title: Australian Legends: historical explorations of Australian masculinity and film 1970-1995.

authors: Hanley, Galina

subjects: Australia

abstract: The twin purpose of this research is to explore films as historically specific cultural texts, rather than representations of one historical moment, and to engage with historiographical debates surrounding representations of masculinity in Australian history. I do this to create a way of engaging with film and history where film is culturally representative of the past, not simply a depiction of a specific point in time. This study considers two films, George Miller's Mad Max (1979) and Stephan Elliot's The Adventures of Priscilla, Queen of the Desert (1994) to explore the relationship over time between violence, masking and landscape with the representation of performative masculinity in an Australian context.

text: Australian Legends: historical explorations of Australian masculinity and film 1970-1995. The twin purpose of this research is to explore films as historically specific cultural texts, rather than representations of one historical moment, and to engage with historiographical debates surrounding representations of masculinity in Australian history. I do this to create a way of engaging with film and history where film is culturally representative of the past, not simply a depiction of a specific point in time. This study considers two films, George Miller's Mad Max (1979) and Stephan Elliot's The Adventures of Priscilla, Queen of the Desert (1994) to explore the relationship over time between violence, masking and landscape with the representation of performative masculinity in an Australian context.

year: 2010

title: DNA methylation-associated colonic mucosal immune and defense responses in treatment-naïve pediatric ulcerative colitis

authors: Harris, R. Alan

subjects: Machine learning

abstract: Inflammatory bowel diseases (IBD) are emerging globally, indicating that environmental factors may be important in their pathogenesis. Colonic mucosal epigenetic changes, such as DNA methylation, can occur in response to the environment and have been implicated in IBD pathology. However, mucosal DNA methylation has not been examined in treatment-naïve patients. We studied DNA methylation in untreated, left sided colonic biopsy specimens using the Infinium HumanMethylation450 BeadChip array. We analyzed 22 control (C) patients, 15 untreated Crohn’s disease (CD) patients, and 9 untreated ulcerative colitis (UC) patients from two cohorts. Samples obtained at the time of clinical remission from two of the treatment-naïve UC patients were also included into the analysis. UC-specific gene expression was interrogated in a subset of adjacent samples (5 C and 5 UC) using the Affymetrix GeneChip PrimeView Human Gene Expression Arrays. Only treatment-naïve UC separated from control. One-hundred-and-twenty genes with significant expression change in UC (> 2-fold, P &lt; 0.05) were associated with differentially methylated regions (DMRs). Epigenetically associated gene expression changes (including gene expression changes in the IFITM1, ITGB2, S100A9, SLPI, SAA1, and STAT3 genes) were linked to colonic mucosal immune and defense responses. These findings underscore the relationship between epigenetic changes and inflammation in pediatric treatment-naïve UC and may have potential etiologic, diagnostic, and therapeutic relevance for IBD.

text: DNA methylation-associated colonic mucosal immune and defense responses in treatment-naïve pediatric ulcerative colitis Inflammatory bowel diseases (IBD) are emerging globally, indicating that environmental factors may be important in their pathogenesis. Colonic mucosal epigenetic changes, such as DNA methylation, can occur in response to the environment and have been implicated in IBD pathology. However, mucosal DNA methylation has not been examined in treatment-naïve patients. We studied DNA methylation in untreated, left sided colonic biopsy specimens using the Infinium HumanMethylation450 BeadChip array. We analyzed 22 control (C) patients, 15 untreated Crohn’s disease (CD) patients, and 9 untreated ulcerative colitis (UC) patients from two cohorts. Samples obtained at the time of clinical remission from two of the treatment-naïve UC patients were also included into the analysis. UC-specific gene expression was interrogated in a subset of adjacent samples (5 C and 5 UC) using the Affymetrix GeneChip PrimeView Human Gene Expression Arrays. Only treatment-naïve UC separated from control. One-hundred-and-twenty genes with significant expression change in UC (> 2-fold, P &lt; 0.05) were associated with differentially methylated regions (DMRs). Epigenetically associated gene expression changes (including gene expression changes in the IFITM1, ITGB2, S100A9, SLPI, SAA1, and STAT3 genes) were linked to colonic mucosal immune and defense responses. These findings underscore the relationship between epigenetic changes and inflammation in pediatric treatment-naïve UC and may have potential etiologic, diagnostic, and therapeutic relevance for IBD.

