Sentence:  Doth any man doubt, that if there were taken out of men's minds, vain opinions, flattering hopes, false valuations, imaginations as one would, and the like, but it would leave the minds, of a number of men, poor shrunken things, full of melancholy and <WSD>indisposition</WSD>, and unpleasing to themselves? 
Meaning of the word marked with <WSD> tags:  A bad mood or disposition.