{
 "id": "125ce4cc-ee01-457a-9f57-41046f5b092d",
 "disease": {
  "id": "M2023_04_26_16_38_52",
  "names": [
   "Migraine"
  ],
  "dbLinks": {
   "icd10": [
    "G43"
   ],
   "icd11": [
    "8A80"
   ],
   "mesh": [
    "C10.228.140.546.399.750"
   ]
  },
  "description": "Migraine is a chronic neurological disorder characterized by recurrent episodes of unilateral, pulsatile headaches associated with autonomic symptoms such as nausea, vomiting, photophobia, and phonophobia. The pathophysiology of migraine is multifactorial and involves complex interactions between genetic, environmental, and neurochemical factors that modulate cerebral vascular tone and nociception. Migraine attacks can be triggered by a variety of factors, including stress, hormonal changes, sleep disturbances, and certain foods or medications. Treatment options for migraine include pharmacotherapy for acute attacks, preventive medications for frequent or severe headaches, and lifestyle modifications to avoid triggers. In refractory cases, interventional therapies such as nerve blocks or neuromodulation techniques may be considered."
 },
 "article": {
  "id": "3404480",
  "text": "We have studied the association between migraine and major depression in a group of 133 probands with major depression, a group of 82 normal community controls and 400 interviewed first-degree relatives of the probands and controls. There was a significant association between depression and migraine among both the probands and the relatives. We also found that concomitant symptoms of anxiety were prominent among the depressed persons with migraine. Both depression and migraine were strongly familial but their association did not appear to be highly transmissible. Rather, our data suggested that depression may either be a sequela of migraine or the diathesis which results in both migraine and depression."
 },
 "questions": [
  {
   "id": "7b735d6f-646f-4fc8-9831-c696e272cd95",
   "text": "what are the risk factors of Migraine?",
   "answers": [
    {
     "answer_start": 277,
     "text": "depression"
    }
   ]
  }
 ]
}