title: Obesity and breast cancer outcomes in chemotherapy patients in New Zealand - a population-based cohort study

authors: Elwood, J. Mark

subjects: Breast cancer

abstract: Background: Obesity has been reported as an adverse prognostic factor in breast cancer, but inconsistently, and under-treatment with chemotherapy may occur. We provide the first assessment of obesity and breast cancer outcomes in a population-based, multi-ethnic cohort of New Zealand patients treated with chemotherapy.
Methods: All 3536 women diagnosed with invasive breast cancer in the Waikato region of New Zealand from 2000-2014 were registered and followed until last follow-up in specialist or primary care, death or Dec 2014; median follow-up 4.1 years. For the 1049 patients receiving chemotherapy, mortality from breast cancer, other causes, and all causes, and rates of loco-regional and of distant recurrence, were assessed by body mass index (BMI), recorded after diagnosis, adjusting for other clinico-pathological and demographic factors by Cox regression.
Results: BMI was known for 98% (n=1049); 33% were overweight (BMI 25-29.9), 21% were obese (BMI 30-34.9), and 14% were very obese (BMI 35+). There were no significant associations between obesity and survival, after adjustment for demographic and clinical factors (hazard ratios, HR, for very obese compared to BMI 21-24, for breast cancer deaths 0.96 (0.56-1.67), and for all deaths 1.03 (0.63-1.67), respectively, and only small non-significant associations for loco-regional or metastatic recurrence rates (HR 1.17 and 1.33 respectively). Subgroup analyses by age, menopausal status, ethnicity, stage, post-surgical radiotherapy, mode of diagnosis, type of surgery, and receptor status, showed no associations. No associations were seen with BMI as a continuous variable. The results in all patients irrespective of treatment but with recorded BMI data (n=2296) showed similar results.
Conclusions: In this population, obesity assessed post-diagnosis had no effect on survival or recurrence, based on 1049 patients with chemotherapy treatment with follow-up up to 14 years.

text: Obesity and breast cancer outcomes in chemotherapy patients in New Zealand - a population-based cohort study Background: Obesity has been reported as an adverse prognostic factor in breast cancer, but inconsistently, and under-treatment with chemotherapy may occur. We provide the first assessment of obesity and breast cancer outcomes in a population-based, multi-ethnic cohort of New Zealand patients treated with chemotherapy.
Methods: All 3536 women diagnosed with invasive breast cancer in the Waikato region of New Zealand from 2000-2014 were registered and followed until last follow-up in specialist or primary care, death or Dec 2014; median follow-up 4.1 years. For the 1049 patients receiving chemotherapy, mortality from breast cancer, other causes, and all causes, and rates of loco-regional and of distant recurrence, were assessed by body mass index (BMI), recorded after diagnosis, adjusting for other clinico-pathological and demographic factors by Cox regression.
Results: BMI was known for 98% (n=1049); 33% were overweight (BMI 25-29.9), 21% were obese (BMI 30-34.9), and 14% were very obese (BMI 35+). There were no significant associations between obesity and survival, after adjustment for demographic and clinical factors (hazard ratios, HR, for very obese compared to BMI 21-24, for breast cancer deaths 0.96 (0.56-1.67), and for all deaths 1.03 (0.63-1.67), respectively, and only small non-significant associations for loco-regional or metastatic recurrence rates (HR 1.17 and 1.33 respectively). Subgroup analyses by age, menopausal status, ethnicity, stage, post-surgical radiotherapy, mode of diagnosis, type of surgery, and receptor status, showed no associations. No associations were seen with BMI as a continuous variable. The results in all patients irrespective of treatment but with recorded BMI data (n=2296) showed similar results.
Conclusions: In this population, obesity assessed post-diagnosis had no effect on survival or recurrence, based on 1049 patients with chemotherapy treatment with follow-up up to 14 years.

year: 2018

title: Government regulation in the Australian popular music industry: The rhetoric of cultural protection, the reality of economic production

authors: McLeay, Colin

subjects: Australia

abstract: In the 1990s the artistic autonomy of the territorial subsidiaries of the major record companies increased. Local scale “cultural freedom” did not mitigate the role of national regulation, with the music industry remaining bound by regulation imposed by agencies representing nation-states. National-scale policy rhetoric highlighting the need for “cultural protection” focused attention away from an interest in the economics of popular music, a balance evident in policies of Australian federal governments. In seeking to increase the export potential of locally produced music, Australian governments have come to hold an important place in the political economy of contemporary Australian music.

