either 20/40 or 20/60. The term blindness is used for complete or nearly complete vision loss. Visual impairment may cause people difficulties with normal daily activities such as driving, reading, socializing, and walking.The most common causes of visual impairment globally are uncorrected refractive errors (43%), cataracts (33%), and glaucoma (2%). Refractive errors include near sighted, far sighted, presbyopia, and astigmatism. Cataracts are the most common cause of blindness. Other disorders that may cause visual problems include age related macular degeneration, diabetic retinopathy, corneal clouding, childhood blindness, and a number of infections. Visual impairment can also be caused by problems in the brain due to stroke, premature birth, or trauma among others. These cases are known as cortical visual impairment. Screening for vision problems in children may improve future vision and educational achievement. Screening adults without symptoms is of uncertain benefit. Diagnosis is by an eye exam.The World Health Organization (WHO) estimates that 80% of visual impairment is either preventable or curable with treatment. This includes cataracts, the infections river blindness and trachoma, glaucoma, diabetic retinopathy, uncorrected refractive errors, and some cases of childhood blindness. Many people with significant visual impairment benefit from vision rehabilitation, changes in their environment, and assistive devices.As of 2015 there were 940 million people with some degree of vision loss. 246 million had low vision and 39 million were blind. The majority of people with poor vision are in the developing world and are over the age of 50 years. Rates of visual impairment have decreased since the 1990s. Visual impairments have considerable economic costs both directly due to the cost of treatment and indirectly due to decreased ability to work.

Question: Among common eye problems, what condition is the most common cause of blindness?
Answer: Cataracts
2 H2(g) + O2(g) → 2 H2O(l) + 572 kJ (286 kJ/mol)Hydrogen gas forms explosive mixtures with air in concentrations from 4–74% and with chlorine at 5–95%. The explosive reactions may be triggered by spark, heat, or sunlight. The hydrogen autoignition temperature, the temperature of spontaneous ignition in air, is 500 °C (932 °F). Pure hydrogen-oxygen flames emit ultraviolet light and with high oxygen mix are nearly invisible to the naked eye, as illustrated by the faint plume of the Space Shuttle Main Engine, compared to the highly visible plume of a Space Shuttle Solid Rocket Booster, which uses an ammonium perchlorate composite. The detection of a burning hydrogen leak may require a flame detector; such leaks can be very dangerous. Hydrogen flames in other conditions are blue, resembling blue natural gas flames.The destruction of the Hindenburg airship was a notorious example of hydrogen combustion and the cause is still debated. The visible orange flames in that incident were the result of a rich mixture of hydrogen to oxygen combined with carbon compounds from the airship skin.

Question: What is the temperature that could be triggered by a spark
Answer: 500 °C (932 °F)

Question: when will hydrogen gas become explosive?
Answer: with air in concentrations from 4–74% and with chlorine at 5–95%
2H, the other stable hydrogen isotope, is known as deuterium and contains one proton and one neutron in the nucleus. All deuterium in the universe is thought to have been produced at the time of the Big Bang, and has endured since that time. Deuterium is not radioactive, and does not represent a significant toxicity hazard. Water enriched in molecules that include deuterium instead of normal hydrogen is called heavy water. Deuterium and its compounds are used as a non-radioactive label in chemical experiments and in solvents for 1H-NMR spectroscopy. Heavy water is used as a neutron moderator and coolant for nuclear reactors. Deuterium is also a potential fuel for commercial nuclear fusion.

Question: What is the name of the other stable hydrogen isotope?
Answer: 2H
Baekje was founded by Onjo, the third son of Goguryeo's founder Jumong and So Seo-no, at Wiryeseong (present-day southern Seoul). Baekje, like Goguryeo, claimed to succeed Buyeo, a state established in present-day Manchuria around the time of Gojoseon's fall.

Question: What was the original name of the city located where Seoul is today?
Answer: Wiryeseong
After parliamentary elections, the parties negotiate among themselves on forming a new cabinet (the Finnish Government), which then has to be approved by a simple majority vote in the parliament. The cabinet can be dismissed by a parliamentary vote of no confidence, although this rarely happens (the last time in 1957), as the parties represented in the cabinet usually make up a majority in the parliament.The cabinet exercises most executive powers, and originates most of the bills that the parliament then debates and votes on. It is headed by the Prime Minister of Finland, and consists of him or her, of other ministers, and of the Chancellor of Justice. The current prime minister is Juha Sipilä (Centre Party). Each minister heads his or her ministry, or, in some cases, has responsibility for a subset of a ministry's policy. After the prime minister, the most powerful minister is the minister of finance. The incumbent Minister of Finance is Petteri Orpo.

