title: Overtraining and the complexities of coaches’ decision making: Managing elite athletes on the training cusp.

authors: Pope, Clive C.

subjects: overtraining

abstract: In many elite sport performance contexts overtraining is a critical issue for coaches to understand, recognise and respond to. While the indicators and effects of overtraining have attracted considerable research interest, there are no diagnostic tests that reliably predict impending overtraining. This study explored the practices and beliefs of three highly successful professional elite rowing coaches as they predicted and managed the risk of athlete overtraining during crucial periods of intensive training. These coaches took part in a series of semi-structured interviews that explored their practices, philosophies and experiences. The research draws on sociological perspectives pertinent to coaching pedagogy and more specifically, the tenets of naturalistic decision making in exploring how the coaches define and make decisions about overtraining. In doing so it recognizes that coaching involves decision-making in complex and demanding situations. The coaches were found to monitor the fatigue of their rowers through observation, communication and measures of training pace. In general, the intuitions and cues that were used by coaches had little in common with overtraining markers or indicators that are promoted in the sport science literature. Coaches’ decision-making was based largely on subjective information and processes that were influenced by a range of stressors unique to their positions. We contend that the research provides an important new perspective on coaches’ definitions and management of overtraining and enables management of overtraining to be better understood as a key element of coaching pedagogy in elite performance settings. In this article we argue successful coaches have unique insights into this topical area and this is worthy of future exploration.

text: Overtraining and the complexities of coaches’ decision making: Managing elite athletes on the training cusp. In many elite sport performance contexts overtraining is a critical issue for coaches to understand, recognise and respond to. While the indicators and effects of overtraining have attracted considerable research interest, there are no diagnostic tests that reliably predict impending overtraining. This study explored the practices and beliefs of three highly successful professional elite rowing coaches as they predicted and managed the risk of athlete overtraining during crucial periods of intensive training. These coaches took part in a series of semi-structured interviews that explored their practices, philosophies and experiences. The research draws on sociological perspectives pertinent to coaching pedagogy and more specifically, the tenets of naturalistic decision making in exploring how the coaches define and make decisions about overtraining. In doing so it recognizes that coaching involves decision-making in complex and demanding situations. The coaches were found to monitor the fatigue of their rowers through observation, communication and measures of training pace. In general, the intuitions and cues that were used by coaches had little in common with overtraining markers or indicators that are promoted in the sport science literature. Coaches’ decision-making was based largely on subjective information and processes that were influenced by a range of stressors unique to their positions. We contend that the research provides an important new perspective on coaches’ definitions and management of overtraining and enables management of overtraining to be better understood as a key element of coaching pedagogy in elite performance settings. In this article we argue successful coaches have unique insights into this topical area and this is worthy of future exploration.

year: 2017

title: Managing rising residual flood risk: A national survey of Aotearoa-New Zealand

authors: Fu, Xinyu

abstract: Flooding is one of the most frequent and costliest natural hazards around the world. Traditionally, flood risk management has relied on building protective structures such as levees and dams to protect assets based on historical data (e.g., 1% AEP flood), which encourages development on floodplains, provides a potentially false sense of security to communities, particularly in the context of climate change, and increases residual flood risk (the risk remaining after implementing risk reduction measures). This article aims to contribute to the management of residual risk by drawing on empirical findings from a survey carried out with flood risk practitioners from the public and private sector in Aotearoa New Zealand. Findings indicate fundamental concerns relating to how to best manage residual flood risk, despite its long profile and integration in current policy and practice. Other issues revolve around the use of outdated information to guide decisions and the lack of regulatory power to restrict developments in flood-prone areas protected by hard defense structures. Identified barriers to improving current practice include the lack of national guidance and support, financial resources, public awareness, and some technical constraints such as uncertainties in flood modeling, staff expertise, and data availability.

text: Managing rising residual flood risk: A national survey of Aotearoa-New Zealand Flooding is one of the most frequent and costliest natural hazards around the world. Traditionally, flood risk management has relied on building protective structures such as levees and dams to protect assets based on historical data (e.g., 1% AEP flood), which encourages development on floodplains, provides a potentially false sense of security to communities, particularly in the context of climate change, and increases residual flood risk (the risk remaining after implementing risk reduction measures). This article aims to contribute to the management of residual risk by drawing on empirical findings from a survey carried out with flood risk practitioners from the public and private sector in Aotearoa New Zealand. Findings indicate fundamental concerns relating to how to best manage residual flood risk, despite its long profile and integration in current policy and practice. Other issues revolve around the use of outdated information to guide decisions and the lack of regulatory power to restrict developments in flood-prone areas protected by hard defense structures. Identified barriers to improving current practice include the lack of national guidance and support, financial resources, public awareness, and some technical constraints such as uncertainties in flood modeling, staff expertise, and data availability.

year: 2023-01-01

title: Investigation of in vitro diabetic inflammation and  treatment with Piper excelsum tea extract

authors: Harvey, Savannah

subjects: Piper excelsum

abstract: Induction of inflammation through hyperglycaemia and adiposity has been shown to contribute to the pathogenicity of type 2 diabetes (T2D). The pro-inflammatory cytokine, tumour necrosis factor α (TNF-α) was the first cytokine found to bridge the connection between the immune system and T2D. This was found due to its increased production in the disease state. TNF-α has specifically been linked to the onset of insulin resistance in T2D models. Evidence has shown that heat shock protein 60 (HSP60) may also play a role as a danger signal for the immune system as it can result in the induction of inflammation. Currently, there are no pharmaceutical options for T2D patients which target inflammation. Tea made from the leaves of kawakawa (Piper excelsum) has been used for many generations by Māori as a traditional rākau rongoā (traditional medicine) to treat a range of ailments including inflammation. The aim of this project was to investigate the modulation of inflammation using a commercially available kawakawa tea in human cancer cells in vitro. 

