title: Melt-extruded polyethylene oxide (PEO) rods as drug delivery vehicles: Formulation, performance as controlled release devices and the influence of co-extruded excipients on drug release profiles

authors: Mucalo, Michael R.

abstract: The utility of controlled release medication formulations lies in their ability to keep drugs at steady levels in the blood plasma of recipients and within the termini of the maximum and minimum effective therapeutic levels. This avoids the “ups” and “downs” of medication levels within the body which would have been the result had conventional immediate release tablets been administered instead. In the veterinary field, controlled release medications are essential¹ because of the logistical difficulties of administering drugs on a regular (e.g., daily) basis to animals. The chief advantages of controlled release veterinary medications lie in the ease with which they can be administered; decrease in stress for animals, owing to less need for rounding up and frequent dosing; and, most importantly for farmers, the reduced cost of treatment relative to that for a multiple dosage regime.

text: Melt-extruded polyethylene oxide (PEO) rods as drug delivery vehicles: Formulation, performance as controlled release devices and the influence of co-extruded excipients on drug release profiles The utility of controlled release medication formulations lies in their ability to keep drugs at steady levels in the blood plasma of recipients and within the termini of the maximum and minimum effective therapeutic levels. This avoids the “ups” and “downs” of medication levels within the body which would have been the result had conventional immediate release tablets been administered instead. In the veterinary field, controlled release medications are essential¹ because of the logistical difficulties of administering drugs on a regular (e.g., daily) basis to animals. The chief advantages of controlled release veterinary medications lie in the ease with which they can be administered; decrease in stress for animals, owing to less need for rounding up and frequent dosing; and, most importantly for farmers, the reduced cost of treatment relative to that for a multiple dosage regime.

year: 2012

title: Quality in Measurement: Beyond the deployment barrier

authors: McGregor, Anthony James

subjects: network measurement

abstract: Network measurement stands at an intersection in the development of the science. We explore possible futures for the area and propose some guidelines for the development of stronger measurement techniques. The paper concludes with a discussion of the work of the NLANR and WAND network measurement groups including the NLANR Network Analysis Infrastructure, AMP, PMA, analysis of Voice over IP traffic and separation of HTTP delays into queuing delay, network latency and server delay.

text: Quality in Measurement: Beyond the deployment barrier Network measurement stands at an intersection in the development of the science. We explore possible futures for the area and propose some guidelines for the development of stronger measurement techniques. The paper concludes with a discussion of the work of the NLANR and WAND network measurement groups including the NLANR Network Analysis Infrastructure, AMP, PMA, analysis of Voice over IP traffic and separation of HTTP delays into queuing delay, network latency and server delay.

year: 2002-02

title: Approaching Māori language through meaning: The predominance of Indo-European models of relationships within propositions

authors: Whaanga, Hēmi

subjects: Te reo Māori

abstract: In every language, there are relationships between predicators (such as, for example, 'go'/'haere') and arguments (such as, for example, ‘James'/'Hēmi’). One such relationship that has been proposed is that of agency. Thus, in 'James goes'/ ‘E haere ana a Hēmi’), 'James'/'Hēmi' can be said to be the agent of the action 'go'/'haere'. Much of the international literature on relationships of this type is based on research on English and it has been claimed that the relationships that have been identified are universals. However, there may be differences among languages, differences that are attributable to the fact that different languages encode different ways of perceiving divisions in perceptual space. My aim here is to demonstrate, with reference to a number of different models of predicator/ argument relations, that most of them are based on assumptions that derive from the structure of Indo-European languages, English in particular. In Part 2 of this paper (to appear in a subsequent issue of this Journal), the implications of this discussion will be examined with reference to an analysis of Māori in terms of relationships within propositions.

text: Approaching Māori language through meaning: The predominance of Indo-European models of relationships within propositions In every language, there are relationships between predicators (such as, for example, 'go'/'haere') and arguments (such as, for example, ‘James'/'Hēmi’). One such relationship that has been proposed is that of agency. Thus, in 'James goes'/ ‘E haere ana a Hēmi’), 'James'/'Hēmi' can be said to be the agent of the action 'go'/'haere'. Much of the international literature on relationships of this type is based on research on English and it has been claimed that the relationships that have been identified are universals. However, there may be differences among languages, differences that are attributable to the fact that different languages encode different ways of perceiving divisions in perceptual space. My aim here is to demonstrate, with reference to a number of different models of predicator/ argument relations, that most of them are based on assumptions that derive from the structure of Indo-European languages, English in particular. In Part 2 of this paper (to appear in a subsequent issue of this Journal), the implications of this discussion will be examined with reference to an analysis of Māori in terms of relationships within propositions.

year: 2001-09