Question: Who else makes up the Finnish Government besides any ministers?
Answer: the Chancellor of Justice
Finland is highly integrated into the global economy, and international trade produces one third of GDP. Trade with the European Union makes up 60% of Finland's total trade. The largest trade flows are with Germany, Russia, Sweden, the United Kingdom, the United States, the Netherlands, and China. Trade policy is managed by the European Union, where Finland has traditionally been among the free trade supporters, except for agricultural policy. Finland is the only Nordic country to have joined the Eurozone.

Question: Which European countries to spend and trade with the most?
Answer: Germany, Russia, Sweden, the United Kingdom, the United States, the Netherlands
Finnish and Swedish are the official languages of Finland. Finnish predominates nationwide while Swedish is spoken in some coastal areas in the west and south and in the autonomous region of Åland. The native language of 89% of the population is Finnish, which is part of the Finnic subgroup of the Uralic languages. The language is one of only four official EU languages not of Indo-European origin. Finnish is closely related to Karelian and Estonian and more remotely to the Sami languages and Hungarian. Swedish is the native language of 5.3% of the population (Swedish-speaking Finns).The Nordic languages and Karelian are also specially treated in some contexts.

Question: What language do the majority of the people in Finland speak?
Answer: Finnish
Various sporting events are popular in Finland. Pesäpallo, resembling baseball, is the national sport of Finland, although the most popular sports in terms of spectators is ice hockey. Ice Hockey World Championships 2016 final Finland-Canada, 69% of Finnish people watched that game on TV. Other popular sports include athletics, cross-country skiing, ski jumping, football, volleyball and basketball. While ice hockey is the most popular sports when it comes to attendance at games, association football is the most played team sport in terms of the number of players in the country and is also the most appreciated sport in Finland.In terms of medals and gold medals won per capita, Finland is the best performing country in Olympic history. Finland first participated as a nation in its own right at the Olympic Games in 1908, while still an autonomous Grand Duchy within the Russian Empire. At the 1912 Summer Olympics, great pride was taken in the three gold medals won by the original "Flying Finn" Hannes Kolehmainen.

Question: How did the Olympic games classify Finland until 1908?
Answer: an autonomous Grand Duchy within the Russian Empire
Although no attendance records for the period survive, most biographers agree that Shakespeare was probably educated at the King's New School in Stratford, a free school chartered in 1553, about a quarter-mile (400 m) from his home. Grammar schools varied in quality during the Elizabethan era, but grammar school curricula were largely similar: the basic Latin text was standardised by royal decree, and the school would have provided an intensive education in grammar based upon Latin classical authors.At the age of 18, Shakespeare married 26-year-old Anne Hathaway. The consistory court of the Diocese of Worcester issued a marriage licence on 27 November 1582. The next day, two of Hathaway's neighbours posted bonds guaranteeing that no lawful claims impeded the marriage. The ceremony may have been arranged in some haste since the Worcester chancellor allowed the marriage banns to be read once instead of the usual three times, and six months after the marriage Anne gave birth to a daughter, Susanna, baptised 26 May 1583. Twins, son Hamnet and daughter Judith, followed almost two years later and were baptised 2 February 1585. Hamnet died of unknown causes at the age of 11 and was buried 11 August 1596.

Question: what are the twins names?
Answer: son Hamnet and daughter Judith
Shakespeare was not revered in his lifetime, but he received a large amount of praise. In 1598, the cleric and author Francis Meres singled him out from a group of English writers as "the most excellent" in both comedy and tragedy. The authors of the Parnassus plays at St John's College, Cambridge, numbered him with Chaucer, Gower, and Spenser. In the First Folio, Ben Jonson called Shakespeare the "Soul of the age, the applause, delight, the wonder of our stage", although he had remarked elsewhere that "Shakespeare wanted art".Between the Restoration of the monarchy in 1660 and the end of the 17th century, classical ideas were in vogue. As a result, critics of the time mostly rated Shakespeare below John Fletcher and Ben Jonson. Thomas Rymer, for example, condemned Shakespeare for mixing the comic with the tragic. Nevertheless, poet and critic John Dryden rated Shakespeare highly, saying of Jonson, "I admire him, but I love Shakespeare". For several decades, Rymer's view held sway; but during the 18th century, critics began to respond to Shakespeare on his own terms and acclaim what they termed his natural genius. A series of scholarly editions of his work, notably those of Samuel Johnson in 1765 and Edmond Malone in 1790, added to his growing reputation. By 1800, he was firmly enshrined as the national poet. In the 18th and 19th centuries, his reputation also spread abroad. Among those who championed him were the writers Voltaire, Goethe, Stendhal, and Victor Hugo.

