title: Diagnostic dilemmas associated with the pinnacle IN vaccine

authors: Cursons, Raymond T.

subjects: Strangles, infection, live vaccine next generation sequencing

abstract: The development of clinical signs of strangles in horses following immunization with a live attenuated vaccine can present a number of diagnostic challenges. Foremost from an epidemiological perspective it is important to ascertain if the infection was due solely to the modified live vaccine, reversion of the vaccine strain to wild-type, recombination between vaccine and wild-type strains or to recent infection with a wild-type strain. To answer these diagnostics challenges we utilized next generation sequencing to confirm that two cases of strangles in previously healthy yearling horses were caused by the vaccine strain. Both isolates recovered from the two cases of vaccine-related strangles contained 67 of the 68 mutations specific for the Pinnacle vaccine. Our data shed new light on the safety of this vaccine and suggest that factors beyond the maturity of the animal’s immune system can influence the development of post-vaccination adverse reactions in some horses

text: Diagnostic dilemmas associated with the pinnacle IN vaccine The development of clinical signs of strangles in horses following immunization with a live attenuated vaccine can present a number of diagnostic challenges. Foremost from an epidemiological perspective it is important to ascertain if the infection was due solely to the modified live vaccine, reversion of the vaccine strain to wild-type, recombination between vaccine and wild-type strains or to recent infection with a wild-type strain. To answer these diagnostics challenges we utilized next generation sequencing to confirm that two cases of strangles in previously healthy yearling horses were caused by the vaccine strain. Both isolates recovered from the two cases of vaccine-related strangles contained 67 of the 68 mutations specific for the Pinnacle vaccine. Our data shed new light on the safety of this vaccine and suggest that factors beyond the maturity of the animal’s immune system can influence the development of post-vaccination adverse reactions in some horses

year: 2015

title: Wonder and empathy in environmental ethics

authors: van Zyl, Liezl

abstract: My aim in this article to argue that wonder is a basic moral capacity, akin to the capacity for empathy, that is required for the virtue of environmental benevolence. I begin by examining Geoffrey Frasz’s account of benevolence as a set of environmental virtues, and I identify a gap that not only threatens the coherence of Frasz’s theory, but also points to an important cause of our widespread apathy toward the environment: the inherently limited and biased nature of the capacity for empathy. My proposal is that the capacity for wonder can fill this gap, that is, I think wonder can play the role in environmental benevolence that empathy plays in interpersonal benevolence.

text: Wonder and empathy in environmental ethics My aim in this article to argue that wonder is a basic moral capacity, akin to the capacity for empathy, that is required for the virtue of environmental benevolence. I begin by examining Geoffrey Frasz’s account of benevolence as a set of environmental virtues, and I identify a gap that not only threatens the coherence of Frasz’s theory, but also points to an important cause of our widespread apathy toward the environment: the inherently limited and biased nature of the capacity for empathy. My proposal is that the capacity for wonder can fill this gap, that is, I think wonder can play the role in environmental benevolence that empathy plays in interpersonal benevolence.

year: 2025

title: Countering gentrification in Tāmaki Makarau: Towards a framework for urban environmental justice

authors: Terruhn, Jessica

abstract: This policy brief argues for urban policies that actively aim to end gentrification.

Gentrification is intimately tied to state-led processes of urban renewal. Though historically understood as the displacement of low-income households as an unfortunate byproduct of socioeconomic and demographic neighbourhood change, contemporary gentrification is constituted by profit-driven investment decisions that erase undervalued neighbourhoods and their communities in the name of urban renewal (variously referred to as redevelopment, regeneration, renaissance, or revitalisation).

These processes of gentrification fundamentally contribute to environmental injustice. At the same time as creating ‘zones of abundance’, neighbourhood regeneration projects simultaneously (re-)create ‘zones of neglect and sacrifice’, which are burdened with environmental risks. As low-income and ethnic minority households are more likely to either reside in or to be displaced into these neighbourhoods, they are disproportionately exposed to environmental risk factors.

Moreover, gentrification enables and legitimises the exclusion of marginalised communities in multiple ways: 1) it devalues existing places and their residents in favour of regeneration, 2) it displaces longtime residents from regenerated neighbourhoods because of increasing property values, and/or 3) it alienates longtime residents as neighbourhood aesthetics, amenities and services change and become unaffordable and/or irrelevant.

As gentrification contributes to low-income households’ experiences of precarity and severs community ties and place attachments, it generates significant costs to personal and community health and wellbeing as well as social cohesion. The recommendations articulated in this brief emphasise the importance of transformative policy solutions that actively counter gentrification.
These include:
• Equitable investment in urban infrastructure
• Prioritising affordable housing
• Ensuring accessible transportation
• Empowering local communities
• Implementing a Te Tiriti o Waitangi approach to policy development

text: Countering gentrification in Tāmaki Makarau: Towards a framework for urban environmental justice This policy brief argues for urban policies that actively aim to end gentrification.

Gentrification is intimately tied to state-led processes of urban renewal. Though historically understood as the displacement of low-income households as an unfortunate byproduct of socioeconomic and demographic neighbourhood change, contemporary gentrification is constituted by profit-driven investment decisions that erase undervalued neighbourhoods and their communities in the name of urban renewal (variously referred to as redevelopment, regeneration, renaissance, or revitalisation).

These processes of gentrification fundamentally contribute to environmental injustice. At the same time as creating ‘zones of abundance’, neighbourhood regeneration projects simultaneously (re-)create ‘zones of neglect and sacrifice’, which are burdened with environmental risks. As low-income and ethnic minority households are more likely to either reside in or to be displaced into these neighbourhoods, they are disproportionately exposed to environmental risk factors.

Moreover, gentrification enables and legitimises the exclusion of marginalised communities in multiple ways: 1) it devalues existing places and their residents in favour of regeneration, 2) it displaces longtime residents from regenerated neighbourhoods because of increasing property values, and/or 3) it alienates longtime residents as neighbourhood aesthetics, amenities and services change and become unaffordable and/or irrelevant.

As gentrification contributes to low-income households’ experiences of precarity and severs community ties and place attachments, it generates significant costs to personal and community health and wellbeing as well as social cohesion. The recommendations articulated in this brief emphasise the importance of transformative policy solutions that actively counter gentrification.
These include:
• Equitable investment in urban infrastructure
• Prioritising affordable housing
• Ensuring accessible transportation
• Empowering local communities
• Implementing a Te Tiriti o Waitangi approach to policy development

year: 2025