Sentence:  In the complexes, the direction and affinity of the hydroxy group for hydrogen bond toward the carboxy group of poly-12 may be the most important factor to control both the helical sense and an extent of the <WSD>single-handedness</WSD>, and therefore, the complexes with amino alcohols showed an intense ICD independent of the bulkiness of the substituent (R) with the same Cotton effect signs as the primary amines. 
Meaning of the word marked with <WSD> tags:  Chirality