Question: Although he received a lot of praise during his lifetime Shakespeare was not what?
Answer: revered
William Shakespeare (bapt. 26 April 1564 – 23 April 1616) was an English poet, playwright and actor, widely regarded as the greatest writer in the English language and the world's greatest dramatist. He is often called England's national poet and the "Bard of Avon". His extant works, including collaborations, consist of approximately 39 plays, 154 sonnets, two long narrative poems, and a few other verses, some of uncertain authorship. His plays have been translated into every major living language and are performed more often than those of any other playwright.Shakespeare was born and raised in Stratford-upon-Avon, Warwickshire. At the age of 18, he married Anne Hathaway, with whom he had three children: Susanna and twins Hamnet and Judith. Sometime between 1585 and 1592, he began a successful career in London as an actor, writer, and part-owner of a playing company called the Lord Chamberlain's Men, later known as the King's Men. At age 49 (around 1613), he appears to have retired to Stratford, where he died three years later. Few records of Shakespeare's private life survive; this has stimulated considerable speculation about such matters as his physical appearance, his sexuality, his religious beliefs, and whether the works attributed to him were written by others. Such theories are often criticised for failing to adequately note that few records survive of most commoners of the period.

Question: How many plays did Shakespeare write?
Answer: 39
William Shakespeare was the son of John Shakespeare, an alderman and a successful glover (glove-maker) originally from Snitterfield, and Mary Arden, the daughter of an affluent landowning farmer. He was born in Stratford-upon-Avon and baptised there on 26 April 1564. His actual date of birth remains unknown, but is traditionally observed on 23 April, Saint George's Day. This date, which can be traced to a mistake made by an 18th-century scholar, has proved appealing to biographers because Shakespeare died on the same date in 1616. He was the third of eight children, and the eldest surviving son.

Question: Who was William Shakespeare's father?
Answer: John Shakespeare
In 1945, Logan is held in a Japanese POW camp near Nagasaki. During the atomic bombing of Nagasaki, Logan saves an officer named Ichirō Yashida by shielding him from the blast.

Question: What year was Logan a POW?
Answer: 1945
In a mid-credits scene, Logan returns to the United States two years later and is approached at the airport by Erik Lehnsherr, who warns him of a grave new threat to the mutant race; and Charles Xavier, whom Logan previously thought was dead.

Question: where does logan return to?
Answer: United States
In the present day, Logan lives as a hermit in Yukon, tormented by hallucinations of Jean Grey, whom he was forced to kill to save the world. He is located by Yukio, a mutant with the ability to foresee people's deaths, on behalf of Ichirō, now the CEO of a technology zaibatsu. Ichirō, who is dying of cancer, wants Logan to accompany Yukio to Japan so that he may repay his life debt. In Tokyo, Logan meets Ichirō's son, Shingen, and granddaughter, Mariko. There, Ichirō offers to transfer Logan's healing abilities into his own body, thus saving Ichirō's life and alleviating Logan of his near-immortality, which Logan views as a curse. Logan refuses and prepares to leave the following day. That night, Ichirō's physician Dr. Green introduces something into Logan's body, but Logan dismisses it as a dream.

Question: Where does Logan live?
Answer: Yukon
Mariko is brought before Shingen at Ichirō's estate where he attempts to kill her. The Blackfoot Ninjas led by Harada and accompanied by Dr. Green arrive and attack the compound. Dr. Green stabs Shingen in the neck with a poisoned pen and the Ninjas whisk Mariko away. Logan and Yukio arrive later and, using Ichirō's X-ray machine, discover a robotic parasite attached to Logan's heart, suppressing his healing ability. Logan cuts himself open and extracts the device. During the operation, Shingen, who survived Dr. Green's attack, attempts to kill Logan but Yukio holds Shingen off long enough for Logan to recover and kill Shingen. Logan follows Mariko's trail to the village of Ichirō's birth, where he is captured by Harada's ninjas. Logan is placed in a machine by Dr. Green, who reveals her plans to extract his healing factor and introduces him to the Silver Samurai, an electromechanical suit of Japanese armor with energized swords made of adamantium. Harada tries to convince Mariko that the events happening are for her well being but Mariko escapes from Harada by stabbing him in the leg. Harada sees the error of his ways and while attempting to stop the Silver Samurai he is killed.

Question: What was the impact the parasite had on Logan's heart?
Answer: suppressing his healing ability

Question: Where is Logan places?
Answer: in a machine

Question: Who ends up dead in the end?
Answer: Shingen
Meanwhile, Yukio arrives and kills Dr. Green. As Logan fights the Silver Samurai. The Silver Samurai severs Logan's adamantium claws and begins to extract Logan's healing abilities through his bone marrow, revealing himself to be Ichirō, who had faked his death. Ichirō regains his youth, but Mariko intervenes and stabs Ichirō with Logan's severed claws. Logan regenerates his bone claws and kills Ichirō. Logan collapses and has one final hallucination of Jean, in which he decides to finally let her go. Mariko becomes CEO of Yashida Industries and bids farewell to Logan as he prepares to leave Japan. Yukio vows to stay by Logan's side as his bodyguard, and they depart to places unknown.

Question: What company does Mariko work for?
Answer: Yashida Industries