title: Steroidal Glycosides of Cordyline australis

authors: Korkashvili, Tamar

subjects: cordyline australis

abstract: The n-butanol extract of aerial parts of Cordyline australis demonstrated antifungal activity. n-Butanol and chloroform extracts of dried or fresh leaves of C. australis afforded a steroidal glycoside, which was identified as 5α-spirost-25(27)-en-3β-ol 3-O{O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside}, saponin 1. This spirostanol glycoside showed strong antifungal activity towards Trichophyton mentagrophytes and some aspecific activity and cytotoxicity against MRC5 cell.
The chloroform extract of fresh leaves of C. australis yielded a second new spirostanol glycoside which was identified as 5α-spirost-25(27)-ene-1β,3β-diol 1-{O-α-L-rhamnopyranosyl-(1→2)-β-D-fucopyranoside}, saponin 2. The n-butanol extracts of senescent leaves of C. australis afforded a third new spirostanol glycoside that was identified as 5α-spirost-25(27)-ene-1β,3β-diol 1-{O-β-D- fucopyranoside, saponin 3.
A mixture of two isomeric flavonoid glycosides was isolated from dried leaves of C. australis and shown to be a ca 1:1 mixture of isorhamnetin-3-O-{O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside}, 4 and isorhamnetin-3-O-{O-α-L-rhamnopyranosyl-(1→6)-β-D-galactopyranoside}, 5.
Three other known steroidal glycosides, β-sitosterol glucoside, 6, prosapogenin A of dioscin, 7, and trillin, 8 were also isolated from the leaves of C. australis. The n-butanol extract of dried stems of C. australis afforded (25S)-5α-spirostane-1β,3α-diol 1-{O-β-D-glucopyranoside}, 9. This spirostanol glycoside showed moderate cytotoxicity against Herpes simplex type I virus (ATCC VR733) and Polio Virus Type I (Pfiser vaccine strain).

text: Steroidal Glycosides of Cordyline australis The n-butanol extract of aerial parts of Cordyline australis demonstrated antifungal activity. n-Butanol and chloroform extracts of dried or fresh leaves of C. australis afforded a steroidal glycoside, which was identified as 5α-spirost-25(27)-en-3β-ol 3-O{O-α-L-rhamnopyranosyl-(1→2)-β-D-glucopyranoside}, saponin 1. This spirostanol glycoside showed strong antifungal activity towards Trichophyton mentagrophytes and some aspecific activity and cytotoxicity against MRC5 cell.
The chloroform extract of fresh leaves of C. australis yielded a second new spirostanol glycoside which was identified as 5α-spirost-25(27)-ene-1β,3β-diol 1-{O-α-L-rhamnopyranosyl-(1→2)-β-D-fucopyranoside}, saponin 2. The n-butanol extracts of senescent leaves of C. australis afforded a third new spirostanol glycoside that was identified as 5α-spirost-25(27)-ene-1β,3β-diol 1-{O-β-D- fucopyranoside, saponin 3.
A mixture of two isomeric flavonoid glycosides was isolated from dried leaves of C. australis and shown to be a ca 1:1 mixture of isorhamnetin-3-O-{O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside}, 4 and isorhamnetin-3-O-{O-α-L-rhamnopyranosyl-(1→6)-β-D-galactopyranoside}, 5.
Three other known steroidal glycosides, β-sitosterol glucoside, 6, prosapogenin A of dioscin, 7, and trillin, 8 were also isolated from the leaves of C. australis. The n-butanol extract of dried stems of C. australis afforded (25S)-5α-spirostane-1β,3α-diol 1-{O-β-D-glucopyranoside}, 9. This spirostanol glycoside showed moderate cytotoxicity against Herpes simplex type I virus (ATCC VR733) and Polio Virus Type I (Pfiser vaccine strain).

year: 2006

title: National standards for New Zealand’s primary and intermediate school pupils

authors: Thrupp, Martin

subjects: New Zealand

abstract: A key education policy plank for the National Party going into the 2008 election is to be National Standards for primary and intermediate pupils in reading, writing and numeracy. These are seen to be more acceptable than the national testing which occurs in England, the United States and other countries. But are they really more acceptable? This article will review evidence about the perverse effects of national testing, consider what is known about the National Standards proposed for New Zealand, and assess whether they are likely to avid many of the same damaging effect on schools and pupils. It is argued that although the National Party is trying to distinguish its policies from national testing, the distinctions are not yet significant enough to prevent the problems which have been experienced overseas.

text: National standards for New Zealand’s primary and intermediate school pupils A key education policy plank for the National Party going into the 2008 election is to be National Standards for primary and intermediate pupils in reading, writing and numeracy. These are seen to be more acceptable than the national testing which occurs in England, the United States and other countries. But are they really more acceptable? This article will review evidence about the perverse effects of national testing, consider what is known about the National Standards proposed for New Zealand, and assess whether they are likely to avid many of the same damaging effect on schools and pupils. It is argued that although the National Party is trying to distinguish its policies from national testing, the distinctions are not yet significant enough to prevent the problems which have been experienced overseas.

year: 2007

title: Moving away from home: Some social consequences for Tūhoe migrating to the Waikato

authors: Nikora, Linda Waimarie

subjects: psychology

abstract: To better understand the social consequences of migration away from traditional iwi regions, Tūhoe researchers intensively interviewed 40 Tūhoe people who had moved to the Waikato. It was found that most missed whanau and the community and made regular visits back home. Participants reported utilizing extensive whanau links to set themselves up in the Waikato, and many joined the Tūhoe associations in the Waikato. Others who did not join reported liking the idea that Tūhoe were there if needed. Some participants felt stronger in their Tūhoe identity since moving, and most reported noticing changes occurring in themselves or those back home over this period (they felt more worldly but saw those back home as more insular). While they did not interact much with tangata whenua, or participate in tangata whenua events, many said that they had a better appreciation of the local Tainui and the Kīngitanga groups since migrating. Finally, most would like to return to their iwi region for employment if it were available but saw little chance of this happening, and most reported wanting to retire there. The policy implications of both these points are explored.

text: Moving away from home: Some social consequences for Tūhoe migrating to the Waikato To better understand the social consequences of migration away from traditional iwi regions, Tūhoe researchers intensively interviewed 40 Tūhoe people who had moved to the Waikato. It was found that most missed whanau and the community and made regular visits back home. Participants reported utilizing extensive whanau links to set themselves up in the Waikato, and many joined the Tūhoe associations in the Waikato. Others who did not join reported liking the idea that Tūhoe were there if needed. Some participants felt stronger in their Tūhoe identity since moving, and most reported noticing changes occurring in themselves or those back home over this period (they felt more worldly but saw those back home as more insular). While they did not interact much with tangata whenua, or participate in tangata whenua events, many said that they had a better appreciation of the local Tainui and the Kīngitanga groups since migrating. Finally, most would like to return to their iwi region for employment if it were available but saw little chance of this happening, and most reported wanting to retire there. The policy implications of both these points are explored.

year: 2004