title: Effect of Coriaria arborea on seed banks during primary succession on Mt Tarawera, New Zealand

authors: Clarkson, Beverley R.

subjects: Coriaria arborea

abstract: An experiment was conducted over two years to investigate the effect of Coriaria arborea, a native nitrogen-fixing shrub, on soil seed banks at sites representing a post-volcanic successional sequence on Mt Tarawera, New Zealand. The sites ranged from bare volcanic ash and lapilli substrate, through low-growing pre-Coriaria vegetation, to dense stands of Coriaria scrub. Soils (to a depth of 50 mm) under recently established Coriaria and older stands had more seedlings (1096 and 1585 seedlings 0.4 m-2, respectively) and species (37 and 45 species 0.4 m-2, respectively) emerge than where there was no Coriaria (243-320 seedlings 0.4 m-2, 14-25 species 0.4 m-2) and were the only soils with Coriaria seedlings. In total, 3488 seedlings representing 63 taxa were recorded. Seeds were still germinating after 24 months but rates declined markedly in the second year. For example, Coriaria reached a germination peak at 8 weeks but continued to germinate sporadically over the 2-year period. Tree species present in young forest within 0.5 km of the sites were absent. Establishment of Coriaria greatly accelerated an underlying trend of gradually increasing abundance and diversity of seeds in the soil with vegetation age. Adventive, wind-dispersed, and annual species were over-represented in the seed banks compared with the regional evergreen forest-dominated flora. These proportions are expected to decline as succession to forest gradually occurs.

text: Effect of Coriaria arborea on seed banks during primary succession on Mt Tarawera, New Zealand An experiment was conducted over two years to investigate the effect of Coriaria arborea, a native nitrogen-fixing shrub, on soil seed banks at sites representing a post-volcanic successional sequence on Mt Tarawera, New Zealand. The sites ranged from bare volcanic ash and lapilli substrate, through low-growing pre-Coriaria vegetation, to dense stands of Coriaria scrub. Soils (to a depth of 50 mm) under recently established Coriaria and older stands had more seedlings (1096 and 1585 seedlings 0.4 m-2, respectively) and species (37 and 45 species 0.4 m-2, respectively) emerge than where there was no Coriaria (243-320 seedlings 0.4 m-2, 14-25 species 0.4 m-2) and were the only soils with Coriaria seedlings. In total, 3488 seedlings representing 63 taxa were recorded. Seeds were still germinating after 24 months but rates declined markedly in the second year. For example, Coriaria reached a germination peak at 8 weeks but continued to germinate sporadically over the 2-year period. Tree species present in young forest within 0.5 km of the sites were absent. Establishment of Coriaria greatly accelerated an underlying trend of gradually increasing abundance and diversity of seeds in the soil with vegetation age. Adventive, wind-dispersed, and annual species were over-represented in the seed banks compared with the regional evergreen forest-dominated flora. These proportions are expected to decline as succession to forest gradually occurs.

year: 2002-12-01

title: Acute hypophagia and changes in c-Fos immunoreactivity in adolescent rats treated with low doses of oxytocin and naltrexone.

authors: Head, Mitchell Antony

subjects: neuropeptides

abstract: A recent case report has shown that an adjunctive oxytocin + naltrexone (OT + NTX) treatment promoted more robust hypophagia and body weight reduction than OT alone in an adolescent male with hypothalamic obesity after craniopharyngioma resection. Thus far, there has been no basic research in adolescent laboratory animals that would examine whether the benefit of OT + NTX on appetite extends onto adolescent individuals without surgically induced overeating. Thus, here we examined whether low doses of combined OT + NTX acutely affect post-deprivation intake of energy-dense, standard chow; intake of energy-dense and palatable high-fat high-sugar (HFHS) diet; or calorie-dilute, palaTable 10% sucrose solution without deprivation in adolescent male rats. We assessed whether OT + NTX decreases water intake after water deprivation or produces a conditioned taste aversion (CTA). Finally, by using c-Fos immunoreactivity, we determined changes in activity of feeding-related brain areas after OT + NTX. We found that individual subthreshold doses of OT and NTX decreased feeding induced by energy and by palatability. Significant c-Fos changes were noted in the arcuate and dorsomedial hypothalamic nuclei. The hypophagic doses of OT + NTX did not suppress water intake in thirsty rats and did not cause a CTA, which suggests that feeding reduction is not a secondary effect of gastrointestinal discomfort or changes in thirst processing. We conclude that OT + NTX is an effective drug combination to reduce appetite in adolescent male rats.

