Sentence:  When I say that the great <WSD>anagrammers</WSD> seem to be men, and the most obsessive ones at that, Jan points out that some women are great <WSD>anagrammers</WSD>, too. But I note that I never see them sitting around playing Anagrams at one in the morning ... 
Meaning of the word marked with <WSD> tags:  A person who makes or finds anagrams.