Sentence:  The "ſenſe" of the inteſtines, if exquiſite, wants a more gentle remedie; and if dull, a ſtronger: Alſo the ſenſes of the inteſtines are perceived by the courſe of diet; for thoſe that feed upon muſtard, or the like biting and more ſharp meat, without trouble, are of a more <WSD>obtuſe</WSD> ſenſe; but thoſe of an exact ſenſe, which preſently perceive the mordacity; and thoſe that are of a mean ſenſe, want a mean doſe. 
Meaning of the word marked with <WSD> tags:  Of sound, etc.: deadened, muffled, muted.