title: Model selection based product kernel learning for regression on graphs

authors: Seeland, Madeleine

subjects: computer science

abstract: The choice of a suitable graph kernel is intrinsically hard and often cannot be made in an informed manner for a given dataset. Methods for multiple kernel learning offer a possible remedy, as they combine and weight kernels on the basis of a labeled training set of molecules to define a new kernel. Whereas most methods for multiple kernel learning focus on learning convex linear combinations of kernels, we propose to combine kernels in products, which theoretically enables higher expressiveness. In experiments on ten publicly available chemical QSAR datasets we show that product kernel learning is on no dataset significantly worse than any of the competing kernel methods and on average the best method available. A qualitative analysis of the resulting product kernels shows how the results vary from dataset to dataset.

text: Model selection based product kernel learning for regression on graphs The choice of a suitable graph kernel is intrinsically hard and often cannot be made in an informed manner for a given dataset. Methods for multiple kernel learning offer a possible remedy, as they combine and weight kernels on the basis of a labeled training set of molecules to define a new kernel. Whereas most methods for multiple kernel learning focus on learning convex linear combinations of kernels, we propose to combine kernels in products, which theoretically enables higher expressiveness. In experiments on ten publicly available chemical QSAR datasets we show that product kernel learning is on no dataset significantly worse than any of the competing kernel methods and on average the best method available. A qualitative analysis of the resulting product kernels shows how the results vary from dataset to dataset.

year: 2013

title: The inherent liminality of lesbian detectives: Shifting spaces and lesbian crime fiction 1984-2022

authors: Antoniolli, Claudia

subjects: Crime fiction

abstract: This thesis studies lesbian detective fiction and specifically considers this genre in its early decades (1980s-1990s) from the United States, United Kingdom, Australia, and New Zealand. This thesis postulates that out of a sample pool of a hundred novels, there are recurring patterns of behaviours and attitudes among the protagonists of this genre within certain physical and metaphorical spaces. These patterns demonstrate a destabilised identity, as the lesbian sleuth never ceases to explore and test the boundaries of her authority as an enforcer of law and order and of her suppressed spatiality as a member of a sexual minority. This causes her to live in a perpetual state of Insider/Outsider liminality and it causes queer trauma to be a fundamental aspect of her character. This thesis considers this concept as the result of long-standing, systemic homophobia and heterosexist normativity, and utilises the notion of queer trauma to interpret the way the lesbian sleuth is inescapably stuck between a sense of duty and justice and a yearning for belonging and self-affirmation. The interpretive process is supported by an extensive and in-depth theoretical research into the fields of history, culture, geography, feminist criticism, gender, and sexuality studies for the selected subject matter. The spaces selected and analysed in this thesis are the queer closet, the medical establishment, domestic settings, and the gay bar. These spaces have been chosen for the significant, emblematic ways in which the lesbian detectives interact with them and have been analysed in order of their importance for the protagonists’ characterisation. The introduction includes introductory statements and the theoretical framework, the first chapter overviews major detectives in the history of crime literature from a spatial perspective; the second chapter discusses the queer closet; the third chapter considers the space of the clinic and the topics of queer trauma and of the pathologisation of homosexuality; the fourth chapter analyses the domestic settings of the protagonists; the fifth chapter examines the context of the gay bar and its history; finally, the conclusion offers closing statements about the focus and originality of this thesis. The originality of this thesis lies in its focus on spaces and on the relationship between the protagonist and society, law and order, and Self and Other. This thesis contributes to the knowledge of queer literature by specifically considering the unescapable liminality of the lesbian/Outsider detective/Insider.

