Sentence:  Mrs. Hewlitt led the birthcontrol league , Mrs. Ryerson was arthritis , and way in the distance could be seen the slate roof of Ethel Littleton 's house , a roof that signified <WSD>gout</WSD> . 
Meaning of the word marked with <WSD> tags:  a painful inflammation of the big toe and foot caused by defects in uric acid metabolism resulting in deposits of the acid and its salts in the blood and joints