title: Treatment and survival of Asian women diagnosed with breast cancer in New Zealand

authors: Lao, Chunhuan

subjects: Science & Technology

abstract: Purpose
This study aims to examine the differences in characteristics, treatment and survival between Asian and European women diagnosed with stage I–III breast cancer in New Zealand.

Methods
The studied population included European women and Asian women diagnosed with stage I–III breast cancer between June 2000 and May 2013 identified from the combined Waikato and Auckland Breast Cancer Registers. Characteristics and treatment were compared between Asian and European women. Kaplan–Meier method was used to examine the survival difference. Cox proportional hazards model was used to estimate the hazard ratio (HR) of mortality.

Results
The studied cohort included 8608 European and 949 Asian women. Asian women were younger, had less comorbidities and were less likely to be obese than European women. Asian women were more likely to have grade 3, larger and HER2+  breast cancers. Asian women were more likely to receive mastectomy, less likely to have reconstruction after mastectomy, less likely to have chemotherapy, less likely to be treated with trastuzumab if HER2+, and had better adherence to endocrine therapy (adjusted odds ratio: 1.54; 95% CI 1.22–1.93). Asian women had better cancer-specific survival and all-cause survival than European women. The adjusted HR of cancer-specific mortality and all-cause mortality were 0.64 (95% CI 0.49–0.82) and 0.68 (95% CI 0.55–0.84), respectively.

Conclusions
Asian women are more likely to have high grade, larger and HER2+ breast cancers than European women. In spite of this, they had better breast cancer outcomes. Possible explanations include the differences in adherence to endocrine therapy, age, BMI and comorbidities.

text: Treatment and survival of Asian women diagnosed with breast cancer in New Zealand Purpose
This study aims to examine the differences in characteristics, treatment and survival between Asian and European women diagnosed with stage I–III breast cancer in New Zealand.

Methods
The studied population included European women and Asian women diagnosed with stage I–III breast cancer between June 2000 and May 2013 identified from the combined Waikato and Auckland Breast Cancer Registers. Characteristics and treatment were compared between Asian and European women. Kaplan–Meier method was used to examine the survival difference. Cox proportional hazards model was used to estimate the hazard ratio (HR) of mortality.

Results
The studied cohort included 8608 European and 949 Asian women. Asian women were younger, had less comorbidities and were less likely to be obese than European women. Asian women were more likely to have grade 3, larger and HER2+  breast cancers. Asian women were more likely to receive mastectomy, less likely to have reconstruction after mastectomy, less likely to have chemotherapy, less likely to be treated with trastuzumab if HER2+, and had better adherence to endocrine therapy (adjusted odds ratio: 1.54; 95% CI 1.22–1.93). Asian women had better cancer-specific survival and all-cause survival than European women. The adjusted HR of cancer-specific mortality and all-cause mortality were 0.64 (95% CI 0.49–0.82) and 0.68 (95% CI 0.55–0.84), respectively.

Conclusions
Asian women are more likely to have high grade, larger and HER2+ breast cancers than European women. In spite of this, they had better breast cancer outcomes. Possible explanations include the differences in adherence to endocrine therapy, age, BMI and comorbidities.

year: 2019

title: Management to facilitate compliance with global conventions during hazardous and toxic waste cleanup projects in Asia

