title: Superantigen architecture: Functional decoration on a conserved scaffold

authors: Arcus, Vickery L.

subjects: biology

abstract: A defining and consistent feature of the bacterial superantigens from Staphylococcus aureus and Streptococcus pyogenes is their strongly conserved three-dimensional structure. Structural studies to date show that the array of more than 280 amino acid sequences known for superantigens (SAgs) and staphylococcal superantigen-like (SSL) proteins all have the same fold-a structure in which the same three-dimensional arrangement of α-helices and β-sheets is traced by each amino acid sequence, with the same topology (for recent reviews, see references 29 and 43). A typical SAg structure comprises two domains-an N-terminal β -barrel domain called an OB-fold (4, 25) and a C-terminal β-grasp domain in which a long α-helix packs on to a mixed parallel and antiparallel β-sheet. These two domains are traversed by an α-helix that lies at the N terminus of the protein and packs against the β-grasp domain, thus linking the N- and C-terminal domains.

text: Superantigen architecture: Functional decoration on a conserved scaffold A defining and consistent feature of the bacterial superantigens from Staphylococcus aureus and Streptococcus pyogenes is their strongly conserved three-dimensional structure. Structural studies to date show that the array of more than 280 amino acid sequences known for superantigens (SAgs) and staphylococcal superantigen-like (SSL) proteins all have the same fold-a structure in which the same three-dimensional arrangement of α-helices and β-sheets is traced by each amino acid sequence, with the same topology (for recent reviews, see references 29 and 43). A typical SAg structure comprises two domains-an N-terminal β -barrel domain called an OB-fold (4, 25) and a C-terminal β-grasp domain in which a long α-helix packs on to a mixed parallel and antiparallel β-sheet. These two domains are traversed by an α-helix that lies at the N terminus of the protein and packs against the β-grasp domain, thus linking the N- and C-terminal domains.

year: 2007

title: Towards the design of a kid’s music organizer

authors: Cunningham, Sally Jo

subjects: computer science

abstract: In this paper, we investigate how young children aged 2 to 5 interact with music and their family's music collections. By going into their homes, interviewing them and their parents and observing the children performing a range of music-related tasks, we explore the way that pre-school children select, interact with, and organize music. Additionally, drawing tasks were included in the visits to engage the children and allow them to demonstrate their thoughts in a concrete manner. Insights into the children's' music behaviours suggest design features for a music organizer / player for very young children.

text: Towards the design of a kid’s music organizer In this paper, we investigate how young children aged 2 to 5 interact with music and their family's music collections. By going into their homes, interviewing them and their parents and observing the children performing a range of music-related tasks, we explore the way that pre-school children select, interact with, and organize music. Additionally, drawing tasks were included in the visits to engage the children and allow them to demonstrate their thoughts in a concrete manner. Insights into the children's' music behaviours suggest design features for a music organizer / player for very young children.

year: 2008

title: Te Pai Tawhiti: Exploring the Horizons of Maori Economic Performance through Effective Collaboration

authors: Joseph, Robert

abstract: Effective collaboration, good governance and active management provide a potential platform for enhanced economic performance for Ngāti Pikiao, in line with its self-determination aspirations to
work better as a collective of entities on behalf of iwi members.

Literature and case study data analyses show a pathway forward for Ngāti Pikiao in the form of 9 key principles for working towards a foundation for effective collaborative action that enhances economic
performance.

text: Te Pai Tawhiti: Exploring the Horizons of Maori Economic Performance through Effective Collaboration Effective collaboration, good governance and active management provide a potential platform for enhanced economic performance for Ngāti Pikiao, in line with its self-determination aspirations to
work better as a collective of entities on behalf of iwi members.

Literature and case study data analyses show a pathway forward for Ngāti Pikiao in the form of 9 key principles for working towards a foundation for effective collaborative action that enhances economic
performance.

year: 2016