title: Ethical, legal, and social issues in the Earth BioGenome Project.

authors: Sherkow, Jacob S.

subjects: EBP

abstract: The Earth BioGenome Project (EBP) is an audacious endeavor to obtain whole-genome sequences of representatives from all eukaryotic species on Earth. In addition to the project's technical and organizational challenges, it also faces complicated ethical, legal, and social issues. This paper, from members of the EBP's Ethical, Legal, and Social Issues (ELSI) Committee, catalogs these ELSI concerns arising from EBP. These include legal issues, such as sample collection and permitting; the applicability of international treaties, such as the Convention on Biological Diversity and the Nagoya Protocol; intellectual property; sample accessioning; and biosecurity and ethical issues, such as sampling from the territories of Indigenous peoples and local communities, the protection of endangered species, and cross-border collections, among several others. We also comment on the intersection of digital sequence information and data rights. More broadly, this list of ethical, legal, and social issues for large-scale genomic sequencing projects may be useful in the consideration of ethical frameworks for future projects. While we do not-and cannot-provide simple, overarching solutions for all the issues raised here, we conclude our perspective by beginning to chart a path forward for EBP's work.

text: Ethical, legal, and social issues in the Earth BioGenome Project. The Earth BioGenome Project (EBP) is an audacious endeavor to obtain whole-genome sequences of representatives from all eukaryotic species on Earth. In addition to the project's technical and organizational challenges, it also faces complicated ethical, legal, and social issues. This paper, from members of the EBP's Ethical, Legal, and Social Issues (ELSI) Committee, catalogs these ELSI concerns arising from EBP. These include legal issues, such as sample collection and permitting; the applicability of international treaties, such as the Convention on Biological Diversity and the Nagoya Protocol; intellectual property; sample accessioning; and biosecurity and ethical issues, such as sampling from the territories of Indigenous peoples and local communities, the protection of endangered species, and cross-border collections, among several others. We also comment on the intersection of digital sequence information and data rights. More broadly, this list of ethical, legal, and social issues for large-scale genomic sequencing projects may be useful in the consideration of ethical frameworks for future projects. While we do not-and cannot-provide simple, overarching solutions for all the issues raised here, we conclude our perspective by beginning to chart a path forward for EBP's work.

year: 2022

title: A study of polyvinyl butyryl based binder system in titanium based metal injection moulding

authors: Thavanayagam, Gnanavinthan

subjects: Binders

abstract: Metal injection moulding (MIM) is an innovative injection moulding technique widely used to produce complex shaped components from feedstock composed of metal powders and thermosetting or thermoplastic binders. In MIM, binder selection and formulation are considered as critical processes since binder characteristics dictate the success of MIM. The purpose of this study is to determine the feasibility of polyvinyl butyryl (PVB) based binder system in Ti-6Al-4V(wt.%)/binder feedstock, as well as to understand the effects of key parameters, such as powder loading and mixing conditions on the rheological properties of a feedstock. In this study, PVB, polyethylene glycol (PEG), and stearic acid (SA) were chosen to formulate a multi-component binder system to prepare Ti-6Al-4V based feedstock with the aid of three types of mixers: a compounder, a modified mechanical mixer and a twin screw extruder. Further, morphological analysis was performed using optical microscopy and scanning electron microscopy. Thermal analysis was performed using simultaneous differential thermal analysis and thermogravimetric analysis. Results showed that binder formulation was reasonably successful with the aid of both mechanical mixer and a twin screw extruder under certain mixing conditions, and the critical powder loading was 68 vol.%, resulting in an optimum powder loading of 63 vol.%.

text: A study of polyvinyl butyryl based binder system in titanium based metal injection moulding Metal injection moulding (MIM) is an innovative injection moulding technique widely used to produce complex shaped components from feedstock composed of metal powders and thermosetting or thermoplastic binders. In MIM, binder selection and formulation are considered as critical processes since binder characteristics dictate the success of MIM. The purpose of this study is to determine the feasibility of polyvinyl butyryl (PVB) based binder system in Ti-6Al-4V(wt.%)/binder feedstock, as well as to understand the effects of key parameters, such as powder loading and mixing conditions on the rheological properties of a feedstock. In this study, PVB, polyethylene glycol (PEG), and stearic acid (SA) were chosen to formulate a multi-component binder system to prepare Ti-6Al-4V based feedstock with the aid of three types of mixers: a compounder, a modified mechanical mixer and a twin screw extruder. Further, morphological analysis was performed using optical microscopy and scanning electron microscopy. Thermal analysis was performed using simultaneous differential thermal analysis and thermogravimetric analysis. Results showed that binder formulation was reasonably successful with the aid of both mechanical mixer and a twin screw extruder under certain mixing conditions, and the critical powder loading was 68 vol.%, resulting in an optimum powder loading of 63 vol.%.

year: 2012

title: Integrating Maori perspectives into community resilience frameworks for the built environment

authors: Boston, Megan

abstract: Many governments and organisations have attempted to construct frameworks for improving community resilience, particularly as related to the built environment. Many frameworks, globally and locally, take a large overview of society and miss the potential to incorporate cultural, social, and engineering practices followed by indigenous people. However, there is much to learn from the traditional practices of Maori that could directly improve community resilience after a disaster. To date, little research has worked on integrating Maori cultural views into resilience frameworks. Using survey and interview data investigating Maori cultural views on resilience and aspects of the built environment, five Maori values were identified to strengthen resilience. These values are matauranga (knowledge), kotahitanga (unity), kaitiakitanga (guardianship), whakawhanaungatanga (relationships), and manakitanga (extending love). Further, communities can increase community cohesion and unity through adapting building and community layouts learned from observing traditional Maori practices, such as a central marae.

text: Integrating Maori perspectives into community resilience frameworks for the built environment Many governments and organisations have attempted to construct frameworks for improving community resilience, particularly as related to the built environment. Many frameworks, globally and locally, take a large overview of society and miss the potential to incorporate cultural, social, and engineering practices followed by indigenous people. However, there is much to learn from the traditional practices of Maori that could directly improve community resilience after a disaster. To date, little research has worked on integrating Maori cultural views into resilience frameworks. Using survey and interview data investigating Maori cultural views on resilience and aspects of the built environment, five Maori values were identified to strengthen resilience. These values are matauranga (knowledge), kotahitanga (unity), kaitiakitanga (guardianship), whakawhanaungatanga (relationships), and manakitanga (extending love). Further, communities can increase community cohesion and unity through adapting building and community layouts learned from observing traditional Maori practices, such as a central marae.

year: 2022