authors: McDowall, Ron Laurence

abstract: The management of hazardous and toxic waste projects in Asia (especially that related to intractable chemicals) has had a less than acceptable performance profile during the last 20 years. There have been numerous documented cases of management and systems failures in intractable chemical recovery projects, despite the establishment of global conventions designed to avoid such problems. 
A research programme was undertaken with the aim of producing a management model for companies to help prevent such failures in the future. The research began in the field with an exploration of management culture and its impact on project management. This involved multiple visits to five Asian countries and interviewing people involved in intractable waste management at both strategic and operational levels and reviewing project records. Personnel in government departments, particularly the "competent authority", were interviewed to gain insights into the applied management culture within the five countries studied. 
The various international conventions or regulations regarding hazardous waste and its management, were researched for their interdependence and effectiveness. The research concentrated on the "Management Plans" or "Environmental Management Systems" that reside within these conventions in order to establish a benchmark of expectation concerning standards of management and organisation that would be required of a member state to discharge its obligations under the conventions. This work involved the author attending several meetings and conferences of the parties to the UNEP Basel Convention, as well as attendance at many Technical Working Groups over several years.
Complexity theory and uncertainty theory, along with emergent theory and innovation adoption theory were researched. The outcome of this research clearly suggested that a multidimensional matrix-based approach could be successful in providing companies with a strategic management model that, if applied, could enable them to manage large scale intractable projects effectively in compliance with the conventions. The hypothesis of this work is that Duncan's matrix model can be reverse applied to the external environmental elements and components, combined with the mutual adaptation model (i.e.: technology/organisational mutual adaptation), therefore establishing an integrated multidimensional model of adaptation. 
The mutual adaptation approach was subsequently used to frame a series of questions that formed the basis of four field surveys. These surveys were applied at different times over a five year period, covering ten projects in China and Taiwan, and involving interviews with a total of 100 executives, who were asked a total of 96 questions across the four surveys, resulting in 9600 responses. The first two surveys were conducted close together in time with the third and fourth later in the process and thus could be considered retrospective. The respondents included project managers, engineers, technicians, company accountants, marketing managers and site leaders.
The data collected validated the hypothesis and established that complexity management was an element of those companies that successfully adopted external technology and systems and in fact were also engaged in reversing the technology back to the originators. The data also indicated that those companies not engaging in complexity management were not reversing technology adoption. An integrated mutual adaptation model was developed from the characterisation matrices and consequently a two-dimensional model of singularity. The final singularity model can be applied at an organisation's strategic level, so as to provide an organisational capacity for compliance with environmentally sound management practices as demanded by the international hazardous waste conventions.

text: Management to facilitate compliance with global conventions during hazardous and toxic waste cleanup projects in Asia The management of hazardous and toxic waste projects in Asia (especially that related to intractable chemicals) has had a less than acceptable performance profile during the last 20 years. There have been numerous documented cases of management and systems failures in intractable chemical recovery projects, despite the establishment of global conventions designed to avoid such problems. 
A research programme was undertaken with the aim of producing a management model for companies to help prevent such failures in the future. The research began in the field with an exploration of management culture and its impact on project management. This involved multiple visits to five Asian countries and interviewing people involved in intractable waste management at both strategic and operational levels and reviewing project records. Personnel in government departments, particularly the "competent authority", were interviewed to gain insights into the applied management culture within the five countries studied. 
The various international conventions or regulations regarding hazardous waste and its management, were researched for their interdependence and effectiveness. The research concentrated on the "Management Plans" or "Environmental Management Systems" that reside within these conventions in order to establish a benchmark of expectation concerning standards of management and organisation that would be required of a member state to discharge its obligations under the conventions. This work involved the author attending several meetings and conferences of the parties to the UNEP Basel Convention, as well as attendance at many Technical Working Groups over several years.
Complexity theory and uncertainty theory, along with emergent theory and innovation adoption theory were researched. The outcome of this research clearly suggested that a multidimensional matrix-based approach could be successful in providing companies with a strategic management model that, if applied, could enable them to manage large scale intractable projects effectively in compliance with the conventions. The hypothesis of this work is that Duncan's matrix model can be reverse applied to the external environmental elements and components, combined with the mutual adaptation model (i.e.: technology/organisational mutual adaptation), therefore establishing an integrated multidimensional model of adaptation. 
The mutual adaptation approach was subsequently used to frame a series of questions that formed the basis of four field surveys. These surveys were applied at different times over a five year period, covering ten projects in China and Taiwan, and involving interviews with a total of 100 executives, who were asked a total of 96 questions across the four surveys, resulting in 9600 responses. The first two surveys were conducted close together in time with the third and fourth later in the process and thus could be considered retrospective. The respondents included project managers, engineers, technicians, company accountants, marketing managers and site leaders.
The data collected validated the hypothesis and established that complexity management was an element of those companies that successfully adopted external technology and systems and in fact were also engaged in reversing the technology back to the originators. The data also indicated that those companies not engaging in complexity management were not reversing technology adoption. An integrated mutual adaptation model was developed from the characterisation matrices and consequently a two-dimensional model of singularity. The final singularity model can be applied at an organisation's strategic level, so as to provide an organisational capacity for compliance with environmentally sound management practices as demanded by the international hazardous waste conventions.

