Sentence:  At half-time, Poyet replaced Wes Brown with Liam Bridcutt in the heart of defence and sent out the rest of the players to atone for their first-half mistakes. To no <WSD>avail</WSD>. 
Meaning of the word marked with <WSD> tags:  Effect in achieving a goal or aim; purpose, use (now usually in negative constructions). (from 15thc.)