title: Isolation and identification of a cis-C₈-diol-ester of okadaic acid from Dinophysis acuta in New Zealand

authors: Miles, Christopher O.

subjects: okadaic acid

abstract: A cis-isomer of a C8-diol ester of okadaic acid (1) was isolated during large-scale purification of pectenotoxins (PTXs) from extracts of Dinophysis acuta collected from the west coast of South Island, New Zealand. The compound was identified by NMR spectroscopic and liquid chromatography-mass spectrometry (LC-MS) studies, and is the first reported cis-isomer of an okadaic acid C₈-diol-ester identified in Dinophysis. The more abundant trans-C₈-diol ester of okadaic acid (2) isolated from the same Dinophysis extract was rapidly hydrolyzed to okadaic acid in vitro by the supernatant from green-lipped mussel hepatopancreas.

text: Isolation and identification of a cis-C₈-diol-ester of okadaic acid from Dinophysis acuta in New Zealand A cis-isomer of a C8-diol ester of okadaic acid (1) was isolated during large-scale purification of pectenotoxins (PTXs) from extracts of Dinophysis acuta collected from the west coast of South Island, New Zealand. The compound was identified by NMR spectroscopic and liquid chromatography-mass spectrometry (LC-MS) studies, and is the first reported cis-isomer of an okadaic acid C₈-diol-ester identified in Dinophysis. The more abundant trans-C₈-diol ester of okadaic acid (2) isolated from the same Dinophysis extract was rapidly hydrolyzed to okadaic acid in vitro by the supernatant from green-lipped mussel hepatopancreas.

year: 2006

title: Exhausted men: Making fatigue visible in The Metamorphosis and At Swim-Two-Birds

authors: Burnette, Jessie

subjects: Fatigue

abstract: Though not always immediately recognizable, fatigue and tiredness play a central role in modernist literature. As society placed increasing value on productive, strong, energetic bodies, the growing presence of bodies tired from the effects of overwork, rapid social progress, illness and post-war malaise posed a threat both to society and ideas of the 
able-bodied self. Recumbent bodies challenge expectations of productivity; they remindus of our own bodily fallibility and blur the line between life and death as a visual 
representation of our own mortality. Further, the fatigued body at rest is predominantly associated with the feminine, as has been reflected in much prior academic engagement 
with neurasthenic women in modernist literature. What then are the implications for fatigued men? This thesis traces the previously overlooked depictions and uses of fatigue in two texts that have been the subject of significant analysis: The Metamorphosis by Franz Kafka and At Swim-Two-Birds by Flann O’Brien. Though neither of these texts are inherently medical in nature, I show how fatigue nonetheless plays a central role in each, albeit in quite different ways. By unpacking these contrasting engagements with fatigue and the simultaneous lack of critical interest in fatigue in these texts, I uncover stigmatizing social perceptions of fatigue as deviant, burdensome, and indicative of emasculating weakness. Further, such depictions seem to go unquestioned, suggesting that these beliefs are largely naturalized within Western society. In the current time of pandemic, as society is again increasingly confronted with very visible exhaustion in the form of Long Covid amongst other fatiguing conditions, modernist fiction from the early-twentieth century offers valuable insights into how we engage with fatigue.

text: Exhausted men: Making fatigue visible in The Metamorphosis and At Swim-Two-Birds Though not always immediately recognizable, fatigue and tiredness play a central role in modernist literature. As society placed increasing value on productive, strong, energetic bodies, the growing presence of bodies tired from the effects of overwork, rapid social progress, illness and post-war malaise posed a threat both to society and ideas of the 
able-bodied self. Recumbent bodies challenge expectations of productivity; they remindus of our own bodily fallibility and blur the line between life and death as a visual 
representation of our own mortality. Further, the fatigued body at rest is predominantly associated with the feminine, as has been reflected in much prior academic engagement 
with neurasthenic women in modernist literature. What then are the implications for fatigued men? This thesis traces the previously overlooked depictions and uses of fatigue in two texts that have been the subject of significant analysis: The Metamorphosis by Franz Kafka and At Swim-Two-Birds by Flann O’Brien. Though neither of these texts are inherently medical in nature, I show how fatigue nonetheless plays a central role in each, albeit in quite different ways. By unpacking these contrasting engagements with fatigue and the simultaneous lack of critical interest in fatigue in these texts, I uncover stigmatizing social perceptions of fatigue as deviant, burdensome, and indicative of emasculating weakness. Further, such depictions seem to go unquestioned, suggesting that these beliefs are largely naturalized within Western society. In the current time of pandemic, as society is again increasingly confronted with very visible exhaustion in the form of Long Covid amongst other fatiguing conditions, modernist fiction from the early-twentieth century offers valuable insights into how we engage with fatigue.

year: 2023

title: Imagining our own approaches

authors: Smith, Linda Tuhiwai

abstract: I spent some formative years of my life either in the back of museums or their basements helping my father, a scholar of Māori Studies, and keeping myself out of trouble. In the late 1960s I had one small job in the library basement of the Peabody Museum in Salem, Massachusetts, typing new labels for the captains’ log books of ships that were sailing during the American Revolution. I read most of those journals that consisted of pages and pages of wind directions with the rare glimpse of an encounter with another ship or a list of supplies. Why were we there in Salem when we came from Aotearoa, New Zealand? We were there because Salem was the home base for ships that sailed into the Pacific and returned home with collections of materials from the various Pacific Islands countries they visited. My father was studying elaborately carved items from the Marquesa Islands that looked very much like Māori designs.

text: Imagining our own approaches I spent some formative years of my life either in the back of museums or their basements helping my father, a scholar of Māori Studies, and keeping myself out of trouble. In the late 1960s I had one small job in the library basement of the Peabody Museum in Salem, Massachusetts, typing new labels for the captains’ log books of ships that were sailing during the American Revolution. I read most of those journals that consisted of pages and pages of wind directions with the rare glimpse of an encounter with another ship or a list of supplies. Why were we there in Salem when we came from Aotearoa, New Zealand? We were there because Salem was the home base for ships that sailed into the Pacific and returned home with collections of materials from the various Pacific Islands countries they visited. My father was studying elaborately carved items from the Marquesa Islands that looked very much like Māori designs.

year: 2015