text: The inherent liminality of lesbian detectives: Shifting spaces and lesbian crime fiction 1984-2022 This thesis studies lesbian detective fiction and specifically considers this genre in its early decades (1980s-1990s) from the United States, United Kingdom, Australia, and New Zealand. This thesis postulates that out of a sample pool of a hundred novels, there are recurring patterns of behaviours and attitudes among the protagonists of this genre within certain physical and metaphorical spaces. These patterns demonstrate a destabilised identity, as the lesbian sleuth never ceases to explore and test the boundaries of her authority as an enforcer of law and order and of her suppressed spatiality as a member of a sexual minority. This causes her to live in a perpetual state of Insider/Outsider liminality and it causes queer trauma to be a fundamental aspect of her character. This thesis considers this concept as the result of long-standing, systemic homophobia and heterosexist normativity, and utilises the notion of queer trauma to interpret the way the lesbian sleuth is inescapably stuck between a sense of duty and justice and a yearning for belonging and self-affirmation. The interpretive process is supported by an extensive and in-depth theoretical research into the fields of history, culture, geography, feminist criticism, gender, and sexuality studies for the selected subject matter. The spaces selected and analysed in this thesis are the queer closet, the medical establishment, domestic settings, and the gay bar. These spaces have been chosen for the significant, emblematic ways in which the lesbian detectives interact with them and have been analysed in order of their importance for the protagonists’ characterisation. The introduction includes introductory statements and the theoretical framework, the first chapter overviews major detectives in the history of crime literature from a spatial perspective; the second chapter discusses the queer closet; the third chapter considers the space of the clinic and the topics of queer trauma and of the pathologisation of homosexuality; the fourth chapter analyses the domestic settings of the protagonists; the fifth chapter examines the context of the gay bar and its history; finally, the conclusion offers closing statements about the focus and originality of this thesis. The originality of this thesis lies in its focus on spaces and on the relationship between the protagonist and society, law and order, and Self and Other. This thesis contributes to the knowledge of queer literature by specifically considering the unescapable liminality of the lesbian/Outsider detective/Insider.

year: 2023

title: Pūrākau, death, and assisted dying: A Māori framework for understanding end-of-life

authors: Karaka-Clarke, Te Hurinui

subjects: Pūrākau, Assisted Dying, Tikanga Māori, Mōair Cosmology, End of Life: Ethics, Mana Motuhake, Wairua, Whakapapa, Relational Autonomy

abstract: This conceptual article addresses several critical gaps in health literature by exploring the ethical, spiritual, and cultural dimensions of assisted dying through the lens of Tikanga Māori and pūrākau (ancestral narratives).  While existing end-of-life policy frameworks often prioritize Western bioethical principles, this article argues for the inclusion of Kaupapa Māori principles such as whakapapa, wairua, mana motuhake, and tapu/ noa as essential components of culturally resonant care.    Drawing upon foundational narratives including the separation of  Ranginui and Papatūānuku, the creation of Hineahuone, the transformation of Hinetītama into Hinenuitepō, and the fatal attempt of Māui to conquer death, we position pūrākau as dynamic ethical texts that guide decision-making.  This article contributes to Indigenous health discourse by offering a whānau-centred, tikanga-informed critique of the End-of-Life Choice Act 2019 and calls for broader recognition of spiritual and relational dimensions in end-of-life care.   We contend that, when under-taken with whānau engagement, spiritual awareness, and cultural integrity, may be ethically compatible with tikanga Māori

text: Pūrākau, death, and assisted dying: A Māori framework for understanding end-of-life This conceptual article addresses several critical gaps in health literature by exploring the ethical, spiritual, and cultural dimensions of assisted dying through the lens of Tikanga Māori and pūrākau (ancestral narratives).  While existing end-of-life policy frameworks often prioritize Western bioethical principles, this article argues for the inclusion of Kaupapa Māori principles such as whakapapa, wairua, mana motuhake, and tapu/ noa as essential components of culturally resonant care.    Drawing upon foundational narratives including the separation of  Ranginui and Papatūānuku, the creation of Hineahuone, the transformation of Hinetītama into Hinenuitepō, and the fatal attempt of Māui to conquer death, we position pūrākau as dynamic ethical texts that guide decision-making.  This article contributes to Indigenous health discourse by offering a whānau-centred, tikanga-informed critique of the End-of-Life Choice Act 2019 and calls for broader recognition of spiritual and relational dimensions in end-of-life care.   We contend that, when under-taken with whānau engagement, spiritual awareness, and cultural integrity, may be ethically compatible with tikanga Māori

year: 2025-09-24