Sentence:  Important as these differences are , they should not obscure the basic fact that by shifting the hypothalamic balance sufficiently to the parasympathetic side , we produce depressions , whereas a shift in the opposite direction causes excitatory effects and , eventually , <WSD>maniclike</WSD> changes . 
Meaning of the word marked with <WSD> tags:  resembling the mania of manic-depressive illness