title: Numerical modelling of plasticity induced by Quadri-pulse stimulation

authors: Sorkhabi, Majid Memarian

subjects: Transcranial magnetic stimulation

abstract: Quadri-pulse stimulation (QPS), a type of repetitive transcranial magnetic stimulation (rTMS), can induce a considerable aftereffect on cortical synapses. Human experiments have shown that the type of effect on synaptic efficiency (in terms of potentiation or depression) depends on the time interval between pulses. The maturation of biophysically-based models, which describe the physiological properties of plasticity mathematically, offers a beneficial framework to explore induced plasticity for new stimulation protocols. To model the QPS paradigm, a phenomenological model based on the knowledge of spike timing-dependent plasticity (STDP) mechanisms of synaptic plasticity was utilized where the cortex builds upon the platform of neuronal population modeling. Induced cortical plasticity was modeled for both conventional monophasic pulses and unidirectional pulses generated by the cTMS device, in a total of 117 different scenarios. For the conventional monophasic stimuli, the results of the predictive model broadly follow what is typically seen in human experiments. Unidirectional pulses can produce a similar range of plasticity. Additionally, changing the pulse width had a considerable effect on the plasticity (approximately 20% increase). As the width of the positive phase increases, the size of the potentiation will also increase. The proposed model can generate predictions to guide future plasticity experiments. Estimating the plasticity and optimizing the rTMS protocols might effectively improve the safety implications of TMS experiments by reducing the number of delivered pulses to participants. Finding the optimal stimulation protocol with the maximum potentiation/depression can lead to the design of a new TMS pulse generator device with targeted hardware and control algorithms.

text: Numerical modelling of plasticity induced by Quadri-pulse stimulation Quadri-pulse stimulation (QPS), a type of repetitive transcranial magnetic stimulation (rTMS), can induce a considerable aftereffect on cortical synapses. Human experiments have shown that the type of effect on synaptic efficiency (in terms of potentiation or depression) depends on the time interval between pulses. The maturation of biophysically-based models, which describe the physiological properties of plasticity mathematically, offers a beneficial framework to explore induced plasticity for new stimulation protocols. To model the QPS paradigm, a phenomenological model based on the knowledge of spike timing-dependent plasticity (STDP) mechanisms of synaptic plasticity was utilized where the cortex builds upon the platform of neuronal population modeling. Induced cortical plasticity was modeled for both conventional monophasic pulses and unidirectional pulses generated by the cTMS device, in a total of 117 different scenarios. For the conventional monophasic stimuli, the results of the predictive model broadly follow what is typically seen in human experiments. Unidirectional pulses can produce a similar range of plasticity. Additionally, changing the pulse width had a considerable effect on the plasticity (approximately 20% increase). As the width of the positive phase increases, the size of the potentiation will also increase. The proposed model can generate predictions to guide future plasticity experiments. Estimating the plasticity and optimizing the rTMS protocols might effectively improve the safety implications of TMS experiments by reducing the number of delivered pulses to participants. Finding the optimal stimulation protocol with the maximum potentiation/depression can lead to the design of a new TMS pulse generator device with targeted hardware and control algorithms.

year: 2021

title: Pasifika women affected by domestic violence: The case of Teuila

authors: Masters-Awatere, Bridgette

abstract: Domestic violence is a pervasive social issue in New Zealand, with the majority of victims being women and children. In 2008, the New Zealand Crime and Safety Survey found that one in five Pasifika had experienced violence at the hands of their partner in the previous year.2 Six years later the results of the same survey reported a 19 per cent decrease of intimate partner violence among Pasifika. Despite this reduction, domestic violence is still prevalent in Pasifika communities. Women in general are known to have low rates of accessing the services available to assist them in navigating themselves and their children to safety, and Pasifika women, with even fewer social and economic resources than other women, are thus left in an even more precarious position. The research presented in this chapter focuses on identifying the barriers and supports women encounter when they attempt to access external agency support to gain protection from their abusers in order to deal with the impacts of abuse.

text: Pasifika women affected by domestic violence: The case of Teuila Domestic violence is a pervasive social issue in New Zealand, with the majority of victims being women and children. In 2008, the New Zealand Crime and Safety Survey found that one in five Pasifika had experienced violence at the hands of their partner in the previous year.2 Six years later the results of the same survey reported a 19 per cent decrease of intimate partner violence among Pasifika. Despite this reduction, domestic violence is still prevalent in Pasifika communities. Women in general are known to have low rates of accessing the services available to assist them in navigating themselves and their children to safety, and Pasifika women, with even fewer social and economic resources than other women, are thus left in an even more precarious position. The research presented in this chapter focuses on identifying the barriers and supports women encounter when they attempt to access external agency support to gain protection from their abusers in order to deal with the impacts of abuse.