year: 2004

title: An outsider's guide to public oral history in New Zealand

authors: Mahuika, Nepia

subjects: Oral history

abstract: At the beginning of this century, public history in New Zealand was considered a ‘new term’ in historical practice, described as crucial in both ‘the emergence of professional history writing’ and the assertion of ‘cultural nationalism.’¹ In the past decade, scholars here have highlighted its breadth and significance in ‘the employment of historians and the historical method outside academia; in government, private companies, the media, historical societies and museums, as well as those working in private practice.’² Oral history has also become a significant part of public history’s nation-making, key in the collecting of exceptional and ‘ordinary’ public voices.³ For Māori, current definitions of oral and public history are problematic because, as this essay suggests, both are constructed within Pākehā-centric perspectives of history, tradition, orality and what counts as ‘public.’ Public history has been called a ‘slippery process’, often shaped in a contrast between ‘people’s history’ and a ‘search for social cohesion’.4 This search for ‘cohesion’ is a familiar colonial refrain that fuels a healthy native scepticism of public history as yet another settler-centric invention that keeps us on the outside. This essay considers the ways in which public oral history in New Zealand is articulated, noting how this is done within narrow definitions and binaries that displace, ignore, or distort, indigenous perspectives. It suggests a rethinking of oral history as a movement beyond current binaries in the field, and advocates a widening of the meaning of oral sources, methods and politics, in order to include indigenous definitions as legitimately oral and public. This analysis is decolonial, not because it seeks an eradication of nationalism, but because it seeks to disrupt colonial-centric meanings of oral and public history by recentering Māori perspectives as legitimate to the New Zealand public oral history vernacular.

text: An outsider's guide to public oral history in New Zealand At the beginning of this century, public history in New Zealand was considered a ‘new term’ in historical practice, described as crucial in both ‘the emergence of professional history writing’ and the assertion of ‘cultural nationalism.’¹ In the past decade, scholars here have highlighted its breadth and significance in ‘the employment of historians and the historical method outside academia; in government, private companies, the media, historical societies and museums, as well as those working in private practice.’² Oral history has also become a significant part of public history’s nation-making, key in the collecting of exceptional and ‘ordinary’ public voices.³ For Māori, current definitions of oral and public history are problematic because, as this essay suggests, both are constructed within Pākehā-centric perspectives of history, tradition, orality and what counts as ‘public.’ Public history has been called a ‘slippery process’, often shaped in a contrast between ‘people’s history’ and a ‘search for social cohesion’.4 This search for ‘cohesion’ is a familiar colonial refrain that fuels a healthy native scepticism of public history as yet another settler-centric invention that keeps us on the outside. This essay considers the ways in which public oral history in New Zealand is articulated, noting how this is done within narrow definitions and binaries that displace, ignore, or distort, indigenous perspectives. It suggests a rethinking of oral history as a movement beyond current binaries in the field, and advocates a widening of the meaning of oral sources, methods and politics, in order to include indigenous definitions as legitimately oral and public. This analysis is decolonial, not because it seeks an eradication of nationalism, but because it seeks to disrupt colonial-centric meanings of oral and public history by recentering Māori perspectives as legitimate to the New Zealand public oral history vernacular.

year: 2017