title: Uputaua approach: researching Samoan communities.

authors: Seiuli, Byron Malaela Sotiata

subjects: Pasifika health

abstract: The increasing needs of the Pasifika population in New Zealand, continues to provide researchers and health professionals with the challenge of developing culturally sensitive approaches, which can assess their health and holistic wellbeing. This article discusses the Uputaua Approach; a contextualised therapeutic perspective which makes important connections with Samoa cultural imperatives, as a process of tautua (service) to Samoan and Pasifika people everywhere.

text: Uputaua approach: researching Samoan communities. The increasing needs of the Pasifika population in New Zealand, continues to provide researchers and health professionals with the challenge of developing culturally sensitive approaches, which can assess their health and holistic wellbeing. This article discusses the Uputaua Approach; a contextualised therapeutic perspective which makes important connections with Samoa cultural imperatives, as a process of tautua (service) to Samoan and Pasifika people everywhere.

year: 2013

title: Portimine: a bioactive metabolite from the benthic dinoflagellate Vulcanodinium rugosum

authors: Selwood, Andrew I.

subjects: pinnatoxin

abstract: Portimine, a new polycyclic ether toxin containing a cyclic imine moiety, was isolated from the marine benthic dinoflagellate Vulcanodinium rugosum collected from Northland, New Zealand. The structure of portimine, including the relative configurations, was elucidated by spectroscopic analyses. The cyclic imine moiety consists of an unprecedented five-membered ring with a spiro-link to a cyclohexene ring. This is the only structural similarity to the pinnatoxin group of polycyclic ethers also produced by V. rugosum, which all contain a six-membered cyclic imine ring. The LD50 of portimine to mice by intraperitoneal injection was 1570 μg/kg, indicating a much lower toxicity than many other cyclic imine shellfish toxins. In contrast, portimine was highly toxic to mammalian cells in vitro with an LC50 to P388 cells of 2.7 nM, and activation of caspases indicating apoptotic activity.

text: Portimine: a bioactive metabolite from the benthic dinoflagellate Vulcanodinium rugosum Portimine, a new polycyclic ether toxin containing a cyclic imine moiety, was isolated from the marine benthic dinoflagellate Vulcanodinium rugosum collected from Northland, New Zealand. The structure of portimine, including the relative configurations, was elucidated by spectroscopic analyses. The cyclic imine moiety consists of an unprecedented five-membered ring with a spiro-link to a cyclohexene ring. This is the only structural similarity to the pinnatoxin group of polycyclic ethers also produced by V. rugosum, which all contain a six-membered cyclic imine ring. The LD50 of portimine to mice by intraperitoneal injection was 1570 μg/kg, indicating a much lower toxicity than many other cyclic imine shellfish toxins. In contrast, portimine was highly toxic to mammalian cells in vitro with an LC50 to P388 cells of 2.7 nM, and activation of caspases indicating apoptotic activity.

year: 2013

title: Tikanga Tainui: Tikanga whare wānanga

authors: Roa, Tom

subjects: Tikanga Māori

abstract: This paper is a preliminary report on an ongoing research project begun in 1999. The project involves consultation with Waikato-Tainui, the tāngata whenua of the Waikato region, about the construction of guidelines for University of Waikato staff (both Māori and non-Māori) who are involved in gatherings that call for adherence to Tainui protocols. Here, the emphasis is on guidelines for the conduct of pōwhiri (formal welcomes) on the University Marae.

text: Tikanga Tainui: Tikanga whare wānanga This paper is a preliminary report on an ongoing research project begun in 1999. The project involves consultation with Waikato-Tainui, the tāngata whenua of the Waikato region, about the construction of guidelines for University of Waikato staff (both Māori and non-Māori) who are involved in gatherings that call for adherence to Tainui protocols. Here, the emphasis is on guidelines for the conduct of pōwhiri (formal welcomes) on the University Marae.

year: 2005-09