title: Low-Cost α+β PM Ti Alloys by Fe/Ni Addition to Pure Ti

authors: Bolzoni, Leandro

subjects: Elemental titanium

abstract: Ti and its alloys can deliver a very interesting combination of properties such as low density, high strength, corrosion resistance and biocompatibility and, therefore, are very flexible materials which can be adapted to various applications. Nonetheless, Ti and Ti alloys are only employed in critical applications (i.e. aeronautical and aerospace, nautical, medical, etc.) or in products for leisure. In both of these cases the higher fabrication costs of Ti in comparison to its competitors (i.e. steel and aluminium) is not the limiting factor as it is for many structural applications, especially for mass production (i.e. automotive sector). The use of creative techniques and the decrement of the starting price of Ti have been identified as the two main routes to follow to decrease the fabrication costs. In this study, the production of low-cost α+β Ti alloys has been assessed by combining the addition of cheap alloying elements (in particular a Fe/Ni powder) with the classical powder metallurgy route (pressing and sintering). Physical and mechanical properties as well as microstructural analysis of these low-cost alloys were measured and correlated to the processing parameters used to sinter them. It is found that the low-cost Ti alloys show similar behaviour to conventional α+β Ti alloys and, thus, have the potential to be used for non-critical applications.

text: Low-Cost α+β PM Ti Alloys by Fe/Ni Addition to Pure Ti Ti and its alloys can deliver a very interesting combination of properties such as low density, high strength, corrosion resistance and biocompatibility and, therefore, are very flexible materials which can be adapted to various applications. Nonetheless, Ti and Ti alloys are only employed in critical applications (i.e. aeronautical and aerospace, nautical, medical, etc.) or in products for leisure. In both of these cases the higher fabrication costs of Ti in comparison to its competitors (i.e. steel and aluminium) is not the limiting factor as it is for many structural applications, especially for mass production (i.e. automotive sector). The use of creative techniques and the decrement of the starting price of Ti have been identified as the two main routes to follow to decrease the fabrication costs. In this study, the production of low-cost α+β Ti alloys has been assessed by combining the addition of cheap alloying elements (in particular a Fe/Ni powder) with the classical powder metallurgy route (pressing and sintering). Physical and mechanical properties as well as microstructural analysis of these low-cost alloys were measured and correlated to the processing parameters used to sinter them. It is found that the low-cost Ti alloys show similar behaviour to conventional α+β Ti alloys and, thus, have the potential to be used for non-critical applications.

year: 2016

title: The relative effectiveness of alternative treatments for young children with attention deficit hyperactivity disorder

authors: Heriot, S.A.

abstract: The objective of this study was to evaluate the relative effectiveness of pharmacological and behavioural interventions for young children diagnosed with Attention Deficit Hyperactivity Disorder. A randomised between-groups (2 x 2) double blind design was used to compare four treatment conditions: (a) 0.3mg/kg methylphenidate and parent training programme; (b) 0.3mg/kg methylphenidate and parent support group; (c) placebo medication and parent training; and (d) placebo medication and parent support group. Treatment duration was approximately 8 weeks. The 16 families who completed the study involved children aged from 3 to 5 years and their parents (typically their mothers). All children met stringent diagnostic criteria for Attention Deficit Hyperactivity Disorder and five children also met diagnostic criteria for Oppositional Defiant Disorder. Changes were assessed on parent and teacher rating scales that measured problems with attention, activity and impulse control and oppositional/defiant behaviours, direct observation during compliance and attention tasks, cognitive measures (Continuous Performance Task), and parenting and family factors. Analysis of results showed that either active treatment component (i.e., methylphenidate versus parent training) was not better than the other. The combination of active treatment components however led to significant improvements in teacher ratings of behaviour associated with Attention Deficit Hyperactivity Disorder and oppositional defiant behaviour with a similar, although generally statistically nonsignificant, trend in parent ratings. There was a significant and large degree of variability in performance on the cognitive measures and statistical analysis of group differences was not feasible; however, examination of individual data indicated increases in sustained attention and ability to inhibit behaviour for all children receiving combined active treatments. During a compliance task, the number of repeat commands issued by mothers decreased and levels of child compliance increased significantly from pre- to post-intervention levels for the total sample, irrespective of treatment condition. The quality of family relationships also improved for the total sample. At post-intervention, 7 out of 16 children no longer met diagnostic criteria for Attention Deficit Hyperactivity Disorder and 2 out of 5 no longer met criteria for Oppositional Defiant Disorder. Several independent variables, such as gender, marital status, co-existing disorder, severity of behavioural problems, and level of parental warmth and family relationships, were found not to be predictive of post-intervention status. Findings are discussed within the framework of a transactional model. Analysis of the current data set indicates that successful outcomes for young children, at least in the short term, are more likely following combined treatments. Outcomes however may depend less upon the type of treatment per se than on whether treatment leads to changes in critical child-parent interactions, such as improvement in parental attitudes and positive attention towards the child.

