Sentence:  By an effort of historical sympathy we can cast our minds back into the art of a remote past or an alien present , and enjoy the carvings of cavemen and Japanese colour prints ; but the possibility of this effort is <WSD>bound</WSD> up with that development of historical thought which is the greatest achievement of our civilization in the last two centuries , and it is utterly impossible to people in whom this development has not taken place . 
Meaning of the word marked with <WSD> tags:  closely or inseparably connected or associated with