title: Prediction Intervals for Class Probabilities

authors: Yu, Xiaofeng

subjects: bayesian classifier

abstract: Prediction intervals for class probabilities are of interest in machine learning because they
can quantify the uncertainty about the class probability estimate for a test instance. The
idea is that all likely class probability values of the test instance are included, with a
pre-specified confidence level, in the calculated prediction interval. This thesis proposes a
probabilistic model for calculating such prediction intervals. Given the unobservability of
class probabilities, a Bayesian approach is employed to derive a complete distribution of the
class probability of a test instance based on a set of class observations of training instances
in the neighbourhood of the test instance. A random decision tree ensemble learning
algorithm is also proposed, whose prediction output constitutes the neighbourhood that
is used by the Bayesian model to produce a PI for the test instance. The Bayesian
model, which is used in conjunction with the ensemble learning algorithm and the standard
nearest-neighbour classifier, is evaluated on artificial datasets and modified real datasets.

text: Prediction Intervals for Class Probabilities Prediction intervals for class probabilities are of interest in machine learning because they
can quantify the uncertainty about the class probability estimate for a test instance. The
idea is that all likely class probability values of the test instance are included, with a
pre-specified confidence level, in the calculated prediction interval. This thesis proposes a
probabilistic model for calculating such prediction intervals. Given the unobservability of
class probabilities, a Bayesian approach is employed to derive a complete distribution of the
class probability of a test instance based on a set of class observations of training instances
in the neighbourhood of the test instance. A random decision tree ensemble learning
algorithm is also proposed, whose prediction output constitutes the neighbourhood that
is used by the Bayesian model to produce a PI for the test instance. The Bayesian
model, which is used in conjunction with the ensemble learning algorithm and the standard
nearest-neighbour classifier, is evaluated on artificial datasets and modified real datasets.

year: 2007

title: Ethical, legal, and social issues in the Earth BioGenome Project.

authors: Sherkow, Jacob S.

subjects: EBP

abstract: The Earth BioGenome Project (EBP) is an audacious endeavor to obtain whole-genome sequences of representatives from all eukaryotic species on Earth. In addition to the project's technical and organizational challenges, it also faces complicated ethical, legal, and social issues. This paper, from members of the EBP's Ethical, Legal, and Social Issues (ELSI) Committee, catalogs these ELSI concerns arising from EBP. These include legal issues, such as sample collection and permitting; the applicability of international treaties, such as the Convention on Biological Diversity and the Nagoya Protocol; intellectual property; sample accessioning; and biosecurity and ethical issues, such as sampling from the territories of Indigenous peoples and local communities, the protection of endangered species, and cross-border collections, among several others. We also comment on the intersection of digital sequence information and data rights. More broadly, this list of ethical, legal, and social issues for large-scale genomic sequencing projects may be useful in the consideration of ethical frameworks for future projects. While we do not-and cannot-provide simple, overarching solutions for all the issues raised here, we conclude our perspective by beginning to chart a path forward for EBP's work.

text: Ethical, legal, and social issues in the Earth BioGenome Project. The Earth BioGenome Project (EBP) is an audacious endeavor to obtain whole-genome sequences of representatives from all eukaryotic species on Earth. In addition to the project's technical and organizational challenges, it also faces complicated ethical, legal, and social issues. This paper, from members of the EBP's Ethical, Legal, and Social Issues (ELSI) Committee, catalogs these ELSI concerns arising from EBP. These include legal issues, such as sample collection and permitting; the applicability of international treaties, such as the Convention on Biological Diversity and the Nagoya Protocol; intellectual property; sample accessioning; and biosecurity and ethical issues, such as sampling from the territories of Indigenous peoples and local communities, the protection of endangered species, and cross-border collections, among several others. We also comment on the intersection of digital sequence information and data rights. More broadly, this list of ethical, legal, and social issues for large-scale genomic sequencing projects may be useful in the consideration of ethical frameworks for future projects. While we do not-and cannot-provide simple, overarching solutions for all the issues raised here, we conclude our perspective by beginning to chart a path forward for EBP's work.

