All old individuals from Germany and Italy and nonagenarian from Italy were sorted into a TLR1 negative genotype (743AA/1805GG) group, a heterozygous TLR1pos 743AG/1805TG group and a homozygous TLR1pos 743GG/1805TT group.
The basal cytokine and chemokine levels between the different TLR1 genotype groups were analyzed and compared.