title: Synthesis, characterisation, supramolecular aggregation and biological activity of phosphine gold(I) complexes with monoanionic thiourea ligands

authors: Henderson, William

subjects: gold

abstract: A series of phosphine gold(I) complexes containing monoanionic thiourea ligands has been synthesised by reaction of the appropriate precursor chloro complex, Ph₃PAuCl, Cy₃PAuCl, dppf(AuCl)₂ [dppf = Fe(η⁵-C₅H₄PPh₂)₂] or dppe(AuCl)₂ (dppe = Ph₂PCH₂CH₂PPh₂) with the thiourea and Me₃N base in methanol solution. The complexes have been fully characterised by elemental analysis, NMR spectrometry, electrospray mass spectrometry, and in several cases, by single-crystal X-ray diffraction studies. The crystallographic studies show that the ligands coordinate as a thiolate in each case with systematic variations in geometric parameters being readily ascribed to the influence of the N-bound substituents. In four of the structures, discernable supramolecular aggregation patterns are evident, leading to loosely associated dimers or chain motifs, the latter mediated by either Au S, N–H N or C–H O interactions. Cytotoxicity data, against the P388 leukemia cell line, and anti-microbial data are also reported.

text: Synthesis, characterisation, supramolecular aggregation and biological activity of phosphine gold(I) complexes with monoanionic thiourea ligands A series of phosphine gold(I) complexes containing monoanionic thiourea ligands has been synthesised by reaction of the appropriate precursor chloro complex, Ph₃PAuCl, Cy₃PAuCl, dppf(AuCl)₂ [dppf = Fe(η⁵-C₅H₄PPh₂)₂] or dppe(AuCl)₂ (dppe = Ph₂PCH₂CH₂PPh₂) with the thiourea and Me₃N base in methanol solution. The complexes have been fully characterised by elemental analysis, NMR spectrometry, electrospray mass spectrometry, and in several cases, by single-crystal X-ray diffraction studies. The crystallographic studies show that the ligands coordinate as a thiolate in each case with systematic variations in geometric parameters being readily ascribed to the influence of the N-bound substituents. In four of the structures, discernable supramolecular aggregation patterns are evident, leading to loosely associated dimers or chain motifs, the latter mediated by either Au S, N–H N or C–H O interactions. Cytotoxicity data, against the P388 leukemia cell line, and anti-microbial data are also reported.

year: 2006-01-01

title: Exploring the music library association mailing list: a text mining approach

authors: Hu, Xiao

abstract: Music librarians and people pursuing music librarianship have exchanged emails via the Music Library Association Mailing List (MLA-L) for decades. The list archive is an invaluable resource to discover new insights on music information retrieval from the perspective of the music librarian community. This study analyzes a corpus of 53,648 emails posted on MLA-L from 2000 to 2016 by using text mining and quantitative analysis methods. In addition to descriptive analysis, main topics of discussions and their trends over the years are identified through topic modeling. We also compare messages that stimulated discussions to those that did not. Inspection of semantic topics reveals insights complementary to previous topic analyses of other Music Information Retrieval (MIR) related resources.

text: Exploring the music library association mailing list: a text mining approach Music librarians and people pursuing music librarianship have exchanged emails via the Music Library Association Mailing List (MLA-L) for decades. The list archive is an invaluable resource to discover new insights on music information retrieval from the perspective of the music librarian community. This study analyzes a corpus of 53,648 emails posted on MLA-L from 2000 to 2016 by using text mining and quantitative analysis methods. In addition to descriptive analysis, main topics of discussions and their trends over the years are identified through topic modeling. We also compare messages that stimulated discussions to those that did not. Inspection of semantic topics reveals insights complementary to previous topic analyses of other Music Information Retrieval (MIR) related resources.

year: 2017

title: Taku manatawa, taku manapou. The learning of te reo Māori in adulthood: Perceptions of its contribution to overall wellbeing

