Sentence:  ‘Mr Rose,' says the Physician, ‘this man was brought to us from Russia. Precisely such a case of <WSD>vitiated</WSD> judgment as I describe at length in my Treatise on Madness. Mayhap you have read it?' 
Meaning of the word marked with <WSD> tags:  to spoil, make faulty; to reduce the value, quality, or effectiveness of something