Sentence:  Desmin (DES) mutations have been recognized as a cause of desmin-related myopathy (OMIM 601419), or desminopathy, a disease characterized by progressive limb muscle weakness and accumulation of desmin-reactive granular aggregates in the myofibers. We have studied three families with skeletal or <WSD>cardioskeletal</WSD> myopathy caused by small in-frame deletions in the desmin gene. 
Meaning of the word marked with <WSD> tags:  Relating to both cardiac muscle and skeletal muscle, two types of striated muscle (in various animals including humans) that can both be affected by, for example, desminopathies or dystrophinopathies, causing myopathies of cardiac and skeletal muscle tissue.