Sentence:  If any one refuses to confess that the Word of God the Father is united in hypostasis to flesh, and is one Christ with His own flesh, the same being at once both God and man, let him be <WSD>anathema</WSD>. 
Meaning of the word marked with <WSD> tags:  Any person or thing anathematized, or cursed by ecclesiastical authority. (from 1520s)