title: Structural insight into DNA joining: from conserved mechanisms to diverse scaffolds.

authors: Williamson, Adele

abstract: DNA ligases are diverse enzymes with essential functions in replication and repair of DNA; here we review recent advances in their structure and distribution and discuss how this contributes to understanding their biological roles and technological potential. Recent high-resolution crystal structures of DNA ligases from different organisms, including DNA-bound states and reaction intermediates, have provided considerable insight into their enzymatic mechanism and substrate interactions. All cellular organisms possess at least one DNA ligase, but many species encode multiple forms some of which are modular multifunctional enzymes. New experimental evidence for participation of DNA ligases in pathways with additional DNA modifying enzymes is defining their participation in non-redundant repair processes enabling elucidation of their biological functions. Coupled with identification of a wealth of DNA ligase sequences through genomic data, our increased appreciation of the structural diversity and phylogenetic distribution of DNA ligases has the potential to uncover new biotechnological tools and provide new treatment options for bacterial pathogens.

text: Structural insight into DNA joining: from conserved mechanisms to diverse scaffolds. DNA ligases are diverse enzymes with essential functions in replication and repair of DNA; here we review recent advances in their structure and distribution and discuss how this contributes to understanding their biological roles and technological potential. Recent high-resolution crystal structures of DNA ligases from different organisms, including DNA-bound states and reaction intermediates, have provided considerable insight into their enzymatic mechanism and substrate interactions. All cellular organisms possess at least one DNA ligase, but many species encode multiple forms some of which are modular multifunctional enzymes. New experimental evidence for participation of DNA ligases in pathways with additional DNA modifying enzymes is defining their participation in non-redundant repair processes enabling elucidation of their biological functions. Coupled with identification of a wealth of DNA ligase sequences through genomic data, our increased appreciation of the structural diversity and phylogenetic distribution of DNA ligases has the potential to uncover new biotechnological tools and provide new treatment options for bacterial pathogens.

year: 2020

title: Strike ballots: The New Zealand experience

authors: Wilson, Margaret

abstract: This article analyses the legal history of strikes in New Zealand and in particular the role of strike ballots within the statutory framework. The principal focus is on the current legislative requirements, but the role of the strike in employment relations since 1894 is analysed in order to locate the current legislative provision in the context of the role of the state in the regulation of trade unions.

text: Strike ballots: The New Zealand experience This article analyses the legal history of strikes in New Zealand and in particular the role of strike ballots within the statutory framework. The principal focus is on the current legislative requirements, but the role of the strike in employment relations since 1894 is analysed in order to locate the current legislative provision in the context of the role of the state in the regulation of trade unions.

year: 2016

title: The anthropologist as tribal advocate

authors: Hopa, Ngapare K

subjects: economic conditions

abstract: My colleague has outlined some of the major issues facing New Zealand and its indigenous Polynesians - the Maaori - who not so long ago were ranked among the most documented in the world and the country as THE laboratory of race relations.
The present disadvantaged and dependent status of Maaori people show how illusory that notion is and, for New Zealand anthropologists, the challenge it presents in helping Maaori to attain socio-economic sovereignty within the 'partnership' promised by the Treaty of Waitangi.
In the late 60s and since, a few 'radical' mostly 'native' anthropologists can be said to have risen to the challenge that Gough (1968) and others, laid down, but it cannot be said, even now, that the profession as a whole in New Zealand, has been responsive.
Perhaps it is still committed to the myth of scientific objectivity, or, after regarding themselves as champions of a powerless and marginal people, has not recovered from the accusation of impotency during the social ferment of the 70s and since. To be fair, there were a few individuals who were allied with the protest movement but whose contributions were not acknowledged. They rode out the storm however and have continued to contribute significantly to the Maaori cause.

text: The anthropologist as tribal advocate My colleague has outlined some of the major issues facing New Zealand and its indigenous Polynesians - the Maaori - who not so long ago were ranked among the most documented in the world and the country as THE laboratory of race relations.
The present disadvantaged and dependent status of Maaori people show how illusory that notion is and, for New Zealand anthropologists, the challenge it presents in helping Maaori to attain socio-economic sovereignty within the 'partnership' promised by the Treaty of Waitangi.
In the late 60s and since, a few 'radical' mostly 'native' anthropologists can be said to have risen to the challenge that Gough (1968) and others, laid down, but it cannot be said, even now, that the profession as a whole in New Zealand, has been responsive.
Perhaps it is still committed to the myth of scientific objectivity, or, after regarding themselves as champions of a powerless and marginal people, has not recovered from the accusation of impotency during the social ferment of the 70s and since. To be fair, there were a few individuals who were allied with the protest movement but whose contributions were not acknowledged. They rode out the storm however and have continued to contribute significantly to the Maaori cause.

year: 1988