text: Government regulation in the Australian popular music industry: The rhetoric of cultural protection, the reality of economic production In the 1990s the artistic autonomy of the territorial subsidiaries of the major record companies increased. Local scale “cultural freedom” did not mitigate the role of national regulation, with the music industry remaining bound by regulation imposed by agencies representing nation-states. National-scale policy rhetoric highlighting the need for “cultural protection” focused attention away from an interest in the economics of popular music, a balance evident in policies of Australian federal governments. In seeking to increase the export potential of locally produced music, Australian governments have come to hold an important place in the political economy of contemporary Australian music.

year: 2006

title: Grounding the state of exception in New Zealand: A case study of racial segregation in Pukekohe, Whiteness and the Carceral State

authors: Martin, Jessica

subjects: State of exception

abstract: Indigenous scholars in settler-colonial contexts have highlighted the hyper-imprisonment of Indigenous people, locating it as an extension of the colonial project. Although research on this issue in New Zealand is emerging, there is a notable gap in understanding how the carceral state has developed within this particular context. This study aims to address the following research question: How does the historical context of racial segregation in Pukekohe contribute to our understanding of the mechanisms of the carceral state in New Zealand?
To thoroughly examine the hyper-imprisonment of Māori, it is essential to unpack the historical origins of state violence. Despite existing research establishing a link between Māori over-representation in prisons and the enduring effects of colonisation, there is a lack of studies exploring the complex interplay among the carceral state, whiteness, policy, policing, and law, which collectively shape the current landscape of incarceration. This study focuses on the racial segregation in Pukekohe between 1920 and 1960 and utilises reflexive thematic analysis within a case study framework, drawing on the insights offered by Robert Bartholomew's book, No Māori Allowed (2020). The analysis centres on the theoretical concept of the state of exception, shedding light on how power was wielded by the white racial polity. Thus, providing a unique perspective on the carceral state and state-sanctioned violence.
The findings highlight the interconnectedness of various systemic control mechanisms employed by the carceral state. Housing, policing, and whiteness emerge as crucial factors in the control and confinement of Māori in Pukekohe. By emphasising the role of whiteness in suppressing this history, this study underscores the need for critical examination and recognition of white cultural imperialism as a fundamental pillar of the carceral state. Overall, this research offers significant insights into the construction of a targeted population and the enduring consequences of state-sanctioned violence, emphasising the importance of a comprehensive examination of New Zealand's racialised history in discussions on the hyper-imprisonment of Māori.

text: Grounding the state of exception in New Zealand: A case study of racial segregation in Pukekohe, Whiteness and the Carceral State Indigenous scholars in settler-colonial contexts have highlighted the hyper-imprisonment of Indigenous people, locating it as an extension of the colonial project. Although research on this issue in New Zealand is emerging, there is a notable gap in understanding how the carceral state has developed within this particular context. This study aims to address the following research question: How does the historical context of racial segregation in Pukekohe contribute to our understanding of the mechanisms of the carceral state in New Zealand?
To thoroughly examine the hyper-imprisonment of Māori, it is essential to unpack the historical origins of state violence. Despite existing research establishing a link between Māori over-representation in prisons and the enduring effects of colonisation, there is a lack of studies exploring the complex interplay among the carceral state, whiteness, policy, policing, and law, which collectively shape the current landscape of incarceration. This study focuses on the racial segregation in Pukekohe between 1920 and 1960 and utilises reflexive thematic analysis within a case study framework, drawing on the insights offered by Robert Bartholomew's book, No Māori Allowed (2020). The analysis centres on the theoretical concept of the state of exception, shedding light on how power was wielded by the white racial polity. Thus, providing a unique perspective on the carceral state and state-sanctioned violence.
The findings highlight the interconnectedness of various systemic control mechanisms employed by the carceral state. Housing, policing, and whiteness emerge as crucial factors in the control and confinement of Māori in Pukekohe. By emphasising the role of whiteness in suppressing this history, this study underscores the need for critical examination and recognition of white cultural imperialism as a fundamental pillar of the carceral state. Overall, this research offers significant insights into the construction of a targeted population and the enduring consequences of state-sanctioned violence, emphasising the importance of a comprehensive examination of New Zealand's racialised history in discussions on the hyper-imprisonment of Māori.

year: 2024