This project involved measuring the growth rate, cytotoxicity, TNF-α production and HSP60 expression upon exposure to three treatments: high glucose, lipopolysaccharide (LPS) or kawakawa tea extract (KTE).

This study showed that a high concentration of KTE (1000 µg/mL) inhibited cell growth in both HEPG2 and HeLa cell lines. Cells treated with this concentration also showed typical morphological signs of apoptosis. Cytotoxicity testing confirmed that there was a significant (p <0.05) decrease in mitochondrial dehydrogenase activity for this treatment which confirmed the cells were likely dying through apoptosis. Over a course of 24-hours three LPS treatments were found to be cytotoxic. These were the 10 ng/mL, 10 µg/mL, and 100 µg/mL concentrations of LPS. After 48-hours all treatments apart from 100 µg/mL KTE treatment were also found to be cytotoxic. The cytotoxicity for these treatments was either due to a reduction in mitochondrial dehydrogenase activity (infers mitochondrial stress) or increased lactate dehydrogenase (LDH) release from cells (infers necrotic cell death). These cytotoxicity experiments allowed for identification of which concentrations should be selected or removed for future experiments. 

Cytotoxicity levels were taken into consideration and experiments were run investigating the induction of TNF-α using enzyme-linked immunosorbent assays (ELISA). Issues regarding negative readings from samples arose which resulted in protocol changes and extensive trouble shooting. It was found that extended exposure times were required to attenuate a positive result from the positive control, LPS. 

HSP60 expression was also measured for human cells exposed to high glucose and KTE treatments. No change in HSP60 expression was detected. However, 24-hour LPS exposure resulted in a significant increase in HSP60 expression compared to the control for the 100 ng/mL LPS treatment. Two concentrations were investigated; 100 ng/mL LPS and 100 µg/mL LPS which resulted in 1.4- and 2.1-fold increases compared to the control, respectively.

Overall, no conclusion could be drawn regarding the modulation of inflammation by KTE. However, this study was able to identify the effect the tea has on human cancer cell growth and the nature of cytotoxicity the tea poses to the cells. It is recommended to continue this research exploring different kawakawa tea blends and using alternative in vitro cell lines and whole animal models.

text: Investigation of in vitro diabetic inflammation and  treatment with Piper excelsum tea extract Induction of inflammation through hyperglycaemia and adiposity has been shown to contribute to the pathogenicity of type 2 diabetes (T2D). The pro-inflammatory cytokine, tumour necrosis factor α (TNF-α) was the first cytokine found to bridge the connection between the immune system and T2D. This was found due to its increased production in the disease state. TNF-α has specifically been linked to the onset of insulin resistance in T2D models. Evidence has shown that heat shock protein 60 (HSP60) may also play a role as a danger signal for the immune system as it can result in the induction of inflammation. Currently, there are no pharmaceutical options for T2D patients which target inflammation. Tea made from the leaves of kawakawa (Piper excelsum) has been used for many generations by Māori as a traditional rākau rongoā (traditional medicine) to treat a range of ailments including inflammation. The aim of this project was to investigate the modulation of inflammation using a commercially available kawakawa tea in human cancer cells in vitro. 

This project involved measuring the growth rate, cytotoxicity, TNF-α production and HSP60 expression upon exposure to three treatments: high glucose, lipopolysaccharide (LPS) or kawakawa tea extract (KTE).

This study showed that a high concentration of KTE (1000 µg/mL) inhibited cell growth in both HEPG2 and HeLa cell lines. Cells treated with this concentration also showed typical morphological signs of apoptosis. Cytotoxicity testing confirmed that there was a significant (p <0.05) decrease in mitochondrial dehydrogenase activity for this treatment which confirmed the cells were likely dying through apoptosis. Over a course of 24-hours three LPS treatments were found to be cytotoxic. These were the 10 ng/mL, 10 µg/mL, and 100 µg/mL concentrations of LPS. After 48-hours all treatments apart from 100 µg/mL KTE treatment were also found to be cytotoxic. The cytotoxicity for these treatments was either due to a reduction in mitochondrial dehydrogenase activity (infers mitochondrial stress) or increased lactate dehydrogenase (LDH) release from cells (infers necrotic cell death). These cytotoxicity experiments allowed for identification of which concentrations should be selected or removed for future experiments. 

Cytotoxicity levels were taken into consideration and experiments were run investigating the induction of TNF-α using enzyme-linked immunosorbent assays (ELISA). Issues regarding negative readings from samples arose which resulted in protocol changes and extensive trouble shooting. It was found that extended exposure times were required to attenuate a positive result from the positive control, LPS. 

HSP60 expression was also measured for human cells exposed to high glucose and KTE treatments. No change in HSP60 expression was detected. However, 24-hour LPS exposure resulted in a significant increase in HSP60 expression compared to the control for the 100 ng/mL LPS treatment. Two concentrations were investigated; 100 ng/mL LPS and 100 µg/mL LPS which resulted in 1.4- and 2.1-fold increases compared to the control, respectively.

Overall, no conclusion could be drawn regarding the modulation of inflammation by KTE. However, this study was able to identify the effect the tea has on human cancer cell growth and the nature of cytotoxicity the tea poses to the cells. It is recommended to continue this research exploring different kawakawa tea blends and using alternative in vitro cell lines and whole animal models.

year: 2021