title: Developing a minimum data set, known as a core outcome set, for future infertility research

authors: Duffy, J.M.N.

abstract: Background: Complex issues, including a failure to consider the perspectives of people with fertility problems when selecting outcomes, variations in outcome definitions, and outcome reporting bias, make the results of infertility research difficult to interpret.
Objectives: To develop a core outcome set to standardise outcome selection, collection, and reporting across future randomized controlled trials and systematic reviews evaluating potential treatments for infertility.
Methods: Healthcare professionals, researchers, and people with fertility problems were brought together in an open and transparent process using formal consensus science methods including a three-round Delphi survey (372 participants from 41 countries) and consensus development workshop (30 participants from 27 countries) (1).
Results: The core outcome set consists of: (1) viable intrauterine pregnancy confirmed by ultrasound (accounting for singleton, twin, and higher multiple pregnancies); (2) pregnancy loss (accounting for ectopic pregnancy, miscarriage, stillbirth, and termination of pregnancy); (3) live birth; (4) gestational age at delivery; (5) birth weight; (6) neonatal mortality; and (7) major congenital anomaly. Time to pregnancy leading to live birth should be reported when applicable.
Conclusions: Embedding the core outcome set within randomized controlled trials and systematic reviews should ensure the comprehensive selection, collection, and reporting of core outcomes. Research funding bodies, the Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) statement, and over 80 specialty journals, including Cochrane Gynaecology and Fertility Group, Fertility and Sterility, and Human Reproduction, have committed to implementing this core outcome set.

text: Developing a minimum data set, known as a core outcome set, for future infertility research Background: Complex issues, including a failure to consider the perspectives of people with fertility problems when selecting outcomes, variations in outcome definitions, and outcome reporting bias, make the results of infertility research difficult to interpret.
Objectives: To develop a core outcome set to standardise outcome selection, collection, and reporting across future randomized controlled trials and systematic reviews evaluating potential treatments for infertility.
Methods: Healthcare professionals, researchers, and people with fertility problems were brought together in an open and transparent process using formal consensus science methods including a three-round Delphi survey (372 participants from 41 countries) and consensus development workshop (30 participants from 27 countries) (1).
Results: The core outcome set consists of: (1) viable intrauterine pregnancy confirmed by ultrasound (accounting for singleton, twin, and higher multiple pregnancies); (2) pregnancy loss (accounting for ectopic pregnancy, miscarriage, stillbirth, and termination of pregnancy); (3) live birth; (4) gestational age at delivery; (5) birth weight; (6) neonatal mortality; and (7) major congenital anomaly. Time to pregnancy leading to live birth should be reported when applicable.
Conclusions: Embedding the core outcome set within randomized controlled trials and systematic reviews should ensure the comprehensive selection, collection, and reporting of core outcomes. Research funding bodies, the Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) statement, and over 80 specialty journals, including Cochrane Gynaecology and Fertility Group, Fertility and Sterility, and Human Reproduction, have committed to implementing this core outcome set.

year: 2020

title: Guarded operations, refinement and simulation

authors: Reeves, Steve

subjects: computer science

abstract: Simulation rules have long been used as an effective computational means to decide  refinement relations in state-based formalisms. Here we investigate how they might be amended so as to decide the event-based notion of singleton failures refinement of abstract data types or processes that have operations with a "guarded" interpretation.  As the results presented here and found elsewhere in the literature are so sensitive to the details of the definitions used, we have machine-checked our results.

text: Guarded operations, refinement and simulation Simulation rules have long been used as an effective computational means to decide  refinement relations in state-based formalisms. Here we investigate how they might be amended so as to decide the event-based notion of singleton failures refinement of abstract data types or processes that have operations with a "guarded" interpretation.  As the results presented here and found elsewhere in the literature are so sensitive to the details of the definitions used, we have machine-checked our results.

year: 2009-06-10

title: An exploration of wellbeing in Hapū Wānanga through a Te Wheke framework analysis

authors: Hawaikirangi, Lena

subjects: Antenatal education

abstract: Before colonisation, Māori had comprehensive knowledge and practices around pregnancy and childbirth. With colonisation, traditional maternity knowledge and practices were replaced by western medical practices. In more recent times, antenatal education classes have played an essential role in providing information on pregnancy, birth and caring for newborns. Research reports that Māori are less likely to attend antenatal programmes and  have suggested that culturally responsive programmes may encourage better engagement by Māori. Hapū Wānanga is a kaupapa Māori antenatal education programme. No previous research has explored how whānau experience wellbeing through Hapū Wānanga. This research explores how participants experience wellbeing within the Kia Wana  Lakes Baby Service Hapū Wānanga. Three participants, including one couple, and three facilitators were interviewed. Transcripts were analysed through a framework analysis using the Te Wheke model (Pere, 1997), a comprehensive Māori model of health. Findings showed that Hapū Wānanga caters to Māori holistic views of wellbeing, as demonstrated through the Te Wheke Model (Pere, 1997). All participants reported negative experiences with mainstream antenatal services; however, whānau enjoyed their experience at Hapū Wānanga. The two dimensions that influenced participants most were whānaungatanga (kinship ties) and hā ā koro mā ā kuia mā (cultural heritage). Although whānau were empowered by their experience at Hapū Wānanga, they wanted to learn more about parenting and postpartum, mental health. Overall, my findings highlighted that culturally adapted programmes that cater to  holistic models of wellbeing could engage Māori service users in an enjoyable and empowering way. If healthcare providers are to be successful in improving indigenous peoples' wellbeing, they need to prioritise culturally adapted programmes based on holistic models of wellbeing.

text: An exploration of wellbeing in Hapū Wānanga through a Te Wheke framework analysis Before colonisation, Māori had comprehensive knowledge and practices around pregnancy and childbirth. With colonisation, traditional maternity knowledge and practices were replaced by western medical practices. In more recent times, antenatal education classes have played an essential role in providing information on pregnancy, birth and caring for newborns. Research reports that Māori are less likely to attend antenatal programmes and  have suggested that culturally responsive programmes may encourage better engagement by Māori. Hapū Wānanga is a kaupapa Māori antenatal education programme. No previous research has explored how whānau experience wellbeing through Hapū Wānanga. This research explores how participants experience wellbeing within the Kia Wana  Lakes Baby Service Hapū Wānanga. Three participants, including one couple, and three facilitators were interviewed. Transcripts were analysed through a framework analysis using the Te Wheke model (Pere, 1997), a comprehensive Māori model of health. Findings showed that Hapū Wānanga caters to Māori holistic views of wellbeing, as demonstrated through the Te Wheke Model (Pere, 1997). All participants reported negative experiences with mainstream antenatal services; however, whānau enjoyed their experience at Hapū Wānanga. The two dimensions that influenced participants most were whānaungatanga (kinship ties) and hā ā koro mā ā kuia mā (cultural heritage). Although whānau were empowered by their experience at Hapū Wānanga, they wanted to learn more about parenting and postpartum, mental health. Overall, my findings highlighted that culturally adapted programmes that cater to  holistic models of wellbeing could engage Māori service users in an enjoyable and empowering way. If healthcare providers are to be successful in improving indigenous peoples' wellbeing, they need to prioritise culturally adapted programmes based on holistic models of wellbeing.

year: 2021