title: Effects of capture stress on free-ranging, reproductively active male Weddell seals

authors: Harcourt, Robert Geoffrey

subjects: marine mammals

abstract: Physiological stress responses to capture may be an indicator of welfare challenges induced by animal handling. Simultaneously, blood chemistry changes induced by stress responses may confound experimental design by interacting with the biological parameters being measured. Cortisol elevation is a common indicator of stress responses in mammals and reproductive condition can profoundly influence endocrine response. We measured changes in blood cortisol and testosterone induced by handling reproductively active male Weddell seals (Leptonychotes weddellii) early and late in the breeding season. Weddell seals have the highest resting cortisol levels of all mammals yet showed a clear, prolonged elevation in cortisol in response to capture. Responses were similar when first caught and when caught a second time, later in the breeding season. Baseline testosterone levels declined over the breeding season but were not altered by capture. Administering a light dose of diazepam significantly ameliorated the cortisol response of handled animals without affecting testosterone levels. This may be an effective way of reducing acute capture stress responses. Male breeding success in years males were handled was no different to the years they were not, despite the acute capture response, suggesting no long-term impact of handling on male reproductive output.

text: Effects of capture stress on free-ranging, reproductively active male Weddell seals Physiological stress responses to capture may be an indicator of welfare challenges induced by animal handling. Simultaneously, blood chemistry changes induced by stress responses may confound experimental design by interacting with the biological parameters being measured. Cortisol elevation is a common indicator of stress responses in mammals and reproductive condition can profoundly influence endocrine response. We measured changes in blood cortisol and testosterone induced by handling reproductively active male Weddell seals (Leptonychotes weddellii) early and late in the breeding season. Weddell seals have the highest resting cortisol levels of all mammals yet showed a clear, prolonged elevation in cortisol in response to capture. Responses were similar when first caught and when caught a second time, later in the breeding season. Baseline testosterone levels declined over the breeding season but were not altered by capture. Administering a light dose of diazepam significantly ameliorated the cortisol response of handled animals without affecting testosterone levels. This may be an effective way of reducing acute capture stress responses. Male breeding success in years males were handled was no different to the years they were not, despite the acute capture response, suggesting no long-term impact of handling on male reproductive output.

year: 2010

title: Rasch analysis of the hospital anxiety and depression scale in patients with chronic fatigue syndrome

authors: Bartholomew, Emerson J.

subjects: Chronic fatigue syndrome

abstract: Background: The Hospital Anxiety and Depression Scale (HADS) is widely utilized for assessing psychological distress in medical populations, yet its clinimetric properties in chronic fatigue conditions remain underexplored. Given the complex symptom presentation in chronic fatigue syndrome (CFS), rigorous clinimetric validation is essential for accurate clinical assessment. 

Objective: This study aimed to evaluate the clinimetric properties of the HADS using Rasch methodology in patients with CFS, with particular emphasis on dimensionality, item functioning, and measurement precision. 

Methods: Rasch analysis was conducted on HADS responses from 286 participants diagnosed with CFS. The Partial Credit Rasch model was applied to assess overall model fit, item performance, unidimensionality and differential item functioning. 

Results: Initial analysis revealed suboptimal model fit, necessitating subtest modifications to address local response dependence. The subtest solution demonstrated acceptable fit to the Rasch model with evidence of strict unidimensionality, high reliability (PSI = 0.87), and no differential item functioning by demographic variables. Rasch-converted interval scores showed improved measurement precision compared to ordinal scoring. Interval scoring yielding a significantly higher mean (M = 22.55, SD = 3.78) compared to unconverted scoring (M = 20.30, SD = 6.87), t(275) = −19.54, p < .001, indicating that ordinal scoring systematically underestimates the latent trait level. Interval scores showed a 45 % reduction in measurement error demonstrated by the substantial reduction in standard error. 

Conclusions: The HADS demonstrated acceptable measurement properties in patients with CFS. The development of ordinal-to-interval conversion tables enhances the scale's precision, supporting its continued use in clinical and research contexts.

text: Rasch analysis of the hospital anxiety and depression scale in patients with chronic fatigue syndrome Background: The Hospital Anxiety and Depression Scale (HADS) is widely utilized for assessing psychological distress in medical populations, yet its clinimetric properties in chronic fatigue conditions remain underexplored. Given the complex symptom presentation in chronic fatigue syndrome (CFS), rigorous clinimetric validation is essential for accurate clinical assessment. 

