Sentence:  In an <WSD>attempt</WSD> to reverse the downhill trend by stimulating the bone marrow and controlling any hemolytic component , triamcinolone , 16 mg. daily , was begun on Sept. 26 , 1958 , and continued until Feb. 18 , 1959 . 
Meaning of the word marked with <WSD> tags:  earnest and conscientious activity intended to do or accomplish something