Likewise, most D2 immunogold labeling in dendrites and spines is associ- ated with asymmetric synapses, but is found also outside the PSD at extrasynaptic and perisynaptic sites (Negyessy and Goldman-Rakic 2005).
These data indicate that D1 and D2 receptors are most often associated with asym- metric terminals, which are typically displaced from the PSD in the peri- or extrasynaptic space.