year: 2022

title: Te Tuhirau i Rehu i Ringa: Translating Sacred and Sensitive Texts: An Indigenous Perspective

authors: Tipene, Jillian

subjects: translation

abstract: This thesis centers on translator cognition. Through a series of interviews and think-aloud protocols (Chapters 3 – 5), it explores the ways in which a sample of translators (both Māori and non-Māori) negotiate the complex issues involved in translating between a local, Indigenous language (Māori) and an international one (English) and, in particular, how they approach the definition and translation of texts that could be regarded as being ‘sacred’ and/or ‘sensitive’. In their definitions of ‘sacred’ texts and ‘sensitive’ texts, all of the participants exhibited a peculiarly postmodern positioning, focussing primarily on perspective rather than on any absolute concept of truth or reality. With the exception of the Māori participants’ traditional definition of, and approach to texts deemed to be ‘tapu’ (see Chapter 3), all of the participants expressed beliefs about the translation process which were largely structurally-orientated. They emphasized the importance of respecting the cultural context out of which texts emerged and of attempting, in translation, to reflect the meanings deemed to reside in the source texts by virtue of the intentions of their authors. As witnessed in their think-aloud protocols, however, when involved in the actual process of translation the translators did not always adhere to the views expressed in their interviews, with translation procedures ranging from one that was primarily modernist and structural in orientation (but also reflecting the careful attention to co-text and cohesion that is characteristic of much recent research on discourse analysis) to one that was primarily postmodern and post-structural in orientation, being highly personal, autonomous and individualistic.  

In the absence of any clear agreement about translation theory in the literature on translation (see Chapter 2), and at a time when pre-modern, modern and postmodern positioning and structural and post-structural perspectives vie for acceptance, each of the participants in this research project appears to have found his or her own way of traversing the complex terrain of translation practice without necessarily being fully aware of the way in which the decisions they made positioned them theoretically. What this suggests is the need for a type of training that introduces novice translators in an explicit way to a variety of theories about human language and communication and the ways in which they can impinge upon translation practice, thus creating a context in which translators are able to make critically informed decisions about how they will proceed in any particular instance, why they will proceed in these ways, and what is required in order to ensure that their beliefs about translation are in accord with their actual practices. Critical awareness of these issues is likely to be particularly important in the case of those involved in translating between international languages such as English and more localized, Indigenous languages such as Māori, where discontinuity in the transmission of the language has occurred and where, therefore, texts that are deemed to be of particular significance would otherwise be unavailable to those for whom the texts form part of their cultural heritage.

text: Te Tuhirau i Rehu i Ringa: Translating Sacred and Sensitive Texts: An Indigenous Perspective This thesis centers on translator cognition. Through a series of interviews and think-aloud protocols (Chapters 3 – 5), it explores the ways in which a sample of translators (both Māori and non-Māori) negotiate the complex issues involved in translating between a local, Indigenous language (Māori) and an international one (English) and, in particular, how they approach the definition and translation of texts that could be regarded as being ‘sacred’ and/or ‘sensitive’. In their definitions of ‘sacred’ texts and ‘sensitive’ texts, all of the participants exhibited a peculiarly postmodern positioning, focussing primarily on perspective rather than on any absolute concept of truth or reality. With the exception of the Māori participants’ traditional definition of, and approach to texts deemed to be ‘tapu’ (see Chapter 3), all of the participants expressed beliefs about the translation process which were largely structurally-orientated. They emphasized the importance of respecting the cultural context out of which texts emerged and of attempting, in translation, to reflect the meanings deemed to reside in the source texts by virtue of the intentions of their authors. As witnessed in their think-aloud protocols, however, when involved in the actual process of translation the translators did not always adhere to the views expressed in their interviews, with translation procedures ranging from one that was primarily modernist and structural in orientation (but also reflecting the careful attention to co-text and cohesion that is characteristic of much recent research on discourse analysis) to one that was primarily postmodern and post-structural in orientation, being highly personal, autonomous and individualistic.  

In the absence of any clear agreement about translation theory in the literature on translation (see Chapter 2), and at a time when pre-modern, modern and postmodern positioning and structural and post-structural perspectives vie for acceptance, each of the participants in this research project appears to have found his or her own way of traversing the complex terrain of translation practice without necessarily being fully aware of the way in which the decisions they made positioned them theoretically. What this suggests is the need for a type of training that introduces novice translators in an explicit way to a variety of theories about human language and communication and the ways in which they can impinge upon translation practice, thus creating a context in which translators are able to make critically informed decisions about how they will proceed in any particular instance, why they will proceed in these ways, and what is required in order to ensure that their beliefs about translation are in accord with their actual practices. Critical awareness of these issues is likely to be particularly important in the case of those involved in translating between international languages such as English and more localized, Indigenous languages such as Māori, where discontinuity in the transmission of the language has occurred and where, therefore, texts that are deemed to be of particular significance would otherwise be unavailable to those for whom the texts form part of their cultural heritage.

year: 2014