title: Enzyme Dynamics and Activity: Time-Scale Dependence of Dynamical Transitions in Glutamate Dehydrogenase Solution

authors: Daniel, Roy M.

abstract: We have examined the temperature dependence of motions in a cryosolution of the enzyme glutamate dehydrogenase (GDH) and compared these with activity. Dynamic neutron scattering was performed with two instruments of different energy resolution, permitting the separate determination of the average dynamical mean square displacements on the sub-~100 ps and sub-~5 ns time scales. The results demonstrate a marked dependence on the time scale of the temperature profile of the mean square displacement. The lowest temperature at which anharmonic motion is observed is heavily dependent on the time window of the instrument used to observe the dynamics. Several dynamical transitions (inflexions of the mean squared displacement) are observed in the slower dynamics. Comparison with the temperature profile of the activity of the enzyme in the same solvent reveals dynamical transitions that have no effect on GDH function.

text: Enzyme Dynamics and Activity: Time-Scale Dependence of Dynamical Transitions in Glutamate Dehydrogenase Solution We have examined the temperature dependence of motions in a cryosolution of the enzyme glutamate dehydrogenase (GDH) and compared these with activity. Dynamic neutron scattering was performed with two instruments of different energy resolution, permitting the separate determination of the average dynamical mean square displacements on the sub-~100 ps and sub-~5 ns time scales. The results demonstrate a marked dependence on the time scale of the temperature profile of the mean square displacement. The lowest temperature at which anharmonic motion is observed is heavily dependent on the time window of the instrument used to observe the dynamics. Several dynamical transitions (inflexions of the mean squared displacement) are observed in the slower dynamics. Comparison with the temperature profile of the activity of the enzyme in the same solvent reveals dynamical transitions that have no effect on GDH function.

year: 1999-10

title: The use of paper in everyday student life

authors: Nichols, David M.

subjects: computer science

abstract: The information we encounter in modern life, in developed countries, is a hybrid of the physical and the digital. Personal archiving tools allow users to capture and retrieve aspects of their everyday lives in digital form. In this paper we use a diary study of students’ interactions with paper-based information to inform the design of such archiving tools.

text: The use of paper in everyday student life The information we encounter in modern life, in developed countries, is a hybrid of the physical and the digital. Personal archiving tools allow users to capture and retrieve aspects of their everyday lives in digital form. In this paper we use a diary study of students’ interactions with paper-based information to inform the design of such archiving tools.

year: 2009

title: Growth out of loss: The urban discourses of literatures of the Native American and Māori literary renaissance

authors: Waterman, Jason

subjects: New Zealand

abstract: The seeds of the Native American and Māori Renaissance eras germinated amid sweeping changes in the years immediately following World War II, a time when urbanization and the consequent separation of indigenous peoples from community networks represented a major threat to culturally embedded certainties and destabilized romanticized notions of the past. This article explores parallels between the ways in which Native American and Māori literatures reflect the impact of urbanization at the height of this era and the contribution the authors make to the positive cultural growth that defines their respective renaissance periods.

text: Growth out of loss: The urban discourses of literatures of the Native American and Māori literary renaissance The seeds of the Native American and Māori Renaissance eras germinated amid sweeping changes in the years immediately following World War II, a time when urbanization and the consequent separation of indigenous peoples from community networks represented a major threat to culturally embedded certainties and destabilized romanticized notions of the past. This article explores parallels between the ways in which Native American and Māori literatures reflect the impact of urbanization at the height of this era and the contribution the authors make to the positive cultural growth that defines their respective renaissance periods.

year: 2009-09