year: 2017

title: Challenges Faced – Implications for Policy: The Everyday Lives of Eastern European Women in New Zealand

authors: Ember, Adrienna

subjects: everyday life

abstract: This study explored the everyday lives, aspirations, and coping strategies of seven Eastern European immigrant women in New Zealand who came from Bulgaria, the former Eastern Germany, Hungary, Poland, Romania, Serbia, and Slovakia. The answers to the research questions aimed to contribute to the deconstruction of the invisibility and marginalisation of these women in New Zealand.
Guided by the philosophies of Kaupapa Māori Research; the theory of Human Wellbeing; and the theory of Positive Psychology, and using the methods of narrative inquiry, three interviews were conducted with each participant. The focus of the first interviews was to learn about the everyday lives of research participants in their countries of origin. The second interview explored the reasons of relocation to New Zealand, the settlement process, and how women re-established their lives in their new locations. In the final interviews women talked about their current everyday lives and their plans for the future.
Interviews were recorded and summarised in interview summary reports which research participants modified in collaboration with the researcher until a final version was achieved. In addition, women participated in two focus group sessions. The first session was devoted to establish connections among the participants and allow themes to emerge from their conversations. The second group session aimed to explore areas women struggled with in their lives the most: relationships and employment opportunities.
The study yielded contributions to the research topic, to the acculturation literature, and to the design of research with migrants. Firstly, it revealed both negative and positive aspects of the participants’ everyday lives and highlighted some under-researched cultural differences from the mainstream population.
Women highlighted as an important cultural difference their strong preference for straightforward communication which was often experienced as offensive and blatant by local New Zealanders. Research participants critiqued the necessity of networking to obtain jobs in New Zealand which is a clear obstacle for a newly arrived migrant.
This study also highlighted how the acculturation process is more individual and complex than conventional models have sought to explain. While traditional acculturation literature suggests that migrants go through some common patterns during their settlement that ideally leads to their assimilation to the host culture, in this research not all migrant women intended to assimilate. Indeed, those with a stronger wish to become part of the host culture reported more disappointments than those who embraced their cultural otherness as a positive aspect and did not mind reminding different from the dominant Pakeha culture.
Finally, for migrant studies a less common research design was applied by using the Kaupapa Māori framework. This philosophy proposes a research process that empowers immigrants to voice their needs and strengthen them as agents of their lives beyond the research process. While two strength based theories were used for data interpretation (the 3-D model of the Human Wellbeing Theory and the PERMA model of Positive Psychology), the data analysis revealed that both models showed some limitations by failing to incorporate the dimension of spiritual and physical wellbeing within their domains.

text: Challenges Faced – Implications for Policy: The Everyday Lives of Eastern European Women in New Zealand This study explored the everyday lives, aspirations, and coping strategies of seven Eastern European immigrant women in New Zealand who came from Bulgaria, the former Eastern Germany, Hungary, Poland, Romania, Serbia, and Slovakia. The answers to the research questions aimed to contribute to the deconstruction of the invisibility and marginalisation of these women in New Zealand.
Guided by the philosophies of Kaupapa Māori Research; the theory of Human Wellbeing; and the theory of Positive Psychology, and using the methods of narrative inquiry, three interviews were conducted with each participant. The focus of the first interviews was to learn about the everyday lives of research participants in their countries of origin. The second interview explored the reasons of relocation to New Zealand, the settlement process, and how women re-established their lives in their new locations. In the final interviews women talked about their current everyday lives and their plans for the future.
Interviews were recorded and summarised in interview summary reports which research participants modified in collaboration with the researcher until a final version was achieved. In addition, women participated in two focus group sessions. The first session was devoted to establish connections among the participants and allow themes to emerge from their conversations. The second group session aimed to explore areas women struggled with in their lives the most: relationships and employment opportunities.
The study yielded contributions to the research topic, to the acculturation literature, and to the design of research with migrants. Firstly, it revealed both negative and positive aspects of the participants’ everyday lives and highlighted some under-researched cultural differences from the mainstream population.
Women highlighted as an important cultural difference their strong preference for straightforward communication which was often experienced as offensive and blatant by local New Zealanders. Research participants critiqued the necessity of networking to obtain jobs in New Zealand which is a clear obstacle for a newly arrived migrant.
This study also highlighted how the acculturation process is more individual and complex than conventional models have sought to explain. While traditional acculturation literature suggests that migrants go through some common patterns during their settlement that ideally leads to their assimilation to the host culture, in this research not all migrant women intended to assimilate. Indeed, those with a stronger wish to become part of the host culture reported more disappointments than those who embraced their cultural otherness as a positive aspect and did not mind reminding different from the dominant Pakeha culture.
Finally, for migrant studies a less common research design was applied by using the Kaupapa Māori framework. This philosophy proposes a research process that empowers immigrants to voice their needs and strengthen them as agents of their lives beyond the research process. While two strength based theories were used for data interpretation (the 3-D model of the Human Wellbeing Theory and the PERMA model of Positive Psychology), the data analysis revealed that both models showed some limitations by failing to incorporate the dimension of spiritual and physical wellbeing within their domains.

year: 2016