Striking observation in S/S cells was that tiRNA corresponding to only one Ala isoacceptor (Ala-hGC) exhibited high cleavage duringbothhypertonicandoxidativestress.AlatRNAhasbeen previouslyreportedtoinhibitproteinsynthesisinvitro, butthe specific isoacceptors were not tested (20).
ANG treatment caused higher cleavage of both isoacceptors in S/S cells.