title: Overseas social work placements: Can a well-designed workflow contribute to the success of an overseas placement?

authors: Henley, Lee

abstract: This article reflects on the importance of workflow design for students completing field education as part of a social work degree. Specifically, this article examines this in the context of an Aotearoa New Zealand social work student from the University of Waikato (UoW) completing a final placement at a non-governmental organisation (NGO) in Battambang Cambodia, Children’s Future International (CFI). The main body of the article reflects on the advantages of designing an overseas placement approach which is planned to flow from theory development to practice implementation, termed “knowledge development and flow” (Henley et al., in press).

text: Overseas social work placements: Can a well-designed workflow contribute to the success of an overseas placement? This article reflects on the importance of workflow design for students completing field education as part of a social work degree. Specifically, this article examines this in the context of an Aotearoa New Zealand social work student from the University of Waikato (UoW) completing a final placement at a non-governmental organisation (NGO) in Battambang Cambodia, Children’s Future International (CFI). The main body of the article reflects on the advantages of designing an overseas placement approach which is planned to flow from theory development to practice implementation, termed “knowledge development and flow” (Henley et al., in press).

year: 2019

title: Transcriptional changes in response to ketamine ester-analogs SN 35210 and SN 35563 in the rat brain

authors: Jacobson, Gregory M.

subjects: Science & Technology

abstract: Background
Ketamine ester analogs, SN 35210 and SN 35563, demonstrate different pharmacological profiles to ketamine in animal models. Both confer hypnosis with predictably rapid offset yet, paradoxically, SN35563 induces a prolonged anti-nociceptive state. To explore underlying mechanisms, broad transcriptome changes were measured and compared across four relevant target regions of the rat brain.

Results
SN 35563 produced large-scale alteration of gene expression in the Basolateral Amygdala (BLA) and Paraventricular Nucleus of the Thalamus (PVT), in excess of 10x that induced by ketamine and SN 35210. A smaller and quantitatively similar number of gene changes were observed in the Insula (INS) and Nucleus Accumbens (ACB) for all three agents. In the BLA and PVT, SN 35563 caused enrichment for gene pathways related to the function and structure of glutamatergic synapses in respect to: release of neurotransmitter, configuration of postsynaptic AMPA receptors, and the underlying cytoskeletal scaffolding and alignment.

Conclusion
The analgesic ketamine ester analog SN 35563 induces profound large-scale changes in gene expression in key pain-related brain regions reflecting its unique prolonged pharmacodynamic profile.

text: Transcriptional changes in response to ketamine ester-analogs SN 35210 and SN 35563 in the rat brain Background
Ketamine ester analogs, SN 35210 and SN 35563, demonstrate different pharmacological profiles to ketamine in animal models. Both confer hypnosis with predictably rapid offset yet, paradoxically, SN35563 induces a prolonged anti-nociceptive state. To explore underlying mechanisms, broad transcriptome changes were measured and compared across four relevant target regions of the rat brain.

Results
SN 35563 produced large-scale alteration of gene expression in the Basolateral Amygdala (BLA) and Paraventricular Nucleus of the Thalamus (PVT), in excess of 10x that induced by ketamine and SN 35210. A smaller and quantitatively similar number of gene changes were observed in the Insula (INS) and Nucleus Accumbens (ACB) for all three agents. In the BLA and PVT, SN 35563 caused enrichment for gene pathways related to the function and structure of glutamatergic synapses in respect to: release of neurotransmitter, configuration of postsynaptic AMPA receptors, and the underlying cytoskeletal scaffolding and alignment.

Conclusion
The analgesic ketamine ester analog SN 35563 induces profound large-scale changes in gene expression in key pain-related brain regions reflecting its unique prolonged pharmacodynamic profile.

year: 2019

title: He kohikohinga kōrero nō Ngāti Kuia

authors: Hawea, Celia

subjects: Ngāti Kuia

abstract: Ko te tikanga o tēnei mahi rangahau kia whakautu i te pātai e whai ake nei. He aha ngā kōrero-ā-waha, ngā kōrero i roto i ngā pukapuka hoki ka pūmau tonu i ēnei rā mō ngā uri o Ngāti Kuia mō ngā tau kei te heke mai? 

Ko tēnei he kohikohinga nō ngā kōrero o Ngāti Kuia tētahi iwi e noho ana i te Tauihu o te Waka-o-Māui. Ētahi o ngā iwi Māori he maha ngā kōrero e pā ana ki a rātou, engari ko tēnei te pukapuka tuatahi tonu ka tāia e pā ana ki a Ngāti Kuia. Ehara tēnei i te titiro hōhonu, te titiro whānui rānei i ngā kōrero engari he kohikohinga noa iho nō ngā kōrero mō Ngāti Kuia ki roto te pukapuka kotahi. Nā reira, ki te hiahia tētahi kia whāia tēnei huarahi, koinei he tīmatanga, he paku āwhina hoki mōna. 

Ka āhua toru ngā wehenga o te kōrero nei. Ka tīmata i te kupu whakataki, i muri iho ko ngā āhuatanga o te mahi, arā, i pēhea ngā kōrero i kohikohia, ā, ko te whakapapa me ngā tūhonohononga o Ngāti Kuia ki ētahi atu iwi. Ko te wāhanga tuarua, ko te kōrero o nehe rā, arā, ko ngā kōrero mō ngā atua a Tāwhaki rāua ko Māui, he kōrero mō Kupe, he whakataukī, he kōrero hoki mō ngā taniwha o te iwi. Nā, ko te wāhanga tuatoru e pā ana ki ngā tāngata rongonui o Ngāti Kuia, arā, ko Tūtepourangi, ko Tamairangi, ko Hinepoupou, ko Waikura, ko Kehaia.

text: He kohikohinga kōrero nō Ngāti Kuia Ko te tikanga o tēnei mahi rangahau kia whakautu i te pātai e whai ake nei. He aha ngā kōrero-ā-waha, ngā kōrero i roto i ngā pukapuka hoki ka pūmau tonu i ēnei rā mō ngā uri o Ngāti Kuia mō ngā tau kei te heke mai? 

Ko tēnei he kohikohinga nō ngā kōrero o Ngāti Kuia tētahi iwi e noho ana i te Tauihu o te Waka-o-Māui. Ētahi o ngā iwi Māori he maha ngā kōrero e pā ana ki a rātou, engari ko tēnei te pukapuka tuatahi tonu ka tāia e pā ana ki a Ngāti Kuia. Ehara tēnei i te titiro hōhonu, te titiro whānui rānei i ngā kōrero engari he kohikohinga noa iho nō ngā kōrero mō Ngāti Kuia ki roto te pukapuka kotahi. Nā reira, ki te hiahia tētahi kia whāia tēnei huarahi, koinei he tīmatanga, he paku āwhina hoki mōna. 

Ka āhua toru ngā wehenga o te kōrero nei. Ka tīmata i te kupu whakataki, i muri iho ko ngā āhuatanga o te mahi, arā, i pēhea ngā kōrero i kohikohia, ā, ko te whakapapa me ngā tūhonohononga o Ngāti Kuia ki ētahi atu iwi. Ko te wāhanga tuarua, ko te kōrero o nehe rā, arā, ko ngā kōrero mō ngā atua a Tāwhaki rāua ko Māui, he kōrero mō Kupe, he whakataukī, he kōrero hoki mō ngā taniwha o te iwi. Nā, ko te wāhanga tuatoru e pā ana ki ngā tāngata rongonui o Ngāti Kuia, arā, ko Tūtepourangi, ko Tamairangi, ko Hinepoupou, ko Waikura, ko Kehaia.

year: 1995