text: The relative effectiveness of alternative treatments for young children with attention deficit hyperactivity disorder The objective of this study was to evaluate the relative effectiveness of pharmacological and behavioural interventions for young children diagnosed with Attention Deficit Hyperactivity Disorder. A randomised between-groups (2 x 2) double blind design was used to compare four treatment conditions: (a) 0.3mg/kg methylphenidate and parent training programme; (b) 0.3mg/kg methylphenidate and parent support group; (c) placebo medication and parent training; and (d) placebo medication and parent support group. Treatment duration was approximately 8 weeks. The 16 families who completed the study involved children aged from 3 to 5 years and their parents (typically their mothers). All children met stringent diagnostic criteria for Attention Deficit Hyperactivity Disorder and five children also met diagnostic criteria for Oppositional Defiant Disorder. Changes were assessed on parent and teacher rating scales that measured problems with attention, activity and impulse control and oppositional/defiant behaviours, direct observation during compliance and attention tasks, cognitive measures (Continuous Performance Task), and parenting and family factors. Analysis of results showed that either active treatment component (i.e., methylphenidate versus parent training) was not better than the other. The combination of active treatment components however led to significant improvements in teacher ratings of behaviour associated with Attention Deficit Hyperactivity Disorder and oppositional defiant behaviour with a similar, although generally statistically nonsignificant, trend in parent ratings. There was a significant and large degree of variability in performance on the cognitive measures and statistical analysis of group differences was not feasible; however, examination of individual data indicated increases in sustained attention and ability to inhibit behaviour for all children receiving combined active treatments. During a compliance task, the number of repeat commands issued by mothers decreased and levels of child compliance increased significantly from pre- to post-intervention levels for the total sample, irrespective of treatment condition. The quality of family relationships also improved for the total sample. At post-intervention, 7 out of 16 children no longer met diagnostic criteria for Attention Deficit Hyperactivity Disorder and 2 out of 5 no longer met criteria for Oppositional Defiant Disorder. Several independent variables, such as gender, marital status, co-existing disorder, severity of behavioural problems, and level of parental warmth and family relationships, were found not to be predictive of post-intervention status. Findings are discussed within the framework of a transactional model. Analysis of the current data set indicates that successful outcomes for young children, at least in the short term, are more likely following combined treatments. Outcomes however may depend less upon the type of treatment per se than on whether treatment leads to changes in critical child-parent interactions, such as improvement in parental attitudes and positive attention towards the child.

year: 1999

title: He Pikinga Waiora: Supporting Maori health organisations to respond to pre-diabetes

authors: Beaton, Angela

subjects: Science & Technology

abstract: Background
Type 2 Diabetes (T2D) is a common long-term condition affecting the health and wellbeing of New Zealanders; one in every four New Zealanders is pre-diabetic. Māori, the Indigenous people of New Zealand, are at an increased risk of developing pre-diabetes and T2D and there are significant inequities between Māori and non-Māori for T2D complications. The purpose of this study was to explore the questions of how the strengths of Māori heath organisations may be leveraged, and how the barriers and constraints experienced by Māori health organisations may be negotiated, for the benefit of Māori; and from a systems perspective, to identify strategic opportunities that may be considered and applied by Māori health organisations, funders and policy makers to respond more effectively to pre-diabetes and reduce health inequities between Māori and non-Māori.

Methods
Utilising case study methodology, a range of data sources were triangulated including nine semi-structured interviews, documents, and a diabetes system map to identify possible strategic opportunities for key stakeholders to respond more effectively to pre-diabetes.

Results
Key themes and possible actions to improve health outcomes for Māori with pre-diabetes include: (1) Recognising Māori health organisations as conduits for the community voice and influential partners in the community to effect change; (2) Strengthened partnerships with Māori health organisations for community benefit and to support measurable, evidence-based change and service delivery, particularly when Māori knowledge systems are viewed alongside a Western scientific approach; and (3) Intersectoral integration of health and social services to support provision of whānau-centred care and influence the social determinants of health and local environment.
Conclusions
Māori health organisations are important actors in systems seeking to improve outcomes and eliminate health inequities. Support from funders and policy makers will be required to build on the strengths of these organisations and to overcome system challenges. To realise improved health outcomes for Māori, the value placed on whānau and community perspectives not only needs to be acknowledged in the implementation of health interventions, health and social policies and funding arrangements, but performance measures, service design and delivery must evolve to accommodate these perspectives in practice.

text: He Pikinga Waiora: Supporting Maori health organisations to respond to pre-diabetes Background
Type 2 Diabetes (T2D) is a common long-term condition affecting the health and wellbeing of New Zealanders; one in every four New Zealanders is pre-diabetic. Māori, the Indigenous people of New Zealand, are at an increased risk of developing pre-diabetes and T2D and there are significant inequities between Māori and non-Māori for T2D complications. The purpose of this study was to explore the questions of how the strengths of Māori heath organisations may be leveraged, and how the barriers and constraints experienced by Māori health organisations may be negotiated, for the benefit of Māori; and from a systems perspective, to identify strategic opportunities that may be considered and applied by Māori health organisations, funders and policy makers to respond more effectively to pre-diabetes and reduce health inequities between Māori and non-Māori.

Methods
Utilising case study methodology, a range of data sources were triangulated including nine semi-structured interviews, documents, and a diabetes system map to identify possible strategic opportunities for key stakeholders to respond more effectively to pre-diabetes.

Results
Key themes and possible actions to improve health outcomes for Māori with pre-diabetes include: (1) Recognising Māori health organisations as conduits for the community voice and influential partners in the community to effect change; (2) Strengthened partnerships with Māori health organisations for community benefit and to support measurable, evidence-based change and service delivery, particularly when Māori knowledge systems are viewed alongside a Western scientific approach; and (3) Intersectoral integration of health and social services to support provision of whānau-centred care and influence the social determinants of health and local environment.
Conclusions
Māori health organisations are important actors in systems seeking to improve outcomes and eliminate health inequities. Support from funders and policy makers will be required to build on the strengths of these organisations and to overcome system challenges. To realise improved health outcomes for Māori, the value placed on whānau and community perspectives not only needs to be acknowledged in the implementation of health interventions, health and social policies and funding arrangements, but performance measures, service design and delivery must evolve to accommodate these perspectives in practice.

year: 2019