authors: Rolleston, Jamie Huia

subjects: maori

abstract: Ko te tāhuhu o tēnei whare rangahau ko te toiora o te tangata. Ko te tūāpapa o te whare, ko te reo Māori. E toru ngā pou tūhono i te tāhuhu ki te papa, mō tēnei rangahau ko aua pou ko te oranga wairua, ko te oranga whānau, ko te oranga tinana. Ko tā tēnei rangahau he āta mātai i aua pou e toru e toko ana i te toiora o te tangata, ā, kia mātai hoki i te hononga o te reo Māori ki aua pou e toru me te toiora tangata.
Ko te pātai matua kei te aroaro o tēnei rangahau ko tēnei : He aha ngā hua o te ako i te reo Māori hei reo tuarua mō te hunga pakeke ake i te tekau mā waru tau?
E toru ngā wāhanga o te pātai matua:
1. He aha ngā hua ā-wairua?
2. He aha ngā hua ā-whānau?
3. He aha ngā hua ā-tinana?
E toru hoki ngā huarahi i whāia ai kia rapua he whakautu ki aua pātai. Tuatahi ake, i tirohia ngā mātātuhi maha e hāngai ana ki te toiora tangata (Upoko tuarua), arā, ko ngā kōrero a ngā mātanga o te ao whānui, o te ao Māori hoki kua whakawhārikitia kētia ki runga i tēnei kaupapa. Ka rua, i tīmata āku ake ketuketunga ki tētahi pākiki ā-ipurangi, ā, i tukuna atu tēnā ki te marea kia whai māramatanga mō ngā momo pānga a te reo Māori ki a rātou (Upoko tuatoru). Ka mutu, i uiuitia tokorima ngā tāngata kia rongo ai i ō rātou wheako ako i te reo me ngā hua i puta mai ki a rātou (Upoko tuawhā).
E ai ki te hunga i whai wāhi mai ki tēnei rangahau ko te hua nui o te reo Māori ko te whai hononga ki te ao Māori me te tuakiri Māori. I puta mai tēnei kōrero i roto i te pākiki me ngā uiuinga. He mātotoru ngā kōrero a te hunga nei mō te kimi i te mea ngaro, ā, mā te ako i te reo Māori i kitea te mea i te ngaro, anō nei i whakakīkīngia tētahi rua ki roto i te tangata. I roto i te pākiki me ngā uiuinga i kumea mai ai i te hunga nei ngā kōrero mō ō rātou oranga i mua i te ako i te reo, i te tīmatanga o te ako i te reo, me te nāianei hoki, ā, he mārakerake noa te kitea he hoa haere te whanaketanga o te reo Māori me te whanaketanga o te taha Māori o te tangata me tōna māramatanga ki a ia anō, ā, mā reira e piki ai he taha toiora o te tangata. I tua atu i wēnei hua, he maha kē atu ngā hua o te reo i puta mai ai i te rangahau nei, ko te whai hononga ki te taiao, ki te whakapapa, ko te whakapiki māia, ā, ko te whai mahi hoki ētahi o ngā hua i tino kitea i roto i ngā whakautu a tēnei hunga.

text: Taku manatawa, taku manapou. The learning of te reo Māori in adulthood: Perceptions of its contribution to overall wellbeing Ko te tāhuhu o tēnei whare rangahau ko te toiora o te tangata. Ko te tūāpapa o te whare, ko te reo Māori. E toru ngā pou tūhono i te tāhuhu ki te papa, mō tēnei rangahau ko aua pou ko te oranga wairua, ko te oranga whānau, ko te oranga tinana. Ko tā tēnei rangahau he āta mātai i aua pou e toru e toko ana i te toiora o te tangata, ā, kia mātai hoki i te hononga o te reo Māori ki aua pou e toru me te toiora tangata.
Ko te pātai matua kei te aroaro o tēnei rangahau ko tēnei : He aha ngā hua o te ako i te reo Māori hei reo tuarua mō te hunga pakeke ake i te tekau mā waru tau?
E toru ngā wāhanga o te pātai matua:
1. He aha ngā hua ā-wairua?
2. He aha ngā hua ā-whānau?
3. He aha ngā hua ā-tinana?
E toru hoki ngā huarahi i whāia ai kia rapua he whakautu ki aua pātai. Tuatahi ake, i tirohia ngā mātātuhi maha e hāngai ana ki te toiora tangata (Upoko tuarua), arā, ko ngā kōrero a ngā mātanga o te ao whānui, o te ao Māori hoki kua whakawhārikitia kētia ki runga i tēnei kaupapa. Ka rua, i tīmata āku ake ketuketunga ki tētahi pākiki ā-ipurangi, ā, i tukuna atu tēnā ki te marea kia whai māramatanga mō ngā momo pānga a te reo Māori ki a rātou (Upoko tuatoru). Ka mutu, i uiuitia tokorima ngā tāngata kia rongo ai i ō rātou wheako ako i te reo me ngā hua i puta mai ki a rātou (Upoko tuawhā).
E ai ki te hunga i whai wāhi mai ki tēnei rangahau ko te hua nui o te reo Māori ko te whai hononga ki te ao Māori me te tuakiri Māori. I puta mai tēnei kōrero i roto i te pākiki me ngā uiuinga. He mātotoru ngā kōrero a te hunga nei mō te kimi i te mea ngaro, ā, mā te ako i te reo Māori i kitea te mea i te ngaro, anō nei i whakakīkīngia tētahi rua ki roto i te tangata. I roto i te pākiki me ngā uiuinga i kumea mai ai i te hunga nei ngā kōrero mō ō rātou oranga i mua i te ako i te reo, i te tīmatanga o te ako i te reo, me te nāianei hoki, ā, he mārakerake noa te kitea he hoa haere te whanaketanga o te reo Māori me te whanaketanga o te taha Māori o te tangata me tōna māramatanga ki a ia anō, ā, mā reira e piki ai he taha toiora o te tangata. I tua atu i wēnei hua, he maha kē atu ngā hua o te reo i puta mai ai i te rangahau nei, ko te whai hononga ki te taiao, ki te whakapapa, ko te whakapiki māia, ā, ko te whai mahi hoki ētahi o ngā hua i tino kitea i roto i ngā whakautu a tēnei hunga.

year: 2015