year: 2014

title: Birds vs. Clams: Assessing the impacts of South Island pied oystercatcher predation on Toheroa at Ripiro Beach, New Zealand

authors: Vallyon, Lolita-Maria Dolores

abstract: Managing the recovery of interacting species, such as predator and prey, is one of the most challenging factors of an ecosystem-based conservation approach. The actions taken to protect one species may be in conflict with the actions necessary to protect another. For example, the recovery of a predator in an ecosystem can lead to a significant conservation conflict between the protected predator and its protected prey. In these instances, research is required to determine whether a perceived conflict is in fact happening in order to inform proper management decisions. In New Zealand, a conservation conflict exists between an endemic, recovering shorebird, the South Island pied oystercatcher (Haematopus ostralegus finschi), and an endemic surf clam, the toheroa (Paphies ventricosa) at Ripiro Beach, Northland. The toheroa was overharvested until the populations collapsed, with commercial and recreational harvesting bans put in place by the 1970s. The toheroa has continued to decline, and the cause is currently unknown. Oystercatcher predation has been implicated as the reason toheroa populations have not recovered. There have even been calls to cull the birds to protect the clams. Currently, there is no information that would facilitate conservation management in determining the appropriate action to take. My thesis aimed to investigate the claims surrounding this perceived interspecific conflict. It sought to examine the predator-prey interactions between the two species by answering the following three questions: 1) what are the spatio-temporal associations between oystercatchers and toheroa, 2) what is the composition of the oystercatcher’s diet, and 3) what size toheroa are the birds taking? 
Bird surveys were conducted to examine the distribution of oystercatchers monthly from March 2019 to February 2020. Oystercatcher foraging behaviour was observed to collect information on prey type and prey location. Feeding holes left by oystercatcher bills at predation sites were examined to determine oystercatcher predation success. A population survey was conducted on toheroa beds exposed to oystercatcher predation versus control beds to assess if there were differences in the density and size structure between toheroa populations. 

Results did not support the hypothesis that the oystercatchers are the cause behind the limited recovery of the toheroa, but they did indicate that the birds may be having localised impacts. There was limited overlap with toheroa, as the birds were found predominantly at the southern half of Ripiro Beach and were only associated with two major toheroa beds. Observations found that bivalves are a significant food resource for oystercatchers and the birds have a high predation success rate. There was a significant difference in the density and size structure between toheroa populations in beds that were oystercatcher predation sites and those at no-predation sites. However, even in the areas with the most intense oystercatcher predation, toheroa have persisted over time. While there potentially is a small local impact, overall, the South Island pied oystercatcher is not responsible for the continuing decline of the toheroa across the whole of Ripiro Beach and are not causing devastation as claimed. 
The perceived conservation conflict between the two endemic species is likely incorrect. This research demonstrates the importance of acquiring information on interacting species prior to management action to protect one of those species. Information presented in this thesis can be used to support conservation managers in making informed decisions to protect both the toheroa and the South Island pied oystercatcher.

text: Birds vs. Clams: Assessing the impacts of South Island pied oystercatcher predation on Toheroa at Ripiro Beach, New Zealand Managing the recovery of interacting species, such as predator and prey, is one of the most challenging factors of an ecosystem-based conservation approach. The actions taken to protect one species may be in conflict with the actions necessary to protect another. For example, the recovery of a predator in an ecosystem can lead to a significant conservation conflict between the protected predator and its protected prey. In these instances, research is required to determine whether a perceived conflict is in fact happening in order to inform proper management decisions. In New Zealand, a conservation conflict exists between an endemic, recovering shorebird, the South Island pied oystercatcher (Haematopus ostralegus finschi), and an endemic surf clam, the toheroa (Paphies ventricosa) at Ripiro Beach, Northland. The toheroa was overharvested until the populations collapsed, with commercial and recreational harvesting bans put in place by the 1970s. The toheroa has continued to decline, and the cause is currently unknown. Oystercatcher predation has been implicated as the reason toheroa populations have not recovered. There have even been calls to cull the birds to protect the clams. Currently, there is no information that would facilitate conservation management in determining the appropriate action to take. My thesis aimed to investigate the claims surrounding this perceived interspecific conflict. It sought to examine the predator-prey interactions between the two species by answering the following three questions: 1) what are the spatio-temporal associations between oystercatchers and toheroa, 2) what is the composition of the oystercatcher’s diet, and 3) what size toheroa are the birds taking? 
Bird surveys were conducted to examine the distribution of oystercatchers monthly from March 2019 to February 2020. Oystercatcher foraging behaviour was observed to collect information on prey type and prey location. Feeding holes left by oystercatcher bills at predation sites were examined to determine oystercatcher predation success. A population survey was conducted on toheroa beds exposed to oystercatcher predation versus control beds to assess if there were differences in the density and size structure between toheroa populations. 

Results did not support the hypothesis that the oystercatchers are the cause behind the limited recovery of the toheroa, but they did indicate that the birds may be having localised impacts. There was limited overlap with toheroa, as the birds were found predominantly at the southern half of Ripiro Beach and were only associated with two major toheroa beds. Observations found that bivalves are a significant food resource for oystercatchers and the birds have a high predation success rate. There was a significant difference in the density and size structure between toheroa populations in beds that were oystercatcher predation sites and those at no-predation sites. However, even in the areas with the most intense oystercatcher predation, toheroa have persisted over time. While there potentially is a small local impact, overall, the South Island pied oystercatcher is not responsible for the continuing decline of the toheroa across the whole of Ripiro Beach and are not causing devastation as claimed. 
The perceived conservation conflict between the two endemic species is likely incorrect. This research demonstrates the importance of acquiring information on interacting species prior to management action to protect one of those species. Information presented in this thesis can be used to support conservation managers in making informed decisions to protect both the toheroa and the South Island pied oystercatcher.

year: 2020