Sentence:  Fluorescent in situ sequencing (FISSEQ) or beadbased <WSD>polony</WSD> sequencing FISSEQ involves localized amplification of single DNA molecules, using an acrylarnide gel, thus creating colonies of PCR product that are called <WSD>polonies</WSD>. 
Meaning of the word marked with <WSD> tags:  A cluster of (polymers) produced by (clonal) amplification of DNA.