Sentence:  ... 'Tis true, when once a <WSD>"Schirrus</WSD>" is formed in a glandular Part, no one can tell how it may terminate; becauſe various changes may ariſe from various Cauſes in the Conſtitution of the Perſon; and if the Juices ſhould degenerate into a highly acrid, or what the Ancients termed an atrabiliary State, the <WSD>"Schirrus</WSD>" will be ("cæteris paribus") more liable to become a "Cancer". 
Meaning of the word marked with <WSD> tags:  A hard swelling of a gland or other organ.