title: Molecular and mesoscale structures in hydrophobically driven aqueous solutions

authors: Finney, John L.

subjects: non-polar interactions

abstract: Since Kauzmann's seminal 1959 paper, the hydrophobic interaction has dominated thinking on the forces that control protein folding and stability. Despite its wide importance in chemistry and biology, our understanding of this interaction at the molecular level remains poor, with little experimental evidence to support the idea of water ordering close to a non-polar group that is at the centre of the standard model for the source of the entropic driving force. Developments over recent years in neutron techniques now enable us to see directly how a non-polar group actually affects the molecular structure of the water in its immediate neighbourhood. On the basis of such work on aqueous solutions of small alcohols, the generally accepted standard model is found to be wanting, and alternative sources of the entropic driving force are suggested. Moreover, the fact that we can now follow changes in hydrogen bonding as the alcohol concentration is varied gives us the possibility of explaining the concentration dependence of the enthalpy of mixing. Complementary studies of solute association on the mesoscopic scale show a rich concentration and temperature behaviour, which reflects a complex balance of polar and non-polar interactions. Unravelling the detailed nature of this balance in simple aqueous amphiphiles may lead to a better understanding of the forces that control biomolecular structural stability and interactions.

text: Molecular and mesoscale structures in hydrophobically driven aqueous solutions Since Kauzmann's seminal 1959 paper, the hydrophobic interaction has dominated thinking on the forces that control protein folding and stability. Despite its wide importance in chemistry and biology, our understanding of this interaction at the molecular level remains poor, with little experimental evidence to support the idea of water ordering close to a non-polar group that is at the centre of the standard model for the source of the entropic driving force. Developments over recent years in neutron techniques now enable us to see directly how a non-polar group actually affects the molecular structure of the water in its immediate neighbourhood. On the basis of such work on aqueous solutions of small alcohols, the generally accepted standard model is found to be wanting, and alternative sources of the entropic driving force are suggested. Moreover, the fact that we can now follow changes in hydrogen bonding as the alcohol concentration is varied gives us the possibility of explaining the concentration dependence of the enthalpy of mixing. Complementary studies of solute association on the mesoscopic scale show a rich concentration and temperature behaviour, which reflects a complex balance of polar and non-polar interactions. Unravelling the detailed nature of this balance in simple aqueous amphiphiles may lead to a better understanding of the forces that control biomolecular structural stability and interactions.

year: 2003-09

title: Harnessing the temporal and projective attributes of human agency to promote anticipatory climate change adaptation

authors: Serrao-Neumann, Silvia

abstract: Human agency is seen as a critical component of adaptive capacity concerning environmental change. This capacity may entail social actor's ability to learn from past experience, and create opportunities in the present for dealing with uncertainty and change in the future. However, it also means that actors need to be able to overturn structural barriers that impede anticipatory adaptation to climate change such as lack of political leadership, power imbalances, acceptance of climate risks and willingness to act. While scholarship around questions of structural barriers is common in environmental studies literature, there is less understanding about how future thinking could help to strengthen human agency. Harnessing the temporal and projective attributes of human agency by which social actors can exert influence over the future and create solutions may comprise a promising way forward. This paper investigates how social actors understand past social and environmental change and explores how scenario planning may help actors apply their understanding of changes over time to devise policies for climate change adaptation. The paper applies this exploratory lens to an Australian coastal local government area engaged in scenario planning and adaptation pathways planning. Findings indicate that the temporality aspect of agency applied to solving complex issues and overcoming structural barriers manifests differently from an individual to a collective perspective. This means that while scenario planning and adaptation pathways planning helps with anticipatory identification and experimentation, this may not be sufficient to overturn structural barriers to adaptation in the short-term.

text: Harnessing the temporal and projective attributes of human agency to promote anticipatory climate change adaptation Human agency is seen as a critical component of adaptive capacity concerning environmental change. This capacity may entail social actor's ability to learn from past experience, and create opportunities in the present for dealing with uncertainty and change in the future. However, it also means that actors need to be able to overturn structural barriers that impede anticipatory adaptation to climate change such as lack of political leadership, power imbalances, acceptance of climate risks and willingness to act. While scholarship around questions of structural barriers is common in environmental studies literature, there is less understanding about how future thinking could help to strengthen human agency. Harnessing the temporal and projective attributes of human agency by which social actors can exert influence over the future and create solutions may comprise a promising way forward. This paper investigates how social actors understand past social and environmental change and explores how scenario planning may help actors apply their understanding of changes over time to devise policies for climate change adaptation. The paper applies this exploratory lens to an Australian coastal local government area engaged in scenario planning and adaptation pathways planning. Findings indicate that the temporality aspect of agency applied to solving complex issues and overcoming structural barriers manifests differently from an individual to a collective perspective. This means that while scenario planning and adaptation pathways planning helps with anticipatory identification and experimentation, this may not be sufficient to overturn structural barriers to adaptation in the short-term.

year: 2022

title: He Maimai Aroha mō Nātana Waka Takurua

authors: Manuirirangi, Hōri

subjects: Poroporoaki

abstract: He kupu whakamānawa nā Hōri Manuirirangi ki a Nātana Waka Takurua i tana matenga.

text: He Maimai Aroha mō Nātana Waka Takurua He kupu whakamānawa nā Hōri Manuirirangi ki a Nātana Waka Takurua i tana matenga.

year: 2012-05