Sentence:  O cursed Eld the <WSD>cankerworme</WSD> of writs, / How may these rimes, so rude as doth appeare, / Hope to endure, sith workes of heauenly wits / Are quite deuourd, and brought to nought by little bits? 
Meaning of the word marked with <WSD> tags:  A corrupting or destructive force.