title: PATHA's vision for transgender healthcare under the current health reforms

authors: Veale, Jaimie

abstract: Aim: The Aotearoa New Zealand healthcare system does not adequately meet the needs of transgender people. Due to healthcare reforms and increases in funding and awareness of transgender health, the Ministry of Health has met with the Professional Association for Transgender Health Aotearoa (PATHA) to discuss ways to improve the healthcare system. We developed a vision for a transgender healthcare document to enable a process for our members to collaborate and to increase transparency about what advice PATHA has provided to the Ministry. Method: Feedback from PATHA’s committees was incorporated into a draft document, which was then sent to all PATHA members for further feedback and collaboration. Results: PATHA proposes improvements to transgender healthcare that are centred around a new transgender health resourcing hub, which should operate according to a Te Tiriti o Waitangi framework, provide national coordination of a distributed model of care, provide resourcing (including education) for primary care and actively work to increase provision and equity of gender affirming surgeries. In order to be effective, the new resourcing hub would utilise peer health navigators, provide education and professional development, promote healing-focussed care and incorporate transgender community leadership and accountability. Conclusions: These improvements would allow for the best practices from existing regional programmes to be implemented throughout the healthcare system. The proposed changes align with the goals of the healthcare reforms to make healthcare for transgender people more equitable, accessible and cohesive.

text: PATHA's vision for transgender healthcare under the current health reforms Aim: The Aotearoa New Zealand healthcare system does not adequately meet the needs of transgender people. Due to healthcare reforms and increases in funding and awareness of transgender health, the Ministry of Health has met with the Professional Association for Transgender Health Aotearoa (PATHA) to discuss ways to improve the healthcare system. We developed a vision for a transgender healthcare document to enable a process for our members to collaborate and to increase transparency about what advice PATHA has provided to the Ministry. Method: Feedback from PATHA’s committees was incorporated into a draft document, which was then sent to all PATHA members for further feedback and collaboration. Results: PATHA proposes improvements to transgender healthcare that are centred around a new transgender health resourcing hub, which should operate according to a Te Tiriti o Waitangi framework, provide national coordination of a distributed model of care, provide resourcing (including education) for primary care and actively work to increase provision and equity of gender affirming surgeries. In order to be effective, the new resourcing hub would utilise peer health navigators, provide education and professional development, promote healing-focussed care and incorporate transgender community leadership and accountability. Conclusions: These improvements would allow for the best practices from existing regional programmes to be implemented throughout the healthcare system. The proposed changes align with the goals of the healthcare reforms to make healthcare for transgender people more equitable, accessible and cohesive.

year: 2023

title: Equilibration of D-Glucaric Acid in Aqueous Solution

authors: Brown, Jolene Mary

subjects: D-glucaric acid

abstract: Abstract

The equilibrium of aqueous D-glucaric acid was investigated via Nuclear Magnetic Resonance (NMR) spectroscopy. The NMR spectra of all four species (D-glucaric acid, D-glucaro-1,4-lactone, D-glucaro-6,3- lactone and D-glucaro-1,4;6,3-lactone) were assigned.

A 1H NMR spectroscopy method was developed to investigate the kinetics of equilibration of the starting species (D-glucaro-1,4-lactone and D-glucaro-1,4;6,3-dilactone). The equilibration was investigated under neutral conditions as well as conditions with increasing acidity. 

Each experiment set contained 50-100 1HNMR spectroscopy experiments that were run on the same sample using a program that built in delays. Dimethyl sulfoxide was used as an internal standard, and its signal size was used as a scale to report the changes in relative concentration of the four species throughout the experiment sets.

Under neutral conditions D-glucaro-1,4-lactone is relatively stable against equilibration, while D-glucaro-1,4;6,3-dilactone is not. Under acidic conditions both compounds equilibrate within approximately 30,000 seconds. After equilibration under acidic conditions D-glucaric acid is the dominant species, while the relative concentration of D-glucaro-1,4-lactone is slightly higher than that of D-glucaro-6,3-lactone. The relative equilibrium concentration of D-glucaro-1,4;6,3-dilactone is low.

A mechanism for the equilibration of aqueous D-glucaric acid was proposed and equilibrium constants and estimates of rate constants were derived from the experimental data. These rate constants were used in MATLAB simulations that were compared to the experimental data. MATLAB simulations were used to alter the rate constants to improve the fits between experimental data and simulated data.

text: Equilibration of D-Glucaric Acid in Aqueous Solution Abstract

The equilibrium of aqueous D-glucaric acid was investigated via Nuclear Magnetic Resonance (NMR) spectroscopy. The NMR spectra of all four species (D-glucaric acid, D-glucaro-1,4-lactone, D-glucaro-6,3- lactone and D-glucaro-1,4;6,3-lactone) were assigned.

A 1H NMR spectroscopy method was developed to investigate the kinetics of equilibration of the starting species (D-glucaro-1,4-lactone and D-glucaro-1,4;6,3-dilactone). The equilibration was investigated under neutral conditions as well as conditions with increasing acidity. 

Each experiment set contained 50-100 1HNMR spectroscopy experiments that were run on the same sample using a program that built in delays. Dimethyl sulfoxide was used as an internal standard, and its signal size was used as a scale to report the changes in relative concentration of the four species throughout the experiment sets.

Under neutral conditions D-glucaro-1,4-lactone is relatively stable against equilibration, while D-glucaro-1,4;6,3-dilactone is not. Under acidic conditions both compounds equilibrate within approximately 30,000 seconds. After equilibration under acidic conditions D-glucaric acid is the dominant species, while the relative concentration of D-glucaro-1,4-lactone is slightly higher than that of D-glucaro-6,3-lactone. The relative equilibrium concentration of D-glucaro-1,4;6,3-dilactone is low.

A mechanism for the equilibration of aqueous D-glucaric acid was proposed and equilibrium constants and estimates of rate constants were derived from the experimental data. These rate constants were used in MATLAB simulations that were compared to the experimental data. MATLAB simulations were used to alter the rate constants to improve the fits between experimental data and simulated data.

year: 2007

title: Political critique and genealogical vision in te oriori a Rihi Puhiwahine, 1870s

authors: Iti Prendergast, Sam

abstract: Long before twentieth-century scholars developed the language to describe 'settler colonialism', nineteenth-century Māori writers, composers, and storytellers critiqued British imperialism and theorized colonial violence. In mōteatea, letters, and kōrero heke iho (narratives passed down), tūpuna Māori asked what British colonial settlement would mean for te ao Māori, the Māori world. As they reflected on the changes wrought by imperialism, tūpuna offered guidance for future uri (descendants). This is an article about the ways that one wahine Māori critiqued colonization and imagined Māori futures in the context of mid-nineteenth-century colonial invasion. More specifically, it is an article about how Rihi Puhiwahine, a renowned composer, guided her descendants through a world disfigured by British imperialism.

text: Political critique and genealogical vision in te oriori a Rihi Puhiwahine, 1870s Long before twentieth-century scholars developed the language to describe 'settler colonialism', nineteenth-century Māori writers, composers, and storytellers critiqued British imperialism and theorized colonial violence. In mōteatea, letters, and kōrero heke iho (narratives passed down), tūpuna Māori asked what British colonial settlement would mean for te ao Māori, the Māori world. As they reflected on the changes wrought by imperialism, tūpuna offered guidance for future uri (descendants). This is an article about the ways that one wahine Māori critiqued colonization and imagined Māori futures in the context of mid-nineteenth-century colonial invasion. More specifically, it is an article about how Rihi Puhiwahine, a renowned composer, guided her descendants through a world disfigured by British imperialism.

year: 2024