NFL 2025 season, Week 1 (REG): SF at SEA
Date: Sunday, 2025-09-07 at 16:05
Stadium: Lumen Field (roof: outdoors, surface: fieldturf)
Weather: 67 F, wind 6 mph
Final score: SF 17, SEA 13
Starting quarterbacks: Brock Purdy (SF) vs Sam Darnold (SEA)
Head coaches: Kyle Shanahan (SF) vs Mike Macdonald (SEA)
Referee: Shawn Hochuli
Betting lines: spread -2.5, over/under 43.5, moneylines SF -135 / SEA 114
Rest days: SF 7, SEA 7