Objective: This study aimed to evaluate the clinimetric properties of the HADS using Rasch methodology in patients with CFS, with particular emphasis on dimensionality, item functioning, and measurement precision. 

Methods: Rasch analysis was conducted on HADS responses from 286 participants diagnosed with CFS. The Partial Credit Rasch model was applied to assess overall model fit, item performance, unidimensionality and differential item functioning. 

Results: Initial analysis revealed suboptimal model fit, necessitating subtest modifications to address local response dependence. The subtest solution demonstrated acceptable fit to the Rasch model with evidence of strict unidimensionality, high reliability (PSI = 0.87), and no differential item functioning by demographic variables. Rasch-converted interval scores showed improved measurement precision compared to ordinal scoring. Interval scoring yielding a significantly higher mean (M = 22.55, SD = 3.78) compared to unconverted scoring (M = 20.30, SD = 6.87), t(275) = −19.54, p < .001, indicating that ordinal scoring systematically underestimates the latent trait level. Interval scores showed a 45 % reduction in measurement error demonstrated by the substantial reduction in standard error. 

Conclusions: The HADS demonstrated acceptable measurement properties in patients with CFS. The development of ordinal-to-interval conversion tables enhances the scale's precision, supporting its continued use in clinical and research contexts.

year: 2025

title: Ue Waerea

authors: Tuaupiki, Jackie Whetumarama

subjects: Waerea

abstract: Mai i Mōkau ki Tāmaki, Mangatoatoa, Pare-Waikato, Pare-Hauraki, Te Kaokaoroa o Pātetere, ko te whakapono, nā Tāwhaki i piki te poutama ki te tāhuhu matapu, ka riro mai i a ia ngā kete o te wānanga. E kīngia ai, ko te pūtake tērā o te mātauranga Māori. Hei tā Wiri (2001), nā te mātauranga Māori, ko te mātauranga Māori ā-waha. Nāna, ko te waiata. Nā te waiata, ko te karakia. Kei raro i te karakia, ko te takere kaupapa tēnei, ko te waerea. Ko te whāinga o tēnei tuhituhinga, he rangahau i ngā pūtake o te waerea me te āta titiro ki ngā kaupapa kei a ia me tōna kawe i roto i aua kaupapa i ngā wā o mua, ā, nō nāianei hoki. Ko te waerea te pane o ngā karakia Māori ki roto o Tainui, otirā, ki roto i ngētehi o ngā whakaritenga, ā, ka tirohia ngēnei whakaritenga e rere ai te waerea, pēnei i te tomo whare, i te tomo urupā, i te takahi whare, i te whakamānu waka me te maha o ngā mahi a te ao Māori ki roto o Tainui.

text: Ue Waerea Mai i Mōkau ki Tāmaki, Mangatoatoa, Pare-Waikato, Pare-Hauraki, Te Kaokaoroa o Pātetere, ko te whakapono, nā Tāwhaki i piki te poutama ki te tāhuhu matapu, ka riro mai i a ia ngā kete o te wānanga. E kīngia ai, ko te pūtake tērā o te mātauranga Māori. Hei tā Wiri (2001), nā te mātauranga Māori, ko te mātauranga Māori ā-waha. Nāna, ko te waiata. Nā te waiata, ko te karakia. Kei raro i te karakia, ko te takere kaupapa tēnei, ko te waerea. Ko te whāinga o tēnei tuhituhinga, he rangahau i ngā pūtake o te waerea me te āta titiro ki ngā kaupapa kei a ia me tōna kawe i roto i aua kaupapa i ngā wā o mua, ā, nō nāianei hoki. Ko te waerea te pane o ngā karakia Māori ki roto o Tainui, otirā, ki roto i ngētehi o ngā whakaritenga, ā, ka tirohia ngēnei whakaritenga e rere ai te waerea, pēnei i te tomo whare, i te tomo urupā, i te takahi whare, i te whakamānu waka me te maha o ngā mahi a te ao Māori ki roto o Tainui.

year: 2011-04