text: Acute hypophagia and changes in c-Fos immunoreactivity in adolescent rats treated with low doses of oxytocin and naltrexone. A recent case report has shown that an adjunctive oxytocin + naltrexone (OT + NTX) treatment promoted more robust hypophagia and body weight reduction than OT alone in an adolescent male with hypothalamic obesity after craniopharyngioma resection. Thus far, there has been no basic research in adolescent laboratory animals that would examine whether the benefit of OT + NTX on appetite extends onto adolescent individuals without surgically induced overeating. Thus, here we examined whether low doses of combined OT + NTX acutely affect post-deprivation intake of energy-dense, standard chow; intake of energy-dense and palatable high-fat high-sugar (HFHS) diet; or calorie-dilute, palaTable 10% sucrose solution without deprivation in adolescent male rats. We assessed whether OT + NTX decreases water intake after water deprivation or produces a conditioned taste aversion (CTA). Finally, by using c-Fos immunoreactivity, we determined changes in activity of feeding-related brain areas after OT + NTX. We found that individual subthreshold doses of OT and NTX decreased feeding induced by energy and by palatability. Significant c-Fos changes were noted in the arcuate and dorsomedial hypothalamic nuclei. The hypophagic doses of OT + NTX did not suppress water intake in thirsty rats and did not cause a CTA, which suggests that feeding reduction is not a secondary effect of gastrointestinal discomfort or changes in thirst processing. We conclude that OT + NTX is an effective drug combination to reduce appetite in adolescent male rats.

year: 2021-12-23

title: Hā Ora: secondary care barriers and enablers to early diagnosis of lung cancer for Māori communities.

authors: Kidd, Jacquie

subjects: Barriers

abstract: BACKGROUND: Lung Cancer is the leading cause of cancer deaths in Aotearoa New Zealand. Māori communities in particular have higher incidence and mortality rates from Lung Cancer. Diagnosis of lung cancer at an early stage can allow for curative treatment. This project aimed to document the barriers to early diagnosis and treatment of lung cancer in secondary care for Māori communities. 
METHODS: This project used a kaupapa Māori approach. Nine community hui (focus groups) and nine primary healthcare provider hui were carried out in five rural localities in the Midland region. Community hui included cancer patients, whānau (families), and other community members. Healthcare provider hui comprised staff members at the local primary healthcare centre, including General Practitioners and nurses. Hui data were thematically analysed. 
RESULTS: Barriers and enablers to early diagnosis of lung cancer were categorised into two broad themes: Specialist services and treatment, and whānau journey. The barriers and enablers that participants experienced in specialist services and treatment related to access to care, engagement with specialists, communication with specialist services and cultural values and respect, whereas barriers and enablers relating to the whānau journey focused on agency and the impact on whānau. 
CONCLUSIONS: The study highlighted the need to improve communication within and across healthcare services, the importance of understanding the cultural needs of patients and whānau and a health system strategy that meets these needs. Findings also demonstrated the resilience of Māori and the active efforts of whānau as carers to foster health literacy in future generations.

text: Hā Ora: secondary care barriers and enablers to early diagnosis of lung cancer for Māori communities. BACKGROUND: Lung Cancer is the leading cause of cancer deaths in Aotearoa New Zealand. Māori communities in particular have higher incidence and mortality rates from Lung Cancer. Diagnosis of lung cancer at an early stage can allow for curative treatment. This project aimed to document the barriers to early diagnosis and treatment of lung cancer in secondary care for Māori communities. 
METHODS: This project used a kaupapa Māori approach. Nine community hui (focus groups) and nine primary healthcare provider hui were carried out in five rural localities in the Midland region. Community hui included cancer patients, whānau (families), and other community members. Healthcare provider hui comprised staff members at the local primary healthcare centre, including General Practitioners and nurses. Hui data were thematically analysed. 
RESULTS: Barriers and enablers to early diagnosis of lung cancer were categorised into two broad themes: Specialist services and treatment, and whānau journey. The barriers and enablers that participants experienced in specialist services and treatment related to access to care, engagement with specialists, communication with specialist services and cultural values and respect, whereas barriers and enablers relating to the whānau journey focused on agency and the impact on whānau. 
CONCLUSIONS: The study highlighted the need to improve communication within and across healthcare services, the importance of understanding the cultural needs of patients and whānau and a health system strategy that meets these needs. Findings also demonstrated the resilience of Māori and the active efforts of whānau as carers to foster health literacy in future generations.

year: 2021