Context: CREATE TABLE table_16857_2 (mls_cup_playoffs VARCHAR, concacaf_champions_cup___champions_league VARCHAR, us_open_cup VARCHAR)
Question: How did the team place when they did not qualify for the Concaf Champions Cup but made it to Round of 16 in the U.S. Open Cup?
Answer: SELECT mls_cup_playoffs FROM table_16857_2 WHERE concacaf_champions_cup___champions_league = "Did not qualify" AND us_open_cup = "Round of 16"