title: Bayesian sequence learning for predicting protein cleavage points

authors: Mayo, Michael

subjects: computer science

abstract: A challenging problem in data mining is the application of efficient techniques to automatically annotate the vast databases of biological sequence data. This paper describes one such application in this area, to the prediction of the position of signal peptide cleavage points along protein sequences. It is shown that the method, based on Bayesian statistics, is comparable in terms of accuracy to the existing state-of-the-art neural network techniques while providing explanatory information for its predictions.

text: Bayesian sequence learning for predicting protein cleavage points A challenging problem in data mining is the application of efficient techniques to automatically annotate the vast databases of biological sequence data. This paper describes one such application in this area, to the prediction of the position of signal peptide cleavage points along protein sequences. It is shown that the method, based on Bayesian statistics, is comparable in terms of accuracy to the existing state-of-the-art neural network techniques while providing explanatory information for its predictions.

year: 2005

title: Reply to “Comment on ‘Evolution of energy-containing turbulent eddies in the solar wind’ by W. H. Matthaeus, S. Oughton, D. H. Pontius Jr., and Y. Zhou”

authors: Matthaeus, William H.

abstract: In their preceding comment on our paper [Matthaeus et al., 1994] (hereinafter reffered to as paper 1), Tu and Marsh [this issue] object vehemently to what they perceive as undeserved criticism of the class of solar wind turbulence models developed by Tu and coworkers[Tu et al., 1984, Tu, 1987, 1988]. Our intent was not to slight the valuable contributions made in those groundbreaking theories for incorporating turbulence into models for spatial transport. Rather, we wished to point out certain shortcomings in existing theories and suggest how they might be improved.

text: Reply to “Comment on ‘Evolution of energy-containing turbulent eddies in the solar wind’ by W. H. Matthaeus, S. Oughton, D. H. Pontius Jr., and Y. Zhou” In their preceding comment on our paper [Matthaeus et al., 1994] (hereinafter reffered to as paper 1), Tu and Marsh [this issue] object vehemently to what they perceive as undeserved criticism of the class of solar wind turbulence models developed by Tu and coworkers[Tu et al., 1984, Tu, 1987, 1988]. Our intent was not to slight the valuable contributions made in those groundbreaking theories for incorporating turbulence into models for spatial transport. Rather, we wished to point out certain shortcomings in existing theories and suggest how they might be improved.

year: 1995

title: Pakeha students and a pro-Treaty analysis: Teaching issues in a diploma of clinical psychology programme

authors: Yensen, Helen

subjects: Maori

abstract: We ran Treaty/biculturalism workshops for the Diploma on an ad hoc basis in 1990, 1991, and 1992. This year we have contracted for a fuller package which involves work with first and second years and staff. Next year this will continue with third year students. We believe biculturalism training for non-Maori has two major aspects and, although they overlap in various ways we think that it is useful to separate them: the first one is awareness of Maori cultural practices, values, etc, which can perhaps be called ‘cultural sensitivity training’. This needs to be under the control of Maori and have major input from Maori. The second aspect is where our focus is, and that is awareness of the effect on the Maori world of the loss of sovereignty by Maori; of their marginalisation over the last one hundred and fifty years by Pakeha; of their oppressed status; loss of economic base, and the implications for change that flow from those events. We believe that, at least initially, Pakeha have the responsibility for educating themselves and other pakeha in this area.

text: Pakeha students and a pro-Treaty analysis: Teaching issues in a diploma of clinical psychology programme We ran Treaty/biculturalism workshops for the Diploma on an ad hoc basis in 1990, 1991, and 1992. This year we have contracted for a fuller package which involves work with first and second years and staff. Next year this will continue with third year students. We believe biculturalism training for non-Maori has two major aspects and, although they overlap in various ways we think that it is useful to separate them: the first one is awareness of Maori cultural practices, values, etc, which can perhaps be called ‘cultural sensitivity training’. This needs to be under the control of Maori and have major input from Maori. The second aspect is where our focus is, and that is awareness of the effect on the Maori world of the loss of sovereignty by Maori; of their marginalisation over the last one hundred and fifty years by Pakeha; of their oppressed status; loss of economic base, and the implications for change that flow from those events. We believe that, at least initially, Pakeha have the responsibility for educating themselves and other pakeha in this area.

year: 1993