Sentence:  <WSD>In</WSD> any case , Dr. Calderone remarks , such problems are a couple 's own affair , and can n't always be measured by a general yardstick . 
Meaning of the word marked with <WSD> tags:  used to indicate that a statement explains or supports a previous statement; anyhow, they're quiet"; anyway, it's gone"; in any case, there was a brief scuffle"