Sentence:  If the predisposition to the disease has arisen from a plethoric state of the system, or from a turgescence in the vessels of the head, this is to be obviated by bleeding, both generally and <WSD>topically</WSD>, but more particularly the latter; an abstemious diet and proper exercise; and by a seton in the neck. 
Meaning of the word marked with <WSD> tags:  (Applied) to a localized part of the body.