title: Strategies to manage aquatic plants

authors: de Winton, Mary

abstract: I am the first of three presenters this afternoon who are going to focus on aquatic weed management. I have the title Strategies to Manage Aquatic Plants - Towards Shared Understanding and I know what you are all thinking, ‘Strategies’ is not the kind of buzz word of the century but I am hoping to convey why we need agreed strategies, specifically an articulated strategy for lake weed management.

text: Strategies to manage aquatic plants I am the first of three presenters this afternoon who are going to focus on aquatic weed management. I have the title Strategies to Manage Aquatic Plants - Towards Shared Understanding and I know what you are all thinking, ‘Strategies’ is not the kind of buzz word of the century but I am hoping to convey why we need agreed strategies, specifically an articulated strategy for lake weed management.

year: 2017

title: Aconitine induces prolonged seizure-like events in rat neocortical brain slices

authors: Voss, Logan J.

subjects: cerebral cortex

abstract: Aconitine effects on the hippocampal slice preparation have been well documented and include acute inhibitory and prolonged excitatory effects. To date, the effect of aconitine on neocortical activity has not been investigated. The aim of this study was to characterise the acute and long term effects of aconitine on cortical local field potential activity. Neocortical slices from juvenile Sprague–Dawley rats were perfused at room temperature with aconitine in normal artificial cerebrospinal fluid (aCSF) (n = 10). Spontaneous local field potential activity was recorded from the somatosensory cortex. The calcium dependence of aconitine-induced activity was investigated using low-calcium aCSF (n = 8). To isolate sodium and N-methyl-d-aspartate (NMDA) channel effects, phenytoin (n = 4) and 2-amino-5-phosphono-pentanoic acid (APV) (n = 6) were co-administered with aconitine, respectively. Aconitine consistently induced a dramatic increase in population “spike” activity after prolonged (89.5 ± 36.6 min) application in normal aCSF. This activity surge was eliminated in low-calcium aCSF and when aconitine was co-administered with phenytoin and APV. The acute effects of aconitine application were variable and included an increase in the frequency of population spikes, appearance of oscillatory seizure-like activity and prolonged bursts of multiunit activity. No acute inhibitory effects were observed. Aconitine has acute and prolonged excitatory effects on neocortical activity. The latter is effected by calcium-dependent mechanisms, in keeping with known effects of aconitine on hippocampal slices. Both sodium and NMDA channels are involved in mediating the calcium-dependent aconitine effects.

text: Aconitine induces prolonged seizure-like events in rat neocortical brain slices Aconitine effects on the hippocampal slice preparation have been well documented and include acute inhibitory and prolonged excitatory effects. To date, the effect of aconitine on neocortical activity has not been investigated. The aim of this study was to characterise the acute and long term effects of aconitine on cortical local field potential activity. Neocortical slices from juvenile Sprague–Dawley rats were perfused at room temperature with aconitine in normal artificial cerebrospinal fluid (aCSF) (n = 10). Spontaneous local field potential activity was recorded from the somatosensory cortex. The calcium dependence of aconitine-induced activity was investigated using low-calcium aCSF (n = 8). To isolate sodium and N-methyl-d-aspartate (NMDA) channel effects, phenytoin (n = 4) and 2-amino-5-phosphono-pentanoic acid (APV) (n = 6) were co-administered with aconitine, respectively. Aconitine consistently induced a dramatic increase in population “spike” activity after prolonged (89.5 ± 36.6 min) application in normal aCSF. This activity surge was eliminated in low-calcium aCSF and when aconitine was co-administered with phenytoin and APV. The acute effects of aconitine application were variable and included an increase in the frequency of population spikes, appearance of oscillatory seizure-like activity and prolonged bursts of multiunit activity. No acute inhibitory effects were observed. Aconitine has acute and prolonged excitatory effects on neocortical activity. The latter is effected by calcium-dependent mechanisms, in keeping with known effects of aconitine on hippocampal slices. Both sodium and NMDA channels are involved in mediating the calcium-dependent aconitine effects.

year: 2008

title: The Unmet Legal, Social and Cultural Needs of Māori with Disabilities

authors: Hickey, Susan Jane

subjects: Māori

abstract: There is little work done in the area of indigenous disability identity issues and how they are recognised in domestic and international human rights laws. The discourse of disability has always been based on social constructionism and without it, there is no identity. I discuss its relevance to indigenous (Māori) with disabilities and how the multiplicitous nature of the identity of  other  has a particular impact when indigenous, gender and disability are all identified from marginalised groups. I also explore the impact of westernised thinking around impairment, in particular the models of disabilities on indigenous well-being. The issues of family (whānau), whakawhanaungatanga (family relationships), interdependence (community) and collectivity identities central to indigenous thinking are largely ignored by law and policy, yet central to indigenous identity. This ignorance in policy has led to the disparities that continue to remain for indigenous persons with disabilities, particularly those from within thematic identity groups.

text: The Unmet Legal, Social and Cultural Needs of Māori with Disabilities There is little work done in the area of indigenous disability identity issues and how they are recognised in domestic and international human rights laws. The discourse of disability has always been based on social constructionism and without it, there is no identity. I discuss its relevance to indigenous (Māori) with disabilities and how the multiplicitous nature of the identity of  other  has a particular impact when indigenous, gender and disability are all identified from marginalised groups. I also explore the impact of westernised thinking around impairment, in particular the models of disabilities on indigenous well-being. The issues of family (whānau), whakawhanaungatanga (family relationships), interdependence (community) and collectivity identities central to indigenous thinking are largely ignored by law and policy, yet central to indigenous identity. This ignorance in policy has led to the disparities that continue to remain for indigenous persons with disabilities, particularly those from within thematic identity groups.

year: 2008