title: Isolation and structure elucidation of secopenitrem D, an indole alkaloid from Penicillium crustosum Thom

authors: Moldes-Anaya, Angel

subjects: secopenitrem D

abstract: Chemical investigation of three isolates of Penicillium crustosum Thom cultures, one of which was derived from a recent dog poisoning investigation, has led to the isolation and structure elucidation of secopenitrem D (1). Penitrems A-F and roquefortine C were also present in the isolates analyzed. The structure of 1 was unambiguously assigned based on extensive 1D- and 2D-NMR spectroscopic experiments, MS-aided structural studies and by comparison with structurally related congeners. Secopenitrem D lacks the C-16−C-18 ether linkage present in penitrems A-F.

text: Isolation and structure elucidation of secopenitrem D, an indole alkaloid from Penicillium crustosum Thom Chemical investigation of three isolates of Penicillium crustosum Thom cultures, one of which was derived from a recent dog poisoning investigation, has led to the isolation and structure elucidation of secopenitrem D (1). Penitrems A-F and roquefortine C were also present in the isolates analyzed. The structure of 1 was unambiguously assigned based on extensive 1D- and 2D-NMR spectroscopic experiments, MS-aided structural studies and by comparison with structurally related congeners. Secopenitrem D lacks the C-16−C-18 ether linkage present in penitrems A-F.

year: 2010

title: Radiocarbon age of the Kaharoa Tephra, a key marker for late-Holocene stratigraphy and archaeology in New Zealand

authors: Lowe, David J.

subjects: radiocarbon dating

abstract: The Kaharoa eruption, the most recent rhyolitic volcanic event in New Zealand, resulted in the deposition of the compositionally distinctive Kaharoa Tephra over at least 30 000 km2 of northern and eastern North Island. The tephra forms an isochronous marker bed for various late-Holocene stratigraphic and palaeoen vironmental studies but is particularly important for evaluating the chronology of New Zealand's notably short prehistory because it was erupted within the last millennium, close to the time of first Polynesian colonization. We derive a definitive radiocarbon age, previously ambiguous, for the Kaharoa Tephra of 665615 BP using cluster analysis of 22 radiocarbon ages relevant to the Kaharoa eruptive episode. The error-weighted mean age obtained on unscreened ages, minus outliers, is supported by statistically identical ages obtained from three sets of screened ages selected to minimize the effects of inbuilt age or contamination. Based on the intercepts method and 1 sigma range of Northern Hemisphere calibration curves, and after subtraction of 27 years for the interhemispheric offset, the radiocarbon age 665615 BP corresponds to calibrated dates ranging from c. 650–560 cal. BP (i.e. cal. ad 1300–1390). The approximate midpoint of this range provides a colloquial calen dar date for the Kaharoa Tephra of c. 600 cal. BP (c. cal. ad 1350).

text: Radiocarbon age of the Kaharoa Tephra, a key marker for late-Holocene stratigraphy and archaeology in New Zealand The Kaharoa eruption, the most recent rhyolitic volcanic event in New Zealand, resulted in the deposition of the compositionally distinctive Kaharoa Tephra over at least 30 000 km2 of northern and eastern North Island. The tephra forms an isochronous marker bed for various late-Holocene stratigraphic and palaeoen vironmental studies but is particularly important for evaluating the chronology of New Zealand's notably short prehistory because it was erupted within the last millennium, close to the time of first Polynesian colonization. We derive a definitive radiocarbon age, previously ambiguous, for the Kaharoa Tephra of 665615 BP using cluster analysis of 22 radiocarbon ages relevant to the Kaharoa eruptive episode. The error-weighted mean age obtained on unscreened ages, minus outliers, is supported by statistically identical ages obtained from three sets of screened ages selected to minimize the effects of inbuilt age or contamination. Based on the intercepts method and 1 sigma range of Northern Hemisphere calibration curves, and after subtraction of 27 years for the interhemispheric offset, the radiocarbon age 665615 BP corresponds to calibrated dates ranging from c. 650–560 cal. BP (i.e. cal. ad 1300–1390). The approximate midpoint of this range provides a colloquial calen dar date for the Kaharoa Tephra of c. 600 cal. BP (c. cal. ad 1350).

year: 1998

title: PIWeCS: enhancing human/machine agency in an interactive composition system

authors: Whalley, Ian

abstract: This paper focuses on the infrastructure and aesthetic approach used in PIWeCS: a Public Space Interactive Web-based Composition System. The concern was to increase the sense of dialogue between human and machine agency in an interactive work by adapting Paine's (2002) notion of a conversational model of interaction as a ‘complex system’. The machine implementation of PIWeCS is achieved through integrating intelligent agent programming with MAX/MSP. Human input is through a web infrastructure. The conversation is initiated and continued by participants through arrangements and composition based on short performed samples of traditional New Zealand Maori instruments. The system allows the extension of a composition through the electroacoustic manipulation of the source material.

text: PIWeCS: enhancing human/machine agency in an interactive composition system This paper focuses on the infrastructure and aesthetic approach used in PIWeCS: a Public Space Interactive Web-based Composition System. The concern was to increase the sense of dialogue between human and machine agency in an interactive work by adapting Paine's (2002) notion of a conversational model of interaction as a ‘complex system’. The machine implementation of PIWeCS is achieved through integrating intelligent agent programming with MAX/MSP. Human input is through a web infrastructure. The conversation is initiated and continued by participants through arrangements and composition based on short performed samples of traditional New Zealand Maori instruments. The system allows the extension of a composition through the electroacoustic manipulation of the source material.

year: 2004