Sentence:  Or else from the same Store-house, with some other poysonous Additions, they command us to take in at the Orifice "above" or "below", (just as the Physician then happens to be disposed) a Medicine equally annoying and <WSD>disgustful</WSD> to the Bowels; which relaxing the Belly, drives down all before it: And this they call a "Purge", or a "Clyster". 
Meaning of the word marked with <WSD> tags:  disgusting, vile.