Sentence:  If anyone asked us , after we made the remark that the suffering was a bad thing , whether we should think it relevant to what we said to learn that the incident had never occurred and no pain had been suffered at all , we should say that it made all the <WSD>difference</WSD> in the world , that what we were asserting to be bad was precisely the suffering we thought had occurred back there , that if this had not occurred , there was nothing left to be bad , and that our assertion was in that case mistaken . 
Meaning of the word marked with <WSD> tags:  a variation that deviates from the standard or norm